Installation: No installation is needed. The distribution is ready to use. Simply download the compressed file and unzip to some folder you remember. General Instruction: 1. Prepare the required input files following the tutorial. 2. Click the executable file (GWASGUI.exe for windows and GWASGUI for linux) to start the program. 3. For the first time you launch the program, you need to click "load data" button and following the instruction to load input files one by one. The fourth and fifth file is optional, if you don't have it, just click "cancel button" in the file selection dialog. The program will spend some time to reorganize the data depending on the size of the input files. You only need to do step 3 once unless some error occurs. 4. Click "browser data" button and the interface appears. Next time, you only need to click "browser data" button with loading data set again. That's it! Enjoy it. Instruction to browse sample files. 1. Download the sample files sample1.zip, unzip it to the folder where GWAS GUI locates or other places. 2. Start the program, click "Load data" button. 3. Follow the instruction to select result1.txt, snpinfo1.txt, traitinfo.txt from the fold sample1. 4. Click "browser data".