Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Squamous cell carcinoma UK Biobank (UKB) PheWAS analysis

Squamous cell carcinoma — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID prsweb-phecode172-22-cscc-chahal-p-5e-08-ukb-20200608Legacy P_5e-08GWAS HitsChahal HS et al. 2018

Evaluation cohort: UK Biobank (UKB).

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249 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.01 0.992 – 1.04 0.223 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.01 0.975 – 1.06 0.474 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.07 0.987 – 1.16 0.1 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 1.01 0.94 – 1.08 0.81 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.21 0.931 – 1.58 0.152 55 550 all phecode
010 Tuberculosis Infectious Diseases 0.929 0.789 – 1.09 0.377 166 1659 all phecode
038 Septicemia Infectious Diseases 1.02 0.986 – 1.05 0.282 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.04 0.969 – 1.12 0.277 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 0.987 0.898 – 1.08 0.788 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 1.01 0.991 – 1.03 0.293 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.03 0.996 – 1.07 0.0837 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 0.989 0.939 – 1.04 0.671 1641 16433 all phecode
041.4 E. coli Infectious Diseases 1 0.962 – 1.04 0.945 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 0.962 0.868 – 1.07 0.469 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1 0.809 – 1.24 0.991 95 949 all phecode
054 Herpes simplex Infectious Diseases 1.1 0.962 – 1.27 0.161 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 1.08 0.991 – 1.17 0.0822 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 0.881 0.683 – 1.14 0.331 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.15 0.968 – 1.36 0.112 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.11 0.973 – 1.25 0.123 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 0.995 0.877 – 1.13 0.935 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.04 0.945 – 1.15 0.411 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.05 0.887 – 1.24 0.585 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.09 0.906 – 1.31 0.367 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 1.09 1.02 – 1.16 0.00793 1004 10036 all phecode
079 Viral infection Infectious Diseases 1 0.965 – 1.04 0.854 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 1.01 0.788 – 1.29 0.957 64 640 all phecode
080 Postoperative infection Infectious Diseases 1.02 0.992 – 1.05 0.152 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.05 1.01 – 1.09 0.0251 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.19 0.946 – 1.5 0.137 71 709 all phecode
1000 Burns Injuries & Poisonings 0.981 0.9 – 1.07 0.659 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 1.06 1 – 1.13 0.0434 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 0.999 0.971 – 1.03 0.934 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.04 0.927 – 1.18 0.476 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 1.01 0.955 – 1.07 0.75 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 0.956 0.839 – 1.09 0.492 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 1.03 0.901 – 1.17 0.698 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.03 0.967 – 1.1 0.344 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 1.02 0.996 – 1.04 0.114 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 1.01 0.988 – 1.04 0.285 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.01 0.987 – 1.03 0.421 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 1.01 0.831 – 1.22 0.932 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.01 0.896 – 1.13 0.899 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.04 0.809 – 1.35 0.743 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 1.01 0.981 – 1.05 0.453 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.01 0.993 – 1.03 0.245 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.915 0.807 – 1.04 0.165 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 0.91 0.802 – 1.03 0.144 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.12 0.891 – 1.41 0.33 74 756 all phecode
110.12 Althete's foot Infectious Diseases 0.81 0.678 – 0.969 0.021 141 1410 all phecode
112 Candidiasis Infectious Diseases 1.04 0.992 – 1.08 0.11 2126 21275 all phecode
117 Mycoses Infectious Diseases 0.916 0.806 – 1.04 0.183 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 0.882 0.746 – 1.04 0.138 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 0.89 0.7 – 1.13 0.341 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 1.05 0.816 – 1.36 0.696 69 689 all phecode
134 Helminthiases Infectious Diseases 1.17 0.981 – 1.4 0.0813 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.16 0.96 – 1.39 0.125 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.998 0.863 – 1.15 0.982 205 2050 all phecode
145 Cancer of mouth Neoplasms 1.02 0.944 – 1.11 0.578 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 0.888 0.789 – 0.999 0.0479 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.16 0.948 – 1.41 0.152 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.08 0.83 – 1.4 0.568 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.02 0.943 – 1.11 0.584 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 0.965 0.844 – 1.1 0.607 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 1.1 0.973 – 1.24 0.131 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 1.16 0.884 – 1.54 0.279 57 570 all phecode
150 Cancer of esophagus Neoplasms 0.978 0.907 – 1.05 0.565 762 7630 all phecode
151 Cancer of stomach Neoplasms 0.929 0.85 – 1.02 0.106 569 5696 all phecode
153 Colorectal cancer Neoplasms 0.998 0.968 – 1.03 0.891 4580 45799 all phecode
153.2 Colon cancer Neoplasms 1.01 0.969 – 1.04 0.773 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.999 0.956 – 1.05 0.979 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.992 0.894 – 1.1 0.881 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.09 0.925 – 1.29 0.299 158 1580 all phecode
157 Pancreatic cancer Neoplasms 0.964 0.888 – 1.05 0.386 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.02 0.96 – 1.09 0.491 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.997 0.969 – 1.03 0.824 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.04 0.893 – 1.21 0.631 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.854 0.736 – 0.991 0.0371 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.02 0.881 – 1.19 0.756 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 1.31 1.01 – 1.71 0.0414 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 1.05 1.01 – 1.1 0.00779 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.05 1.01 – 1.1 0.0209 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 1.08 0.982 – 1.19 0.11 437 4364 all phecode
170.1 Bone cancer Neoplasms 1.19 0.997 – 1.42 0.0542 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 1.05 0.941 – 1.18 0.368 331 3303 all phecode
172 Skin cancer Neoplasms 1.32 1.29 – 1.34 1.51e-215 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.33 1.28 – 1.38 1.27e-47 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 1.33 1.28 – 1.38 1.07e-47 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1.32 1.3 – 1.35 1.13e-183 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.53 1.42 – 1.66 3.64e-27 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.18 1.01 – 1.37 0.0323 181 1818 all phecode
174 Breast cancer Neoplasms 1.02 0.997 – 1.03 0.106 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 1.02 0.997 – 1.04 0.095 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.02 0.999 – 1.04 0.0704 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.966 0.793 – 1.18 0.731 115 1148 all phecode
175 Acquired absence of breast Neoplasms 1.02 0.977 – 1.06 0.373 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 0.997 0.953 – 1.04 0.882 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 0.982 0.866 – 1.11 0.784 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.998 0.953 – 1.04 0.926 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 0.97 0.915 – 1.03 0.303 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 1.03 0.971 – 1.09 0.35 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.06 0.993 – 1.13 0.0806 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.05 0.984 – 1.13 0.136 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.962 0.854 – 1.08 0.525 305 3049 all phecode
185 Cancer of prostate Neoplasms 1 0.973 – 1.03 0.998 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 0.994 0.902 – 1.09 0.896 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.989 0.778 – 1.26 0.928 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 1.04 0.923 – 1.17 0.522 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.986 0.811 – 1.2 0.887 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.01 0.978 – 1.04 0.546 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1 0.941 – 1.07 0.932 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.994 0.931 – 1.06 0.857 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.15 0.895 – 1.47 0.28 66 660 all phecode
189.2 Cancer of bladder Neoplasms 1.03 0.984 – 1.07 0.228 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.01 0.964 – 1.06 0.689 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.06 0.894 – 1.26 0.503 144 1439 all phecode
190 Cancer of eye Neoplasms 1.24 1.07 – 1.43 0.00442 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.03 0.952 – 1.12 0.461 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1.02 0.939 – 1.12 0.579 566 5650 all phecode
191.11 Cancer of brain Neoplasms 1.02 0.934 – 1.12 0.627 525 5240 all phecode
193 Thyroid cancer Neoplasms 1.06 0.947 – 1.18 0.326 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 0.974 0.785 – 1.21 0.809 95 949 all phecode
195 Cancer, suspected or other Neoplasms 1.08 1.06 – 1.1 2.38e-22 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.08 1.07 – 1.1 2.16e-22 16267 159497 all phecode
197 Chemotherapy Neoplasms 1.03 1.02 – 1.04 5.6e-05 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 1.03 1.01 – 1.05 0.0155 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.04 1.01 – 1.07 0.0128 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.03 0.984 – 1.07 0.21 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1 0.951 – 1.06 0.916 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.03 0.989 – 1.07 0.151 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.06 0.988 – 1.14 0.105 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.02 0.977 – 1.07 0.339 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.23 1.06 – 1.42 0.00527 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.02 0.963 – 1.07 0.541 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 0.832 0.662 – 1.05 0.114 95 950 all phecode
200 Myeloproliferative disease Neoplasms 1.02 0.956 – 1.09 0.537 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 1.01 0.913 – 1.13 0.786 387 3867 all phecode
201 Hodgkin's disease Neoplasms 1.04 0.917 – 1.18 0.53 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.02 0.978 – 1.07 0.333 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.03 0.985 – 1.09 0.179 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 0.956 0.855 – 1.07 0.433 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 1.06 0.97 – 1.15 0.207 581 5824 all phecode
204 Leukemia Neoplasms 1.04 0.988 – 1.09 0.134 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 1.07 0.988 – 1.17 0.095 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.924 0.691 – 1.23 0.592 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.09 1 – 1.2 0.0508 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 0.977 0.886 – 1.08 0.638 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 1.01 0.904 – 1.14 0.807 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.95 0.799 – 1.13 0.565 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 1.12 1.03 – 1.23 0.00948 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 1.03 1.02 – 1.05 2.57e-05 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.02 0.957 – 1.09 0.511 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.04 1.01 – 1.07 0.0141 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.969 0.865 – 1.09 0.584 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.14 1.02 – 1.28 0.0242 318 3187 all phecode
214 Lipoma Neoplasms 1.01 0.979 – 1.03 0.704 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1 0.971 – 1.03 0.937 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.01 0.95 – 1.08 0.714 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 0.954 0.931 – 0.977 0.00012 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.06 0.979 – 1.15 0.146 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.07 0.98 – 1.16 0.138 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 0.992 0.972 – 1.01 0.478 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 1 0.983 – 1.02 0.741 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.897 0.798 – 1.01 0.0674 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 1.06 1 – 1.12 0.0414 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.03 0.894 – 1.18 0.7 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.869 0.733 – 1.03 0.105 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.949 0.81 – 1.11 0.512 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 1.21 1.01 – 1.43 0.0335 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.38 1.09 – 1.74 0.00818 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.994 0.924 – 1.07 0.875 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.995 0.922 – 1.07 0.886 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.01 0.779 – 1.31 0.943 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.08 0.956 – 1.23 0.208 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.01 0.944 – 1.09 0.703 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.11 0.954 – 1.29 0.178 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.05 0.942 – 1.17 0.386 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.957 0.85 – 1.08 0.469 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.03 0.982 – 1.09 0.197 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.848 0.811 – 0.886 2.63e-13 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.951 0.872 – 1.04 0.26 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.01 0.949 – 1.08 0.758 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.956 0.869 – 1.05 0.357 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.08 0.993 – 1.16 0.0736 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.03 0.983 – 1.08 0.207 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 1.01 0.919 – 1.11 0.82 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.19 0.974 – 1.45 0.0891 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.03 0.862 – 1.23 0.743 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 1.02 1 – 1.04 0.0265 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.01 0.95 – 1.08 0.741 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.07 0.872 – 1.32 0.51 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.02 1 – 1.04 0.024 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 1 0.884 – 1.13 0.997 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.04 0.901 – 1.19 0.621 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.02 0.887 – 1.18 0.745 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.01 0.914 – 1.12 0.796 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.02 1.01 – 1.04 0.00155 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.04 0.997 – 1.08 0.0692 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.06 0.933 – 1.21 0.353 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.07 0.847 – 1.36 0.56 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.998 0.906 – 1.1 0.968 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.07 0.911 – 1.26 0.4 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.02 1.01 – 1.04 0.00443 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.12 0.929 – 1.36 0.229 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.02 0.882 – 1.18 0.793 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.01 0.944 – 1.08 0.79 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.03 0.935 – 1.12 0.596 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1 0.928 – 1.09 0.909 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.04 0.916 – 1.18 0.543 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.988 0.893 – 1.09 0.823 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.958 0.796 – 1.15 0.647 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.02 0.916 – 1.15 0.679 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.99 0.934 – 1.05 0.734 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.07 0.997 – 1.14 0.0601 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1 0.933 – 1.07 0.984 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.989 0.918 – 1.07 0.765 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.955 0.8 – 1.14 0.606 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1 0.923 – 1.08 0.993 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.912 0.781 – 1.06 0.242 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.01 0.815 – 1.25 0.946 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.09 0.96 – 1.24 0.184 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.1 0.885 – 1.37 0.389 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.02 0.864 – 1.2 0.816 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.923 0.85 – 1 0.0579 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.09 0.936 – 1.27 0.272 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.04 0.851 – 1.27 0.699 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.22 0.971 – 1.53 0.0876 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.871 0.781 – 0.972 0.0135 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.871 0.78 – 0.972 0.0133 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 0.947 0.827 – 1.09 0.438 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.903 0.78 – 1.05 0.173 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 1.22 1.04 – 1.44 0.0171 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.19 1 – 1.4 0.0446 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.956 0.782 – 1.17 0.66 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.16 0.985 – 1.37 0.0744 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.05 0.916 – 1.21 0.471 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 0.839 0.626 – 1.12 0.24 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 1.05 0.979 – 1.13 0.169 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.04 0.976 – 1.1 0.252 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.04 0.962 – 1.12 0.343 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.02 0.921 – 1.12 0.755 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.9 0.715 – 1.13 0.368 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.03 0.903 – 1.18 0.645 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 1.09 0.977 – 1.22 0.121 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.12 0.997 – 1.26 0.0557 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.09 0.964 – 1.24 0.165 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.12 0.966 – 1.29 0.136 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.09 0.898 – 1.33 0.379 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.996 0.779 – 1.27 0.973 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.921 0.776 – 1.09 0.346 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.909 0.756 – 1.09 0.306 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.01 1 – 1.02 0.0436 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.01 1 – 1.02 0.0485 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.01 0.998 – 1.02 0.101 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.15 0.875 – 1.5 0.323 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.951 0.809 – 1.12 0.542 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.1 0.947 – 1.27 0.218 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1 0.971 – 1.04 0.781 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 1 0.966 – 1.04 0.885 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.04 0.859 – 1.26 0.678 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.02 0.938 – 1.11 0.636 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.03 0.944 – 1.13 0.495 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.06 1.01 – 1.11 0.0148 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 1.06 0.981 – 1.15 0.138 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.12 1 – 1.24 0.0401 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.07 1 – 1.13 0.0363 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.15 0.984 – 1.35 0.0778 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.03 1.01 – 1.06 0.0137 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.02 0.986 – 1.05 0.278 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.996 0.873 – 1.14 0.954 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.02 0.975 – 1.07 0.347 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.06 0.991 – 1.13 0.0885 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.01 0.955 – 1.07 0.747 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.03 0.972 – 1.1 0.296 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 1.05 0.981 – 1.12 0.167 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 0.895 0.728 – 1.1 0.293 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.04 1 – 1.09 0.0279 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 1.05 0.954 – 1.15 0.32 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 0.992 0.83 – 1.19 0.927 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.02 0.947 – 1.09 0.658 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.996 0.892 – 1.11 0.947 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.05 0.916 – 1.2 0.488 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.04 0.79 – 1.38 0.76 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.02 1 – 1.04 0.0313 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 1.02 1 – 1.04 0.0317 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 0.89 0.708 – 1.12 0.322 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.18 0.93 – 1.5 0.173 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.05 0.917 – 1.2 0.488 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1.06 0.914 – 1.22 0.451 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.987 0.828 – 1.18 0.88 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 0.957 0.84 – 1.09 0.515 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 1.03 1.01 – 1.06 0.00716 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.03 1.01 – 1.06 0.00658 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.09 0.991 – 1.2 0.0778 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 1.1 1.03 – 1.17 0.00297 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 1.11 1.04 – 1.18 0.00147 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 1.12 1.04 – 1.2 0.00326 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.969 0.826 – 1.14 0.7 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 1.12 0.961 – 1.29 0.152 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 0.923 0.706 – 1.21 0.56 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 0.971 0.817 – 1.15 0.733 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.04 0.798 – 1.37 0.755 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.91 0.721 – 1.15 0.428 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 0.942 0.792 – 1.12 0.502 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.931 0.764 – 1.14 0.483 103 1059 all phecode
284 Aplastic anemia Hematopoietic 1.06 0.963 – 1.18 0.225 435 4357 all phecode
285 Other anemias Hematopoietic 1.03 1.01 – 1.05 0.000505 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.94 0.825 – 1.07 0.35 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.07 0.988 – 1.15 0.0972 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.07 0.971 – 1.18 0.169 414 4147 all phecode
286 Coagulation defects Hematopoietic 0.995 0.929 – 1.07 0.895 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 0.993 0.9 – 1.1 0.885 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 0.96 0.78 – 1.18 0.698 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.989 0.874 – 1.12 0.861 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 0.999 0.769 – 1.3 0.996 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.07 0.863 – 1.32 0.549 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.01 0.909 – 1.13 0.831 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.996 0.946 – 1.05 0.876 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.1 0.916 – 1.31 0.316 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 0.9 0.664 – 1.22 0.497 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 0.993 0.941 – 1.05 0.784 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.01 0.916 – 1.12 0.791 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.981 0.777 – 1.24 0.874 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 1.01 0.972 – 1.04 0.74 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 0.989 0.953 – 1.03 0.562 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 0.991 0.955 – 1.03 0.63 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 1.14 0.91 – 1.44 0.25 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.08 1.01 – 1.16 0.0339 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.04 0.919 – 1.17 0.538 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 1.04 0.994 – 1.08 0.0976 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 0.981 0.894 – 1.08 0.685 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.03 0.915 – 1.17 0.588 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.18 0.96 – 1.46 0.114 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.08 1.03 – 1.13 0.00133 1929 19281 all phecode
290.1 Dementias Mental Disorders 1.1 1.03 – 1.18 0.00304 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 1.05 0.947 – 1.16 0.368 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 1.24 1.07 – 1.43 0.00336 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.05 0.965 – 1.13 0.277 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.05 0.821 – 1.34 0.696 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.06 0.99 – 1.14 0.0907 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.889 0.739 – 1.07 0.213 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.03 0.907 – 1.16 0.679 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 1.12 1.02 – 1.24 0.0191 436 4376 all phecode
292 Neurological disorders Mental Disorders 1.02 0.992 – 1.05 0.151 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.06 1 – 1.12 0.0407 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 1.02 0.879 – 1.19 0.774 190 1907 all phecode
292.3 Memory loss Mental Disorders 1.04 0.956 – 1.12 0.394 696 6978 all phecode
292.4 Altered mental status Mental Disorders 0.991 0.947 – 1.04 0.7 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 1.11 0.994 – 1.25 0.0633 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 1.04 0.993 – 1.09 0.0959 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.08 1.01 – 1.16 0.0223 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.01 0.943 – 1.09 0.728 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 1.02 0.94 – 1.12 0.585 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 0.976 0.834 – 1.14 0.76 178 1780 all phecode
295.3 Psychosis Mental Disorders 0.94 0.798 – 1.11 0.459 169 1710 all phecode
296 Mood disorders Mental Disorders 1.02 0.998 – 1.04 0.0828 12372 123822 all phecode
296.1 Bipolar Mental Disorders 1.05 0.981 – 1.11 0.169 1059 10599 all phecode
296.2 Depression Mental Disorders 1.01 0.994 – 1.03 0.174 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 0.975 0.874 – 1.09 0.655 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.98 0.875 – 1.1 0.726 311 3070 all phecode
300 Anxiety disorders Mental Disorders 1.03 1.01 – 1.06 0.0167 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 1.03 1 – 1.06 0.0247 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1.09 0.917 – 1.29 0.327 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.03 0.953 – 1.12 0.445 707 7065 all phecode
300.13 Phobia Mental Disorders 1 0.911 – 1.1 0.987 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.16 0.982 – 1.38 0.08 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 1.04 0.784 – 1.38 0.78 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 1.11 0.921 – 1.33 0.279 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.931 0.768 – 1.13 0.462 113 1129 all phecode
