Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Skin cancer Michigan Genomics Initiative (MGI) PheWAS analysis

Skin cancer — Michigan Genomics Initiative (MGI) PRS PheWAS

PRS model
PRS ID prsweb-phecode172-ukbb-saige-hrc-x172-prs-cs-mgi-20200608Legacy PRS-CSPRS-CSUKB GWAS (PheCode)

Evaluation cohort: Michigan Genomics Initiative (MGI).

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260 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 0.975 0.934 – 1.02 0.245 2317 23065 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.02 0.957 – 1.08 0.558 1090 10875 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.02 0.955 – 1.1 0.519 896 8939 all phecode
008.6 Viral Enteritis Infectious Diseases 0.908 0.834 – 0.988 0.0251 590 5900 all phecode
010 Tuberculosis Infectious Diseases 0.873 0.751 – 1.01 0.0762 195 1948 all phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.815 0.645 – 1.03 0.0868 73 722 all phecode
038 Septicemia Infectious Diseases 0.957 0.914 – 1 0.0579 2043 20052 all phecode
038.1 Gram negative septicemia Infectious Diseases 0.991 0.901 – 1.09 0.856 459 4559 all phecode
038.2 Gram positive septicemia Infectious Diseases 0.858 0.738 – 0.997 0.0453 184 1840 all phecode
038.3 Bacteremia Infectious Diseases 0.957 0.895 – 1.02 0.197 955 9489 all phecode
041 Bacterial infection NOS Infectious Diseases 0.972 0.942 – 1 0.0733 4641 32299 all phecode
041.1 Staphylococcus infections Infectious Diseases 0.955 0.903 – 1.01 0.105 1390 13828 all phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 0.912 0.844 – 0.986 0.0213 714 7071 all phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 0.995 0.916 – 1.08 0.905 639 6376 all phecode
041.2 Streptococcus infection Infectious Diseases 0.955 0.901 – 1.01 0.112 1316 13131 all phecode
041.21 Rheumatic fever / chorea Infectious Diseases 0.992 0.858 – 1.15 0.915 205 2047 all phecode
041.4 E. coli Infectious Diseases 0.984 0.921 – 1.05 0.644 949 9462 all phecode
041.8 H. pylori Infectious Diseases 0.96 0.827 – 1.11 0.591 190 1892 all phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 0.978 0.855 – 1.12 0.748 228 2265 all phecode
053 Herpes zoster Infectious Diseases 0.966 0.909 – 1.03 0.255 1184 11746 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.912 0.774 – 1.07 0.269 166 1655 all phecode
054 Herpes simplex Infectious Diseases 0.98 0.924 – 1.04 0.494 1235 12278 all phecode
070 Viral hepatitis Infectious Diseases 0.997 0.921 – 1.08 0.942 661 6584 all phecode
070.1 Viral hepatitis A Infectious Diseases 0.883 0.685 – 1.14 0.334 67 660 all phecode
070.2 Viral hepatitis B Infectious Diseases 0.966 0.824 – 1.13 0.666 162 1620 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.01 0.915 – 1.11 0.851 439 4366 all phecode
070.4 Chronic hepatitis Infectious Diseases 0.973 0.827 – 1.14 0.739 161 1610 all phecode
070.9 Hepatitis NOS Infectious Diseases 1 0.936 – 1.07 0.97 924 9231 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.03 0.858 – 1.25 0.727 122 1220 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.971 0.788 – 1.2 0.786 95 950 all phecode
078 Viral warts & HPV Infectious Diseases 0.99 0.951 – 1.03 0.631 2651 24185 all phecode
079 Viral infection Infectious Diseases 1.03 0.999 – 1.06 0.0545 5061 29504 all phecode
079.1 Varicella infection Infectious Diseases 1.08 1.04 – 1.12 7.05e-05 2940 25647 all phecode
079.2 Infectious mononucleosis Infectious Diseases 1.01 0.876 – 1.17 0.873 213 2093 all phecode
079.9 Viremia, NOS Infectious Diseases 1 0.918 – 1.09 0.998 579 5713 all phecode
080 Postoperative infection Infectious Diseases 0.982 0.943 – 1.02 0.385 2586 25769 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 0.917 0.867 – 0.971 0.0027 1364 13616 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.988 0.913 – 1.07 0.758 700 6990 all phecode
1000 Burns Injuries & Poisonings 0.935 0.861 – 1.01 0.107 638 6350 all phecode
1001 Foreign body injury Injuries & Poisonings 0.976 0.935 – 1.02 0.253 2372 22762 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 0.983 0.953 – 1.01 0.269 4830 32603 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 0.999 0.94 – 1.06 0.98 1136 11344 all phecode
1005 Other symptoms Injuries & Poisonings 0.986 0.961 – 1.01 0.272 7724 30626 all phecode
1006 Crushing injury Injuries & Poisonings 0.942 0.824 – 1.08 0.385 245 2437 all phecode
1007 Injury to blood vessels Injuries & Poisonings 1.04 0.938 – 1.15 0.46 411 4106 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 0.949 0.887 – 1.02 0.133 934 9331 all phecode
1009 Injury, NOS Injuries & Poisonings 0.986 0.963 – 1.01 0.226 9284 29063 all phecode
1010 Other tests Injuries & Poisonings 0.972 0.953 – 0.992 0.00605 19027 19331 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.976 0.949 – 1 0.0879 5922 32336 all phecode
1012 Late effect Injuries & Poisonings 0.94 0.873 – 1.01 0.102 792 7909 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 0.973 0.933 – 1.01 0.196 2459 23709 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.05 0.903 – 1.23 0.516 177 1770 all phecode
1015 Effects of other external causes Injuries & Poisonings 1.02 0.99 – 1.05 0.203 5744 32595 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 0.984 0.942 – 1.03 0.473 2208 21537 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.01 0.971 – 1.06 0.549 2379 23308 all phecode
110.1 Dermatophytosis Infectious Diseases 1.01 0.969 – 1.06 0.572 2164 21163 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.996 0.94 – 1.06 0.888 1264 12489 all phecode
110.12 Althete's foot Infectious Diseases 1.03 0.946 – 1.12 0.514 593 5884 all phecode
110.13 Dermatophytosis of the body Infectious Diseases 1.01 0.925 – 1.1 0.852 570 5682 all phecode
110.2 Dermatomycoses Infectious Diseases 0.948 0.838 – 1.07 0.405 283 2812 all phecode
1100 Family history Injuries & Poisonings 1.05 0.916 – 1.21 0.478 222 2220 all phecode
112 Candidiasis Infectious Diseases 1.01 0.976 – 1.05 0.462 2931 25310 all phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.02 0.934 – 1.11 0.668 546 5450 all phecode
117 Mycoses Infectious Diseases 0.947 0.862 – 1.04 0.263 494 4925 all phecode
117.1 Histoplasmosis Infectious Diseases 1.01 0.788 – 1.29 0.944 66 660 all phecode
117.4 Aspergillosis Infectious Diseases 0.845 0.691 – 1.03 0.102 105 1045 all phecode
130 Spirochetal infection Infectious Diseases 0.997 0.828 – 1.2 0.975 118 1177 all phecode
130.1 Lyme disease Infectious Diseases 1.07 0.86 – 1.33 0.54 86 860 all phecode
132 Infestation (lice, mites) Infectious Diseases 0.837 0.703 – 0.996 0.0452 146 1460 all phecode
134 Helminthiases Infectious Diseases 0.937 0.708 – 1.24 0.65 54 540 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.959 0.919 – 1 0.048 2438 24314 all phecode
145 Cancer of mouth Neoplasms 1 0.945 – 1.06 0.929 1182 11759 all phecode
145.1 Cancer of lip Neoplasms 1.15 0.906 – 1.45 0.256 69 690 all phecode
145.2 Cancer of tongue Neoplasms 0.955 0.875 – 1.04 0.306 550 5486 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.14 1.01 – 1.28 0.0316 310 3093 all phecode
145.4 Cancer of the gums Neoplasms 0.855 0.718 – 1.02 0.0772 143 1419 all phecode
145.5 Cancer of the mouth floor Neoplasms 0.903 0.773 – 1.05 0.193 173 1723 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.969 0.911 – 1.03 0.307 1124 11202 all phecode
149.1 Cancer of oropharynx Neoplasms 0.855 0.758 – 0.964 0.0107 291 2892 all phecode
149.2 Cancer of nasopharynx Neoplasms 0.803 0.645 – 0.999 0.049 87 855 all phecode
149.3 Cancer of hypopharynx Neoplasms 0.946 0.748 – 1.2 0.642 68 680 all phecode
149.4 Cancer of larynx Neoplasms 0.96 0.857 – 1.07 0.474 332 3314 all phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 0.984 0.899 – 1.08 0.732 505 5041 all phecode
149.9 Cancer of of nasal cavities Neoplasms 1.01 0.873 – 1.16 0.931 208 2067 all phecode
150 Cancer of esophagus Neoplasms 0.903 0.811 – 1 0.0598 378 3776 all phecode
151 Cancer of stomach Neoplasms 0.917 0.829 – 1.01 0.0941 430 4292 all phecode
153 Colorectal cancer Neoplasms 1.03 0.969 – 1.09 0.363 1196 11882 all phecode
153.2 Colon cancer Neoplasms 1.01 0.948 – 1.09 0.674 941 9327 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.01 0.931 – 1.09 0.834 669 6663 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.933 0.843 – 1.03 0.183 418 4180 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.949 0.841 – 1.07 0.399 285 2850 all phecode
157 Pancreatic cancer Neoplasms 1 0.906 – 1.1 0.999 430 4292 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.976 0.923 – 1.03 0.386 1369 13455 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.06 0.986 – 1.14 0.114 779 7785 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.931 0.796 – 1.09 0.371 183 1830 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.06 0.892 – 1.27 0.488 133 1330 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.11 0.977 – 1.25 0.111 255 2550 all phecode
164 Cancer of intrathoracic organs Neoplasms 0.892 0.731 – 1.09 0.258 111 1110 all phecode
165 Cancer within the respiratory system Neoplasms 1.03 0.96 – 1.1 0.444 945 9436 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.02 0.949 – 1.09 0.627 874 8724 all phecode
170 Cancer of bone and connective tissue Neoplasms 1.04 0.986 – 1.09 0.151 1538 15304 all phecode
170.1 Bone cancer Neoplasms 0.981 0.905 – 1.06 0.63 668 6660 all phecode
170.2 Cancer of connective tissue Neoplasms 1.04 0.981 – 1.11 0.174 1097 10941 all phecode
172 Skin cancer Neoplasms 1.34 1.31 – 1.38 2.94e-98 7099 27878 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.38 1.33 – 1.44 3.56e-55 2701 21867 all phecode
172.11 Melanomas of skin Neoplasms 1.38 1.32 – 1.44 1.18e-53 2624 21526 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1.37 1.33 – 1.42 1.6e-96 5888 25669 all phecode
172.21 Basal cell carcinoma Neoplasms 1.57 1.5 – 1.63 2.34e-107 2988 20068 all phecode
172.22 Squamous cell carcinoma Neoplasms 1.34 1.28 – 1.41 2.28e-33 1917 14585 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.46 1.37 – 1.55 1.27e-34 1215 10290 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.21 1.15 – 1.27 8.25e-13 1575 15093 all phecode
174 Breast cancer Neoplasms 0.971 0.932 – 1.01 0.175 2694 13131 all phecode
174.1 Breast cancer [female] Neoplasms 0.977 0.936 – 1.02 0.288 2605 12548 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.982 0.94 – 1.02 0.396 2565 12510 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.965 0.838 – 1.11 0.621 206 2051 all phecode
175 Acquired absence of breast Neoplasms 0.923 0.864 – 0.986 0.0177 978 9172 all phecode
180 Cervical cancer and dysplasia Neoplasms 0.966 0.909 – 1.03 0.272 1182 10494 all phecode
180.1 Cervical cancer Neoplasms 1 0.909 – 1.11 0.928 430 4300 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.955 0.888 – 1.03 0.209 857 7886 all phecode
182 Malignant neoplasm of uterus Neoplasms 0.954 0.88 – 1.03 0.255 643 6390 all phecode
184 Cancer of other female genital organs Neoplasms 1.02 0.951 – 1.09 0.62 910 8957 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.04 0.947 – 1.14 0.43 491 4888 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.03 0.93 – 1.15 0.538 367 3659 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.974 0.891 – 1.06 0.565 526 5253 all phecode
185 Cancer of prostate Neoplasms 0.926 0.884 – 0.971 0.00141 2432 8825 all phecode
187 Cancer of other male genital organs Neoplasms 0.953 0.84 – 1.08 0.454 276 2723 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.812 0.652 – 1.01 0.0634 96 960 all phecode
187.2 Malignant neoplasm of testis Neoplasms 1.08 0.907 – 1.28 0.402 144 1387 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.962 0.923 – 1 0.0649 2552 20553 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.969 0.915 – 1.03 0.289 1261 12588 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.946 0.889 – 1.01 0.0821 1083 10823 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1 0.864 – 1.16 0.984 202 2010 all phecode
189.2 Cancer of bladder Neoplasms 0.94 0.892 – 0.991 0.0208 1575 13516 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.94 0.89 – 0.993 0.0272 1456 12558 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.943 0.867 – 1.03 0.175 601 5841 all phecode
190 Cancer of eye Neoplasms 1.23 1.02 – 1.49 0.03 114 1125 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.983 0.918 – 1.05 0.626 904 9040 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1.02 0.935 – 1.11 0.702 580 5800 all phecode
191.11 Cancer of brain Neoplasms 1 0.916 – 1.1 0.929 483 4830 all phecode
193 Thyroid cancer Neoplasms 0.961 0.894 – 1.03 0.282 798 7953 all phecode
194 Cancer of other endocrine glands Neoplasms 0.961 0.839 – 1.1 0.563 221 2207 all phecode
195 Cancer, suspected or other Neoplasms 1.08 1.05 – 1.1 1.13e-09 12134 23141 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.08 1.05 – 1.11 1.82e-10 11693 23098 all phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1.07 0.999 – 1.14 0.0532 970 8963 all phecode
196 Radiotherapy Neoplasms 1.05 1 – 1.1 0.0497 2067 15612 all phecode
197 Chemotherapy Neoplasms 1.04 1.01 – 1.08 0.0229 4051 21210 all phecode
198 Secondary malignant neoplasm Neoplasms 1.06 1.03 – 1.09 0.000309 4986 21474 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.08 1.04 – 1.12 5.1e-05 3156 19844 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.04 0.975 – 1.12 0.219 903 8847 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.02 0.946 – 1.1 0.592 725 7166 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.05 0.966 – 1.14 0.261 643 6395 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.08 0.99 – 1.18 0.0823 545 5421 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.02 0.948 – 1.11 0.555 712 6962 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.2 1.06 – 1.35 0.00321 287 2752 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.04 1 – 1.07 0.0233 4947 22823 all phecode
199.4 Neurofibromatosis Neoplasms 0.915 0.714 – 1.17 0.481 72 720 all phecode
200 Myeloproliferative disease Neoplasms 0.964 0.899 – 1.03 0.306 886 8851 all phecode
200.1 Polycythemia vera Neoplasms 0.964 0.819 – 1.13 0.655 161 1610 all phecode
201 Hodgkin's disease Neoplasms 1.1 0.93 – 1.3 0.262 138 1373 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.997 0.942 – 1.06 0.913 1308 13070 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1 0.941 – 1.06 0.989 1141 11402 all phecode
202.21 Nodular lymphoma Neoplasms 1.01 0.935 – 1.1 0.726 632 6320 all phecode
202.22 Reticulosarcoma Neoplasms 0.929 0.784 – 1.1 0.4 137 1355 all phecode
202.24 Large cell lymphoma Neoplasms 0.953 0.799 – 1.14 0.593 132 1300 all phecode
204 Leukemia Neoplasms 1.03 0.942 – 1.12 0.543 545 5450 all phecode
204.1 Lymphoid leukemia Neoplasms 1.02 0.877 – 1.18 0.802 187 1870 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.931 0.71 – 1.22 0.607 58 580 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.05 0.881 – 1.25 0.581 136 1350 all phecode
204.2 Myeloid leukemia Neoplasms 0.931 0.807 – 1.07 0.324 206 2060 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.87 0.722 – 1.05 0.141 124 1240 all phecode
204.4 Multiple myeloma Neoplasms 1.13 0.97 – 1.31 0.118 180 1795 all phecode
208 Benign neoplasm of colon Neoplasms 1 0.976 – 1.03 0.971 8098 29324 all phecode
209 Neuroendocrine tumors Neoplasms 1.12 0.973 – 1.29 0.116 222 2220 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.998 0.948 – 1.05 0.953 1584 15798 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.98 0.953 – 1.01 0.166 5807 30296 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.01 0.954 – 1.06 0.84 1556 15533 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.972 0.919 – 1.03 0.31 1405 13304 all phecode
214 Lipoma Neoplasms 0.998 0.938 – 1.06 0.951 1117 11124 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.02 0.945 – 1.11 0.581 681 6793 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.997 0.963 – 1.03 0.87 3594 32904 all phecode
216 Benign neoplasm of skin Neoplasms 1.09 1.06 – 1.11 1.07e-11 9073 29036 all phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 1.09 0.907 – 1.31 0.356 111 1093 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.13 1.06 – 1.2 0.000115 1150 11417 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.11 1.04 – 1.18 0.00118 1063 10579 all phecode
218 Benign neoplasm of uterus Neoplasms 0.989 0.953 – 1.03 0.571 3552 13845 all phecode
218.1 Uterine leiomyoma Neoplasms 0.986 0.934 – 1.04 0.599 1506 13465 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.977 0.938 – 1.02 0.273 2824 13698 all phecode
220 Benign neoplasm of ovary Neoplasms 0.968 0.899 – 1.04 0.399 763 7571 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.05 0.992 – 1.1 0.0947 1666 12074 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.856 0.8 – 0.916 6.29e-06 954 9116 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.03 0.974 – 1.09 0.314 1547 11080 all phecode
224 Benign neoplasm of eye Neoplasms 1.03 0.941 – 1.13 0.519 511 5062 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.01 0.918 – 1.12 0.783 429 4230 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1 0.94 – 1.07 0.924 1039 10379 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1 0.934 – 1.08 0.905 817 8160 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.953 0.833 – 1.09 0.48 242 2420 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.96 0.902 – 1.02 0.206 1082 10810 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.992 0.938 – 1.05 0.764 1387 13870 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.959 0.863 – 1.06 0.431 375 3745 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.974 0.898 – 1.06 0.517 644 6434 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.15 1.03 – 1.27 0.0117 373 3724 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.03 0.981 – 1.09 0.21 1517 15150 all phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 1.09 1.01 – 1.17 0.0175 849 8478 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.03 1 – 1.06 0.0318 6631 31223 all phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 1.04 1.01 – 1.07 0.0178 4904 29712 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.951 0.883 – 1.02 0.184 767 7647 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.97 0.929 – 1.01 0.181 2274 18240 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.981 0.933 – 1.03 0.433 1795 16440 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.934 0.876 – 0.996 0.0385 1017 10065 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.995 0.935 – 1.06 0.886 1075 10635 all phecode
242.1 Graves' disease Endocrine/metabolic 0.967 0.872 – 1.07 0.528 399 3965 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 0.882 0.717 – 1.08 0.231 98 978 all phecode
242.3 Exophthalmos Endocrine/metabolic 0.879 0.768 – 1.01 0.0606 245 2447 all phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.85 0.699 – 1.03 0.103 116 1160 all phecode
244 Hypothyroidism Endocrine/metabolic 0.944 0.917 – 0.97 4.86e-05 6448 27183 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.972 0.921 – 1.03 0.312 1421 14153 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.953 0.888 – 1.02 0.188 853 8502 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.94 0.914 – 0.968 3.14e-05 5996 26719 all phecode
245 Thyroiditis Endocrine/metabolic 0.957 0.878 – 1.04 0.32 574 5720 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.948 0.86 – 1.04 0.278 463 4617 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.944 0.856 – 1.04 0.249 456 4533 all phecode
246 Other disorders of thyroid Endocrine/metabolic 0.936 0.907 – 0.966 3.82e-05 5018 25158 all phecode
246.2 Thyroid cyst Endocrine/metabolic 1.06 0.857 – 1.32 0.574 83 804 all phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 0.967 0.887 – 1.05 0.449 568 5651 all phecode
249 Secondary diabetes mellitus Endocrine/metabolic 0.942 0.87 – 1.02 0.145 686 6849 all phecode
250 Diabetes mellitus Endocrine/metabolic 0.948 0.926 – 0.97 7.95e-06 10115 27568 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.899 0.843 – 0.958 0.00113 1053 10521 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.851 0.675 – 1.07 0.171 80 792 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.911 0.796 – 1.04 0.178 235 2346 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.922 0.816 – 1.04 0.19 280 2800 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 0.957 0.837 – 1.09 0.522 238 2372 all phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 1.14 0.885 – 1.47 0.308 70 690 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.941 0.916 – 0.967 1.26e-05 7035 26169 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.736 0.608 – 0.892 0.00177 120 1200 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.964 0.906 – 1.02 0.24 1133 11056 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.98 0.912 – 1.05 0.584 826 8208 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 0.96 0.909 – 1.01 0.144 1419 13969 all phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 0.953 0.869 – 1.04 0.305 513 5077 all phecode
250.3 Insulin pump user Endocrine/metabolic 0.968 0.923 – 1.02 0.184 1884 17814 all phecode
250.4 Abnormal glucose Endocrine/metabolic 0.956 0.928 – 0.985 0.00295 5404 26451 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.952 0.9 – 1.01 0.0905 1326 13130 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.958 0.928 – 0.989 0.00748 4736 25883 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.03 0.819 – 1.3 0.802 78 747 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.964 0.906 – 1.03 0.241 1137 11335 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.971 0.904 – 1.04 0.421 821 8168 all phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 0.941 0.865 – 1.02 0.163 595 5901 all phecode
251.1 Hypoglycemia Endocrine/metabolic 0.939 0.869 – 1.01 0.112 702 7015 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1 0.956 – 1.05 0.879 1807 17879 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1 0.951 – 1.05 0.991 1656 16459 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.946 0.853 – 1.05 0.294 393 3922 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.988 0.913 – 1.07 0.76 691 6893 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.963 0.833 – 1.11 0.613 205 2041 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.17 0.926 – 1.48 0.186 72 720 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.09 0.937 – 1.27 0.266 184 1840 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.891 0.698 – 1.14 0.353 70 694 all phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 0.843 0.686 – 1.04 0.107 92 899 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.07 0.859 – 1.34 0.535 93 925 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.975 0.918 – 1.03 0.398 1186 11860 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.04 0.927 – 1.17 0.502 290 2886 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.09 0.928 – 1.29 0.285 144 1440 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.12 0.922 – 1.36 0.253 106 1057 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.95 0.864 – 1.05 0.292 477 4758 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.94 0.852 – 1.04 0.213 451 4496 all phecode
256 Ovarian dysfunction Endocrine/metabolic 0.917 0.854 – 0.985 0.017 859 8184 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.931 0.851 – 1.02 0.119 544 5436 all phecode
257 Testicular dysfunction Endocrine/metabolic 0.98 0.91 – 1.06 0.603 747 7455 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.984 0.912 – 1.06 0.667 725 7234 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.11 0.86 – 1.44 0.415 66 660 all phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.817 0.655 – 1.02 0.0724 92 920 all phecode
259 Other endocrine disorders Endocrine/metabolic 1 0.931 – 1.08 0.93 759 7562 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1 0.958 – 1.04 0.993 2353 22279 all phecode
260.1 Cachexia Endocrine/metabolic 0.89 0.78 – 1.01 0.0809 239 2388 all phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 0.994 0.94 – 1.05 0.83 1363 13589 all phecode
260.22 Nutritional marasmus Endocrine/metabolic 0.986 0.892 – 1.09 0.792 413 4130 all phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.02 0.931 – 1.12 0.665 509 5051 all phecode
260.6 Anorexia Endocrine/metabolic 0.979 0.905 – 1.06 0.595 677 6722 all phecode
261 Vitamin deficiency Endocrine/metabolic 0.96 0.932 – 0.988 0.00529 5614 30157 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.948 0.874 – 1.03 0.201 649 6482 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.957 0.928 – 0.985 0.00344 5264 29859 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.964 0.898 – 1.03 0.312 854 8532 all phecode
263 Other nutritional deficiency Endocrine/metabolic 0.941 0.85 – 1.04 0.243 412 4113 all phecode
264 Lack of normal physiological development Endocrine/metabolic 1.08 0.925 – 1.25 0.342 175 1735 all phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.04 0.84 – 1.28 0.733 95 950 all phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 0.894 0.689 – 1.16 0.402 61 607 all phecode
269 Proteinuria Endocrine/metabolic 0.986 0.926 – 1.05 0.648 1079 10768 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.02 0.948 – 1.1 0.558 740 7378 all phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.904 0.754 – 1.08 0.271 129 1283 all phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.885 0.722 – 1.08 0.238 101 998 all phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 1.06 0.845 – 1.34 0.601 81 810 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.04 0.957 – 1.14 0.333 560 5581 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.03 0.911 – 1.16 0.676 301 2982 all phecode
270.33 Amyloidosis Endocrine/metabolic 0.899 0.687 – 1.18 0.439 55 550 all phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.08 0.933 – 1.24 0.312 218 2178 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.962 0.918 – 1.01 0.101 1952 19491 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.965 0.92 – 1.01 0.146 1885 18823 all phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.996 0.789 – 1.26 0.974 81 810 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.958 0.936 – 0.98 0.000169 14793 22696 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.958 0.936 – 0.98 0.00017 14763 22682 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.966 0.934 – 0.999 0.0407 4668 18640 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.869 0.812 – 0.931 5.73e-05 945 9395 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.932 0.892 – 0.975 0.00216 2272 15492 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.964 0.846 – 1.1 0.575 244 2425 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.06 1.01 – 1.11 0.0169 1971 18337 all phecode
274.1 Gout Endocrine/metabolic 1.05 1 – 1.1 0.04 1879 17712 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.09 1.01 – 1.17 0.0261 793 7891 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.11 0.935 – 1.31 0.236 146 1425 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.13 0.946 – 1.34 0.182 140 1363 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.986 0.951 – 1.02 0.451 3252 30253 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.95 0.812 – 1.11 0.524 168 1680 all phecode
275.11 Hereditary hemochromatosis Hematopoietic 0.903 0.714 – 1.14 0.398 70 700 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 0.969 0.902 – 1.04 0.377 845 8441 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1 0.963 – 1.05 0.863 2502 24757 all phecode
275.51 Hypocalcemia Endocrine/metabolic 0.994 0.921 – 1.07 0.882 722 7203 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.977 0.917 – 1.04 0.481 1024 10193 all phecode
275.6 Hypercalcemia Endocrine/metabolic 0.991 0.93 – 1.06 0.774 1043 10415 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 0.987 0.962 – 1.01 0.325 7227 30901 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 0.981 0.951 – 1.01 0.22 4833 28673 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.983 0.888 – 1.09 0.743 415 4115 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 0.986 0.94 – 1.03 0.558 1857 17982 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 0.989 0.947 – 1.03 0.625 2238 20576 all phecode
276.14 Hypopotassemia Endocrine/metabolic 0.988 0.939 – 1.04 0.639 1626 16160 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.981 0.932 – 1.03 0.463 1593 15855 all phecode
276.41 Acidosis Endocrine/metabolic 0.954 0.902 – 1.01 0.0964 1357 13508 all phecode
276.42 Alkalosis Endocrine/metabolic 1.04 0.929 – 1.16 0.526 350 3498 all phecode
276.5 Hypovolemia Endocrine/metabolic 0.992 0.958 – 1.03 0.651 3615 28901 all phecode
276.6 Fluid overload Endocrine/metabolic 0.997 0.935 – 1.06 0.921 1046 10404 all phecode
276.8 Polydipsia Endocrine/metabolic 0.894 0.727 – 1.1 0.285 99 990 all phecode
277 Other disorders of metabolism Endocrine/metabolic 0.922 0.875 – 0.973 0.00293 1534 15324 all phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 0.965 0.849 – 1.1 0.585 252 2520 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.98 0.897 – 1.07 0.657 547 5456 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.927 0.855 – 1 0.0616 675 6743 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.92 0.843 – 1 0.0609 567 5665 all phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 0.934 0.859 – 1.01 0.107 610 6090 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.977 0.957 – 0.997 0.0273 15130 23191 all phecode
278.1 Obesity Endocrine/metabolic 0.973 0.952 – 0.994 0.0117 13507 23193 all phecode
278.11 Morbid obesity Endocrine/metabolic 0.969 0.942 – 0.996 0.0264 6376 23143 all phecode
278.3 Localized adiposity Endocrine/metabolic 0.832 0.734 – 0.944 0.00436 270 2694 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.975 0.924 – 1.03 0.356 1522 13685 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.984 0.942 – 1.03 0.484 2245 22393 all phecode
279.1 Immunity deficiency Endocrine/metabolic 0.979 0.913 – 1.05 0.542 881 8792 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.94 0.825 – 1.07 0.351 254 2540 all phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 0.924 0.848 – 1.01 0.0733 574 5735 all phecode
279.7 Other immunological findings Endocrine/metabolic 0.979 0.947 – 1.01 0.225 3927 30734 all phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 0.985 0.893 – 1.09 0.759 443 4423 all phecode
280 Iron deficiency anemias Hematopoietic 0.983 0.949 – 1.02 0.346 3537 25593 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.98 0.946 – 1.02 0.28 3410 25349 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.997 0.942 – 1.05 0.903 1361 13511 all phecode
281 Other deficiency anemia Hematopoietic 1.01 0.905 – 1.12 0.914 387 3838 all phecode
281.1 Megaloblastic anemia Hematopoietic 1.05 0.908 – 1.22 0.5 189 1875 all phecode
281.11 Pernicious anemia Hematopoietic 1.04 0.838 – 1.3 0.704 84 830 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.05 0.882 – 1.25 0.583 135 1348 all phecode
281.9 Deficiency anemias Hematopoietic 0.947 0.821 – 1.09 0.457 214 2110 all phecode
282 Hereditary hemolytic anemias Hematopoietic 0.866 0.759 – 0.988 0.0331 248 2443 all phecode
282.8 Other hemoglobinopathies Hematopoietic 0.868 0.733 – 1.03 0.0972 158 1541 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.86 0.722 – 1.02 0.0912 143 1420 all phecode
283 Acquired hemolytic anemias Hematopoietic 0.988 0.823 – 1.19 0.899 130 1295 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.05 0.795 – 1.4 0.711 54 532 all phecode
284 Aplastic anemia Hematopoietic 0.929 0.85 – 1.01 0.102 558 5545 all phecode
284.1 Pancytopenia Hematopoietic 0.94 0.855 – 1.03 0.204 488 4847 all phecode
285 Other anemias Hematopoietic 0.981 0.958 – 1 0.115 9426 28014 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.981 0.941 – 1.02 0.369 2536 22457 all phecode
285.2 Anemia of chronic disease Hematopoietic 0.992 0.942 – 1.05 0.771 1584 15823 all phecode
285.21 Anemia in chronic kidney disease Hematopoietic 0.969 0.895 – 1.05 0.428 673 6722 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.994 0.912 – 1.08 0.887 555 5536 all phecode
286 Coagulation defects Hematopoietic 0.99 0.954 – 1.03 0.621 3013 27144 all phecode
286.1 Congenital coagulation defects Hematopoietic 0.925 0.796 – 1.07 0.306 190 1889 all phecode
286.11 Von willebrand's disease Hematopoietic 0.898 0.693 – 1.16 0.415 64 640 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.84 0.684 – 1.03 0.0974 98 973 all phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 0.995 0.955 – 1.04 0.821 2601 20964 all phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 1.07 0.81 – 1.41 0.645 60 590 all phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 0.906 0.779 – 1.05 0.202 186 1860 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.15 0.928 – 1.43 0.197 92 906 all phecode
286.6 Defibrination syndrome Hematopoietic 0.974 0.929 – 1.02 0.263 1964 19522 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.985 0.944 – 1.03 0.478 2349 23153 all phecode
286.8 Hypercoagulable state Hematopoietic 0.969 0.892 – 1.05 0.447 643 6420 all phecode
286.81 Primary hypercoagulable state Hematopoietic 0.956 0.879 – 1.04 0.294 618 6179 all phecode
286.9 Abnormal coagulation profile Hematopoietic 1 0.937 – 1.08 0.893 890 8770 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.01 0.97 – 1.05 0.623 2575 22699 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.931 0.789 – 1.1 0.401 154 1532 all phecode
287.3 Thrombocytopenia Hematopoietic 1 0.959 – 1.05 0.947 2297 20909 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.03 0.937 – 1.13 0.542 481 4785 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.918 0.832 – 1.01 0.0918 436 4360 all phecode
287.4 Qualitative platelet defects Hematopoietic 0.942 0.743 – 1.2 0.625 76 760 all phecode
288 Diseases of white blood cells Hematopoietic 0.983 0.95 – 1.02 0.314 3850 30383 all phecode
288.1 Decreased white blood cell count Hematopoietic 1.01 0.957 – 1.08 0.633 1252 12520 all phecode
288.11 Neutropenia Hematopoietic 1.01 0.943 – 1.08 0.753 896 8960 all phecode
288.2 Elevated white blood cell count Hematopoietic 0.977 0.942 – 1.01 0.215 3179 28632 all phecode
288.3 Eosinophilia Hematopoietic 0.968 0.804 – 1.16 0.729 128 1278 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.972 0.917 – 1.03 0.346 1259 12554 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.97 0.893 – 1.05 0.473 615 6123 all phecode
289.4 Lymphadenitis Hematopoietic 1.01 0.978 – 1.05 0.442 3186 28420 all phecode
289.5 Diseases of spleen Hematopoietic 0.88 0.783 – 0.989 0.0314 313 3130 all phecode
289.8 Polycythemia, secondary Hematopoietic 0.939 0.806 – 1.09 0.417 182 1820 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.03 0.913 – 1.17 0.612 281 2776 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.923 0.866 – 0.984 0.0141 1040 9399 all phecode
290.1 Dementias Mental Disorders 0.866 0.782 – 0.958 0.00542 407 3816 all phecode
290.11 Alzheimer's disease Mental Disorders 0.863 0.706 – 1.06 0.152 104 984 all phecode
290.12 Dementia with cerebral degenerations Mental Disorders 0.82 0.645 – 1.04 0.104 71 705 all phecode
290.13 Senile dementia Mental Disorders 0.87 0.766 – 0.988 0.0315 257 2376 all phecode
290.16 Vascular dementia Mental Disorders 0.881 0.67 – 1.16 0.367 53 508 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.96 0.885 – 1.04 0.324 634 6242 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.954 0.879 – 1.03 0.254 642 6369 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.938 0.895 – 0.983 0.0073 1977 19673 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.994 0.846 – 1.17 0.946 161 1610 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.904 0.811 – 1.01 0.0677 364 3634 all phecode
291.8 Alteration of consciousness Mental Disorders 0.942 0.893 – 0.992 0.0243 1563 15497 all phecode
292 Neurological disorders Mental Disorders 0.963 0.933 – 0.995 0.0216 4340 31695 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.915 0.868 – 0.964 0.000921 1554 15459 all phecode
292.11 Aphasia Mental Disorders 0.882 0.806 – 0.966 0.00695 516 5142 all phecode
292.12 Symbolic dysfunction Mental Disorders 0.89 0.759 – 1.04 0.15 162 1620 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.871 0.77 – 0.987 0.0298 276 2716 all phecode
292.3 Memory loss Mental Disorders 0.982 0.929 – 1.04 0.518 1405 13752 all phecode
292.4 Altered mental status Mental Disorders 0.952 0.907 – 0.998 0.0427 1885 18096 all phecode
292.5 Transient alteration of awareness Mental Disorders 0.868 0.773 – 0.974 0.0157 327 3237 all phecode
292.6 Hallucinations Mental Disorders 1.03 0.866 – 1.21 0.773 144 1429 all phecode
