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Scores Breast cancer [female] UK Biobank (UKB) PheWAS analysis

Breast cancer [female] — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID prsweb-phecode174-1-icogs-er-positive-brca-prs-cs-ukb-20200608Legacy PRS-CSPRS-CSMichailidou K et al. 2018

Evaluation cohort: UK Biobank (UKB).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

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144 rows visible 16 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.01 0.985 – 1.03 0.571 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.01 0.974 – 1.05 0.502 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.13 1.04 – 1.22 0.00359 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 1.04 0.97 – 1.12 0.266 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.02 0.777 – 1.33 0.904 55 550 all phecode
010 Tuberculosis Infectious Diseases 1.15 0.984 – 1.35 0.0789 166 1659 all phecode
038 Septicemia Infectious Diseases 1.03 0.994 – 1.06 0.116 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 0.978 0.912 – 1.05 0.529 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 0.945 0.862 – 1.04 0.224 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 1.01 0.988 – 1.03 0.49 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.01 0.97 – 1.04 0.738 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 1 0.951 – 1.05 0.996 1641 16433 all phecode
041.4 E. coli Infectious Diseases 1 0.966 – 1.04 0.816 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 1.08 0.975 – 1.2 0.14 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.02 0.823 – 1.25 0.888 95 949 all phecode
054 Herpes simplex Infectious Diseases 1.01 0.876 – 1.16 0.929 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 0.981 0.902 – 1.07 0.654 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 1.04 0.814 – 1.32 0.775 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 0.927 0.777 – 1.1 0.394 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 0.974 0.858 – 1.11 0.69 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 1 0.884 – 1.14 0.946 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 0.975 0.883 – 1.08 0.616 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.07 0.904 – 1.26 0.447 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.05 0.868 – 1.26 0.631 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 1.02 0.958 – 1.09 0.501 1004 10036 all phecode
079 Viral infection Infectious Diseases 1.02 0.979 – 1.06 0.361 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 0.85 0.66 – 1.1 0.209 64 640 all phecode
080 Postoperative infection Infectious Diseases 0.999 0.968 – 1.03 0.93 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.01 0.973 – 1.06 0.517 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.04 0.83 – 1.3 0.746 71 709 all phecode
1000 Burns Injuries & Poisonings 1 0.921 – 1.09 0.93 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 0.964 0.909 – 1.02 0.227 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.01 0.982 – 1.04 0.488 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.07 0.953 – 1.21 0.241 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 1.01 0.958 – 1.07 0.675 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 0.885 0.777 – 1.01 0.0659 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 1.02 0.904 – 1.16 0.701 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.01 0.95 – 1.08 0.705 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 0.993 0.971 – 1.02 0.551 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 0.984 0.958 – 1.01 0.233 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.998 0.976 – 1.02 0.833 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 0.902 0.737 – 1.1 0.314 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.03 0.917 – 1.15 0.636 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.96 0.745 – 1.24 0.756 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 1.01 0.976 – 1.04 0.656 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.03 1.01 – 1.04 0.00148 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.04 0.925 – 1.18 0.489 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 1.05 0.93 – 1.19 0.427 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.883 0.699 – 1.12 0.299 74 756 all phecode
110.12 Althete's foot Infectious Diseases 1.1 0.923 – 1.31 0.289 141 1410 all phecode
112 Candidiasis Infectious Diseases 0.965 0.922 – 1.01 0.115 2126 21275 all phecode
117 Mycoses Infectious Diseases 1.04 0.922 – 1.18 0.508 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 0.994 0.852 – 1.16 0.943 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 1.23 0.978 – 1.54 0.0769 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 0.889 0.699 – 1.13 0.339 69 689 all phecode
134 Helminthiases Infectious Diseases 1.16 0.964 – 1.39 0.117 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.14 0.931 – 1.39 0.21 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.15 1 – 1.32 0.0504 205 2050 all phecode
145 Cancer of mouth Neoplasms 0.993 0.916 – 1.08 0.865 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 0.954 0.852 – 1.07 0.416 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 0.981 0.805 – 1.2 0.849 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.29 0.976 – 1.7 0.0739 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.02 0.938 – 1.11 0.664 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 0.975 0.855 – 1.11 0.701 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 1.04 0.918 – 1.18 0.528 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 1.15 0.869 – 1.52 0.329 57 570 all phecode
150 Cancer of esophagus Neoplasms 1.05 0.971 – 1.13 0.236 762 7630 all phecode
151 Cancer of stomach Neoplasms 0.998 0.916 – 1.09 0.96 569 5696 all phecode
153 Colorectal cancer Neoplasms 1.01 0.98 – 1.04 0.508 4580 45799 all phecode
153.2 Colon cancer Neoplasms 1 0.966 – 1.04 0.899 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.02 0.977 – 1.07 0.353 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.958 0.866 – 1.06 0.409 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.891 0.757 – 1.05 0.167 158 1580 all phecode
157 Pancreatic cancer Neoplasms 0.985 0.909 – 1.07 0.713 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.07 1.01 – 1.14 0.0251 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.02 0.991 – 1.05 0.184 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.968 0.84 – 1.12 0.654 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.965 0.835 – 1.12 0.631 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1 0.866 – 1.16 0.988 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 1.12 0.876 – 1.44 0.359 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 1.01 0.974 – 1.05 0.54 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.01 0.97 – 1.06 0.551 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.983 0.891 – 1.08 0.726 437 4364 all phecode
170.1 Bone cancer Neoplasms 1.02 0.853 – 1.22 0.826 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 0.993 0.888 – 1.11 0.901 331 3303 all phecode
172 Skin cancer Neoplasms 1.01 0.991 – 1.03 0.32 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.05 1.01 – 1.09 0.0217 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 1.05 1.01 – 1.09 0.0169 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1 0.981 – 1.02 0.945 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 0.968 0.893 – 1.05 0.423 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.04 0.893 – 1.2 0.638 181 1818 all phecode
174 Breast cancer Neoplasms 1.51 1.48 – 1.54 6.89e-413 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 1.51 1.49 – 1.54 4.35e-412 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.52 1.5 – 1.55 2.06e-400 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.41 1.17 – 1.71 0.000415 115 1148 all phecode
175 Acquired absence of breast Neoplasms 1.54 1.48 – 1.61 1.17e-88 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 1.04 0.99 – 1.08 0.127 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 1.04 0.919 – 1.17 0.549 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.02 0.977 – 1.07 0.331 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 1.12 1.06 – 1.19 9.44e-05 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 1.07 1.02 – 1.13 0.0128 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.1 1.03 – 1.17 0.00629 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.09 1.02 – 1.16 0.0146 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.02 0.91 – 1.15 0.708 305 3049 all phecode
185 Cancer of prostate Neoplasms 1.04 1.01 – 1.07 0.00441 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 1.05 0.951 – 1.16 0.347 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.04 0.819 – 1.33 0.731 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 1.03 0.91 – 1.16 0.675 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.06 0.867 – 1.29 0.586 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.984 0.953 – 1.02 0.31 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.04 0.972 – 1.1 0.282 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.02 0.961 – 1.09 0.458 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.27 0.982 – 1.63 0.0688 66 660 all phecode
189.2 Cancer of bladder Neoplasms 0.956 0.917 – 0.997 0.0355 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.96 0.918 – 1 0.0759 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.01 0.854 – 1.19 0.907 144 1439 all phecode
190 Cancer of eye Neoplasms 1.14 0.972 – 1.33 0.109 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.02 0.946 – 1.11 0.56 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 0.987 0.906 – 1.08 0.774 566 5650 all phecode
191.11 Cancer of brain Neoplasms 1 0.918 – 1.1 0.92 525 5240 all phecode
193 Thyroid cancer Neoplasms 1.01 0.905 – 1.12 0.893 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 0.888 0.719 – 1.1 0.271 95 949 all phecode
195 Cancer, suspected or other Neoplasms 1.06 1.04 – 1.07 1.42e-11 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.05 1.04 – 1.07 2.11e-10 16267 159497 all phecode
197 Chemotherapy Neoplasms 1.07 1.06 – 1.09 2.7e-21 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 1.13 1.11 – 1.16 2.38e-31 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.18 1.15 – 1.22 1.86e-32 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.07 1.02 – 1.12 0.00213 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.07 1.02 – 1.13 0.0085 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.08 1.03 – 1.12 0.000263 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.08 1 – 1.16 0.0435 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.18 1.13 – 1.23 4.73e-13 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.08 0.932 – 1.25 0.307 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.02 0.964 – 1.08 0.511 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 1.03 0.834 – 1.27 0.794 95 950 all phecode
200 Myeloproliferative disease Neoplasms 1.05 0.984 – 1.12 0.14 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 1.03 0.931 – 1.15 0.529 387 3867 all phecode
201 Hodgkin's disease Neoplasms 1.04 0.915 – 1.18 0.562 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.04 0.992 – 1.08 0.115 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.03 0.984 – 1.08 0.193 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 1.07 0.956 – 1.19 0.249 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 1.03 0.948 – 1.12 0.47 581 5824 all phecode
204 Leukemia Neoplasms 1.02 0.966 – 1.07 0.543 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 0.967 0.888 – 1.05 0.439 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.02 0.787 – 1.32 0.877 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.98 0.895 – 1.07 0.659 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 0.985 0.896 – 1.08 0.749 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.937 0.837 – 1.05 0.255 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.09 0.911 – 1.29 0.358 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 1.08 0.987 – 1.17 0.0981 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 1.01 0.997 – 1.03 0.119 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.01 0.942 – 1.07 0.855 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1 0.972 – 1.03 0.998 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.08 0.969 – 1.21 0.164 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.03 0.916 – 1.15 0.637 318 3187 all phecode
214 Lipoma Neoplasms 1.01 0.986 – 1.04 0.369 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.02 0.985 – 1.05 0.33 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.981 0.923 – 1.04 0.534 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 0.988 0.965 – 1.01 0.295 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.06 0.978 – 1.15 0.15 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.07 0.982 – 1.16 0.126 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 1.04 1.02 – 1.06 0.000424 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 1.04 1.02 – 1.06 0.000129 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.973 0.872 – 1.08 0.618 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 1.03 0.976 – 1.09 0.277 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.07 0.928 – 1.23 0.361 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 1.03 0.872 – 1.21 0.74 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.971 0.832 – 1.13 0.705 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 1.23 1.03 – 1.47 0.0258 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.24 0.982 – 1.57 0.0701 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.13 1.06 – 1.22 0.000559 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.14 1.06 – 1.23 0.000496 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.966 0.736 – 1.27 0.803 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.12 0.992 – 1.28 0.0669 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.965 0.899 – 1.03 0.312 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.927 0.799 – 1.08 0.319 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.976 0.877 – 1.08 0.648 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.976 0.868 – 1.1 0.68 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.99 0.94 – 1.04 0.692 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.987 0.946 – 1.03 0.539 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.09 1.01 – 1.19 0.0347 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.988 0.929 – 1.05 0.701 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.99 0.902 – 1.09 0.834 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.984 0.91 – 1.06 0.69 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.967 0.922 – 1.01 0.17 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 0.937 0.852 – 1.03 0.183 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.1 0.884 – 1.37 0.39 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 0.866 0.729 – 1.03 0.0984 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 0.992 0.975 – 1.01 0.354 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1 0.94 – 1.06 0.993 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.918 0.75 – 1.12 0.401 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.99 0.973 – 1.01 0.279 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 0.963 0.852 – 1.09 0.551 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.993 0.863 – 1.14 0.926 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.993 0.862 – 1.15 0.927 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 0.948 0.856 – 1.05 0.302 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 0.996 0.982 – 1.01 0.633 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.997 0.959 – 1.04 0.897 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.952 0.835 – 1.09 0.47 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.995 0.79 – 1.25 0.969 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.01 0.916 – 1.11 0.876 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.05 0.891 – 1.23 0.582 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.999 0.984 – 1.01 0.928 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.787 0.645 – 0.96 0.0183 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.973 0.84 – 1.13 0.711 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.937 0.877 – 1 0.0547 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.05 0.954 – 1.15 0.346 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 0.987 0.912 – 1.07 0.753 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.937 0.826 – 1.06 0.314 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.04 0.934 – 1.15 0.51 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.01 0.845 – 1.2 0.926 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.08 0.972 – 1.21 0.146 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.964 0.911 – 1.02 0.208 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 0.957 0.895 – 1.02 0.193 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.958 0.894 – 1.03 0.228 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.959 0.891 – 1.03 0.262 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.982 0.828 – 1.16 0.835 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.05 0.966 – 1.13 0.266 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.03 0.888 – 1.2 0.677 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.05 0.845 – 1.3 0.673 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.03 0.904 – 1.16 0.696 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.07 0.858 – 1.34 0.541 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.05 0.895 – 1.24 0.533 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.06 0.975 – 1.15 0.181 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.22 1.06 – 1.42 0.00756 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.13 0.925 – 1.37 0.237 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.3 1.04 – 1.63 0.0228 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.996 0.894 – 1.11 0.949 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.996 0.893 – 1.11 0.944 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.05 0.914 – 1.2 0.52 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.05 0.905 – 1.21 0.545 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 1.08 0.925 – 1.27 0.319 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.07 0.912 – 1.26 0.396 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.04 0.839 – 1.28 0.736 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 0.973 0.827 – 1.15 0.745 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.05 0.908 – 1.2 0.536 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 1.2 0.903 – 1.59 0.211 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 1.01 0.942 – 1.09 0.747 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 0.978 0.922 – 1.04 0.463 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.975 0.905 – 1.05 0.511 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.953 0.865 – 1.05 0.326 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.06 0.845 – 1.33 0.61 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.985 0.861 – 1.13 0.819 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 0.967 0.865 – 1.08 0.552 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.987 0.878 – 1.11 0.821 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.959 0.845 – 1.09 0.511 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.02 0.876 – 1.18 0.839 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.03 0.847 – 1.25 0.773 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.867 0.68 – 1.11 0.249 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.11 0.946 – 1.3 0.203 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.12 0.946 – 1.33 0.187 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.998 0.986 – 1.01 0.672 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.997 0.986 – 1.01 0.64 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.998 0.987 – 1.01 0.768 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.06 0.817 – 1.38 0.655 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.877 0.748 – 1.03 0.105 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.955 0.828 – 1.1 0.527 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.975 0.943 – 1.01 0.134 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 0.975 0.94 – 1.01 0.17 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.05 0.859 – 1.27 0.659 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.988 0.909 – 1.07 0.782 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.984 0.902 – 1.07 0.716 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.02 0.979 – 1.07 0.292 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 1.06 0.981 – 1.15 0.137 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.03 0.927 – 1.15 0.561 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.989 0.932 – 1.05 0.716 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.894 0.765 – 1.04 0.158 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.02 0.994 – 1.04 0.15 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.01 0.981 – 1.05 0.418 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.06 0.929 – 1.21 0.383 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 0.998 0.951 – 1.05 0.929 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.05 0.982 – 1.12 0.155 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.01 0.954 – 1.06 0.779 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.998 0.939 – 1.06 0.941 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 0.992 0.932 – 1.06 0.814 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 0.977 0.809 – 1.18 0.808 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.03 0.993 – 1.07 0.105 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 1.01 0.917 – 1.11 0.847 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 0.987 0.822 – 1.19 0.892 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1 0.936 – 1.07 0.966 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1 0.903 – 1.12 0.932 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.05 0.921 – 1.2 0.456 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.08 0.812 – 1.43 0.609 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.996 0.977 – 1.02 0.697 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 0.997 0.977 – 1.02 0.764 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 0.947 0.756 – 1.19 0.637 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.831 0.645 – 1.07 0.155 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.945 0.829 – 1.08 0.396 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 0.916 0.791 – 1.06 0.239 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.968 0.809 – 1.16 0.721 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.1 0.965 – 1.25 0.155 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 0.996 0.972 – 1.02 0.711 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.996 0.972 – 1.02 0.745 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.985 0.893 – 1.09 0.76 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 0.948 0.892 – 1.01 0.0901 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 0.94 0.883 – 1 0.0543 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 0.946 0.878 – 1.02 0.143 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.895 0.765 – 1.05 0.167 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 0.94 0.812 – 1.09 0.413 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 1.14 0.878 – 1.48 0.323 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.01 0.859 – 1.2 0.862 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.24 0.929 – 1.67 0.143 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.89 0.716 – 1.11 0.291 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 0.957 0.803 – 1.14 0.621 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.972 0.794 – 1.19 0.786 103 1059 all phecode