301 Personality disorders Mental Disorders 1.12 0.999 – 1.25 0.0526 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.21 1.01 – 1.45 0.0353 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.996 0.88 – 1.13 0.945 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.11 1.01 – 1.22 0.0306 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 1.14 1.02 – 1.27 0.0163 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 1.12 0.936 – 1.33 0.222 123 1229 all phecode
304 Adjustment reaction Mental Disorders 1 0.89 – 1.13 0.941 293 2936 all phecode
305.2 Eating disorder Mental Disorders 1.11 0.897 – 1.38 0.329 90 900 all phecode
306 Other mental disorder Mental Disorders 1.02 1.01 – 1.04 0.00018 28056 230087 all phecode
306.9 Tension headache Mental Disorders 1.06 0.942 – 1.19 0.344 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 0.967 0.764 – 1.22 0.78 76 770 all phecode
313.3 Autism Mental Disorders 1.11 0.839 – 1.47 0.466 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 0.969 0.868 – 1.08 0.575 351 3517 all phecode
315.1 Learning disorder Mental Disorders 1.15 0.975 – 1.35 0.0973 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 0.961 0.771 – 1.2 0.727 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 1.05 1.02 – 1.08 0.000514 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.975 0.745 – 1.28 0.851 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 1.04 1.03 – 1.06 3.9e-06 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 1.04 1.02 – 1.06 0.00055 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.06 0.984 – 1.13 0.129 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 1.02 1.01 – 1.04 0.00795 19359 185465 all phecode
320 Meningitis Neurological 0.939 0.85 – 1.04 0.218 444 4447 all phecode
323 Encephalitis Neurological 0.954 0.85 – 1.07 0.425 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 0.799 0.621 – 1.03 0.0802 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 0.985 0.872 – 1.11 0.814 292 2916 all phecode
327 Sleep disorders Neurological 1.03 0.973 – 1.1 0.277 1164 11659 all phecode
327.3 Sleep apnea Neurological 1.03 0.996 – 1.06 0.085 4428 44318 all phecode
327.4 Insomnia Neurological 1.01 0.859 – 1.19 0.901 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 0.996 0.833 – 1.19 0.967 136 1390 all phecode
331 Other cerebral degenerations Neurological 1.01 0.946 – 1.07 0.825 1142 11416 all phecode
331.1 Hydrocephalus Neurological 0.944 0.858 – 1.04 0.235 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 1.06 0.957 – 1.17 0.273 430 4298 all phecode
332 Parkinson's disease Neurological 1.05 0.991 – 1.12 0.0918 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.05 0.979 – 1.12 0.178 894 8954 all phecode
333.1 Essential tremor Neurological 1.01 0.878 – 1.17 0.867 216 2157 all phecode
333.2 Myoclonus Neurological 0.952 0.775 – 1.17 0.64 96 958 all phecode
333.4 Torsion dystonia Neurological 1.11 0.975 – 1.26 0.118 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 0.992 0.944 – 1.04 0.736 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 0.948 0.788 – 1.14 0.571 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 1.02 0.892 – 1.16 0.806 245 2446 all phecode
335 Multiple sclerosis Neurological 0.999 0.944 – 1.06 0.966 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 0.974 0.858 – 1.11 0.684 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.02 0.796 – 1.3 0.897 72 719 all phecode
338 Pain Neurological 1.01 0.934 – 1.08 0.865 768 7692 all phecode
338.1 Acute pain Neurological 0.946 0.851 – 1.05 0.298 394 3937 all phecode
338.2 Chronic pain Neurological 1.04 0.94 – 1.16 0.434 380 3817 all phecode
339 Other headache syndromes Neurological 1.02 0.997 – 1.05 0.081 7819 78241 all phecode
340 Migraine Neurological 1 0.966 – 1.04 0.844 2860 28602 all phecode
340.1 Migrain with aura Neurological 0.954 0.824 – 1.1 0.523 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.993 0.874 – 1.13 0.911 252 2535 all phecode
342 Hemiplegia Neurological 1.02 0.968 – 1.08 0.441 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 1.06 0.894 – 1.25 0.507 145 1450 all phecode
344 Other paralytic syndromes Neurological 1 0.925 – 1.09 0.942 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.02 0.987 – 1.05 0.272 5023 50270 all phecode
345.1 Epilepsy Neurological 1.02 0.95 – 1.09 0.609 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 1.05 0.951 – 1.16 0.343 439 4385 all phecode
345.12 Partial epilepsy Neurological 0.996 0.881 – 1.13 0.949 277 2776 all phecode
345.3 Convulsions Neurological 1.05 1 – 1.09 0.0484 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.893 0.748 – 1.07 0.209 144 1438 all phecode
348 Other conditions of brain Neurological 1.04 0.967 – 1.12 0.287 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.02 0.9 – 1.16 0.753 268 2678 all phecode
348.4 Cerebral cysts Neurological 0.979 0.823 – 1.17 0.815 133 1350 all phecode
348.7 Coma Neurological 1.06 0.955 – 1.19 0.259 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.07 0.944 – 1.22 0.281 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 1.09 0.986 – 1.21 0.0904 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.978 0.875 – 1.09 0.702 342 3414 all phecode
350 Abnormal movement Neurological 1.04 1 – 1.08 0.0521 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 1.01 0.943 – 1.08 0.752 887 8852 all phecode
350.2 Abnormality of gait Neurological 1.07 1.02 – 1.13 0.00742 1596 15969 all phecode
350.3 Lack of coordination Neurological 1.04 0.934 – 1.15 0.487 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.02 0.767 – 1.35 0.904 54 540 all phecode
351 Other peripheral nerve disorders Neurological 1.01 0.995 – 1.03 0.14 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 1 0.948 – 1.06 0.911 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.998 0.905 – 1.1 0.967 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.02 0.955 – 1.1 0.499 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 1 0.94 – 1.06 0.995 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 0.929 0.765 – 1.13 0.454 114 1138 all phecode
353.2 Nerve root lesions Neurological 1.02 0.783 – 1.34 0.863 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.997 0.847 – 1.17 0.972 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 0.957 0.904 – 1.01 0.129 1361 13648 all phecode
358 Myoneural disorders Neurological 1.14 0.992 – 1.31 0.0656 211 2109 all phecode
358.1 Myasthenia gravis Neurological 1.12 0.966 – 1.3 0.135 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 1.06 0.961 – 1.16 0.253 465 4646 all phecode
359.1 Muscular dystrophies Neurological 0.962 0.8 – 1.16 0.684 122 1219 all phecode
359.2 Myopathy Neurological 1.09 0.975 – 1.21 0.132 360 3597 all phecode
360 Disorders of the globe Sense Organs 1.12 0.999 – 1.25 0.0512 337 3367 all phecode
360.2 Progressive myopia Sense Organs 1.13 0.993 – 1.28 0.0633 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 0.985 0.949 – 1.02 0.433 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.02 0.963 – 1.08 0.521 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.791 0.603 – 1.04 0.0915 68 680 all phecode
362 Other retinal disorders Sense Organs 1 0.971 – 1.04 0.807 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.01 0.97 – 1.06 0.518 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.02 0.971 – 1.06 0.497 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.02 0.858 – 1.2 0.858 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 1.04 0.838 – 1.28 0.747 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.99 0.922 – 1.06 0.789 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 1 0.851 – 1.18 0.995 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 1 0.797 – 1.27 0.97 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1 0.83 – 1.22 0.962 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.09 0.93 – 1.28 0.279 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 0.973 0.757 – 1.25 0.832 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1 0.925 – 1.09 0.923 647 6485 all phecode
364.1 Corneal opacity Sense Organs 1.14 0.915 – 1.41 0.244 90 910 all phecode
364.2 Corneal edema Sense Organs 0.913 0.725 – 1.15 0.436 79 800 all phecode
364.4 Corneal degenerations Sense Organs 0.961 0.827 – 1.12 0.599 201 2017 all phecode
364.41 Keratoconus Sense Organs 0.954 0.761 – 1.2 0.68 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 1.13 0.982 – 1.31 0.0867 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 1.21 0.985 – 1.49 0.0699 100 1000 all phecode
365 Glaucoma Sense Organs 1.03 1 – 1.07 0.0448 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 1.06 0.994 – 1.13 0.0734 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.06 0.997 – 1.13 0.0598 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.02 0.945 – 1.11 0.581 698 6996 all phecode
366 Cataract Sense Organs 1.03 1.01 – 1.04 0.000889 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 1.17 0.918 – 1.49 0.205 69 700 all phecode
366.2 Senile cataract Sense Organs 1.04 1.01 – 1.06 0.00153 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 0.882 0.719 – 1.08 0.232 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.03 0.992 – 1.08 0.117 2408 24092 all phecode
367.1 Myopia Sense Organs 1.05 0.987 – 1.11 0.127 1251 12519 all phecode
367.2 Astigmatism Sense Organs 1.15 0.997 – 1.33 0.0556 190 1899 all phecode
367.8 Hypermetropia Sense Organs 1.05 0.923 – 1.19 0.469 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 1.02 0.941 – 1.1 0.675 719 7198 all phecode
368 Visual disturbances Sense Organs 1.02 0.978 – 1.06 0.401 2962 29648 all phecode
368.1 Amblyopia Sense Organs 1.09 0.996 – 1.19 0.0625 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.984 0.91 – 1.06 0.693 727 7288 all phecode
368.3 Anisometropia Sense Organs 1.13 0.954 – 1.33 0.16 154 1548 all phecode
368.4 Visual field defects Sense Organs 1.12 0.997 – 1.25 0.0563 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 0.997 0.917 – 1.08 0.949 612 6115 all phecode
369 Infection of the eye Sense Organs 1.1 1.01 – 1.2 0.0299 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 1.19 0.988 – 1.44 0.0666 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 1.16 1.01 – 1.33 0.0366 213 2128 all phecode
370 Keratitis Sense Organs 0.99 0.876 – 1.12 0.872 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 0.995 0.836 – 1.18 0.955 141 1408 all phecode
371 Inflammation of the eye Sense Organs 0.983 0.946 – 1.02 0.364 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.961 0.874 – 1.06 0.41 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 1 0.961 – 1.05 0.872 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 0.982 0.909 – 1.06 0.641 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 1.06 1.03 – 1.09 9.86e-05 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 1.09 1.02 – 1.16 0.0073 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 1.04 0.995 – 1.1 0.0792 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 1.05 1 – 1.09 0.0484 2204 22031 all phecode
375.2 Epiphora Sense Organs 1.07 0.998 – 1.14 0.0563 898 8969 all phecode
376 Disorders of the orbit Sense Organs 1.09 0.866 – 1.36 0.476 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.04 0.929 – 1.16 0.512 361 3618 all phecode
377.1 Optic atrophy Sense Organs 0.85 0.639 – 1.13 0.267 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.956 0.792 – 1.15 0.637 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.06 1 – 1.12 0.0432 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.06 0.986 – 1.13 0.119 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.947 0.821 – 1.09 0.461 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 1.11 0.979 – 1.26 0.102 275 2755 all phecode
379 Other disorders of eye Sense Organs 1.03 0.997 – 1.07 0.0764 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 1 0.947 – 1.06 0.913 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.08 1.03 – 1.13 0.00265 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 0.859 0.662 – 1.11 0.252 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.965 0.869 – 1.07 0.501 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.06 0.909 – 1.24 0.443 169 1690 all phecode
380 Disorders of external ear Sense Organs 0.992 0.913 – 1.08 0.845 642 6413 all phecode
380.1 Otitis externa Sense Organs 1.06 0.97 – 1.16 0.195 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 0.998 0.895 – 1.11 0.969 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.02 0.975 – 1.07 0.396 2150 21493 all phecode
381.1 Otitis media Sense Organs 1.03 0.979 – 1.08 0.271 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.04 0.965 – 1.11 0.333 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 0.874 0.748 – 1.02 0.0919 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 0.986 0.837 – 1.16 0.864 171 1709 all phecode
381.9 Otorrhea Sense Organs 1.02 0.904 – 1.16 0.726 281 2807 all phecode
382 Otalgia Sense Organs 0.921 0.817 – 1.04 0.176 308 3084 all phecode
383 Otosclerosis Sense Organs 1.07 0.951 – 1.2 0.269 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 0.995 0.94 – 1.05 0.874 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.01 0.946 – 1.07 0.824 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.07 0.991 – 1.15 0.0835 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 1.11 1.03 – 1.21 0.0106 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.02 0.893 – 1.16 0.77 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.04 0.99 – 1.09 0.12 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 1.11 1.02 – 1.2 0.0171 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 0.976 0.877 – 1.09 0.653 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 1.01 0.94 – 1.09 0.736 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.07 1.03 – 1.1 4.31e-05 4582 45806 all phecode
388 Other disorders of ear Sense Organs 1.13 0.983 – 1.31 0.0842 202 2017 all phecode
389 Hearing loss Sense Organs 1.04 1.01 – 1.08 0.0126 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.978 0.887 – 1.08 0.656 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 1.1 0.999 – 1.21 0.0518 450 4497 all phecode
389.4 Tinnitus Sense Organs 0.983 0.897 – 1.08 0.71 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.01 0.982 – 1.04 0.438 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 0.999 0.961 – 1.04 0.94 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 1.03 0.972 – 1.09 0.315 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.03 0.965 – 1.1 0.376 1058 10566 all phecode
395 Heart valve disorders Circulatory System 0.998 0.967 – 1.03 0.916 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.991 0.954 – 1.03 0.666 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.946 0.835 – 1.07 0.384 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.27 1.05 – 1.53 0.0131 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.942 0.76 – 1.17 0.586 97 970 all phecode
395.6 Heart valve replaced Circulatory System 1.02 0.967 – 1.08 0.457 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 0.931 0.871 – 0.995 0.034 1048 10468 all phecode
401 Hypertension Circulatory System 1.02 1.01 – 1.03 0.000155 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 1.02 1.01 – 1.03 0.000167 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.05 1 – 1.1 0.0458 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 0.989 0.886 – 1.1 0.839 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.06 1.01 – 1.12 0.0255 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 1.02 0.858 – 1.22 0.805 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.01 0.952 – 1.06 0.855 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 1.01 1 – 1.03 0.0292 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.04 1.01 – 1.07 0.00528 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 1.01 0.993 – 1.03 0.201 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 1.03 1.01 – 1.05 0.000687 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.01 1 – 1.03 0.0539 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.946 0.872 – 1.03 0.178 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.02 1 – 1.04 0.0152 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.993 0.935 – 1.06 0.825 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 0.987 0.939 – 1.04 0.59 1823 18228 all phecode
414.2 ASCVD Circulatory System 0.842 0.645 – 1.1 0.209 72 719 all phecode
415 Pulmonary heart disease Circulatory System 1.02 0.987 – 1.05 0.26 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.08 0.856 – 1.35 0.531 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.06 0.972 – 1.15 0.192 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.07 0.975 – 1.18 0.146 448 4475 all phecode
416 Cardiomegaly Circulatory System 1.04 0.999 – 1.08 0.0559 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 1.02 1.01 – 1.03 0.00273 28599 270106 all phecode
418.1 Precordial pain Circulatory System 1.05 1.01 – 1.08 0.00971 3551 35541 all phecode
420 Carditis Circulatory System 1.03 0.983 – 1.08 0.219 2106 21053 all phecode
420.1 Myocarditis Circulatory System 0.902 0.748 – 1.09 0.278 127 1267 all phecode
420.2 Pericarditis Circulatory System 1.03 0.977 – 1.09 0.246 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 1.11 0.968 – 1.27 0.133 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 1.11 0.923 – 1.34 0.264 113 1129 all phecode
420.3 Endocarditis Circulatory System 1.03 0.958 – 1.12 0.387 719 7194 all phecode
425 Cardiomyopathy Circulatory System 0.986 0.93 – 1.05 0.645 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.986 0.929 – 1.05 0.65 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.986 0.826 – 1.18 0.875 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.884 0.749 – 1.04 0.143 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 1.01 0.774 – 1.31 0.957 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 1.04 1.01 – 1.06 0.00609 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.01 0.964 – 1.06 0.698 2114 21162 all phecode
426.21 First degree AV block Circulatory System 1 0.938 – 1.07 0.95 986 9867 all phecode
426.23 Second degree AV block Circulatory System 1.05 0.948 – 1.15 0.378 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 0.99 0.908 – 1.08 0.82 587 5868 all phecode
426.25 Other heart block Circulatory System 0.903 0.749 – 1.09 0.288 131 1318 all phecode
426.3 Bundle branch block Circulatory System 1.04 1 – 1.08 0.0348 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 1.07 1.01 – 1.13 0.0123 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 1.02 0.972 – 1.07 0.395 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.976 0.852 – 1.12 0.73 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.31 1.02 – 1.67 0.0336 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.05 1.01 – 1.09 0.0271 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.04 0.996 – 1.09 0.0785 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 1.01 0.998 – 1.03 0.102 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 0.987 0.951 – 1.02 0.489 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.981 0.94 – 1.02 0.39 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.02 0.957 – 1.1 0.498 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.01 0.995 – 1.03 0.149 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1 0.967 – 1.04 0.857 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.04 0.98 – 1.1 0.198 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.01 0.908 – 1.13 0.805 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 1.03 0.96 – 1.1 0.457 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.983 0.918 – 1.05 0.614 952 9541 all phecode
427.6 Premature beats Circulatory System 1.05 0.96 – 1.15 0.285 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 0.979 0.803 – 1.19 0.834 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 1.02 0.977 – 1.07 0.343 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.04 0.936 – 1.15 0.486 402 4029 all phecode
427.9 Palpitations Circulatory System 1.02 0.991 – 1.06 0.154 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.02 0.99 – 1.05 0.22 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.02 0.979 – 1.07 0.298 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 1.01 0.983 – 1.05 0.393 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.04 0.962 – 1.12 0.337 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 0.954 0.738 – 1.23 0.719 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.04 0.948 – 1.14 0.42 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.03 0.893 – 1.19 0.688 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 1 0.953 – 1.05 0.971 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.01 0.943 – 1.09 0.706 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1.02 0.941 – 1.09 0.697 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 0.862 0.753 – 0.985 0.0297 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 1.02 0.998 – 1.04 0.0689 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.06 1 – 1.13 0.0406 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.12 0.98 – 1.28 0.0961 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.03 1 – 1.07 0.0461 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.03 0.977 – 1.08 0.291 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 1.01 0.969 – 1.05 0.725 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.02 0.974 – 1.07 0.41 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 1.02 0.918 – 1.13 0.717 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.03 0.973 – 1.09 0.3 1279 12783 all phecode
440 Atherosclerosis Circulatory System 0.993 0.938 – 1.05 0.797 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.992 0.819 – 1.2 0.934 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.975 0.906 – 1.05 0.508 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 0.962 0.848 – 1.09 0.543 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.1 1.01 – 1.19 0.0283 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.974 0.861 – 1.1 0.676 283 2827 all phecode
442 Other aneurysm Circulatory System 1.02 0.968 – 1.07 0.529 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 1.02 0.962 – 1.07 0.571 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.02 0.954 – 1.09 0.553 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 0.989 0.809 – 1.21 0.914 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.11 0.953 – 1.3 0.177 169 1696 all phecode
442.4 Arterial dissection Circulatory System 1.21 0.919 – 1.58 0.176 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 0.956 0.826 – 1.11 0.541 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 1.03 1 – 1.07 0.0446 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 1.04 0.977 – 1.1 0.226 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.958 0.862 – 1.07 0.43 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.04 1.01 – 1.08 0.0228 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.05 1.01 – 1.09 0.0263 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.06 0.988 – 1.13 0.104 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.06 0.973 – 1.16 0.179 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.986 0.916 – 1.06 0.702 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 0.929 0.795 – 1.08 0.35 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 1.02 0.919 – 1.14 0.691 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 0.99 0.866 – 1.13 0.88 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.01 0.955 – 1.07 0.694 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 1.04 0.971 – 1.12 0.256 868 8712 all phecode
448 Disease of capillaries Circulatory System 1.12 0.944 – 1.33 0.191 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.983 0.908 – 1.07 0.682 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.02 0.989 – 1.06 0.199 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.02 0.986 – 1.06 0.241 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.976 0.893 – 1.07 0.59 564 5645 all phecode
454 Varicose veins Circulatory System 0.997 0.978 – 1.02 0.798 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 0.995 0.976 – 1.01 0.598 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.988 0.909 – 1.07 0.771 624 6325 all phecode
455 Hemorrhoids Circulatory System 1.02 1.01 – 1.03 0.0053 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.968 0.831 – 1.13 0.678 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.924 0.753 – 1.13 0.445 97 967 all phecode
458 Hypotension Circulatory System 1.02 0.99 – 1.05 0.204 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 1.01 0.957 – 1.07 0.658 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.17 1.03 – 1.34 0.0181 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 1.01 0.979 – 1.05 0.437 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 1.03 1.01 – 1.04 0.00104 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 1.01 0.851 – 1.2 0.909 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 1.03 1.01 – 1.05 0.000618 16103 159422 all phecode
464 Acute sinusitis Respiratory 0.998 0.86 – 1.16 0.979 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.02 0.974 – 1.06 0.438 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 0.965 0.898 – 1.04 0.336 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.1 0.937 – 1.29 0.244 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.02 0.989 – 1.05 0.201 4654 46553 all phecode
471 Nasal polyps Respiratory 1.08 1.04 – 1.12 2.62e-05 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.13 1.06 – 1.2 0.000307 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1.05 1.01 – 1.09 0.0186 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 0.949 0.775 – 1.16 0.612 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.08 0.957 – 1.23 0.205 264 2647 all phecode
473.4 Voice disturbance Respiratory 1.11 1.05 – 1.19 0.000607 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 0.98 0.933 – 1.03 0.428 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 0.988 0.904 – 1.08 0.79 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.979 0.92 – 1.04 0.502 1122 11199 all phecode
475 Chronic sinusitis Respiratory 1.03 0.991 – 1.07 0.131 2589 25882 all phecode
476 Allergic rhinitis Respiratory 1 0.941 – 1.07 0.915 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 0.978 0.937 – 1.02 0.294 2447 24452 all phecode
478 Throat pain Respiratory 1.05 0.939 – 1.17 0.408 377 3789 all phecode
479 Other upper respiratory disease Respiratory 1.04 1.01 – 1.08 0.0107 4074 40737 all phecode
480 Pneumonia Respiratory 1.02 1 – 1.04 0.0256 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 1.03 1 – 1.06 0.028 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.03 1 – 1.06 0.0222 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.07 0.858 – 1.32 0.567 93 929 all phecode
480.2 Viral pneumonia Respiratory 1.13 0.889 – 1.45 0.309 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.938 0.764 – 1.15 0.545 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.953 0.885 – 1.03 0.207 794 7951 all phecode
481 Influenza Respiratory 0.996 0.889 – 1.12 0.944 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.1 0.947 – 1.27 0.221 193 1930 all phecode
495 Asthma Respiratory 1.02 1 – 1.03 0.0129 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 0.951 0.833 – 1.08 0.45 250 2510 all phecode
496 Chronic airway obstruction Respiratory 1.04 1.02 – 1.06 8.79e-05 10424 101546 all phecode
496.1 Emphysema Respiratory 1.04 0.99 – 1.09 0.118 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 1.02 0.986 – 1.06 0.228 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.02 0.983 – 1.06 0.257 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 1.04 0.996 – 1.1 0.0733 1885 18859 all phecode
497 Bronchitis Respiratory 0.973 0.895 – 1.06 0.519 626 6267 all phecode
500 Lung disease due to external agents Respiratory 1.08 0.978 – 1.2 0.128 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.12 0.893 – 1.4 0.326 79 784 all phecode
500.2 Pneumoconiosis Respiratory 1.09 0.958 – 1.24 0.191 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.1 1.02 – 1.19 0.0182 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.01 0.947 – 1.09 0.689 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.03 0.945 – 1.13 0.458 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.02 0.913 – 1.15 0.694 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 0.87 0.66 – 1.15 0.324 61 610 all phecode
506 Empyema and pneumothorax Respiratory 1.02 0.958 – 1.08 0.549 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 1.02 0.998 – 1.05 0.0681 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.02 0.97 – 1.06 0.51 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.03 0.991 – 1.07 0.127 2599 26031 all phecode
509.1 Respiratory failure Respiratory 1.04 0.991 – 1.08 0.119 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 1.03 0.978 – 1.08 0.278 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 0.991 0.838 – 1.17 0.914 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.1 0.992 – 1.23 0.0694 386 3863 all phecode
510 Other diseases of lung Respiratory 1.08 0.998 – 1.16 0.0571 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 1.04 1.02 – 1.06 0.00079 9031 90349 all phecode
