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Scores Breast cancer [female] UK Biobank (UKB) PheWAS analysis

Breast cancer [female] — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID prsweb-phecode174-1-icogs-er-negative-brca-p-5e-08-ukb-20200608Legacy P_5e-08GWAS HitsMichailidou K et al. 2018

Evaluation cohort: UK Biobank (UKB).

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137 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1 0.98 – 1.02 0.844 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 0.968 0.931 – 1.01 0.113 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.968 0.892 – 1.05 0.43 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 1.06 0.992 – 1.14 0.081 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.16 0.893 – 1.52 0.262 55 550 all phecode
010 Tuberculosis Infectious Diseases 1.04 0.883 – 1.22 0.664 166 1659 all phecode
038 Septicemia Infectious Diseases 1.02 0.992 – 1.06 0.148 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.01 0.937 – 1.08 0.873 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 0.923 0.84 – 1.01 0.092 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 1.01 0.989 – 1.03 0.449 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 1 0.965 – 1.04 0.942 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 0.988 0.939 – 1.04 0.639 1641 16433 all phecode
041.4 E. coli Infectious Diseases 1.01 0.972 – 1.05 0.568 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 1.08 0.977 – 1.2 0.129 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.13 0.917 – 1.39 0.254 95 949 all phecode
054 Herpes simplex Infectious Diseases 1.03 0.897 – 1.18 0.672 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 0.92 0.843 – 1 0.0597 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 1 0.778 – 1.3 0.978 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 0.941 0.781 – 1.13 0.522 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 0.887 0.778 – 1.01 0.0737 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.13 1 – 1.28 0.0425 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.02 0.927 – 1.13 0.653 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.999 0.84 – 1.19 0.99 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.896 0.736 – 1.09 0.275 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 0.976 0.914 – 1.04 0.462 1004 10036 all phecode
079 Viral infection Infectious Diseases 1.04 0.997 – 1.08 0.0716 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 1.19 0.924 – 1.52 0.181 64 640 all phecode
080 Postoperative infection Infectious Diseases 1.01 0.977 – 1.04 0.639 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 0.994 0.954 – 1.04 0.773 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.04 0.818 – 1.32 0.756 71 709 all phecode
1000 Burns Injuries & Poisonings 1.04 0.954 – 1.13 0.398 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 0.988 0.931 – 1.05 0.688 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 0.992 0.965 – 1.02 0.577 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 0.938 0.833 – 1.06 0.291 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 1.02 0.969 – 1.08 0.427 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 0.988 0.87 – 1.12 0.85 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 1.09 0.952 – 1.24 0.218 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.04 0.98 – 1.11 0.183 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 1.01 0.986 – 1.03 0.472 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 1.01 0.984 – 1.04 0.459 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.987 0.966 – 1.01 0.226 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 0.942 0.769 – 1.16 0.568 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.08 0.968 – 1.22 0.161 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.09 0.854 – 1.4 0.483 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 0.995 0.964 – 1.03 0.75 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.01 0.996 – 1.03 0.128 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.933 0.825 – 1.06 0.273 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 0.913 0.805 – 1.04 0.156 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.756 0.592 – 0.966 0.0254 74 756 all phecode
110.12 Althete's foot Infectious Diseases 0.776 0.649 – 0.927 0.0052 141 1410 all phecode
112 Candidiasis Infectious Diseases 0.966 0.924 – 1.01 0.133 2126 21275 all phecode
117 Mycoses Infectious Diseases 0.955 0.842 – 1.08 0.478 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 0.97 0.826 – 1.14 0.712 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 1.04 0.827 – 1.31 0.739 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 0.907 0.72 – 1.14 0.406 69 689 all phecode
134 Helminthiases Infectious Diseases 1.04 0.871 – 1.25 0.643 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 0.989 0.811 – 1.21 0.911 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.04 0.908 – 1.2 0.549 205 2050 all phecode
145 Cancer of mouth Neoplasms 1.02 0.945 – 1.11 0.562 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 1.05 0.936 – 1.18 0.4 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 0.952 0.782 – 1.16 0.628 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.33 1.03 – 1.7 0.0261 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.04 0.96 – 1.13 0.325 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 1 0.88 – 1.14 0.978 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 1.12 0.984 – 1.27 0.0856 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.861 0.665 – 1.11 0.254 57 570 all phecode
150 Cancer of esophagus Neoplasms 1.08 1 – 1.16 0.0404 762 7630 all phecode
151 Cancer of stomach Neoplasms 1.03 0.943 – 1.12 0.543 569 5696 all phecode
153 Colorectal cancer Neoplasms 1.01 0.978 – 1.04 0.609 4580 45799 all phecode
153.2 Colon cancer Neoplasms 1.03 0.997 – 1.07 0.0749 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.974 0.932 – 1.02 0.249 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.968 0.875 – 1.07 0.536 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.893 0.76 – 1.05 0.172 158 1580 all phecode
157 Pancreatic cancer Neoplasms 1.03 0.946 – 1.11 0.544 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.962 0.902 – 1.03 0.234 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.02 0.995 – 1.05 0.103 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.989 0.853 – 1.15 0.879 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.03 0.897 – 1.19 0.644 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.18 1.03 – 1.36 0.02 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 1.02 0.789 – 1.31 0.896 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 0.971 0.934 – 1.01 0.141 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 0.959 0.918 – 1 0.0611 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 1 0.91 – 1.11 0.934 437 4364 all phecode
170.1 Bone cancer Neoplasms 1.06 0.891 – 1.27 0.491 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 1.04 0.925 – 1.16 0.547 331 3303 all phecode
172 Skin cancer Neoplasms 0.986 0.969 – 1 0.13 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.06 1.01 – 1.1 0.00714 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 1.06 1.02 – 1.1 0.00469 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.976 0.957 – 0.995 0.0145 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.02 0.945 – 1.11 0.575 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.05 0.912 – 1.21 0.484 181 1818 all phecode
174 Breast cancer Neoplasms 1.18 1.16 – 1.2 2.29e-70 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 1.18 1.16 – 1.2 7.27e-70 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.18 1.16 – 1.2 1.12e-66 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.15 0.951 – 1.38 0.154 115 1148 all phecode
175 Acquired absence of breast Neoplasms 1.17 1.12 – 1.22 2.35e-13 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 0.991 0.947 – 1.04 0.682 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 1.02 0.904 – 1.16 0.718 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.01 0.964 – 1.06 0.709 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 1.02 0.965 – 1.08 0.462 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 1.07 1.02 – 1.13 0.012 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.11 1.04 – 1.19 0.00139 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.11 1.03 – 1.18 0.00298 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.03 0.916 – 1.16 0.622 305 3049 all phecode
185 Cancer of prostate Neoplasms 0.915 0.89 – 0.94 7.47e-11 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 0.966 0.877 – 1.07 0.491 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.826 0.643 – 1.06 0.135 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 1.01 0.894 – 1.14 0.887 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.918 0.755 – 1.12 0.391 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.95 0.92 – 0.981 0.00179 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.971 0.912 – 1.03 0.359 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.968 0.908 – 1.03 0.32 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.09 0.857 – 1.4 0.471 66 660 all phecode
189.2 Cancer of bladder Neoplasms 0.93 0.892 – 0.971 0.000886 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.933 0.892 – 0.975 0.00234 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.839 0.706 – 0.998 0.0476 144 1439 all phecode
190 Cancer of eye Neoplasms 1.14 0.982 – 1.33 0.0843 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.06 0.977 – 1.14 0.169 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1.04 0.952 – 1.13 0.394 566 5650 all phecode
191.11 Cancer of brain Neoplasms 1.04 0.955 – 1.14 0.339 525 5240 all phecode
193 Thyroid cancer Neoplasms 0.9 0.805 – 1.01 0.0638 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 1 0.816 – 1.23 0.974 95 949 all phecode
195 Cancer, suspected or other Neoplasms 1 0.986 – 1.02 0.816 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 1 0.986 – 1.02 0.756 16267 159497 all phecode
197 Chemotherapy Neoplasms 1.05 1.03 – 1.06 2.89e-10 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 1.06 1.04 – 1.08 1.64e-08 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.09 1.06 – 1.12 2.76e-09 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.04 1 – 1.09 0.0486 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.06 1.01 – 1.12 0.025 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.07 1.02 – 1.11 0.00163 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.08 1.01 – 1.16 0.0255 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.01 0.963 – 1.05 0.775 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.896 0.77 – 1.04 0.153 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 0.976 0.925 – 1.03 0.387 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 0.912 0.747 – 1.11 0.369 95 950 all phecode
200 Myeloproliferative disease Neoplasms 0.995 0.932 – 1.06 0.878 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 0.931 0.837 – 1.04 0.189 387 3867 all phecode
201 Hodgkin's disease Neoplasms 0.985 0.87 – 1.12 0.808 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.982 0.941 – 1.03 0.414 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.985 0.939 – 1.03 0.552 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 0.995 0.893 – 1.11 0.931 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 0.932 0.856 – 1.01 0.104 581 5824 all phecode
204 Leukemia Neoplasms 1.04 0.985 – 1.09 0.172 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 1.08 0.989 – 1.17 0.0865 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.1 0.838 – 1.44 0.501 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.06 0.963 – 1.16 0.248 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 0.971 0.883 – 1.07 0.544 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.95 0.849 – 1.06 0.378 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.02 0.864 – 1.2 0.814 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 1.06 0.972 – 1.15 0.188 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 0.976 0.962 – 0.991 0.00149 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.992 0.928 – 1.06 0.811 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.996 0.968 – 1.02 0.781 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.07 0.963 – 1.2 0.2 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.935 0.833 – 1.05 0.256 318 3187 all phecode
214 Lipoma Neoplasms 1 0.974 – 1.03 0.995 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1 0.97 – 1.03 0.99 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.01 0.947 – 1.07 0.829 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 1.01 0.984 – 1.03 0.539 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.07 0.984 – 1.16 0.117 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.08 0.99 – 1.17 0.0851 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 1.02 0.999 – 1.04 0.0666 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 1.02 1 – 1.04 0.0249 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.911 0.817 – 1.02 0.0933 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 1.02 0.97 – 1.08 0.4 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.04 0.906 – 1.19 0.593 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 1.06 0.902 – 1.25 0.478 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.888 0.757 – 1.04 0.147 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 0.925 0.77 – 1.11 0.405 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.909 0.71 – 1.16 0.452 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.07 0.993 – 1.15 0.0782 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.06 0.988 – 1.14 0.101 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.04 0.808 – 1.34 0.761 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.12 0.987 – 1.27 0.0785 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.996 0.928 – 1.07 0.91 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.916 0.788 – 1.06 0.25 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.925 0.831 – 1.03 0.157 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.11 0.991 – 1.25 0.0702 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1 0.954 – 1.06 0.857 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.03 0.986 – 1.07 0.199 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.02 0.939 – 1.11 0.619 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.999 0.939 – 1.06 0.983 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.01 0.92 – 1.12 0.787 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.991 0.916 – 1.07 0.83 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.989 0.943 – 1.04 0.643 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 0.983 0.892 – 1.08 0.727 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.14 0.923 – 1.4 0.229 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.01 0.85 – 1.2 0.897 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 1.01 0.99 – 1.02 0.434 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.01 0.953 – 1.08 0.658 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.923 0.752 – 1.13 0.442 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.01 0.991 – 1.03 0.354 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 0.98 0.868 – 1.11 0.749 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.95 0.828 – 1.09 0.467 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.937 0.814 – 1.08 0.361 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 0.989 0.893 – 1.1 0.834 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 0.991 0.976 – 1.01 0.209 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.04 0.996 – 1.08 0.0748 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.07 0.937 – 1.21 0.334 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.24 0.994 – 1.55 0.0563 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.07 0.975 – 1.17 0.158 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.14 0.969 – 1.34 0.116 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.985 0.97 – 1 0.0551 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.989 0.81 – 1.21 0.911 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.08 0.934 – 1.24 0.307 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.04 0.976 – 1.11 0.22 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.04 0.953 – 1.14 0.358 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1 0.924 – 1.08 0.999 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.944 0.831 – 1.07 0.373 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.04 0.943 – 1.15 0.411 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.01 0.845 – 1.2 0.922 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.06 0.948 – 1.18 0.323 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.04 0.986 – 1.1 0.138 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 0.955 0.893 – 1.02 0.177 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.983 0.917 – 1.05 0.636 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.966 0.898 – 1.04 0.358 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.02 0.858 – 1.21 0.833 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.989 0.914 – 1.07 0.779 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.991 0.854 – 1.15 0.906 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.839 0.68 – 1.04 0.104 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.05 0.928 – 1.19 0.429 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.825 0.663 – 1.03 0.0831 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.954 0.808 – 1.13 0.582 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.972 0.896 – 1.05 0.493 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.945 0.811 – 1.1 0.467 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.955 0.783 – 1.16 0.648 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.961 0.759 – 1.22 0.742 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.03 0.92 – 1.14 0.646 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.03 0.927 – 1.15 0.555 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.05 0.917 – 1.19 0.502 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.06 0.925 – 1.22 0.386 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 1.16 0.99 – 1.37 0.066 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.17 0.988 – 1.37 0.0685 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.03 0.835 – 1.27 0.791 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 1 0.845 – 1.19 0.963 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.02 0.88 – 1.18 0.803 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 0.79 0.593 – 1.05 0.107 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 0.976 0.908 – 1.05 0.5 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 0.967 0.911 – 1.03 0.264 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.987 0.916 – 1.06 0.723 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.933 0.847 – 1.03 0.158 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.04 0.833 – 1.3 0.723 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.992 0.87 – 1.13 0.907 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 1.11 0.987 – 1.24 0.0815 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.03 0.912 – 1.15 0.669 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.03 0.906 – 1.17 0.668 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.04 0.896 – 1.21 0.6 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.05 0.87 – 1.27 0.601 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.04 0.823 – 1.32 0.723 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.975 0.829 – 1.15 0.76 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.939 0.788 – 1.12 0.482 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.998 0.987 – 1.01 0.766 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.998 0.987 – 1.01 0.75 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.997 0.985 – 1.01 0.598 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.09 0.838 – 1.42 0.52 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.05 0.894 – 1.22 0.574 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.06 0.916 – 1.22 0.457 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.988 0.955 – 1.02 0.49 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 0.988 0.952 – 1.02 0.515 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.08 0.892 – 1.31 0.423 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.987 0.908 – 1.07 0.755 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.984 0.902 – 1.07 0.725 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.01 0.965 – 1.06 0.682 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 1.03 0.95 – 1.11 0.487 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.02 0.922 – 1.14 0.658 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1 0.942 – 1.06 0.994 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.959 0.818 – 1.12 0.6 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.02 0.999 – 1.05 0.06 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.03 0.995 – 1.06 0.0985 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.03 0.904 – 1.17 0.667 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.03 0.984 – 1.08 0.195 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.07 0.999 – 1.14 0.0537 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.03 0.971 – 1.08 0.369 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.03 0.971 – 1.1 0.315 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 1.03 0.966 – 1.1 0.377 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 1 0.825 – 1.22 0.981 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.03 0.987 – 1.07 0.197 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 1.02 0.926 – 1.12 0.691 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 1.09 0.912 – 1.3 0.343 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 0.982 0.917 – 1.05 0.607 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.1 0.985 – 1.22 0.0922 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.08 0.944 – 1.23 0.266 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.07 0.814 – 1.42 0.613 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.975 0.955 – 0.994 0.0109 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 0.976 0.957 – 0.996 0.0175 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 0.887 0.706 – 1.11 0.301 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.733 0.566 – 0.95 0.0187 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.888 0.776 – 1.02 0.082 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 0.879 0.759 – 1.02 0.0847 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.882 0.738 – 1.05 0.168 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 0.934 0.82 – 1.06 0.304 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 0.992 0.969 – 1.02 0.501 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.99 0.966 – 1.01 0.399 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.04 0.95 – 1.15 0.37 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 0.995 0.936 – 1.06 0.868 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 0.99 0.931 – 1.05 0.757 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 1 0.932 – 1.08 0.917 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.924 0.792 – 1.08 0.314 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 0.939 0.809 – 1.09 0.407 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 1.06 0.814 – 1.38 0.661 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.08 0.912 – 1.27 0.383 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.08 0.83 – 1.41 0.564 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.952 0.759 – 1.19 0.672 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.08 0.908 – 1.29 0.38 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.1 0.898 – 1.34 0.359 103 1059 all phecode
284 Aplastic anemia Hematopoietic 0.974 0.883 – 1.08 0.603 435 4357 all phecode
285 Other anemias Hematopoietic 0.996 0.978 – 1.01 0.689 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.908 0.8 – 1.03 0.137 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.06 0.977 – 1.14 0.173 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.05 0.954 – 1.16 0.303 414 4147 all phecode
286 Coagulation defects Hematopoietic 1.08 1.01 – 1.16 0.0232 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 1.03 0.932 – 1.13 0.601 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 0.887 0.718 – 1.1 0.265 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.07 0.949 – 1.21 0.267 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.18 0.898 – 1.54 0.238 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.29 1.03 – 1.6 0.0233 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.16 1.04 – 1.29 0.00704 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.99 0.941 – 1.04 0.693 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.899 0.748 – 1.08 0.254 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 0.951 0.713 – 1.27 0.73 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 1 0.949 – 1.05 1 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1 0.907 – 1.11 0.936 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.06 0.839 – 1.34 0.628 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 1.04 1.01 – 1.08 0.0153 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 1.05 1.02 – 1.09 0.00398 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 1.05 1.02 – 1.09 0.00389 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 1.12 0.885 – 1.42 0.343 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.981 0.914 – 1.05 0.599 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.893 0.791 – 1.01 0.0658 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 1.03 0.993 – 1.08 0.102 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 0.957 0.873 – 1.05 0.343 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 0.954 0.844 – 1.08 0.456 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.02 0.826 – 1.27 0.837 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.02 0.971 – 1.07 0.464 1929 19281 all phecode
290.1 Dementias Mental Disorders 0.999 0.937 – 1.07 0.984 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 0.977 0.885 – 1.08 0.652 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 0.904 0.78 – 1.05 0.18 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.04 0.965 – 1.13 0.279 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.996 0.784 – 1.27 0.975 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.938 0.874 – 1.01 0.0781 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.05 0.878 – 1.26 0.579 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.938 0.831 – 1.06 0.302 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 0.916 0.83 – 1.01 0.0794 436 4376 all phecode
292 Neurological disorders Mental Disorders 1.02 0.991 – 1.05 0.163 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.993 0.942 – 1.05 0.793 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.904 0.778 – 1.05 0.189 190 1907 all phecode
292.3 Memory loss Mental Disorders 1.05 0.971 – 1.13 0.223 696 6978 all phecode
292.4 Altered mental status Mental Disorders 1.04 0.994 – 1.09 0.0925 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 1.04 0.926 – 1.17 0.515 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 1.01 0.966 – 1.06 0.656 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.985 0.92 – 1.05 0.673 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.09 1.01 – 1.17 0.0177 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 1.05 0.965 – 1.14 0.252 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 1.19 1.03 – 1.38 0.0196 178 1780 all phecode
295.3 Psychosis Mental Disorders 1.13 0.971 – 1.32 0.112 169 1710 all phecode
296 Mood disorders Mental Disorders 0.99 0.972 – 1.01 0.283 12372 123822 all phecode
296.1 Bipolar Mental Disorders 1 0.939 – 1.07 0.986 1059 10599 all phecode
296.2 Depression Mental Disorders 0.988 0.969 – 1.01 0.207 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 0.95 0.853 – 1.06 0.356 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.908 0.808 – 1.02 0.106 311 3070 all phecode
300 Anxiety disorders Mental Disorders 1.01 0.988 – 1.04 0.333 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 1.01 0.989 – 1.04 0.26 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1.06 0.895 – 1.25 0.505 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.999 0.924 – 1.08 0.984 707 7065 all phecode
300.13 Phobia Mental Disorders 0.947 0.863 – 1.04 0.25 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.994 0.832 – 1.19 0.947 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 0.988 0.761 – 1.28 0.929 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 1.01 0.845 – 1.2 0.929 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.02 0.853 – 1.23 0.793 113 1129 all phecode
