Number of significant go terms: 418
fit.cluster Concept.ID Concept.name ontology n.genes coeff odds.ratio status p.value FDR sig.genes
GO:1902679 1 GO:1902679 negative regulation of RNA biosynthetic process GOBP 834 0.1924448 1.2122096 up 0.0006749 0.0117565 4782 1655 3068 54927 7071 142 6427 25824 9093 5245 8242 92140 80139 7088 708 23405 6944 4781 7376 23028 54623 58487 23408 2308 64324 10524 3727 3148 9575 2274 11278 138151 9682 1488 22823 8462 55915 25855 5727 2122 54567 1942 6839 7481 167465 5971 55897 7421 90665
GO:1903507 1 GO:1903507 negative regulation of nucleic acid-templated transcription GOBP 821 0.1879696 1.2067969 up 0.0009712 0.0155128 4782 1655 3068 54927 7071 142 6427 25824 9093 5245 8242 92140 80139 7088 708 23405 6944 4781 7376 23028 54623 58487 23408 2308 64324 10524 3727 3148 9575 2274 11278 138151 9682 1488 22823 8462 55915 25855 5727 2122 54567 1942 6839 7481 167465 5971 55897 7421 90665
GO:0045892 1 GO:0045892 negative regulation of transcription, DNA-templated GOBP 792 0.1674748 1.1823154 up 0.0039388 0.0447536 4782 1655 3068 54927 7071 142 25824 9093 5245 8242 92140 80139 7088 708 23405 6944 4781 7376 23028 54623 58487 23408 2308 64324 10524 3727 3148 9575 2274 11278 138151 9682 1488 22823 8462 55915 25855 5727 2122 54567 1942 6839 7481 167465 5971 55897 7421
GO:0051186 2 GO:0051186 cofactor metabolic process GOBP 243 -0.6969971 0.4980787 down 0.0000000 0.0000000 5166 23171 5164 1738 5160 8803 231 8801 5162 1737 25824 10135 4522 54704 5096 1355 27430 51004 8574 6470 4337 11019 10797 51805 84693 349565 5095 3145 57107 641371 283927 23729 51268 57834
GO:0006732 2 GO:0006732 coenzyme metabolic process GOBP 187 -0.6529427 0.5205118 down 0.0000000 0.0000000 5166 23171 5164 1738 5160 8803 8801 5162 1737 25824 10135 4522 54704 27430 51004 6470 4337 11019 10797 51805 84693 349565 57107 641371 283927 23729 51268 57834
GO:0051188 2 GO:0051188 cofactor biosynthetic process GOBP 118 -0.7333915 0.4802773 down 0.0000000 0.0000000 5166 5164 1738 5160 8803 5162 1737 54704 1355 27430 51004 4337 11019 51805 349565 3145 57107
GO:0009108 2 GO:0009108 coenzyme biosynthetic process GOBP 84 -0.7502207 0.4722623 down 0.0000000 0.0000003 5166 5164 1738 5160 5162 1737 54704 27430 51004 4337 11019 51805 349565 57107
GO:0009083 3 GO:0009083 branched-chain amino acid catabolic process GOBP 26 -1.2894821 0.2754134 down 0.0000000 0.0000000 1738 36 11112 4329 10295 587 594
GO:0009081 3 GO:0009081 branched-chain amino acid metabolic process GOBP 30 -1.1858693 0.3054805 down 0.0000000 0.0000000 1738 36 11112 4329 10295 587 594
GO:1901661 3 GO:1901661 quinone metabolic process GOBP 30 -1.0006933 0.3676245 down 0.0000000 0.0000018 231 51004 8574 51805 57107 57834
GO:0031570 3 GO:0031570 DNA integrity checkpoint GOBP 148 0.5530968 1.7386288 up 0.0000019 0.0000728 9261 5884 9575 84142 8738 83695 79858 29935
GO:0000077 3 GO:0000077 DNA damage checkpoint GOBP 139 0.5399966 1.7160011 up 0.0000061 0.0002007 9261 5884 9575 84142 8738 83695 79858 29935
GO:0042181 3 GO:0042181 ketone biosynthetic process GOBP 29 -0.8601648 0.4230923 down 0.0000264 0.0008017 6342 51004 51805 57107
GO:0040001 3 GO:0040001 establishment of mitotic spindle localization GOBP 11 1.1311846 3.0993256 up 0.0000274 0.0008272 6993 51203
GO:0017004 3 GO:0017004 cytochrome complex assembly GOBP 17 -0.9432163 0.3893735 down 0.0000340 0.0010122 55245 1355 29090 90639
GO:0006743 3 GO:0006743 ubiquinone metabolic process GOBP 16 -1.0486020 0.3504273 down 0.0000446 0.0012877 51004 51805 57107
GO:0006744 3 GO:0006744 ubiquinone biosynthetic process GOBP 16 -1.0486020 0.3504273 down 0.0000446 0.0012877 51004 51805 57107
GO:1901663 3 GO:1901663 quinone biosynthetic process GOBP 18 -1.0139508 0.3627829 down 0.0000540 0.0014837 51004 51805 57107
GO:0031123 3 GO:0031123 RNA 3'-end processing GOBP 134 0.5216187 1.6847526 up 0.0000545 0.0014881 6427 54623 6832 1479 25888 1973
GO:0000380 3 GO:0000380 alternative mRNA splicing, via spliceosome GOBP 28 0.8906708 2.4367636 up 0.0000562 0.0015268 1655 4670 10291 5936
GO:0033013 3 GO:0033013 tetrapyrrole metabolic process GOBP 53 -0.6958843 0.4986333 down 0.0000845 0.0021326 8803 1355 3145 25974
GO:0043038 3 GO:0043038 amino acid activation GOBP 72 -0.6420713 0.5262014 down 0.0000867 0.0021622 5859 4677 51520 80222 5188 79731
GO:0043039 3 GO:0043039 tRNA aminoacylation GOBP 72 -0.6420713 0.5262014 down 0.0000867 0.0021622 5859 4677 51520 80222 5188 79731
GO:2000045 3 GO:2000045 regulation of G1/S transition of mitotic cell cycle GOBP 108 0.5169947 1.6769802 up 0.0001156 0.0027787 1654 138151 8738
GO:0046459 3 GO:0046459 short-chain fatty acid metabolic process GOBP 10 -1.0410292 0.3530911 down 0.0001160 0.0027787 5096 84693 5095 116285
GO:1902806 3 GO:1902806 regulation of cell cycle G1/S phase transition GOBP 113 0.5000886 1.6488674 up 0.0001566 0.0034987 1654 493 138151 8738
GO:0042092 3 GO:0042092 type 2 immune response GOBP 11 1.0670155 2.9066915 up 0.0001574 0.0034987 3606
GO:0006369 3 GO:0006369 termination of RNA polymerase II transcription GOBP 46 0.7002044 2.0141644 up 0.0001783 0.0038922 6427 1479 25888
GO:0031124 3 GO:0031124 mRNA 3'-end processing GOBP 114 0.5208538 1.6834643 up 0.0001830 0.0039655 6427 54623 1479 25888 1973
GO:0006418 3 GO:0006418 tRNA aminoacylation for protein translation GOBP 67 -0.6317569 0.5316569 down 0.0002039 0.0043575 5859 4677 51520 80222 79731
GO:0043414 3 GO:0043414 macromolecule methylation GOBP 170 0.4471831 1.5639006 up 0.0002615 0.0053650 54623 64324 51504 28989 22823 79918 6839 196541
GO:0051293 3 GO:0051293 establishment of spindle localization GOBP 20 0.9267039 2.5261690 up 0.0003170 0.0063893 6993 51203
GO:0051653 3 GO:0051653 spindle localization GOBP 20 0.9267039 2.5261690 up 0.0003170 0.0063893 6993 51203
GO:0001836 3 GO:0001836 release of cytochrome c from mitochondria GOBP 53 -0.6018938 0.5477733 down 0.0003674 0.0071563 6648 10059 10105 26355 5071 92609 10018 79017 578
GO:0046471 3 GO:0046471 phosphatidylglycerol metabolic process GOBP 31 -0.7245141 0.4845599 down 0.0003850 0.0074665 30968 376497 81579 54675 6901 255189
GO:0008535 3 GO:0008535 respiratory chain complex IV assembly GOBP 12 -0.9580117 0.3836549 down 0.0003978 0.0076518 1355 29090 90639
GO:0006353 3 GO:0006353 DNA-templated transcription, termination GOBP 93 0.5105635 1.6662299 up 0.0004883 0.0091260 6427 84265 4331 1479 10621 51728 25888
GO:0019748 3 GO:0019748 secondary metabolic process GOBP 21 -0.7689053 0.4635202 down 0.0004956 0.0092245 231 51004 8574 2053
GO:0042590 3 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I GOBP 73 0.5409676 1.7176680 up 0.0006131 0.0109692
GO:0006595 3 GO:0006595 polyamine metabolic process GOBP 21 -0.8135294 0.4432908 down 0.0006436 0.0114319 2805 4947 112483 6611
GO:0022613 3 GO:0022613 ribonucleoprotein complex biogenesis GOBP 287 0.3306849 1.3919211 up 0.0006439 0.0114319 51119 1654 10291 7248 708 23405 115752 131870 64979 83640
GO:0022618 3 GO:0022618 ribonucleoprotein complex assembly GOBP 163 0.4317698 1.5399806 up 0.0006561 0.0116029 51119 1654 10291 708 23405 83640
GO:0030217 3 GO:0030217 T cell differentiation GOBP 85 0.5236971 1.6882577 up 0.0006595 0.0116039 6097 387357
GO:0009065 3 GO:0009065 glutamine family amino acid catabolic process GOBP 16 -0.8651699 0.4209800 down 0.0006639 0.0116086 493 2746 8659
GO:0002479 3 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent GOBP 71 0.5408335 1.7174377 up 0.0007274 0.0124363
GO:0070098 3 GO:0070098 chemokine-mediated signaling pathway GOBP 43 0.6811261 1.9761017 up 0.0007394 0.0125387 2185 4283 1234 2829
GO:0043950 3 GO:0043950 positive regulation of cAMP-mediated signaling GOBP 10 1.0224096 2.7798852 up 0.0007983 0.0131153 4283
GO:0044774 3 GO:0044774 mitotic DNA integrity checkpoint GOBP 94 0.4859996 1.6257994 up 0.0008039 0.0131153 8738 79858
GO:0034612 3 GO:0034612 response to tumor necrosis factor GOBP 93 0.4940138 1.6388812 up 0.0008389 0.0136354 204851 5071 2185
GO:0048247 3 GO:0048247 lymphocyte chemotaxis GOBP 18 0.8746847 2.3981189 up 0.0010448 0.0164597 2185 4283 6288
GO:0042073 3 GO:0042073 intraciliary transport GOBP 25 0.8084815 2.2444971 up 0.0010607 0.0166534 26146 92104
GO:0002474 3 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I GOBP 104 0.4632024 1.5891550 up 0.0011134 0.0173629 1636
GO:0006337 3 GO:0006337 nucleosome disassembly GOBP 14 0.9177594 2.5036743 up 0.0011934 0.0182411 6599
GO:0032986 3 GO:0032986 protein-DNA complex disassembly GOBP 14 0.9177594 2.5036743 up 0.0011934 0.0182411 6599
GO:0051084 3 GO:0051084 'de novo' posttranslational protein folding GOBP 36 0.6784830 1.9708856 up 0.0012352 0.0186336 22948 10383 6904 957 6903
GO:0044773 3 GO:0044773 mitotic DNA damage checkpoint GOBP 90 0.4781486 1.6130852 up 0.0012882 0.0192442 8738 79858
GO:0006768 3 GO:0006768 biotin metabolic process GOBP 11 -0.9266866 0.3958632 down 0.0013290 0.0197598 5096 5095
GO:2000134 3 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle GOBP 91 0.4736888 1.6059071 up 0.0013609 0.0200060 138151 8738
GO:1902807 3 GO:1902807 negative regulation of cell cycle G1/S phase transition GOBP 92 0.4704712 1.6007482 up 0.0013927 0.0204089 138151 8738
GO:0000462 3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GOBP 27 0.7509967 2.1191110 up 0.0014715 0.0213599
GO:0006458 3 GO:0006458 'de novo' protein folding GOBP 41 0.6361729 1.8892367 up 0.0015682 0.0225249 22948 10383 6904 957 51182 6903
GO:0042088 3 GO:0042088 T-helper 1 type immune response GOBP 16 0.8836147 2.4196301 up 0.0016726 0.0236103 3606
GO:0032048 3 GO:0032048 cardiolipin metabolic process GOBP 15 -0.8619716 0.4223286 down 0.0016946 0.0237759 30968 376497 54675 6901
GO:0032481 3 GO:0032481 positive regulation of type I interferon production GOBP 90 0.5013048 1.6508739 up 0.0017129 0.0239601 1654 84265 10621 51728 11277
GO:0016137 3 GO:0016137 glycoside metabolic process GOBP 14 -0.8391779 0.4320656 down 0.0017193 0.0239764 231 8574
GO:0000209 3 GO:0000209 protein polyubiquitination GOBP 187 0.3374305 1.4013422 up 0.0019372 0.0267293 267 10477 84937 5071 51529 10193 92912 6049 9666 57531
GO:0051028 3 GO:0051028 mRNA transport GOBP 76 0.5103138 1.6658138 up 0.0019864 0.0269689 6427
GO:0018023 3 GO:0018023 peptidyl-lysine trimethylation GOBP 15 0.8901715 2.4355472 up 0.0020699 0.0278557 6839
GO:0008202 3 GO:0008202 steroid metabolic process GOBP 178 -0.3342798 0.7158535 down 0.0021138 0.0283649 7555 231 6097 6342 2224 30 2053 8578 1717 10682 1571 7421 8714
GO:0000096 3 GO:0000096 sulfur amino acid metabolic process GOBP 47 -0.5980662 0.5498740 down 0.0021506 0.0287738 2805 2730 6611 7263
GO:1903320 3 GO:1903320 regulation of protein modification by small protein conjugation or removal GOBP 221 0.3102271 1.3637347 up 0.0022827 0.0301573 9093 5071 23560 51529 2185 83932
GO:0030330 3 GO:0030330 DNA damage response, signal transduction by p53 class mediator GOBP 112 0.4188293 1.5201809 up 0.0022866 0.0301573 1655 23028 10524 8738