284 Aplastic anemia Hematopoietic 1.01 0.914 – 1.12 0.85 435 4357 all phecode
285 Other anemias Hematopoietic 0.999 0.98 – 1.02 0.901 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.896 0.793 – 1.01 0.0755 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.07 0.99 – 1.16 0.089 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.08 0.978 – 1.19 0.13 414 4147 all phecode
286 Coagulation defects Hematopoietic 1.02 0.957 – 1.1 0.493 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 1.07 0.976 – 1.18 0.145 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 1.02 0.831 – 1.24 0.87 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.03 0.914 – 1.16 0.628 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.15 0.882 – 1.49 0.309 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.18 0.954 – 1.45 0.128 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.98 0.884 – 1.09 0.708 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.01 0.965 – 1.07 0.566 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.16 0.967 – 1.39 0.112 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 0.856 0.651 – 1.13 0.266 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 1.01 0.961 – 1.07 0.651 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 0.978 0.883 – 1.08 0.667 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.05 0.832 – 1.31 0.703 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 1.08 1.04 – 1.11 1.22e-05 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 1.09 1.05 – 1.13 1.37e-06 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 1.09 1.05 – 1.13 2.48e-06 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 1.13 0.886 – 1.45 0.318 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.04 0.972 – 1.12 0.247 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.994 0.881 – 1.12 0.917 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 0.993 0.954 – 1.03 0.716 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 0.985 0.899 – 1.08 0.738 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.04 0.919 – 1.17 0.568 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1 0.812 – 1.24 0.987 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.986 0.941 – 1.03 0.565 1929 19281 all phecode
290.1 Dementias Mental Disorders 0.961 0.9 – 1.03 0.233 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 0.986 0.892 – 1.09 0.776 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 1.13 0.979 – 1.3 0.0959 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.03 0.951 – 1.12 0.469 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.07 0.84 – 1.35 0.599 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.02 0.949 – 1.09 0.6 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.07 0.901 – 1.28 0.433 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1 0.889 – 1.13 0.952 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 1.02 0.925 – 1.13 0.688 436 4376 all phecode
292 Neurological disorders Mental Disorders 1.01 0.979 – 1.04 0.586 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.991 0.941 – 1.04 0.746 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.955 0.823 – 1.11 0.539 190 1907 all phecode
292.3 Memory loss Mental Disorders 0.998 0.924 – 1.08 0.96 696 6978 all phecode
292.4 Altered mental status Mental Disorders 1.01 0.969 – 1.06 0.578 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 1.08 0.959 – 1.21 0.207 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 0.969 0.927 – 1.01 0.179 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.03 0.957 – 1.1 0.474 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.02 0.947 – 1.09 0.659 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 1.03 0.944 – 1.12 0.522 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 1.04 0.894 – 1.2 0.634 178 1780 all phecode
295.3 Psychosis Mental Disorders 0.935 0.799 – 1.09 0.406 169 1710 all phecode
296 Mood disorders Mental Disorders 1.01 0.996 – 1.03 0.123 12372 123822 all phecode
296.1 Bipolar Mental Disorders 1.07 1 – 1.13 0.0472 1059 10599 all phecode
296.2 Depression Mental Disorders 1.01 0.994 – 1.03 0.187 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 1.08 0.969 – 1.2 0.166 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.934 0.83 – 1.05 0.26 311 3070 all phecode
300 Anxiety disorders Mental Disorders 1.02 0.994 – 1.04 0.136 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 1.02 0.998 – 1.05 0.0674 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1.01 0.857 – 1.2 0.877 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1 0.931 – 1.08 0.915 707 7065 all phecode
300.13 Phobia Mental Disorders 0.951 0.868 – 1.04 0.278 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.972 0.816 – 1.16 0.745 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 1.03 0.795 – 1.35 0.799 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 1.11 0.921 – 1.33 0.277 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.883 0.732 – 1.07 0.194 113 1129 all phecode
301 Personality disorders Mental Disorders 0.881 0.788 – 0.984 0.0249 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.883 0.736 – 1.06 0.177 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.982 0.869 – 1.11 0.771 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.969 0.881 – 1.06 0.51 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 0.99 0.888 – 1.1 0.858 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 0.833 0.694 – 1 0.0494 123 1229 all phecode
304 Adjustment reaction Mental Disorders 1.04 0.922 – 1.17 0.534 293 2936 all phecode
305.2 Eating disorder Mental Disorders 0.948 0.772 – 1.16 0.611 90 900 all phecode
306 Other mental disorder Mental Disorders 1.01 0.996 – 1.02 0.165 28056 230087 all phecode
306.9 Tension headache Mental Disorders 1.06 0.949 – 1.19 0.298 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 0.927 0.738 – 1.16 0.514 76 770 all phecode
313.3 Autism Mental Disorders 0.972 0.73 – 1.29 0.844 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 0.965 0.864 – 1.08 0.53 351 3517 all phecode
315.1 Learning disorder Mental Disorders 0.925 0.788 – 1.09 0.343 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 0.84 0.672 – 1.05 0.124 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 1.01 0.978 – 1.03 0.704 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.11 0.851 – 1.44 0.448 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 0.996 0.978 – 1.01 0.64 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 0.994 0.973 – 1.02 0.608 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.05 0.982 – 1.13 0.148 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 1.01 0.999 – 1.03 0.0635 19359 185465 all phecode
320 Meningitis Neurological 0.949 0.861 – 1.05 0.292 444 4447 all phecode
323 Encephalitis Neurological 0.968 0.866 – 1.08 0.573 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 0.709 0.552 – 0.909 0.00679 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 0.97 0.86 – 1.09 0.619 292 2916 all phecode
327 Sleep disorders Neurological 0.945 0.89 – 1 0.061 1164 11659 all phecode
327.3 Sleep apnea Neurological 0.986 0.956 – 1.02 0.358 4428 44318 all phecode
327.4 Insomnia Neurological 1.04 0.898 – 1.21 0.574 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 1 0.849 – 1.18 0.987 136 1390 all phecode
331 Other cerebral degenerations Neurological 1.05 0.989 – 1.12 0.107 1142 11416 all phecode
331.1 Hydrocephalus Neurological 1.01 0.924 – 1.11 0.796 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 1.15 1.04 – 1.26 0.00687 430 4298 all phecode
332 Parkinson's disease Neurological 1.03 0.966 – 1.09 0.389 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.969 0.904 – 1.04 0.378 894 8954 all phecode
333.1 Essential tremor Neurological 0.953 0.832 – 1.09 0.494 216 2157 all phecode
333.2 Myoclonus Neurological 1.01 0.821 – 1.24 0.941 96 958 all phecode
333.4 Torsion dystonia Neurological 1.03 0.906 – 1.17 0.658 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 1.02 0.973 – 1.07 0.397 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 0.991 0.819 – 1.2 0.928 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 0.897 0.788 – 1.02 0.0989 245 2446 all phecode
335 Multiple sclerosis Neurological 0.989 0.935 – 1.05 0.689 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 1.09 0.96 – 1.23 0.187 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.15 0.909 – 1.45 0.248 72 719 all phecode
338 Pain Neurological 1.01 0.938 – 1.09 0.808 768 7692 all phecode
338.1 Acute pain Neurological 1.03 0.925 – 1.14 0.63 394 3937 all phecode
338.2 Chronic pain Neurological 0.977 0.881 – 1.08 0.653 380 3817 all phecode
339 Other headache syndromes Neurological 0.993 0.97 – 1.02 0.55 7819 78241 all phecode
340 Migraine Neurological 1.03 0.992 – 1.07 0.116 2860 28602 all phecode
340.1 Migrain with aura Neurological 1.03 0.898 – 1.19 0.653 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.948 0.833 – 1.08 0.414 252 2535 all phecode
342 Hemiplegia Neurological 0.957 0.908 – 1.01 0.103 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 1.08 0.91 – 1.28 0.389 145 1450 all phecode
344 Other paralytic syndromes Neurological 0.995 0.918 – 1.08 0.896 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.01 0.985 – 1.04 0.35 5023 50270 all phecode
345.1 Epilepsy Neurological 0.993 0.926 – 1.06 0.847 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 0.97 0.881 – 1.07 0.544 439 4385 all phecode
345.12 Partial epilepsy Neurological 0.965 0.854 – 1.09 0.567 277 2776 all phecode
345.3 Convulsions Neurological 1.05 1 – 1.09 0.0415 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.08 0.91 – 1.28 0.377 144 1438 all phecode
348 Other conditions of brain Neurological 1.02 0.945 – 1.1 0.646 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.06 0.933 – 1.2 0.373 268 2678 all phecode
348.4 Cerebral cysts Neurological 0.847 0.707 – 1.01 0.0713 133 1350 all phecode
348.7 Coma Neurological 1.04 0.932 – 1.16 0.5 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.04 0.915 – 1.19 0.536 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 1.06 0.957 – 1.18 0.261 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.06 0.945 – 1.18 0.337 342 3414 all phecode
350 Abnormal movement Neurological 0.99 0.951 – 1.03 0.612 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 0.909 0.848 – 0.975 0.00735 887 8852 all phecode
350.2 Abnormality of gait Neurological 1.01 0.963 – 1.07 0.62 1596 15969 all phecode
350.3 Lack of coordination Neurological 1.01 0.911 – 1.13 0.803 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.944 0.729 – 1.22 0.659 54 540 all phecode
351 Other peripheral nerve disorders Neurological 1.01 0.987 – 1.02 0.562 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 0.946 0.895 – 1 0.0507 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.02 0.926 – 1.12 0.691 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 0.917 0.856 – 0.983 0.0145 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 1.02 0.956 – 1.08 0.6 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 0.902 0.744 – 1.09 0.298 114 1138 all phecode
353.2 Nerve root lesions Neurological 1.08 0.83 – 1.39 0.582 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.13 0.956 – 1.33 0.152 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.04 0.98 – 1.1 0.212 1361 13648 all phecode
358 Myoneural disorders Neurological 0.921 0.801 – 1.06 0.248 211 2109 all phecode
358.1 Myasthenia gravis Neurological 0.881 0.76 – 1.02 0.0921 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.99 0.899 – 1.09 0.832 465 4646 all phecode
359.1 Muscular dystrophies Neurological 1.03 0.857 – 1.24 0.759 122 1219 all phecode
359.2 Myopathy Neurological 0.977 0.876 – 1.09 0.68 360 3597 all phecode
360 Disorders of the globe Sense Organs 0.976 0.874 – 1.09 0.667 337 3367 all phecode
360.2 Progressive myopia Sense Organs 0.904 0.794 – 1.03 0.125 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 0.987 0.952 – 1.02 0.488 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.996 0.943 – 1.05 0.9 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.97 0.771 – 1.22 0.795 68 680 all phecode
362 Other retinal disorders Sense Organs 1.02 0.989 – 1.06 0.198 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.04 0.996 – 1.09 0.0752 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.04 0.996 – 1.09 0.0767 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.928 0.789 – 1.09 0.363 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 1.01 0.826 – 1.24 0.911 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.03 0.959 – 1.1 0.439 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 1.05 0.904 – 1.21 0.534 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.921 0.737 – 1.15 0.466 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.901 0.747 – 1.09 0.279 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.03 0.883 – 1.21 0.691 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 0.987 0.775 – 1.26 0.916 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.04 0.96 – 1.13 0.325 647 6485 all phecode
364.1 Corneal opacity Sense Organs 0.997 0.805 – 1.24 0.981 90 910 all phecode
364.2 Corneal edema Sense Organs 0.952 0.759 – 1.19 0.667 79 800 all phecode
364.4 Corneal degenerations Sense Organs 1.04 0.9 – 1.2 0.614 201 2017 all phecode
364.41 Keratoconus Sense Organs 0.999 0.803 – 1.24 0.996 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 1.03 0.895 – 1.19 0.656 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 1.27 1.03 – 1.57 0.0235 100 1000 all phecode
365 Glaucoma Sense Organs 0.992 0.962 – 1.02 0.624 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 0.956 0.897 – 1.02 0.167 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 0.955 0.896 – 1.02 0.157 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 1 0.929 – 1.09 0.912 698 6996 all phecode
366 Cataract Sense Organs 1 0.986 – 1.02 0.963 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 1.14 0.88 – 1.46 0.328 69 700 all phecode
366.2 Senile cataract Sense Organs 0.999 0.976 – 1.02 0.916 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 1.01 0.83 – 1.24 0.896 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.01 0.97 – 1.05 0.611 2408 24092 all phecode
367.1 Myopia Sense Organs 1.01 0.955 – 1.07 0.686 1251 12519 all phecode
367.2 Astigmatism Sense Organs 0.996 0.856 – 1.16 0.954 190 1899 all phecode
367.8 Hypermetropia Sense Organs 0.939 0.827 – 1.07 0.332 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 1.02 0.946 – 1.1 0.584 719 7198 all phecode
368 Visual disturbances Sense Organs 1.01 0.973 – 1.05 0.585 2962 29648 all phecode
368.1 Amblyopia Sense Organs 1.09 0.994 – 1.19 0.0678 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.968 0.897 – 1.04 0.397 727 7288 all phecode
368.3 Anisometropia Sense Organs 1.11 0.945 – 1.31 0.199 154 1548 all phecode
368.4 Visual field defects Sense Organs 1.04 0.929 – 1.15 0.532 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 0.966 0.889 – 1.05 0.405 612 6115 all phecode
369 Infection of the eye Sense Organs 1.06 0.967 – 1.16 0.219 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 1.04 0.862 – 1.25 0.698 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 1 0.868 – 1.15 0.993 213 2128 all phecode
370 Keratitis Sense Organs 0.93 0.825 – 1.05 0.241 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 0.971 0.822 – 1.15 0.725 141 1408 all phecode
371 Inflammation of the eye Sense Organs 1 0.965 – 1.04 0.941 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.02 0.932 – 1.12 0.632 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 1.02 0.978 – 1.06 0.36 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 0.992 0.921 – 1.07 0.838 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 0.979 0.953 – 1.01 0.129 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 0.931 0.875 – 0.991 0.026 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 0.972 0.926 – 1.02 0.247 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 0.997 0.954 – 1.04 0.881 2204 22031 all phecode
375.2 Epiphora Sense Organs 1.04 0.967 – 1.11 0.324 898 8969 all phecode
376 Disorders of the orbit Sense Organs 1.08 0.873 – 1.34 0.474 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.96 0.862 – 1.07 0.455 361 3618 all phecode
377.1 Optic atrophy Sense Organs 1.01 0.776 – 1.31 0.955 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.18 0.988 – 1.42 0.0673 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.04 0.987 – 1.1 0.132 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.04 0.975 – 1.12 0.218 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.01 0.873 – 1.16 0.927 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 1.06 0.939 – 1.2 0.349 275 2755 all phecode
379 Other disorders of eye Sense Organs 0.99 0.957 – 1.02 0.559 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 0.982 0.929 – 1.04 0.523 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.984 0.938 – 1.03 0.498 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.2 0.942 – 1.54 0.139 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.05 0.946 – 1.16 0.362 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.1 0.944 – 1.28 0.221 169 1690 all phecode
380 Disorders of external ear Sense Organs 0.987 0.91 – 1.07 0.752 642 6413 all phecode
380.1 Otitis externa Sense Organs 1.03 0.942 – 1.13 0.51 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 1 0.899 – 1.12 0.946 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.975 0.933 – 1.02 0.26 2150 21493 all phecode
381.1 Otitis media Sense Organs 0.973 0.927 – 1.02 0.266 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1 0.936 – 1.08 0.908 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 1.01 0.869 – 1.17 0.924 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 0.844 0.722 – 0.986 0.0327 171 1709 all phecode
381.9 Otorrhea Sense Organs 1.06 0.933 – 1.19 0.39 281 2807 all phecode
382 Otalgia Sense Organs 1.06 0.941 – 1.19 0.344 308 3084 all phecode
383 Otosclerosis Sense Organs 1 0.891 – 1.12 0.992 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 0.962 0.908 – 1.02 0.188 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 0.97 0.91 – 1.03 0.348 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.05 0.973 – 1.13 0.222 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 1.04 0.952 – 1.13 0.416 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.02 0.896 – 1.17 0.745 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.967 0.921 – 1.02 0.186 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 0.913 0.839 – 0.993 0.0347 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 0.99 0.89 – 1.1 0.858 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 1.03 0.954 – 1.11 0.476 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.02 0.986 – 1.05 0.294 4582 45806 all phecode
388 Other disorders of ear Sense Organs 1.1 0.947 – 1.27 0.217 202 2017 all phecode
389 Hearing loss Sense Organs 1 0.97 – 1.03 0.948 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 1.03 0.936 – 1.13 0.54 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 0.916 0.831 – 1.01 0.0746 450 4497 all phecode
389.4 Tinnitus Sense Organs 1.1 1.01 – 1.2 0.0311 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.01 0.982 – 1.04 0.451 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 1.03 0.989 – 1.07 0.17 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 1 0.948 – 1.06 0.902 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 0.945 0.888 – 1.01 0.0761 1058 10566 all phecode
395 Heart valve disorders Circulatory System 1.01 0.981 – 1.04 0.447 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.03 0.987 – 1.06 0.201 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.957 0.848 – 1.08 0.482 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.05 0.86 – 1.27 0.654 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.815 0.667 – 0.995 0.0449 97 970 all phecode
395.6 Heart valve replaced Circulatory System 1.04 0.987 – 1.1 0.141 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 0.986 0.925 – 1.05 0.67 1048 10468 all phecode
401 Hypertension Circulatory System 1.01 0.997 – 1.01 0.188 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 1.01 0.997 – 1.01 0.208 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.01 0.962 – 1.06 0.732 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 1.04 0.931 – 1.16 0.501 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.999 0.948 – 1.05 0.956 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 0.995 0.841 – 1.18 0.957 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 0.985 0.934 – 1.04 0.576 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 0.989 0.977 – 1 0.0626 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.99 0.962 – 1.02 0.483 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 0.981 0.963 – 1 0.0499 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 0.996 0.979 – 1.01 0.605 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 0.985 0.971 – 1 0.0473 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.07 0.988 – 1.15 0.0992 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.992 0.975 – 1.01 0.322 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.971 0.915 – 1.03 0.335 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 0.964 0.918 – 1.01 0.137 1823 18228 all phecode
