Number of significant go terms: 84
fit.cluster Concept.ID Concept.name ontology n.genes coeff odds.ratio status p.value FDR sig.genes
GO:0048864 1 GO:0048864 stem cell development GOBP 161 -0.4198567 0.6571410 down 0.0001299 0.0127566 6774 5430 10155 283149 51593 6497 4849 8324 2668 9314 123169 8313 54361 3037 25805 7849
GO:0019827 1 GO:0019827 stem cell maintenance GOBP 62 -0.5806486 0.5595354 down 0.0001404 0.0135006 6774 5430 51593 6497 4849 8324 9314 123169 7849
GO:0010608 1 GO:0010608 posttranscriptional regulation of gene expression GOBP 403 -0.2778855 0.7573836 down 0.0001657 0.0156073 1981 1983 3183 3920 3192 10658 23 2648 10492 7756 11261 3054 23645 51593 23515 10949 84271 192670 23560 55795 9811 51616 2668 4086 83759 51091 8313 66037 1734 5347 4487 51087
GO:0048863 1 GO:0048863 stem cell differentiation GOBP 204 -0.3416066 0.7106277 down 0.0007840 0.0436028 6774 5430 10155 6722 283149 51593 6497 4849 8324 2668 9314 123169 8313 54361 3037 25805 7849
GO:0006405 2 GO:0006405 RNA export from nucleus GOBP 89 -0.5786609 0.5606486 down 0.0000165 0.0030416 9877 10921 10482 6428 6429 11338 84271
GO:0006406 2 GO:0006406 mRNA export from nucleus GOBP 74 -0.5943914 0.5518983 down 0.0000302 0.0051695 9877 10921 10482 6428 6429 11338 84271
GO:0051028 2 GO:0051028 mRNA transport GOBP 76 -0.5696544 0.5657209 down 0.0000694 0.0082148 9877 10921 10482 6428 6429 11338 84271
GO:0006913 2 GO:0006913 nucleocytoplasmic transport GOBP 317 -0.2970151 0.7430328 down 0.0002101 0.0186537 3843 9670 9877 6774 10921 3725 10482 10155 6428 6429 11261 11338 10204 23189 84271 8086 8324 23636 23165 5514 8313 4968 10636 25805
GO:0050657 2 GO:0050657 nucleic acid transport GOBP 101 -0.4833724 0.6167001 down 0.0002571 0.0213214 9877 10921 10482 6428 6429 11338 84271
GO:0050658 2 GO:0050658 RNA transport GOBP 101 -0.4833724 0.6167001 down 0.0002571 0.0213214 9877 10921 10482 6428 6429 11338 84271
GO:0051236 2 GO:0051236 establishment of RNA localization GOBP 101 -0.4833724 0.6167001 down 0.0002571 0.0213214 9877 10921 10482 6428 6429 11338 84271
GO:0051169 2 GO:0051169 nuclear transport GOBP 320 -0.2906428 0.7477828 down 0.0002734 0.0217580 3843 9670 9877 6774 10921 3725 10482 10155 6428 6429 11261 11338 10204 23189 84271 8086 8324 23636 23165 5514 8313 4968 10636 25805
GO:0006403 2 GO:0006403 RNA localization GOBP 108 -0.4628334 0.6294975 down 0.0003158 0.0235140 9877 10921 10482 6428 6429 11338 84271 636
GO:0015931 2 GO:0015931 nucleobase-containing compound transport GOBP 128 -0.4327836 0.6487009 down 0.0003723 0.0251909 9877 2030 10921 10482 6428 6429 11338 84271 347734
GO:0042384 3 GO:0042384 cilium assembly GOBP 122 0.7307279 2.0765917 up 0.0000000 0.0000004 3983 51382 54874 1874 585 54777 57728 4218 80184 129880 79582 29070 6103 117177 92104 79989 200728 9001
GO:0044782 3 GO:0044782 cilium organization GOBP 137 0.7032806 2.0203699 up 0.0000000 0.0000006 3983 51382 54874 1874 585 54777 57728 4218 80184 129880 79582 29070 6103 117177 92104 79989 200728 9001
GO:0060271 3 GO:0060271 cilium morphogenesis GOBP 152 0.6406276 1.8976714 up 0.0000000 0.0000038 3983 51382 54874 1874 585 54777 79600 57728 4218 80184 129880 79582 29070 6103 117177 92104 79989 200728 9001
