This is an initial analysis of GO term enrichment for DE results from all traits that we analyzed.

For this report we called the top 500 genes as differentially expressed. We display at minimum 5 categories for each trait, and at most 20, ordered by significance.

This report was last generated on Tue May 12 10:37:40 PM 2015

age/peer_k00_age_biopsy_all_genes.txt

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Number of significant GO categories: 49

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0090304 nucleic acid metabolic process 4166 194 0.0000000
GO:0016070 RNA metabolic process 3693 170 0.0000001
GO:0006139 nucleobase-containing compound metabolic process 5435 224 0.0000002
GO:0046483 heterocycle metabolic process 5565 225 0.0000010
GO:0006725 cellular aromatic compound metabolic process 5569 224 0.0000016
GO:0034641 cellular nitrogen compound metabolic process 5755 229 0.0000019
GO:0010467 gene expression 4322 183 0.0000022
GO:1901360 organic cyclic compound metabolic process 5728 227 0.0000027
GO:0000375 RNA splicing, via transesterification reactions 225 25 0.0000091
GO:0006396 RNA processing 676 47 0.0000162
GO:0006807 nitrogen compound metabolic process 6075 233 0.0000261
GO:0006351 transcription, DNA-templated 2952 133 0.0000577
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 220 23 0.0000806
GO:0000398 mRNA splicing, via spliceosome 220 23 0.0000806
GO:0006397 mRNA processing 404 33 0.0001004
GO:0032774 RNA biosynthetic process 3063 134 0.0001434
GO:2000112 regulation of cellular macromolecule biosynthetic process 3129 136 0.0002390
GO:0008380 RNA splicing 332 28 0.0002725
GO:0051252 regulation of RNA metabolic process 2966 130 0.0002725
GO:0010556 regulation of macromolecule biosynthetic process 3214 138 0.0002743

sex/peer_k00_sex_all_genes.txt

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Number of significant GO categories: 7

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0048704 embryonic skeletal system morphogenesis 84 12 0.0240502
GO:0010468 regulation of gene expression 3465 139 0.0240502
GO:0010467 gene expression 4322 163 0.0240502
GO:0001658 branching involved in ureteric bud morphogenesis 47 9 0.0240502
GO:0090304 nucleic acid metabolic process 4166 158 0.0240502
GO:0048706 embryonic skeletal system development 110 13 0.0307299
GO:0060675 ureteric bud morphogenesis 51 9 0.0307299

smoking/peer_k01_smoking_all_genes.txt

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Number of significant GO categories: 17

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0045333 cellular respiration 158 21 0.0000048
GO:0015980 energy derivation by oxidation of organic compounds 319 29 0.0000845
GO:0022904 respiratory electron transport chain 105 15 0.0000845
GO:0022900 electron transport chain 106 15 0.0000845
GO:0006091 generation of precursor metabolites and energy 394 31 0.0003594
GO:0015985 energy coupled proton transport, down electrochemical gradient 19 6 0.0041789
GO:0015986 ATP synthesis coupled proton transport 19 6 0.0041789
GO:0006754 ATP biosynthetic process 36 8 0.0041789
GO:0042776 mitochondrial ATP synthesis coupled proton transport 14 5 0.0119246
GO:0009206 purine ribonucleoside triphosphate biosynthetic process 46 8 0.0226644
GO:0009145 purine nucleoside triphosphate biosynthetic process 47 8 0.0238931
GO:0009060 aerobic respiration 46 8 0.0281772
GO:0055114 oxidation-reduction process 896 46 0.0281772
GO:0042773 ATP synthesis coupled electron transport 54 8 0.0281772
GO:0042775 mitochondrial ATP synthesis coupled electron transport 54 8 0.0281772
GO:0006119 oxidative phosphorylation 70 9 0.0323998
GO:0009201 ribonucleoside triphosphate biosynthetic process 52 8 0.0388474

traits/peer_k00_DBP_all_genes.txt

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Number of significant GO categories: 114