GO:0070646 3 GO:0070646 protein modification by small protein removal GOBP 124 0.4279458 1.5341030 up 0.0023006 0.0302547 8078 56970 143684 84132
GO:0000381 3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome GOBP 21 0.8034473 2.2332263 up 0.0024846 0.0325818 1655 10291 5936
GO:0071222 3 GO:0071222 cellular response to lipopolysaccharide GOBP 67 0.5166057 1.6763280 up 0.0025116 0.0327500 92140 54623 3148 3606 3929 23729 1234
GO:0006978 3 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GOBP 13 0.8968589 2.4518893 up 0.0025968 0.0334830 10524
GO:0045580 3 GO:0045580 regulation of T cell differentiation GOBP 45 0.5997443 1.8216529 up 0.0026749 0.0343542
GO:0042754 3 GO:0042754 negative regulation of circadian rhythm GOBP 9 0.9878895 2.6855606 up 0.0026814 0.0343542 6839
GO:1903321 3 GO:1903321 negative regulation of protein modification by small protein conjugation or removal GOBP 113 0.4028904 1.4961429 up 0.0027642 0.0351501 23560 51529
GO:0006406 3 GO:0006406 mRNA export from nucleus GOBP 74 0.4987869 1.6467225 up 0.0027873 0.0353473 6427
GO:0007076 3 GO:0007076 mitotic chromosome condensation GOBP 14 0.9129313 2.4916155 up 0.0028014 0.0354287 51203
GO:0044819 3 GO:0044819 mitotic G1/S transition checkpoint GOBP 75 0.4827077 1.6204562 up 0.0028498 0.0355696 8738
GO:0031571 3 GO:0031571 mitotic G1 DNA damage checkpoint GOBP 74 0.4843708 1.6231533 up 0.0029319 0.0358375 8738
GO:0006584 3 GO:0006584 catecholamine metabolic process GOBP 20 0.8079829 2.2433784 up 0.0029423 0.0358375 5071 220074
GO:0009712 3 GO:0009712 catechol-containing compound metabolic process GOBP 20 0.8079829 2.2433784 up 0.0029423 0.0358375 5071 220074
GO:0060249 3 GO:0060249 anatomical structure homeostasis GOBP 180 0.3488495 1.4174358 up 0.0029502 0.0358375 5052 25824 5071 25978 2185 10518 1525
GO:0070633 3 GO:0070633 transepithelial transport GOBP 8 -0.9835072 0.3739971 down 0.0030765 0.0371582 358 6558 1525
GO:0030098 3 GO:0030098 lymphocyte differentiation GOBP 124 0.3897232 1.4765720 up 0.0031568 0.0377511 6097 2185 387357
GO:0042573 3 GO:0042573 retinoic acid metabolic process GOBP 8 1.0076816 2.7392431 up 0.0031965 0.0381267
GO:0036230 3 GO:0036230 granulocyte activation GOBP 17 0.8474150 2.3336067 up 0.0033081 0.0392551 6844 6810
GO:0006694 3 GO:0006694 steroid biosynthetic process GOBP 105 -0.3948730 0.6737656 down 0.0033454 0.0395472 7555 231 6342 2224 1717 10682 7421
GO:0000083 3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle GOBP 21 0.7622360 2.1430627 up 0.0033499 0.0395472 8462
GO:0006700 3 GO:0006700 C21-steroid hormone biosynthetic process GOBP 15 -0.7806355 0.4581148 down 0.0035083 0.0408944 231 6342
GO:0019884 3 GO:0019884 antigen processing and presentation of exogenous antigen GOBP 162 0.3308002 1.3920816 up 0.0035722 0.0413266 140735 10121 163 8722 83547 3797 81930
GO:0044783 3 GO:0044783 G1 DNA damage checkpoint GOBP 75 0.4725673 1.6041071 up 0.0035830 0.0413480 8738
GO:0033540 3 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase GOBP 12 -0.8409645 0.4312943 down 0.0037631 0.0432145 6342 30
GO:0032648 3 GO:0032648 regulation of interferon-beta production GOBP 41 0.6449638 1.9059180 up 0.0037635 0.0432145 1654 10621 5971
GO:0000245 3 GO:0000245 spliceosomal complex assembly GOBP 43 0.6042156 1.8298163 up 0.0038478 0.0440729 10291
GO:0030490 3 GO:0030490 maturation of SSU-rRNA GOBP 37 0.6292867 1.8762718 up 0.0038804 0.0443360
GO:1901623 3 GO:1901623 regulation of lymphocyte chemotaxis GOBP 9 0.9667111 2.6292829 up 0.0038924 0.0443639 2185
GO:0032608 3 GO:0032608 interferon-beta production GOBP 45 0.6283920 1.8745937 up 0.0039460 0.0447536 1654 10621 5971
GO:0043370 3 GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation GOBP 14 0.8729895 2.3940573 up 0.0039741 0.0449617
GO:0042770 3 GO:0042770 signal transduction in response to DNA damage GOBP 127 0.3747130 1.4545738 up 0.0039854 0.0449800 1655 23028 10524 8738
GO:0090263 3 GO:0090263 positive regulation of canonical Wnt signaling pathway GOBP 111 0.3934885 1.4821423 up 0.0041689 0.0469356 324
GO:0009067 3 GO:0009067 aspartate family amino acid biosynthetic process GOBP 18 -0.7898210 0.4539260 down 0.0041865 0.0470193 2805 79896
GO:0071219 3 GO:0071219 cellular response to molecule of bacterial origin GOBP 73 0.4767038 1.6107562 up 0.0042301 0.0472790 92140 54623 3148 3606 3929 23729 1234
GO:0071377 3 GO:0071377 cellular response to glucagon stimulus GOBP 25 -0.6269916 0.5341965 down 0.0043496 0.0484974 109 2788 2785
GO:0019509 3 GO:0019509 L-methionine biosynthetic process from methylthioadenosine GOBP 10 -1.0071978 0.3652410 down 0.0043623 0.0485216 2805
GO:0044724 3 GO:0044724 single-organism carbohydrate catabolic process GOBP 90 -0.4011029 0.6695812 down 0.0043871 0.0486798 7167 2821 5571 957 6652 9942
GO:0090200 3 GO:0090200 positive regulation of release of cytochrome c from mitochondria GOBP 28 -0.6354326 0.5297063 down 0.0044280 0.0490158 10059 10105 26355 10018
GO:0006119 4 GO:0006119 oxidative phosphorylation GOBP 61 -1.4658082 0.2308913 down 0.0000000 0.0000000 2631 7385 7381 4697 4719 7384 4720 4715 54205 4716 509 4723 4698 400916 4710 4705 29796 4694 4725 7388 4711 4722 4717 4709 4708 4728 4706 4731 4724 4702 4707 4726 10105 1355 4695 4712 6901 4704 4714
GO:0042773 4 GO:0042773 ATP synthesis coupled electron transport GOBP 45 -1.5129922 0.2202500 down 0.0000000 0.0000000 4697 4719 4720 4715 54205 4716 4723 4698 4710 4705 29796 4694 4725 4711 4722 4717 4709 4708 4728 4706 4731 4724 4702 4707 4726 1355 4695 4712 6901 4704 4714
GO:0042775 4 GO:0042775 mitochondrial ATP synthesis coupled electron transport GOBP 45 -1.5129922 0.2202500 down 0.0000000 0.0000000 4697 4719 4720 4715 54205 4716 4723 4698 4710 4705 29796 4694 4725 4711 4722 4717 4709 4708 4728 4706 4731 4724 4702 4707 4726 1355 4695 4712 6901 4704 4714
GO:0006120 4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone GOBP 39 -1.5141325 0.2199989 down 0.0000000 0.0000000 4697 4719 4720 4715 4716 4723 4698 4710 4705 4694 4725 4711 4722 4717 4709 4708 4728 4706 4731 4724 4702 4707 4726 4695 4712 4704 4714
GO:0018193 5 GO:0018193 peptidyl-amino acid modification GOBP 889 0.2049660 1.2274833 up 0.0001555 0.0034987 23171 80218 10935 9261 9334 7423 1454 102800317 493 10105 5585 23408 64324 11328 84447 2321 8440 10524 23410 1801 28989 285381 9575 90 3480 340481 10283 22823 79918 7862 51611 5154 1636 54556 2185 2324 9654 2081 2066 79796 613 3606 79053 1942 6839 196541 5470
GO:1903052 6 GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process GOBP 131 0.4252414 1.5299597 up 0.0006961 0.0120338 1454 102800317 8078 5071 51529 9992
GO:1903364 6 GO:1903364 positive regulation of cellular protein catabolic process GOBP 133 0.4055913 1.5001893 up 0.0011648 0.0179829 1454 102800317 8078 5071 51529 9992
GO:0045732 6 GO:0045732 positive regulation of protein catabolic process GOBP 186 0.3493307 1.4181180 up 0.0012707 0.0190440 4947 1454 102800317 8078 2308 324 5071 51529 9992
GO:0031331 6 GO:0031331 positive regulation of cellular catabolic process GOBP 235 0.2980629 1.3472465 up 0.0022584 0.0300058 92140 1454 102800317 8078 2308 6832 5071 51529 957 9992
GO:0009896 6 GO:0009896 positive regulation of catabolic process GOBP 274 0.2692674 1.3090052 up 0.0032993 0.0392520 4947 92140 1454 102800317 8078 2308 6832 324 5071 51529 957 9992
GO:0043207 7 GO:0043207 response to external biotic stimulus GOBP 389 0.2387157 1.2696176 up 0.0029376 0.0358375 10935 1654 9261 163 92140 22948 708 10542 54623 58487 3727 3148 11019 26146 255520 3606 3929 4283 8347 23729 1234 6355 1525
GO:0051707 7 GO:0051707 response to other organism GOBP 389 0.2387157 1.2696176 up 0.0029376 0.0358375 10935 1654 9261 163 92140 22948 708 10542 54623 58487 3727 3148 11019 26146 255520 3606 3929 4283 8347 23729 1234 6355 1525
GO:0009617 7 GO:0009617 response to bacterium GOBP 192 0.3303940 1.3915162 up 0.0031323 0.0375549 10935 9261 92140 54623 3727 3148 11019 3606 3929 4283 8347 23729 1234
GO:0009607 7 GO:0009607 response to biotic stimulus GOBP 410 0.2228444 1.2496261 up 0.0045007 0.0497018 10935 1654 9261 163 92140 22948 708 10542 54623 58487 3727 3148 11019 26146 255520 3606 3929 4283 8347 23729 1234 6355 1525
GO:0016337 8 GO:0016337 single organismal cell-cell adhesion GOBP 471 0.2494545 1.2833252 up 0.0007888 0.0130967 5588 6097 80139 30968 79872 1952 8440 23560 10808 3606 22829 387357 151888 5314 1525
GO:0098602 8 GO:0098602 single organism cell adhesion GOBP 513 0.2165194 1.2417472 up 0.0024969 0.0326513 5588 6097 80139 708 30968 79872 1952 8440 23560 10808 3606 1942 22829 387357 151888 5314 1525
GO:0034728 9 GO:0034728 nucleosome organization GOBP 97 0.5462383 1.7267453 up 0.0002474 0.0051444 54623 6599 80152 3148 11339 8347
GO:0071103 9 GO:0071103 DNA conformation change GOBP 174 0.4156161 1.5153041 up 0.0003955 0.0076394 1654 9131 54623 6832 80152 3148 6732 5965 51203 11339 8347
GO:0071824 9 GO:0071824 protein-DNA complex subunit organization GOBP 124 0.4735467 1.6056790 up 0.0004254 0.0080479 54623 6599 80152 3148 11339 8347
GO:0006338 9 GO:0006338 chromatin remodeling GOBP 132 0.4478352 1.5649207 up 0.0005110 0.0093984 9878 6599 80152 54108 3148 2099 11339
GO:0006333 9 GO:0006333 chromatin assembly or disassembly GOBP 109 0.4562311 1.5781150 up 0.0013473 0.0198694 54623 6599 80152 3148 11339 8347
GO:0006323 9 GO:0006323 DNA packaging GOBP 114 0.4128427 1.5111073 up 0.0035328 0.0410764 9131 54623 80152 3148 6732 51203 11339 8347
GO:0009063 10 GO:0009063 cellular amino acid catabolic process GOBP 101 -0.9387243 0.3911265 down 0.0000000 0.0000000 2806 4967 2805 1738 1743 36 11112 4329 493 10295 2746 8659 5092 587 6470 2639 501 7263 594 125061 89874 51268
GO:0006520 10 GO:0006520 cellular amino acid metabolic process GOBP 388 -0.5646437 0.5685627 down 0.0000000 0.0000000 1158 1160 2806 4967 2805 1738 5859 4947 1743 36 4677 11112 51520 4522 4329 493 51582 10295 2746 376497 81579 8659 80222 5092 1152 5188 2875 2730 587 6470 6611 10797 79731 2639 501 255189 64122 7263 594 125061 79896 89874 51268
GO:1901605 10 GO:1901605 alpha-amino acid metabolic process GOBP 197 -0.7147888 0.4892954 down 0.0000000 0.0000000 1158 1160 2806 4967 2805 1738 1743 11112 4522 4329 493 2746 376497 81579 8659 5092 1152 2730 6470 6611 10797 2639 501 255189 125061 79896 89874 51268
GO:1901606 10 GO:1901606 alpha-amino acid catabolic process GOBP 68 -0.9416996 0.3899645 down 0.0000000 0.0000000 2806 4967 2805 1738 1743 11112 4329 493 2746 8659 5092 6470 2639 501 125061 89874 51268
GO:1901565 10 GO:1901565 organonitrogen compound catabolic process GOBP 286 -0.4861805 0.6149708 down 0.0000000 0.0000000 2806 4967 2805 1738 1743 36 11112 4329 493 10295 5141 2746 131870 8659 5092 587 6470 8879 2639 66005 501 51071 7263 5168 594 1636 125061 4595 56953 220074 283927 89874 51268 10675 11081
GO:0044265 11 GO:0044265 cellular macromolecule catabolic process GOBP 917 0.2047923 1.2272701 up 0.0001760 0.0038683 7812 6175 54205 1508 3836 267 11124 1454 102800317 23405 9131 8078 115752 131870 84937 84447 6832 324 5071 51529 10524 10193 2021 6049 3148 9575 26235 92667 128387 6477 2185 84132 2081 57531 11277 2272 1973 10040 9992
