Departments of Anesthesiology and Biostatistics | University of Michigan

Polygenic risk score research portal

Cancer PRSweb

Compare evaluated PRS models, inspect score-level performance, and follow results into PheWAS analyses.

Phecodes 174.1

Breast cancer [female]

174.1 Neoplasms Female 174-184.99, 610-610.99

Start with these models

These rows keep nominally significant, warning-free models first and sort the retained set by the smallest preserved p-value. Use them as a starting comparison set, not a definitive ranking.

Model Cohort Method P value Top 1% effect Flags Links
Breast cancer [female]
Overall 		UKB PRS-CS 2.1e-364 4.38
OR
nominal retained
detail
PheWAS
Breast cancer [female]
Overall 		UKB lassosum 2.91e-325 4.02
OR
nominal retained
detail
PheWAS
Breast cancer [female]
ER positive 		UKB PRS-CS 1.12e-308 3.64
OR
nominal retained
detail
PheWAS
Breast cancer [female]
ER positive 		UKB lassosum 1.4e-274 3.86
OR
nominal retained
detail
PheWAS
Breast cancer [female]
Overall 		UKB Fixed threshold (5e-06) 1.5e-271 3.69
OR
nominal retained
detail
Breast cancer [female]
Overall 		UKB P&T 2.5e-270 3.32
OR
nominal retained
detail
PheWAS
Breast cancer [female]
Overall 		UKB Fixed threshold (5e-05) 7.1e-265 3.49
OR
nominal retained
detail
Breast cancer [female]
Overall 		UKB Fixed threshold (5e-07) 2.3e-260 3.81
OR
nominal retained
detail

All related PRS models (145)

Multiple rows can map to the same phecode because cohort and PRS construction method differ. The full list below remains an unranked jump list; use the filtered Scores table for side-by-side comparison.