293 Symptoms involving head and neck Mental Disorders 1.02 0.902 – 1.14 0.8 304 3036 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.988 0.955 – 1.02 0.508 3691 32427 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.981 0.905 – 1.06 0.647 664 6564 all phecode
295.1 Schizophrenia Mental Disorders 1.07 0.878 – 1.3 0.51 111 1080 all phecode
295.2 Paranoid disorders Mental Disorders 0.915 0.732 – 1.14 0.436 86 856 all phecode
295.3 Psychosis Mental Disorders 0.997 0.91 – 1.09 0.943 527 5206 all phecode
296 Mood disorders Mental Disorders 0.999 0.975 – 1.02 0.905 12028 17942 all phecode
296.1 Bipolar Mental Disorders 1.04 0.974 – 1.11 0.242 994 9331 all phecode
296.2 Depression Mental Disorders 0.996 0.973 – 1.02 0.771 11641 17941 all phecode
296.22 Major depressive disorder Mental Disorders 1 0.976 – 1.03 0.963 10773 17942 all phecode
297 Suicidal ideation or attempt Mental Disorders 1.01 0.933 – 1.09 0.812 696 6932 all phecode
297.1 Suicidal ideation Mental Disorders 1.04 0.949 – 1.13 0.433 559 5575 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.01 0.873 – 1.17 0.876 201 2010 all phecode
300 Anxiety disorders Mental Disorders 0.996 0.973 – 1.02 0.733 12038 17949 all phecode
300.1 Anxiety disorder Mental Disorders 0.999 0.975 – 1.02 0.945 11352 17942 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1 0.97 – 1.04 0.861 4496 17788 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.96 0.897 – 1.03 0.238 957 9152 all phecode
300.13 Phobia Mental Disorders 1.03 0.952 – 1.11 0.476 731 7231 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.975 0.849 – 1.12 0.726 223 2230 all phecode
300.4 Dysthymic disorder Mental Disorders 0.977 0.93 – 1.03 0.363 1798 13630 all phecode
300.8 Acute reaction to stress Mental Disorders 0.924 0.827 – 1.03 0.158 359 3536 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.964 0.886 – 1.05 0.383 612 6113 all phecode
301 Personality disorders Mental Disorders 1.02 0.91 – 1.14 0.769 363 3626 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.04 0.897 – 1.21 0.582 187 1868 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.949 0.873 – 1.03 0.223 608 6055 all phecode
302.1 Decreased libido Mental Disorders 0.91 0.812 – 1.02 0.105 325 3233 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.991 0.929 – 1.06 0.794 1030 10064 all phecode
303.1 Dissociative disorder Mental Disorders 1.1 0.913 – 1.34 0.306 115 1144 all phecode
303.3 Psychogenic disorder Mental Disorders 0.982 0.91 – 1.06 0.634 736 7330 all phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 1.02 0.912 – 1.14 0.73 340 3376 all phecode
303.4 Somatoform disorder Mental Disorders 1.03 0.959 – 1.1 0.439 925 9106 all phecode
304 Adjustment reaction Mental Disorders 0.974 0.936 – 1.01 0.199 2840 17464 all phecode
305.2 Eating disorder Mental Disorders 0.98 0.904 – 1.06 0.635 650 6500 all phecode
306 Other mental disorder Mental Disorders 0.992 0.935 – 1.05 0.778 1254 10907 all phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 0.922 0.831 – 1.02 0.126 418 2847 all phecode
306.9 Tension headache Mental Disorders 0.972 0.887 – 1.06 0.543 521 5210 all phecode
312 Conduct disorders Mental Disorders 0.846 0.73 – 0.981 0.027 189 1890 all phecode
312.3 Impulse control disorder Mental Disorders 0.909 0.682 – 1.21 0.516 53 530 all phecode
313 Pervasive developmental disorders Mental Disorders 0.995 0.936 – 1.06 0.882 1148 11078 all phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1 0.938 – 1.07 0.967 1012 9899 all phecode
313.2 Tics and stuttering Mental Disorders 0.912 0.702 – 1.19 0.492 60 593 all phecode
315 Develomental delays and disorders Mental Disorders 0.953 0.86 – 1.06 0.355 401 3990 all phecode
315.1 Learning disorder Mental Disorders 1.01 0.779 – 1.31 0.929 60 599 all phecode
315.2 Speech and language disorder Mental Disorders 0.896 0.771 – 1.04 0.152 182 1801 all phecode
316 Substance addiction and disorders Mental Disorders 0.997 0.958 – 1.04 0.865 2799 26014 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.993 0.908 – 1.09 0.881 518 5180 all phecode
317 Alcohol-related disorders Mental Disorders 0.957 0.913 – 1 0.0701 1948 17547 all phecode
317.1 Alcoholism Mental Disorders 0.955 0.905 – 1.01 0.0894 1517 14733 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.04 0.931 – 1.16 0.48 335 3336 all phecode
318 Tobacco use disorder Mental Disorders 1.01 0.985 – 1.03 0.458 9473 26924 all phecode
320 Meningitis Neurological 0.979 0.87 – 1.1 0.723 319 3181 all phecode
323 Encephalitis Neurological 0.868 0.728 – 1.03 0.113 148 1475 all phecode
323.8 Encephalitis, non-infectious Neurological 0.82 0.673 – 0.998 0.0482 125 1245 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.06 0.931 – 1.21 0.379 245 2440 all phecode
327 Sleep disorders Neurological 0.975 0.954 – 0.997 0.0259 11517 26652 all phecode
327.1 Hypersomnia Neurological 0.969 0.917 – 1.02 0.262 1403 13919 all phecode
327.3 Sleep apnea Neurological 0.972 0.947 – 0.996 0.0242 8293 26193 all phecode
327.31 Central/nonobstroctive sleep apnea Neurological 0.969 0.864 – 1.09 0.588 326 3234 all phecode
327.32 Obstructive sleep apnea Neurological 0.968 0.941 – 0.995 0.0192 6534 25537 all phecode
327.4 Insomnia Neurological 0.971 0.94 – 1 0.0825 4197 25860 all phecode
327.41 Organic or persistent insomnia Neurological 0.92 0.859 – 0.986 0.0186 881 8743 all phecode
327.5 Parasomnia Neurological 0.924 0.839 – 1.02 0.108 459 4583 all phecode
327.6 Circadian rhythm sleep disorder Neurological 1.01 0.865 – 1.18 0.911 174 1738 all phecode
327.7 Sleep related movement disorders Neurological 0.969 0.917 – 1.02 0.264 1364 13620 all phecode
327.71 Restless legs syndrome Neurological 0.974 0.919 – 1.03 0.386 1214 12132 all phecode
327.72 Sleep related leg cramps Neurological 1.12 0.855 – 1.46 0.419 55 550 all phecode
331 Other cerebral degenerations Neurological 0.928 0.853 – 1.01 0.0811 602 5935 all phecode
331.1 Hydrocephalus Neurological 0.995 0.874 – 1.13 0.941 246 2447 all phecode
331.9 Cerebral degeneration, unspecified Neurological 0.894 0.801 – 0.999 0.0476 349 3423 all phecode
332 Parkinson's disease Neurological 0.952 0.85 – 1.07 0.397 333 3321 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1 0.958 – 1.05 0.946 2169 20920 all phecode
333.1 Essential tremor Neurological 1.04 0.953 – 1.13 0.377 551 5488 all phecode
333.2 Myoclonus Neurological 0.983 0.818 – 1.18 0.853 117 1160 all phecode
333.4 Torsion dystonia Neurological 1.11 0.984 – 1.26 0.0875 266 2646 all phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 1.08 0.849 – 1.37 0.541 64 640 all phecode
334 Degenerative disease of the spinal cord Neurological 0.985 0.918 – 1.06 0.667 874 8734 all phecode
334.1 Spinocerebellar disease Neurological 1 0.771 – 1.3 0.999 64 631 all phecode
334.2 Anterior horn cell disease Neurological 0.861 0.699 – 1.06 0.162 92 920 all phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 0.853 0.655 – 1.11 0.237 57 570 all phecode
335 Multiple sclerosis Neurological 0.97 0.867 – 1.09 0.598 330 3284 all phecode
337 Disorders of the autonomic nervous system Neurological 1.01 0.924 – 1.11 0.813 528 5257 all phecode
337.1 Peripheral autonomic neuropathy Neurological 0.949 0.815 – 1.1 0.497 185 1837 all phecode
338 Pain Neurological 0.99 0.97 – 1.01 0.311 16189 22165 all phecode
338.1 Acute pain Neurological 0.991 0.969 – 1.01 0.398 12567 22166 all phecode
338.2 Chronic pain Neurological 0.979 0.954 – 1 0.104 8223 22154 all phecode
339 Other headache syndromes Neurological 0.992 0.968 – 1.02 0.53 8578 27793 all phecode
340 Migraine Neurological 0.988 0.958 – 1.02 0.432 5377 24263 all phecode
340.1 Migrain with aura Neurological 0.993 0.954 – 1.03 0.747 2862 18665 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.975 0.802 – 1.19 0.8 111 1105 all phecode
342 Hemiplegia Neurological 0.892 0.801 – 0.993 0.037 360 3589 all phecode
343 Infantile cerebral palsy Neurological 0.921 0.73 – 1.16 0.488 75 750 all phecode
344 Other paralytic syndromes Neurological 0.973 0.892 – 1.06 0.527 564 5640 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.964 0.922 – 1.01 0.115 2084 20790 all phecode
345.1 Epilepsy Neurological 0.947 0.87 – 1.03 0.2 607 6053 all phecode
345.11 Generalized convulsive epilepsy Neurological 0.932 0.805 – 1.08 0.348 196 1960 all phecode
345.12 Partial epilepsy Neurological 0.962 0.87 – 1.06 0.441 434 4333 all phecode
345.3 Convulsions Neurological 0.961 0.917 – 1.01 0.0913 1967 19598 all phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 1.05 0.877 – 1.25 0.619 142 1404 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.01 0.953 – 1.07 0.712 1196 11927 all phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 1.01 0.806 – 1.26 0.941 87 860 all phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 0.858 0.69 – 1.07 0.166 90 884 all phecode
347 Cataplexy and narcolepsy Neurological 1.01 0.794 – 1.28 0.945 67 670 all phecode
348 Other conditions of brain Neurological 0.938 0.888 – 0.991 0.0214 1424 14226 all phecode
348.2 Cerebral edema and compression of brain Neurological 0.947 0.878 – 1.02 0.16 747 7463 all phecode
348.4 Cerebral cysts Neurological 0.921 0.795 – 1.07 0.279 195 1945 all phecode
348.7 Coma Neurological 0.882 0.746 – 1.04 0.141 162 1620 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 0.895 0.825 – 0.972 0.00842 636 6331 all phecode
348.9 Other conditions of brain, NOS Neurological 0.992 0.947 – 1.04 0.721 2001 19979 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.954 0.886 – 1.03 0.212 775 7750 all phecode
350 Abnormal movement Neurological 0.993 0.964 – 1.02 0.633 5109 32314 all phecode
350.1 Abnormal involuntary movements Neurological 0.986 0.946 – 1.03 0.518 2464 24243 all phecode
350.2 Abnormality of gait Neurological 0.982 0.945 – 1.02 0.343 2979 25007 all phecode
350.3 Lack of coordination Neurological 0.956 0.887 – 1.03 0.239 773 7693 all phecode
350.5 Abnormal reflex Neurological 0.955 0.805 – 1.13 0.6 143 1430 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.93 0.844 – 1.03 0.145 448 4480 all phecode
351 Other peripheral nerve disorders Neurological 0.962 0.934 – 0.99 0.00761 5685 28844 all phecode
352 Disorders of other cranial nerves Neurological 1.02 0.963 – 1.08 0.539 1412 14120 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.938 0.849 – 1.04 0.205 440 4393 all phecode
352.2 Facial nerve disorders [CN7] Neurological 0.958 0.883 – 1.04 0.304 640 6400 all phecode
353 Nerve root and plexus disorders Neurological 0.97 0.936 – 1.01 0.104 3295 28097 all phecode
353.1 Nerve plexus lesions Neurological 0.886 0.789 – 0.994 0.04 308 3077 all phecode
353.2 Nerve root lesions Neurological 0.994 0.805 – 1.23 0.956 94 930 all phecode
355 Complex regional/central pain syndrome Neurological 1.09 0.984 – 1.2 0.0998 419 4170 all phecode
355.1 Chronic pain syndrome Neurological 1.01 0.932 – 1.09 0.822 654 6509 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.947 0.901 – 0.995 0.0311 1728 17176 all phecode
357 Inflammatory and toxic neuropathy Neurological 0.945 0.906 – 0.985 0.00768 2467 24091 all phecode
358 Myoneural disorders Neurological 0.947 0.882 – 1.02 0.129 845 8441 all phecode
358.1 Myasthenia gravis Neurological 1.03 0.812 – 1.29 0.834 85 850 all phecode
359 Muscular dystrophies and other myopathies Neurological 1.01 0.94 – 1.08 0.828 868 8655 all phecode
359.1 Muscular dystrophies Neurological 0.896 0.687 – 1.17 0.419 52 520 all phecode
359.2 Myopathy Neurological 1.02 0.951 – 1.1 0.568 833 8306 all phecode
360 Disorders of the globe Sense Organs 0.957 0.78 – 1.17 0.672 102 1013 all phecode
361 Retinal detachments and defects Sense Organs 0.979 0.895 – 1.07 0.649 528 5265 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.98 0.857 – 1.12 0.771 225 2226 all phecode
362 Other retinal disorders Sense Organs 0.994 0.953 – 1.04 0.78 2489 18838 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.995 0.943 – 1.05 0.851 1529 12328 all phecode
362.21 Macular degeneration, dry Sense Organs 1.03 0.916 – 1.16 0.627 313 2650 all phecode
362.22 Macular degeneration, wet Sense Organs 1.15 0.937 – 1.41 0.181 108 881 all phecode
362.23 Cystoid macular degeneration of retina Sense Organs 0.903 0.797 – 1.02 0.105 285 2777 all phecode
362.26 Macular puckering of retina Sense Organs 0.99 0.912 – 1.07 0.802 645 6254 all phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.981 0.877 – 1.1 0.733 335 3205 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.992 0.937 – 1.05 0.786 1323 10928 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.954 0.88 – 1.03 0.255 653 6476 all phecode
362.31 Separation of retinal layers Sense Organs 0.972 0.862 – 1.09 0.636 296 2938 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.998 0.907 – 1.1 0.969 449 4295 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.965 0.851 – 1.09 0.578 262 2600 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.05 0.877 – 1.25 0.605 124 1233 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.914 0.777 – 1.07 0.272 160 1570 all phecode
362.9 Retinal edema Sense Organs 1 0.869 – 1.16 0.966 202 2001 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1 0.903 – 1.11 0.954 375 3665 all phecode
363.3 Chorioretinal scars Sense Organs 1.04 0.914 – 1.19 0.545 249 2430 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.985 0.916 – 1.06 0.677 809 7919 all phecode
364.1 Corneal opacity Sense Organs 1.01 0.897 – 1.14 0.855 294 2930 all phecode
364.2 Corneal edema Sense Organs 0.973 0.78 – 1.21 0.811 84 819 all phecode
364.4 Corneal degenerations Sense Organs 0.956 0.847 – 1.08 0.473 274 2719 all phecode
364.5 Corneal dystrophy Sense Organs 1.02 0.921 – 1.14 0.673 377 3673 all phecode
364.51 Fuchs' dystrophy Sense Organs 1.06 0.918 – 1.21 0.449 207 2008 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.901 0.706 – 1.15 0.4 69 677 all phecode
365 Glaucoma Sense Organs 0.995 0.95 – 1.04 0.833 1986 17152 all phecode
365.1 Open-angle glaucoma Sense Organs 0.966 0.883 – 1.06 0.456 523 4963 all phecode
365.11 Primary open angle glaucoma Sense Organs 0.908 0.803 – 1.03 0.127 281 2609 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.13 0.966 – 1.31 0.13 179 1707 all phecode
366 Cataract Sense Organs 0.977 0.949 – 1.01 0.126 6335 23476 all phecode
366.1 Nonsenile Cataract Sense Organs 0.866 0.739 – 1.01 0.0745 163 1622 all phecode
366.2 Senile cataract Sense Organs 0.971 0.937 – 1.01 0.107 3827 20410 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.949 0.924 – 0.975 0.000152 6553 31745 all phecode
367.1 Myopia Sense Organs 0.94 0.907 – 0.973 0.000529 3578 28818 all phecode
367.2 Astigmatism Sense Organs 0.96 0.924 – 0.998 0.0413 2892 26106 all phecode
367.4 Presbyopia Sense Organs 0.956 0.922 – 0.992 0.0166 3297 24582 all phecode
367.8 Hypermetropia Sense Organs 0.943 0.894 – 0.994 0.0302 1504 14729 all phecode
367.9 Blindness and low vision Sense Organs 0.966 0.905 – 1.03 0.303 976 9663 all phecode
368 Visual disturbances Sense Organs 0.982 0.951 – 1.01 0.272 4287 32818 all phecode
368.1 Amblyopia Sense Organs 0.967 0.88 – 1.06 0.485 484 4830 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.02 0.949 – 1.09 0.597 822 8186 all phecode
368.3 Anisometropia Sense Organs 0.933 0.796 – 1.09 0.389 166 1648 all phecode
368.4 Visual field defects Sense Organs 0.987 0.921 – 1.06 0.717 879 8777 all phecode
368.9 Subjective visual disturbances Sense Organs 0.982 0.914 – 1.05 0.622 829 8268 all phecode
368.91 Psychophysical visual disturbances Sense Organs 0.913 0.736 – 1.13 0.406 89 885 all phecode
369 Infection of the eye Sense Organs 0.973 0.932 – 1.02 0.216 2328 22262 all phecode
369.2 Eye infection, viral Sense Organs 0.989 0.889 – 1.1 0.843 372 3688 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.964 0.92 – 1.01 0.127 1974 19408 all phecode
370 Keratitis Sense Organs 0.975 0.915 – 1.04 0.435 1051 10280 all phecode
370.1 Corneal ulcer Sense Organs 0.981 0.839 – 1.15 0.807 164 1630 all phecode
370.2 Superficial keratitis Sense Organs 0.947 0.852 – 1.05 0.312 394 3916 all phecode
370.3 Keratoconjunctivitis Sense Organs 0.972 0.889 – 1.06 0.529 531 5159 all phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.898 0.758 – 1.06 0.215 150 1432 all phecode
371 Inflammation of the eye Sense Organs 0.994 0.959 – 1.03 0.764 3269 26161 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.881 0.793 – 0.978 0.0178 394 3892 all phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.974 0.899 – 1.06 0.531 651 6462 all phecode
371.21 Allergic conjunctivitis Sense Organs 0.955 0.873 – 1.05 0.322 532 5279 all phecode
371.3 Inflammation of eyelids Sense Organs 1.01 0.972 – 1.06 0.544 2523 21781 all phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 0.985 0.802 – 1.21 0.886 100 979 all phecode
372 Disorders of conjunctiva Sense Organs 1.05 0.975 – 1.12 0.211 827 8153 all phecode
374 Other disorders of eyelids Sense Organs 0.985 0.941 – 1.03 0.513 2093 18512 all phecode
374.1 Ectropion or entropion Sense Organs 1.15 1.03 – 1.29 0.0116 337 3251 all phecode
374.2 Lagophthalmos Sense Organs 1.11 0.957 – 1.28 0.172 192 1900 all phecode
374.3 Ptosis of eyelid Sense Organs 0.961 0.893 – 1.03 0.28 817 8140 all phecode
374.6 Dermatochalasis Sense Organs 0.974 0.904 – 1.05 0.494 759 7426 all phecode
375 Disorders of lacrimal system Sense Organs 0.97 0.931 – 1.01 0.14 2683 21054 all phecode
375.1 Dry eyes Sense Organs 0.951 0.914 – 0.989 0.0113 2966 21823 all phecode
375.2 Epiphora Sense Organs 1.06 0.949 – 1.18 0.308 356 3540 all phecode
376 Disorders of the orbit Sense Organs 0.892 0.79 – 1.01 0.0641 285 2814 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.932 0.862 – 1.01 0.0798 706 7010 all phecode
377.1 Optic atrophy Sense Organs 1 0.867 – 1.16 0.979 200 1997 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.896 0.813 – 0.987 0.0254 468 4627 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.954 0.893 – 1.02 0.17 969 9602 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.91 0.838 – 0.988 0.0245 617 6131 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.12 0.938 – 1.35 0.206 138 1371 all phecode
378.5 Paralytic strabismus Sense Organs 1.06 0.938 – 1.21 0.337 275 2720 all phecode
379 Other disorders of eye Sense Organs 0.991 0.957 – 1.03 0.629 3593 24835 all phecode
379.1 Scleritis and episcleritis Sense Organs 1.17 0.992 – 1.39 0.0627 140 1379 all phecode
379.2 Disorders of vitreous body Sense Organs 0.979 0.939 – 1.02 0.317 2559 18709 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.911 0.735 – 1.13 0.394 87 838 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.04 0.906 – 1.19 0.572 231 2303 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.985 0.854 – 1.14 0.83 215 2128 all phecode
379.51 Pigmentary iris degeneration Sense Organs 0.927 0.711 – 1.21 0.571 61 610 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.973 0.907 – 1.04 0.453 870 8594 all phecode
380 Disorders of external ear Sense Organs 0.983 0.934 – 1.03 0.514 1634 15553 all phecode
380.1 Otitis externa Sense Organs 0.908 0.853 – 0.965 0.00204 1124 11213 all phecode
380.4 Impacted cerumen Sense Organs 0.959 0.915 – 1 0.0796 1985 18630 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.984 0.949 – 1.02 0.38 3291 29339 all phecode
381.1 Otitis media Sense Organs 0.98 0.94 – 1.02 0.352 2402 23549 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.976 0.932 – 1.02 0.3 2037 20175 all phecode
381.2 Eustachian tube disorders Sense Organs 0.978 0.925 – 1.03 0.442 1393 13815 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.01 0.84 – 1.21 0.923 126 1260 all phecode
381.9 Otorrhea Sense Organs 1.1 0.979 – 1.24 0.108 297 2960 all phecode
382 Otalgia Sense Organs 1 0.949 – 1.06 0.927 1425 14188 all phecode
383 Otosclerosis Sense Organs 0.983 0.811 – 1.19 0.866 112 1120 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.02 0.918 – 1.13 0.731 397 3962 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.01 0.903 – 1.14 0.82 318 3180 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1 0.901 – 1.12 0.936 358 3580 all phecode
385.3 Cholesteatoma Sense Organs 1.03 0.899 – 1.17 0.705 245 2450 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.861 0.7 – 1.06 0.158 103 1025 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.994 0.942 – 1.05 0.824 1441 14255 all phecode
386.1 Meniere's disease Sense Organs 1.08 0.949 – 1.23 0.241 248 2464 all phecode
386.2 Peripheral or central vertigo Sense Organs 0.997 0.94 – 1.06 0.92 1209 11971 all phecode
386.21 Central origin vertigo Sense Organs 1.01 0.944 – 1.08 0.745 883 8759 all phecode
386.3 Labyrinthitis Sense Organs 1.02 0.958 – 1.08 0.553 1099 10904 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.993 0.964 – 1.02 0.623 5315 31605 all phecode
388 Other disorders of ear Sense Organs 1.02 0.949 – 1.11 0.534 699 6960 all phecode
389 Hearing loss Sense Organs 0.992 0.965 – 1.02 0.578 6285 31750 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.985 0.949 – 1.02 0.44 3130 24231 all phecode
389.2 Conductive hearing loss Sense Organs 0.973 0.9 – 1.05 0.498 717 7169 all phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.981 0.827 – 1.16 0.825 143 1338 all phecode
389.4 Tinnitus Sense Organs 0.997 0.948 – 1.05 0.918 1677 16701 all phecode
389.5 Disorders of acoustic nerve Sense Organs 1.2 0.98 – 1.46 0.0775 101 1010 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.01 0.949 – 1.07 0.823 1177 11253 all phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 0.927 0.822 – 1.04 0.211 284 2766 all phecode
394.2 Mitral valve disease Circulatory System 0.995 0.897 – 1.1 0.919 378 3735 all phecode
394.3 Aortic valve disease Circulatory System 0.909 0.767 – 1.08 0.267 150 1465 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.01 0.923 – 1.12 0.759 468 4624 all phecode
395 Heart valve disorders Circulatory System 1 0.968 – 1.04 0.797 3169 23926 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.01 0.957 – 1.06 0.828 1754 16787 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.977 0.928 – 1.03 0.382 1619 13932 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.08 0.975 – 1.2 0.136 373 3704 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.08 0.863 – 1.35 0.498 84 831 all phecode
395.6 Heart valve replaced Circulatory System 1 0.936 – 1.08 0.927 878 8213 all phecode
396 Abnormal heart sounds Circulatory System 0.981 0.948 – 1.01 0.265 3754 28453 all phecode
401 Hypertension Circulatory System 0.984 0.962 – 1.01 0.159 18784 19071 all phecode
401.1 Essential hypertension Circulatory System 0.983 0.961 – 1.01 0.139 18655 19070 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 0.985 0.941 – 1.03 0.501 2599 12045 all phecode
401.21 Hypertensive heart disease Circulatory System 0.992 0.907 – 1.08 0.853 556 4628 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.996 0.948 – 1.05 0.877 2015 10909 all phecode
401.3 Other hypertensive complications Circulatory System 0.998 0.952 – 1.05 0.945 2027 12961 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 0.958 0.915 – 1 0.0706 2132 15248 all phecode
411 Ischemic Heart Disease Circulatory System 0.977 0.95 – 1 0.0966 6970 25468 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.01 0.934 – 1.09 0.815 702 6842 all phecode
411.2 Myocardial infarction Circulatory System 0.992 0.953 – 1.03 0.688 2849 17983 all phecode
411.3 Angina pectoris Circulatory System 0.984 0.938 – 1.03 0.501 1904 15218 all phecode
411.4 Coronary atherosclerosis Circulatory System 0.974 0.945 – 1 0.0806 5938 22890 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.01 0.835 – 1.22 0.929 117 1149 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.974 0.943 – 1.01 0.113 4877 21174 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.989 0.883 – 1.11 0.855 335 3247 all phecode
414 Other forms of chronic heart disease Circulatory System 1 0.961 – 1.05 0.889 2360 18485 all phecode
414.2 ASCVD Circulatory System 0.989 0.902 – 1.08 0.817 492 4846 all phecode
415 Pulmonary heart disease Circulatory System 0.981 0.943 – 1.02 0.345 2726 25061 all phecode
415.1 Acute pulmonary heart disease Circulatory System 0.981 0.93 – 1.03 0.482 1510 15045 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.984 0.933 – 1.04 0.55 1507 15014 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.978 0.927 – 1.03 0.4 1506 14839 all phecode
415.21 Primary pulmonary hypertension Circulatory System 0.967 0.889 – 1.05 0.429 592 5901 all phecode
416 Cardiomegaly Circulatory System 0.951 0.889 – 1.02 0.145 935 9293 all phecode
418 Nonspecific chest pain Circulatory System 0.983 0.96 – 1.01 0.137 10015 28233 all phecode
418.1 Precordial pain Circulatory System 1.02 0.959 – 1.08 0.564 1193 11816 all phecode
420 Carditis Circulatory System 0.98 0.925 – 1.04 0.487 1275 12633 all phecode
420.1 Myocarditis Circulatory System 0.928 0.737 – 1.17 0.525 76 752 all phecode
420.2 Pericarditis Circulatory System 0.991 0.916 – 1.07 0.823 684 6830 all phecode
420.21 Acute pericarditis Circulatory System 0.971 0.815 – 1.16 0.739 144 1435 all phecode
420.22 Chronic pericarditis Circulatory System 1.01 0.815 – 1.26 0.909 92 912 all phecode
420.3 Endocarditis Circulatory System 0.997 0.917 – 1.08 0.937 602 5990 all phecode
425 Cardiomyopathy Circulatory System 0.994 0.945 – 1.05 0.829 1617 15758 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.992 0.942 – 1.05 0.763 1557 15170 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.06 0.909 – 1.24 0.443 171 1699 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.1 0.937 – 1.3 0.24 154 1540 all phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.04 0.915 – 1.19 0.536 248 2480 all phecode
425.8 Other cardiomyopathy Circulatory System 1.05 0.836 – 1.33 0.654 71 709 all phecode
426 Cardiac conduction disorders Circulatory System 0.989 0.965 – 1.01 0.414 9881 21221 all phecode
426.2 Atrioventricular [AV] block Circulatory System 0.962 0.91 – 1.02 0.175 1527 9610 all phecode
426.21 First degree AV block Circulatory System 0.935 0.876 – 0.999 0.0476 1064 7510 all phecode
426.22 Mobitz II AV block Circulatory System 1.11 0.837 – 1.47 0.472 56 513 all phecode
426.23 Second degree AV block Circulatory System 1.05 0.89 – 1.25 0.543 161 1459 all phecode
426.24 Atrioventricular block, complete Circulatory System 1 0.898 – 1.12 0.962 357 3041 all phecode
426.25 Other heart block Circulatory System 1.07 0.912 – 1.27 0.389 161 1489 all phecode
426.3 Bundle branch block Circulatory System 1.01 0.957 – 1.06 0.794 1775 11373 all phecode
426.31 Right bundle branch block Circulatory System 1.01 0.95 – 1.08 0.705 1101 8763 all phecode
426.32 Left bundle branch block Circulatory System 0.996 0.922 – 1.08 0.925 721 6217 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.879 0.68 – 1.14 0.326 62 611 all phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 0.99 0.964 – 1.02 0.465 8452 21094 all phecode
426.8 Other cardiac conduction disorders Circulatory System 0.975 0.885 – 1.07 0.611 456 4529 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.988 0.93 – 1.05 0.699 1261 8802 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.988 0.918 – 1.06 0.758 836 6124 all phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.01 0.928 – 1.1 0.839 628 5698 all phecode
427 Cardiac dysrhythmias Circulatory System 0.989 0.967 – 1.01 0.311 14018 21321 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 0.972 0.926 – 1.02 0.247 1882 14769 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.979 0.922 – 1.04 0.492 1193 11216 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.94 0.876 – 1.01 0.0894 892 7975 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 0.983 0.948 – 1.02 0.352 4194 15493 all phecode
427.21 Atrial fibrillation Circulatory System 0.984 0.948 – 1.02 0.393 4097 15312 all phecode
427.22 Atrial flutter Circulatory System 0.991 0.938 – 1.05 0.739 1598 9674 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.985 0.958 – 1.01 0.281 7129 21276 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.885 0.799 – 0.981 0.0195 419 4137 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.795 0.677 – 0.935 0.0055 167 1670 all phecode
427.42 Cardiac arrest Circulatory System 0.934 0.831 – 1.05 0.25 321 3186 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.996 0.966 – 1.03 0.783 5521 21271 all phecode
427.6 Premature beats Circulatory System 0.974 0.926 – 1.02 0.303 1820 13218 all phecode
427.61 Supraventricular premature beats Circulatory System 0.931 0.849 – 1.02 0.124 522 4879 all phecode
427.7 Tachycardia NOS Circulatory System 1 0.968 – 1.04 0.913 3980 21286 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.957 0.886 – 1.03 0.265 738 6224 all phecode
427.9 Palpitations Circulatory System 0.992 0.956 – 1.03 0.656 3420 20157 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.964 0.928 – 1 0.0574 3326 19946 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 0.964 0.926 – 1 0.0671 2965 19130 all phecode
428.2 Heart failure NOS Circulatory System 0.979 0.94 – 1.02 0.304 2781 17962 all phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 0.984 0.929 – 1.04 0.593 1288 11396 all phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 0.97 0.913 – 1.03 0.315 1208 10616 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 0.981 0.957 – 1 0.114 9394 27581 all phecode
429.1 Heart transplant/surgery Circulatory System 1.01 0.942 – 1.09 0.757 823 8070 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.968 0.936 – 1 0.0484 4445 23965 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 0.984 0.958 – 1.01 0.226 7147 27443 all phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 0.971 0.891 – 1.06 0.492 591 5816 all phecode
430 Intracranial hemorrhage Circulatory System 0.968 0.891 – 1.05 0.431 633 6305 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.964 0.845 – 1.1 0.59 230 2300 all phecode
430.2 Intracerebral hemorrhage Circulatory System 0.914 0.814 – 1.03 0.13 314 3132 all phecode
430.3 Subdural hemorrhage Circulatory System 0.978 0.845 – 1.13 0.766 202 2017 all phecode
433 Cerebrovascular disease Circulatory System 0.998 0.966 – 1.03 0.887 4361 26660 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1 0.948 – 1.05 0.99 1533 12978 all phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.01 0.876 – 1.17 0.849 188 1858 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.02 0.796 – 1.31 0.878 61 599 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.982 0.937 – 1.03 0.454 1926 17593 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.986 0.94 – 1.03 0.57 1862 17011 all phecode
433.3 Cerebral ischemia Circulatory System 1.01 0.961 – 1.05 0.819 2122 18040 all phecode
433.31 Transient cerebral ischemia Circulatory System 1 0.953 – 1.05 0.992 1812 16062 all phecode
433.5 Cerebral aneurysm Circulatory System 0.98 0.887 – 1.08 0.693 408 4070 all phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.06 0.953 – 1.18 0.287 383 3803 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.983 0.899 – 1.07 0.702 534 5286 all phecode
440 Atherosclerosis Circulatory System 0.978 0.933 – 1.03 0.36 1946 16499 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.03 0.889 – 1.19 0.689 187 1855 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.963 0.906 – 1.02 0.22 1166 11265 all phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 0.96 0.825 – 1.12 0.593 183 1815 all phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 0.97 0.902 – 1.04 0.408 812 7979 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.01 0.938 – 1.09 0.742 702 6800 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.03 0.929 – 1.14 0.58 407 4039 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.01 0.876 – 1.16 0.897 206 2025 all phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1 0.836 – 1.2 0.982 122 1207 all phecode
442 Other aneurysm Circulatory System 1 0.958 – 1.04 0.99 2309 18098 all phecode
442.1 Aortic aneurysm Circulatory System 0.987 0.938 – 1.04 0.613 1703 13812 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.03 0.963 – 1.1 0.417 992 9021 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.1 0.946 – 1.28 0.215 177 1769 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.986 0.83 – 1.17 0.874 137 1357 all phecode
442.4 Arterial dissection Circulatory System 1.05 0.887 – 1.24 0.58 156 1555 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.07 0.955 – 1.19 0.252 330 3300 all phecode
443 Peripheral vascular disease Circulatory System 1.01 0.968 – 1.05 0.653 2355 20353 all phecode
443.1 Raynaud's syndrome Circulatory System 1.02 0.939 – 1.11 0.649 608 6051 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.04 0.878 – 1.24 0.632 141 1375 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.01 0.965 – 1.06 0.631 1899 17476 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1 0.956 – 1.06 0.87 1747 15154 all phecode
444 Arterial embolism and thrombosis Circulatory System 0.988 0.913 – 1.07 0.755 675 6732 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.988 0.867 – 1.13 0.862 240 2392 all phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 0.948 0.792 – 1.13 0.555 129 1282 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.01 0.91 – 1.13 0.812 367 3641 all phecode
446.4 Wegener's granulomatosis Circulatory System 0.839 0.677 – 1.04 0.109 86 857 all phecode
446.5 Giant cell arteritis Circulatory System 1.09 0.829 – 1.43 0.536 59 547 all phecode
446.9 Arteritis NOS Circulatory System 1.05 0.917 – 1.2 0.474 230 2285 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1 0.958 – 1.05 0.917 2116 18819 all phecode
447.1 Stricture of artery Circulatory System 1.04 0.945 – 1.15 0.401 435 4322 all phecode
447.7 Aortic ectasia Circulatory System 0.965 0.889 – 1.05 0.387 637 6315 all phecode
448 Disease of capillaries Circulatory System 1.07 0.993 – 1.14 0.0762 853 8472 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.996 0.948 – 1.05 0.875 1701 17006 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.991 0.91 – 1.08 0.834 582 5764 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.05 0.9 – 1.22 0.553 190 1888 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.96 0.927 – 0.994 0.0204 3773 25068 all phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 0.984 0.861 – 1.13 0.817 228 2277 all phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 0.967 0.929 – 1.01 0.109 2623 22444 all phecode
452.8 Postphlebitic syndrome Circulatory System 1.01 0.837 – 1.22 0.908 119 1181 all phecode
453 Chronic venous hypertension Circulatory System 1.01 0.861 – 1.18 0.925 173 1715 all phecode
454 Varicose veins Circulatory System 0.96 0.918 – 1 0.0694 2206 20243 all phecode
454.1 Varicose veins of lower extremity Circulatory System 0.951 0.907 – 0.997 0.0375 1908 17574 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.959 0.903 – 1.02 0.169 1182 11754 all phecode
455 Hemorrhoids Circulatory System 0.974 0.943 – 1.01 0.114 4379 24588 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.942 0.902 – 0.984 0.00715 2303 20367 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.975 0.93 – 1.02 0.3 1946 14131 all phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 0.957 0.848 – 1.08 0.48 287 2845 all phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 0.977 0.93 – 1.03 0.352 1841 13661 all phecode
458 Hypotension Circulatory System 0.982 0.95 – 1.02 0.289 4073 28546 all phecode
458.1 Orthostatic hypotension Circulatory System 1.01 0.949 – 1.08 0.723 1031 10176 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.01 0.939 – 1.08 0.862 911 9084 all phecode
458.9 Hypotension NOS Circulatory System 0.976 0.943 – 1.01 0.172 3641 27465 all phecode
459 Other disorders of circulatory system Circulatory System 0.982 0.948 – 1.02 0.307 3553 27674 all phecode
459.1 Hemorrhage NOS Circulatory System 1 0.921 – 1.09 0.99 619 6159 all phecode
459.7 Blood vessel replaced Circulatory System 1.04 0.902 – 1.2 0.591 203 2030 all phecode
459.9 Circulatory disease NEC Circulatory System 0.978 0.94 – 1.02 0.266 2757 23656 all phecode
464 Acute sinusitis Respiratory 0.949 0.917 – 0.983 0.00334 3675 26562 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.956 0.931 – 0.981 0.000739 7223 30143 all phecode
465.2 Acute pharyngitis Respiratory 0.962 0.93 – 0.995 0.0257 3967 26715 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.02 0.918 – 1.14 0.664 345 3441 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.977 0.925 – 1.03 0.407 1431 14130 all phecode
471 Nasal polyps Respiratory 0.884 0.804 – 0.971 0.0103 475 4727 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.954 0.902 – 1.01 0.101 1344 13251 all phecode
473 Diseases of the larynx and vocal cords Respiratory 0.96 0.92 – 1 0.0611 2393 20985 all phecode
473.1 Chronic laryngitis Respiratory 0.879 0.674 – 1.15 0.34 57 562 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.978 0.892 – 1.07 0.638 517 5167 all phecode