301 Personality disorders Mental Disorders 1.06 0.952 – 1.19 0.275 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.972 0.805 – 1.17 0.766 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.943 0.833 – 1.07 0.356 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.977 0.888 – 1.08 0.642 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 0.933 0.836 – 1.04 0.22 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 1.21 1.01 – 1.46 0.0427 123 1229 all phecode
304 Adjustment reaction Mental Disorders 1.09 0.972 – 1.23 0.137 293 2936 all phecode
305.2 Eating disorder Mental Disorders 0.969 0.783 – 1.2 0.772 90 900 all phecode
306 Other mental disorder Mental Disorders 1 0.99 – 1.02 0.665 28056 230087 all phecode
306.9 Tension headache Mental Disorders 1.01 0.904 – 1.14 0.821 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 0.873 0.695 – 1.1 0.24 76 770 all phecode
313.3 Autism Mental Disorders 0.838 0.638 – 1.1 0.205 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 0.995 0.893 – 1.11 0.922 351 3517 all phecode
315.1 Learning disorder Mental Disorders 1.23 1.05 – 1.44 0.00964 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 0.982 0.796 – 1.21 0.865 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 0.999 0.971 – 1.03 0.959 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.01 0.76 – 1.33 0.961 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 1 0.984 – 1.02 0.819 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 1.01 0.988 – 1.03 0.375 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.06 0.988 – 1.14 0.102 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 1 0.986 – 1.02 0.926 19359 185465 all phecode
320 Meningitis Neurological 1.08 0.984 – 1.19 0.103 444 4447 all phecode
323 Encephalitis Neurological 1.05 0.941 – 1.17 0.375 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 0.895 0.699 – 1.15 0.381 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.02 0.901 – 1.15 0.792 292 2916 all phecode
327 Sleep disorders Neurological 1 0.941 – 1.06 0.999 1164 11659 all phecode
327.3 Sleep apnea Neurological 1 0.974 – 1.04 0.78 4428 44318 all phecode
327.4 Insomnia Neurological 0.973 0.828 – 1.14 0.741 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 0.967 0.811 – 1.15 0.713 136 1390 all phecode
331 Other cerebral degenerations Neurological 1.05 0.99 – 1.12 0.104 1142 11416 all phecode
331.1 Hydrocephalus Neurological 0.978 0.892 – 1.07 0.632 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 1.12 1.02 – 1.24 0.0204 430 4298 all phecode
332 Parkinson's disease Neurological 1.01 0.953 – 1.08 0.691 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.972 0.907 – 1.04 0.409 894 8954 all phecode
333.1 Essential tremor Neurological 1.03 0.896 – 1.18 0.681 216 2157 all phecode
333.2 Myoclonus Neurological 0.865 0.702 – 1.07 0.176 96 958 all phecode
333.4 Torsion dystonia Neurological 0.928 0.816 – 1.06 0.257 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 1.06 1.01 – 1.11 0.0272 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 0.944 0.784 – 1.14 0.543 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 1.08 0.953 – 1.23 0.22 245 2446 all phecode
335 Multiple sclerosis Neurological 1 0.946 – 1.06 0.969 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 1.06 0.931 – 1.2 0.398 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 0.983 0.772 – 1.25 0.889 72 719 all phecode
338 Pain Neurological 1.03 0.959 – 1.11 0.405 768 7692 all phecode
338.1 Acute pain Neurological 1.02 0.923 – 1.13 0.686 394 3937 all phecode
338.2 Chronic pain Neurological 1.02 0.915 – 1.13 0.765 380 3817 all phecode
339 Other headache syndromes Neurological 1.02 0.994 – 1.04 0.156 7819 78241 all phecode
340 Migraine Neurological 1.01 0.977 – 1.05 0.454 2860 28602 all phecode
340.1 Migrain with aura Neurological 1.2 1.04 – 1.37 0.0107 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.987 0.867 – 1.12 0.844 252 2535 all phecode
342 Hemiplegia Neurological 0.954 0.905 – 1.01 0.0805 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 1 0.849 – 1.18 0.982 145 1450 all phecode
344 Other paralytic syndromes Neurological 0.96 0.886 – 1.04 0.317 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.01 0.985 – 1.04 0.363 5023 50270 all phecode
345.1 Epilepsy Neurological 1.03 0.959 – 1.1 0.43 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 1.12 1.02 – 1.24 0.0197 439 4385 all phecode
345.12 Partial epilepsy Neurological 1.04 0.919 – 1.18 0.536 277 2776 all phecode
345.3 Convulsions Neurological 0.988 0.946 – 1.03 0.6 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.27 1.07 – 1.51 0.00579 144 1438 all phecode
348 Other conditions of brain Neurological 1.05 0.973 – 1.13 0.215 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 0.995 0.875 – 1.13 0.944 268 2678 all phecode
348.4 Cerebral cysts Neurological 1.14 0.963 – 1.36 0.125 133 1350 all phecode
348.7 Coma Neurological 0.945 0.846 – 1.05 0.313 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.03 0.911 – 1.17 0.608 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 0.992 0.894 – 1.1 0.885 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.13 1.01 – 1.26 0.0334 342 3414 all phecode
350 Abnormal movement Neurological 1.03 0.993 – 1.07 0.111 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 1.07 0.996 – 1.14 0.0632 887 8852 all phecode
350.2 Abnormality of gait Neurological 1.03 0.978 – 1.08 0.274 1596 15969 all phecode
350.3 Lack of coordination Neurological 1.01 0.909 – 1.13 0.812 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.926 0.705 – 1.22 0.578 54 540 all phecode
351 Other peripheral nerve disorders Neurological 0.994 0.976 – 1.01 0.5 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 0.994 0.94 – 1.05 0.824 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.01 0.919 – 1.11 0.857 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 0.994 0.927 – 1.07 0.867 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 0.993 0.935 – 1.06 0.824 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 0.952 0.789 – 1.15 0.607 114 1138 all phecode
353.2 Nerve root lesions Neurological 0.893 0.687 – 1.16 0.398 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.07 0.911 – 1.26 0.399 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.01 0.96 – 1.07 0.609 1361 13648 all phecode
358 Myoneural disorders Neurological 1.11 0.966 – 1.27 0.141 211 2109 all phecode
358.1 Myasthenia gravis Neurological 1.06 0.92 – 1.23 0.398 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 1.09 0.989 – 1.19 0.0837 465 4646 all phecode
359.1 Muscular dystrophies Neurological 1.24 1.03 – 1.5 0.0221 122 1219 all phecode
359.2 Myopathy Neurological 1.04 0.939 – 1.16 0.436 360 3597 all phecode
360 Disorders of the globe Sense Organs 0.993 0.887 – 1.11 0.908 337 3367 all phecode
360.2 Progressive myopia Sense Organs 1.08 0.948 – 1.22 0.255 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 1.03 0.995 – 1.07 0.0869 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.03 0.978 – 1.09 0.242 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 1.01 0.795 – 1.28 0.949 68 680 all phecode
362 Other retinal disorders Sense Organs 1 0.972 – 1.04 0.776 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.997 0.954 – 1.04 0.886 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.997 0.954 – 1.04 0.905 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.2 1.03 – 1.41 0.0226 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 1.31 1.07 – 1.6 0.00906 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.03 0.958 – 1.1 0.443 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 1.26 1.08 – 1.46 0.00296 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.936 0.741 – 1.18 0.576 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.745 0.612 – 0.908 0.00351 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.12 0.964 – 1.31 0.137 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 1.08 0.855 – 1.36 0.526 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.927 0.854 – 1.01 0.0705 647 6485 all phecode
364.1 Corneal opacity Sense Organs 1.02 0.82 – 1.28 0.83 90 910 all phecode
364.2 Corneal edema Sense Organs 0.907 0.723 – 1.14 0.4 79 800 all phecode
364.4 Corneal degenerations Sense Organs 0.931 0.804 – 1.08 0.337 201 2017 all phecode
364.41 Keratoconus Sense Organs 0.922 0.738 – 1.15 0.475 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 0.909 0.786 – 1.05 0.198 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.762 0.617 – 0.94 0.0114 100 1000 all phecode
365 Glaucoma Sense Organs 1.03 0.998 – 1.06 0.0664 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 1.04 0.972 – 1.1 0.271 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.03 0.97 – 1.1 0.31 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.06 0.976 – 1.14 0.174 698 6996 all phecode
366 Cataract Sense Organs 1 0.99 – 1.02 0.564 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 1.09 0.855 – 1.39 0.481 69 700 all phecode
366.2 Senile cataract Sense Organs 0.994 0.972 – 1.02 0.629 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 1.01 0.822 – 1.24 0.942 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.03 0.992 – 1.08 0.114 2408 24092 all phecode
367.1 Myopia Sense Organs 1.02 0.961 – 1.08 0.545 1251 12519 all phecode
367.2 Astigmatism Sense Organs 1.18 1.01 – 1.36 0.0311 190 1899 all phecode
367.8 Hypermetropia Sense Organs 0.982 0.862 – 1.12 0.783 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 1.02 0.947 – 1.1 0.571 719 7198 all phecode
368 Visual disturbances Sense Organs 1.01 0.97 – 1.05 0.708 2962 29648 all phecode
368.1 Amblyopia Sense Organs 0.98 0.896 – 1.07 0.653 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.981 0.909 – 1.06 0.621 727 7288 all phecode
368.3 Anisometropia Sense Organs 0.984 0.837 – 1.16 0.842 154 1548 all phecode
368.4 Visual field defects Sense Organs 1.04 0.932 – 1.16 0.482 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 0.997 0.918 – 1.08 0.948 612 6115 all phecode
369 Infection of the eye Sense Organs 0.995 0.91 – 1.09 0.914 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 0.892 0.741 – 1.07 0.225 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 1.01 0.874 – 1.17 0.888 213 2128 all phecode
370 Keratitis Sense Organs 0.978 0.869 – 1.1 0.717 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 0.934 0.791 – 1.1 0.422 141 1408 all phecode
371 Inflammation of the eye Sense Organs 1.03 0.989 – 1.06 0.178 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.05 0.958 – 1.16 0.284 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 1.01 0.971 – 1.06 0.542 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 1.04 0.967 – 1.12 0.282 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 1.01 0.984 – 1.04 0.434 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 0.98 0.92 – 1.04 0.54 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 0.997 0.95 – 1.05 0.918 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 1.03 0.986 – 1.08 0.187 2204 22031 all phecode
375.2 Epiphora Sense Organs 0.968 0.903 – 1.04 0.359 898 8969 all phecode
376 Disorders of the orbit Sense Organs 0.848 0.685 – 1.05 0.13 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.906 0.812 – 1.01 0.0774 361 3618 all phecode
377.1 Optic atrophy Sense Organs 0.978 0.756 – 1.26 0.865 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.966 0.805 – 1.16 0.709 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.01 0.961 – 1.07 0.604 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.01 0.945 – 1.08 0.739 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.957 0.831 – 1.1 0.544 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 1.02 0.901 – 1.15 0.756 275 2755 all phecode
379 Other disorders of eye Sense Organs 0.987 0.954 – 1.02 0.46 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 0.933 0.882 – 0.987 0.0154 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.982 0.935 – 1.03 0.469 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 0.947 0.74 – 1.21 0.667 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.05 0.949 – 1.17 0.337 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.03 0.881 – 1.2 0.711 169 1690 all phecode
380 Disorders of external ear Sense Organs 0.969 0.894 – 1.05 0.455 642 6413 all phecode
380.1 Otitis externa Sense Organs 0.989 0.902 – 1.08 0.814 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 0.993 0.892 – 1.11 0.897 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.996 0.953 – 1.04 0.856 2150 21493 all phecode
381.1 Otitis media Sense Organs 1.01 0.959 – 1.06 0.768 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.989 0.921 – 1.06 0.757 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 1.01 0.876 – 1.17 0.866 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 0.873 0.743 – 1.03 0.101 171 1709 all phecode
381.9 Otorrhea Sense Organs 1.02 0.903 – 1.16 0.725 281 2807 all phecode
382 Otalgia Sense Organs 1 0.89 – 1.13 0.986 308 3084 all phecode
383 Otosclerosis Sense Organs 0.92 0.818 – 1.04 0.166 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 0.969 0.915 – 1.03 0.285 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 0.969 0.908 – 1.03 0.33 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.951 0.884 – 1.02 0.182 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 1.01 0.927 – 1.1 0.856 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.816 0.712 – 0.934 0.00324 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.996 0.947 – 1.05 0.862 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 0.975 0.894 – 1.06 0.564 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 0.942 0.846 – 1.05 0.274 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 1.03 0.956 – 1.11 0.449 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.996 0.966 – 1.03 0.776 4582 45806 all phecode
388 Other disorders of ear Sense Organs 1.04 0.904 – 1.2 0.57 202 2017 all phecode
389 Hearing loss Sense Organs 1 0.971 – 1.03 0.877 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.935 0.849 – 1.03 0.171 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 0.973 0.884 – 1.07 0.585 450 4497 all phecode
389.4 Tinnitus Sense Organs 1.07 0.976 – 1.17 0.151 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.02 0.986 – 1.05 0.31 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 1.03 0.991 – 1.07 0.13 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 1.01 0.953 – 1.07 0.765 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 0.989 0.928 – 1.05 0.735 1058 10566 all phecode
395 Heart valve disorders Circulatory System 1.03 0.996 – 1.06 0.0906 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.02 0.985 – 1.06 0.246 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.968 0.857 – 1.09 0.603 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.05 0.857 – 1.28 0.653 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.903 0.732 – 1.11 0.341 97 970 all phecode
395.6 Heart valve replaced Circulatory System 1.03 0.978 – 1.09 0.259 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 0.988 0.928 – 1.05 0.715 1048 10468 all phecode
401 Hypertension Circulatory System 0.992 0.983 – 1 0.0514 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 0.992 0.983 – 1 0.0487 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.01 0.96 – 1.05 0.788 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 1.08 0.971 – 1.2 0.158 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.987 0.937 – 1.04 0.631 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 1.05 0.892 – 1.24 0.548 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.01 0.961 – 1.07 0.625 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 0.994 0.982 – 1.01 0.322 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.972 0.944 – 1 0.0514 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 0.999 0.981 – 1.02 0.948 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 0.999 0.983 – 1.02 0.927 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 0.993 0.978 – 1.01 0.352 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.961 0.888 – 1.04 0.32 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.992 0.975 – 1.01 0.334 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.93 0.876 – 0.988 0.0183 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 0.98 0.933 – 1.03 0.404 1823 18228 all phecode
414.2 ASCVD Circulatory System 1.07 0.834 – 1.37 0.601 72 719 all phecode
415 Pulmonary heart disease Circulatory System 0.996 0.966 – 1.03 0.79 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.823 0.647 – 1.05 0.113 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.02 0.937 – 1.11 0.671 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.03 0.941 – 1.14 0.481 448 4475 all phecode
416 Cardiomegaly Circulatory System 0.976 0.938 – 1.02 0.238 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 1.01 0.998 – 1.02 0.0951 28599 270106 all phecode
418.1 Precordial pain Circulatory System 0.987 0.953 – 1.02 0.457 3551 35541 all phecode
420 Carditis Circulatory System 0.984 0.94 – 1.03 0.473 2106 21053 all phecode
420.1 Myocarditis Circulatory System 0.918 0.76 – 1.11 0.37 127 1267 all phecode
420.2 Pericarditis Circulatory System 0.993 0.938 – 1.05 0.802 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 1.04 0.907 – 1.2 0.564 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 1.02 0.841 – 1.24 0.822 113 1129 all phecode
420.3 Endocarditis Circulatory System 0.962 0.891 – 1.04 0.32 719 7194 all phecode
425 Cardiomyopathy Circulatory System 1.04 0.984 – 1.1 0.163 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.05 0.986 – 1.11 0.136 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.15 0.964 – 1.37 0.119 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.989 0.842 – 1.16 0.891 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 0.949 0.734 – 1.23 0.688 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 0.991 0.967 – 1.02 0.496 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.02 0.973 – 1.06 0.452 2114 21162 all phecode
426.21 First degree AV block Circulatory System 0.999 0.935 – 1.07 0.975 986 9867 all phecode
426.23 Second degree AV block Circulatory System 1.01 0.913 – 1.11 0.909 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.03 0.945 – 1.12 0.521 587 5868 all phecode
426.25 Other heart block Circulatory System 1.12 0.935 – 1.33 0.224 131 1318 all phecode
426.3 Bundle branch block Circulatory System 1.01 0.978 – 1.05 0.468 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 1.01 0.96 – 1.07 0.669 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 1 0.952 – 1.05 0.993 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.898 0.787 – 1.02 0.111 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 0.953 0.733 – 1.24 0.718 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.992 0.952 – 1.03 0.705 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.997 0.955 – 1.04 0.9 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 0.995 0.982 – 1.01 0.473 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 0.987 0.952 – 1.02 0.481 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.995 0.954 – 1.04 0.824 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.962 0.899 – 1.03 0.264 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 0.991 0.974 – 1.01 0.312 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.996 0.961 – 1.03 0.816 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.975 0.918 – 1.03 0.399 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.994 0.892 – 1.11 0.912 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 0.966 0.904 – 1.03 0.301 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.923 0.863 – 0.987 0.0199 952 9541 all phecode
427.6 Premature beats Circulatory System 0.972 0.89 – 1.06 0.52 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 1.02 0.851 – 1.23 0.806 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 1.02 0.978 – 1.07 0.34 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.977 0.881 – 1.08 0.664 402 4029 all phecode
427.9 Palpitations Circulatory System 1.01 0.98 – 1.05 0.451 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.996 0.969 – 1.02 0.772 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 0.965 0.923 – 1.01 0.122 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 1.01 0.984 – 1.05 0.347 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.06 0.98 – 1.14 0.146 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 1.05 0.821 – 1.35 0.687 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.06 0.968 – 1.16 0.213 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.07 0.923 – 1.23 0.387 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 0.978 0.933 – 1.03 0.365 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.979 0.912 – 1.05 0.556 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 0.934 0.866 – 1.01 0.0739 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 1 0.886 – 1.13 0.978 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 0.976 0.955 – 0.997 0.0289 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.943 0.888 – 1 0.0564 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 0.956 0.834 – 1.1 0.524 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.969 0.939 – 1 0.0496 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.977 0.93 – 1.03 0.373 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 0.982 0.945 – 1.02 0.347 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 0.977 0.935 – 1.02 0.306 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 0.918 0.827 – 1.02 0.108 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.952 0.899 – 1.01 0.0924 1279 12783 all phecode
440 Atherosclerosis Circulatory System 1.03 0.976 – 1.09 0.278 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.928 0.771 – 1.12 0.428 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.04 0.966 – 1.12 0.303 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.07 0.95 – 1.21 0.26 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 0.877 0.807 – 0.954 0.00219 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.855 0.755 – 0.968 0.0137 283 2827 all phecode
442 Other aneurysm Circulatory System 0.976 0.931 – 1.02 0.315 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 0.993 0.941 – 1.05 0.785 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.978 0.914 – 1.05 0.516 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 0.907 0.739 – 1.11 0.349 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.942 0.807 – 1.1 0.443 169 1696 all phecode
442.4 Arterial dissection Circulatory System 1.12 0.851 – 1.48 0.414 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 0.91 0.785 – 1.06 0.213 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 0.996 0.964 – 1.03 0.828 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 1 0.944 – 1.07 0.921 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.967 0.873 – 1.07 0.522 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 0.993 0.96 – 1.03 0.683 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.99 0.951 – 1.03 0.634 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.01 0.944 – 1.08 0.778 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.979 0.898 – 1.07 0.635 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.03 0.963 – 1.11 0.353 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 1.01 0.869 – 1.17 0.899 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 1.06 0.955 – 1.17 0.28 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 1.02 0.897 – 1.17 0.731 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1 0.947 – 1.06 0.965 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 1.03 0.961 – 1.1 0.413 868 8712 all phecode
448 Disease of capillaries Circulatory System 1.04 0.88 – 1.24 0.629 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.02 0.948 – 1.11 0.551 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.997 0.965 – 1.03 0.87 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.995 0.962 – 1.03 0.79 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 1.03 0.946 – 1.12 0.487 564 5645 all phecode
454 Varicose veins Circulatory System 0.998 0.979 – 1.02 0.821 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1 0.983 – 1.02 0.827 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.971 0.894 – 1.05 0.486 624 6325 all phecode
455 Hemorrhoids Circulatory System 0.988 0.975 – 1 0.0855 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.94 0.802 – 1.1 0.442 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.07 0.869 – 1.32 0.52 97 967 all phecode
458 Hypotension Circulatory System 1 0.974 – 1.03 0.95 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 1.04 0.985 – 1.1 0.158 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 0.921 0.804 – 1.05 0.233 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 0.996 0.962 – 1.03 0.81 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 0.993 0.977 – 1.01 0.361 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 0.955 0.801 – 1.14 0.606 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 0.992 0.976 – 1.01 0.356 16103 159422 all phecode
464 Acute sinusitis Respiratory 0.925 0.799 – 1.07 0.299 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.02 0.977 – 1.06 0.359 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 1.02 0.953 – 1.1 0.54 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.05 0.894 – 1.22 0.581 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.01 0.977 – 1.04 0.674 4654 46553 all phecode
471 Nasal polyps Respiratory 0.996 0.961 – 1.03 0.83 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.02 0.958 – 1.09 0.485 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 0.997 0.958 – 1.04 0.893 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 0.928 0.756 – 1.14 0.473 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.958 0.844 – 1.09 0.499 264 2647 all phecode
473.4 Voice disturbance Respiratory 1.03 0.965 – 1.09 0.397 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 0.975 0.928 – 1.02 0.304 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 0.958 0.878 – 1.05 0.338 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.996 0.936 – 1.06 0.888 1122 11199 all phecode
475 Chronic sinusitis Respiratory 1 0.962 – 1.04 0.92 2589 25882 all phecode
476 Allergic rhinitis Respiratory 0.948 0.889 – 1.01 0.103 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 0.999 0.958 – 1.04 0.977 2447 24452 all phecode
478 Throat pain Respiratory 0.94 0.845 – 1.05 0.261 377 3789 all phecode
479 Other upper respiratory disease Respiratory 1.01 0.976 – 1.04 0.619 4074 40737 all phecode
480 Pneumonia Respiratory 1.03 1.01 – 1.05 0.00232 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 1.03 1.01 – 1.06 0.00948 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.03 1 – 1.06 0.0313 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.05 0.849 – 1.29 0.664 93 929 all phecode
480.2 Viral pneumonia Respiratory 0.8 0.624 – 1.03 0.0791 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.06 0.866 – 1.3 0.564 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.02 0.951 – 1.1 0.553 794 7951 all phecode
481 Influenza Respiratory 0.947 0.845 – 1.06 0.344 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.02 0.884 – 1.18 0.762 193 1930 all phecode
495 Asthma Respiratory 0.998 0.986 – 1.01 0.794 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 1.07 0.939 – 1.21 0.321 250 2510 all phecode
496 Chronic airway obstruction Respiratory 1.01 0.991 – 1.03 0.282 10424 101546 all phecode
496.1 Emphysema Respiratory 0.971 0.924 – 1.02 0.243 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 1.06 1.02 – 1.1 0.00207 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.06 1.02 – 1.1 0.00438 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 1 0.955 – 1.05 0.958 1885 18859 all phecode
497 Bronchitis Respiratory 1.06 0.975 – 1.15 0.182 626 6267 all phecode
500 Lung disease due to external agents Respiratory 1.04 0.945 – 1.15 0.396 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.08 0.862 – 1.35 0.507 79 784 all phecode
500.2 Pneumoconiosis Respiratory 1.07 0.939 – 1.22 0.312 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1 0.926 – 1.09 0.939 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.01 0.94 – 1.08 0.865 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 0.954 0.87 – 1.05 0.311 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.974 0.87 – 1.09 0.652 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 0.907 0.698 – 1.18 0.463 61 610 all phecode
506 Empyema and pneumothorax Respiratory 0.989 0.931 – 1.05 0.733 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 1.02 0.996 – 1.05 0.106 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.06 1.02 – 1.11 0.00726 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.04 0.995 – 1.08 0.0883 2599 26031 all phecode
509.1 Respiratory failure Respiratory 1.05 1 – 1.1 0.0382 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 1.05 1 – 1.1 0.0468 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 0.957 0.807 – 1.14 0.616 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.94 0.846 – 1.04 0.244 386 3863 all phecode
510 Other diseases of lung Respiratory 0.99 0.92 – 1.07 0.795 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 1.01 0.984 – 1.03 0.614 9031 90349 all phecode
512.1 Wheezing Respiratory 1.01 0.881 – 1.15 0.904 220 2196 all phecode