Compare related models in Scores table
Open full related-model jump list

ICD mappings

ICD code Type Description Phenome
C50 ICD10CM Malignant neoplasm of breast MGI
C50.0 ICD10CM Malignant neoplasm of nipple and areola MGI
C50.01 ICD10CM Malignant neoplasm of nipple and areola, female MGI
C50.011 ICD10CM Malignant neoplasm of nipple and areola, right female breast MGI
C50.012 ICD10CM Malignant neoplasm of nipple and areola, left female breast MGI
C50.019 ICD10CM Malignant neoplasm of nipple and areola, unspecified female breast MGI
C50.02 ICD10CM Malignant neoplasm of nipple and areola, male MGI
C50.021 ICD10CM Malignant neoplasm of nipple and areola, right male breast MGI
C50.022 ICD10CM Malignant neoplasm of nipple and areola, left male breast MGI
C50.029 ICD10CM Malignant neoplasm of nipple and areola, unspecified male breast MGI
C50.1 ICD10CM Malignant neoplasm of central portion of breast MGI
C50.11 ICD10CM Malignant neoplasm of central portion of breast, female MGI
C50.111 ICD10CM Malignant neoplasm of central portion of right female breast MGI
C50.112 ICD10CM Malignant neoplasm of central portion of left female breast MGI
C50.119 ICD10CM Malignant neoplasm of central portion of unspecified female breast MGI
C50.12 ICD10CM Malignant neoplasm of central portion of breast, male MGI
C50.121 ICD10CM Malignant neoplasm of central portion of right male breast MGI
C50.122 ICD10CM Malignant neoplasm of central portion of left male breast MGI
C50.129 ICD10CM Malignant neoplasm of central portion of unspecified male breast MGI
C50.2 ICD10CM Malignant neoplasm of upper-inner quadrant of breast MGI
C50.21 ICD10CM Malignant neoplasm of upper-inner quadrant of breast, female MGI
C50.211 ICD10CM Malignant neoplasm of upper-inner quadrant of right female breast MGI
C50.212 ICD10CM Malignant neoplasm of upper-inner quadrant of left female breast MGI
C50.219 ICD10CM Malignant neoplasm of upper-inner quadrant of unspecified female breast MGI
C50.22 ICD10CM Malignant neoplasm of upper-inner quadrant of breast, male MGI
C50.221 ICD10CM Malignant neoplasm of upper-inner quadrant of right male breast MGI
C50.222 ICD10CM Malignant neoplasm of upper-inner quadrant of left male breast MGI
C50.229 ICD10CM Malignant neoplasm of upper-inner quadrant of unspecified male breast MGI
C50.3 ICD10CM Malignant neoplasm of lower-inner quadrant of breast MGI
C50.31 ICD10CM Malignant neoplasm of lower-inner quadrant of breast, female MGI
C50.311 ICD10CM Malignant neoplasm of lower-inner quadrant of right female breast MGI
C50.312 ICD10CM Malignant neoplasm of lower-inner quadrant of left female breast MGI
C50.319 ICD10CM Malignant neoplasm of lower-inner quadrant of unspecified female breast MGI
C50.32 ICD10CM Malignant neoplasm of lower-inner quadrant of breast, male MGI
C50.321 ICD10CM Malignant neoplasm of lower-inner quadrant of right male breast MGI
C50.322 ICD10CM Malignant neoplasm of lower-inner quadrant of left male breast MGI
C50.329 ICD10CM Malignant neoplasm of lower-inner quadrant of unspecified male breast MGI
C50.4 ICD10CM Malignant neoplasm of upper-outer quadrant of breast MGI
C50.41 ICD10CM Malignant neoplasm of upper-outer quadrant of breast, female MGI
C50.411 ICD10CM Malignant neoplasm of upper-outer quadrant of right female breast MGI
C50.412 ICD10CM Malignant neoplasm of upper-outer quadrant of left female breast MGI
C50.419 ICD10CM Malignant neoplasm of upper-outer quadrant of unspecified female breast MGI
C50.42 ICD10CM Malignant neoplasm of upper-outer quadrant of breast, male MGI
C50.421 ICD10CM Malignant neoplasm of upper-outer quadrant of right male breast MGI
C50.422 ICD10CM Malignant neoplasm of upper-outer quadrant of left male breast MGI
C50.429 ICD10CM Malignant neoplasm of upper-outer quadrant of unspecified male breast MGI
C50.5 ICD10CM Malignant neoplasm of lower-outer quadrant of breast MGI
C50.51 ICD10CM Malignant neoplasm of lower-outer quadrant of breast, female MGI
C50.511 ICD10CM Malignant neoplasm of lower-outer quadrant of right female breast MGI
C50.512 ICD10CM Malignant neoplasm of lower-outer quadrant of left female breast MGI
C50.519 ICD10CM Malignant neoplasm of lower-outer quadrant of unspecified female breast MGI
C50.52 ICD10CM Malignant neoplasm of lower-outer quadrant of breast, male MGI
C50.521 ICD10CM Malignant neoplasm of lower-outer quadrant of right male breast MGI
C50.522 ICD10CM Malignant neoplasm of lower-outer quadrant of left male breast MGI
C50.529 ICD10CM Malignant neoplasm of lower-outer quadrant of unspecified male breast MGI
C50.6 ICD10CM Malignant neoplasm of axillary tail of breast MGI
C50.61 ICD10CM Malignant neoplasm of axillary tail of breast, female MGI