473.4 Voice disturbance Respiratory 0.968 0.923 – 1.02 0.187 1880 18033 all phecode
474 Acute and chronic tonsillitis Respiratory 0.959 0.886 – 1.04 0.299 685 6193 all phecode
474.1 Acute tonsillitis Respiratory 0.954 0.839 – 1.08 0.472 267 2507 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.959 0.878 – 1.05 0.354 555 5166 all phecode
475 Chronic sinusitis Respiratory 0.938 0.905 – 0.973 0.000559 3434 23149 all phecode
475.9 Postnasal drip Respiratory 0.939 0.866 – 1.02 0.128 651 6441 all phecode
476 Allergic rhinitis Respiratory 0.974 0.951 – 0.997 0.0262 10205 23354 all phecode
477 Epistaxis or throat hemorrhage Respiratory 0.982 0.916 – 1.05 0.601 895 8841 all phecode
478 Throat pain Respiratory 0.988 0.882 – 1.11 0.842 325 3233 all phecode
479 Other upper respiratory disease Respiratory 0.974 0.943 – 1.01 0.115 4428 23338 all phecode
480 Pneumonia Respiratory 0.974 0.945 – 1 0.0935 4823 30881 all phecode
480.1 Bacterial pneumonia Respiratory 0.935 0.871 – 1 0.0602 860 8567 all phecode
480.11 Pneumococcal pneumonia Respiratory 0.992 0.894 – 1.1 0.887 372 3720 all phecode
480.12 Pseudomonal pneumonia Respiratory 0.801 0.666 – 0.963 0.0185 121 1192 all phecode
480.13 MRSA pneumonia Respiratory 0.895 0.714 – 1.12 0.337 82 818 all phecode
480.2 Viral pneumonia Respiratory 0.959 0.807 – 1.14 0.637 147 1461 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.949 0.792 – 1.14 0.57 117 1170 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1 0.832 – 1.21 0.982 119 1175 all phecode
481 Influenza Respiratory 0.924 0.864 – 0.987 0.0196 990 9863 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.945 0.908 – 0.984 0.00647 2615 24227 all phecode
495 Asthma Respiratory 0.973 0.948 – 1 0.047 6951 27725 all phecode
495.1 Chronic obstructive asthma Respiratory 0.935 0.835 – 1.05 0.239 341 3403 all phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 0.768 0.588 – 1 0.0525 60 592 all phecode
495.2 Asthma with exacerbation Respiratory 0.956 0.901 – 1.01 0.131 1251 12442 all phecode
496 Chronic airway obstruction Respiratory 0.971 0.94 – 1 0.0714 4444 23893 all phecode
496.1 Emphysema Respiratory 0.973 0.927 – 1.02 0.266 1831 16712 all phecode
496.2 Chronic bronchitis Respiratory 0.981 0.946 – 1.02 0.302 3357 22668 all phecode
496.21 Obstructive chronic bronchitis Respiratory 0.98 0.943 – 1.02 0.307 3040 21701 all phecode
496.3 Bronchiectasis Respiratory 0.94 0.851 – 1.04 0.219 435 4329 all phecode
497 Bronchitis Respiratory 0.983 0.932 – 1.04 0.543 1481 14700 all phecode
498 Acute bronchospasm Respiratory 0.944 0.849 – 1.05 0.291 376 3745 all phecode
499 Cystic fibrosis Respiratory 0.903 0.745 – 1.1 0.302 116 1160 all phecode
500 Lung disease due to external agents Respiratory 1.08 0.979 – 1.19 0.124 428 4273 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.06 0.847 – 1.33 0.61 81 810 all phecode
500.2 Pneumoconiosis Respiratory 1.1 0.852 – 1.42 0.463 65 640 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 0.908 0.828 – 0.995 0.0394 514 5078 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.949 0.874 – 1.03 0.212 623 6192 all phecode
503 Pulmonary congestion and hypostasis Respiratory 0.946 0.875 – 1.02 0.166 690 6875 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.01 0.917 – 1.11 0.845 447 4454 all phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 0.929 0.816 – 1.06 0.261 247 2456 all phecode
505 Other pulmonary inflamation or edema Respiratory 0.931 0.88 – 0.985 0.0124 1352 13261 all phecode
506 Empyema and pneumothorax Respiratory 0.959 0.921 – 0.999 0.0463 2588 22332 all phecode
507 Pleurisy; pleural effusion Respiratory 0.977 0.936 – 1.02 0.274 2415 21828 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.963 0.92 – 1.01 0.114 2005 19256 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.97 0.933 – 1.01 0.111 3044 23898 all phecode
509.1 Respiratory failure Respiratory 0.938 0.889 – 0.991 0.0215 1466 14560 all phecode
509.2 Respiratory insufficiency Respiratory 0.943 0.882 – 1.01 0.088 928 9238 all phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 0.956 0.906 – 1.01 0.0952 1500 14783 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.976 0.909 – 1.05 0.509 848 8472 all phecode
510 Other diseases of lung Respiratory 0.999 0.968 – 1.03 0.95 4671 30168 all phecode
510.2 Lung transplant Respiratory 0.899 0.746 – 1.08 0.262 128 1274 all phecode
512 Other symptoms of respiratory system Respiratory 0.957 0.938 – 0.978 4.55e-05 14878 23476 all phecode
512.1 Wheezing Respiratory 0.968 0.909 – 1.03 0.317 1071 10626 all phecode
512.2 Painful respiration Respiratory 0.934 0.889 – 0.98 0.00599 1765 17029 all phecode
512.3 Abnormal chest sounds Respiratory 0.953 0.833 – 1.09 0.477 229 2261 all phecode
512.7 Shortness of breath Respiratory 0.963 0.938 – 0.988 0.00417 7928 23452 all phecode
512.8 Cough Respiratory 0.95 0.925 – 0.976 0.000181 7280 23469 all phecode
512.9 Other dyspnea Respiratory 0.958 0.935 – 0.983 0.000878 8658 23467 all phecode
513 Respiratory abnormalities Respiratory 0.968 0.946 – 0.99 0.00522 10231 28110 all phecode
513.3 Hypoventilation Respiratory 0.904 0.833 – 0.982 0.0168 618 6146 all phecode
513.31 Apnea Respiratory 0.902 0.804 – 1.01 0.0806 314 3136 all phecode
513.32 Orthopnea Respiratory 0.88 0.753 – 1.03 0.108 167 1662 all phecode
513.4 Hyperventilation Respiratory 1.01 0.917 – 1.11 0.833 440 4383 all phecode
513.8 Disorders of diaphragm Respiratory 1.06 0.921 – 1.22 0.412 206 2053 all phecode
514 Abnormal findings examination of lungs Respiratory 1 0.97 – 1.03 0.951 4486 29229 all phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 0.956 0.827 – 1.11 0.549 193 1914 all phecode
514.2 Solitary pulmonary nodule Respiratory 1.01 0.967 – 1.05 0.701 2489 22668 all phecode
516 Abnormal sputum Respiratory 0.967 0.886 – 1.05 0.445 565 5640 all phecode
516.1 Hemoptysis Respiratory 0.981 0.892 – 1.08 0.685 473 4720 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.974 0.946 – 1 0.0846 5153 32053 all phecode
519.1 Tracheostomy complications Respiratory 0.835 0.715 – 0.976 0.0238 176 1760 all phecode
519.2 Respiratory complications Respiratory 0.992 0.89 – 1.11 0.888 370 3696 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.951 0.887 – 1.02 0.157 887 8857 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.961 0.93 – 0.994 0.0192 4043 29199 all phecode
520 Disorders of tooth development Digestive 0.94 0.834 – 1.06 0.313 291 2900 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.932 0.782 – 1.11 0.427 131 1301 all phecode
520.2 Disturbances in tooth eruption Digestive 0.943 0.807 – 1.1 0.464 172 1693 all phecode
521 Diseases of hard tissues of teeth Digestive 0.988 0.916 – 1.07 0.763 719 7167 all phecode
521.1 Dental caries Digestive 0.997 0.922 – 1.08 0.947 673 6709 all phecode
522 Diseases of pulp and periapical tissues Digestive 0.972 0.88 – 1.07 0.578 408 4067 all phecode
522.5 Periapical abscess Digestive 0.945 0.847 – 1.05 0.311 341 3404 all phecode
523 Gingival and periodontal diseases Digestive 1.01 0.929 – 1.1 0.807 569 5690 all phecode
523.1 Gingivitis Digestive 0.96 0.797 – 1.16 0.666 117 1163 all phecode
523.3 Periodontitis (acute or chronic) Digestive 0.918 0.817 – 1.03 0.146 294 2940 all phecode
523.31 Acute periodontitis Digestive 0.959 0.846 – 1.09 0.51 251 2510 all phecode
523.32 Chronic periodontitis Digestive 0.832 0.679 – 1.02 0.0762 103 1030 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.953 0.847 – 1.07 0.428 308 3080 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.02 0.873 – 1.19 0.818 186 1856 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.01 0.939 – 1.08 0.823 853 8530 all phecode
525.1 Loss of teeth or edentulism Digestive 0.914 0.814 – 1.03 0.13 318 3178 all phecode
526 Diseases of the jaws Digestive 0.979 0.936 – 1.02 0.358 2140 21162 all phecode
526.1 Cysts of the jaws Digestive 0.958 0.829 – 1.11 0.559 213 2123 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.997 0.862 – 1.15 0.965 206 2052 all phecode
526.4 Temporomandibular joint disorders Digestive 0.983 0.925 – 1.04 0.573 1178 11779 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.999 0.934 – 1.07 0.981 941 9410 all phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 1.01 0.928 – 1.1 0.823 600 5993 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.879 0.771 – 1 0.052 242 2405 all phecode
526.9 Jaw disease NOS Digestive 1.02 0.925 – 1.14 0.638 399 3982 all phecode
527 Diseases of the salivary glands Digestive 0.976 0.923 – 1.03 0.403 1362 13604 all phecode
527.2 Sialoadenitis Digestive 0.925 0.825 – 1.04 0.185 320 3200 all phecode
527.7 Disturbance of salivary secretion Digestive 1.01 0.94 – 1.1 0.71 715 7141 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.03 0.894 – 1.19 0.67 196 1960 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.963 0.92 – 1.01 0.1 2077 20750 all phecode
528.1 Stomatitis and mucositis Digestive 0.953 0.872 – 1.04 0.298 536 5360 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.856 0.727 – 1.01 0.0601 165 1650 all phecode
528.12 Oral aphthae Digestive 0.943 0.805 – 1.11 0.472 170 1700 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.938 0.804 – 1.09 0.414 185 1837 all phecode
528.4 Cysts of oral soft tissues Digestive 0.953 0.789 – 1.15 0.615 110 1096 all phecode
528.41 Cyst of the salivary gland Digestive 1.09 0.86 – 1.38 0.478 68 679 all phecode
528.5 Diseases of lips Digestive 1.11 0.989 – 1.24 0.0758 334 3340 all phecode
528.6 Leukoplakia of oral mucosa Digestive 0.904 0.75 – 1.09 0.293 113 1120 all phecode
528.7 Sialolithiasis Digestive 0.825 0.691 – 0.985 0.0332 132 1320 all phecode
529 Diseases and other conditions of the tongue Digestive 0.954 0.873 – 1.04 0.293 541 5402 all phecode
529.1 Glossitis Digestive 0.928 0.749 – 1.15 0.496 99 982 all phecode
529.6 Glossodynia Digestive 0.974 0.816 – 1.16 0.775 136 1355 all phecode
530 Diseases of esophagus Digestive 0.97 0.949 – 0.991 0.0057 13874 23034 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.971 0.95 – 0.993 0.00841 13419 23031 all phecode
530.11 GERD Digestive 0.97 0.949 – 0.992 0.00722 13059 23031 all phecode
530.12 Ulcer of esophagus Digestive 0.925 0.82 – 1.04 0.203 298 2973 all phecode
530.13 Barrett's esophagus Digestive 0.959 0.882 – 1.04 0.332 609 6080 all phecode
530.14 Reflux esophagitis Digestive 0.944 0.894 – 0.996 0.0347 1483 14213 all phecode
530.15 Eosinophilic esophagitis Digestive 0.975 0.823 – 1.16 0.771 145 1441 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.959 0.872 – 1.05 0.384 475 4742 all phecode
530.3 Stricture and stenosis of esophagus Digestive 0.952 0.883 – 1.03 0.203 752 7474 all phecode
530.5 Disorders of esophageal motility Digestive 0.984 0.891 – 1.09 0.748 434 4326 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.807 0.666 – 0.978 0.0283 121 1181 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.928 0.726 – 1.19 0.552 70 700 all phecode
530.9 Heartburn Digestive 0.989 0.932 – 1.05 0.72 1198 11946 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.03 0.974 – 1.08 0.342 1608 16066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.08 0.958 – 1.21 0.214 311 3103 all phecode
531.2 Gastric ulcer Digestive 0.981 0.915 – 1.05 0.596 884 8834 all phecode
531.3 Duodenal ulcer Digestive 1.08 0.967 – 1.2 0.174 362 3613 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.05 0.966 – 1.14 0.259 632 6313 all phecode
531.5 Gastrojejunal ulcer Digestive 1.2 0.985 – 1.46 0.07 115 1143 all phecode
532 Dysphagia Digestive 0.963 0.932 – 0.995 0.0257 4457 22190 all phecode
535 Gastritis and duodenitis Digestive 0.94 0.898 – 0.983 0.00679 2129 21208 all phecode
535.1 Acute gastritis Digestive 0.957 0.89 – 1.03 0.239 814 8139 all phecode
535.2 Atrophic gastritis Digestive 0.938 0.824 – 1.07 0.34 250 2500 all phecode
535.6 Duodenitis Digestive 0.897 0.79 – 1.02 0.0954 265 2650 all phecode
535.8 Other specified gastritis Digestive 0.933 0.85 – 1.02 0.147 497 4964 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.924 0.865 – 0.987 0.0188 985 9835 all phecode
536 Disorders of function of stomach Digestive 0.958 0.917 – 1 0.0544 2251 22311 all phecode
536.3 Gastroparesis Digestive 0.952 0.868 – 1.04 0.294 489 4876 all phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 0.981 0.876 – 1.1 0.733 334 3331 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.958 0.912 – 1.01 0.0957 1699 16834 all phecode
537 Other disorders of stomach and duodenum Digestive 0.97 0.929 – 1.01 0.159 2357 23199 all phecode
537.1 Lesions of stomach and duodenum Digestive 0.91 0.758 – 1.09 0.313 128 1271 all phecode
539 Bariatric surgery Digestive 0.928 0.872 – 0.987 0.0184 1118 11180 all phecode
540 Appendiceal conditions Digestive 0.978 0.882 – 1.08 0.666 399 3990 all phecode
540.1 Appendicitis Digestive 0.965 0.865 – 1.08 0.519 349 3490 all phecode
540.11 Acute appendicitis Digestive 0.944 0.837 – 1.06 0.343 293 2930 all phecode
550 Abdominal hernia Digestive 0.987 0.959 – 1.02 0.373 5517 31191 all phecode
550.1 Inguinal hernia Digestive 0.969 0.917 – 1.02 0.265 1427 13556 all phecode
550.2 Diaphragmatic hernia Digestive 1.03 0.984 – 1.07 0.218 2290 21266 all phecode
550.3 Femoral hernia Digestive 0.982 0.805 – 1.2 0.858 109 1082 all phecode
550.4 Umbilical hernia Digestive 0.913 0.857 – 0.973 0.00513 1053 10514 all phecode
550.5 Ventral hernia Digestive 0.997 0.95 – 1.05 0.891 1826 18190 all phecode
550.6 Incisional hernia Digestive 0.988 0.928 – 1.05 0.709 1101 10999 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.04 0.978 – 1.1 0.224 1275 12527 all phecode
555.1 Regional enteritis Digestive 1.04 0.969 – 1.12 0.26 775 7701 all phecode
555.2 Ulcerative colitis Digestive 1.06 0.984 – 1.14 0.125 768 7591 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.07 0.969 – 1.18 0.181 438 4361 all phecode
556 Ulceration of the lower GI tract Digestive 0.913 0.83 – 1.01 0.0645 473 4719 all phecode
556.1 Ulceration of intestine Digestive 0.919 0.829 – 1.02 0.105 412 4099 all phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 0.972 0.829 – 1.14 0.731 152 1496 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.94 0.887 – 0.995 0.0339 1306 12565 all phecode
557.1 Celiac disease Digestive 0.988 0.879 – 1.11 0.839 305 3050 all phecode
558 Noninfectious gastroenteritis Digestive 1.02 0.978 – 1.06 0.372 2706 20417 all phecode
559 Ileostomy status Digestive 0.959 0.89 – 1.03 0.269 773 7702 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.01 0.972 – 1.06 0.529 2580 20303 all phecode
560.1 Paralytic ileus Digestive 1.05 0.99 – 1.1 0.113 1429 13524 all phecode
560.2 Impaction of intestine Digestive 0.923 0.809 – 1.05 0.231 257 2499 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.04 0.92 – 1.19 0.503 261 2599 all phecode
560.4 Other intestinal obstruction Digestive 1 0.951 – 1.06 0.91 1489 14381 all phecode
561 Symptoms involving digestive system Digestive 0.987 0.961 – 1.01 0.322 7750 22039 all phecode
561.1 Diarrhea Digestive 0.994 0.965 – 1.02 0.664 5986 22042 all phecode
561.2 Flatulence Digestive 0.973 0.932 – 1.02 0.22 2358 18995 all phecode
562 Diverticulosis and diverticulitis Digestive 0.986 0.954 – 1.02 0.382 5014 18500 all phecode
562.1 Diverticulosis Digestive 0.988 0.957 – 1.02 0.466 4973 18448 all phecode
562.2 Diverticulitis Digestive 0.986 0.931 – 1.04 0.629 1292 12242 all phecode
563 Constipation Digestive 0.99 0.961 – 1.02 0.49 5639 22004 all phecode
564 Functional digestive disorders Digestive 0.984 0.96 – 1.01 0.188 9553 22037 all phecode
564.1 Irritable Bowel Syndrome Digestive 1 0.961 – 1.04 0.985 2751 17147 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 0.993 0.95 – 1.04 0.734 2348 18710 all phecode
564.9 Personal history of diseases of digestive system Digestive 0.976 0.928 – 1.03 0.327 1762 16521 all phecode
565 Anal and rectal conditions Digestive 1 0.964 – 1.05 0.848 2533 24500 all phecode
565.1 Anal and rectal polyp Digestive 1 0.934 – 1.07 0.993 932 9300 all phecode
567 Peritonitis and retroperitoneal infections Digestive 0.983 0.925 – 1.04 0.581 1149 11482 all phecode
568 Other disorders of peritoneum Digestive 1 0.949 – 1.06 0.952 1452 14494 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.03 0.968 – 1.1 0.356 1076 10752 all phecode
569 Other disorders of intestine Digestive 0.98 0.954 – 1.01 0.154 6343 29512 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.976 0.858 – 1.11 0.71 251 2510 all phecode
569.2 Gastrointestinal complications Digestive 0.972 0.915 – 1.03 0.34 1206 12058 all phecode
571 Chronic liver disease and cirrhosis Digestive 0.974 0.941 – 1.01 0.138 3603 27394 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 0.976 0.942 – 1.01 0.187 3388 27100 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.966 0.897 – 1.04 0.351 781 7802 all phecode
571.6 Primary biliary cirrhosis Digestive 0.927 0.783 – 1.1 0.378 146 1460 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.964 0.894 – 1.04 0.333 749 7472 all phecode
571.81 Portal hypertension Digestive 0.946 0.858 – 1.04 0.267 441 4400 all phecode
572 Ascites (non malignant) Digestive 1.01 0.965 – 1.06 0.629 1884 18805 all phecode
573 Other disorders of liver Digestive 0.993 0.962 – 1.02 0.661 4460 28151 all phecode
573.1 Chronic passive congestion of liver Digestive 0.85 0.687 – 1.05 0.132 100 991 all phecode
573.2 Liver replaced by transplant Digestive 1 0.875 – 1.15 0.966 227 2268 all phecode
573.3 Hepatomegaly Digestive 0.922 0.824 – 1.03 0.155 337 3368 all phecode
573.4 Acute and subacute necrosis of liver Digestive 0.885 0.778 – 1.01 0.0644 258 2580 all phecode
573.5 Jaundice (not of newborn) Digestive 0.994 0.922 – 1.07 0.878 758 7555 all phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 0.991 0.946 – 1.04 0.71 1973 19683 all phecode
573.7 Abnormal results of function study of liver Digestive 0.977 0.935 – 1.02 0.319 2110 21014 all phecode
573.9 Abnormal serum enzyme levels Digestive 1 0.969 – 1.04 0.8 3345 28043 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.01 0.967 – 1.05 0.744 2610 25589 all phecode
574.1 Cholelithiasis Digestive 0.988 0.947 – 1.03 0.56 2391 23829 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.03 0.903 – 1.17 0.679 260 2580 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.01 0.916 – 1.11 0.853 444 4434 all phecode
574.2 Calculus of bile duct Digestive 0.992 0.917 – 1.07 0.835 696 6939 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.998 0.921 – 1.08 0.955 667 6662 all phecode
575 Other biliary tract disease Digestive 0.98 0.934 – 1.03 0.401 1868 18668 all phecode
575.1 Cholangitis Digestive 0.938 0.833 – 1.06 0.294 310 3089 all phecode
575.2 Obstruction of bile duct Digestive 0.931 0.85 – 1.02 0.127 530 5291 all phecode
575.6 Cholesterolosis of gallbladder Digestive 1.05 0.902 – 1.22 0.531 168 1680 all phecode
575.7 Other disorders of gallbladder Digestive 0.994 0.923 – 1.07 0.869 773 7719 all phecode
575.8 Other disorders of biliary tract Digestive 0.934 0.875 – 0.997 0.0399 996 9950 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.14 0.985 – 1.32 0.0794 188 1880 all phecode
577 Diseases of pancreas Digestive 0.959 0.914 – 1.01 0.0925 1842 18379 all phecode
577.1 Acute pancreatitis Digestive 0.972 0.91 – 1.04 0.409 967 9651 all phecode
577.2 Chronic pancreatitis Digestive 0.924 0.834 – 1.02 0.134 396 3955 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.951 0.864 – 1.05 0.309 462 4557 all phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.974 – 1.04 0.636 3572 30460 all phecode
578.1 Hematemesis Digestive 0.931 0.838 – 1.03 0.185 383 3821 all phecode
578.2 Blood in stool Digestive 1 0.958 – 1.05 0.937 2156 21196 all phecode
578.8 Hemorrhage of rectum and anus Digestive 0.992 0.944 – 1.04 0.759 1718 17070 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.983 0.927 – 1.04 0.558 1238 12280 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.988 0.955 – 1.02 0.502 3750 28690 all phecode
579.2 Splenomegaly Digestive 0.926 0.85 – 1.01 0.0764 593 5923 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.963 0.902 – 1.03 0.263 998 9882 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.942 0.889 – 0.999 0.0451 1264 12626 all phecode
580.1 Glomerulonephritis Genitourinary 0.962 0.86 – 1.08 0.5 324 3228 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.974 0.803 – 1.18 0.788 114 1140 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.941 0.757 – 1.17 0.586 92 905 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.95 0.832 – 1.09 0.45 232 2298 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.02 0.874 – 1.2 0.769 167 1670 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.942 0.881 – 1.01 0.0861 943 9430 all phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 0.923 0.844 – 1.01 0.0805 554 5535 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.996 0.91 – 1.09 0.939 500 4995 all phecode
580.4 Renal sclerosis, NOS Genitourinary 1.01 0.89 – 1.14 0.887 275 2750 all phecode
585 Renal failure Genitourinary 0.962 0.934 – 0.99 0.00939 5756 27307 all phecode
585.1 Acute renal failure Genitourinary 0.972 0.936 – 1.01 0.129 3278 22851 all phecode
585.2 Renal failure NOS Genitourinary 0.984 0.91 – 1.06 0.677 688 6872 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.964 0.932 – 0.997 0.0318 4216 24655 all phecode
585.31 Renal dialysis Genitourinary 0.976 0.894 – 1.07 0.593 543 5430 all phecode
585.32 End stage renal disease Genitourinary 0.971 0.902 – 1.05 0.44 773 7730 all phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 0.965 0.923 – 1.01 0.113 2272 17155 all phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 0.98 0.907 – 1.06 0.603 707 7038 all phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 0.982 0.915 – 1.05 0.612 851 8381 all phecode
586 Other disorders of the kidney and ureters Genitourinary 0.98 0.953 – 1.01 0.168 6202 28774 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.01 0.895 – 1.14 0.855 284 2825 all phecode
586.11 Small kidney Genitourinary 1.01 0.856 – 1.19 0.918 165 1642 all phecode
586.12 Vesicoureteral reflux Genitourinary 0.912 0.751 – 1.11 0.349 112 1120 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.05 0.989 – 1.12 0.111 1170 11069 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.02 0.862 – 1.21 0.802 148 1470 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.988 0.937 – 1.04 0.65 1536 14675 all phecode
587 Kidney replaced by transpant Genitourinary 0.998 0.918 – 1.08 0.956 612 6120 all phecode
588 Disorders resulting from impaired renal function Genitourinary 0.968 0.894 – 1.05 0.414 701 7004 all phecode
588.1 Renal osteodystrophy Genitourinary 1.08 0.943 – 1.24 0.26 227 2267 all phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 0.982 0.896 – 1.08 0.693 525 5241 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.01 0.943 – 1.09 0.721 840 8370 all phecode
590 Pyelonephritis Genitourinary 0.985 0.927 – 1.05 0.611 1161 11597 all phecode
591 Urinary tract infection Genitourinary 0.96 0.936 – 0.985 0.00173 8020 27291 all phecode
592 Cystitis and urethritis Genitourinary 0.976 0.934 – 1.02 0.269 2264 19423 all phecode
592.1 Cystitis Genitourinary 0.971 0.929 – 1.02 0.204 2149 18531 all phecode
592.11 Acute cystitis Genitourinary 0.965 0.91 – 1.02 0.226 1256 12111 all phecode
592.12 Chronic cystitis Genitourinary 1.02 0.881 – 1.17 0.823 199 1972 all phecode
592.13 Chronic interstitial cystitis Genitourinary 1.03 0.924 – 1.15 0.585 354 3540 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.02 0.851 – 1.21 0.866 143 1430 all phecode
593 Hematuria Genitourinary 0.95 0.918 – 0.983 0.00352 3848 26566 all phecode
593.1 Gross hematuria Genitourinary 0.902 0.849 – 0.958 0.000788 1201 11351 all phecode
593.2 Microscopic hematuria Genitourinary 0.993 0.919 – 1.07 0.853 724 7225 all phecode
594 Urinary calculus Genitourinary 1 0.974 – 1.03 0.892 5516 31876 all phecode
594.1 Calculus of kidney Genitourinary 0.999 0.97 – 1.03 0.967 5155 31730 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.03 0.914 – 1.15 0.649 310 3068 all phecode
594.3 Calculus of ureter Genitourinary 0.961 0.904 – 1.02 0.21 1104 11000 all phecode
594.8 Renal colic Genitourinary 0.98 0.869 – 1.11 0.741 286 2851 all phecode
595 Hydronephrosis Genitourinary 0.957 0.905 – 1.01 0.117 1410 14092 all phecode
596 Other disorders of bladder Genitourinary 0.981 0.941 – 1.02 0.362 2527 23338 all phecode
596.1 Bladder neck obstruction Genitourinary 0.879 0.785 – 0.985 0.0258 333 3288 all phecode
596.5 Functional disorders of bladder Genitourinary 0.95 0.898 – 1 0.0721 1368 13608 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.938 0.88 – 1 0.049 1041 10322 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.897 0.825 – 0.975 0.0106 608 6024 all phecode
597.2 Urinary complications NEC Genitourinary 0.93 0.867 – 0.998 0.0428 861 8600 all phecode
597.8 Urethral hypermobility/ISD Genitourinary 0.951 0.808 – 1.12 0.541 158 1578 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.02 0.963 – 1.08 0.491 1263 12596 all phecode
598.4 Other cells and casts in urine Genitourinary 1.08 0.875 – 1.34 0.46 91 906 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.02 0.963 – 1.08 0.487 1234 12317 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.964 0.942 – 0.986 0.00162 11346 25364 all phecode
599.1 Urinary obstruction Genitourinary 0.924 0.847 – 1.01 0.072 580 5634 all phecode
599.2 Retention of urine Genitourinary 0.98 0.948 – 1.01 0.239 4234 24058 all phecode
599.3 Dysuria Genitourinary 0.957 0.923 – 0.993 0.0191 3426 23180 all phecode
599.4 Urinary incontinence Genitourinary 0.967 0.936 – 0.999 0.0433 4566 22567 all phecode
599.5 Frequency of urination and polyuria Genitourinary 0.96 0.929 – 0.992 0.0158 4277 23742 all phecode
599.6 Oliguria and anuria Genitourinary 1.05 0.957 – 1.15 0.304 513 5104 all phecode
599.7 Urethral discharge Genitourinary 1.22 0.977 – 1.53 0.0798 83 830 all phecode
599.8 Other symptoms involving urinary system Genitourinary 0.943 0.912 – 0.975 0.000509 4366 23262 all phecode
599.9 Other abnormality of urination Genitourinary 0.97 0.929 – 1.01 0.162 2349 20289 all phecode
600 Hyperplasia of prostate Genitourinary 0.947 0.907 – 0.988 0.0111 3315 9437 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.942 0.876 – 1.01 0.102 825 7745 all phecode
601.1 Prostatitis Genitourinary 0.99 0.891 – 1.1 0.848 378 3680 all phecode
601.11 Acute prostatitis Genitourinary 0.993 0.806 – 1.22 0.948 95 933 all phecode
601.12 Chronic prostatitis Genitourinary 0.992 0.789 – 1.25 0.943 76 757 all phecode
601.3 Orchitis and epididymitis Genitourinary 0.968 0.861 – 1.09 0.588 303 3008 all phecode
601.4 Balanoposthitis Genitourinary 0.836 0.683 – 1.02 0.083 103 1019 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.863 0.716 – 1.04 0.121 125 1226 all phecode
602 Other disorders of prostate Genitourinary 0.867 0.764 – 0.984 0.0272 277 2673 all phecode
603 Other disorders of testis Genitourinary 0.918 0.821 – 1.03 0.132 348 3468 all phecode
603.1 Hydrocele Genitourinary 0.855 0.745 – 0.98 0.0246 229 2281 all phecode
603.2 Spermatocele Genitourinary 0.981 0.816 – 1.18 0.84 126 1258 all phecode
604 Disorders of penis Genitourinary 0.876 0.8 – 0.958 0.00384 536 5321 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.732 0.609 – 0.879 0.000847 130 1297 all phecode
604.3 Peyronie's disease Genitourinary 0.907 0.774 – 1.06 0.231 171 1703 all phecode
605 Erectile dysfunction [ED] Genitourinary 0.933 0.894 – 0.973 0.00115 2844 10666 all phecode
608 Other disorders of male genital organs Genitourinary 0.975 0.921 – 1.03 0.394 1302 11530 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.11 0.993 – 1.24 0.0671 335 3350 all phecode
609.1 Infertility, male Genitourinary 1.04 0.913 – 1.19 0.526 242 2420 all phecode
609.11 Azoospermia and oligospermia Genitourinary 1.04 0.826 – 1.32 0.716 79 789 all phecode
609.2 Abnormal spermatozoa Genitourinary 1.27 1.05 – 1.53 0.0141 119 1185 all phecode
610 Benign mammary dysplasias Genitourinary 0.951 0.914 – 0.989 0.012 3089 13905 all phecode
610.1 Cystic mastopathy Genitourinary 0.932 0.88 – 0.986 0.0142 1361 12011 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.941 0.901 – 0.984 0.00712 2400 13828 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.955 0.895 – 1.02 0.158 1047 10149 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.947 0.917 – 0.979 0.00123 4952 15509 all phecode
611.1 Abnormal mammogram Genitourinary 0.952 0.919 – 0.986 0.00666 4074 13538 all phecode
611.11 Mammographic microcalcification Genitourinary 0.929 0.869 – 0.993 0.0296 962 9131 all phecode
611.3 Lump or mass in breast Genitourinary 0.956 0.919 – 0.995 0.0277 3011 15449 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.912 0.851 – 0.978 0.00994 879 8768 all phecode
612.1 Galactorrhea Genitourinary 0.976 0.803 – 1.18 0.803 109 1083 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.889 0.821 – 0.962 0.0036 672 6710 all phecode
612.3 Congenital anomalies of breast Genitourinary 0.896 0.701 – 1.14 0.379 70 676 all phecode
613 Other nonmalignant breast conditions Genitourinary 0.972 0.936 – 1.01 0.142 3180 18154 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.03 0.941 – 1.13 0.517 504 5035 all phecode
613.5 Mastodynia Genitourinary 0.963 0.909 – 1.02 0.192 1313 12942 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.945 0.875 – 1.02 0.15 722 7109 all phecode
613.8 Other specified disorders of breast Genitourinary 1 0.933 – 1.08 0.934 800 7961 all phecode
613.9 Breast disorder NOS Genitourinary 0.968 0.912 – 1.03 0.282 1211 11947 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.977 0.939 – 1.02 0.253 2990 16271 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.89 0.785 – 1.01 0.0707 267 2670 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.924 0.833 – 1.03 0.139 404 4024 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.816 0.638 – 1.04 0.104 74 720 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.01 0.856 – 1.19 0.929 167 1666 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.03 0.888 – 1.18 0.734 198 1979 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.06 0.884 – 1.27 0.537 129 1290 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.977 0.936 – 1.02 0.285 2546 16112 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.02 0.883 – 1.19 0.753 197 1970 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.961 0.918 – 1.01 0.0869 2201 15690 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.794 0.649 – 0.971 0.0245 104 1040 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.984 0.838 – 1.16 0.847 164 1619 all phecode
615 Endometriosis Genitourinary 1.04 0.978 – 1.1 0.227 1298 12230 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 0.984 0.931 – 1.04 0.57 1415 13522 all phecode
618 Genital prolapse Genitourinary 0.975 0.927 – 1.02 0.317 1707 14626 all phecode
618.1 Prolapse of vaginal walls Genitourinary 0.979 0.921 – 1.04 0.481 1179 11187 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.01 0.917 – 1.11 0.834 444 4418 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.945 0.836 – 1.07 0.357 286 2855 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.937 0.843 – 1.04 0.235 375 3750 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.958 0.927 – 0.991 0.0126 4598 15534 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.966 0.911 – 1.02 0.246 1262 11294 all phecode
619.2 Disorders of uterus, NEC Genitourinary 0.975 0.885 – 1.07 0.613 444 4435 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.918 0.827 – 1.02 0.108 391 3892 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.972 0.926 – 1.02 0.256 1903 15019 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.935 0.872 – 1 0.0554 914 9082 all phecode
620 Dysplasia of female genital organs Genitourinary 0.959 0.854 – 1.08 0.478 325 3234 all phecode
620.1 Dysplasia of cervix Genitourinary 0.934 0.782 – 1.12 0.455 142 1420 all phecode
621 Endometrial hyperplasia Genitourinary 1.03 0.922 – 1.15 0.592 334 3335 all phecode
622 Polyp of female genital organs Genitourinary 0.941 0.886 – 1 0.0484 1191 11723 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.934 0.873 – 0.999 0.047 949 9362 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.969 0.868 – 1.08 0.571 348 3480 all phecode
623 Hypertrophy of female genital organs Genitourinary 0.974 0.896 – 1.06 0.541 605 6003 all phecode
624 Symptoms involving female genital tract Genitourinary 0.947 0.887 – 1.01 0.106 1013 9695 all phecode
624.1 Dystrophy of female genital tract Genitourinary 1.02 0.869 – 1.2 0.813 168 1680 all phecode
624.9 stress incontinence, female Genitourinary 0.971 0.921 – 1.02 0.275 1549 12918 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.924 0.893 – 0.956 5.05e-06 4618 14394 all phecode
625.1 Dyspareunia Genitourinary 0.947 0.887 – 1.01 0.104 1011 10081 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.952 0.92 – 0.986 0.00535 4726 13065 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.941 0.905 – 0.979 0.00246 3426 12112 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.895 0.831 – 0.965 0.00379 802 6948 all phecode
626.12 Excessive or frequent menstruation Genitourinary 0.918 0.871 – 0.967 0.0014 1703 9843 all phecode
626.13 Irregular menstrual cycle Genitourinary 0.97 0.918 – 1.02 0.273 1543 10197 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.933 0.866 – 1.01 0.0697 777 7408 all phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.893 0.791 – 1.01 0.0679 300 3000 all phecode
626.2 Dysmenorrhea Genitourinary 0.907 0.85 – 0.966 0.00264 1116 8297 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.908 0.8 – 1.03 0.136 275 2741 all phecode
626.8 Infertility, female Genitourinary 0.972 0.894 – 1.06 0.51 630 5218 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.946 0.911 – 0.982 0.0034 3657 12296 all phecode
627.1 Postmenopausal bleeding Genitourinary 0.919 0.86 – 0.983 0.0133 957 8768 all phecode
627.2 Symptomatic menopause Genitourinary 0.935 0.895 – 0.977 0.00282 2443 11667 all phecode
627.21 Symptomatic artificial menopause Genitourinary 0.884 0.737 – 1.06 0.181 125 1241 all phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 1.01 0.9 – 1.14 0.829 295 2948 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.937 0.868 – 1.01 0.0919 729 7262 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.884 0.787 – 0.994 0.0401 305 3020 all phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.9 0.785 – 1.03 0.127 234 2340 all phecode
628 Ovarian cyst Genitourinary 0.94 0.892 – 0.992 0.0236 1619 11554 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.973 0.897 – 1.06 0.519 648 6413 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.898 0.778 – 1.04 0.14 209 2090 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.913 0.735 – 1.14 0.415 95 950 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.03 0.927 – 1.14 0.609 414 4070 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.03 0.905 – 1.16 0.686 272 2720 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1 0.87 – 1.16 0.952 206 2060 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.949 0.882 – 1.02 0.166 855 6402 all phecode
636.1 Threatened premature labor Pregnancy Complications 1.01 0.893 – 1.14 0.894 298 2980 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.849 0.74 – 0.975 0.0204 233 2330 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.887 0.792 – 0.993 0.0368 356 3556 all phecode
636.8 Cervical incompetence Pregnancy Complications 1.07 0.826 – 1.39 0.595 60 600 all phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.02 0.823 – 1.26 0.864 89 884 all phecode
638 Other high-risk pregnancy Pregnancy Complications 0.965 0.894 – 1.04 0.348 818 5867 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.856 0.772 – 0.948 0.00287 421 4210 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.905 0.785 – 1.04 0.17 215 2150 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.947 0.811 – 1.1 0.486 181 1810 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.913 0.73 – 1.14 0.425 87 870 all phecode
644 Anemia during pregnancy Pregnancy Complications 0.967 0.821 – 1.14 0.691 154 1540 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.945 0.835 – 1.07 0.374 286 2860 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.902 0.828 – 0.982 0.0178 622 5063 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.968 0.819 – 1.14 0.707 152 1520 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.836 0.718 – 0.975 0.0224 182 1820 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.946 0.883 – 1.01 0.121 968 6387 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.904 0.814 – 1 0.059 413 4130 all phecode
650 Normal delivery Pregnancy Complications 0.937 0.868 – 1.01 0.101 757 6412 all phecode