512.2 Painful respiration Respiratory 0.903 0.78 – 1.04 0.167 207 2075 all phecode
512.7 Shortness of breath Respiratory 1.02 0.993 – 1.05 0.143 5842 58498 all phecode
512.8 Cough Respiratory 0.987 0.95 – 1.03 0.506 2866 28642 all phecode
512.9 Other dyspnea Respiratory 0.967 0.902 – 1.04 0.334 914 9124 all phecode
513 Respiratory abnormalities Respiratory 0.97 0.894 – 1.05 0.471 611 6112 all phecode
513.3 Hypoventilation Respiratory 0.772 0.614 – 0.971 0.0272 83 830 all phecode
513.4 Hyperventilation Respiratory 1.05 0.932 – 1.19 0.414 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 0.973 0.822 – 1.15 0.748 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 1.03 0.984 – 1.07 0.23 2465 24673 all phecode
516 Abnormal sputum Respiratory 1.01 0.962 – 1.05 0.815 2132 21335 all phecode
516.1 Hemoptysis Respiratory 1.01 0.962 – 1.05 0.776 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.996 0.975 – 1.02 0.678 9366 93681 all phecode
519.2 Respiratory complications Respiratory 1.07 0.955 – 1.2 0.244 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.997 0.975 – 1.02 0.783 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.997 0.887 – 1.12 0.962 303 3049 all phecode
520 Disorders of tooth development Digestive 1 0.957 – 1.05 0.943 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.12 0.849 – 1.47 0.425 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 1.01 0.967 – 1.05 0.67 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 0.993 0.957 – 1.03 0.713 3016 30245 all phecode
521.1 Dental caries Digestive 0.99 0.954 – 1.03 0.604 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 0.978 0.931 – 1.03 0.362 1774 17750 all phecode
522.5 Periapical abscess Digestive 0.994 0.937 – 1.06 0.846 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 0.998 0.95 – 1.05 0.95 1681 16812 all phecode
523.1 Gingivitis Digestive 1.03 0.851 – 1.24 0.776 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.02 0.959 – 1.08 0.549 1165 11650 all phecode
523.31 Acute periodontitis Digestive 0.969 0.895 – 1.05 0.445 666 6667 all phecode
523.32 Chronic periodontitis Digestive 1.08 0.987 – 1.17 0.0942 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.95 0.848 – 1.07 0.382 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.965 0.857 – 1.09 0.555 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.02 0.982 – 1.06 0.277 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.81 0.629 – 1.04 0.102 72 720 all phecode
526 Diseases of the jaws Digestive 1.02 0.949 – 1.09 0.647 928 9279 all phecode
526.1 Cysts of the jaws Digestive 1.01 0.9 – 1.13 0.869 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.17 0.91 – 1.5 0.224 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.06 0.931 – 1.2 0.381 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.05 0.923 – 1.2 0.444 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 1.04 0.859 – 1.26 0.687 110 1098 all phecode
526.9 Jaw disease NOS Digestive 0.922 0.805 – 1.06 0.243 233 2329 all phecode
527 Diseases of the salivary glands Digestive 1.03 0.954 – 1.11 0.446 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.15 0.923 – 1.44 0.212 84 838 all phecode
527.2 Sialoadenitis Digestive 1.01 0.911 – 1.13 0.817 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 1.09 0.849 – 1.41 0.49 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.01 0.836 – 1.21 0.933 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.987 0.955 – 1.02 0.451 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 1.07 0.974 – 1.18 0.16 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.1 0.99 – 1.22 0.0756 389 3884 all phecode
528.12 Oral aphthae Digestive 0.939 0.752 – 1.17 0.581 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.894 0.766 – 1.04 0.16 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 0.883 0.736 – 1.06 0.184 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 0.954 0.774 – 1.17 0.656 94 940 all phecode
528.5 Diseases of lips Digestive 1.01 0.936 – 1.09 0.769 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 0.923 0.819 – 1.04 0.191 308 3079 all phecode
528.7 Sialolithiasis Digestive 1.01 0.901 – 1.13 0.861 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 1.04 0.977 – 1.1 0.238 1232 12312 all phecode
529.1 Glossitis Digestive 1 0.892 – 1.13 0.943 299 2986 all phecode
530 Diseases of esophagus Digestive 1 0.99 – 1.01 0.884 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1 0.988 – 1.01 0.963 31253 272429 all phecode
530.11 GERD Digestive 0.995 0.982 – 1.01 0.491 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 1.01 0.98 – 1.04 0.573 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 0.989 0.97 – 1.01 0.293 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.99 0.942 – 1.04 0.686 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.01 0.96 – 1.05 0.802 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 1 0.924 – 1.09 0.962 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.917 0.773 – 1.09 0.314 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.974 0.872 – 1.09 0.641 341 3416 all phecode
530.9 Heartburn Digestive 0.999 0.955 – 1.05 0.969 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.01 0.981 – 1.03 0.687 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.09 1 – 1.18 0.0395 637 6374 all phecode
531.2 Gastric ulcer Digestive 0.998 0.966 – 1.03 0.912 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 0.998 0.961 – 1.04 0.916 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 0.971 0.879 – 1.07 0.562 427 4268 all phecode
532 Dysphagia Digestive 0.989 0.964 – 1.01 0.392 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 1 0.99 – 1.01 0.756 28078 261548 all phecode
535.1 Acute gastritis Digestive 0.961 0.905 – 1.02 0.189 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 1.01 0.907 – 1.12 0.882 370 3687 all phecode
535.6 Duodenitis Digestive 0.998 0.975 – 1.02 0.868 7592 75928 all phecode
535.8 Other specified gastritis Digestive 0.994 0.971 – 1.02 0.597 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.03 0.853 – 1.24 0.774 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.966 0.849 – 1.1 0.605 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 1.01 0.975 – 1.05 0.585 3391 33907 all phecode
540 Appendiceal conditions Digestive 0.997 0.961 – 1.03 0.871 3088 30890 all phecode
540.1 Appendicitis Digestive 0.981 0.944 – 1.02 0.31 2895 28963 all phecode
540.11 Acute appendicitis Digestive 0.973 0.934 – 1.01 0.179 2601 26019 all phecode
550 Abdominal hernia Digestive 0.994 0.985 – 1 0.279 45429 282640 all phecode
550.1 Inguinal hernia Digestive 0.995 0.979 – 1.01 0.568 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 0.993 0.98 – 1.01 0.253 26494 238953 all phecode
550.3 Femoral hernia Digestive 0.974 0.899 – 1.06 0.528 651 6504 all phecode
550.4 Umbilical hernia Digestive 0.983 0.95 – 1.02 0.315 3705 37072 all phecode
550.5 Ventral hernia Digestive 0.996 0.962 – 1.03 0.834 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 0.989 0.959 – 1.02 0.498 4444 44442 all phecode
555.1 Regional enteritis Digestive 0.968 0.921 – 1.02 0.198 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 0.999 0.963 – 1.04 0.94 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.02 0.934 – 1.12 0.646 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 1.05 0.985 – 1.12 0.138 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 1.04 0.962 – 1.12 0.327 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.989 0.878 – 1.11 0.853 299 2987 all phecode
557.1 Celiac disease Digestive 1.02 0.968 – 1.07 0.536 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 1 0.984 – 1.02 0.953 15492 155105 all phecode
559 Ileostomy status Digestive 0.995 0.946 – 1.05 0.844 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.01 0.975 – 1.04 0.634 3936 39337 all phecode
560.1 Paralytic ileus Digestive 1.06 0.967 – 1.16 0.22 523 5231 all phecode
560.2 Impaction of intestine Digestive 0.998 0.88 – 1.13 0.974 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.979 0.911 – 1.05 0.555 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 1.01 0.971 – 1.04 0.738 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 1.02 1 – 1.04 0.012 15772 157686 all phecode
561.1 Diarrhea Digestive 1.04 0.95 – 1.15 0.37 466 4653 all phecode
561.2 Flatulence Digestive 1.02 0.967 – 1.07 0.517 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 0.989 0.976 – 1 0.0796 26714 211692 all phecode
562.1 Diverticulosis Digestive 0.989 0.976 – 1 0.0806 26672 211642 all phecode
563 Constipation Digestive 0.99 0.971 – 1.01 0.352 10314 103140 all phecode
564 Functional digestive disorders Digestive 1 0.987 – 1.02 0.886 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.02 0.988 – 1.04 0.282 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 0.984 0.935 – 1.04 0.54 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 0.997 0.981 – 1.01 0.732 15186 151648 all phecode
565 Anal and rectal conditions Digestive 0.977 0.961 – 0.994 0.00844 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 0.967 0.944 – 0.99 0.00548 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 0.971 0.908 – 1.04 0.385 929 9293 all phecode
568 Other disorders of peritoneum Digestive 0.998 0.963 – 1.03 0.917 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1 0.963 – 1.04 0.982 3101 30987 all phecode
569 Other disorders of intestine Digestive 1.02 0.99 – 1.05 0.181 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.01 0.856 – 1.18 0.94 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 0.928 0.846 – 1.02 0.117 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.01 0.977 – 1.05 0.448 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.02 0.973 – 1.07 0.377 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.03 0.847 – 1.25 0.775 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 1.05 0.929 – 1.19 0.426 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.993 0.929 – 1.06 0.829 976 9804 all phecode
571.81 Portal hypertension Digestive 0.979 0.895 – 1.07 0.635 528 5285 all phecode
572 Ascites (non malignant) Digestive 1 0.949 – 1.05 0.991 1544 15454 all phecode
573 Other disorders of liver Digestive 0.977 0.926 – 1.03 0.388 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 0.887 0.714 – 1.1 0.277 96 960 all phecode
573.3 Hepatomegaly Digestive 1.02 0.91 – 1.15 0.709 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 1.01 0.944 – 1.08 0.755 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 1 0.967 – 1.04 0.951 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.15 1 – 1.32 0.0485 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 1 0.987 – 1.02 0.73 15607 156123 all phecode
574.1 Cholelithiasis Digestive 0.998 0.981 – 1.02 0.832 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.99 0.939 – 1.04 0.71 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.01 0.985 – 1.04 0.363 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 1.01 0.966 – 1.05 0.793 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.995 0.957 – 1.04 0.807 2748 27523 all phecode
575 Other biliary tract disease Digestive 0.995 0.962 – 1.03 0.743 3867 38724 all phecode
575.1 Cholangitis Digestive 0.944 0.86 – 1.04 0.219 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 1.02 0.948 – 1.1 0.595 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 1.01 0.914 – 1.11 0.899 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 1.01 0.955 – 1.06 0.757 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 0.986 0.926 – 1.05 0.661 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.977 0.877 – 1.09 0.679 348 3488 all phecode
577 Diseases of pancreas Digestive 0.999 0.96 – 1.04 0.949 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 1 0.96 – 1.05 0.835 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 0.99 0.905 – 1.08 0.821 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.04 0.933 – 1.15 0.496 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 1 0.989 – 1.02 0.638 20626 206278 all phecode
578.1 Hematemesis Digestive 1.04 0.989 – 1.09 0.132 1958 19564 all phecode
578.2 Blood in stool Digestive 0.992 0.953 – 1.03 0.696 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.01 0.993 – 1.03 0.214 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.986 0.959 – 1.01 0.339 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.03 0.982 – 1.09 0.201 1548 15498 all phecode
579.2 Splenomegaly Digestive 0.974 0.882 – 1.08 0.598 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.975 0.927 – 1.03 0.333 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.01 0.959 – 1.07 0.691 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 0.99 0.929 – 1.06 0.761 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.944 0.749 – 1.19 0.625 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.911 0.76 – 1.09 0.311 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1 0.937 – 1.08 0.898 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.1 1 – 1.21 0.0432 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.954 0.836 – 1.09 0.479 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.953 0.836 – 1.09 0.465 253 2529 all phecode
585 Renal failure Genitourinary 0.998 0.974 – 1.02 0.892 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 1.02 0.993 – 1.06 0.127 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 0.964 0.913 – 1.02 0.179 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.977 0.938 – 1.02 0.248 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 0.986 0.898 – 1.08 0.76 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.03 0.992 – 1.07 0.126 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.86 0.744 – 0.993 0.0395 208 2089 all phecode
586.11 Small kidney Genitourinary 0.877 0.751 – 1.02 0.0989 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.03 0.975 – 1.1 0.266 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.964 0.773 – 1.2 0.744 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.996 0.931 – 1.07 0.917 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 1.06 0.955 – 1.18 0.262 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.11 0.908 – 1.35 0.318 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.07 0.888 – 1.28 0.493 116 1158 all phecode
590 Pyelonephritis Genitourinary 1.03 0.976 – 1.09 0.263 1328 13285 all phecode
591 Urinary tract infection Genitourinary 1.01 0.991 – 1.03 0.297 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 0.979 0.942 – 1.02 0.264 2966 29661 all phecode
592.1 Cystitis Genitourinary 0.978 0.941 – 1.02 0.26 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 0.881 0.739 – 1.05 0.158 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 1.01 0.942 – 1.08 0.786 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 1.05 0.922 – 1.19 0.468 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.05 0.899 – 1.23 0.522 165 1662 all phecode
593 Hematuria Genitourinary 0.994 0.978 – 1.01 0.455 16068 160204 all phecode
594 Urinary calculus Genitourinary 0.974 0.949 – 1 0.0464 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 0.968 0.934 – 1 0.087 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 0.98 0.911 – 1.05 0.589 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 0.985 0.945 – 1.03 0.491 2401 24024 all phecode
594.8 Renal colic Genitourinary 0.998 0.954 – 1.04 0.932 2050 20500 all phecode
595 Hydronephrosis Genitourinary 1.02 0.972 – 1.07 0.431 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 0.979 0.959 – 1 0.0486 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 0.978 0.934 – 1.02 0.349 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 0.964 0.917 – 1.01 0.16 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.991 0.959 – 1.02 0.583 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.991 0.956 – 1.03 0.608 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 1.09 0.878 – 1.36 0.428 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 0.991 0.957 – 1.03 0.592 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.04 0.922 – 1.16 0.55 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.991 0.976 – 1.01 0.255 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 0.938 0.801 – 1.1 0.428 166 1670 all phecode
599.2 Retention of urine Genitourinary 0.983 0.958 – 1.01 0.17 6718 67168 all phecode
599.3 Dysuria Genitourinary 0.971 0.915 – 1.03 0.333 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 0.993 0.972 – 1.02 0.546 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1 0.972 – 1.04 0.802 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 1.01 0.825 – 1.24 0.923 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.13 0.864 – 1.47 0.377 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 0.945 0.901 – 0.991 0.0197 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 0.968 0.949 – 0.987 0.00125 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 1.01 0.969 – 1.06 0.569 2081 20818 all phecode
601.1 Prostatitis Genitourinary 0.996 0.946 – 1.05 0.886 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 0.991 0.866 – 1.13 0.895 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 0.945 0.882 – 1.01 0.105 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 0.857 0.656 – 1.12 0.258 59 588 all phecode
601.4 Balanoposthitis Genitourinary 1.03 0.908 – 1.16 0.678 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.15 1.02 – 1.29 0.021 303 3019 all phecode
602 Other disorders of prostate Genitourinary 0.984 0.93 – 1.04 0.569 1341 13408 all phecode
603 Other disorders of testis Genitourinary 0.987 0.944 – 1.03 0.559 2150 21512 all phecode
603.1 Hydrocele Genitourinary 1.02 0.96 – 1.07 0.586 1339 13402 all phecode
604 Disorders of penis Genitourinary 1.02 0.985 – 1.06 0.267 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.03 0.989 – 1.07 0.164 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.03 0.91 – 1.16 0.662 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 0.986 0.949 – 1.03 0.488 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.01 0.873 – 1.16 0.924 214 2138 all phecode
609.1 Infertility, male Genitourinary 1.18 0.916 – 1.51 0.203 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.942 0.802 – 1.11 0.467 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 1.06 1.01 – 1.1 0.00758 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 1.02 0.956 – 1.09 0.524 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.06 0.944 – 1.2 0.316 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 1.13 1.01 – 1.27 0.0304 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 1.08 1.02 – 1.14 0.00448 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.03 0.954 – 1.11 0.444 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.12 1.06 – 1.18 1.82e-05 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 1.31 1.01 – 1.7 0.0446 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 1.11 1.06 – 1.17 5.19e-05 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.17 1.09 – 1.25 6.2e-06 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.18 1.11 – 1.27 1.6e-06 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 1.05 0.833 – 1.32 0.691 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 1.1 1.05 – 1.16 0.000114 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.06 0.987 – 1.15 0.106 720 7210 all phecode
613.5 Mastodynia Genitourinary 1.16 0.916 – 1.46 0.221 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 1.11 1.03 – 1.2 0.00622 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 1.18 1.05 – 1.31 0.00429 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 1.08 0.938 – 1.24 0.288 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.01 0.985 – 1.04 0.404 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.03 0.985 – 1.07 0.21 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.01 0.942 – 1.09 0.726 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.23 0.941 – 1.61 0.13 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.05 0.95 – 1.16 0.331 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.942 0.844 – 1.05 0.289 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.07 0.949 – 1.21 0.266 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.989 0.949 – 1.03 0.576 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.989 0.934 – 1.05 0.691 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.03 0.933 – 1.14 0.547 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.969 0.898 – 1.04 0.411 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.03 0.911 – 1.17 0.631 274 2737 all phecode
615 Endometriosis Genitourinary 1.01 0.974 – 1.04 0.711 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 0.944 0.839 – 1.06 0.331 304 3037 all phecode
618 Genital prolapse Genitourinary 0.98 0.962 – 0.999 0.0413 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 0.979 0.956 – 1 0.0852 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.963 0.937 – 0.991 0.00957 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.927 0.846 – 1.02 0.103 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.07 0.991 – 1.16 0.0846 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 1.02 0.998 – 1.04 0.0731 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.03 0.958 – 1.11 0.398 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 0.998 0.963 – 1.03 0.906 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.02 0.98 – 1.06 0.349 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.05 0.997 – 1.1 0.0658 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.05 0.996 – 1.11 0.0703 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 1.01 0.801 – 1.26 0.959 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 1.03 0.971 – 1.1 0.309 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 1.03 1.01 – 1.05 0.0108 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 1.02 0.997 – 1.04 0.0936 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 1.04 1 – 1.08 0.0267 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.01 0.953 – 1.07 0.755 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 0.929 0.863 – 1 0.0487 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.882 0.772 – 1.01 0.0661 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.949 0.86 – 1.05 0.293 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 0.978 0.952 – 1.01 0.113 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.01 0.968 – 1.04 0.769 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 1.02 0.961 – 1.08 0.529 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.01 0.993 – 1.03 0.272 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.01 0.988 – 1.02 0.513 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 1.05 0.866 – 1.28 0.61 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.01 0.984 – 1.03 0.626 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 1.01 0.968 – 1.06 0.566 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 1.01 0.98 – 1.05 0.441 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 0.982 0.936 – 1.03 0.469 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 1 0.851 – 1.18 0.967 159 1587 all phecode
626.8 Infertility, female Genitourinary 1.01 0.957 – 1.07 0.709 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.02 1 – 1.04 0.0264 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 1.02 0.999 – 1.04 0.0559 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 0.976 0.837 – 1.14 0.757 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.03 0.971 – 1.1 0.302 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.996 0.884 – 1.12 0.948 310 3097 all phecode
628 Ovarian cyst Genitourinary 0.988 0.959 – 1.02 0.425 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.02 0.994 – 1.05 0.124 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.997 0.938 – 1.06 0.925 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.09 0.972 – 1.21 0.144 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.07 1.02 – 1.12 0.00648 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.06 0.986 – 1.13 0.118 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.07 1.01 – 1.13 0.0273 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.04 0.993 – 1.08 0.0967 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 1.03 0.949 – 1.12 0.464 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.07 1.01 – 1.14 0.0278 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 1.3 1.02 – 1.65 0.0349 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.05 0.986 – 1.12 0.127 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.01 0.9 – 1.14 0.844 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.01 0.88 – 1.15 0.908 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.07 0.911 – 1.25 0.424 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.03 0.969 – 1.09 0.375 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.03 0.981 – 1.07 0.264 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.37 1.07 – 1.74 0.0126 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.974 0.861 – 1.1 0.682 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.2 0.985 – 1.46 0.0699 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.04 0.899 – 1.2 0.61 193 1922 all phecode
650 Normal delivery Pregnancy Complications 1.02 0.972 – 1.07 0.44 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 1.02 0.912 – 1.14 0.729 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1.01 0.963 – 1.06 0.625 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.01 0.958 – 1.07 0.681 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.32 1.05 – 1.66 0.0189 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.01 0.976 – 1.04 0.611 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.07 0.882 – 1.3 0.486 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 1.05 1 – 1.09 0.0364 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 1 0.916 – 1.09 0.98 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 1.04 1.01 – 1.07 0.0134 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.04 0.998 – 1.08 0.0618 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1 0.849 – 1.18 0.997 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.998 0.88 – 1.13 0.978 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.1 0.855 – 1.41 0.462 63 624 all phecode
679 Complications of in utero procedures Dermatologic 1.1 0.852 – 1.42 0.459 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 0.981 0.958 – 1.01 0.125 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.03 0.947 – 1.13 0.466 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.965 0.881 – 1.06 0.437 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.975 0.948 – 1 0.0706 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.975 0.949 – 1 0.0776 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.972 0.946 – 1 0.0492 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.1 1.01 – 1.19 0.0322 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.03 0.974 – 1.09 0.299 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 0.976 0.935 – 1.02 0.267 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 0.996 0.916 – 1.08 0.927 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 0.921 0.827 – 1.03 0.133 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1.08 0.993 – 1.18 0.0712 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.02 0.978 – 1.07 0.325 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.11 0.984 – 1.25 0.0893 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 1 0.828 – 1.22 0.964 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.04 1 – 1.08 0.0481 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.03 1 – 1.06 0.0539 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.899 0.708 – 1.14 0.382 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.864 0.654 – 1.14 0.3 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 1.23 1.02 – 1.48 0.0314 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 1.04 0.974 – 1.11 0.238 986 9854 all phecode
694.1 Vitiligo Dermatologic 1.07 0.837 – 1.37 0.587 60 599 all phecode
694.2 Other dyschromia Dermatologic 1.03 0.955 – 1.11 0.472 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 0.989 0.822 – 1.19 0.911 117 1170 all phecode
695 Erythematous conditions Dermatologic 1.01 0.966 – 1.05 0.716 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 1.02 0.841 – 1.24 0.828 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 0.97 0.817 – 1.15 0.733 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 1.01 0.783 – 1.3 0.951 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.957 0.761 – 1.2 0.707 73 727 all phecode
695.3 Rosacea Dermatologic 1.02 0.905 – 1.14 0.787 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1 0.904 – 1.11 0.993 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.07 0.892 – 1.28 0.479 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 0.969 0.868 – 1.08 0.585 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 0.988 0.918 – 1.06 0.753 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 1 0.876 – 1.14 0.992 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 1.12 0.885 – 1.41 0.352 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.04 0.943 – 1.14 0.465 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 1.01 0.967 – 1.05 0.657 2252 22509 all phecode