GO:0051603 11 GO:0051603 proteolysis involved in cellular protein catabolic process GOBP 555 0.2384039 1.2692217 up 0.0005138 0.0094114 1508 267 11124 1454 102800317 8078 84937 84447 324 5071 51529 10524 10193 6049 9575 26235 6477 2185 84132 57531 2272 10040 9992
GO:0044257 11 GO:0044257 cellular protein catabolic process GOBP 575 0.2326332 1.2619186 up 0.0005627 0.0102660 1508 267 11124 1454 102800317 8078 84937 84447 324 5071 51529 10524 10193 6049 9575 26235 6477 2185 84132 57531 2272 10040 9992
GO:0006511 11 GO:0006511 ubiquitin-dependent protein catabolic process GOBP 493 0.2441692 1.2765602 up 0.0007414 0.0125387 267 11124 1454 102800317 8078 84937 84447 324 5071 51529 10524 6049 9575 26235 6477 2185 84132 57531 2272 10040
GO:0043632 11 GO:0043632 modification-dependent macromolecule catabolic process GOBP 506 0.2408085 1.2722774 up 0.0007416 0.0125387 267 11124 1454 102800317 8078 84937 84447 324 5071 51529 10524 6049 9575 26235 6477 2185 84132 57531 2272 10040
GO:0019941 11 GO:0019941 modification-dependent protein catabolic process GOBP 500 0.2379905 1.2686972 up 0.0009282 0.0149533 267 11124 1454 102800317 8078 84937 84447 324 5071 51529 10524 6049 9575 26235 6477 2185 84132 57531 2272 10040
GO:0030163 11 GO:0030163 protein catabolic process GOBP 676 0.1937784 1.2138272 up 0.0019568 0.0268831 4947 1508 5774 267 11124 1454 102800317 8078 51582 2308 84937 84447 324 5071 51529 10524 10193 6049 9575 26235 6477 1636 2185 84132 57531 2272 10040 9992
GO:0051169 12 GO:0051169 nuclear transport GOBP 320 0.3375073 1.4014498 up 0.0000767 0.0019657 387 3836 6427 11124 7248 25937 2066 10636 5936
GO:0006913 12 GO:0006913 nucleocytoplasmic transport GOBP 317 0.3304500 1.3915943 up 0.0001180 0.0028071 387 3836 6427 11124 7248 25937 2066 10636 5936
GO:1903651 12 GO:1903651 positive regulation of cytoplasmic transport GOBP 165 0.3615306 1.4355249 up 0.0013451 0.0198694 387 3836 2181 79753 2066 4283 90506
GO:1903649 12 GO:1903649 regulation of cytoplasmic transport GOBP 308 0.2714635 1.3118830 up 0.0019860 0.0269689 10345 387 3836 11124 2181 5071 25937 2185 79753 2066 4283 5936 90506
GO:0051170 12 GO:0051170 nuclear import GOBP 173 0.3306399 1.3918585 up 0.0033886 0.0399020 387 3836 11124 25937 2066
GO:0045944 13 GO:0045944 positive regulation of transcription from RNA polymerase II promoter GOBP 653 0.2331939 1.2626262 up 0.0002418 0.0050497 7555 4782 1655 1654 6495 10135 4781 7376 23028 54623 2308 4855 5071 8440 10524 3727 1874 182 4331 466 3148 9575 4899 90 1488 25937 94 9645 6018 22823 84836 8178 2099 10001 5077 5971 55897 6666 7421
GO:0006986 14 GO:0006986 response to unfolded protein GOBP 135 0.4533711 1.5736080 up 0.0003437 0.0068099 3306 3068 267 9114 64061 84447 5071 10808 10018 578 2081 22824
GO:0034620 14 GO:0034620 cellular response to unfolded protein GOBP 107 0.4750067 1.6080250 up 0.0007511 0.0126544 3068 267 9114 64061 84447 5071 10018 578 2081
GO:0035966 14 GO:0035966 response to topologically incorrect protein GOBP 143 0.4161275 1.5160792 up 0.0007692 0.0128653 3306 3068 267 9114 64061 84447 5071 10808 10018 578 2081 22824
GO:0030968 14 GO:0030968 endoplasmic reticulum unfolded protein response GOBP 104 0.4590917 1.5826358 up 0.0013993 0.0204411 3068 267 9114 64061 84447 10018 578 2081
GO:0035967 14 GO:0035967 cellular response to topologically incorrect protein GOBP 114 0.4321320 1.5405385 up 0.0016834 0.0236910 3068 267 9114 64061 84447 5071 10018 578 2081
GO:0034976 14 GO:0034976 response to endoplasmic reticulum stress GOBP 191 0.3543108 1.4251981 up 0.0026867 0.0343542 488 3068 267 9114 9131 64061 84447 5071 8440 10018 578 2081 79094
GO:0034097 15 GO:0034097 response to cytokine GOBP 547 0.2561433 1.2919379 up 0.0001961 0.0042308 9261 3836 9093 79602 5245 7376 204851 5071 3727 51447 5355 7706 2185 4283 8835 1973 5971 23729 1234 3664 2829
GO:0016032 15 GO:0016032 viral process GOBP 530 0.2315446 1.2605456 up 0.0005748 0.0104344 291 6175 1654 3836 9218 163 5071 25978 6993 7706 4331 6732 1488 8178 222537 1234
GO:0019221 15 GO:0019221 cytokine-mediated signaling pathway GOBP 373 0.2616875 1.2991205 up 0.0010890 0.0170403 3836 9093 79602 7376 204851 5071 51447 5355 7706 2185 4283 8835 1973 1234 3664 2829
GO:0044764 15 GO:0044764 multi-organism cellular process GOBP 547 0.2159433 1.2410321 up 0.0011527 0.0178552 291 6175 1654 3836 9218 163 708 5071 25978 6993 7706 4331 6732 1488 8178 222537 1234
GO:0044403 15 GO:0044403 symbiosis, encompassing mutualism through parasitism GOBP 571 0.2101868 1.2339085 up 0.0012208 0.0185368 291 6175 1654 3836 9218 358 163 535 9114 5071 25978 6993 7706 4331 6732 1488 8178 222537 1234
GO:0044419 15 GO:0044419 interspecies interaction between organisms GOBP 571 0.2101868 1.2339085 up 0.0012208 0.0185368 291 6175 1654 3836 9218 358 163 535 9114 5071 25978 6993 7706 4331 6732 1488 8178 222537 1234
GO:0071345 15 GO:0071345 cellular response to cytokine stimulus GOBP 470 0.2164378 1.2416458 up 0.0030831 0.0371582 3836 9093 79602 5245 7376 204851 5071 51447 5355 7706 2185 4283 8835 1973 23729 1234 3664 2829
GO:0050776 16 GO:0050776 regulation of immune response GOBP 717 0.2400646 1.2713313 up 0.0000919 0.0022810 5588 9261 1508 9093 708 30968 7376 2308 6810 466 5608 4773 5154 10621 2066 3929 9542 10225 387357 1525
GO:0002764 16 GO:0002764 immune response-regulating signaling pathway GOBP 465 0.2475243 1.2808504 up 0.0007581 0.0127255 5588 9261 1508 708 30968 2308 466 5608 4773 5154 2066 3929 9542 387357
GO:0050778 16 GO:0050778 positive regulation of immune response GOBP 494 0.2318132 1.2608841 up 0.0016113 0.0229564 5588 9261 1508 708 30968 6810 466 5608 4773 10621 3929 387357
GO:0023014 16 GO:0023014 signal transduction by phosphorylation GOBP 580 0.2045802 1.2270098 up 0.0029485 0.0358375 9261 9459 7164 7423 5585 2308 8428 2321 5071 10193 466 28988 3480 84231 4055 5608 5154 2185 2324 2066 2122 3606 10636 5936 6288 1234 5470 5314 2785
GO:0002768 16 GO:0002768 immune response-regulating cell surface receptor signaling pathway GOBP 321 0.2511619 1.2855182 up 0.0034499 0.0403443 5588 30968 2308 4773 5154 2066 9542 387357
GO:0000165 16 GO:0000165 MAPK cascade GOBP 558 0.1999409 1.2213306 up 0.0041996 0.0470523 9261 9459 7164 7423 5585 2308 2321 5071 10193 466 28988 3480 84231 4055 5608 5154 2185 2324 2066 2122 3606 10636 5936 6288 1234 5470 5314 2785
GO:0007159 17 GO:0007159 leukocyte cell-cell adhesion GOBP 297 0.3937872 1.4825850 up 0.0000190 0.0005900 5588 6097 30968 8440 10808 3606 387357 151888 1525
GO:0070486 17 GO:0070486 leukocyte aggregation GOBP 268 0.3770137 1.4579243 up 0.0000990 0.0024309 5588 6097 30968 8440 10808 3606 387357 151888 1525
GO:0071593 17 GO:0071593 lymphocyte aggregation GOBP 262 0.3745796 1.4543798 up 0.0001362 0.0031587 5588 6097 30968 8440 10808 3606 387357 151888 1525
GO:0042110 17 GO:0042110 T cell activation GOBP 261 0.3729628 1.4520303 up 0.0001512 0.0034377 5588 6097 30968 8440 10808 3606 387357 151888 1525
GO:0070489 17 GO:0070489 T cell aggregation GOBP 261 0.3729628 1.4520303 up 0.0001512 0.0034377 5588 6097 30968 8440 10808 3606 387357 151888 1525
GO:0034109 17 GO:0034109 homotypic cell-cell adhesion GOBP 317 0.3374807 1.4014125 up 0.0001584 0.0034987 5588 6097 80139 30968 8440 10808 3606 387357 151888 1525
GO:0050863 17 GO:0050863 regulation of T cell activation GOBP 181 0.4232309 1.5268868 up 0.0002085 0.0044143 5588 8440 10808 3606 151888
GO:1903037 17 GO:1903037 regulation of leukocyte cell-cell adhesion GOBP 187 0.4117534 1.5094621 up 0.0002549 0.0052523 5588 8440 10808 3606 151888
GO:0022409 17 GO:0022409 positive regulation of cell-cell adhesion GOBP 154 0.4344942 1.5441818 up 0.0002993 0.0060859 5588 8440 10808 3606 151888
GO:0050870 17 GO:0050870 positive regulation of T cell activation GOBP 136 0.4541981 1.5749100 up 0.0003533 0.0069676 5588 8440 10808 3606 151888
GO:1903039 17 GO:1903039 positive regulation of leukocyte cell-cell adhesion GOBP 138 0.4500291 1.5683578 up 0.0003638 0.0071149 5588 8440 10808 3606 151888
GO:0046649 17 GO:0046649 lymphocyte activation GOBP 362 0.2972848 1.3461987 up 0.0004601 0.0086432 5588 6097 30968 8440 10808 4773 2185 3606 57823 387357 151888 1525
GO:0034112 17 GO:0034112 positive regulation of homotypic cell-cell adhesion GOBP 139 0.4387443 1.5507588 up 0.0004994 0.0092581 5588 8440 10808 3606 151888
GO:0051249 17 GO:0051249 regulation of lymphocyte activation GOBP 234 0.3546127 1.4256283 up 0.0005067 0.0093558 5588 8440 10808 4773 3606 151888
GO:0034110 17 GO:0034110 regulation of homotypic cell-cell adhesion GOBP 193 0.3796215 1.4617311 up 0.0006844 0.0118774 5588 80139 8440 10808 3606 151888
GO:0051251 17 GO:0051251 positive regulation of lymphocyte activation GOBP 168 0.3761705 1.4566954 up 0.0012442 0.0187073 5588 8440 10808 4773 3606 151888
GO:0046634 17 GO:0046634 regulation of alpha-beta T cell activation GOBP 32 0.6979786 2.0096863 up 0.0017870 0.0248451 5588 10808 3606
GO:0045785 17 GO:0045785 positive regulation of cell adhesion GOBP 226 0.3138372 1.3686669 up 0.0019700 0.0269689 5588 7248 708 8440 10808 6810 2185 3606 6288 151888
GO:0072329 18 GO:0072329 monocarboxylic acid catabolic process GOBP 85 -0.8528570 0.4261955 down 0.0000000 0.0000000 2806 34 1892 10455 6342 1666 5096 1632 8659 30 84693 5095 1962
GO:0006635 18 GO:0006635 fatty acid beta-oxidation GOBP 59 -0.9566651 0.3841719 down 0.0000000 0.0000000 34 1892 6342 1666 5096 1632 30 84693 5095 1962
GO:0009062 18 GO:0009062 fatty acid catabolic process GOBP 75 -0.8629688 0.4219077 down 0.0000000 0.0000000 34 1892 10455 6342 1666 5096 1632 30 84693 5095 1962
GO:0019395 18 GO:0019395 fatty acid oxidation GOBP 78 -0.8402722 0.4315930 down 0.0000000 0.0000000 5166 34 1892 6342 1666 79602 5096 1632 30 84693 5095 1962 116285
GO:0034440 18 GO:0034440 lipid oxidation GOBP 80 -0.8247108 0.4383617 down 0.0000000 0.0000000 5166 34 1892 6342 1666 79602 5096 1632 30 84693 5095 1962 116285
GO:0044242 18 GO:0044242 cellular lipid catabolic process GOBP 133 -0.5656915 0.5679672 down 0.0000005 0.0000206 34 1892 10455 6342 1666 5096 1632 30 8879 84693 5095 5168 1962
GO:0030258 18 GO:0030258 lipid modification GOBP 118 -0.5687333 0.5662422 down 0.0000018 0.0000694 5166 34 1892 6342 1666 79602 5096 1632 30 51447 2053 84693 5095 1962 116285
GO:0016042 18 GO:0016042 lipid catabolic process GOBP 157 -0.4961872 0.6088477 down 0.0000038 0.0001395 34 1892 10455 6342 1666 5096 1632 30 8879 84693 5095 8578 5168 1962
GO:0001569 19 GO:0001569 patterning of blood vessels GOBP 12 -0.9901922 0.3715053 down 0.0001001 0.0024455 4855 54567
GO:0001974 19 GO:0001974 blood vessel remodeling GOBP 15 -0.9262093 0.3960522 down 0.0001579 0.0034987 64114 93 94 1636 2324 54567
GO:1903670 19 GO:1903670 regulation of sprouting angiogenesis GOBP 18 -0.8335360 0.4345101 down 0.0004029 0.0077162 54567
GO:0060840 19 GO:0060840 artery development GOBP 29 -0.7026709 0.4952607 down 0.0004223 0.0080215 182 93 94 54567