651 Multiple gestation Pregnancy Complications 0.958 0.779 – 1.18 0.686 100 1000 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1.04 0.94 – 1.14 0.477 461 4586 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.933 0.844 – 1.03 0.177 443 4189 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 0.947 0.86 – 1.04 0.27 482 4820 all phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.933 0.841 – 1.04 0.195 402 4020 all phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 1.02 0.869 – 1.2 0.802 163 1630 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.993 0.934 – 1.06 0.834 1244 8117 all phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 0.944 0.854 – 1.04 0.26 451 4371 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.995 0.871 – 1.14 0.936 246 2460 all phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 1.09 0.833 – 1.42 0.535 59 590 all phecode
658
Maternal complication of pregnancy affecting
Maternal complication of pregnancy affecting fetus or newborn
 Pregnancy Complications 0.848 0.73 – 0.986 0.0316 195 1950 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.983 0.894 – 1.08 0.73 504 4732 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.938 0.846 – 1.04 0.225 420 4080 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.888 0.822 – 0.96 0.00282 751 6161 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.927 0.853 – 1.01 0.0719 671 5265 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.926 0.789 – 1.09 0.344 172 1720 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.952 0.816 – 1.11 0.534 181 1810 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.849 0.703 – 1.02 0.086 122 1220 all phecode
681 Superficial cellulitis and abscess Dermatologic 0.965 0.936 – 0.994 0.0182 5078 31991 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.897 0.835 – 0.963 0.00264 862 8581 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.981 0.911 – 1.06 0.606 781 7775 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.952 0.902 – 1 0.0661 1533 15238 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.93 0.883 – 0.98 0.0061 1649 16359 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.936 0.883 – 0.992 0.0268 1291 12850 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 0.975 0.92 – 1.03 0.399 1238 12342 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 0.983 0.934 – 1.03 0.499 1660 16466 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.07 0.967 – 1.19 0.191 390 3881 all phecode
686.2 Impetigo Dermatologic 0.911 0.812 – 1.02 0.11 310 3068 all phecode
686.3 Pilonidal cyst Dermatologic 1.02 0.845 – 1.24 0.815 120 1200 all phecode
686.4 Pyogenic granuloma Dermatologic 0.886 0.739 – 1.06 0.194 121 1205 all phecode
687 Symptoms affecting skin Dermatologic 0.987 0.959 – 1.01 0.347 6119 25901 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.977 0.948 – 1.01 0.124 5371 25824 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 0.979 0.95 – 1.01 0.169 5264 25870 all phecode
687.3 Changes in skin texture Dermatologic 0.978 0.868 – 1.1 0.721 294 2926 all phecode
687.4 Disturbance of skin sensation Dermatologic 0.991 0.961 – 1.02 0.562 4942 25586 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.09 1.07 – 1.12 1.66e-11 7192 31086 all phecode
690 Erythematosquamous dermatosis Dermatologic 1.07 1.04 – 1.11 3.61e-05 3810 26256 all phecode
690.1 Seborrheic dermatitis Dermatologic 1.08 1.04 – 1.11 3.15e-05 3802 26218 all phecode
691 Congenital anomalies of skin Dermatologic 0.966 0.874 – 1.07 0.495 411 4110 all phecode
694 Dyschromia and Vitiligo Dermatologic 1.08 1.02 – 1.15 0.00639 1286 12819 all phecode
694.1 Vitiligo Dermatologic 0.958 0.775 – 1.18 0.689 94 931 all phecode
694.2 Other dyschromia Dermatologic 1.09 1.03 – 1.16 0.00574 1146 11421 all phecode
694.3 Vascular disorders of skin Dermatologic 1.23 0.958 – 1.58 0.104 69 686 all phecode
695 Erythematous conditions Dermatologic 1.01 0.976 – 1.05 0.484 3180 24642 all phecode
695.2 Bullous dermatoses Dermatologic 0.842 0.653 – 1.09 0.184 68 658 all phecode
695.3 Rosacea Dermatologic 1.04 0.982 – 1.1 0.189 1405 14019 all phecode
695.4 Lupus (localized and systemic) Dermatologic 0.976 0.894 – 1.07 0.594 556 5556 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.868 0.745 – 1.01 0.0694 196 1955 all phecode
695.42 Systemic lupus erythematosus Dermatologic 0.981 0.897 – 1.07 0.673 530 5287 all phecode
695.7 Prurigo and Lichen Dermatologic 0.95 0.86 – 1.05 0.303 429 4275 all phecode
695.8 Other specified erythematous conditions Dermatologic 1.04 0.956 – 1.13 0.372 613 6111 all phecode
695.9 Unspecified erythematous condition Dermatologic 0.995 0.909 – 1.09 0.916 513 5102 all phecode
696 Psoriasis and related disorders Dermatologic 0.898 0.843 – 0.957 0.000892 1080 10781 all phecode
696.3 Pityriasis Dermatologic 0.884 0.682 – 1.15 0.354 64 640 all phecode
696.4 Psoriasis Dermatologic 0.897 0.84 – 0.957 0.00101 1014 10115 all phecode
696.41 Psoriasis vulgaris Dermatologic 0.899 0.839 – 0.963 0.00228 918 9161 all phecode
696.42 Psoriatic arthropathy Dermatologic 0.914 0.795 – 1.05 0.205 225 2250 all phecode
697 Sarcoidosis Dermatologic 0.951 0.841 – 1.07 0.42 265 2650 all phecode
698 Pruritus and related conditions Dermatologic 1.02 0.971 – 1.07 0.406 1686 16680 all phecode
700 Corns and callosities Dermatologic 0.964 0.895 – 1.04 0.329 764 7615 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.02 0.996 – 1.05 0.0901 5838 31889 all phecode
701.1 Keratoderma, acquired Dermatologic 1 0.903 – 1.11 0.972 389 3845 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.16 1.1 – 1.22 7.58e-09 1705 16953 all phecode
701.3 Circumscribed scleroderma Dermatologic 0.993 0.9 – 1.1 0.892 434 4334 all phecode
701.4 Keloid scar Dermatologic 1.08 0.978 – 1.19 0.132 454 4503 all phecode
701.5 Abnormal granulation tissue Dermatologic 0.958 0.855 – 1.07 0.463 328 3260 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.11 1.08 – 1.14 1.05e-11 5351 24908 all phecode
702.1 Actinic keratosis Dermatologic 1.22 1.17 – 1.26 1.32e-24 3236 22206 all phecode
702.2 Seborrheic keratosis Dermatologic 1.08 1.05 – 1.12 1.99e-06 4151 26248 all phecode
702.4 Degenerative skin disorders Dermatologic 1 0.78 – 1.29 0.977 63 624 all phecode
703 Diseases of nail, NOS Dermatologic 0.958 0.899 – 1.02 0.183 1033 10222 all phecode
703.1 Ingrowing nail Dermatologic 0.911 0.836 – 0.992 0.0311 580 5773 all phecode
704 Diseases of hair and hair follicles Dermatologic 0.979 0.937 – 1.02 0.328 2321 22718 all phecode
704.1 Alopecia Dermatologic 0.949 0.89 – 1.01 0.106 1074 10601 all phecode
704.11 Alopecia Areata Dermatologic 0.759 0.575 – 1 0.052 58 580 all phecode
704.2 Hirsutism Dermatologic 1.04 0.905 – 1.19 0.591 227 2263 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.995 0.94 – 1.05 0.875 1286 12791 all phecode
705 Disorders of sweat glands Dermatologic 1 0.908 – 1.11 0.973 439 4376 all phecode
705.1 Dyshidrosis Dermatologic 1.05 0.87 – 1.27 0.617 114 1131 all phecode
705.3 Hidradenitis Dermatologic 0.987 0.848 – 1.15 0.862 183 1815 all phecode
705.8 Hyperhidrosis Dermatologic 1.03 0.961 – 1.11 0.4 846 8429 all phecode
706 Diseases of sebaceous glands Dermatologic 1.02 0.992 – 1.06 0.144 4454 32859 all phecode
706.1 Acne Dermatologic 1 0.956 – 1.05 0.94 1931 17499 all phecode
706.2 Sebaceous cyst Dermatologic 1.02 0.972 – 1.06 0.477 2150 21106 all phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 1.08 1.01 – 1.14 0.0173 1124 11122 all phecode
707 Chronic ulcer of skin Dermatologic 0.964 0.922 – 1.01 0.1 2193 21811 all phecode
707.1 Decubitus ulcer Dermatologic 0.988 0.908 – 1.08 0.777 600 5984 all phecode
707.2 Chronic ulcer of leg or foot Dermatologic 0.954 0.883 – 1.03 0.223 721 7166 all phecode
707.3 Chronic ulcer of unspecified site Dermatologic 0.97 0.917 – 1.03 0.295 1339 13370 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.984 0.925 – 1.05 0.624 1086 10825 all phecode
709.2 Sicca syndrome Dermatologic 1.03 0.928 – 1.15 0.553 365 3650 all phecode
709.3 Systemic sclerosis Dermatologic 1 0.862 – 1.17 0.968 184 1840 all phecode
709.5 Dermatomyositis Dermatologic 0.915 0.717 – 1.17 0.474 70 700 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.04 0.829 – 1.32 0.711 78 780 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.966 0.891 – 1.05 0.398 659 6563 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.927 0.867 – 0.991 0.0251 954 9524 all phecode
710.1 Osteomyelitis Musculoskeletal 0.927 0.866 – 0.992 0.0277 914 9127 all phecode
710.11 Acute osteomyelitis Musculoskeletal 0.911 0.824 – 1.01 0.0705 425 4234 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.01 0.912 – 1.13 0.798 378 3758 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.925 0.863 – 0.992 0.0283 867 8656 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.05 0.935 – 1.18 0.411 314 3124 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.07 0.936 – 1.23 0.309 223 2206 all phecode
712 Infective connective tissue disorders Musculoskeletal 0.939 0.787 – 1.12 0.485 136 1360 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.886 0.77 – 1.02 0.092 222 2214 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 0.851 0.703 – 1.03 0.1 118 1180 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.976 0.927 – 1.03 0.343 1649 14662 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.957 0.905 – 1.01 0.128 1342 12332 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.951 0.89 – 1.02 0.142 979 9761 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.894 0.775 – 1.03 0.123 212 2120 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.922 0.789 – 1.08 0.306 177 1760 all phecode
716 Other arthropathies Musculoskeletal 0.993 0.97 – 1.02 0.53 10893 26011 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.12 0.952 – 1.32 0.17 155 1540 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.928 0.768 – 1.12 0.437 116 1156 all phecode
716.9 Arthropathy NOS Musculoskeletal 0.991 0.969 – 1.01 0.469 10831 26002 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.842 0.731 – 0.969 0.0162 210 2061 all phecode
720 Spinal stenosis Musculoskeletal 0.976 0.941 – 1.01 0.192 3298 24117 all phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 0.981 0.94 – 1.02 0.364 2415 20454 all phecode
721 Spondylosis and allied disorders Musculoskeletal 0.974 0.944 – 1.01 0.109 4494 27007 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.975 0.943 – 1.01 0.129 4206 26584 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.943 0.875 – 1.02 0.125 740 7398 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.03 0.889 – 1.19 0.71 212 2099 all phecode
722 Intervertebral disc disorders Musculoskeletal 0.978 0.95 – 1.01 0.15 5242 28702 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.982 0.946 – 1.02 0.358 3038 26827 all phecode
722.3 Schmorl's nodes Musculoskeletal 0.966 0.802 – 1.16 0.717 115 1140 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.981 0.946 – 1.02 0.303 3338 26140 all phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.04 0.943 – 1.14 0.456 464 4634 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 0.964 0.861 – 1.08 0.526 336 3360 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.986 0.936 – 1.04 0.587 1569 15676 all phecode
723 Other disorders of cervical region Musculoskeletal 0.98 0.91 – 1.06 0.606 761 7610 all phecode
723.1 Torticollis Musculoskeletal 1.1 0.945 – 1.27 0.225 187 1870 all phecode
724 Other and unspecified disorders of back Musculoskeletal 0.958 0.924 – 0.993 0.0205 3338 26730 all phecode
724.1 Disorders of sacrum Musculoskeletal 0.944 0.9 – 0.991 0.021 1804 17663 all phecode
724.2 Disorders of coccyx Musculoskeletal 0.805 0.718 – 0.903 0.000208 331 3290 all phecode
724.8 Other symptoms referable to back Musculoskeletal 0.973 0.903 – 1.05 0.481 753 7499 all phecode
724.9 Other unspecified back disorders Musculoskeletal 0.959 0.904 – 1.02 0.167 1246 12418 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.979 0.955 – 1.01 0.116 7682 25455 all phecode
726.1 Enthesopathy Musculoskeletal 0.971 0.944 – 1 0.0481 5795 25454 all phecode
726.2 Synoviopathy Musculoskeletal 0.988 0.918 – 1.06 0.746 774 7723 all phecode
726.3 Bursitis Musculoskeletal 1.01 0.956 – 1.07 0.681 1339 13090 all phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.978 0.913 – 1.05 0.535 889 8846 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.979 0.951 – 1.01 0.155 5811 25457 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.975 0.934 – 1.02 0.252 2342 20541 all phecode
727.2 Bursitis disorders Musculoskeletal 0.894 0.799 – 1 0.0521 341 3381 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1 0.941 – 1.06 0.969 1109 11034 all phecode
727.5 Rupture of synovium Musculoskeletal 0.889 0.799 – 0.99 0.0323 376 3718 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.956 0.912 – 1 0.0658 1927 18092 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.06 0.971 – 1.16 0.186 520 5187 all phecode
727.8 Plica syndrome Musculoskeletal 1.05 0.867 – 1.27 0.624 115 1117 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.992 0.956 – 1.03 0.644 3433 24951 all phecode
728.1 Muscular calcification and ossification Musculoskeletal 0.996 0.784 – 1.27 0.977 69 682 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.01 0.879 – 1.16 0.899 230 2298 all phecode
728.7 Fasciitis Musculoskeletal 0.943 0.901 – 0.987 0.0117 2056 19042 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.971 0.865 – 1.09 0.61 310 3095 all phecode
729 Other disorders of soft tissues Musculoskeletal 1 0.962 – 1.04 0.908 2618 22751 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.02 0.798 – 1.31 0.868 63 630 all phecode
729.3 Panniculitis Musculoskeletal 0.943 0.765 – 1.16 0.583 100 1000 all phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 0.946 0.716 – 1.25 0.7 53 530 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.05 0.881 – 1.24 0.612 145 1441 all phecode
732 Osteochondropathies Musculoskeletal 1.03 0.916 – 1.17 0.59 289 2882 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.08 0.917 – 1.27 0.359 157 1570 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.9 0.701 – 1.16 0.409 71 710 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.986 0.951 – 1.02 0.453 3481 21966 all phecode
733.2 Cyst of bone Musculoskeletal 0.997 0.844 – 1.18 0.972 162 1613 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.942 0.851 – 1.04 0.249 405 4042 all phecode
733.6 Costochondritis Musculoskeletal 0.906 0.8 – 1.03 0.119 275 2742 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.97 0.898 – 1.05 0.445 701 7003 all phecode
733.9 Chondromalacia Musculoskeletal 0.855 0.68 – 1.07 0.18 80 800 all phecode
735 Acquired foot deformities Musculoskeletal 0.98 0.939 – 1.02 0.335 2431 23304 all phecode
735.1 Flat foot Musculoskeletal 1.02 0.923 – 1.12 0.725 437 4355 all phecode
735.2 Acquired toe deformities Musculoskeletal 0.993 0.926 – 1.07 0.849 869 8616 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.966 0.881 – 1.06 0.464 509 5041 all phecode
735.23 Hallux rigidus Musculoskeletal 1.02 0.903 – 1.14 0.793 299 2975 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.963 0.903 – 1.03 0.249 1039 10308 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.97 0.926 – 1.02 0.191 1997 19771 all phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.933 0.755 – 1.15 0.521 90 892 all phecode
736.2 Acquired deformities of finger Musculoskeletal 0.896 0.766 – 1.05 0.168 169 1684 all phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.942 0.826 – 1.07 0.375 239 2382 all phecode
736.5 Acquired deformities of knee Musculoskeletal 0.956 0.822 – 1.11 0.56 184 1834 all phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.958 0.842 – 1.09 0.516 256 2555 all phecode
737 Curvature of spine Musculoskeletal 1 0.944 – 1.06 0.998 1268 12573 all phecode
737.1 Kyphosis (acquired) Musculoskeletal 1.03 0.932 – 1.15 0.53 383 3819 all phecode
737.2 Lordosis (acquired) Musculoskeletal 0.962 0.745 – 1.24 0.764 65 650 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.986 0.923 – 1.05 0.676 987 9782 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.998 0.952 – 1.05 0.919 1968 19555 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.924 0.861 – 0.991 0.0275 863 8617 all phecode
739 Contracture of joint Musculoskeletal 0.977 0.893 – 1.07 0.61 522 5203 all phecode
740 Osteoarthrosis Musculoskeletal 0.989 0.967 – 1.01 0.317 13133 25195 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.998 0.968 – 1.03 0.893 5329 22764 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.992 0.96 – 1.03 0.637 4543 21500 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.954 0.87 – 1.05 0.312 514 5125 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.01 0.951 – 1.07 0.768 1266 9917 all phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 1.04 0.929 – 1.17 0.479 303 2974 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.992 0.97 – 1.01 0.497 12648 25075 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.978 0.953 – 1 0.108 6764 29838 all phecode
741.1 Ankylosis of joint Musculoskeletal 0.973 0.843 – 1.12 0.703 209 2088 all phecode
741.2 Stiffness of joint Musculoskeletal 0.964 0.904 – 1.03 0.272 995 9908 all phecode
741.3 Difficulty in walking Musculoskeletal 0.949 0.904 – 0.995 0.0317 1854 17778 all phecode
741.4 Joint effusions Musculoskeletal 1.01 0.96 – 1.05 0.81 1930 19185 all phecode
741.5 Hemarthrosis Musculoskeletal 1.08 0.836 – 1.4 0.548 64 640 all phecode
741.6 Villonodular synovitis Musculoskeletal 1.09 0.827 – 1.44 0.542 53 522 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.975 0.941 – 1.01 0.168 3462 27650 all phecode
742.1 Loose body in joint Musculoskeletal 0.897 0.744 – 1.08 0.251 131 1295 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.976 0.855 – 1.11 0.717 243 2414 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.03 0.888 – 1.19 0.724 191 1896 all phecode
742.9 Other derangement of joint Musculoskeletal 0.976 0.941 – 1.01 0.204 3212 26883 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.982 0.956 – 1.01 0.164 7571 30458 all phecode
743.1 Osteoporosis Musculoskeletal 0.987 0.948 – 1.03 0.54 2982 15823 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.986 0.947 – 1.03 0.502 2931 15630 all phecode
743.12 Senile osteoporosis Musculoskeletal 1.01 0.921 – 1.11 0.786 481 4333 all phecode
743.13 Other specified osteoporosis Musculoskeletal 0.95 0.831 – 1.09 0.459 231 2290 all phecode
743.2 Pathologic fracture Musculoskeletal 1.02 0.95 – 1.09 0.599 872 8504 all phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 0.994 0.896 – 1.1 0.911 385 3799 all phecode
743.22 Pathologic fracture of femur Musculoskeletal 0.976 0.812 – 1.17 0.795 116 1143 all phecode
743.4 Stress fracture Musculoskeletal 0.962 0.851 – 1.09 0.532 291 2882 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.975 0.947 – 1 0.0821 5795 29464 all phecode
745 Pain in joint Musculoskeletal 0.982 0.962 – 1 0.0844 15755 22596 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.01 0.963 – 1.06 0.67 1811 18049 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1 0.95 – 1.06 0.921 1446 14417 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1.02 0.934 – 1.12 0.627 519 5181 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.03 0.952 – 1.12 0.443 632 6299 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.981 0.879 – 1.1 0.741 342 3387 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.02 0.917 – 1.13 0.763 402 4014 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.753 0.607 – 0.935 0.0103 93 930 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.03 0.936 – 1.13 0.543 455 4540 all phecode
749.1 Cleft palate Congenital Anomalies 1.04 0.817 – 1.31 0.771 81 791 all phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.993 0.798 – 1.24 0.948 90 897 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.97 0.899 – 1.05 0.426 739 7382 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1 0.889 – 1.12 0.997 307 3069 all phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.957 0.772 – 1.19 0.687 96 944 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1 0.789 – 1.27 0.998 77 767 all phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 1.02 0.848 – 1.23 0.83 121 1210 all phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 0.91 0.687 – 1.2 0.508 57 567 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.963 0.873 – 1.06 0.455 438 4363 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.08 0.948 – 1.22 0.258 262 2613 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.833 0.71 – 0.979 0.0262 180 1790 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.961 0.914 – 1.01 0.126 1682 16764 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.852 0.774 – 0.937 0.000937 491 4897 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.873 0.778 – 0.98 0.0218 328 3280 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.751 0.625 – 0.903 0.00231 132 1301 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.982 0.924 – 1.04 0.554 1139 11355 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.961 0.894 – 1.03 0.287 799 7929 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.956 0.84 – 1.09 0.488 251 2506 all phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.08 0.919 – 1.27 0.344 157 1560 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.958 0.894 – 1.03 0.22 908 9073 all phecode
752.1 Neural tube defects Congenital Anomalies 0.936 0.867 – 1.01 0.0936 728 7277 all phecode
752.11 Spina bifida Congenital Anomalies 1.03 0.866 – 1.22 0.748 144 1440 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1 0.86 – 1.16 0.989 201 2010 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.894 0.754 – 1.06 0.198 146 1451 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.932 0.873 – 0.995 0.036 1006 10049 all phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 0.956 0.788 – 1.16 0.647 116 1155 all phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 0.98 0.89 – 1.08 0.683 470 4675 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.94 0.865 – 1.02 0.144 625 6237 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.941 0.836 – 1.06 0.314 315 3138 all phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 0.736 0.559 – 0.969 0.0289 58 567 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.01 0.892 – 1.15 0.838 258 2580 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.08 0.912 – 1.27 0.378 152 1520 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.946 0.886 – 1.01 0.0897 1021 10203 all phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 1.23 0.927 – 1.63 0.152 55 527 all phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 0.979 0.746 – 1.28 0.879 56 524 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.939 0.824 – 1.07 0.346 246 2459 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.966 0.896 – 1.04 0.367 743 7419 all phecode
757 Congenital anomalies of the integument Congenital Anomalies 1.12 0.993 – 1.26 0.0653 283 2820 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.876 0.733 – 1.05 0.143 134 1334 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.805 0.649 – 0.999 0.049 91 910 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.928 0.846 – 1.02 0.116 498 4964 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.761 0.577 – 1 0.0538 57 567 all phecode
760 Back pain Symptoms 0.984 0.963 – 1 0.131 12687 25663 all phecode
761 Cervicalgia Symptoms 0.985 0.956 – 1.01 0.318 5134 32829 all phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 0.965 0.929 – 1 0.0695 2927 27356 all phecode
764 Sciatica Symptoms 0.94 0.903 – 0.979 0.0028 2623 25291 all phecode
765 Cervical radiculitis Symptoms 1 0.95 – 1.06 0.892 1401 13966 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.987 0.955 – 1.02 0.439 4004 31031 all phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.26 1.02 – 1.57 0.0346 85 835 all phecode
769 Nonallopathic lesions NEC Symptoms 0.967 0.904 – 1.03 0.33 923 9183 all phecode
770 Myalgia and myositis unspecified Symptoms 0.974 0.943 – 1.01 0.112 4324 27592 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.986 0.952 – 1.02 0.425 3638 29710 all phecode
771.1 Swelling of limb Symptoms 0.991 0.96 – 1.02 0.573 4511 29862 all phecode
771.2 Cramp of limb Symptoms 1.04 0.97 – 1.12 0.254 791 7856 all phecode
772 Symptoms of the muscles Symptoms 0.968 0.918 – 1.02 0.228 1549 15345 all phecode
772.1 Muscular wasting and disuse atrophy Symptoms 1.07 0.957 – 1.2 0.231 320 3187 all phecode
772.2 Spasm of muscle Symptoms 0.998 0.95 – 1.05 0.922 1780 17782 all phecode
772.3 Muscle weakness Symptoms 0.955 0.915 – 0.997 0.0358 2339 22770 all phecode
772.4 Rhabdomyolysis Symptoms 1.01 0.838 – 1.23 0.891 117 1170 all phecode
772.6 Facial weakness Symptoms 0.977 0.878 – 1.09 0.665 377 3746 all phecode
773 Pain in limb Symptoms 0.972 0.951 – 0.994 0.0116 11393 26958 all phecode
780 Hypothermia/Chills Symptoms 1.07 0.955 – 1.21 0.233 307 3069 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.982 0.935 – 1.03 0.48 1767 17206 all phecode
781.1 Loss of height Symptoms 1.25 1.01 – 1.55 0.0418 91 890 all phecode
782.3 Edema Symptoms 0.992 0.962 – 1.02 0.634 4591 30849 all phecode
782.6 Pallor and flushing Symptoms 1.04 0.958 – 1.12 0.371 679 6769 all phecode
783 Fever of unknown origin Symptoms 0.976 0.946 – 1.01 0.124 4616 33703 all phecode
783.1 Postprocedural fever Symptoms 0.917 0.805 – 1.04 0.191 248 2473 all phecode
785 Abdominal pain Symptoms 0.987 0.966 – 1.01 0.226 13257 25098 all phecode
788 Syncope and collapse Symptoms 0.985 0.948 – 1.02 0.418 3017 29114 all phecode
789 Nausea and vomiting Symptoms 0.994 0.97 – 1.02 0.616 8497 29838 all phecode
789.1 Persistent vomiting Symptoms 0.977 0.899 – 1.06 0.574 634 6330 all phecode
790 Nonspecific findings on examination of blood Symptoms 0.98 0.933 – 1.03 0.432 1740 17356 all phecode
790.1 Elevated sedimentation rate Symptoms 1.05 0.891 – 1.23 0.567 158 1580 all phecode
790.6 Other abnormal blood chemistry Symptoms 0.987 0.957 – 1.02 0.395 4849 31554 all phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.15 0.996 – 1.33 0.0561 204 2026 all phecode
790.9 Abnormal arterial blood gases Symptoms 0.92 0.764 – 1.11 0.374 123 1230 all phecode
791 Gangrene Symptoms 1.04 0.906 – 1.2 0.561 212 2104 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.949 0.906 – 0.994 0.0283 2171 11972 all phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Symptoms 0.929 0.864 – 0.998 0.0454 841 7806 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.01 0.927 – 1.1 0.837 588 5848 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1 0.951 – 1.05 0.997 1661 16601 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.03 0.934 – 1.14 0.552 433 4330 all phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 0.981 0.932 – 1.03 0.465 1632 15619 all phecode
795.8 Abnormal tumor markers Symptoms 0.972 0.924 – 1.02 0.268 1698 13664 all phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 1.05 0.891 – 1.23 0.574 167 1662 all phecode
796 Elevated prostate specific antigen [PSA] Symptoms 0.936 0.888 – 0.987 0.015 1700 8294 all phecode
797 Shock Symptoms 0.894 0.81 – 0.986 0.0246 445 4446 all phecode
797.1 Cardiogenic shock Symptoms 0.916 0.786 – 1.07 0.258 183 1822 all phecode
798 Malaise and fatigue Symptoms 0.973 0.95 – 0.997 0.0264 8867 29476 all phecode
798.1 Chronic fatigue syndrome Symptoms 0.969 0.916 – 1.03 0.277 1349 13380 all phecode
799 Debility unspecified Symptoms 0.984 0.935 – 1.03 0.527 1672 16007 all phecode
800 Fracture of lower limb Injuries & Poisonings 0.967 0.922 – 1.01 0.173 1879 18684 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.953 0.861 – 1.06 0.354 409 4028 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1 0.915 – 1.09 1 539 5364 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.01 0.934 – 1.08 0.867 744 7420 all phecode
800.4 Fracture of patella Injuries & Poisonings 0.973 0.861 – 1.1 0.657 293 2904 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1 0.957 – 1.05 0.848 1804 17960 all phecode
801.1 Fracture of foot Injuries & Poisonings 0.994 0.928 – 1.06 0.863 913 9098 all phecode
802 Fracture of pelvis Injuries & Poisonings 1.01 0.902 – 1.13 0.86 321 3192 all phecode
803 Fracture of upper limb Injuries & Poisonings 1.01 0.964 – 1.07 0.578 1644 16288 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.02 0.937 – 1.11 0.654 592 5913 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.99 0.924 – 1.06 0.779 899 8929 all phecode
803.21 Colles' fracture Injuries & Poisonings 1.03 0.901 – 1.17 0.694 248 2475 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.06 0.956 – 1.17 0.279 419 4190 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 1.03 0.97 – 1.09 0.355 1272 12504 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.989 0.93 – 1.05 0.726 1082 10755 all phecode
807 Fracture of ribs Injuries & Poisonings 0.958 0.878 – 1.05 0.34 543 5428 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.986 0.946 – 1.03 0.518 2426 23282 all phecode
817 Concussion Injuries & Poisonings 0.993 0.922 – 1.07 0.856 771 7696 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.94 0.822 – 1.08 0.366 240 2380 all phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.833 0.653 – 1.06 0.14 74 740 all phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 0.888 0.705 – 1.12 0.312 84 837 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.983 0.936 – 1.03 0.503 1782 17605 all phecode
830 Dislocation Injuries & Poisonings 1.01 0.972 – 1.05 0.657 3129 28682 all phecode
835 Internal derangement of knee Injuries & Poisonings 1 0.957 – 1.06 0.854 1774 17453 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.02 0.921 – 1.12 0.743 423 4213 all phecode
840 Sprains and strains Injuries & Poisonings 0.984 0.957 – 1.01 0.24 6106 31582 all phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.943 0.854 – 1.04 0.239 429 4269 all phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.957 0.905 – 1.01 0.124 1343 13394 all phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.951 0.91 – 0.994 0.0257 2261 19530 all phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.975 0.918 – 1.04 0.41 1175 11729 all phecode
842 Other sprains and strains Injuries & Poisonings 0.979 0.919 – 1.04 0.505 1079 10729 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.993 0.947 – 1.04 0.791 1807 18037 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.99 0.919 – 1.07 0.783 797 7958 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.04 0.938 – 1.15 0.455 398 3977 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.969 0.919 – 1.02 0.24 1537 15333 all phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 0.939 0.824 – 1.07 0.341 254 2540 all phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.01 0.889 – 1.15 0.877 262 2617 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.01 0.952 – 1.07 0.729 1196 11925 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.979 0.934 – 1.03 0.388 1892 18846 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 0.94 0.895 – 0.986 0.0112 1820 18191 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1 0.829 – 1.21 0.99 127 1266 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.988 0.953 – 1.02 0.502 3389 30552 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.01 0.858 – 1.18 0.938 156 1551 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.94 0.771 – 1.15 0.545 114 1131 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.07 1.01 – 1.14 0.0339 1064 10560 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.14 0.971 – 1.34 0.11 168 1667 all phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 0.873 0.762 – 0.999 0.0488 230 2293 all phecode
870.6 Open wound of neck Injuries & Poisonings 1 0.858 – 1.17 0.988 184 1833 all phecode
870.8 Open wound of genital organs Injuries & Poisonings 0.866 0.713 – 1.05 0.147 117 1170 all phecode
871 Open wounds of extremities Injuries & Poisonings 0.971 0.933 – 1.01 0.15 2705 26585 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.929 0.841 – 1.03 0.144 438 4378 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.912 0.845 – 0.985 0.0186 731 7291 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.12 0.996 – 1.25 0.0576 331 3277 all phecode
871.4 Open wound of toe(s) Injuries & Poisonings 0.958 0.825 – 1.11 0.568 191 1901 all phecode
872 Traumatic amputation Injuries & Poisonings 1 0.906 – 1.11 0.945 415 4129 all phecode
873 Broken tooth Injuries & Poisonings 0.975 0.823 – 1.15 0.767 148 1471 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.16 0.97 – 1.4 0.102 122 1220 all phecode
875 Non-healing surgical wound Injuries & Poisonings 1 0.915 – 1.1 0.951 495 4950 all phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 0.995 0.918 – 1.08 0.893 669 6680 all phecode
907 Injuries to the nervous system Injuries & Poisonings 0.963 0.899 – 1.03 0.289 888 8852 all phecode
910 Superficial injury, infected Injuries & Poisonings 0.881 0.71 – 1.09 0.25 89 887 all phecode
911 Blister Injuries & Poisonings 1.03 0.888 – 1.21 0.666 185 1838 all phecode
912 Insect bite Injuries & Poisonings 0.972 0.866 – 1.09 0.628 321 3207 all phecode
913 Toxic effect of venom Injuries & Poisonings 1.05 0.918 – 1.19 0.495 247 2461 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 0.979 0.938 – 1.02 0.316 2368 23457 all phecode
916 Contusion Injuries & Poisonings 0.998 0.962 – 1.03 0.896 3199 30228 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.982 0.902 – 1.07 0.681 597 5953 all phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Injuries & Poisonings 0.999 0.912 – 1.09 0.98 530 5290 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.12 1.08 – 1.15 6.54e-11 4197 24407 all phecode
938.1 Acute dermatitis due to solar radiation Injuries & Poisonings 1.2 1.03 – 1.4 0.021 164 1640 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 1.12 1.08 – 1.16 2.74e-11 4001 24007 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.999 0.969 – 1.03 0.956 5120 27320 all phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 0.814 0.63 – 1.05 0.116 64 626 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.04 0.878 – 1.24 0.626 140 1400 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.977 0.854 – 1.12 0.74 221 2205 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.05 0.949 – 1.17 0.325 385 3830 all phecode
947 Urticaria Injuries & Poisonings 1 0.935 – 1.08 0.938 889 8845 all phecode
949 Allergies, other Injuries & Poisonings 0.973 0.944 – 1 0.0792 5269 26807 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.919 0.831 – 1.02 0.104 419 4176 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.02 0.847 – 1.23 0.818 116 1150 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.01 0.945 – 1.07 0.854 1073 10721 all phecode
958.1 Postoperative shock Injuries & Poisonings 0.959 0.807 – 1.14 0.634 133 1325 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.935 0.758 – 1.15 0.528 92 911 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.986 0.943 – 1.03 0.547 2108 18753 all phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 0.956 0.812 – 1.12 0.585 158 1552 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.995 0.941 – 1.05 0.845 1414 13864 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 0.967 0.88 – 1.06 0.482 470 4694 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.961 0.898 – 1.03 0.256 939 9190 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.93 0.853 – 1.02 0.105 561 5601 all phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 0.935 0.832 – 1.05 0.263 308 3069 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 0.895 0.796 – 1.01 0.0633 305 3029 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.974 0.931 – 1.02 0.269 2031 19919 all phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 0.98 0.935 – 1.03 0.388 1980 19507 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.01 0.924 – 1.11 0.796 538 5360 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.03 0.936 – 1.13 0.569 509 5070 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.981 0.91 – 1.06 0.62 753 7525 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.958 0.905 – 1.01 0.143 1305 12848 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.831 0.67 – 1.03 0.0929 98 967 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.905 0.724 – 1.13 0.378 86 850 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.972 0.91 – 1.04 0.392 1000 9986 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 0.956 0.834 – 1.1 0.518 234 2331 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.977 0.743 – 1.29 0.87 56 546 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.06 0.925 – 1.21 0.405 228 2269 all phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 1.01 0.772 – 1.31 0.97 66 637 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.11 0.901 – 1.37 0.327 86 860 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.982 0.793 – 1.22 0.868 90 896 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.921 0.721 – 1.18 0.513 69 686 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.07 0.831 – 1.37 0.611 60 600 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.97 0.921 – 1.02 0.26 1565 14843 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 0.979 0.936 – 1.02 0.347 2116 20636 all phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 0.958 0.902 – 1.02 0.159 1166 11657 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.851 0.681 – 1.07 0.159 91 904 all phecode