696.4 Psoriasis Dermatologic 1.01 0.966 – 1.05 0.67 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.03 0.983 – 1.09 0.198 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 0.94 0.869 – 1.02 0.119 706 7052 all phecode
697 Sarcoidosis Dermatologic 1.03 0.941 – 1.12 0.537 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 0.997 0.927 – 1.07 0.935 782 7814 all phecode
700 Corns and callosities Dermatologic 0.976 0.867 – 1.1 0.691 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.03 1 – 1.07 0.0254 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 1.03 0.815 – 1.29 0.822 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.06 1.02 – 1.11 0.00567 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.06 0.828 – 1.36 0.639 61 610 all phecode
701.4 Keloid scar Dermatologic 1.13 0.982 – 1.3 0.0874 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.03 0.94 – 1.14 0.482 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 0.922 0.751 – 1.13 0.439 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.998 0.97 – 1.03 0.864 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 1 0.962 – 1.04 0.912 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 0.987 0.951 – 1.02 0.492 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 1.03 0.926 – 1.15 0.568 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 0.969 0.907 – 1.03 0.344 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 0.994 0.966 – 1.02 0.673 5267 52727 all phecode
704.1 Alopecia Dermatologic 1.05 0.883 – 1.26 0.56 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.815 0.647 – 1.03 0.0821 76 759 all phecode
705 Disorders of sweat glands Dermatologic 1.06 0.923 – 1.21 0.42 228 2287 all phecode
705.3 Hidradenitis Dermatologic 1.09 0.937 – 1.26 0.275 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 1.01 0.931 – 1.11 0.74 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 1.01 0.986 – 1.03 0.474 8317 83195 all phecode
706.1 Acne Dermatologic 1.16 0.908 – 1.48 0.237 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 1 0.981 – 1.03 0.791 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 1.01 0.963 – 1.06 0.716 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 1.02 0.952 – 1.09 0.591 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 1.03 0.997 – 1.07 0.0761 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 0.937 0.856 – 1.03 0.155 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 0.985 0.843 – 1.15 0.846 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.25 0.974 – 1.59 0.0794 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.04 0.996 – 1.08 0.0825 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.06 0.977 – 1.16 0.154 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 1.05 0.962 – 1.15 0.276 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.12 0.963 – 1.3 0.145 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.979 0.883 – 1.09 0.691 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 0.997 0.902 – 1.1 0.948 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 0.958 0.856 – 1.07 0.45 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 0.946 0.755 – 1.18 0.628 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.06 0.897 – 1.26 0.477 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.1 0.852 – 1.42 0.469 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.989 0.96 – 1.02 0.464 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.985 0.955 – 1.02 0.351 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.953 0.906 – 1 0.0637 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.05 0.867 – 1.27 0.614 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.939 0.864 – 1.02 0.14 618 6177 all phecode
716 Other arthropathies Musculoskeletal 0.982 0.972 – 0.993 0.00128 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.99 0.956 – 1.03 0.563 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.976 0.96 – 0.992 0.00353 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 0.982 0.971 – 0.993 0.00151 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.04 0.982 – 1.11 0.169 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 1 0.969 – 1.04 0.894 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1 0.978 – 1.02 0.941 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1 0.972 – 1.03 0.966 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.05 0.906 – 1.22 0.51 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 0.918 0.823 – 1.02 0.127 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 0.999 0.977 – 1.02 0.906 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.03 0.938 – 1.13 0.551 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.991 0.954 – 1.03 0.661 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 0.913 0.707 – 1.18 0.483 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.988 0.958 – 1.02 0.456 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 1.07 0.975 – 1.16 0.16 517 5173 all phecode
723.1 Torticollis Musculoskeletal 1.2 0.99 – 1.46 0.0634 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.01 0.962 – 1.05 0.77 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 0.975 0.878 – 1.08 0.631 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 0.98 0.883 – 1.09 0.697 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 0.856 0.662 – 1.11 0.239 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.02 0.967 – 1.07 0.511 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.01 0.99 – 1.02 0.422 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 1 0.979 – 1.02 0.985 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 0.997 0.891 – 1.11 0.953 334 3336 all phecode
726.3 Bursitis Musculoskeletal 0.994 0.926 – 1.07 0.856 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.01 0.982 – 1.03 0.655 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.02 0.984 – 1.06 0.253 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 1.18 0.966 – 1.45 0.104 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.99 0.954 – 1.03 0.587 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 1.03 0.943 – 1.12 0.54 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.965 0.865 – 1.08 0.526 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.04 0.877 – 1.24 0.638 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.03 0.991 – 1.06 0.147 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.05 0.949 – 1.16 0.355 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 1.02 0.99 – 1.06 0.169 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.02 0.988 – 1.06 0.205 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 0.999 0.973 – 1.03 0.928 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.02 0.96 – 1.09 0.471 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 1.01 0.825 – 1.25 0.889 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.04 0.919 – 1.17 0.544 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.05 0.923 – 1.19 0.48 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 1.02 0.932 – 1.13 0.617 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.1 0.953 – 1.26 0.2 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.976 0.744 – 1.28 0.863 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.993 0.946 – 1.04 0.786 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 1.07 0.947 – 1.2 0.293 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.99 0.906 – 1.08 0.82 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 0.962 0.801 – 1.15 0.677 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.962 0.907 – 1.02 0.199 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 0.885 0.731 – 1.07 0.212 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 0.988 0.968 – 1.01 0.28 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 0.988 0.85 – 1.15 0.875 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 0.981 0.953 – 1.01 0.205 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.944 0.901 – 0.99 0.0167 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 1.05 0.995 – 1.1 0.0785 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.98 0.955 – 1 0.113 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.996 0.946 – 1.05 0.888 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.03 0.9 – 1.17 0.685 248 2476 all phecode
737 Curvature of spine Musculoskeletal 1 0.941 – 1.06 0.997 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.987 0.926 – 1.05 0.674 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.997 0.951 – 1.05 0.913 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.981 0.93 – 1.03 0.471 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 1.03 0.941 – 1.13 0.495 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 0.989 0.976 – 1 0.073 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.989 0.973 – 1 0.157 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.992 0.971 – 1.01 0.469 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.08 0.97 – 1.21 0.157 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.01 0.932 – 1.1 0.741 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.995 0.977 – 1.01 0.625 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.985 0.952 – 1.02 0.395 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 0.974 0.796 – 1.19 0.801 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 0.99 0.912 – 1.07 0.809 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 1.12 0.955 – 1.32 0.16 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 0.961 0.909 – 1.02 0.156 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 0.881 0.726 – 1.07 0.199 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 1.21 0.919 – 1.6 0.173 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.994 0.956 – 1.03 0.744 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 1.03 0.923 – 1.16 0.57 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.991 0.801 – 1.22 0.93 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 0.875 0.797 – 0.96 0.00485 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 1.01 0.964 – 1.06 0.687 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.02 0.998 – 1.05 0.0781 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 1.02 0.996 – 1.05 0.0919 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 1.03 1.01 – 1.06 0.0156 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 0.985 0.9 – 1.08 0.741 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 0.949 0.866 – 1.04 0.258 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.08 1 – 1.16 0.0407 815 8144 all phecode
745 Pain in joint Musculoskeletal 1 0.977 – 1.02 0.987 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.948 0.912 – 0.986 0.00801 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.951 0.913 – 0.99 0.015 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.93 0.852 – 1.01 0.102 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.908 0.792 – 1.04 0.167 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.952 0.907 – 0.999 0.0472 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.887 0.751 – 1.05 0.16 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.09 0.814 – 1.45 0.569 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.991 0.883 – 1.11 0.876 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.96 0.887 – 1.04 0.301 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.08 0.963 – 1.21 0.191 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.09 0.941 – 1.27 0.245 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.877 0.787 – 0.978 0.0184 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.845 0.737 – 0.969 0.0161 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.893 0.737 – 1.08 0.243 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.999 0.948 – 1.05 0.974 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.02 0.946 – 1.1 0.597 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.03 0.942 – 1.14 0.482 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.988 0.859 – 1.14 0.867 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.996 0.928 – 1.07 0.918 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.976 0.883 – 1.08 0.634 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.02 0.915 – 1.15 0.679 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.11 0.989 – 1.24 0.0764 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 1.08 0.954 – 1.23 0.216 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 1.1 0.951 – 1.26 0.203 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.06 0.842 – 1.33 0.621 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.937 0.784 – 1.12 0.474 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.99 0.786 – 1.25 0.933 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.03 0.848 – 1.26 0.735 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.964 0.871 – 1.07 0.474 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.976 0.844 – 1.13 0.745 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.916 0.779 – 1.08 0.286 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.889 0.729 – 1.09 0.248 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.93 0.853 – 1.01 0.1 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.811 0.647 – 1.02 0.071 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.92 0.832 – 1.02 0.104 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.993 0.842 – 1.17 0.934 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.09 0.85 – 1.41 0.486 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.993 0.87 – 1.13 0.921 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.893 0.727 – 1.1 0.28 96 959 all phecode
760 Back pain Symptoms 1.01 0.995 – 1.03 0.157 11126 111353 all phecode
761 Cervicalgia Symptoms 0.99 0.942 – 1.04 0.672 1791 17901 all phecode
764 Sciatica Symptoms 1.01 0.967 – 1.05 0.687 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.01 0.952 – 1.08 0.705 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 1.03 0.954 – 1.12 0.415 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.961 0.896 – 1.03 0.268 870 8687 all phecode
771.1 Swelling of limb Symptoms 0.999 0.97 – 1.03 0.967 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 1.03 0.949 – 1.11 0.506 659 6581 all phecode
773 Pain in limb Symptoms 0.995 0.969 – 1.02 0.694 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 1.16 0.992 – 1.36 0.0621 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.983 0.937 – 1.03 0.469 1870 18715 all phecode
782.3 Edema Symptoms 1.01 0.961 – 1.06 0.668 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 0.96 0.821 – 1.12 0.604 175 1748 all phecode
783 Fever of unknown origin Symptoms 1.02 0.983 – 1.05 0.343 3911 39105 all phecode
785 Abdominal pain Symptoms 1.01 0.998 – 1.02 0.0946 40080 301686 all phecode
788 Syncope and collapse Symptoms 0.998 0.977 – 1.02 0.871 9069 90813 all phecode
789 Nausea and vomiting Symptoms 1 0.984 – 1.02 0.783 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.05 0.889 – 1.24 0.554 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 1.01 0.811 – 1.26 0.928 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 0.972 0.947 – 0.997 0.029 6357 63635 all phecode
791 Gangrene Symptoms 0.989 0.906 – 1.08 0.805 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.984 0.798 – 1.21 0.881 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.12 0.944 – 1.32 0.198 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.04 0.954 – 1.13 0.373 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.909 0.757 – 1.09 0.305 120 1198 all phecode
797 Shock Symptoms 1.05 0.891 – 1.23 0.58 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 1.13 0.928 – 1.38 0.221 102 1020 all phecode
798 Malaise and fatigue Symptoms 1.04 1 – 1.07 0.0513 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 1.08 0.995 – 1.18 0.0659 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 1.01 0.989 – 1.04 0.27 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.996 0.949 – 1.05 0.875 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.883 0.757 – 1.03 0.117 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.01 0.966 – 1.05 0.681 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 1.07 0.994 – 1.15 0.0704 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.02 0.974 – 1.06 0.451 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.02 0.974 – 1.07 0.383 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 1.03 0.955 – 1.11 0.44 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 1.02 0.998 – 1.04 0.0796 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.03 0.977 – 1.08 0.299 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1 0.974 – 1.03 0.858 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.05 1 – 1.11 0.0494 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.984 0.949 – 1.02 0.37 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.04 0.983 – 1.1 0.179 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 1.04 0.966 – 1.12 0.296 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.01 0.957 – 1.07 0.647 1300 12998 all phecode
817 Concussion Injuries & Poisonings 0.931 0.815 – 1.06 0.289 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.966 0.882 – 1.06 0.454 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.03 0.989 – 1.07 0.171 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 1 0.953 – 1.05 0.948 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 1.01 0.964 – 1.05 0.732 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 0.999 0.982 – 1.02 0.873 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.05 0.963 – 1.15 0.256 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 0.976 0.886 – 1.08 0.627 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1 0.974 – 1.03 0.871 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.971 0.827 – 1.14 0.72 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 0.953 0.87 – 1.04 0.294 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.993 0.946 – 1.04 0.768 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.964 0.909 – 1.02 0.214 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.969 0.934 – 1.01 0.0967 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.01 0.977 – 1.05 0.491 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 0.939 0.728 – 1.21 0.629 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.03 0.992 – 1.06 0.136 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.08 0.952 – 1.22 0.239 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.996 0.859 – 1.15 0.953 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.03 0.996 – 1.07 0.0813 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.07 0.935 – 1.23 0.314 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 0.995 0.774 – 1.28 0.97 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 0.991 0.96 – 1.02 0.603 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.06 0.808 – 1.4 0.661 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.08 0.877 – 1.34 0.459 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.964 0.829 – 1.12 0.639 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 1 0.909 – 1.1 0.997 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 0.967 0.844 – 1.11 0.629 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 0.983 0.84 – 1.15 0.832 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 0.981 0.835 – 1.15 0.818 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 0.991 0.937 – 1.05 0.764 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.02 0.988 – 1.05 0.224 4260 42663 all phecode
916 Contusion Injuries & Poisonings 0.978 0.927 – 1.03 0.429 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 1.04 0.892 – 1.21 0.636 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.02 0.918 – 1.13 0.728 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.972 0.853 – 1.11 0.675 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.962 0.919 – 1.01 0.0917 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1 0.875 – 1.14 0.995 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.03 0.846 – 1.25 0.774 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.01 0.925 – 1.1 0.827 550 5509 all phecode
947 Urticaria Injuries & Poisonings 0.956 0.86 – 1.06 0.399 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 0.887 0.8 – 0.985 0.0246 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.04 0.937 – 1.14 0.495 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.04 0.915 – 1.17 0.585 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1 0.917 – 1.1 0.923 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.13 0.873 – 1.47 0.345 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.21 0.961 – 1.52 0.105 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.01 0.996 – 1.03 0.137 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.01 0.993 – 1.03 0.273 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 0.915 0.827 – 1.01 0.0868 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.06 0.989 – 1.14 0.098 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.05 0.946 – 1.17 0.356 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.941 – 1.17 0.399 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.05 0.917 – 1.21 0.472 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.942 0.834 – 1.06 0.334 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.948 0.838 – 1.07 0.392 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.01 0.98 – 1.03 0.652 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.02 0.959 – 1.08 0.552 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.938 0.855 – 1.03 0.178 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.16 1.05 – 1.28 0.0048 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.988 0.903 – 1.08 0.783 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.09 1 – 1.19 0.038 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.02 0.971 – 1.07 0.479 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.06 0.912 – 1.22 0.467 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.05 0.932 – 1.18 0.415 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.1 0.887 – 1.36 0.385 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 0.891 0.728 – 1.09 0.262 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.02 0.83 – 1.26 0.825 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.12 0.878 – 1.44 0.353 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.05 0.808 – 1.36 0.714 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.969 0.848 – 1.11 0.644 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.02 0.941 – 1.1 0.67 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.983 0.853 – 1.13 0.818 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 0.984 0.759 – 1.27 0.902 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 0.992 0.814 – 1.21 0.934 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.956 0.789 – 1.16 0.643 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.994 0.798 – 1.24 0.958 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.07 1.04 – 1.11 0.000123 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.05 1.01 – 1.08 0.0194 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 1.05 1.01 – 1.08 0.0194 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 0.992 0.97 – 1.02 0.512 8379 85301 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 0.957 0.919 – 0.997 0.0337 2590 26211 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.936 0.859 – 1.02 0.126 601 6297 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.06 0.988 – 1.14 0.103 811 8331 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.16 0.889 – 1.52 0.272 54 542 exclusion phecode
010 Tuberculosis Infectious Diseases 1.02 0.867 – 1.2 0.793 158 1619 exclusion phecode
038 Septicemia Infectious Diseases 0.999 0.966 – 1.03 0.953 3636 40570 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1 0.933 – 1.08 0.932 806 8283 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 0.922 0.838 – 1.01 0.0945 469 4877 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1 0.983 – 1.02 0.824 11325 116648 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 0.994 0.956 – 1.03 0.74 2860 30495 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 0.991 0.941 – 1.04 0.741 1576 16002 exclusion phecode
041.4 E. coli Infectious Diseases 1.01 0.971 – 1.05 0.583 2565 26190 exclusion phecode
053 Herpes zoster Infectious Diseases 1.11 0.997 – 1.23 0.057 388 3985 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.18 0.955 – 1.46 0.126 91 914 exclusion phecode
054 Herpes simplex Infectious Diseases 0.985 0.853 – 1.14 0.841 195 2043 exclusion phecode
070 Viral hepatitis Infectious Diseases 0.909 0.832 – 0.992 0.0331 575 5772 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 0.974 0.746 – 1.27 0.847 64 665 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.92 0.761 – 1.11 0.388 129 1306 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 0.882 0.772 – 1.01 0.0629 252 2515 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.13 0.998 – 1.28 0.0531 263 2639 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.02 0.92 – 1.13 0.738 411 4155 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1 0.84 – 1.19 0.996 147 1465 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.896 0.736 – 1.09 0.275 117 1168 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.977 0.914 – 1.04 0.495 964 9684 exclusion phecode
079 Viral infection Infectious Diseases 1.03 0.99 – 1.07 0.14 2646 26769 exclusion phecode
079.1 Varicella infection Infectious Diseases 1.13 0.877 – 1.45 0.345 62 621 exclusion phecode
080 Postoperative infection Infectious Diseases 0.998 0.966 – 1.03 0.89 4013 43412 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 0.979 0.938 – 1.02 0.346 2238 24034 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.97 0.759 – 1.24 0.811 67 692 exclusion phecode
1000 Burns Injuries & Poisonings 1.04 0.955 – 1.13 0.367 565 5660 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 0.984 0.927 – 1.05 0.606 1164 11686 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 0.989 0.961 – 1.02 0.441 5240 52778 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 0.929 0.824 – 1.05 0.226 292 2920 exclusion phecode
1005 Other symptoms Injuries & Poisonings 1.01 0.959 – 1.07 0.614 1318 13963 exclusion phecode
1006 Crushing injury Injuries & Poisonings 0.994 0.875 – 1.13 0.923 256 2525 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 1.08 0.949 – 1.24 0.236 252 2521 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.04 0.972 – 1.11 0.271 993 9977 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 1.01 0.987 – 1.03 0.431 8273 82852 exclusion phecode
1010 Other tests Injuries & Poisonings 1.01 0.979 – 1.03 0.661 5636 57417 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.976 0.955 – 0.998 0.0348 8521 88559 exclusion phecode
1012 Late effect Injuries & Poisonings 0.935 0.761 – 1.15 0.52 103 1023 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.07 0.951 – 1.2 0.26 300 3081 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.09 0.853 – 1.4 0.482 66 649 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 0.992 0.96 – 1.02 0.62 3947 40919 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.01 0.992 – 1.03 0.315 15111 153823 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.932 0.824 – 1.06 0.269 274 2751 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.913 0.804 – 1.04 0.157 268 2689 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.763 0.597 – 0.976 0.0315 73 736 exclusion phecode
110.12 Althete's foot Infectious Diseases 0.777 0.649 – 0.929 0.00569 139 1386 exclusion phecode
112 Candidiasis Infectious Diseases 0.949 0.906 – 0.995 0.0288 1944 20482 exclusion phecode
117 Mycoses Infectious Diseases 0.956 0.84 – 1.09 0.492 255 2636 exclusion phecode
117.4 Aspergillosis Infectious Diseases 0.962 0.815 – 1.13 0.642 155 1600 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.993 0.785 – 1.26 0.952 78 787 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 0.909 0.723 – 1.14 0.415 69 667 exclusion phecode
134 Helminthiases Infectious Diseases 1.04 0.865 – 1.26 0.665 122 1218 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 0.968 0.79 – 1.19 0.758 101 1019 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.03 0.891 – 1.18 0.71 197 1983 exclusion phecode
145 Cancer of mouth Neoplasms 1.03 0.952 – 1.12 0.429 612 6264 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.06 0.947 – 1.2 0.295 299 3043 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.987 0.807 – 1.21 0.895 100 1016 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.36 1.06 – 1.75 0.017 51 531 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.04 0.958 – 1.13 0.347 618 6235 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 0.994 0.872 – 1.13 0.923 246 2476 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.12 0.983 – 1.27 0.0899 263 2610 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 0.89 0.68 – 1.17 0.398 51 549 exclusion phecode
150 Cancer of esophagus Neoplasms 1.08 1.01 – 1.17 0.0351 731 7507 exclusion phecode
151 Cancer of stomach Neoplasms 1.03 0.946 – 1.12 0.485 546 5582 exclusion phecode
153 Colorectal cancer Neoplasms 1.01 0.98 – 1.04 0.514 4395 44434 exclusion phecode