GO:0061384 19 GO:0061384 heart trabecula morphogenesis GOBP 10 -0.9532177 0.3854986 down 0.0007955 0.0131153 54567
GO:0003208 19 GO:0003208 cardiac ventricle morphogenesis GOBP 36 -0.6188888 0.5385425 down 0.0008041 0.0131153 182 54567 55897
GO:0002040 19 GO:0002040 sprouting angiogenesis GOBP 53 -0.5347391 0.5858221 down 0.0010184 0.0161541 94 2185 2324 54567
GO:0061314 19 GO:0061314 Notch signaling involved in heart development GOBP 10 -0.9509361 0.3863792 down 0.0015030 0.0216801 182 54567
GO:0010596 19 GO:0010596 negative regulation of endothelial cell migration GOBP 29 -0.6667289 0.5133852 down 0.0015713 0.0225249 94 54567 6781
GO:0035909 19 GO:0035909 aorta morphogenesis GOBP 13 -0.8410809 0.4312441 down 0.0016575 0.0234694 182 54567
GO:0035904 19 GO:0035904 aorta development GOBP 14 -0.8116586 0.4441208 down 0.0019846 0.0269689 182 54567
GO:0043537 19 GO:0043537 negative regulation of blood vessel endothelial cell migration GOBP 19 -0.7458355 0.4743378 down 0.0019960 0.0270189 94 54567
GO:0007389 19 GO:0007389 pattern specification process GOBP 141 -0.3501762 0.7045639 down 0.0020027 0.0270303 6495 4855 1952 93 90 9645 22823 2066 5727 54567 3207 57216 55897 57453 6781
GO:0061298 19 GO:0061298 retina vasculature development in camera-type eye GOBP 10 -0.8980423 0.4073664 down 0.0022354 0.0298229 93 94
GO:0030855 19 GO:0030855 epithelial cell differentiation GOBP 219 -0.2813631 0.7547543 down 0.0022621 0.0300058 7416 6495 1508 84162 373156 80139 4781 4855 1874 182 9575 93 90 94 64122 7263 2066 7481 220074 55897 7421 6781 3664 5800
GO:0003013 19 GO:0003013 circulatory system process GOBP 283 -0.2715564 0.7621923 down 0.0025349 0.0329612 488 10345 6648 23171 493 6330 6901 2730 94 2053 6327 1636 54567 6781 5800 9992
GO:0008015 19 GO:0008015 blood circulation GOBP 281 -0.2716195 0.7621442 down 0.0025852 0.0334265 488 10345 6648 23171 493 6330 6901 2730 94 2053 6327 1636 54567 6781 5800 9992
GO:0060841 19 GO:0060841 venous blood vessel development GOBP 9 -0.9168761 0.3997659 down 0.0027168 0.0346430 93 94
GO:0051216 19 GO:0051216 cartilage development GOBP 64 -0.4742558 0.6223480 down 0.0028201 0.0354707 4781 94 649 1302 7481 3207 6781
GO:0090049 19 GO:0090049 regulation of cell migration involved in sprouting angiogenesis GOBP 16 -0.7739643 0.4611812 down 0.0028618 0.0355696 54567
GO:0001936 19 GO:0001936 regulation of endothelial cell proliferation GOBP 73 -0.4388020 0.6448084 down 0.0030417 0.0368511 498 7423 3148 94 2324 54567
GO:0021517 19 GO:0021517 ventral spinal cord development GOBP 5 -1.0815900 0.3390560 down 0.0034523 0.0403443 54567
GO:0044283 20 GO:0044283 small molecule biosynthetic process GOBP 334 -0.3542602 0.7016923 down 0.0000074 0.0002421 7555 5166 2806 2805 34 5565 8803 6342 117283 4706 2686 493 2181 2746 7376 376497 51004 2224 4258 2875 6470 622 11019 51805 55217 57107 2185 1717 22949 79896 10682 7421 10675
GO:0016053 20 GO:0016053 organic acid biosynthetic process GOBP 198 -0.4014203 0.6693687 down 0.0000530 0.0014656 5166 2806 2805 34 5565 8803 6342 4706 2686 493 2746 7376 376497 4258 2875 6470 11019 55217 22949 79896 10675
GO:0046394 20 GO:0046394 carboxylic acid biosynthetic process GOBP 198 -0.4014203 0.6693687 down 0.0000530 0.0014656 5166 2806 2805 34 5565 8803 6342 4706 2686 493 2746 7376 376497 4258 2875 6470 11019 55217 22949 79896 10675
GO:0008610 20 GO:0008610 lipid biosynthetic process GOBP 544 -0.2010625 0.8178613 down 0.0029110 0.0358375 7555 5166 23171 5565 231 9218 6342 4706 2686 161247 2181 7376 376497 81579 2224 54675 6901 4258 151742 56261 11019 8879 5833 55326 255189 57107 5154 1717 22949 10682 7421
GO:0000278 21 GO:0000278 mitotic cell cycle GOBP 855 0.2933407 1.3408996 up 0.0000001 0.0000065 8615 80218 51119 8451 387 2029 1654 5774 10121 7164 1454 102800317 10383 26003 51143 324 25978 51529 1874 6993 80152 5884 4331 23595 26524 138151 90 415116 4173 8462 79648 51203 1978 4171 84515 55145 8738 1031 5292 22981 79858 10040 81930 221150 29935
GO:1903047 21 GO:1903047 mitotic cell cycle process GOBP 679 0.3096650 1.3629685 up 0.0000004 0.0000155 80218 51119 8451 387 2029 1654 10121 7164 1454 102800317 10383 51143 324 25978 51529 6993 5884 4331 23595 26524 138151 90 4173 8462 51203 1978 4171 84515 8738 1031 5292 22981 79858 10040 81930 221150 29935
GO:0044770 21 GO:0044770 cell cycle phase transition GOBP 402 0.2907158 1.3373844 up 0.0001297 0.0030240 8451 2029 1654 10121 7164 1454 102800317 493 10383 324 51529 4331 23595 26524 138151 90 4173 8462 1978 4171 84515 8738 1031 5292 22981 29935
GO:0044772 21 GO:0044772 mitotic cell cycle phase transition GOBP 387 0.2899962 1.3364225 up 0.0001788 0.0038922 8451 2029 1654 10121 7164 1454 102800317 10383 324 51529 4331 23595 26524 138151 90 4173 8462 1978 4171 84515 8738 1031 5292 22981 29935
GO:0000082 21 GO:0000082 G1/S transition of mitotic cell cycle GOBP 210 0.3445724 1.4113863 up 0.0007164 0.0122942 8451 1654 4331 23595 26524 138151 90 4173 8462 1978 4171 84515 8738 1031 5292 29935
GO:0044843 21 GO:0044843 cell cycle G1/S phase transition GOBP 215 0.3383422 1.4026205 up 0.0008016 0.0131153 8451 1654 493 4331 23595 26524 138151 90 4173 8462 1978 4171 84515 8738 1031 5292 29935
GO:0001775 22 GO:0001775 cell activation GOBP 659 0.2711335 1.3114501 up 0.0000209 0.0006435 387 7450 5588 6097 7423 6844 30968 8440 10808 6810 4773 5154 2185 3606 3929 7424 6288 57823 23729 387357 151888 1525
GO:0002684 22 GO:0002684 positive regulation of immune system process GOBP 692 0.2576162 1.2938421 up 0.0000504 0.0014185 5588 9261 1508 7423 708 30968 8440 10808 6810 466 3148 5608 4773 10621 2185 3606 3929 4283 7424 387357 151888
GO:0045321 22 GO:0045321 leukocyte activation GOBP 431 0.3036347 1.3547741 up 0.0000965 0.0023830 5588 6097 6844 30968 8440 10808 6810 4773 2185 3606 3929 57823 23729 387357 151888 1525
GO:0002696 22 GO:0002696 positive regulation of leukocyte activation GOBP 182 0.4113600 1.5088685 up 0.0002079 0.0044143 5588 8440 10808 6810 4773 3606 3929 151888
GO:0050867 22 GO:0050867 positive regulation of cell activation GOBP 189 0.3950184 1.4844115 up 0.0002882 0.0058856 5588 8440 10808 6810 4773 3606 3929 151888
GO:0050865 22 GO:0050865 regulation of cell activation GOBP 284 0.3243079 1.3830730 up 0.0004606 0.0086432 5588 8440 10808 6810 4773 5154 3606 3929 23729 151888
GO:0002694 22 GO:0002694 regulation of leukocyte activation GOBP 265 0.3237925 1.3823605 up 0.0007760 0.0129321 5588 8440 10808 6810 4773 3606 3929 23729 151888
GO:0009150 23 GO:0009150 purine ribonucleotide metabolic process GOBP 274 -0.8101726 0.4447813 down 0.0000000 0.0000000 506 498 122622 2631 7385 7381 4697 4719 7384 517 4720 4715 54205 4716 509 4723 522 518 515 4698 400916 10476 4710 4705 29796 10632 4694 516 4725 7388 358 521 4711 514 4722 4717 4709 4708 4728 4706 4731 535 4724 4702 539 4707 4726 10105 30968 5141 131870 1355 9551 4695 4712 6901 957 4704 84693 4714 283927 4283 117 2696
GO:0009259 23 GO:0009259 ribonucleotide metabolic process GOBP 279 -0.7925233 0.4527011 down 0.0000000 0.0000000 506 498 122622 2631 7385 7381 4697 4719 7384 517 4720 4715 54205 4716 509 4723 522 518 515 4698 400916 10476 4710 4705 29796 10632 4694 516 4725 7388 358 521 4711 514 4722 4717 4709 4708 4728 4706 4731 535 4724 4702 539 4707 4726 10105 30968 5141 131870 1355 9551 4695 4712 6901 957 4704 84693 4714 283927 4283 117 2696
GO:0019693 23 GO:0019693 ribose phosphate metabolic process GOBP 297 -0.7727759 0.4617296 down 0.0000000 0.0000000 506 498 122622 2631 7385 7381 4697 4719 7384 517 4720 4715 54205 4716 509 4723 522 518 515 4698 400916 10476 4710 4705 29796 10632 4694 516 4725 7388 358 521 4711 514 4722 4717 4709 4708 4728 4706 4731 535 4724 4702 539 4707 4726 10105 30968 5141 131870 1355 9551 4695 4712 6901 957 4704 84693 4714 283927 4283 117 23729 2696
GO:0006163 23 GO:0006163 purine nucleotide metabolic process GOBP 305 -0.7577696 0.4687107 down 0.0000000 0.0000000 506 498 122622 2631 7385 7381 4697 4719 7384 517 4720 4715 54205 4716 509 4723 522 518 515 4698 400916 10476 4710 4705 29796 10632 4694 516 4725 7388 358 521 4711 514 4722 4717 4709 4708 4728 4706 4731 535 4724 4702 539 4707 4726 10105 30968 5141 131870 1355 9551 4695 4712 6901 957 4704 84693 4714 4595 2272 283927 4283 117 2696
GO:0006753 23 GO:0006753 nucleoside phosphate metabolic process GOBP 460 -0.6537024 0.5201165 down 0.0000000 0.0000000 506 498 122622 2631 7385 7381 4697 4719 7384 517 4720 4715 54205 23171 4716 509 4723 522 518 515 4698 400916 10476 4710 4705 29796 10632 4694 516 4725 7388 358 3615 521 4711 514 25824 4722 4717 10135 4709 4708 4728 4706 4731 535 4724 4702 539 4707 4726 10105 30968 5141 131870 1355 9551 4695 4712 6901 957 4704 4354 84693 132 79077 349565 4714 4595 56953 2272 283927 4283 2762 117 23729 2696 122481
GO:0055086 23 GO:0055086 nucleobase-containing small molecule metabolic process GOBP 549 -0.6166356 0.5397574 down 0.0000000 0.0000000 506 498 122622 2631 7385 7381 4697 4719 7384 517 4720 4715 54205 23171 4716 509 4723 522 518 515 4698 400916 10476 4710 4705 29796 10632 4694 516 4725 7388 358 3615 521 4711 514 25824 4722 4717 10135 4709 4708 4728 4706 4731 535 4724 4702 539 4707 4329 4726 10105 30968 5141 131870 1355 9551 27430 4695 4712 6901 2745 957 4704 6470 4354 84693 132 79077 349565 51071 4714 64172 4595 1723 56953 112858 2272 283927 4283 2762 117 23729 8382 2696 122481
GO:0009117 23 GO:0009117 nucleotide metabolic process GOBP 438 -0.6503922 0.5218411 down 0.0000000 0.0000000 506 498 122622 2631 7385 7381 4697 4719 7384 517 4720 4715 54205 23171 4716 509 4723 522 518 515 4698 400916 10476 4710 4705 29796 10632 4694 516 4725 7388 358 521 4711 514 25824 4722 4717 10135 4709 4708 4728 4706 4731 535 4724 4702 539 4707 4726 10105 30968 5141 131870 1355 9551 4695 4712 6901 957 4704 4354 84693 349565 4714 4595 56953 2272 283927 4283 2762 117 23729 2696 122481
GO:0072521 23 GO:0072521 purine-containing compound metabolic process GOBP 357 -0.6971702 0.4979925 down 0.0000000 0.0000000 506 498 122622 2631 7385 7381 4697 4719 7384 517 4720 4715 54205 4716 509 4723 522 518 515 4698 400916 10476 4710 4705 29796 10632 4694 516 4725 7388 358 3615 521 4711 514 4722 4717 4709 4708 4728 4706 4731 535 4724 4702 539 4707 4726 10105 30968 5141 131870 1355 9551 27430 4695 4712 6901 957 4704 6470 84693 132 4714 64172 4595 112858 2272 283927 4283 220963 117 2696
GO:0019637 23 GO:0019637 organophosphate metabolic process GOBP 850 -0.4627577 0.6295451 down 0.0000000 0.0000000 506 498 122622 2631 7385 7381 4697 4719 7384 517 4720 4715 54205 23171 4716 509 4723 522 518 515 4698 400916 10476 4710 4705 29796 10632 4694 516 4725 7388 358 3615 521 4711 514 25824 4722 4717 6342 10135 4709 4708 4728 117283 4706 4731 535 4724 4702 161247 539 4707 4726 10105 30968 5141 2181 376497 131870 1355 9551 81579 4695 4712 2321 54675 51447 6901 957 4704 4337 56261 4354 92579 5833 55326 84693 132 79077 349565 255189 5154 5168 4714 2185 4595 2066 80271 56953 2272 283927 9562 4283 2762 117 23729 2696 122481