414.2 ASCVD Circulatory System 0.935 0.736 – 1.19 0.582 72 719 all phecode
415 Pulmonary heart disease Circulatory System 1.01 0.978 – 1.04 0.567 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.873 0.693 – 1.1 0.251 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.988 0.91 – 1.07 0.78 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.01 0.922 – 1.12 0.764 448 4475 all phecode
416 Cardiomegaly Circulatory System 0.995 0.957 – 1.04 0.818 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 1.01 0.994 – 1.02 0.355 28599 270106 all phecode
418.1 Precordial pain Circulatory System 1.01 0.978 – 1.05 0.494 3551 35541 all phecode
420 Carditis Circulatory System 1.01 0.963 – 1.05 0.775 2106 21053 all phecode
420.1 Myocarditis Circulatory System 1.17 0.969 – 1.41 0.104 127 1267 all phecode
420.2 Pericarditis Circulatory System 0.988 0.935 – 1.04 0.679 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 1.01 0.885 – 1.16 0.849 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 0.947 0.782 – 1.15 0.578 113 1129 all phecode
420.3 Endocarditis Circulatory System 0.997 0.925 – 1.08 0.944 719 7194 all phecode
425 Cardiomyopathy Circulatory System 0.997 0.942 – 1.06 0.931 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.979 0.923 – 1.04 0.477 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.07 0.894 – 1.28 0.464 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.03 0.882 – 1.21 0.674 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 1.16 0.902 – 1.49 0.248 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 0.995 0.971 – 1.02 0.681 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 0.983 0.94 – 1.03 0.449 2114 21162 all phecode
426.21 First degree AV block Circulatory System 0.995 0.932 – 1.06 0.892 986 9867 all phecode
426.23 Second degree AV block Circulatory System 0.973 0.885 – 1.07 0.581 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 0.952 0.875 – 1.04 0.257 587 5868 all phecode
426.25 Other heart block Circulatory System 1.11 0.936 – 1.32 0.226 131 1318 all phecode
426.3 Bundle branch block Circulatory System 1.01 0.979 – 1.05 0.437 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 1 0.95 – 1.06 0.958 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 1.02 0.969 – 1.07 0.484 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.1 0.96 – 1.26 0.169 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 0.972 0.746 – 1.27 0.832 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.987 0.947 – 1.03 0.527 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.994 0.952 – 1.04 0.779 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 1 0.991 – 1.02 0.54 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.03 0.991 – 1.07 0.137 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.05 1 – 1.09 0.0316 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.01 0.946 – 1.08 0.724 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1 0.983 – 1.02 0.977 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.981 0.946 – 1.02 0.288 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1 0.947 – 1.07 0.871 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.03 0.926 – 1.15 0.566 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 1.01 0.947 – 1.08 0.743 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1 0.94 – 1.07 0.896 952 9541 all phecode
427.6 Premature beats Circulatory System 1 0.916 – 1.09 0.993 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 0.988 0.82 – 1.19 0.897 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 1.05 1 – 1.1 0.0348 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.02 0.922 – 1.13 0.7 402 4029 all phecode
427.9 Palpitations Circulatory System 1.02 0.985 – 1.05 0.274 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1 0.975 – 1.03 0.885 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1 0.956 – 1.05 0.991 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 1.01 0.977 – 1.04 0.65 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.03 0.957 – 1.12 0.403 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 1.16 0.89 – 1.52 0.27 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.05 0.959 – 1.15 0.294 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 0.988 0.852 – 1.15 0.873 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 0.983 0.937 – 1.03 0.469 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.976 0.91 – 1.05 0.504 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1 0.928 – 1.08 0.989 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 1.01 0.888 – 1.14 0.937 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 0.998 0.976 – 1.02 0.869 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.976 0.92 – 1.04 0.434 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 0.963 0.844 – 1.1 0.581 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.972 0.941 – 1 0.0748 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.956 0.909 – 1.01 0.0823 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 0.982 0.946 – 1.02 0.352 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 0.988 0.946 – 1.03 0.604 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 1.01 0.911 – 1.12 0.863 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.973 0.919 – 1.03 0.343 1279 12783 all phecode
440 Atherosclerosis Circulatory System 0.992 0.938 – 1.05 0.789 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.828 0.682 – 1 0.0552 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1 0.93 – 1.08 0.975 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 0.954 0.845 – 1.08 0.444 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 0.987 0.909 – 1.07 0.753 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.998 0.885 – 1.13 0.979 283 2827 all phecode
442 Other aneurysm Circulatory System 0.982 0.937 – 1.03 0.452 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 0.986 0.934 – 1.04 0.611 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.982 0.917 – 1.05 0.59 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.06 0.865 – 1.29 0.584 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.965 0.825 – 1.13 0.659 169 1696 all phecode
442.4 Arterial dissection Circulatory System 0.785 0.597 – 1.03 0.0815 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 0.956 0.827 – 1.1 0.537 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 0.994 0.962 – 1.03 0.729 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 1 0.94 – 1.06 0.988 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.844 0.76 – 0.937 0.00147 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1 0.967 – 1.04 0.97 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.999 0.959 – 1.04 0.968 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 0.993 0.928 – 1.06 0.837 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.949 0.87 – 1.04 0.24 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.988 0.919 – 1.06 0.755 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 0.94 0.81 – 1.09 0.418 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 1.02 0.918 – 1.13 0.728 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 0.92 0.803 – 1.05 0.224 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.04 0.979 – 1.1 0.226 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 1.04 0.969 – 1.11 0.29 868 8712 all phecode
448 Disease of capillaries Circulatory System 1.1 0.931 – 1.3 0.257 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.16 1.08 – 1.26 8.74e-05 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.994 0.962 – 1.03 0.712 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.993 0.96 – 1.03 0.7 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 1.02 0.937 – 1.11 0.628 564 5645 all phecode
454 Varicose veins Circulatory System 1.02 1 – 1.04 0.0143 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1.02 1 – 1.04 0.0288 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.96 0.884 – 1.04 0.325 624 6325 all phecode
455 Hemorrhoids Circulatory System 0.999 0.985 – 1.01 0.858 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.983 0.846 – 1.14 0.819 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.96 0.779 – 1.18 0.705 97 967 all phecode
458 Hypotension Circulatory System 1.02 0.989 – 1.04 0.237 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 1.03 0.969 – 1.09 0.383 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 0.969 0.849 – 1.11 0.637 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 1.02 0.98 – 1.05 0.4 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 1 0.985 – 1.02 0.921 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 1.14 0.964 – 1.35 0.125 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 0.999 0.983 – 1.02 0.92 16103 159422 all phecode
464 Acute sinusitis Respiratory 1.12 0.963 – 1.3 0.142 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.04 0.998 – 1.09 0.0635 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 1.09 1.02 – 1.18 0.015 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.871 0.744 – 1.02 0.0886 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.984 0.955 – 1.01 0.288 4654 46553 all phecode
471 Nasal polyps Respiratory 0.997 0.962 – 1.03 0.881 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.974 0.913 – 1.04 0.436 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1.01 0.97 – 1.05 0.624 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 1.06 0.864 – 1.29 0.587 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.05 0.926 – 1.2 0.436 264 2647 all phecode
473.4 Voice disturbance Respiratory 1.01 0.946 – 1.07 0.814 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 1 0.952 – 1.05 0.989 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 1 0.916 – 1.09 0.995 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.03 0.966 – 1.09 0.39 1122 11199 all phecode
475 Chronic sinusitis Respiratory 0.99 0.951 – 1.03 0.626 2589 25882 all phecode
476 Allergic rhinitis Respiratory 0.964 0.905 – 1.03 0.256 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.01 0.973 – 1.06 0.503 2447 24452 all phecode
478 Throat pain Respiratory 0.94 0.847 – 1.04 0.249 377 3789 all phecode
479 Other upper respiratory disease Respiratory 1 0.972 – 1.04 0.811 4074 40737 all phecode
480 Pneumonia Respiratory 1 0.984 – 1.02 0.706 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 1 0.977 – 1.03 0.906 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.01 0.984 – 1.04 0.448 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.13 0.912 – 1.39 0.269 93 929 all phecode
480.2 Viral pneumonia Respiratory 1.07 0.848 – 1.36 0.557 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.1 0.902 – 1.34 0.349 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.04 0.963 – 1.11 0.343 794 7951 all phecode
481 Influenza Respiratory 0.997 0.889 – 1.12 0.955 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.03 0.886 – 1.19 0.738 193 1930 all phecode
495 Asthma Respiratory 1 0.989 – 1.01 0.799 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 1.09 0.953 – 1.24 0.214 250 2510 all phecode
496 Chronic airway obstruction Respiratory 1.01 0.988 – 1.03 0.429 10424 101546 all phecode
496.1 Emphysema Respiratory 1.01 0.962 – 1.06 0.691 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 1.01 0.976 – 1.05 0.495 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.01 0.969 – 1.05 0.703 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 1 0.957 – 1.05 0.881 1885 18859 all phecode
497 Bronchitis Respiratory 1.07 0.982 – 1.16 0.125 626 6267 all phecode
500 Lung disease due to external agents Respiratory 1.07 0.964 – 1.18 0.215 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.942 0.753 – 1.18 0.602 79 784 all phecode
500.2 Pneumoconiosis Respiratory 1.07 0.939 – 1.22 0.311 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.05 0.968 – 1.14 0.243 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.04 0.973 – 1.12 0.24 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 0.924 0.842 – 1.01 0.0936 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.1 0.984 – 1.24 0.0923 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.03 0.783 – 1.34 0.856 61 610 all phecode
506 Empyema and pneumothorax Respiratory 1.01 0.947 – 1.07 0.843 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 1.01 0.988 – 1.04 0.289 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.01 0.964 – 1.06 0.688 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.01 0.972 – 1.05 0.561 2599 26031 all phecode
509.1 Respiratory failure Respiratory 1.02 0.978 – 1.07 0.31 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 1.01 0.963 – 1.06 0.668 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 1.01 0.854 – 1.2 0.903 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.925 0.834 – 1.03 0.145 386 3863 all phecode
510 Other diseases of lung Respiratory 1.02 0.948 – 1.1 0.574 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 1.03 1 – 1.05 0.0176 9031 90349 all phecode
512.1 Wheezing Respiratory 1.04 0.904 – 1.2 0.583 220 2196 all phecode
512.2 Painful respiration Respiratory 0.92 0.799 – 1.06 0.253 207 2075 all phecode
512.7 Shortness of breath Respiratory 1.04 1.01 – 1.07 0.00534 5842 58498 all phecode
512.8 Cough Respiratory 0.996 0.959 – 1.04 0.842 2866 28642 all phecode
512.9 Other dyspnea Respiratory 1.08 1.01 – 1.16 0.02 914 9124 all phecode
513 Respiratory abnormalities Respiratory 1.05 0.963 – 1.14 0.282 611 6112 all phecode
513.3 Hypoventilation Respiratory 0.949 0.754 – 1.19 0.656 83 830 all phecode
513.4 Hyperventilation Respiratory 1.09 0.964 – 1.24 0.169 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 0.92 0.777 – 1.09 0.329 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 1.04 0.995 – 1.08 0.0871 2465 24673 all phecode
516 Abnormal sputum Respiratory 1.01 0.962 – 1.05 0.815 2132 21335 all phecode
516.1 Hemoptysis Respiratory 0.998 0.954 – 1.04 0.919 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.01 0.985 – 1.03 0.592 9366 93681 all phecode
519.2 Respiratory complications Respiratory 1.07 0.953 – 1.2 0.253 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.01 0.987 – 1.03 0.437 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.989 0.879 – 1.11 0.852 303 3049 all phecode
520 Disorders of tooth development Digestive 1.03 0.981 – 1.08 0.25 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.1 0.842 – 1.44 0.479 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 1.02 0.974 – 1.06 0.455 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 0.998 0.962 – 1.04 0.932 3016 30245 all phecode
521.1 Dental caries Digestive 0.998 0.962 – 1.04 0.936 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.03 0.981 – 1.08 0.231 1774 17750 all phecode
522.5 Periapical abscess Digestive 1.02 0.962 – 1.08 0.486 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 1.01 0.958 – 1.06 0.762 1681 16812 all phecode
523.1 Gingivitis Digestive 1.01 0.828 – 1.22 0.953 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.04 0.977 – 1.1 0.235 1165 11650 all phecode
523.31 Acute periodontitis Digestive 1.02 0.938 – 1.1 0.694 666 6667 all phecode
523.32 Chronic periodontitis Digestive 1.04 0.955 – 1.14 0.359 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 1 0.892 – 1.12 0.998 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.01 0.894 – 1.13 0.903 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.02 0.983 – 1.06 0.268 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.03 0.801 – 1.32 0.82 72 720 all phecode
526 Diseases of the jaws Digestive 1.05 0.981 – 1.12 0.165 928 9279 all phecode
526.1 Cysts of the jaws Digestive 1 0.899 – 1.12 0.951 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.947 0.735 – 1.22 0.672 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.09 0.953 – 1.24 0.214 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.1 0.959 – 1.25 0.179 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 1.01 0.834 – 1.22 0.925 110 1098 all phecode
526.9 Jaw disease NOS Digestive 1.09 0.95 – 1.24 0.225 233 2329 all phecode
527 Diseases of the salivary glands Digestive 1 0.925 – 1.08 0.987 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 0.934 0.75 – 1.16 0.544 84 838 all phecode
527.2 Sialoadenitis Digestive 1.07 0.961 – 1.19 0.216 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 0.959 0.742 – 1.24 0.749 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 0.814 0.675 – 0.981 0.0305 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.03 0.999 – 1.07 0.0613 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 1.1 0.997 – 1.2 0.0579 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.1 0.996 – 1.22 0.0593 389 3884 all phecode
528.12 Oral aphthae Digestive 1.1 0.878 – 1.39 0.4 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.09 0.933 – 1.27 0.279 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 0.978 0.811 – 1.18 0.819 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 0.969 0.783 – 1.2 0.768 94 940 all phecode
528.5 Diseases of lips Digestive 1.07 0.988 – 1.16 0.0973 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 0.9 0.799 – 1.01 0.0824 308 3079 all phecode
528.7 Sialolithiasis Digestive 1 0.894 – 1.12 0.976 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 1.02 0.96 – 1.08 0.564 1232 12312 all phecode
529.1 Glossitis Digestive 1.07 0.946 – 1.2 0.293 299 2986 all phecode
530 Diseases of esophagus Digestive 1.01 0.998 – 1.02 0.0922 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.01 0.997 – 1.02 0.157 31253 272429 all phecode
530.11 GERD Digestive 1.01 1 – 1.03 0.0391 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 0.999 0.971 – 1.03 0.928 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 1.01 0.985 – 1.03 0.602 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.966 0.918 – 1.02 0.176 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.06 1.01 – 1.11 0.0256 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 0.966 0.891 – 1.05 0.407 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.12 0.946 – 1.31 0.195 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.979 0.876 – 1.09 0.71 341 3416 all phecode
530.9 Heartburn Digestive 1.01 0.965 – 1.06 0.69 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.979 0.956 – 1 0.0948 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.99 0.913 – 1.07 0.805 637 6374 all phecode
531.2 Gastric ulcer Digestive 0.979 0.948 – 1.01 0.204 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 0.966 0.93 – 1 0.0674 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 0.958 0.869 – 1.06 0.394 427 4268 all phecode
532 Dysphagia Digestive 0.995 0.97 – 1.02 0.722 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 0.985 0.973 – 0.998 0.0185 28078 261548 all phecode
535.1 Acute gastritis Digestive 1 0.943 – 1.06 0.962 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 0.868 0.778 – 0.968 0.011 370 3687 all phecode
535.6 Duodenitis Digestive 0.968 0.946 – 0.991 0.00695 7592 75928 all phecode
535.8 Other specified gastritis Digestive 1.01 0.985 – 1.03 0.515 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.03 0.858 – 1.24 0.749 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.926 0.813 – 1.05 0.248 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 0.99 0.955 – 1.03 0.564 3391 33907 all phecode
540 Appendiceal conditions Digestive 1.02 0.983 – 1.06 0.304 3088 30890 all phecode
540.1 Appendicitis Digestive 1.01 0.974 – 1.05 0.531 2895 28963 all phecode
540.11 Acute appendicitis Digestive 0.999 0.96 – 1.04 0.965 2601 26019 all phecode
550 Abdominal hernia Digestive 1 0.993 – 1.01 0.621 45429 282640 all phecode
550.1 Inguinal hernia Digestive 1 0.983 – 1.02 0.984 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 1.01 0.994 – 1.02 0.279 26494 238953 all phecode
550.3 Femoral hernia Digestive 0.94 0.867 – 1.02 0.127 651 6504 all phecode
550.4 Umbilical hernia Digestive 0.945 0.914 – 0.978 0.00111 3705 37072 all phecode
550.5 Ventral hernia Digestive 0.982 0.948 – 1.02 0.309 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.03 1 – 1.07 0.0371 4444 44442 all phecode
555.1 Regional enteritis Digestive 0.98 0.933 – 1.03 0.428 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 1.06 1.02 – 1.1 0.00189 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.07 0.984 – 1.17 0.111 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 0.981 0.921 – 1.04 0.549 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 1.01 0.933 – 1.09 0.798 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.924 0.82 – 1.04 0.19 299 2987 all phecode
557.1 Celiac disease Digestive 0.878 0.837 – 0.921 9.4e-08 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 1.01 0.994 – 1.03 0.216 15492 155105 all phecode
559 Ileostomy status Digestive 1.04 0.985 – 1.09 0.163 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.03 0.995 – 1.06 0.0936 3936 39337 all phecode
560.1 Paralytic ileus Digestive 1 0.918 – 1.1 0.942 523 5231 all phecode
560.2 Impaction of intestine Digestive 0.907 0.798 – 1.03 0.137 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.04 0.969 – 1.12 0.265 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 1.03 0.997 – 1.07 0.0695 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 1.02 1 – 1.04 0.0126 15772 157686 all phecode
561.1 Diarrhea Digestive 0.943 0.858 – 1.04 0.221 466 4653 all phecode
561.2 Flatulence Digestive 1.09 1.03 – 1.14 0.00121 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 1.01 0.995 – 1.02 0.216 26714 211692 all phecode
562.1 Diverticulosis Digestive 1.01 0.995 – 1.02 0.213 26672 211642 all phecode
563 Constipation Digestive 1.01 0.986 – 1.03 0.543 10314 103140 all phecode
564 Functional digestive disorders Digestive 1 0.988 – 1.02 0.763 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.01 0.982 – 1.04 0.487 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.04 0.992 – 1.1 0.0965 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 0.993 0.976 – 1.01 0.388 15186 151648 all phecode
565 Anal and rectal conditions Digestive 1.01 0.994 – 1.03 0.223 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 1.02 0.996 – 1.04 0.103 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 0.997 0.932 – 1.07 0.931 929 9293 all phecode
568 Other disorders of peritoneum Digestive 1.01 0.974 – 1.05 0.603 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.01 0.975 – 1.05 0.543 3101 30987 all phecode
569 Other disorders of intestine Digestive 0.987 0.956 – 1.02 0.438 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.987 0.835 – 1.17 0.876 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 1.02 0.928 – 1.12 0.686 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.01 0.972 – 1.05 0.627 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.02 0.967 – 1.07 0.522 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.852 0.703 – 1.03 0.102 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 0.906 0.794 – 1.03 0.14 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.02 0.959 – 1.09 0.476 976 9804 all phecode