153.2 Colon cancer Neoplasms 1.03 0.997 – 1.07 0.0754 2968 30114 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.979 0.936 – 1.02 0.358 2082 21023 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.975 0.879 – 1.08 0.626 390 3880 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.888 0.754 – 1.05 0.156 155 1545 exclusion phecode
157 Pancreatic cancer Neoplasms 1.02 0.941 – 1.11 0.62 634 6387 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.962 0.901 – 1.03 0.252 1014 10297 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.03 0.999 – 1.06 0.0546 5260 53904 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.986 0.848 – 1.15 0.852 181 1851 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.04 0.898 – 1.2 0.608 196 1964 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.19 1.03 – 1.38 0.0156 183 1825 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.922 0.701 – 1.21 0.558 53 582 exclusion phecode
165 Cancer within the respiratory system Neoplasms 0.96 0.922 – 0.999 0.0441 2621 27408 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 0.949 0.907 – 0.993 0.0227 2065 21597 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 1.01 0.909 – 1.12 0.883 399 4223 exclusion phecode
170.1 Bone cancer Neoplasms 1.1 0.915 – 1.32 0.313 121 1271 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1.03 0.914 – 1.16 0.637 301 3194 exclusion phecode
172 Skin cancer Neoplasms 0.986 0.968 – 1 0.122 12923 130528 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.06 1.01 – 1.1 0.00842 2570 25813 exclusion phecode
172.11 Melanomas of skin Neoplasms 1.06 1.02 – 1.1 0.00574 2599 26116 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.975 0.955 – 0.995 0.0127 10529 106496 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 1 0.925 – 1.09 0.915 634 6438 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.03 0.888 – 1.19 0.7 173 1759 exclusion phecode
175 Acquired absence of breast Neoplasms 0.972 0.765 – 1.24 0.82 63 24010 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 0.988 0.943 – 1.03 0.598 2050 21747 exclusion phecode
180.1 Cervical cancer Neoplasms 1.02 0.896 – 1.16 0.781 251 2720 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1 0.959 – 1.05 0.848 1960 20784 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 1.01 0.948 – 1.07 0.803 1123 12836 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.06 0.996 – 1.12 0.0665 1256 13772 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.1 1.03 – 1.18 0.00737 868 9667 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.09 1.02 – 1.17 0.0121 842 9387 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1 0.89 – 1.13 0.943 286 3049 exclusion phecode
185 Cancer of prostate Neoplasms 0.914 0.889 – 0.938 4.43e-11 5954 58768 exclusion phecode
187 Cancer of other male genital organs Neoplasms 0.961 0.872 – 1.06 0.427 448 4485 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.824 0.641 – 1.06 0.129 70 699 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 1.01 0.894 – 1.14 0.887 287 2868 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.897 0.736 – 1.09 0.282 109 1098 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.946 0.916 – 0.977 0.000857 4020 40759 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.969 0.909 – 1.03 0.328 1034 10461 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.966 0.905 – 1.03 0.297 996 10080 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.11 0.867 – 1.42 0.407 63 646 exclusion phecode
189.2 Cancer of bladder Neoplasms 0.924 0.885 – 0.964 0.000303 2339 23695 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.925 0.884 – 0.968 0.000793 2076 21095 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.858 0.721 – 1.02 0.0864 140 1419 exclusion phecode
190 Cancer of eye Neoplasms 1.14 0.978 – 1.33 0.0934 169 1707 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.05 0.971 – 1.14 0.212 658 6688 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 1.03 0.943 – 1.13 0.512 542 5503 exclusion phecode
191.11 Cancer of brain Neoplasms 1.04 0.947 – 1.14 0.42 504 5095 exclusion phecode
193 Thyroid cancer Neoplasms 0.9 0.801 – 1.01 0.0744 318 3327 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.02 0.822 – 1.26 0.862 88 921 exclusion phecode
195 Cancer, suspected or other Neoplasms 0.991 0.975 – 1.01 0.273 15439 162081 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 0.991 0.975 – 1.01 0.32 14863 156272 exclusion phecode
197 Chemotherapy Neoplasms 1.01 0.998 – 1.03 0.0902 17657 207907 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.01 0.987 – 1.04 0.342 6667 93092 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.01 0.977 – 1.05 0.484 3078 52189 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1 0.958 – 1.05 0.84 1777 22192 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.05 0.992 – 1.11 0.0932 1354 15054 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.04 0.992 – 1.08 0.107 2186 26106 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.05 0.968 – 1.14 0.243 641 8296 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 0.955 0.907 – 1.01 0.0861 1547 21152 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.911 0.769 – 1.08 0.278 149 1849 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 0.966 0.913 – 1.02 0.237 1321 14033 exclusion phecode
199.4 Neurofibromatosis Neoplasms 0.918 0.747 – 1.13 0.417 89 926 exclusion phecode
200 Myeloproliferative disease Neoplasms 0.987 0.923 – 1.05 0.69 961 9626 exclusion phecode
200.1 Polycythemia vera Neoplasms 0.92 0.826 – 1.03 0.131 376 3804 exclusion phecode
201 Hodgkin's disease Neoplasms 0.986 0.869 – 1.12 0.831 250 2530 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.981 0.939 – 1.03 0.397 2162 22008 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.983 0.936 – 1.03 0.505 1743 17502 exclusion phecode
202.21 Nodular lymphoma Neoplasms 0.988 0.885 – 1.1 0.833 354 3530 exclusion phecode
202.24 Large cell lymphoma Neoplasms 0.931 0.854 – 1.01 0.104 566 5631 exclusion phecode
204 Leukemia Neoplasms 1.03 0.976 – 1.08 0.298 1597 16180 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1.07 0.982 – 1.17 0.119 555 5648 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.03 0.782 – 1.37 0.816 52 549 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.05 0.957 – 1.15 0.3 489 4957 exclusion phecode
204.2 Myeloid leukemia Neoplasms 0.952 0.864 – 1.05 0.322 444 4485 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.925 0.824 – 1.04 0.19 316 3196 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.02 0.863 – 1.21 0.797 139 1394 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.06 0.97 – 1.15 0.206 539 5406 exclusion phecode
208 Benign neoplasm of colon Neoplasms 0.978 0.963 – 0.993 0.0033 19228 186240 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.972 0.909 – 1.04 0.417 936 9450 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.993 0.965 – 1.02 0.647 5006 50361 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.09 0.977 – 1.22 0.122 338 3385 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.924 0.82 – 1.04 0.193 300 3096 exclusion phecode
214 Lipoma Neoplasms 0.997 0.971 – 1.02 0.818 5986 60612 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.998 0.968 – 1.03 0.906 4386 44453 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.01 0.949 – 1.08 0.725 1046 10650 exclusion phecode
216 Benign neoplasm of skin Neoplasms 1.01 0.985 – 1.03 0.474 7309 73983 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.07 0.986 – 1.16 0.103 602 6107 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 1.09 0.996 – 1.18 0.0606 566 5742 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 1.02 0.998 – 1.04 0.0783 9300 94888 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 1.02 1 – 1.05 0.023 9500 96859 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.886 0.791 – 0.992 0.0364 327 3355 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 1.01 0.953 – 1.07 0.792 1338 14483 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.01 0.876 – 1.16 0.898 198 2196 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 1.07 0.91 – 1.26 0.413 159 1600 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.886 0.753 – 1.04 0.144 166 1683 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.924 0.767 – 1.11 0.411 124 1249 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.91 0.708 – 1.17 0.46 65 656 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.06 0.985 – 1.14 0.118 778 7835 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.06 0.984 – 1.14 0.124 739 7446 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.02 0.784 – 1.32 0.901 56 563 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.12 0.984 – 1.27 0.0871 249 2522 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.987 0.918 – 1.06 0.733 818 8332 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.901 0.772 – 1.05 0.183 179 1810 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.908 0.811 – 1.02 0.0895 343 3542 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.12 0.992 – 1.26 0.0667 301 3042 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.01 0.956 – 1.06 0.77 1537 15454 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.02 0.981 – 1.07 0.275 2266 22955 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.01 0.924 – 1.1 0.847 554 5720 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.01 0.944 – 1.07 0.849 1033 10551 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1 0.906 – 1.11 0.986 442 4497 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.01 0.931 – 1.09 0.821 630 6447 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.988 0.941 – 1.04 0.639 1705 17654 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 1 0.906 – 1.11 0.99 424 4357 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.15 0.924 – 1.42 0.215 83 865 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 1.04 0.872 – 1.25 0.64 129 1312 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.01 0.988 – 1.02 0.55 13520 137647 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1 0.939 – 1.07 0.936 987 10500 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.916 0.744 – 1.13 0.41 98 953 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.01 0.99 – 1.03 0.405 12915 131813 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.982 0.866 – 1.11 0.775 273 2708 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.948 0.823 – 1.09 0.462 208 2042 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.935 0.81 – 1.08 0.359 202 1962 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1 0.901 – 1.11 0.967 365 3773 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 0.986 0.972 – 1 0.0699 19064 181091 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.03 0.988 – 1.07 0.168 2665 26910 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.03 0.905 – 1.18 0.643 228 2327 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.26 1 – 1.58 0.0464 72 756 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.06 0.967 – 1.17 0.21 455 4628 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.13 0.957 – 1.33 0.153 153 1581 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.981 0.965 – 0.996 0.0163 17165 165745 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.97 0.79 – 1.19 0.769 99 1025 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.08 0.935 – 1.24 0.299 198 1974 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.05 0.979 – 1.12 0.188 967 9690 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.04 0.946 – 1.14 0.444 490 4956 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 0.987 0.911 – 1.07 0.748 654 6651 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.924 0.812 – 1.05 0.232 257 2600 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.03 0.931 – 1.14 0.553 399 4066 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.02 0.852 – 1.22 0.84 128 1271 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.06 0.948 – 1.18 0.313 342 3436 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.04 0.986 – 1.1 0.143 1298 13037 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 0.956 0.893 – 1.02 0.19 907 9125 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.97 0.903 – 1.04 0.412 812 8327 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.969 0.898 – 1.04 0.411 727 7455 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.999 0.835 – 1.2 0.995 134 1361 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.995 0.918 – 1.08 0.898 656 6614 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.01 0.865 – 1.17 0.926 179 1802 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.841 0.678 – 1.04 0.116 90 908 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.06 0.938 – 1.21 0.331 255 2563 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.801 0.641 – 1 0.0505 88 887 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.966 0.814 – 1.15 0.69 151 1519 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.97 0.892 – 1.05 0.466 615 6134 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.926 0.792 – 1.08 0.334 173 1726 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.931 0.759 – 1.14 0.489 98 980 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.942 0.742 – 1.2 0.622 74 742 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.03 0.918 – 1.14 0.657 351 3479 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.03 0.925 – 1.15 0.564 350 3469 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 1.04 0.907 – 1.19 0.58 230 2316 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.07 0.928 – 1.23 0.351 201 2023 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1.17 0.998 – 1.38 0.0535 159 1619 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.18 0.996 – 1.39 0.0555 151 1538 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.03 0.838 – 1.27 0.757 101 984 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 1.01 0.845 – 1.21 0.909 139 1442 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.03 0.887 – 1.19 0.706 192 1960 exclusion phecode
260.6 Anorexia Endocrine/metabolic 0.975 0.907 – 1.05 0.499 800 8034 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 0.965 0.908 – 1.03 0.25 1147 11490 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.996 0.923 – 1.08 0.927 728 7267 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.915 0.828 – 1.01 0.0793 420 4257 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.04 0.829 – 1.31 0.726 72 728 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.01 0.879 – 1.15 0.924 224 2303 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.11 0.99 – 1.25 0.0742 330 3297 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.03 0.916 – 1.16 0.607 294 2934 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.03 0.91 – 1.18 0.606 252 2518 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.06 0.912 – 1.24 0.441 184 1844 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1.01 0.828 – 1.22 0.943 107 1093 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.01 0.794 – 1.28 0.937 67 667 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.962 0.815 – 1.14 0.647 153 1545 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.926 0.774 – 1.11 0.401 132 1339 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.998 0.986 – 1.01 0.708 33648 227899 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.998 0.986 – 1.01 0.681 33579 227676 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.996 0.984 – 1.01 0.533 31216 220787 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.09 0.835 – 1.42 0.531 58 570 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.06 0.907 – 1.24 0.453 163 1597 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.07 0.924 – 1.23 0.38 207 2042 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.987 0.954 – 1.02 0.463 3673 36757 exclusion phecode
274.1 Gout Endocrine/metabolic 0.988 0.953 – 1.03 0.535 3137 31394 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.06 0.874 – 1.29 0.549 110 1110 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.977 0.898 – 1.06 0.591 596 5956 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.977 0.895 – 1.07 0.61 543 5425 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.01 0.963 – 1.06 0.711 1956 20480 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 1.03 0.95 – 1.11 0.487 641 6412 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.05 0.939 – 1.17 0.408 350 3620 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.994 0.934 – 1.06 0.84 1079 11629 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.948 0.806 – 1.11 0.516 164 1688 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.02 0.991 – 1.04 0.216 6859 70648 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.02 0.99 – 1.06 0.165 3862 39623 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.03 0.903 – 1.17 0.66 233 2344 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.03 0.978 – 1.08 0.276 1712 17550 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.06 0.99 – 1.13 0.0944 923 9507 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.02 0.967 – 1.08 0.434 1338 13705 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.01 0.952 – 1.08 0.687 1109 11326 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.01 0.949 – 1.08 0.708 1008 10309 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 0.965 0.792 – 1.18 0.727 109 1093 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.02 0.978 – 1.06 0.4 2627 27375 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.02 0.92 – 1.12 0.757 433 4415 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.1 0.916 – 1.32 0.31 124 1234 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 0.974 0.907 – 1.05 0.464 847 8677 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.11 0.993 – 1.24 0.0668 350 3555 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.07 0.932 – 1.22 0.356 226 2240 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.05 0.792 – 1.4 0.723 51 509 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.969 0.95 – 0.989 0.0027 10280 104821 exclusion phecode
278.1 Obesity Endocrine/metabolic 0.971 0.951 – 0.991 0.00445 10127 103273 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 0.858 0.675 – 1.09 0.212 75 804 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.742 0.571 – 0.965 0.026 65 634 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.875 0.763 – 1 0.0574 239 2427 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 0.88 0.758 – 1.02 0.0912 203 2032 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.871 0.727 – 1.04 0.136 134 1331 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 0.925 0.811 – 1.05 0.245 244 2455 exclusion phecode
280 Iron deficiency anemias Hematopoietic 0.991 0.967 – 1.01 0.443 7300 73421 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.988 0.964 – 1.01 0.332 7021 70520 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.05 0.949 – 1.15 0.363 427 4366 exclusion phecode
281 Other deficiency anemia Hematopoietic 1 0.939 – 1.06 0.991 1061 10695 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 0.995 0.933 – 1.06 0.869 1016 10246 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.01 0.939 – 1.09 0.743 711 7206 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.92 0.786 – 1.08 0.298 170 1710 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 0.931 0.8 – 1.08 0.354 178 1775 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.06 0.811 – 1.4 0.652 51 525 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.07 0.901 – 1.27 0.439 141 1459 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.947 0.752 – 1.19 0.642 82 823 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.06 0.885 – 1.26 0.547 131 1329 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.09 0.889 – 1.34 0.407 100 1031 exclusion phecode
284 Aplastic anemia Hematopoietic 0.969 0.875 – 1.07 0.538 411 4245 exclusion phecode
285 Other anemias Hematopoietic 0.99 0.972 – 1.01 0.33 11381 116882 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.885 0.776 – 1.01 0.0722 247 2611 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.07 0.984 – 1.16 0.114 605 6738 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.06 0.951 – 1.19 0.285 333 4002 exclusion phecode
286 Coagulation defects Hematopoietic 1.06 0.991 – 1.14 0.0889 870 8954 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.999 0.905 – 1.1 0.991 434 4452 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.852 0.683 – 1.06 0.156 88 927 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.04 0.918 – 1.18 0.547 280 2851 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.17 0.885 – 1.54 0.273 59 617 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.3 1.04 – 1.61 0.0207 85 843 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.14 1.02 – 1.27 0.0193 360 3754 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.978 0.928 – 1.03 0.41 1554 16086 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.904 0.751 – 1.09 0.289 125 1247 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 0.986 0.934 – 1.04 0.604 1458 15123 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.01 0.915 – 1.13 0.78 401 4058 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.04 0.819 – 1.32 0.745 71 736 exclusion phecode
288 Diseases of white blood cells Hematopoietic 0.986 0.949 – 1.02 0.481 2801 36328 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 0.987 0.945 – 1.03 0.545 2252 30535 exclusion phecode
288.11 Neutropenia Hematopoietic 0.986 0.945 – 1.03 0.522 2259 30604 exclusion phecode
288.3 Eosinophilia Hematopoietic 1.13 0.891 – 1.44 0.309 68 692 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.965 0.898 – 1.04 0.34 825 8353 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.894 0.789 – 1.01 0.0772 275 2799 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.03 0.985 – 1.07 0.204 2365 25341 exclusion phecode
289.5 Diseases of spleen Hematopoietic 0.942 0.858 – 1.03 0.213 491 4991 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 0.96 0.847 – 1.09 0.519 286 2877 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 0.99 0.797 – 1.23 0.931 87 878 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.01 0.967 – 1.06 0.556 1830 18642 exclusion phecode
290.1 Dementias Mental Disorders 1 0.936 – 1.07 0.995 952 9666 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.996 0.899 – 1.1 0.933 402 4115 exclusion phecode
290.16 Vascular dementia Mental Disorders 0.904 0.779 – 1.05 0.184 198 1958 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.03 0.952 – 1.12 0.439 622 6316 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.998 0.785 – 1.27 0.986 69 700 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.948 0.882 – 1.02 0.144 806 8148 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.07 0.888 – 1.28 0.486 128 1283 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.954 0.844 – 1.08 0.448 280 2780 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 0.919 0.832 – 1.02 0.101 416 4258 exclusion phecode
292 Neurological disorders Mental Disorders 1.02 0.986 – 1.05 0.281 4419 44886 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.99 0.938 – 1.04 0.716 1436 14647 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.912 0.783 – 1.06 0.232 186 1857 exclusion phecode
292.3 Memory loss Mental Disorders 1.06 0.978 – 1.14 0.163 672 6772 exclusion phecode
292.4 Altered mental status Mental Disorders 1.03 0.983 – 1.08 0.219 2077 21189 exclusion phecode
292.6 Hallucinations Mental Disorders 1.02 0.907 – 1.15 0.746 297 2975 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.01 0.966 – 1.06 0.644 2052 20446 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.973 0.907 – 1.04 0.444 853 8740 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.1 1.02 – 1.18 0.0117 815 8254 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.05 0.962 – 1.14 0.281 556 5660 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.23 1.06 – 1.43 0.00691 169 1732 exclusion phecode
295.3 Psychosis Mental Disorders 1.16 0.99 – 1.35 0.066 167 1664 exclusion phecode
296 Mood disorders Mental Disorders 0.985 0.967 – 1 0.126 11748 119692 exclusion phecode
296.1 Bipolar Mental Disorders 1 0.941 – 1.07 0.901 1015 10309 exclusion phecode
296.2 Depression Mental Disorders 0.982 0.964 – 1 0.0761 11133 113508 exclusion phecode
296.22 Major depressive disorder Mental Disorders 0.955 0.856 – 1.07 0.415 349 3472 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.894 0.794 – 1.01 0.0672 299 2966 exclusion phecode
300 Anxiety disorders Mental Disorders 1 0.978 – 1.03 0.774 6464 66182 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.01 0.98 – 1.03 0.644 5961 61101 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 1.05 0.887 – 1.25 0.557 143 1453 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.976 0.901 – 1.06 0.56 669 6839 exclusion phecode
300.13 Phobia Mental Disorders 0.92 0.835 – 1.01 0.0899 464 4821 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.991 0.829 – 1.19 0.925 139 1371 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.03 0.859 – 1.23 0.762 119 1210 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.02 0.853 – 1.23 0.795 113 1101 exclusion phecode
301 Personality disorders Mental Disorders 1.07 0.956 – 1.2 0.24 321 3254 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.977 0.805 – 1.18 0.812 113 1147 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 0.943 0.833 – 1.07 0.355 283 2836 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.988 0.896 – 1.09 0.813 450 4516 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.94 0.84 – 1.05 0.279 336 3398 exclusion phecode
303.4 Somatoform disorder Mental Disorders 1.22 1.01 – 1.47 0.0424 119 1183 exclusion phecode
304 Adjustment reaction Mental Disorders 1.09 0.964 – 1.23 0.175 279 2852 exclusion phecode
305.2 Eating disorder Mental Disorders 0.983 0.792 – 1.22 0.88 87 874 exclusion phecode
306 Other mental disorder Mental Disorders 0.997 0.984 – 1.01 0.645 26720 223406 exclusion phecode
306.9 Tension headache Mental Disorders 1.02 0.911 – 1.15 0.707 305 3053 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.856 0.679 – 1.08 0.19 73 761 exclusion phecode
313.3 Autism Mental Disorders 0.808 0.611 – 1.07 0.135 51 535 exclusion phecode
315 Develomental delays and disorders Mental Disorders 0.987 0.884 – 1.1 0.811 342 3419 exclusion phecode
315.1 Learning disorder Mental Disorders 1.24 1.06 – 1.45 0.00706 159 1580 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.963 0.779 – 1.19 0.732 87 864 exclusion phecode
316 Substance addiction and disorders Mental Disorders 0.998 0.97 – 1.03 0.896 5205 52399 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1 0.984 – 1.02 0.815 12362 124405 exclusion phecode
317.1 Alcoholism Mental Disorders 1.01 0.987 – 1.03 0.413 8637 87062 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.05 0.982 – 1.13 0.143 822 8297 exclusion phecode
318 Tobacco use disorder Mental Disorders 1 0.985 – 1.01 0.969 18601 181065 exclusion phecode
320 Meningitis Neurological 1.08 0.975 – 1.19 0.145 432 4318 exclusion phecode
323 Encephalitis Neurological 1.05 0.937 – 1.18 0.402 327 3323 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 0.898 0.698 – 1.16 0.403 70 714 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.02 0.903 – 1.15 0.741 281 2812 exclusion phecode
327 Sleep disorders Neurological 1 0.944 – 1.07 0.922 1142 11427 exclusion phecode
327.3 Sleep apnea Neurological 1.01 0.975 – 1.04 0.718 4346 43580 exclusion phecode
327.4 Insomnia Neurological 0.961 0.817 – 1.13 0.634 159 1612 exclusion phecode
327.41 Organic or persistent insomnia Neurological 0.955 0.799 – 1.14 0.615 133 1347 exclusion phecode
331 Other cerebral degenerations Neurological 1.05 0.984 – 1.11 0.148 1088 11048 exclusion phecode
331.1 Hydrocephalus Neurological 0.974 0.886 – 1.07 0.586 471 4812 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.13 1.02 – 1.25 0.0171 415 4183 exclusion phecode
332 Parkinson's disease Neurological 1.01 0.954 – 1.08 0.65 1088 10941 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.971 0.905 – 1.04 0.4 867 8601 exclusion phecode
333.1 Essential tremor Neurological 1.02 0.889 – 1.18 0.742 209 2069 exclusion phecode
333.2 Myoclonus Neurological 0.867 0.703 – 1.07 0.186 95 936 exclusion phecode
333.4 Torsion dystonia Neurological 0.93 0.815 – 1.06 0.279 243 2417 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.05 0.999 – 1.1 0.0537 1714 17666 exclusion phecode
334.1 Spinocerebellar disease Neurological 0.946 0.78 – 1.15 0.572 110 1137 exclusion phecode
334.2 Anterior horn cell disease Neurological 1.07 0.942 – 1.22 0.287 236 2370 exclusion phecode
335 Multiple sclerosis Neurological 0.992 0.936 – 1.05 0.78 1274 12847 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.07 0.943 – 1.22 0.292 256 2584 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 0.981 0.769 – 1.25 0.875 70 700 exclusion phecode
338 Pain Neurological 1.04 0.966 – 1.12 0.295 718 7414 exclusion phecode
338.1 Acute pain Neurological 1.04 0.933 – 1.15 0.496 362 3815 exclusion phecode
