Malignant neoplasm of rectum, rectosigmoid junction, and anus
153.3
Neoplasms
Both
150-159.99, 208-208.99
Start with these models
These rows keep nominally significant, warning-free models first and sort the retained set by the smallest preserved p-value. Use them as a starting comparison set, not a definitive ranking.
| Model | Cohort | Method | P value | Top 1% effect | Flags | Links |
|---|---|---|---|---|---|---|
|
Malignant neoplasm of rectum, rectosigmoid junction, and anus
ICD-10 C19 Malignant neoplasm of rectosigmoid junction |
MGI | PRS-CS | 0.04 | 1.34 OR |
nominal
retained
|
detail PheWAS |
|
Malignant neoplasm of rectum, rectosigmoid junction, and anus
Malignant neoplasm of rectum |
MGI | PRS-CS | 0.048 | 1.02 OR |
nominal
retained
|
detail PheWAS |
All related PRS models (30)
Multiple rows can map to the same phecode because cohort and PRS construction method differ. The full list below remains an unranked jump list; use the filtered Scores table for side-by-side comparison.
Open full related-model jump list
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Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — Fixed threshold (5e-05)
ICD-10 C19 Malignant neoplasm of rectosigmoid junction -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — Fixed threshold (5e-05)
ICD-10 C21 Malignant neoplasm of anus and anal canal -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — Fixed threshold (5e-05)
Malignant neoplasm of anus and anal canal -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — Fixed threshold (5e-05)
Malignant neoplasm of rectum -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — Fixed threshold (5e-06)
ICD-10 C20 Malignant neoplasm of rectum -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — Fixed threshold (5e-06)
ICD-10 C21 Malignant neoplasm of anus and anal canal -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — Fixed threshold (5e-06)
Malignant neoplasm of rectum -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — Fixed threshold (5e-06)
Diagnoses - main ICD10: C21 Malignant neoplasm of anus and anal canal (UKB GWAS (ICD10)) -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — Fixed threshold (5e-07)
ICD-10 C21 Malignant neoplasm of anus and anal canal -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — P&T
ICD-10 C20 Malignant neoplasm of rectum -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — P&T
ICD-10 C21 Malignant neoplasm of anus and anal canal -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — P&T
Malignant neoplasm of rectosigmoid junction -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — P&T
Malignant neoplasm of rectum -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — P&T
Diagnoses - main ICD10: C21 Malignant neoplasm of anus and anal canal (UKB GWAS (ICD10)) -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — PRS-CS
Self-reported rectal cancer -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — PRS-CS
ICD-10 C19 Malignant neoplasm of rectosigmoid junction -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — PRS-CS
ICD-10 C20 Malignant neoplasm of rectum -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — PRS-CS
ICD-10 C21 Malignant neoplasm of anus and anal canal -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — PRS-CS
Malignant neoplasm of anus and anal canal -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — PRS-CS
Malignant neoplasm of rectosigmoid junction -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — PRS-CS
Malignant neoplasm of rectum -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — PRS-CS
Diagnoses - main ICD10: C21 Malignant neoplasm of anus and anal canal (UKB GWAS (ICD10)) -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — lassosum
Self-reported rectal cancer -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — lassosum
ICD-10 C19 Malignant neoplasm of rectosigmoid junction -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — lassosum
ICD-10 C20 Malignant neoplasm of rectum -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — lassosum