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0045333 cellular respiration 158 62 0
GO:0022904 respiratory electron transport chain 105 46 0
GO:0022900 electron transport chain 106 46 0
GO:0015980 energy derivation by oxidation of organic compounds 319 67 0
GO:0006091 generation of precursor metabolites and energy 394 73 0
GO:0055114 oxidation-reduction process 896 100 0
GO:0006119 oxidative phosphorylation 70 28 0
GO:0042773 ATP synthesis coupled electron transport 54 25 0
GO:0042775 mitochondrial ATP synthesis coupled electron transport 54 25 0
GO:0006120 mitochondrial electron transport, NADH to ubiquinone 42 22 0
GO:0009060 aerobic respiration 46 22 0
GO:0044281 small molecule metabolic process 2955 149 0
GO:0006099 tricarboxylic acid cycle 28 16 0
GO:1902600 hydrogen ion transmembrane transport 84 21 0
GO:0009123 nucleoside monophosphate metabolic process 489 45 0
GO:0009161 ribonucleoside monophosphate metabolic process 478 44 0
GO:0046034 ATP metabolic process 442 42 0
GO:0015992 proton transport 112 22 0
GO:0006818 hydrogen transport 114 22 0
GO:0009167 purine ribonucleoside monophosphate metabolic process 466 42 0

traits/peer_k00_fS_Kol_all_genes.txt

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Number of significant GO categories: 0

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0007093 mitotic cell cycle checkpoint 171 12 1
GO:0061187 regulation of chromatin silencing at rDNA 2 2 1
GO:0061188 negative regulation of chromatin silencing at rDNA 2 2 1
GO:0090304 nucleic acid metabolic process 4166 133 1
GO:0033169 histone H3-K9 demethylation 7 3 1

traits/peer_k00_fS_Kol_LDL_c_all_genes.txt

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Number of significant GO categories: 0

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0044255 cellular lipid metabolic process 772 40 0.2734593
GO:0051028 mRNA transport 124 13 0.2734593
GO:0006066 alcohol metabolic process 315 21 0.2734593
GO:2000392 regulation of lamellipodium morphogenesis 4 3 0.2734593
GO:0006629 lipid metabolic process 1015 47 0.2734593

traits/peer_k00_fS_Krea_all_genes.txt

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Number of significant GO categories: 5

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0090304 nucleic acid metabolic process 4166 163 0.0045424
GO:0010467 gene expression 4322 167 0.0045424
GO:0016070 RNA metabolic process 3693 146 0.0139873
GO:0006396 RNA processing 676 40 0.0263621
GO:0042254 ribosome biogenesis 167 16 0.0440197

traits/peer_k00_GL30_all_genes.txt

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Number of significant GO categories: 37

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0022904 respiratory electron transport chain 105 21 0.0000000
GO:0022900 electron transport chain 106 21 0.0000000
GO:0045333 cellular respiration 158 24 0.0000000
GO:0015980 energy derivation by oxidation of organic compounds 319 33 0.0000002
GO:0006091 generation of precursor metabolites and energy 394 37 0.0000002
GO:0055114 oxidation-reduction process 896 58 0.0000036
GO:0006119 oxidative phosphorylation 70 14 0.0000064
GO:1902600 hydrogen ion transmembrane transport 84 15 0.0000082
GO:0044281 small molecule metabolic process 2955 131 0.0000279
GO:0042773 ATP synthesis coupled electron transport 54 11 0.0001466
GO:0042775 mitochondrial ATP synthesis coupled electron transport 54 11 0.0001466
GO:0015992 proton transport 112 15 0.0003555
GO:0006818 hydrogen transport 114 15 0.0004231
GO:0006120 mitochondrial electron transport, NADH to ubiquinone 42 9 0.0009493
GO:0015985 energy coupled proton transport, down electrochemical gradient 19 6 0.0052577
GO:0015986 ATP synthesis coupled proton transport 19 6 0.0052577
GO:0044710 single-organism metabolic process 4810 179 0.0094168
GO:0044711 single-organism biosynthetic process 1254 62 0.0102598
GO:0009152 purine ribonucleotide biosynthetic process 185 17 0.0129999
GO:0046034 ATP metabolic process 442 29 0.0179626

traits/peer_k00_ratio_apob_apoa1_all_genes.txt

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Number of significant GO categories: 122