512.1 Wheezing Respiratory 1.03 0.899 – 1.18 0.679 220 2196 all phecode
512.2 Painful respiration Respiratory 0.985 0.856 – 1.13 0.835 207 2075 all phecode
512.7 Shortness of breath Respiratory 1.04 1.01 – 1.07 0.0037 5842 58498 all phecode
512.8 Cough Respiratory 1.04 1 – 1.08 0.03 2866 28642 all phecode
512.9 Other dyspnea Respiratory 1.05 0.98 – 1.12 0.174 914 9124 all phecode
513 Respiratory abnormalities Respiratory 1.04 0.952 – 1.13 0.419 611 6112 all phecode
513.3 Hypoventilation Respiratory 0.922 0.729 – 1.17 0.502 83 830 all phecode
513.4 Hyperventilation Respiratory 0.961 0.846 – 1.09 0.538 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 1.01 0.852 – 1.19 0.918 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 1.03 0.991 – 1.08 0.127 2465 24673 all phecode
516 Abnormal sputum Respiratory 0.995 0.952 – 1.04 0.828 2132 21335 all phecode
516.1 Hemoptysis Respiratory 1.01 0.966 – 1.06 0.645 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.03 1.01 – 1.06 0.00208 9366 93681 all phecode
519.2 Respiratory complications Respiratory 1.01 0.9 – 1.13 0.906 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.04 1.01 – 1.06 0.00153 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.966 0.859 – 1.09 0.559 303 3049 all phecode
520 Disorders of tooth development Digestive 1.01 0.963 – 1.06 0.711 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.85 0.629 – 1.15 0.289 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 1.03 0.99 – 1.08 0.129 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 0.996 0.959 – 1.03 0.844 3016 30245 all phecode
521.1 Dental caries Digestive 1 0.963 – 1.04 0.974 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 0.942 0.896 – 0.99 0.0195 1774 17750 all phecode
522.5 Periapical abscess Digestive 0.933 0.877 – 0.992 0.0271 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 0.986 0.937 – 1.04 0.578 1681 16812 all phecode
523.1 Gingivitis Digestive 1.04 0.858 – 1.26 0.684 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.01 0.947 – 1.07 0.85 1165 11650 all phecode
523.31 Acute periodontitis Digestive 1.06 0.978 – 1.15 0.155 666 6667 all phecode
523.32 Chronic periodontitis Digestive 0.939 0.861 – 1.02 0.156 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.04 0.932 – 1.17 0.452 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.03 0.917 – 1.17 0.581 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.999 0.96 – 1.04 0.98 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.789 0.609 – 1.02 0.0723 72 720 all phecode
526 Diseases of the jaws Digestive 0.967 0.903 – 1.04 0.345 928 9279 all phecode
526.1 Cysts of the jaws Digestive 0.982 0.876 – 1.1 0.758 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.824 0.637 – 1.06 0.139 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.06 0.931 – 1.2 0.385 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.04 0.917 – 1.19 0.509 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.879 0.714 – 1.08 0.223 110 1098 all phecode
526.9 Jaw disease NOS Digestive 0.931 0.811 – 1.07 0.313 233 2329 all phecode
527 Diseases of the salivary glands Digestive 0.975 0.901 – 1.06 0.533 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 0.874 0.693 – 1.1 0.255 84 838 all phecode
527.2 Sialoadenitis Digestive 0.968 0.869 – 1.08 0.559 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 1.14 0.878 – 1.47 0.33 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.01 0.843 – 1.22 0.887 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.03 0.993 – 1.06 0.127 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 1.17 1.07 – 1.28 0.000836 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.18 1.07 – 1.31 0.00107 389 3884 all phecode
528.12 Oral aphthae Digestive 1.03 0.82 – 1.29 0.804 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.927 0.79 – 1.09 0.352 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 0.91 0.749 – 1.1 0.34 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 0.884 0.708 – 1.1 0.277 94 940 all phecode
528.5 Diseases of lips Digestive 1.07 0.988 – 1.16 0.0984 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.01 0.895 – 1.13 0.914 308 3079 all phecode
528.7 Sialolithiasis Digestive 1.07 0.956 – 1.2 0.233 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 0.986 0.929 – 1.05 0.643 1232 12312 all phecode
529.1 Glossitis Digestive 0.947 0.84 – 1.07 0.375 299 2986 all phecode
530 Diseases of esophagus Digestive 1.02 1.01 – 1.03 0.000241 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.02 1.01 – 1.04 0.000172 31253 272429 all phecode
530.11 GERD Digestive 1.02 1 – 1.03 0.0243 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 1.05 1.02 – 1.08 0.00185 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 1.01 0.991 – 1.03 0.282 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.05 1 – 1.11 0.0398 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 0.995 0.948 – 1.04 0.827 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 1 0.921 – 1.09 0.976 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.11 0.944 – 1.31 0.207 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.02 0.913 – 1.14 0.705 341 3416 all phecode
530.9 Heartburn Digestive 1.05 1 – 1.1 0.0411 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.02 0.993 – 1.04 0.167 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.02 0.941 – 1.11 0.615 637 6374 all phecode
531.2 Gastric ulcer Digestive 1.01 0.982 – 1.05 0.398 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 1.01 0.972 – 1.05 0.617 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.16 1.05 – 1.28 0.00227 427 4268 all phecode
532 Dysphagia Digestive 1.03 1.01 – 1.06 0.0111 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 1.04 1.02 – 1.05 3.72e-08 28078 261548 all phecode
535.1 Acute gastritis Digestive 0.999 0.941 – 1.06 0.961 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 1.05 0.946 – 1.17 0.348 370 3687 all phecode
535.6 Duodenitis Digestive 1.02 0.994 – 1.04 0.138 7592 75928 all phecode
535.8 Other specified gastritis Digestive 1.03 1.01 – 1.06 0.00822 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.07 0.897 – 1.27 0.457 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.08 0.962 – 1.22 0.185 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 1.05 1.01 – 1.08 0.0127 3391 33907 all phecode
540 Appendiceal conditions Digestive 0.977 0.941 – 1.01 0.222 3088 30890 all phecode
540.1 Appendicitis Digestive 0.972 0.935 – 1.01 0.159 2895 28963 all phecode
540.11 Acute appendicitis Digestive 0.976 0.937 – 1.02 0.248 2601 26019 all phecode
550 Abdominal hernia Digestive 1.02 1.01 – 1.03 5.75e-05 45429 282640 all phecode
550.1 Inguinal hernia Digestive 1.02 0.999 – 1.03 0.0629 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 1.03 1.02 – 1.05 2.1e-07 26494 238953 all phecode
550.3 Femoral hernia Digestive 0.977 0.901 – 1.06 0.58 651 6504 all phecode
550.4 Umbilical hernia Digestive 1.01 0.975 – 1.04 0.603 3705 37072 all phecode
550.5 Ventral hernia Digestive 1.04 1 – 1.08 0.028 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.01 0.981 – 1.04 0.455 4444 44442 all phecode
555.1 Regional enteritis Digestive 0.986 0.938 – 1.04 0.59 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 1.02 0.982 – 1.06 0.321 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 0.978 0.894 – 1.07 0.629 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 1.07 1.01 – 1.14 0.031 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 1.05 0.967 – 1.14 0.252 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.957 0.848 – 1.08 0.482 299 2987 all phecode
557.1 Celiac disease Digestive 0.995 0.948 – 1.05 0.853 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 1.03 1.02 – 1.05 0.000101 15492 155105 all phecode
559 Ileostomy status Digestive 1.02 0.965 – 1.07 0.55 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.03 0.994 – 1.06 0.107 3936 39337 all phecode
560.1 Paralytic ileus Digestive 1.09 0.996 – 1.19 0.06 523 5231 all phecode
560.2 Impaction of intestine Digestive 0.98 0.863 – 1.11 0.759 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.03 0.957 – 1.1 0.452 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 1.02 0.987 – 1.06 0.22 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 1.01 0.993 – 1.03 0.24 15772 157686 all phecode
561.1 Diarrhea Digestive 1.03 0.939 – 1.13 0.517 466 4653 all phecode
561.2 Flatulence Digestive 1.04 0.987 – 1.09 0.148 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 1.02 1.01 – 1.03 0.00219 26714 211692 all phecode
562.1 Diverticulosis Digestive 1.02 1.01 – 1.03 0.00207 26672 211642 all phecode
563 Constipation Digestive 1 0.984 – 1.02 0.698 10314 103140 all phecode
564 Functional digestive disorders Digestive 1.02 1 – 1.03 0.0299 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.02 0.992 – 1.05 0.162 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 0.974 0.925 – 1.03 0.328 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 1.03 1.01 – 1.04 0.00317 15186 151648 all phecode
565 Anal and rectal conditions Digestive 1.01 0.995 – 1.03 0.17 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 1.01 0.99 – 1.04 0.261 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 0.993 0.927 – 1.06 0.846 929 9293 all phecode
568 Other disorders of peritoneum Digestive 1.03 0.989 – 1.06 0.178 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.02 0.987 – 1.06 0.21 3101 30987 all phecode
569 Other disorders of intestine Digestive 1.01 0.98 – 1.05 0.456 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.04 0.876 – 1.23 0.654 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 0.972 0.884 – 1.07 0.555 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.07 1.03 – 1.11 0.00031 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.04 0.99 – 1.09 0.12 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.854 0.703 – 1.04 0.114 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 1.18 1.04 – 1.34 0.00957 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.1 1.03 – 1.17 0.00621 976 9804 all phecode
571.81 Portal hypertension Digestive 1.13 1.04 – 1.23 0.00593 528 5285 all phecode
572 Ascites (non malignant) Digestive 1.03 0.979 – 1.09 0.247 1544 15454 all phecode
573 Other disorders of liver Digestive 1.03 0.977 – 1.09 0.266 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 1.06 0.859 – 1.3 0.599 96 960 all phecode
573.3 Hepatomegaly Digestive 1.04 0.92 – 1.17 0.552 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 1.05 0.979 – 1.13 0.17 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 1.05 1.01 – 1.09 0.00551 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.2 1.04 – 1.38 0.0104 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.02 1.01 – 1.04 0.0083 15607 156123 all phecode
574.1 Cholelithiasis Digestive 1.02 1 – 1.04 0.017 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.05 0.998 – 1.11 0.0579 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.02 0.987 – 1.04 0.293 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 1.02 0.983 – 1.07 0.264 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.03 0.993 – 1.07 0.105 2748 27523 all phecode
575 Other biliary tract disease Digestive 1.04 1.01 – 1.08 0.0183 3867 38724 all phecode
575.1 Cholangitis Digestive 1.02 0.93 – 1.12 0.668 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 1.02 0.947 – 1.1 0.586 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 1.05 0.953 – 1.15 0.331 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 1.07 1.01 – 1.13 0.0135 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 1.06 0.996 – 1.13 0.0681 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.892 0.796 – 0.999 0.0482 348 3488 all phecode
577 Diseases of pancreas Digestive 1.06 1.01 – 1.1 0.00797 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 1.07 1.02 – 1.12 0.00722 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 1.04 0.951 – 1.14 0.383 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.989 0.887 – 1.1 0.843 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 1.02 1.01 – 1.04 0.000945 20626 206278 all phecode
578.1 Hematemesis Digestive 1.03 0.986 – 1.08 0.167 1958 19564 all phecode
578.2 Blood in stool Digestive 1.04 0.995 – 1.08 0.0874 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.03 1.02 – 1.05 0.000218 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.02 0.987 – 1.04 0.297 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.04 0.99 – 1.1 0.111 1548 15498 all phecode
579.2 Splenomegaly Digestive 1.05 0.948 – 1.16 0.356 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.03 0.977 – 1.08 0.285 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.02 0.971 – 1.08 0.391 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 1.02 0.953 – 1.08 0.627 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.03 0.82 – 1.3 0.775 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.02 0.848 – 1.22 0.87 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.01 0.94 – 1.08 0.806 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.05 0.958 – 1.16 0.284 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.04 0.916 – 1.19 0.517 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.06 0.933 – 1.21 0.363 253 2529 all phecode
585 Renal failure Genitourinary 1.02 0.992 – 1.04 0.178 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 1.01 0.975 – 1.04 0.732 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 1.02 0.969 – 1.08 0.401 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.02 0.983 – 1.07 0.257 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 1.06 0.972 – 1.17 0.178 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.01 0.977 – 1.05 0.496 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.01 0.879 – 1.17 0.845 208 2089 all phecode
586.11 Small kidney Genitourinary 1.01 0.862 – 1.18 0.926 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 0.993 0.936 – 1.05 0.82 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.02 0.811 – 1.29 0.86 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.01 0.944 – 1.08 0.754 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 1.09 0.983 – 1.21 0.102 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.1 0.901 – 1.34 0.352 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 0.972 0.8 – 1.18 0.775 116 1158 all phecode
590 Pyelonephritis Genitourinary 1.02 0.962 – 1.08 0.538 1328 13285 all phecode
591 Urinary tract infection Genitourinary 1.01 0.995 – 1.03 0.161 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 1.04 1 – 1.08 0.0468 2966 29661 all phecode
592.1 Cystitis Genitourinary 1.04 1 – 1.08 0.0432 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 1.05 0.89 – 1.25 0.539 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 1.04 0.973 – 1.12 0.244 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 1.07 0.941 – 1.22 0.303 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.973 0.829 – 1.14 0.738 165 1662 all phecode
593 Hematuria Genitourinary 1.02 1 – 1.03 0.0385 16068 160204 all phecode
594 Urinary calculus Genitourinary 1.02 0.996 – 1.05 0.0913 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 1.03 0.989 – 1.06 0.173 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.05 0.977 – 1.13 0.18 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 1.01 0.969 – 1.05 0.621 2401 24024 all phecode
594.8 Renal colic Genitourinary 1.01 0.963 – 1.06 0.71 2050 20500 all phecode
595 Hydronephrosis Genitourinary 0.988 0.942 – 1.04 0.613 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 1.02 0.998 – 1.04 0.0755 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 1.04 0.988 – 1.09 0.144 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 1.05 1 – 1.11 0.043 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.01 0.973 – 1.04 0.732 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.01 0.972 – 1.04 0.676 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 1.06 0.835 – 1.34 0.64 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.02 0.984 – 1.06 0.286 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.04 0.923 – 1.17 0.534 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.995 – 1.03 0.177 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 0.954 0.811 – 1.12 0.567 166 1670 all phecode
599.2 Retention of urine Genitourinary 1.02 0.994 – 1.05 0.139 6718 67168 all phecode
599.3 Dysuria Genitourinary 1.07 1.01 – 1.13 0.0317 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 1 0.981 – 1.03 0.774 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.01 0.981 – 1.05 0.418 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 0.984 0.806 – 1.2 0.87 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.05 0.811 – 1.35 0.731 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 1.05 0.997 – 1.1 0.0654 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 1.01 0.988 – 1.03 0.442 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.991 0.947 – 1.04 0.71 2081 20818 all phecode
601.1 Prostatitis Genitourinary 1.02 0.963 – 1.07 0.581 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 0.979 0.854 – 1.12 0.76 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 1.05 0.979 – 1.12 0.181 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.21 0.943 – 1.55 0.134 59 588 all phecode
601.4 Balanoposthitis Genitourinary 0.905 0.797 – 1.03 0.123 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.987 0.876 – 1.11 0.834 303 3019 all phecode
602 Other disorders of prostate Genitourinary 0.955 0.902 – 1.01 0.122 1341 13408 all phecode
603 Other disorders of testis Genitourinary 1.02 0.971 – 1.06 0.486 2150 21512 all phecode
603.1 Hydrocele Genitourinary 0.993 0.938 – 1.05 0.803 1339 13402 all phecode
604 Disorders of penis Genitourinary 1 0.967 – 1.04 0.879 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.996 0.957 – 1.04 0.85 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.07 0.947 – 1.21 0.282 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 1.02 0.982 – 1.06 0.288 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1 0.867 – 1.16 0.953 214 2138 all phecode
609.1 Infertility, male Genitourinary 0.946 0.739 – 1.21 0.662 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 1.04 0.875 – 1.23 0.686 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 1.02 0.974 – 1.06 0.483 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 1.11 1.04 – 1.18 0.00248 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.02 0.907 – 1.15 0.735 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 0.977 0.861 – 1.11 0.713 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 1 0.947 – 1.06 0.963 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.04 0.961 – 1.12 0.335 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.995 0.944 – 1.05 0.845 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 1.01 0.768 – 1.32 0.957 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 0.991 0.939 – 1.05 0.739 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.953 0.888 – 1.02 0.175 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.97 0.903 – 1.04 0.399 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 0.802 0.625 – 1.03 0.0828 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 1.05 0.999 – 1.11 0.054 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.09 1.01 – 1.17 0.0326 720 7210 all phecode
613.5 Mastodynia Genitourinary 0.979 0.779 – 1.23 0.857 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 1.1 1.02 – 1.19 0.0124 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 1.07 0.957 – 1.2 0.23 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 1.08 0.943 – 1.24 0.266 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.03 1.01 – 1.06 0.0152 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.05 1.01 – 1.09 0.0233 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1 0.931 – 1.08 0.977 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.987 0.762 – 1.28 0.919 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.03 0.931 – 1.14 0.575 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.05 0.937 – 1.17 0.419 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.992 0.871 – 1.13 0.905 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.04 0.998 – 1.08 0.0607 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.06 0.998 – 1.12 0.0607 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1 0.907 – 1.11 0.98 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.01 0.936 – 1.09 0.818 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.06 0.939 – 1.2 0.336 274 2737 all phecode
615 Endometriosis Genitourinary 1.03 0.997 – 1.06 0.0741 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.07 0.945 – 1.2 0.303 304 3037 all phecode
618 Genital prolapse Genitourinary 1.01 0.988 – 1.03 0.435 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1.02 0.995 – 1.04 0.12 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.987 0.959 – 1.02 0.364 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.06 0.968 – 1.16 0.205 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.05 0.973 – 1.14 0.195 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 1.02 1 – 1.05 0.0356 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.963 0.891 – 1.04 0.341 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1.03 0.997 – 1.07 0.0764 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.03 0.994 – 1.07 0.0985 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.993 0.945 – 1.04 0.775 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.06 1 – 1.12 0.0349 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 0.908 0.714 – 1.16 0.433 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 1 0.944 – 1.07 0.895 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 1.02 0.999 – 1.04 0.063 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 1.02 0.999 – 1.05 0.0647 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 1.05 1.01 – 1.08 0.0128 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.03 0.969 – 1.09 0.355 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 1.06 0.983 – 1.13 0.137 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 1.02 0.891 – 1.17 0.774 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 1.08 0.977 – 1.19 0.138 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 0.997 0.97 – 1.02 0.829 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.03 0.996 – 1.08 0.0834 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 1.05 0.986 – 1.11 0.135 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.01 0.997 – 1.03 0.0981 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.01 0.988 – 1.02 0.526 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 1.17 0.962 – 1.42 0.115 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.02 0.999 – 1.04 0.0664 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 1.02 0.97 – 1.06 0.492 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.995 0.962 – 1.03 0.791 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 1.01 0.964 – 1.06 0.622 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 1 0.85 – 1.18 0.988 159 1587 all phecode
626.8 Infertility, female Genitourinary 1.11 1.05 – 1.18 0.000116 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.02 0.998 – 1.04 0.0838 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 1.02 1 – 1.04 0.0497 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 0.889 0.761 – 1.04 0.138 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.999 0.938 – 1.06 0.962 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.941 0.837 – 1.06 0.311 310 3097 all phecode
628 Ovarian cyst Genitourinary 1.05 1.02 – 1.08 0.00303 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.02 0.992 – 1.05 0.148 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.08 1.01 – 1.14 0.0181 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.06 0.948 – 1.19 0.301 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.01 0.96 – 1.05 0.8 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.972 0.905 – 1.04 0.433 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.04 0.98 – 1.1 0.201 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.01 0.963 – 1.05 0.806 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.993 0.913 – 1.08 0.862 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.02 0.961 – 1.09 0.496 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 1 0.785 – 1.28 0.977 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.99 0.929 – 1.05 0.749 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.02 0.907 – 1.15 0.741 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.23 1.07 – 1.41 0.00297 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.16 0.988 – 1.36 0.0708 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.06 0.999 – 1.12 0.0528 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.996 0.953 – 1.04 0.861 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.871 0.671 – 1.13 0.298 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.892 0.783 – 1.02 0.0854 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1 0.825 – 1.21 0.992 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.06 0.92 – 1.22 0.417 193 1922 all phecode
650 Normal delivery Pregnancy Complications 0.964 0.919 – 1.01 0.135 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 1.03 0.92 – 1.15 0.633 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1.05 0.995 – 1.1 0.0787 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.997 0.943 – 1.05 0.924 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.14 0.908 – 1.44 0.253 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1 0.968 – 1.03 0.985 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.971 0.795 – 1.19 0.776 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.995 0.952 – 1.04 0.815 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.959 0.875 – 1.05 0.371 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.982 0.952 – 1.01 0.23 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.01 0.971 – 1.06 0.564 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.08 0.918 – 1.26 0.361 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.997 0.877 – 1.13 0.968 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.08 0.83 – 1.39 0.579 63 624 all phecode
679 Complications of in utero procedures Dermatologic 1.25 0.955 – 1.63 0.104 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.04 1.02 – 1.07 0.000987 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.02 0.939 – 1.12 0.593 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.05 0.958 – 1.15 0.296 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.04 1.01 – 1.07 0.0102 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.04 1.01 – 1.07 0.0103 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.04 1.01 – 1.07 0.00818 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.09 1 – 1.19 0.0422 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.12 1.06 – 1.18 0.000105 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.06 1.01 – 1.1 0.00971 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 1.03 0.95 – 1.13 0.439 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 1.09 0.982 – 1.22 0.105 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1.05 0.956 – 1.14 0.33 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.05 1 – 1.1 0.0319 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 0.99 0.876 – 1.12 0.879 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 1.11 0.912 – 1.35 0.302 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.03 0.994 – 1.07 0.0971 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.1 1.07 – 1.13 1.6e-11 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 1.1 0.879 – 1.38 0.399 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 1.12 0.862 – 1.44 0.404 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 1.2 1 – 1.44 0.0462 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 1.11 1.04 – 1.19 0.00118 986 9854 all phecode
694.1 Vitiligo Dermatologic 0.867 0.652 – 1.15 0.328 60 599 all phecode
694.2 Other dyschromia Dermatologic 1.15 1.07 – 1.23 0.000166 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 1.08 0.903 – 1.3 0.386 117 1170 all phecode
695 Erythematous conditions Dermatologic 1.05 1.01 – 1.1 0.0165 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 1.08 0.889 – 1.31 0.45 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 1.12 0.944 – 1.33 0.193 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 1.2 0.929 – 1.55 0.163 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.14 0.901 – 1.45 0.27 73 727 all phecode
695.3 Rosacea Dermatologic 1.12 1 – 1.25 0.0484 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.04 0.941 – 1.15 0.449 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.06 0.895 – 1.26 0.484 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.01 0.901 – 1.12 0.913 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 0.995 0.923 – 1.07 0.896 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 1.1 0.964 – 1.26 0.155 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 0.919 0.723 – 1.17 0.494 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.07 0.97 – 1.17 0.182 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 1.01 0.971 – 1.06 0.527 2252 22509 all phecode