GO:0010927 3 GO:0010927 cellular component assembly involved in morphogenesis GOBP 168 0.5962342 1.8152699 up 0.0000000 0.0000061 3983 51382 54874 1874 585 54777 8506 57728 4218 80184 129880 79582 29070 6103 117177 92104 10529 79989 200728 9001
GO:0070925 3 GO:0070925 organelle assembly GOBP 362 0.3522844 1.4223130 up 0.0000055 0.0014185 3983 11273 57533 6386 6385 51382 54874 1874 585 54777 57728 4218 636 80184 129880 79582 1104 29070 6103 117177 92104 10529 5347 79989 200728 9001
GO:0030031 3 GO:0030031 cell projection assembly GOBP 243 0.3783063 1.4598100 up 0.0000434 0.0065872 3983 1012 9148 6386 23189 51382 54874 1874 382 54828 585 54777 26051 57728 4218 221178 80184 129880 79582 29070 6103 117177 92104 79989 200728 9001 4070
GO:1902679 4 GO:1902679 negative regulation of RNA biosynthetic process GOBP 834 -0.2191073 0.8032356 down 0.0000483 0.0069049 57326 6774 7071 3725 7067 10507 57659 10413 4841 10014 10155 5465 1487 9572 9759 6944 4799 84159 3054 10664 54623 10370 10608 3727 6497 23090 79813 10614 648 387893 64344 6015 2274 11278 1616 51616 22954 84678 10919 51720 9314 863 4783 9400 467 79618 7767 6478 4261 51588 6907 80014 1428 406 7481 59348 7695 10172 8365 29028 54361 5347 6911 57491 84733 57761 84174 2100 7025 4602 148979
GO:1903507 4 GO:1903507 negative regulation of nucleic acid-templated transcription GOBP 821 -0.2098319 0.8107205 down 0.0001134 0.0117910 57326 6774 7071 3725 7067 10507 57659 10413 4841 10014 10155 5465 1487 9572 9759 6944 4799 84159 3054 10664 54623 10370 10608 3727 6497 23090 79813 10614 648 387893 64344 6015 2274 11278 1616 51616 84678 10919 51720 9314 863 4783 9400 467 79618 7767 6478 4261 51588 6907 80014 1428 406 7481 59348 7695 10172 8365 29028 54361 5347 6911 57491 84733 57761 84174 2100 7025 4602 148979
GO:0045892 4 GO:0045892 negative regulation of transcription, DNA-templated GOBP 792 -0.2137673 0.8075362 down 0.0001149 0.0117910 57326 6774 7071 3725 7067 10507 57659 4841 10014 10155 5465 1487 9572 9759 6944 4799 84159 3054 10664 54623 10370 10608 3727 6497 23090 79813 10614 648 387893 6015 2274 11278 1616 51616 84678 10919 51720 9314 863 4783 9400 467 79618 7767 4261 51588 6907 80014 1428 406 7481 59348 7695 10172 8365 29028 54361 5347 6911 57491 84733 57761 84174 2100 7025 4602 148979
GO:0000122 4 GO:0000122 negative regulation of transcription from RNA polymerase II promoter GOBP 447 -0.2386799 0.7876670 down 0.0005675 0.0344655 6774 7071 3725 7067 10507 57659 10014 5465 1487 9572 9759 6944 4799 84159 3054 10664 54623 10370 10608 3727 6497 10614 648 387893 2274 11278 51616 84678 10919 9314 4783 9400 467 4261 6907 80014 1428 59348 7695 5347 6911 57491 84733 57761 84174 2100 7025 4602 148979
GO:0045333 5 GO:0045333 cellular respiration GOBP 182 0.5924794 1.8084668 up 0.0000001 0.0000624 55526 27109 27166 4843 55753
GO:0009083 5 GO:0009083 branched-chain amino acid catabolic process GOBP 26 1.1464703 3.1470650 up 0.0000004 0.0001585 1629 587 56922
GO:0042073 5 GO:0042073 intraciliary transport GOBP 25 1.0552923 2.8728146 up 0.0000018 0.0005411 57728 6103 92104 79989
GO:0009081 5 GO:0009081 branched-chain amino acid metabolic process GOBP 30 0.9651506 2.6251830 up 0.0000289 0.0051280 1629 587 56922