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0045321 leukocyte activation 561 52 0.00e+00
GO:0046649 lymphocyte activation 480 46 0.00e+00
GO:0001775 cell activation 767 58 0.00e+00
GO:0002376 immune system process 1936 102 0.00e+00
GO:0042110 T cell activation 347 35 0.00e+00
GO:0002682 regulation of immune system process 997 64 1.00e-07
GO:0006955 immune response 1137 68 2.00e-07
GO:0023052 signaling 4496 175 3.00e-06
GO:0044700 single organism signaling 4496 175 3.00e-06
GO:0050896 response to stimulus 6126 219 6.30e-06
GO:0007165 signal transduction 4077 161 6.30e-06
GO:0007154 cell communication 4559 175 6.60e-06
GO:0050776 regulation of immune response 666 45 6.60e-06
GO:0002694 regulation of leukocyte activation 340 30 7.20e-06
GO:0050865 regulation of cell activation 366 31 1.02e-05
GO:0007166 cell surface receptor signaling pathway 2374 106 1.33e-05
GO:0051249 regulation of lymphocyte activation 298 27 2.04e-05
GO:0002684 positive regulation of immune system process 610 41 3.16e-05
GO:0006952 defense response 1178 62 4.84e-05
GO:0051716 cellular response to stimulus 4976 182 5.57e-05

traits/peer_k00_S_Ca_30_all_genes.txt

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Number of significant GO categories: 0

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0044699 single-organism process 10471 351 1
GO:0065008 regulation of biological quality 2575 107 1
GO:0048518 positive regulation of biological process 3684 144 1
GO:0006950 response to stress 2909 116 1
GO:0006887 exocytosis 286 20 1

traits/peer_k00_total_daily_physical_activity_all_genes.txt

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Number of significant GO categories: 0

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0019219 regulation of nucleobase-containing compound metabolic process 3668 127 0.4217889
GO:0016070 RNA metabolic process 3693 127 0.4217889
GO:0051171 regulation of nitrogen compound metabolic process 3754 129 0.4217889
GO:0009889 regulation of biosynthetic process 3367 117 0.4217889
GO:0090304 nucleic acid metabolic process 4166 139 0.4217889

traits/peer_k01_fS_Trigly_all_genes.txt

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Number of significant GO categories: 0

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0055114 oxidation-reduction process 896 50 0.0663645
GO:0010676 positive regulation of cellular carbohydrate metabolic process 44 8 0.1623631
GO:0009063 cellular amino acid catabolic process 103 12 0.1623631
GO:0070972 protein localization to endoplasmic reticulum 128 13 0.1623631
GO:0006413 translational initiation 167 15 0.1623631

traits/peer_k01_GL120_all_genes.txt

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Number of significant GO categories: 0

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0006614 SRP-dependent cotranslational protein targeting to membrane 107 10 1
GO:0006613 cotranslational protein targeting to membrane 109 10 1
GO:0045047 protein targeting to ER 110 10 1
GO:0044267 cellular protein metabolic process 3491 130 1
GO:0072599 establishment of protein localization to endoplasmic reticulum 111 10 1

traits/peer_k01_GL60_all_genes.txt

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Number of significant GO categories: 0

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0035924 cellular response to vascular endothelial growth factor stimulus 31 7 0.3361095
GO:0032879 regulation of localization 1622 73 0.3361095
GO:0030154 cell differentiation 2703 110 0.3361095
GO:0015711 organic anion transport 293 21 0.3361095
GO:0038084 vascular endothelial growth factor signaling pathway 19 5 0.3361095

traits/peer_k01_S_ALAT_all_genes.txt

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Number of significant GO categories: 0

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0032370 positive regulation of lipid transport 34 7 0.3727543
GO:0022412 cellular process involved in reproduction in multicellular organism 186 14 1.0000000
GO:0055099 response to high density lipoprotein particle 2 2 1.0000000
GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process 2 2 1.0000000
GO:0032368 regulation of lipid transport 63 7 1.0000000

traits/peer_k01_S_hs_CRP_all_genes.txt

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Number of significant GO categories: 0

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0044707 single-multicellular organism process 4822 177 0.0895194
GO:0032501 multicellular organismal process 4965 181 0.0895194
GO:1901342 regulation of vasculature development 172 16 0.0895194
GO:0043085 positive regulation of catalytic activity 1225 60 0.0895194
GO:0044093 positive regulation of molecular function 1425 67 0.0895194

traits/peer_k01_strenuous_physical_activity_all_genes.txt

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Number of significant GO categories: 0