990 Effects radiation NOS Injuries & Poisonings 0.961 0.923 – 1 0.0476 2707 23906 all phecode
994 Sepsis and SIRS Injuries & Poisonings 0.945 0.899 – 0.994 0.0273 1724 17160 all phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 0.875 0.767 – 0.999 0.0479 248 2472 all phecode
994.2 Sepsis Injuries & Poisonings 0.955 0.907 – 1 0.0766 1636 16281 all phecode
994.21 Septic shock Injuries & Poisonings 0.908 0.826 – 0.997 0.0421 484 4840 all phecode
008 Intestinal infection Infectious Diseases 0.985 0.939 – 1.03 0.547 1815 18901 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.05 0.981 – 1.13 0.15 834 8637 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.06 0.978 – 1.14 0.163 685 7065 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 0.876 0.797 – 0.963 0.00625 469 4968 exclusion phecode
010 Tuberculosis Infectious Diseases 0.9 0.763 – 1.06 0.213 157 1511 exclusion phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.83 0.632 – 1.09 0.177 51 586 exclusion phecode
038 Septicemia Infectious Diseases 0.955 0.906 – 1.01 0.0875 1566 15677 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 0.994 0.89 – 1.11 0.91 342 3475 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 0.878 0.743 – 1.04 0.129 149 1447 exclusion phecode
038.3 Bacteremia Infectious Diseases 0.96 0.889 – 1.04 0.298 724 7308 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 0.98 0.946 – 1.01 0.243 3697 26368 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 0.963 0.905 – 1.03 0.241 1110 11149 exclusion phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 0.925 0.848 – 1.01 0.0814 569 5749 exclusion phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.01 0.922 – 1.11 0.829 516 5228 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 0.995 0.933 – 1.06 0.891 1021 10247 exclusion phecode
041.21 Rheumatic fever / chorea Infectious Diseases 1.01 0.859 – 1.2 0.875 161 1558 exclusion phecode
041.4 E. coli Infectious Diseases 1.01 0.933 – 1.08 0.89 766 7406 exclusion phecode
041.8 H. pylori Infectious Diseases 0.954 0.807 – 1.13 0.577 153 1509 exclusion phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.01 0.87 – 1.18 0.873 182 1786 exclusion phecode
053 Herpes zoster Infectious Diseases 0.957 0.893 – 1.03 0.217 882 9403 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.905 0.749 – 1.09 0.296 124 1288 exclusion phecode
054 Herpes simplex Infectious Diseases 0.957 0.896 – 1.02 0.19 972 10461 exclusion phecode
070 Viral hepatitis Infectious Diseases 0.982 0.898 – 1.07 0.683 523 5344 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 0.907 0.682 – 1.2 0.499 52 507 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.9 0.75 – 1.08 0.255 122 1309 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.01 0.903 – 1.12 0.904 358 3534 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 0.958 0.792 – 1.16 0.655 117 1299 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 0.94 0.869 – 1.02 0.118 682 7405 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.09 0.886 – 1.35 0.403 98 1031 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.05 0.821 – 1.33 0.715 74 794 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.955 0.912 – 1 0.0537 2007 20521 exclusion phecode
079 Viral infection Infectious Diseases 0.968 0.934 – 1 0.0759 3479 24660 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.987 0.938 – 1.04 0.604 1666 21269 exclusion phecode
079.2 Infectious mononucleosis Infectious Diseases 0.948 0.811 – 1.11 0.505 181 1918 exclusion phecode
079.9 Viremia, NOS Infectious Diseases 0.967 0.879 – 1.06 0.495 464 4904 exclusion phecode
080 Postoperative infection Infectious Diseases 0.989 0.944 – 1.04 0.65 1943 20770 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 0.938 0.882 – 0.999 0.0462 1113 10951 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.963 0.884 – 1.05 0.39 573 6025 exclusion phecode
1000 Burns Injuries & Poisonings 0.941 0.86 – 1.03 0.182 534 5328 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 0.988 0.941 – 1.04 0.625 1820 17941 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 0.998 0.964 – 1.03 0.925 3654 26714 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.02 0.956 – 1.09 0.524 967 9460 exclusion phecode
1005 Other symptoms Injuries & Poisonings 0.992 0.965 – 1.02 0.593 6131 25122 exclusion phecode
1006 Crushing injury Injuries & Poisonings 0.994 0.863 – 1.15 0.937 218 2053 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 1.07 0.957 – 1.2 0.233 343 3250 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 0.922 0.854 – 0.995 0.0371 742 7515 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 0.98 0.954 – 1.01 0.12 7593 23656 exclusion phecode
1010 Other tests Injuries & Poisonings 0.971 0.95 – 0.993 0.0113 15255 16004 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.966 0.936 – 0.997 0.0331 4540 26628 exclusion phecode
1012 Late effect Injuries & Poisonings 0.957 0.881 – 1.04 0.305 611 6329 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 0.974 0.928 – 1.02 0.272 1890 18334 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.09 0.916 – 1.29 0.335 141 1442 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 1.01 0.979 – 1.04 0.505 4415 26828 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.02 0.969 – 1.07 0.465 1698 16760 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.99 0.942 – 1.04 0.679 1763 18755 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.986 0.937 – 1.04 0.603 1590 16873 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.972 0.907 – 1.04 0.407 921 9723 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.02 0.92 – 1.12 0.746 412 4592 exclusion phecode
110.13 Dermatophytosis of the body Infectious Diseases 0.951 0.861 – 1.05 0.325 420 4611 exclusion phecode
110.2 Dermatomycoses Infectious Diseases 0.967 0.841 – 1.11 0.635 223 2384 exclusion phecode
1100 Family history Injuries & Poisonings 0.985 0.845 – 1.15 0.847 179 1867 exclusion phecode
112 Candidiasis Infectious Diseases 1.02 0.972 – 1.06 0.496 2270 20836 exclusion phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.01 0.913 – 1.12 0.849 409 4371 exclusion phecode
117 Mycoses Infectious Diseases 0.965 0.867 – 1.07 0.505 401 4033 exclusion phecode
117.1 Histoplasmosis Infectious Diseases 1.07 0.818 – 1.4 0.615 56 518 exclusion phecode
117.4 Aspergillosis Infectious Diseases 0.924 0.733 – 1.16 0.503 80 855 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.86 0.696 – 1.06 0.161 94 976 exclusion phecode
130.1 Lyme disease Infectious Diseases 0.842 0.655 – 1.08 0.181 66 712 exclusion phecode
132 Infestation (lice, mites) Infectious Diseases 0.907 0.75 – 1.1 0.31 121 1262 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.952 0.907 – 1 0.0478 1825 19785 exclusion phecode
145 Cancer of mouth Neoplasms 0.979 0.896 – 1.07 0.636 505 9121 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.01 0.891 – 1.15 0.83 240 4313 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 1.02 0.864 – 1.2 0.812 144 2347 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 0.877 0.679 – 1.13 0.317 57 1378 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.985 0.905 – 1.07 0.727 562 8749 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 0.934 0.787 – 1.11 0.44 134 2281 exclusion phecode
149.2 Cancer of nasopharynx Neoplasms 0.788 0.6 – 1.03 0.0862 53 693 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.01 0.878 – 1.16 0.893 205 2602 exclusion phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 0.947 0.823 – 1.09 0.447 202 3909 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.1 0.891 – 1.37 0.365 87 1591 exclusion phecode
150 Cancer of esophagus Neoplasms 0.91 0.806 – 1.03 0.128 294 2905 exclusion phecode
151 Cancer of stomach Neoplasms 0.906 0.809 – 1.02 0.0916 345 3289 exclusion phecode
153 Colorectal cancer Neoplasms 1.04 0.969 – 1.12 0.274 837 9151 exclusion phecode
153.2 Colon cancer Neoplasms 1.03 0.948 – 1.11 0.531 681 7130 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.03 0.937 – 1.13 0.532 461 5204 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.981 0.872 – 1.1 0.742 313 3287 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.02 0.882 – 1.17 0.829 210 2230 exclusion phecode
157 Pancreatic cancer Neoplasms 1.03 0.918 – 1.14 0.66 344 3285 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1 0.939 – 1.07 0.923 969 10494 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.08 0.994 – 1.17 0.0705 591 6151 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.914 0.764 – 1.09 0.324 140 1431 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.13 0.923 – 1.38 0.237 103 1014 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.11 0.961 – 1.28 0.155 200 2062 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.836 0.65 – 1.07 0.162 65 860 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.02 0.943 – 1.11 0.576 633 7043 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.01 0.926 – 1.1 0.838 583 6485 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 0.971 0.902 – 1.04 0.427 755 11950 exclusion phecode
170.1 Bone cancer Neoplasms 0.925 0.828 – 1.03 0.166 339 5247 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 0.984 0.902 – 1.07 0.712 540 8540 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.98 0.907 – 1.06 0.604 675 15093 exclusion phecode
174 Breast cancer Neoplasms 0.964 0.92 – 1.01 0.127 2085 11032 exclusion phecode
174.1 Breast cancer [female] Neoplasms 0.967 0.922 – 1.01 0.169 2024 10602 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.972 0.926 – 1.02 0.248 1997 10564 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.93 0.794 – 1.09 0.371 162 1659 exclusion phecode
175 Acquired absence of breast Neoplasms 0.938 0.873 – 1.01 0.0826 810 7758 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 0.967 0.905 – 1.03 0.321 1007 9073 exclusion phecode
180.1 Cervical cancer Neoplasms 0.988 0.885 – 1.1 0.822 358 3664 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.966 0.894 – 1.04 0.374 745 6960 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.969 0.887 – 1.06 0.488 530 5105 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.02 0.94 – 1.1 0.692 694 7347 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.07 0.963 – 1.18 0.217 392 3961 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.06 0.947 – 1.19 0.304 310 3000 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.938 0.845 – 1.04 0.234 372 4284 exclusion phecode
185 Cancer of prostate Neoplasms 0.949 0.898 – 1 0.0623 1792 6683 exclusion phecode
187 Cancer of other male genital organs Neoplasms 0.946 0.814 – 1.1 0.474 194 2129 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.821 0.609 – 1.11 0.198 52 674 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 1.15 0.951 – 1.4 0.149 116 1171 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.01 0.963 – 1.06 0.691 1995 15631 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.01 0.942 – 1.07 0.862 992 9368 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.989 0.922 – 1.06 0.767 857 8058 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.05 0.883 – 1.24 0.604 159 1396 exclusion phecode
189.2 Cancer of bladder Neoplasms 1 0.942 – 1.06 0.994 1233 9865 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.01 0.945 – 1.07 0.864 1143 9102 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.984 0.894 – 1.08 0.746 468 4028 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.954 0.882 – 1.03 0.233 682 7416 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.977 0.887 – 1.08 0.632 439 4747 exclusion phecode
191.11 Cancer of brain Neoplasms 0.985 0.889 – 1.09 0.778 386 3977 exclusion phecode
193 Thyroid cancer Neoplasms 0.952 0.879 – 1.03 0.229 646 6603 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 0.968 0.833 – 1.12 0.669 180 1762 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.02 0.992 – 1.05 0.175 7457 21288 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.02 0.994 – 1.05 0.123 7136 21246 exclusion phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1 0.9 – 1.11 0.978 354 7894 exclusion phecode
196 Radiotherapy Neoplasms 0.999 0.943 – 1.06 0.967 1289 14004 exclusion phecode
197 Chemotherapy Neoplasms 1.01 0.968 – 1.05 0.711 2828 19391 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 0.99 0.951 – 1.03 0.615 2916 19646 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1 0.955 – 1.06 0.848 1632 18056 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.95 0.87 – 1.04 0.258 538 7899 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.986 0.903 – 1.08 0.753 537 6355 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 0.99 0.898 – 1.09 0.843 443 5704 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.979 0.868 – 1.1 0.731 279 4841 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 0.953 0.863 – 1.05 0.342 418 6143 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1 0.968 – 1.04 0.837 3547 20973 exclusion phecode
199.4 Neurofibromatosis Neoplasms 0.92 0.698 – 1.21 0.555 57 686 exclusion phecode
200 Myeloproliferative disease Neoplasms 0.956 0.881 – 1.04 0.287 644 6971 exclusion phecode
200.1 Polycythemia vera Neoplasms 0.894 0.741 – 1.08 0.243 118 1279 exclusion phecode
201 Hodgkin's disease Neoplasms 1.14 0.932 – 1.4 0.201 96 1116 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.968 0.901 – 1.04 0.363 835 10137 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.965 0.894 – 1.04 0.362 715 8843 exclusion phecode
202.21 Nodular lymphoma Neoplasms 0.958 0.865 – 1.06 0.405 401 4920 exclusion phecode
202.22 Reticulosarcoma Neoplasms 0.952 0.779 – 1.16 0.631 97 1041 exclusion phecode
202.24 Large cell lymphoma Neoplasms 0.96 0.782 – 1.18 0.699 97 1004 exclusion phecode
204 Leukemia Neoplasms 1.02 0.915 – 1.14 0.714 345 4094 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 0.951 0.784 – 1.15 0.611 109 1428 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.03 0.817 – 1.31 0.779 74 987 exclusion phecode
204.2 Myeloid leukemia Neoplasms 0.958 0.806 – 1.14 0.631 135 1567 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.855 0.684 – 1.07 0.169 86 962 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.17 0.966 – 1.42 0.108 113 1308 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1 0.972 – 1.03 0.995 6220 24252 exclusion phecode
209 Neuroendocrine tumors Neoplasms 1.13 0.973 – 1.32 0.107 181 1741 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.972 0.912 – 1.04 0.375 1040 13056 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.997 0.966 – 1.03 0.856 4780 24812 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.01 0.953 – 1.07 0.711 1196 12399 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.964 0.907 – 1.02 0.239 1132 12096 exclusion phecode
214 Lipoma Neoplasms 0.983 0.917 – 1.05 0.623 887 9070 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.01 0.928 – 1.11 0.759 533 5588 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.993 0.954 – 1.03 0.735 2677 26935 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.977 0.948 – 1.01 0.125 5218 25835 exclusion phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 0.968 0.781 – 1.2 0.764 77 987 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.01 0.926 – 1.1 0.852 561 9864 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.975 0.89 – 1.07 0.58 487 9079 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.997 0.958 – 1.04 0.881 3075 11718 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.981 0.926 – 1.04 0.527 1271 11368 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.994 0.952 – 1.04 0.803 2482 11626 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.979 0.904 – 1.06 0.591 674 6479 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.06 1 – 1.12 0.0455 1425 10302 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.89 0.824 – 0.961 0.00309 750 6653 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.03 0.974 – 1.1 0.275 1280 9878 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.985 0.883 – 1.1 0.789 348 3796 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.961 0.852 – 1.08 0.521 293 3135 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1 0.934 – 1.08 0.918 842 8435 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.01 0.935 – 1.1 0.759 682 6629 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.941 0.805 – 1.1 0.444 175 1959 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.908 0.848 – 0.973 0.00641 894 8855 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.998 0.94 – 1.06 0.96 1179 11200 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.978 0.871 – 1.1 0.713 309 2971 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.996 0.913 – 1.09 0.933 549 5223 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.15 1.03 – 1.29 0.0158 328 3037 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.952 0.889 – 1.02 0.16 875 12046 exclusion phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.965 0.874 – 1.07 0.484 405 6575 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.977 0.946 – 1.01 0.168 4363 26409 exclusion phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.967 0.931 – 1 0.0877 2989 24929 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.943 0.869 – 1.02 0.156 629 6240 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.951 0.906 – 0.999 0.0477 1804 14911 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.954 0.903 – 1.01 0.0993 1411 13369 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.904 0.841 – 0.971 0.00596 816 8184 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.01 0.938 – 1.08 0.873 876 8639 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.988 0.885 – 1.1 0.832 342 3308 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 0.873 0.7 – 1.09 0.227 84 793 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.867 0.748 – 1.01 0.0601 204 2022 exclusion phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.847 0.686 – 1.05 0.121 102 984 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 0.94 0.911 – 0.97 0.000113 5114 22093 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.951 0.894 – 1.01 0.105 1126 11592 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.941 0.867 – 1.02 0.143 641 6889 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.939 0.909 – 0.97 0.000153 4743 21668 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.947 0.861 – 1.04 0.255 481 4814 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.937 0.844 – 1.04 0.22 404 3934 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.934 0.841 – 1.04 0.204 398 3854 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 0.929 0.897 – 0.962 3.72e-05 3949 20311 exclusion phecode
246.2 Thyroid cyst Endocrine/metabolic 0.924 0.718 – 1.19 0.536 63 637 exclusion phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 0.955 0.863 – 1.06 0.374 417 4574 exclusion phecode
249 Secondary diabetes mellitus Endocrine/metabolic 0.92 0.838 – 1.01 0.0833 500 5274 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 0.949 0.924 – 0.974 0.000108 7843 22755 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.881 0.819 – 0.948 0.000698 820 8305 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.819 0.627 – 1.07 0.141 63 662 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.924 0.789 – 1.08 0.325 175 1895 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.943 0.821 – 1.08 0.403 219 2295 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 0.942 0.807 – 1.1 0.45 182 1924 exclusion phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 1.17 0.87 – 1.57 0.301 54 541 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.945 0.917 – 0.975 0.000315 5474 21392 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.732 0.588 – 0.912 0.0053 93 952 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.978 0.91 – 1.05 0.538 835 8283 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.996 0.917 – 1.08 0.926 622 6256 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 0.956 0.898 – 1.02 0.157 1099 10681 exclusion phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 0.945 0.848 – 1.05 0.3 385 3689 exclusion phecode
250.3 Insulin pump user Endocrine/metabolic 0.964 0.913 – 1.02 0.189 1464 13972 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 0.948 0.916 – 0.981 0.002 4144 21669 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.934 0.874 – 0.997 0.0398 1007 10219 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.948 0.914 – 0.982 0.0033 3621 21128 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.04 0.812 – 1.33 0.756 69 626 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.954 0.889 – 1.02 0.194 870 8651 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.996 0.917 – 1.08 0.915 624 6327 exclusion phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 0.911 0.828 – 1 0.0568 464 4772 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 0.92 0.843 – 1 0.0605 551 5676 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.02 0.963 – 1.07 0.569 1458 14368 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.01 0.957 – 1.07 0.664 1332 13173 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.937 0.837 – 1.05 0.261 329 3220 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.03 0.941 – 1.12 0.56 561 5626 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.964 0.827 – 1.12 0.643 186 1723 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.19 0.93 – 1.53 0.166 67 605 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.15 0.976 – 1.36 0.0948 149 1473 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.872 0.666 – 1.14 0.317 62 561 exclusion phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 1.04 0.814 – 1.32 0.778 67 743 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.24 0.944 – 1.64 0.121 60 694 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.942 0.881 – 1.01 0.0822 924 9508 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.05 0.929 – 1.19 0.418 241 2374 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.12 0.932 – 1.34 0.231 121 1219 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.1 0.889 – 1.36 0.383 87 835 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.933 0.837 – 1.04 0.207 370 3921 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.926 0.829 – 1.03 0.175 351 3699 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.925 0.86 – 0.996 0.038 792 7313 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.948 0.866 – 1.04 0.254 519 4974 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 0.986 0.904 – 1.08 0.752 557 5777 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.985 0.902 – 1.08 0.735 537 5576 exclusion phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.827 0.654 – 1.05 0.114 82 817 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.992 0.914 – 1.08 0.845 622 6228 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.02 0.969 – 1.07 0.477 1732 17549 exclusion phecode
260.1 Cachexia Endocrine/metabolic 0.828 0.708 – 0.969 0.0188 174 1844 exclusion phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.01 0.948 – 1.08 0.738 1014 10584 exclusion phecode
260.22 Nutritional marasmus Endocrine/metabolic 0.951 0.843 – 1.07 0.409 295 3255 exclusion phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.04 0.93 – 1.15 0.519 380 3815 exclusion phecode
260.6 Anorexia Endocrine/metabolic 0.905 0.824 – 0.993 0.0355 494 5153 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 0.967 0.936 – 0.998 0.0372 4597 24696 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.923 0.841 – 1.01 0.0869 507 5120 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.966 0.935 – 0.998 0.0375 4337 24501 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.934 0.863 – 1.01 0.0921 683 6970 exclusion phecode
263 Other nutritional deficiency Endocrine/metabolic 0.962 0.857 – 1.08 0.504 325 3286 exclusion phecode
264 Lack of normal physiological development Endocrine/metabolic 1.07 0.908 – 1.26 0.421 151 1491 exclusion phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.02 0.8 – 1.29 0.89 77 771 exclusion phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 0.87 0.664 – 1.14 0.313 57 563 exclusion phecode
269 Proteinuria Endocrine/metabolic 0.977 0.91 – 1.05 0.529 821 8528 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.962 0.881 – 1.05 0.394 552 5667 exclusion phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.847 0.696 – 1.03 0.0955 111 1069 exclusion phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.843 0.676 – 1.05 0.128 88 838 exclusion phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 0.946 0.741 – 1.21 0.655 70 664 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.996 0.898 – 1.1 0.935 398 4208 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 0.94 0.81 – 1.09 0.414 193 2144 exclusion phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.06 0.898 – 1.25 0.495 167 1714 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.955 0.906 – 1.01 0.0894 1536 15437 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.957 0.907 – 1.01 0.113 1481 14895 exclusion phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.939 0.723 – 1.22 0.634 66 687 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.971 0.946 – 0.996 0.0225 11422 18982 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.971 0.947 – 0.996 0.0247 11401 18967 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.97 0.933 – 1.01 0.129 3391 15109 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.866 0.802 – 0.935 0.000237 758 7327 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.934 0.887 – 0.984 0.01 1710 12235 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.905 0.771 – 1.06 0.225 164 1825 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.04 0.986 – 1.1 0.148 1460 13861 exclusion phecode
274.1 Gout Endocrine/metabolic 1.04 0.981 – 1.1 0.205 1397 13373 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.04 0.953 – 1.13 0.39 589 5957 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.16 0.951 – 1.42 0.141 105 1037 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.16 0.943 – 1.43 0.16 99 988 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.999 0.959 – 1.04 0.977 2546 24255 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 1.03 0.857 – 1.23 0.776 127 1334 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 0.955 0.881 – 1.04 0.27 648 6651 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.02 0.975 – 1.07 0.37 1973 19758 exclusion phecode
275.51 Hypocalcemia Endocrine/metabolic 0.988 0.907 – 1.08 0.79 581 5867 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.01 0.941 – 1.09 0.756 813 8066 exclusion phecode
275.6 Hypercalcemia Endocrine/metabolic 0.996 0.927 – 1.07 0.907 806 8255 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 0.988 0.959 – 1.02 0.415 5464 25573 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 0.983 0.949 – 1.02 0.341 3630 23410 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.01 0.896 – 1.13 0.926 326 3190 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 0.983 0.929 – 1.04 0.558 1337 13918 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 0.991 0.942 – 1.04 0.726 1656 16127 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 0.978 0.923 – 1.04 0.46 1253 12850 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.994 0.937 – 1.05 0.843 1228 12504 exclusion phecode
276.41 Acidosis Endocrine/metabolic 0.975 0.914 – 1.04 0.428 1059 10725 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 0.982 0.865 – 1.12 0.785 256 2757 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 0.991 0.952 – 1.03 0.652 2667 23703 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1 0.929 – 1.08 0.996 795 7928 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 0.919 0.735 – 1.15 0.454 84 838 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 0.912 0.858 – 0.968 0.00256 1198 12317 exclusion phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 0.971 0.838 – 1.13 0.697 186 1933 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1 0.905 – 1.11 0.975 417 4349 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.928 0.849 – 1.01 0.0988 548 5461 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.915 0.83 – 1.01 0.0719 455 4557 exclusion phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 0.956 0.872 – 1.05 0.332 509 4980 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.988 0.966 – 1.01 0.314 12525 18704 exclusion phecode
278.1 Obesity Endocrine/metabolic 0.987 0.964 – 1.01 0.29 11233 18708 exclusion phecode
278.11 Morbid obesity Endocrine/metabolic 0.982 0.953 – 1.01 0.25 5435 18665 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 0.847 0.74 – 0.97 0.0163 236 2203 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.973 0.918 – 1.03 0.356 1287 11387 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.969 0.922 – 1.02 0.22 1712 18411 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1 0.927 – 1.09 0.915 661 7202 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.951 0.818 – 1.11 0.513 189 2051 exclusion phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 0.908 0.825 – 1 0.0517 458 4750 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 0.975 0.939 – 1.01 0.191 3074 24955 exclusion phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 0.954 0.855 – 1.06 0.396 353 3706 exclusion phecode
280 Iron deficiency anemias Hematopoietic 0.99 0.951 – 1.03 0.614 2777 20815 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.984 0.945 – 1.03 0.451 2675 20591 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.01 0.945 – 1.07 0.833 1059 10690 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.08 0.954 – 1.22 0.228 282 2929 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.07 0.898 – 1.27 0.466 139 1442 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1 0.786 – 1.29 0.969 69 647 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.02 0.836 – 1.25 0.831 104 1025 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.09 0.925 – 1.29 0.3 156 1597 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 0.845 0.725 – 0.985 0.0315 188 1949 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 0.848 0.699 – 1.03 0.0973 120 1241 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.826 0.67 – 1.02 0.0719 101 1101 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 0.987 0.797 – 1.22 0.905 93 1005 exclusion phecode
284 Aplastic anemia Hematopoietic 0.934 0.842 – 1.04 0.193 409 4352 exclusion phecode
284.1 Pancytopenia Hematopoietic 0.957 0.857 – 1.07 0.438 358 3820 exclusion phecode
285 Other anemias Hematopoietic 0.987 0.961 – 1.01 0.321 7429 23080 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.984 0.938 – 1.03 0.49 1954 17925 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 0.989 0.931 – 1.05 0.709 1181 12413 exclusion phecode
285.21 Anemia in chronic kidney disease Hematopoietic 0.978 0.892 – 1.07 0.637 496 5258 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.02 0.92 – 1.12 0.752 412 4369 exclusion phecode
286 Coagulation defects Hematopoietic 0.988 0.947 – 1.03 0.584 2362 21819 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.94 0.8 – 1.11 0.453 160 1584 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.917 0.691 – 1.22 0.549 53 540 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.884 0.708 – 1.1 0.277 84 814 exclusion phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 0.992 0.945 – 1.04 0.727 1920 16320 exclusion phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 1.12 0.847 – 1.47 0.433 58 534 exclusion phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 0.87 0.732 – 1.03 0.115 145 1451 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.28 1 – 1.63 0.0463 73 708 exclusion phecode
286.6 Defibrination syndrome Hematopoietic 0.985 0.934 – 1.04 0.564 1560 15485 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.988 0.941 – 1.04 0.609 1856 18457 exclusion phecode
286.8 Hypercoagulable state Hematopoietic 1 0.918 – 1.1 0.922 533 5298 exclusion phecode
286.81 Primary hypercoagulable state Hematopoietic 0.988 0.901 – 1.08 0.799 510 5099 exclusion phecode
286.9 Abnormal coagulation profile Hematopoietic 0.991 0.914 – 1.07 0.835 667 6639 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.991 0.945 – 1.04 0.712 1923 17950 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.824 0.679 – 1 0.0509 117 1237 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 0.996 0.948 – 1.05 0.885 1754 16472 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.01 0.906 – 1.12 0.872 377 3711 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.917 0.818 – 1.03 0.131 338 3439 exclusion phecode
288 Diseases of white blood cells Hematopoietic 0.987 0.95 – 1.03 0.511 2995 25111 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.02 0.957 – 1.09 0.502 932 10238 exclusion phecode
288.11 Neutropenia Hematopoietic 1.02 0.943 – 1.11 0.601 664 7298 exclusion phecode
288.2 Elevated white blood cell count Hematopoietic 0.981 0.941 – 1.02 0.364 2491 23474 exclusion phecode
288.3 Eosinophilia Hematopoietic 0.969 0.791 – 1.19 0.762 107 1062 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.946 0.886 – 1.01 0.102 993 10122 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.932 0.85 – 1.02 0.13 509 5093 exclusion phecode
289.4 Lymphadenitis Hematopoietic 0.982 0.94 – 1.03 0.42 2209 23367 exclusion phecode
289.5 Diseases of spleen Hematopoietic 0.864 0.755 – 0.988 0.0329 239 2526 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 0.88 0.74 – 1.05 0.149 144 1456 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.05 0.912 – 1.22 0.475 207 2170 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.946 0.876 – 1.02 0.158 719 6834 exclusion phecode
290.1 Dementias Mental Disorders 0.866 0.764 – 0.982 0.025 265 2553 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.766 0.6 – 0.977 0.0317 71 628 exclusion phecode
290.13 Senile dementia Mental Disorders 0.891 0.76 – 1.05 0.158 161 1563 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.988 0.897 – 1.09 0.798 447 4632 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.976 0.889 – 1.07 0.607 479 4879 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.928 0.881 – 0.978 0.00502 1580 15923 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.955 0.8 – 1.14 0.611 133 1440 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.941 0.836 – 1.06 0.31 296 2980 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 0.924 0.871 – 0.981 0.00914 1234 12367 exclusion phecode
292 Neurological disorders Mental Disorders 0.97 0.935 – 1.01 0.104 3276 25920 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.913 0.859 – 0.972 0.00416 1128 12159 exclusion phecode
292.11 Aphasia Mental Disorders 0.873 0.789 – 0.967 0.00919 407 4037 exclusion phecode
292.12 Symbolic dysfunction Mental Disorders 0.855 0.716 – 1.02 0.0839 128 1311 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.864 0.743 – 1 0.0576 188 1902 exclusion phecode
292.3 Memory loss Mental Disorders 0.974 0.913 – 1.04 0.42 1037 10514 exclusion phecode
292.4 Altered mental status Mental Disorders 0.939 0.888 – 0.992 0.026 1390 13958 exclusion phecode
292.5 Transient alteration of awareness Mental Disorders 0.872 0.768 – 0.991 0.0359 263 2554 exclusion phecode
292.6 Hallucinations Mental Disorders 1.02 0.841 – 1.24 0.836 109 1130 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 0.998 0.872 – 1.14 0.982 233 2518 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.986 0.947 – 1.03 0.501 2646 26528 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.96 0.874 – 1.05 0.395 494 5330 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.03 0.836 – 1.27 0.766 94 944 exclusion phecode
295.2 Paranoid disorders Mental Disorders 0.88 0.686 – 1.13 0.312 70 728 exclusion phecode
295.3 Psychosis Mental Disorders 0.988 0.888 – 1.1 0.83 383 4183 exclusion phecode
