Global Lipids Genetics Consortium Results
Reference
Willer CJ et al. Discovery and refinement of loci associated with lipid levels. Nat. Genet. 2013. doi:10.1038/ng.2797 [online]
Meta-Analysis Tables
The tables below summarize the results of the meta-analysis described in Willer et al (2013). Each table includes
ten columns: the marker names in build hg18 and hg19, the marker names in rsid format, the two alleles of the
SNP, the effect size associated with the SNP, the corresponding standard error, the number of individuals evaluated
for the SNP, the combined p-value for the SNP and the frequency of the first allele (the trait increasing allele)
in the 1000 Genomes European sample. The files include both genotyped and imputed SNPs and are provided in a
compressed text file to conserve space.
RESULT FILES
JOINT ANALYSIS OF METABOCHIP AND GWAS DATA
LDL Cholesterol
HDL Cholesterol
Triglycerides
Total Cholesterol
ANALYSIS OF METABOCHIP DATA
LDL Cholesterol
HDL Cholesterol
Triglycerides
Total Cholesterol
Columns in Result Files
Column Label | Description |
SNP_hg18 | Marker name in build hg18. |
SNP_hg19 | Marker name in build hg19. |
rsid | Marker name in rsid format. |
A1 | Effect allele. |
A2 | Other allele. |
Beta | Effect size. |
SE | Standard Error for Beta. |
N | The number of individuals analyzed for this marker. |
P-value | P-value after doing genomic control. |
Freq.A1.1000G.EUR | Frequency of allele A1 from 1000G EUR sample. |
Results files were slightly modified on 11/26/2013. Sites with N<50,000 were removed from the joint meta-analysis
results, sites with N<20,000 were removed from the Metabochip-only results and an rsid column was added to each dataset.
Using our GLGC data in LocusZoom (http://csg.sph.umich.edu/locuszoom).
Please e-mail Goncalo Abecasis or
Cristen Willer with comments or
suggestions.
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