Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Squamous cell carcinoma UK Biobank (UKB) PheWAS analysis

Squamous cell carcinoma — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID prsweb-phecode172-22-gwas-catalog-r2019-05-03-x172-22-p-5e-08-ukb-20200608Legacy P_5e-08GWAS HitsGWAS Catalog (2019-05-03)

Evaluation cohort: UK Biobank (UKB).

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240 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.01 0.991 – 1.04 0.235 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.03 0.988 – 1.07 0.165 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.03 0.952 – 1.12 0.434 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 1.03 0.959 – 1.1 0.437 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.14 0.873 – 1.48 0.342 55 550 all phecode
010 Tuberculosis Infectious Diseases 1.02 0.868 – 1.2 0.805 166 1659 all phecode
038 Septicemia Infectious Diseases 1.01 0.981 – 1.05 0.413 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.04 0.966 – 1.11 0.315 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.03 0.942 – 1.13 0.482 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 1.01 0.992 – 1.03 0.263 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.03 0.991 – 1.07 0.141 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 0.996 0.946 – 1.05 0.888 1641 16433 all phecode
041.4 E. coli Infectious Diseases 1.02 0.978 – 1.06 0.378 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 0.941 0.848 – 1.04 0.243 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.966 0.778 – 1.2 0.755 95 949 all phecode
054 Herpes simplex Infectious Diseases 1.08 0.941 – 1.24 0.268 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 1.05 0.963 – 1.14 0.274 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 0.881 0.688 – 1.13 0.319 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.21 1.02 – 1.44 0.0277 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.05 0.924 – 1.2 0.447 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.04 0.919 – 1.18 0.521 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.04 0.939 – 1.14 0.482 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.13 0.954 – 1.34 0.16 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.17 0.976 – 1.41 0.088 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 1.11 1.04 – 1.18 0.00144 1004 10036 all phecode
079 Viral infection Infectious Diseases 1.01 0.975 – 1.06 0.471 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 0.958 0.743 – 1.24 0.742 64 640 all phecode
080 Postoperative infection Infectious Diseases 1.01 0.975 – 1.04 0.695 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.03 0.984 – 1.07 0.231 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.07 0.85 – 1.36 0.551 71 709 all phecode
1000 Burns Injuries & Poisonings 0.984 0.903 – 1.07 0.709 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 1.02 0.963 – 1.08 0.472 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1 0.977 – 1.03 0.73 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.02 0.901 – 1.15 0.792 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 1.02 0.969 – 1.08 0.41 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 0.98 0.863 – 1.11 0.756 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 1.05 0.921 – 1.19 0.485 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.04 0.976 – 1.11 0.215 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 1.02 1 – 1.05 0.0503 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 1.02 0.99 – 1.04 0.212 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.01 0.993 – 1.04 0.18 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 1.01 0.834 – 1.22 0.923 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 0.978 0.869 – 1.1 0.713 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.02 0.797 – 1.31 0.875 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 1.02 0.987 – 1.05 0.256 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.02 1 – 1.03 0.0529 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.884 0.78 – 1 0.0516 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 0.881 0.778 – 0.999 0.0481 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.04 0.823 – 1.3 0.768 74 756 all phecode
110.12 Althete's foot Infectious Diseases 0.801 0.671 – 0.956 0.0138 141 1410 all phecode
112 Candidiasis Infectious Diseases 1.05 0.999 – 1.09 0.0535 2126 21275 all phecode
117 Mycoses Infectious Diseases 0.921 0.811 – 1.05 0.202 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 0.904 0.767 – 1.06 0.226 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 0.922 0.728 – 1.17 0.496 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 0.889 0.687 – 1.15 0.374 69 689 all phecode
134 Helminthiases Infectious Diseases 1.2 1.01 – 1.43 0.0412 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.17 0.974 – 1.42 0.0927 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.936 0.808 – 1.08 0.378 205 2050 all phecode
145 Cancer of mouth Neoplasms 1.08 0.994 – 1.17 0.0706 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 0.93 0.827 – 1.05 0.229 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.21 0.989 – 1.48 0.0646 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.08 0.835 – 1.4 0.558 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.05 0.966 – 1.14 0.258 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 1.03 0.904 – 1.18 0.65 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 1.05 0.93 – 1.19 0.423 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 1.31 0.991 – 1.72 0.0577 57 570 all phecode
150 Cancer of esophagus Neoplasms 0.97 0.9 – 1.05 0.424 762 7630 all phecode
151 Cancer of stomach Neoplasms 0.983 0.902 – 1.07 0.697 569 5696 all phecode
153 Colorectal cancer Neoplasms 1.01 0.977 – 1.04 0.642 4580 45799 all phecode
153.2 Colon cancer Neoplasms 1.01 0.976 – 1.05 0.495 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.01 0.964 – 1.05 0.725 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.939 0.846 – 1.04 0.241 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1 0.852 – 1.18 0.975 158 1580 all phecode
157 Pancreatic cancer Neoplasms 0.993 0.916 – 1.08 0.866 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.01 0.95 – 1.08 0.716 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1 0.974 – 1.03 0.906 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1 0.865 – 1.17 0.949 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.839 0.723 – 0.973 0.0204 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.04 0.898 – 1.21 0.59 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 1.28 0.988 – 1.65 0.0622 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 1.06 1.02 – 1.1 0.002 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.06 1.01 – 1.11 0.0106 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 1.08 0.984 – 1.19 0.103 437 4364 all phecode
170.1 Bone cancer Neoplasms 1.19 1 – 1.41 0.0503 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 1.05 0.942 – 1.18 0.364 331 3303 all phecode
172 Skin cancer Neoplasms 1.31 1.29 – 1.33 3.71e-202 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.29 1.24 – 1.34 2.01e-37 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 1.29 1.24 – 1.34 1.77e-37 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1.32 1.3 – 1.35 1.17e-179 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.49 1.38 – 1.62 2.1e-23 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.24 1.07 – 1.44 0.00485 181 1818 all phecode
174 Breast cancer Neoplasms 1.02 1 – 1.04 0.0235 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 1.02 1 – 1.04 0.021 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.02 1 – 1.04 0.0205 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.89 0.731 – 1.08 0.244 115 1148 all phecode
175 Acquired absence of breast Neoplasms 1.03 0.986 – 1.07 0.198 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 0.987 0.944 – 1.03 0.563 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 1 0.886 – 1.13 0.968 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.984 0.94 – 1.03 0.495 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 0.981 0.925 – 1.04 0.505 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 1.06 1 – 1.12 0.0469 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.1 1.03 – 1.18 0.00452 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.1 1.03 – 1.17 0.00576 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.965 0.857 – 1.09 0.553 305 3049 all phecode
185 Cancer of prostate Neoplasms 0.99 0.963 – 1.02 0.455 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 1 0.907 – 1.1 0.994 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.01 0.789 – 1.29 0.947 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 1.03 0.911 – 1.16 0.66 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1 0.823 – 1.22 0.993 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1 0.969 – 1.03 0.953 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.988 0.927 – 1.05 0.701 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.98 0.918 – 1.05 0.541 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.16 0.893 – 1.5 0.269 66 660 all phecode
189.2 Cancer of bladder Neoplasms 1.02 0.974 – 1.06 0.444 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1 0.955 – 1.05 0.987 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.14 0.964 – 1.35 0.124 144 1439 all phecode
190 Cancer of eye Neoplasms 1.26 1.08 – 1.46 0.00272 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.04 0.965 – 1.13 0.284 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1.02 0.937 – 1.11 0.626 566 5650 all phecode
191.11 Cancer of brain Neoplasms 1.02 0.932 – 1.12 0.67 525 5240 all phecode
193 Thyroid cancer Neoplasms 1.08 0.968 – 1.2 0.172 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 1.02 0.822 – 1.26 0.878 95 949 all phecode
195 Cancer, suspected or other Neoplasms 1.08 1.06 – 1.1 3.74e-22 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.08 1.07 – 1.1 5.75e-23 16267 159497 all phecode
197 Chemotherapy Neoplasms 1.03 1.02 – 1.04 3.95e-05 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 1.03 1.01 – 1.06 0.00178 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.04 1.01 – 1.07 0.00341 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.02 0.98 – 1.07 0.296 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.03 0.978 – 1.09 0.25 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.03 0.99 – 1.07 0.144 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.06 0.99 – 1.14 0.0904 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.03 0.984 – 1.08 0.21 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.21 1.05 – 1.4 0.00921 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.02 0.97 – 1.08 0.384 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 0.895 0.721 – 1.11 0.311 95 950 all phecode
200 Myeloproliferative disease Neoplasms 1.02 0.951 – 1.09 0.641 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 1.03 0.922 – 1.14 0.64 387 3867 all phecode
201 Hodgkin's disease Neoplasms 1.07 0.945 – 1.22 0.281 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.04 0.998 – 1.09 0.0601 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.05 1 – 1.1 0.0391 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 1.04 0.933 – 1.16 0.46 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 1.08 0.995 – 1.18 0.0662 581 5824 all phecode
204 Leukemia Neoplasms 1.03 0.977 – 1.08 0.289 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 1.08 0.99 – 1.18 0.082 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.924 0.689 – 1.24 0.596 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.09 0.991 – 1.19 0.0782 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 0.965 0.874 – 1.06 0.473 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 1 0.891 – 1.13 0.973 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.913 0.766 – 1.09 0.31 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 1.06 0.974 – 1.16 0.172 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 1.03 1.01 – 1.04 0.000151 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.03 0.968 – 1.11 0.319 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.02 0.988 – 1.05 0.249 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.949 0.849 – 1.06 0.352 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.12 1 – 1.26 0.0454 318 3187 all phecode
214 Lipoma Neoplasms 0.998 0.973 – 1.02 0.906 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1 0.972 – 1.03 0.892 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.01 0.946 – 1.07 0.831 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 0.957 0.935 – 0.98 0.000348 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.05 0.965 – 1.14 0.274 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.06 0.976 – 1.15 0.165 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 0.992 0.971 – 1.01 0.439 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 1 0.981 – 1.02 0.893 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.937 0.837 – 1.05 0.254 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 1.04 0.988 – 1.1 0.13 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.02 0.889 – 1.18 0.76 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.882 0.745 – 1.04 0.145 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.03 0.88 – 1.2 0.724 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 1.22 1.03 – 1.45 0.0251 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.4 1.11 – 1.78 0.00531 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.01 0.94 – 1.09 0.751 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.02 0.941 – 1.09 0.698 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.04 0.804 – 1.35 0.753 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.07 0.94 – 1.21 0.321 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.04 0.968 – 1.12 0.281 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.18 1.01 – 1.37 0.0353 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.05 0.944 – 1.17 0.36 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.986 0.877 – 1.11 0.815 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.04 0.983 – 1.09 0.19 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.866 0.829 – 0.904 7.57e-11 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.965 0.886 – 1.05 0.415 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.984 0.924 – 1.05 0.612 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.928 0.844 – 1.02 0.125 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.04 0.96 – 1.13 0.338 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.08 1.03 – 1.13 0.00124 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 1.11 1.01 – 1.22 0.0252 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.15 0.938 – 1.4 0.182 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.18 0.997 – 1.4 0.0543 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 1.03 1.01 – 1.05 0.000287 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.05 0.989 – 1.12 0.105 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.15 0.935 – 1.41 0.186 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.03 1.01 – 1.05 0.000697 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 1.04 0.92 – 1.17 0.535 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.09 0.951 – 1.26 0.211 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.08 0.939 – 1.25 0.274 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.07 0.965 – 1.19 0.197 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.02 1 – 1.03 0.0111 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.07 1.03 – 1.11 0.00062 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.11 0.974 – 1.27 0.117 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.22 0.96 – 1.54 0.105 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.07 0.975 – 1.18 0.153 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.13 0.965 – 1.33 0.127 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.02 1 – 1.03 0.0546 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.18 0.975 – 1.44 0.0878 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.04 0.898 – 1.19 0.634 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.04 0.972 – 1.11 0.26 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.03 0.943 – 1.13 0.482 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 0.99 0.914 – 1.07 0.814 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.02 0.895 – 1.15 0.801 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.987 0.891 – 1.09 0.805 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.994 0.828 – 1.19 0.944 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.03 0.917 – 1.15 0.655 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.03 0.971 – 1.09 0.336 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.09 1.02 – 1.17 0.00918 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.01 0.942 – 1.08 0.768 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1 0.93 – 1.08 0.986 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.986 0.827 – 1.18 0.871 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.03 0.956 – 1.12 0.397 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.977 0.838 – 1.14 0.764 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.996 0.805 – 1.23 0.97 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.1 0.967 – 1.25 0.149 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.15 0.925 – 1.43 0.208 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.996 0.844 – 1.17 0.958 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.968 0.893 – 1.05 0.436 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.08 0.932 – 1.26 0.293 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.969 0.794 – 1.18 0.758 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.26 0.996 – 1.59 0.0541 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.958 0.86 – 1.07 0.43 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.957 0.859 – 1.07 0.423 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 0.958 0.838 – 1.1 0.529 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.922 0.8 – 1.06 0.267 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 1.19 1.01 – 1.4 0.0415 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.13 0.956 – 1.34 0.151 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.863 0.702 – 1.06 0.16 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.09 0.922 – 1.28 0.319 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.02 0.888 – 1.18 0.762 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 0.934 0.703 – 1.24 0.639 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 1.05 0.979 – 1.13 0.165 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.07 1.01 – 1.13 0.0305 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.08 1 – 1.17 0.0394 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.03 0.936 – 1.14 0.531 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.943 0.752 – 1.18 0.609 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.02 0.893 – 1.17 0.764 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 1.09 0.974 – 1.22 0.134 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.09 0.974 – 1.23 0.131 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.09 0.965 – 1.24 0.16 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.07 0.921 – 1.24 0.386 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.02 0.836 – 1.24 0.873 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.07 0.84 – 1.37 0.567 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.962 0.813 – 1.14 0.654 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.926 0.771 – 1.11 0.412 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.01 0.995 – 1.02 0.257 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.01 0.995 – 1.02 0.286 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.01 0.994 – 1.02 0.353 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.07 0.815 – 1.4 0.633 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.957 0.813 – 1.13 0.592 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.1 0.954 – 1.27 0.191 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1 0.968 – 1.04 0.948 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 1 0.967 – 1.04 0.854 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.08 0.894 – 1.31 0.412 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.01 0.923 – 1.1 0.898 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1 0.914 – 1.09 0.995 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.02 0.979 – 1.07 0.296 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.97 0.894 – 1.05 0.457 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.08 0.972 – 1.2 0.151 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.07 1 – 1.13 0.0365 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.08 0.924 – 1.27 0.325 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.03 1 – 1.06 0.0186 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.02 0.99 – 1.06 0.176 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.02 0.896 – 1.17 0.742 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.06 1.01 – 1.11 0.0249 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.02 0.953 – 1.09 0.587 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.01 0.953 – 1.06 0.806 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.03 0.969 – 1.09 0.348 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 1.04 0.979 – 1.11 0.186 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 0.888 0.722 – 1.09 0.261 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.03 0.993 – 1.07 0.112 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 1.01 0.913 – 1.11 0.908 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 0.976 0.817 – 1.17 0.792 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.05 0.977 – 1.12 0.189 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.998 0.894 – 1.11 0.968 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.02 0.885 – 1.17 0.825 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.08 0.81 – 1.43 0.611 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.02 0.996 – 1.04 0.12 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 1.02 0.996 – 1.04 0.115 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 0.893 0.714 – 1.12 0.323 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.09 0.847 – 1.39 0.514 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.06 0.929 – 1.21 0.388 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1.08 0.934 – 1.25 0.298 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.07 0.899 – 1.27 0.462 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.02 0.894 – 1.16 0.784 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 1.03 1 – 1.05 0.0212 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.03 1 – 1.05 0.0261 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.12 1.02 – 1.24 0.0162 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 1.11 1.04 – 1.18 0.00118 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 1.12 1.05 – 1.19 0.000322 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 1.12 1.04 – 1.21 0.00247 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.941 0.804 – 1.1 0.448 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 1.2 1.03 – 1.39 0.0172 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 0.935 0.713 – 1.23 0.625 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 0.964 0.812 – 1.14 0.674 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.14 0.887 – 1.48 0.299 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.874 0.691 – 1.11 0.261 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 0.978 0.819 – 1.17 0.808 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.889 0.721 – 1.1 0.268 103 1059 all phecode
284 Aplastic anemia Hematopoietic 1.07 0.965 – 1.18 0.209 435 4357 all phecode
285 Other anemias Hematopoietic 1.03 1.01 – 1.05 0.000557 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.96 0.846 – 1.09 0.521 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.08 1 – 1.17 0.0481 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.09 0.983 – 1.2 0.106 414 4147 all phecode
286 Coagulation defects Hematopoietic 1.03 0.966 – 1.11 0.326 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 1.03 0.931 – 1.13 0.614 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 0.922 0.749 – 1.13 0.439 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.04 0.923 – 1.18 0.503 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.08 0.832 – 1.41 0.556 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.04 0.842 – 1.29 0.694 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.09 0.98 – 1.21 0.111 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.03 0.976 – 1.08 0.308 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.08 0.903 – 1.29 0.403 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 0.943 0.697 – 1.27 0.702 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 1.02 0.964 – 1.07 0.552 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.04 0.941 – 1.15 0.434 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.962 0.762 – 1.22 0.747 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 1.02 0.989 – 1.06 0.191 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 1.01 0.976 – 1.05 0.516 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 1.01 0.978 – 1.05 0.448 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 1.06 0.833 – 1.35 0.631 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.08 1 – 1.16 0.0451 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.11 0.978 – 1.25 0.108 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 1.05 1 – 1.09 0.032 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 0.977 0.891 – 1.07 0.617 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.04 0.918 – 1.17 0.553 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.14 0.922 – 1.41 0.223 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.08 1.03 – 1.13 0.00104 1929 19281 all phecode
290.1 Dementias Mental Disorders 1.08 1.01 – 1.16 0.018 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 1.03 0.932 – 1.13 0.581 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 1.21 1.05 – 1.39 0.00867 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.07 0.986 – 1.16 0.105 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.08 0.846 – 1.38 0.538 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.12 1.04 – 1.2 0.00192 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.952 0.793 – 1.14 0.601 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.09 0.967 – 1.24 0.153 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 1.18 1.07 – 1.3 0.000986 436 4376 all phecode
292 Neurological disorders Mental Disorders 1.01 0.983 – 1.05 0.396 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.05 0.994 – 1.11 0.0836 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 1.06 0.908 – 1.23 0.473 190 1907 all phecode
292.3 Memory loss Mental Disorders 0.983 0.907 – 1.07 0.679 696 6978 all phecode
292.4 Altered mental status Mental Disorders 0.993 0.949 – 1.04 0.753 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 1.11 0.985 – 1.24 0.0881 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 1.02 0.977 – 1.07 0.335 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.04 0.976 – 1.12 0.208 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.01 0.94 – 1.08 0.799 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 0.996 0.915 – 1.09 0.934 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 0.979 0.836 – 1.15 0.788 178 1780 all phecode
295.3 Psychosis Mental Disorders 1 0.852 – 1.18 0.992 169 1710 all phecode
296 Mood disorders Mental Disorders 1.01 0.991 – 1.03 0.303 12372 123822 all phecode
296.1 Bipolar Mental Disorders 1.04 0.972 – 1.1 0.283 1059 10599 all phecode
296.2 Depression Mental Disorders 1.01 0.989 – 1.03 0.41 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 0.941 0.842 – 1.05 0.282 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.962 0.859 – 1.08 0.5 311 3070 all phecode
300 Anxiety disorders Mental Disorders 1.02 0.995 – 1.05 0.113 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 1.02 0.992 – 1.05 0.168 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1.05 0.889 – 1.25 0.55 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.04 0.965 – 1.13 0.283 707 7065 all phecode
300.13 Phobia Mental Disorders 0.988 0.9 – 1.08 0.795 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.15 0.97 – 1.36 0.109 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 1.12 0.85 – 1.47 0.426 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 1.12 0.928 – 1.35 0.24 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.958 0.791 – 1.16 0.658 113 1129 all phecode