GO:0006790 24 GO:0006790 sulfur compound metabolic process GOBP 322 -0.3641006 0.6948213 down 0.0000081 0.0002608 5166 2805 5164 1738 5160 8803 8801 5162 1737 25828 9334 2686 54704 2948 5096 27430 4258 2730 26873 6611 11019 9645 84693 5095 79017 51363 9469 7263 641371 283927 222537 8534 51268 10675 11081 89792
GO:0044272 24 GO:0044272 sulfur compound biosynthetic process GOBP 164 -0.3899465 0.6770931 down 0.0003331 0.0066275 5166 2805 5164 1738 5160 5162 1737 9334 54704 2948 27430 4258 2730 26873 11019 79017 51363 9469 222537 8534 10675 11081
GO:0044282 25 GO:0044282 small molecule catabolic process GOBP 226 -0.8428214 0.4304942 down 0.0000000 0.0000000 2806 4967 2805 34 1738 1743 1892 36 10455 6342 11112 1666 4329 493 10295 5096 2746 131870 1632 8659 5092 30 587 6470 622 84693 2639 5095 501 8578 7263 5168 594 125061 6652 1962 89874 51268 57834
GO:0016054 25 GO:0016054 organic acid catabolic process GOBP 189 -0.8962642 0.4080913 down 0.0000000 0.0000000 2806 4967 2805 34 1738 1743 1892 36 10455 6342 11112 1666 4329 493 10295 5096 2746 1632 8659 5092 30 587 6470 84693 2639 5095 501 7263 594 125061 1962 89874 51268
GO:0046395 25 GO:0046395 carboxylic acid catabolic process GOBP 189 -0.8962642 0.4080913 down 0.0000000 0.0000000 2806 4967 2805 34 1738 1743 1892 36 10455 6342 11112 1666 4329 493 10295 5096 2746 1632 8659 5092 30 587 6470 84693 2639 5095 501 7263 594 125061 1962 89874 51268
GO:0044712 25 GO:0044712 single-organism catabolic process GOBP 867 -0.3807319 0.6833610 down 0.0000000 0.0000000 7167 7416 2806 4967 4190 2805 2821 34 4715 7001 1738 10935 1743 1508 5052 1892 36 10455 25824 6342 11112 1351 5571 10059 1666 55173 4329 493 10295 5096 5141 2746 131870 1632 8659 5092 324 30 5071 51529 51116 957 6507 587 6470 622 8879 2053 84693 2639 79077 5095 501 8578 9469 51071 7263 5168 594 1636 125061 4595 2081 80271 1302 56953 137902 55172 283927 6652 1962 11178 89874 202374 9942 51268 10675 11081 57834
GO:0010498 26 GO:0010498 proteasomal protein catabolic process GOBP 382 0.3396027 1.4043896 up 0.0000187 0.0005845 267 11124 1454 102800317 8078 84937 84447 324 5071 51529 10524 10193 9575 6477 84132 2272 9992
GO:0043161 26 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process GOBP 355 0.3238728 1.3824714 up 0.0000718 0.0018715 267 11124 1454 102800317 8078 84937 84447 324 5071 51529 10524 9575 6477 84132 2272
GO:1903050 26 GO:1903050 regulation of proteolysis involved in cellular protein catabolic process GOBP 251 0.3259437 1.3853373 up 0.0005764 0.0104344 1454 102800317 8078 51143 324 5071 51529 2185 84132 2272 9992
GO:1903362 26 GO:1903362 regulation of cellular protein catabolic process GOBP 258 0.3160796 1.3717395 up 0.0007141 0.0122942 1454 102800317 8078 51143 324 5071 51529 2185 84132 2272 9992
GO:0000075 27 GO:0000075 cell cycle checkpoint GOBP 232 0.4451414 1.5607109 up 0.0000054 0.0001817 9261 51143 324 51529 5884 9575 84142 8738 83695 79858 29935
GO:0051726 27 GO:0051726 regulation of cell cycle GOBP 717 0.2718467 1.3123858 up 0.0000054 0.0001817 51119 8451 5565 387 1654 5774 9903 5571 53632 22924 80139 7248 493 131870 64061 51143 324 23560 25978 51529 3727 5884 4331 26524 138151 415116 79648 51203 5608 1978 55145 8738 2081 1031 2122 5292 83695 79858 10040 3664 5314
GO:0045787 27 GO:0045787 positive regulation of cell cycle GOBP 221 0.4425823 1.5567219 up 0.0000061 0.0002011 387 1654 22924 131870 51143 51203 1978 8738 5292 83695
GO:0090068 27 GO:0090068 positive regulation of cell cycle process GOBP 177 0.4448019 1.5601811 up 0.0000424 0.0012379 387 1654 131870 51143 51203 8738 83695
GO:0010564 27 GO:0010564 regulation of cell cycle process GOBP 397 0.2952256 1.3434294 up 0.0001276 0.0029896 51119 387 1654 9903 493 131870 51143 324 25978 51529 138151 51203 8738 83695 10040 5314
GO:1901990 27 GO:1901990 regulation of mitotic cell cycle phase transition GOBP 185 0.3608653 1.4345702 up 0.0009478 0.0151915 1654 51143 324 51529 138151 8738
GO:1901987 27 GO:1901987 regulation of cell cycle phase transition GOBP 197 0.3441842 1.4108386 up 0.0011809 0.0181697 1654 493 51143 324 51529 138151 8738
GO:0007346 27 GO:0007346 regulation of mitotic cell cycle GOBP 335 0.2638461 1.3019278 up 0.0016023 0.0228979 51119 1654 5774 51143 324 25978 51529 5884 138151 415116 51203 1978 55145 8738 5292 79858 10040
GO:0006766 28 GO:0006766 vitamin metabolic process GOBP 120 -0.5489470 0.5775576 down 0.0000018 0.0000705 10135 4522 5096 6470 4337 349565 5095 25974 7421 57834
GO:0006767 28 GO:0006767 water-soluble vitamin metabolic process GOBP 91 -0.5978255 0.5500063 down 0.0000028 0.0001050 10135 4522 5096 6470 4337 349565 5095 25974
GO:0006733 28 GO:0006733 oxidoreduction coenzyme metabolic process GOBP 62 -0.7321380 0.4808798 down 0.0000034 0.0001238 23171 25824 10135 51004 51805 349565 57107 23729
GO:0019362 28 GO:0019362 pyridine nucleotide metabolic process GOBP 46 -0.5854101 0.5568774 down 0.0028520 0.0355696 23171 25824 10135 349565 23729
GO:0046496 28 GO:0046496 nicotinamide nucleotide metabolic process GOBP 46 -0.5854101 0.5568774 down 0.0028520 0.0355696 23171 25824 10135 349565 23729
GO:0019674 28 GO:0019674 NAD metabolic process GOBP 20 -0.7475618 0.4735197 down 0.0034245 0.0402228 23171 10135 349565
GO:1902600 29 GO:1902600 hydrogen ion transmembrane transport GOBP 58 -1.3752412 0.2527786 down 0.0000000 0.0000000 506 498 4697 1346 23530 7384 1327 517 1349 9377 1340 509 522 518 1329 515 10476 29796 10632 516 7388 521 514 1351 535 539 30968 1355 9551 84701
GO:0006818 29 GO:0006818 hydrogen transport GOBP 97 -1.0535783 0.3486878 down 0.0000000 0.0000000 506 498 4697 1346 23530 7384 1327 517 1349 9377 1340 509 522 518 1329 515 10476 29796 10632 516 7388 521 514 1351 535 137872 539 9114 10105 30968 1355 9551 84701
GO:0015992 29 GO:0015992 proton transport GOBP 95 -1.0552070 0.3481204 down 0.0000000 0.0000000 506 498 4697 1346 23530 7384 1327 517 1349 9377 1340 509 522 518 1329 515 10476 29796 10632 516 7388 521 514 1351 535 539 9114 10105 30968 1355 9551 84701
GO:0042776 29 GO:0042776 mitochondrial ATP synthesis coupled proton transport GOBP 30 -1.4740619 0.2289935 down 0.0000000 0.0000000 506 498 517 509 522 518 515 10476 10632 516 521 514 539 30968 9551
GO:0015985 29 GO:0015985 energy coupled proton transport, down electrochemical gradient GOBP 36 -1.3551035 0.2579206 down 0.0000000 0.0000000 506 498 517 509 522 518 515 10476 10632 516 521 514 535 539 30968 9551
GO:0015986 29 GO:0015986 ATP synthesis coupled proton transport GOBP 36 -1.3551035 0.2579206 down 0.0000000 0.0000000 506 498 517 509 522 518 515 10476 10632 516 521 514 535 539 30968 9551
GO:0006754 29 GO:0006754 ATP biosynthetic process GOBP 53 -1.1425509 0.3190042 down 0.0000000 0.0000000 506 498 2631 517 509 522 518 515 400916 10476 10632 516 521 514 535 539 30968 9551
GO:0009145 29 GO:0009145 purine nucleoside triphosphate biosynthetic process GOBP 53 -1.1425509 0.3190042 down 0.0000000 0.0000000 506 498 2631 517 509 522 518 515 400916 10476 10632 516 521 514 535 539 30968 9551
GO:0009206 29 GO:0009206 purine ribonucleoside triphosphate biosynthetic process GOBP 53 -1.1425509 0.3190042 down 0.0000000 0.0000000 506 498 2631 517 509 522 518 515 400916 10476 10632 516 521 514 535 539 30968 9551
GO:0009201 29 GO:0009201 ribonucleoside triphosphate biosynthetic process GOBP 55 -1.1147888 0.3279845 down 0.0000000 0.0000000 506 498 2631 517 509 522 518 515 400916 10476 10632 516 521 514 535 539 30968 9551
GO:1990542 29 GO:1990542 mitochondrial transmembrane transport GOBP 59 -0.9698304 0.3791473 down 0.0000000 0.0000000 506 498 517 509 522 518 515 5565 10476 10632 516 521 514 539 30968 9551 29090 51025
GO:0009127 29 GO:0009127 purine nucleoside monophosphate biosynthetic process GOBP 74 -0.9017292 0.4058672 down 0.0000000 0.0000000 506 498 122622 2631 517 509 522 518 515 400916 10476 10632 516 3615 521 514 535 539 30968 9551
GO:0009168 29 GO:0009168 purine ribonucleoside monophosphate biosynthetic process GOBP 74 -0.9017292 0.4058672 down 0.0000000 0.0000000 506 498 122622 2631 517 509 522 518 515 400916 10476 10632 516 3615 521 514 535 539 30968 9551
GO:0009156 29 GO:0009156 ribonucleoside monophosphate biosynthetic process GOBP 78 -0.8819316 0.4139825 down 0.0000000 0.0000000 506 498 122622 2631 517 509 522 518 515 400916 10476 10632 516 3615 521 514 535 539 30968 9551 132
GO:0042451 29 GO:0042451 purine nucleoside biosynthetic process GOBP 79 -0.8626288 0.4220511 down 0.0000000 0.0000000 506 498 122622 2631 517 509 522 518 515 400916 10476 10632 516 521 514 535 539 30968 9551 27430
GO:0046129 29 GO:0046129 purine ribonucleoside biosynthetic process GOBP 79 -0.8626288 0.4220511 down 0.0000000 0.0000000 506 498 122622 2631 517 509 522 518 515 400916 10476 10632 516 521 514 535 539 30968 9551 27430
GO:0009142 29 GO:0009142 nucleoside triphosphate biosynthetic process GOBP 68 -0.8873276 0.4117547 down 0.0000000 0.0000000 506 498 2631 517 509 522 518 515 400916 10476 10632 516 521 514 535 539 30968 9551 122481
GO:0009124 29 GO:0009124 nucleoside monophosphate biosynthetic process GOBP 85 -0.8127399 0.4436409 down 0.0000000 0.0000001 506 498 122622 2631 517 509 522 518 515 400916 10476 10632 516 3615 521 514 535 539 30968 9551 132
GO:0042455 29 GO:0042455 ribonucleoside biosynthetic process GOBP 86 -0.7657319 0.4649935 down 0.0000000 0.0000008 506 498 122622 2631 517 509 522 518 515 400916 10476 10632 516 521 514 535 539 30968 9551 27430
GO:0072522 29 GO:0072522 purine-containing compound biosynthetic process GOBP 193 -0.5304717 0.5883274 down 0.0000001 0.0000034 506 498 122622 2631 517 509 522 518 515 400916 10476 10632 516 358 521 514 535 539 30968 9551 27430 6470 132 117 2696
GO:0009163 29 GO:0009163 nucleoside biosynthetic process GOBP 101 -0.6739901 0.5096709 down 0.0000002 0.0000068 506 498 122622 2631 517 509 522 518 515 400916 10476 10632 516 521 514 535 539 30968 9551 27430 1723
GO:1901659 29 GO:1901659 glycosyl compound biosynthetic process GOBP 102 -0.6632199 0.5151898 down 0.0000002 0.0000100 506 498 122622 2631 517 509 522 518 515 400916 10476 10632 516 521 514 535 539 30968 9551 27430 1723
GO:0009152 29 GO:0009152 purine ribonucleotide biosynthetic process GOBP 159 -0.5378888 0.5839799 down 0.0000004 0.0000156 506 498 122622 2631 517 509 522 518 515 400916 10476 10632 516 358 521 514 535 539 30968 9551 117 2696
GO:0006164 29 GO:0006164 purine nucleotide biosynthetic process GOBP 168 -0.5142648 0.5979401 down 0.0000010 0.0000389 506 498 122622 2631 517 509 522 518 515 400916 10476 10632 516 358 521 514 535 539 30968 9551 117 2696
GO:0009260 29 GO:0009260 ribonucleotide biosynthetic process GOBP 163 -0.5129149 0.5987477 down 0.0000012 0.0000501 506 498 122622 2631 517 509 522 518 515 400916 10476 10632 516 358 521 514 535 539 30968 9551 117 2696
GO:0046390 29 GO:0046390 ribose phosphate biosynthetic process GOBP 165 -0.4889704 0.6132575 down 0.0000041 0.0001472 506 498 122622 2631 517 509 522 518 515 400916 10476 10632 516 358 521 514 535 539 30968 9551 117 2696