571.81 Portal hypertension Digestive 1.03 0.938 – 1.12 0.577 528 5285 all phecode
572 Ascites (non malignant) Digestive 1.03 0.975 – 1.08 0.306 1544 15454 all phecode
573 Other disorders of liver Digestive 0.992 0.941 – 1.05 0.758 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 0.922 0.745 – 1.14 0.455 96 960 all phecode
573.3 Hepatomegaly Digestive 1.06 0.939 – 1.19 0.365 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 1.01 0.947 – 1.09 0.693 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 1 0.97 – 1.04 0.797 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.04 0.903 – 1.2 0.579 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.02 1 – 1.04 0.0147 15607 156123 all phecode
574.1 Cholelithiasis Digestive 1.01 0.995 – 1.03 0.176 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.997 0.945 – 1.05 0.897 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.01 0.98 – 1.04 0.597 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 1.04 0.996 – 1.08 0.0776 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.04 1 – 1.08 0.0424 2748 27523 all phecode
575 Other biliary tract disease Digestive 0.989 0.957 – 1.02 0.512 3867 38724 all phecode
575.1 Cholangitis Digestive 0.995 0.907 – 1.09 0.915 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 0.948 0.88 – 1.02 0.154 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 1.06 0.966 – 1.17 0.214 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 0.982 0.93 – 1.04 0.507 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 1.03 0.967 – 1.1 0.351 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.997 0.894 – 1.11 0.957 348 3488 all phecode
577 Diseases of pancreas Digestive 1.01 0.973 – 1.05 0.554 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 1 0.957 – 1.05 0.945 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 0.976 0.891 – 1.07 0.601 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.976 0.878 – 1.08 0.653 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.996 – 1.02 0.158 20626 206278 all phecode
578.1 Hematemesis Digestive 1.03 0.986 – 1.08 0.172 1958 19564 all phecode
578.2 Blood in stool Digestive 1.01 0.966 – 1.05 0.788 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.01 0.991 – 1.03 0.32 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.01 0.982 – 1.04 0.489 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.03 0.981 – 1.09 0.215 1548 15498 all phecode
579.2 Splenomegaly Digestive 1.02 0.921 – 1.12 0.739 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.02 0.974 – 1.08 0.351 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.964 0.915 – 1.02 0.173 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 0.986 0.926 – 1.05 0.658 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.917 0.72 – 1.17 0.48 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.781 0.657 – 0.927 0.00482 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.01 0.94 – 1.08 0.826 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.896 0.815 – 0.985 0.0233 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.95 0.836 – 1.08 0.429 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.949 0.838 – 1.08 0.411 253 2529 all phecode
585 Renal failure Genitourinary 1.01 0.981 – 1.03 0.648 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 0.999 0.969 – 1.03 0.969 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 1 0.95 – 1.06 0.933 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1 0.966 – 1.05 0.809 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 1.01 0.918 – 1.11 0.876 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.04 1 – 1.07 0.0472 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.994 0.861 – 1.15 0.932 208 2089 all phecode
586.11 Small kidney Genitourinary 0.996 0.854 – 1.16 0.959 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.03 0.976 – 1.1 0.252 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.11 0.894 – 1.39 0.335 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.01 0.943 – 1.08 0.79 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 0.944 0.85 – 1.05 0.284 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 0.972 0.789 – 1.2 0.792 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 0.776 0.639 – 0.942 0.0103 116 1158 all phecode
590 Pyelonephritis Genitourinary 1.07 1.01 – 1.13 0.0207 1328 13285 all phecode
591 Urinary tract infection Genitourinary 1.01 0.995 – 1.03 0.167 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 1.02 0.984 – 1.06 0.256 2966 29661 all phecode
592.1 Cystitis Genitourinary 1.02 0.983 – 1.06 0.277 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 0.98 0.824 – 1.16 0.818 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 1.03 0.963 – 1.11 0.366 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 1.03 0.903 – 1.17 0.667 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1 0.857 – 1.17 0.986 165 1662 all phecode
593 Hematuria Genitourinary 1.01 0.992 – 1.02 0.316 16068 160204 all phecode
594 Urinary calculus Genitourinary 1.02 0.995 – 1.05 0.121 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 1.02 0.985 – 1.06 0.26 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 0.958 0.891 – 1.03 0.256 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 1.03 0.988 – 1.07 0.164 2401 24024 all phecode
594.8 Renal colic Genitourinary 1.04 0.991 – 1.08 0.12 2050 20500 all phecode
595 Hydronephrosis Genitourinary 0.984 0.939 – 1.03 0.491 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 0.995 0.975 – 1.02 0.658 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 1.02 0.976 – 1.07 0.355 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 0.982 0.934 – 1.03 0.478 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.01 0.976 – 1.04 0.626 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.991 0.956 – 1.03 0.615 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 0.843 0.674 – 1.05 0.135 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.01 0.972 – 1.04 0.75 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.06 0.95 – 1.19 0.283 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.999 0.984 – 1.01 0.874 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 0.872 0.743 – 1.02 0.0941 166 1670 all phecode
599.2 Retention of urine Genitourinary 1.01 0.989 – 1.04 0.287 6718 67168 all phecode
599.3 Dysuria Genitourinary 1.04 0.984 – 1.11 0.155 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 0.996 0.975 – 1.02 0.731 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.02 0.984 – 1.05 0.324 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 1.12 0.92 – 1.37 0.256 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.12 0.866 – 1.46 0.38 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 1.01 0.961 – 1.06 0.767 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 0.997 0.978 – 1.02 0.794 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 1.01 0.966 – 1.06 0.656 2081 20818 all phecode
601.1 Prostatitis Genitourinary 0.992 0.942 – 1.05 0.774 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 1.03 0.901 – 1.18 0.671 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 0.979 0.915 – 1.05 0.55 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 0.966 0.754 – 1.24 0.782 59 588 all phecode
601.4 Balanoposthitis Genitourinary 1.1 0.977 – 1.24 0.114 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1 0.892 – 1.13 0.975 303 3019 all phecode
602 Other disorders of prostate Genitourinary 0.995 0.94 – 1.05 0.851 1341 13408 all phecode
603 Other disorders of testis Genitourinary 1.03 0.982 – 1.07 0.247 2150 21512 all phecode
603.1 Hydrocele Genitourinary 1.05 0.995 – 1.11 0.0744 1339 13402 all phecode
604 Disorders of penis Genitourinary 0.997 0.962 – 1.03 0.848 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.01 0.968 – 1.05 0.762 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 1 0.886 – 1.13 0.983 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 1 0.963 – 1.04 0.961 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.03 0.898 – 1.19 0.64 214 2138 all phecode
609.1 Infertility, male Genitourinary 0.879 0.685 – 1.13 0.31 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 1.07 0.915 – 1.26 0.389 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 1.19 1.15 – 1.24 4.41e-17 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 1.15 1.08 – 1.23 4.42e-05 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.23 1.1 – 1.39 0.000403 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 1.18 1.05 – 1.33 0.00532 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 1.2 1.14 – 1.27 5e-11 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.13 1.05 – 1.23 0.00148 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.16 1.1 – 1.22 4.06e-08 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 1.44 1.1 – 1.88 0.00753 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 1.15 1.09 – 1.21 3.97e-07 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.12 1.05 – 1.2 0.000965 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.12 1.05 – 1.21 0.00123 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 1.1 0.871 – 1.38 0.433 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 1.16 1.1 – 1.22 1.98e-08 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.12 1.03 – 1.2 0.0052 720 7210 all phecode
613.5 Mastodynia Genitourinary 1.14 0.898 – 1.44 0.29 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 1.12 1.03 – 1.21 0.00582 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 1.35 1.2 – 1.51 3.26e-07 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 1.07 0.931 – 1.23 0.332 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.993 0.967 – 1.02 0.636 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.993 0.954 – 1.03 0.745 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.978 0.911 – 1.05 0.546 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.862 0.674 – 1.1 0.238 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.967 0.876 – 1.07 0.499 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.93 0.833 – 1.04 0.196 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1 0.886 – 1.13 0.997 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.997 0.958 – 1.04 0.886 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.968 0.914 – 1.02 0.257 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.97 0.878 – 1.07 0.551 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.07 0.991 – 1.15 0.0839 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.866 0.763 – 0.982 0.0245 274 2737 all phecode
615 Endometriosis Genitourinary 1.01 0.98 – 1.05 0.451 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 0.999 0.886 – 1.13 0.985 304 3037 all phecode
618 Genital prolapse Genitourinary 1 0.983 – 1.02 0.862 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1 0.976 – 1.02 0.983 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.987 0.96 – 1.02 0.363 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.828 0.756 – 0.906 4.54e-05 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.04 0.962 – 1.12 0.324 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.993 0.971 – 1.01 0.505 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.01 0.938 – 1.09 0.752 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 0.971 0.937 – 1.01 0.103 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.988 0.951 – 1.03 0.545 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.02 0.971 – 1.07 0.432 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.02 0.961 – 1.07 0.587 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 1.03 0.81 – 1.3 0.823 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 1.1 1.03 – 1.17 0.00225 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 1.05 1.03 – 1.07 2.56e-06 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 1.05 1.02 – 1.07 0.000139 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 1.05 1.02 – 1.09 0.00454 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.08 1.02 – 1.14 0.0127 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 0.962 0.895 – 1.03 0.29 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.997 0.872 – 1.14 0.966 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.974 0.885 – 1.07 0.595 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 0.982 0.956 – 1.01 0.188 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.978 0.941 – 1.02 0.255 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 0.946 0.891 – 1 0.0685 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.02 1.01 – 1.04 0.0072 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.02 1 – 1.04 0.0206 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 1.04 0.855 – 1.26 0.71 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.01 0.992 – 1.03 0.228 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 1.05 1 – 1.1 0.0346 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.999 0.966 – 1.03 0.937 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 1.02 0.968 – 1.07 0.52 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.916 0.781 – 1.07 0.281 159 1587 all phecode
626.8 Infertility, female Genitourinary 1.01 0.953 – 1.07 0.786 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.02 1 – 1.04 0.0425 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 1.02 1 – 1.05 0.0318 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 0.921 0.791 – 1.07 0.294 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1 0.943 – 1.06 0.961 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 1.04 0.923 – 1.16 0.551 310 3097 all phecode
628 Ovarian cyst Genitourinary 1.03 0.995 – 1.06 0.0976 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.03 0.997 – 1.06 0.0778 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.02 0.961 – 1.08 0.502 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.979 0.875 – 1.09 0.709 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.02 0.972 – 1.07 0.453 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.995 0.929 – 1.07 0.892 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.04 0.977 – 1.1 0.237 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.02 0.979 – 1.07 0.319 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 1.08 0.992 – 1.17 0.0772 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.03 0.972 – 1.1 0.283 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 0.976 0.765 – 1.24 0.844 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.05 0.984 – 1.11 0.151 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.02 0.911 – 1.15 0.697 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.03 0.895 – 1.18 0.71 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.03 0.879 – 1.21 0.694 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.968 0.914 – 1.03 0.275 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.99 0.948 – 1.03 0.668 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.1 0.85 – 1.41 0.481 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.938 0.83 – 1.06 0.3 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.04 0.859 – 1.27 0.67 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.07 0.927 – 1.24 0.356 193 1922 all phecode
650 Normal delivery Pregnancy Complications 0.997 0.951 – 1.05 0.906 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 1.05 0.941 – 1.17 0.372 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1.01 0.957 – 1.06 0.828 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.02 0.965 – 1.08 0.498 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.13 0.892 – 1.44 0.306 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.992 0.96 – 1.02 0.611 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.06 0.877 – 1.29 0.53 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 1 0.959 – 1.05 0.945 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.943 0.863 – 1.03 0.198 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 1 0.973 – 1.03 0.89 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.01 0.971 – 1.05 0.581 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.89 0.761 – 1.04 0.142 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.973 0.856 – 1.11 0.674 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.958 0.746 – 1.23 0.74 63 624 all phecode
679 Complications of in utero procedures Dermatologic 0.947 0.725 – 1.24 0.689 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.01 0.986 – 1.03 0.433 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.08 0.991 – 1.18 0.0777 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.04 0.955 – 1.14 0.35 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.987 0.96 – 1.01 0.357 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.989 0.962 – 1.02 0.446 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.989 0.962 – 1.02 0.454 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.17 1.08 – 1.27 0.000251 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.07 1.01 – 1.13 0.0201 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.03 0.989 – 1.08 0.139 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 0.985 0.903 – 1.07 0.73 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 1 0.901 – 1.12 0.966 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1.02 0.935 – 1.12 0.64 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.05 1.01 – 1.1 0.028 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 0.95 0.841 – 1.07 0.415 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 1.17 0.954 – 1.42 0.135 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 0.939 0.903 – 0.975 0.00126 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.993 0.966 – 1.02 0.61 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 1.01 0.794 – 1.29 0.921 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 1.01 0.761 – 1.34 0.949 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 1.16 0.963 – 1.41 0.116 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 1.04 0.972 – 1.11 0.261 986 9854 all phecode
694.1 Vitiligo Dermatologic 1.17 0.907 – 1.51 0.225 60 599 all phecode
694.2 Other dyschromia Dermatologic 1.04 0.968 – 1.12 0.272 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 0.899 0.742 – 1.09 0.276 117 1170 all phecode
695 Erythematous conditions Dermatologic 0.995 0.955 – 1.04 0.823 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 1.05 0.86 – 1.27 0.65 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 0.991 0.835 – 1.17 0.914 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 0.981 0.759 – 1.27 0.884 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.959 0.762 – 1.21 0.725 73 727 all phecode
695.3 Rosacea Dermatologic 1.1 0.979 – 1.23 0.111 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.07 0.967 – 1.18 0.193 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.04 0.876 – 1.24 0.637 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.02 0.917 – 1.14 0.681 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 0.925 0.86 – 0.994 0.0337 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 1.06 0.926 – 1.21 0.416 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 1.12 0.889 – 1.41 0.337 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 0.977 0.889 – 1.07 0.628 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 1 0.958 – 1.05 0.969 2252 22509 all phecode
696.4 Psoriasis Dermatologic 1.01 0.962 – 1.05 0.812 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.02 0.973 – 1.08 0.367 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 0.965 0.894 – 1.04 0.37 706 7052 all phecode
697 Sarcoidosis Dermatologic 0.987 0.905 – 1.08 0.76 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 1.08 1 – 1.16 0.0388 782 7814 all phecode
700 Corns and callosities Dermatologic 0.92 0.815 – 1.04 0.178 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.07 1.04 – 1.1 1.5e-05 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 1.24 0.995 – 1.55 0.0552 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.09 1.05 – 1.14 3.34e-05 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.01 0.783 – 1.3 0.937 61 610 all phecode
701.4 Keloid scar Dermatologic 1.14 0.99 – 1.3 0.0696 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 0.961 0.872 – 1.06 0.412 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.02 0.833 – 1.26 0.82 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.01 0.978 – 1.03 0.688 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 0.985 0.946 – 1.03 0.474 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 1.02 0.983 – 1.06 0.284 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 1.04 0.935 – 1.17 0.441 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 1.05 0.979 – 1.12 0.182 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 1.01 0.986 – 1.04 0.327 5267 52727 all phecode
704.1 Alopecia Dermatologic 1.01 0.838 – 1.21 0.951 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.885 0.693 – 1.13 0.325 76 759 all phecode
705 Disorders of sweat glands Dermatologic 1.03 0.897 – 1.18 0.688 228 2287 all phecode
705.3 Hidradenitis Dermatologic 1.01 0.867 – 1.17 0.933 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 1.04 0.959 – 1.14 0.32 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 1.02 0.993 – 1.04 0.179 8317 83195 all phecode
706.1 Acne Dermatologic 1.22 0.965 – 1.54 0.0967 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 1.01 0.991 – 1.04 0.255 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 0.982 0.937 – 1.03 0.446 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 0.999 0.933 – 1.07 0.979 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.944 0.911 – 0.978 0.0014 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 0.875 0.797 – 0.961 0.00525 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 0.944 0.809 – 1.1 0.464 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.978 0.766 – 1.25 0.86 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.952 0.915 – 0.991 0.0151 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.975 0.896 – 1.06 0.556 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 0.998 0.915 – 1.09 0.972 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.11 0.962 – 1.29 0.15 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.918 0.828 – 1.02 0.105 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 0.946 0.856 – 1.05 0.276 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 0.929 0.829 – 1.04 0.202 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.1 0.878 – 1.37 0.413 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.972 0.823 – 1.15 0.741 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.11 0.86 – 1.42 0.434 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.01 0.978 – 1.04 0.642 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.01 0.979 – 1.04 0.544 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.05 0.999 – 1.1 0.0531 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.972 0.802 – 1.18 0.769 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.02 0.939 – 1.11 0.634 618 6177 all phecode