696.4 Psoriasis Dermatologic 1.02 0.974 – 1.06 0.433 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.03 0.977 – 1.08 0.298 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.02 0.942 – 1.1 0.643 706 7052 all phecode
697 Sarcoidosis Dermatologic 0.98 0.896 – 1.07 0.66 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 1.04 0.966 – 1.12 0.294 782 7814 all phecode
700 Corns and callosities Dermatologic 1.03 0.912 – 1.17 0.629 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.11 1.07 – 1.14 2.67e-11 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 1.1 0.885 – 1.37 0.391 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.13 1.09 – 1.18 5.29e-09 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.03 0.8 – 1.33 0.81 61 610 all phecode
701.4 Keloid scar Dermatologic 1.15 1.01 – 1.33 0.0421 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.05 0.949 – 1.16 0.359 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.2 0.978 – 1.46 0.0815 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.19 1.15 – 1.22 1.6e-34 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 1.34 1.29 – 1.4 3.2e-49 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 1.08 1.04 – 1.12 3.92e-05 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 1.01 0.909 – 1.13 0.813 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 1.05 0.986 – 1.13 0.124 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 1.07 1.04 – 1.1 4.57e-06 5267 52727 all phecode
704.1 Alopecia Dermatologic 0.906 0.752 – 1.09 0.299 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.977 0.769 – 1.24 0.848 76 759 all phecode
705 Disorders of sweat glands Dermatologic 1.03 0.904 – 1.18 0.627 228 2287 all phecode
705.3 Hidradenitis Dermatologic 1.02 0.884 – 1.18 0.758 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 1.01 0.93 – 1.1 0.767 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 1.07 1.05 – 1.09 6.24e-09 8317 83195 all phecode
706.1 Acne Dermatologic 0.898 0.707 – 1.14 0.379 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 1.08 1.05 – 1.1 6.3e-11 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 1.03 0.987 – 1.08 0.164 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 1.04 0.971 – 1.11 0.263 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.982 0.947 – 1.02 0.322 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 1.01 0.916 – 1.1 0.905 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 1.01 0.864 – 1.18 0.895 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.32 1.04 – 1.67 0.0231 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.978 0.94 – 1.02 0.288 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.05 0.963 – 1.14 0.285 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 1.07 0.982 – 1.17 0.119 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.04 0.891 – 1.2 0.651 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.1 0.991 – 1.22 0.0749 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.04 0.937 – 1.15 0.47 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.06 0.945 – 1.19 0.319 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.06 0.853 – 1.33 0.586 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.962 0.809 – 1.14 0.657 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1 0.778 – 1.29 0.982 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.03 0.997 – 1.06 0.0766 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.04 1.01 – 1.07 0.0221 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.996 0.946 – 1.05 0.891 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.1 0.902 – 1.35 0.342 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.935 0.859 – 1.02 0.125 618 6177 all phecode
716 Other arthropathies Musculoskeletal 1.01 0.999 – 1.02 0.072 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.04 1.01 – 1.08 0.0206 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.02 1 – 1.03 0.0434 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.01 0.999 – 1.02 0.0619 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.02 0.961 – 1.09 0.49 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 1 0.971 – 1.04 0.791 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1.04 1.01 – 1.06 0.00239 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.04 1.01 – 1.07 0.0154 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.996 0.857 – 1.16 0.961 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.06 0.946 – 1.18 0.328 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 0.992 0.971 – 1.01 0.498 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.12 1.03 – 1.23 0.0101 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.01 0.974 – 1.05 0.53 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.18 0.914 – 1.53 0.204 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.982 0.951 – 1.01 0.26 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 0.912 0.831 – 1 0.0528 517 5173 all phecode
723.1 Torticollis Musculoskeletal 1.08 0.885 – 1.32 0.444 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.01 0.967 – 1.06 0.598 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 0.976 0.88 – 1.08 0.643 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 0.971 0.876 – 1.08 0.573 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.12 0.865 – 1.45 0.392 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.02 0.969 – 1.07 0.436 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.01 0.993 – 1.03 0.228 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 1.02 0.997 – 1.04 0.0956 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 0.911 0.812 – 1.02 0.116 334 3336 all phecode
726.3 Bursitis Musculoskeletal 0.987 0.919 – 1.06 0.716 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1 0.978 – 1.03 0.853 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.01 0.971 – 1.05 0.606 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 1.06 0.875 – 1.29 0.549 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.977 0.941 – 1.01 0.223 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 1.02 0.932 – 1.11 0.721 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.958 0.855 – 1.07 0.462 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.04 0.874 – 1.24 0.663 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.02 0.987 – 1.06 0.232 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.987 0.892 – 1.09 0.807 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 1.03 0.995 – 1.06 0.101 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.03 0.993 – 1.07 0.115 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 1 0.974 – 1.03 0.957 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.03 0.965 – 1.1 0.375 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 0.872 0.707 – 1.08 0.202 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.962 0.849 – 1.09 0.549 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.986 0.867 – 1.12 0.826 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 0.927 0.841 – 1.02 0.125 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.891 0.77 – 1.03 0.122 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.975 0.74 – 1.28 0.855 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.01 0.957 – 1.06 0.818 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 0.939 0.833 – 1.06 0.304 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.03 0.942 – 1.13 0.52 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 1.09 0.908 – 1.32 0.345 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.996 0.938 – 1.06 0.886 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 1.07 0.888 – 1.29 0.474 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 1.01 0.986 – 1.03 0.489 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 1.03 0.88 – 1.2 0.729 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 1.01 0.984 – 1.04 0.377 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.995 0.949 – 1.04 0.847 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 1.04 0.983 – 1.09 0.184 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.01 0.98 – 1.03 0.66 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.99 0.94 – 1.04 0.701 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.12 0.986 – 1.28 0.0816 248 2476 all phecode
737 Curvature of spine Musculoskeletal 1.09 1.03 – 1.16 0.0044 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.08 1.02 – 1.15 0.0114 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.01 0.961 – 1.06 0.73 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.02 0.968 – 1.08 0.431 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 1.09 0.994 – 1.2 0.0654 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 1.01 1 – 1.03 0.026 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.01 0.998 – 1.03 0.0829 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.02 0.996 – 1.04 0.1 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.1 0.987 – 1.23 0.0831 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.1 1.02 – 1.2 0.0186 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.02 1 – 1.04 0.0144 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1 0.969 – 1.04 0.847 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 1.22 1.01 – 1.48 0.04 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 1.01 0.932 – 1.1 0.768 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 0.997 0.843 – 1.18 0.973 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 0.981 0.929 – 1.04 0.505 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 0.888 0.727 – 1.08 0.245 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 1.06 0.798 – 1.4 0.704 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.01 0.967 – 1.05 0.77 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 0.877 0.78 – 0.987 0.0295 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.1 0.899 – 1.36 0.343 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 0.964 0.88 – 1.06 0.431 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 1.03 0.981 – 1.08 0.241 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.03 1 – 1.05 0.0297 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 1.03 1.01 – 1.06 0.0159 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 1.03 0.997 – 1.05 0.0752 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1.03 0.942 – 1.12 0.53 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 1.03 0.941 – 1.13 0.509 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.992 0.922 – 1.07 0.822 815 8144 all phecode
745 Pain in joint Musculoskeletal 1.02 0.995 – 1.04 0.118 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.969 0.931 – 1.01 0.117 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.965 0.926 – 1.01 0.0901 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.999 0.917 – 1.09 0.991 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.963 0.838 – 1.11 0.595 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.944 0.899 – 0.992 0.0228 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.01 0.864 – 1.19 0.86 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1 0.751 – 1.33 0.995 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.964 0.855 – 1.09 0.548 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 1.03 0.956 – 1.12 0.398 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.96 0.855 – 1.08 0.495 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.951 0.818 – 1.11 0.515 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.1 0.985 – 1.22 0.0907 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.08 0.94 – 1.23 0.29 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.18 0.976 – 1.43 0.0866 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.03 0.978 – 1.09 0.257 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.01 0.93 – 1.09 0.865 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.02 0.924 – 1.12 0.707 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.979 0.851 – 1.13 0.766 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.04 0.965 – 1.11 0.329 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 1.03 0.928 – 1.13 0.617 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.04 0.927 – 1.17 0.497 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.04 0.933 – 1.17 0.452 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 1.07 0.939 – 1.21 0.32 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 1.15 1 – 1.32 0.0447 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.09 0.873 – 1.36 0.444 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.787 0.644 – 0.962 0.0194 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.833 0.638 – 1.09 0.18 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.06 0.876 – 1.29 0.528 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.08 0.978 – 1.19 0.127 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.13 0.984 – 1.29 0.0829 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.02 0.865 – 1.2 0.834 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.952 0.777 – 1.17 0.636 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.04 0.95 – 1.13 0.421 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.07 0.859 – 1.34 0.536 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.01 0.913 – 1.12 0.846 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.989 0.831 – 1.18 0.905 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.959 0.733 – 1.25 0.76 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.05 0.916 – 1.21 0.471 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.949 0.766 – 1.18 0.633 96 959 all phecode
760 Back pain Symptoms 1.01 0.99 – 1.03 0.32 11126 111353 all phecode
761 Cervicalgia Symptoms 1.04 0.986 – 1.09 0.16 1791 17901 all phecode
764 Sciatica Symptoms 0.964 0.924 – 1.01 0.0982 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.956 0.899 – 1.02 0.148 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 1.07 0.984 – 1.16 0.115 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.01 0.943 – 1.09 0.748 870 8687 all phecode
771.1 Swelling of limb Symptoms 0.996 0.966 – 1.03 0.795 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 1.08 1 – 1.17 0.0458 659 6581 all phecode
773 Pain in limb Symptoms 1.02 0.998 – 1.05 0.072 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 1.05 0.896 – 1.23 0.547 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.991 0.945 – 1.04 0.729 1870 18715 all phecode
782.3 Edema Symptoms 1.04 0.992 – 1.1 0.102 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 1.11 0.95 – 1.29 0.189 175 1748 all phecode
783 Fever of unknown origin Symptoms 0.986 0.954 – 1.02 0.418 3911 39105 all phecode
785 Abdominal pain Symptoms 1.02 1.01 – 1.03 0.0017 40080 301686 all phecode
788 Syncope and collapse Symptoms 1.04 1.02 – 1.06 0.000342 9069 90813 all phecode
789 Nausea and vomiting Symptoms 1.04 1.02 – 1.06 4.75e-05 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.05 0.887 – 1.25 0.554 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 1.12 0.891 – 1.4 0.337 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 1 0.978 – 1.03 0.744 6357 63635 all phecode
791 Gangrene Symptoms 0.857 0.781 – 0.94 0.00108 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1.17 0.965 – 1.42 0.109 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.01 0.84 – 1.21 0.94 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.04 0.951 – 1.13 0.415 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.949 0.783 – 1.15 0.594 120 1198 all phecode
797 Shock Symptoms 0.885 0.746 – 1.05 0.162 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 0.826 0.666 – 1.02 0.0809 102 1020 all phecode
798 Malaise and fatigue Symptoms 1.02 0.982 – 1.05 0.331 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 0.983 0.902 – 1.07 0.703 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 1.01 0.987 – 1.04 0.342 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.997 0.949 – 1.05 0.915 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.889 0.754 – 1.05 0.16 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.02 0.972 – 1.06 0.487 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 0.962 0.892 – 1.04 0.313 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.03 0.99 – 1.08 0.13 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.06 1.01 – 1.12 0.0123 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.979 0.906 – 1.06 0.602 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 1.02 0.999 – 1.05 0.0579 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.04 0.988 – 1.09 0.141 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.02 0.99 – 1.05 0.209 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.05 0.991 – 1.1 0.102 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.995 0.96 – 1.03 0.797 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.06 1 – 1.12 0.0431 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 1.08 1.01 – 1.17 0.0312 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.06 1 – 1.12 0.0404 1300 12998 all phecode
817 Concussion Injuries & Poisonings 1.26 1.11 – 1.44 0.000476 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.96 0.876 – 1.05 0.378 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.01 0.975 – 1.05 0.514 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 1.03 0.975 – 1.08 0.32 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 1.03 0.983 – 1.08 0.224 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 1.01 0.99 – 1.02 0.457 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.04 0.954 – 1.14 0.35 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 1 0.91 – 1.1 0.962 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.06 1.03 – 1.09 5.35e-05 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.02 0.862 – 1.2 0.846 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.02 0.928 – 1.11 0.723 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.01 0.959 – 1.06 0.814 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.992 0.935 – 1.05 0.783 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1 0.966 – 1.04 0.881 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.02 0.986 – 1.06 0.238 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 0.962 0.751 – 1.23 0.758 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.04 1 – 1.07 0.0471 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.04 0.917 – 1.17 0.554 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 1.06 0.921 – 1.22 0.406 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.04 0.997 – 1.08 0.0741 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.07 0.933 – 1.23 0.326 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 1 0.767 – 1.31 0.985 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 0.987 0.955 – 1.02 0.428 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.18 0.904 – 1.54 0.224 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.13 0.922 – 1.38 0.241 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.99 0.849 – 1.15 0.896 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 0.978 0.889 – 1.08 0.643 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 0.907 0.792 – 1.04 0.163 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.01 0.866 – 1.18 0.884 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 0.997 0.848 – 1.17 0.968 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 0.99 0.935 – 1.05 0.74 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.05 1.02 – 1.08 0.00279 4260 42663 all phecode
916 Contusion Injuries & Poisonings 1.04 0.984 – 1.1 0.169 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.939 0.801 – 1.1 0.44 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.29 1.17 – 1.43 8.69e-07 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 1.34 1.18 – 1.52 4.49e-06 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.04 0.99 – 1.08 0.13 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.921 0.801 – 1.06 0.25 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.998 0.818 – 1.22 0.981 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.06 0.968 – 1.16 0.216 550 5509 all phecode
947 Urticaria Injuries & Poisonings 1.05 0.94 – 1.17 0.397 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 1.09 0.985 – 1.21 0.0959 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.13 1.02 – 1.25 0.0167 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.972 0.856 – 1.1 0.656 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.969 0.881 – 1.06 0.505 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.01 0.76 – 1.34 0.95 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.765 0.597 – 0.981 0.035 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.01 0.994 – 1.03 0.24 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1 0.986 – 1.02 0.783 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.06 0.961 – 1.17 0.237 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.05 0.98 – 1.13 0.161 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.08 0.974 – 1.2 0.143 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.06 0.95 – 1.18 0.304 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.955 0.829 – 1.1 0.517 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.999 0.882 – 1.13 0.988 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.03 0.906 – 1.16 0.675 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.991 0.965 – 1.02 0.528 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.984 – 1.11 0.146 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.07 0.976 – 1.18 0.15 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.06 0.959 – 1.18 0.245 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.02 0.929 – 1.11 0.711 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.996 0.913 – 1.09 0.926 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1 0.957 – 1.05 0.908 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.929 0.797 – 1.08 0.349 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.985 0.867 – 1.12 0.816 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.991 0.79 – 1.24 0.935 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.12 0.924 – 1.37 0.243 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.927 0.752 – 1.14 0.482 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.923 0.713 – 1.19 0.541 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.98 0.744 – 1.29 0.885 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.11 0.967 – 1.27 0.139 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.03 0.957 – 1.12 0.388 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.936 0.805 – 1.09 0.387 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.14 0.878 – 1.48 0.326 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.23 1.01 – 1.5 0.0396 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.777 0.63 – 0.958 0.0184 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.956 0.765 – 1.2 0.695 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.02 0.985 – 1.06 0.25 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.01 0.976 – 1.05 0.471 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 1.01 0.976 – 1.05 0.471 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 1.01 0.987 – 1.03 0.408 8412 85066 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.02 0.976 – 1.06 0.439 2590 26097 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.07 0.987 – 1.16 0.0997 607 6267 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1 0.931 – 1.08 0.978 808 8275 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.18 0.899 – 1.56 0.23 53 533 exclusion phecode
010 Tuberculosis Infectious Diseases 0.927 0.785 – 1.09 0.367 160 1591 exclusion phecode
038 Septicemia Infectious Diseases 1.01 0.975 – 1.04 0.624 3950 40058 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.02 0.952 – 1.1 0.528 803 8157 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 0.981 0.89 – 1.08 0.69 473 4756 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.01 0.989 – 1.03 0.421 11405 115675 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.03 0.995 – 1.07 0.0876 2961 30113 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 0.978 0.927 – 1.03 0.415 1554 15843 exclusion phecode
041.4 E. coli Infectious Diseases 1 0.96 – 1.04 0.975 2597 26247 exclusion phecode
053 Herpes zoster Infectious Diseases 0.98 0.882 – 1.09 0.706 391 3973 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1 0.807 – 1.24 0.998 94 917 exclusion phecode
054 Herpes simplex Infectious Diseases 1.08 0.936 – 1.24 0.301 203 2046 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.08 0.987 – 1.17 0.0946 564 5729 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 0.912 0.702 – 1.18 0.488 66 665 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 1.15 0.965 – 1.38 0.118 123 1288 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.11 0.974 – 1.26 0.119 247 2508 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 0.994 0.872 – 1.13 0.924 253 2668 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.02 0.92 – 1.13 0.727 403 4124 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.03 0.866 – 1.22 0.74 137 1434 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.05 0.873 – 1.27 0.585 109 1140 exclusion phecode
078 Viral warts & HPV Infectious Diseases 1.08 1.01 – 1.15 0.0234 913 9745 exclusion phecode
079 Viral infection Infectious Diseases 0.993 0.953 – 1.03 0.723 2656 26812 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.977 0.758 – 1.26 0.856 60 626 exclusion phecode
080 Postoperative infection Infectious Diseases 1.02 0.987 – 1.05 0.259 4234 43158 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.04 0.999 – 1.09 0.0553 2353 23841 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.18 0.935 – 1.5 0.161 68 686 exclusion phecode
1000 Burns Injuries & Poisonings 0.974 0.892 – 1.06 0.56 563 5594 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 1.07 1.01 – 1.13 0.0339 1144 11630 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 0.994 0.966 – 1.02 0.7 5237 52687 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.06 0.939 – 1.2 0.346 292 2882 exclusion phecode
1005 Other symptoms Injuries & Poisonings 1.01 0.957 – 1.07 0.672 1375 13869 exclusion phecode
1006 Crushing injury Injuries & Poisonings 0.949 0.832 – 1.08 0.442 245 2476 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 1.03 0.905 – 1.18 0.641 249 2478 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.03 0.965 – 1.1 0.353 964 9771 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 1.02 0.998 – 1.04 0.0711 8207 82098 exclusion phecode
1010 Other tests Injuries & Poisonings 1.02 0.99 – 1.05 0.215 5692 57250 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.01 0.987 – 1.03 0.438 8702 87961 exclusion phecode
1012 Late effect Injuries & Poisonings 1.05 0.864 – 1.27 0.63 102 1014 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.02 0.907 – 1.15 0.732 305 3051 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.998 0.77 – 1.29 0.989 64 632 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 1.02 0.984 – 1.05 0.313 4026 40821 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.01 0.989 – 1.02 0.488 14883 153567 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.923 0.811 – 1.05 0.221 264 2722 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.917 0.805 – 1.04 0.194 258 2667 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.17 0.922 – 1.48 0.197 67 725 exclusion phecode
110.12 Althete's foot Infectious Diseases 0.795 0.661 – 0.955 0.0141 134 1370 exclusion phecode
112 Candidiasis Infectious Diseases 1.04 0.99 – 1.08 0.128 2020 20395 exclusion phecode
117 Mycoses Infectious Diseases 0.907 0.795 – 1.03 0.145 261 2624 exclusion phecode
117.4 Aspergillosis Infectious Diseases 0.863 0.729 – 1.02 0.0903 161 1591 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.898 0.707 – 1.14 0.378 80 764 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 0.999 0.763 – 1.31 0.991 62 668 exclusion phecode
134 Helminthiases Infectious Diseases 1.17 0.979 – 1.4 0.0847 123 1225 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.15 0.954 – 1.39 0.141 103 1028 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.994 0.855 – 1.15 0.933 193 1974 exclusion phecode
145 Cancer of mouth Neoplasms 0.99 0.909 – 1.08 0.818 583 6143 exclusion phecode
145.2 Cancer of tongue Neoplasms 0.856 0.758 – 0.967 0.0126 294 2982 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 1.17 0.951 – 1.43 0.138 96 1009 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.01 0.763 – 1.34 0.938 52 510 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.01 0.93 – 1.1 0.785 593 6064 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 0.949 0.826 – 1.09 0.461 238 2405 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.11 0.975 – 1.25 0.117 252 2503 exclusion phecode
150 Cancer of esophagus Neoplasms 0.973 0.901 – 1.05 0.491 727 7280 exclusion phecode