301 Personality disorders Mental Disorders 1.06 0.951 – 1.19 0.275 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.09 0.911 – 1.32 0.332 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.976 0.861 – 1.11 0.705 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.04 0.948 – 1.15 0.383 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 1.09 0.976 – 1.22 0.127 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 1.01 0.845 – 1.21 0.896 123 1229 all phecode
304 Adjustment reaction Mental Disorders 1.01 0.894 – 1.14 0.87 293 2936 all phecode
305.2 Eating disorder Mental Disorders 1.09 0.875 – 1.35 0.453 90 900 all phecode
306 Other mental disorder Mental Disorders 1.02 1 – 1.03 0.00642 28056 230087 all phecode
306.9 Tension headache Mental Disorders 1 0.89 – 1.13 0.99 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 1.02 0.803 – 1.28 0.898 76 770 all phecode
313.3 Autism Mental Disorders 1.13 0.849 – 1.5 0.409 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 0.966 0.867 – 1.08 0.54 351 3517 all phecode
315.1 Learning disorder Mental Disorders 1.28 1.09 – 1.51 0.0022 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 1.1 0.89 – 1.35 0.388 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 1.05 1.02 – 1.08 0.00069 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.969 0.743 – 1.26 0.813 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 1.04 1.02 – 1.06 4.23e-06 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 1.04 1.02 – 1.07 0.000119 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.07 0.998 – 1.15 0.0576 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 1.01 0.995 – 1.03 0.195 19359 185465 all phecode
320 Meningitis Neurological 0.927 0.839 – 1.02 0.136 444 4447 all phecode
323 Encephalitis Neurological 0.983 0.877 – 1.1 0.764 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 0.904 0.702 – 1.16 0.434 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 0.976 0.864 – 1.1 0.7 292 2916 all phecode
327 Sleep disorders Neurological 1.03 0.968 – 1.09 0.368 1164 11659 all phecode
327.3 Sleep apnea Neurological 1.02 0.987 – 1.05 0.246 4428 44318 all phecode
327.4 Insomnia Neurological 1.04 0.888 – 1.22 0.609 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 0.994 0.833 – 1.19 0.947 136 1390 all phecode
331 Other cerebral degenerations Neurological 0.997 0.937 – 1.06 0.936 1142 11416 all phecode
331.1 Hydrocephalus Neurological 0.958 0.871 – 1.05 0.378 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 1.04 0.938 – 1.14 0.489 430 4298 all phecode
332 Parkinson's disease Neurological 1.02 0.957 – 1.08 0.562 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.06 0.993 – 1.14 0.08 894 8954 all phecode
333.1 Essential tremor Neurological 1.03 0.896 – 1.19 0.655 216 2157 all phecode
333.2 Myoclonus Neurological 1 0.813 – 1.24 0.965 96 958 all phecode
333.4 Torsion dystonia Neurological 1.06 0.934 – 1.21 0.354 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 1.01 0.96 – 1.06 0.764 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 1.04 0.866 – 1.25 0.668 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 1.05 0.926 – 1.2 0.426 245 2446 all phecode
335 Multiple sclerosis Neurological 0.98 0.925 – 1.04 0.482 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 0.97 0.854 – 1.1 0.64 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 0.98 0.767 – 1.25 0.871 72 719 all phecode
338 Pain Neurological 0.972 0.902 – 1.05 0.452 768 7692 all phecode
338.1 Acute pain Neurological 0.929 0.838 – 1.03 0.166 394 3937 all phecode
338.2 Chronic pain Neurological 0.986 0.888 – 1.09 0.79 380 3817 all phecode
339 Other headache syndromes Neurological 1.01 0.99 – 1.04 0.272 7819 78241 all phecode
340 Migraine Neurological 1 0.962 – 1.04 0.989 2860 28602 all phecode
340.1 Migrain with aura Neurological 0.965 0.833 – 1.12 0.631 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1 0.883 – 1.13 0.986 252 2535 all phecode
342 Hemiplegia Neurological 1 0.951 – 1.06 0.885 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 1.07 0.904 – 1.26 0.436 145 1450 all phecode
344 Other paralytic syndromes Neurological 1.02 0.936 – 1.1 0.713 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.02 0.995 – 1.05 0.108 5023 50270 all phecode
345.1 Epilepsy Neurological 1.01 0.944 – 1.09 0.729 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 1.06 0.963 – 1.17 0.235 439 4385 all phecode
345.12 Partial epilepsy Neurological 1.05 0.936 – 1.19 0.382 277 2776 all phecode
345.3 Convulsions Neurological 1.06 1.01 – 1.1 0.0156 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.881 0.74 – 1.05 0.156 144 1438 all phecode
348 Other conditions of brain Neurological 1.05 0.979 – 1.14 0.162 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.02 0.897 – 1.15 0.798 268 2678 all phecode
348.4 Cerebral cysts Neurological 0.946 0.792 – 1.13 0.538 133 1350 all phecode
348.7 Coma Neurological 1.09 0.977 – 1.22 0.121 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.14 1 – 1.3 0.0439 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 1.08 0.971 – 1.2 0.162 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.971 0.867 – 1.09 0.614 342 3414 all phecode
350 Abnormal movement Neurological 1.05 1 – 1.09 0.0294 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 1.05 0.975 – 1.12 0.21 887 8852 all phecode
350.2 Abnormality of gait Neurological 1.05 0.999 – 1.11 0.0546 1596 15969 all phecode
350.3 Lack of coordination Neurological 1.12 1.01 – 1.25 0.0381 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.977 0.738 – 1.29 0.87 54 540 all phecode
351 Other peripheral nerve disorders Neurological 1.02 1 – 1.04 0.0366 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 1.03 0.974 – 1.09 0.293 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1 0.911 – 1.11 0.941 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.07 0.994 – 1.14 0.0728 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 1 0.944 – 1.07 0.892 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 0.871 0.716 – 1.06 0.169 114 1138 all phecode
353.2 Nerve root lesions Neurological 1.03 0.789 – 1.35 0.812 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.02 0.86 – 1.2 0.848 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 0.95 0.897 – 1 0.073 1361 13648 all phecode
358 Myoneural disorders Neurological 1.07 0.931 – 1.23 0.339 211 2109 all phecode
358.1 Myasthenia gravis Neurological 1.07 0.921 – 1.23 0.394 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 1.07 0.975 – 1.18 0.147 465 4646 all phecode
359.1 Muscular dystrophies Neurological 1.02 0.845 – 1.22 0.862 122 1219 all phecode
359.2 Myopathy Neurological 1.09 0.974 – 1.21 0.139 360 3597 all phecode
360 Disorders of the globe Sense Organs 1.07 0.956 – 1.2 0.239 337 3367 all phecode
360.2 Progressive myopia Sense Organs 1.1 0.965 – 1.25 0.155 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 1 0.965 – 1.04 0.962 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.04 0.983 – 1.1 0.173 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.783 0.601 – 1.02 0.0688 68 680 all phecode
362 Other retinal disorders Sense Organs 1.01 0.973 – 1.04 0.711 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.01 0.966 – 1.06 0.647 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.01 0.967 – 1.06 0.609 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.984 0.833 – 1.16 0.851 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 1.01 0.824 – 1.25 0.898 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.987 0.918 – 1.06 0.721 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 1.02 0.873 – 1.19 0.8 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.02 0.813 – 1.29 0.837 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.948 0.781 – 1.15 0.588 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.12 0.959 – 1.3 0.154 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 1.05 0.826 – 1.33 0.709 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.989 0.911 – 1.07 0.783 647 6485 all phecode
364.1 Corneal opacity Sense Organs 1.14 0.918 – 1.42 0.235 90 910 all phecode
364.2 Corneal edema Sense Organs 0.913 0.725 – 1.15 0.436 79 800 all phecode
364.4 Corneal degenerations Sense Organs 0.976 0.84 – 1.13 0.75 201 2017 all phecode
364.41 Keratoconus Sense Organs 0.962 0.77 – 1.2 0.735 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 1.09 0.945 – 1.26 0.234 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 1.22 0.995 – 1.5 0.0558 100 1000 all phecode
365 Glaucoma Sense Organs 1.03 0.998 – 1.06 0.0704 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 1.09 1.03 – 1.17 0.00572 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.1 1.03 – 1.17 0.00427 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.994 0.919 – 1.08 0.89 698 6996 all phecode
366 Cataract Sense Organs 1.02 1.01 – 1.04 0.00137 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 1.08 0.852 – 1.38 0.511 69 700 all phecode
366.2 Senile cataract Sense Organs 1.03 1.01 – 1.05 0.0169 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 0.95 0.775 – 1.16 0.623 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.01 0.966 – 1.05 0.727 2408 24092 all phecode
367.1 Myopia Sense Organs 1.01 0.955 – 1.07 0.671 1251 12519 all phecode
367.2 Astigmatism Sense Organs 1.16 1.01 – 1.35 0.0389 190 1899 all phecode
367.8 Hypermetropia Sense Organs 1.02 0.899 – 1.17 0.715 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 0.99 0.916 – 1.07 0.803 719 7198 all phecode
368 Visual disturbances Sense Organs 1.02 0.986 – 1.06 0.22 2962 29648 all phecode
368.1 Amblyopia Sense Organs 1.12 1.03 – 1.22 0.0116 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.02 0.942 – 1.1 0.661 727 7288 all phecode
368.3 Anisometropia Sense Organs 1.05 0.889 – 1.24 0.558 154 1548 all phecode
368.4 Visual field defects Sense Organs 1.1 0.981 – 1.23 0.106 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 0.995 0.915 – 1.08 0.904 612 6115 all phecode
369 Infection of the eye Sense Organs 1.07 0.984 – 1.17 0.112 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 1.12 0.924 – 1.35 0.249 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 1.17 1.02 – 1.34 0.0292 213 2128 all phecode
370 Keratitis Sense Organs 0.961 0.849 – 1.09 0.536 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 0.972 0.816 – 1.16 0.756 141 1408 all phecode
371 Inflammation of the eye Sense Organs 0.942 0.907 – 0.979 0.0022 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.953 0.866 – 1.05 0.321 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 0.95 0.91 – 0.992 0.0204 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 0.947 0.877 – 1.02 0.162 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 1.06 1.03 – 1.09 3.3e-05 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 1.12 1.05 – 1.2 0.000326 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 1.06 1.01 – 1.11 0.0154 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 1.04 0.992 – 1.08 0.108 2204 22031 all phecode
375.2 Epiphora Sense Organs 1.04 0.973 – 1.12 0.24 898 8969 all phecode
376 Disorders of the orbit Sense Organs 1.1 0.877 – 1.38 0.414 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1 0.898 – 1.12 0.973 361 3618 all phecode
377.1 Optic atrophy Sense Organs 0.771 0.581 – 1.02 0.0713 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.954 0.791 – 1.15 0.626 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.06 1 – 1.12 0.0392 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.05 0.981 – 1.12 0.161 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.978 0.848 – 1.13 0.758 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 1.08 0.949 – 1.22 0.253 275 2755 all phecode
379 Other disorders of eye Sense Organs 1.01 0.976 – 1.05 0.552 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 0.991 0.936 – 1.05 0.754 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.05 0.997 – 1.1 0.0635 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 0.851 0.655 – 1.11 0.228 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.927 0.834 – 1.03 0.162 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.984 0.84 – 1.15 0.845 169 1690 all phecode
380 Disorders of external ear Sense Organs 1.01 0.932 – 1.1 0.77 642 6413 all phecode
380.1 Otitis externa Sense Organs 1.05 0.958 – 1.15 0.301 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 0.985 0.883 – 1.1 0.788 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.02 0.972 – 1.06 0.469 2150 21493 all phecode
381.1 Otitis media Sense Organs 1.03 0.976 – 1.08 0.32 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.02 0.948 – 1.09 0.644 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 0.97 0.835 – 1.13 0.684 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 0.957 0.814 – 1.13 0.596 171 1709 all phecode
381.9 Otorrhea Sense Organs 0.982 0.866 – 1.11 0.779 281 2807 all phecode
382 Otalgia Sense Organs 0.92 0.816 – 1.04 0.171 308 3084 all phecode
383 Otosclerosis Sense Organs 1.1 0.982 – 1.24 0.0971 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.01 0.957 – 1.07 0.648 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.01 0.952 – 1.08 0.676 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.05 0.972 – 1.13 0.227 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 1.08 0.993 – 1.17 0.0738 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.02 0.894 – 1.16 0.783 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.05 1 – 1.1 0.0477 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 1.09 0.998 – 1.18 0.0544 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 0.997 0.895 – 1.11 0.958 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 1.06 0.98 – 1.14 0.152 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.05 1.02 – 1.08 0.00181 4582 45806 all phecode
388 Other disorders of ear Sense Organs 1.06 0.913 – 1.22 0.469 202 2017 all phecode
389 Hearing loss Sense Organs 1.04 1.01 – 1.07 0.015 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 1 0.91 – 1.11 0.951 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 1.16 1.05 – 1.27 0.00316 450 4497 all phecode
389.4 Tinnitus Sense Organs 0.973 0.888 – 1.07 0.566 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.02 0.991 – 1.05 0.177 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 1 0.966 – 1.04 0.863 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 1.07 1.01 – 1.14 0.0183 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.03 0.969 – 1.1 0.32 1058 10566 all phecode
395 Heart valve disorders Circulatory System 1 0.972 – 1.04 0.841 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.993 0.955 – 1.03 0.729 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.979 0.867 – 1.11 0.732 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.16 0.953 – 1.42 0.137 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.92 0.744 – 1.14 0.444 97 970 all phecode
395.6 Heart valve replaced Circulatory System 1.05 0.998 – 1.11 0.0594 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 0.943 0.882 – 1.01 0.0793 1048 10468 all phecode
401 Hypertension Circulatory System 1.01 1 – 1.02 0.0025 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 1.01 1 – 1.02 0.00284 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.05 1 – 1.1 0.0315 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 0.992 0.892 – 1.1 0.883 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.07 1.01 – 1.12 0.0153 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 1.07 0.895 – 1.27 0.474 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.02 0.964 – 1.07 0.545 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 1.01 0.996 – 1.02 0.216 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.03 0.999 – 1.06 0.0576 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 1.01 0.99 – 1.03 0.369 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 1.02 1 – 1.04 0.0121 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.01 0.994 – 1.02 0.236 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.95 0.877 – 1.03 0.213 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.01 0.997 – 1.03 0.111 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.03 0.971 – 1.09 0.323 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 0.962 0.916 – 1.01 0.123 1823 18228 all phecode
414.2 ASCVD Circulatory System 0.842 0.648 – 1.09 0.198 72 719 all phecode
415 Pulmonary heart disease Circulatory System 1.02 0.993 – 1.06 0.128 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.958 0.761 – 1.21 0.719 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.03 0.948 – 1.12 0.473 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.03 0.936 – 1.14 0.52 448 4475 all phecode
416 Cardiomegaly Circulatory System 1.04 0.999 – 1.08 0.0556 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 1.01 0.999 – 1.02 0.0613 28599 270106 all phecode
418.1 Precordial pain Circulatory System 1.04 1.01 – 1.08 0.0217 3551 35541 all phecode
420 Carditis Circulatory System 1.04 0.998 – 1.09 0.0601 2106 21053 all phecode
420.1 Myocarditis Circulatory System 0.909 0.756 – 1.09 0.313 127 1267 all phecode
420.2 Pericarditis Circulatory System 1.04 0.981 – 1.1 0.2 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 1.16 1.01 – 1.33 0.0396 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 1.1 0.918 – 1.33 0.296 113 1129 all phecode
420.3 Endocarditis Circulatory System 1.06 0.98 – 1.14 0.145 719 7194 all phecode
425 Cardiomyopathy Circulatory System 0.99 0.933 – 1.05 0.732 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.988 0.93 – 1.05 0.683 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.945 0.79 – 1.13 0.537 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.88 0.748 – 1.04 0.127 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 1.03 0.795 – 1.34 0.81 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 1.03 1 – 1.06 0.0217 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.04 0.992 – 1.09 0.11 2114 21162 all phecode
426.21 First degree AV block Circulatory System 1.05 0.985 – 1.12 0.127 986 9867 all phecode
426.23 Second degree AV block Circulatory System 1.05 0.949 – 1.15 0.357 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.01 0.925 – 1.1 0.869 587 5868 all phecode
426.25 Other heart block Circulatory System 0.98 0.82 – 1.17 0.826 131 1318 all phecode
426.3 Bundle branch block Circulatory System 1.03 0.99 – 1.06 0.162 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 1.04 0.982 – 1.09 0.194 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 1.02 0.97 – 1.07 0.438 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.962 0.837 – 1.11 0.582 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.15 0.894 – 1.49 0.272 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.04 0.993 – 1.08 0.103 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.03 0.985 – 1.07 0.209 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 1.01 0.996 – 1.02 0.184 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 0.985 0.949 – 1.02 0.407 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.978 0.937 – 1.02 0.311 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.02 0.95 – 1.09 0.653 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.02 0.999 – 1.03 0.0579 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.993 0.957 – 1.03 0.695 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.04 0.98 – 1.11 0.191 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.989 0.886 – 1.11 0.848 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 1.03 0.966 – 1.1 0.348 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.987 0.923 – 1.06 0.715 952 9541 all phecode
427.6 Premature beats Circulatory System 1.04 0.947 – 1.13 0.446 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 0.998 0.817 – 1.22 0.985 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 1.01 0.97 – 1.06 0.552 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.05 0.947 – 1.16 0.366 402 4029 all phecode
427.9 Palpitations Circulatory System 1.04 1.01 – 1.08 0.0177 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.01 0.984 – 1.04 0.408 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.01 0.963 – 1.05 0.749 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 1.01 0.979 – 1.04 0.532 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.01 0.939 – 1.09 0.732 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 1.06 0.83 – 1.37 0.621 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.01 0.92 – 1.1 0.912 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.03 0.895 – 1.19 0.667 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 1.01 0.959 – 1.06 0.786 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.01 0.938 – 1.08 0.841 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1.02 0.948 – 1.1 0.562 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 0.862 0.757 – 0.981 0.0248 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 1.02 0.998 – 1.04 0.0687 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.06 0.995 – 1.12 0.0734 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.07 0.934 – 1.22 0.337 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.04 1.01 – 1.08 0.00784 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.06 1 – 1.11 0.0316 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 0.998 0.96 – 1.04 0.931 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.01 0.969 – 1.06 0.563 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 1 0.902 – 1.11 0.984 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.03 0.969 – 1.09 0.372 1279 12783 all phecode
440 Atherosclerosis Circulatory System 1 0.948 – 1.06 0.938 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.05 0.863 – 1.27 0.634 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.995 0.925 – 1.07 0.889 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 0.947 0.838 – 1.07 0.389 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.11 1.03 – 1.21 0.00913 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.05 0.932 – 1.18 0.426 283 2827 all phecode
442 Other aneurysm Circulatory System 1.03 0.978 – 1.08 0.301 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 1.05 0.992 – 1.1 0.0959 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.04 0.973 – 1.11 0.242 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 0.971 0.794 – 1.19 0.773 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.05 0.893 – 1.22 0.582 169 1696 all phecode
442.4 Arterial dissection Circulatory System 1.04 0.789 – 1.38 0.769 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 0.911 0.787 – 1.05 0.21 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 1.04 1 – 1.07 0.0338 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 1.06 0.996 – 1.13 0.0654 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.943 0.849 – 1.05 0.269 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.04 1.01 – 1.08 0.0113 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.04 1 – 1.08 0.0523 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.07 0.997 – 1.14 0.0598 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.05 0.961 – 1.14 0.291 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.965 0.897 – 1.04 0.334 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 0.905 0.777 – 1.06 0.203 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 0.985 0.886 – 1.1 0.786 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 0.987 0.864 – 1.13 0.841 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.03 0.97 – 1.09 0.364 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 1.06 0.989 – 1.14 0.101 868 8712 all phecode
448 Disease of capillaries Circulatory System 1.15 0.967 – 1.36 0.117 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.02 0.939 – 1.1 0.689 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.04 1 – 1.07 0.0379 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.03 0.998 – 1.07 0.0661 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.964 0.882 – 1.05 0.411 564 5645 all phecode
454 Varicose veins Circulatory System 0.985 0.966 – 1 0.133 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 0.985 0.966 – 1 0.117 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.974 0.896 – 1.06 0.538 624 6325 all phecode
455 Hemorrhoids Circulatory System 1.01 1 – 1.03 0.0363 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.936 0.805 – 1.09 0.387 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.953 0.778 – 1.17 0.641 97 967 all phecode
458 Hypotension Circulatory System 1.01 0.979 – 1.03 0.651 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 1.02 0.967 – 1.08 0.431 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.14 0.995 – 1.3 0.0601 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 1 0.969 – 1.04 0.814 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 1.03 1.01 – 1.05 0.000709 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 1.1 0.923 – 1.3 0.295 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 1.03 1.01 – 1.05 0.000755 16103 159422 all phecode
464 Acute sinusitis Respiratory 0.953 0.824 – 1.1 0.514 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.01 0.963 – 1.05 0.808 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 0.958 0.891 – 1.03 0.24 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.969 0.824 – 1.14 0.702 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1 0.973 – 1.03 0.825 4654 46553 all phecode
471 Nasal polyps Respiratory 1.04 1 – 1.08 0.0258 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.11 1.04 – 1.19 0.00158 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1.03 0.989 – 1.07 0.151 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 0.945 0.772 – 1.16 0.586 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.06 0.933 – 1.19 0.389 264 2647 all phecode
473.4 Voice disturbance Respiratory 1.08 1.01 – 1.15 0.0192 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 0.977 0.93 – 1.03 0.352 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 0.985 0.901 – 1.08 0.733 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.96 0.902 – 1.02 0.19 1122 11199 all phecode
475 Chronic sinusitis Respiratory 1.03 0.986 – 1.07 0.206 2589 25882 all phecode
476 Allergic rhinitis Respiratory 0.998 0.936 – 1.06 0.958 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 0.949 0.909 – 0.99 0.0149 2447 24452 all phecode
478 Throat pain Respiratory 1.01 0.91 – 1.13 0.792 377 3789 all phecode
479 Other upper respiratory disease Respiratory 1.02 0.986 – 1.05 0.281 4074 40737 all phecode
480 Pneumonia Respiratory 1.01 0.993 – 1.03 0.203 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 1.02 0.994 – 1.05 0.127 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.02 0.995 – 1.05 0.119 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 1 0.809 – 1.24 0.979 93 929 all phecode
480.2 Viral pneumonia Respiratory 1.11 0.871 – 1.41 0.4 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.999 0.815 – 1.23 0.995 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.949 0.882 – 1.02 0.162 794 7951 all phecode
481 Influenza Respiratory 1.01 0.903 – 1.13 0.843 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.06 0.915 – 1.24 0.421 193 1930 all phecode
495 Asthma Respiratory 1.01 1 – 1.03 0.0398 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 0.953 0.834 – 1.09 0.475 250 2510 all phecode
496 Chronic airway obstruction Respiratory 1.03 1.01 – 1.05 0.00596 10424 101546 all phecode
496.1 Emphysema Respiratory 1.02 0.973 – 1.07 0.377 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 1.02 0.98 – 1.06 0.351 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.02 0.976 – 1.06 0.439 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 1.03 0.985 – 1.08 0.176 1885 18859 all phecode
497 Bronchitis Respiratory 0.943 0.866 – 1.03 0.17 626 6267 all phecode
500 Lung disease due to external agents Respiratory 1.06 0.958 – 1.17 0.257 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.26 1.01 – 1.57 0.0403 79 784 all phecode
500.2 Pneumoconiosis Respiratory 1.04 0.913 – 1.19 0.543 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.11 1.03 – 1.2 0.0078 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.01 0.947 – 1.08 0.703 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.03 0.937 – 1.12 0.591 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.06 0.95 – 1.19 0.285 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 0.948 0.719 – 1.25 0.708 61 610 all phecode
506 Empyema and pneumothorax Respiratory 1 0.941 – 1.07 0.967 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 1.02 0.992 – 1.04 0.168 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.01 0.968 – 1.06 0.548 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.03 0.993 – 1.08 0.103 2599 26031 all phecode
509.1 Respiratory failure Respiratory 1.04 0.991 – 1.09 0.113 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 1.02 0.976 – 1.08 0.333 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 0.965 0.814 – 1.14 0.679 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.1 0.994 – 1.23 0.0649 386 3863 all phecode
510 Other diseases of lung Respiratory 1.07 0.992 – 1.15 0.0796 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 1.03 1.01 – 1.06 0.00196 9031 90349 all phecode
