Departments of Anesthesiology and Biostatistics | University of Michigan

Start with these models

These rows keep nominally significant, warning-free models first and sort the retained set by the smallest preserved p-value. Use them as a starting comparison set, not a definitive ranking.

Model Cohort Method P value Top 1% effect Flags Links
Cancer of brain and nervous system
Glioma;Non-glioblastoma glioma;Glioma (high-grade)
UKB Fixed threshold (5e-07) 2.9e-15 3.29
OR
nominal retained
detail
Cancer of brain and nervous system
Glioma;Non-glioblastoma glioma;Glioma (high-grade)
UKB Fixed threshold (5e-05) 5.6e-15 3.65
OR
nominal retained
detail
Cancer of brain and nervous system
Glioma;Non-glioblastoma glioma;Glioma (high-grade)
UKB Fixed threshold (5e-06) 5.6e-15 3.65
OR
nominal retained
detail
Cancer of brain and nervous system
Glioma;Non-glioblastoma glioma;Glioma (high-grade)
UKB P&T 1.3e-14 2.93
OR
nominal retained
detail
PheWAS
Cancer of brain and nervous system
Glioma;Non-glioblastoma glioma;Glioma (high-grade)
UKB GWAS Hits 1.4e-14 3.64
OR
nominal retained
detail
PheWAS
Cancer of brain and nervous system
Glioma;Non-glioblastoma glioma;Glioma (high-grade)
UKB Fixed threshold (5e-09) 3.8e-14 3.64
OR
nominal retained
detail
Cancer of brain and nervous system
Glioma;Non-glioblastoma glioma;Glioma (high-grade) (GWAS Catalog (2019-05-03))
MGI Fixed threshold (5e-06) 0.015 1.22
OR
nominal retained
detail

All related PRS models (18)

Multiple rows can map to the same phecode because cohort and PRS construction method differ. The full list below remains an unranked jump list; use the filtered Scores table for side-by-side comparison.