338.2 Chronic pain Neurological 1.02 0.916 – 1.13 0.728 362 3666 exclusion phecode
339 Other headache syndromes Neurological 1.02 0.993 – 1.04 0.162 7463 75424 exclusion phecode
340 Migraine Neurological 1.02 0.976 – 1.06 0.458 2714 27423 exclusion phecode
340.1 Migrain with aura Neurological 1.24 1.07 – 1.42 0.00303 202 2041 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.988 0.866 – 1.13 0.858 244 2464 exclusion phecode
342 Hemiplegia Neurological 0.957 0.906 – 1.01 0.106 1446 14540 exclusion phecode
343 Infantile cerebral palsy Neurological 1 0.849 – 1.19 0.964 143 1415 exclusion phecode
344 Other paralytic syndromes Neurological 0.948 0.874 – 1.03 0.196 632 6437 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.02 0.986 – 1.05 0.32 4840 48885 exclusion phecode
345.1 Epilepsy Neurological 1.04 0.969 – 1.12 0.276 841 8425 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.14 1.04 – 1.26 0.00773 428 4271 exclusion phecode
345.12 Partial epilepsy Neurological 1.04 0.918 – 1.18 0.53 267 2686 exclusion phecode
345.3 Convulsions Neurological 0.99 0.947 – 1.03 0.65 2142 21744 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.21 1.01 – 1.45 0.0383 131 1398 exclusion phecode
348 Other conditions of brain Neurological 1.05 0.977 – 1.14 0.176 745 7607 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 0.983 0.86 – 1.12 0.801 251 2586 exclusion phecode
348.4 Cerebral cysts Neurological 1.16 0.972 – 1.38 0.101 128 1308 exclusion phecode
348.7 Coma Neurological 0.948 0.847 – 1.06 0.352 345 3492 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.04 0.914 – 1.18 0.555 239 2449 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 0.99 0.89 – 1.1 0.849 372 3792 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.1 0.985 – 1.24 0.0885 325 3287 exclusion phecode
350 Abnormal movement Neurological 1.03 0.989 – 1.07 0.15 2536 25904 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.07 0.994 – 1.14 0.0734 845 8588 exclusion phecode
350.2 Abnormality of gait Neurological 1.02 0.972 – 1.08 0.36 1502 15466 exclusion phecode
350.3 Lack of coordination Neurological 1.02 0.914 – 1.14 0.718 353 3531 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.924 0.704 – 1.21 0.566 54 522 exclusion phecode
351 Other peripheral nerve disorders Neurological 0.994 0.975 – 1.01 0.509 11866 119214 exclusion phecode
352 Disorders of other cranial nerves Neurological 0.99 0.935 – 1.05 0.719 1315 13219 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.992 0.902 – 1.09 0.867 445 4471 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 0.999 0.93 – 1.07 0.968 846 8492 exclusion phecode
353 Nerve root and plexus disorders Neurological 0.986 0.926 – 1.05 0.649 1067 10922 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.979 0.807 – 1.19 0.831 106 1098 exclusion phecode
353.2 Nerve root lesions Neurological 0.896 0.687 – 1.17 0.417 56 546 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.06 0.9 – 1.25 0.48 149 1489 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.02 0.963 – 1.08 0.493 1282 13335 exclusion phecode
358 Myoneural disorders Neurological 1.12 0.971 – 1.29 0.122 202 2047 exclusion phecode
358.1 Myasthenia gravis Neurological 1.07 0.923 – 1.24 0.366 183 1863 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 1.09 0.99 – 1.2 0.08 440 4493 exclusion phecode
359.1 Muscular dystrophies Neurological 1.25 1.04 – 1.51 0.0201 119 1185 exclusion phecode
359.2 Myopathy Neurological 1.04 0.932 – 1.16 0.488 337 3474 exclusion phecode
360 Disorders of the globe Sense Organs 0.996 0.888 – 1.12 0.947 325 3255 exclusion phecode
360.2 Progressive myopia Sense Organs 1.09 0.954 – 1.24 0.21 241 2416 exclusion phecode
361 Retinal detachments and defects Sense Organs 1.03 0.996 – 1.07 0.0806 3146 31583 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.03 0.972 – 1.09 0.342 1355 13554 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 1.02 0.8 – 1.29 0.885 67 660 exclusion phecode
362 Other retinal disorders Sense Organs 1.01 0.972 – 1.04 0.735 3649 36924 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1 0.956 – 1.05 0.987 2057 20817 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1 0.957 – 1.05 0.966 2054 20788 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.23 1.04 – 1.45 0.0135 155 1558 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1.37 1.11 – 1.68 0.00315 96 957 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.02 0.948 – 1.1 0.606 814 8244 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 1.26 1.08 – 1.47 0.00273 174 1782 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.929 0.733 – 1.18 0.543 80 787 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.748 0.614 – 0.912 0.00401 116 1123 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.16 0.991 – 1.35 0.0647 164 1640 exclusion phecode
363.3 Chorioretinal scars Sense Organs 1.13 0.892 – 1.43 0.314 67 673 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.923 0.849 – 1 0.0587 623 6236 exclusion phecode
364.1 Corneal opacity Sense Organs 1.03 0.822 – 1.29 0.804 87 886 exclusion phecode
364.2 Corneal edema Sense Organs 0.869 0.69 – 1.09 0.233 76 771 exclusion phecode
364.4 Corneal degenerations Sense Organs 0.927 0.8 – 1.07 0.312 199 1952 exclusion phecode
364.41 Keratoconus Sense Organs 0.928 0.742 – 1.16 0.512 86 856 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.925 0.797 – 1.07 0.305 199 2011 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.751 0.606 – 0.93 0.00867 97 967 exclusion phecode
365 Glaucoma Sense Organs 1.03 0.998 – 1.06 0.069 4223 42542 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 1.03 0.965 – 1.1 0.38 997 9987 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 1.03 0.962 – 1.1 0.419 992 9927 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.04 0.958 – 1.12 0.361 662 6688 exclusion phecode
366 Cataract Sense Organs 1 0.988 – 1.02 0.686 19091 162354 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 1.08 0.841 – 1.38 0.55 67 681 exclusion phecode
366.2 Senile cataract Sense Organs 0.992 0.969 – 1.01 0.475 7874 78514 exclusion phecode
366.3 Traumatic cataract Sense Organs 1 0.816 – 1.23 0.982 101 1006 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.04 0.997 – 1.09 0.0665 2319 23161 exclusion phecode
367.1 Myopia Sense Organs 1.02 0.966 – 1.09 0.416 1202 12023 exclusion phecode
367.2 Astigmatism Sense Organs 1.16 0.999 – 1.36 0.0523 179 1815 exclusion phecode
367.8 Hypermetropia Sense Organs 0.983 0.862 – 1.12 0.798 248 2414 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.03 0.957 – 1.12 0.397 695 6950 exclusion phecode
368 Visual disturbances Sense Organs 1.01 0.969 – 1.05 0.723 2809 28635 exclusion phecode
368.1 Amblyopia Sense Organs 0.987 0.901 – 1.08 0.781 512 5093 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.982 0.908 – 1.06 0.64 691 7085 exclusion phecode
368.3 Anisometropia Sense Organs 0.973 0.823 – 1.15 0.745 145 1493 exclusion phecode
368.4 Visual field defects Sense Organs 1.03 0.924 – 1.16 0.565 323 3242 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.988 0.907 – 1.08 0.781 574 5907 exclusion phecode
369 Infection of the eye Sense Organs 1.01 0.92 – 1.1 0.88 532 5342 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.89 0.736 – 1.07 0.225 119 1199 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 1.04 0.894 – 1.2 0.636 205 2046 exclusion phecode
370 Keratitis Sense Organs 0.973 0.862 – 1.1 0.663 277 2765 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.925 0.781 – 1.1 0.366 136 1366 exclusion phecode
371 Inflammation of the eye Sense Organs 1.02 0.982 – 1.06 0.298 2932 29507 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.05 0.959 – 1.16 0.274 467 4670 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 1.01 0.966 – 1.05 0.696 2263 22829 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.03 0.96 – 1.12 0.371 731 7347 exclusion phecode
374 Other disorders of eyelids Sense Organs 1.01 0.978 – 1.03 0.665 5466 54729 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.975 0.915 – 1.04 0.446 1030 10339 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.994 0.946 – 1.04 0.809 1751 17480 exclusion phecode
375 Disorders of lacrimal system Sense Organs 1.03 0.982 – 1.07 0.241 2091 21043 exclusion phecode
375.2 Epiphora Sense Organs 0.967 0.901 – 1.04 0.362 850 8549 exclusion phecode
376 Disorders of the orbit Sense Organs 0.878 0.708 – 1.09 0.238 84 831 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.898 0.802 – 1 0.0604 342 3486 exclusion phecode
377.1 Optic atrophy Sense Organs 0.955 0.735 – 1.24 0.727 54 557 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.971 0.805 – 1.17 0.755 118 1202 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.02 0.963 – 1.08 0.542 1364 13671 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.01 0.947 – 1.09 0.685 877 8789 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.966 0.838 – 1.11 0.639 208 2091 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.01 0.888 – 1.14 0.905 264 2674 exclusion phecode
379 Other disorders of eye Sense Organs 0.986 0.953 – 1.02 0.437 3542 35724 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.935 0.883 – 0.99 0.0221 1304 13189 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.977 0.929 – 1.03 0.361 1725 17435 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 0.941 0.729 – 1.21 0.639 66 687 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.06 0.952 – 1.17 0.296 385 3906 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.04 0.888 – 1.23 0.604 158 1636 exclusion phecode
380 Disorders of external ear Sense Organs 0.972 0.895 – 1.06 0.505 626 6239 exclusion phecode
380.1 Otitis externa Sense Organs 0.982 0.895 – 1.08 0.709 495 4958 exclusion phecode
380.4 Impacted cerumen Sense Organs 0.995 0.892 – 1.11 0.928 350 3491 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.995 0.951 – 1.04 0.839 2071 20775 exclusion phecode
381.1 Otitis media Sense Organs 1.01 0.958 – 1.06 0.778 1704 17086 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1 0.931 – 1.08 0.992 821 8256 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 1 0.867 – 1.16 0.951 184 1867 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.884 0.749 – 1.04 0.143 164 1654 exclusion phecode
381.9 Otorrhea Sense Organs 1.03 0.908 – 1.17 0.641 270 2721 exclusion phecode
382 Otalgia Sense Organs 0.983 0.87 – 1.11 0.778 285 2967 exclusion phecode
383 Otosclerosis Sense Organs 0.922 0.817 – 1.04 0.183 298 3002 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 0.974 0.919 – 1.03 0.375 1259 12587 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 0.973 0.912 – 1.04 0.413 1004 10104 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.944 0.876 – 1.02 0.134 757 7610 exclusion phecode
385.3 Cholesteatoma Sense Organs 1 0.918 – 1.09 0.998 585 5911 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.814 0.709 – 0.934 0.00332 236 2332 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1 0.95 – 1.05 0.986 1660 16731 exclusion phecode
386.1 Meniere's disease Sense Organs 0.98 0.897 – 1.07 0.664 542 5534 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.942 0.844 – 1.05 0.29 360 3615 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.03 0.956 – 1.11 0.427 741 7417 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.991 0.961 – 1.02 0.582 4374 44351 exclusion phecode
388 Other disorders of ear Sense Organs 1.04 0.902 – 1.21 0.569 195 1949 exclusion phecode
389 Hearing loss Sense Organs 0.996 0.964 – 1.03 0.814 4031 40600 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.939 0.851 – 1.04 0.206 442 4399 exclusion phecode
389.2 Conductive hearing loss Sense Organs 0.977 0.886 – 1.08 0.639 440 4341 exclusion phecode
389.4 Tinnitus Sense Organs 1.06 0.963 – 1.16 0.243 498 4996 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.02 0.988 – 1.05 0.235 4726 47679 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.04 0.998 – 1.08 0.0666 2882 29085 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.01 0.952 – 1.07 0.775 1240 12506 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 0.991 0.929 – 1.06 0.781 1020 10246 exclusion phecode
395 Heart valve disorders Circulatory System 1.03 0.999 – 1.07 0.0537 4067 41116 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.03 0.992 – 1.07 0.116 2781 28107 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.955 0.844 – 1.08 0.467 268 2708 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.04 0.845 – 1.27 0.723 100 1024 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.91 0.738 – 1.12 0.375 97 946 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.03 0.98 – 1.09 0.216 1448 14596 exclusion phecode
396 Abnormal heart sounds Circulatory System 0.991 0.928 – 1.06 0.778 974 10029 exclusion phecode
401 Hypertension Circulatory System 0.989 0.981 – 0.998 0.0155 70777 259204 exclusion phecode
401.1 Essential hypertension Circulatory System 0.989 0.981 – 0.998 0.0142 70560 258992 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1 0.954 – 1.05 0.962 1832 18570 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.07 0.967 – 1.19 0.181 362 3632 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.981 0.93 – 1.03 0.476 1484 15097 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.07 0.904 – 1.26 0.433 138 1401 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1 0.948 – 1.06 0.953 1415 14377 exclusion phecode
411 Ischemic Heart Disease Circulatory System 0.995 0.983 – 1.01 0.395 30497 204338 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.973 0.945 – 1 0.0624 5029 50315 exclusion phecode
411.2 Myocardial infarction Circulatory System 0.999 0.98 – 1.02 0.908 11737 110723 exclusion phecode
411.3 Angina pectoris Circulatory System 0.999 0.983 – 1.02 0.923 15474 139847 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 0.993 0.979 – 1.01 0.378 19828 151239 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.958 0.885 – 1.04 0.291 681 6839 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.992 0.975 – 1.01 0.366 14926 128684 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.928 0.874 – 0.986 0.016 1193 11937 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 0.979 0.932 – 1.03 0.395 1761 17912 exclusion phecode
414.2 ASCVD Circulatory System 1.09 0.845 – 1.4 0.514 69 710 exclusion phecode
415 Pulmonary heart disease Circulatory System 0.994 0.963 – 1.03 0.697 4201 43500 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.821 0.643 – 1.05 0.113 72 714 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.03 0.942 – 1.12 0.555 583 5812 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.04 0.945 – 1.15 0.412 433 4320 exclusion phecode
416 Cardiomegaly Circulatory System 0.982 0.943 – 1.02 0.385 2604 26175 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.01 0.997 – 1.02 0.155 27547 261731 exclusion phecode
418.1 Precordial pain Circulatory System 0.988 0.954 – 1.02 0.491 3424 34403 exclusion phecode
420 Carditis Circulatory System 0.982 0.938 – 1.03 0.435 2013 20517 exclusion phecode
420.1 Myocarditis Circulatory System 0.918 0.76 – 1.11 0.372 125 1241 exclusion phecode
420.2 Pericarditis Circulatory System 0.986 0.931 – 1.05 0.646 1271 13034 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.05 0.909 – 1.2 0.533 220 2178 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.02 0.84 – 1.25 0.809 109 1103 exclusion phecode
420.3 Endocarditis Circulatory System 0.968 0.896 – 1.05 0.413 695 7007 exclusion phecode
425 Cardiomyopathy Circulatory System 1.04 0.981 – 1.1 0.186 1224 12422 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.04 0.984 – 1.11 0.158 1191 12079 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.13 0.942 – 1.35 0.19 129 1294 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.973 0.827 – 1.15 0.741 160 1576 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 0.921 0.71 – 1.19 0.533 59 598 exclusion phecode
426 Cardiac conduction disorders Circulatory System 0.989 0.965 – 1.01 0.405 6708 67513 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.02 0.972 – 1.06 0.474 2059 20756 exclusion phecode
426.21 First degree AV block Circulatory System 0.998 0.933 – 1.07 0.945 967 9692 exclusion phecode
426.23 Second degree AV block Circulatory System 1.02 0.923 – 1.12 0.73 441 4452 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1.02 0.936 – 1.11 0.662 567 5744 exclusion phecode
426.25 Other heart block Circulatory System 1.1 0.922 – 1.32 0.286 126 1284 exclusion phecode
426.3 Bundle branch block Circulatory System 1.01 0.976 – 1.05 0.531 3236 32524 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.01 0.953 – 1.06 0.846 1452 14624 exclusion phecode
426.32 Left bundle branch block Circulatory System 0.999 0.95 – 1.05 0.96 1691 17005 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.884 0.773 – 1.01 0.0727 223 2279 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 0.93 0.711 – 1.22 0.595 57 578 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.994 0.953 – 1.04 0.771 2406 24220 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.998 0.956 – 1.04 0.944 2209 22248 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 0.993 0.979 – 1.01 0.285 23323 199753 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 0.984 0.949 – 1.02 0.404 3081 31117 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.993 0.951 – 1.04 0.734 2238 22715 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.964 0.9 – 1.03 0.29 921 9222 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 0.99 0.973 – 1.01 0.241 14182 130160 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.993 0.957 – 1.03 0.689 3124 31519 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.971 0.914 – 1.03 0.345 1157 11660 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.984 0.881 – 1.1 0.772 333 3385 exclusion phecode
427.42 Cardiac arrest Circulatory System 0.962 0.9 – 1.03 0.26 962 9666 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.922 0.861 – 0.988 0.021 910 9269 exclusion phecode
427.6 Premature beats Circulatory System 0.985 0.902 – 1.08 0.74 517 5209 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1.01 0.841 – 1.22 0.895 116 1144 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.01 0.965 – 1.06 0.679 2046 21135 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.965 0.869 – 1.07 0.512 388 3909 exclusion phecode
427.9 Palpitations Circulatory System 1.01 0.977 – 1.05 0.553 3619 36633 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.996 0.968 – 1.02 0.764 5422 54810 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 0.968 0.925 – 1.01 0.158 2044 20589 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.01 0.982 – 1.05 0.421 4315 43620 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.07 0.988 – 1.15 0.0989 696 6961 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.07 0.829 – 1.37 0.616 61 629 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.07 0.972 – 1.17 0.175 512 5079 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.08 0.929 – 1.24 0.332 186 1903 exclusion phecode
430 Intracranial hemorrhage Circulatory System 0.979 0.932 – 1.03 0.38 1822 18251 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.979 0.911 – 1.05 0.573 811 8034 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 0.934 0.865 – 1.01 0.0826 740 7448 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.01 0.895 – 1.15 0.832 256 2607 exclusion phecode
433 Cerebrovascular disease Circulatory System 0.975 0.953 – 0.997 0.0255 8468 85012 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.949 0.893 – 1.01 0.0914 1156 11533 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 0.975 0.849 – 1.12 0.726 220 2191 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.968 0.937 – 0.999 0.0436 4116 41271 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.978 0.929 – 1.03 0.384 1630 16369 exclusion phecode
433.3 Cerebral ischemia Circulatory System 0.986 0.949 – 1.03 0.478 2792 28132 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 0.979 0.936 – 1.02 0.348 2074 20748 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 0.915 0.822 – 1.02 0.107 370 3768 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.951 0.898 – 1.01 0.0918 1236 12427 exclusion phecode
440 Atherosclerosis Circulatory System 1.03 0.974 – 1.09 0.304 1354 13535 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.927 0.769 – 1.12 0.426 111 1105 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.03 0.96 – 1.11 0.382 788 7931 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.08 0.954 – 1.21 0.235 281 2769 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 0.885 0.812 – 0.964 0.00522 580 5919 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.844 0.742 – 0.959 0.00917 268 2717 exclusion phecode
442 Other aneurysm Circulatory System 0.975 0.929 – 1.02 0.302 1854 18693 exclusion phecode
442.1 Aortic aneurysm Circulatory System 0.991 0.939 – 1.05 0.756 1433 14448 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.98 0.915 – 1.05 0.548 921 9268 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 0.903 0.736 – 1.11 0.328 102 1012 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.948 0.812 – 1.11 0.499 165 1670 exclusion phecode
442.4 Arterial dissection Circulatory System 1.12 0.844 – 1.48 0.441 53 536 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 0.902 0.776 – 1.05 0.182 195 1970 exclusion phecode
443 Peripheral vascular disease Circulatory System 0.997 0.965 – 1.03 0.878 3814 38197 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 0.995 0.935 – 1.06 0.865 1094 10916 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.97 0.875 – 1.08 0.562 381 3817 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 0.994 0.96 – 1.03 0.717 3582 35877 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.996 0.956 – 1.04 0.833 2522 25320 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.01 0.944 – 1.08 0.764 898 9082 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.977 0.896 – 1.07 0.609 543 5467 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.03 0.959 – 1.11 0.404 786 7907 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 1 0.864 – 1.17 0.962 186 1826 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.05 0.942 – 1.16 0.393 365 3676 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.01 0.886 – 1.16 0.865 234 2335 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1 0.947 – 1.06 0.945 1301 13049 exclusion phecode
447.1 Stricture of artery Circulatory System 1.03 0.963 – 1.11 0.371 857 8557 exclusion phecode
448 Disease of capillaries Circulatory System 1.08 0.905 – 1.28 0.407 135 1365 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1 0.916 – 1.09 0.981 526 6739 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.995 0.962 – 1.03 0.763 3733 38577 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.993 0.959 – 1.03 0.706 3501 35961 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1.05 0.955 – 1.14 0.334 519 5468 exclusion phecode
454 Varicose veins Circulatory System 0.997 0.977 – 1.02 0.731 10698 107824 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1 0.981 – 1.02 1 10982 110692 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.972 0.893 – 1.06 0.508 593 6151 exclusion phecode
455 Hemorrhoids Circulatory System 0.988 0.975 – 1 0.0955 22689 227493 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.919 0.781 – 1.08 0.306 176 1820 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.04 0.838 – 1.28 0.742 94 938 exclusion phecode
458 Hypotension Circulatory System 0.995 0.968 – 1.02 0.739 5469 55972 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.04 0.98 – 1.1 0.207 1279 12991 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 0.933 0.813 – 1.07 0.321 228 2272 exclusion phecode
458.9 Hypotension NOS Circulatory System 0.986 0.952 – 1.02 0.446 3292 33918 exclusion phecode
459 Other disorders of circulatory system Circulatory System 0.99 0.974 – 1.01 0.227 15433 155978 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 0.979 0.818 – 1.17 0.822 132 1381 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 0.99 0.973 – 1.01 0.213 15281 154653 exclusion phecode
464 Acute sinusitis Respiratory 0.909 0.781 – 1.06 0.216 187 1877 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.01 0.963 – 1.05 0.746 2061 22070 exclusion phecode
465.2 Acute pharyngitis Respiratory 1.01 0.935 – 1.09 0.827 735 8102 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.04 0.889 – 1.22 0.611 159 1594 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.01 0.976 – 1.04 0.675 4558 45576 exclusion phecode
471 Nasal polyps Respiratory 0.996 0.961 – 1.03 0.848 3227 32267 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.03 0.965 – 1.11 0.345 926 9326 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 0.999 0.959 – 1.04 0.967 2463 24728 exclusion phecode
473.1 Chronic laryngitis Respiratory 0.929 0.756 – 1.14 0.484 103 1009 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.955 0.838 – 1.09 0.485 245 2562 exclusion phecode
473.4 Voice disturbance Respiratory 1.03 0.965 – 1.1 0.384 1038 10425 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 0.977 0.93 – 1.03 0.357 1730 17289 exclusion phecode
474.1 Acute tonsillitis Respiratory 0.958 0.876 – 1.05 0.343 529 5351 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.995 0.935 – 1.06 0.886 1097 10892 exclusion phecode
475 Chronic sinusitis Respiratory 1.01 0.965 – 1.05 0.797 2507 25089 exclusion phecode
476 Allergic rhinitis Respiratory 0.943 0.884 – 1.01 0.0788 1016 10228 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 0.998 0.956 – 1.04 0.919 2354 23801 exclusion phecode
478 Throat pain Respiratory 0.935 0.838 – 1.04 0.232 361 3647 exclusion phecode
479 Other upper respiratory disease Respiratory 1 0.971 – 1.04 0.865 3960 39639 exclusion phecode
480 Pneumonia Respiratory 1.03 1.01 – 1.05 0.0129 9840 100504 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.03 1 – 1.05 0.0473 6295 64486 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.02 0.995 – 1.05 0.115 5576 57104 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.05 0.843 – 1.31 0.665 87 904 exclusion phecode
480.2 Viral pneumonia Respiratory 0.759 0.587 – 0.981 0.0349 69 696 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.05 0.85 – 1.29 0.676 95 965 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.02 0.946 – 1.1 0.619 756 7735 exclusion phecode
481 Influenza Respiratory 0.927 0.826 – 1.04 0.2 315 3184 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 1 0.862 – 1.16 0.985 184 1863 exclusion phecode
495 Asthma Respiratory 0.994 0.981 – 1.01 0.369 24392 241857 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.05 0.923 – 1.2 0.453 240 2423 exclusion phecode
496 Chronic airway obstruction Respiratory 1.01 0.989 – 1.03 0.353 9951 98445 exclusion phecode
496.1 Emphysema Respiratory 0.978 0.929 – 1.03 0.385 1660 16988 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.06 1.02 – 1.11 0.0015 2828 28583 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.06 1.02 – 1.11 0.00243 2596 26267 exclusion phecode
496.3 Bronchiectasis Respiratory 0.997 0.95 – 1.05 0.899 1779 18136 exclusion phecode
497 Bronchitis Respiratory 1.06 0.979 – 1.15 0.147 599 6054 exclusion phecode
500 Lung disease due to external agents Respiratory 1.05 0.946 – 1.16 0.369 395 4038 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.08 0.862 – 1.36 0.499 79 758 exclusion phecode
500.2 Pneumoconiosis Respiratory 1.08 0.944 – 1.23 0.272 241 2398 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1 0.925 – 1.09 0.935 633 6423 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1 0.936 – 1.07 0.943 882 8939 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 0.955 0.87 – 1.05 0.34 489 4921 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.971 0.865 – 1.09 0.624 317 3176 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 0.936 0.72 – 1.22 0.624 59 586 exclusion phecode
506 Empyema and pneumothorax Respiratory 0.981 0.922 – 1.04 0.558 1075 11107 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.01 0.987 – 1.04 0.333 5996 62505 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.06 1.02 – 1.12 0.00858 1897 19342 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.04 0.994 – 1.08 0.0978 2493 25256 exclusion phecode
509.1 Respiratory failure Respiratory 1.05 1 – 1.1 0.0336 1975 20083 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.05 0.997 – 1.1 0.0633 1722 17547 exclusion phecode
509.5 Respiratory arrest Respiratory 0.946 0.796 – 1.12 0.529 141 1382 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.941 0.847 – 1.05 0.257 380 3743 exclusion phecode
510 Other diseases of lung Respiratory 0.979 0.907 – 1.06 0.593 703 7327 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1 0.982 – 1.03 0.752 8526 87384 exclusion phecode
512.1 Wheezing Respiratory 1.01 0.879 – 1.16 0.907 211 2129 exclusion phecode
512.2 Painful respiration Respiratory 0.905 0.779 – 1.05 0.195 191 1995 exclusion phecode
512.7 Shortness of breath Respiratory 1.02 0.993 – 1.05 0.15 5517 56563 exclusion phecode
512.8 Cough Respiratory 0.975 0.937 – 1.01 0.21 2706 27660 exclusion phecode
