University of Michigan Center for Statistical 
Genetics
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Publications (All peer reviewed)

2009

Mathias RA, Grant AV, Rafaels N, Hand T, Gao L, Vergara C, Tsai YJ, Yang M, Campbell M, Foster C, Gao P, Togias A, Hansel N, Diette G, Adkinson NF, Liu M, Faruque M, Dunston G, Watson H, Bracken MB, Hoh J, Maul P, Maul T, Jedlicka AE, Murray T, Hetmanski J, Ashworth R, Ongaco C, Hetrick K, Doheney K, Pugh E, Ford J. Eng C, Burchard EG, Sleiman PMA, Hakonarson H, Forno E, Raby BA, Weiss ST, Scott AF, Kabesch M, Liang L, Abecasis GR, Moffatt MF, Cookson WOC, Ruczinski I, Beaty TH, Barnes KC. A genome-wide association study on African-ancestry populations for asthma. Journal of Allergy and Clinical Immunology (in press)

Cookson WOC, Liang L, Abecasis GR, Moffatt MF, Lathrop M. Mapping complex disease traits with global gene expression. Nature Reviews Genetics 10, 184-194. [PDF]

Guan W*, Liang L*, Boehnke M, Abecasis GR (2009). Genotype-based matching to correct for population stratification in large-scale case-control genetic association studies. Genet Epidemiol DOI:10.1002/gepi.20403. [PDF][WEB]
* joint first author

Chen W, Liang L, Abecasis GR (2009). GWAS GUI: Graphical browser for the results of whole-genome association studies with high-dimensional phenotypes. Bioinformatics 25(2): 284-285. [PDF][WEB]

Liang L, Chen WM, Sham PC and Abecasis GR (2009). Variance Components Linkage Analysis with Repeated Measurements. Human Heredity 67: 237-247. [Article][Suppl.][WEB]

2008

Weidinger S, Gieger C, Rodriguez E, Mempel M, Klopp N, Gohlke H, Baurecht H, Wagenpfeil S, Ollert M, Ring J, Behrendt H, Heinrich J, Krämer U, von Berg A, Berdel D, Bauer CP, Herbart O, Koletzko S, Fischer G, Prokisch H, Meitinger T, Depner M, von Mutius E, Liang L, Moffat M, Cookson W, Kabesch M, Wichmann HE, Illig T (2008). Genome-wide scan on total serum IgE levels identifies FCER1A as susceptibility locus. PloS Genetics 4:e1000166, 1-9

2007

Dixon AL*, Liang L*, Moffatt MF*, Chen W, Heath S, Wong KCC, Taylor J, Gut I, Farrall M, Lathrop GM, Abecasis GR, Cookson WOC (2007). A whole-genome association study of global gene expression. Nat Genet 39, 1202-1207 | doi:10.1038/ng2109 [PDF] [WEB]
* co-first authors

Moffatt MF*, Kabesch M*, Liang L*, Dixon AL, Strachan D, Heath S, Depner M, von Berg A, Bufe A, Rietschel E, Heinzmann A, Simma B, Frischer T, Willis-Owen SAG, Wong KCC, Illig T, Vogelberg C, Weiland SK, von Mutius E, Abecasis GR3, Farrall M, Gut IG, Lathrop GM, Cookson WOC (2007). Genetic variants regulating ORMDL3 expression are determinants of susceptibility to childhood asthma. Nature 448, 470-473 | doi:10.1038/nature06014 [PDF][WEB]
* co-first authors

Liang L, Zöllner S, Abecasis GR (2007). GENOME: a rapid coalescent-based whole genome simulator. Bioinformatics 23(12):1565-1567.; doi: 10.1093/bioinformatics/btm138 [PDF] [WEB]

Libioulle C, Louis E, Hansoul S, Sandor C, Farnir F, Franchimont D, Vermeire S, Dewit O, de Vos M, Dixon A, Demarche B, Gut I, Heath S, Foglio M, Liang L, Laukens D, Mni M, Zelenika D, Van Gossum A, Rutgeerts P, Belaiche J, Lathrop M, Georges M (2007). Novel Crohn Disease Locus Identified by Genome-Wide Association Maps to a Gene Desert on 5p13.1 and Modulates Expression of PTGER4. PLoS Genet 3(4): e58, 538-543

2006

Li M, Atmaca-Sonmez P, Othman M, Branham KE, Khanna R, Wade MS, Li Y, Liang L, Zareparsi S, Swaroop A and Abecasis GR (2006).CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration. Nat Genet 38:1049-1054 [PDF]


Manuscripts in Preparations:


Liang L, Dixon AL, Moffatt MF, Chen W, Heath S, Lathrop M, Cookson WOC, Abecasis GR. Empirical analysis of the power and accuracy of genome-wide SNP imputation

 

Presentations

2008

Liang L, Morar N, Moffatt M, Lathrop GM, Abecasis GR, Cookson WOC. Expanded Catalog of eQTLs for Lymphoblastoid Cell Lines. American Society of Human Genetics 58th Annual Meeting, Philadelphia Pennsylvania, November 2008. (PLATFORM)

Guan W, Liang L, Boehnke M, Abecasis GR. Genetic Similarity Matching for Genome-wide Association Studies with Related
Individuals. American Society of Human Genetics 58th Annual Meeting, Philadelphia Pennsylvania, November 2008. (POSTER)

Ding J, Gudjonsson JE, Liang L, Nair RP, Stuart PE, Voorhees JJ, Elder JT, Abecasis GR. A genome-wide association study of gene expression in skin. American Society of Human Genetics 58th Annual Meeting, Philadelphia Pennsylvania, November 2008. (POSTER)

2007

Liang L, et al. A Genome-wide Association Study of Global Gene Expression. American Society of Human Genetics 57th Annual Meeting, San Diego California, October 2007. (PLATFORM)

Guan W, Liang L, Abecasis GR, Boehnke M. Genetic similarity matching for genome-wide association studies. American Society of Human Genetics 57th Annual Meeting, San Diego California, October 2007. (POSTER)

Chen W, Liang L, Lathrop M, Cookson WOC, Abecasis GR. Graphical browsing for whole-genome association studies of global gene expression. American Society of Human Genetics 57th Annual Meeting, San Diego California, October 2007. (POSTER)

2006

Liang L, Zöllner S, Abecasis GR. GENOME: a rapid coalescent-based whole genome simulator. American Society of Human Genetics 56th Annual Meeting, New Orleans, Louisiana, October 2006. (POSTER)

Guan W, Liang L, Boehnke M, Abecasis GR. Genetic similarity matching for genome-wide association studies. American Society of Human Genetics 56th Annual Meeting, New Orleans, Louisiana, October 2006. (POSTER)

2005

Liang L, Chen WM, Abecasis GR. Extension of Variance Components Approach to Incorporate Repeated Measurements. American Society of Human Genetics 55th Annual Meeting, Salt Lake City, Utah, October 2005. (PLATFORM)

Guan W, Liang L, Boehnke M, Abecasis GR. Matching Cases and Controls Using Genotype Data from a Whole Genome Association Study. American Society of Human Genetics 55th Annual Meeting, Salt Lake City, Utah, October 2005. (POSTER)


 
 

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