512.1 Wheezing Respiratory 1.09 0.951 – 1.24 0.218 220 2196 all phecode
512.2 Painful respiration Respiratory 0.948 0.823 – 1.09 0.455 207 2075 all phecode
512.7 Shortness of breath Respiratory 1.04 1.01 – 1.07 0.00481 5842 58498 all phecode
512.8 Cough Respiratory 1.05 1.01 – 1.09 0.0142 2866 28642 all phecode
512.9 Other dyspnea Respiratory 1.05 0.984 – 1.13 0.136 914 9124 all phecode
513 Respiratory abnormalities Respiratory 1.05 0.967 – 1.14 0.24 611 6112 all phecode
513.3 Hypoventilation Respiratory 0.977 0.783 – 1.22 0.837 83 830 all phecode
513.4 Hyperventilation Respiratory 0.989 0.873 – 1.12 0.861 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 1 0.845 – 1.19 0.97 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 1.03 0.988 – 1.07 0.161 2465 24673 all phecode
516 Abnormal sputum Respiratory 0.996 0.952 – 1.04 0.851 2132 21335 all phecode
516.1 Hemoptysis Respiratory 1.01 0.967 – 1.06 0.603 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.03 1.01 – 1.05 0.00514 9366 93681 all phecode
519.2 Respiratory complications Respiratory 1.08 0.966 – 1.21 0.179 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.03 1.01 – 1.06 0.00315 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.986 0.876 – 1.11 0.815 303 3049 all phecode
520 Disorders of tooth development Digestive 1.01 0.96 – 1.05 0.802 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.97 0.72 – 1.31 0.843 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 1.03 0.992 – 1.08 0.115 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 1.01 0.968 – 1.04 0.78 3016 30245 all phecode
521.1 Dental caries Digestive 1.01 0.97 – 1.05 0.701 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 0.941 0.895 – 0.989 0.0172 1774 17750 all phecode
522.5 Periapical abscess Digestive 0.933 0.877 – 0.992 0.0269 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 0.996 0.947 – 1.05 0.87 1681 16812 all phecode
523.1 Gingivitis Digestive 1.02 0.838 – 1.24 0.846 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.01 0.954 – 1.08 0.681 1165 11650 all phecode
523.31 Acute periodontitis Digestive 1.05 0.967 – 1.14 0.249 666 6667 all phecode
523.32 Chronic periodontitis Digestive 0.971 0.891 – 1.06 0.506 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.02 0.912 – 1.15 0.683 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.02 0.907 – 1.16 0.704 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.994 0.954 – 1.03 0.761 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.884 0.689 – 1.14 0.334 72 720 all phecode
526 Diseases of the jaws Digestive 0.965 0.901 – 1.03 0.305 928 9279 all phecode
526.1 Cysts of the jaws Digestive 0.986 0.88 – 1.11 0.814 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.876 0.674 – 1.14 0.324 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.02 0.893 – 1.16 0.801 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.01 0.88 – 1.15 0.94 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.946 0.771 – 1.16 0.594 110 1098 all phecode
526.9 Jaw disease NOS Digestive 0.937 0.818 – 1.07 0.347 233 2329 all phecode
527 Diseases of the salivary glands Digestive 0.986 0.912 – 1.07 0.727 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 0.908 0.724 – 1.14 0.403 84 838 all phecode
527.2 Sialoadenitis Digestive 0.97 0.869 – 1.08 0.588 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 1.16 0.909 – 1.49 0.231 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.05 0.876 – 1.27 0.581 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.03 0.999 – 1.07 0.0554 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 1.19 1.09 – 1.31 0.000205 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.2 1.09 – 1.33 0.000297 389 3884 all phecode
528.12 Oral aphthae Digestive 1.05 0.842 – 1.32 0.643 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.968 0.828 – 1.13 0.683 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 0.897 0.739 – 1.09 0.273 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 0.855 0.686 – 1.07 0.165 94 940 all phecode
528.5 Diseases of lips Digestive 1.04 0.957 – 1.12 0.39 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.01 0.897 – 1.14 0.873 308 3079 all phecode
528.7 Sialolithiasis Digestive 1.05 0.934 – 1.18 0.424 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 0.977 0.921 – 1.04 0.445 1232 12312 all phecode
529.1 Glossitis Digestive 0.92 0.815 – 1.04 0.178 299 2986 all phecode
530 Diseases of esophagus Digestive 1.02 1.01 – 1.03 0.00151 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.02 1.01 – 1.03 0.00127 31253 272429 all phecode
530.11 GERD Digestive 1.01 0.999 – 1.03 0.0649 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 1.05 1.02 – 1.08 0.00181 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 1.01 0.99 – 1.03 0.314 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.02 0.972 – 1.08 0.396 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.01 0.96 – 1.06 0.778 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 0.982 0.904 – 1.07 0.669 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.11 0.944 – 1.31 0.204 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.07 0.957 – 1.19 0.237 341 3416 all phecode
530.9 Heartburn Digestive 1.05 1 – 1.1 0.04 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.01 0.986 – 1.04 0.425 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.02 0.938 – 1.1 0.672 637 6374 all phecode
531.2 Gastric ulcer Digestive 1.01 0.976 – 1.04 0.621 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 0.993 0.956 – 1.03 0.728 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.12 1.02 – 1.23 0.0235 427 4268 all phecode
532 Dysphagia Digestive 1.04 1.02 – 1.07 0.000857 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 1.03 1.02 – 1.05 1.5e-07 28078 261548 all phecode
535.1 Acute gastritis Digestive 0.988 0.93 – 1.05 0.682 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 1.09 0.982 – 1.21 0.106 370 3687 all phecode
535.6 Duodenitis Digestive 1.03 1 – 1.05 0.0213 7592 75928 all phecode
535.8 Other specified gastritis Digestive 1.03 1.01 – 1.06 0.0045 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.05 0.883 – 1.25 0.568 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.05 0.931 – 1.19 0.415 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 1.05 1.01 – 1.09 0.00608 3391 33907 all phecode
540 Appendiceal conditions Digestive 0.972 0.936 – 1.01 0.133 3088 30890 all phecode
540.1 Appendicitis Digestive 0.969 0.932 – 1.01 0.108 2895 28963 all phecode
540.11 Acute appendicitis Digestive 0.971 0.932 – 1.01 0.151 2601 26019 all phecode
550 Abdominal hernia Digestive 1.01 1 – 1.02 0.0049 45429 282640 all phecode
550.1 Inguinal hernia Digestive 1.01 0.99 – 1.02 0.464 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 1.02 1.01 – 1.04 0.000161 26494 238953 all phecode
550.3 Femoral hernia Digestive 1 0.926 – 1.09 0.924 651 6504 all phecode
550.4 Umbilical hernia Digestive 1.01 0.979 – 1.05 0.466 3705 37072 all phecode
550.5 Ventral hernia Digestive 1.04 1 – 1.08 0.0339 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.02 0.991 – 1.05 0.171 4444 44442 all phecode
555.1 Regional enteritis Digestive 0.998 0.949 – 1.05 0.941 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 1.04 1 – 1.08 0.0476 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 0.997 0.912 – 1.09 0.946 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 1.07 1.01 – 1.14 0.0295 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 1.06 0.98 – 1.15 0.145 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.964 0.854 – 1.09 0.548 299 2987 all phecode
557.1 Celiac disease Digestive 1.13 1.08 – 1.19 5.17e-07 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 1.03 1.01 – 1.05 0.000436 15492 155105 all phecode
559 Ileostomy status Digestive 1.03 0.978 – 1.08 0.277 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.04 1 – 1.07 0.0355 3936 39337 all phecode
560.1 Paralytic ileus Digestive 1.12 1.03 – 1.23 0.0123 523 5231 all phecode
560.2 Impaction of intestine Digestive 1.03 0.911 – 1.17 0.624 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.06 0.991 – 1.14 0.085 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 1.03 0.99 – 1.06 0.159 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 1 0.988 – 1.02 0.592 15772 157686 all phecode
561.1 Diarrhea Digestive 1.1 1 – 1.2 0.0499 466 4653 all phecode
561.2 Flatulence Digestive 1.02 0.973 – 1.08 0.372 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 1.01 1 – 1.03 0.0426 26714 211692 all phecode
562.1 Diverticulosis Digestive 1.01 1 – 1.03 0.0422 26672 211642 all phecode
563 Constipation Digestive 1 0.981 – 1.02 0.89 10314 103140 all phecode
564 Functional digestive disorders Digestive 1.02 1 – 1.03 0.0176 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.02 0.991 – 1.05 0.187 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1 0.953 – 1.06 0.882 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 1.02 1.01 – 1.04 0.00441 15186 151648 all phecode
565 Anal and rectal conditions Digestive 1.02 1 – 1.04 0.0239 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 1.03 1.01 – 1.06 0.0103 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.01 0.943 – 1.08 0.77 929 9293 all phecode
568 Other disorders of peritoneum Digestive 1.02 0.983 – 1.06 0.294 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.02 0.979 – 1.05 0.405 3101 30987 all phecode
569 Other disorders of intestine Digestive 1.01 0.983 – 1.05 0.377 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.06 0.896 – 1.26 0.482 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 0.928 0.845 – 1.02 0.124 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.07 1.03 – 1.11 0.000549 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.05 0.995 – 1.1 0.0788 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.839 0.689 – 1.02 0.082 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 1.14 1.01 – 1.3 0.0364 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.07 1 – 1.14 0.046 976 9804 all phecode
571.81 Portal hypertension Digestive 1.08 0.992 – 1.19 0.0754 528 5285 all phecode
572 Ascites (non malignant) Digestive 1.05 0.994 – 1.1 0.0807 1544 15454 all phecode
573 Other disorders of liver Digestive 1.04 0.982 – 1.09 0.198 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 1.04 0.844 – 1.28 0.725 96 960 all phecode
573.3 Hepatomegaly Digestive 1.04 0.926 – 1.18 0.478 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 1.04 0.969 – 1.11 0.291 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 1.04 1 – 1.07 0.0499 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.17 1.01 – 1.35 0.0304 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.02 1 – 1.03 0.054 15607 156123 all phecode
574.1 Cholelithiasis Digestive 1.02 0.999 – 1.04 0.0634 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.06 1.01 – 1.12 0.0305 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.02 0.988 – 1.05 0.251 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 0.995 0.955 – 1.04 0.795 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.01 0.973 – 1.05 0.546 2748 27523 all phecode
575 Other biliary tract disease Digestive 1.04 1 – 1.07 0.0292 3867 38724 all phecode
575.1 Cholangitis Digestive 1 0.915 – 1.1 0.924 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 1.01 0.936 – 1.09 0.814 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 1.09 0.991 – 1.2 0.0773 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 1.09 1.04 – 1.15 0.00101 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 1 0.939 – 1.07 0.976 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.931 0.832 – 1.04 0.214 348 3488 all phecode
577 Diseases of pancreas Digestive 1.05 1 – 1.09 0.0309 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 1.05 0.998 – 1.1 0.0587 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 1.02 0.93 – 1.12 0.694 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.01 0.91 – 1.13 0.8 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 1.02 1.01 – 1.04 0.00293 20626 206278 all phecode
578.1 Hematemesis Digestive 1.06 1.01 – 1.11 0.0122 1958 19564 all phecode
578.2 Blood in stool Digestive 1.03 0.987 – 1.07 0.179 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.03 1.01 – 1.05 0.00202 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.01 0.981 – 1.04 0.506 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.03 0.979 – 1.09 0.239 1548 15498 all phecode
579.2 Splenomegaly Digestive 1.03 0.932 – 1.14 0.548 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.03 0.975 – 1.08 0.329 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.06 1.01 – 1.12 0.0194 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 1.05 0.986 – 1.12 0.127 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.17 0.932 – 1.47 0.175 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.11 0.935 – 1.33 0.226 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.03 0.956 – 1.1 0.483 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.12 1.02 – 1.23 0.0222 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.1 0.968 – 1.26 0.139 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.12 0.979 – 1.27 0.101 253 2529 all phecode
585 Renal failure Genitourinary 1.02 0.995 – 1.05 0.118 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 1.01 0.976 – 1.04 0.653 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 1.02 0.971 – 1.08 0.374 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.02 0.985 – 1.07 0.229 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 1.1 1 – 1.2 0.0508 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.02 0.982 – 1.05 0.343 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.989 0.858 – 1.14 0.878 208 2089 all phecode
586.11 Small kidney Genitourinary 0.973 0.834 – 1.14 0.73 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 0.982 0.926 – 1.04 0.547 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.03 0.823 – 1.28 0.808 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.02 0.952 – 1.09 0.585 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 1.12 1 – 1.24 0.0402 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.1 0.899 – 1.35 0.35 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 0.9 0.741 – 1.09 0.292 116 1158 all phecode
590 Pyelonephritis Genitourinary 1.03 0.969 – 1.08 0.389 1328 13285 all phecode
591 Urinary tract infection Genitourinary 1.01 0.992 – 1.03 0.273 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 1.04 1 – 1.08 0.0448 2966 29661 all phecode
592.1 Cystitis Genitourinary 1.04 1 – 1.08 0.035 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 1.05 0.889 – 1.25 0.545 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 1.04 0.972 – 1.12 0.248 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 1.02 0.899 – 1.17 0.728 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.924 0.788 – 1.08 0.328 165 1662 all phecode
593 Hematuria Genitourinary 1.02 1 – 1.04 0.0302 16068 160204 all phecode
594 Urinary calculus Genitourinary 1.01 0.988 – 1.04 0.308 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 1.02 0.984 – 1.06 0.269 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.03 0.956 – 1.11 0.438 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 1.02 0.974 – 1.06 0.459 2401 24024 all phecode
594.8 Renal colic Genitourinary 1.01 0.96 – 1.05 0.827 2050 20500 all phecode
595 Hydronephrosis Genitourinary 1 0.955 – 1.05 0.964 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 1.01 0.985 – 1.03 0.594 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 1.02 0.973 – 1.07 0.415 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 1.05 0.996 – 1.1 0.0742 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.993 0.96 – 1.03 0.672 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.995 0.959 – 1.03 0.766 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 0.977 0.768 – 1.24 0.849 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.02 0.989 – 1.06 0.18 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.09 0.965 – 1.22 0.172 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1 0.987 – 1.02 0.795 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 0.915 0.779 – 1.07 0.279 166 1670 all phecode
599.2 Retention of urine Genitourinary 1.01 0.982 – 1.03 0.577 6718 67168 all phecode
599.3 Dysuria Genitourinary 1.05 0.989 – 1.11 0.111 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 1 0.978 – 1.02 0.976 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 0.995 0.962 – 1.03 0.744 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 1.09 0.895 – 1.34 0.377 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.03 0.804 – 1.33 0.801 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 1.03 0.986 – 1.09 0.162 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 0.992 0.973 – 1.01 0.453 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.968 0.925 – 1.01 0.168 2081 20818 all phecode
601.1 Prostatitis Genitourinary 0.999 0.948 – 1.05 0.983 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 0.967 0.846 – 1.11 0.628 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 1.01 0.939 – 1.08 0.88 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.19 0.922 – 1.55 0.178 59 588 all phecode
601.4 Balanoposthitis Genitourinary 0.882 0.777 – 1 0.0513 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.932 0.826 – 1.05 0.249 303 3019 all phecode
602 Other disorders of prostate Genitourinary 0.934 0.882 – 0.989 0.0189 1341 13408 all phecode
603 Other disorders of testis Genitourinary 1.01 0.963 – 1.05 0.759 2150 21512 all phecode
603.1 Hydrocele Genitourinary 0.978 0.924 – 1.04 0.454 1339 13402 all phecode
604 Disorders of penis Genitourinary 0.974 0.939 – 1.01 0.153 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.972 0.934 – 1.01 0.17 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.03 0.916 – 1.17 0.592 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 1.02 0.981 – 1.06 0.311 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.922 0.796 – 1.07 0.277 214 2138 all phecode
609.1 Infertility, male Genitourinary 0.931 0.727 – 1.19 0.569 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.927 0.783 – 1.1 0.374 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 1.02 0.975 – 1.06 0.456 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 1.12 1.05 – 1.2 0.000653 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 0.994 0.883 – 1.12 0.921 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 0.955 0.843 – 1.08 0.469 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 1.02 0.963 – 1.08 0.519 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1 0.928 – 1.09 0.923 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.991 0.94 – 1.04 0.731 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 1.07 0.817 – 1.4 0.624 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 0.987 0.935 – 1.04 0.632 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.96 0.895 – 1.03 0.246 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.987 0.92 – 1.06 0.716 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 0.805 0.632 – 1.02 0.0783 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 1.06 1 – 1.11 0.0316 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.07 0.996 – 1.16 0.0633 720 7210 all phecode
613.5 Mastodynia Genitourinary 1.07 0.849 – 1.34 0.579 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 1.12 1.04 – 1.21 0.00346 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 1.05 0.936 – 1.18 0.41 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 1.02 0.886 – 1.17 0.797 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.03 0.999 – 1.06 0.0583 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.03 0.99 – 1.08 0.133 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.04 0.966 – 1.12 0.302 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.1 0.846 – 1.42 0.483 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.06 0.961 – 1.18 0.235 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.08 0.966 – 1.21 0.177 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.966 0.849 – 1.1 0.604 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.03 0.985 – 1.07 0.228 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.04 0.982 – 1.1 0.183 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.994 0.901 – 1.1 0.912 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.989 0.917 – 1.07 0.768 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.08 0.956 – 1.22 0.214 274 2737 all phecode
615 Endometriosis Genitourinary 1.01 0.975 – 1.04 0.675 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.08 0.957 – 1.21 0.219 304 3037 all phecode
618 Genital prolapse Genitourinary 0.996 0.977 – 1.02 0.698 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1.02 0.991 – 1.04 0.214 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.967 0.939 – 0.995 0.0204 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.04 0.945 – 1.14 0.441 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.04 0.957 – 1.13 0.369 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 1.02 0.997 – 1.04 0.0923 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.973 0.901 – 1.05 0.493 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1.02 0.979 – 1.05 0.419 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.03 0.993 – 1.07 0.113 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1 0.955 – 1.05 0.906 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.05 0.995 – 1.11 0.0752 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 0.949 0.749 – 1.2 0.668 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 1.02 0.959 – 1.08 0.53 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 1.01 0.992 – 1.03 0.255 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 1.01 0.983 – 1.03 0.594 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 1.05 1.01 – 1.09 0.00786 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.01 0.952 – 1.07 0.751 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 1.03 0.962 – 1.11 0.369 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.966 0.845 – 1.1 0.613 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 1.06 0.964 – 1.18 0.217 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 0.994 0.967 – 1.02 0.639 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.04 1 – 1.08 0.0508 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 1.05 0.993 – 1.12 0.0842 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.01 0.991 – 1.02 0.379 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1 0.984 – 1.02 0.865 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 1.09 0.898 – 1.32 0.383 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.02 0.998 – 1.04 0.0802 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 1.01 0.966 – 1.06 0.608 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.979 0.946 – 1.01 0.219 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 0.998 0.951 – 1.05 0.936 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 1.02 0.869 – 1.21 0.781 159 1587 all phecode
626.8 Infertility, female Genitourinary 1.08 1.02 – 1.14 0.00805 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.01 0.987 – 1.03 0.478 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 1.01 0.993 – 1.04 0.182 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 0.898 0.769 – 1.05 0.178 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.975 0.915 – 1.04 0.419 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.941 0.836 – 1.06 0.317 310 3097 all phecode
628 Ovarian cyst Genitourinary 1.03 1 – 1.07 0.0324 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.01 0.983 – 1.04 0.394 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.06 0.994 – 1.12 0.0749 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.06 0.945 – 1.18 0.337 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.01 0.96 – 1.05 0.795 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.986 0.919 – 1.06 0.696 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.03 0.969 – 1.09 0.363 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1 0.958 – 1.04 0.99 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.977 0.899 – 1.06 0.59 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.05 0.987 – 1.12 0.125 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 0.965 0.76 – 1.22 0.766 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.97 0.911 – 1.03 0.343 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.01 0.897 – 1.14 0.874 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.29 1.12 – 1.48 0.000287 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.19 1.02 – 1.4 0.0289 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.05 0.988 – 1.11 0.124 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.983 0.94 – 1.03 0.447 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.764 0.589 – 0.99 0.0416 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.867 0.762 – 0.986 0.0292 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.973 0.802 – 1.18 0.784 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.03 0.893 – 1.2 0.656 193 1922 all phecode
650 Normal delivery Pregnancy Complications 1 0.956 – 1.05 0.916 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 0.997 0.892 – 1.11 0.958 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1.01 0.964 – 1.07 0.587 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.989 0.935 – 1.05 0.697 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.11 0.883 – 1.4 0.367 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.984 0.952 – 1.02 0.326 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.941 0.769 – 1.15 0.553 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.985 0.942 – 1.03 0.501 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.99 0.905 – 1.08 0.834 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.965 0.936 – 0.994 0.0203 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.99 0.95 – 1.03 0.649 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.01 0.854 – 1.19 0.936 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.922 0.811 – 1.05 0.216 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.996 0.769 – 1.29 0.977 63 624 all phecode
679 Complications of in utero procedures Dermatologic 1.23 0.94 – 1.61 0.13 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.04 1.01 – 1.07 0.00184 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.04 0.957 – 1.14 0.345 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.06 0.966 – 1.16 0.223 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.04 1.01 – 1.07 0.0112 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.04 1.01 – 1.07 0.00994 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.04 1.01 – 1.07 0.00846 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.09 1 – 1.19 0.0419 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.14 1.08 – 1.2 4.1e-06 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.04 1 – 1.09 0.0495 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 0.984 0.904 – 1.07 0.715 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 1.09 0.98 – 1.21 0.111 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1.04 0.954 – 1.14 0.359 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.05 1 – 1.09 0.0523 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 0.98 0.866 – 1.11 0.753 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 1.06 0.875 – 1.29 0.538 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.02 0.986 – 1.06 0.22 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.1 1.07 – 1.13 8.1e-13 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 1.12 0.885 – 1.41 0.351 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 1.15 0.878 – 1.51 0.31 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 1.21 1.01 – 1.46 0.0373 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 1.13 1.06 – 1.2 0.000292 986 9854 all phecode
694.1 Vitiligo Dermatologic 0.848 0.641 – 1.12 0.248 60 599 all phecode
694.2 Other dyschromia Dermatologic 1.17 1.08 – 1.25 3.65e-05 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 1.13 0.938 – 1.37 0.196 117 1170 all phecode
695 Erythematous conditions Dermatologic 1.05 1.01 – 1.1 0.0158 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 1.08 0.89 – 1.31 0.444 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 1.11 0.935 – 1.31 0.237 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 1.1 0.851 – 1.42 0.472 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.13 0.889 – 1.43 0.326 73 727 all phecode
695.3 Rosacea Dermatologic 1.11 0.988 – 1.24 0.0792 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.11 1.01 – 1.23 0.0337 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.17 0.983 – 1.4 0.0776 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.08 0.974 – 1.21 0.139 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 0.99 0.918 – 1.07 0.788 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 1.14 1 – 1.3 0.0501 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 0.937 0.742 – 1.18 0.581 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.04 0.945 – 1.14 0.424 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 0.975 0.933 – 1.02 0.257 2252 22509 all phecode
