Global Lipids Genetics Consortium Results
Meta-Analysis Tables
The tables below summarize the results of the meta-analysis of variants genotyped using the exome array in 47,532 East Asian samples to test for association with HDL cholesterol, LDL cholesterol, total cholesterol and triglyceride levels.
Reference
Lu X, Peloso GM, Liu DJ, Wu Y, Zhang H, Li J, Tang CS, Dorajoo R, [many additional authors], Kathiresan S, Mohlke KL, Wu T, Sham PC, Gu D, Willer C. Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants contributing to lipid levels and coronary artery disease. Nat Genet (in press).
Result Files
EXOME CHIP META-ANALYSIS IN PRIMARILY EAST ASIANS (N= ~47,000)
LDL Cholesterol
HDL Cholesterol
Triglycerides
Total Cholesterol
EXOME CHIP META-ANALYSIS IN EUROPEANS (N= ~300,000) + EAST ASIANS (N= ~47,000)
LDL Cholesterol
HDL Cholesterol
Triglycerides
Total Cholesterol
Columns in Result Files
| Column Label | Description |
| SNP_hg18 | Marker name in build hg18. |
| SNP_hg19 | Marker name in build hg19. |
| rsid | Marker name in rsid format. |
| A1 | Effect allele. |
| A2 | Other allele. |
| Beta | Effect size. |
| SE | Standard Error for Beta. |
| N | The number of individuals analyzed for this marker. |
| P-value | P-value after doing genomic control. |
| Freq.A1.1000G.EAS | Frequency of allele A1 from 1000G EAS sample. |
Using our GLGC data in LocusZoom (http://csg.sph.umich.edu/locuszoom).
Please e-mail Goncalo Abecasis or
Cristen Willer with comments or
suggestions.
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