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0046165 alcohol biosynthetic process 124 12 1
GO:0044283 small molecule biosynthetic process 388 24 1
GO:0016126 sterol biosynthetic process 47 7 1
GO:0001836 release of cytochrome c from mitochondria 51 7 1
GO:0090199 regulation of release of cytochrome c from mitochondria 39 6 1

traits/peer_k01_S_Uraat_all_genes.txt

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Number of significant GO categories: 0

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0042221 response to chemical 2788 111 1
GO:0009063 cellular amino acid catabolic process 103 11 1
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 646 35 1
GO:0097529 myeloid leukocyte migration 104 10 1
GO:1901606 alpha-amino acid catabolic process 79 9 1

traits/peer_k01_WHR_all_genes.txt

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Number of significant GO categories: 5

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0032501 multicellular organismal process 4965 195 0.0002969
GO:0044707 single-multicellular organism process 4822 187 0.0010275
GO:0048856 anatomical structure development 3825 150 0.0366749
GO:0007275 multicellular organismal development 3705 146 0.0366749
GO:0032502 developmental process 4292 164 0.0366749

traits/peer_k03_bmi_all_genes.txt

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Number of significant GO categories: 97

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0006415 translational termination 95 33 0
GO:0006414 translational elongation 121 36 0
GO:0006614 SRP-dependent cotranslational protein targeting to membrane 107 34 0
GO:0006613 cotranslational protein targeting to membrane 109 34 0
GO:0045047 protein targeting to ER 110 34 0
GO:0072599 establishment of protein localization to endoplasmic reticulum 111 34 0
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 118 35 0
GO:0070972 protein localization to endoplasmic reticulum 128 36 0
GO:0006413 translational initiation 167 39 0
GO:0043624 cellular protein complex disassembly 174 38 0
GO:0043241 protein complex disassembly 195 39 0
GO:0032984 macromolecular complex disassembly 205 39 0
GO:0000956 nuclear-transcribed mRNA catabolic process 184 37 0
GO:0006612 protein targeting to membrane 171 35 0
GO:0006402 mRNA catabolic process 196 37 0
GO:0019083 viral transcription 158 33 0
GO:0019080 viral gene expression 168 33 0
GO:0006401 RNA catabolic process 222 38 0
GO:0006412 translation 496 56 0
GO:0044033 multi-organism metabolic process 178 33 0

traits/peer_k03_fS_C_pept_30_all_genes.txt

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Number of significant GO categories: 46

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0006413 translational initiation 167 29 0.0000000
GO:0006414 translational elongation 121 22 0.0000000
GO:0070972 protein localization to endoplasmic reticulum 128 22 0.0000000
GO:0006412 translation 496 45 0.0000000
GO:0006415 translational termination 95 19 0.0000000
GO:0006614 SRP-dependent cotranslational protein targeting to membrane 107 19 0.0000001
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 118 20 0.0000001
GO:0006613 cotranslational protein targeting to membrane 109 19 0.0000001
GO:0045047 protein targeting to ER 110 19 0.0000001
GO:0072599 establishment of protein localization to endoplasmic reticulum 111 19 0.0000002
GO:0019083 viral transcription 158 22 0.0000005
GO:0019080 viral gene expression 168 22 0.0000014
GO:0043241 protein complex disassembly 195 24 0.0000016
GO:0044033 multi-organism metabolic process 178 22 0.0000036
GO:0032984 macromolecular complex disassembly 205 24 0.0000036
GO:0043624 cellular protein complex disassembly 174 22 0.0000036
GO:0006612 protein targeting to membrane 171 20 0.0000556
GO:0006402 mRNA catabolic process 196 21 0.0001472
GO:0000956 nuclear-transcribed mRNA catabolic process 184 20 0.0001978
GO:0006401 RNA catabolic process 222 22 0.0002732

traits/peer_k03_fS_C_pept_all_genes.txt

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Number of significant GO categories: 107