GO:0048147 5 GO:0048147 negative regulation of fibroblast proliferation GOBP 17 -0.9231550 0.3972637 down 0.0000413 0.0065872 23515 6497 22954
GO:0022900 5 GO:0022900 electron transport chain GOBP 134 0.5456695 1.7257633 up 0.0000551 0.0074761 27109
GO:0022904 5 GO:0022904 respiratory electron transport chain GOBP 132 0.5453611 1.7252312 up 0.0000608 0.0079670 27109
GO:0009063 5 GO:0009063 cellular amino acid catabolic process GOBP 101 0.5733989 1.7742875 up 0.0000625 0.0079670 23576 6821 1629 587 56922 10157 23564 56267 4843 10841 144193 1468
GO:0045948 5 GO:0045948 positive regulation of translational initiation GOBP 11 -1.0266959 0.3581885 down 0.0000654 0.0079670 23645 66037
GO:0042461 5 GO:0042461 photoreceptor cell development GOBP 11 1.1519715 3.1644253 up 0.0000799 0.0092250 585 80184 94137
GO:0045833 5 GO:0045833 negative regulation of lipid metabolic process GOBP 50 -0.6648933 0.5143284 down 0.0000909 0.0097533 54361 57761
GO:0009144 5 GO:0009144 purine nucleoside triphosphate metabolic process GOBP 122 0.5006026 1.6497150 up 0.0002081 0.0186537 131870 27109 63979
GO:0042278 5 GO:0042278 purine nucleoside metabolic process GOBP 180 0.4133764 1.5119140 up 0.0002587 0.0213214 4144 27109 347734 63979 27233 27232
GO:0045943 5 GO:0045943 positive regulation of transcription from RNA polymerase I promoter GOBP 12 -0.9485011 0.3873211 down 0.0002733 0.0217580 7343 23645
GO:0006415 5 GO:0006415 translational termination GOBP 171 0.3858876 1.4709193 up 0.0002834 0.0221755 6170 7818 28957
GO:0050909 5 GO:0050909 sensory perception of taste GOBP 12 -0.9920120 0.3708298 down 0.0003157 0.0235140 9311 41 80835
GO:0006099 5 GO:0006099 tricarboxylic acid cycle GOBP 25 0.8562333 2.3542762 up 0.0003266 0.0239270 55526 55753
GO:0046128 5 GO:0046128 purine ribonucleoside metabolic process GOBP 176 0.4098755 1.5066302 up 0.0003384 0.0243930 4144 27109 347734 63979 27233 27232
GO:0034616 5 GO:0034616 response to laminar fluid shear stress GOBP 12 -0.9599850 0.3828986 down 0.0003654 0.0251720 4780 9314 10365
GO:0006119 5 GO:0006119 oxidative phosphorylation GOBP 61 0.6009148 1.8237865 up 0.0003766 0.0251909
GO:0034377 5 GO:0034377 plasma lipoprotein particle assembly GOBP 10 -0.9835101 0.3739960 down 0.0003858 0.0254375 2181 5326
GO:0048261 5 GO:0048261 negative regulation of receptor-mediated endocytosis GOBP 10 -0.9769620 0.3764530 down 0.0004489 0.0290900 382 1742
GO:0006414 5 GO:0006414 translational elongation GOBP 183 0.3657918 1.4416551 up 0.0004537 0.0290900 6170 29904 7818 28957 51091 1734
GO:0009199 5 GO:0009199 ribonucleoside triphosphate metabolic process GOBP 120 0.4805548 1.6169713 up 0.0004860 0.0307293 27109 63979
GO:0009205 5 GO:0009205 purine ribonucleoside triphosphate metabolic process GOBP 118 0.4823019 1.6197987 up 0.0004928 0.0307427 27109 63979
GO:0019228 5 GO:0019228 neuronal action potential GOBP 16 0.9449879 2.5727822 up 0.0005090 0.0313278 6332 3737
GO:0046034 5 GO:0046034 ATP metabolic process GOBP 117 0.4754550 1.6087460 up 0.0006468 0.0382748 27109 63979
GO:0045598 5 GO:0045598 regulation of fat cell differentiation GOBP 56 -0.5400674 0.5827090 down 0.0007129 0.0409204 9572 406 284207 57761