ICD-10 C21 Malignant neoplasm of anus and anal canal -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — lassosum
Malignant neoplasm of anus and anal canal -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — lassosum
Malignant neoplasm of rectosigmoid junction -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — lassosum
Malignant neoplasm of rectum -
Malignant neoplasm of rectum, rectosigmoid junction, and anus — MGI — lassosum
Diagnoses - main ICD10: C21 Malignant neoplasm of anus and anal canal (UKB GWAS (ICD10))
ICD mappings
| ICD code | Type | Description | Phenome |
|---|---|---|---|
| C19 | ICD10CM | Malignant neoplasm of rectosigmoid junction | MGI |
| C20 | ICD10CM | Malignant neoplasm of rectum | MGI |
| C21.0 | ICD10CM | Malignant neoplasm of anus, unspecified | MGI |
| C21.1 | ICD10CM | Malignant neoplasm of anal canal | MGI |
| C7A.026 | ICD10CM | Malignant carcinoid tumor of the rectum | MGI |
| D01.1 | ICD10CM | Carcinoma in situ of rectosigmoid junction | MGI |
| D01.2 | ICD10CM | Carcinoma in situ of rectum | MGI |
| D01.3 | ICD10CM | Carcinoma in situ of anus and anal canal | MGI |
| R85.610 | ICD10CM | Atypical squamous cells of undetermined significance on cytologic smear of anus (ASC-US) | MGI |
| R85.611 | ICD10CM | Atypical squamous cells cannot exclude high grade squamous intraepithelial lesion on cytologic smear of anus (ASC-H) | MGI |
| R85.612 | ICD10CM | Low grade squamous intraepithelial lesion on cytologic smear of anus (LGSIL) | MGI |
| R85.613 | ICD10CM | High grade squamous intraepithelial lesion on cytologic smear of anus (HGSIL) | MGI |
| R85.614 | ICD10CM | Cytologic evidence of malignancy on smear of anus | MGI |
| R85.619 | ICD10CM | Unspecified abnormal cytological findings in specimens from anus | MGI |
| 154.0 | ICD9CM | Malignant neoplasm of rectosigmoid junction | MGI |
| 154.1 | ICD9CM | Malignant neoplasm of rectum | MGI |
| 154.2 | ICD9CM | Malignant neoplasm of anal canal | MGI |
| 154.3 | ICD9CM | Malignant neoplasm of anus, unspecified site | MGI |
| 209.17 | ICD9CM | Malignant carcinoid tumor of the rectum | MGI |
| 230.4 | ICD9CM | Carcinoma in situ of rectum | MGI |
| 230.5 | ICD9CM | Carcinoma in situ of anal canal | MGI |
| 230.6 | ICD9CM | Carcinoma in situ of anus, unspecified | MGI |
| 796.70 | ICD9CM | Abnormal glandular Papanicolaou smear of anus | MGI |
| 796.71 | ICD9CM | Papanicolaou smear of anus with atypical squamous cells of undetermined significance (ASC-US) | MGI |
| 796.72 | ICD9CM | Papanicolaou smear of anus with atypical squamous cells cannot exclude high grade squamous intraepithelial lesion (ASC-H) | MGI |
| 796.73 | ICD9CM | Papanicolaou smear of anus with low grade squamous intraepithelial lesion (LGSIL) | MGI |
| 796.74 | ICD9CM | Papanicolaou smear of anus with high grade squamous intraepithelial lesion (HGSIL) | MGI |
| 796.76 | ICD9CM | Papanicolaou smear of anus with cytologic evidence of malignancy | MGI |
| V10.06 | ICD9CM | Personal history of malignant neoplasm of rectum, rectosigmoid junction, and anus | MGI |
| C19 | ICD10 | C19 Malignant neoplasm of rectosigmoid junction | UKB |
| C20 | ICD10 | C20 Malignant neoplasm of rectum | UKB |
| C21.0 | ICD10 | C21.0 Anus, unspecified | UKB |
| C21.1 | ICD10 | C21.1 Anal canal | UKB |
| D01.1 | ICD10 | D01.1 Rectosigmoid junction | UKB |
| D01.2 | ICD10 | D01.2 Rectum | UKB |
| D01.3 | ICD10 | D01.3 Anus and anal canal | UKB |
| 154 | ICD9 | 154 Malignant neoplasm of rectum, rectosigmoid junction and anus | UKB |
| 154.0 | ICD9 | 1540 Malignant neoplasm of rectosigmoid junction | UKB |
| 154.1 | ICD9 | 1541 Malignant neoplasm of rectum | UKB |
| 154.2 | ICD9 | 1542 Malignant neoplasm of anal canal | UKB |
| 154.3 | ICD9 | 1543 Malignant neoplasm of anus, unspecified | UKB |
| 230.4 | ICD9 | 2304 Carcinoma in situ of rectum | UKB |
| 230.5 | ICD9 | 2305 Carcinoma in situ of anal canal | UKB |
| 230.6 | ICD9 | 2306 Carcinoma in situ of anus, unspecified | UKB |