296 Mood disorders Mental Disorders 0.991 0.966 – 1.02 0.499 9976 15220 exclusion phecode
296.1 Bipolar Mental Disorders 1.05 0.975 – 1.12 0.211 872 8271 exclusion phecode
296.2 Depression Mental Disorders 0.989 0.964 – 1.02 0.422 9640 15217 exclusion phecode
296.22 Major depressive disorder Mental Disorders 0.993 0.967 – 1.02 0.607 8917 15218 exclusion phecode
297 Suicidal ideation or attempt Mental Disorders 1 0.923 – 1.09 0.922 616 6115 exclusion phecode
297.1 Suicidal ideation Mental Disorders 1.03 0.939 – 1.13 0.532 499 4933 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.02 0.878 – 1.2 0.757 182 1804 exclusion phecode
300 Anxiety disorders Mental Disorders 0.982 0.957 – 1.01 0.176 9841 15220 exclusion phecode
300.1 Anxiety disorder Mental Disorders 0.984 0.959 – 1.01 0.238 9278 15215 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 0.993 0.957 – 1.03 0.712 3691 15081 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.958 0.891 – 1.03 0.236 845 8054 exclusion phecode
300.13 Phobia Mental Disorders 0.992 0.911 – 1.08 0.854 588 6231 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.975 0.839 – 1.13 0.743 189 1981 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 0.957 0.906 – 1.01 0.114 1461 11676 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 0.877 0.778 – 0.989 0.0327 296 3085 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.955 0.874 – 1.04 0.308 543 5439 exclusion phecode
301 Personality disorders Mental Disorders 1.05 0.932 – 1.18 0.44 320 3254 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.07 0.915 – 1.25 0.408 173 1694 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 0.952 0.867 – 1.05 0.301 499 4982 exclusion phecode
302.1 Decreased libido Mental Disorders 0.92 0.812 – 1.04 0.194 264 2725 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.01 0.938 – 1.08 0.853 866 8529 exclusion phecode
303.1 Dissociative disorder Mental Disorders 0.995 0.806 – 1.23 0.962 94 991 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 1 0.921 – 1.09 0.995 614 6194 exclusion phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 1.01 0.89 – 1.14 0.908 277 2901 exclusion phecode
303.4 Somatoform disorder Mental Disorders 1.03 0.957 – 1.11 0.429 788 7992 exclusion phecode
304 Adjustment reaction Mental Disorders 0.966 0.924 – 1.01 0.123 2332 14758 exclusion phecode
305.2 Eating disorder Mental Disorders 0.987 0.906 – 1.08 0.771 574 5772 exclusion phecode
306 Other mental disorder Mental Disorders 0.98 0.919 – 1.04 0.527 1039 9472 exclusion phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 0.922 0.83 – 1.02 0.133 398 2662 exclusion phecode
306.9 Tension headache Mental Disorders 0.939 0.852 – 1.04 0.208 445 4613 exclusion phecode
312 Conduct disorders Mental Disorders 0.894 0.764 – 1.05 0.163 159 1593 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.986 0.925 – 1.05 0.665 1036 9852 exclusion phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1.01 0.944 – 1.08 0.757 923 8870 exclusion phecode
315 Develomental delays and disorders Mental Disorders 0.967 0.864 – 1.08 0.563 325 3263 exclusion phecode
315.1 Learning disorder Mental Disorders 1.08 0.826 – 1.42 0.568 55 529 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.91 0.767 – 1.08 0.276 137 1443 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.01 0.968 – 1.06 0.629 2343 21262 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.02 0.921 – 1.13 0.728 412 4153 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1 0.95 – 1.05 0.982 1603 14080 exclusion phecode
317.1 Alcoholism Mental Disorders 0.999 0.941 – 1.06 0.972 1235 11829 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.08 0.951 – 1.22 0.245 269 2588 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.04 1.01 – 1.06 0.011 7633 21981 exclusion phecode
320 Meningitis Neurological 1.01 0.879 – 1.15 0.924 236 2634 exclusion phecode
323 Encephalitis Neurological 0.903 0.743 – 1.1 0.306 120 1230 exclusion phecode
323.8 Encephalitis, non-infectious Neurological 0.88 0.707 – 1.09 0.25 102 1035 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.07 0.925 – 1.24 0.355 186 1869 exclusion phecode
327 Sleep disorders Neurological 0.981 0.957 – 1.01 0.127 9268 21836 exclusion phecode
327.1 Hypersomnia Neurological 0.972 0.915 – 1.03 0.356 1167 11357 exclusion phecode
327.3 Sleep apnea Neurological 0.977 0.95 – 1 0.0979 6682 21384 exclusion phecode
327.31 Central/nonobstroctive sleep apnea Neurological 0.992 0.873 – 1.13 0.908 255 2479 exclusion phecode
327.32 Obstructive sleep apnea Neurological 0.976 0.947 – 1.01 0.12 5312 20746 exclusion phecode
327.4 Insomnia Neurological 0.984 0.949 – 1.02 0.401 3336 21063 exclusion phecode
327.41 Organic or persistent insomnia Neurological 0.948 0.877 – 1.02 0.177 693 7012 exclusion phecode
327.5 Parasomnia Neurological 0.952 0.854 – 1.06 0.376 363 3551 exclusion phecode
327.6 Circadian rhythm sleep disorder Neurological 1.01 0.855 – 1.19 0.916 143 1463 exclusion phecode
327.7 Sleep related movement disorders Neurological 0.971 0.912 – 1.03 0.346 1106 10777 exclusion phecode
327.71 Restless legs syndrome Neurological 0.977 0.916 – 1.04 0.491 991 9602 exclusion phecode
331 Other cerebral degenerations Neurological 0.93 0.843 – 1.03 0.144 446 4452 exclusion phecode
331.1 Hydrocephalus Neurological 1.02 0.891 – 1.18 0.736 208 2011 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 0.866 0.755 – 0.992 0.0384 232 2401 exclusion phecode
332 Parkinson's disease Neurological 0.943 0.825 – 1.08 0.394 245 2344 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.01 0.965 – 1.07 0.58 1711 16614 exclusion phecode
333.1 Essential tremor Neurological 1.02 0.925 – 1.13 0.647 399 4088 exclusion phecode
333.2 Myoclonus Neurological 1.03 0.837 – 1.27 0.782 96 943 exclusion phecode
333.4 Torsion dystonia Neurological 1.16 1.01 – 1.34 0.0403 201 2129 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 0.98 0.907 – 1.06 0.613 704 6960 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.02 0.765 – 1.37 0.881 51 488 exclusion phecode
334.2 Anterior horn cell disease Neurological 0.819 0.646 – 1.04 0.0988 71 711 exclusion phecode
335 Multiple sclerosis Neurological 0.958 0.845 – 1.09 0.499 264 2750 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.02 0.926 – 1.13 0.64 416 4282 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 0.989 0.828 – 1.18 0.906 126 1424 exclusion phecode
338 Pain Neurological 1 0.982 – 1.03 0.683 13348 17908 exclusion phecode
338.1 Acute pain Neurological 1.01 0.982 – 1.03 0.63 10322 17909 exclusion phecode
338.2 Chronic pain Neurological 0.994 0.966 – 1.02 0.669 6782 17898 exclusion phecode
339 Other headache syndromes Neurological 0.99 0.963 – 1.02 0.47 7191 22406 exclusion phecode
340 Migraine Neurological 0.99 0.958 – 1.02 0.55 4609 19966 exclusion phecode
340.1 Migrain with aura Neurological 0.987 0.945 – 1.03 0.547 2412 15464 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.888 0.706 – 1.12 0.311 81 933 exclusion phecode
342 Hemiplegia Neurological 0.909 0.806 – 1.03 0.122 287 2844 exclusion phecode
343 Infantile cerebral palsy Neurological 1 0.787 – 1.27 0.998 68 677 exclusion phecode
344 Other paralytic syndromes Neurological 0.964 0.875 – 1.06 0.461 443 4560 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.97 0.923 – 1.02 0.228 1731 17261 exclusion phecode
345.1 Epilepsy Neurological 0.958 0.874 – 1.05 0.364 511 5072 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 0.955 0.814 – 1.12 0.575 163 1708 exclusion phecode
345.12 Partial epilepsy Neurological 0.986 0.883 – 1.1 0.807 361 3634 exclusion phecode
345.3 Convulsions Neurological 0.963 0.915 – 1.01 0.144 1636 16259 exclusion phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 1.13 0.919 – 1.38 0.252 106 1144 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.01 0.942 – 1.08 0.782 865 9355 exclusion phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 1.13 0.872 – 1.47 0.35 60 683 exclusion phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 0.824 0.646 – 1.05 0.119 72 725 exclusion phecode
347 Cataplexy and narcolepsy Neurological 1.05 0.818 – 1.34 0.711 62 583 exclusion phecode
348 Other conditions of brain Neurological 0.943 0.886 – 1 0.064 1120 11500 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 0.934 0.858 – 1.02 0.112 595 6189 exclusion phecode
348.4 Cerebral cysts Neurological 0.922 0.784 – 1.09 0.329 163 1638 exclusion phecode
348.7 Coma Neurological 0.86 0.716 – 1.03 0.106 138 1328 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 0.903 0.822 – 0.993 0.0346 483 4842 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 0.989 0.938 – 1.04 0.677 1521 16093 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.965 0.889 – 1.05 0.396 625 6270 exclusion phecode
350 Abnormal movement Neurological 0.975 0.942 – 1.01 0.143 3892 26560 exclusion phecode
350.1 Abnormal involuntary movements Neurological 0.975 0.929 – 1.02 0.296 1883 19381 exclusion phecode
350.2 Abnormality of gait Neurological 0.961 0.92 – 1 0.0789 2237 19825 exclusion phecode
350.3 Lack of coordination Neurological 0.945 0.867 – 1.03 0.193 590 6206 exclusion phecode
350.5 Abnormal reflex Neurological 0.963 0.798 – 1.16 0.697 118 1190 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.919 0.815 – 1.04 0.17 285 3541 exclusion phecode
351 Other peripheral nerve disorders Neurological 0.963 0.932 – 0.994 0.0197 4569 23488 exclusion phecode
352 Disorders of other cranial nerves Neurological 0.956 0.895 – 1.02 0.171 1028 11217 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.92 0.823 – 1.03 0.147 348 3544 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 0.897 0.813 – 0.988 0.0281 451 5071 exclusion phecode
353 Nerve root and plexus disorders Neurological 0.976 0.938 – 1.02 0.244 2719 22770 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.868 0.767 – 0.983 0.0261 265 2626 exclusion phecode
353.2 Nerve root lesions Neurological 0.918 0.725 – 1.16 0.48 76 728 exclusion phecode
355 Complex regional/central pain syndrome Neurological 1.1 0.99 – 1.23 0.0762 351 3538 exclusion phecode
355.1 Chronic pain syndrome Neurological 1.03 0.948 – 1.13 0.446 544 5370 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.951 0.898 – 1.01 0.0869 1300 13214 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 0.946 0.901 – 0.992 0.023 1854 18723 exclusion phecode
358 Myoneural disorders Neurological 0.941 0.869 – 1.02 0.14 664 6759 exclusion phecode
358.1 Myasthenia gravis Neurological 1.05 0.811 – 1.35 0.722 68 670 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.976 0.903 – 1.06 0.545 691 6930 exclusion phecode
359.2 Myopathy Neurological 0.995 0.918 – 1.08 0.903 663 6642 exclusion phecode
360 Disorders of the globe Sense Organs 0.774 0.601 – 0.997 0.0473 71 792 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.969 0.871 – 1.08 0.557 381 4001 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.991 0.844 – 1.16 0.907 161 1671 exclusion phecode
362 Other retinal disorders Sense Organs 0.958 0.911 – 1.01 0.0975 1709 14520 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.952 0.892 – 1.02 0.146 993 9061 exclusion phecode
362.21 Macular degeneration, dry Sense Organs 0.932 0.799 – 1.09 0.366 178 1779 exclusion phecode
362.22 Macular degeneration, wet Sense Organs 1.07 0.835 – 1.38 0.575 69 555 exclusion phecode
362.23 Cystoid macular degeneration of retina Sense Organs 0.897 0.774 – 1.04 0.148 202 2025 exclusion phecode
362.26 Macular puckering of retina Sense Organs 0.948 0.859 – 1.05 0.29 441 4507 exclusion phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.937 0.814 – 1.08 0.369 210 2323 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.947 0.882 – 1.02 0.127 854 7974 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.947 0.86 – 1.04 0.267 466 4825 exclusion phecode
362.31 Separation of retinal layers Sense Organs 0.972 0.843 – 1.12 0.693 212 2232 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.918 0.82 – 1.03 0.135 328 3099 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.965 0.835 – 1.12 0.631 198 2018 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.03 0.83 – 1.29 0.772 83 956 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.933 0.776 – 1.12 0.462 123 1168 exclusion phecode
362.9 Retinal edema Sense Organs 0.993 0.837 – 1.18 0.932 144 1484 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.987 0.873 – 1.12 0.841 264 2741 exclusion phecode
363.3 Chorioretinal scars Sense Organs 1.02 0.875 – 1.19 0.811 178 1788 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.956 0.879 – 1.04 0.301 580 6105 exclusion phecode
364.1 Corneal opacity Sense Organs 1.02 0.889 – 1.16 0.825 234 2348 exclusion phecode
364.2 Corneal edema Sense Organs 0.933 0.727 – 1.2 0.588 65 660 exclusion phecode
364.4 Corneal degenerations Sense Organs 0.933 0.809 – 1.08 0.338 198 2125 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.999 0.881 – 1.13 0.992 255 2696 exclusion phecode
364.51 Fuchs' dystrophy Sense Organs 1.05 0.88 – 1.25 0.603 134 1470 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.877 0.667 – 1.15 0.345 54 515 exclusion phecode
365 Glaucoma Sense Organs 0.945 0.894 – 0.999 0.0469 1376 13132 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 0.886 0.794 – 0.989 0.0316 353 3628 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.825 0.706 – 0.965 0.0159 184 1822 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.12 0.926 – 1.35 0.243 116 1276 exclusion phecode
366 Cataract Sense Organs 0.952 0.919 – 0.986 0.00541 4359 18794 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.828 0.688 – 0.996 0.0447 116 1225 exclusion phecode
366.2 Senile cataract Sense Organs 0.936 0.897 – 0.976 0.00208 2635 16029 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.931 0.903 – 0.96 4.21e-06 5086 26118 exclusion phecode
367.1 Myopia Sense Organs 0.914 0.878 – 0.95 6.52e-06 2868 23722 exclusion phecode
367.2 Astigmatism Sense Organs 0.946 0.905 – 0.988 0.0126 2251 21168 exclusion phecode
367.4 Presbyopia Sense Organs 0.932 0.893 – 0.973 0.00123 2441 19359 exclusion phecode
367.8 Hypermetropia Sense Organs 0.914 0.858 – 0.973 0.00472 1092 11517 exclusion phecode
367.9 Blindness and low vision Sense Organs 0.99 0.918 – 1.07 0.794 736 7528 exclusion phecode
368 Visual disturbances Sense Organs 0.969 0.935 – 1.01 0.0927 3335 26776 exclusion phecode
368.1 Amblyopia Sense Organs 0.924 0.83 – 1.03 0.146 382 3882 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.01 0.93 – 1.09 0.841 633 6450 exclusion phecode
368.3 Anisometropia Sense Organs 0.893 0.745 – 1.07 0.222 126 1332 exclusion phecode
368.4 Visual field defects Sense Organs 0.949 0.876 – 1.03 0.2 649 6710 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.966 0.891 – 1.05 0.399 656 6586 exclusion phecode
368.91 Psychophysical visual disturbances Sense Organs 0.914 0.71 – 1.18 0.483 67 649 exclusion phecode
369 Infection of the eye Sense Organs 0.952 0.908 – 0.999 0.0453 1888 18632 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.963 0.855 – 1.08 0.527 299 3066 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.951 0.903 – 1 0.0581 1611 16285 exclusion phecode
370 Keratitis Sense Organs 0.925 0.858 – 0.998 0.0438 741 8181 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.997 0.839 – 1.18 0.974 132 1343 exclusion phecode
370.2 Superficial keratitis Sense Organs 0.885 0.78 – 1 0.0577 266 3082 exclusion phecode
370.3 Keratoconjunctivitis Sense Organs 0.903 0.81 – 1.01 0.065 358 4059 exclusion phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.85 0.689 – 1.05 0.127 99 1114 exclusion phecode
371 Inflammation of the eye Sense Organs 0.946 0.907 – 0.988 0.0123 2355 21087 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.836 0.739 – 0.944 0.00403 287 3083 exclusion phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.972 0.889 – 1.06 0.529 535 5347 exclusion phecode
371.21 Allergic conjunctivitis Sense Organs 0.955 0.865 – 1.05 0.363 439 4367 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.953 0.907 – 1 0.0598 1739 17269 exclusion phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 0.903 0.711 – 1.15 0.404 76 805 exclusion phecode
372 Disorders of conjunctiva Sense Organs 0.974 0.893 – 1.06 0.544 558 6310 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.925 0.875 – 0.978 0.00621 1382 14445 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.983 0.842 – 1.15 0.828 169 2337 exclusion phecode
374.2 Lagophthalmos Sense Organs 0.984 0.817 – 1.19 0.869 113 1523 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.918 0.841 – 1 0.0565 554 6161 exclusion phecode
374.6 Dermatochalasis Sense Organs 0.941 0.857 – 1.03 0.195 481 5455 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.94 0.897 – 0.987 0.0119 1924 16718 exclusion phecode
375.1 Dry eyes Sense Organs 0.917 0.877 – 0.96 0.000212 2155 17380 exclusion phecode
375.2 Epiphora Sense Organs 0.931 0.812 – 1.07 0.301 231 2712 exclusion phecode
376 Disorders of the orbit Sense Organs 0.862 0.749 – 0.992 0.0383 220 2359 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.921 0.843 – 1.01 0.0681 559 5653 exclusion phecode
377.1 Optic atrophy Sense Organs 0.958 0.808 – 1.14 0.623 145 1595 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.903 0.812 – 1 0.0613 382 3778 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.951 0.883 – 1.03 0.194 769 7748 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.901 0.821 – 0.989 0.0276 485 4929 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.2 0.992 – 1.45 0.0612 123 1136 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.02 0.882 – 1.17 0.82 214 2200 exclusion phecode
379 Other disorders of eye Sense Organs 0.965 0.926 – 1.01 0.101 2540 19862 exclusion phecode
379.1 Scleritis and episcleritis Sense Organs 1.2 0.993 – 1.46 0.0592 108 1161 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.955 0.908 – 1 0.0704 1747 14403 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.828 0.641 – 1.07 0.151 59 629 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.03 0.877 – 1.2 0.743 176 1855 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1 0.854 – 1.18 0.965 162 1656 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.938 0.866 – 1.02 0.117 685 7157 exclusion phecode
380 Disorders of external ear Sense Organs 0.939 0.881 – 1 0.0503 1098 12041 exclusion phecode
380.1 Otitis externa Sense Organs 0.883 0.824 – 0.946 0.00041 891 9185 exclusion phecode
380.4 Impacted cerumen Sense Organs 0.924 0.874 – 0.977 0.00553 1398 14538 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.967 0.929 – 1.01 0.1 2705 24404 exclusion phecode
381.1 Otitis media Sense Organs 0.958 0.915 – 1 0.0669 2019 19906 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.953 0.907 – 1 0.0584 1726 17115 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.971 0.912 – 1.03 0.348 1102 11529 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.938 0.768 – 1.15 0.53 107 1062 exclusion phecode
381.9 Otorrhea Sense Organs 1.08 0.944 – 1.23 0.267 230 2410 exclusion phecode
382 Otalgia Sense Organs 1 0.941 – 1.06 0.997 1153 11878 exclusion phecode
383 Otosclerosis Sense Organs 0.971 0.788 – 1.2 0.784 96 925 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.01 0.897 – 1.13 0.924 329 3308 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 0.992 0.874 – 1.13 0.9 264 2667 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.966 0.858 – 1.09 0.566 302 3070 exclusion phecode
385.3 Cholesteatoma Sense Organs 0.999 0.868 – 1.15 0.992 212 2108 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.818 0.656 – 1.02 0.0731 90 877 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.985 0.926 – 1.05 0.638 1110 11329 exclusion phecode
386.1 Meniere's disease Sense Organs 1.12 0.968 – 1.3 0.128 194 1977 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.988 0.923 – 1.06 0.73 914 9464 exclusion phecode
386.21 Central origin vertigo Sense Organs 1.01 0.938 – 1.1 0.712 677 6922 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.01 0.942 – 1.08 0.757 858 8697 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.977 0.945 – 1.01 0.166 4157 25776 exclusion phecode
388 Other disorders of ear Sense Organs 1.01 0.93 – 1.11 0.743 540 5743 exclusion phecode
389 Hearing loss Sense Organs 0.975 0.944 – 1.01 0.117 4493 26476 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.971 0.929 – 1.02 0.199 2239 19460 exclusion phecode
389.2 Conductive hearing loss Sense Organs 0.963 0.885 – 1.05 0.388 612 6130 exclusion phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.908 0.74 – 1.12 0.358 99 997 exclusion phecode
389.4 Tinnitus Sense Organs 0.993 0.937 – 1.05 0.822 1250 13371 exclusion phecode
389.5 Disorders of acoustic nerve Sense Organs 1.28 1.02 – 1.59 0.0327 80 840 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1 0.934 – 1.07 0.992 882 8338 exclusion phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 0.861 0.745 – 0.994 0.0417 201 1998 exclusion phecode
394.2 Mitral valve disease Circulatory System 0.978 0.866 – 1.1 0.718 277 2734 exclusion phecode
394.3 Aortic valve disease Circulatory System 0.872 0.718 – 1.06 0.169 116 1037 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.05 0.946 – 1.18 0.338 362 3394 exclusion phecode
395 Heart valve disorders Circulatory System 1.01 0.966 – 1.05 0.716 2393 18786 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.01 0.954 – 1.07 0.747 1334 12948 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.969 0.912 – 1.03 0.305 1199 10314 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.09 0.968 – 1.24 0.152 277 2739 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.08 0.841 – 1.38 0.554 71 698 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.02 0.94 – 1.1 0.653 666 5958 exclusion phecode
396 Abnormal heart sounds Circulatory System 0.979 0.942 – 1.02 0.299 2873 22952 exclusion phecode
401 Hypertension Circulatory System 0.991 0.966 – 1.02 0.474 14395 16444 exclusion phecode
401.1 Essential hypertension Circulatory System 0.99 0.966 – 1.02 0.459 14298 16443 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.01 0.956 – 1.06 0.807 1916 9840 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1 0.902 – 1.11 0.973 404 3539 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.02 0.963 – 1.08 0.499 1484 8833 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1 0.947 – 1.06 0.983 1517 10686 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 0.94 0.892 – 0.991 0.0209 1639 12783 exclusion phecode
411 Ischemic Heart Disease Circulatory System 0.987 0.955 – 1.02 0.418 5149 20530 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.02 0.934 – 1.12 0.632 517 4963 exclusion phecode
411.2 Myocardial infarction Circulatory System 1 0.955 – 1.05 0.971 2051 13892 exclusion phecode
411.3 Angina pectoris Circulatory System 0.988 0.934 – 1.04 0.664 1414 11570 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 0.989 0.956 – 1.02 0.552 4389 18157 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.04 0.835 – 1.29 0.726 87 869 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.992 0.955 – 1.03 0.658 3618 16642 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.02 0.893 – 1.17 0.757 251 2342 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.02 0.967 – 1.07 0.523 1819 14350 exclusion phecode
414.2 ASCVD Circulatory System 0.975 0.875 – 1.09 0.651 359 3518 exclusion phecode
415 Pulmonary heart disease Circulatory System 0.974 0.931 – 1.02 0.253 2125 19492 exclusion phecode
415.1 Acute pulmonary heart disease Circulatory System 0.97 0.913 – 1.03 0.329 1176 11669 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.973 0.915 – 1.03 0.368 1173 11647 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.987 0.929 – 1.05 0.674 1175 11151 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1 0.908 – 1.1 0.999 459 4449 exclusion phecode
416 Cardiomegaly Circulatory System 0.99 0.916 – 1.07 0.79 715 7040 exclusion phecode
418 Nonspecific chest pain Circulatory System 0.977 0.952 – 1 0.0791 7861 23296 exclusion phecode
418.1 Precordial pain Circulatory System 1.01 0.941 – 1.08 0.815 900 9076 exclusion phecode
420 Carditis Circulatory System 0.973 0.911 – 1.04 0.419 985 9663 exclusion phecode
420.1 Myocarditis Circulatory System 0.856 0.656 – 1.12 0.255 61 604 exclusion phecode
420.2 Pericarditis Circulatory System 0.997 0.911 – 1.09 0.947 533 5284 exclusion phecode
420.21 Acute pericarditis Circulatory System 0.999 0.823 – 1.21 0.991 116 1162 exclusion phecode
420.22 Chronic pericarditis Circulatory System 0.963 0.756 – 1.23 0.764 72 720 exclusion phecode
420.3 Endocarditis Circulatory System 0.981 0.89 – 1.08 0.701 455 4453 exclusion phecode
425 Cardiomyopathy Circulatory System 0.997 0.94 – 1.06 0.917 1232 11886 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.994 0.936 – 1.06 0.844 1192 11406 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.05 0.881 – 1.26 0.563 133 1303 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.09 0.905 – 1.31 0.369 121 1211 exclusion phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.08 0.924 – 1.25 0.348 187 1969 exclusion phecode
426 Cardiac conduction disorders Circulatory System 0.991 0.963 – 1.02 0.549 7564 17764 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 0.972 0.911 – 1.04 0.394 1114 7318 exclusion phecode
426.21 First degree AV block Circulatory System 0.943 0.872 – 1.02 0.143 766 5566 exclusion phecode
426.23 Second degree AV block Circulatory System 1.06 0.868 – 1.31 0.548 113 991 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 0.952 0.834 – 1.09 0.471 258 2156 exclusion phecode
426.25 Other heart block Circulatory System 1.06 0.873 – 1.29 0.55 112 1034 exclusion phecode
426.3 Bundle branch block Circulatory System 0.976 0.919 – 1.04 0.439 1292 8787 exclusion phecode
426.31 Right bundle branch block Circulatory System 0.985 0.914 – 1.06 0.696 797 6621 exclusion phecode
426.32 Left bundle branch block Circulatory System 0.954 0.87 – 1.05 0.317 530 4556 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.871 0.664 – 1.14 0.316 56 546 exclusion phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 0.993 0.963 – 1.02 0.628 6492 17639 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 0.978 0.874 – 1.09 0.702 347 3455 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.986 0.92 – 1.06 0.704 943 6666 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.954 0.873 – 1.04 0.293 590 4472 exclusion phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.02 0.924 – 1.12 0.736 489 4172 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 0.987 0.962 – 1.01 0.28 11006 17863 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 0.972 0.92 – 1.03 0.319 1463 11835 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.991 0.926 – 1.06 0.79 940 8875 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.92 0.847 – 0.998 0.0459 669 6084 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 0.978 0.937 – 1.02 0.297 3051 12378 exclusion phecode
427.21 Atrial fibrillation Circulatory System 0.979 0.937 – 1.02 0.323 2976 12217 exclusion phecode
427.22 Atrial flutter Circulatory System 1 0.939 – 1.07 0.999 1187 7369 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.979 0.949 – 1.01 0.18 5520 17820 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.896 0.798 – 1.01 0.0651 327 3129 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.812 0.675 – 0.977 0.0271 128 1242 exclusion phecode
427.42 Cardiac arrest Circulatory System 0.922 0.809 – 1.05 0.223 259 2450 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.987 0.953 – 1.02 0.45 4189 17814 exclusion phecode
427.6 Premature beats Circulatory System 0.964 0.91 – 1.02 0.216 1357 10406 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 0.892 0.801 – 0.993 0.0372 381 3608 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.01 0.971 – 1.05 0.668 3187 17832 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.952 0.869 – 1.04 0.299 519 4559 exclusion phecode
427.9 Palpitations Circulatory System 0.991 0.951 – 1.03 0.664 2716 16745 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.958 0.918 – 1 0.0537 2514 15756 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 0.956 0.913 – 1 0.0503 2236 15031 exclusion phecode
428.2 Heart failure NOS Circulatory System 0.977 0.932 – 1.02 0.34 2097 14010 exclusion phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 0.997 0.932 – 1.07 0.92 994 8567 exclusion phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 0.961 0.896 – 1.03 0.268 894 7866 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 0.983 0.956 – 1.01 0.204 7311 22864 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1 0.926 – 1.09 0.927 647 6111 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.964 0.929 – 1 0.0575 3366 19398 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 0.985 0.956 – 1.01 0.318 5562 22731 exclusion phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 0.937 0.85 – 1.03 0.195 454 4272 exclusion phecode
430 Intracranial hemorrhage Circulatory System 0.991 0.903 – 1.09 0.853 487 4881 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.992 0.855 – 1.15 0.92 188 1767 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 0.899 0.788 – 1.03 0.115 242 2445 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.04 0.881 – 1.23 0.649 159 1508 exclusion phecode
433 Cerebrovascular disease Circulatory System 1 0.964 – 1.04 0.935 3212 21152 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.995 0.934 – 1.06 0.868 1091 9474 exclusion phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.08 0.909 – 1.28 0.393 147 1358 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.993 0.94 – 1.05 0.797 1439 13399 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.994 0.94 – 1.05 0.827 1387 12926 exclusion phecode
433.3 Cerebral ischemia Circulatory System 0.989 0.938 – 1.04 0.69 1518 13735 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 0.985 0.93 – 1.04 0.595 1322 12123 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.03 0.927 – 1.15 0.548 349 3219 exclusion phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1 0.889 – 1.14 0.944 283 2792 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.985 0.887 – 1.09 0.769 400 4007 exclusion phecode
440 Atherosclerosis Circulatory System 0.99 0.938 – 1.05 0.724 1468 12541 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.13 0.952 – 1.33 0.165 144 1365 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.98 0.913 – 1.05 0.569 877 8371 exclusion phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.01 0.845 – 1.21 0.907 137 1368 exclusion phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1 0.92 – 1.09 0.996 617 5845 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 0.987 0.902 – 1.08 0.77 527 4865 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.04 0.929 – 1.16 0.506 344 3149 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.06 0.904 – 1.24 0.486 172 1590 exclusion phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.08 0.885 – 1.31 0.463 105 915 exclusion phecode
442 Other aneurysm Circulatory System 1.02 0.973 – 1.08 0.377 1761 13961 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1 0.946 – 1.06 0.9 1262 10381 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.06 0.978 – 1.14 0.163 728 6491 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.21 1.02 – 1.45 0.0324 133 1242 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.08 0.893 – 1.31 0.427 116 1003 exclusion phecode
442.4 Arterial dissection Circulatory System 1.03 0.854 – 1.24 0.755 125 1192 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.13 0.993 – 1.28 0.064 258 2513 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.02 0.968 – 1.07 0.508 1823 15932 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.07 0.978 – 1.17 0.143 500 5023 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.01 0.832 – 1.24 0.885 103 1029 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.02 0.964 – 1.07 0.541 1480 13483 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.01 0.95 – 1.06 0.845 1326 11425 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.02 0.93 – 1.11 0.733 536 5153 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.05 0.911 – 1.22 0.486 202 1782 exclusion phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 0.871 0.709 – 1.07 0.187 101 955 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.03 0.907 – 1.16 0.682 279 2868 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.796 0.619 – 1.02 0.0753 65 693 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.09 0.935 – 1.28 0.265 178 1813 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.02 0.965 – 1.07 0.528 1607 14617 exclusion phecode
447.1 Stricture of artery Circulatory System 1.08 0.965 – 1.21 0.182 344 3265 exclusion phecode
447.7 Aortic ectasia Circulatory System 0.979 0.888 – 1.08 0.667 461 4705 exclusion phecode
448 Disease of capillaries Circulatory System 0.944 0.852 – 1.05 0.275 397 6572 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.934 0.877 – 0.995 0.0342 1057 13663 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.991 0.899 – 1.09 0.857 449 4643 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.992 0.833 – 1.18 0.924 150 1528 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 0.965 0.928 – 1 0.0711 2963 20767 exclusion phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 0.996 0.853 – 1.16 0.962 174 1826 exclusion phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 0.974 0.93 – 1.02 0.264 2062 18336 exclusion phecode
452.8 Postphlebitic syndrome Circulatory System 1.08 0.887 – 1.32 0.444 109 1026 exclusion phecode
453 Chronic venous hypertension Circulatory System 0.974 0.815 – 1.16 0.769 136 1379 exclusion phecode
454 Varicose veins Circulatory System 0.958 0.912 – 1.01 0.0971 1717 16542 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 0.948 0.898 – 1 0.0564 1446 14177 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.954 0.89 – 1.02 0.185 879 9446 exclusion phecode
455 Hemorrhoids Circulatory System 0.959 0.924 – 0.995 0.027 3337 20307 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.948 0.902 – 0.996 0.0334 1793 16537 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.958 0.906 – 1.01 0.135 1423 10987 exclusion phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 0.986 0.853 – 1.14 0.849 211 2118 exclusion phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 0.963 0.909 – 1.02 0.192 1348 10597 exclusion phecode
458 Hypotension Circulatory System 0.987 0.951 – 1.03 0.511 3091 23115 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.03 0.953 – 1.11 0.484 763 7873 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.02 0.946 – 1.11 0.567 693 6898 exclusion phecode
458.9 Hypotension NOS Circulatory System 0.981 0.943 – 1.02 0.344 2764 22117 exclusion phecode
459 Other disorders of circulatory system Circulatory System 0.981 0.943 – 1.02 0.351 2737 22290 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 0.967 0.878 – 1.06 0.492 455 4751 exclusion phecode
459.7 Blood vessel replaced Circulatory System 1.04 0.891 – 1.22 0.609 170 1546 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 0.973 0.93 – 1.02 0.243 2093 18677 exclusion phecode
464 Acute sinusitis Respiratory 0.94 0.904 – 0.977 0.00167 2981 21865 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.945 0.918 – 0.972 0.000117 5867 24594 exclusion phecode
465.2 Acute pharyngitis Respiratory 0.954 0.919 – 0.99 0.0127 3354 22211 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.994 0.877 – 1.13 0.92 266 2844 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.971 0.915 – 1.03 0.344 1184 12061 exclusion phecode
471 Nasal polyps Respiratory 0.87 0.784 – 0.966 0.00883 390 3922 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.946 0.889 – 1.01 0.0824 1084 10935 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 0.953 0.907 – 1 0.0518 1788 17072 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.983 0.887 – 1.09 0.743 408 4118 exclusion phecode
473.4 Voice disturbance Respiratory 0.956 0.904 – 1.01 0.108 1394 14492 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 0.965 0.888 – 1.05 0.4 618 5584 exclusion phecode
474.1 Acute tonsillitis Respiratory 0.958 0.842 – 1.09 0.514 258 2337 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.965 0.879 – 1.06 0.448 496 4666 exclusion phecode
475 Chronic sinusitis Respiratory 0.929 0.892 – 0.967 0.000339 2774 19126 exclusion phecode
475.9 Postnasal drip Respiratory 0.889 0.809 – 0.977 0.0145 484 5170 exclusion phecode
476 Allergic rhinitis Respiratory 0.963 0.938 – 0.989 0.00496 8157 19306 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 0.955 0.882 – 1.03 0.26 672 7131 exclusion phecode