GO:0009165 29 GO:0009165 nucleotide biosynthetic process GOBP 214 -0.4394563 0.6443867 down 0.0000048 0.0001655 506 498 122622 2631 517 509 522 518 515 400916 10476 10632 516 358 521 514 535 539 30968 9551 349565 2762 117 2696 122481
GO:1901293 29 GO:1901293 nucleoside phosphate biosynthetic process GOBP 235 -0.4264480 0.6528238 down 0.0000050 0.0001718 506 498 122622 2631 517 509 522 518 515 400916 10476 10632 516 358 3615 521 514 535 539 30968 9551 132 349565 2762 117 2696 122481
GO:0090407 29 GO:0090407 organophosphate biosynthetic process GOBP 483 -0.3096157 0.7337289 down 0.0000058 0.0001914 506 498 122622 2631 517 23171 509 522 518 515 400916 10476 10632 516 358 3615 521 514 6342 117283 535 161247 539 30968 2181 376497 9551 81579 54675 6901 4337 56261 5833 55326 132 349565 255189 5154 2185 2762 117 2696 122481
GO:0006839 29 GO:0006839 mitochondrial transport GOBP 248 -0.3552633 0.7009888 down 0.0000788 0.0019974 506 498 9927 3313 517 509 8604 522 518 515 5565 140735 10476 10632 516 521 514 539 10105 30968 23203 9551 29090 10651 5071 92609 10018 7263 4285 578 79753 51025 90506
GO:0045333 30 GO:0045333 cellular respiration GOBP 182 -1.5562018 0.2109357 down 0.0000000 0.0000000 506 498 3418 50 1431 4191 4967 7385 7381 4697 23530 4719 6389 7384 1327 517 4720 1349 1350 4715 54205 7386 9377 4716 1340 1537 509 8604 4723 522 518 1738 1329 515 5160 4698 6390 10476 4710 8803 4705 29796 1345 10632 8801 1743 27089 5162 4694 516 8802 4725 2271 7388 521 4711 514 54539 4722 4717 55967 1351 4709 4708 4728 4706 4731 4724 4702 6391 539 4707 4726 55526 1355 9551 4695 4712 6901 23410 4704 2109 10873 79675 90639 4714 9016 84701 55753
GO:0006091 30 GO:0006091 generation of precursor metabolites and energy GOBP 407 -0.9780516 0.3760431 down 0.0000000 0.0000000 506 291 498 7167 3418 50 1431 4191 5250 2631 4967 7385 7381 4697 1346 23530 4719 6389 7384 2821 1327 517 4720 1349 1350 4715 54205 7386 9377 4716 1340 1537 509 8604 4723 522 518 1738 1329 515 5565 5160 4698 6390 400916 10476 4710 8803 4705 29796 1345 10632 8801 1743 27089 5162 4694 516 8802 4725 2271 7388 521 4711 514 54539 4722 4717 55967 1351 5571 4709 4708 4728 4706 4731 4724 4702 6391 6844 539 4707 4726 10105 55526 1355 9551 4695 4712 6901 23410 957 4704 2109 4899 10873 79675 109 90639 4714 2788 9016 84701 9942 55753 777 116285 2696 2785
GO:0015980 30 GO:0015980 energy derivation by oxidation of organic compounds GOBP 324 -1.0399016 0.3534895 down 0.0000000 0.0000000 506 291 498 3418 50 1431 4191 4967 7385 7381 4697 23530 4719 6389 7384 1327 517 4720 1349 1350 4715 54205 7386 9377 4716 1340 1537 509 8604 4723 522 518 1738 1329 515 5565 5160 4698 6390 10476 4710 8803 4705 29796 1345 10632 8801 1743 27089 5162 4694 516 8802 4725 2271 7388 521 4711 514 54539 4722 4717 55967 1351 4709 4708 4728 4706 4731 4724 4702 6391 6844 539 4707 4726 55526 1355 9551 4695 4712 6901 23410 4704 2109 10873 79675 109 90639 4714 2788 9016 84701 55753 777 116285 2785
GO:0055114 30 GO:0055114 oxidation-reduction process GOBP 549 -0.8524048 0.4263883 down 0.0000000 0.0000000 506 291 498 3418 50 1431 5166 4191 4967 7385 7381 4697 23530 4719 6389 7384 1327 34 517 4720 1349 1350 4715 54205 7386 9377 4716 1340 1537 509 8604 4723 522 518 1738 10935 1329 515 5565 5160 4698 6390 10476 4710 8803 4705 29796 1345 10632 8801 1743 27089 5162 4694 516 1892 8802 4725 2271 7388 373156 521 4711 514 25824 54539 4722 4717 55967 6342 1351 25828 4709 4708 4728 4706 4731 4724 1666 79602 9380 4702 6391 6844 539 4707 4726 5096 51295 55526 1632 1355 9551 3052 4695 4712 30 6901 23410 4704 54996 2109 10873 79675 9645 55217 84693 5095 109 90639 7263 4714 2788 137902 1571 441282 1962 9016 84701 51268 55753 777 116285 57834 2785
GO:0015672 31 GO:0015672 monovalent inorganic cation transport GOBP 385 -0.4381699 0.6452161 down 0.0000000 0.0000004 506 498 4697 1346 23530 7384 1327 517 1349 23171 9377 1340 509 522 518 1329 515 5565 10476 29796 10632 516 5774 7388 358 521 514 1351 535 539 9114 493 10105 30968 1355 9551 6558 6330 5071 2745 4704 6327 2185 3764 1259 3760 84701 53828 6323 9992
GO:0098662 31 GO:0098662 inorganic cation transmembrane transport GOBP 392 -0.4101158 0.6635734 down 0.0000000 0.0000010 488 10345 506 498 4697 1346 23530 7384 782 1327 517 1349 23171 9377 1340 509 522 518 1329 515 5565 10476 29796 10632 6786 516 5774 7388 358 521 514 1351 535 539 493 30968 1355 9551 6558 6330 2745 6327 23516 3764 1259 3760 84701 125336 53828 6323 9992 7442
GO:0098655 31 GO:0098655 cation transmembrane transport GOBP 424 -0.3725871 0.6889497 down 0.0000002 0.0000080 488 10345 506 498 4697 1346 23530 7384 782 1327 517 1349 23171 9377 1340 509 522 518 1329 515 5565 10476 29796 10632 6786 516 5774 7388 358 521 514 1351 535 539 493 30968 1355 9551 6558 6330 2745 6327 23516 3764 1259 3760 84701 125336 53828 6323 9992 7442
GO:0098660 31 GO:0098660 inorganic ion transmembrane transport GOBP 434 -0.3677814 0.6922685 down 0.0000002 0.0000087 488 10345 506 498 5250 4697 1346 23530 7384 782 1327 517 1349 23171 9377 1340 509 522 518 1329 515 5565 10476 29796 10632 6786 516 5774 7388 358 521 514 1351 535 539 493 30968 1355 9551 6558 6330 2745 6327 1184 23516 3764 2743 1259 3760 84701 115111 125336 338440 53828 6323 9992 7442
GO:0034220 31 GO:0034220 ion transmembrane transport GOBP 685 -0.2451825 0.7825617 down 0.0000491 0.0013918 488 10345 506 498 7416 5250 4697 1346 23530 7419 7384 782 1327 517 1349 23171 9377 1340 509 8604 522 518 1329 515 5565 10476 29796 7417 10632 6786 516 5774 7388 358 521 514 1351 535 539 493 10105 30968 1355 9551 6558 6330 5355 2745 6507 6327 2697 1184 578 2185 23516 3764 2743 1259 3760 84701 220963 6781 2570 115111 2892 125336 338440 53828 6323 9992 7442 2557
GO:0006812 31 GO:0006812 cation transport GOBP 778 -0.1906948 0.8263848 down 0.0014770 0.0213728 488 10345 506 498 4697 1346 23530 7384 782 1327 517 1349 23171 9377 1340 509 522 518 1329 515 5565 10476 29796 10632 6786 516 5774 7388 358 521 514 1351 535 539 9114 493 10105 59285 30968 1355 9551 6558 6330 5071 2745 4704 6327 2185 23516 3764 4283 1259 3760 84701 6781 125336 1234 53828 6323 9992 777 7442 6355
GO:0006396 32 GO:0006396 RNA processing GOBP 653 0.4273851 1.5332430 up 0.0000000 0.0000000 1655 6427 4670 10922 10291 708 23405 3188 54623 79622 6832 1196 4331 6732 10283 57703 1479 83640 79753 2081 22944 25888 5936 1973
GO:0006397 32 GO:0006397 mRNA processing GOBP 486 0.4601659 1.5843367 up 0.0000000 0.0000007 1655 6427 4670 10291 708 3188 54623 4331 6732 10283 57703 1479 83640 2081 22944 25888 5936 1973
GO:0016071 32 GO:0016071 mRNA metabolic process GOBP 684 0.3794470 1.4614762 up 0.0000000 0.0000011 7812 6175 1655 6427 4670 10291 708 3188 115752 54623 131870 6832 4331 6732 10283 57703 1479 83640 2081 22944 25888 5936 1973
GO:0008380 32 GO:0008380 RNA splicing GOBP 442 0.4111173 1.5085022 up 0.0000013 0.0000526 1655 6427 4670 10922 10291 708 3188 79622 1196 6732 10283 57703 1479 2081 5936
GO:0000375 32 GO:0000375 RNA splicing, via transesterification reactions GOBP 361 0.4372052 1.5483738 up 0.0000035 0.0001266 1655 6427 4670 10291 708 3188 6732 10283 57703 1479 5936
GO:0000377 32 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile GOBP 353 0.4341870 1.5437075 up 0.0000047 0.0001625 1655 6427 4670 10291 708 3188 6732 10283 57703 1479 5936
GO:0000398 32 GO:0000398 mRNA splicing, via spliceosome GOBP 353 0.4341870 1.5437075 up 0.0000047 0.0001625 1655 6427 4670 10291 708 3188 6732 10283 57703 1479 5936
GO:0043484 32 GO:0043484 regulation of RNA splicing GOBP 72 0.5986636 1.8196854 up 0.0002544 0.0052523 1655 10922 10291 708 1196 6732 57703 2081 5936
GO:1903311 32 GO:1903311 regulation of mRNA metabolic process GOBP 85 0.5370140 1.7108905 up 0.0005794 0.0104468 1655 10291 708 54623 6732 57703 5936
GO:0050684 32 GO:0050684 regulation of mRNA processing GOBP 75 0.5412791 1.7182032 up 0.0010068 0.0160257 1655 10291 708 54623 6732 57703 5936
GO:0006090 33 GO:0006090 pyruvate metabolic process GOBP 77 -0.6807958 0.5062140 down 0.0000005 0.0000200 7167 5166 2821 5164 1738 5160 5162 1737 51660 3945 5571 54704 957 10873
GO:0006086 33 GO:0006086 acetyl-CoA biosynthetic process from pyruvate GOBP 17 -1.0990739 0.3331795 down 0.0000046 0.0001625 5166 5164 1738 5160 5162 1737 54704
GO:0010510 33 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate GOBP 15 -1.0990739 0.3331795 down 0.0000046 0.0001625 5166 5164 1738 5160 5162 1737 54704
GO:0050812 33 GO:0050812 regulation of acyl-CoA biosynthetic process GOBP 15 -1.0990739 0.3331795 down 0.0000046 0.0001625 5166 5164 1738 5160 5162 1737 54704
GO:0006085 33 GO:0006085 acetyl-CoA biosynthetic process GOBP 19 -1.0211398 0.3601842 down 0.0000110 0.0003506 5166 5164 1738 5160 5162 1737 54704
GO:0051193 33 GO:0051193 regulation of cofactor metabolic process GOBP 18 -0.9505712 0.3865202 down 0.0000478 0.0013608 5166 5164 1738 5160 5162 1737 54704
GO:0051196 33 GO:0051196 regulation of coenzyme metabolic process GOBP 18 -0.9505712 0.3865202 down 0.0000478 0.0013608 5166 5164 1738 5160 5162 1737 54704
GO:0042762 33 GO:0042762 regulation of sulfur metabolic process GOBP 19 -0.9223031 0.3976023 down 0.0000621 0.0016670 5166 5164 1738 5160 5162 1737 54704
GO:0019217 33 GO:0019217 regulation of fatty acid metabolic process GOBP 50 -0.6593610 0.5171817 down 0.0000690 0.0018091 5166 5164 1738 5565 5160 5162 1737 54704 7376
GO:0006637 33 GO:0006637 acyl-CoA metabolic process GOBP 60 -0.6087385 0.5440367 down 0.0000754 0.0019445 5166 5164 1738 5160 8803 8801 5162 1737 54704 84693 641371 283927 51268
GO:0035383 33 GO:0035383 thioester metabolic process GOBP 60 -0.6087385 0.5440367 down 0.0000754 0.0019445 5166 5164 1738 5160 8803 8801 5162 1737 54704 84693 641371 283927 51268
GO:0035384 33 GO:0035384 thioester biosynthetic process GOBP 35 -0.7090338 0.4921194 down 0.0002219 0.0046558 5166 5164 1738 5160 5162 1737 54704
GO:0071616 33 GO:0071616 acyl-CoA biosynthetic process GOBP 35 -0.7090338 0.4921194 down 0.0002219 0.0046558 5166 5164 1738 5160 5162 1737 54704
GO:0006084 33 GO:0006084 acetyl-CoA metabolic process GOBP 23 -0.7729671 0.4616413 down 0.0011337 0.0176196 5166 5164 1738 5160 5162 1737 54704 283927 51268
GO:0042180 33 GO:0042180 cellular ketone metabolic process GOBP 173 -0.3173315 0.7280894 down 0.0025479 0.0330364 5166 5164 1738 5565 5160 231 4947 5162 1737 6342 54704 493 51582 7376 51004 8574 1196 51805 57107 57834
GO:0043648 34 GO:0043648 dicarboxylic acid metabolic process GOBP 53 -0.8847834 0.4128036 down 0.0000000 0.0000000 3418 4191 2806 6389 2805 4522 137872 2746 2730 6470 10873
GO:0009068 34 GO:0009068 aspartate family amino acid catabolic process GOBP 17 -1.1789183 0.3076113 down 0.0000000 0.0000007 2806 4967 2805 1738 1743 2639 501 89874 51268
GO:0009066 34 GO:0009066 aspartate family amino acid metabolic process GOBP 43 -0.9301830 0.3944815 down 0.0000000 0.0000008 2806 4967 2805 1738 1743 6611 2639 501 79896 89874 51268
GO:0009064 34 GO:0009064 glutamine family amino acid metabolic process GOBP 36 -0.8446282 0.4297171 down 0.0000014 0.0000559 2806 2805 493 2746 8659 2730