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0006614 SRP-dependent cotranslational protein targeting to membrane 107 41 0
GO:0006415 translational termination 95 39 0
GO:0006613 cotranslational protein targeting to membrane 109 41 0
GO:0045047 protein targeting to ER 110 41 0
GO:0072599 establishment of protein localization to endoplasmic reticulum 111 41 0
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 118 42 0
GO:0070972 protein localization to endoplasmic reticulum 128 42 0
GO:0006414 translational elongation 121 41 0
GO:0006413 translational initiation 167 46 0
GO:0006612 protein targeting to membrane 171 42 0
GO:0019083 viral transcription 158 40 0
GO:0019080 viral gene expression 168 40 0
GO:0043624 cellular protein complex disassembly 174 41 0
GO:0000956 nuclear-transcribed mRNA catabolic process 184 42 0
GO:0044033 multi-organism metabolic process 178 40 0
GO:0043241 protein complex disassembly 195 42 0
GO:0006402 mRNA catabolic process 196 42 0
GO:0032984 macromolecular complex disassembly 205 42 0
GO:0006401 RNA catabolic process 222 43 0
GO:0006412 translation 496 62 0

traits/peer_k03_fS_Kol_HDL_all_genes.txt

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Number of significant GO categories: 16

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0006413 translational initiation 167 21 0.0000268
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 118 16 0.0001653
GO:0006415 translational termination 95 14 0.0001653
GO:0006412 translation 496 36 0.0001653
GO:0006414 translational elongation 121 16 0.0001653
GO:0070972 protein localization to endoplasmic reticulum 128 15 0.0015624
GO:0006614 SRP-dependent cotranslational protein targeting to membrane 107 13 0.0037161
GO:0006613 cotranslational protein targeting to membrane 109 13 0.0039448
GO:0045047 protein targeting to ER 110 13 0.0039448
GO:0072599 establishment of protein localization to endoplasmic reticulum 111 13 0.0042059
GO:0006402 mRNA catabolic process 196 18 0.0080103
GO:0000956 nuclear-transcribed mRNA catabolic process 184 17 0.0107074
GO:0006401 RNA catabolic process 222 19 0.0107721
GO:0043624 cellular protein complex disassembly 174 16 0.0169592
GO:0043933 macromolecular complex subunit organization 1450 69 0.0212610
GO:0019083 viral transcription 158 14 0.0400695

traits/peer_k03_GL0_all_genes.txt

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Number of significant GO categories: 4

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0006413 translational initiation 167 18 0.0068013
GO:0019395 fatty acid oxidation 77 12 0.0128646
GO:0034440 lipid oxidation 79 12 0.0128646
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 118 13 0.0474046
GO:0055091 phospholipid homeostasis 7 4 0.0513529

traits/peer_k03_S_Ca_all_genes.txt

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Number of significant GO categories: 0

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0071810 regulation of fever generation by regulation of prostaglandin secretion 2 2 1
GO:0071812 positive regulation of fever generation by positive regulation of prostaglandin secretion 2 2 1
GO:0071847 TNFSF11-mediated signaling pathway 2 2 1
GO:0071848 positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling 2 2 1
GO:0044087 regulation of cellular component biogenesis 436 23 1

traits/peer_k03_S_Insu_30_all_genes.txt

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Number of significant GO categories: 46

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0006413 translational initiation 167 25 0.0000001
GO:0006415 translational termination 95 17 0.0000034
GO:0006414 translational elongation 121 19 0.0000038
GO:0070972 protein localization to endoplasmic reticulum 128 19 0.0000065
GO:0006614 SRP-dependent cotranslational protein targeting to membrane 107 17 0.0000098
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 118 18 0.0000098
GO:0006613 cotranslational protein targeting to membrane 109 17 0.0000100
GO:0045047 protein targeting to ER 110 17 0.0000100
GO:0072599 establishment of protein localization to endoplasmic reticulum 111 17 0.0000106
GO:0019083 viral transcription 158 20 0.0000191
GO:0019752 carboxylic acid metabolic process 829 54 0.0000302
GO:0006412 translation 496 38 0.0000392
GO:0019080 viral gene expression 168 20 0.0000434
GO:0044033 multi-organism metabolic process 178 20 0.0001061
GO:0043624 cellular protein complex disassembly 174 20 0.0001061
GO:0006091 generation of precursor metabolites and energy 394 32 0.0001061
GO:0043241 protein complex disassembly 195 21 0.0001550
GO:0006082 organic acid metabolic process 944 56 0.0003220
GO:0032984 macromolecular complex disassembly 205 21 0.0003220
GO:0015980 energy derivation by oxidation of organic compounds 319 27 0.0003554

traits/peer_k03_S_Insu_all_genes.txt

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Number of significant GO categories: 57