478 Throat pain Respiratory 0.963 0.844 – 1.1 0.582 241 2695 exclusion phecode
479 Other upper respiratory disease Respiratory 0.972 0.937 – 1.01 0.132 3438 19291 exclusion phecode
480 Pneumonia Respiratory 0.968 0.935 – 1 0.067 3719 25272 exclusion phecode
480.1 Bacterial pneumonia Respiratory 0.925 0.853 – 1 0.0638 625 6733 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 0.97 0.858 – 1.1 0.629 269 2955 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 0.834 0.674 – 1.03 0.0964 87 947 exclusion phecode
480.13 MRSA pneumonia Respiratory 0.857 0.664 – 1.11 0.239 64 653 exclusion phecode
480.2 Viral pneumonia Respiratory 0.949 0.766 – 1.18 0.632 96 1154 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.89 0.719 – 1.1 0.282 83 913 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.08 0.876 – 1.34 0.458 92 898 exclusion phecode
481 Influenza Respiratory 0.911 0.846 – 0.982 0.0153 774 8133 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.93 0.888 – 0.973 0.00174 2077 19628 exclusion phecode
495 Asthma Respiratory 0.984 0.956 – 1.01 0.278 5838 22618 exclusion phecode
495.1 Chronic obstructive asthma Respiratory 0.987 0.87 – 1.12 0.839 274 2632 exclusion phecode
495.2 Asthma with exacerbation Respiratory 0.955 0.896 – 1.02 0.158 1068 10524 exclusion phecode
496 Chronic airway obstruction Respiratory 0.99 0.954 – 1.03 0.586 3397 18947 exclusion phecode
496.1 Emphysema Respiratory 0.985 0.931 – 1.04 0.601 1345 12607 exclusion phecode
496.2 Chronic bronchitis Respiratory 1 0.962 – 1.04 0.909 2599 17804 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.01 0.963 – 1.05 0.802 2360 16909 exclusion phecode
496.3 Bronchiectasis Respiratory 0.94 0.836 – 1.06 0.301 313 3225 exclusion phecode
497 Bronchitis Respiratory 0.988 0.929 – 1.05 0.688 1154 11728 exclusion phecode
498 Acute bronchospasm Respiratory 0.936 0.834 – 1.05 0.265 317 3123 exclusion phecode
499 Cystic fibrosis Respiratory 0.925 0.748 – 1.14 0.47 93 977 exclusion phecode
500 Lung disease due to external agents Respiratory 1.14 1.01 – 1.28 0.036 288 3211 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.26 0.961 – 1.64 0.0951 57 617 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 0.984 0.882 – 1.1 0.777 360 3812 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.965 0.876 – 1.06 0.473 456 4567 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 0.983 0.899 – 1.07 0.697 548 5197 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.04 0.928 – 1.16 0.523 337 3324 exclusion phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 0.927 0.797 – 1.08 0.323 180 1829 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 0.961 0.902 – 1.02 0.222 1051 10125 exclusion phecode
506 Empyema and pneumothorax Respiratory 0.963 0.919 – 1.01 0.106 2049 17721 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 0.966 0.92 – 1.01 0.161 1836 17144 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.978 0.928 – 1.03 0.407 1527 15072 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.99 0.948 – 1.03 0.64 2361 18987 exclusion phecode
509.1 Respiratory failure Respiratory 0.957 0.9 – 1.02 0.168 1133 11276 exclusion phecode
509.2 Respiratory insufficiency Respiratory 0.943 0.874 – 1.02 0.131 723 7097 exclusion phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 0.979 0.922 – 1.04 0.496 1195 11433 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.01 0.933 – 1.1 0.773 666 6556 exclusion phecode
510 Other diseases of lung Respiratory 1 0.968 – 1.04 0.848 3418 24461 exclusion phecode
510.2 Lung transplant Respiratory 0.809 0.641 – 1.02 0.0738 82 1015 exclusion phecode
512 Other symptoms of respiratory system Respiratory 0.967 0.945 – 0.99 0.00466 11885 19371 exclusion phecode
512.1 Wheezing Respiratory 0.963 0.896 – 1.03 0.302 824 8539 exclusion phecode
512.2 Painful respiration Respiratory 0.937 0.887 – 0.991 0.0216 1376 13799 exclusion phecode
512.3 Abnormal chest sounds Respiratory 0.979 0.833 – 1.15 0.801 156 1651 exclusion phecode
512.7 Shortness of breath Respiratory 0.974 0.946 – 1 0.0817 6233 19347 exclusion phecode
512.8 Cough Respiratory 0.949 0.921 – 0.978 0.000691 5685 19367 exclusion phecode
512.9 Other dyspnea Respiratory 0.963 0.936 – 0.99 0.00752 6886 19362 exclusion phecode
513 Respiratory abnormalities Respiratory 0.972 0.947 – 0.998 0.0318 8136 23106 exclusion phecode
513.3 Hypoventilation Respiratory 0.916 0.835 – 1.01 0.0658 494 4837 exclusion phecode
513.31 Apnea Respiratory 0.917 0.808 – 1.04 0.178 258 2485 exclusion phecode
513.32 Orthopnea Respiratory 0.883 0.737 – 1.06 0.175 126 1250 exclusion phecode
513.4 Hyperventilation Respiratory 0.981 0.876 – 1.1 0.735 326 3338 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.08 0.916 – 1.28 0.353 153 1508 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 0.976 0.939 – 1.01 0.202 3067 23798 exclusion phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 0.926 0.777 – 1.1 0.39 133 1472 exclusion phecode
514.2 Solitary pulmonary nodule Respiratory 0.973 0.926 – 1.02 0.29 1695 17930 exclusion phecode
516 Abnormal sputum Respiratory 1.02 0.915 – 1.13 0.776 402 4392 exclusion phecode
516.1 Hemoptysis Respiratory 1.02 0.913 – 1.14 0.731 350 3682 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.97 0.938 – 1 0.0818 3952 26218 exclusion phecode
519.1 Tracheostomy complications Respiratory 0.927 0.769 – 1.12 0.423 121 1382 exclusion phecode
519.2 Respiratory complications Respiratory 1.03 0.911 – 1.16 0.67 307 2944 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.954 0.88 – 1.03 0.258 652 7077 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.952 0.916 – 0.988 0.0105 3072 23541 exclusion phecode
520 Disorders of tooth development Digestive 0.972 0.851 – 1.11 0.677 233 2491 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.973 0.787 – 1.2 0.804 88 1085 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.981 0.835 – 1.15 0.811 157 1496 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.01 0.927 – 1.11 0.763 512 5924 exclusion phecode
521.1 Dental caries Digestive 1.04 0.944 – 1.14 0.444 474 5536 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1 0.899 – 1.12 0.975 339 3386 exclusion phecode
522.5 Periapical abscess Digestive 0.986 0.876 – 1.11 0.822 287 2820 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.03 0.933 – 1.13 0.571 414 4671 exclusion phecode
523.1 Gingivitis Digestive 0.955 0.764 – 1.19 0.686 79 972 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 0.942 0.828 – 1.07 0.368 228 2368 exclusion phecode
523.31 Acute periodontitis Digestive 0.991 0.86 – 1.14 0.902 190 2062 exclusion phecode
523.32 Chronic periodontitis Digestive 0.854 0.671 – 1.09 0.198 67 824 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.981 0.866 – 1.11 0.76 272 2735 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.02 0.871 – 1.2 0.797 169 1692 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.03 0.947 – 1.11 0.522 653 7154 exclusion phecode
525.1 Loss of teeth or edentulism Digestive 0.965 0.841 – 1.11 0.612 230 2638 exclusion phecode
526 Diseases of the jaws Digestive 0.982 0.934 – 1.03 0.474 1725 17771 exclusion phecode
526.1 Cysts of the jaws Digestive 1.01 0.869 – 1.18 0.865 186 1782 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.02 0.874 – 1.18 0.844 189 1873 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 0.991 0.928 – 1.06 0.794 998 10053 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1 0.934 – 1.08 0.897 802 8033 exclusion phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 1.03 0.936 – 1.12 0.582 517 5214 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.881 0.751 – 1.03 0.123 152 1967 exclusion phecode
526.9 Jaw disease NOS Digestive 1.02 0.907 – 1.16 0.699 284 3243 exclusion phecode
527 Diseases of the salivary glands Digestive 0.95 0.887 – 1.02 0.15 876 10809 exclusion phecode
527.2 Sialoadenitis Digestive 0.884 0.778 – 1 0.056 262 2570 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 0.999 0.902 – 1.11 0.988 390 5570 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 0.983 0.826 – 1.17 0.842 133 1545 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.942 0.892 – 0.994 0.029 1447 16995 exclusion phecode
528.1 Stomatitis and mucositis Digestive 0.953 0.855 – 1.06 0.378 364 4426 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.92 0.754 – 1.12 0.415 107 1354 exclusion phecode
528.12 Oral aphthae Digestive 0.886 0.739 – 1.06 0.189 129 1433 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.02 0.857 – 1.21 0.834 138 1553 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.948 0.774 – 1.16 0.603 96 892 exclusion phecode
528.41 Cyst of the salivary gland Digestive 1.03 0.795 – 1.33 0.821 56 562 exclusion phecode
528.5 Diseases of lips Digestive 1.01 0.879 – 1.17 0.858 209 2739 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 0.931 0.715 – 1.21 0.595 54 869 exclusion phecode
528.7 Sialolithiasis Digestive 0.829 0.686 – 1 0.0525 116 1070 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1 0.897 – 1.11 0.998 346 4285 exclusion phecode
529.1 Glossitis Digestive 0.926 0.714 – 1.2 0.565 67 771 exclusion phecode
529.6 Glossodynia Digestive 1.06 0.861 – 1.31 0.568 92 1056 exclusion phecode
530 Diseases of esophagus Digestive 0.977 0.954 – 1 0.0566 11047 19162 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.977 0.953 – 1 0.0593 10685 19159 exclusion phecode
530.11 GERD Digestive 0.976 0.953 – 1 0.0563 10413 19159 exclusion phecode
530.12 Ulcer of esophagus Digestive 0.938 0.818 – 1.08 0.363 230 2328 exclusion phecode
530.13 Barrett's esophagus Digestive 0.954 0.868 – 1.05 0.337 474 4674 exclusion phecode
530.14 Reflux esophagitis Digestive 0.962 0.905 – 1.02 0.218 1133 11236 exclusion phecode
530.15 Eosinophilic esophagitis Digestive 0.88 0.73 – 1.06 0.177 122 1245 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.963 0.865 – 1.07 0.497 369 3737 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 0.971 0.89 – 1.06 0.505 570 5781 exclusion phecode
530.5 Disorders of esophageal motility Digestive 0.988 0.884 – 1.1 0.823 350 3356 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.845 0.68 – 1.05 0.129 95 846 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.901 0.68 – 1.19 0.469 54 544 exclusion phecode
530.9 Heartburn Digestive 0.994 0.93 – 1.06 0.855 947 9782 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.05 0.988 – 1.11 0.117 1265 12500 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.03 0.902 – 1.19 0.628 234 2273 exclusion phecode
531.2 Gastric ulcer Digestive 1.02 0.938 – 1.1 0.707 693 6929 exclusion phecode
531.3 Duodenal ulcer Digestive 1.12 0.986 – 1.26 0.0837 280 2741 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.06 0.964 – 1.16 0.24 499 4858 exclusion phecode
531.5 Gastrojejunal ulcer Digestive 1.24 1.01 – 1.53 0.0415 97 912 exclusion phecode
532 Dysphagia Digestive 0.987 0.95 – 1.02 0.488 3277 18348 exclusion phecode
535 Gastritis and duodenitis Digestive 0.953 0.906 – 1 0.063 1693 16988 exclusion phecode
535.1 Acute gastritis Digestive 0.976 0.9 – 1.06 0.558 646 6430 exclusion phecode
535.2 Atrophic gastritis Digestive 0.996 0.866 – 1.14 0.951 213 2013 exclusion phecode
535.6 Duodenitis Digestive 0.981 0.85 – 1.13 0.788 209 2084 exclusion phecode
535.8 Other specified gastritis Digestive 0.939 0.845 – 1.04 0.246 390 3922 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.931 0.864 – 1 0.0567 780 7932 exclusion phecode
536 Disorders of function of stomach Digestive 0.962 0.916 – 1.01 0.119 1776 18086 exclusion phecode
536.3 Gastroparesis Digestive 0.93 0.839 – 1.03 0.172 392 4057 exclusion phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.05 0.921 – 1.19 0.472 253 2641 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.955 0.903 – 1.01 0.111 1340 13634 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 0.97 0.925 – 1.02 0.207 1880 18528 exclusion phecode
537.1 Lesions of stomach and duodenum Digestive 0.886 0.717 – 1.09 0.261 97 936 exclusion phecode
539 Bariatric surgery Digestive 0.939 0.879 – 1 0.0605 996 9391 exclusion phecode
540 Appendiceal conditions Digestive 0.959 0.858 – 1.07 0.466 334 3348 exclusion phecode
540.1 Appendicitis Digestive 0.951 0.846 – 1.07 0.406 295 2937 exclusion phecode
540.11 Acute appendicitis Digestive 0.929 0.816 – 1.06 0.26 250 2468 exclusion phecode
550 Abdominal hernia Digestive 0.994 0.962 – 1.03 0.701 4362 25298 exclusion phecode
550.1 Inguinal hernia Digestive 0.967 0.907 – 1.03 0.299 1068 10437 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.03 0.985 – 1.09 0.176 1768 16477 exclusion phecode
550.3 Femoral hernia Digestive 0.981 0.784 – 1.23 0.867 84 864 exclusion phecode
550.4 Umbilical hernia Digestive 0.92 0.857 – 0.987 0.0205 872 8315 exclusion phecode
550.5 Ventral hernia Digestive 1.01 0.959 – 1.07 0.662 1484 14153 exclusion phecode
550.6 Incisional hernia Digestive 1.02 0.949 – 1.09 0.642 908 8582 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.06 0.991 – 1.13 0.0953 1058 10518 exclusion phecode
555.1 Regional enteritis Digestive 1.06 0.981 – 1.15 0.138 674 6569 exclusion phecode
555.2 Ulcerative colitis Digestive 1.08 0.998 – 1.18 0.0557 624 6365 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.13 1.02 – 1.26 0.024 370 3733 exclusion phecode
556 Ulceration of the lower GI tract Digestive 0.884 0.79 – 0.989 0.0311 355 3632 exclusion phecode
556.1 Ulceration of intestine Digestive 0.889 0.789 – 1 0.0549 309 3158 exclusion phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 0.862 0.706 – 1.05 0.147 100 1053 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.942 0.885 – 1 0.0581 1125 10609 exclusion phecode
557.1 Celiac disease Digestive 0.95 0.837 – 1.08 0.427 258 2552 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.02 0.978 – 1.07 0.311 2170 16925 exclusion phecode
559 Ileostomy status Digestive 0.987 0.91 – 1.07 0.753 652 6138 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.03 0.982 – 1.08 0.232 2086 16644 exclusion phecode
560.1 Paralytic ileus Digestive 1.07 1 – 1.13 0.0371 1165 10720 exclusion phecode
560.2 Impaction of intestine Digestive 0.909 0.786 – 1.05 0.202 207 2068 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.06 0.921 – 1.23 0.403 202 2075 exclusion phecode
560.4 Other intestinal obstruction Digestive 1.02 0.958 – 1.08 0.589 1209 11624 exclusion phecode
561 Symptoms involving digestive system Digestive 0.985 0.956 – 1.01 0.315 6126 18301 exclusion phecode
561.1 Diarrhea Digestive 0.991 0.959 – 1.02 0.598 4673 18304 exclusion phecode
561.2 Flatulence Digestive 0.97 0.925 – 1.02 0.222 1888 15581 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 0.989 0.952 – 1.03 0.551 3609 14902 exclusion phecode
562.1 Diverticulosis Digestive 0.99 0.953 – 1.03 0.597 3582 14852 exclusion phecode
562.2 Diverticulitis Digestive 0.995 0.931 – 1.06 0.874 973 9531 exclusion phecode
563 Constipation Digestive 0.995 0.962 – 1.03 0.763 4394 18269 exclusion phecode
564 Functional digestive disorders Digestive 0.991 0.965 – 1.02 0.534 7604 18299 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.01 0.963 – 1.05 0.777 2303 14300 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 0.996 0.949 – 1.05 0.876 1861 15215 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 0.975 0.922 – 1.03 0.38 1392 13383 exclusion phecode
565 Anal and rectal conditions Digestive 1.02 0.975 – 1.07 0.372 1980 19680 exclusion phecode
565.1 Anal and rectal polyp Digestive 0.991 0.915 – 1.07 0.817 678 7078 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.02 0.951 – 1.09 0.622 962 9176 exclusion phecode
568 Other disorders of peritoneum Digestive 1.01 0.953 – 1.07 0.707 1212 11520 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.06 0.989 – 1.13 0.0986 920 8532 exclusion phecode
569 Other disorders of intestine Digestive 0.991 0.961 – 1.02 0.568 5006 24155 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.912 0.787 – 1.06 0.222 190 2003 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.02 0.952 – 1.08 0.645 1014 9661 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 0.982 0.944 – 1.02 0.361 2845 22322 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 0.98 0.941 – 1.02 0.324 2665 22059 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.979 0.902 – 1.06 0.616 629 6182 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 0.94 0.78 – 1.13 0.514 126 1198 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1 0.92 – 1.09 0.993 615 5888 exclusion phecode
571.81 Portal hypertension Digestive 0.961 0.862 – 1.07 0.47 360 3469 exclusion phecode
572 Ascites (non malignant) Digestive 1.03 0.976 – 1.08 0.295 1520 15113 exclusion phecode
573 Other disorders of liver Digestive 0.991 0.956 – 1.03 0.627 3437 23010 exclusion phecode
573.1 Chronic passive congestion of liver Digestive 0.87 0.693 – 1.09 0.231 82 809 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.01 0.861 – 1.19 0.892 159 1810 exclusion phecode
573.3 Hepatomegaly Digestive 0.969 0.856 – 1.1 0.618 271 2757 exclusion phecode
573.4 Acute and subacute necrosis of liver Digestive 0.878 0.76 – 1.01 0.0749 208 2098 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.01 0.926 – 1.1 0.835 579 5978 exclusion phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 0.994 0.942 – 1.05 0.813 1507 15908 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 0.971 0.923 – 1.02 0.251 1661 16882 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1 0.96 – 1.04 0.974 2542 22919 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.01 0.968 – 1.06 0.595 2149 20520 exclusion phecode
574.1 Cholelithiasis Digestive 0.997 0.952 – 1.04 0.898 1975 19131 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.05 0.908 – 1.21 0.532 214 2055 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.985 0.887 – 1.09 0.778 378 3614 exclusion phecode
574.2 Calculus of bile duct Digestive 0.999 0.917 – 1.09 0.983 573 5612 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.99 0.906 – 1.08 0.814 553 5338 exclusion phecode
575 Other biliary tract disease Digestive 0.98 0.929 – 1.03 0.452 1526 14861 exclusion phecode
575.1 Cholangitis Digestive 0.966 0.846 – 1.1 0.612 249 2393 exclusion phecode
575.2 Obstruction of bile duct Digestive 0.952 0.86 – 1.05 0.347 430 4062 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 1.07 0.905 – 1.26 0.433 141 1406 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.01 0.927 – 1.09 0.898 642 6256 exclusion phecode
575.8 Other disorders of biliary tract Digestive 0.947 0.88 – 1.02 0.139 809 7757 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.12 0.951 – 1.33 0.169 144 1474 exclusion phecode
577 Diseases of pancreas Digestive 0.987 0.935 – 1.04 0.637 1452 14290 exclusion phecode
577.1 Acute pancreatitis Digestive 0.999 0.929 – 1.08 0.984 792 7752 exclusion phecode
577.2 Chronic pancreatitis Digestive 0.927 0.828 – 1.04 0.189 328 3134 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.979 0.877 – 1.09 0.702 357 3438 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.968 – 1.05 0.745 2805 24846 exclusion phecode
578.1 Hematemesis Digestive 0.939 0.836 – 1.06 0.294 317 3058 exclusion phecode
578.2 Blood in stool Digestive 1 0.954 – 1.05 0.913 1695 16887 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 0.99 0.936 – 1.05 0.737 1344 13940 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.974 0.91 – 1.04 0.447 925 9438 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.986 0.949 – 1.02 0.478 2986 23337 exclusion phecode
579.2 Splenomegaly Digestive 0.918 0.835 – 1.01 0.0782 478 4839 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.933 0.864 – 1.01 0.0753 734 7627 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.932 0.872 – 0.997 0.0396 963 9947 exclusion phecode
580.1 Glomerulonephritis Genitourinary 0.962 0.847 – 1.09 0.546 249 2650 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.984 0.795 – 1.22 0.879 88 957 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1 0.79 – 1.28 0.969 72 759 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.954 0.82 – 1.11 0.547 176 1864 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.09 0.91 – 1.3 0.361 129 1395 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.928 0.859 – 1 0.062 706 7449 exclusion phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 0.895 0.807 – 0.993 0.0355 412 4326 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.997 0.898 – 1.11 0.962 376 3995 exclusion phecode
580.4 Renal sclerosis, NOS Genitourinary 1.04 0.905 – 1.2 0.561 222 2182 exclusion phecode
585 Renal failure Genitourinary 0.974 0.942 – 1.01 0.122 4397 22315 exclusion phecode
585.1 Acute renal failure Genitourinary 0.977 0.936 – 1.02 0.277 2487 18216 exclusion phecode
585.2 Renal failure NOS Genitourinary 0.988 0.903 – 1.08 0.793 517 5252 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.977 0.94 – 1.02 0.237 3190 19818 exclusion phecode
585.31 Renal dialysis Genitourinary 0.982 0.887 – 1.09 0.723 408 4392 exclusion phecode
585.32 End stage renal disease Genitourinary 0.982 0.902 – 1.07 0.68 579 6187 exclusion phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 0.993 0.943 – 1.05 0.781 1672 13142 exclusion phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.01 0.92 – 1.1 0.896 524 5327 exclusion phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 0.98 0.902 – 1.06 0.631 614 6285 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 0.992 0.961 – 1.02 0.63 4826 23731 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.02 0.896 – 1.16 0.754 247 2327 exclusion phecode
586.11 Small kidney Genitourinary 1.06 0.889 – 1.27 0.507 142 1325 exclusion phecode
586.12 Vesicoureteral reflux Genitourinary 0.927 0.76 – 1.13 0.454 103 964 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.05 0.978 – 1.13 0.174 836 8276 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.981 0.809 – 1.19 0.848 117 1149 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.02 0.962 – 1.08 0.51 1269 11522 exclusion phecode
587 Kidney replaced by transpant Genitourinary 0.965 0.874 – 1.07 0.485 427 4997 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 0.978 0.892 – 1.07 0.633 518 5553 exclusion phecode
588.1 Renal osteodystrophy Genitourinary 1.06 0.895 – 1.25 0.512 150 1875 exclusion phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.02 0.916 – 1.13 0.757 401 4156 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.03 0.949 – 1.12 0.469 628 6447 exclusion phecode
590 Pyelonephritis Genitourinary 1 0.939 – 1.07 0.918 952 9402 exclusion phecode
591 Urinary tract infection Genitourinary 0.966 0.939 – 0.994 0.0175 6485 22138 exclusion phecode
592 Cystitis and urethritis Genitourinary 0.978 0.931 – 1.03 0.374 1820 15606 exclusion phecode
592.1 Cystitis Genitourinary 0.974 0.927 – 1.02 0.306 1723 14844 exclusion phecode
592.11 Acute cystitis Genitourinary 0.957 0.896 – 1.02 0.186 996 9497 exclusion phecode
592.12 Chronic cystitis Genitourinary 1.03 0.875 – 1.22 0.704 151 1510 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.06 0.944 – 1.19 0.318 306 2985 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.992 0.821 – 1.2 0.935 122 1236 exclusion phecode
593 Hematuria Genitourinary 0.955 0.919 – 0.993 0.0204 2990 21456 exclusion phecode
593.1 Gross hematuria Genitourinary 0.899 0.838 – 0.964 0.00273 900 8466 exclusion phecode
593.2 Microscopic hematuria Genitourinary 1.01 0.927 – 1.1 0.816 568 5662 exclusion phecode
594 Urinary calculus Genitourinary 1.02 0.983 – 1.05 0.358 4533 25909 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.01 0.982 – 1.05 0.376 4263 25784 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.05 0.917 – 1.19 0.504 250 2306 exclusion phecode
594.3 Calculus of ureter Genitourinary 0.965 0.902 – 1.03 0.302 925 8775 exclusion phecode
594.8 Renal colic Genitourinary 0.984 0.864 – 1.12 0.809 245 2390 exclusion phecode
595 Hydronephrosis Genitourinary 0.969 0.912 – 1.03 0.305 1168 11064 exclusion phecode
596 Other disorders of bladder Genitourinary 1 0.958 – 1.05 0.908 2032 18154 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 0.905 0.792 – 1.03 0.141 248 2302 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 0.959 0.901 – 1.02 0.192 1100 10675 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.967 0.901 – 1.04 0.35 859 7836 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.954 0.869 – 1.05 0.317 493 4481 exclusion phecode
597.2 Urinary complications NEC Genitourinary 0.968 0.894 – 1.05 0.413 681 6552 exclusion phecode
597.8 Urethral hypermobility/ISD Genitourinary 0.981 0.827 – 1.16 0.826 145 1249 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.01 0.95 – 1.08 0.671 975 9779 exclusion phecode
598.4 Other cells and casts in urine Genitourinary 1.07 0.829 – 1.38 0.606 63 689 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.01 0.949 – 1.08 0.687 957 9561 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.975 0.951 – 1 0.0479 9242 20709 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.947 0.856 – 1.05 0.29 430 4023 exclusion phecode
599.2 Retention of urine Genitourinary 0.995 0.958 – 1.03 0.79 3298 19454 exclusion phecode
599.3 Dysuria Genitourinary 0.957 0.919 – 0.997 0.0349 2762 18700 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.987 0.952 – 1.02 0.482 3703 18053 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 0.97 0.935 – 1.01 0.107 3410 19151 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.07 0.961 – 1.19 0.22 396 3788 exclusion phecode
599.7 Urethral discharge Genitourinary 1.25 0.971 – 1.62 0.0831 67 620 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 0.959 0.924 – 0.995 0.0254 3493 18691 exclusion phecode
599.9 Other abnormality of urination Genitourinary 0.976 0.93 – 1.02 0.329 1848 15977 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.951 0.904 – 1 0.053 2302 7240 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 0.938 0.863 – 1.02 0.134 620 5942 exclusion phecode
601.1 Prostatitis Genitourinary 1.01 0.888 – 1.14 0.916 261 2714 exclusion phecode
601.11 Acute prostatitis Genitourinary 1.07 0.835 – 1.36 0.606 69 705 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1.04 0.797 – 1.35 0.779 57 545 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.946 0.829 – 1.08 0.407 242 2424 exclusion phecode
601.4 Balanoposthitis Genitourinary 0.883 0.702 – 1.11 0.289 81 728 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.802 0.642 – 1 0.0517 92 929 exclusion phecode
602 Other disorders of prostate Genitourinary 0.807 0.691 – 0.943 0.00693 189 1849 exclusion phecode
603 Other disorders of testis Genitourinary 0.928 0.818 – 1.05 0.24 279 2680 exclusion phecode
603.1 Hydrocele Genitourinary 0.915 0.783 – 1.07 0.264 181 1681 exclusion phecode
603.2 Spermatocele Genitourinary 0.964 0.781 – 1.19 0.737 98 985 exclusion phecode
604 Disorders of penis Genitourinary 0.896 0.811 – 0.99 0.0307 443 4105 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.785 0.642 – 0.96 0.0185 108 931 exclusion phecode
604.3 Peyronie's disease Genitourinary 0.926 0.78 – 1.1 0.374 148 1310 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.94 0.896 – 0.987 0.0123 2213 8264 exclusion phecode
608 Other disorders of male genital organs Genitourinary 0.961 0.9 – 1.03 0.23 1015 9120 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.08 0.962 – 1.22 0.187 296 2913 exclusion phecode
609.1 Infertility, male Genitourinary 1.04 0.907 – 1.2 0.557 222 2172 exclusion phecode
609.11 Azoospermia and oligospermia Genitourinary 1.08 0.848 – 1.37 0.543 74 716 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 1.2 0.976 – 1.49 0.0836 98 964 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.94 0.9 – 0.982 0.00542 2494 11879 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.911 0.855 – 0.971 0.00423 1055 10065 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.934 0.89 – 0.98 0.00513 1982 11801 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.948 0.882 – 1.02 0.15 813 8495 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.941 0.907 – 0.975 0.000949 3981 13087 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.94 0.904 – 0.978 0.00232 3259 11438 exclusion phecode
611.11 Mammographic microcalcification Genitourinary 0.922 0.855 – 0.994 0.0343 747 7446 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.953 0.912 – 0.996 0.0307 2405 13050 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.911 0.845 – 0.983 0.0162 750 7547 exclusion phecode
612.1 Galactorrhea Genitourinary 0.94 0.766 – 1.15 0.555 96 978 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.9 0.826 – 0.98 0.016 577 5691 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 0.85 0.643 – 1.12 0.253 53 599 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.961 0.922 – 1 0.0642 2580 15302 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.05 0.949 – 1.16 0.356 425 4317 exclusion phecode
613.5 Mastodynia Genitourinary 0.943 0.885 – 1 0.0698 1061 10902 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.91 0.835 – 0.99 0.0286 593 5993 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 0.983 0.908 – 1.06 0.674 661 6760 exclusion phecode
613.9 Breast disorder NOS Genitourinary 0.968 0.906 – 1.03 0.337 955 9778 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.982 0.941 – 1.02 0.405 2578 13626 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.921 0.808 – 1.05 0.22 241 2282 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.907 0.814 – 1.01 0.0767 364 3472 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.754 0.583 – 0.975 0.0314 65 649 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.978 0.825 – 1.16 0.801 150 1424 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.983 0.844 – 1.14 0.826 174 1722 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.07 0.883 – 1.28 0.51 120 1151 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.981 0.937 – 1.03 0.412 2177 13520 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.04 0.892 – 1.21 0.617 181 1699 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.966 0.92 – 1.01 0.162 1876 13224 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.725 0.582 – 0.905 0.00436 88 895 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 1 0.841 – 1.2 0.962 135 1380 exclusion phecode
615 Endometriosis Genitourinary 1.03 0.972 – 1.1 0.298 1143 10485 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 0.97 0.914 – 1.03 0.314 1227 11655 exclusion phecode
618 Genital prolapse Genitourinary 0.989 0.937 – 1.04 0.695 1446 12001 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.992 0.929 – 1.06 0.803 987 8946 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.05 0.947 – 1.17 0.333 356 3498 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.953 0.833 – 1.09 0.485 240 2214 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.928 0.827 – 1.04 0.201 321 2998 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 0.963 0.929 – 0.999 0.0413 3949 13008 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.981 0.922 – 1.04 0.55 1125 9718 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 0.981 0.884 – 1.09 0.716 379 3832 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.927 0.83 – 1.03 0.175 346 3354 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.962 0.913 – 1.01 0.146 1621 12665 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.922 0.853 – 0.996 0.0403 715 7624 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 0.969 0.854 – 1.1 0.63 266 2835 exclusion phecode
620.1 Dysplasia of cervix Genitourinary 0.9 0.745 – 1.09 0.273 128 1287 exclusion phecode
621 Endometrial hyperplasia Genitourinary 1.03 0.913 – 1.16 0.64 289 2764 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.922 0.863 – 0.985 0.0154 993 9816 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.926 0.861 – 0.996 0.0384 807 7846 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 0.903 0.797 – 1.02 0.108 270 2916 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 0.968 0.882 – 1.06 0.496 480 5085 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.941 0.877 – 1.01 0.0952 871 8341 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 1.07 0.89 – 1.27 0.49 131 1359 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.986 0.932 – 1.04 0.631 1344 10615 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.925 0.892 – 0.959 2.84e-05 3985 11987 exclusion phecode
625.1 Dyspareunia Genitourinary 0.942 0.878 – 1.01 0.0909 892 8688 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.953 0.919 – 0.988 0.00987 4208 10905 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.939 0.901 – 0.979 0.00281 3080 10275 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.901 0.834 – 0.975 0.00912 735 6185 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 0.924 0.875 – 0.977 0.00517 1546 8556 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.968 0.914 – 1.02 0.26 1378 8841 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.944 0.874 – 1.02 0.149 710 6524 exclusion phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.902 0.797 – 1.02 0.0993 284 2705 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.9 0.842 – 0.962 0.00186 1032 7297 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.903 0.791 – 1.03 0.133 250 2399 exclusion phecode
626.8 Infertility, female Genitourinary 0.98 0.898 – 1.07 0.648 581 4649 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.944 0.905 – 0.983 0.0059 2947 10140 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 0.894 0.83 – 0.964 0.0035 751 6969 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.931 0.887 – 0.978 0.00453 1951 9547 exclusion phecode
627.21 Symptomatic artificial menopause Genitourinary 0.94 0.771 – 1.15 0.544 102 1040 exclusion phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 1.09 0.949 – 1.24 0.233 227 2331 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.946 0.868 – 1.03 0.201 567 5755 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 0.895 0.791 – 1.01 0.0804 270 2580 exclusion phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.874 0.757 – 1.01 0.0678 206 2030 exclusion phecode
628 Ovarian cyst Genitourinary 0.959 0.907 – 1.01 0.148 1421 9809 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.973 0.893 – 1.06 0.533 590 5778 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.898 0.775 – 1.04 0.15 196 1918 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.934 0.742 – 1.18 0.564 83 863 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.03 0.93 – 1.15 0.548 387 3769 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.05 0.923 – 1.2 0.455 252 2513 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.995 0.861 – 1.15 0.945 198 1917 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.947 0.878 – 1.02 0.158 805 5870 exclusion phecode
636.1 Threatened premature labor Pregnancy Complications 1.01 0.889 – 1.14 0.924 281 2761 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.875 0.761 – 1.01 0.0612 223 2154 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.873 0.778 – 0.979 0.0203 337 3266 exclusion phecode
636.8 Cervical incompetence Pregnancy Complications 1.09 0.83 – 1.44 0.526 53 556 exclusion phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.11 0.877 – 1.39 0.395 75 761 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 0.972 0.9 – 1.05 0.47 769 5405 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.85 0.764 – 0.944 0.00248 390 3872 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.9 0.776 – 1.04 0.163 197 1977 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.983 0.84 – 1.15 0.83 168 1686 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.908 0.724 – 1.14 0.402 82 800 exclusion phecode
644 Anemia during pregnancy Pregnancy Complications 1.01 0.857 – 1.19 0.889 145 1448 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.943 0.831 – 1.07 0.366 269 2656 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.921 0.845 – 1 0.0613 598 4700 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.01 0.846 – 1.2 0.95 138 1408 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.895 0.766 – 1.04 0.16 173 1698 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.95 0.885 – 1.02 0.153 917 5877 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.92 0.824 – 1.03 0.136 377 3709 exclusion phecode
650 Normal delivery Pregnancy Complications 0.966 0.893 – 1.05 0.396 708 5900 exclusion phecode