GO:0030325 5 GO:0030325 adrenal gland development GOBP 6 -1.0971248 0.3338295 down 0.0007181 0.0409204 10370 7481 54361
GO:0035966 6 GO:0035966 response to topologically incorrect protein GOBP 143 -0.4981862 0.6076318 down 0.0000047 0.0013361 7009 11080 23645 4780 3301 6464 30827 871 5526 467 55432 9570 9797 54956 27113
GO:0006986 6 GO:0006986 response to unfolded protein GOBP 135 -0.5031020 0.6046521 down 0.0000070 0.0015306 7009 11080 23645 4780 3301 6464 30827 871 5526 467 55432 9570 9797 54956 27113
GO:0030968 6 GO:0030968 endoplasmic reticulum unfolded protein response GOBP 104 -0.5130958 0.5986394 down 0.0000494 0.0069049 7009 23645 4780 6464 30827 5526 467 55432 9570 9797 54956 27113
GO:0035967 6 GO:0035967 cellular response to topologically incorrect protein GOBP 114 -0.4860451 0.6150541 down 0.0000656 0.0079670 7009 23645 4780 6464 30827 5526 467 55432 9570 9797 54956 27113
GO:0034620 6 GO:0034620 cellular response to unfolded protein GOBP 107 -0.4932768 0.6106222 down 0.0000856 0.0096372 7009 23645 4780 6464 30827 5526 467 55432 9570 9797 54956 27113
GO:0032069 6 GO:0032069 regulation of nuclease activity GOBP 79 -0.5337695 0.5863904 down 0.0000902 0.0097533 7009 6464 30827 5526 467 9570 9797 54956
GO:0006987 6 GO:0006987 activation of signaling protein activity involved in unfolded protein response GOBP 68 -0.5474374 0.5784302 down 0.0001729 0.0159597 6464 30827 5526 467 9570 9797 54956
GO:0032075 6 GO:0032075 positive regulation of nuclease activity GOBP 72 -0.5199389 0.5945569 down 0.0002928 0.0225298 6464 30827 5526 467 9570 9797 54956
GO:0031124 7 GO:0031124 mRNA 3'-end processing GOBP 114 -0.5834565 0.5579664 down 0.0000013 0.0004395 1981 10921 79869 29101 6428 6429 9924 54623 11338 4849 9125 123169
GO:1903311 7 GO:1903311 regulation of mRNA metabolic process GOBP 85 -0.6116160 0.5424735 down 0.0000049 0.0013361 7009 10921 22985 6429 54623 11338 10898 123169 9704
GO:0050686 7 GO:0050686 negative regulation of mRNA processing GOBP 25 -0.8752078 0.4167754 down 0.0000064 0.0015306 7009 10921 22985 6429 11338
GO:0050684 7 GO:0050684 regulation of mRNA processing GOBP 75 -0.6303085 0.5324275 down 0.0000067 0.0015306 7009 10921 22985 6429 54623 11338 10898 123169
GO:0048025 7 GO:0048025 negative regulation of mRNA splicing, via spliceosome GOBP 14 -1.0270153 0.3580741 down 0.0000082 0.0017138 10921 22985 6429 11338
GO:1903312 7 GO:1903312 negative regulation of mRNA metabolic process GOBP 28 -0.8367166 0.4331303 down 0.0000089 0.0017849 7009 10921 22985 6429 11338 9704
GO:0031123 7 GO:0031123 RNA 3'-end processing GOBP 134 -0.5050621 0.6034681 down 0.0000135 0.0025894 1981 10921 79869 29101 6428 6429 9924 54623 11338 4849 9125 123169
GO:0048024 7 GO:0048024 regulation of mRNA splicing, via spliceosome GOBP 38 -0.7500339 0.4723505 down 0.0000441 0.0065872 10921 22985 6429 11338
GO:0043484 7 GO:0043484 regulation of RNA splicing GOBP 72 -0.5331548 0.5867510 down 0.0003435 0.0243930 6625 10921 5430 10658 22985 6429 11338 1196 4654
GO:0033119 7 GO:0033119 negative regulation of RNA splicing GOBP 18 -0.8313444 0.4354635 down 0.0003582 0.0250546 10921 22985 6429 11338