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0006614 SRP-dependent cotranslational protein targeting to membrane 107 33 0
GO:0006613 cotranslational protein targeting to membrane 109 33 0
GO:0045047 protein targeting to ER 110 33 0
GO:0006415 translational termination 95 31 0
GO:0072599 establishment of protein localization to endoplasmic reticulum 111 33 0
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 118 34 0
GO:0070972 protein localization to endoplasmic reticulum 128 34 0
GO:0006414 translational elongation 121 33 0
GO:0006413 translational initiation 167 37 0
GO:0019083 viral transcription 158 33 0
GO:0006612 protein targeting to membrane 171 34 0
GO:0019080 viral gene expression 168 33 0
GO:0044033 multi-organism metabolic process 178 33 0
GO:0000956 nuclear-transcribed mRNA catabolic process 184 34 0
GO:0006402 mRNA catabolic process 196 34 0
GO:0043624 cellular protein complex disassembly 174 32 0
GO:0006412 translation 496 53 0
GO:0043241 protein complex disassembly 195 33 0
GO:0006401 RNA catabolic process 222 35 0
GO:0032984 macromolecular complex disassembly 205 33 0

traits/peer_k03_S_LipoA1_all_genes.txt

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Number of significant GO categories: 0

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0015980 energy derivation by oxidation of organic compounds 319 20 1
GO:0006091 generation of precursor metabolites and energy 394 23 1
GO:0022904 respiratory electron transport chain 105 9 1
GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 2 2 1
GO:0022900 electron transport chain 106 9 1

traits/peer_k04_B_GHb_A1C_all_genes.txt

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Number of significant GO categories: 0

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0051168 nuclear export 136 15 0.0674858
GO:0006405 RNA export from nucleus 80 11 0.0674858
GO:0050657 nucleic acid transport 144 15 0.0674858
GO:0050658 RNA transport 144 15 0.0674858
GO:0051236 establishment of RNA localization 144 15 0.0674858

traits/peer_k04_daily_energy_expenditure_all_genes.txt

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Number of significant GO categories: 0

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0016568 chromatin modification 502 29 1
GO:0060026 convergent extension 17 4 1
GO:0016570 histone modification 343 22 1
GO:0050686 negative regulation of mRNA processing 17 4 1
GO:0016569 covalent chromatin modification 348 22 1

traits/peer_k06_S_GT_all_genes.txt

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Number of significant GO categories: 0

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0001977 renal system process involved in regulation of blood volume 14 5 0.2934926
GO:0003093 regulation of glomerular filtration 10 4 0.4248831
GO:0016042 lipid catabolic process 208 17 0.4248831
GO:0003071 renal system process involved in regulation of systemic arterial blood pressure 20 5 0.4259082
GO:0051270 regulation of cellular component movement 555 32 0.4259082

traits/peer_k06_S_LipoB_all_genes.txt

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Number of significant GO categories: 0

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0010038 response to metal ion 208 16 0.2593173
GO:0015908 fatty acid transport 61 8 0.2593173
GO:0016042 lipid catabolic process 208 15 0.2593173
GO:0005975 carbohydrate metabolic process 751 35 0.2593173
GO:0015849 organic acid transport 211 15 0.2593173

traits/peer_k07_SBP_all_genes.txt

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Number of significant GO categories: 0

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0032819 positive regulation of natural killer cell proliferation 4 3 0.7837656
GO:0032817 regulation of natural killer cell proliferation 5 3 0.9857521
GO:0009755 hormone-mediated signaling pathway 73 9 0.9857521
GO:0001787 natural killer cell proliferation 6 3 0.9857521
GO:0032740 positive regulation of interleukin-17 production 7 3 1.0000000

ngt_vs_t2d/peer_k03_all_genes.txt

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Number of significant GO categories: 2

Number of DE genes: 500

category term numInCat numDEInCat q.value
GO:0022904 respiratory electron transport chain 105 13 0.0124470
GO:0022900 electron transport chain 106 13 0.0124470
GO:0045333 cellular respiration 158 15 0.0575483
GO:2001256 regulation of store-operated calcium entry 5 3 0.8274762
GO:0006120 mitochondrial electron transport, NADH to ubiquinone 42 6 1.0000000