651 Multiple gestation Pregnancy Complications 0.975 0.791 – 1.2 0.812 95 899 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1.04 0.943 – 1.15 0.424 435 4199 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.946 0.853 – 1.05 0.287 414 3880 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 0.959 0.867 – 1.06 0.409 437 4340 exclusion phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.935 0.84 – 1.04 0.216 375 3690 exclusion phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 1.03 0.874 – 1.22 0.702 151 1490 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.997 0.936 – 1.06 0.917 1153 7368 exclusion phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 0.952 0.859 – 1.05 0.341 424 4054 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.984 0.854 – 1.13 0.821 212 2123 exclusion phecode
658
Maternal complication of pregnancy affecting
Maternal complication of pregnancy affecting fetus or newborn
 Pregnancy Complications 0.837 0.714 – 0.981 0.0284 174 1743 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 1.02 0.929 – 1.13 0.634 474 4363 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.933 0.84 – 1.04 0.195 399 3801 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.881 0.813 – 0.955 0.002 697 5644 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.931 0.856 – 1.01 0.0965 635 4864 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.928 0.783 – 1.1 0.394 147 1501 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.933 0.795 – 1.1 0.4 168 1670 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.847 0.697 – 1.03 0.0922 112 1137 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 0.956 0.924 – 0.989 0.0097 3880 26400 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.886 0.817 – 0.962 0.00371 651 7020 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.959 0.88 – 1.05 0.347 561 6409 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.937 0.881 – 0.997 0.0399 1124 12221 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.923 0.869 – 0.979 0.00807 1230 13076 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.926 0.865 – 0.991 0.0264 949 10252 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 0.97 0.909 – 1.04 0.365 986 10126 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 0.965 0.909 – 1.02 0.234 1226 13494 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.08 0.964 – 1.21 0.183 311 3256 exclusion phecode
686.2 Impetigo Dermatologic 0.86 0.75 – 0.987 0.0313 214 2529 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.05 0.859 – 1.3 0.611 102 1058 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 0.846 0.682 – 1.05 0.128 86 992 exclusion phecode
687 Symptoms affecting skin Dermatologic 0.97 0.939 – 1 0.0727 4397 21707 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.956 0.924 – 0.989 0.00872 4088 21633 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 0.972 0.939 – 1.01 0.105 3821 21680 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.964 0.838 – 1.11 0.614 210 2372 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 0.991 0.958 – 1.03 0.618 4026 21396 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.979 0.947 – 1.01 0.211 4072 27107 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.979 0.935 – 1.02 0.363 2028 21797 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.979 0.936 – 1.03 0.376 2022 21760 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.915 0.815 – 1.03 0.131 306 3530 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.99 0.92 – 1.07 0.798 757 10738 exclusion phecode
694.1 Vitiligo Dermatologic 0.799 0.622 – 1.03 0.0794 69 779 exclusion phecode
694.2 Other dyschromia Dermatologic 1 0.925 – 1.08 0.978 658 9570 exclusion phecode
695 Erythematous conditions Dermatologic 0.971 0.929 – 1.01 0.19 2240 20601 exclusion phecode
695.3 Rosacea Dermatologic 0.955 0.891 – 1.02 0.194 883 11592 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1 0.911 – 1.1 0.957 456 4801 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.878 0.742 – 1.04 0.129 160 1718 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.01 0.914 – 1.11 0.869 436 4561 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 0.902 0.802 – 1.02 0.0871 294 3528 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 0.97 0.879 – 1.07 0.549 443 5124 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 0.966 0.87 – 1.07 0.518 379 4201 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.862 0.803 – 0.927 5.3e-05 830 9102 exclusion phecode
696.3 Pityriasis Dermatologic 0.858 0.652 – 1.13 0.275 56 588 exclusion phecode
696.4 Psoriasis Dermatologic 0.856 0.795 – 0.922 4.15e-05 774 8496 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.863 0.798 – 0.933 0.000227 696 7687 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.889 0.762 – 1.04 0.136 181 1889 exclusion phecode
697 Sarcoidosis Dermatologic 0.923 0.805 – 1.06 0.253 216 2190 exclusion phecode
698 Pruritus and related conditions Dermatologic 1.01 0.956 – 1.07 0.693 1317 13733 exclusion phecode
700 Corns and callosities Dermatologic 0.934 0.855 – 1.02 0.127 541 6053 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.956 0.925 – 0.989 0.00938 3997 26737 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.994 0.873 – 1.13 0.932 245 3062 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.02 0.951 – 1.09 0.621 910 14175 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.983 0.88 – 1.1 0.767 337 3619 exclusion phecode
701.4 Keloid scar Dermatologic 0.913 0.804 – 1.04 0.161 265 3889 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 0.939 0.823 – 1.07 0.35 243 2695 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.99 0.951 – 1.03 0.607 2811 21209 exclusion phecode
702.1 Actinic keratosis Dermatologic 1.04 0.986 – 1.1 0.144 1341 18242 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.978 0.936 – 1.02 0.325 2193 21984 exclusion phecode
703 Diseases of nail, NOS Dermatologic 0.942 0.873 – 1.02 0.122 713 8103 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.924 0.839 – 1.02 0.108 449 4724 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.937 0.891 – 0.986 0.0121 1678 19020 exclusion phecode
704.1 Alopecia Dermatologic 0.945 0.879 – 1.02 0.12 839 8933 exclusion phecode
704.2 Hirsutism Dermatologic 1.04 0.896 – 1.2 0.627 199 2005 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.928 0.866 – 0.995 0.0356 880 10631 exclusion phecode
705 Disorders of sweat glands Dermatologic 1.01 0.912 – 1.13 0.793 376 3862 exclusion phecode
705.1 Dyshidrosis Dermatologic 1.1 0.895 – 1.34 0.375 96 979 exclusion phecode
705.3 Hidradenitis Dermatologic 0.971 0.827 – 1.14 0.723 161 1620 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.01 0.931 – 1.09 0.85 662 7051 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 0.983 0.947 – 1.02 0.364 3194 27202 exclusion phecode
706.1 Acne Dermatologic 0.96 0.91 – 1.01 0.131 1505 15228 exclusion phecode
706.2 Sebaceous cyst Dermatologic 0.977 0.926 – 1.03 0.398 1494 17235 exclusion phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 1.03 0.946 – 1.11 0.542 627 8588 exclusion phecode
707 Chronic ulcer of skin Dermatologic 0.975 0.927 – 1.03 0.329 1686 17088 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1 0.911 – 1.11 0.936 459 4608 exclusion phecode
707.2 Chronic ulcer of leg or foot Dermatologic 0.955 0.874 – 1.04 0.314 535 5520 exclusion phecode
707.3 Chronic ulcer of unspecified site Dermatologic 0.984 0.922 – 1.05 0.616 1031 10607 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.954 0.891 – 1.02 0.185 890 9208 exclusion phecode
709.2 Sicca syndrome Dermatologic 0.996 0.885 – 1.12 0.943 295 3100 exclusion phecode
709.3 Systemic sclerosis Dermatologic 0.976 0.828 – 1.15 0.774 153 1564 exclusion phecode
709.5 Dermatomyositis Dermatologic 0.916 0.703 – 1.19 0.516 60 581 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.04 0.818 – 1.32 0.752 69 690 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.945 0.865 – 1.03 0.213 540 5606 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.939 0.872 – 1.01 0.1 756 7527 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 0.939 0.87 – 1.01 0.106 725 7198 exclusion phecode
710.11 Acute osteomyelitis Musculoskeletal 0.916 0.818 – 1.03 0.13 332 3333 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.06 0.946 – 1.2 0.297 306 3032 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.941 0.871 – 1.02 0.128 694 6832 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 1.11 0.976 – 1.26 0.114 252 2476 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.15 0.983 – 1.33 0.0821 179 1739 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 0.952 0.782 – 1.16 0.623 109 1088 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.946 0.808 – 1.11 0.488 175 1819 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 0.893 0.718 – 1.11 0.311 87 938 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.982 0.926 – 1.04 0.526 1298 11664 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.976 0.916 – 1.04 0.459 1061 9725 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.941 0.873 – 1.01 0.109 782 7617 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.913 0.782 – 1.07 0.253 176 1720 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.895 0.756 – 1.06 0.199 152 1391 exclusion phecode
716 Other arthropathies Musculoskeletal 1.01 0.98 – 1.03 0.668 8492 21537 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.08 0.907 – 1.3 0.375 125 1232 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.06 0.865 – 1.3 0.57 98 891 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1 0.978 – 1.03 0.755 8437 21528 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.825 0.697 – 0.977 0.0256 149 1411 exclusion phecode
720 Spinal stenosis Musculoskeletal 0.97 0.93 – 1.01 0.143 2595 19001 exclusion phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 0.977 0.931 – 1.03 0.342 1892 15772 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 0.974 0.94 – 1.01 0.146 3576 21679 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.974 0.939 – 1.01 0.17 3327 21275 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.963 0.886 – 1.05 0.38 613 5671 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 1.05 0.896 – 1.23 0.537 176 1613 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 0.98 0.948 – 1.01 0.23 4238 23310 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.989 0.949 – 1.03 0.6 2501 21680 exclusion phecode
722.3 Schmorl's nodes Musculoskeletal 1.03 0.842 – 1.26 0.784 99 905 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.982 0.943 – 1.02 0.391 2664 20862 exclusion phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 0.999 0.899 – 1.11 0.985 386 3655 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 0.981 0.866 – 1.11 0.764 279 2650 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.999 0.944 – 1.06 0.974 1299 12558 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 0.979 0.9 – 1.07 0.629 586 6086 exclusion phecode
723.1 Torticollis Musculoskeletal 1.13 0.948 – 1.35 0.172 128 1510 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 0.975 0.937 – 1.02 0.222 2751 21688 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 0.958 0.908 – 1.01 0.117 1471 14276 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.819 0.721 – 0.93 0.00202 265 2718 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 0.998 0.92 – 1.08 0.953 644 6005 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 0.973 0.912 – 1.04 0.415 1024 9770 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.969 0.941 – 0.997 0.0292 6229 20818 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.963 0.932 – 0.994 0.0205 4707 20816 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.964 0.887 – 1.05 0.385 626 6195 exclusion phecode
726.3 Bursitis Musculoskeletal 0.997 0.935 – 1.06 0.921 1069 10468 exclusion phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.964 0.892 – 1.04 0.35 711 7074 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.974 0.943 – 1.01 0.113 4678 20821 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.98 0.934 – 1.03 0.405 1912 16738 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.929 0.818 – 1.06 0.258 266 2630 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.996 0.929 – 1.07 0.898 880 8927 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.878 0.778 – 0.991 0.0345 298 2956 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.94 0.891 – 0.992 0.0254 1509 14121 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.02 0.925 – 1.13 0.667 429 4389 exclusion phecode
727.8 Plica syndrome Musculoskeletal 1.03 0.844 – 1.26 0.772 105 1005 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.998 0.959 – 1.04 0.937 2740 20328 exclusion phecode
728.1 Muscular calcification and ossification Musculoskeletal 0.952 0.729 – 1.24 0.717 57 566 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.986 0.843 – 1.15 0.862 176 1862 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.934 0.887 – 0.983 0.00946 1623 15306 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.952 0.834 – 1.09 0.474 233 2368 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 0.97 0.925 – 1.02 0.198 1971 18249 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.09 0.839 – 1.41 0.528 58 503 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.841 0.663 – 1.07 0.153 78 823 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1 0.823 – 1.22 0.969 105 1108 exclusion phecode
732 Osteochondropathies Musculoskeletal 1.05 0.923 – 1.19 0.471 267 2548 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.15 0.969 – 1.37 0.109 141 1364 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.937 0.728 – 1.21 0.612 68 631 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.968 0.929 – 1.01 0.122 2663 17865 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.07 0.895 – 1.29 0.443 135 1332 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.901 0.8 – 1.01 0.0843 296 3311 exclusion phecode
733.6 Costochondritis Musculoskeletal 0.88 0.769 – 1.01 0.0647 231 2344 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.979 0.902 – 1.06 0.622 622 5905 exclusion phecode
733.9 Chondromalacia Musculoskeletal 0.831 0.656 – 1.05 0.124 75 729 exclusion phecode
735 Acquired foot deformities Musculoskeletal 0.986 0.94 – 1.03 0.549 1934 18729 exclusion phecode
735.1 Flat foot Musculoskeletal 1.02 0.918 – 1.14 0.666 345 3499 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 0.993 0.916 – 1.08 0.86 648 6747 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.957 0.86 – 1.07 0.423 373 3873 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 1.05 0.915 – 1.2 0.491 223 2380 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.968 0.902 – 1.04 0.36 853 8390 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 0.969 0.92 – 1.02 0.221 1626 15961 exclusion phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.883 0.701 – 1.11 0.291 75 721 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 0.898 0.752 – 1.07 0.235 132 1399 exclusion phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.898 0.776 – 1.04 0.147 193 1885 exclusion phecode
736.5 Acquired deformities of knee Musculoskeletal 0.948 0.801 – 1.12 0.532 148 1472 exclusion phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.979 0.85 – 1.13 0.767 210 2078 exclusion phecode
737 Curvature of spine Musculoskeletal 1.01 0.95 – 1.08 0.703 1058 10165 exclusion phecode
737.1 Kyphosis (acquired) Musculoskeletal 1.04 0.928 – 1.16 0.501 325 3000 exclusion phecode
737.2 Lordosis (acquired) Musculoskeletal 0.905 0.69 – 1.19 0.472 58 522 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.996 0.927 – 1.07 0.909 828 7913 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.981 0.93 – 1.03 0.482 1489 15815 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.947 0.877 – 1.02 0.169 721 6667 exclusion phecode
739 Contracture of joint Musculoskeletal 0.99 0.898 – 1.09 0.844 445 4265 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1 0.977 – 1.03 0.886 10234 20995 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.02 0.984 – 1.05 0.309 4198 18641 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.01 0.975 – 1.05 0.549 3574 17426 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.97 0.878 – 1.07 0.543 437 4123 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.03 0.966 – 1.11 0.327 928 7502 exclusion phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 1.09 0.953 – 1.24 0.216 241 2234 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.01 0.98 – 1.03 0.689 9826 20877 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.977 0.949 – 1.01 0.126 5420 24320 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 1.01 0.87 – 1.18 0.857 182 1772 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 0.938 0.871 – 1.01 0.0864 761 8113 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.949 0.898 – 1 0.0625 1405 13681 exclusion phecode
741.4 Joint effusions Musculoskeletal 0.995 0.945 – 1.05 0.859 1557 15663 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.06 0.802 – 1.39 0.699 54 527 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.991 0.953 – 1.03 0.651 2937 22790 exclusion phecode
742.1 Loose body in joint Musculoskeletal 0.91 0.747 – 1.11 0.345 115 1130 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.978 0.852 – 1.12 0.75 223 2161 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.05 0.9 – 1.22 0.538 175 1646 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.992 0.953 – 1.03 0.71 2712 22209 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.971 0.942 – 1 0.0511 5787 25151 exclusion phecode
743.1 Osteoporosis Musculoskeletal 0.982 0.937 – 1.03 0.442 2198 12488 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 0.981 0.936 – 1.03 0.425 2170 12323 exclusion phecode
743.12 Senile osteoporosis Musculoskeletal 0.973 0.866 – 1.09 0.639 324 3290 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 0.915 0.779 – 1.07 0.279 166 1832 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.03 0.955 – 1.12 0.401 658 6667 exclusion phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 0.995 0.885 – 1.12 0.929 296 2882 exclusion phecode
743.22 Pathologic fracture of femur Musculoskeletal 1.03 0.839 – 1.26 0.791 92 912 exclusion phecode
743.4 Stress fracture Musculoskeletal 0.965 0.844 – 1.1 0.603 236 2415 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.956 0.925 – 0.988 0.00784 4392 24225 exclusion phecode
745 Pain in joint Musculoskeletal 0.981 0.959 – 1 0.0892 13092 18162 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.998 0.945 – 1.05 0.955 1460 14314 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.997 0.939 – 1.06 0.926 1172 11324 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1.02 0.927 – 1.13 0.639 431 4224 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.02 0.93 – 1.12 0.689 501 4763 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.951 0.838 – 1.08 0.432 265 2634 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.957 0.854 – 1.07 0.45 322 3314 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.755 0.595 – 0.958 0.0208 77 747 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.01 0.906 – 1.12 0.902 383 3850 exclusion phecode
749.1 Cleft palate Congenital Anomalies 1.05 0.816 – 1.36 0.695 72 707 exclusion phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.976 0.776 – 1.23 0.836 83 801 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.978 0.899 – 1.06 0.606 592 6023 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.03 0.905 – 1.18 0.623 239 2417 exclusion phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 1.01 0.785 – 1.29 0.966 73 750 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.06 0.813 – 1.37 0.679 62 656 exclusion phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 1.11 0.892 – 1.38 0.35 89 925 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.959 0.861 – 1.07 0.448 357 3654 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.08 0.938 – 1.24 0.295 215 2168 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.825 0.69 – 0.986 0.0342 145 1516 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.972 0.919 – 1.03 0.311 1386 13731 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.878 0.795 – 0.969 0.00961 449 4231 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.899 0.798 – 1.01 0.0778 304 2878 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.752 0.618 – 0.915 0.00446 118 1089 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.984 0.918 – 1.05 0.641 893 8968 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.954 0.877 – 1.04 0.268 604 6145 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.98 0.852 – 1.13 0.776 215 2038 exclusion phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.1 0.931 – 1.3 0.261 142 1332 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.981 0.91 – 1.06 0.615 766 7293 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 0.967 0.889 – 1.05 0.44 619 5781 exclusion phecode
752.11 Spina bifida Congenital Anomalies 1.04 0.869 – 1.25 0.65 127 1283 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.981 0.833 – 1.16 0.817 168 1721 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.813 0.67 – 0.985 0.035 112 1171 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.942 0.877 – 1.01 0.106 841 7851 exclusion phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 0.985 0.795 – 1.22 0.894 96 942 exclusion phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 0.983 0.885 – 1.09 0.75 395 3603 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.97 0.889 – 1.06 0.503 554 5344 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.993 0.876 – 1.13 0.917 278 2639 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.02 0.89 – 1.16 0.807 234 2277 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.1 0.924 – 1.3 0.289 142 1359 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.942 0.877 – 1.01 0.0968 843 8532 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.937 0.812 – 1.08 0.367 209 2027 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.964 0.886 – 1.05 0.39 597 6054 exclusion phecode
757 Congenital anomalies of the integument Congenital Anomalies 0.937 0.786 – 1.12 0.473 126 2274 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.848 0.704 – 1.02 0.0835 121 1170 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.806 0.644 – 1.01 0.0583 82 796 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.923 0.835 – 1.02 0.118 415 4296 exclusion phecode
760 Back pain Symptoms 0.982 0.959 – 1.01 0.146 10360 20893 exclusion phecode
761 Cervicalgia Symptoms 0.984 0.952 – 1.02 0.334 4166 26711 exclusion phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 0.965 0.925 – 1.01 0.106 2370 21803 exclusion phecode
764 Sciatica Symptoms 0.936 0.895 – 0.98 0.00451 2078 20088 exclusion phecode
765 Cervical radiculitis Symptoms 1.03 0.968 – 1.09 0.365 1167 11259 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.994 0.958 – 1.03 0.732 3283 25135 exclusion phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.24 0.986 – 1.56 0.0656 71 671 exclusion phecode
769 Nonallopathic lesions NEC Symptoms 0.947 0.878 – 1.02 0.156 736 7448 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 0.984 0.95 – 1.02 0.38 3552 22569 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.988 0.95 – 1.03 0.559 2800 24357 exclusion phecode
771.1 Swelling of limb Symptoms 0.976 0.941 – 1.01 0.179 3447 24490 exclusion phecode
771.2 Cramp of limb Symptoms 1.04 0.953 – 1.13 0.398 600 6210 exclusion phecode
772 Symptoms of the muscles Symptoms 0.949 0.895 – 1.01 0.0842 1235 12369 exclusion phecode
772.1 Muscular wasting and disuse atrophy Symptoms 1.07 0.948 – 1.22 0.262 270 2664 exclusion phecode
772.2 Spasm of muscle Symptoms 0.991 0.939 – 1.05 0.731 1475 14832 exclusion phecode
772.3 Muscle weakness Symptoms 0.96 0.915 – 1.01 0.0967 1828 17947 exclusion phecode
772.4 Rhabdomyolysis Symptoms 1.05 0.856 – 1.3 0.628 98 935 exclusion phecode
772.6 Facial weakness Symptoms 0.967 0.855 – 1.09 0.595 282 2887 exclusion phecode
773 Pain in limb Symptoms 0.97 0.946 – 0.994 0.014 9334 21919 exclusion phecode
780 Hypothermia/Chills Symptoms 1.07 0.933 – 1.23 0.333 225 2461 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.973 0.919 – 1.03 0.336 1346 13276 exclusion phecode
781.1 Loss of height Symptoms 1.18 0.912 – 1.52 0.209 63 622 exclusion phecode
782.3 Edema Symptoms 0.978 0.944 – 1.01 0.234 3480 25028 exclusion phecode
782.6 Pallor and flushing Symptoms 1.03 0.948 – 1.13 0.447 554 5715 exclusion phecode
783 Fever of unknown origin Symptoms 0.978 0.945 – 1.01 0.212 3640 27585 exclusion phecode
783.1 Postprocedural fever Symptoms 0.999 0.866 – 1.15 0.989 202 2016 exclusion phecode
785 Abdominal pain Symptoms 0.995 0.972 – 1.02 0.661 10999 20258 exclusion phecode
788 Syncope and collapse Symptoms 0.98 0.94 – 1.02 0.358 2378 23349 exclusion phecode
789 Nausea and vomiting Symptoms 0.996 0.969 – 1.02 0.76 6899 24342 exclusion phecode
789.1 Persistent vomiting Symptoms 0.996 0.911 – 1.09 0.933 543 5238 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 0.961 0.908 – 1.02 0.178 1307 13557 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.05 0.874 – 1.26 0.609 128 1274 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 0.973 0.94 – 1.01 0.128 3694 25789 exclusion phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.14 0.974 – 1.33 0.105 175 1662 exclusion phecode
790.9 Abnormal arterial blood gases Symptoms 0.889 0.723 – 1.09 0.267 97 968 exclusion phecode
791 Gangrene Symptoms 1.08 0.917 – 1.27 0.357 155 1660 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.953 0.907 – 1 0.0595 1863 10208 exclusion phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Symptoms 0.919 0.85 – 0.993 0.0329 726 6896 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.04 0.943 – 1.14 0.462 466 4832 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 0.974 0.918 – 1.03 0.379 1207 12942 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.928 0.81 – 1.06 0.281 220 3423 exclusion phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 0.986 0.932 – 1.04 0.619 1352 13210 exclusion phecode
795.8 Abnormal tumor markers Symptoms 0.963 0.907 – 1.02 0.207 1268 10149 exclusion phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 1.1 0.918 – 1.33 0.294 126 1334 exclusion phecode
796 Elevated prostate specific antigen [PSA] Symptoms 0.934 0.877 – 0.995 0.0342 1235 6218 exclusion phecode
797 Shock Symptoms 0.897 0.803 – 1 0.0543 353 3435 exclusion phecode
797.1 Cardiogenic shock Symptoms 0.903 0.761 – 1.07 0.245 150 1422 exclusion phecode
798 Malaise and fatigue Symptoms 0.958 0.932 – 0.984 0.00194 6939 24306 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 0.949 0.89 – 1.01 0.107 1052 10944 exclusion phecode
799 Debility unspecified Symptoms 0.97 0.914 – 1.03 0.313 1216 12176 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 0.977 0.927 – 1.03 0.385 1532 15289 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.945 0.84 – 1.06 0.344 304 3064 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.998 0.902 – 1.1 0.963 418 4182 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.02 0.941 – 1.11 0.62 625 6172 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.99 0.864 – 1.13 0.883 238 2387 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.01 0.956 – 1.06 0.76 1496 14909 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.01 0.938 – 1.09 0.79 774 7566 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.02 0.897 – 1.15 0.789 261 2580 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 1.02 0.966 – 1.08 0.463 1369 13406 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1.03 0.935 – 1.13 0.583 487 4828 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1 0.929 – 1.08 0.968 746 7441 exclusion phecode
803.21 Colles' fracture Injuries & Poisonings 0.992 0.855 – 1.15 0.911 200 2003 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.06 0.944 – 1.18 0.34 337 3490 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 1.05 0.982 – 1.11 0.167 1084 10471 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.983 0.917 – 1.05 0.639 849 8380 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 0.972 0.881 – 1.07 0.582 417 4234 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.996 0.951 – 1.04 0.862 2047 19059 exclusion phecode
817 Concussion Injuries & Poisonings 1.02 0.941 – 1.1 0.634 671 6576 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.931 0.8 – 1.08 0.35 186 1871 exclusion phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.766 0.578 – 1.01 0.063 56 561 exclusion phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 0.865 0.671 – 1.11 0.261 71 682 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.999 0.947 – 1.05 0.968 1513 14774 exclusion phecode
830 Dislocation Injuries & Poisonings 1.01 0.966 – 1.05 0.774 2657 23623 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 1.02 0.963 – 1.07 0.57 1514 14564 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 1.02 0.915 – 1.13 0.738 356 3373 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.982 0.952 – 1.01 0.234 5158 25560 exclusion phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.967 0.864 – 1.08 0.561 326 3243 exclusion phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.951 0.893 – 1.01 0.126 1057 10370 exclusion phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.955 0.911 – 1 0.0545 2008 16594 exclusion phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.956 0.895 – 1.02 0.18 984 9776 exclusion phecode
842 Other sprains and strains Injuries & Poisonings 0.984 0.918 – 1.05 0.651 887 8913 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.962 0.909 – 1.02 0.181 1319 14258 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.973 0.89 – 1.06 0.539 542 6434 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.09 0.973 – 1.22 0.139 343 3161 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1 0.944 – 1.06 0.977 1245 11953 exclusion phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1 0.87 – 1.15 0.996 219 2076 exclusion phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.09 0.94 – 1.25 0.265 209 1984 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.06 0.991 – 1.13 0.0929 1028 9573 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1 0.952 – 1.05 0.939 1641 15417 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 0.938 0.889 – 0.989 0.019 1472 14692 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 0.969 0.772 – 1.22 0.787 85 996 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.936 0.897 – 0.977 0.00263 2304 25315 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.949 0.781 – 1.15 0.595 105 1266 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1.09 0.85 – 1.4 0.5 67 909 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.97 0.893 – 1.05 0.47 623 8549 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.929 0.718 – 1.2 0.573 61 1345 exclusion phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 0.89 0.758 – 1.04 0.152 162 1824 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.975 0.77 – 1.23 0.831 77 1416 exclusion phecode
870.8 Open wound of genital organs Injuries & Poisonings 0.767 0.612 – 0.96 0.0208 86 998 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 0.94 0.897 – 0.985 0.00982 1964 21951 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.959 0.86 – 1.07 0.453 356 3664 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.926 0.851 – 1.01 0.0741 590 6172 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.09 0.957 – 1.25 0.189 237 2756 exclusion phecode
871.4 Open wound of toe(s) Injuries & Poisonings 0.922 0.778 – 1.09 0.346 145 1561 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 0.999 0.888 – 1.12 0.989 309 3384 exclusion phecode
873 Broken tooth Injuries & Poisonings 0.988 0.821 – 1.19 0.896 122 1252 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.12 0.909 – 1.38 0.286 97 985 exclusion phecode
875 Non-healing surgical wound Injuries & Poisonings 0.988 0.884 – 1.1 0.826 338 4045 exclusion phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 0.977 0.891 – 1.07 0.63 503 5451 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 0.989 0.917 – 1.07 0.773 749 7277 exclusion phecode
910 Superficial injury, infected Injuries & Poisonings 0.886 0.697 – 1.13 0.325 73 732 exclusion phecode
911 Blister Injuries & Poisonings 1.1 0.928 – 1.31 0.264 142 1426 exclusion phecode
912 Insect bite Injuries & Poisonings 0.932 0.816 – 1.06 0.294 238 2625 exclusion phecode
913 Toxic effect of venom Injuries & Poisonings 1.06 0.917 – 1.23 0.416 194 2027 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 0.982 0.935 – 1.03 0.447 1839 18942 exclusion phecode
916 Contusion Injuries & Poisonings 0.987 0.947 – 1.03 0.55 2508 24512 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.993 0.905 – 1.09 0.874 500 5160 exclusion phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Injuries & Poisonings 0.972 0.88 – 1.07 0.574 435 4549 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.988 0.944 – 1.03 0.601 2060 20402 exclusion phecode
938.1 Acute dermatitis due to solar radiation Injuries & Poisonings 1.05 0.867 – 1.27 0.627 107 1375 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.989 0.944 – 1.04 0.644 1924 20023 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.961 0.928 – 0.995 0.0246 3794 23225 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.08 0.898 – 1.31 0.401 119 1186 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.918 0.785 – 1.07 0.285 167 1857 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1 0.891 – 1.13 0.938 299 3279 exclusion phecode
947 Urticaria Injuries & Poisonings 0.972 0.9 – 1.05 0.473 718 7664 exclusion phecode
949 Allergies, other Injuries & Poisonings 0.946 0.914 – 0.978 0.00114 4184 22749 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.948 0.85 – 1.06 0.338 359 3443 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.02 0.825 – 1.25 0.886 95 970 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.02 0.947 – 1.09 0.647 860 8623 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 0.983 0.814 – 1.19 0.861 112 1012 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.895 0.717 – 1.12 0.329 82 741 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1 0.951 – 1.05 0.993 1675 15093 exclusion phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 0.945 0.783 – 1.14 0.56 116 1272 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1 0.941 – 1.06 0.989 1133 11137 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 0.972 0.876 – 1.08 0.598 371 3834 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.992 0.92 – 1.07 0.843 746 7239 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.909 0.822 – 1.01 0.0625 416 4532 exclusion phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 0.893 0.783 – 1.02 0.0894 242 2480 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 0.874 0.76 – 1.01 0.0592 213 2454 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.97 0.92 – 1.02 0.264 1499 16030 exclusion phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 0.978 0.927 – 1.03 0.421 1461 15698 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.988 0.89 – 1.1 0.82 403 4053 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.01 0.904 – 1.12 0.926 381 3822 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.985 0.907 – 1.07 0.723 633 6100 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.978 0.919 – 1.04 0.492 1062 10360 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.829 0.655 – 1.05 0.12 84 788 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.943 0.742 – 1.2 0.636 71 693 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.927 0.86 – 1 0.0497 751 8121 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 0.946 0.816 – 1.1 0.457 200 1971 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.1 0.938 – 1.28 0.248 167 1682 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.11 0.879 – 1.41 0.376 65 647 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.959 0.753 – 1.22 0.736 70 678 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.992 0.76 – 1.29 0.95 57 572 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.986 0.93 – 1.05 0.642 1233 11859 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 0.971 0.922 – 1.02 0.254 1621 16570 exclusion phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 0.959 0.896 – 1.03 0.22 937 9070 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.82 0.635 – 1.06 0.126 71 713 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 0.973 0.926 – 1.02 0.265 1769 18809 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 0.954 0.901 – 1.01 0.105 1345 13355 exclusion phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 0.885 0.763 – 1.03 0.108 194 2011 exclusion phecode
994.2 Sepsis Injuries & Poisonings 0.964 0.909 – 1.02 0.215 1274 12662 exclusion phecode
994.21 Septic shock Injuries & Poisonings 0.939 0.845 – 1.04 0.246 383 3717 exclusion phecode
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