GO:0006369 7 GO:0006369 termination of RNA polymerase II transcription GOBP 46 -0.5873601 0.5557926 down 0.0006999 0.0408928 10921 79869 6428 6429 11338
GO:1902932 8 GO:1902932 positive regulation of alcohol biosynthetic process GOBP 13 -0.9939356 0.3701172 down 0.0000442 0.0065872 2181 2246 54361 3973
GO:0046890 8 GO:0046890 regulation of lipid biosynthetic process GOBP 78 -0.5412555 0.5820171 down 0.0001264 0.0126833 5565 23399 9572 2181 142891 2246 54361 57761
GO:0006091 8 GO:0006091 generation of precursor metabolites and energy GOBP 407 0.2698523 1.3097710 up 0.0005910 0.0354311 2778 5565 3098 5571 5465 3667 6844 9572 9759 55526 3099 4899 9481 27109 8660 27166 3709 3953 5836 5210 9254 4843 552 55753
GO:0046889 8 GO:0046889 positive regulation of lipid biosynthetic process GOBP 36 -0.6415387 0.5264817 down 0.0007387 0.0415862 23399 9572 2181 2246 54361
GO:1902930 8 GO:1902930 regulation of alcohol biosynthetic process GOBP 33 -0.6730404 0.5101551 down 0.0008216 0.0451478 2181 2246 54361 3973
GO:0006397 9 GO:0006397 mRNA processing GOBP 486 -0.5258278 0.5910658 down 0.0000000 0.0000000 1981 5093 7009 6625 3183 220988 3192 5094 10921 79869 4670 5430 10658 22985 29101 10492 8996 6428 6429 9924 3188 54623 11338 10949 10286 27339 24144 4849 55596 9125 51428 10898 10262 50628 123169 10073 28960
GO:0000375 9 GO:0000375 RNA splicing, via transesterification reactions GOBP 361 -0.5707088 0.5651248 down 0.0000000 0.0000000 5093 6625 3183 220988 3192 5094 10921 79869 4670 5430 10658 22985 10492 8996 6428 6429 8570 3188 11338 10949 10286 27339 24144 55596 51428 10262 50628 10073 28960
GO:0000377 9 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile GOBP 353 -0.5677526 0.5667978 down 0.0000000 0.0000000 5093 6625 3183 220988 3192 5094 10921 79869 4670 5430 10658 22985 10492 8996 6428 6429 3188 11338 10949 10286 27339 24144 55596 51428 10262 50628 10073 28960
GO:0000398 9 GO:0000398 mRNA splicing, via spliceosome GOBP 353 -0.5677526 0.5667978 down 0.0000000 0.0000000 5093 6625 3183 220988 3192 5094 10921 79869 4670 5430 10658 22985 10492 8996 6428 6429 3188 11338 10949 10286 27339 24144 55596 51428 10262 50628 10073 28960
GO:0008380 9 GO:0008380 RNA splicing GOBP 442 -0.4872991 0.6142833 down 0.0000000 0.0000001 5093 6625 3183 220988 3192 5094 10921 79869 4670 5430 10658 22985 10492 8996 6428 6429 8570 3188 11338 10949 10286 27339 24144 11066 55596 1196 51428 10262 4654 6100 50628 10081 10073 28960 56342
GO:0006396 9 GO:0006396 RNA processing GOBP 653 -0.3893025 0.6775293 down 0.0000000 0.0000007 1981 5093 7009 6625 3183 220988 3192 5094 10921 79869 4670 5430 10658 22985 29101 10492 8996 6428 6429 9924 8570 3188 54623 51593 11338 10949 10286 27339 192670 24144 104 11066 4849 55596 9125 1196 51428 79665 10898 10262 4654 4086 6100 50628 123169 10081 10073 28960 9704 636 56342
GO:0016071 9 GO:0016071 mRNA metabolic process GOBP 684 -0.3092769 0.7339775 down 0.0000011 0.0003981 1981 5093 7009 6625 3183 220988 3192 5094 10921 79869 4670 6170 5430 10658 22985 29101 10492 8996 6428 6429 9924 3188 5520 54623 131870 11338 10949 10286 27339 192670 24144 104 4849 55596 9125 51428 9811 23644 22894 10898 10262 80153 50628 123169 10073 28960 51690 9704