151 Cancer of stomach Neoplasms 0.919 0.839 – 1.01 0.0669 545 5416 exclusion phecode
153 Colorectal cancer Neoplasms 0.989 0.958 – 1.02 0.5 4289 43805 exclusion phecode
153.2 Colon cancer Neoplasms 0.995 0.958 – 1.03 0.811 2922 29675 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.986 0.941 – 1.03 0.56 2018 20705 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.981 0.882 – 1.09 0.727 382 3822 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.07 0.905 – 1.27 0.422 149 1509 exclusion phecode
157 Pancreatic cancer Neoplasms 0.949 0.873 – 1.03 0.226 633 6289 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.01 0.945 – 1.08 0.803 999 10182 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.985 0.957 – 1.01 0.319 5198 53215 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.04 0.892 – 1.21 0.619 181 1819 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.863 0.741 – 1 0.0578 194 1950 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.03 0.887 – 1.21 0.669 185 1841 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 1.34 1.03 – 1.74 0.0303 58 573 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.05 1.01 – 1.1 0.0124 2668 26957 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.05 1.01 – 1.1 0.0257 2121 21338 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 1.03 0.932 – 1.15 0.521 385 4177 exclusion phecode
170.1 Bone cancer Neoplasms 1.16 0.964 – 1.4 0.115 118 1245 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1 0.888 – 1.13 0.978 292 3183 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.07 0.903 – 1.28 0.422 137 1818 exclusion phecode
174 Breast cancer Neoplasms 1.02 0.997 – 1.04 0.0963 12111 122349 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1.02 0.998 – 1.04 0.0786 11917 120336 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.02 1 – 1.04 0.0529 11228 113531 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.984 0.807 – 1.2 0.877 111 1111 exclusion phecode
175 Acquired absence of breast Neoplasms 1.02 0.981 – 1.07 0.28 2282 23220 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 0.993 0.948 – 1.04 0.751 2119 21229 exclusion phecode
180.1 Cervical cancer Neoplasms 0.98 0.863 – 1.11 0.755 268 2640 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.995 0.95 – 1.04 0.828 2025 20287 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.975 0.919 – 1.03 0.399 1226 12355 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.02 0.963 – 1.08 0.495 1303 13299 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.05 0.986 – 1.13 0.121 926 9332 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.05 0.979 – 1.12 0.176 899 9058 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.949 0.837 – 1.08 0.41 279 2963 exclusion phecode
185 Cancer of prostate Neoplasms 0.998 0.971 – 1.03 0.908 5586 55793 exclusion phecode
187 Cancer of other male genital organs Neoplasms 0.998 0.903 – 1.1 0.968 425 4350 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.05 0.812 – 1.36 0.712 60 675 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 1.04 0.921 – 1.17 0.534 277 2799 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.989 0.811 – 1.21 0.912 107 1048 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.01 0.976 – 1.04 0.604 3923 39646 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.01 0.943 – 1.08 0.821 1016 10245 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1 0.937 – 1.07 0.943 983 9870 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.1 0.843 – 1.43 0.485 58 622 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.02 0.978 – 1.07 0.328 2284 22927 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1 0.959 – 1.05 0.844 2032 20386 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.06 0.888 – 1.27 0.51 129 1369 exclusion phecode
190 Cancer of eye Neoplasms 1.24 1.06 – 1.46 0.00774 147 1679 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.02 0.944 – 1.11 0.572 661 6593 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 1.03 0.941 – 1.12 0.539 543 5411 exclusion phecode
191.11 Cancer of brain Neoplasms 1.03 0.935 – 1.13 0.587 503 5023 exclusion phecode
193 Thyroid cancer Neoplasms 1.06 0.948 – 1.18 0.304 327 3350 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 0.967 0.775 – 1.21 0.768 91 909 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.03 1.01 – 1.05 0.00303 13554 160056 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.03 1.01 – 1.04 0.00546 12892 154276 exclusion phecode
197 Chemotherapy Neoplasms 1.02 1.01 – 1.04 0.00163 20337 206935 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.01 0.991 – 1.04 0.258 8817 92416 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.02 0.993 – 1.05 0.14 4917 52033 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.01 0.965 – 1.06 0.667 2068 21940 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.993 0.94 – 1.05 0.805 1435 15001 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.01 0.974 – 1.06 0.483 2495 25756 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.02 0.948 – 1.1 0.561 755 8236 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.02 0.97 – 1.06 0.498 2029 20888 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.07 0.888 – 1.29 0.479 114 1836 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.01 0.959 – 1.07 0.616 1346 13849 exclusion phecode
199.4 Neurofibromatosis Neoplasms 0.856 0.679 – 1.08 0.187 92 929 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.02 0.955 – 1.09 0.526 920 9480 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.01 0.906 – 1.13 0.845 365 3692 exclusion phecode
201 Hodgkin's disease Neoplasms 1.06 0.933 – 1.21 0.366 250 2507 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.01 0.963 – 1.05 0.743 2068 21780 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.03 0.975 – 1.08 0.334 1664 17309 exclusion phecode
202.21 Nodular lymphoma Neoplasms 0.931 0.829 – 1.05 0.232 338 3500 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.07 0.975 – 1.16 0.16 540 5562 exclusion phecode
204 Leukemia Neoplasms 1.03 0.978 – 1.09 0.248 1518 15908 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1.06 0.97 – 1.16 0.198 514 5524 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.901 0.669 – 1.21 0.494 53 545 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.08 0.985 – 1.19 0.0986 449 4844 exclusion phecode
204.2 Myeloid leukemia Neoplasms 0.96 0.867 – 1.06 0.432 435 4437 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.993 0.88 – 1.12 0.905 312 3151 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.928 0.773 – 1.11 0.426 131 1392 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.14 1.04 – 1.25 0.00373 515 5338 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1.03 1.01 – 1.05 0.000133 18851 184234 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.03 0.959 – 1.1 0.449 949 9456 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.04 1.01 – 1.07 0.0197 5005 50355 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.975 0.869 – 1.09 0.671 335 3331 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.16 1.03 – 1.3 0.0137 307 3109 exclusion phecode
214 Lipoma Neoplasms 1 0.974 – 1.03 0.987 5928 60147 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.997 0.966 – 1.03 0.837 4355 44315 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.998 0.935 – 1.06 0.941 1048 10681 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.91 0.886 – 0.934 1.7e-12 6446 74370 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.06 0.969 – 1.15 0.214 565 6102 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 1.06 0.971 – 1.16 0.192 531 5747 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.994 0.973 – 1.02 0.562 9703 97465 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 1 0.983 – 1.02 0.737 9913 99546 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.903 0.801 – 1.02 0.092 337 3457 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 1.05 0.995 – 1.11 0.0748 1396 14013 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.01 0.872 – 1.17 0.909 206 2124 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.888 0.747 – 1.06 0.18 154 1535 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.966 0.823 – 1.14 0.677 166 1658 exclusion phecode
224 Benign neoplasm of eye Neoplasms 1.19 0.993 – 1.42 0.0599 123 1229 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.36 1.07 – 1.74 0.0124 65 640 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.994 0.923 – 1.07 0.883 777 7865 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.993 0.919 – 1.07 0.857 736 7482 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.02 0.787 – 1.31 0.896 59 561 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.1 0.966 – 1.25 0.154 255 2581 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.01 0.942 – 1.09 0.719 819 8320 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.12 0.963 – 1.31 0.139 178 1782 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.07 0.954 – 1.19 0.261 350 3573 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.941 0.833 – 1.06 0.33 295 2993 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.03 0.972 – 1.08 0.346 1462 15403 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.82 0.782 – 0.86 2.56e-16 2100 23224 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.955 0.874 – 1.04 0.307 569 5799 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.01 0.945 – 1.08 0.807 1035 10684 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.956 0.867 – 1.06 0.375 442 4527 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.08 0.993 – 1.17 0.0736 631 6534 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.04 0.988 – 1.09 0.141 1785 17871 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 1.02 0.926 – 1.13 0.673 436 4416 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.19 0.973 – 1.44 0.0911 90 887 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 1.05 0.874 – 1.25 0.623 135 1338 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.02 1 – 1.04 0.0273 13973 139766 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.01 0.948 – 1.08 0.735 1034 10691 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.07 0.868 – 1.32 0.527 96 965 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.02 1 – 1.04 0.0234 13343 133846 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.991 0.874 – 1.12 0.885 280 2777 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.04 0.9 – 1.2 0.615 212 2102 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.03 0.889 – 1.19 0.705 205 2027 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1 0.902 – 1.12 0.949 376 3821 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.02 1.01 – 1.04 0.00262 18796 178526 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.05 1 – 1.09 0.0304 2644 26570 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.07 0.94 – 1.23 0.297 233 2312 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.13 0.889 – 1.43 0.326 74 743 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.996 0.903 – 1.1 0.928 461 4547 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.08 0.917 – 1.27 0.357 156 1546 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.02 1.01 – 1.04 0.00886 16911 163105 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.15 0.944 – 1.39 0.168 99 1010 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.998 0.861 – 1.16 0.978 192 1926 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.999 0.933 – 1.07 0.974 934 9450 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1 0.91 – 1.1 0.987 479 4844 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.01 0.928 – 1.09 0.872 647 6550 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.05 0.922 – 1.2 0.46 248 2537 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.988 0.891 – 1.1 0.821 400 4026 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.964 0.8 – 1.16 0.702 130 1269 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1 0.891 – 1.12 1 333 3358 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.979 0.923 – 1.04 0.486 1268 12749 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.07 1 – 1.15 0.0446 898 8982 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.989 0.92 – 1.06 0.776 815 8406 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.977 0.905 – 1.06 0.559 729 7509 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.93 0.774 – 1.12 0.442 131 1373 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.989 0.911 – 1.07 0.796 647 6546 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.901 0.768 – 1.06 0.203 176 1799 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.96 0.77 – 1.2 0.721 89 908 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.05 0.919 – 1.2 0.475 245 2530 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.1 0.879 – 1.38 0.405 90 889 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.04 0.882 – 1.23 0.624 151 1502 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.916 0.842 – 0.997 0.0435 612 6160 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.07 0.914 – 1.25 0.408 171 1733 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.01 0.819 – 1.24 0.946 99 993 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.21 0.959 – 1.52 0.108 72 734 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.858 0.767 – 0.961 0.00807 343 3498 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.857 0.766 – 0.96 0.00768 342 3490 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.954 0.831 – 1.09 0.5 234 2364 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.903 0.778 – 1.05 0.175 204 2062 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1.21 1.02 – 1.44 0.0271 150 1561 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.17 0.988 – 1.4 0.0679 143 1483 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.974 0.794 – 1.2 0.802 99 972 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 1.14 0.965 – 1.35 0.122 144 1448 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.06 0.919 – 1.22 0.424 189 1948 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.06 0.982 – 1.14 0.141 785 8013 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.02 0.964 – 1.09 0.43 1142 11533 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.02 0.946 – 1.1 0.597 724 7251 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.02 0.923 – 1.13 0.701 421 4301 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.891 0.702 – 1.13 0.341 73 739 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.05 0.918 – 1.2 0.477 232 2331 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.09 0.972 – 1.22 0.143 324 3241 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.09 0.966 – 1.23 0.16 276 2888 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.05 0.924 – 1.2 0.434 236 2481 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.09 0.936 – 1.26 0.273 179 1803 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1.08 0.889 – 1.32 0.427 108 1078 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.969 0.74 – 1.27 0.818 57 659 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.919 0.771 – 1.1 0.349 149 1544 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.913 0.756 – 1.1 0.345 129 1341 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.01 0.998 – 1.02 0.11 32927 226850 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.01 0.998 – 1.02 0.122 32866 226625 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.01 0.995 – 1.02 0.223 30544 219659 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.13 0.862 – 1.48 0.379 57 544 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.936 0.793 – 1.1 0.433 159 1578 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.11 0.953 – 1.29 0.18 196 2023 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1 0.966 – 1.04 0.977 3503 35620 exclusion phecode
274.1 Gout Endocrine/metabolic 0.997 0.96 – 1.04 0.88 2970 30292 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.01 0.833 – 1.24 0.889 107 1079 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.02 0.938 – 1.12 0.609 589 5881 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.03 0.942 – 1.13 0.503 537 5354 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.04 0.998 – 1.09 0.0626 1979 20209 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 1.05 0.963 – 1.14 0.287 617 6267 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.07 0.961 – 1.2 0.213 345 3594 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.06 1 – 1.13 0.046 1132 11535 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.14 0.964 – 1.35 0.126 157 1643 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.03 1 – 1.05 0.0436 6899 69742 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.01 0.978 – 1.05 0.51 3866 39125 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.983 0.858 – 1.13 0.805 230 2304 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.02 0.968 – 1.07 0.504 1733 17384 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.05 0.976 – 1.12 0.205 904 9281 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1 0.949 – 1.06 0.878 1341 13659 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.03 0.967 – 1.1 0.365 1103 11125 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.04 0.973 – 1.11 0.246 1002 10127 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 0.902 0.731 – 1.11 0.34 108 1080 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.04 0.999 – 1.08 0.0558 2682 27012 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.01 0.911 – 1.11 0.88 413 4323 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 0.98 0.816 – 1.18 0.827 122 1245 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.01 0.943 – 1.09 0.721 860 8589 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.993 0.888 – 1.11 0.907 353 3448 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.02 0.888 – 1.17 0.769 219 2196 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.02 1 – 1.04 0.0324 10383 104493 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.02 1 – 1.04 0.0315 10226 102920 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 0.901 0.712 – 1.14 0.385 80 818 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.12 0.878 – 1.43 0.358 62 632 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.05 0.918 – 1.21 0.455 233 2428 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.07 0.917 – 1.24 0.409 196 2035 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1 0.839 – 1.2 0.969 130 1341 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 0.955 0.835 – 1.09 0.502 237 2373 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.03 1.01 – 1.06 0.012 7246 73394 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.03 1.01 – 1.06 0.0115 6958 70465 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.1 0.994 – 1.21 0.0662 433 4406 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.11 1.04 – 1.18 0.00156 1068 10696 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.12 1.05 – 1.19 0.000752 1025 10252 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.13 1.05 – 1.22 0.00143 723 7224 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.961 0.815 – 1.13 0.637 167 1711 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 1.11 0.957 – 1.3 0.165 175 1753 exclusion phecode
281.9 Deficiency anemias Hematopoietic 0.917 0.699 – 1.2 0.531 52 519 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 0.991 0.833 – 1.18 0.916 146 1447 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.03 0.786 – 1.35 0.826 55 543 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.935 0.74 – 1.18 0.569 84 819 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 0.937 0.781 – 1.12 0.48 125 1322 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.935 0.762 – 1.15 0.517 97 1016 exclusion phecode
284 Aplastic anemia Hematopoietic 1.06 0.954 – 1.18 0.283 399 4164 exclusion phecode
285 Other anemias Hematopoietic 1.03 1.01 – 1.05 0.00118 11494 116451 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.926 0.81 – 1.06 0.26 255 2619 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.05 0.968 – 1.14 0.247 639 6711 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.06 0.955 – 1.17 0.285 389 3980 exclusion phecode
286 Coagulation defects Hematopoietic 0.98 0.913 – 1.05 0.574 883 8905 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.987 0.892 – 1.09 0.791 442 4441 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.956 0.774 – 1.18 0.677 93 923 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.976 0.861 – 1.11 0.71 283 2850 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 0.996 0.764 – 1.3 0.977 62 603 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.05 0.842 – 1.31 0.674 81 822 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.999 0.896 – 1.11 0.985 370 3735 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.984 0.933 – 1.04 0.555 1549 15843 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.09 0.901 – 1.31 0.387 121 1241 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 0.981 0.928 – 1.04 0.482 1457 14897 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 0.985 0.886 – 1.1 0.786 389 4017 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.982 0.775 – 1.24 0.878 73 729 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1 0.965 – 1.04 0.991 3532 36245 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 0.983 0.945 – 1.02 0.37 2968 30475 exclusion phecode
288.11 Neutropenia Hematopoietic 0.984 0.947 – 1.02 0.421 2976 30557 exclusion phecode
288.3 Eosinophilia Hematopoietic 1.17 0.921 – 1.49 0.199 68 682 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.08 1 – 1.16 0.0451 818 8260 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.05 0.922 – 1.19 0.489 276 2782 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.03 0.987 – 1.07 0.17 2435 25074 exclusion phecode
289.5 Diseases of spleen Hematopoietic 0.976 0.887 – 1.08 0.625 482 4939 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.02 0.895 – 1.15 0.813 280 2803 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.15 0.923 – 1.43 0.215 85 858 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.09 1.04 – 1.14 0.000752 1822 18297 exclusion phecode
290.1 Dementias Mental Disorders 1.12 1.04 – 1.19 0.00156 940 9496 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 1.06 0.957 – 1.18 0.261 406 4090 exclusion phecode
290.16 Vascular dementia Mental Disorders 1.25 1.08 – 1.45 0.00258 186 1895 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.06 0.973 – 1.15 0.188 620 6201 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.06 0.827 – 1.35 0.651 68 691 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.06 0.986 – 1.14 0.117 802 8094 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.89 0.738 – 1.07 0.224 130 1284 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.03 0.906 – 1.16 0.678 273 2747 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.11 1.01 – 1.23 0.0358 417 4232 exclusion phecode
292 Neurological disorders Mental Disorders 1.03 0.995 – 1.06 0.0987 4420 44272 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.07 1.01 – 1.13 0.0192 1439 14469 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 1.01 0.87 – 1.18 0.852 180 1825 exclusion phecode
292.3 Memory loss Mental Disorders 1.03 0.948 – 1.12 0.502 666 6697 exclusion phecode
292.4 Altered mental status Mental Disorders 0.992 0.947 – 1.04 0.722 2087 20833 exclusion phecode
292.6 Hallucinations Mental Disorders 1.13 1.01 – 1.27 0.0394 291 2961 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.04 0.996 – 1.09 0.074 1996 20116 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.07 0.998 – 1.15 0.0554 837 8670 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.02 0.947 – 1.1 0.618 824 8200 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.03 0.943 – 1.12 0.528 564 5612 exclusion phecode
295.2 Paranoid disorders Mental Disorders 0.992 0.848 – 1.16 0.918 177 1721 exclusion phecode
295.3 Psychosis Mental Disorders 0.949 0.805 – 1.12 0.534 164 1655 exclusion phecode
296 Mood disorders Mental Disorders 1.02 1 – 1.04 0.0498 11929 119969 exclusion phecode
296.1 Bipolar Mental Disorders 1.05 0.986 – 1.12 0.129 1025 10309 exclusion phecode
296.2 Depression Mental Disorders 1.02 0.997 – 1.04 0.105 11309 113778 exclusion phecode
296.22 Major depressive disorder Mental Disorders 0.968 0.865 – 1.08 0.569 346 3487 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.987 0.88 – 1.11 0.817 302 2990 exclusion phecode
300 Anxiety disorders Mental Disorders 1.03 1 – 1.06 0.02 6602 66124 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.03 1 – 1.06 0.034 6090 61089 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 1.09 0.916 – 1.31 0.324 141 1451 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.01 0.931 – 1.09 0.835 684 6830 exclusion phecode
300.13 Phobia Mental Disorders 0.981 0.892 – 1.08 0.699 485 4835 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.16 0.975 – 1.38 0.0934 137 1366 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.08 0.814 – 1.45 0.579 52 514 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.12 0.933 – 1.35 0.223 123 1204 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.93 0.767 – 1.13 0.463 112 1099 exclusion phecode
301 Personality disorders Mental Disorders 1.12 1 – 1.26 0.0501 328 3256 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.21 1.01 – 1.45 0.0401 116 1160 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 0.988 0.871 – 1.12 0.852 272 2718 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.11 1.01 – 1.22 0.033 450 4527 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 1.14 1.02 – 1.26 0.0216 339 3400 exclusion phecode
303.4 Somatoform disorder Mental Disorders 1.13 0.945 – 1.35 0.183 118 1193 exclusion phecode
304 Adjustment reaction Mental Disorders 0.998 0.882 – 1.13 0.981 286 2875 exclusion phecode
305.2 Eating disorder Mental Disorders 1.09 0.87 – 1.35 0.468 86 887 exclusion phecode
306 Other mental disorder Mental Disorders 1.02 1.01 – 1.04 0.00061 26690 221620 exclusion phecode
306.9 Tension headache Mental Disorders 1.07 0.954 – 1.21 0.243 305 3045 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.983 0.777 – 1.24 0.887 75 755 exclusion phecode
313.3 Autism Mental Disorders 1.11 0.838 – 1.47 0.469 53 528 exclusion phecode
315 Develomental delays and disorders Mental Disorders 0.976 0.872 – 1.09 0.681 333 3381 exclusion phecode
315.1 Learning disorder Mental Disorders 1.14 0.969 – 1.35 0.112 153 1568 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.989 0.792 – 1.24 0.923 86 840 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.05 1.02 – 1.08 0.00134 5140 51323 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.918 0.693 – 1.22 0.552 56 575 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.04 1.02 – 1.06 5.54e-06 12190 122357 exclusion phecode
317.1 Alcoholism Mental Disorders 1.04 1.02 – 1.06 0.00056 8512 85617 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.06 0.99 – 1.14 0.0931 813 8095 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.02 1 – 1.04 0.0113 18606 179029 exclusion phecode
320 Meningitis Neurological 0.935 0.844 – 1.03 0.192 428 4296 exclusion phecode
323 Encephalitis Neurological 0.951 0.846 – 1.07 0.404 331 3293 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 0.811 0.63 – 1.04 0.104 73 718 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 0.985 0.869 – 1.12 0.817 279 2787 exclusion phecode
327 Sleep disorders Neurological 1.04 0.977 – 1.11 0.225 1115 11220 exclusion phecode
327.3 Sleep apnea Neurological 1.03 0.995 – 1.06 0.104 4252 42671 exclusion phecode
327.4 Insomnia Neurological 1.03 0.873 – 1.23 0.696 147 1594 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.03 0.851 – 1.24 0.786 122 1333 exclusion phecode
331 Other cerebral degenerations Neurological 1.01 0.946 – 1.07 0.804 1089 10943 exclusion phecode
331.1 Hydrocephalus Neurological 0.957 0.868 – 1.05 0.373 481 4830 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.06 0.955 – 1.17 0.285 408 4112 exclusion phecode
332 Parkinson's disease Neurological 1.05 0.98 – 1.12 0.174 1033 10688 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.04 0.971 – 1.12 0.257 843 8622 exclusion phecode
333.1 Essential tremor Neurological 0.986 0.849 – 1.14 0.853 197 2057 exclusion phecode
333.2 Myoclonus Neurological 0.945 0.767 – 1.16 0.595 93 922 exclusion phecode
333.4 Torsion dystonia Neurological 1.1 0.962 – 1.25 0.167 239 2420 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 0.994 0.945 – 1.05 0.805 1732 17414 exclusion phecode
334.1 Spinocerebellar disease Neurological 0.947 0.783 – 1.15 0.578 111 1128 exclusion phecode
334.2 Anterior horn cell disease Neurological 1.03 0.904 – 1.18 0.624 234 2343 exclusion phecode
335 Multiple sclerosis Neurological 0.992 0.936 – 1.05 0.784 1294 12970 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 0.966 0.848 – 1.1 0.602 252 2548 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.03 0.799 – 1.32 0.832 69 681 exclusion phecode