512.9 Other dyspnea Respiratory 0.973 0.907 – 1.04 0.441 879 8878 exclusion phecode
513 Respiratory abnormalities Respiratory 0.974 0.896 – 1.06 0.531 587 5963 exclusion phecode
513.3 Hypoventilation Respiratory 0.792 0.625 – 1 0.0521 77 809 exclusion phecode
513.4 Hyperventilation Respiratory 1.06 0.936 – 1.2 0.368 265 2680 exclusion phecode
513.8 Disorders of diaphragm Respiratory 0.96 0.809 – 1.14 0.636 150 1518 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.01 0.971 – 1.06 0.562 2281 23883 exclusion phecode
516 Abnormal sputum Respiratory 1 0.957 – 1.05 0.971 2054 20778 exclusion phecode
516.1 Hemoptysis Respiratory 1 0.956 – 1.05 0.955 1996 20201 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.992 0.97 – 1.01 0.448 8840 90880 exclusion phecode
519.2 Respiratory complications Respiratory 1.06 0.939 – 1.19 0.361 304 3159 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.993 0.971 – 1.02 0.551 8381 85909 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.987 0.871 – 1.12 0.83 268 2937 exclusion phecode
520 Disorders of tooth development Digestive 1.01 0.962 – 1.06 0.736 1974 19794 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.13 0.854 – 1.5 0.385 51 513 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 1.01 0.971 – 1.06 0.548 2283 22893 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 0.991 0.954 – 1.03 0.629 2894 29405 exclusion phecode
521.1 Dental caries Digestive 0.988 0.951 – 1.03 0.532 2906 29490 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 0.975 0.928 – 1.02 0.321 1690 17178 exclusion phecode
522.5 Periapical abscess Digestive 0.992 0.933 – 1.05 0.788 1120 11356 exclusion phecode
523 Gingival and periodontal diseases Digestive 0.988 0.939 – 1.04 0.655 1611 16293 exclusion phecode
523.1 Gingivitis Digestive 0.985 0.809 – 1.2 0.878 106 1083 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.01 0.952 – 1.08 0.696 1120 11302 exclusion phecode
523.31 Acute periodontitis Digestive 0.972 0.896 – 1.05 0.49 642 6469 exclusion phecode
523.32 Chronic periodontitis Digestive 1.05 0.964 – 1.15 0.249 534 5409 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.952 0.848 – 1.07 0.402 324 3208 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.966 0.857 – 1.09 0.574 298 2960 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.02 0.976 – 1.06 0.419 2547 25843 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.79 0.608 – 1.03 0.0777 69 682 exclusion phecode
526 Diseases of the jaws Digestive 1.02 0.952 – 1.09 0.561 887 8958 exclusion phecode
526.1 Cysts of the jaws Digestive 1.02 0.912 – 1.15 0.683 323 3199 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.2 0.927 – 1.54 0.168 57 590 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.06 0.929 – 1.21 0.391 229 2306 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.05 0.918 – 1.21 0.463 222 2236 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 1.05 0.863 – 1.29 0.611 102 1058 exclusion phecode
526.9 Jaw disease NOS Digestive 0.918 0.799 – 1.05 0.227 224 2241 exclusion phecode
527 Diseases of the salivary glands Digestive 1.04 0.963 – 1.13 0.309 671 6715 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.13 0.901 – 1.42 0.29 82 806 exclusion phecode
527.2 Sialoadenitis Digestive 1.02 0.915 – 1.13 0.745 355 3534 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.09 0.846 – 1.41 0.496 60 595 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.03 0.846 – 1.24 0.798 113 1158 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.979 0.946 – 1.01 0.216 3689 37440 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.04 0.943 – 1.15 0.414 414 4512 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.06 0.953 – 1.19 0.271 345 3746 exclusion phecode
528.12 Oral aphthae Digestive 0.949 0.75 – 1.2 0.66 74 818 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.899 0.766 – 1.05 0.189 170 1738 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.887 0.738 – 1.07 0.204 119 1172 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.957 0.775 – 1.18 0.682 91 908 exclusion phecode
528.5 Diseases of lips Digestive 1.02 0.939 – 1.1 0.685 659 6572 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 0.914 0.81 – 1.03 0.146 300 2982 exclusion phecode
528.7 Sialolithiasis Digestive 1.01 0.901 – 1.14 0.841 306 3046 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.05 0.985 – 1.11 0.14 1184 11911 exclusion phecode
529.1 Glossitis Digestive 0.998 0.884 – 1.13 0.97 290 2890 exclusion phecode
530 Diseases of esophagus Digestive 1 0.989 – 1.01 0.985 32183 270320 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.999 0.987 – 1.01 0.892 30064 263723 exclusion phecode
530.11 GERD Digestive 0.994 0.98 – 1.01 0.418 21680 218171 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.01 0.979 – 1.04 0.626 5076 50706 exclusion phecode
530.14 Reflux esophagitis Digestive 0.99 0.97 – 1.01 0.336 10122 101202 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.988 0.939 – 1.04 0.635 1625 16282 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1 0.955 – 1.05 0.945 1807 18195 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1 0.922 – 1.09 0.959 606 6136 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.919 0.773 – 1.09 0.34 149 1470 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.969 0.867 – 1.08 0.581 333 3332 exclusion phecode
530.9 Heartburn Digestive 1 0.955 – 1.05 0.991 1997 20027 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.01 0.981 – 1.03 0.683 6880 68976 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.08 0.995 – 1.17 0.0643 614 6250 exclusion phecode
531.2 Gastric ulcer Digestive 1 0.97 – 1.04 0.911 3966 39549 exclusion phecode
531.3 Duodenal ulcer Digestive 0.993 0.956 – 1.03 0.709 2902 29284 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 0.979 0.885 – 1.08 0.677 415 4125 exclusion phecode
532 Dysphagia Digestive 0.987 0.961 – 1.01 0.333 6139 62009 exclusion phecode
535 Gastritis and duodenitis Digestive 1 0.99 – 1.02 0.667 27088 252842 exclusion phecode
535.1 Acute gastritis Digestive 0.964 0.907 – 1.02 0.23 1143 11420 exclusion phecode
535.2 Atrophic gastritis Digestive 1.03 0.921 – 1.14 0.646 358 3565 exclusion phecode
535.6 Duodenitis Digestive 0.997 0.973 – 1.02 0.774 7382 73936 exclusion phecode
535.8 Other specified gastritis Digestive 0.993 0.97 – 1.02 0.553 7789 77834 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.03 0.858 – 1.25 0.726 120 1150 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.946 0.828 – 1.08 0.418 245 2487 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.01 0.976 – 1.05 0.523 3259 32749 exclusion phecode
540 Appendiceal conditions Digestive 1.01 0.969 – 1.04 0.78 3010 30006 exclusion phecode
540.1 Appendicitis Digestive 0.988 0.951 – 1.03 0.53 2824 28138 exclusion phecode
540.11 Acute appendicitis Digestive 0.981 0.942 – 1.02 0.366 2537 25288 exclusion phecode
550 Abdominal hernia Digestive 0.994 0.984 – 1 0.235 44115 273698 exclusion phecode
550.1 Inguinal hernia Digestive 0.995 0.978 – 1.01 0.541 15711 122486 exclusion phecode
550.2 Diaphragmatic hernia Digestive 0.991 0.978 – 1 0.184 25417 230563 exclusion phecode
550.3 Femoral hernia Digestive 0.976 0.899 – 1.06 0.565 619 6195 exclusion phecode
550.4 Umbilical hernia Digestive 0.983 0.95 – 1.02 0.316 3647 36517 exclusion phecode
550.5 Ventral hernia Digestive 0.997 0.962 – 1.03 0.879 3292 33346 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 0.991 0.96 – 1.02 0.561 4281 43184 exclusion phecode
555.1 Regional enteritis Digestive 0.97 0.922 – 1.02 0.245 1674 16786 exclusion phecode
555.2 Ulcerative colitis Digestive 1 0.964 – 1.04 0.983 3058 30957 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.02 0.932 – 1.12 0.658 517 5237 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.04 0.98 – 1.11 0.185 1022 10222 exclusion phecode
556.1 Ulceration of intestine Digestive 1.04 0.957 – 1.12 0.388 648 6490 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.01 0.892 – 1.14 0.909 287 2894 exclusion phecode
557.1 Celiac disease Digestive 1.02 0.97 – 1.07 0.462 1775 17705 exclusion phecode
558 Noninfectious gastroenteritis Digestive 0.995 0.978 – 1.01 0.554 14741 149690 exclusion phecode
559 Ileostomy status Digestive 0.991 0.941 – 1.04 0.727 1590 16107 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.01 0.973 – 1.04 0.701 3755 38029 exclusion phecode
560.1 Paralytic ileus Digestive 1.06 0.969 – 1.16 0.199 512 5105 exclusion phecode
560.2 Impaction of intestine Digestive 0.987 0.869 – 1.12 0.847 256 2564 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.989 0.919 – 1.06 0.768 789 8048 exclusion phecode
560.4 Other intestinal obstruction Digestive 1 0.968 – 1.04 0.825 3191 32386 exclusion phecode
561 Symptoms involving digestive system Digestive 1.02 1 – 1.04 0.019 15026 151574 exclusion phecode
561.1 Diarrhea Digestive 1.03 0.933 – 1.14 0.56 435 4475 exclusion phecode
561.2 Flatulence Digestive 1.01 0.962 – 1.07 0.632 1593 16231 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 0.988 0.975 – 1 0.0677 25637 204914 exclusion phecode
562.1 Diverticulosis Digestive 0.988 0.975 – 1 0.0674 25598 204861 exclusion phecode
563 Constipation Digestive 0.982 0.962 – 1 0.0863 9758 99467 exclusion phecode
564 Functional digestive disorders Digestive 1 0.987 – 1.02 0.844 20802 203126 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.02 0.987 – 1.04 0.295 5226 52742 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 0.982 0.932 – 1.03 0.484 1566 15816 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 0.997 0.981 – 1.01 0.769 14683 147161 exclusion phecode
565 Anal and rectal conditions Digestive 0.98 0.963 – 0.997 0.0204 14315 143426 exclusion phecode
565.1 Anal and rectal polyp Digestive 0.967 0.943 – 0.99 0.00634 7136 71526 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 0.966 0.902 – 1.03 0.32 889 9069 exclusion phecode
568 Other disorders of peritoneum Digestive 0.998 0.962 – 1.04 0.927 3112 31324 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.999 0.961 – 1.04 0.942 2957 29747 exclusion phecode
569 Other disorders of intestine Digestive 1.02 0.99 – 1.06 0.176 3965 40472 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.929 0.778 – 1.11 0.419 122 1428 exclusion phecode
569.2 Gastrointestinal complications Digestive 0.932 0.847 – 1.02 0.145 466 4720 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.01 0.97 – 1.05 0.67 2842 28831 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.01 0.963 – 1.07 0.61 1623 16434 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.04 0.855 – 1.26 0.698 111 1097 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.09 0.963 – 1.24 0.169 239 2448 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.985 0.921 – 1.05 0.652 944 9617 exclusion phecode
571.81 Portal hypertension Digestive 0.979 0.895 – 1.07 0.644 515 5185 exclusion phecode
572 Ascites (non malignant) Digestive 0.998 0.945 – 1.05 0.936 1397 14929 exclusion phecode
573 Other disorders of liver Digestive 0.98 0.928 – 1.03 0.47 1419 14460 exclusion phecode
573.2 Liver replaced by transplant Digestive 0.912 0.733 – 1.14 0.414 92 945 exclusion phecode
573.3 Hepatomegaly Digestive 1.01 0.898 – 1.14 0.85 285 2899 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 0.994 0.926 – 1.07 0.86 857 8722 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 0.994 0.958 – 1.03 0.726 3286 33501 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.15 0.999 – 1.33 0.0515 201 2036 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1 0.986 – 1.02 0.773 14825 149444 exclusion phecode
574.1 Cholelithiasis Digestive 0.997 0.98 – 1.02 0.778 12864 129656 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.984 0.932 – 1.04 0.566 1436 14478 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.01 0.982 – 1.04 0.491 5171 51922 exclusion phecode
574.2 Calculus of bile duct Digestive 1 0.962 – 1.04 0.923 2497 25146 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.999 0.96 – 1.04 0.973 2614 26422 exclusion phecode
575 Other biliary tract disease Digestive 0.996 0.963 – 1.03 0.822 3651 37229 exclusion phecode
575.1 Cholangitis Digestive 0.943 0.858 – 1.04 0.22 481 4815 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.02 0.943 – 1.1 0.672 736 7518 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.993 0.899 – 1.1 0.886 429 4380 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.01 0.959 – 1.07 0.622 1321 13542 exclusion phecode
575.8 Other disorders of biliary tract Digestive 0.989 0.927 – 1.06 0.746 982 9921 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.992 0.887 – 1.11 0.886 321 3366 exclusion phecode
577 Diseases of pancreas Digestive 0.994 0.955 – 1.04 0.773 2551 25714 exclusion phecode
577.1 Acute pancreatitis Digestive 0.996 0.95 – 1.04 0.855 1906 19260 exclusion phecode
577.2 Chronic pancreatitis Digestive 0.985 0.9 – 1.08 0.751 509 5040 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.03 0.928 – 1.15 0.541 351 3517 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1 0.988 – 1.02 0.686 19860 199765 exclusion phecode
578.1 Hematemesis Digestive 1.03 0.978 – 1.07 0.301 1887 19075 exclusion phecode
578.2 Blood in stool Digestive 0.986 0.947 – 1.03 0.498 2526 25535 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.01 0.994 – 1.03 0.176 12581 126303 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.991 0.962 – 1.02 0.523 5093 51165 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.04 0.988 – 1.1 0.126 1465 14867 exclusion phecode
579.2 Splenomegaly Digestive 0.974 0.882 – 1.08 0.61 413 4163 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.976 0.926 – 1.03 0.349 1595 15990 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.01 0.959 – 1.07 0.658 1477 14898 exclusion phecode
580.1 Glomerulonephritis Genitourinary 0.984 0.922 – 1.05 0.626 1010 10204 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.943 0.746 – 1.19 0.62 73 716 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.91 0.757 – 1.09 0.313 131 1319 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.998 0.93 – 1.07 0.966 839 8476 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.09 0.995 – 1.2 0.0619 460 4588 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.979 0.857 – 1.12 0.755 237 2401 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.976 0.855 – 1.11 0.724 244 2471 exclusion phecode
585 Renal failure Genitourinary 0.992 0.968 – 1.02 0.554 6669 67938 exclusion phecode
585.1 Acute renal failure Genitourinary 1.02 0.984 – 1.05 0.336 4323 44204 exclusion phecode
585.2 Renal failure NOS Genitourinary 0.96 0.909 – 1.01 0.143 1409 14280 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.976 0.936 – 1.02 0.237 2544 25771 exclusion phecode
585.31 Renal dialysis Genitourinary 0.993 0.903 – 1.09 0.881 477 4858 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.03 0.991 – 1.07 0.141 3238 32690 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.863 0.745 – 0.998 0.0474 201 2030 exclusion phecode
586.11 Small kidney Genitourinary 0.885 0.756 – 1.03 0.126 174 1748 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.04 0.977 – 1.1 0.229 1220 12241 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.978 0.782 – 1.22 0.842 78 787 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.993 0.927 – 1.06 0.844 874 8878 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.07 0.963 – 1.2 0.197 350 3604 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.1 0.904 – 1.34 0.341 98 954 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.06 0.88 – 1.28 0.537 109 1119 exclusion phecode
590 Pyelonephritis Genitourinary 1.04 0.98 – 1.1 0.206 1260 12753 exclusion phecode
591 Urinary tract infection Genitourinary 1 0.985 – 1.02 0.675 11735 119390 exclusion phecode
592 Cystitis and urethritis Genitourinary 0.98 0.943 – 1.02 0.314 2840 28450 exclusion phecode
592.1 Cystitis Genitourinary 0.981 0.943 – 1.02 0.333 2780 27825 exclusion phecode
592.11 Acute cystitis Genitourinary 0.897 0.751 – 1.07 0.231 137 1325 exclusion phecode
592.12 Chronic cystitis Genitourinary 1.01 0.943 – 1.09 0.75 847 8511 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.07 0.943 – 1.23 0.279 237 2344 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.04 0.886 – 1.22 0.634 162 1619 exclusion phecode
593 Hematuria Genitourinary 0.992 0.976 – 1.01 0.347 15600 155884 exclusion phecode
594 Urinary calculus Genitourinary 0.972 0.947 – 0.998 0.0355 6234 62613 exclusion phecode
594.1 Calculus of kidney Genitourinary 0.968 0.933 – 1 0.0837 3097 31123 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 0.972 0.903 – 1.05 0.455 764 7686 exclusion phecode
594.3 Calculus of ureter Genitourinary 0.986 0.945 – 1.03 0.501 2367 23720 exclusion phecode
594.8 Renal colic Genitourinary 0.995 0.95 – 1.04 0.827 2008 20149 exclusion phecode
595 Hydronephrosis Genitourinary 1.02 0.975 – 1.07 0.364 1850 18945 exclusion phecode
596 Other disorders of bladder Genitourinary 0.976 0.956 – 0.997 0.0257 9500 95543 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 0.978 0.933 – 1.02 0.347 1957 19625 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 0.963 0.915 – 1.01 0.154 1601 16007 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.995 0.962 – 1.03 0.764 3782 38016 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.994 0.959 – 1.03 0.755 3216 32287 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.1 0.881 – 1.37 0.397 75 749 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 0.991 0.957 – 1.03 0.618 3437 34518 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.03 0.917 – 1.17 0.579 288 2945 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.99 0.974 – 1.01 0.186 17688 177834 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.937 0.798 – 1.1 0.426 161 1645 exclusion phecode
599.2 Retention of urine Genitourinary 0.981 0.957 – 1.01 0.145 6564 66108 exclusion phecode
599.3 Dysuria Genitourinary 0.966 0.909 – 1.03 0.257 1148 11610 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.989 0.967 – 1.01 0.336 8270 82937 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.01 0.973 – 1.04 0.726 3904 39055 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1 0.814 – 1.23 0.986 99 1020 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.17 0.888 – 1.54 0.264 58 602 exclusion phecode
599.9 Other abnormality of urination Genitourinary 0.943 0.899 – 0.99 0.0173 1873 18791 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.968 0.949 – 0.987 0.00119 11082 87821 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 1.01 0.968 – 1.06 0.579 2080 20803 exclusion phecode
601.1 Prostatitis Genitourinary 0.996 0.945 – 1.05 0.875 1562 15634 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.99 0.866 – 1.13 0.888 234 2357 exclusion phecode
601.12 Chronic prostatitis Genitourinary 0.945 0.882 – 1.01 0.104 910 9081 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.857 0.656 – 1.12 0.258 59 588 exclusion phecode
601.4 Balanoposthitis Genitourinary 1.03 0.907 – 1.16 0.69 287 2862 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.15 1.02 – 1.29 0.0203 303 3017 exclusion phecode
602 Other disorders of prostate Genitourinary 0.983 0.929 – 1.04 0.545 1338 13394 exclusion phecode
603 Other disorders of testis Genitourinary 0.986 0.943 – 1.03 0.519 2146 21499 exclusion phecode
603.1 Hydrocele Genitourinary 1.01 0.958 – 1.07 0.631 1337 13393 exclusion phecode
604 Disorders of penis Genitourinary 1.02 0.984 – 1.06 0.281 3276 32764 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.03 0.989 – 1.07 0.159 2718 27161 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 1.03 0.91 – 1.16 0.666 278 2799 exclusion phecode
608 Other disorders of male genital organs Genitourinary 0.986 0.949 – 1.02 0.469 2820 28217 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1 0.871 – 1.16 0.955 213 2136 exclusion phecode
609.1 Infertility, male Genitourinary 1.18 0.916 – 1.51 0.203 63 638 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.938 0.798 – 1.1 0.441 168 1696 exclusion phecode
610 Benign mammary dysplasias Genitourinary 1.03 0.984 – 1.08 0.201 1883 23623 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.993 0.92 – 1.07 0.847 720 8745 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1.06 0.911 – 1.23 0.45 179 2892 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 1.06 0.921 – 1.23 0.4 184 2871 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 1.06 1 – 1.13 0.0492 1131 13188 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.02 0.94 – 1.12 0.587 570 6579 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.09 1.03 – 1.16 0.00534 1094 14957 exclusion phecode
611.3 Lump or mass in breast Genitourinary 1.09 1.02 – 1.15 0.00914 1062 14482 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.2 1.11 – 1.29 1.74e-06 747 8533 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.2 1.12 – 1.3 1.47e-06 715 8164 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 1.13 0.885 – 1.44 0.33 63 688 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 1.08 1.01 – 1.14 0.0173 1123 15621 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.03 0.938 – 1.13 0.557 489 6849 exclusion phecode
613.5 Mastodynia Genitourinary 1.07 0.811 – 1.41 0.639 52 735 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 1.13 1.04 – 1.23 0.00524 580 6605 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1.15 0.995 – 1.34 0.0584 171 3110 exclusion phecode
613.9 Breast disorder NOS Genitourinary 1.07 0.904 – 1.26 0.437 139 1937 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.01 0.977 – 1.03 0.712 5351 54199 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.02 0.982 – 1.07 0.265 2404 24133 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1 0.929 – 1.08 0.986 779 7899 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.21 0.914 – 1.6 0.183 55 571 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.05 0.943 – 1.16 0.392 397 4011 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.934 0.833 – 1.05 0.239 328 3345 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.07 0.942 – 1.21 0.3 250 2642 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.978 0.938 – 1.02 0.304 2427 24640 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.981 0.925 – 1.04 0.528 1229 12479 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.01 0.91 – 1.12 0.862 399 4019 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.964 0.892 – 1.04 0.356 707 7170 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.02 0.898 – 1.16 0.748 250 2579 exclusion phecode
615 Endometriosis Genitourinary 0.999 0.966 – 1.03 0.933 3799 38316 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 0.95 0.841 – 1.07 0.417 277 2873 exclusion phecode
618 Genital prolapse Genitourinary 0.981 0.961 – 1 0.0509 10983 109367 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.979 0.955 – 1 0.0914 6944 69176 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.964 0.936 – 0.992 0.0127 5058 50422 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.95 0.865 – 1.04 0.275 493 4747 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.06 0.978 – 1.15 0.153 635 6336 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1.02 0.993 – 1.04 0.169 8075 82518 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.997 0.921 – 1.08 0.932 670 6936 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 0.992 0.955 – 1.03 0.665 3022 31318 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.02 0.977 – 1.06 0.407 2667 27073 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.05 0.997 – 1.1 0.0673 1639 16655 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.04 0.983 – 1.1 0.17 1272 12763 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 0.964 0.758 – 1.23 0.766 65 679 exclusion phecode
621 Endometrial hyperplasia Genitourinary 1.04 0.97 – 1.1 0.293 979 10644 exclusion phecode
622 Polyp of female genital organs Genitourinary 1.02 0.998 – 1.04 0.0759 9371 98870 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 1.01 0.985 – 1.03 0.452 6936 74136 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 1.03 0.995 – 1.07 0.089 3160 32418 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.01 0.947 – 1.07 0.847 1172 12060 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.914 0.846 – 0.987 0.0214 730 7402 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.879 0.765 – 1.01 0.0685 220 2208 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 0.932 0.84 – 1.03 0.186 397 4080 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.975 0.948 – 1 0.0747 5521 55090 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.01 0.97 – 1.05 0.677 2725 27372 exclusion phecode
625.1 Dyspareunia Genitourinary 1.01 0.953 – 1.08 0.687 1130 11313 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.01 0.989 – 1.02 0.475 15278 109469 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.01 0.987 – 1.02 0.554 13378 104677 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 1.06 0.868 – 1.3 0.553 100 1059 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1 0.982 – 1.03 0.755 9249 87559 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 1.02 0.973 – 1.07 0.387 1845 18826 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 1.01 0.974 – 1.04 0.646 3612 36268 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.983 0.935 – 1.03 0.5 1709 17054 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.997 0.843 – 1.18 0.973 154 1530 exclusion phecode
626.8 Infertility, female Genitourinary 1 0.946 – 1.06 0.974 1303 13128 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.01 0.993 – 1.04 0.19 9194 97523 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 1.01 0.99 – 1.04 0.267 7940 84785 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.931 0.792 – 1.09 0.382 166 1711 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.02 0.959 – 1.09 0.493 1000 10418 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 0.974 0.863 – 1.1 0.675 297 2931 exclusion phecode
628 Ovarian cyst Genitourinary 0.985 0.954 – 1.02 0.325 4412 45211 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.02 0.99 – 1.05 0.203 5032 35198 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.99 0.93 – 1.05 0.74 1092 10946 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.06 0.948 – 1.19 0.302 318 3184 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.07 1.02 – 1.12 0.00873 1912 16882 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.05 0.982 – 1.13 0.147 841 8372 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.06 1 – 1.13 0.0403 1228 11979 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.03 0.99 – 1.08 0.13 2272 19393 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 1.02 0.939 – 1.11 0.604 597 5972 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.07 1.01 – 1.14 0.034 1038 10442 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 1.3 1.02 – 1.66 0.0329 69 676 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.05 0.991 – 1.12 0.0924 1087 10778 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.02 0.909 – 1.15 0.696 301 2970 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.02 0.893 – 1.17 0.734 212 2090 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.07 0.912 – 1.25 0.407 152 1484 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.03 0.973 – 1.09 0.298 1219 12107 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.02 0.977 – 1.07 0.362 2166 20249 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.41 1.1 – 1.82 0.00719 65 650 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.98 0.865 – 1.11 0.75 271 2665 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.21 0.996 – 1.48 0.0548 111 1104 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.04 0.893 – 1.2 0.646 185 1870 exclusion phecode
650 Normal delivery Pregnancy Complications 1.02 0.969 – 1.07 0.516 1870 18412 exclusion phecode
651 Multiple gestation Pregnancy Complications 1.01 0.906 – 1.14 0.807 339 3349 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1.01 0.956 – 1.06 0.836 1670 16087 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.01 0.955 – 1.07 0.737 1361 13271 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.36 1.07 – 1.72 0.0108 70 723 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.01 0.979 – 1.05 0.477 4175 28574 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.07 0.884 – 1.3 0.475 109 1051 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 1.05 1.01 – 1.1 0.026 2195 17883 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 1 0.918 – 1.1 0.918 521 5167 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 1.04 1.01 – 1.07 0.0157 5179 28548 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.04 1 – 1.09 0.0473 2469 20539 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.987 0.836 – 1.17 0.878 157 1577 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1 0.88 – 1.14 0.997 255 2541 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.05 0.814 – 1.36 0.691 60 612 exclusion phecode