696.4 Psoriasis Dermatologic 0.979 0.936 – 1.02 0.346 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 0.983 0.934 – 1.03 0.503 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 0.998 0.923 – 1.08 0.961 706 7052 all phecode
697 Sarcoidosis Dermatologic 0.948 0.868 – 1.04 0.239 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 1.06 0.981 – 1.14 0.149 782 7814 all phecode
700 Corns and callosities Dermatologic 0.988 0.874 – 1.12 0.85 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.1 1.07 – 1.13 4.45e-10 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 1.03 0.822 – 1.29 0.808 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.14 1.09 – 1.19 1.9e-09 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.17 0.916 – 1.51 0.204 61 610 all phecode
701.4 Keloid scar Dermatologic 1.13 0.98 – 1.3 0.093 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.04 0.942 – 1.15 0.443 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.2 0.974 – 1.47 0.0882 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.19 1.16 – 1.23 1.23e-35 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 1.34 1.29 – 1.4 7.8e-48 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 1.09 1.05 – 1.13 3.22e-06 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 1 0.899 – 1.12 0.976 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 1.05 0.981 – 1.12 0.16 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 1.06 1.03 – 1.09 6.25e-05 5267 52727 all phecode
704.1 Alopecia Dermatologic 0.941 0.782 – 1.13 0.517 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.13 0.899 – 1.43 0.293 76 759 all phecode
705 Disorders of sweat glands Dermatologic 0.998 0.871 – 1.14 0.981 228 2287 all phecode
705.3 Hidradenitis Dermatologic 0.967 0.831 – 1.12 0.66 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 1 0.92 – 1.09 0.972 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 1.06 1.04 – 1.09 2.42e-07 8317 83195 all phecode
706.1 Acne Dermatologic 0.908 0.714 – 1.16 0.433 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 1.06 1.04 – 1.09 4.84e-08 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 1.04 0.996 – 1.09 0.0757 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 1.04 0.967 – 1.11 0.314 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.997 0.962 – 1.03 0.874 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 1.05 0.96 – 1.15 0.272 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 1.12 0.958 – 1.3 0.157 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.2 0.934 – 1.53 0.156 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.989 0.95 – 1.03 0.58 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.07 0.986 – 1.17 0.103 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 1.08 0.994 – 1.18 0.0674 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.01 0.872 – 1.17 0.906 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.11 1.01 – 1.23 0.0383 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.01 0.914 – 1.12 0.809 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.06 0.943 – 1.19 0.335 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.07 0.858 – 1.34 0.545 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.921 0.776 – 1.09 0.343 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 0.909 0.711 – 1.16 0.445 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.02 0.994 – 1.05 0.119 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.03 0.997 – 1.06 0.076 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.02 0.97 – 1.07 0.437 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.11 0.913 – 1.35 0.291 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.963 0.886 – 1.05 0.377 618 6177 all phecode
716 Other arthropathies Musculoskeletal 1.01 0.995 – 1.02 0.263 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.04 1 – 1.08 0.0254 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.01 0.994 – 1.03 0.228 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.01 0.996 – 1.02 0.217 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.991 0.932 – 1.05 0.759 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 0.994 0.961 – 1.03 0.745 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1.03 1 – 1.05 0.0368 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.03 1 – 1.06 0.0296 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.03 0.887 – 1.2 0.689 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.12 1 – 1.24 0.0468 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 1 0.979 – 1.02 0.923 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.12 1.03 – 1.23 0.0112 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1 0.964 – 1.04 0.914 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.06 0.818 – 1.38 0.648 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.99 0.959 – 1.02 0.538 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 0.907 0.827 – 0.995 0.0385 517 5173 all phecode
723.1 Torticollis Musculoskeletal 0.993 0.814 – 1.21 0.945 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.03 0.983 – 1.08 0.227 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.04 0.938 – 1.15 0.457 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 1.03 0.928 – 1.14 0.604 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.13 0.88 – 1.44 0.342 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.03 0.974 – 1.08 0.335 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.01 0.988 – 1.02 0.555 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 1.02 0.994 – 1.04 0.165 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 0.913 0.815 – 1.02 0.114 334 3336 all phecode
726.3 Bursitis Musculoskeletal 0.978 0.911 – 1.05 0.551 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1 0.977 – 1.03 0.931 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.01 0.974 – 1.05 0.525 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 1.02 0.835 – 1.24 0.862 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.98 0.943 – 1.02 0.281 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 1.02 0.938 – 1.11 0.619 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.985 0.881 – 1.1 0.787 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.05 0.89 – 1.25 0.541 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.03 0.993 – 1.06 0.115 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.979 0.883 – 1.09 0.688 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 1.03 1 – 1.07 0.0494 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.03 0.997 – 1.07 0.073 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 0.996 0.97 – 1.02 0.764 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1 0.939 – 1.07 0.96 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 0.951 0.777 – 1.17 0.63 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.924 0.816 – 1.05 0.217 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.943 0.83 – 1.07 0.372 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 0.902 0.819 – 0.994 0.0374 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.846 0.73 – 0.98 0.0257 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.91 0.698 – 1.19 0.486 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.998 0.95 – 1.05 0.94 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 0.941 0.836 – 1.06 0.321 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.987 0.902 – 1.08 0.769 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 1.06 0.882 – 1.28 0.522 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.988 0.931 – 1.05 0.692 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 1.02 0.846 – 1.24 0.814 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 1 0.983 – 1.03 0.74 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 0.949 0.813 – 1.11 0.502 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 1.02 0.987 – 1.05 0.268 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.01 0.959 – 1.05 0.829 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 1.04 0.99 – 1.1 0.115 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.999 0.974 – 1.02 0.937 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.971 0.922 – 1.02 0.258 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.09 0.959 – 1.25 0.18 248 2476 all phecode
737 Curvature of spine Musculoskeletal 1.06 1 – 1.13 0.0443 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.04 0.981 – 1.11 0.175 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.984 0.938 – 1.03 0.515 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1 0.949 – 1.06 0.959 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 1.08 0.983 – 1.18 0.11 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 1.01 1 – 1.03 0.0451 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.01 0.995 – 1.03 0.185 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.02 0.996 – 1.04 0.114 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.08 0.961 – 1.2 0.205 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.11 1.02 – 1.21 0.0137 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.02 1 – 1.04 0.0173 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.997 0.963 – 1.03 0.862 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 1.13 0.928 – 1.38 0.222 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 0.972 0.893 – 1.06 0.501 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 1.02 0.857 – 1.2 0.858 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 1.01 0.952 – 1.06 0.837 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 0.891 0.729 – 1.09 0.261 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 0.945 0.707 – 1.26 0.704 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.01 0.971 – 1.05 0.622 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 0.918 0.819 – 1.03 0.139 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.991 0.807 – 1.22 0.931 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 0.959 0.875 – 1.05 0.37 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 1.03 0.983 – 1.08 0.223 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.02 0.994 – 1.04 0.14 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 1.02 0.996 – 1.05 0.105 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 1.01 0.986 – 1.04 0.336 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1.02 0.93 – 1.11 0.721 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 1.03 0.942 – 1.13 0.511 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.991 0.921 – 1.07 0.807 815 8144 all phecode
745 Pain in joint Musculoskeletal 1.01 0.986 – 1.03 0.444 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.987 0.949 – 1.03 0.529 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.985 0.945 – 1.03 0.454 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1 0.918 – 1.09 0.98 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.06 0.926 – 1.21 0.399 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.965 0.919 – 1.01 0.151 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.02 0.868 – 1.2 0.804 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.02 0.766 – 1.37 0.877 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.974 0.865 – 1.1 0.67 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 1.07 0.986 – 1.15 0.109 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.984 0.877 – 1.1 0.786 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.993 0.855 – 1.15 0.926 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.12 1.01 – 1.25 0.0326 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.12 0.976 – 1.28 0.109 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.17 0.97 – 1.41 0.1 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.05 0.993 – 1.1 0.0898 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.01 0.934 – 1.09 0.795 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.03 0.937 – 1.14 0.506 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.976 0.851 – 1.12 0.73 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.07 0.996 – 1.15 0.0652 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 1.1 0.999 – 1.22 0.0531 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.03 0.915 – 1.15 0.667 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.992 0.886 – 1.11 0.89 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 1.01 0.892 – 1.15 0.825 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 1.06 0.923 – 1.22 0.397 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.01 0.799 – 1.27 0.943 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.827 0.682 – 1 0.0527 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.878 0.683 – 1.13 0.313 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.05 0.859 – 1.27 0.654 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.03 0.937 – 1.14 0.501 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.05 0.914 – 1.21 0.49 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.02 0.866 – 1.2 0.822 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.92 0.752 – 1.12 0.413 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.05 0.963 – 1.14 0.276 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.03 0.828 – 1.29 0.765 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.03 0.931 – 1.14 0.574 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.991 0.83 – 1.18 0.921 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.918 0.699 – 1.21 0.542 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.09 0.948 – 1.25 0.233 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.976 0.791 – 1.2 0.821 96 959 all phecode
760 Back pain Symptoms 1.01 0.987 – 1.03 0.496 11126 111353 all phecode
761 Cervicalgia Symptoms 0.992 0.945 – 1.04 0.754 1791 17901 all phecode
764 Sciatica Symptoms 0.973 0.932 – 1.02 0.207 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.975 0.917 – 1.04 0.422 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 1.07 0.983 – 1.16 0.119 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.996 0.928 – 1.07 0.905 870 8687 all phecode
771.1 Swelling of limb Symptoms 0.992 0.962 – 1.02 0.586 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 1.06 0.982 – 1.15 0.132 659 6581 all phecode
773 Pain in limb Symptoms 1.02 0.991 – 1.04 0.198 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 1.04 0.886 – 1.22 0.629 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.973 0.927 – 1.02 0.277 1870 18715 all phecode
782.3 Edema Symptoms 1.05 1 – 1.11 0.043 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 1.11 0.953 – 1.29 0.181 175 1748 all phecode
783 Fever of unknown origin Symptoms 0.981 0.949 – 1.01 0.272 3911 39105 all phecode
785 Abdominal pain Symptoms 1.01 1 – 1.02 0.0231 40080 301686 all phecode
788 Syncope and collapse Symptoms 1.03 1 – 1.05 0.0197 9069 90813 all phecode
789 Nausea and vomiting Symptoms 1.04 1.02 – 1.06 3.75e-05 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 0.99 0.833 – 1.18 0.908 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 1.04 0.827 – 1.3 0.748 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 1 0.979 – 1.03 0.725 6357 63635 all phecode
791 Gangrene Symptoms 0.899 0.821 – 0.985 0.0218 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1.18 0.969 – 1.44 0.1 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1 0.839 – 1.19 0.992 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.08 0.989 – 1.18 0.0884 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.02 0.842 – 1.24 0.838 120 1198 all phecode
797 Shock Symptoms 0.899 0.758 – 1.07 0.22 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 0.905 0.731 – 1.12 0.364 102 1020 all phecode
798 Malaise and fatigue Symptoms 1.01 0.977 – 1.05 0.491 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 0.978 0.897 – 1.07 0.605 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 1.02 0.992 – 1.04 0.179 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.993 0.946 – 1.04 0.777 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.889 0.755 – 1.05 0.159 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.03 0.99 – 1.08 0.13 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 0.959 0.89 – 1.03 0.267 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.04 0.996 – 1.09 0.0736 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.06 1.01 – 1.11 0.0151 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.995 0.921 – 1.08 0.901 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 1.02 0.998 – 1.04 0.0767 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.02 0.971 – 1.07 0.419 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.03 0.996 – 1.06 0.0856 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.04 0.986 – 1.1 0.149 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.979 0.944 – 1.02 0.256 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.05 0.991 – 1.11 0.103 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 1.07 0.993 – 1.15 0.0751 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.06 1 – 1.12 0.0478 1300 12998 all phecode
817 Concussion Injuries & Poisonings 1.23 1.08 – 1.41 0.00184 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.953 0.869 – 1.04 0.297 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.03 0.99 – 1.07 0.146 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 1.04 0.99 – 1.09 0.116 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 1.02 0.979 – 1.07 0.302 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 1 0.985 – 1.02 0.881 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.05 0.956 – 1.14 0.329 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 0.988 0.897 – 1.09 0.802 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.05 1.02 – 1.08 0.000322 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.03 0.878 – 1.22 0.683 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 0.999 0.911 – 1.09 0.979 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.03 0.982 – 1.08 0.224 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.987 0.93 – 1.05 0.669 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.01 0.969 – 1.04 0.782 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.03 0.993 – 1.07 0.109 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1.04 0.803 – 1.34 0.785 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.04 1.01 – 1.08 0.018 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.02 0.895 – 1.15 0.801 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 1.06 0.914 – 1.22 0.457 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.04 1 – 1.08 0.0436 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.11 0.965 – 1.27 0.148 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 0.971 0.751 – 1.26 0.821 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 0.977 0.946 – 1.01 0.165 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.2 0.919 – 1.58 0.178 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.11 0.904 – 1.36 0.319 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.01 0.87 – 1.18 0.856 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 0.934 0.849 – 1.03 0.157 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 0.973 0.85 – 1.11 0.69 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 0.974 0.833 – 1.14 0.74 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.01 0.859 – 1.19 0.906 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.01 0.95 – 1.07 0.831 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.05 1.02 – 1.08 0.00329 4260 42663 all phecode
916 Contusion Injuries & Poisonings 1.04 0.983 – 1.1 0.184 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.963 0.824 – 1.13 0.635 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.3 1.17 – 1.44 6.39e-07 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 1.36 1.19 – 1.54 3.39e-06 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.04 0.993 – 1.09 0.0932 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.888 0.774 – 1.02 0.0912 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.01 0.83 – 1.24 0.886 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.02 0.936 – 1.12 0.627 550 5509 all phecode
947 Urticaria Injuries & Poisonings 1.02 0.921 – 1.14 0.653 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 1.13 1.02 – 1.25 0.0216 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.09 0.985 – 1.2 0.0953 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.96 0.845 – 1.09 0.523 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.947 0.862 – 1.04 0.256 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 0.998 0.758 – 1.32 0.991 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.829 0.648 – 1.06 0.137 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1 0.988 – 1.02 0.629 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.996 0.98 – 1.01 0.654 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.05 0.95 – 1.16 0.346 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.02 0.951 – 1.09 0.577 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.08 0.97 – 1.2 0.164 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.947 – 1.17 0.337 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.03 0.898 – 1.19 0.649 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.996 0.88 – 1.13 0.955 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.03 0.908 – 1.17 0.655 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.986 0.961 – 1.01 0.317 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.07 1 – 1.13 0.0395 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.06 0.967 – 1.17 0.211 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.943 – 1.16 0.396 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.02 0.935 – 1.12 0.621 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1 0.918 – 1.09 0.967 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.02 0.973 – 1.07 0.434 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.933 0.801 – 1.09 0.378 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.03 0.91 – 1.17 0.617 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.02 0.82 – 1.27 0.848 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.25 1.03 – 1.53 0.0267 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.953 0.772 – 1.18 0.654 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.931 0.726 – 1.19 0.574 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.985 0.749 – 1.3 0.915 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.1 0.959 – 1.25 0.177 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.02 0.945 – 1.1 0.59 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.893 0.769 – 1.04 0.134 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.17 0.903 – 1.51 0.238 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.26 1.03 – 1.53 0.0237 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.772 0.627 – 0.95 0.0145 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.972 0.781 – 1.21 0.8 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.02 0.979 – 1.05 0.401 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.01 0.97 – 1.05 0.718 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 1.01 0.97 – 1.05 0.718 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 1.01 0.986 – 1.03 0.475 8412 85066 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.03 0.987 – 1.07 0.182 2590 26097 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.03 0.951 – 1.13 0.425 607 6267 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.01 0.944 – 1.09 0.697 808 8275 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.11 0.851 – 1.46 0.432 53 533 exclusion phecode
010 Tuberculosis Infectious Diseases 1.03 0.871 – 1.21 0.756 160 1591 exclusion phecode
038 Septicemia Infectious Diseases 1 0.969 – 1.04 0.936 3950 40058 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.02 0.952 – 1.1 0.517 803 8157 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.02 0.926 – 1.12 0.709 473 4756 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.01 0.989 – 1.03 0.406 11405 115675 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.03 0.99 – 1.07 0.15 2961 30113 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 0.988 0.937 – 1.04 0.646 1554 15843 exclusion phecode
041.4 E. coli Infectious Diseases 1.01 0.973 – 1.06 0.517 2597 26247 exclusion phecode
053 Herpes zoster Infectious Diseases 0.951 0.856 – 1.06 0.354 391 3973 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.963 0.776 – 1.2 0.735 94 917 exclusion phecode
054 Herpes simplex Infectious Diseases 1.05 0.91 – 1.21 0.51 203 2046 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.05 0.962 – 1.14 0.28 564 5729 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 0.901 0.698 – 1.16 0.423 66 665 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 1.21 1.01 – 1.44 0.0386 123 1288 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.06 0.927 – 1.2 0.413 247 2508 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.04 0.913 – 1.18 0.562 253 2668 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.02 0.919 – 1.13 0.733 403 4124 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.13 0.954 – 1.35 0.155 137 1434 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.17 0.965 – 1.41 0.112 109 1140 exclusion phecode
078 Viral warts & HPV Infectious Diseases 1.11 1.04 – 1.18 0.00268 913 9745 exclusion phecode
079 Viral infection Infectious Diseases 1.01 0.966 – 1.05 0.796 2656 26812 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.927 0.712 – 1.21 0.571 60 626 exclusion phecode
080 Postoperative infection Infectious Diseases 1 0.972 – 1.04 0.828 4234 43158 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.02 0.979 – 1.07 0.32 2353 23841 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.07 0.843 – 1.36 0.58 68 686 exclusion phecode
1000 Burns Injuries & Poisonings 0.978 0.896 – 1.07 0.612 563 5594 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 1.03 0.968 – 1.09 0.366 1144 11630 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1 0.975 – 1.03 0.825 5237 52687 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.03 0.912 – 1.16 0.632 292 2882 exclusion phecode
1005 Other symptoms Injuries & Poisonings 1.03 0.976 – 1.09 0.269 1375 13869 exclusion phecode
1006 Crushing injury Injuries & Poisonings 0.975 0.857 – 1.11 0.705 245 2476 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 1.04 0.916 – 1.19 0.524 249 2478 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.05 0.986 – 1.13 0.125 964 9771 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 1.03 1 – 1.05 0.0334 8207 82098 exclusion phecode
1010 Other tests Injuries & Poisonings 1.02 0.992 – 1.05 0.163 5692 57250 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.01 0.992 – 1.04 0.207 8702 87961 exclusion phecode
1012 Late effect Injuries & Poisonings 1.05 0.868 – 1.28 0.597 102 1014 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 0.995 0.883 – 1.12 0.937 305 3051 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.987 0.768 – 1.27 0.918 64 632 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 1.02 0.991 – 1.06 0.157 4026 40821 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.01 0.995 – 1.03 0.15 14883 153567 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.883 0.777 – 1 0.0569 264 2722 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.88 0.774 – 1 0.0518 258 2667 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.04 0.82 – 1.32 0.737 67 725 exclusion phecode
110.12 Althete's foot Infectious Diseases 0.793 0.662 – 0.951 0.0121 134 1370 exclusion phecode
112 Candidiasis Infectious Diseases 1.04 0.998 – 1.09 0.0634 2020 20395 exclusion phecode
117 Mycoses Infectious Diseases 0.92 0.808 – 1.05 0.208 261 2624 exclusion phecode
117.4 Aspergillosis Infectious Diseases 0.896 0.758 – 1.06 0.2 161 1591 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.934 0.738 – 1.18 0.57 80 764 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 0.846 0.645 – 1.11 0.228 62 668 exclusion phecode
134 Helminthiases Infectious Diseases 1.2 1 – 1.43 0.0475 123 1225 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.16 0.963 – 1.41 0.115 103 1028 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.919 0.79 – 1.07 0.274 193 1974 exclusion phecode
145 Cancer of mouth Neoplasms 1.05 0.966 – 1.14 0.248 583 6143 exclusion phecode
145.2 Cancer of tongue Neoplasms 0.908 0.804 – 1.03 0.119 294 2982 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 1.2 0.972 – 1.48 0.0898 96 1009 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.03 0.787 – 1.36 0.813 52 510 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.04 0.957 – 1.13 0.356 593 6064 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.03 0.902 – 1.18 0.646 238 2405 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.06 0.932 – 1.2 0.394 252 2503 exclusion phecode
150 Cancer of esophagus Neoplasms 0.964 0.893 – 1.04 0.349 727 7280 exclusion phecode
151 Cancer of stomach Neoplasms 0.977 0.894 – 1.07 0.598 545 5416 exclusion phecode