716 Other arthropathies Musculoskeletal 0.996 0.986 – 1.01 0.513 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.01 0.971 – 1.04 0.763 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.986 0.97 – 1 0.0943 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 0.995 0.984 – 1.01 0.4 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1 0.942 – 1.06 0.993 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 1 0.968 – 1.04 0.959 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1.02 0.998 – 1.05 0.0777 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.01 0.978 – 1.04 0.654 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.05 0.906 – 1.22 0.519 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.01 0.908 – 1.13 0.817 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 1.02 0.999 – 1.04 0.0653 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.01 0.924 – 1.11 0.803 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.01 0.968 – 1.05 0.757 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.13 0.869 – 1.46 0.372 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.03 0.994 – 1.06 0.11 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 1.03 0.94 – 1.13 0.54 517 5173 all phecode
723.1 Torticollis Musculoskeletal 1.15 0.939 – 1.4 0.181 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.01 0.962 – 1.05 0.795 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 0.988 0.892 – 1.09 0.818 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 1 0.904 – 1.11 0.979 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 0.924 0.719 – 1.19 0.541 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1 0.954 – 1.06 0.873 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.995 0.979 – 1.01 0.592 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 0.996 0.976 – 1.02 0.742 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 1.04 0.927 – 1.16 0.54 334 3336 all phecode
726.3 Bursitis Musculoskeletal 1.04 0.968 – 1.12 0.286 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.994 0.97 – 1.02 0.616 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.985 0.947 – 1.02 0.448 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 0.829 0.678 – 1.01 0.0661 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.983 0.948 – 1.02 0.369 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 0.974 0.894 – 1.06 0.544 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.998 0.895 – 1.11 0.978 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.13 0.954 – 1.34 0.157 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1 0.97 – 1.04 0.868 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.05 0.951 – 1.16 0.325 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 1 0.969 – 1.04 0.902 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1 0.968 – 1.04 0.893 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.01 0.987 – 1.04 0.313 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.02 0.956 – 1.09 0.538 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 0.931 0.763 – 1.13 0.479 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.07 0.942 – 1.21 0.31 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.07 0.941 – 1.21 0.306 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 1 0.914 – 1.1 0.935 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.04 0.903 – 1.2 0.58 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.01 0.773 – 1.32 0.941 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.05 1 – 1.11 0.0378 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 1.24 1.11 – 1.39 0.000186 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.946 0.866 – 1.03 0.219 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 0.929 0.775 – 1.11 0.424 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1 0.946 – 1.06 0.922 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 0.95 0.787 – 1.15 0.593 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 0.987 0.967 – 1.01 0.228 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 1.02 0.871 – 1.18 0.84 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 0.999 0.971 – 1.03 0.947 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.993 0.947 – 1.04 0.757 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 1 0.949 – 1.05 0.994 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.978 0.954 – 1 0.0888 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 1.05 0.995 – 1.1 0.076 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 0.991 0.87 – 1.13 0.898 248 2476 all phecode
737 Curvature of spine Musculoskeletal 0.99 0.931 – 1.05 0.748 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.986 0.926 – 1.05 0.658 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.992 0.946 – 1.04 0.745 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.01 0.96 – 1.07 0.667 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 1.05 0.958 – 1.15 0.299 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 0.996 0.983 – 1.01 0.505 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.982 0.967 – 0.998 0.0249 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.969 0.948 – 0.99 0.00459 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.989 0.886 – 1.1 0.845 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.919 0.845 – 1 0.049 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.01 0.99 – 1.03 0.376 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.97 0.937 – 1 0.0823 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 1.04 0.849 – 1.28 0.684 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 1.03 0.951 – 1.12 0.449 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 0.984 0.835 – 1.16 0.843 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 0.942 0.892 – 0.995 0.0324 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 0.964 0.798 – 1.17 0.707 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 0.955 0.727 – 1.25 0.741 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.984 0.947 – 1.02 0.424 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 0.992 0.886 – 1.11 0.886 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.04 0.841 – 1.28 0.74 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 0.981 0.895 – 1.08 0.688 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 0.987 0.943 – 1.03 0.589 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.01 0.985 – 1.03 0.465 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 1.01 0.981 – 1.03 0.63 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 1.01 0.982 – 1.04 0.503 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1.01 0.925 – 1.11 0.801 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 1.01 0.92 – 1.1 0.87 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.04 0.972 – 1.12 0.235 815 8144 all phecode
745 Pain in joint Musculoskeletal 1.01 0.986 – 1.03 0.465 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.978 0.941 – 1.02 0.27 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.981 0.943 – 1.02 0.357 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1.05 0.962 – 1.14 0.292 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.961 0.839 – 1.1 0.571 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.971 0.925 – 1.02 0.239 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.999 0.853 – 1.17 0.986 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.08 0.819 – 1.41 0.602 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.997 0.887 – 1.12 0.961 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 1.03 0.955 – 1.12 0.422 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.02 0.912 – 1.14 0.716 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.07 0.925 – 1.24 0.357 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.07 0.96 – 1.19 0.225 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.12 0.977 – 1.27 0.106 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.932 0.768 – 1.13 0.474 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.995 0.944 – 1.05 0.853 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.954 0.882 – 1.03 0.243 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.944 0.857 – 1.04 0.241 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.986 0.857 – 1.14 0.849 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.01 0.943 – 1.09 0.719 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 1.01 0.917 – 1.12 0.787 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1 0.894 – 1.12 0.978 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.984 0.882 – 1.1 0.775 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 0.955 0.842 – 1.08 0.469 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 0.969 0.843 – 1.11 0.66 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.05 0.838 – 1.32 0.671 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.931 0.775 – 1.12 0.445 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.929 0.736 – 1.17 0.537 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1 0.833 – 1.21 0.974 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.02 0.921 – 1.12 0.738 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.1 0.952 – 1.27 0.199 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.06 0.903 – 1.24 0.476 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.1 0.907 – 1.34 0.328 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.934 0.859 – 1.02 0.108 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.923 0.737 – 1.16 0.485 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.93 0.844 – 1.02 0.143 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.963 0.813 – 1.14 0.662 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.04 0.805 – 1.34 0.761 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.992 0.863 – 1.14 0.907 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.806 0.654 – 0.992 0.0422 96 959 all phecode
760 Back pain Symptoms 1 0.982 – 1.02 0.877 11126 111353 all phecode
761 Cervicalgia Symptoms 1.02 0.97 – 1.07 0.461 1791 17901 all phecode
764 Sciatica Symptoms 0.999 0.958 – 1.04 0.957 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.04 0.975 – 1.1 0.255 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 1.02 0.941 – 1.11 0.628 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.963 0.899 – 1.03 0.293 870 8687 all phecode
771.1 Swelling of limb Symptoms 1.02 0.988 – 1.05 0.236 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 0.953 0.88 – 1.03 0.237 659 6581 all phecode
773 Pain in limb Symptoms 1.01 0.988 – 1.04 0.303 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 1.03 0.887 – 1.21 0.664 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.01 0.967 – 1.06 0.588 1870 18715 all phecode
782.3 Edema Symptoms 1.07 1.01 – 1.12 0.0133 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 0.983 0.844 – 1.15 0.831 175 1748 all phecode
783 Fever of unknown origin Symptoms 1.06 1.03 – 1.1 0.00032 3911 39105 all phecode
785 Abdominal pain Symptoms 1.01 0.995 – 1.02 0.272 40080 301686 all phecode
788 Syncope and collapse Symptoms 0.995 0.974 – 1.02 0.667 9069 90813 all phecode
789 Nausea and vomiting Symptoms 1.02 0.997 – 1.04 0.0974 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.07 0.906 – 1.27 0.424 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 1.14 0.909 – 1.42 0.261 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 1 0.978 – 1.03 0.762 6357 63635 all phecode
791 Gangrene Symptoms 0.897 0.821 – 0.98 0.0161 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1.07 0.867 – 1.31 0.541 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.01 0.851 – 1.2 0.902 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 0.986 0.904 – 1.08 0.758 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.06 0.879 – 1.28 0.533 120 1198 all phecode
797 Shock Symptoms 1.03 0.868 – 1.21 0.769 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 1.1 0.899 – 1.34 0.36 102 1020 all phecode
798 Malaise and fatigue Symptoms 1.02 0.98 – 1.05 0.39 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 1.03 0.943 – 1.12 0.536 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 1.01 0.986 – 1.04 0.417 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.01 0.967 – 1.07 0.55 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.978 0.834 – 1.15 0.782 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.992 0.949 – 1.04 0.715 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 1.03 0.953 – 1.11 0.484 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.01 0.965 – 1.05 0.725 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.03 0.978 – 1.08 0.29 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.967 0.896 – 1.04 0.386 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.989 0.967 – 1.01 0.351 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 0.99 0.942 – 1.04 0.702 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.979 0.952 – 1.01 0.145 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.02 0.965 – 1.07 0.532 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.997 0.962 – 1.03 0.856 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.998 0.944 – 1.06 0.94 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 1.02 0.95 – 1.1 0.528 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.964 0.91 – 1.02 0.206 1300 12998 all phecode
817 Concussion Injuries & Poisonings 0.9 0.788 – 1.03 0.12 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.09 0.994 – 1.19 0.068 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.01 0.969 – 1.05 0.751 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 0.999 0.95 – 1.05 0.967 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 1.02 0.971 – 1.06 0.494 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 0.989 0.973 – 1.01 0.197 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.01 0.928 – 1.11 0.758 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 0.99 0.9 – 1.09 0.846 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.06 1.03 – 1.09 4.92e-05 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.12 0.947 – 1.33 0.185 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 0.988 0.9 – 1.08 0.796 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.02 0.971 – 1.07 0.455 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.03 0.975 – 1.1 0.262 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.925 0.892 – 0.96 3.16e-05 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.04 1.01 – 1.08 0.0213 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1.02 0.795 – 1.31 0.877 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1 0.967 – 1.04 0.949 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.961 0.848 – 1.09 0.531 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.949 0.822 – 1.1 0.48 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.03 0.989 – 1.07 0.161 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.01 0.879 – 1.16 0.904 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 0.963 0.751 – 1.23 0.764 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 0.986 0.955 – 1.02 0.385 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1 0.756 – 1.32 0.998 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.948 0.761 – 1.18 0.63 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.874 0.75 – 1.02 0.082 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 0.949 0.862 – 1.04 0.283 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 1.17 1.03 – 1.34 0.0204 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.09 0.932 – 1.27 0.279 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.08 0.92 – 1.26 0.354 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.04 0.978 – 1.1 0.228 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.01 0.983 – 1.05 0.376 4260 42663 all phecode
916 Contusion Injuries & Poisonings 1 0.948 – 1.06 0.986 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.961 0.826 – 1.12 0.605 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.975 0.881 – 1.08 0.631 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.963 0.849 – 1.09 0.554 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.983 0.94 – 1.03 0.446 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.1 0.956 – 1.26 0.186 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.02 0.834 – 1.24 0.863 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.15 1.05 – 1.25 0.00259 550 5509 all phecode
947 Urticaria Injuries & Poisonings 1.02 0.916 – 1.13 0.727 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 1.07 0.96 – 1.18 0.233 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.938 0.848 – 1.04 0.215 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.07 0.939 – 1.21 0.322 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.908 0.827 – 0.997 0.0434 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.13 0.848 – 1.5 0.407 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.895 0.704 – 1.14 0.365 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.02 1.01 – 1.04 0.00743 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.02 1 – 1.04 0.0198 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.04 0.945 – 1.15 0.395 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.09 1.01 – 1.16 0.0222 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.05 0.943 – 1.16 0.386 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.947 – 1.17 0.338 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.13 0.985 – 1.29 0.0817 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1 0.887 – 1.13 0.999 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.04 0.917 – 1.17 0.578 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1 0.974 – 1.03 0.976 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.03 0.967 – 1.09 0.386 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.993 0.904 – 1.09 0.884 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.979 0.884 – 1.08 0.688 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.94 0.86 – 1.03 0.176 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.946 0.869 – 1.03 0.2 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.05 1.01 – 1.1 0.0248 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.985 0.848 – 1.14 0.844 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.952 0.842 – 1.08 0.437 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.04 0.832 – 1.29 0.746 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 0.984 0.813 – 1.19 0.871 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.03 0.844 – 1.26 0.767 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.17 0.912 – 1.5 0.218 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.03 0.785 – 1.34 0.842 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.12 0.977 – 1.27 0.107 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.06 0.981 – 1.14 0.14 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.08 0.936 – 1.25 0.289 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.08 0.834 – 1.41 0.55 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.08 0.89 – 1.31 0.439 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 1.03 0.841 – 1.25 0.8 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.11 0.896 – 1.37 0.345 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.15 1.11 – 1.2 1.58e-14 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.05 1.01 – 1.09 0.017 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 1.05 1.01 – 1.09 0.017 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 0.994 0.972 – 1.02 0.63 8379 85301 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1 0.961 – 1.04 0.979 2590 26211 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.1 1.01 – 1.19 0.0325 601 6297 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.03 0.958 – 1.11 0.428 811 8331 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.03 0.782 – 1.35 0.846 54 542 exclusion phecode
010 Tuberculosis Infectious Diseases 1.17 0.993 – 1.37 0.0612 158 1619 exclusion phecode
038 Septicemia Infectious Diseases 0.978 0.946 – 1.01 0.203 3636 40570 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 0.96 0.894 – 1.03 0.266 806 8283 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 0.932 0.849 – 1.02 0.141 469 4877 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 0.994 0.975 – 1.01 0.549 11325 116648 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 0.992 0.955 – 1.03 0.688 2860 30495 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 0.985 0.936 – 1.04 0.569 1576 16002 exclusion phecode
041.4 E. coli Infectious Diseases 0.994 0.955 – 1.04 0.781 2565 26190 exclusion phecode
053 Herpes zoster Infectious Diseases 1.09 0.978 – 1.21 0.124 388 3985 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.07 0.866 – 1.33 0.518 91 914 exclusion phecode
054 Herpes simplex Infectious Diseases 0.996 0.862 – 1.15 0.957 195 2043 exclusion phecode
070 Viral hepatitis Infectious Diseases 0.984 0.904 – 1.07 0.709 575 5772 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.03 0.8 – 1.32 0.834 64 665 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.938 0.786 – 1.12 0.481 129 1306 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 0.993 0.873 – 1.13 0.913 252 2515 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.01 0.888 – 1.15 0.85 263 2639 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 0.979 0.885 – 1.08 0.682 411 4155 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.07 0.905 – 1.26 0.436 147 1465 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.05 0.869 – 1.26 0.631 117 1168 exclusion phecode
078 Viral warts & HPV Infectious Diseases 1.02 0.958 – 1.09 0.483 964 9684 exclusion phecode
079 Viral infection Infectious Diseases 1.01 0.972 – 1.05 0.572 2646 26769 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.835 0.647 – 1.08 0.165 62 621 exclusion phecode
080 Postoperative infection Infectious Diseases 0.964 0.933 – 0.996 0.0279 4013 43412 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 0.98 0.939 – 1.02 0.35 2238 24034 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.02 0.813 – 1.28 0.856 67 692 exclusion phecode