Open full related-model jump list

ICD mappings

ICD code Type Description Phenome
C70 ICD10CM Malignant neoplasm of meninges MGI
C70.0 ICD10CM Malignant neoplasm of cerebral meninges MGI
C70.1 ICD10CM Malignant neoplasm of spinal meninges MGI
C70.9 ICD10CM Malignant neoplasm of meninges, unspecified MGI
C71 ICD10CM Malignant neoplasm of brain MGI
C71.0 ICD10CM Malignant neoplasm of cerebrum, except lobes and ventricles MGI
C71.1 ICD10CM Malignant neoplasm of frontal lobe MGI
C71.2 ICD10CM Malignant neoplasm of temporal lobe MGI
C71.3 ICD10CM Malignant neoplasm of parietal lobe MGI
C71.4 ICD10CM Malignant neoplasm of occipital lobe MGI
C71.5 ICD10CM Malignant neoplasm of cerebral ventricle MGI
C71.6 ICD10CM Malignant neoplasm of cerebellum MGI
C71.7 ICD10CM Malignant neoplasm of brain stem MGI
C71.8 ICD10CM Malignant neoplasm of overlapping sites of brain MGI
C71.9 ICD10CM Malignant neoplasm of brain, unspecified MGI
C72 ICD10CM Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system MGI
C72.0 ICD10CM Malignant neoplasm of spinal cord MGI
C72.1 ICD10CM Malignant neoplasm of cauda equina MGI
C72.2 ICD10CM Malignant neoplasm of olfactory nerve MGI
C72.20 ICD10CM Malignant neoplasm of unspecified olfactory nerve MGI
C72.21 ICD10CM Malignant neoplasm of right olfactory nerve MGI
C72.22 ICD10CM Malignant neoplasm of left olfactory nerve MGI
C72.3 ICD10CM Malignant neoplasm of optic nerve MGI
C72.30 ICD10CM Malignant neoplasm of unspecified optic nerve MGI
C72.31 ICD10CM Malignant neoplasm of right optic nerve MGI
C72.32 ICD10CM Malignant neoplasm of left optic nerve MGI
C72.4 ICD10CM Malignant neoplasm of acoustic nerve MGI
C72.40 ICD10CM Malignant neoplasm of unspecified acoustic nerve MGI
C72.41 ICD10CM Malignant neoplasm of right acoustic nerve MGI
C72.42 ICD10CM Malignant neoplasm of left acoustic nerve MGI
C72.5 ICD10CM Malignant neoplasm of other and unspecified cranial nerves MGI
C72.50 ICD10CM Malignant neoplasm of unspecified cranial nerve MGI
C72.59 ICD10CM Malignant neoplasm of other cranial nerves MGI
C72.9 ICD10CM Malignant neoplasm of central nervous system, unspecified MGI
191.0 ICD9CM Malignant neoplasm of cerebrum, except lobes and ventricles MGI
191.1 ICD9CM Malignant neoplasm of frontal lobe MGI
191.2 ICD9CM Malignant neoplasm of temporal lobe MGI
191.3 ICD9CM Malignant neoplasm of parietal lobe MGI
191.4 ICD9CM Malignant neoplasm of occipital lobe MGI
191.5 ICD9CM Malignant neoplasm of ventricles MGI
191.6 ICD9CM Malignant neoplasm of cerebellum nos MGI
191.7 ICD9CM Malignant neoplasm of brain stem MGI
191.8 ICD9CM Malignant neoplasm of other parts of brain MGI
191.9 ICD9CM Malignant neoplasm of brain, unspecified MGI
192.0 ICD9CM Malignant neoplasm of cranial nerves MGI
192.1 ICD9CM Malignant neoplasm of cerebral meninges MGI
192.2 ICD9CM Malignant neoplasm of spinal cord MGI
192.3 ICD9CM Malignant neoplasm of spinal meninges MGI
192.8 ICD9CM Malignant neoplasm of other specified sites of nervous system MGI
192.9 ICD9CM Malignant neoplasm of nervous system, part unspecified MGI
V10.85 ICD9CM Personal history of malignant neoplasm of brain MGI
V10.86 ICD9CM Personal history of malignant neoplasm of other parts of nervous system MGI
C70.0 ICD10 C70.0 Cerebral meninges UKB
C70.1 ICD10 C70.1 Spinal meninges UKB
C70.9 ICD10 C70.9 Meninges, unspecified UKB
C71.0 ICD10 C71.0 Cerebrum, except lobes and ventricles UKB
C71.1 ICD10 C71.1 Frontal lobe UKB
C71.2 ICD10 C71.2 Temporal lobe UKB
C71.3 ICD10 C71.3 Parietal lobe UKB
C71.4 ICD10 C71.4 Occipital lobe UKB
C71.5 ICD10 C71.5 Cerebral ventricle UKB
C71.6 ICD10 C71.6 Cerebellum UKB
C71.7 ICD10 C71.7 Brain stem UKB
C71.8 ICD10 C71.8 Overlapping lesion of brain UKB
C71.9 ICD10 C71.9 Brain, unspecified UKB
C72.0 ICD10 C72.0 Spinal cord UKB
C72.1 ICD10 C72.1 Cauda equina UKB
C72.2 ICD10 C72.2 Olfactory nerve UKB
C72.3 ICD10 C72.3 Optic nerve UKB
C72.4 ICD10 C72.4 Acoustic nerve UKB
C72.5 ICD10 C72.5 Other and unspecified cranial nerves UKB
C72.8 ICD10 C72.8 Overlapping lesion of brain and other parts of central nervous system UKB
C72.9 ICD10 C72.9 Central nervous system, unspecified UKB
192 ICD9 192 Malignant neoplasm of other and unspecified parts of nervous system UKB
192.0 ICD9 1920 Malignant neoplasm of cranial nerves UKB
192.1 ICD9 1921 Malignant neoplasm of cerebral meninges UKB
192.2 ICD9 1922 Malignant neoplasm of spinal cord UKB
192.3 ICD9 1923 Malignant neoplasm of spinal meninges UKB
192.8 ICD9 1928 Malignant neoplasm of nervous system (central), other UKB
192.9 ICD9 1929 Malignant neoplasm of nervous system (central), part unspecified UKB
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