153 Colorectal cancer Neoplasms 0.997 0.966 – 1.03 0.865 4289 43805 exclusion phecode
153.2 Colon cancer Neoplasms 1 0.963 – 1.04 0.951 2922 29675 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.996 0.951 – 1.04 0.86 2018 20705 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.936 0.841 – 1.04 0.226 382 3822 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.992 0.839 – 1.17 0.921 149 1509 exclusion phecode
157 Pancreatic cancer Neoplasms 0.975 0.897 – 1.06 0.548 633 6289 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.992 0.929 – 1.06 0.815 999 10182 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.987 0.959 – 1.02 0.371 5198 53215 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.01 0.864 – 1.17 0.927 181 1819 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.865 0.743 – 1.01 0.0611 194 1950 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.03 0.885 – 1.2 0.7 185 1841 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 1.32 1.02 – 1.71 0.0354 58 573 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.06 1.02 – 1.1 0.00365 2668 26957 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.05 1.01 – 1.1 0.0187 2121 21338 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 1.04 0.936 – 1.15 0.475 385 4177 exclusion phecode
170.1 Bone cancer Neoplasms 1.15 0.959 – 1.38 0.132 118 1245 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1.01 0.895 – 1.14 0.887 292 3183 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.18 0.994 – 1.39 0.0583 137 1818 exclusion phecode
174 Breast cancer Neoplasms 1.02 1 – 1.04 0.0319 12111 122349 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1.02 1 – 1.04 0.0278 11917 120336 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.02 1 – 1.04 0.024 11228 113531 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.894 0.733 – 1.09 0.271 111 1111 exclusion phecode
175 Acquired absence of breast Neoplasms 1.03 0.986 – 1.07 0.19 2282 23220 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 0.987 0.943 – 1.03 0.563 2119 21229 exclusion phecode
180.1 Cervical cancer Neoplasms 1.01 0.89 – 1.14 0.903 268 2640 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.984 0.939 – 1.03 0.495 2025 20287 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.988 0.931 – 1.05 0.678 1226 12355 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.05 0.994 – 1.11 0.0808 1303 13299 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.09 1.02 – 1.17 0.00973 926 9332 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.09 1.02 – 1.17 0.00943 899 9058 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.96 0.848 – 1.09 0.522 279 2963 exclusion phecode
185 Cancer of prostate Neoplasms 0.987 0.96 – 1.02 0.375 5586 55793 exclusion phecode
187 Cancer of other male genital organs Neoplasms 1 0.908 – 1.11 0.946 425 4350 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.09 0.842 – 1.42 0.502 60 675 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 1.02 0.903 – 1.15 0.75 277 2799 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.01 0.829 – 1.23 0.909 107 1048 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1 0.968 – 1.04 0.945 3923 39646 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.995 0.932 – 1.06 0.887 1016 10245 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.992 0.928 – 1.06 0.82 983 9870 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.1 0.835 – 1.45 0.496 58 622 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.01 0.968 – 1.06 0.628 2284 22927 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.993 0.948 – 1.04 0.783 2032 20386 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.15 0.964 – 1.38 0.118 129 1369 exclusion phecode
190 Cancer of eye Neoplasms 1.27 1.08 – 1.49 0.00459 147 1679 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.04 0.959 – 1.13 0.344 661 6593 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 1.03 0.94 – 1.12 0.563 543 5411 exclusion phecode
191.11 Cancer of brain Neoplasms 1.02 0.934 – 1.12 0.619 503 5023 exclusion phecode
193 Thyroid cancer Neoplasms 1.08 0.966 – 1.21 0.173 327 3350 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 0.997 0.802 – 1.24 0.976 91 909 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.03 1.01 – 1.05 0.00208 13554 160056 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.03 1.01 – 1.05 0.00179 12892 154276 exclusion phecode
197 Chemotherapy Neoplasms 1.02 1.01 – 1.04 0.0011 20337 206935 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.02 0.998 – 1.04 0.0726 8817 92416 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.03 1 – 1.06 0.0527 4917 52033 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.01 0.963 – 1.06 0.735 2068 21940 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.02 0.968 – 1.08 0.426 1435 15001 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.02 0.974 – 1.06 0.467 2495 25756 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.02 0.947 – 1.1 0.582 755 8236 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.02 0.975 – 1.07 0.376 2029 20888 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.09 0.905 – 1.3 0.376 114 1836 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.03 0.97 – 1.09 0.358 1346 13849 exclusion phecode
199.4 Neurofibromatosis Neoplasms 0.918 0.738 – 1.14 0.442 92 929 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.01 0.94 – 1.08 0.842 920 9480 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.02 0.914 – 1.14 0.725 365 3692 exclusion phecode
201 Hodgkin's disease Neoplasms 1.09 0.96 – 1.24 0.181 250 2507 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.04 0.991 – 1.09 0.114 2068 21780 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.05 0.998 – 1.1 0.0595 1664 17309 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.01 0.9 – 1.13 0.862 338 3500 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.09 1 – 1.19 0.0505 540 5562 exclusion phecode
204 Leukemia Neoplasms 1.02 0.967 – 1.08 0.462 1518 15908 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1.08 0.981 – 1.18 0.12 514 5524 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.885 0.655 – 1.2 0.427 53 545 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.09 0.988 – 1.2 0.0869 449 4844 exclusion phecode
204.2 Myeloid leukemia Neoplasms 0.953 0.861 – 1.05 0.352 435 4437 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.985 0.873 – 1.11 0.803 312 3151 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.905 0.753 – 1.09 0.288 131 1392 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.07 0.98 – 1.17 0.13 515 5338 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1.03 1.01 – 1.04 0.0011 18851 184234 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.04 0.974 – 1.12 0.229 949 9456 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.02 0.986 – 1.05 0.302 5005 50355 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.948 0.847 – 1.06 0.358 335 3331 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.13 1 – 1.27 0.0417 307 3109 exclusion phecode
214 Lipoma Neoplasms 0.993 0.967 – 1.02 0.614 5928 60147 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.996 0.966 – 1.03 0.823 4355 44315 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.995 0.933 – 1.06 0.868 1048 10681 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.915 0.891 – 0.939 2.05e-11 6446 74370 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.02 0.939 – 1.12 0.603 565 6102 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 1.04 0.955 – 1.14 0.341 531 5747 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.993 0.972 – 1.01 0.506 9703 97465 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 1 0.981 – 1.02 0.857 9913 99546 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.939 0.837 – 1.05 0.288 337 3457 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 1.04 0.982 – 1.1 0.185 1396 14013 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 1 0.868 – 1.16 0.956 206 2124 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.897 0.755 – 1.07 0.217 154 1535 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.06 0.903 – 1.24 0.478 166 1658 exclusion phecode
224 Benign neoplasm of eye Neoplasms 1.22 1.02 – 1.47 0.0321 123 1229 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.42 1.11 – 1.81 0.00539 65 640 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.01 0.934 – 1.09 0.846 777 7865 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.01 0.934 – 1.09 0.824 736 7482 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.05 0.807 – 1.36 0.737 59 561 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.08 0.953 – 1.23 0.224 255 2581 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.04 0.963 – 1.11 0.346 819 8320 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.19 1.01 – 1.39 0.0327 178 1782 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.07 0.954 – 1.19 0.254 350 3573 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.965 0.855 – 1.09 0.561 295 2993 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.03 0.978 – 1.09 0.244 1462 15403 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.846 0.808 – 0.886 1.68e-12 2100 23224 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.972 0.89 – 1.06 0.521 569 5799 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.972 0.911 – 1.04 0.383 1035 10684 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.91 0.825 – 1 0.0598 442 4527 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.04 0.954 – 1.12 0.398 631 6534 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.08 1.03 – 1.14 0.000969 1785 17871 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 1.12 1.02 – 1.23 0.021 436 4416 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.14 0.931 – 1.39 0.207 90 887 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 1.19 1 – 1.41 0.0462 135 1338 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.03 1.02 – 1.05 0.000191 13973 139766 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.05 0.983 – 1.12 0.152 1034 10691 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.13 0.915 – 1.39 0.26 96 965 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.03 1.01 – 1.05 0.000411 13343 133846 exclusion phecode
245 Thyroiditis Endocrine/metabolic 1.03 0.909 – 1.16 0.658 280 2777 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.09 0.943 – 1.25 0.253 212 2102 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.08 0.933 – 1.24 0.309 205 2027 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.05 0.949 – 1.17 0.324 376 3821 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.02 1 – 1.03 0.0251 18796 178526 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.08 1.04 – 1.12 0.000222 2644 26570 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.13 0.984 – 1.29 0.0839 233 2312 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.29 1.01 – 1.63 0.0391 74 743 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.07 0.975 – 1.18 0.149 461 4547 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.15 0.98 – 1.36 0.0864 156 1546 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.01 0.997 – 1.03 0.119 16911 163105 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.19 0.976 – 1.45 0.0863 99 1010 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.01 0.876 – 1.17 0.861 192 1926 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.03 0.965 – 1.11 0.346 934 9450 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.01 0.923 – 1.11 0.774 479 4844 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 0.995 0.916 – 1.08 0.897 647 6550 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.03 0.9 – 1.17 0.698 248 2537 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.99 0.891 – 1.1 0.847 400 4026 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.996 0.829 – 1.2 0.962 130 1269 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.01 0.897 – 1.13 0.915 333 3358 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.02 0.966 – 1.09 0.415 1268 12749 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.1 1.03 – 1.18 0.00652 898 8982 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.995 0.926 – 1.07 0.895 815 8406 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.984 0.912 – 1.06 0.683 729 7509 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.957 0.797 – 1.15 0.642 131 1373 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.03 0.947 – 1.11 0.517 647 6546 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.961 0.82 – 1.13 0.625 176 1799 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.938 0.75 – 1.17 0.577 89 908 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.06 0.929 – 1.21 0.377 245 2530 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.16 0.929 – 1.45 0.189 90 889 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.03 0.87 – 1.21 0.748 151 1502 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.962 0.885 – 1.04 0.356 612 6160 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.07 0.918 – 1.25 0.38 171 1733 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.947 0.773 – 1.16 0.598 99 993 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.25 0.985 – 1.59 0.0659 72 734 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.949 0.85 – 1.06 0.357 343 3498 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.948 0.849 – 1.06 0.345 342 3490 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.966 0.843 – 1.11 0.615 234 2364 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.923 0.799 – 1.07 0.276 204 2062 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1.17 0.983 – 1.39 0.0769 150 1561 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.12 0.938 – 1.33 0.216 143 1483 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.883 0.716 – 1.09 0.243 99 972 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 1.07 0.907 – 1.27 0.415 144 1448 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.03 0.886 – 1.19 0.733 189 1948 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.05 0.975 – 1.13 0.197 785 8013 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.06 0.993 – 1.12 0.0821 1142 11533 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.06 0.986 – 1.15 0.11 724 7251 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.03 0.932 – 1.14 0.555 421 4301 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.954 0.757 – 1.2 0.69 73 739 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.04 0.91 – 1.19 0.545 232 2331 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.1 0.981 – 1.23 0.102 324 3241 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.06 0.939 – 1.2 0.345 276 2888 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.05 0.925 – 1.2 0.425 236 2481 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.03 0.888 – 1.2 0.669 179 1803 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1.02 0.836 – 1.24 0.851 108 1078 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.06 0.814 – 1.39 0.65 57 659 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.932 0.783 – 1.11 0.432 149 1544 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.9 0.744 – 1.09 0.275 129 1341 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1 0.991 – 1.01 0.616 32927 226850 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1 0.991 – 1.01 0.651 32866 226625 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1 0.99 – 1.01 0.751 30544 219659 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.06 0.806 – 1.38 0.693 57 544 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.941 0.798 – 1.11 0.469 159 1578 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.09 0.938 – 1.26 0.268 196 2023 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.997 0.963 – 1.03 0.868 3503 35620 exclusion phecode
274.1 Gout Endocrine/metabolic 0.998 0.961 – 1.04 0.921 2970 30292 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.05 0.861 – 1.28 0.641 107 1079 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.01 0.924 – 1.1 0.855 589 5881 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1 0.913 – 1.1 0.996 537 5354 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.01 0.966 – 1.06 0.601 1979 20209 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.952 0.876 – 1.04 0.251 617 6267 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.03 0.921 – 1.15 0.608 345 3594 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.07 1 – 1.13 0.0386 1132 11535 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.09 0.921 – 1.29 0.316 157 1643 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.02 0.999 – 1.05 0.0578 6899 69742 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.02 0.982 – 1.05 0.372 3866 39125 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.02 0.893 – 1.17 0.75 230 2304 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.05 1 – 1.1 0.0516 1733 17384 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 0.999 0.932 – 1.07 0.985 904 9281 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 0.999 0.943 – 1.06 0.977 1341 13659 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.03 0.965 – 1.09 0.393 1103 11125 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.04 0.973 – 1.11 0.255 1002 10127 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 0.903 0.731 – 1.12 0.346 108 1080 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.02 0.984 – 1.07 0.232 2682 27012 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 0.96 0.867 – 1.06 0.44 413 4323 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 0.962 0.803 – 1.15 0.679 122 1245 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.05 0.974 – 1.12 0.217 860 8589 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1 0.894 – 1.12 0.995 353 3448 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1 0.87 – 1.15 0.98 219 2196 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.01 0.994 – 1.04 0.165 10383 104493 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.01 0.994 – 1.04 0.159 10226 102920 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 0.897 0.713 – 1.13 0.352 80 818 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.03 0.794 – 1.33 0.84 62 632 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.07 0.938 – 1.23 0.299 233 2428 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.1 0.947 – 1.27 0.215 196 2035 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.11 0.929 – 1.32 0.258 130 1341 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.02 0.894 – 1.17 0.766 237 2373 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.03 1 – 1.05 0.0276 7246 73394 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.03 1 – 1.05 0.0337 6958 70465 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.13 1.03 – 1.25 0.013 433 4406 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.12 1.05 – 1.19 0.000411 1068 10696 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.13 1.06 – 1.21 0.000128 1025 10252 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.13 1.05 – 1.22 0.0011 723 7224 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.938 0.798 – 1.1 0.437 167 1711 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 1.21 1.04 – 1.41 0.0135 175 1753 exclusion phecode
281.9 Deficiency anemias Hematopoietic 0.948 0.72 – 1.25 0.703 52 519 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 0.975 0.82 – 1.16 0.779 146 1447 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.13 0.876 – 1.47 0.339 55 543 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.897 0.709 – 1.13 0.365 84 819 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 0.979 0.813 – 1.18 0.824 125 1322 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.885 0.713 – 1.1 0.265 97 1016 exclusion phecode
284 Aplastic anemia Hematopoietic 1.05 0.95 – 1.17 0.318 399 4164 exclusion phecode
285 Other anemias Hematopoietic 1.03 1.01 – 1.05 0.00248 11494 116451 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.941 0.827 – 1.07 0.36 255 2619 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.07 0.983 – 1.15 0.122 639 6711 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.08 0.97 – 1.19 0.167 389 3980 exclusion phecode
286 Coagulation defects Hematopoietic 1.01 0.944 – 1.09 0.719 883 8905 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 1.01 0.914 – 1.11 0.851 442 4441 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.914 0.74 – 1.13 0.405 93 923 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.02 0.899 – 1.15 0.783 283 2850 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.08 0.83 – 1.41 0.562 62 603 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.01 0.805 – 1.26 0.949 81 822 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.07 0.958 – 1.19 0.233 370 3735 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.01 0.96 – 1.07 0.651 1549 15843 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.08 0.903 – 1.3 0.383 121 1241 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1 0.949 – 1.06 0.958 1457 14897 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.01 0.912 – 1.12 0.815 389 4017 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.947 0.746 – 1.2 0.651 73 729 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.02 0.983 – 1.05 0.311 3532 36245 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.01 0.971 – 1.05 0.65 2968 30475 exclusion phecode
288.11 Neutropenia Hematopoietic 1.01 0.973 – 1.05 0.576 2976 30557 exclusion phecode
288.3 Eosinophilia Hematopoietic 1.05 0.815 – 1.35 0.706 68 682 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.06 0.99 – 1.15 0.0925 818 8260 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.1 0.97 – 1.25 0.138 276 2782 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.04 0.998 – 1.08 0.0647 2435 25074 exclusion phecode
289.5 Diseases of spleen Hematopoietic 0.97 0.882 – 1.07 0.533 482 4939 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.02 0.897 – 1.15 0.802 280 2803 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.13 0.906 – 1.41 0.276 85 858 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.09 1.04 – 1.14 0.000513 1822 18297 exclusion phecode
290.1 Dementias Mental Disorders 1.09 1.02 – 1.16 0.0139 940 9496 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 1.03 0.932 – 1.14 0.552 406 4090 exclusion phecode
290.16 Vascular dementia Mental Disorders 1.24 1.07 – 1.43 0.0052 186 1895 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.08 0.994 – 1.17 0.0703 620 6201 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.1 0.862 – 1.41 0.437 68 691 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.11 1.03 – 1.2 0.004 802 8094 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.952 0.79 – 1.15 0.604 130 1284 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.09 0.964 – 1.24 0.167 273 2747 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.17 1.05 – 1.29 0.00271 417 4232 exclusion phecode
292 Neurological disorders Mental Disorders 1.01 0.982 – 1.05 0.408 4420 44272 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.05 0.994 – 1.11 0.0787 1439 14469 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 1.05 0.896 – 1.22 0.57 180 1825 exclusion phecode
292.3 Memory loss Mental Disorders 0.979 0.902 – 1.06 0.613 666 6697 exclusion phecode
292.4 Altered mental status Mental Disorders 0.988 0.943 – 1.03 0.604 2087 20833 exclusion phecode
292.6 Hallucinations Mental Disorders 1.11 0.991 – 1.25 0.0703 291 2961 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.02 0.977 – 1.07 0.334 1996 20116 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.04 0.967 – 1.11 0.305 837 8670 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.01 0.943 – 1.09 0.725 824 8200 exclusion phecode
295.1 Schizophrenia Mental Disorders 0.996 0.914 – 1.09 0.927 564 5612 exclusion phecode
295.2 Paranoid disorders Mental Disorders 0.992 0.847 – 1.16 0.922 177 1721 exclusion phecode
295.3 Psychosis Mental Disorders 1.01 0.862 – 1.19 0.858 164 1655 exclusion phecode
296 Mood disorders Mental Disorders 1.01 0.993 – 1.03 0.202 11929 119969 exclusion phecode
296.1 Bipolar Mental Disorders 1.04 0.973 – 1.11 0.262 1025 10309 exclusion phecode
296.2 Depression Mental Disorders 1.01 0.991 – 1.03 0.272 11309 113778 exclusion phecode
296.22 Major depressive disorder Mental Disorders 0.933 0.833 – 1.05 0.233 346 3487 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.971 0.866 – 1.09 0.611 302 2990 exclusion phecode
300 Anxiety disorders Mental Disorders 1.02 0.993 – 1.04 0.163 6602 66124 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.02 0.989 – 1.04 0.255 6090 61089 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 1.04 0.875 – 1.24 0.632 141 1451 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.02 0.943 – 1.11 0.605 684 6830 exclusion phecode
300.13 Phobia Mental Disorders 0.964 0.877 – 1.06 0.452 485 4835 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.14 0.963 – 1.35 0.128 137 1366 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.17 0.881 – 1.54 0.284 52 514 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.13 0.938 – 1.36 0.196 123 1204 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.961 0.792 – 1.17 0.688 112 1099 exclusion phecode
301 Personality disorders Mental Disorders 1.07 0.951 – 1.2 0.271 328 3256 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.08 0.9 – 1.31 0.397 116 1160 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 0.969 0.852 – 1.1 0.626 272 2718 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.05 0.948 – 1.15 0.374 450 4527 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 1.09 0.973 – 1.21 0.141 339 3400 exclusion phecode
303.4 Somatoform disorder Mental Disorders 1.03 0.859 – 1.24 0.738 118 1193 exclusion phecode
304 Adjustment reaction Mental Disorders 0.992 0.876 – 1.12 0.9 286 2875 exclusion phecode
305.2 Eating disorder Mental Disorders 1.06 0.847 – 1.32 0.627 86 887 exclusion phecode
306 Other mental disorder Mental Disorders 1.02 1 – 1.03 0.0187 26690 221620 exclusion phecode
306.9 Tension headache Mental Disorders 1.01 0.901 – 1.14 0.811 305 3045 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 1.03 0.813 – 1.3 0.813 75 755 exclusion phecode
313.3 Autism Mental Disorders 1.13 0.849 – 1.49 0.409 53 528 exclusion phecode
315 Develomental delays and disorders Mental Disorders 0.977 0.874 – 1.09 0.689 333 3381 exclusion phecode
315.1 Learning disorder Mental Disorders 1.28 1.08 – 1.5 0.00335 153 1568 exclusion phecode
315.2 Speech and language disorder Mental Disorders 1.13 0.917 – 1.4 0.248 86 840 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.05 1.02 – 1.08 0.00133 5140 51323 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.917 0.694 – 1.21 0.538 56 575 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.04 1.02 – 1.06 6.09e-06 12190 122357 exclusion phecode
317.1 Alcoholism Mental Disorders 1.04 1.02 – 1.07 0.000135 8512 85617 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.08 1.01 – 1.16 0.0325 813 8095 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.01 0.995 – 1.03 0.207 18606 179029 exclusion phecode
320 Meningitis Neurological 0.925 0.836 – 1.02 0.13 428 4296 exclusion phecode
323 Encephalitis Neurological 0.991 0.883 – 1.11 0.878 331 3293 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 0.917 0.709 – 1.18 0.507 73 718 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 0.97 0.856 – 1.1 0.627 279 2787 exclusion phecode
327 Sleep disorders Neurological 1.03 0.971 – 1.1 0.31 1115 11220 exclusion phecode
327.3 Sleep apnea Neurological 1.02 0.985 – 1.05 0.316 4252 42671 exclusion phecode
327.4 Insomnia Neurological 1.06 0.895 – 1.26 0.501 147 1594 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.04 0.859 – 1.25 0.715 122 1333 exclusion phecode
331 Other cerebral degenerations Neurological 0.995 0.934 – 1.06 0.873 1089 10943 exclusion phecode
331.1 Hydrocephalus Neurological 0.968 0.878 – 1.07 0.512 481 4830 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.04 0.935 – 1.15 0.499 408 4112 exclusion phecode
332 Parkinson's disease Neurological 1.01 0.944 – 1.07 0.827 1033 10688 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.06 0.989 – 1.14 0.0951 843 8622 exclusion phecode
333.1 Essential tremor Neurological 1.03 0.885 – 1.19 0.733 197 2057 exclusion phecode
333.2 Myoclonus Neurological 0.992 0.801 – 1.23 0.941 93 922 exclusion phecode
333.4 Torsion dystonia Neurological 1.05 0.918 – 1.2 0.481 239 2420 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.01 0.961 – 1.06 0.681 1732 17414 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.06 0.879 – 1.28 0.535 111 1128 exclusion phecode
334.2 Anterior horn cell disease Neurological 1.07 0.936 – 1.22 0.327 234 2343 exclusion phecode
335 Multiple sclerosis Neurological 0.974 0.919 – 1.03 0.373 1294 12970 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 0.961 0.843 – 1.1 0.55 252 2548 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 0.999 0.777 – 1.28 0.993 69 681 exclusion phecode
338 Pain Neurological 0.984 0.911 – 1.06 0.671 730 7413 exclusion phecode