338 Pain Neurological 1.02 0.944 – 1.1 0.639 730 7413 exclusion phecode
338.1 Acute pain Neurological 0.952 0.854 – 1.06 0.373 371 3788 exclusion phecode
338.2 Chronic pain Neurological 1.05 0.949 – 1.17 0.323 365 3691 exclusion phecode
339 Other headache syndromes Neurological 1.02 0.993 – 1.04 0.158 7554 75796 exclusion phecode
340 Migraine Neurological 0.999 0.961 – 1.04 0.977 2766 27738 exclusion phecode
340.1 Migrain with aura Neurological 0.949 0.82 – 1.1 0.487 209 2057 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.998 0.878 – 1.13 0.975 249 2465 exclusion phecode
342 Hemiplegia Neurological 1.01 0.96 – 1.07 0.605 1429 14345 exclusion phecode
343 Infantile cerebral palsy Neurological 1.1 0.924 – 1.3 0.296 141 1414 exclusion phecode
344 Other paralytic syndromes Neurological 1.02 0.943 – 1.11 0.564 635 6332 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.02 0.985 – 1.05 0.315 4797 48477 exclusion phecode
345.1 Epilepsy Neurological 1.01 0.942 – 1.09 0.731 823 8352 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.05 0.955 – 1.16 0.293 422 4237 exclusion phecode
345.12 Partial epilepsy Neurological 0.986 0.871 – 1.12 0.827 270 2678 exclusion phecode
345.3 Convulsions Neurological 1.05 1 – 1.09 0.0502 2142 21515 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.934 0.78 – 1.12 0.459 136 1372 exclusion phecode
348 Other conditions of brain Neurological 1.04 0.965 – 1.12 0.31 752 7537 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.01 0.889 – 1.15 0.877 260 2584 exclusion phecode
348.4 Cerebral cysts Neurological 0.989 0.829 – 1.18 0.901 130 1309 exclusion phecode
348.7 Coma Neurological 1.08 0.964 – 1.2 0.192 346 3458 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.06 0.925 – 1.2 0.425 239 2417 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.08 0.969 – 1.2 0.165 363 3750 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.979 0.874 – 1.1 0.713 326 3297 exclusion phecode
350 Abnormal movement Neurological 1.04 0.999 – 1.08 0.0534 2550 25562 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.01 0.944 – 1.09 0.707 839 8471 exclusion phecode
350.2 Abnormality of gait Neurological 1.07 1.02 – 1.13 0.0108 1534 15228 exclusion phecode
350.3 Lack of coordination Neurological 1.04 0.937 – 1.17 0.429 344 3487 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.993 0.743 – 1.33 0.963 52 516 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.01 0.991 – 1.03 0.28 11955 119916 exclusion phecode
352 Disorders of other cranial nerves Neurological 1 0.945 – 1.06 0.95 1302 13208 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.992 0.898 – 1.1 0.881 444 4476 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.03 0.954 – 1.1 0.501 834 8485 exclusion phecode
353 Nerve root and plexus disorders Neurological 1 0.941 – 1.07 0.932 1084 10872 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.939 0.77 – 1.15 0.537 109 1099 exclusion phecode
353.2 Nerve root lesions Neurological 0.99 0.748 – 1.31 0.942 54 548 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.985 0.834 – 1.16 0.857 147 1450 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 0.962 0.908 – 1.02 0.196 1300 13076 exclusion phecode
358 Myoneural disorders Neurological 1.18 1.02 – 1.35 0.0238 206 2028 exclusion phecode
358.1 Myasthenia gravis Neurological 1.16 1 – 1.34 0.0507 187 1837 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 1.09 0.988 – 1.2 0.0845 446 4488 exclusion phecode
359.1 Muscular dystrophies Neurological 0.984 0.816 – 1.19 0.867 118 1190 exclusion phecode
359.2 Myopathy Neurological 1.13 1.01 – 1.26 0.037 343 3464 exclusion phecode
360 Disorders of the globe Sense Organs 1.11 0.993 – 1.25 0.0667 327 3234 exclusion phecode
360.2 Progressive myopia Sense Organs 1.14 1 – 1.3 0.0461 243 2412 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.99 0.953 – 1.03 0.607 3125 31157 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.02 0.968 – 1.08 0.399 1335 13343 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.795 0.603 – 1.05 0.104 65 655 exclusion phecode
362 Other retinal disorders Sense Organs 1 0.969 – 1.04 0.854 3662 36610 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.01 0.967 – 1.06 0.6 2082 20770 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.01 0.968 – 1.06 0.569 2079 20742 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.986 0.829 – 1.17 0.872 153 1539 exclusion phecode
362.31 Separation of retinal layers Sense Organs 0.996 0.801 – 1.24 0.974 95 943 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.994 0.924 – 1.07 0.881 818 8096 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.988 0.836 – 1.17 0.889 170 1750 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.974 0.768 – 1.24 0.827 80 782 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.02 0.836 – 1.24 0.871 113 1114 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.11 0.941 – 1.31 0.219 162 1625 exclusion phecode
363.3 Chorioretinal scars Sense Organs 1 0.77 – 1.3 0.996 64 662 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.01 0.93 – 1.1 0.785 611 6208 exclusion phecode
364.1 Corneal opacity Sense Organs 1.16 0.927 – 1.45 0.196 85 874 exclusion phecode
364.2 Corneal edema Sense Organs 0.9 0.706 – 1.15 0.395 72 769 exclusion phecode
364.4 Corneal degenerations Sense Organs 0.964 0.828 – 1.12 0.639 194 1934 exclusion phecode
364.41 Keratoconus Sense Organs 0.932 0.742 – 1.17 0.545 83 837 exclusion phecode
364.5 Corneal dystrophy Sense Organs 1.13 0.974 – 1.31 0.106 195 2029 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 1.22 0.99 – 1.5 0.0623 96 957 exclusion phecode
365 Glaucoma Sense Organs 1.04 1 – 1.07 0.0315 4159 42129 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 1.05 0.986 – 1.13 0.12 967 9860 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 1.06 0.989 – 1.13 0.1 961 9812 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.03 0.946 – 1.11 0.542 664 6679 exclusion phecode
366 Cataract Sense Organs 1.03 1.01 – 1.04 0.00127 18922 161250 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 1.14 0.894 – 1.45 0.289 68 674 exclusion phecode
366.2 Senile cataract Sense Organs 1.04 1.01 – 1.06 0.00307 7791 77972 exclusion phecode
366.3 Traumatic cataract Sense Organs 0.91 0.741 – 1.12 0.368 99 982 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.04 0.992 – 1.08 0.105 2294 23098 exclusion phecode
367.1 Myopia Sense Organs 1.05 0.985 – 1.11 0.139 1196 11982 exclusion phecode
367.2 Astigmatism Sense Organs 1.17 1.01 – 1.36 0.0367 178 1823 exclusion phecode
367.8 Hypermetropia Sense Organs 1.02 0.896 – 1.17 0.741 239 2428 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.03 0.955 – 1.12 0.407 687 6916 exclusion phecode
368 Visual disturbances Sense Organs 1.01 0.974 – 1.05 0.52 2828 28519 exclusion phecode
368.1 Amblyopia Sense Organs 1.09 0.993 – 1.19 0.0704 505 5072 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.98 0.904 – 1.06 0.63 693 7043 exclusion phecode
368.3 Anisometropia Sense Organs 1.1 0.925 – 1.31 0.278 145 1471 exclusion phecode
368.4 Visual field defects Sense Organs 1.11 0.986 – 1.24 0.0855 310 3204 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.992 0.91 – 1.08 0.857 583 5919 exclusion phecode
369 Infection of the eye Sense Organs 1.09 0.994 – 1.19 0.0661 520 5329 exclusion phecode
369.2 Eye infection, viral Sense Organs 1.21 1 – 1.47 0.0449 120 1212 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 1.15 1 – 1.33 0.0481 202 2054 exclusion phecode
370 Keratitis Sense Organs 1 0.884 – 1.13 0.979 277 2756 exclusion phecode
370.1 Corneal ulcer Sense Organs 1.01 0.846 – 1.2 0.927 137 1355 exclusion phecode
371 Inflammation of the eye Sense Organs 0.983 0.945 – 1.02 0.388 2878 29472 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.967 0.878 – 1.07 0.502 455 4667 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 1 0.959 – 1.05 0.925 2219 22759 exclusion phecode
372 Disorders of conjunctiva Sense Organs 0.985 0.91 – 1.07 0.717 709 7273 exclusion phecode
374 Other disorders of eyelids Sense Organs 1.05 1.02 – 1.08 0.000504 5275 54526 exclusion phecode
374.1 Ectropion or entropion Sense Organs 1.09 1.02 – 1.16 0.0105 969 10113 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 1.05 1 – 1.11 0.04 1735 17480 exclusion phecode
375 Disorders of lacrimal system Sense Organs 1.04 0.989 – 1.08 0.135 2054 21068 exclusion phecode
375.2 Epiphora Sense Organs 1.06 0.988 – 1.14 0.102 830 8580 exclusion phecode
376 Disorders of the orbit Sense Organs 1.06 0.843 – 1.34 0.604 80 827 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.02 0.911 – 1.14 0.73 346 3492 exclusion phecode
377.1 Optic atrophy Sense Organs 0.825 0.613 – 1.11 0.204 52 552 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.927 0.764 – 1.12 0.438 121 1223 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.05 0.997 – 1.11 0.0653 1357 13602 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.06 0.993 – 1.14 0.0801 886 8771 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.919 0.791 – 1.07 0.266 199 2049 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.11 0.976 – 1.26 0.112 264 2653 exclusion phecode
379 Other disorders of eye Sense Organs 1.04 1 – 1.07 0.0501 3540 35372 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 1.01 0.955 – 1.07 0.672 1320 13065 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.08 1.03 – 1.14 0.00218 1723 17246 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 0.888 0.682 – 1.16 0.376 69 684 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.973 0.873 – 1.08 0.619 377 3854 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.04 0.881 – 1.22 0.658 159 1625 exclusion phecode
380 Disorders of external ear Sense Organs 0.98 0.899 – 1.07 0.655 582 6151 exclusion phecode
380.1 Otitis externa Sense Organs 1.05 0.956 – 1.15 0.314 485 4934 exclusion phecode
380.4 Impacted cerumen Sense Organs 0.992 0.887 – 1.11 0.889 344 3481 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.01 0.964 – 1.06 0.689 2068 20749 exclusion phecode
381.1 Otitis media Sense Organs 1.01 0.965 – 1.07 0.573 1695 17048 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.03 0.959 – 1.11 0.419 820 8228 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.887 0.758 – 1.04 0.135 189 1867 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.993 0.842 – 1.17 0.931 168 1645 exclusion phecode
381.9 Otorrhea Sense Organs 1.02 0.901 – 1.16 0.737 273 2699 exclusion phecode
382 Otalgia Sense Organs 0.924 0.818 – 1.04 0.202 298 2975 exclusion phecode
383 Otosclerosis Sense Organs 1.07 0.951 – 1.2 0.262 298 2987 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 0.983 0.928 – 1.04 0.573 1260 12571 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 0.997 0.935 – 1.06 0.921 1008 10083 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.07 0.989 – 1.15 0.0958 762 7551 exclusion phecode
385.3 Cholesteatoma Sense Organs 1.11 1.02 – 1.21 0.0114 594 5849 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.02 0.89 – 1.17 0.789 233 2316 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.04 0.992 – 1.1 0.103 1666 16709 exclusion phecode
386.1 Meniere's disease Sense Organs 1.11 1.02 – 1.21 0.0183 552 5542 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.953 0.854 – 1.06 0.385 360 3616 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.03 0.954 – 1.11 0.455 734 7384 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.06 1.03 – 1.1 9.63e-05 4379 44026 exclusion phecode
388 Other disorders of ear Sense Organs 1.14 0.987 – 1.32 0.0754 197 1940 exclusion phecode
389 Hearing loss Sense Organs 1.05 1.01 – 1.08 0.00775 3973 40174 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.985 0.892 – 1.09 0.763 437 4365 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.11 1 – 1.22 0.0457 433 4344 exclusion phecode
389.4 Tinnitus Sense Organs 0.989 0.901 – 1.09 0.817 491 4915 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.01 0.975 – 1.04 0.744 4639 46782 exclusion phecode
394.2 Mitral valve disease Circulatory System 0.99 0.952 – 1.03 0.625 2844 28599 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.03 0.966 – 1.09 0.403 1193 12237 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.02 0.953 – 1.09 0.595 1003 10088 exclusion phecode
395 Heart valve disorders Circulatory System 0.987 0.954 – 1.02 0.427 3988 40328 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.983 0.944 – 1.02 0.405 2744 27611 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.951 0.837 – 1.08 0.435 263 2619 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.24 1.03 – 1.5 0.0244 101 1001 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.906 0.725 – 1.13 0.389 89 932 exclusion phecode
395.6 Heart valve replaced Circulatory System 1 0.947 – 1.06 0.937 1383 14271 exclusion phecode
396 Abnormal heart sounds Circulatory System 0.924 0.863 – 0.989 0.023 997 10073 exclusion phecode
401 Hypertension Circulatory System 1.01 1 – 1.02 0.0185 69829 259278 exclusion phecode
401.1 Essential hypertension Circulatory System 1.01 1 – 1.02 0.0193 69621 259061 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.03 0.983 – 1.09 0.198 1742 18224 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 0.991 0.887 – 1.11 0.872 360 3548 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.04 0.986 – 1.1 0.142 1397 14831 exclusion phecode
401.3 Other hypertensive complications Circulatory System 0.998 0.828 – 1.2 0.986 123 1384 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 0.995 0.941 – 1.05 0.859 1397 14293 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.01 1 – 1.03 0.0237 29750 202569 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.04 1.01 – 1.07 0.00675 4873 49085 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.02 0.996 – 1.04 0.114 11419 107742 exclusion phecode
411.3 Angina pectoris Circulatory System 1.03 1.01 – 1.05 0.000369 15093 137453 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.02 1 – 1.03 0.0264 19239 148218 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.949 0.874 – 1.03 0.218 668 6672 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.02 1 – 1.04 0.0345 14389 125969 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1 0.942 – 1.07 0.941 1162 11645 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 0.982 0.934 – 1.03 0.486 1727 17405 exclusion phecode
414.2 ASCVD Circulatory System 0.857 0.653 – 1.13 0.266 69 687 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.01 0.983 – 1.05 0.367 4250 42895 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.03 0.806 – 1.31 0.832 68 718 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.04 0.956 – 1.14 0.348 573 5727 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.06 0.962 – 1.18 0.228 425 4267 exclusion phecode
416 Cardiomegaly Circulatory System 1.04 0.998 – 1.08 0.0643 2552 25564 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.02 1.01 – 1.03 0.00245 27395 260560 exclusion phecode
418.1 Precordial pain Circulatory System 1.05 1.01 – 1.09 0.0083 3429 34246 exclusion phecode
420 Carditis Circulatory System 1.02 0.974 – 1.07 0.39 2018 20168 exclusion phecode
420.1 Myocarditis Circulatory System 0.866 0.711 – 1.05 0.152 117 1202 exclusion phecode
420.2 Pericarditis Circulatory System 1.03 0.972 – 1.09 0.325 1282 12846 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.1 0.959 – 1.27 0.169 216 2137 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.11 0.916 – 1.34 0.287 108 1079 exclusion phecode
420.3 Endocarditis Circulatory System 1.03 0.948 – 1.11 0.522 689 6872 exclusion phecode
425 Cardiomyopathy Circulatory System 0.99 0.932 – 1.05 0.736 1219 12164 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.99 0.931 – 1.05 0.747 1185 11824 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.01 0.847 – 1.21 0.897 131 1276 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.89 0.752 – 1.05 0.175 159 1562 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.01 0.775 – 1.32 0.938 59 583 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.03 1.01 – 1.06 0.0127 6543 65983 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.01 0.965 – 1.06 0.634 1994 20151 exclusion phecode
426.21 First degree AV block Circulatory System 1 0.939 – 1.08 0.891 932 9399 exclusion phecode
426.23 Second degree AV block Circulatory System 1.04 0.941 – 1.15 0.433 425 4323 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 0.996 0.911 – 1.09 0.921 558 5599 exclusion phecode
426.25 Other heart block Circulatory System 0.909 0.75 – 1.1 0.328 126 1263 exclusion phecode
426.3 Bundle branch block Circulatory System 1.03 0.996 – 1.07 0.0843 3171 31812 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.07 1.01 – 1.13 0.0257 1413 14293 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.01 0.964 – 1.07 0.579 1671 16671 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.994 0.866 – 1.14 0.932 227 2250 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.15 0.885 – 1.5 0.296 54 568 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.04 0.999 – 1.09 0.0557 2308 23571 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.04 0.991 – 1.08 0.121 2123 21653 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.01 0.995 – 1.02 0.221 22905 198010 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 0.986 0.949 – 1.02 0.463 3035 30731 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.98 0.938 – 1.02 0.379 2220 22570 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.03 0.961 – 1.1 0.408 890 8918 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.01 0.988 – 1.02 0.514 13783 127510 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1 0.966 – 1.04 0.866 3047 30885 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.05 0.99 – 1.12 0.0995 1146 11374 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.02 0.909 – 1.14 0.761 328 3276 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.04 0.971 – 1.11 0.275 955 9443 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.978 0.912 – 1.05 0.547 887 9131 exclusion phecode
427.6 Premature beats Circulatory System 1.05 0.956 – 1.15 0.315 509 5157 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 0.996 0.814 – 1.22 0.971 112 1125 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.03 0.987 – 1.08 0.159 2082 21031 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.01 0.91 – 1.12 0.827 379 3828 exclusion phecode
427.9 Palpitations Circulatory System 1.03 0.991 – 1.06 0.153 3652 36763 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.02 0.988 – 1.05 0.258 5312 53328 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.03 0.982 – 1.08 0.236 2009 20064 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.01 0.98 – 1.04 0.463 4217 42379 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.03 0.952 – 1.11 0.466 693 6903 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.02 0.774 – 1.33 0.911 53 607 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.03 0.941 – 1.13 0.505 508 5010 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.02 0.879 – 1.18 0.817 187 1905 exclusion phecode
430 Intracranial hemorrhage Circulatory System 0.994 0.946 – 1.04 0.813 1793 18093 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.01 0.937 – 1.09 0.817 807 8088 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.01 0.935 – 1.09 0.787 717 7317 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 0.854 0.744 – 0.98 0.0249 256 2543 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.02 0.997 – 1.04 0.0839 8321 83473 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.07 1.01 – 1.14 0.0259 1132 11251 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.13 0.986 – 1.3 0.0786 213 2158 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.04 1 – 1.07 0.0278 4026 40341 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.03 0.979 – 1.09 0.246 1592 16031 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1 0.963 – 1.04 0.924 2739 27601 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.02 0.973 – 1.07 0.427 2024 20377 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.03 0.922 – 1.14 0.645 382 3800 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.03 0.967 – 1.09 0.382 1215 12206 exclusion phecode
440 Atherosclerosis Circulatory System 0.997 0.941 – 1.06 0.929 1296 13097 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.969 0.789 – 1.19 0.762 99 1066 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.967 0.896 – 1.04 0.392 760 7662 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 0.969 0.851 – 1.1 0.633 268 2724 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.09 1 – 1.19 0.0411 578 5891 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.97 0.854 – 1.1 0.643 266 2701 exclusion phecode
442 Other aneurysm Circulatory System 1.01 0.962 – 1.06 0.675 1784 18045 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.01 0.952 – 1.07 0.804 1369 13859 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.01 0.943 – 1.09 0.737 874 8792 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.01 0.823 – 1.25 0.896 93 968 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.13 0.964 – 1.32 0.132 162 1620 exclusion phecode
442.4 Arterial dissection Circulatory System 1.24 0.939 – 1.63 0.131 52 536 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 0.946 0.815 – 1.1 0.469 193 1953 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.04 1 – 1.07 0.0389 3734 37547 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.04 0.974 – 1.1 0.256 1083 11045 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.946 0.848 – 1.05 0.312 366 3712 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.04 1.01 – 1.08 0.0157 3510 35273 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.05 1.01 – 1.1 0.0179 2464 24573 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.07 0.994 – 1.14 0.0726 876 8807 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.07 0.979 – 1.17 0.133 525 5285 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.976 0.905 – 1.05 0.538 771 7877 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.9 0.764 – 1.06 0.21 168 1817 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.01 0.902 – 1.12 0.913 367 3700 exclusion phecode
446.9 Arteritis NOS Circulatory System 0.987 0.86 – 1.13 0.856 227 2299 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.02 0.959 – 1.08 0.586 1272 12704 exclusion phecode
447.1 Stricture of artery Circulatory System 1.04 0.972 – 1.12 0.24 826 8302 exclusion phecode
448 Disease of capillaries Circulatory System 1.13 0.949 – 1.36 0.167 132 1366 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.981 0.903 – 1.07 0.657 649 6770 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.02 0.982 – 1.05 0.375 3748 38112 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.02 0.98 – 1.05 0.397 3487 35516 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 0.98 0.894 – 1.07 0.658 532 5415 exclusion phecode
454 Varicose veins Circulatory System 0.997 0.977 – 1.02 0.75 10719 108234 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 0.994 0.975 – 1.01 0.546 11037 111288 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.968 0.887 – 1.06 0.47 569 6060 exclusion phecode
455 Hemorrhoids Circulatory System 1.02 1 – 1.03 0.0101 22449 226271 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.933 0.794 – 1.1 0.402 169 1785 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.953 0.777 – 1.17 0.647 95 920 exclusion phecode
458 Hypotension Circulatory System 1.01 0.986 – 1.04 0.312 5482 55318 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.02 0.962 – 1.08 0.514 1276 12738 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.16 1.01 – 1.33 0.0304 220 2218 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.01 0.975 – 1.05 0.571 3319 33577 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.02 1.01 – 1.04 0.00934 15353 154149 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 0.994 0.832 – 1.19 0.946 132 1358 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.02 1.01 – 1.04 0.00643 15202 152830 exclusion phecode
464 Acute sinusitis Respiratory 0.989 0.85 – 1.15 0.891 189 1890 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.02 0.976 – 1.07 0.374 2176 22053 exclusion phecode
465.2 Acute pharyngitis Respiratory 0.964 0.895 – 1.04 0.333 795 8069 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.08 0.919 – 1.28 0.339 158 1584 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.02 0.991 – 1.05 0.16 4504 45103 exclusion phecode
471 Nasal polyps Respiratory 1.09 1.05 – 1.13 9.57e-06 3159 31723 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.13 1.06 – 1.21 0.000328 923 9268 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.04 0.999 – 1.09 0.0567 2434 24519 exclusion phecode
473.1 Chronic laryngitis Respiratory 0.946 0.768 – 1.16 0.601 99 993 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.08 0.953 – 1.23 0.224 253 2525 exclusion phecode
473.4 Voice disturbance Respiratory 1.1 1.04 – 1.18 0.00244 1034 10320 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 0.981 0.933 – 1.03 0.465 1716 17308 exclusion phecode
474.1 Acute tonsillitis Respiratory 0.997 0.911 – 1.09 0.945 532 5373 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.981 0.921 – 1.04 0.553 1090 10935 exclusion phecode
475 Chronic sinusitis Respiratory 1.03 0.989 – 1.07 0.155 2493 25021 exclusion phecode
476 Allergic rhinitis Respiratory 0.988 0.925 – 1.06 0.726 1003 10254 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 0.982 0.94 – 1.03 0.409 2334 23396 exclusion phecode
478 Throat pain Respiratory 1.06 0.945 – 1.18 0.337 362 3663 exclusion phecode
479 Other upper respiratory disease Respiratory 1.04 1 – 1.07 0.0262 3900 39330 exclusion phecode
480 Pneumonia Respiratory 1.02 1 – 1.04 0.0439 9834 98981 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.02 0.997 – 1.05 0.0868 6307 63592 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.03 1 – 1.06 0.0532 5597 56341 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.07 0.861 – 1.34 0.53 88 893 exclusion phecode
480.2 Viral pneumonia Respiratory 1.15 0.894 – 1.47 0.278 66 701 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.954 0.771 – 1.18 0.664 92 947 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.951 0.881 – 1.03 0.201 750 7582 exclusion phecode
481 Influenza Respiratory 1 0.892 – 1.12 0.976 310 3173 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.11 0.96 – 1.29 0.157 186 1857 exclusion phecode
495 Asthma Respiratory 1.01 1 – 1.03 0.0299 24617 241883 exclusion phecode
495.2 Asthma with exacerbation Respiratory 0.939 0.82 – 1.08 0.363 236 2431 exclusion phecode
496 Chronic airway obstruction Respiratory 1.04 1.02 – 1.06 0.000563 9919 97070 exclusion phecode
496.1 Emphysema Respiratory 1.03 0.981 – 1.09 0.221 1662 16623 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.03 0.991 – 1.07 0.132 2832 28138 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.03 0.989 – 1.07 0.159 2600 25831 exclusion phecode
496.3 Bronchiectasis Respiratory 1.03 0.98 – 1.08 0.244 1763 18002 exclusion phecode
497 Bronchitis Respiratory 0.976 0.895 – 1.06 0.571 596 6022 exclusion phecode
500 Lung disease due to external agents Respiratory 1.07 0.964 – 1.19 0.205 386 3860 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.09 0.856 – 1.38 0.491 74 749 exclusion phecode
500.2 Pneumoconiosis Respiratory 1.07 0.938 – 1.23 0.3 223 2259 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.09 1.01 – 1.18 0.0344 625 6236 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.01 0.937 – 1.08 0.867 868 8742 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.04 0.947 – 1.14 0.418 484 4867 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.03 0.915 – 1.15 0.645 313 3131 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 0.857 0.642 – 1.14 0.293 58 581 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.01 0.947 – 1.07 0.792 1085 10893 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.02 0.994 – 1.05 0.123 6085 61409 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.02 0.969 – 1.07 0.514 1904 19117 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.04 0.994 – 1.08 0.0963 2486 24802 exclusion phecode
509.1 Respiratory failure Respiratory 1.04 0.995 – 1.09 0.0837 1976 19714 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.04 0.986 – 1.09 0.158 1732 17239 exclusion phecode
509.5 Respiratory arrest Respiratory 0.995 0.84 – 1.18 0.95 138 1376 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.09 0.981 – 1.22 0.107 370 3672 exclusion phecode
510 Other diseases of lung Respiratory 1.06 0.982 – 1.15 0.132 718 7230 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.04 1.01 – 1.06 0.00178 8621 86785 exclusion phecode
512.1 Wheezing Respiratory 1.03 0.894 – 1.18 0.709 208 2100 exclusion phecode
512.2 Painful respiration Respiratory 0.974 0.843 – 1.12 0.716 200 1995 exclusion phecode
512.7 Shortness of breath Respiratory 1.04 1.01 – 1.07 0.00277 5593 56163 exclusion phecode
512.8 Cough Respiratory 1.03 0.994 – 1.08 0.0915 2716 27537 exclusion phecode