C50.611 ICD10CM Malignant neoplasm of axillary tail of right female breast MGI
C50.612 ICD10CM Malignant neoplasm of axillary tail of left female breast MGI
C50.619 ICD10CM Malignant neoplasm of axillary tail of unspecified female breast MGI
C50.62 ICD10CM Malignant neoplasm of axillary tail of breast, male MGI
C50.621 ICD10CM Malignant neoplasm of axillary tail of right male breast MGI
C50.622 ICD10CM Malignant neoplasm of axillary tail of left male breast MGI
C50.629 ICD10CM Malignant neoplasm of axillary tail of unspecified male breast MGI
C50.8 ICD10CM Malignant neoplasm of overlapping sites of breast MGI
C50.81 ICD10CM Malignant neoplasm of overlapping sites of breast, female MGI
C50.811 ICD10CM Malignant neoplasm of overlapping sites of right female breast MGI
C50.812 ICD10CM Malignant neoplasm of overlapping sites of left female breast MGI
C50.819 ICD10CM Malignant neoplasm of overlapping sites of unspecified female breast MGI
C50.82 ICD10CM Malignant neoplasm of overlapping sites of breast, male MGI
C50.821 ICD10CM Malignant neoplasm of overlapping sites of right male breast MGI
C50.822 ICD10CM Malignant neoplasm of overlapping sites of left male breast MGI
C50.829 ICD10CM Malignant neoplasm of overlapping sites of unspecified male breast MGI
C50.9 ICD10CM Malignant neoplasm of breast of unspecified site MGI
C50.91 ICD10CM Malignant neoplasm of breast of unspecified site, female MGI
C50.911 ICD10CM Malignant neoplasm of unspecified site of right female breast MGI
C50.912 ICD10CM Malignant neoplasm of unspecified site of left female breast MGI
C50.919 ICD10CM Malignant neoplasm of unspecified site of unspecified female breast MGI
C50.92 ICD10CM Malignant neoplasm of breast of unspecified site, male MGI
C50.921 ICD10CM Malignant neoplasm of unspecified site of right male breast MGI
C50.922 ICD10CM Malignant neoplasm of unspecified site of left male breast MGI
C50.929 ICD10CM Malignant neoplasm of unspecified site of unspecified male breast MGI
D05 ICD10CM Carcinoma in situ of breast MGI
D05.0 ICD10CM Lobular carcinoma in situ of breast MGI
D05.00 ICD10CM Lobular carcinoma in situ of unspecified breast MGI
D05.01 ICD10CM Lobular carcinoma in situ of right breast MGI
D05.02 ICD10CM Lobular carcinoma in situ of left breast MGI
D05.1 ICD10CM Intraductal carcinoma in situ of breast MGI
D05.10 ICD10CM Intraductal carcinoma in situ of unspecified breast MGI
D05.11 ICD10CM Intraductal carcinoma in situ of right breast MGI
D05.12 ICD10CM Intraductal carcinoma in situ of left breast MGI
D05.8 ICD10CM Other specified type of carcinoma in situ of breast MGI
D05.80 ICD10CM Other specified type of carcinoma in situ of unspecified breast MGI
D05.81 ICD10CM Other specified type of carcinoma in situ of right breast MGI
D05.82 ICD10CM Other specified type of carcinoma in situ of left breast MGI
D05.9 ICD10CM Unspecified type of carcinoma in situ of breast MGI
D05.90 ICD10CM Unspecified type of carcinoma in situ of unspecified breast MGI
D05.91 ICD10CM Unspecified type of carcinoma in situ of right breast MGI
D05.92 ICD10CM Unspecified type of carcinoma in situ of left breast MGI
174.0 ICD9CM Malignant neoplasm of nipple and areola of female breast MGI
174.1 ICD9CM Malignant neoplasm of central portion of female breast MGI
174.2 ICD9CM Malignant neoplasm of upper-inner quadrant of female breast MGI
174.3 ICD9CM Malignant neoplasm of lower-inner quadrant of female breast MGI
174.4 ICD9CM Malignant neoplasm of upper-outer quadrant of female breast MGI
174.5 ICD9CM Malignant neoplasm of lower-outer quadrant of female breast MGI
174.6 ICD9CM Malignant neoplasm of axillary tail of female breast MGI
174.8 ICD9CM Malignant neoplasm of other specified sites of female breast MGI
174.9 ICD9CM Malignant neoplasm of breast (female), unspecified MGI
233.0 ICD9CM Carcinoma in situ of breast MGI
V10.3 ICD9CM Personal history of malignant neoplasm of breast MGI
C50.0 ICD10 C50.0 Nipple and areola UKB
C50.1 ICD10 C50.1 Central portion of breast UKB
C50.2 ICD10 C50.2 Upper-inner quadrant of breast UKB
C50.3 ICD10 C50.3 Lower-inner quadrant of breast UKB
C50.4 ICD10 C50.4 Upper-outer quadrant of breast UKB
C50.5 ICD10 C50.5 Lower-outer quadrant of breast UKB
C50.6 ICD10 C50.6 Axillary tail of breast UKB
C50.8 ICD10 C50.8 Overlapping lesion of breast UKB
C50.9 ICD10 C50.9 Breast, unspecified UKB
D05.1 ICD10 D05.1 Intraductal carcinoma in situ UKB
D05.7 ICD10 D05.7 Other carcinoma in situ of breast UKB
D05.9 ICD10 D05.9 Carcinoma in situ of breast, unspecified UKB
Z85.3 ICD10 Z85.3 Personal history of malignant neoplasm of breast UKB
233.0 ICD9 2330 Carcinoma in situ of breast UKB
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