679 Complications of in utero procedures Dermatologic 1.08 0.834 – 1.41 0.551 51 513 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 0.972 0.948 – 0.996 0.0252 6754 70395 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.03 0.941 – 1.12 0.533 535 5478 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.968 0.882 – 1.06 0.489 497 5024 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.968 0.941 – 0.996 0.0238 5221 53756 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.969 0.942 – 0.997 0.028 5226 53817 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.966 0.939 – 0.994 0.0162 5186 53387 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.07 0.977 – 1.18 0.143 491 5781 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.01 0.949 – 1.07 0.84 1264 13069 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 0.975 0.933 – 1.02 0.252 2210 22339 exclusion phecode
686.3 Pilonidal cyst Dermatologic 0.993 0.912 – 1.08 0.865 572 5762 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 0.929 0.832 – 1.04 0.19 343 3500 exclusion phecode
687 Symptoms affecting skin Dermatologic 1.09 0.999 – 1.19 0.0538 518 5299 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.01 0.964 – 1.06 0.694 2017 20814 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.13 1 – 1.28 0.0418 265 2736 exclusion phecode
687.3 Changes in skin texture Dermatologic 1.03 0.849 – 1.25 0.757 104 1035 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.04 0.997 – 1.08 0.0742 2780 27926 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.03 0.998 – 1.06 0.0648 5459 55556 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.907 0.714 – 1.15 0.427 70 702 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.867 0.657 – 1.14 0.313 53 527 exclusion phecode
691 Congenital anomalies of skin Dermatologic 1.19 0.977 – 1.44 0.084 112 1155 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 1.04 0.971 – 1.11 0.269 933 9479 exclusion phecode
694.1 Vitiligo Dermatologic 1.1 0.862 – 1.42 0.431 58 574 exclusion phecode
694.2 Other dyschromia Dermatologic 1.02 0.947 – 1.1 0.58 740 7517 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 0.979 0.808 – 1.18 0.825 110 1137 exclusion phecode
695 Erythematous conditions Dermatologic 0.997 0.955 – 1.04 0.9 2247 22923 exclusion phecode
695.1 Toxic erythema Dermatologic 1.02 0.839 – 1.25 0.822 105 1043 exclusion phecode
695.2 Bullous dermatoses Dermatologic 0.96 0.804 – 1.15 0.649 129 1318 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 1 0.77 – 1.3 0.986 53 552 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.938 0.743 – 1.18 0.59 69 697 exclusion phecode
695.3 Rosacea Dermatologic 1.02 0.905 – 1.14 0.774 300 3000 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1 0.905 – 1.11 0.949 398 3902 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.08 0.902 – 1.3 0.394 125 1238 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 0.967 0.864 – 1.08 0.567 329 3224 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 0.982 0.909 – 1.06 0.633 731 7461 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 0.942 0.82 – 1.08 0.399 219 2282 exclusion phecode
695.81 Erythema nodosum Dermatologic 1.04 0.815 – 1.32 0.759 71 733 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.03 0.931 – 1.13 0.593 427 4540 exclusion phecode
696 Psoriasis and related disorders Dermatologic 1.01 0.966 – 1.06 0.667 2168 21893 exclusion phecode
696.4 Psoriasis Dermatologic 1.01 0.965 – 1.06 0.683 2114 21361 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 1.04 0.984 – 1.09 0.177 1604 16325 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.94 0.868 – 1.02 0.122 692 6836 exclusion phecode
697 Sarcoidosis Dermatologic 1.02 0.932 – 1.12 0.654 510 5188 exclusion phecode
698 Pruritus and related conditions Dermatologic 0.987 0.916 – 1.06 0.728 752 7527 exclusion phecode
700 Corns and callosities Dermatologic 0.974 0.864 – 1.1 0.67 278 2763 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.02 0.987 – 1.05 0.247 4116 45006 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 1.05 0.83 – 1.33 0.675 83 845 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.03 0.986 – 1.08 0.17 1969 22605 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 1.02 0.795 – 1.32 0.859 59 579 exclusion phecode
701.4 Keloid scar Dermatologic 1.13 0.973 – 1.31 0.11 182 2073 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1.01 0.917 – 1.12 0.792 417 4394 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 0.883 0.714 – 1.09 0.251 97 975 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.991 0.963 – 1.02 0.519 5200 52601 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.998 0.958 – 1.04 0.921 2490 24879 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.976 0.94 – 1.01 0.22 2903 29611 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.02 0.913 – 1.14 0.714 338 3415 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.967 0.904 – 1.03 0.328 935 9400 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.99 0.961 – 1.02 0.482 5073 51172 exclusion phecode
704.1 Alopecia Dermatologic 1.05 0.874 – 1.26 0.615 118 1198 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.789 0.624 – 0.999 0.0486 74 734 exclusion phecode
705 Disorders of sweat glands Dermatologic 1.05 0.917 – 1.21 0.475 224 2215 exclusion phecode
705.3 Hidradenitis Dermatologic 1.08 0.932 – 1.26 0.303 182 1804 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.02 0.933 – 1.11 0.698 583 5785 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1 0.982 – 1.03 0.678 8013 80635 exclusion phecode
706.1 Acne Dermatologic 1.17 0.917 – 1.5 0.203 75 757 exclusion phecode
706.2 Sebaceous cyst Dermatologic 0.999 0.977 – 1.02 0.944 8466 85173 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.01 0.964 – 1.06 0.673 1870 19141 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.03 0.957 – 1.1 0.479 861 8851 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 1.03 0.99 – 1.06 0.163 3247 32831 exclusion phecode
709.2 Sicca syndrome Dermatologic 0.939 0.855 – 1.03 0.19 473 4776 exclusion phecode
709.3 Systemic sclerosis Dermatologic 0.948 0.807 – 1.11 0.515 165 1665 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.24 0.955 – 1.6 0.107 59 618 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.03 0.989 – 1.07 0.154 2577 26058 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.06 0.969 – 1.15 0.214 581 5890 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.04 0.956 – 1.14 0.336 537 5438 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.12 0.96 – 1.3 0.152 187 1899 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.971 0.874 – 1.08 0.582 386 3903 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 1 0.905 – 1.11 0.98 414 4110 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 0.957 0.854 – 1.07 0.445 322 3215 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 0.978 0.778 – 1.23 0.846 78 781 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.07 0.898 – 1.27 0.463 145 1458 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.11 0.859 – 1.44 0.417 63 662 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.99 0.96 – 1.02 0.508 4590 46275 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.986 0.955 – 1.02 0.377 4161 41863 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.964 0.915 – 1.02 0.164 1573 16048 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.04 0.855 – 1.26 0.699 110 1078 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.943 0.866 – 1.03 0.17 600 6049 exclusion phecode
716 Other arthropathies Musculoskeletal 0.982 0.971 – 0.993 0.00153 35647 256935 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.997 0.961 – 1.03 0.852 3306 33554 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.975 0.958 – 0.991 0.00307 14915 150303 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 0.982 0.971 – 0.993 0.00138 34200 253946 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.05 0.984 – 1.11 0.145 1094 10903 exclusion phecode
720 Spinal stenosis Musculoskeletal 1 0.97 – 1.04 0.823 3562 35801 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1 0.976 – 1.02 0.977 7431 75200 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1 0.972 – 1.03 0.91 4798 48447 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.07 0.917 – 1.24 0.399 178 1852 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 0.895 0.799 – 1 0.0549 331 3386 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 0.997 0.975 – 1.02 0.787 8658 86963 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.04 0.951 – 1.14 0.373 497 4983 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.986 0.948 – 1.03 0.492 2718 27318 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 0.871 0.668 – 1.14 0.31 63 655 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.99 0.959 – 1.02 0.519 4254 42786 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.06 0.966 – 1.16 0.223 497 5043 exclusion phecode
723.1 Torticollis Musculoskeletal 1.17 0.957 – 1.42 0.127 102 1025 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 0.991 0.946 – 1.04 0.701 1963 19868 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 0.949 0.853 – 1.06 0.337 383 3844 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.953 0.857 – 1.06 0.375 386 3876 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 0.838 0.639 – 1.1 0.2 58 600 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1 0.954 – 1.06 0.862 1549 15689 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.01 0.992 – 1.03 0.282 14198 141816 exclusion phecode
726.1 Enthesopathy Musculoskeletal 1 0.983 – 1.03 0.72 9269 92496 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.99 0.883 – 1.11 0.863 318 3214 exclusion phecode
726.3 Bursitis Musculoskeletal 0.995 0.927 – 1.07 0.888 844 8454 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.01 0.981 – 1.03 0.652 7051 70688 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.02 0.983 – 1.06 0.27 2643 26427 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 1.19 0.969 – 1.45 0.0974 102 1006 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.991 0.955 – 1.03 0.644 2979 29838 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 1.03 0.941 – 1.12 0.557 560 5641 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.948 0.847 – 1.06 0.353 336 3416 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.04 0.871 – 1.24 0.678 138 1384 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.03 0.993 – 1.06 0.114 3602 36133 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.07 0.967 – 1.18 0.197 402 4004 exclusion phecode
728.7 Fasciitis Musculoskeletal 1.03 0.991 – 1.06 0.146 3724 37323 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.03 0.99 – 1.06 0.166 3407 34185 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 0.993 0.966 – 1.02 0.612 5696 58101 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.03 0.959 – 1.1 0.459 945 9546 exclusion phecode
729.3 Panniculitis Musculoskeletal 1.03 0.837 – 1.27 0.766 97 982 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.03 0.909 – 1.17 0.635 257 2652 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.04 0.915 – 1.18 0.541 243 2511 exclusion phecode
732 Osteochondropathies Musculoskeletal 1.03 0.933 – 1.13 0.595 453 4545 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.1 0.954 – 1.27 0.189 198 2014 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 1 0.761 – 1.31 0.997 56 564 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.977 0.927 – 1.03 0.379 1553 16986 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.03 0.891 – 1.18 0.713 211 2962 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.988 0.903 – 1.08 0.797 507 5206 exclusion phecode
733.6 Costochondritis Musculoskeletal 0.961 0.799 – 1.16 0.675 124 1220 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.961 0.904 – 1.02 0.193 1181 11924 exclusion phecode
733.9 Chondromalacia Musculoskeletal 0.922 0.758 – 1.12 0.415 116 1173 exclusion phecode
735 Acquired foot deformities Musculoskeletal 0.988 0.967 – 1.01 0.284 9051 90789 exclusion phecode
735.1 Flat foot Musculoskeletal 0.972 0.832 – 1.14 0.72 175 1848 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 0.979 0.95 – 1.01 0.169 4784 47984 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.942 0.897 – 0.988 0.0151 1825 18237 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 1.04 0.982 – 1.09 0.204 1461 14783 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.983 0.958 – 1.01 0.207 6255 62528 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 0.997 0.946 – 1.05 0.899 1559 15691 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.04 0.906 – 1.19 0.596 243 2397 exclusion phecode
737 Curvature of spine Musculoskeletal 1.01 0.949 – 1.08 0.739 1059 10736 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.996 0.933 – 1.06 0.892 994 10087 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.987 0.941 – 1.04 0.608 1821 18241 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.967 0.916 – 1.02 0.229 1441 14441 exclusion phecode
739 Contracture of joint Musculoskeletal 1.03 0.941 – 1.14 0.492 471 4698 exclusion phecode
740 Osteoarthrosis Musculoskeletal 0.99 0.977 – 1 0.126 26358 223479 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.991 0.976 – 1.01 0.282 16646 163111 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.995 0.974 – 1.02 0.686 8604 86448 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.07 0.961 – 1.2 0.204 334 3350 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.01 0.929 – 1.1 0.769 569 5700 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.996 0.977 – 1.02 0.694 11561 117767 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.985 0.951 – 1.02 0.406 3437 34498 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.987 0.802 – 1.21 0.901 98 982 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 0.995 0.916 – 1.08 0.911 595 5934 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 1.15 0.973 – 1.35 0.103 145 1486 exclusion phecode
741.4 Joint effusions Musculoskeletal 0.959 0.907 – 1.01 0.145 1363 13791 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 0.845 0.693 – 1.03 0.0964 104 1065 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 1.26 0.944 – 1.67 0.118 51 515 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.994 0.956 – 1.03 0.773 2774 27658 exclusion phecode
742.1 Loose body in joint Musculoskeletal 1.03 0.916 – 1.15 0.647 322 3262 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1 0.81 – 1.24 0.99 94 941 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 0.879 0.799 – 0.966 0.00772 481 4844 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 1.01 0.963 – 1.06 0.713 1956 19390 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.01 0.984 – 1.03 0.5 6905 71858 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.01 0.981 – 1.04 0.577 5809 60678 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.02 0.991 – 1.05 0.184 5003 52449 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 0.965 0.879 – 1.06 0.452 498 5118 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 0.93 0.846 – 1.02 0.136 475 4972 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.08 1 – 1.16 0.0396 772 7831 exclusion phecode
745 Pain in joint Musculoskeletal 1 0.977 – 1.02 0.954 7627 76938 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.951 0.914 – 0.99 0.0141 2702 27276 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.954 0.916 – 0.994 0.0257 2534 25608 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.923 0.845 – 1.01 0.0769 563 5643 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.901 0.784 – 1.04 0.144 225 2307 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.957 0.911 – 1 0.0769 1748 17745 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.897 0.757 – 1.06 0.214 160 1618 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.992 0.883 – 1.11 0.887 297 2949 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.959 0.885 – 1.04 0.306 652 6670 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.08 0.963 – 1.21 0.191 315 3175 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.11 0.958 – 1.29 0.164 187 1861 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.874 0.781 – 0.978 0.0185 335 3462 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.841 0.731 – 0.968 0.0158 212 2193 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.886 0.727 – 1.08 0.231 109 1130 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.997 0.945 – 1.05 0.904 1468 14841 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.01 0.937 – 1.1 0.74 667 6695 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.03 0.933 – 1.13 0.583 429 4309 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.978 0.85 – 1.13 0.759 220 2214 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.996 0.926 – 1.07 0.906 803 8171 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.982 0.886 – 1.09 0.721 407 4153 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.02 0.904 – 1.14 0.801 320 3228 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.1 0.977 – 1.23 0.119 316 3195 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.07 0.94 – 1.22 0.303 245 2472 exclusion phecode
752.11 Spina bifida Congenital Anomalies 1.09 0.94 – 1.25 0.264 203 2041 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.05 0.825 – 1.33 0.71 73 760 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.946 0.789 – 1.13 0.546 123 1218 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1 0.795 – 1.27 0.967 73 734 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.969 0.783 – 1.2 0.775 99 1051 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.964 0.87 – 1.07 0.483 413 4090 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.98 0.845 – 1.14 0.786 204 1991 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.915 0.777 – 1.08 0.287 156 1539 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.905 0.739 – 1.11 0.331 104 1012 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.918 0.841 – 1 0.057 563 5649 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.781 0.619 – 0.984 0.0357 79 778 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.918 0.829 – 1.02 0.101 419 4195 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.01 0.854 – 1.2 0.896 139 1649 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.15 0.877 – 1.5 0.318 51 801 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1 0.874 – 1.15 0.987 206 2087 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.906 0.735 – 1.12 0.352 94 920 exclusion phecode
760 Back pain Symptoms 1.01 0.993 – 1.03 0.219 10641 107485 exclusion phecode
761 Cervicalgia Symptoms 0.982 0.935 – 1.03 0.487 1714 17304 exclusion phecode
764 Sciatica Symptoms 1.01 0.968 – 1.05 0.643 2278 22854 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.01 0.948 – 1.07 0.788 1116 11313 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.03 0.95 – 1.12 0.466 601 6105 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.959 0.893 – 1.03 0.257 823 8388 exclusion phecode
771.1 Swelling of limb Symptoms 0.992 0.962 – 1.02 0.615 4374 44747 exclusion phecode
772 Symptoms of the muscles Symptoms 1.03 0.952 – 1.12 0.438 632 6387 exclusion phecode
773 Pain in limb Symptoms 0.994 0.968 – 1.02 0.682 5930 59940 exclusion phecode
780 Hypothermia/Chills Symptoms 1.16 0.985 – 1.37 0.0751 158 1659 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.978 0.932 – 1.03 0.373 1785 18158 exclusion phecode
782.3 Edema Symptoms 1.01 0.963 – 1.07 0.583 1544 15897 exclusion phecode
782.6 Pallor and flushing Symptoms 0.949 0.806 – 1.12 0.524 162 1697 exclusion phecode
783 Fever of unknown origin Symptoms 0.998 0.964 – 1.03 0.909 3475 37922 exclusion phecode
785 Abdominal pain Symptoms 1.01 0.996 – 1.02 0.208 38482 292262 exclusion phecode
788 Syncope and collapse Symptoms 0.998 0.977 – 1.02 0.882 8729 88191 exclusion phecode
789 Nausea and vomiting Symptoms 0.994 0.975 – 1.01 0.559 10790 111496 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.04 0.873 – 1.23 0.677 143 1445 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 0.949 0.753 – 1.2 0.658 77 802 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 0.968 0.943 – 0.993 0.0143 6184 62714 exclusion phecode
791 Gangrene Symptoms 0.965 0.882 – 1.06 0.435 520 5379 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.995 0.805 – 1.23 0.965 95 966 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.998 0.829 – 1.2 0.979 114 1300 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.01 0.927 – 1.11 0.775 516 5456 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.908 0.755 – 1.09 0.303 117 1173 exclusion phecode
797 Shock Symptoms 1.05 0.896 – 1.24 0.533 152 1531 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.13 0.925 – 1.37 0.234 102 1005 exclusion phecode
798 Malaise and fatigue Symptoms 1.02 0.988 – 1.06 0.197 3181 32896 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1.08 0.993 – 1.18 0.07 561 5663 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.01 0.987 – 1.04 0.338 6720 67642 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.991 0.944 – 1.04 0.724 1720 17359 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.886 0.757 – 1.04 0.131 162 1630 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.01 0.961 – 1.05 0.815 2081 20930 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 1.07 0.993 – 1.15 0.0745 745 7459 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.02 0.972 – 1.06 0.471 2114 21254 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.02 0.969 – 1.07 0.498 1757 17698 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.02 0.946 – 1.11 0.571 691 6939 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 1.02 0.997 – 1.04 0.094 7885 79487 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1.02 0.969 – 1.07 0.458 1610 16201 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.01 0.978 – 1.04 0.617 4932 49662 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.05 0.994 – 1.1 0.0814 1473 14930 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.988 0.953 – 1.02 0.52 3234 32439 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.02 0.968 – 1.08 0.396 1292 13198 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.04 0.964 – 1.12 0.315 760 7589 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.01 0.952 – 1.07 0.771 1263 12641 exclusion phecode
817 Concussion Injuries & Poisonings 0.947 0.828 – 1.08 0.429 235 2367 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.963 0.878 – 1.06 0.428 506 5089 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.03 0.992 – 1.07 0.123 2897 29043 exclusion phecode
823 Torus fracture Injuries & Poisonings 0.995 0.946 – 1.05 0.852 1615 16204 exclusion phecode
830 Dislocation Injuries & Poisonings 1 0.96 – 1.05 0.83 2040 20395 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.998 0.982 – 1.02 0.841 14824 148273 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 1.06 0.967 – 1.16 0.219 505 5132 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.977 0.887 – 1.08 0.647 461 4600 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.985 0.956 – 1.02 0.331 4604 50976 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.935 0.784 – 1.11 0.451 130 1516 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 0.945 0.861 – 1.04 0.239 473 4889 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.99 0.942 – 1.04 0.687 1738 17885 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.967 0.912 – 1.03 0.276 1200 12086 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.966 0.931 – 1 0.0753 3028 30471 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 0.985 0.948 – 1.02 0.419 2914 31400 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 0.948 0.731 – 1.23 0.685 66 661 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.03 0.996 – 1.07 0.0835 3399 34307 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.07 0.947 – 1.22 0.27 258 2655 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1 0.863 – 1.16 0.978 191 1911 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.04 0.999 – 1.08 0.0568 2825 28437 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.06 0.918 – 1.22 0.443 213 2163 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 1.01 0.784 – 1.3 0.94 68 666 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 0.995 0.963 – 1.03 0.748 3985 39843 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.06 0.804 – 1.39 0.688 53 526 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.09 0.877 – 1.35 0.442 88 877 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.995 0.853 – 1.16 0.953 170 1731 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1 0.912 – 1.1 0.941 472 4688 exclusion phecode
873 Broken tooth Injuries & Poisonings 0.966 0.841 – 1.11 0.624 222 2211 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 0.992 0.848 – 1.16 0.922 167 1689 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 0.951 0.806 – 1.12 0.555 149 1536 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 0.993 0.937 – 1.05 0.8 1282 12839 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.02 0.984 – 1.05 0.326 4096 41482 exclusion phecode
916 Contusion Injuries & Poisonings 0.983 0.931 – 1.04 0.551 1401 14081 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 1.03 0.88 – 1.2 0.73 171 1728 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.02 0.915 – 1.13 0.745 369 3772 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.986 0.864 – 1.13 0.837 246 2457 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.959 0.915 – 1 0.0758 1984 20324 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.989 0.86 – 1.14 0.88 206 2167 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.06 0.863 – 1.31 0.574 92 1006 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.02 0.933 – 1.12 0.653 520 5321 exclusion phecode
947 Urticaria Injuries & Poisonings 0.927 0.832 – 1.03 0.169 354 3563 exclusion phecode
949 Allergies, other Injuries & Poisonings 0.887 0.798 – 0.986 0.0257 384 3852 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.03 0.927 – 1.13 0.625 409 4114 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.03 0.911 – 1.17 0.61 259 2585 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.998 0.909 – 1.09 0.965 475 4825 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.11 0.852 – 1.44 0.443 54 543 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.18 0.936 – 1.49 0.159 73 731 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.01 0.992 – 1.02 0.357 16929 174200 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.01 0.989 – 1.02 0.482 14859 152759 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 0.906 0.815 – 1.01 0.0662 389 4013 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.05 0.974 – 1.13 0.214 781 8254 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.05 0.939 – 1.17 0.406 340 3571 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.04 0.932 – 1.16 0.471 335 3501 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.04 0.903 – 1.2 0.575 204 2160 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.946 0.835 – 1.07 0.386 267 2773 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.95 0.837 – 1.08 0.426 260 2715 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1 0.975 – 1.03 0.912 5720 58634 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.01 0.945 – 1.07 0.827 1031 10931 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.94 0.855 – 1.03 0.198 458 4644 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.16 1.04 – 1.28 0.00633 394 3949 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.98 0.895 – 1.07 0.664 497 4957 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.1 1.01 – 1.19 0.0373 541 5637 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.02 0.971 – 1.07 0.466 1884 18988 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.05 0.903 – 1.22 0.543 186 1863 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.06 0.937 – 1.19 0.365 265 2647 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.08 0.87 – 1.35 0.477 82 836 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 0.882 0.719 – 1.08 0.229 106 1053 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.03 0.833 – 1.28 0.782 98 996 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.18 0.919 – 1.52 0.193 61 612 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.08 0.819 – 1.42 0.595 53 561 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.996 0.868 – 1.14 0.953 215 2258 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.02 0.941 – 1.1 0.66 668 6752 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.97 0.839 – 1.12 0.676 195 1937 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 0.976 0.751 – 1.27 0.854 61 606 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 0.986 0.808 – 1.2 0.887 104 1030 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.955 0.786 – 1.16 0.645 106 1086 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.985 0.788 – 1.23 0.892 85 867 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.02 0.972 – 1.06 0.472 2105 30165 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.01 0.972 – 1.05 0.573 2553 29336 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.01 0.972 – 1.05 0.573 2553 29336 exclusion phecode
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