512.9 Other dyspnea Respiratory 1.05 0.977 – 1.12 0.197 874 8767 exclusion phecode
513 Respiratory abnormalities Respiratory 1.05 0.967 – 1.15 0.231 586 5833 exclusion phecode
513.3 Hypoventilation Respiratory 0.946 0.744 – 1.2 0.651 78 793 exclusion phecode
513.4 Hyperventilation Respiratory 0.971 0.854 – 1.1 0.657 269 2673 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.04 0.874 – 1.23 0.679 146 1458 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.03 0.99 – 1.08 0.136 2338 23613 exclusion phecode
516 Abnormal sputum Respiratory 0.988 0.943 – 1.03 0.601 2018 20452 exclusion phecode
516.1 Hemoptysis Respiratory 1.01 0.959 – 1.05 0.829 1963 19889 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.03 1.01 – 1.05 0.00481 8889 89900 exclusion phecode
519.2 Respiratory complications Respiratory 1.01 0.898 – 1.13 0.897 310 3127 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.03 1.01 – 1.06 0.00498 8410 84975 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.981 0.869 – 1.11 0.759 284 2921 exclusion phecode
520 Disorders of tooth development Digestive 1.01 0.965 – 1.06 0.622 1983 19810 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.906 0.667 – 1.23 0.525 51 519 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 1.03 0.991 – 1.08 0.123 2298 22943 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 0.996 0.958 – 1.04 0.855 2905 29257 exclusion phecode
521.1 Dental caries Digestive 1 0.963 – 1.04 0.961 2915 29384 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 0.945 0.898 – 0.994 0.0286 1722 17180 exclusion phecode
522.5 Periapical abscess Digestive 0.938 0.881 – 0.998 0.0445 1136 11343 exclusion phecode
523 Gingival and periodontal diseases Digestive 0.986 0.937 – 1.04 0.596 1634 16280 exclusion phecode
523.1 Gingivitis Digestive 1.02 0.837 – 1.25 0.825 107 1085 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1 0.944 – 1.07 0.9 1138 11326 exclusion phecode
523.31 Acute periodontitis Digestive 1.06 0.979 – 1.15 0.148 655 6485 exclusion phecode
523.32 Chronic periodontitis Digestive 0.934 0.855 – 1.02 0.131 543 5416 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.06 0.944 – 1.19 0.32 318 3226 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.05 0.927 – 1.18 0.455 295 2975 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.998 0.957 – 1.04 0.906 2586 25791 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.805 0.62 – 1.05 0.103 72 687 exclusion phecode
526 Diseases of the jaws Digestive 0.978 0.912 – 1.05 0.54 891 8998 exclusion phecode
526.1 Cysts of the jaws Digestive 0.981 0.873 – 1.1 0.743 319 3180 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.829 0.642 – 1.07 0.152 61 601 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.08 0.946 – 1.23 0.261 229 2342 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.07 0.934 – 1.22 0.345 222 2275 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.878 0.712 – 1.08 0.223 107 1057 exclusion phecode
526.9 Jaw disease NOS Digestive 0.948 0.823 – 1.09 0.463 219 2248 exclusion phecode
527 Diseases of the salivary glands Digestive 0.962 0.887 – 1.04 0.354 665 6684 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 0.834 0.656 – 1.06 0.138 81 804 exclusion phecode
527.2 Sialoadenitis Digestive 0.971 0.87 – 1.09 0.607 351 3517 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.11 0.846 – 1.46 0.452 58 596 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 0.996 0.824 – 1.2 0.969 115 1159 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.02 0.985 – 1.06 0.264 3656 37365 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.15 1.04 – 1.26 0.00493 440 4508 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.17 1.05 – 1.29 0.00411 367 3756 exclusion phecode
528.12 Oral aphthae Digestive 0.993 0.783 – 1.26 0.952 78 800 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.915 0.778 – 1.08 0.284 176 1722 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.919 0.756 – 1.12 0.399 120 1173 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.9 0.719 – 1.13 0.356 92 909 exclusion phecode
528.5 Diseases of lips Digestive 1.06 0.971 – 1.15 0.207 614 6558 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1 0.889 – 1.13 0.972 293 2971 exclusion phecode
528.7 Sialolithiasis Digestive 1.08 0.958 – 1.21 0.214 303 3034 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 0.985 0.927 – 1.05 0.623 1170 11838 exclusion phecode
529.1 Glossitis Digestive 0.951 0.842 – 1.08 0.424 285 2872 exclusion phecode
530 Diseases of esophagus Digestive 1.02 1.01 – 1.03 0.000183 32040 269532 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.02 1.01 – 1.04 9.53e-05 29954 262896 exclusion phecode
530.11 GERD Digestive 1.02 1 – 1.03 0.0158 21699 217582 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.05 1.02 – 1.08 0.0014 4995 49866 exclusion phecode
530.14 Reflux esophagitis Digestive 1.01 0.994 – 1.04 0.166 10044 100616 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.06 1 – 1.11 0.0415 1608 16163 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 0.987 0.939 – 1.04 0.596 1786 17875 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1 0.92 – 1.09 0.959 601 6138 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.13 0.959 – 1.33 0.145 145 1452 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.03 0.914 – 1.15 0.663 326 3305 exclusion phecode
530.9 Heartburn Digestive 1.06 1.01 – 1.11 0.0107 1997 20131 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.02 0.991 – 1.04 0.222 6779 68117 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.03 0.946 – 1.12 0.513 615 6090 exclusion phecode
531.2 Gastric ulcer Digestive 1.01 0.979 – 1.05 0.482 3903 39233 exclusion phecode
531.3 Duodenal ulcer Digestive 1.01 0.969 – 1.05 0.707 2863 28826 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.16 1.05 – 1.28 0.00267 401 4112 exclusion phecode
532 Dysphagia Digestive 1.04 1.01 – 1.07 0.00411 6131 61937 exclusion phecode
535 Gastritis and duodenitis Digestive 1.03 1.02 – 1.05 3.85e-07 26896 252042 exclusion phecode
535.1 Acute gastritis Digestive 1.01 0.949 – 1.07 0.794 1128 11387 exclusion phecode
535.2 Atrophic gastritis Digestive 1.06 0.955 – 1.19 0.257 359 3542 exclusion phecode
535.6 Duodenitis Digestive 1.02 0.997 – 1.05 0.0886 7288 72951 exclusion phecode
535.8 Other specified gastritis Digestive 1.03 1.01 – 1.05 0.0124 7720 77589 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.09 0.915 – 1.31 0.329 115 1143 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.1 0.97 – 1.24 0.142 253 2478 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.04 1.01 – 1.08 0.024 3255 32549 exclusion phecode
540 Appendiceal conditions Digestive 0.975 0.938 – 1.01 0.189 2991 30042 exclusion phecode
540.1 Appendicitis Digestive 0.971 0.934 – 1.01 0.147 2806 28166 exclusion phecode
540.11 Acute appendicitis Digestive 0.974 0.934 – 1.01 0.209 2522 25319 exclusion phecode
550 Abdominal hernia Digestive 1.02 1.01 – 1.03 0.000106 43384 273235 exclusion phecode
550.1 Inguinal hernia Digestive 1.01 0.997 – 1.03 0.108 15004 118484 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.03 1.02 – 1.05 3.44e-07 25386 230230 exclusion phecode
550.3 Femoral hernia Digestive 0.987 0.909 – 1.07 0.765 630 6283 exclusion phecode
550.4 Umbilical hernia Digestive 1.01 0.971 – 1.04 0.745 3552 35769 exclusion phecode
550.5 Ventral hernia Digestive 1.04 1 – 1.08 0.032 3256 33020 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1 0.973 – 1.04 0.768 4229 42934 exclusion phecode
555.1 Regional enteritis Digestive 0.979 0.93 – 1.03 0.426 1647 16761 exclusion phecode
555.2 Ulcerative colitis Digestive 1.01 0.976 – 1.05 0.478 3029 30694 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 0.975 0.888 – 1.07 0.591 507 5178 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.08 1.01 – 1.15 0.0206 1001 10216 exclusion phecode
556.1 Ulceration of intestine Digestive 1.06 0.977 – 1.15 0.162 636 6488 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.96 0.849 – 1.09 0.513 289 2897 exclusion phecode
557.1 Celiac disease Digestive 0.995 0.947 – 1.05 0.846 1754 17742 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.03 1.02 – 1.05 0.000112 14851 149700 exclusion phecode
559 Ileostomy status Digestive 1.01 0.956 – 1.06 0.785 1568 15861 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.03 0.991 – 1.06 0.151 3750 37828 exclusion phecode
560.1 Paralytic ileus Digestive 1.06 0.965 – 1.16 0.225 484 4994 exclusion phecode
560.2 Impaction of intestine Digestive 0.973 0.855 – 1.11 0.683 259 2567 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.05 0.972 – 1.12 0.232 793 8013 exclusion phecode
560.4 Other intestinal obstruction Digestive 1.03 0.989 – 1.06 0.165 3211 32274 exclusion phecode
561 Symptoms involving digestive system Digestive 1.01 0.991 – 1.03 0.338 15118 152208 exclusion phecode
561.1 Diarrhea Digestive 1.02 0.928 – 1.12 0.668 449 4470 exclusion phecode
561.2 Flatulence Digestive 1.03 0.981 – 1.09 0.223 1618 16266 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1.02 1 – 1.03 0.0125 25439 203884 exclusion phecode
562.1 Diverticulosis Digestive 1.02 1 – 1.03 0.0123 25400 203835 exclusion phecode
563 Constipation Digestive 1 0.984 – 1.03 0.674 9865 99351 exclusion phecode
564 Functional digestive disorders Digestive 1.01 0.999 – 1.03 0.0641 20687 202414 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.02 0.992 – 1.05 0.161 5332 53392 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 0.972 0.921 – 1.03 0.292 1559 15862 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.02 1.01 – 1.04 0.0101 14472 145762 exclusion phecode
565 Anal and rectal conditions Digestive 1.01 0.99 – 1.03 0.391 14068 142130 exclusion phecode
565.1 Anal and rectal polyp Digestive 1.01 0.981 – 1.03 0.668 6985 70625 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 0.992 0.924 – 1.06 0.825 887 8971 exclusion phecode
568 Other disorders of peritoneum Digestive 1.03 0.988 – 1.06 0.191 3134 31437 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.02 0.984 – 1.06 0.264 2985 29893 exclusion phecode
569 Other disorders of intestine Digestive 1.01 0.978 – 1.04 0.517 3991 40321 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.05 0.877 – 1.26 0.601 138 1405 exclusion phecode
569.2 Gastrointestinal complications Digestive 0.97 0.88 – 1.07 0.541 463 4668 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.07 1.03 – 1.11 0.00062 2806 28512 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.04 0.983 – 1.09 0.189 1607 16315 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.814 0.664 – 0.998 0.0482 105 1102 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.21 1.06 – 1.38 0.00386 242 2459 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.1 1.02 – 1.17 0.00763 932 9410 exclusion phecode
571.81 Portal hypertension Digestive 1.12 1.02 – 1.22 0.0165 498 5090 exclusion phecode
572 Ascites (non malignant) Digestive 1.03 0.972 – 1.08 0.359 1463 14835 exclusion phecode
573 Other disorders of liver Digestive 1.03 0.972 – 1.08 0.348 1418 14347 exclusion phecode
573.2 Liver replaced by transplant Digestive 0.974 0.765 – 1.24 0.833 72 924 exclusion phecode
573.3 Hepatomegaly Digestive 1.05 0.926 – 1.18 0.461 284 2836 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.05 0.982 – 1.13 0.144 859 8589 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.05 1.01 – 1.09 0.00624 3288 33291 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.21 1.05 – 1.39 0.00912 198 1991 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.02 1 – 1.04 0.0119 14992 150485 exclusion phecode
574.1 Cholelithiasis Digestive 1.02 1 – 1.04 0.0238 13007 130657 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.04 0.983 – 1.1 0.182 1441 14523 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.01 0.985 – 1.04 0.358 5208 52363 exclusion phecode
574.2 Calculus of bile duct Digestive 1.02 0.977 – 1.06 0.402 2524 25210 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.04 0.996 – 1.08 0.0817 2652 26482 exclusion phecode
575 Other biliary tract disease Digestive 1.04 1 – 1.07 0.0396 3701 37251 exclusion phecode
575.1 Cholangitis Digestive 1.01 0.915 – 1.11 0.902 472 4722 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.01 0.939 – 1.1 0.717 741 7436 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 1.05 0.953 – 1.16 0.319 442 4405 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.06 1 – 1.12 0.0337 1352 13624 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.06 0.997 – 1.14 0.0606 991 9974 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.871 0.774 – 0.98 0.0218 329 3325 exclusion phecode
577 Diseases of pancreas Digestive 1.05 1.01 – 1.1 0.0121 2553 25631 exclusion phecode
577.1 Acute pancreatitis Digestive 1.06 1.01 – 1.11 0.011 1911 19199 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.05 0.954 – 1.15 0.335 501 4968 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.996 0.891 – 1.11 0.937 346 3489 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.02 1.01 – 1.04 0.00372 19734 198962 exclusion phecode
578.1 Hematemesis Digestive 1.03 0.981 – 1.08 0.25 1885 18839 exclusion phecode
578.2 Blood in stool Digestive 1.03 0.993 – 1.08 0.11 2507 25232 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.03 1.01 – 1.05 0.000547 12489 126197 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.01 0.981 – 1.04 0.495 5065 50949 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.04 0.986 – 1.1 0.143 1468 14937 exclusion phecode
579.2 Splenomegaly Digestive 1.06 0.956 – 1.18 0.258 388 4073 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.03 0.98 – 1.09 0.234 1580 15919 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.02 0.965 – 1.08 0.49 1420 14682 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.01 0.941 – 1.08 0.855 972 10067 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.99 0.776 – 1.26 0.933 68 704 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.992 0.822 – 1.2 0.932 123 1310 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1 0.932 – 1.08 0.944 811 8345 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.05 0.953 – 1.16 0.324 447 4504 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.01 0.884 – 1.16 0.841 224 2364 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.04 0.907 – 1.19 0.582 230 2431 exclusion phecode
585 Renal failure Genitourinary 1.01 0.982 – 1.03 0.551 6526 66593 exclusion phecode
585.1 Acute renal failure Genitourinary 0.998 0.967 – 1.03 0.902 4284 43229 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.02 0.964 – 1.08 0.502 1365 14015 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.01 0.963 – 1.05 0.814 2423 25260 exclusion phecode
585.31 Renal dialysis Genitourinary 1.02 0.923 – 1.12 0.713 432 4769 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1 0.967 – 1.04 0.831 3153 32193 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.02 0.883 – 1.19 0.75 191 2002 exclusion phecode
586.11 Small kidney Genitourinary 1.03 0.873 – 1.21 0.754 163 1728 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 0.978 0.92 – 1.04 0.473 1187 12036 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.973 0.762 – 1.24 0.826 74 759 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.996 0.928 – 1.07 0.919 858 8784 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.04 0.924 – 1.17 0.524 290 3574 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.08 0.878 – 1.33 0.464 91 944 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 0.953 0.778 – 1.17 0.645 106 1108 exclusion phecode
590 Pyelonephritis Genitourinary 1.01 0.956 – 1.07 0.663 1271 12844 exclusion phecode
591 Urinary tract infection Genitourinary 1.01 0.989 – 1.03 0.38 11818 119050 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.04 1 – 1.08 0.0461 2814 28474 exclusion phecode
592.1 Cystitis Genitourinary 1.04 1 – 1.08 0.0512 2755 27866 exclusion phecode
592.11 Acute cystitis Genitourinary 1.03 0.864 – 1.23 0.728 127 1335 exclusion phecode
592.12 Chronic cystitis Genitourinary 1.02 0.952 – 1.1 0.549 836 8534 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.08 0.948 – 1.23 0.249 241 2417 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.963 0.818 – 1.13 0.652 158 1596 exclusion phecode
593 Hematuria Genitourinary 1.01 0.997 – 1.03 0.119 15289 153863 exclusion phecode
594 Urinary calculus Genitourinary 1.02 0.995 – 1.05 0.12 6101 61384 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.03 0.988 – 1.06 0.19 3031 30499 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.05 0.973 – 1.13 0.206 726 7412 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.02 0.973 – 1.06 0.477 2301 23133 exclusion phecode
594.8 Renal colic Genitourinary 1.01 0.965 – 1.06 0.652 1974 19769 exclusion phecode
595 Hydronephrosis Genitourinary 0.978 0.931 – 1.03 0.367 1845 18662 exclusion phecode
596 Other disorders of bladder Genitourinary 1.02 0.996 – 1.04 0.107 9306 93463 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.03 0.983 – 1.08 0.204 1860 18725 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1.04 0.992 – 1.1 0.0986 1588 15943 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1 0.97 – 1.04 0.846 3748 37576 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.01 0.97 – 1.04 0.745 3178 31772 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.07 0.84 – 1.35 0.603 77 756 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.02 0.987 – 1.06 0.212 3382 33819 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.04 0.918 – 1.17 0.568 290 2891 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.995 – 1.03 0.184 17634 177282 exclusion phecode
599.1 Urinary obstruction Genitourinary 1.01 0.851 – 1.19 0.949 156 1599 exclusion phecode
599.2 Retention of urine Genitourinary 1.01 0.987 – 1.04 0.325 6357 64017 exclusion phecode
599.3 Dysuria Genitourinary 1.06 0.993 – 1.12 0.0804 1151 11522 exclusion phecode
599.4 Urinary incontinence Genitourinary 1.01 0.984 – 1.03 0.591 8412 84411 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.01 0.98 – 1.05 0.421 3818 38513 exclusion phecode
599.6 Oliguria and anuria Genitourinary 0.993 0.807 – 1.22 0.945 94 1001 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.02 0.787 – 1.33 0.858 58 599 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1.05 0.996 – 1.1 0.0714 1827 18321 exclusion phecode
600 Hyperplasia of prostate Genitourinary 1 0.982 – 1.02 0.814 10412 83841 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 0.986 0.94 – 1.03 0.555 1962 19882 exclusion phecode
601.1 Prostatitis Genitourinary 1.01 0.956 – 1.07 0.718 1466 14909 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.956 0.829 – 1.1 0.543 216 2261 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1.03 0.964 – 1.11 0.345 851 8659 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 1.19 0.929 – 1.53 0.167 58 570 exclusion phecode
601.4 Balanoposthitis Genitourinary 0.899 0.79 – 1.02 0.105 277 2741 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.978 0.864 – 1.11 0.73 287 2895 exclusion phecode
602 Other disorders of prostate Genitourinary 0.949 0.894 – 1.01 0.0868 1263 12737 exclusion phecode
603 Other disorders of testis Genitourinary 1.01 0.966 – 1.06 0.612 2036 20681 exclusion phecode
603.1 Hydrocele Genitourinary 1 0.943 – 1.06 1 1260 12810 exclusion phecode
604 Disorders of penis Genitourinary 1 0.968 – 1.04 0.808 3167 31593 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.999 0.96 – 1.04 0.976 2632 26180 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 1.06 0.936 – 1.21 0.347 263 2671 exclusion phecode
608 Other disorders of male genital organs Genitourinary 1.01 0.974 – 1.06 0.485 2695 27102 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.955 0.815 – 1.12 0.564 192 2034 exclusion phecode
609.1 Infertility, male Genitourinary 0.942 0.732 – 1.21 0.64 60 616 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.968 0.806 – 1.16 0.731 149 1592 exclusion phecode
610 Benign mammary dysplasias Genitourinary 1.01 0.964 – 1.05 0.795 2392 24125 exclusion phecode
610.1 Cystic mastopathy Genitourinary 1.1 1.03 – 1.18 0.00612 888 8970 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1.01 0.898 – 1.14 0.824 287 2967 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 0.973 0.856 – 1.11 0.678 289 2922 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.993 0.938 – 1.05 0.812 1350 13484 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.04 0.955 – 1.12 0.4 663 6751 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.996 0.944 – 1.05 0.873 1509 15242 exclusion phecode
611.1 Abnormal mammogram Genitourinary 1 0.763 – 1.32 0.977 55 559 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.992 0.94 – 1.05 0.787 1458 14734 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.953 0.887 – 1.02 0.181 857 8625 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.967 0.899 – 1.04 0.357 824 8245 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 0.821 0.635 – 1.06 0.133 67 705 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 1.05 0.999 – 1.11 0.0533 1584 16022 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.08 1 – 1.17 0.0506 692 6995 exclusion phecode
613.5 Mastodynia Genitourinary 1 0.791 – 1.27 0.979 73 745 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 1.1 1.02 – 1.19 0.0123 680 6804 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1.09 0.971 – 1.23 0.143 316 3194 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.03 1.01 – 1.06 0.0183 5525 55624 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.05 1.01 – 1.1 0.014 2462 24769 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.999 0.929 – 1.08 0.985 806 8105 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.985 0.761 – 1.27 0.907 61 593 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.03 0.93 – 1.14 0.572 409 4117 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.04 0.933 – 1.17 0.461 344 3424 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.993 0.87 – 1.13 0.921 267 2713 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.04 0.994 – 1.08 0.0926 2509 25269 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.06 0.997 – 1.12 0.0622 1276 12802 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.993 0.897 – 1.1 0.887 410 4147 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.01 0.933 – 1.09 0.864 733 7382 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.06 0.935 – 1.2 0.362 263 2655 exclusion phecode
615 Endometriosis Genitourinary 1.04 1 – 1.07 0.0317 3926 39388 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.05 0.924 – 1.18 0.478 286 2948 exclusion phecode
618 Genital prolapse Genitourinary 1.01 0.986 – 1.03 0.586 11276 112778 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 1.02 0.993 – 1.04 0.166 7137 71257 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.988 0.959 – 1.02 0.407 5202 51893 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.07 0.976 – 1.18 0.149 497 4959 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.05 0.968 – 1.14 0.235 657 6546 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1.02 1 – 1.05 0.0467 8422 84776 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.95 0.878 – 1.03 0.197 710 7086 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 1.03 0.994 – 1.07 0.105 3196 32240 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.04 0.997 – 1.08 0.0738 2772 27834 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.994 0.945 – 1.05 0.816 1706 17148 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.06 1 – 1.12 0.0504 1296 13081 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 0.924 0.722 – 1.18 0.528 68 700 exclusion phecode
621 Endometrial hyperplasia Genitourinary 1 0.939 – 1.06 0.989 1084 10924 exclusion phecode
622 Polyp of female genital organs Genitourinary 1.02 1 – 1.04 0.0495 10130 101623 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 1.02 0.999 – 1.05 0.0597 7594 76215 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 1.05 1.01 – 1.09 0.00734 3334 33340 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.02 0.963 – 1.08 0.48 1227 12348 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 1.04 0.968 – 1.12 0.271 766 7686 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.978 0.851 – 1.12 0.759 227 2273 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 1.06 0.962 – 1.17 0.229 421 4237 exclusion phecode
624.9 stress incontinence, female Genitourinary 1 0.973 – 1.03 0.961 5669 56746 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.03 0.995 – 1.08 0.0917 2775 28027 exclusion phecode
625.1 Dyspareunia Genitourinary 1.04 0.983 – 1.11 0.165 1146 11616 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.02 0.999 – 1.03 0.0711 15794 112253 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.01 0.99 – 1.03 0.407 13793 107348 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 1.19 0.977 – 1.45 0.0839 104 1083 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1.02 1 – 1.04 0.0408 9502 89743 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 1.02 0.972 – 1.07 0.436 1946 19327 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.996 0.963 – 1.03 0.839 3707 37196 exclusion phecode
626.2 Dysmenorrhea Genitourinary 1 0.953 – 1.05 0.947 1721 17429 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 1 0.851 – 1.18 0.962 157 1559 exclusion phecode
626.8 Infertility, female Genitourinary 1.11 1.05 – 1.17 0.000152 1342 13407 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.01 0.991 – 1.03 0.263 9971 100318 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 1.02 0.993 – 1.04 0.167 8683 87219 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.884 0.753 – 1.04 0.134 171 1777 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.999 0.937 – 1.06 0.966 1066 10655 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 0.934 0.829 – 1.05 0.264 303 3005 exclusion phecode
628 Ovarian cyst Genitourinary 1.04 1.01 – 1.07 0.00721 4598 46329 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.02 0.993 – 1.05 0.134 5127 35916 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.08 1.01 – 1.15 0.015 1118 11148 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.07 0.952 – 1.19 0.269 326 3253 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1 0.957 – 1.05 0.872 1934 17160 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.968 0.901 – 1.04 0.377 849 8501 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.04 0.979 – 1.1 0.21 1241 12158 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1 0.961 – 1.05 0.856 2306 19723 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.991 0.911 – 1.08 0.842 603 6060 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.02 0.961 – 1.09 0.492 1067 10610 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 1.01 0.789 – 1.29 0.945 70 688 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.99 0.929 – 1.05 0.748 1096 10934 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.02 0.91 – 1.15 0.7 303 3021 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.22 1.06 – 1.4 0.00516 210 2117 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.15 0.98 – 1.35 0.0876 148 1501 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.06 0.998 – 1.12 0.0574 1232 12268 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.997 0.954 – 1.04 0.905 2190 20563 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.859 0.66 – 1.12 0.261 66 669 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.897 0.788 – 1.02 0.102 274 2715 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.01 0.836 – 1.23 0.881 111 1115 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.05 0.912 – 1.22 0.484 190 1889 exclusion phecode
650 Normal delivery Pregnancy Complications 0.963 0.917 – 1.01 0.123 1890 18723 exclusion phecode
651 Multiple gestation Pregnancy Complications 1.03 0.921 – 1.15 0.615 338 3398 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1.04 0.988 – 1.09 0.134 1684 16301 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.994 0.939 – 1.05 0.823 1379 13468 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.12 0.884 – 1.41 0.354 72 725 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1 0.968 – 1.03 0.98 4238 29051 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.981 0.802 – 1.2 0.854 108 1066 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.994 0.95 – 1.04 0.781 2234 18166 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.966 0.881 – 1.06 0.455 527 5243 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.987 0.957 – 1.02 0.393 5224 29072 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.01 0.97 – 1.05 0.595 2507 20909 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.09 0.932 – 1.29 0.271 161 1606 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.986 0.867 – 1.12 0.833 259 2570 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.08 0.831 – 1.39 0.583 63 614 exclusion phecode