GO:0006553 34 GO:0006553 lysine metabolic process GOBP 10 -1.2169403 0.2961349 down 0.0000028 0.0001050 4967 1738 1743 2639 501 89874 51268
GO:0006554 34 GO:0006554 lysine catabolic process GOBP 10 -1.2169403 0.2961349 down 0.0000028 0.0001050 4967 1738 1743 2639 501 89874 51268
GO:0008652 34 GO:0008652 cellular amino acid biosynthetic process GOBP 61 -0.6499575 0.5220680 down 0.0000384 0.0011358 2806 2805 493 2746 376497 2875 79896
GO:0006536 34 GO:0006536 glutamate metabolic process GOBP 14 -0.9866666 0.3728174 down 0.0000579 0.0015635 2806 2805 2746 2730
GO:0006103 34 GO:0006103 2-oxoglutarate metabolic process GOBP 13 -1.0046692 0.3661658 down 0.0000690 0.0018091 3418 2806 2805 137872
GO:0043649 34 GO:0043649 dicarboxylic acid catabolic process GOBP 11 -1.0077661 0.3650335 down 0.0001259 0.0029640 2806 2805 2746
GO:1901607 34 GO:1901607 alpha-amino acid biosynthetic process GOBP 50 -0.5554397 0.5738199 down 0.0019398 0.0267293 2805 493 2746 376497 79896
GO:0005996 34 GO:0005996 monosaccharide metabolic process GOBP 189 -0.2975676 0.7426224 down 0.0035566 0.0412489 7167 5166 4191 2806 4190 2805 2821 8604 5164 8402 6097 5071 1196 92579 51363 130589 6652 8534 9942 89792
GO:0007017 35 GO:0007017 microtubule-based process GOBP 457 0.3567338 1.4286555 up 0.0000022 0.0000855 10345 23095 51119 10128 55700 387 324 25978 1874 6993 6904 51673 28989 26146 8546 51203 10636 92104 3797 345895 4744 81930 221458 221150 5314
GO:0000226 35 GO:0000226 microtubule cytoskeleton organization GOBP 302 0.3567945 1.4287422 up 0.0000785 0.0019974 10345 51119 55700 387 324 25978 6993 6904 51673 28989 51203 10636 345895 81930 221150 5314
GO:0070925 35 GO:0070925 organelle assembly GOBP 362 0.2742878 1.3155934 up 0.0005927 0.0106453 51119 387 1654 9114 708 25978 1874 80152 28988 26146 92104 57216 345895 51364 5314
GO:1901566 36 GO:1901566 organonitrogen compound biosynthetic process GOBP 600 -0.3326008 0.7170564 down 0.0000001 0.0000039 506 498 122622 2631 2806 2805 517 509 522 518 515 400916 10476 8803 10632 516 9218 358 521 514 535 9334 539 493 2948 30968 2181 2746 376497 1355 9551 27430 4258 2875 2730 26873 151742 6470 4337 8879 132 349565 79017 3145 51363 9469 64949 1723 79896 222537 117 8534 10675 11081 2696
GO:0045087 37 GO:0045087 innate immune response GOBP 773 0.2444222 1.2768833 up 0.0000248 0.0007574 5588 1654 9261 1508 9093 10383 7376 2308 84265 51447 7706 79671 466 6732 109 5608 4773 5154 10621 2185 2066 51728 11277 3929 6288 5137 5971 8347 9542 57823 3664
GO:0001817 37 GO:0001817 regulation of cytokine production GOBP 412 0.3082550 1.3610480 up 0.0001082 0.0026286 23139 5588 1654 9261 708 51665 84265 10524 7706 79671 26146 66005 10621 2324 51728 3606 11277 3929 6288 5971
GO:0001819 37 GO:0001819 positive regulation of cytokine production GOBP 286 0.3583427 1.4309559 up 0.0001563 0.0034987 5588 1654 708 84265 10621 2324 51728 3606 11277 3929 6288
GO:0001816 37 GO:0001816 cytokine production GOBP 448 0.2868972 1.3322873 up 0.0001978 0.0042463 23139 5588 1654 9261 708 30968 51665 84265 10524 7706 79671 26146 66005 10621 2324 51728 3606 11277 3929 6288 5971
GO:0032479 37 GO:0032479 regulation of type I interferon production GOBP 123 0.4926261 1.6366085 up 0.0003201 0.0063965 1654 84265 7706 79671 26146 10621 51728 11277 5971
GO:0032606 37 GO:0032606 type I interferon production GOBP 127 0.4926261 1.6366085 up 0.0003201 0.0063965 1654 84265 7706 79671 26146 10621 51728 11277 5971
GO:0016568 38 GO:0016568 chromatin modification GOBP 478 0.3774098 1.4585018 up 0.0000003 0.0000121 80218 9878 5245 8242 5585 23028 54623 64324 10524 6599 80152 54108 3148 9575 138151 56970 9682 22823 7862 2099 54556 3622 25855 6839 11339 79858 90665
GO:0006325 38 GO:0006325 chromatin organization GOBP 696 0.3419997 1.4077599 up 0.0000004 0.0000172 80218 9878 5245 8242 6944 5585 23028 54623 64324 6832 10524 6599 80152 54108 3148 9575 6732 138151 56970 9682 22823 7862 2099 54556 3622 25855 6839 11339 79858 8347 90665
GO:0016570 38 GO:0016570 histone modification GOBP 342 0.3402697 1.4053265 up 0.0000648 0.0017294 80218 5245 8242 5585 23028 54623 64324 10524 9575 138151 56970 9682 22823 7862 54556 25855 6839 79858 90665
GO:0016569 38 GO:0016569 covalent chromatin modification GOBP 346 0.3375846 1.4015582 up 0.0000683 0.0018091 80218 5245 8242 5585 23028 54623 64324 10524 9575 138151 56970 9682 22823 7862 54556 25855 6839 79858 90665
GO:0018205 38 GO:0018205 peptidyl-lysine modification GOBP 237 0.3780026 1.4593667 up 0.0001456 0.0033427 80218 23408 64324 10524 23410 9575 22823 79918 7862 54556 6839 196541
GO:0016573 38 GO:0016573 histone acetylation GOBP 114 0.4439782 1.5588965 up 0.0009297 0.0149533 80218 10524 9575 7862 54556
GO:0018393 38 GO:0018393 internal peptidyl-lysine acetylation GOBP 116 0.4369145 1.5479237 up 0.0010292 0.0162699 80218 10524 9575 7862 54556
GO:0018394 38 GO:0018394 peptidyl-lysine acetylation GOBP 120 0.4154298 1.5150217 up 0.0016427 0.0233308 80218 10524 9575 7862 54556
GO:0043543 38 GO:0043543 protein acylation GOBP 173 0.3374970 1.4014354 up 0.0031115 0.0374029 4191 80218 2308 10524 51201 9575 340481 7862 54556 1962
GO:0022900 39 GO:0022900 electron transport chain GOBP 134 -1.5954625 0.2028147 down 0.0000000 0.0000000 506 498 7385 7381 4697 4719 6389 7384 1327 517 4720 1349 1350 4715 54205 7386 9377 4716 1340 1537 509 8604 4723 522 518 1329 515 4698 6390 10476 4710 4705 29796 1345 10632 27089 4694 516 4725 7388 521 4711 514 54539 4722 4717 55967 1351 4709 4708 4728 4706 4731 4724 4702 6391 539 4707 4726 1355 9551 4695 4712 6901 4704 2109 4714
GO:0022904 39 GO:0022904 respiratory electron transport chain GOBP 132 -1.5978869 0.2023236 down 0.0000000 0.0000000 506 498 7385 7381 4697 4719 6389 7384 1327 517 4720 1349 1350 4715 54205 7386 9377 4716 1340 1537 509 8604 4723 522 518 1329 515 4698 6390 10476 4710 4705 29796 1345 10632 27089 4694 516 4725 7388 521 4711 514 54539 4722 4717 55967 1351 4709 4708 4728 4706 4731 4724 4702 6391 539 4707 4726 1355 9551 4695 4712 6901 4704 2109 4714
GO:0009144 39 GO:0009144 purine nucleoside triphosphate metabolic process GOBP 122 -1.3428971 0.2610882 down 0.0000000 0.0000000 506 498 2631 7385 7381 4697 4719 7384 517 4720 4715 54205 4716 509 4723 522 518 515 4698 400916 10476 4710 4705 29796 10632 4694 516 4725 7388 521 4711 514 4722 4717 4709 4708 4728 4706 4731 535 4724 4702 539 4707 4726 10105 30968 131870 1355 9551 4695 4712 6901 957 4704 4714
GO:0046034 39 GO:0046034 ATP metabolic process GOBP 117 -1.3664512 0.2550103 down 0.0000000 0.0000000 506 498 2631 7385 7381 4697 4719 7384 517 4720 4715 54205 4716 509 4723 522 518 515 4698 400916 10476 4710 4705 29796 10632 4694 516 4725 7388 521 4711 514 4722 4717 4709 4708 4728 4706 4731 535 4724 4702 539 4707 4726 10105 30968 1355 9551 4695 4712 6901 957 4704 4714
GO:0009205 39 GO:0009205 purine ribonucleoside triphosphate metabolic process GOBP 118 -1.3596208 0.2567581 down 0.0000000 0.0000000 506 498 2631 7385 7381 4697 4719 7384 517 4720 4715 54205 4716 509 4723 522 518 515 4698 400916 10476 4710 4705 29796 10632 4694 516 4725 7388 521 4711 514 4722 4717 4709 4708 4728 4706 4731 535 4724 4702 539 4707 4726 10105 30968 1355 9551 4695 4712 6901 957 4704 4714
GO:0009199 39 GO:0009199 ribonucleoside triphosphate metabolic process GOBP 120 -1.3472366 0.2599576 down 0.0000000 0.0000000 506 498 2631 7385 7381 4697 4719 7384 517 4720 4715 54205 4716 509 4723 522 518 515 4698 400916 10476 4710 4705 29796 10632 4694 516 4725 7388 521 4711 514 4722 4717 4709 4708 4728 4706 4731 535 4724 4702 539 4707 4726 10105 30968 1355 9551 4695 4712 6901 957 4704 4714
GO:0009141 39 GO:0009141 nucleoside triphosphate metabolic process GOBP 140 -1.2248872 0.2937908 down 0.0000000 0.0000000 506 498 2631 7385 7381 4697 4719 7384 517 4720 4715 54205 4716 509 4723 522 518 515 4698 400916 10476 4710 4705 29796 10632 4694 516 4725 7388 521 4711 514 4722 4717 4709 4708 4728 4706 4731 535 4724 4702 539 4707 4726 10105 30968 131870 1355 9551 4695 4712 6901 957 4704 79077 4714 122481
GO:0009126 39 GO:0009126 purine nucleoside monophosphate metabolic process GOBP 145 -1.2007647 0.3009640 down 0.0000000 0.0000000 506 498 122622 2631 7385 7381 4697 4719 7384 517 4720 4715 54205 4716 509 4723 522 518 515 4698 400916 10476 4710 4705 29796 10632 4694 516 4725 7388 3615 521 4711 514 4722 4717 4709 4708 4728 4706 4731 535 4724 4702 539 4707 4726 10105 30968 1355 9551 4695 4712 6901 957 4704 4714
GO:0009167 39 GO:0009167 purine ribonucleoside monophosphate metabolic process GOBP 145 -1.2007647 0.3009640 down 0.0000000 0.0000000 506 498 122622 2631 7385 7381 4697 4719 7384 517 4720 4715 54205 4716 509 4723 522 518 515 4698 400916 10476 4710 4705 29796 10632 4694 516 4725 7388 3615 521 4711 514 4722 4717 4709 4708 4728 4706 4731 535 4724 4702 539 4707 4726 10105 30968 1355 9551 4695 4712 6901 957 4704 4714
GO:0009161 39 GO:0009161 ribonucleoside monophosphate metabolic process GOBP 149 -1.1876029 0.3049514 down 0.0000000 0.0000000 506 498 122622 2631 7385 7381 4697 4719 7384 517 4720 4715 54205 4716 509 4723 522 518 515 4698 400916 10476 4710 4705 29796 10632 4694 516 4725 7388 3615 521 4711 514 4722 4717 4709 4708 4728 4706 4731 535 4724 4702 539 4707 4726 10105 30968 1355 9551 4695 4712 6901 957 4704 132 4714
GO:0009123 39 GO:0009123 nucleoside monophosphate metabolic process GOBP 159 -1.1456957 0.3180026 down 0.0000000 0.0000000 506 498 122622 2631 7385 7381 4697 4719 7384 517 4720 4715 54205 4716 509 4723 522 518 515 4698 400916 10476 4710 4705 29796 10632 4694 516 4725 7388 3615 521 4711 514 4722 4717 4709 4708 4728 4706 4731 535 4724 4702 539 4707 4726 10105 30968 1355 9551 4695 4712 6901 957 4704 132 4714
GO:0046128 39 GO:0046128 purine ribonucleoside metabolic process GOBP 176 -1.0615222 0.3459288 down 0.0000000 0.0000000 506 498 122622 2631 7385 7381 4697 4719 7384 517 4720 4715 54205 4716 509 4723 522 518 515 4698 400916 10476 4710 4705 29796 10632 4694 516 4725 7388 521 4711 514 4722 4717 4709 4708 4728 4706 4731 535 4724 4702 539 4707 4726 10105 30968 1355 9551 27430 4695 4712 6901 957 4704 84693 4714 64172 112858 283927
GO:0042278 39 GO:0042278 purine nucleoside metabolic process GOBP 180 -1.0521818 0.3491751 down 0.0000000 0.0000000 506 498 122622 2631 7385 7381 4697 4719 7384 517 4720 4715 54205 4716 509 4723 522 518 515 4698 400916 10476 4710 4705 29796 10632 4694 516 4725 7388 521 4711 514 4722 4717 4709 4708 4728 4706 4731 535 4724 4702 539 4707 4726 10105 30968 1355 9551 27430 4695 4712 6901 957 4704 84693 4714 64172 112858 283927
GO:1901657 39 GO:1901657 glycosyl compound metabolic process GOBP 240 -0.9237654 0.3970213 down 0.0000000 0.0000000 506 498 122622 2631 7385 7381 4697 4719 7384 517 4720 4715 54205 4716 509 4723 522 518 515 4698 400916 10476 4710 4705 29796 231 10632 4694 516 4725 7388 521 4711 514 4722 4717 4709 4708 4728 4706 4731 535 4724 4702 539 4707 4726 10105 30968 1355 9551 27430 4695 4712 6901 957 8574 4704 84693 51071 4714 64172 1723 56953 112858 283927 8382
