Departments of Anesthesiology and Biostatistics | University of Michigan

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Cancer PRSweb

Compare evaluated PRS models, inspect score-level performance, and follow results into PheWAS analyses.

Phecodes 153.2

Colon cancer

153.2 Neoplasms Both 150-159.99, 208-208.99

Start with these models

These rows keep nominally significant, warning-free models first and sort the retained set by the smallest preserved p-value. Use them as a starting comparison set, not a definitive ranking.

Model Cohort Method P value Top 1% effect Flags Links
Colon cancer
Cancer code, self-reported: colon cancer/sigmoid cancer (UKB GWAS (PHESANT)) 		MGI PRS-CS 9.8e-9 3.85
OR
nominal retained
detail
PheWAS
Colon cancer
Cancer code, self-reported: colon cancer/sigmoid cancer (UKB GWAS (PHESANT)) 		MGI Fixed threshold (5e-06) 2.4e-6 1.6
OR
nominal retained
detail
Colon cancer
Cancer code, self-reported: colon cancer/sigmoid cancer (UKB GWAS (PHESANT)) 		MGI lassosum 4.9e-6 1.17
OR
nominal retained
detail
PheWAS
Colon cancer
Cancer code, self-reported: colon cancer/sigmoid cancer (UKB GWAS (PHESANT)) 		MGI P&T 4.4e-5 1.6
OR
nominal retained
detail
PheWAS
Colon cancer
ICD-10 C18 Malignant neoplasm of colon 		MGI PRS-CS 8.9e-4 1.65
OR
nominal retained
detail
PheWAS
Colon cancer
ICD-10 C18 Malignant neoplasm of colon 		MGI lassosum 0.0011 1.4
OR
nominal retained
detail
PheWAS
Colon cancer
Cancer code, self-reported: colon cancer/sigmoid cancer (UKB GWAS (PHESANT)) 		MGI Fixed threshold (5e-05) 0.0044 0.729
OR
nominal retained
detail
Colon cancer
Malignant neoplasm of colon 		MGI lassosum 0.0064 0.757
OR
nominal retained
detail
PheWAS

All related PRS models (20)

Multiple rows can map to the same phecode because cohort and PRS construction method differ. The full list below remains an unranked jump list; use the filtered Scores table for side-by-side comparison.

Compare related models in Scores table
Open full related-model jump list

ICD mappings

ICD code Type Description Phenome
C18 ICD10CM Malignant neoplasm of colon MGI
C18.0 ICD10CM Malignant neoplasm of cecum MGI
C18.1 ICD10CM Malignant neoplasm of appendix MGI
C18.2 ICD10CM Malignant neoplasm of ascending colon MGI
C18.3 ICD10CM Malignant neoplasm of hepatic flexure MGI
C18.4 ICD10CM Malignant neoplasm of transverse colon MGI
C18.5 ICD10CM Malignant neoplasm of splenic flexure MGI
C18.6 ICD10CM Malignant neoplasm of descending colon MGI
C18.7 ICD10CM Malignant neoplasm of sigmoid colon MGI
C18.8 ICD10CM Malignant neoplasm of overlapping sites of colon MGI
C18.9 ICD10CM Malignant neoplasm of colon, unspecified MGI
C26.0 ICD10CM Malignant neoplasm of intestinal tract, part unspecified MGI
C7A.020 ICD10CM Malignant carcinoid tumor of the appendix MGI
C7A.021 ICD10CM Malignant carcinoid tumor of the cecum MGI
C7A.022 ICD10CM Malignant carcinoid tumor of the ascending colon MGI
C7A.023 ICD10CM Malignant carcinoid tumor of the transverse colon MGI
C7A.024 ICD10CM Malignant carcinoid tumor of the descending colon MGI
C7A.025 ICD10CM Malignant carcinoid tumor of the sigmoid colon MGI
C7A.029 ICD10CM Malignant carcinoid tumor of the large intestine, unspecified portion MGI
D01.0 ICD10CM Carcinoma in situ of colon MGI
153.0 ICD9CM Malignant neoplasm of hepatic flexure MGI
153.1 ICD9CM Malignant neoplasm of transverse colon MGI
153.2 ICD9CM Malignant neoplasm of descending colon MGI
153.3 ICD9CM Malignant neoplasm of sigmoid colon MGI
153.4 ICD9CM Malignant neoplasm of cecum MGI
153.5 ICD9CM Malignant neoplasm of appendix vermiformis MGI
153.6 ICD9CM Malignant neoplasm of ascending colon MGI
153.7 ICD9CM Malignant neoplasm of splenic flexure MGI
153.8 ICD9CM Malignant neoplasm of other specified sites of large intestine MGI
153.9 ICD9CM Malignant neoplasm of colon, unspecified site MGI
159.0 ICD9CM Malignant neoplasm of intestinal tract, part unspecified MGI
209.10 ICD9CM Malignant carcinoid tumor of the large intestine, unspecified portion MGI
209.11 ICD9CM Malignant carcinoid tumor of the appendix MGI
209.12 ICD9CM Malignant carcinoid tumor of the cecum MGI
209.13 ICD9CM Malignant carcinoid tumor of the ascending colon MGI
209.14 ICD9CM Malignant carcinoid tumor of the transverse colon MGI
209.15 ICD9CM Malignant carcinoid tumor of the descending colon MGI
209.16 ICD9CM Malignant carcinoid tumor of the sigmoid colon MGI
230.3 ICD9CM Carcinoma in situ of colon MGI
V10.05 ICD9CM Personal history of malignant neoplasm of large intestine MGI
C18.0 ICD10 C18.0 Caecum UKB
C18.1 ICD10 C18.1 Appendix UKB
C18.2 ICD10 C18.2 Ascending colon UKB
C18.3 ICD10 C18.3 Hepatic flexure UKB
C18.4 ICD10 C18.4 Transverse colon UKB
C18.5 ICD10 C18.5 Splenic flexure UKB
C18.6 ICD10 C18.6 Descending colon UKB
C18.7 ICD10 C18.7 Sigmoid colon UKB
C18.8 ICD10 C18.8 Overlapping lesion of colon UKB
C18.9 ICD10 C18.9 Colon, unspecified UKB
C26.0 ICD10 C26.0 Intestinal tract, part unspecified UKB
D01.0 ICD10 D01.0 Colon UKB
153 ICD9 153 Malignant neoplasm of colon UKB
153.0 ICD9 1530 Malignant neoplasm of colon, hepatic flexure UKB
153.1 ICD9 1531 Malignant neoplasm of transverse colon UKB
153.2 ICD9 1532 Malignant neoplasm of descending colon UKB
153.3 ICD9 1533 Malignant neoplasm of sigmoid colon UKB
153.4 ICD9 1534 Malignant neoplasm of caecum UKB
153.5 ICD9 1535 Malignant neoplasm of appendix UKB
153.6 ICD9 1536 Malignant neoplasm of ascending colon UKB
153.7 ICD9 1537 Malignant neoplasm of colon, splenic flexure UKB
153.8 ICD9 1538 Malignant neoplasm of colon, other UKB
153.9 ICD9 1539 Malignant neoplasm of colon, unspecified UKB
159.0 ICD9 1590 Malignant neoplasm of intestinal tract, part unspecified UKB
230.3 ICD9 2303 Carcinoma in situ of colon UKB
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