679 Complications of in utero procedures Dermatologic 1.26 0.96 – 1.65 0.0954 51 523 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.04 1.01 – 1.06 0.00398 6865 69556 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.02 0.931 – 1.11 0.715 541 5439 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.04 0.947 – 1.14 0.404 501 5028 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.03 1 – 1.06 0.0245 5227 52947 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.03 1 – 1.06 0.0268 5234 53007 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.03 1 – 1.06 0.0221 5192 52590 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.08 0.991 – 1.18 0.0809 559 5791 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.09 1.03 – 1.16 0.00235 1221 12916 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.06 1.01 – 1.11 0.00986 2202 22158 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.03 0.944 – 1.12 0.521 562 5718 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.06 0.954 – 1.19 0.265 340 3507 exclusion phecode
687 Symptoms affecting skin Dermatologic 1.03 0.938 – 1.13 0.552 511 5279 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.05 1.01 – 1.1 0.0285 2029 20681 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 0.996 0.878 – 1.13 0.947 269 2710 exclusion phecode
687.3 Changes in skin texture Dermatologic 1.05 0.85 – 1.29 0.665 92 1020 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.04 0.996 – 1.08 0.0812 2756 27915 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.04 1.01 – 1.08 0.00656 4626 55417 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 1.11 0.873 – 1.42 0.389 61 691 exclusion phecode
691 Congenital anomalies of skin Dermatologic 1.19 0.977 – 1.45 0.0832 105 1162 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 1.01 0.938 – 1.09 0.795 756 9521 exclusion phecode
694.1 Vitiligo Dermatologic 0.876 0.655 – 1.17 0.373 58 579 exclusion phecode
694.2 Other dyschromia Dermatologic 1.02 0.94 – 1.11 0.592 564 7568 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.07 0.885 – 1.29 0.489 109 1129 exclusion phecode
695 Erythematous conditions Dermatologic 1.04 0.995 – 1.09 0.08 2221 22931 exclusion phecode
695.1 Toxic erythema Dermatologic 1.07 0.882 – 1.3 0.482 105 1056 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.14 0.951 – 1.36 0.161 128 1297 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 1.27 0.973 – 1.66 0.0781 52 539 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.12 0.88 – 1.43 0.352 69 697 exclusion phecode
695.3 Rosacea Dermatologic 1.14 1.01 – 1.28 0.0355 275 2962 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.02 0.922 – 1.13 0.685 392 3986 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.07 0.896 – 1.27 0.46 125 1265 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 0.982 0.877 – 1.1 0.752 323 3301 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 0.973 0.9 – 1.05 0.494 725 7451 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1.07 0.934 – 1.23 0.318 220 2267 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.896 0.7 – 1.15 0.387 72 739 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.05 0.954 – 1.16 0.305 436 4502 exclusion phecode
696 Psoriasis and related disorders Dermatologic 1.01 0.966 – 1.06 0.669 2123 21676 exclusion phecode
696.4 Psoriasis Dermatologic 1.01 0.968 – 1.06 0.575 2072 21159 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 1.02 0.97 – 1.08 0.413 1572 16164 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 1.02 0.938 – 1.1 0.703 678 6834 exclusion phecode
697 Sarcoidosis Dermatologic 0.994 0.907 – 1.09 0.906 507 5196 exclusion phecode
698 Pruritus and related conditions Dermatologic 1.04 0.966 – 1.12 0.285 746 7548 exclusion phecode
700 Corns and callosities Dermatologic 1.06 0.935 – 1.2 0.36 269 2789 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.06 1.02 – 1.09 0.00102 3768 45100 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 1.08 0.856 – 1.36 0.521 76 836 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.07 1.01 – 1.12 0.011 1735 22700 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 1.04 0.799 – 1.34 0.793 58 587 exclusion phecode
701.4 Keloid scar Dermatologic 1.11 0.952 – 1.29 0.182 180 2100 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1.02 0.92 – 1.13 0.692 403 4417 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.14 0.909 – 1.43 0.26 80 974 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.11 1.07 – 1.14 9.51e-10 4021 52620 exclusion phecode
702.1 Actinic keratosis Dermatologic 1.22 1.17 – 1.28 8.81e-17 1714 24817 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 1.03 0.983 – 1.07 0.238 2380 29632 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.02 0.911 – 1.14 0.728 323 3385 exclusion phecode
703.1 Ingrowing nail Dermatologic 1.05 0.984 – 1.13 0.133 927 9341 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 1.06 1.03 – 1.09 3.09e-05 5014 50990 exclusion phecode
704.1 Alopecia Dermatologic 0.9 0.741 – 1.09 0.286 113 1239 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.793 0.6 – 1.05 0.103 61 744 exclusion phecode
705 Disorders of sweat glands Dermatologic 1.05 0.917 – 1.2 0.481 223 2222 exclusion phecode
705.3 Hidradenitis Dermatologic 1.03 0.891 – 1.2 0.669 182 1819 exclusion phecode
705.8 Hyperhidrosis Dermatologic 0.994 0.91 – 1.09 0.892 556 5651 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1.06 1.04 – 1.09 1.1e-07 7874 80355 exclusion phecode
706.1 Acne Dermatologic 0.877 0.685 – 1.12 0.301 73 755 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1.07 1.05 – 1.1 1.65e-09 8335 84902 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.02 0.973 – 1.07 0.393 1843 18779 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.03 0.961 – 1.11 0.401 867 8682 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.986 0.951 – 1.02 0.453 3281 33073 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.01 0.921 – 1.11 0.792 485 4902 exclusion phecode
709.3 Systemic sclerosis Dermatologic 1.03 0.874 – 1.2 0.753 166 1686 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.27 0.99 – 1.63 0.0596 61 630 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.983 0.943 – 1.02 0.407 2601 26145 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.05 0.964 – 1.14 0.261 577 5816 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.08 0.987 – 1.18 0.0941 532 5380 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.06 0.913 – 1.24 0.431 185 1878 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.09 0.983 – 1.21 0.0995 380 3858 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 1.04 0.94 – 1.16 0.426 409 4090 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.07 0.948 – 1.2 0.284 317 3185 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.06 0.849 – 1.33 0.6 76 770 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1 0.842 – 1.19 0.974 141 1449 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.01 0.785 – 1.31 0.918 63 648 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.02 0.994 – 1.06 0.121 4551 46543 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.03 1 – 1.07 0.0367 4113 42102 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1 0.953 – 1.06 0.885 1583 15983 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.17 0.956 – 1.44 0.126 107 1085 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.942 0.864 – 1.03 0.181 592 5967 exclusion phecode
716 Other arthropathies Musculoskeletal 1.01 0.999 – 1.02 0.0795 35684 256139 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.04 1.01 – 1.08 0.0251 3336 33646 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.02 1 – 1.03 0.0539 14846 149246 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.01 0.999 – 1.02 0.0735 34225 253125 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.03 0.963 – 1.09 0.43 1088 10860 exclusion phecode
720 Spinal stenosis Musculoskeletal 0.995 0.96 – 1.03 0.771 3536 35533 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1.04 1.01 – 1.06 0.00249 7515 75211 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.04 1.01 – 1.07 0.011 4834 48443 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.994 0.853 – 1.16 0.939 185 1830 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 1.06 0.946 – 1.19 0.32 342 3378 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 0.991 0.969 – 1.01 0.456 8616 86769 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.12 1.02 – 1.22 0.0147 499 4938 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.02 0.982 – 1.06 0.29 2712 27282 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.18 0.911 – 1.52 0.212 66 654 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.975 0.944 – 1.01 0.126 4240 42632 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 0.919 0.837 – 1.01 0.078 506 4970 exclusion phecode
723.1 Torticollis Musculoskeletal 1.1 0.895 – 1.34 0.373 105 1027 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.01 0.964 – 1.06 0.672 1981 19775 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 0.971 0.873 – 1.08 0.585 381 3883 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.967 0.87 – 1.08 0.541 384 3917 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.12 0.867 – 1.45 0.379 63 604 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.02 0.967 – 1.07 0.488 1564 15560 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.01 0.993 – 1.03 0.263 14092 141507 exclusion phecode
726.1 Enthesopathy Musculoskeletal 1.02 0.996 – 1.04 0.111 9203 92341 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.887 0.787 – 1 0.0491 317 3243 exclusion phecode
726.3 Bursitis Musculoskeletal 0.981 0.912 – 1.05 0.601 819 8271 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.999 0.975 – 1.02 0.956 7038 70854 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1 0.964 – 1.05 0.849 2606 26469 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 1.08 0.887 – 1.31 0.455 102 991 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.974 0.938 – 1.01 0.185 2999 30050 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 1.01 0.926 – 1.1 0.804 565 5629 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.955 0.85 – 1.07 0.44 331 3387 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.03 0.858 – 1.23 0.778 137 1379 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.02 0.981 – 1.05 0.362 3474 35138 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.968 0.872 – 1.07 0.533 399 4000 exclusion phecode
728.7 Fasciitis Musculoskeletal 1.03 0.99 – 1.06 0.157 3604 36342 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.02 0.987 – 1.06 0.201 3286 33217 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 0.995 0.968 – 1.02 0.732 5765 58100 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.02 0.956 – 1.09 0.533 968 9761 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.868 0.701 – 1.07 0.194 98 976 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.965 0.848 – 1.1 0.586 261 2664 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.984 0.862 – 1.12 0.812 247 2518 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.924 0.838 – 1.02 0.115 456 4537 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.886 0.764 – 1.03 0.111 200 2007 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.974 0.74 – 1.28 0.854 57 561 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.01 0.956 – 1.06 0.839 1688 17173 exclusion phecode
733.2 Cyst of bone Musculoskeletal 0.932 0.824 – 1.05 0.259 295 3000 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.973 0.883 – 1.07 0.589 450 5182 exclusion phecode
733.6 Costochondritis Musculoskeletal 1.14 0.942 – 1.37 0.181 125 1229 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.989 0.931 – 1.05 0.713 1193 11896 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.1 0.908 – 1.33 0.336 116 1161 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1 0.983 – 1.03 0.684 9164 92639 exclusion phecode
735.1 Flat foot Musculoskeletal 1.03 0.882 – 1.21 0.691 181 1833 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 1.01 0.978 – 1.04 0.597 4831 48818 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.987 0.94 – 1.04 0.615 1838 18578 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 1.03 0.973 – 1.08 0.333 1484 14974 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1 0.979 – 1.03 0.726 6351 64147 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 0.992 0.941 – 1.05 0.752 1560 15653 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.12 0.981 – 1.28 0.095 237 2378 exclusion phecode
737 Curvature of spine Musculoskeletal 1.11 1.04 – 1.18 0.00151 1068 10869 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.1 1.03 – 1.17 0.00452 1003 10225 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.01 0.965 – 1.06 0.607 1823 18304 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.03 0.972 – 1.09 0.337 1447 14544 exclusion phecode
739 Contracture of joint Musculoskeletal 1.1 1 – 1.21 0.0504 471 4717 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.01 1 – 1.03 0.0307 26373 222646 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.01 0.999 – 1.03 0.0723 16614 162328 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.02 0.997 – 1.04 0.0962 8573 85918 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.09 0.976 – 1.23 0.123 331 3374 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.1 1.01 – 1.2 0.0235 555 5687 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.02 1 – 1.04 0.0267 11606 117760 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1 0.966 – 1.04 0.939 3413 34385 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 1.19 0.98 – 1.45 0.079 99 982 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.01 0.931 – 1.11 0.74 585 5926 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.961 0.807 – 1.14 0.651 145 1479 exclusion phecode
741.4 Joint effusions Musculoskeletal 0.986 0.932 – 1.04 0.618 1350 13657 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 0.888 0.724 – 1.09 0.257 105 1052 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 1.06 0.799 – 1.4 0.701 54 524 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1 0.966 – 1.05 0.817 2744 27631 exclusion phecode
742.1 Loose body in joint Musculoskeletal 0.866 0.769 – 0.977 0.0191 322 3231 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.1 0.899 – 1.35 0.348 95 944 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 0.973 0.887 – 1.07 0.567 479 4840 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 1.02 0.977 – 1.07 0.317 1925 19389 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.02 0.992 – 1.04 0.196 6922 72676 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.02 0.995 – 1.05 0.109 5815 61453 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.02 0.993 – 1.05 0.138 5229 53334 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 0.996 0.908 – 1.09 0.93 494 5040 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.02 0.932 – 1.13 0.616 489 4985 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.984 0.913 – 1.06 0.685 772 7875 exclusion phecode
745 Pain in joint Musculoskeletal 1.02 0.997 – 1.05 0.0879 7679 77024 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.962 0.923 – 1 0.0639 2673 26840 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.959 0.919 – 1 0.0522 2504 25157 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1 0.916 – 1.09 0.989 562 5633 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.958 0.831 – 1.1 0.548 228 2287 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.932 0.886 – 0.981 0.00715 1720 17295 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.01 0.857 – 1.18 0.93 163 1628 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.971 0.858 – 1.1 0.635 284 2923 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 1.03 0.953 – 1.12 0.42 647 6611 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.954 0.845 – 1.08 0.443 304 3124 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.934 0.799 – 1.09 0.392 178 1821 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.1 0.986 – 1.23 0.0868 340 3464 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.09 0.954 – 1.25 0.198 222 2186 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.15 0.942 – 1.41 0.169 104 1139 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.03 0.975 – 1.09 0.296 1444 14782 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.01 0.931 – 1.09 0.828 673 6738 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.02 0.923 – 1.13 0.699 443 4445 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.982 0.852 – 1.13 0.804 216 2140 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.03 0.959 – 1.11 0.394 776 8070 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 1.02 0.921 – 1.14 0.68 383 4089 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.03 0.915 – 1.16 0.624 318 3230 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.04 0.932 – 1.17 0.459 320 3212 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.06 0.936 – 1.21 0.345 248 2482 exclusion phecode
752.11 Spina bifida Congenital Anomalies 1.15 1 – 1.32 0.0489 203 2046 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.13 0.904 – 1.41 0.283 76 754 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.775 0.632 – 0.949 0.0139 124 1236 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.827 0.632 – 1.08 0.165 74 737 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.07 0.881 – 1.31 0.478 104 1061 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.06 0.962 – 1.18 0.226 393 4123 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.11 0.961 – 1.28 0.158 194 2019 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.998 0.846 – 1.18 0.98 155 1566 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.942 0.767 – 1.16 0.568 104 1037 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.04 0.949 – 1.13 0.427 559 5675 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.07 0.85 – 1.35 0.566 75 793 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.02 0.92 – 1.13 0.719 418 4210 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.963 0.802 – 1.16 0.686 137 1652 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.939 0.71 – 1.24 0.656 55 802 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.04 0.907 – 1.2 0.545 208 2095 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.967 0.779 – 1.2 0.762 94 930 exclusion phecode
760 Back pain Symptoms 1.01 0.99 – 1.03 0.346 10715 107406 exclusion phecode
761 Cervicalgia Symptoms 1.04 0.99 – 1.09 0.118 1725 17327 exclusion phecode
764 Sciatica Symptoms 0.964 0.923 – 1.01 0.104 2287 22896 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.942 0.884 – 1 0.0612 1121 11319 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.08 0.995 – 1.18 0.0664 603 6077 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.01 0.94 – 1.09 0.774 823 8396 exclusion phecode
771.1 Swelling of limb Symptoms 0.992 0.962 – 1.02 0.622 4428 44519 exclusion phecode
772 Symptoms of the muscles Symptoms 1.08 0.996 – 1.17 0.0639 626 6333 exclusion phecode
773 Pain in limb Symptoms 1.03 1 – 1.06 0.0351 5962 59987 exclusion phecode
780 Hypothermia/Chills Symptoms 1.06 0.899 – 1.25 0.491 160 1646 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.989 0.941 – 1.04 0.665 1785 18033 exclusion phecode
782.3 Edema Symptoms 1.04 0.991 – 1.1 0.103 1563 15789 exclusion phecode
782.6 Pallor and flushing Symptoms 1.11 0.951 – 1.31 0.179 167 1695 exclusion phecode
783 Fever of unknown origin Symptoms 0.981 0.947 – 1.02 0.27 3716 37655 exclusion phecode
785 Abdominal pain Symptoms 1.02 1.01 – 1.03 0.00148 38557 291645 exclusion phecode
788 Syncope and collapse Symptoms 1.04 1.02 – 1.06 0.000432 8686 87127 exclusion phecode
789 Nausea and vomiting Symptoms 1.04 1.02 – 1.06 0.00019 11079 111580 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 0.994 0.828 – 1.19 0.951 137 1445 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.14 0.908 – 1.44 0.258 82 809 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1 0.974 – 1.03 0.954 5997 60716 exclusion phecode
791 Gangrene Symptoms 0.848 0.771 – 0.933 0.000704 523 5277 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1.2 0.985 – 1.46 0.0709 92 933 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.04 0.866 – 1.26 0.657 124 1276 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.05 0.958 – 1.14 0.308 536 5413 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.949 0.784 – 1.15 0.591 120 1173 exclusion phecode
797 Shock Symptoms 0.9 0.755 – 1.07 0.236 151 1486 exclusion phecode
797.1 Cardiogenic shock Symptoms 0.856 0.689 – 1.06 0.161 100 975 exclusion phecode
798 Malaise and fatigue Symptoms 1.02 0.983 – 1.06 0.3 3238 32926 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 0.98 0.897 – 1.07 0.646 571 5730 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.01 0.983 – 1.03 0.505 6767 67723 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.988 0.939 – 1.04 0.633 1743 17365 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.888 0.75 – 1.05 0.166 163 1616 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.01 0.965 – 1.06 0.685 2091 20902 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.972 0.9 – 1.05 0.47 732 7345 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.04 0.993 – 1.09 0.1 2139 21317 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.06 1.01 – 1.12 0.0118 1775 17762 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 0.985 0.91 – 1.07 0.715 692 6915 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 1.02 0.998 – 1.05 0.0745 8011 80012 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1.04 0.992 – 1.1 0.0999 1625 16248 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.02 0.986 – 1.05 0.301 5047 50359 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.05 0.993 – 1.11 0.0853 1466 14674 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.99 0.954 – 1.03 0.586 3224 32310 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.05 0.992 – 1.11 0.0932 1312 13065 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.08 1 – 1.17 0.0393 749 7462 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.05 0.989 – 1.11 0.114 1253 12539 exclusion phecode
817 Concussion Injuries & Poisonings 1.28 1.12 – 1.46 0.000258 240 2334 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.958 0.873 – 1.05 0.369 505 4991 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.01 0.976 – 1.05 0.458 2864 28674 exclusion phecode
823 Torus fracture Injuries & Poisonings 1.02 0.968 – 1.07 0.468 1624 16208 exclusion phecode
830 Dislocation Injuries & Poisonings 1.03 0.984 – 1.08 0.196 2015 20234 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 1.01 0.988 – 1.02 0.532 14650 147201 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 1.04 0.947 – 1.14 0.423 509 5075 exclusion phecode
840 Sprains and strains Injuries & Poisonings 1.01 0.919 – 1.12 0.781 452 4531 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.06 1.03 – 1.09 6.54e-05 4955 50711 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1 0.842 – 1.2 0.969 136 1512 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.02 0.925 – 1.12 0.722 466 4808 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.996 0.947 – 1.05 0.871 1722 17455 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.981 0.923 – 1.04 0.546 1182 11901 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.01 0.969 – 1.05 0.746 3014 30372 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.03 0.987 – 1.06 0.194 3105 31361 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 0.957 0.74 – 1.24 0.737 62 662 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.04 1 – 1.07 0.0488 3375 33767 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.06 0.934 – 1.2 0.376 265 2619 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1.06 0.915 – 1.22 0.461 193 1879 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.03 0.995 – 1.08 0.0845 2795 28007 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.06 0.922 – 1.22 0.412 212 2105 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.99 0.755 – 1.3 0.94 66 664 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 0.982 0.95 – 1.02 0.284 3920 39293 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.19 0.91 – 1.55 0.206 53 510 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.11 0.904 – 1.36 0.317 89 866 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.979 0.836 – 1.15 0.791 170 1729 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 0.991 0.9 – 1.09 0.857 450 4557 exclusion phecode
873 Broken tooth Injuries & Poisonings 0.886 0.771 – 1.02 0.0894 224 2210 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1 0.856 – 1.18 0.965 162 1666 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 0.981 0.834 – 1.15 0.816 155 1517 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 0.996 0.94 – 1.06 0.894 1266 12718 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.05 1.02 – 1.09 0.00183 4085 41042 exclusion phecode
916 Contusion Injuries & Poisonings 1.04 0.987 – 1.1 0.135 1388 13980 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.959 0.817 – 1.13 0.608 174 1754 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.23 1.09 – 1.38 0.000859 273 3738 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 1.31 1.12 – 1.52 0.000551 166 2421 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.02 0.973 – 1.07 0.414 1974 20190 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.9 0.777 – 1.04 0.161 203 2159 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.03 0.841 – 1.27 0.763 97 1001 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.08 0.988 – 1.18 0.0894 535 5314 exclusion phecode
947 Urticaria Injuries & Poisonings 1.04 0.936 – 1.17 0.437 358 3582 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.1 0.992 – 1.22 0.0702 378 3877 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.12 1.01 – 1.24 0.0247 405 4068 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.965 0.848 – 1.1 0.589 256 2580 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.955 0.868 – 1.05 0.349 476 4763 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 0.931 0.691 – 1.26 0.64 53 533 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.761 0.592 – 0.978 0.0332 71 718 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1 0.988 – 1.02 0.603 17193 175014 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.998 0.981 – 1.01 0.796 15056 153257 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.06 0.959 – 1.18 0.247 405 4036 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.05 0.977 – 1.13 0.187 829 8418 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.06 0.95 – 1.18 0.296 350 3571 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.03 0.926 – 1.16 0.545 343 3508 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.94 0.814 – 1.09 0.398 213 2172 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.01 0.892 – 1.15 0.833 270 2728 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.04 0.916 – 1.18 0.535 264 2670 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.988 0.962 – 1.02 0.392 5836 58886 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.04 0.979 – 1.11 0.193 1082 11056 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.08 0.983 – 1.19 0.11 463 4656 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.06 0.957 – 1.18 0.26 390 3930 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.03 0.937 – 1.13 0.559 487 4967 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.994 0.909 – 1.09 0.895 558 5634 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1 0.954 – 1.05 0.984 1887 19031 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.926 0.793 – 1.08 0.329 187 1859 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.969 0.85 – 1.1 0.637 255 2634 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.948 0.75 – 1.2 0.658 80 833 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.13 0.929 – 1.38 0.217 105 1048 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.94 0.759 – 1.16 0.572 97 971 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.961 0.741 – 1.25 0.762 63 620 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.989 0.744 – 1.31 0.939 54 560 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.12 0.972 – 1.28 0.119 224 2258 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.04 0.959 – 1.12 0.353 676 6763 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.942 0.81 – 1.1 0.439 195 1943 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.16 0.891 – 1.51 0.272 61 601 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.24 1.01 – 1.52 0.0367 100 1013 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.805 0.652 – 0.994 0.044 108 1090 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.981 0.781 – 1.23 0.867 84 857 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.01 0.971 – 1.05 0.656 2890 29801 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1 0.965 – 1.04 0.874 2861 29032 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1 0.965 – 1.04 0.874 2861 29032 exclusion phecode
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