GO:0009119 39 GO:0009119 ribonucleoside metabolic process GOBP 192 -0.9810987 0.3748990 down 0.0000000 0.0000000 506 498 122622 2631 7385 7381 4697 4719 7384 517 4720 4715 54205 4716 509 4723 522 518 515 4698 400916 10476 4710 4705 29796 10632 4694 516 4725 7388 521 4711 514 4722 4717 4709 4708 4728 4706 4731 535 4724 4702 539 4707 4726 10105 30968 1355 9551 27430 4695 4712 6901 957 4704 84693 4714 64172 112858 283927
GO:0009116 39 GO:0009116 nucleoside metabolic process GOBP 225 -0.9264270 0.3959660 down 0.0000000 0.0000000 506 498 122622 2631 7385 7381 4697 4719 7384 517 4720 4715 54205 4716 509 4723 522 518 515 4698 400916 10476 4710 4705 29796 10632 4694 516 4725 7388 521 4711 514 4722 4717 4709 4708 4728 4706 4731 535 4724 4702 539 4707 4726 10105 30968 1355 9551 27430 4695 4712 6901 957 4704 84693 51071 4714 64172 1723 56953 112858 283927 8382
GO:0016482 40 GO:0016482 cytoplasmic transport GOBP 913 0.2027596 1.2247780 up 0.0001393 0.0032152 488 10345 6175 9927 8615 3313 387 950 10972 3836 9218 6427 29959 11124 6844 7248 493 2181 23203 29090 10651 5071 92609 83547 25937 84079 130617 7263 4285 2185 5193 79753 2066 10636 4283 5936 51025 1234 51361 90506
GO:0070647 41 GO:0070647 protein modification by small protein conjugation or removal GOBP 718 0.2820515 1.3258470 up 0.0000056 0.0001878 5588 9903 267 9093 80344 10477 8078 54623 84937 79872 55832 5071 23560 51529 10193 92912 6049 9666 56970 84231 6477 64320 143684 2185 84132 57531 83932
GO:0032446 41 GO:0032446 protein modification by small protein conjugation GOBP 604 0.2584542 1.2949268 up 0.0001162 0.0027787 5588 9903 267 9093 80344 10477 54623 84937 79872 55832 5071 23560 51529 10193 92912 6049 9666 84231 6477 64320 2185 57531 83932
GO:0016567 41 GO:0016567 protein ubiquitination GOBP 554 0.2361919 1.2664173 up 0.0006611 0.0116039 5588 9903 267 9093 80344 10477 54623 84937 79872 55832 5071 23560 51529 10193 92912 6049 9666 84231 6477 64320 2185 57531 83932
GO:0006974 42 GO:0006974 cellular response to DNA damage stimulus GOBP 778 0.2519248 1.2864993 up 0.0000528 0.0014656 1655 9261 142 1454 102800317 64965 23028 131870 2308 324 10524 56897 5884 4331 3148 64963 9575 138151 92667 84142 254225 10018 5608 4773 84515 64949 578 8738 3622 4595 4437 22944 83932 6839 83695 11277 79858 29935
GO:0007059 43 GO:0007059 chromosome segregation GOBP 199 0.3863437 1.4715904 up 0.0003547 0.0069676 80218 1654 51647 324 25978 51529 80152 84191 28989 6732 51203 10636 81930 221150 256126
GO:0000280 43 GO:0000280 nuclear division GOBP 282 0.3227180 1.3808759 up 0.0004103 0.0078255 80218 3306 387 2029 324 25978 51529 51203 3622 4437 10040 81930 221150 256126
GO:0000819 43 GO:0000819 sister chromatid segregation GOBP 111 0.4676803 1.5962870 up 0.0008721 0.0141243 80218 324 25978 51529 51203 81930
GO:0048285 43 GO:0048285 organelle fission GOBP 322 0.2810757 1.3245539 up 0.0012314 0.0186336 80218 3306 387 2029 10059 324 5071 25978 51529 51203 3622 4437 2066 10040 81930 221150 256126
GO:0000070 43 GO:0000070 mitotic sister chromatid segregation GOBP 108 0.4555507 1.5770417 up 0.0014527 0.0211535 80218 324 25978 51529 51203 81930
GO:0051640 43 GO:0051640 organelle localization GOBP 292 0.2841893 1.3286844 up 0.0018740 0.0259768 9927 10128 10497 10972 6844 5071 25978 6993 6810 51199 8546 51203 9066 26276 5864 57586 81930
GO:0007067 43 GO:0007067 mitotic nuclear division GOBP 221 0.3070550 1.3594157 up 0.0028665 0.0355696 80218 387 2029 324 25978 51529 51203 10040 81930 221150
GO:0006575 44 GO:0006575 cellular modified amino acid metabolic process GOBP 151 -0.4605938 0.6309089 down 0.0000182 0.0005700 1158 1160 2806 4522 2686 493 2948 376497 27430 81579 8659 1152 4258 2730 26873 6470 10797 79017 255189 87769
GO:0042398 44 GO:0042398 cellular modified amino acid biosynthetic process GOBP 31 -0.6740452 0.5096428 down 0.0013313 0.0197598 493 376497 27430 4258 2730 26873 79017
GO:0043043 44 GO:0043043 peptide biosynthetic process GOBP 21 -0.7582422 0.4684892 down 0.0028121 0.0354665 4258 2730 26873 79017 64949
GO:0032543 45 GO:0032543 mitochondrial translation GOBP 119 -1.0551949 0.3481246 down 0.0000000 0.0000000 7284 28973 64960 55245 64432 51253 51081 29088 23107 55173 51021 708 7818 64965 51318 64969 80222 84340 51650 54948 64975 5188 219927 64968 64963 10102 64979 54516 64949
GO:0070126 45 GO:0070126 mitochondrial translational termination GOBP 82 -1.0715553 0.3424754 down 0.0000000 0.0000000 28973 64960 64432 51253 51081 29088 23107 55173 51021 7818 64965 51318 64969 84340 51650 54948 64975 219927 64968 64963 64979 54516 64949
GO:0070125 45 GO:0070125 mitochondrial translational elongation GOBP 83 -1.0404622 0.3532914 down 0.0000000 0.0000000 7284 28973 64960 64432 51253 51081 29088 23107 55173 51021 7818 64965 51318 64969 51650 54948 64975 219927 64968 64963 10102 64979 64949
GO:0070124 45 GO:0070124 mitochondrial translational initiation GOBP 83 -1.0074565 0.3651466 down 0.0000000 0.0000000 28973 64960 64432 51253 51081 29088 23107 55173 51021 7818 64965 51318 64969 51650 54948 64975 219927 64968 64963 64979 64949
GO:0006415 45 GO:0006415 translational termination GOBP 171 -0.5869831 0.5560022 down 0.0000000 0.0000000 6175 28973 64960 64432 51253 51081 29088 23107 55173 51021 7818 64965 51318 64969 84340 51650 54948 64975 219927 64968 64963 64979 54516 64949
GO:0006414 45 GO:0006414 translational elongation GOBP 183 -0.5540532 0.5746161 down 0.0000000 0.0000000 6175 7284 28973 64960 64432 51253 51081 29088 23107 55173 51021 7818 64965 51318 64969 51650 54948 64975 219927 64968 64963 10102 64979 64949
GO:0043624 45 GO:0043624 cellular protein complex disassembly GOBP 227 -0.4332013 0.6484299 down 0.0000003 0.0000133 6175 51119 28973 64960 64432 51253 51081 29088 23107 55173 51021 7818 64965 51318 64969 84340 51650 54948 64975 324 219927 64968 64963 64979 9645 54516 64949 81930
GO:0006412 45 GO:0006412 translation GOBP 691 -0.2880290 0.7497399 down 0.0000088 0.0002806 6175 27335 1654 5859 7284 4677 28973 64960 51520 55245 64432 51253 51081 29088 8664 23107 55173 51021 7248 708 7818 64965 51318 64969 8891 80222 84340 51650 54948 64975 51116 5188 8890 219927 64968 64963 10102 64979 79731 54516 1978 64949 5936 1973
GO:0032984 45 GO:0032984 macromolecular complex disassembly GOBP 259 -0.3528203 0.7027035 down 0.0000178 0.0005620 6175 51119 28973 64960 64432 51253 51081 29088 23107 55173 51021 7818 64965 51318 64969 84340 51650 54948 64975 324 6599 219927 64968 64963 64979 9645 54516 64949 81930
GO:0043241 45 GO:0043241 protein complex disassembly GOBP 247 -0.3482375 0.7059312 down 0.0000338 0.0010122 6175 51119 28973 64960 64432 51253 51081 29088 23107 55173 51021 7818 64965 51318 64969 84340 51650 54948 64975 324 6599 219927 64968 64963 64979 9645 54516 64949 81930
GO:0006413 45 GO:0006413 translational initiation GOBP 289 -0.3465451 0.7071270 down 0.0000415 0.0012207 6175 27335 1654 28973 64960 64432 51253 51081 29088 8664 23107 55173 51021 7818 64965 51318 64969 8891 51650 54948 64975 8890 219927 64968 64963 64979 1978 64949 5936 1973
GO:0022411 45 GO:0022411 cellular component disassembly GOBP 644 -0.2169350 0.8049823 down 0.0001217 0.0028818 6175 7416 4190 4715 54205 51119 5588 1508 3836 28973 64960 1351 64432 51253 10059 51081 29088 23107 55173 51021 7818 64965 23405 9131 23385 51318 64969 8428 84340 51650 54948 64975 324 5071 2021 51116 6599 6507 219927 3148 64968 64963 64979 28988 9645 149371 54516 649 9469 64949 80271 1302 100287171 55172 202374 10675 81930
GO:0006631 46 GO:0006631 fatty acid metabolic process GOBP 257 -0.5533241 0.5750352 down 0.0000000 0.0000000 5166 34 5164 1738 5565 5160 9261 5162 1892 10455 1737 6342 4706 1666 79602 2686 54704 5096 2181 7376 1632 30 4258 51102 11019 8879 2053 84693 5095 641371 22949 1571 1962 116285
GO:0032787 46 GO:0032787 monocarboxylic acid metabolic process GOBP 397 -0.4642846 0.6285846 down 0.0000000 0.0000000 7167 5166 2806 2821 34 5164 1738 5565 5160 9261 5162 1892 10455 1737 51660 3945 6342 5571 4706 1666 79602 9380 2686 54704 5096 2181 7376 1632 8659 30 4258 51102 957 6470 11019 8879 10873 55217 2053 84693 5095 641371 22949 1571 1962 8714 10675 116285
GO:0033108 47 GO:0033108 mitochondrial respiratory chain complex assembly GOBP 27 -1.0803332 0.3394824 down 0.0000000 0.0000000 4725 55245 4728 4724 9131 29090 6901 79133 55471 80224 90639
GO:0010257 47 GO:0010257 NADH dehydrogenase complex assembly GOBP 17 -1.1643678 0.3121199 down 0.0000000 0.0000002 4725 4728 4724 9131 29090 6901 79133 55471 80224
GO:0032981 47 GO:0032981 mitochondrial respiratory chain complex I assembly GOBP 17 -1.1643678 0.3121199 down 0.0000000 0.0000002 4725 4728 4724 9131 29090 6901 79133 55471 80224
GO:0097031 47 GO:0097031 mitochondrial respiratory chain complex I biogenesis GOBP 17 -1.1643678 0.3121199 down 0.0000000 0.0000002 4725 4728 4724 9131 29090 6901 79133 55471 80224
GO:0019752 48 GO:0019752 carboxylic acid metabolic process GOBP 814 -0.6063452 0.5453403 down 0.0000000 0.0000000 1158 7167 3418 50 1431 5166 4191 1160 2806 4967 23530 6389 2805 2821 34 5164 1738 5565 5160 6390 8803 5859 9261 8801 4947 1743 5162 1892 36 8802 10455 2271 4677 1737 51660 3945 6342 11112 51520 5571 4706 1666 79602 9380 4522 2686 54704 137872 6391 4329 493 51582 10295 5096 2181 2746 7376 376497 55526 1632 81579 8659 80222 5092 48 30 1152 4258 5188 2875 2730 51102 957 587 6470 6611 11019 10797 8879 10873 79731 55217 2053 84693 2639 5095 501 255189 64122 7263 594 125061 641371 22949 79896 1571 1962 89874 51268 55753 8714 10675 116285
GO:0007005 49 GO:0007005 mitochondrion organization GOBP 665 -0.5153284 0.5973044 down 0.0000000 0.0000000 506 291 7416 6648 9927 4719 4190 3313 4715 54205 10935 5565 140735 54927 400916 7284 4725 28973 64960 55245 1351 64432 5571 51253 4728 9093 4724 10059 51081 29088 53632 23107 55173 51021 10105 708 7818 26355 64965 30968 9131 51318 64969 23203 80222 29090 84340 51650 54948 10651 6832 64975 5071 92609 6901 23410 51116 5188 6507 219927 64968 64963 10102 79133 4899 64979 55471 92667 3954 80224 10018 54516 79017 9469 90639 64949 4285 578 79753 2066 80271 55172 51025 202374 10675 90506 1525
GO:0009060 50 GO:0009060 aerobic respiration GOBP 42 -1.4227367 0.2410534 down 0.0000000 0.0000000 3418 50 1431 4191 4967 7385 7381 23530 6389 7384 1738 5160 6390 8803 8801 1743 5162 8802 2271 7388 6391 55526 23410 10873 90639 9016 55753
GO:0072350 50 GO:0072350 tricarboxylic acid metabolic process GOBP 36 -1.3737672 0.2531515 down 0.0000000 0.0000000 3418 50 1431 4191 4967 23530 6389 1738 5160 6390 8803 8801 1743 5162 8802 2271 6391 2746 55526 48 55753
GO:0006099 50 GO:0006099 tricarboxylic acid cycle GOBP 25 -1.5535858 0.2114883 down 0.0000000 0.0000000 3418 50 1431 4191 4967 23530 6389 1738 5160 6390 8803 8801 1743 5162 8802 2271 6391 55526 55753
GO:0006101 50 GO:0006101 citrate metabolic process GOBP 30 -1.4181050 0.2421725 down 0.0000000 0.0000000 3418 50 1431 4191 4967 23530 6389 1738 5160 6390 8803 8801 1743 5162 8802 2271 6391 55526 48 55753