338.1 Acute pain Neurological 0.937 0.842 – 1.04 0.232 371 3788 exclusion phecode
338.2 Chronic pain Neurological 0.998 0.897 – 1.11 0.967 365 3691 exclusion phecode
339 Other headache syndromes Neurological 1.01 0.985 – 1.03 0.461 7554 75796 exclusion phecode
340 Migraine Neurological 0.994 0.955 – 1.03 0.762 2766 27738 exclusion phecode
340.1 Migrain with aura Neurological 0.963 0.831 – 1.12 0.611 209 2057 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.01 0.89 – 1.15 0.873 249 2465 exclusion phecode
342 Hemiplegia Neurological 0.995 0.942 – 1.05 0.867 1429 14345 exclusion phecode
343 Infantile cerebral palsy Neurological 1.09 0.918 – 1.29 0.328 141 1414 exclusion phecode
344 Other paralytic syndromes Neurological 1.03 0.951 – 1.12 0.441 635 6332 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.02 0.992 – 1.05 0.158 4797 48477 exclusion phecode
345.1 Epilepsy Neurological 1.01 0.94 – 1.08 0.79 823 8352 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.06 0.964 – 1.17 0.22 422 4237 exclusion phecode
345.12 Partial epilepsy Neurological 1.05 0.929 – 1.18 0.44 270 2678 exclusion phecode
345.3 Convulsions Neurological 1.06 1.01 – 1.1 0.0177 2142 21515 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.918 0.767 – 1.1 0.35 136 1372 exclusion phecode
348 Other conditions of brain Neurological 1.06 0.98 – 1.14 0.151 752 7537 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.02 0.895 – 1.15 0.797 260 2584 exclusion phecode
348.4 Cerebral cysts Neurological 0.956 0.799 – 1.14 0.619 130 1309 exclusion phecode
348.7 Coma Neurological 1.1 0.985 – 1.23 0.09 346 3458 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.12 0.984 – 1.28 0.0839 239 2417 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.07 0.962 – 1.19 0.212 363 3750 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.97 0.864 – 1.09 0.609 326 3297 exclusion phecode
350 Abnormal movement Neurological 1.05 1 – 1.09 0.0342 2550 25562 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.04 0.968 – 1.12 0.29 839 8471 exclusion phecode
350.2 Abnormality of gait Neurological 1.05 0.997 – 1.11 0.0661 1534 15228 exclusion phecode
350.3 Lack of coordination Neurological 1.13 1.01 – 1.26 0.0325 344 3487 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.957 0.716 – 1.28 0.765 52 516 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.02 0.998 – 1.04 0.0797 11955 119916 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.03 0.971 – 1.09 0.339 1302 13208 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1 0.909 – 1.11 0.956 444 4476 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.06 0.99 – 1.14 0.0907 834 8485 exclusion phecode
353 Nerve root and plexus disorders Neurological 1.01 0.946 – 1.07 0.808 1084 10872 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.882 0.721 – 1.08 0.22 109 1099 exclusion phecode
353.2 Nerve root lesions Neurological 1.01 0.761 – 1.33 0.972 54 548 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.995 0.839 – 1.18 0.954 147 1450 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 0.955 0.902 – 1.01 0.122 1300 13076 exclusion phecode
358 Myoneural disorders Neurological 1.1 0.953 – 1.26 0.199 206 2028 exclusion phecode
358.1 Myasthenia gravis Neurological 1.1 0.946 – 1.27 0.223 187 1837 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 1.1 0.994 – 1.21 0.0653 446 4488 exclusion phecode
359.1 Muscular dystrophies Neurological 1.05 0.866 – 1.26 0.641 118 1190 exclusion phecode
359.2 Myopathy Neurological 1.11 0.995 – 1.24 0.0622 343 3464 exclusion phecode
360 Disorders of the globe Sense Organs 1.07 0.958 – 1.2 0.223 327 3234 exclusion phecode
360.2 Progressive myopia Sense Organs 1.12 0.977 – 1.27 0.105 243 2412 exclusion phecode
361 Retinal detachments and defects Sense Organs 1.01 0.972 – 1.05 0.643 3125 31157 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.04 0.986 – 1.1 0.14 1335 13343 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.782 0.598 – 1.02 0.0728 65 655 exclusion phecode
362 Other retinal disorders Sense Organs 1.01 0.974 – 1.04 0.634 3662 36610 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.01 0.967 – 1.06 0.614 2082 20770 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.01 0.968 – 1.06 0.568 2079 20742 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.958 0.806 – 1.14 0.623 153 1539 exclusion phecode
362.31 Separation of retinal layers Sense Organs 0.969 0.783 – 1.2 0.776 95 943 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.99 0.919 – 1.07 0.795 818 8096 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 1.01 0.856 – 1.18 0.938 170 1750 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1 0.792 – 1.27 0.978 80 782 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.961 0.788 – 1.17 0.69 113 1114 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.13 0.965 – 1.32 0.129 162 1625 exclusion phecode
363.3 Chorioretinal scars Sense Organs 1.08 0.848 – 1.39 0.518 64 662 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.01 0.924 – 1.09 0.904 611 6208 exclusion phecode
364.1 Corneal opacity Sense Organs 1.14 0.913 – 1.42 0.251 85 874 exclusion phecode
364.2 Corneal edema Sense Organs 0.936 0.736 – 1.19 0.587 72 769 exclusion phecode
364.4 Corneal degenerations Sense Organs 1 0.859 – 1.16 0.996 194 1934 exclusion phecode
364.41 Keratoconus Sense Organs 0.955 0.762 – 1.2 0.686 83 837 exclusion phecode
364.5 Corneal dystrophy Sense Organs 1.09 0.94 – 1.26 0.252 195 2029 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 1.25 1.01 – 1.54 0.0376 96 957 exclusion phecode
365 Glaucoma Sense Organs 1.03 0.998 – 1.06 0.0702 4159 42129 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 1.09 1.02 – 1.16 0.0157 967 9860 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 1.09 1.02 – 1.16 0.0118 961 9812 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.999 0.922 – 1.08 0.976 664 6679 exclusion phecode
366 Cataract Sense Organs 1.02 1.01 – 1.04 0.00179 18922 161250 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 1.08 0.847 – 1.38 0.527 68 674 exclusion phecode
366.2 Senile cataract Sense Organs 1.03 1 – 1.05 0.0297 7791 77972 exclusion phecode
366.3 Traumatic cataract Sense Organs 0.972 0.79 – 1.2 0.792 99 982 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.01 0.971 – 1.06 0.523 2294 23098 exclusion phecode
367.1 Myopia Sense Organs 1.02 0.964 – 1.09 0.439 1196 11982 exclusion phecode
367.2 Astigmatism Sense Organs 1.18 1.01 – 1.37 0.0319 178 1823 exclusion phecode
367.8 Hypermetropia Sense Organs 0.992 0.866 – 1.14 0.906 239 2428 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.01 0.929 – 1.09 0.881 687 6916 exclusion phecode
368 Visual disturbances Sense Organs 1.02 0.986 – 1.07 0.219 2828 28519 exclusion phecode
368.1 Amblyopia Sense Organs 1.13 1.03 – 1.23 0.0104 505 5072 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.02 0.939 – 1.1 0.681 693 7043 exclusion phecode
368.3 Anisometropia Sense Organs 1.03 0.863 – 1.22 0.77 145 1471 exclusion phecode
368.4 Visual field defects Sense Organs 1.09 0.972 – 1.22 0.143 310 3204 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.995 0.914 – 1.08 0.917 583 5919 exclusion phecode
369 Infection of the eye Sense Organs 1.06 0.97 – 1.16 0.197 520 5329 exclusion phecode
369.2 Eye infection, viral Sense Organs 1.14 0.936 – 1.38 0.197 120 1212 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 1.16 1.01 – 1.34 0.0341 202 2054 exclusion phecode
370 Keratitis Sense Organs 0.968 0.853 – 1.1 0.617 277 2756 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.987 0.826 – 1.18 0.889 137 1355 exclusion phecode
371 Inflammation of the eye Sense Organs 0.937 0.901 – 0.975 0.0012 2878 29472 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.952 0.864 – 1.05 0.327 455 4667 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.944 0.903 – 0.987 0.0114 2219 22759 exclusion phecode
372 Disorders of conjunctiva Sense Organs 0.948 0.876 – 1.03 0.187 709 7273 exclusion phecode
374 Other disorders of eyelids Sense Organs 1.05 1.02 – 1.08 0.000286 5275 54526 exclusion phecode
374.1 Ectropion or entropion Sense Organs 1.12 1.04 – 1.19 0.00112 969 10113 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 1.07 1.02 – 1.12 0.00997 1735 17480 exclusion phecode
375 Disorders of lacrimal system Sense Organs 1.03 0.983 – 1.08 0.221 2054 21068 exclusion phecode
375.2 Epiphora Sense Organs 1.04 0.968 – 1.12 0.285 830 8580 exclusion phecode
376 Disorders of the orbit Sense Organs 1.06 0.843 – 1.34 0.597 80 827 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.982 0.878 – 1.1 0.751 346 3492 exclusion phecode
377.1 Optic atrophy Sense Organs 0.718 0.535 – 0.963 0.0271 52 552 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.929 0.767 – 1.12 0.447 121 1223 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.06 0.999 – 1.12 0.056 1357 13602 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.05 0.982 – 1.13 0.149 886 8771 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.969 0.836 – 1.12 0.677 199 2049 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.08 0.948 – 1.22 0.254 264 2653 exclusion phecode
379 Other disorders of eye Sense Organs 1.01 0.979 – 1.05 0.432 3540 35372 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 1 0.947 – 1.06 0.893 1320 13065 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.05 0.996 – 1.1 0.0719 1723 17246 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 0.878 0.674 – 1.14 0.333 69 684 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.926 0.83 – 1.03 0.169 377 3854 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.953 0.808 – 1.12 0.568 159 1625 exclusion phecode
380 Disorders of external ear Sense Organs 0.998 0.916 – 1.09 0.972 582 6151 exclusion phecode
380.1 Otitis externa Sense Organs 1.05 0.955 – 1.15 0.33 485 4934 exclusion phecode
380.4 Impacted cerumen Sense Organs 0.973 0.87 – 1.09 0.633 344 3481 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.01 0.966 – 1.06 0.626 2068 20749 exclusion phecode
381.1 Otitis media Sense Organs 1.02 0.966 – 1.07 0.522 1695 17048 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.01 0.941 – 1.09 0.768 820 8228 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.988 0.851 – 1.15 0.877 189 1867 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.971 0.825 – 1.14 0.726 168 1645 exclusion phecode
381.9 Otorrhea Sense Organs 0.984 0.866 – 1.12 0.808 273 2699 exclusion phecode
382 Otalgia Sense Organs 0.92 0.815 – 1.04 0.182 298 2975 exclusion phecode
383 Otosclerosis Sense Organs 1.11 0.986 – 1.25 0.086 298 2987 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.01 0.949 – 1.07 0.841 1260 12571 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.01 0.945 – 1.07 0.827 1008 10083 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.05 0.971 – 1.13 0.233 762 7551 exclusion phecode
385.3 Cholesteatoma Sense Organs 1.08 0.996 – 1.18 0.062 594 5849 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.01 0.886 – 1.15 0.867 233 2316 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.05 1 – 1.11 0.0444 1666 16709 exclusion phecode
386.1 Meniere's disease Sense Organs 1.08 0.992 – 1.18 0.0769 552 5542 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.976 0.873 – 1.09 0.663 360 3616 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.07 0.995 – 1.16 0.0672 734 7384 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.05 1.02 – 1.08 0.00308 4379 44026 exclusion phecode
388 Other disorders of ear Sense Organs 1.06 0.916 – 1.23 0.428 197 1940 exclusion phecode
389 Hearing loss Sense Organs 1.04 1.01 – 1.08 0.0124 3973 40174 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 1.01 0.913 – 1.11 0.868 437 4365 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.16 1.06 – 1.28 0.00229 433 4344 exclusion phecode
389.4 Tinnitus Sense Organs 0.976 0.888 – 1.07 0.606 491 4915 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.01 0.98 – 1.04 0.521 4639 46782 exclusion phecode
394.2 Mitral valve disease Circulatory System 0.993 0.955 – 1.03 0.713 2844 28599 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.06 0.995 – 1.12 0.0726 1193 12237 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.02 0.954 – 1.09 0.572 1003 10088 exclusion phecode
395 Heart valve disorders Circulatory System 0.989 0.957 – 1.02 0.52 3988 40328 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.982 0.944 – 1.02 0.377 2744 27611 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.984 0.869 – 1.11 0.804 263 2619 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.13 0.922 – 1.39 0.236 101 1001 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.864 0.691 – 1.08 0.199 89 932 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.04 0.979 – 1.09 0.221 1383 14271 exclusion phecode
396 Abnormal heart sounds Circulatory System 0.932 0.871 – 0.998 0.0423 997 10073 exclusion phecode
401 Hypertension Circulatory System 1.01 0.998 – 1.02 0.118 69829 259278 exclusion phecode
401.1 Essential hypertension Circulatory System 1.01 0.998 – 1.02 0.129 69621 259061 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.05 0.996 – 1.1 0.0735 1742 18224 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1 0.901 – 1.12 0.953 360 3548 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.06 1 – 1.12 0.0502 1397 14831 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.05 0.87 – 1.26 0.616 123 1384 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1 0.949 – 1.06 0.918 1397 14293 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.01 0.995 – 1.02 0.27 29750 202569 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.03 0.996 – 1.06 0.0916 4873 49085 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.01 0.991 – 1.03 0.279 11419 107742 exclusion phecode
411.3 Angina pectoris Circulatory System 1.02 1.01 – 1.04 0.0112 15093 137453 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.01 0.995 – 1.03 0.173 19239 148218 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.947 0.872 – 1.03 0.192 668 6672 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.01 0.993 – 1.03 0.242 14389 125969 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.03 0.971 – 1.1 0.308 1162 11645 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 0.958 0.911 – 1.01 0.0924 1727 17405 exclusion phecode
414.2 ASCVD Circulatory System 0.835 0.639 – 1.09 0.188 69 687 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.02 0.99 – 1.05 0.186 4250 42895 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.929 0.729 – 1.18 0.554 68 718 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.02 0.936 – 1.11 0.635 573 5727 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.02 0.927 – 1.13 0.639 425 4267 exclusion phecode
416 Cardiomegaly Circulatory System 1.04 0.994 – 1.08 0.0953 2552 25564 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.01 0.999 – 1.02 0.0663 27395 260560 exclusion phecode
418.1 Precordial pain Circulatory System 1.05 1.01 – 1.08 0.0116 3429 34246 exclusion phecode
420 Carditis Circulatory System 1.04 0.99 – 1.09 0.125 2018 20168 exclusion phecode
420.1 Myocarditis Circulatory System 0.879 0.726 – 1.07 0.19 117 1202 exclusion phecode
420.2 Pericarditis Circulatory System 1.04 0.979 – 1.1 0.212 1282 12846 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.16 1.01 – 1.33 0.0424 216 2137 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.1 0.912 – 1.33 0.315 108 1079 exclusion phecode
420.3 Endocarditis Circulatory System 1.04 0.964 – 1.13 0.291 689 6872 exclusion phecode
425 Cardiomyopathy Circulatory System 0.989 0.931 – 1.05 0.727 1219 12164 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.988 0.929 – 1.05 0.689 1185 11824 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.969 0.809 – 1.16 0.735 131 1276 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.891 0.755 – 1.05 0.17 159 1562 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.03 0.79 – 1.34 0.828 59 583 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.03 1 – 1.05 0.0512 6543 65983 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.04 0.989 – 1.09 0.136 1994 20151 exclusion phecode
426.21 First degree AV block Circulatory System 1.05 0.981 – 1.12 0.163 932 9399 exclusion phecode
426.23 Second degree AV block Circulatory System 1.04 0.944 – 1.16 0.395 425 4323 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1.01 0.922 – 1.1 0.889 558 5599 exclusion phecode
426.25 Other heart block Circulatory System 0.974 0.811 – 1.17 0.774 126 1263 exclusion phecode
426.3 Bundle branch block Circulatory System 1.02 0.982 – 1.06 0.324 3171 31812 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.03 0.975 – 1.09 0.29 1413 14293 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.01 0.962 – 1.06 0.652 1671 16671 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.985 0.856 – 1.13 0.83 227 2250 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.06 0.806 – 1.39 0.685 54 568 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.03 0.986 – 1.08 0.187 2308 23571 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.02 0.978 – 1.07 0.311 2123 21653 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.01 0.993 – 1.02 0.35 22905 198010 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 0.983 0.947 – 1.02 0.38 3035 30731 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.977 0.934 – 1.02 0.293 2220 22570 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.02 0.953 – 1.09 0.562 890 8918 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.01 0.992 – 1.03 0.271 13783 127510 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.994 0.957 – 1.03 0.752 3047 30885 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.05 0.99 – 1.12 0.0995 1146 11374 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.988 0.882 – 1.11 0.828 328 3276 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.05 0.978 – 1.12 0.194 955 9443 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.987 0.92 – 1.06 0.705 887 9131 exclusion phecode
427.6 Premature beats Circulatory System 1.03 0.938 – 1.13 0.551 509 5157 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1 0.816 – 1.23 0.991 112 1125 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.02 0.972 – 1.06 0.461 2082 21031 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.02 0.916 – 1.13 0.748 379 3828 exclusion phecode
427.9 Palpitations Circulatory System 1.04 1.01 – 1.08 0.0221 3652 36763 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.01 0.982 – 1.04 0.472 5312 53328 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.01 0.964 – 1.06 0.674 2009 20064 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.01 0.976 – 1.04 0.624 4217 42379 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1 0.928 – 1.08 0.958 693 6903 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.12 0.855 – 1.46 0.413 53 607 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1 0.914 – 1.09 0.997 508 5010 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1 0.867 – 1.16 0.96 187 1905 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1 0.951 – 1.05 0.991 1793 18093 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.999 0.929 – 1.07 0.983 807 8088 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.02 0.943 – 1.1 0.614 717 7317 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 0.849 0.743 – 0.97 0.0159 256 2543 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.02 0.996 – 1.04 0.106 8321 83473 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.06 1 – 1.13 0.0473 1132 11251 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.08 0.936 – 1.24 0.301 213 2158 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.05 1.01 – 1.08 0.00523 4026 40341 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.06 1 – 1.11 0.0342 1592 16031 exclusion phecode
433.3 Cerebral ischemia Circulatory System 0.992 0.953 – 1.03 0.678 2739 27601 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.01 0.966 – 1.06 0.615 2024 20377 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1 0.901 – 1.11 0.982 382 3800 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.02 0.964 – 1.09 0.443 1215 12206 exclusion phecode
440 Atherosclerosis Circulatory System 1.01 0.95 – 1.07 0.836 1296 13097 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.04 0.842 – 1.28 0.733 99 1066 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.984 0.912 – 1.06 0.668 760 7662 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 0.955 0.841 – 1.08 0.472 268 2724 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.11 1.02 – 1.2 0.0184 578 5891 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.04 0.921 – 1.18 0.519 266 2701 exclusion phecode
442 Other aneurysm Circulatory System 1.02 0.97 – 1.07 0.468 1784 18045 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.04 0.98 – 1.1 0.207 1369 13859 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.03 0.957 – 1.1 0.465 874 8792 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 0.973 0.789 – 1.2 0.798 93 968 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.05 0.897 – 1.24 0.517 162 1620 exclusion phecode
442.4 Arterial dissection Circulatory System 1.08 0.815 – 1.44 0.587 52 536 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 0.893 0.769 – 1.04 0.142 193 1953 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.04 1 – 1.07 0.0401 3734 37547 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.06 0.995 – 1.13 0.0709 1083 11045 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.943 0.847 – 1.05 0.284 366 3712 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.04 1.01 – 1.08 0.0129 3510 35273 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.04 0.998 – 1.08 0.0603 2464 24573 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.07 0.998 – 1.15 0.0577 876 8807 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.05 0.962 – 1.15 0.271 525 5285 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.952 0.882 – 1.03 0.198 771 7877 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.861 0.731 – 1.01 0.0705 168 1817 exclusion phecode
446.5 Giant cell arteritis Circulatory System 0.967 0.867 – 1.08 0.544 367 3700 exclusion phecode
446.9 Arteritis NOS Circulatory System 0.975 0.85 – 1.12 0.717 227 2299 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.03 0.974 – 1.09 0.281 1272 12704 exclusion phecode
447.1 Stricture of artery Circulatory System 1.06 0.988 – 1.14 0.103 826 8302 exclusion phecode
448 Disease of capillaries Circulatory System 1.15 0.967 – 1.37 0.113 132 1366 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.01 0.933 – 1.1 0.751 649 6770 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.03 0.993 – 1.06 0.114 3748 38112 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.02 0.989 – 1.06 0.171 3487 35516 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 0.963 0.879 – 1.06 0.422 532 5415 exclusion phecode
454 Varicose veins Circulatory System 0.982 0.963 – 1 0.0834 10719 108234 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 0.982 0.963 – 1 0.0688 11037 111288 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.945 0.865 – 1.03 0.203 569 6060 exclusion phecode
455 Hemorrhoids Circulatory System 1.01 0.998 – 1.03 0.085 22449 226271 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.899 0.767 – 1.05 0.189 169 1785 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.98 0.799 – 1.2 0.85 95 920 exclusion phecode
458 Hypotension Circulatory System 1 0.974 – 1.03 0.914 5482 55318 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.03 0.97 – 1.09 0.356 1276 12738 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.13 0.982 – 1.29 0.0887 220 2218 exclusion phecode
458.9 Hypotension NOS Circulatory System 1 0.964 – 1.04 0.999 3319 33577 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.02 1.01 – 1.04 0.00968 15353 154149 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.08 0.898 – 1.29 0.427 132 1358 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.02 1.01 – 1.04 0.0107 15202 152830 exclusion phecode
464 Acute sinusitis Respiratory 0.954 0.823 – 1.11 0.534 189 1890 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1 0.96 – 1.05 0.857 2176 22053 exclusion phecode
465.2 Acute pharyngitis Respiratory 0.951 0.883 – 1.02 0.178 795 8069 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.96 0.813 – 1.13 0.628 158 1584 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.01 0.976 – 1.04 0.658 4504 45103 exclusion phecode
471 Nasal polyps Respiratory 1.04 1 – 1.08 0.0271 3159 31723 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.1 1.03 – 1.18 0.00496 923 9268 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.02 0.978 – 1.06 0.352 2434 24519 exclusion phecode
473.1 Chronic laryngitis Respiratory 0.961 0.781 – 1.18 0.707 99 993 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.05 0.927 – 1.19 0.43 253 2525 exclusion phecode
473.4 Voice disturbance Respiratory 1.06 0.997 – 1.13 0.0609 1034 10320 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 0.974 0.927 – 1.02 0.309 1716 17308 exclusion phecode
474.1 Acute tonsillitis Respiratory 0.983 0.899 – 1.08 0.712 532 5373 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.962 0.903 – 1.02 0.221 1090 10935 exclusion phecode
475 Chronic sinusitis Respiratory 1.02 0.98 – 1.07 0.305 2493 25021 exclusion phecode
476 Allergic rhinitis Respiratory 0.98 0.918 – 1.05 0.551 1003 10254 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 0.952 0.912 – 0.995 0.0276 2334 23396 exclusion phecode
478 Throat pain Respiratory 1.03 0.926 – 1.15 0.555 362 3663 exclusion phecode
479 Other upper respiratory disease Respiratory 1.01 0.98 – 1.05 0.452 3900 39330 exclusion phecode
480 Pneumonia Respiratory 1.01 0.99 – 1.03 0.288 9834 98981 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.01 0.989 – 1.04 0.265 6307 63592 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.02 0.99 – 1.05 0.223 5597 56341 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.03 0.827 – 1.28 0.793 88 893 exclusion phecode
480.2 Viral pneumonia Respiratory 1.14 0.885 – 1.46 0.317 66 701 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.06 0.856 – 1.31 0.606 92 947 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.945 0.876 – 1.02 0.141 750 7582 exclusion phecode
481 Influenza Respiratory 1.01 0.896 – 1.13 0.914 310 3173 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.07 0.919 – 1.25 0.383 186 1857 exclusion phecode
495 Asthma Respiratory 1.01 0.998 – 1.02 0.0999 24617 241883 exclusion phecode
495.2 Asthma with exacerbation Respiratory 0.928 0.809 – 1.06 0.288 236 2431 exclusion phecode
496 Chronic airway obstruction Respiratory 1.02 1 – 1.05 0.0205 9919 97070 exclusion phecode
496.1 Emphysema Respiratory 1.02 0.966 – 1.07 0.524 1662 16623 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.02 0.981 – 1.06 0.324 2832 28138 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.02 0.977 – 1.06 0.404 2600 25831 exclusion phecode
496.3 Bronchiectasis Respiratory 1.02 0.975 – 1.08 0.337 1763 18002 exclusion phecode
497 Bronchitis Respiratory 0.945 0.867 – 1.03 0.203 596 6022 exclusion phecode
500 Lung disease due to external agents Respiratory 1.06 0.952 – 1.17 0.301 386 3860 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.24 0.985 – 1.57 0.0675 74 749 exclusion phecode
500.2 Pneumoconiosis Respiratory 1.04 0.904 – 1.19 0.604 223 2259 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.11 1.02 – 1.2 0.0134 625 6236 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1 0.936 – 1.08 0.907 868 8742 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.03 0.936 – 1.13 0.576 484 4867 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.07 0.955 – 1.2 0.236 313 3131 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 0.951 0.714 – 1.27 0.729 58 581 exclusion phecode
506 Empyema and pneumothorax Respiratory 0.99 0.93 – 1.05 0.761 1085 10893 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.01 0.988 – 1.04 0.281 6085 61409 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.01 0.965 – 1.06 0.623 1904 19117 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.04 0.995 – 1.08 0.0816 2486 24802 exclusion phecode
509.1 Respiratory failure Respiratory 1.04 0.995 – 1.09 0.0789 1976 19714 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.03 0.983 – 1.09 0.201 1732 17239 exclusion phecode
509.5 Respiratory arrest Respiratory 0.965 0.812 – 1.15 0.683 138 1376 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.09 0.981 – 1.22 0.109 370 3672 exclusion phecode
510 Other diseases of lung Respiratory 1.06 0.979 – 1.14 0.159 718 7230 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.03 1.01 – 1.06 0.00497 8621 86785 exclusion phecode
512.1 Wheezing Respiratory 1.1 0.955 – 1.26 0.193 208 2100 exclusion phecode
512.2 Painful respiration Respiratory 0.934 0.809 – 1.08 0.352 200 1995 exclusion phecode
512.7 Shortness of breath Respiratory 1.04 1.01 – 1.07 0.0036 5593 56163 exclusion phecode
512.8 Cough Respiratory 1.04 0.996 – 1.08 0.0803 2716 27537 exclusion phecode