1000 Burns Injuries & Poisonings 1.01 0.925 – 1.1 0.848 565 5660 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 0.961 0.905 – 1.02 0.192 1164 11686 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.01 0.979 – 1.04 0.609 5240 52778 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.08 0.952 – 1.21 0.241 292 2920 exclusion phecode
1005 Other symptoms Injuries & Poisonings 0.989 0.935 – 1.05 0.693 1318 13963 exclusion phecode
1006 Crushing injury Injuries & Poisonings 0.895 0.786 – 1.02 0.0933 256 2525 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 1.02 0.9 – 1.16 0.733 252 2521 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.01 0.95 – 1.08 0.694 993 9977 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 0.992 0.97 – 1.01 0.5 8273 82852 exclusion phecode
1010 Other tests Injuries & Poisonings 0.976 0.95 – 1 0.087 5636 57417 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.975 0.954 – 0.997 0.0272 8521 88559 exclusion phecode
1012 Late effect Injuries & Poisonings 0.913 0.745 – 1.12 0.381 103 1023 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.04 0.927 – 1.17 0.495 300 3081 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.965 0.748 – 1.25 0.786 66 649 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 0.99 0.958 – 1.02 0.557 3947 40919 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.02 1 – 1.04 0.0354 15111 153823 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.04 0.917 – 1.17 0.573 274 2751 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 1.04 0.921 – 1.18 0.515 268 2689 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.871 0.688 – 1.1 0.25 73 736 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.08 0.91 – 1.29 0.369 139 1386 exclusion phecode
112 Candidiasis Infectious Diseases 0.942 0.898 – 0.987 0.0121 1944 20482 exclusion phecode
117 Mycoses Infectious Diseases 1.03 0.905 – 1.16 0.685 255 2636 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1 0.852 – 1.17 0.998 155 1600 exclusion phecode
130 Spirochetal infection Infectious Diseases 1.22 0.965 – 1.53 0.0969 78 787 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 0.902 0.707 – 1.15 0.404 69 667 exclusion phecode
134 Helminthiases Infectious Diseases 1.16 0.96 – 1.4 0.126 122 1218 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.12 0.916 – 1.38 0.263 101 1019 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.13 0.977 – 1.3 0.101 197 1983 exclusion phecode
145 Cancer of mouth Neoplasms 0.983 0.905 – 1.07 0.675 612 6264 exclusion phecode
145.2 Cancer of tongue Neoplasms 0.952 0.848 – 1.07 0.402 299 3043 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.967 0.788 – 1.18 0.744 100 1016 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.28 0.962 – 1.69 0.0901 51 531 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.01 0.933 – 1.1 0.758 618 6235 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 0.967 0.848 – 1.1 0.622 246 2476 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.04 0.915 – 1.18 0.565 263 2610 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.1 0.817 – 1.47 0.539 51 549 exclusion phecode
150 Cancer of esophagus Neoplasms 1.03 0.951 – 1.1 0.518 731 7507 exclusion phecode
151 Cancer of stomach Neoplasms 0.987 0.905 – 1.08 0.776 546 5582 exclusion phecode
153 Colorectal cancer Neoplasms 1 0.973 – 1.03 0.831 4395 44434 exclusion phecode
153.2 Colon cancer Neoplasms 0.992 0.955 – 1.03 0.678 2968 30114 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.02 0.973 – 1.06 0.452 2082 21023 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.965 0.871 – 1.07 0.499 390 3880 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.894 0.759 – 1.05 0.184 155 1545 exclusion phecode
157 Pancreatic cancer Neoplasms 0.984 0.907 – 1.07 0.706 634 6387 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.06 0.996 – 1.13 0.0648 1014 10297 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.01 0.981 – 1.04 0.518 5260 53904 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.958 0.829 – 1.11 0.565 181 1851 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.974 0.84 – 1.13 0.726 196 1964 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.02 0.875 – 1.18 0.843 183 1825 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 1.11 0.848 – 1.45 0.453 53 582 exclusion phecode
165 Cancer within the respiratory system Neoplasms 0.989 0.951 – 1.03 0.602 2621 27408 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 0.995 0.951 – 1.04 0.829 2065 21597 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 0.971 0.876 – 1.08 0.567 399 4223 exclusion phecode
170.1 Bone cancer Neoplasms 1.04 0.862 – 1.25 0.69 121 1271 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 0.97 0.863 – 1.09 0.611 301 3194 exclusion phecode
172 Skin cancer Neoplasms 1.01 0.988 – 1.02 0.496 12923 130528 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.04 1 – 1.09 0.0393 2570 25813 exclusion phecode
172.11 Melanomas of skin Neoplasms 1.05 1 – 1.09 0.0281 2599 26116 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.998 0.978 – 1.02 0.856 10529 106496 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.963 0.887 – 1.05 0.37 634 6438 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.02 0.877 – 1.19 0.789 173 1759 exclusion phecode
175 Acquired absence of breast Neoplasms 1.29 1.01 – 1.64 0.0386 63 24010 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.02 0.973 – 1.06 0.451 2050 21747 exclusion phecode
180.1 Cervical cancer Neoplasms 1.03 0.905 – 1.16 0.684 251 2720 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1 0.957 – 1.05 0.93 1960 20784 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 1.08 1.01 – 1.14 0.0201 1123 12836 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.05 0.993 – 1.11 0.0839 1256 13772 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.08 1 – 1.15 0.0398 868 9667 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.07 0.995 – 1.14 0.0684 842 9387 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.998 0.885 – 1.13 0.972 286 3049 exclusion phecode
185 Cancer of prostate Neoplasms 1.04 1.01 – 1.07 0.00474 5954 58768 exclusion phecode
187 Cancer of other male genital organs Neoplasms 1.05 0.953 – 1.16 0.325 448 4485 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.04 0.82 – 1.33 0.731 70 699 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 1.03 0.91 – 1.16 0.675 287 2868 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.07 0.875 – 1.3 0.519 109 1098 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.982 0.95 – 1.01 0.262 4020 40759 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.04 0.978 – 1.11 0.198 1034 10461 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.03 0.967 – 1.1 0.331 996 10080 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.25 0.961 – 1.61 0.0966 63 646 exclusion phecode
189.2 Cancer of bladder Neoplasms 0.953 0.913 – 0.994 0.0264 2339 23695 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.955 0.913 – 1 0.0479 2076 21095 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.988 0.834 – 1.17 0.887 140 1419 exclusion phecode
190 Cancer of eye Neoplasms 1.11 0.947 – 1.3 0.195 169 1707 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.01 0.933 – 1.1 0.798 658 6688 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.973 0.891 – 1.06 0.543 542 5503 exclusion phecode
191.11 Cancer of brain Neoplasms 0.992 0.905 – 1.09 0.864 504 5095 exclusion phecode
193 Thyroid cancer Neoplasms 0.978 0.873 – 1.09 0.692 318 3327 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 0.873 0.701 – 1.09 0.222 88 921 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.03 1.01 – 1.04 0.00127 15439 162081 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.03 1.01 – 1.05 0.00146 14863 156272 exclusion phecode
197 Chemotherapy Neoplasms 1.01 0.994 – 1.02 0.258 17657 207907 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1 0.979 – 1.03 0.762 6667 93092 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.989 0.954 – 1.03 0.568 3078 52189 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.978 0.931 – 1.03 0.367 1777 22192 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.02 0.966 – 1.08 0.461 1354 15054 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 0.995 0.953 – 1.04 0.833 2186 26106 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.949 0.874 – 1.03 0.204 641 8296 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.04 0.986 – 1.09 0.152 1547 21152 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.977 0.831 – 1.15 0.781 149 1849 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 0.999 0.945 – 1.06 0.986 1321 14033 exclusion phecode
199.4 Neurofibromatosis Neoplasms 0.985 0.793 – 1.22 0.892 89 926 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.05 0.984 – 1.12 0.14 961 9626 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.02 0.917 – 1.14 0.715 376 3804 exclusion phecode
201 Hodgkin's disease Neoplasms 1.04 0.911 – 1.18 0.588 250 2530 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.03 0.989 – 1.08 0.143 2162 22008 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.04 0.989 – 1.09 0.127 1743 17502 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.06 0.952 – 1.19 0.28 354 3530 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.03 0.945 – 1.12 0.513 566 5631 exclusion phecode
204 Leukemia Neoplasms 1.01 0.962 – 1.07 0.633 1597 16180 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 0.974 0.894 – 1.06 0.556 555 5648 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.08 0.828 – 1.42 0.557 52 549 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.986 0.899 – 1.08 0.757 489 4957 exclusion phecode
204.2 Myeloid leukemia Neoplasms 0.993 0.902 – 1.09 0.883 444 4485 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.935 0.834 – 1.05 0.253 316 3196 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.11 0.931 – 1.33 0.238 139 1394 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.07 0.98 – 1.17 0.128 539 5406 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1.01 0.996 – 1.03 0.148 19228 186240 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.998 0.933 – 1.07 0.945 936 9450 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1 0.971 – 1.03 0.997 5006 50361 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.08 0.966 – 1.21 0.177 338 3385 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.02 0.902 – 1.14 0.796 300 3096 exclusion phecode
214 Lipoma Neoplasms 1.01 0.983 – 1.04 0.466 5986 60612 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.01 0.983 – 1.05 0.372 4386 44453 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.972 0.913 – 1.03 0.373 1046 10650 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.984 0.96 – 1.01 0.18 7309 73983 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.07 0.983 – 1.16 0.121 602 6107 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 1.08 0.99 – 1.18 0.0849 566 5742 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 1.04 1.01 – 1.06 0.001 9300 94888 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 1.04 1.02 – 1.06 0.00036 9500 96859 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.99 0.883 – 1.11 0.858 327 3355 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 1 0.95 – 1.06 0.871 1338 14483 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.04 0.897 – 1.2 0.616 198 2196 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 1.03 0.872 – 1.21 0.738 159 1600 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.982 0.84 – 1.15 0.822 166 1683 exclusion phecode
224 Benign neoplasm of eye Neoplasms 1.24 1.03 – 1.48 0.0242 124 1249 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.26 0.994 – 1.61 0.0561 65 656 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.15 1.07 – 1.23 0.000255 778 7835 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.16 1.07 – 1.25 0.000154 739 7446 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.943 0.714 – 1.24 0.677 56 563 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.08 0.95 – 1.23 0.238 249 2522 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.968 0.901 – 1.04 0.374 818 8332 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.925 0.795 – 1.08 0.319 179 1810 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.98 0.878 – 1.09 0.724 343 3542 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.976 0.867 – 1.1 0.689 301 3042 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.99 0.94 – 1.04 0.72 1537 15454 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.978 0.937 – 1.02 0.322 2266 22955 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.08 0.986 – 1.17 0.0997 554 5720 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.98 0.92 – 1.04 0.536 1033 10551 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.983 0.893 – 1.08 0.721 442 4497 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.979 0.902 – 1.06 0.602 630 6447 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.965 0.918 – 1.01 0.165 1705 17654 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.936 0.848 – 1.03 0.188 424 4357 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.04 0.831 – 1.31 0.712 83 865 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.887 0.743 – 1.06 0.183 129 1312 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 0.982 0.965 – 1 0.0489 13520 137647 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.958 0.897 – 1.02 0.197 987 10500 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.915 0.746 – 1.12 0.393 98 953 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.982 0.965 – 1 0.0536 12915 131813 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.958 0.845 – 1.09 0.501 273 2708 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.999 0.866 – 1.15 0.993 208 2042 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.986 0.853 – 1.14 0.852 202 1962 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 0.948 0.852 – 1.05 0.325 365 3773 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 0.99 0.976 – 1.01 0.198 19064 181091 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.991 0.952 – 1.03 0.644 2665 26910 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.934 0.816 – 1.07 0.323 228 2327 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.948 0.748 – 1.2 0.66 72 756 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.01 0.912 – 1.11 0.919 455 4628 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.02 0.869 – 1.2 0.781 153 1581 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.992 0.977 – 1.01 0.338 17165 165745 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.741 0.605 – 0.908 0.00382 99 1025 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.97 0.837 – 1.12 0.683 198 1974 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.932 0.871 – 0.996 0.0373 967 9690 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.03 0.94 – 1.13 0.522 490 4956 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 0.972 0.897 – 1.05 0.492 654 6651 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.93 0.818 – 1.06 0.268 257 2600 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.01 0.913 – 1.12 0.81 399 4066 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.02 0.855 – 1.23 0.8 128 1271 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.07 0.961 – 1.2 0.208 342 3436 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.961 0.907 – 1.02 0.17 1298 13037 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 0.957 0.895 – 1.02 0.204 907 9125 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.971 0.904 – 1.04 0.426 812 8327 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.975 0.904 – 1.05 0.515 727 7455 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1 0.843 – 1.2 0.957 134 1361 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.06 0.975 – 1.14 0.183 656 6614 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.05 0.897 – 1.22 0.567 179 1802 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.06 0.85 – 1.33 0.597 90 908 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.03 0.91 – 1.17 0.61 255 2563 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.09 0.867 – 1.36 0.476 88 887 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.07 0.906 – 1.26 0.424 151 1519 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.05 0.97 – 1.14 0.221 615 6134 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.22 1.05 – 1.41 0.0112 173 1726 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.11 0.913 – 1.36 0.287 98 980 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.29 1.03 – 1.62 0.0276 74 742 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.995 0.89 – 1.11 0.926 351 3479 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.994 0.89 – 1.11 0.92 350 3469 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 1.03 0.895 – 1.18 0.708 230 2316 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.04 0.896 – 1.2 0.617 201 2023 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1.09 0.929 – 1.28 0.292 159 1619 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.08 0.917 – 1.27 0.365 151 1538 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.05 0.853 – 1.3 0.624 101 984 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.95 0.803 – 1.12 0.55 139 1442 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.05 0.91 – 1.21 0.495 192 1960 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.01 0.935 – 1.08 0.881 800 8034 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 0.982 0.924 – 1.04 0.565 1147 11490 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.977 0.905 – 1.05 0.549 728 7267 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.963 0.872 – 1.06 0.458 420 4257 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.08 0.855 – 1.37 0.505 72 728 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.973 0.847 – 1.12 0.693 224 2303 exclusion phecode
269 Proteinuria Endocrine/metabolic 0.971 0.868 – 1.09 0.612 330 3297 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.999 0.888 – 1.12 0.992 294 2934 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.97 0.853 – 1.1 0.641 252 2518 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.04 0.892 – 1.21 0.638 184 1844 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1.03 0.841 – 1.25 0.8 107 1093 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.854 0.667 – 1.09 0.21 67 667 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.09 0.925 – 1.28 0.312 153 1545 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.1 0.927 – 1.32 0.265 132 1339 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.993 0.982 – 1 0.264 33648 227899 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.993 0.982 – 1 0.243 33579 227676 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.994 0.983 – 1.01 0.365 31216 220787 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.08 0.829 – 1.4 0.573 58 570 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.88 0.751 – 1.03 0.117 163 1597 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.963 0.834 – 1.11 0.611 207 2042 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.976 0.944 – 1.01 0.161 3673 36757 exclusion phecode
274.1 Gout Endocrine/metabolic 0.976 0.941 – 1.01 0.194 3137 31394 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.04 0.856 – 1.27 0.685 110 1110 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.992 0.912 – 1.08 0.848 596 5956 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.987 0.904 – 1.08 0.774 543 5425 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.01 0.963 – 1.06 0.726 1956 20480 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 1.07 0.983 – 1.16 0.121 641 6412 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.02 0.915 – 1.14 0.686 350 3620 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.958 0.9 – 1.02 0.176 1079 11629 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.89 0.759 – 1.04 0.152 164 1688 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.01 0.982 – 1.03 0.609 6859 70648 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1 0.97 – 1.04 0.864 3862 39623 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.06 0.93 – 1.22 0.365 233 2344 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 0.985 0.937 – 1.04 0.558 1712 17550 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.03 0.963 – 1.1 0.396 923 9507 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 0.997 0.942 – 1.06 0.921 1338 13705 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.987 0.928 – 1.05 0.67 1109 11326 exclusion phecode
276.41 Acidosis Endocrine/metabolic 0.976 0.915 – 1.04 0.469 1008 10309 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1 0.826 – 1.21 0.996 109 1093 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.01 0.973 – 1.05 0.549 2627 27375 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1 0.909 – 1.11 0.962 433 4415 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 0.973 0.808 – 1.17 0.77 124 1234 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 0.992 0.924 – 1.06 0.813 847 8677 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1 0.9 – 1.12 0.968 350 3555 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.06 0.923 – 1.21 0.428 226 2240 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.07 0.805 – 1.42 0.646 51 509 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.988 0.968 – 1.01 0.246 10280 104821 exclusion phecode
278.1 Obesity Endocrine/metabolic 0.988 0.968 – 1.01 0.265 10127 103273 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 0.955 0.755 – 1.21 0.702 75 804 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.853 0.66 – 1.1 0.226 65 634 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.95 0.831 – 1.08 0.446 239 2427 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 0.927 0.8 – 1.07 0.316 203 2032 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.979 0.816 – 1.17 0.822 134 1331 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.09 0.953 – 1.24 0.214 244 2455 exclusion phecode
280 Iron deficiency anemias Hematopoietic 0.995 0.972 – 1.02 0.71 7300 73421 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.996 0.972 – 1.02 0.76 7021 70520 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.993 0.897 – 1.1 0.885 427 4366 exclusion phecode
281 Other deficiency anemia Hematopoietic 0.959 0.9 – 1.02 0.184 1061 10695 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 0.952 0.893 – 1.01 0.132 1016 10246 exclusion phecode
