p_ACT_meta

p_ACT_meta is an R program that adjusts sets of up to 500 p-values from meta-analysis-based association tests between correlated SNPs for multiple testing, accounting for the correlation between tests.

Version 0.1 of P_ACT_meta is the beta version, made available before publication of the accompanying article.

The file p_ACT_meta distribution includes the following:

• README.txt: a description of how to run p_ACT_meta.R and proper input file formats
• p_ACT_meta.R: R program.
• Sample_files: A directory containing sample input and output files for a meta-analysis with two samples of individuals
• Sample_files_2s: A directory containing sample input and output files for a two-stage meta-analysis

Please use this citation in any publications:

Conneely K.N. and Boehnke, M. (2010) Meta-analysis of genetic association studies and adjustment for multiple testing of correlated SNPs and traits. In revision.

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Download Program Directly

p_ACT_meta_0.1.tar.gz