512.9 Other dyspnea Respiratory 1.05 0.984 – 1.13 0.134 874 8767 exclusion phecode
513 Respiratory abnormalities Respiratory 1.07 0.985 – 1.17 0.107 586 5833 exclusion phecode
513.3 Hypoventilation Respiratory 1.02 0.812 – 1.28 0.87 78 793 exclusion phecode
513.4 Hyperventilation Respiratory 0.998 0.879 – 1.13 0.972 269 2673 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.03 0.868 – 1.23 0.709 146 1458 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.03 0.989 – 1.08 0.149 2338 23613 exclusion phecode
516 Abnormal sputum Respiratory 0.983 0.939 – 1.03 0.454 2018 20452 exclusion phecode
516.1 Hemoptysis Respiratory 1 0.955 – 1.05 1 1963 19889 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.03 1.01 – 1.05 0.0133 8889 89900 exclusion phecode
519.2 Respiratory complications Respiratory 1.08 0.964 – 1.21 0.185 310 3127 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.03 1.01 – 1.05 0.00845 8410 84975 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.974 0.862 – 1.1 0.673 284 2921 exclusion phecode
520 Disorders of tooth development Digestive 1.01 0.963 – 1.06 0.703 1983 19810 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.02 0.756 – 1.39 0.88 51 519 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 1.04 0.992 – 1.08 0.108 2298 22943 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.01 0.968 – 1.05 0.763 2905 29257 exclusion phecode
521.1 Dental caries Digestive 1.01 0.97 – 1.05 0.675 2915 29384 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 0.946 0.899 – 0.996 0.0334 1722 17180 exclusion phecode
522.5 Periapical abscess Digestive 0.94 0.883 – 1 0.0513 1136 11343 exclusion phecode
523 Gingival and periodontal diseases Digestive 0.993 0.944 – 1.05 0.796 1634 16280 exclusion phecode
523.1 Gingivitis Digestive 0.987 0.806 – 1.21 0.902 107 1085 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.01 0.95 – 1.07 0.756 1138 11326 exclusion phecode
523.31 Acute periodontitis Digestive 1.05 0.968 – 1.14 0.244 655 6485 exclusion phecode
523.32 Chronic periodontitis Digestive 0.966 0.885 – 1.05 0.433 543 5416 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.04 0.926 – 1.17 0.499 318 3226 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.03 0.914 – 1.17 0.592 295 2975 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.992 0.952 – 1.03 0.714 2586 25791 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.902 0.7 – 1.16 0.427 72 687 exclusion phecode
526 Diseases of the jaws Digestive 0.971 0.905 – 1.04 0.406 891 8998 exclusion phecode
526.1 Cysts of the jaws Digestive 0.996 0.887 – 1.12 0.949 319 3180 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.878 0.676 – 1.14 0.329 61 601 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.03 0.9 – 1.17 0.688 229 2342 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.02 0.889 – 1.16 0.804 222 2275 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.937 0.762 – 1.15 0.535 107 1057 exclusion phecode
526.9 Jaw disease NOS Digestive 0.931 0.809 – 1.07 0.321 219 2248 exclusion phecode
527 Diseases of the salivary glands Digestive 0.972 0.897 – 1.05 0.497 665 6684 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 0.873 0.691 – 1.1 0.252 81 804 exclusion phecode
527.2 Sialoadenitis Digestive 0.968 0.865 – 1.08 0.571 351 3517 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.14 0.884 – 1.48 0.308 58 596 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.04 0.862 – 1.26 0.673 115 1159 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.02 0.989 – 1.06 0.178 3656 37365 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.18 1.07 – 1.3 0.000877 440 4508 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.2 1.08 – 1.33 0.000812 367 3756 exclusion phecode
528.12 Oral aphthae Digestive 1.03 0.818 – 1.3 0.784 78 800 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.956 0.816 – 1.12 0.574 176 1722 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.902 0.741 – 1.1 0.301 120 1173 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.863 0.69 – 1.08 0.194 92 909 exclusion phecode
528.5 Diseases of lips Digestive 1.01 0.927 – 1.09 0.863 614 6558 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.01 0.895 – 1.14 0.862 293 2971 exclusion phecode
528.7 Sialolithiasis Digestive 1.06 0.939 – 1.19 0.359 303 3034 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 0.97 0.913 – 1.03 0.324 1170 11838 exclusion phecode
529.1 Glossitis Digestive 0.914 0.808 – 1.03 0.152 285 2872 exclusion phecode
530 Diseases of esophagus Digestive 1.02 1.01 – 1.03 0.00124 32040 269532 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.02 1.01 – 1.03 0.000766 29954 262896 exclusion phecode
530.11 GERD Digestive 1.01 1 – 1.03 0.0517 21699 217582 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.05 1.02 – 1.08 0.00184 4995 49866 exclusion phecode
530.14 Reflux esophagitis Digestive 1.01 0.993 – 1.03 0.212 10044 100616 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.02 0.969 – 1.07 0.454 1608 16163 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 0.998 0.95 – 1.05 0.945 1786 17875 exclusion phecode
530.5 Disorders of esophageal motility Digestive 0.98 0.9 – 1.07 0.649 601 6138 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.1 0.933 – 1.3 0.25 145 1452 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.07 0.956 – 1.2 0.238 326 3305 exclusion phecode
530.9 Heartburn Digestive 1.06 1.01 – 1.11 0.0129 1997 20131 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.01 0.982 – 1.03 0.558 6779 68117 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.02 0.941 – 1.11 0.601 615 6090 exclusion phecode
531.2 Gastric ulcer Digestive 1.01 0.975 – 1.04 0.65 3903 39233 exclusion phecode
531.3 Duodenal ulcer Digestive 0.989 0.951 – 1.03 0.571 2863 28826 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.11 1 – 1.23 0.0429 401 4112 exclusion phecode
532 Dysphagia Digestive 1.05 1.02 – 1.08 0.000184 6131 61937 exclusion phecode
535 Gastritis and duodenitis Digestive 1.03 1.02 – 1.05 9.57e-07 26896 252042 exclusion phecode
535.1 Acute gastritis Digestive 0.999 0.939 – 1.06 0.966 1128 11387 exclusion phecode
535.2 Atrophic gastritis Digestive 1.11 1 – 1.24 0.0493 359 3542 exclusion phecode
535.6 Duodenitis Digestive 1.03 1.01 – 1.06 0.0141 7288 72951 exclusion phecode
535.8 Other specified gastritis Digestive 1.03 1.01 – 1.06 0.00685 7720 77589 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.08 0.901 – 1.29 0.415 115 1143 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.07 0.943 – 1.21 0.307 253 2478 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.05 1.01 – 1.09 0.0136 3255 32549 exclusion phecode
540 Appendiceal conditions Digestive 0.967 0.931 – 1 0.0848 2991 30042 exclusion phecode
540.1 Appendicitis Digestive 0.964 0.927 – 1 0.0712 2806 28166 exclusion phecode
540.11 Acute appendicitis Digestive 0.966 0.926 – 1.01 0.096 2522 25319 exclusion phecode
550 Abdominal hernia Digestive 1.01 1 – 1.03 0.0061 43384 273235 exclusion phecode
550.1 Inguinal hernia Digestive 1 0.987 – 1.02 0.621 15004 118484 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.03 1.01 – 1.04 0.000183 25386 230230 exclusion phecode
550.3 Femoral hernia Digestive 1 0.924 – 1.09 0.944 630 6283 exclusion phecode
550.4 Umbilical hernia Digestive 1.01 0.975 – 1.04 0.602 3552 35769 exclusion phecode
550.5 Ventral hernia Digestive 1.04 1 – 1.08 0.0463 3256 33020 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.01 0.983 – 1.05 0.38 4229 42934 exclusion phecode
555.1 Regional enteritis Digestive 0.99 0.941 – 1.04 0.715 1647 16761 exclusion phecode
555.2 Ulcerative colitis Digestive 1.03 0.994 – 1.07 0.0996 3029 30694 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 0.993 0.906 – 1.09 0.887 507 5178 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.08 1.01 – 1.15 0.0188 1001 10216 exclusion phecode
556.1 Ulceration of intestine Digestive 1.07 0.988 – 1.16 0.0937 636 6488 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.967 0.855 – 1.09 0.591 289 2897 exclusion phecode
557.1 Celiac disease Digestive 1.13 1.07 – 1.18 1.66e-06 1754 17742 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.03 1.01 – 1.05 0.000873 14851 149700 exclusion phecode
559 Ileostomy status Digestive 1.02 0.965 – 1.07 0.533 1568 15861 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.03 0.997 – 1.07 0.0723 3750 37828 exclusion phecode
560.1 Paralytic ileus Digestive 1.1 1 – 1.21 0.0463 484 4994 exclusion phecode
560.2 Impaction of intestine Digestive 1.03 0.903 – 1.17 0.692 259 2567 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.08 1 – 1.16 0.0404 793 8013 exclusion phecode
560.4 Other intestinal obstruction Digestive 1.03 0.99 – 1.06 0.159 3211 32274 exclusion phecode
561 Symptoms involving digestive system Digestive 1 0.987 – 1.02 0.688 15118 152208 exclusion phecode
561.1 Diarrhea Digestive 1.08 0.987 – 1.19 0.0932 449 4470 exclusion phecode
561.2 Flatulence Digestive 1.01 0.964 – 1.07 0.578 1618 16266 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1.01 0.996 – 1.02 0.176 25439 203884 exclusion phecode
562.1 Diverticulosis Digestive 1.01 0.996 – 1.02 0.179 25400 203835 exclusion phecode
563 Constipation Digestive 1 0.982 – 1.02 0.765 9865 99351 exclusion phecode
564 Functional digestive disorders Digestive 1.01 1 – 1.03 0.0445 20687 202414 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.02 0.991 – 1.05 0.184 5332 53392 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1 0.951 – 1.06 0.921 1559 15862 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.02 1 – 1.04 0.0172 14472 145762 exclusion phecode
565 Anal and rectal conditions Digestive 1.02 0.999 – 1.03 0.071 14068 142130 exclusion phecode
565.1 Anal and rectal polyp Digestive 1.02 0.999 – 1.05 0.0561 6985 70625 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.01 0.943 – 1.09 0.742 887 8971 exclusion phecode
568 Other disorders of peritoneum Digestive 1.02 0.983 – 1.06 0.296 3134 31437 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.01 0.977 – 1.05 0.462 2985 29893 exclusion phecode
569 Other disorders of intestine Digestive 1.01 0.977 – 1.04 0.563 3991 40321 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.07 0.89 – 1.27 0.49 138 1405 exclusion phecode
569.2 Gastrointestinal complications Digestive 0.918 0.834 – 1.01 0.0844 463 4668 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.07 1.03 – 1.11 0.00124 2806 28512 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.04 0.988 – 1.1 0.133 1607 16315 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.815 0.663 – 1 0.0505 105 1102 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.17 1.02 – 1.33 0.0196 242 2459 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.07 0.997 – 1.14 0.0622 932 9410 exclusion phecode
571.81 Portal hypertension Digestive 1.07 0.972 – 1.17 0.173 498 5090 exclusion phecode
572 Ascites (non malignant) Digestive 1.04 0.984 – 1.1 0.17 1463 14835 exclusion phecode
573 Other disorders of liver Digestive 1.03 0.978 – 1.09 0.251 1418 14347 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.03 0.812 – 1.3 0.816 72 924 exclusion phecode
573.3 Hepatomegaly Digestive 1.04 0.919 – 1.18 0.537 284 2836 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.05 0.975 – 1.12 0.204 859 8589 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.04 1 – 1.08 0.0476 3288 33291 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.18 1.02 – 1.36 0.0239 198 1991 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.01 0.998 – 1.03 0.0872 14992 150485 exclusion phecode
574.1 Cholelithiasis Digestive 1.02 0.998 – 1.03 0.0908 13007 130657 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.05 0.994 – 1.11 0.0789 1441 14523 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.02 0.987 – 1.05 0.277 5208 52363 exclusion phecode
574.2 Calculus of bile duct Digestive 0.988 0.948 – 1.03 0.582 2524 25210 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.01 0.971 – 1.05 0.604 2652 26482 exclusion phecode
575 Other biliary tract disease Digestive 1.03 0.998 – 1.07 0.0661 3701 37251 exclusion phecode
575.1 Cholangitis Digestive 0.989 0.899 – 1.09 0.816 472 4722 exclusion phecode
575.2 Obstruction of bile duct Digestive 1 0.927 – 1.08 0.986 741 7436 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 1.09 0.993 – 1.21 0.0687 442 4405 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.08 1.02 – 1.14 0.00561 1352 13624 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1 0.939 – 1.07 0.943 991 9974 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.916 0.816 – 1.03 0.142 329 3325 exclusion phecode
577 Diseases of pancreas Digestive 1.04 1 – 1.09 0.0448 2553 25631 exclusion phecode
577.1 Acute pancreatitis Digestive 1.04 0.995 – 1.09 0.0791 1911 19199 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.03 0.938 – 1.13 0.557 501 4968 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.02 0.908 – 1.14 0.791 346 3489 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.02 1 – 1.03 0.0104 19734 198962 exclusion phecode
578.1 Hematemesis Digestive 1.05 1 – 1.1 0.0355 1885 18839 exclusion phecode
578.2 Blood in stool Digestive 1.02 0.982 – 1.07 0.272 2507 25232 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.03 1.01 – 1.05 0.00409 12489 126197 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.01 0.977 – 1.04 0.692 5065 50949 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.04 0.982 – 1.09 0.194 1468 14937 exclusion phecode
579.2 Splenomegaly Digestive 1.06 0.954 – 1.18 0.282 388 4073 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.03 0.975 – 1.08 0.31 1580 15919 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.05 0.996 – 1.11 0.0673 1420 14682 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.03 0.966 – 1.1 0.349 972 10067 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.14 0.901 – 1.45 0.273 68 704 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.08 0.895 – 1.29 0.435 123 1310 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.01 0.94 – 1.09 0.774 811 8345 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.11 1.01 – 1.22 0.0373 447 4504 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.08 0.942 – 1.24 0.264 224 2364 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.1 0.961 – 1.26 0.166 230 2431 exclusion phecode
585 Renal failure Genitourinary 1.01 0.984 – 1.04 0.471 6526 66593 exclusion phecode
585.1 Acute renal failure Genitourinary 0.998 0.967 – 1.03 0.9 4284 43229 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.01 0.96 – 1.07 0.601 1365 14015 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1 0.963 – 1.05 0.823 2423 25260 exclusion phecode
585.31 Renal dialysis Genitourinary 1.05 0.953 – 1.16 0.317 432 4769 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.01 0.974 – 1.05 0.581 3153 32193 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.02 0.876 – 1.18 0.84 191 2002 exclusion phecode
586.11 Small kidney Genitourinary 1.01 0.864 – 1.19 0.869 163 1728 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 0.968 0.911 – 1.03 0.296 1187 12036 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1 0.792 – 1.26 0.997 74 759 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1 0.936 – 1.08 0.906 858 8784 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.08 0.959 – 1.22 0.204 290 3574 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.08 0.875 – 1.34 0.47 91 944 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 0.893 0.728 – 1.1 0.28 106 1108 exclusion phecode
590 Pyelonephritis Genitourinary 1.02 0.962 – 1.08 0.509 1271 12844 exclusion phecode
591 Urinary tract infection Genitourinary 1.01 0.987 – 1.03 0.519 11818 119050 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.04 1 – 1.08 0.0397 2814 28474 exclusion phecode
592.1 Cystitis Genitourinary 1.04 1 – 1.08 0.0391 2755 27866 exclusion phecode
592.11 Acute cystitis Genitourinary 1.05 0.875 – 1.25 0.624 127 1335 exclusion phecode
592.12 Chronic cystitis Genitourinary 1.03 0.96 – 1.11 0.407 836 8534 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.03 0.903 – 1.17 0.658 241 2417 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.92 0.782 – 1.08 0.313 158 1596 exclusion phecode
593 Hematuria Genitourinary 1.02 0.999 – 1.03 0.0698 15289 153863 exclusion phecode
594 Urinary calculus Genitourinary 1.01 0.985 – 1.04 0.405 6101 61384 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.02 0.981 – 1.06 0.332 3031 30499 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.03 0.953 – 1.11 0.455 726 7412 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.02 0.975 – 1.06 0.417 2301 23133 exclusion phecode
594.8 Renal colic Genitourinary 1.01 0.961 – 1.06 0.77 1974 19769 exclusion phecode
595 Hydronephrosis Genitourinary 0.99 0.943 – 1.04 0.685 1845 18662 exclusion phecode
596 Other disorders of bladder Genitourinary 1 0.982 – 1.03 0.744 9306 93463 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.01 0.966 – 1.06 0.581 1860 18725 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1.04 0.984 – 1.09 0.173 1588 15943 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.988 0.955 – 1.02 0.49 3748 37576 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.991 0.955 – 1.03 0.647 3178 31772 exclusion phecode
597.2 Urinary complications NEC Genitourinary 0.97 0.761 – 1.24 0.804 77 756 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.03 0.995 – 1.07 0.0941 3382 33819 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.08 0.958 – 1.22 0.209 290 2891 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1 0.986 – 1.02 0.82 17634 177282 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.962 0.815 – 1.14 0.65 156 1599 exclusion phecode
599.2 Retention of urine Genitourinary 1 0.974 – 1.03 0.984 6357 64017 exclusion phecode
599.3 Dysuria Genitourinary 1.04 0.978 – 1.11 0.217 1151 11522 exclusion phecode
599.4 Urinary incontinence Genitourinary 1 0.978 – 1.02 0.953 8412 84411 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 0.996 0.963 – 1.03 0.805 3818 38513 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.08 0.878 – 1.34 0.45 94 1001 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.06 0.818 – 1.37 0.662 58 599 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1.04 0.987 – 1.09 0.151 1827 18321 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.985 0.964 – 1.01 0.145 10412 83841 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 0.963 0.919 – 1.01 0.121 1962 19882 exclusion phecode
601.1 Prostatitis Genitourinary 0.993 0.941 – 1.05 0.8 1466 14909 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.947 0.823 – 1.09 0.447 216 2261 exclusion phecode
601.12 Chronic prostatitis Genitourinary 0.994 0.926 – 1.07 0.861 851 8659 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 1.19 0.915 – 1.54 0.198 58 570 exclusion phecode
601.4 Balanoposthitis Genitourinary 0.882 0.776 – 1 0.0545 277 2741 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.914 0.807 – 1.04 0.157 287 2895 exclusion phecode
602 Other disorders of prostate Genitourinary 0.926 0.873 – 0.983 0.0114 1263 12737 exclusion phecode
603 Other disorders of testis Genitourinary 1.01 0.961 – 1.05 0.79 2036 20681 exclusion phecode
603.1 Hydrocele Genitourinary 0.987 0.931 – 1.05 0.665 1260 12810 exclusion phecode
604 Disorders of penis Genitourinary 0.971 0.936 – 1.01 0.123 3167 31593 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.971 0.933 – 1.01 0.164 2632 26180 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 1.02 0.898 – 1.16 0.77 263 2671 exclusion phecode
608 Other disorders of male genital organs Genitourinary 1.01 0.973 – 1.05 0.539 2695 27102 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.887 0.759 – 1.04 0.132 192 2034 exclusion phecode
609.1 Infertility, male Genitourinary 0.928 0.721 – 1.19 0.558 60 616 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.874 0.729 – 1.05 0.148 149 1592 exclusion phecode
610 Benign mammary dysplasias Genitourinary 1.01 0.964 – 1.05 0.81 2392 24125 exclusion phecode
610.1 Cystic mastopathy Genitourinary 1.12 1.04 – 1.19 0.00143 888 8970 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 0.975 0.863 – 1.1 0.683 287 2967 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 0.952 0.839 – 1.08 0.443 289 2922 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 1.01 0.953 – 1.07 0.765 1350 13484 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.01 0.928 – 1.09 0.895 663 6751 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.988 0.936 – 1.04 0.663 1509 15242 exclusion phecode
611.1 Abnormal mammogram Genitourinary 1.07 0.817 – 1.41 0.614 55 559 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.984 0.932 – 1.04 0.576 1458 14734 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.961 0.895 – 1.03 0.267 857 8625 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.985 0.917 – 1.06 0.689 824 8245 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 0.824 0.642 – 1.06 0.127 67 705 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 1.05 1 – 1.11 0.0501 1584 16022 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.06 0.982 – 1.15 0.134 692 6995 exclusion phecode
613.5 Mastodynia Genitourinary 1.06 0.837 – 1.35 0.617 73 745 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 1.12 1.04 – 1.21 0.00386 680 6804 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1.06 0.94 – 1.18 0.362 316 3194 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.03 1 – 1.06 0.0539 5525 55624 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.04 0.994 – 1.08 0.0976 2462 24769 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.03 0.961 – 1.11 0.374 806 8105 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.1 0.847 – 1.42 0.483 61 593 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.06 0.957 – 1.17 0.261 409 4117 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.07 0.954 – 1.19 0.255 344 3424 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.956 0.838 – 1.09 0.498 267 2713 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.03 0.985 – 1.07 0.219 2509 25269 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.04 0.984 – 1.1 0.162 1276 12802 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.993 0.898 – 1.1 0.898 410 4147 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.99 0.917 – 1.07 0.802 733 7382 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.09 0.964 – 1.24 0.164 263 2655 exclusion phecode
615 Endometriosis Genitourinary 1.02 0.983 – 1.05 0.353 3926 39388 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.06 0.932 – 1.19 0.394 286 2948 exclusion phecode
618 Genital prolapse Genitourinary 0.994 0.975 – 1.01 0.547 11276 112778 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 1.01 0.989 – 1.04 0.274 7137 71257 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.967 0.939 – 0.996 0.0243 5202 51893 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.05 0.954 – 1.15 0.328 497 4959 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.03 0.951 – 1.12 0.448 657 6546 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1.02 0.995 – 1.04 0.134 8422 84776 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.957 0.885 – 1.04 0.276 710 7086 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 1.01 0.973 – 1.05 0.622 3196 32240 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.04 0.997 – 1.08 0.0725 2772 27834 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.01 0.956 – 1.06 0.842 1706 17148 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.05 0.992 – 1.11 0.0913 1296 13081 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 0.965 0.757 – 1.23 0.774 68 700 exclusion phecode
621 Endometrial hyperplasia Genitourinary 1.01 0.952 – 1.08 0.672 1084 10924 exclusion phecode
622 Polyp of female genital organs Genitourinary 1.01 0.992 – 1.03 0.219 10130 101623 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 1.01 0.983 – 1.03 0.579 7594 76215 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 1.05 1.02 – 1.09 0.0041 3334 33340 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1 0.946 – 1.06 0.908 1227 12348 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 1.03 0.954 – 1.11 0.476 766 7686 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.942 0.82 – 1.08 0.393 227 2273 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 1.05 0.952 – 1.17 0.312 421 4237 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.995 0.968 – 1.02 0.73 5669 56746 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.04 0.996 – 1.08 0.0775 2775 28027 exclusion phecode
625.1 Dyspareunia Genitourinary 1.05 0.988 – 1.12 0.118 1146 11616 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.01 0.992 – 1.03 0.309 15794 112253 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1 0.985 – 1.02 0.735 13793 107348 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 1.11 0.913 – 1.35 0.293 104 1083 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1.02 0.999 – 1.04 0.0586 9502 89743 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 1.02 0.969 – 1.06 0.517 1946 19327 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.98 0.947 – 1.01 0.252 3707 37196 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.991 0.943 – 1.04 0.706 1721 17429 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 1.02 0.869 – 1.21 0.77 157 1559 exclusion phecode
626.8 Infertility, female Genitourinary 1.08 1.02 – 1.14 0.00642 1342 13407 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 1 0.981 – 1.02 0.915 9971 100318 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 1.01 0.986 – 1.03 0.492 8683 87219 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.903 0.769 – 1.06 0.217 171 1777 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.972 0.911 – 1.04 0.375 1066 10655 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 0.94 0.834 – 1.06 0.315 303 3005 exclusion phecode
628 Ovarian cyst Genitourinary 1.03 1 – 1.06 0.04 4598 46329 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.01 0.981 – 1.04 0.47 5127 35916 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.06 0.994 – 1.12 0.077 1118 11148 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.06 0.948 – 1.19 0.302 326 3253 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1 0.956 – 1.05 0.927 1934 17160 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.979 0.912 – 1.05 0.568 849 8501 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.03 0.967 – 1.09 0.397 1241 12158 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1 0.958 – 1.04 0.983 2306 19723 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.973 0.894 – 1.06 0.525 603 6060 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.05 0.988 – 1.12 0.114 1067 10610 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 0.971 0.766 – 1.23 0.811 70 688 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.969 0.909 – 1.03 0.331 1096 10934 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.01 0.894 – 1.13 0.903 303 3021 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.28 1.11 – 1.47 0.000544 210 2117 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.19 1.01 – 1.39 0.0392 148 1501 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.05 0.987 – 1.11 0.126 1232 12268 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.983 0.94 – 1.03 0.457 2190 20563 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.741 0.569 – 0.966 0.0265 66 669 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.87 0.765 – 0.989 0.0339 274 2715 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.988 0.812 – 1.2 0.904 111 1115 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.02 0.876 – 1.18 0.84 190 1889 exclusion phecode
650 Normal delivery Pregnancy Complications 1 0.954 – 1.05 0.97 1890 18723 exclusion phecode
651 Multiple gestation Pregnancy Complications 0.993 0.887 – 1.11 0.897 338 3398 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1.01 0.958 – 1.06 0.754 1684 16301 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.985 0.932 – 1.04 0.609 1379 13468 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.09 0.867 – 1.38 0.455 72 725 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.983 0.951 – 1.02 0.298 4238 29051 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.935 0.763 – 1.15 0.515 108 1066 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.985 0.942 – 1.03 0.507 2234 18166 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.993 0.908 – 1.09 0.886 527 5243 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.969 0.94 – 0.999 0.0409 5224 29072 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.987 0.947 – 1.03 0.556 2507 20909 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.02 0.862 – 1.2 0.83 161 1606 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.911 0.801 – 1.04 0.16 259 2570 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1 0.774 – 1.3 0.989 63 614 exclusion phecode