281.11 Pernicious anemia Hematopoietic 0.958 0.887 – 1.03 0.27 711 7206 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.909 0.774 – 1.07 0.239 170 1710 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 0.957 0.824 – 1.11 0.56 178 1775 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.1 0.843 – 1.44 0.483 51 525 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1 0.845 – 1.19 0.959 141 1459 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.86 0.69 – 1.07 0.181 82 823 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 0.935 0.784 – 1.12 0.457 131 1329 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.963 0.784 – 1.18 0.722 100 1031 exclusion phecode
284 Aplastic anemia Hematopoietic 1 0.907 – 1.11 0.935 411 4245 exclusion phecode
285 Other anemias Hematopoietic 0.988 0.969 – 1.01 0.202 11381 116882 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.853 0.752 – 0.969 0.0142 247 2611 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.04 0.956 – 1.13 0.378 605 6738 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.02 0.917 – 1.14 0.67 333 4002 exclusion phecode
286 Coagulation defects Hematopoietic 1.02 0.948 – 1.09 0.657 870 8954 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 1.08 0.978 – 1.19 0.127 434 4452 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.984 0.798 – 1.21 0.878 88 927 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.04 0.923 – 1.18 0.502 280 2851 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.11 0.848 – 1.45 0.45 59 617 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.18 0.953 – 1.46 0.129 85 843 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.957 0.859 – 1.07 0.421 360 3754 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.999 0.948 – 1.05 0.959 1554 16086 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.16 0.966 – 1.39 0.112 125 1247 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 0.994 0.942 – 1.05 0.828 1458 15123 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 0.968 0.872 – 1.07 0.542 401 4058 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.01 0.797 – 1.28 0.941 71 736 exclusion phecode
288 Diseases of white blood cells Hematopoietic 0.985 0.948 – 1.02 0.428 2801 36328 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 0.98 0.939 – 1.02 0.355 2252 30535 exclusion phecode
288.11 Neutropenia Hematopoietic 0.978 0.937 – 1.02 0.298 2259 30604 exclusion phecode
288.3 Eosinophilia Hematopoietic 1.12 0.873 – 1.44 0.372 68 692 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.04 0.964 – 1.11 0.344 825 8353 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.994 0.879 – 1.12 0.922 275 2799 exclusion phecode
289.4 Lymphadenitis Hematopoietic 0.975 0.935 – 1.02 0.24 2365 25341 exclusion phecode
289.5 Diseases of spleen Hematopoietic 0.97 0.884 – 1.06 0.52 491 4991 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.03 0.915 – 1.17 0.606 286 2877 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.02 0.822 – 1.25 0.889 87 878 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.977 0.931 – 1.03 0.346 1830 18642 exclusion phecode
290.1 Dementias Mental Disorders 0.96 0.898 – 1.03 0.231 952 9666 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.988 0.891 – 1.09 0.813 402 4115 exclusion phecode
290.16 Vascular dementia Mental Disorders 1.13 0.985 – 1.31 0.0808 198 1958 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.03 0.949 – 1.12 0.486 622 6316 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.07 0.84 – 1.36 0.591 69 700 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.01 0.941 – 1.09 0.763 806 8148 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.03 0.862 – 1.23 0.751 128 1283 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.02 0.902 – 1.15 0.751 280 2780 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.01 0.91 – 1.11 0.902 416 4258 exclusion phecode
292 Neurological disorders Mental Disorders 0.994 0.964 – 1.03 0.725 4419 44886 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.971 0.92 – 1.02 0.28 1436 14647 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.967 0.833 – 1.12 0.664 186 1857 exclusion phecode
292.3 Memory loss Mental Disorders 1 0.925 – 1.08 0.988 672 6772 exclusion phecode
292.4 Altered mental status Mental Disorders 0.994 0.95 – 1.04 0.797 2077 21189 exclusion phecode
292.6 Hallucinations Mental Disorders 1.06 0.945 – 1.2 0.305 297 2975 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 0.969 0.926 – 1.01 0.169 2052 20446 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.993 0.926 – 1.07 0.853 853 8740 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.02 0.945 – 1.09 0.667 815 8254 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.02 0.932 – 1.11 0.712 556 5660 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.07 0.913 – 1.24 0.421 169 1732 exclusion phecode
295.3 Psychosis Mental Disorders 0.942 0.802 – 1.1 0.46 167 1664 exclusion phecode
296 Mood disorders Mental Disorders 1.01 0.987 – 1.02 0.563 11748 119692 exclusion phecode
296.1 Bipolar Mental Disorders 1.06 0.991 – 1.13 0.0929 1015 10309 exclusion phecode
296.2 Depression Mental Disorders 1 0.984 – 1.02 0.765 11133 113508 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.07 0.958 – 1.19 0.235 349 3472 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.919 0.814 – 1.04 0.168 299 2966 exclusion phecode
300 Anxiety disorders Mental Disorders 1.01 0.982 – 1.03 0.548 6464 66182 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.01 0.986 – 1.04 0.338 5961 61101 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 1.02 0.856 – 1.21 0.846 143 1453 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1 0.928 – 1.09 0.924 669 6839 exclusion phecode
300.13 Phobia Mental Disorders 0.93 0.846 – 1.02 0.131 464 4821 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.975 0.819 – 1.16 0.781 139 1371 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.12 0.928 – 1.36 0.236 119 1210 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.891 0.738 – 1.08 0.232 113 1101 exclusion phecode
301 Personality disorders Mental Disorders 0.881 0.786 – 0.986 0.0282 321 3254 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.872 0.724 – 1.05 0.146 113 1147 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 0.984 0.871 – 1.11 0.791 283 2836 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.979 0.889 – 1.08 0.665 450 4516 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 1 0.896 – 1.12 0.98 336 3398 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.846 0.703 – 1.02 0.0758 119 1183 exclusion phecode
304 Adjustment reaction Mental Disorders 1.02 0.904 – 1.15 0.741 279 2852 exclusion phecode
305.2 Eating disorder Mental Disorders 0.936 0.76 – 1.15 0.536 87 874 exclusion phecode
306 Other mental disorder Mental Disorders 1 0.988 – 1.01 0.921 26720 223406 exclusion phecode
306.9 Tension headache Mental Disorders 1.06 0.944 – 1.19 0.33 305 3053 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.946 0.75 – 1.19 0.643 73 761 exclusion phecode
313.3 Autism Mental Disorders 0.993 0.743 – 1.33 0.963 51 535 exclusion phecode
315 Develomental delays and disorders Mental Disorders 0.957 0.856 – 1.07 0.447 342 3419 exclusion phecode
315.1 Learning disorder Mental Disorders 0.925 0.788 – 1.09 0.344 159 1580 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.823 0.658 – 1.03 0.0871 87 864 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1 0.975 – 1.03 0.844 5205 52399 exclusion phecode
317 Alcohol-related disorders Mental Disorders 0.994 0.976 – 1.01 0.502 12362 124405 exclusion phecode
317.1 Alcoholism Mental Disorders 0.992 0.97 – 1.01 0.475 8637 87062 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.04 0.972 – 1.12 0.244 822 8297 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.01 0.993 – 1.02 0.295 18601 181065 exclusion phecode
320 Meningitis Neurological 0.956 0.866 – 1.06 0.374 432 4318 exclusion phecode
323 Encephalitis Neurological 0.957 0.854 – 1.07 0.447 327 3323 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 0.674 0.522 – 0.871 0.00259 70 714 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 0.969 0.858 – 1.1 0.616 281 2812 exclusion phecode
327 Sleep disorders Neurological 0.943 0.888 – 1 0.0566 1142 11427 exclusion phecode
327.3 Sleep apnea Neurological 0.983 0.953 – 1.01 0.29 4346 43580 exclusion phecode
327.4 Insomnia Neurological 1.04 0.891 – 1.21 0.625 159 1612 exclusion phecode
327.41 Organic or persistent insomnia Neurological 0.991 0.838 – 1.17 0.915 133 1347 exclusion phecode
331 Other cerebral degenerations Neurological 1.05 0.985 – 1.12 0.135 1088 11048 exclusion phecode
331.1 Hydrocephalus Neurological 1.01 0.919 – 1.11 0.839 471 4812 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.15 1.04 – 1.28 0.0054 415 4183 exclusion phecode
332 Parkinson's disease Neurological 1.02 0.961 – 1.09 0.484 1088 10941 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.987 0.92 – 1.06 0.719 867 8601 exclusion phecode
333.1 Essential tremor Neurological 0.955 0.832 – 1.1 0.518 209 2069 exclusion phecode
333.2 Myoclonus Neurological 1.01 0.823 – 1.24 0.916 95 936 exclusion phecode
333.4 Torsion dystonia Neurological 1.08 0.947 – 1.23 0.252 243 2417 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1 0.953 – 1.05 0.953 1714 17666 exclusion phecode
334.1 Spinocerebellar disease Neurological 0.941 0.774 – 1.15 0.546 110 1137 exclusion phecode
334.2 Anterior horn cell disease Neurological 0.868 0.761 – 0.991 0.0357 236 2370 exclusion phecode
335 Multiple sclerosis Neurological 0.983 0.928 – 1.04 0.55 1274 12847 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.08 0.954 – 1.23 0.215 256 2584 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.14 0.906 – 1.45 0.26 70 700 exclusion phecode
338 Pain Neurological 1.01 0.931 – 1.08 0.894 718 7414 exclusion phecode
338.1 Acute pain Neurological 0.991 0.89 – 1.1 0.862 362 3815 exclusion phecode
338.2 Chronic pain Neurological 1 0.9 – 1.11 0.997 362 3666 exclusion phecode
339 Other headache syndromes Neurological 0.995 0.972 – 1.02 0.686 7463 75424 exclusion phecode
340 Migraine Neurological 1.04 0.997 – 1.08 0.0674 2714 27423 exclusion phecode
340.1 Migrain with aura Neurological 1.06 0.916 – 1.22 0.451 202 2041 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.934 0.819 – 1.07 0.308 244 2464 exclusion phecode
342 Hemiplegia Neurological 0.954 0.904 – 1.01 0.0872 1446 14540 exclusion phecode
343 Infantile cerebral palsy Neurological 1.07 0.905 – 1.27 0.422 143 1415 exclusion phecode
344 Other paralytic syndromes Neurological 0.978 0.901 – 1.06 0.583 632 6437 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.01 0.982 – 1.04 0.44 4840 48885 exclusion phecode
345.1 Epilepsy Neurological 0.997 0.929 – 1.07 0.926 841 8425 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 0.969 0.878 – 1.07 0.526 428 4271 exclusion phecode
345.12 Partial epilepsy Neurological 0.972 0.858 – 1.1 0.651 267 2686 exclusion phecode
345.3 Convulsions Neurological 1.05 1.01 – 1.1 0.0289 2142 21744 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.08 0.902 – 1.29 0.408 131 1398 exclusion phecode
348 Other conditions of brain Neurological 1.03 0.956 – 1.11 0.431 745 7607 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.07 0.94 – 1.22 0.299 251 2586 exclusion phecode
348.4 Cerebral cysts Neurological 0.842 0.7 – 1.01 0.0682 128 1308 exclusion phecode
348.7 Coma Neurological 1.02 0.914 – 1.14 0.727 345 3492 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.05 0.921 – 1.2 0.466 239 2449 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.05 0.944 – 1.17 0.371 372 3792 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.05 0.94 – 1.18 0.381 325 3287 exclusion phecode
350 Abnormal movement Neurological 0.978 0.939 – 1.02 0.292 2536 25904 exclusion phecode
350.1 Abnormal involuntary movements Neurological 0.9 0.838 – 0.967 0.00395 845 8588 exclusion phecode
350.2 Abnormality of gait Neurological 1 0.949 – 1.05 0.984 1502 15466 exclusion phecode
350.3 Lack of coordination Neurological 1.01 0.91 – 1.13 0.807 353 3531 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.954 0.737 – 1.24 0.724 54 522 exclusion phecode
351 Other peripheral nerve disorders Neurological 1 0.986 – 1.02 0.607 11866 119214 exclusion phecode
352 Disorders of other cranial nerves Neurological 0.933 0.881 – 0.987 0.0165 1315 13219 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.996 0.902 – 1.1 0.93 445 4471 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 0.908 0.847 – 0.975 0.00756 846 8492 exclusion phecode
353 Nerve root and plexus disorders Neurological 1.02 0.953 – 1.08 0.642 1067 10922 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.897 0.734 – 1.09 0.283 106 1098 exclusion phecode
353.2 Nerve root lesions Neurological 1.1 0.846 – 1.43 0.482 56 546 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.11 0.942 – 1.32 0.206 149 1489 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.02 0.962 – 1.08 0.525 1282 13335 exclusion phecode
358 Myoneural disorders Neurological 0.896 0.776 – 1.03 0.132 202 2047 exclusion phecode
358.1 Myasthenia gravis Neurological 0.849 0.729 – 0.988 0.0347 183 1863 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.99 0.898 – 1.09 0.849 440 4493 exclusion phecode
359.1 Muscular dystrophies Neurological 1.05 0.872 – 1.26 0.608 119 1185 exclusion phecode
359.2 Myopathy Neurological 0.971 0.868 – 1.09 0.613 337 3474 exclusion phecode
360 Disorders of the globe Sense Organs 0.969 0.866 – 1.09 0.587 325 3255 exclusion phecode
360.2 Progressive myopia Sense Organs 0.899 0.788 – 1.03 0.112 241 2416 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.98 0.945 – 1.02 0.274 3146 31583 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.992 0.938 – 1.05 0.773 1355 13554 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.997 0.79 – 1.26 0.978 67 660 exclusion phecode
362 Other retinal disorders Sense Organs 1.01 0.98 – 1.05 0.419 3649 36924 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.03 0.987 – 1.08 0.165 2057 20817 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.03 0.987 – 1.08 0.17 2054 20788 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.909 0.771 – 1.07 0.255 155 1558 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1.01 0.82 – 1.24 0.941 96 957 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.02 0.951 – 1.1 0.555 814 8244 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 1.03 0.888 – 1.2 0.682 174 1782 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.887 0.709 – 1.11 0.295 80 787 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.917 0.76 – 1.11 0.367 116 1123 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.04 0.885 – 1.22 0.651 164 1640 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.981 0.768 – 1.25 0.879 67 673 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.05 0.966 – 1.14 0.247 623 6236 exclusion phecode
364.1 Corneal opacity Sense Organs 1.05 0.847 – 1.31 0.641 87 886 exclusion phecode
364.2 Corneal edema Sense Organs 0.973 0.774 – 1.22 0.814 76 771 exclusion phecode
364.4 Corneal degenerations Sense Organs 1.04 0.902 – 1.2 0.578 199 1952 exclusion phecode
364.41 Keratoconus Sense Organs 0.999 0.802 – 1.24 0.992 86 856 exclusion phecode
364.5 Corneal dystrophy Sense Organs 1.03 0.89 – 1.2 0.682 199 2011 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 1.23 0.995 – 1.52 0.056 97 967 exclusion phecode
365 Glaucoma Sense Organs 0.988 0.957 – 1.02 0.452 4223 42542 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 0.947 0.888 – 1.01 0.1 997 9987 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.948 0.889 – 1.01 0.108 992 9927 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.993 0.916 – 1.08 0.859 662 6688 exclusion phecode
366 Cataract Sense Organs 0.999 0.984 – 1.01 0.848 19091 162354 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 1.14 0.885 – 1.48 0.306 67 681 exclusion phecode
366.2 Senile cataract Sense Organs 0.994 0.971 – 1.02 0.611 7874 78514 exclusion phecode
366.3 Traumatic cataract Sense Organs 1.03 0.84 – 1.26 0.795 101 1006 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1 0.963 – 1.05 0.835 2319 23161 exclusion phecode
367.1 Myopia Sense Organs 1.01 0.951 – 1.07 0.757 1202 12023 exclusion phecode
367.2 Astigmatism Sense Organs 0.954 0.817 – 1.12 0.555 179 1815 exclusion phecode
367.8 Hypermetropia Sense Organs 0.954 0.84 – 1.09 0.476 248 2414 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.01 0.936 – 1.09 0.761 695 6950 exclusion phecode
368 Visual disturbances Sense Organs 1 0.963 – 1.04 0.954 2809 28635 exclusion phecode
368.1 Amblyopia Sense Organs 1.09 0.998 – 1.19 0.0558 512 5093 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.956 0.885 – 1.03 0.261 691 7085 exclusion phecode
368.3 Anisometropia Sense Organs 1.08 0.913 – 1.29 0.358 145 1493 exclusion phecode
368.4 Visual field defects Sense Organs 1.03 0.923 – 1.15 0.598 323 3242 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.951 0.873 – 1.03 0.242 574 5907 exclusion phecode
369 Infection of the eye Sense Organs 1.06 0.969 – 1.16 0.204 532 5342 exclusion phecode
369.2 Eye infection, viral Sense Organs 1.06 0.873 – 1.28 0.576 119 1199 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 1.01 0.875 – 1.17 0.869 205 2046 exclusion phecode
370 Keratitis Sense Organs 0.943 0.834 – 1.07 0.347 277 2765 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.996 0.841 – 1.18 0.964 136 1366 exclusion phecode
371 Inflammation of the eye Sense Organs 1.01 0.972 – 1.05 0.611 2932 29507 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.04 0.947 – 1.15 0.395 467 4670 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 1.03 0.985 – 1.07 0.194 2263 22829 exclusion phecode
372 Disorders of conjunctiva Sense Organs 0.994 0.922 – 1.07 0.886 731 7347 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.978 0.951 – 1.01 0.111 5466 54729 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.933 0.875 – 0.994 0.0321 1030 10339 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.964 0.918 – 1.01 0.14 1751 17480 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.996 0.952 – 1.04 0.856 2091 21043 exclusion phecode
375.2 Epiphora Sense Organs 1.03 0.96 – 1.1 0.413 850 8549 exclusion phecode
376 Disorders of the orbit Sense Organs 1.13 0.908 – 1.4 0.277 84 831 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.956 0.856 – 1.07 0.43 342 3486 exclusion phecode
377.1 Optic atrophy Sense Organs 1.02 0.781 – 1.33 0.894 54 557 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.21 1.01 – 1.46 0.0441 118 1202 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.04 0.981 – 1.1 0.195 1364 13671 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.04 0.966 – 1.11 0.326 877 8789 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.02 0.883 – 1.18 0.795 208 2091 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.05 0.929 – 1.19 0.428 264 2674 exclusion phecode
379 Other disorders of eye Sense Organs 0.985 0.951 – 1.02 0.387 3542 35724 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.959 0.906 – 1.02 0.15 1304 13189 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.975 0.928 – 1.02 0.314 1725 17435 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.27 0.989 – 1.63 0.0612 66 687 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.06 0.952 – 1.18 0.292 385 3906 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.1 0.938 – 1.28 0.244 158 1636 exclusion phecode
380 Disorders of external ear Sense Organs 0.985 0.907 – 1.07 0.716 626 6239 exclusion phecode
380.1 Otitis externa Sense Organs 1.02 0.935 – 1.12 0.611 495 4958 exclusion phecode
380.4 Impacted cerumen Sense Organs 0.992 0.887 – 1.11 0.893 350 3491 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.973 0.931 – 1.02 0.234 2071 20775 exclusion phecode
381.1 Otitis media Sense Organs 0.971 0.924 – 1.02 0.243 1704 17086 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1 0.933 – 1.08 0.962 821 8256 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 1 0.861 – 1.16 0.995 184 1867 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.839 0.716 – 0.984 0.0306 164 1654 exclusion phecode
381.9 Otorrhea Sense Organs 1.06 0.936 – 1.2 0.354 270 2721 exclusion phecode
382 Otalgia Sense Organs 1.06 0.939 – 1.2 0.351 285 2967 exclusion phecode
383 Otosclerosis Sense Organs 1.02 0.904 – 1.14 0.786 298 3002 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 0.963 0.908 – 1.02 0.201 1259 12587 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 0.968 0.907 – 1.03 0.319 1004 10104 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.04 0.961 – 1.12 0.352 757 7610 exclusion phecode
385.3 Cholesteatoma Sense Organs 1.02 0.939 – 1.11 0.612 585 5911 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.03 0.898 – 1.17 0.713 236 2332 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.975 0.927 – 1.03 0.319 1660 16731 exclusion phecode
386.1 Meniere's disease Sense Organs 0.917 0.841 – 1 0.0528 542 5534 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 1 0.899 – 1.12 0.966 360 3615 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.04 0.96 – 1.12 0.369 741 7417 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.01 0.978 – 1.04 0.557 4374 44351 exclusion phecode
388 Other disorders of ear Sense Organs 1.11 0.951 – 1.28 0.193 195 1949 exclusion phecode
389 Hearing loss Sense Organs 0.998 0.966 – 1.03 0.888 4031 40600 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 1.03 0.938 – 1.14 0.506 442 4399 exclusion phecode
389.2 Conductive hearing loss Sense Organs 0.913 0.828 – 1.01 0.0682 440 4341 exclusion phecode
389.4 Tinnitus Sense Organs 1.11 1.01 – 1.21 0.0239 498 4996 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.01 0.98 – 1.04 0.52 4726 47679 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.02 0.984 – 1.06 0.261 2882 29085 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.01 0.954 – 1.07 0.704 1240 12506 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 0.946 0.888 – 1.01 0.0897 1020 10246 exclusion phecode
395 Heart valve disorders Circulatory System 1.01 0.978 – 1.04 0.548 4067 41116 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.02 0.982 – 1.06 0.309 2781 28107 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.956 0.846 – 1.08 0.475 268 2708 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.04 0.854 – 1.27 0.684 100 1024 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.822 0.673 – 1 0.0549 97 946 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.04 0.987 – 1.1 0.132 1448 14596 exclusion phecode
396 Abnormal heart sounds Circulatory System 0.973 0.911 – 1.04 0.42 974 10029 exclusion phecode
401 Hypertension Circulatory System 1 0.992 – 1.01 0.944 70777 259204 exclusion phecode
401.1 Essential hypertension Circulatory System 1 0.991 – 1.01 0.985 70560 258992 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.01 0.958 – 1.05 0.836 1832 18570 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.04 0.929 – 1.16 0.52 362 3632 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.995 0.944 – 1.05 0.868 1484 15097 exclusion phecode