679 Complications of in utero procedures Dermatologic 1.24 0.945 – 1.63 0.12 51 523 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.04 1.01 – 1.06 0.00372 6865 69556 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.04 0.956 – 1.14 0.341 541 5439 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.05 0.958 – 1.15 0.291 501 5028 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.04 1.01 – 1.07 0.0175 5227 52947 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.04 1.01 – 1.07 0.017 5234 53007 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.04 1.01 – 1.07 0.0147 5192 52590 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.08 0.995 – 1.18 0.0657 559 5791 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.11 1.05 – 1.18 0.000281 1221 12916 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.05 1 – 1.09 0.0487 2202 22158 exclusion phecode
686.3 Pilonidal cyst Dermatologic 0.983 0.901 – 1.07 0.69 562 5718 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.07 0.956 – 1.19 0.245 340 3507 exclusion phecode
687 Symptoms affecting skin Dermatologic 1.01 0.924 – 1.11 0.771 511 5279 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.05 0.998 – 1.09 0.0584 2029 20681 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 0.986 0.869 – 1.12 0.821 269 2710 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.978 0.793 – 1.21 0.832 92 1020 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.03 0.989 – 1.07 0.166 2756 27915 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.05 1.02 – 1.08 0.00331 4626 55417 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 1.12 0.874 – 1.44 0.365 61 691 exclusion phecode
691 Congenital anomalies of skin Dermatologic 1.2 0.984 – 1.46 0.0721 105 1162 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 1.03 0.955 – 1.11 0.445 756 9521 exclusion phecode
694.1 Vitiligo Dermatologic 0.829 0.623 – 1.1 0.201 58 579 exclusion phecode
694.2 Other dyschromia Dermatologic 1.05 0.965 – 1.15 0.251 564 7568 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.11 0.915 – 1.35 0.288 109 1129 exclusion phecode
695 Erythematous conditions Dermatologic 1.04 0.994 – 1.09 0.0885 2221 22931 exclusion phecode
695.1 Toxic erythema Dermatologic 1.08 0.89 – 1.31 0.435 105 1056 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.12 0.934 – 1.33 0.228 128 1297 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 1.14 0.871 – 1.49 0.338 52 539 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.1 0.866 – 1.41 0.424 69 697 exclusion phecode
695.3 Rosacea Dermatologic 1.09 0.967 – 1.23 0.155 275 2962 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.1 0.999 – 1.22 0.0526 392 3986 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.19 0.99 – 1.42 0.0644 125 1265 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.07 0.957 – 1.19 0.239 323 3301 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 0.97 0.897 – 1.05 0.435 725 7451 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1.1 0.962 – 1.27 0.157 220 2267 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.921 0.726 – 1.17 0.501 72 739 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.03 0.935 – 1.14 0.531 436 4502 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.975 0.932 – 1.02 0.263 2123 21676 exclusion phecode
696.4 Psoriasis Dermatologic 0.978 0.935 – 1.02 0.347 2072 21159 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.983 0.932 – 1.04 0.511 1572 16164 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.997 0.921 – 1.08 0.942 678 6834 exclusion phecode
697 Sarcoidosis Dermatologic 0.945 0.863 – 1.04 0.226 507 5196 exclusion phecode
698 Pruritus and related conditions Dermatologic 1.05 0.971 – 1.13 0.233 746 7548 exclusion phecode
700 Corns and callosities Dermatologic 1.02 0.896 – 1.15 0.798 269 2789 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.05 1.01 – 1.08 0.00576 3768 45100 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 1.01 0.797 – 1.28 0.934 76 836 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.08 1.03 – 1.13 0.00308 1735 22700 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 1.19 0.921 – 1.53 0.185 58 587 exclusion phecode
701.4 Keloid scar Dermatologic 1.08 0.923 – 1.26 0.339 180 2100 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 0.999 0.9 – 1.11 0.989 403 4417 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.12 0.889 – 1.41 0.339 80 974 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.11 1.08 – 1.15 1.69e-10 4021 52620 exclusion phecode
702.1 Actinic keratosis Dermatologic 1.22 1.17 – 1.28 3.15e-16 1714 24817 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 1.04 0.994 – 1.08 0.0892 2380 29632 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.01 0.898 – 1.12 0.93 323 3385 exclusion phecode
703.1 Ingrowing nail Dermatologic 1.05 0.978 – 1.12 0.188 927 9341 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 1.06 1.02 – 1.09 0.000307 5014 50990 exclusion phecode
704.1 Alopecia Dermatologic 0.935 0.771 – 1.13 0.493 113 1239 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.986 0.76 – 1.28 0.917 61 744 exclusion phecode
705 Disorders of sweat glands Dermatologic 1.01 0.882 – 1.16 0.86 223 2222 exclusion phecode
705.3 Hidradenitis Dermatologic 0.973 0.835 – 1.13 0.725 182 1819 exclusion phecode
705.8 Hyperhidrosis Dermatologic 0.99 0.907 – 1.08 0.824 556 5651 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1.06 1.03 – 1.08 2.32e-06 7874 80355 exclusion phecode
706.1 Acne Dermatologic 0.902 0.704 – 1.16 0.417 73 755 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1.06 1.04 – 1.08 6.22e-07 8335 84902 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.04 0.987 – 1.09 0.149 1843 18779 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.03 0.959 – 1.1 0.425 867 8682 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 1 0.966 – 1.04 0.914 3281 33073 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.06 0.97 – 1.17 0.188 485 4902 exclusion phecode
709.3 Systemic sclerosis Dermatologic 1.13 0.969 – 1.33 0.117 166 1686 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.16 0.894 – 1.5 0.267 61 630 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.993 0.953 – 1.03 0.741 2601 26145 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.08 0.993 – 1.18 0.0725 577 5816 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.1 1 – 1.2 0.0403 532 5380 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.05 0.905 – 1.22 0.519 185 1878 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.11 0.998 – 1.23 0.0549 380 3858 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 1.01 0.912 – 1.12 0.813 409 4090 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.05 0.937 – 1.19 0.377 317 3185 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.06 0.844 – 1.32 0.629 76 770 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.953 0.801 – 1.13 0.588 141 1449 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 0.912 0.712 – 1.17 0.467 63 648 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.02 0.988 – 1.05 0.225 4551 46543 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.02 0.992 – 1.06 0.134 4113 42102 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.03 0.973 – 1.08 0.343 1583 15983 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.16 0.952 – 1.42 0.138 107 1085 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.972 0.893 – 1.06 0.513 592 5967 exclusion phecode
716 Other arthropathies Musculoskeletal 1 0.993 – 1.02 0.437 35684 256139 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.04 1 – 1.08 0.0259 3336 33646 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.01 0.991 – 1.03 0.343 14846 149246 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.01 0.994 – 1.02 0.394 34225 253125 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.987 0.927 – 1.05 0.693 1088 10860 exclusion phecode
720 Spinal stenosis Musculoskeletal 0.988 0.954 – 1.02 0.494 3536 35533 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1.03 1 – 1.05 0.0292 7515 75211 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.04 1.01 – 1.07 0.0156 4834 48443 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.03 0.885 – 1.2 0.702 185 1830 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 1.12 0.999 – 1.25 0.0515 342 3378 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1 0.978 – 1.02 0.97 8616 86769 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.12 1.02 – 1.22 0.0155 499 4938 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.01 0.971 – 1.05 0.606 2712 27282 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.08 0.833 – 1.41 0.553 66 654 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.986 0.955 – 1.02 0.403 4240 42632 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 0.912 0.831 – 1 0.0537 506 4970 exclusion phecode
723.1 Torticollis Musculoskeletal 1.01 0.83 – 1.24 0.887 105 1027 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.03 0.984 – 1.08 0.198 1981 19775 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1.04 0.934 – 1.15 0.491 381 3883 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 1.03 0.925 – 1.14 0.616 384 3917 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.13 0.882 – 1.45 0.331 63 604 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.03 0.976 – 1.08 0.288 1564 15560 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.01 0.988 – 1.02 0.576 14092 141507 exclusion phecode
726.1 Enthesopathy Musculoskeletal 1.01 0.993 – 1.04 0.186 9203 92341 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.892 0.793 – 1 0.0554 317 3243 exclusion phecode
726.3 Bursitis Musculoskeletal 0.978 0.909 – 1.05 0.555 819 8271 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.996 0.972 – 1.02 0.776 7038 70854 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.01 0.965 – 1.05 0.808 2606 26469 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 1.04 0.85 – 1.26 0.723 102 991 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.974 0.937 – 1.01 0.171 2999 30050 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 1.02 0.939 – 1.12 0.585 565 5629 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.976 0.87 – 1.09 0.675 331 3387 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.05 0.883 – 1.25 0.582 137 1379 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.02 0.987 – 1.06 0.222 3474 35138 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.962 0.867 – 1.07 0.473 399 4000 exclusion phecode
728.7 Fasciitis Musculoskeletal 1.03 0.994 – 1.07 0.111 3604 36342 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.03 0.99 – 1.06 0.163 3286 33217 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 0.992 0.965 – 1.02 0.572 5765 58100 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.996 0.933 – 1.06 0.917 968 9761 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.939 0.763 – 1.15 0.55 98 976 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.92 0.809 – 1.05 0.206 261 2664 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.937 0.821 – 1.07 0.339 247 2518 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.904 0.82 – 0.997 0.0436 456 4537 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.848 0.731 – 0.985 0.0308 200 2007 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.908 0.697 – 1.18 0.475 57 561 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.999 0.949 – 1.05 0.955 1688 17173 exclusion phecode
733.2 Cyst of bone Musculoskeletal 0.951 0.842 – 1.07 0.423 295 3000 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.944 0.856 – 1.04 0.244 450 5182 exclusion phecode
733.6 Costochondritis Musculoskeletal 1.1 0.907 – 1.32 0.344 125 1229 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.982 0.925 – 1.04 0.565 1193 11896 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.05 0.864 – 1.27 0.641 116 1161 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1 0.981 – 1.02 0.841 9164 92639 exclusion phecode
735.1 Flat foot Musculoskeletal 0.941 0.804 – 1.1 0.448 181 1833 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 1.02 0.986 – 1.05 0.3 4831 48818 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1 0.956 – 1.05 0.911 1838 18578 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 1.04 0.982 – 1.09 0.203 1484 14974 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.998 0.973 – 1.02 0.899 6351 64147 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 0.972 0.922 – 1.02 0.294 1560 15653 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.09 0.953 – 1.25 0.211 237 2378 exclusion phecode
737 Curvature of spine Musculoskeletal 1.08 1.01 – 1.15 0.0193 1068 10869 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.06 0.991 – 1.13 0.0939 1003 10225 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.993 0.946 – 1.04 0.771 1823 18304 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.01 0.955 – 1.07 0.757 1447 14544 exclusion phecode
739 Contracture of joint Musculoskeletal 1.09 0.988 – 1.2 0.0861 471 4717 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.01 0.999 – 1.03 0.0712 26373 222646 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.01 0.995 – 1.03 0.162 16614 162328 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.02 0.998 – 1.04 0.0759 8573 85918 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.06 0.942 – 1.19 0.345 331 3374 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.11 1.02 – 1.21 0.0191 555 5687 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.02 0.999 – 1.04 0.0563 11606 117760 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.998 0.963 – 1.03 0.897 3413 34385 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 1.12 0.913 – 1.36 0.285 99 982 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 0.974 0.894 – 1.06 0.548 585 5926 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.99 0.83 – 1.18 0.912 145 1479 exclusion phecode
741.4 Joint effusions Musculoskeletal 1.01 0.955 – 1.07 0.729 1350 13657 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 0.903 0.736 – 1.11 0.328 105 1052 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.947 0.71 – 1.26 0.714 54 524 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.01 0.968 – 1.05 0.728 2744 27631 exclusion phecode
742.1 Loose body in joint Musculoskeletal 0.91 0.81 – 1.02 0.109 322 3231 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.995 0.811 – 1.22 0.96 95 944 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 0.968 0.882 – 1.06 0.497 479 4840 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 1.02 0.975 – 1.07 0.36 1925 19389 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.01 0.985 – 1.04 0.451 6922 72676 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.01 0.986 – 1.04 0.342 5815 61453 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.01 0.984 – 1.04 0.406 5229 53334 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1 0.912 – 1.1 0.994 494 5040 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.04 0.943 – 1.14 0.46 489 4985 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.982 0.911 – 1.06 0.627 772 7875 exclusion phecode
745 Pain in joint Musculoskeletal 1.01 0.989 – 1.04 0.313 7679 77024 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.978 0.939 – 1.02 0.272 2673 26840 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.975 0.935 – 1.02 0.239 2504 25157 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1.01 0.92 – 1.1 0.91 562 5633 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.05 0.916 – 1.2 0.486 228 2287 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.949 0.903 – 0.998 0.0432 1720 17295 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.01 0.859 – 1.19 0.88 163 1628 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.973 0.86 – 1.1 0.67 284 2923 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 1.07 0.99 – 1.16 0.0882 647 6611 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.983 0.872 – 1.11 0.776 304 3124 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.981 0.841 – 1.15 0.812 178 1821 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.13 1.02 – 1.27 0.0256 340 3464 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.13 0.987 – 1.3 0.0758 222 2186 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.16 0.956 – 1.41 0.132 104 1139 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.05 0.99 – 1.1 0.109 1444 14782 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.01 0.932 – 1.09 0.83 673 6738 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.03 0.933 – 1.14 0.554 443 4445 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.98 0.853 – 1.13 0.773 216 2140 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.07 0.994 – 1.15 0.0701 776 8070 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 1.1 0.992 – 1.22 0.071 383 4089 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.03 0.917 – 1.16 0.615 318 3230 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.993 0.885 – 1.11 0.9 320 3212 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.01 0.889 – 1.15 0.852 248 2482 exclusion phecode
752.11 Spina bifida Congenital Anomalies 1.06 0.92 – 1.22 0.42 203 2046 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.03 0.815 – 1.31 0.792 76 754 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.829 0.683 – 1.01 0.0583 124 1236 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.887 0.688 – 1.14 0.352 74 737 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.06 0.869 – 1.3 0.551 104 1061 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.03 0.927 – 1.14 0.614 393 4123 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.04 0.901 – 1.2 0.597 194 2019 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.01 0.856 – 1.19 0.906 155 1566 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.918 0.75 – 1.12 0.405 104 1037 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.05 0.959 – 1.14 0.303 559 5675 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.05 0.832 – 1.32 0.697 75 793 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.03 0.93 – 1.14 0.57 418 4210 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.976 0.812 – 1.17 0.798 137 1652 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.908 0.684 – 1.21 0.505 55 802 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.09 0.944 – 1.25 0.248 208 2095 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1 0.811 – 1.24 0.984 94 930 exclusion phecode
760 Back pain Symptoms 1.01 0.988 – 1.03 0.449 10715 107406 exclusion phecode
761 Cervicalgia Symptoms 0.993 0.945 – 1.04 0.793 1725 17327 exclusion phecode
764 Sciatica Symptoms 0.971 0.93 – 1.01 0.193 2287 22896 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.966 0.907 – 1.03 0.279 1121 11319 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.07 0.986 – 1.17 0.102 603 6077 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.996 0.927 – 1.07 0.92 823 8396 exclusion phecode
771.1 Swelling of limb Symptoms 0.988 0.958 – 1.02 0.467 4428 44519 exclusion phecode
772 Symptoms of the muscles Symptoms 1.06 0.975 – 1.15 0.172 626 6333 exclusion phecode
773 Pain in limb Symptoms 1.02 0.995 – 1.05 0.119 5962 59987 exclusion phecode
780 Hypothermia/Chills Symptoms 1.07 0.903 – 1.26 0.444 160 1646 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.973 0.926 – 1.02 0.275 1785 18033 exclusion phecode
782.3 Edema Symptoms 1.06 1.01 – 1.12 0.0298 1563 15789 exclusion phecode
782.6 Pallor and flushing Symptoms 1.12 0.961 – 1.31 0.145 167 1695 exclusion phecode
783 Fever of unknown origin Symptoms 0.976 0.943 – 1.01 0.159 3716 37655 exclusion phecode
785 Abdominal pain Symptoms 1.01 1 – 1.02 0.0248 38557 291645 exclusion phecode
788 Syncope and collapse Symptoms 1.03 1 – 1.05 0.0271 8686 87127 exclusion phecode
789 Nausea and vomiting Symptoms 1.04 1.02 – 1.06 0.000128 11079 111580 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 0.918 0.765 – 1.1 0.361 137 1445 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.06 0.842 – 1.33 0.627 82 809 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1 0.973 – 1.03 0.994 5997 60716 exclusion phecode
791 Gangrene Symptoms 0.905 0.824 – 0.993 0.0344 523 5277 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1.21 0.987 – 1.48 0.0666 92 933 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.05 0.874 – 1.26 0.616 124 1276 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.1 1 – 1.2 0.0424 536 5413 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.02 0.842 – 1.24 0.833 120 1173 exclusion phecode
797 Shock Symptoms 0.908 0.763 – 1.08 0.277 151 1486 exclusion phecode
797.1 Cardiogenic shock Symptoms 0.933 0.751 – 1.16 0.533 100 975 exclusion phecode
798 Malaise and fatigue Symptoms 1.01 0.975 – 1.05 0.556 3238 32926 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 0.978 0.896 – 1.07 0.614 571 5730 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.02 0.99 – 1.04 0.244 6767 67723 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.986 0.938 – 1.04 0.572 1743 17365 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.904 0.766 – 1.07 0.237 163 1616 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.03 0.987 – 1.08 0.166 2091 20902 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.964 0.893 – 1.04 0.344 732 7345 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.05 1 – 1.1 0.0405 2139 21317 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.07 1.02 – 1.12 0.00927 1775 17762 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 0.996 0.92 – 1.08 0.921 692 6915 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 1.02 0.996 – 1.04 0.0978 8011 80012 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1.03 0.976 – 1.08 0.307 1625 16248 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.02 0.993 – 1.05 0.139 5047 50359 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.04 0.989 – 1.1 0.119 1466 14674 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.976 0.94 – 1.01 0.189 3224 32310 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.04 0.985 – 1.1 0.152 1312 13065 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.07 0.993 – 1.15 0.0771 749 7462 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.06 0.995 – 1.12 0.071 1253 12539 exclusion phecode
817 Concussion Injuries & Poisonings 1.24 1.08 – 1.42 0.00187 240 2334 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.953 0.868 – 1.05 0.307 505 4991 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.03 0.99 – 1.07 0.149 2864 28674 exclusion phecode
823 Torus fracture Injuries & Poisonings 1.04 0.986 – 1.09 0.152 1624 16208 exclusion phecode
830 Dislocation Injuries & Poisonings 1.03 0.983 – 1.08 0.217 2015 20234 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 1 0.983 – 1.02 0.999 14650 147201 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 1.04 0.952 – 1.14 0.372 509 5075 exclusion phecode
840 Sprains and strains Injuries & Poisonings 1 0.911 – 1.11 0.925 452 4531 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.05 1.02 – 1.08 0.000551 4955 50711 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.02 0.856 – 1.21 0.835 136 1512 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 0.981 0.892 – 1.08 0.694 466 4808 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.02 0.968 – 1.07 0.492 1722 17455 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.98 0.922 – 1.04 0.515 1182 11901 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.01 0.976 – 1.05 0.49 3014 30372 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.04 0.998 – 1.07 0.0674 3105 31361 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.01 0.779 – 1.32 0.916 62 662 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.04 1.01 – 1.08 0.0231 3375 33767 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.04 0.917 – 1.19 0.527 265 2619 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1.05 0.907 – 1.21 0.518 193 1879 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.04 0.998 – 1.08 0.0602 2795 28007 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.09 0.945 – 1.25 0.245 212 2105 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.937 0.722 – 1.22 0.626 66 664 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 0.971 0.94 – 1 0.0886 3920 39293 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.22 0.928 – 1.6 0.155 53 510 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.09 0.885 – 1.34 0.419 89 866 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.998 0.853 – 1.17 0.984 170 1729 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 0.946 0.858 – 1.04 0.261 450 4557 exclusion phecode
873 Broken tooth Injuries & Poisonings 0.946 0.824 – 1.09 0.432 224 2210 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 0.959 0.818 – 1.12 0.605 162 1666 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 0.996 0.846 – 1.17 0.957 155 1517 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.01 0.952 – 1.07 0.767 1266 12718 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.05 1.02 – 1.09 0.00236 4085 41042 exclusion phecode
916 Contusion Injuries & Poisonings 1.04 0.984 – 1.1 0.158 1388 13980 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.965 0.824 – 1.13 0.654 174 1754 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.21 1.07 – 1.36 0.00273 273 3738 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 1.29 1.1 – 1.5 0.00156 166 2421 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.02 0.976 – 1.07 0.346 1974 20190 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.858 0.742 – 0.992 0.0392 203 2159 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.04 0.843 – 1.28 0.731 97 1001 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.04 0.951 – 1.14 0.391 535 5314 exclusion phecode
947 Urticaria Injuries & Poisonings 1.02 0.913 – 1.13 0.753 358 3582 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.14 1.02 – 1.26 0.0157 378 3877 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.09 0.987 – 1.2 0.0892 405 4068 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.945 0.83 – 1.08 0.392 256 2580 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.941 0.855 – 1.04 0.211 476 4763 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 0.975 0.731 – 1.3 0.861 53 533 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.831 0.648 – 1.07 0.147 71 718 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.999 0.983 – 1.01 0.869 17193 175014 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.992 0.976 – 1.01 0.37 15056 153257 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.04 0.943 – 1.16 0.403 405 4036 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.02 0.95 – 1.1 0.566 829 8418 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.06 0.947 – 1.18 0.324 350 3571 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.03 0.924 – 1.15 0.572 343 3508 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.02 0.888 – 1.18 0.737 213 2172 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1 0.883 – 1.14 0.949 270 2728 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.04 0.912 – 1.18 0.577 264 2670 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.983 0.957 – 1.01 0.216 5836 58886 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.06 0.998 – 1.13 0.0592 1082 11056 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.07 0.974 – 1.18 0.16 463 4656 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.944 – 1.16 0.381 390 3930 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.03 0.941 – 1.13 0.495 487 4967 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1 0.917 – 1.1 0.96 558 5634 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.02 0.971 – 1.07 0.464 1887 19031 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.939 0.804 – 1.1 0.42 187 1859 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.02 0.899 – 1.16 0.737 255 2634 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.98 0.78 – 1.23 0.865 80 833 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.26 1.03 – 1.54 0.022 105 1048 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.959 0.773 – 1.19 0.7 97 971 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.974 0.758 – 1.25 0.837 63 620 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.997 0.751 – 1.32 0.983 54 560 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.1 0.958 – 1.26 0.179 224 2258 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.02 0.945 – 1.11 0.566 676 6763 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.887 0.763 – 1.03 0.117 195 1943 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.21 0.934 – 1.56 0.151 61 601 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.28 1.04 – 1.57 0.0177 100 1013 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.78 0.632 – 0.963 0.021 108 1090 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.993 0.793 – 1.25 0.954 84 857 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.01 0.968 – 1.05 0.76 2890 29801 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 0.994 0.956 – 1.03 0.749 2861 29032 exclusion phecode
994.2 Sepsis Injuries & Poisonings 0.994 0.956 – 1.03 0.749 2861 29032 exclusion phecode
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