401.3 Other hypertensive complications Circulatory System 0.998 0.841 – 1.18 0.982 138 1401 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 0.975 0.923 – 1.03 0.364 1415 14377 exclusion phecode
411 Ischemic Heart Disease Circulatory System 0.988 0.976 – 1 0.0449 30497 204338 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.99 0.962 – 1.02 0.49 5029 50315 exclusion phecode
411.2 Myocardial infarction Circulatory System 0.979 0.96 – 0.997 0.0257 11737 110723 exclusion phecode
411.3 Angina pectoris Circulatory System 0.994 0.978 – 1.01 0.487 15474 139847 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 0.983 0.969 – 0.998 0.0278 19828 151239 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.06 0.982 – 1.15 0.134 681 6839 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.991 0.975 – 1.01 0.323 14926 128684 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.964 0.908 – 1.02 0.233 1193 11937 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 0.958 0.912 – 1.01 0.0875 1761 17912 exclusion phecode
414.2 ASCVD Circulatory System 0.939 0.737 – 1.2 0.608 69 710 exclusion phecode
415 Pulmonary heart disease Circulatory System 1 0.969 – 1.03 0.987 4201 43500 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.864 0.681 – 1.1 0.227 72 714 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.989 0.909 – 1.08 0.8 583 5812 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.01 0.917 – 1.12 0.823 433 4320 exclusion phecode
416 Cardiomegaly Circulatory System 0.993 0.954 – 1.03 0.734 2604 26175 exclusion phecode
418 Nonspecific chest pain Circulatory System 1 0.99 – 1.01 0.744 27547 261731 exclusion phecode
418.1 Precordial pain Circulatory System 1.01 0.976 – 1.05 0.557 3424 34403 exclusion phecode
420 Carditis Circulatory System 0.998 0.954 – 1.04 0.926 2013 20517 exclusion phecode
420.1 Myocarditis Circulatory System 1.17 0.966 – 1.41 0.109 125 1241 exclusion phecode
420.2 Pericarditis Circulatory System 0.972 0.918 – 1.03 0.33 1271 13034 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.02 0.893 – 1.17 0.743 220 2178 exclusion phecode
420.22 Chronic pericarditis Circulatory System 0.962 0.792 – 1.17 0.695 109 1103 exclusion phecode
420.3 Endocarditis Circulatory System 1 0.929 – 1.08 0.94 695 7007 exclusion phecode
425 Cardiomyopathy Circulatory System 0.992 0.935 – 1.05 0.779 1224 12422 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.974 0.918 – 1.03 0.387 1191 12079 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.05 0.877 – 1.26 0.591 129 1294 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.04 0.888 – 1.23 0.607 160 1576 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.14 0.889 – 1.47 0.296 59 598 exclusion phecode
426 Cardiac conduction disorders Circulatory System 0.992 0.967 – 1.02 0.528 6708 67513 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 0.975 0.932 – 1.02 0.277 2059 20756 exclusion phecode
426.21 First degree AV block Circulatory System 0.994 0.931 – 1.06 0.869 967 9692 exclusion phecode
426.23 Second degree AV block Circulatory System 0.972 0.883 – 1.07 0.568 441 4452 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 0.939 0.862 – 1.02 0.15 567 5744 exclusion phecode
426.25 Other heart block Circulatory System 1.07 0.894 – 1.28 0.47 126 1284 exclusion phecode
426.3 Bundle branch block Circulatory System 1.02 0.981 – 1.05 0.364 3236 32524 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.01 0.955 – 1.06 0.782 1452 14624 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.02 0.971 – 1.07 0.421 1691 17005 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.08 0.937 – 1.24 0.298 223 2279 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 0.965 0.736 – 1.27 0.798 57 578 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.98 0.94 – 1.02 0.347 2406 24220 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.988 0.945 – 1.03 0.578 2209 22248 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 0.999 0.986 – 1.01 0.912 23323 199753 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.03 0.99 – 1.07 0.147 3081 31117 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.05 1.01 – 1.1 0.0258 2238 22715 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.01 0.941 – 1.08 0.852 921 9222 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 0.996 0.978 – 1.01 0.61 14182 130160 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.971 0.936 – 1.01 0.124 3124 31519 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1 0.945 – 1.07 0.92 1157 11660 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.04 0.928 – 1.16 0.523 333 3385 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.01 0.945 – 1.08 0.782 962 9666 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.996 0.931 – 1.07 0.916 910 9269 exclusion phecode
427.6 Premature beats Circulatory System 0.989 0.904 – 1.08 0.8 517 5209 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 0.993 0.823 – 1.2 0.941 116 1144 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.04 0.992 – 1.09 0.111 2046 21135 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.02 0.916 – 1.13 0.77 388 3909 exclusion phecode
427.9 Palpitations Circulatory System 1.01 0.973 – 1.04 0.679 3619 36633 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1 0.973 – 1.03 0.952 5422 54810 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1 0.959 – 1.05 0.882 2044 20589 exclusion phecode
428.2 Heart failure NOS Circulatory System 1 0.974 – 1.04 0.768 4315 43620 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.03 0.955 – 1.12 0.428 696 6961 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.15 0.874 – 1.51 0.321 61 629 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.05 0.959 – 1.15 0.286 512 5079 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 0.98 0.841 – 1.14 0.796 186 1903 exclusion phecode
430 Intracranial hemorrhage Circulatory System 0.987 0.94 – 1.04 0.581 1822 18251 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.986 0.918 – 1.06 0.708 811 8034 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.01 0.935 – 1.09 0.811 740 7448 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1 0.882 – 1.14 0.98 256 2607 exclusion phecode
433 Cerebrovascular disease Circulatory System 0.994 0.972 – 1.02 0.595 8468 85012 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.979 0.921 – 1.04 0.483 1156 11533 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 0.972 0.85 – 1.11 0.678 220 2191 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.966 0.935 – 0.997 0.0331 4116 41271 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.947 0.9 – 0.997 0.0383 1630 16369 exclusion phecode
433.3 Cerebral ischemia Circulatory System 0.981 0.944 – 1.02 0.328 2792 28132 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 0.991 0.947 – 1.04 0.679 2074 20748 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.01 0.909 – 1.12 0.855 370 3768 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.968 0.914 – 1.03 0.277 1236 12427 exclusion phecode
440 Atherosclerosis Circulatory System 0.991 0.937 – 1.05 0.76 1354 13535 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.834 0.686 – 1.01 0.068 111 1105 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.999 0.928 – 1.08 0.983 788 7931 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 0.956 0.846 – 1.08 0.476 281 2769 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 0.98 0.9 – 1.07 0.639 580 5919 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.992 0.877 – 1.12 0.903 268 2717 exclusion phecode
442 Other aneurysm Circulatory System 0.978 0.933 – 1.03 0.368 1854 18693 exclusion phecode
442.1 Aortic aneurysm Circulatory System 0.984 0.932 – 1.04 0.571 1433 14448 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.98 0.916 – 1.05 0.569 921 9268 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.06 0.865 – 1.29 0.583 102 1012 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.966 0.825 – 1.13 0.672 165 1670 exclusion phecode
442.4 Arterial dissection Circulatory System 0.778 0.59 – 1.03 0.0759 53 536 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 0.941 0.811 – 1.09 0.421 195 1970 exclusion phecode
443 Peripheral vascular disease Circulatory System 0.992 0.959 – 1.03 0.635 3814 38197 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 0.987 0.927 – 1.05 0.68 1094 10916 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.843 0.759 – 0.936 0.0014 381 3817 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 0.998 0.965 – 1.03 0.932 3582 35877 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1 0.961 – 1.04 0.962 2522 25320 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 0.992 0.927 – 1.06 0.829 898 9082 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.949 0.869 – 1.04 0.244 543 5467 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.986 0.915 – 1.06 0.709 786 7907 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.943 0.811 – 1.1 0.443 186 1826 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.02 0.912 – 1.13 0.77 365 3676 exclusion phecode
446.9 Arteritis NOS Circulatory System 0.924 0.806 – 1.06 0.259 234 2335 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.03 0.977 – 1.1 0.249 1301 13049 exclusion phecode
447.1 Stricture of artery Circulatory System 1.04 0.971 – 1.12 0.258 857 8557 exclusion phecode
448 Disease of capillaries Circulatory System 1.14 0.956 – 1.35 0.148 135 1365 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.06 0.968 – 1.15 0.221 526 6739 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.985 0.953 – 1.02 0.374 3733 38577 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.985 0.952 – 1.02 0.407 3501 35961 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1.03 0.938 – 1.12 0.576 519 5468 exclusion phecode
454 Varicose veins Circulatory System 1.03 1.01 – 1.05 0.0142 10698 107824 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1.02 1 – 1.04 0.022 10982 110692 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.955 0.878 – 1.04 0.28 593 6151 exclusion phecode
455 Hemorrhoids Circulatory System 1 0.986 – 1.01 0.989 22689 227493 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.988 0.848 – 1.15 0.878 176 1820 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.939 0.758 – 1.16 0.566 94 938 exclusion phecode
458 Hypotension Circulatory System 1 0.974 – 1.03 0.929 5469 55972 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.01 0.952 – 1.07 0.776 1279 12991 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 0.972 0.85 – 1.11 0.676 228 2272 exclusion phecode
458.9 Hypotension NOS Circulatory System 0.997 0.962 – 1.03 0.869 3292 33918 exclusion phecode
459 Other disorders of circulatory system Circulatory System 0.993 0.977 – 1.01 0.425 15433 155978 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.11 0.935 – 1.32 0.231 132 1381 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 0.992 0.976 – 1.01 0.348 15281 154653 exclusion phecode
464 Acute sinusitis Respiratory 1.13 0.974 – 1.32 0.107 187 1877 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.01 0.961 – 1.05 0.814 2061 22070 exclusion phecode
465.2 Acute pharyngitis Respiratory 1.05 0.969 – 1.13 0.247 735 8102 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.868 0.738 – 1.02 0.0853 159 1594 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.982 0.953 – 1.01 0.249 4558 45576 exclusion phecode
471 Nasal polyps Respiratory 1 0.968 – 1.04 0.853 3227 32267 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.984 0.921 – 1.05 0.636 926 9326 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.01 0.97 – 1.05 0.621 2463 24728 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.05 0.859 – 1.29 0.619 103 1009 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.03 0.898 – 1.17 0.714 245 2562 exclusion phecode
473.4 Voice disturbance Respiratory 1.01 0.95 – 1.08 0.695 1038 10425 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1.01 0.957 – 1.06 0.821 1730 17289 exclusion phecode
474.1 Acute tonsillitis Respiratory 1 0.914 – 1.09 0.998 529 5351 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.03 0.967 – 1.09 0.372 1097 10892 exclusion phecode
475 Chronic sinusitis Respiratory 0.989 0.949 – 1.03 0.588 2507 25089 exclusion phecode
476 Allergic rhinitis Respiratory 0.96 0.9 – 1.02 0.209 1016 10228 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.02 0.973 – 1.06 0.49 2354 23801 exclusion phecode
478 Throat pain Respiratory 0.926 0.832 – 1.03 0.157 361 3647 exclusion phecode
479 Other upper respiratory disease Respiratory 1.01 0.973 – 1.04 0.76 3960 39639 exclusion phecode
480 Pneumonia Respiratory 0.996 0.976 – 1.02 0.73 9840 100504 exclusion phecode
480.1 Bacterial pneumonia Respiratory 0.992 0.967 – 1.02 0.564 6295 64486 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1 0.973 – 1.03 0.975 5576 57104 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.1 0.888 – 1.37 0.379 87 904 exclusion phecode
480.2 Viral pneumonia Respiratory 1.07 0.837 – 1.36 0.605 69 696 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.12 0.916 – 1.37 0.269 95 965 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.03 0.958 – 1.11 0.396 756 7735 exclusion phecode
481 Influenza Respiratory 0.986 0.877 – 1.11 0.807 315 3184 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 1 0.861 – 1.16 0.999 184 1863 exclusion phecode
495 Asthma Respiratory 0.998 0.985 – 1.01 0.759 24392 241857 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.09 0.953 – 1.25 0.208 240 2423 exclusion phecode
496 Chronic airway obstruction Respiratory 1 0.982 – 1.02 0.817 9951 98445 exclusion phecode
496.1 Emphysema Respiratory 0.998 0.949 – 1.05 0.939 1660 16988 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.01 0.975 – 1.05 0.488 2828 28583 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.01 0.969 – 1.05 0.663 2596 26267 exclusion phecode
496.3 Bronchiectasis Respiratory 0.992 0.945 – 1.04 0.744 1779 18136 exclusion phecode
497 Bronchitis Respiratory 1.05 0.962 – 1.14 0.289 599 6054 exclusion phecode
500 Lung disease due to external agents Respiratory 1.06 0.958 – 1.18 0.258 395 4038 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.965 0.77 – 1.21 0.758 79 758 exclusion phecode
500.2 Pneumoconiosis Respiratory 1.07 0.939 – 1.22 0.308 241 2398 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.06 0.974 – 1.15 0.188 633 6423 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.05 0.976 – 1.12 0.199 882 8939 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 0.914 0.831 – 1 0.0626 489 4921 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.09 0.969 – 1.22 0.153 317 3176 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.05 0.8 – 1.38 0.721 59 586 exclusion phecode
506 Empyema and pneumothorax Respiratory 0.982 0.923 – 1.05 0.572 1075 11107 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 0.997 0.971 – 1.02 0.831 5996 62505 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1 0.957 – 1.05 0.889 1897 19342 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.01 0.967 – 1.05 0.726 2493 25256 exclusion phecode
509.1 Respiratory failure Respiratory 1.02 0.971 – 1.06 0.481 1975 20083 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1 0.955 – 1.05 0.903 1722 17547 exclusion phecode
509.5 Respiratory arrest Respiratory 1.01 0.85 – 1.2 0.929 141 1382 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.942 0.848 – 1.05 0.265 380 3743 exclusion phecode
510 Other diseases of lung Respiratory 0.992 0.918 – 1.07 0.833 703 7327 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.01 0.992 – 1.04 0.205 8526 87384 exclusion phecode
512.1 Wheezing Respiratory 1.02 0.885 – 1.18 0.772 211 2129 exclusion phecode
512.2 Painful respiration Respiratory 0.934 0.806 – 1.08 0.363 191 1995 exclusion phecode
512.7 Shortness of breath Respiratory 1.03 1 – 1.06 0.0352 5517 56563 exclusion phecode
512.8 Cough Respiratory 0.981 0.943 – 1.02 0.337 2706 27660 exclusion phecode
512.9 Other dyspnea Respiratory 1.07 1 – 1.15 0.0467 879 8878 exclusion phecode
513 Respiratory abnormalities Respiratory 1.05 0.96 – 1.14 0.303 587 5963 exclusion phecode
513.3 Hypoventilation Respiratory 0.917 0.723 – 1.16 0.474 77 809 exclusion phecode
513.4 Hyperventilation Respiratory 1.09 0.964 – 1.24 0.166 265 2680 exclusion phecode
513.8 Disorders of diaphragm Respiratory 0.93 0.785 – 1.1 0.396 150 1518 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.01 0.968 – 1.06 0.623 2281 23883 exclusion phecode
516 Abnormal sputum Respiratory 1 0.959 – 1.05 0.891 2054 20778 exclusion phecode
516.1 Hemoptysis Respiratory 0.995 0.95 – 1.04 0.833 1996 20201 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.995 0.974 – 1.02 0.677 8840 90880 exclusion phecode
519.2 Respiratory complications Respiratory 1.06 0.937 – 1.19 0.375 304 3159 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1 0.978 – 1.02 0.994 8381 85909 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.938 0.827 – 1.06 0.315 268 2937 exclusion phecode
520 Disorders of tooth development Digestive 1.03 0.98 – 1.07 0.274 1974 19794 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.08 0.818 – 1.42 0.598 51 513 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 1.02 0.976 – 1.06 0.392 2283 22893 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 0.983 0.946 – 1.02 0.381 2894 29405 exclusion phecode
521.1 Dental caries Digestive 0.984 0.947 – 1.02 0.411 2906 29490 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.02 0.972 – 1.07 0.39 1690 17178 exclusion phecode
522.5 Periapical abscess Digestive 1.01 0.952 – 1.08 0.695 1120 11356 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.01 0.963 – 1.07 0.615 1611 16293 exclusion phecode
523.1 Gingivitis Digestive 1.04 0.849 – 1.27 0.711 106 1083 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.04 0.982 – 1.11 0.169 1120 11302 exclusion phecode
523.31 Acute periodontitis Digestive 1.03 0.946 – 1.11 0.53 642 6469 exclusion phecode
523.32 Chronic periodontitis Digestive 1.05 0.956 – 1.14 0.329 534 5409 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.988 0.88 – 1.11 0.831 324 3208 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.996 0.883 – 1.12 0.948 298 2960 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.01 0.972 – 1.05 0.56 2547 25843 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.04 0.802 – 1.35 0.772 69 682 exclusion phecode
526 Diseases of the jaws Digestive 1.04 0.968 – 1.11 0.299 887 8958 exclusion phecode
526.1 Cysts of the jaws Digestive 0.999 0.894 – 1.12 0.98 323 3199 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.882 0.681 – 1.14 0.345 57 590 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.08 0.943 – 1.23 0.275 229 2306 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.09 0.949 – 1.24 0.227 222 2236 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.995 0.817 – 1.21 0.96 102 1058 exclusion phecode
526.9 Jaw disease NOS Digestive 1.09 0.948 – 1.25 0.231 224 2241 exclusion phecode
527 Diseases of the salivary glands Digestive 0.991 0.916 – 1.07 0.832 671 6715 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 0.93 0.746 – 1.16 0.522 82 806 exclusion phecode
527.2 Sialoadenitis Digestive 1.06 0.953 – 1.19 0.273 355 3534 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 0.965 0.744 – 1.25 0.789 60 595 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 0.778 0.642 – 0.942 0.0103 113 1158 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.02 0.988 – 1.06 0.216 3689 37440 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.06 0.958 – 1.17 0.267 414 4512 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.06 0.95 – 1.18 0.304 345 3746 exclusion phecode
528.12 Oral aphthae Digestive 1.11 0.869 – 1.41 0.411 74 818 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.04 0.892 – 1.22 0.587 170 1738 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.985 0.815 – 1.19 0.873 119 1172 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.976 0.788 – 1.21 0.821 91 908 exclusion phecode
528.5 Diseases of lips Digestive 1.06 0.982 – 1.15 0.126 659 6572 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 0.897 0.795 – 1.01 0.079 300 2982 exclusion phecode
528.7 Sialolithiasis Digestive 1.01 0.902 – 1.13 0.845 306 3046 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.02 0.963 – 1.08 0.476 1184 11911 exclusion phecode
529.1 Glossitis Digestive 1.06 0.939 – 1.2 0.341 290 2890 exclusion phecode
530 Diseases of esophagus Digestive 1.01 0.995 – 1.02 0.271 32183 270320 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.01 0.994 – 1.02 0.362 30064 263723 exclusion phecode
530.11 GERD Digestive 1.01 0.996 – 1.02 0.157 21680 218171 exclusion phecode
530.12 Ulcer of esophagus Digestive 0.999 0.97 – 1.03 0.927 5076 50706 exclusion phecode
530.14 Reflux esophagitis Digestive 1.01 0.985 – 1.03 0.6 10122 101202 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.959 0.911 – 1.01 0.107 1625 16282 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1.06 1.01 – 1.11 0.0258 1807 18195 exclusion phecode
530.5 Disorders of esophageal motility Digestive 0.962 0.885 – 1.04 0.354 606 6136 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.1 0.932 – 1.3 0.259 149 1470 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.97 0.866 – 1.09 0.597 333 3332 exclusion phecode
530.9 Heartburn Digestive 1.01 0.965 – 1.06 0.666 1997 20027 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.976 0.953 – 1 0.0586 6880 68976 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.983 0.906 – 1.07 0.69 614 6250 exclusion phecode
531.2 Gastric ulcer Digestive 0.977 0.946 – 1.01 0.17 3966 39549 exclusion phecode
531.3 Duodenal ulcer Digestive 0.96 0.924 – 0.997 0.0351 2902 29284 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 0.959 0.867 – 1.06 0.407 415 4125 exclusion phecode
532 Dysphagia Digestive 0.988 0.962 – 1.01 0.35 6139 62009 exclusion phecode
535 Gastritis and duodenitis Digestive 0.984 0.972 – 0.996 0.0112 27088 252842 exclusion phecode
535.1 Acute gastritis Digestive 0.998 0.939 – 1.06 0.954 1143 11420 exclusion phecode
535.2 Atrophic gastritis Digestive 0.88 0.787 – 0.983 0.0232 358 3565 exclusion phecode
535.6 Duodenitis Digestive 0.964 0.942 – 0.988 0.00299 7382 73936 exclusion phecode
535.8 Other specified gastritis Digestive 1.01 0.985 – 1.03 0.467 7789 77834 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.05 0.871 – 1.26 0.628 120 1150 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.92 0.805 – 1.05 0.225 245 2487 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 0.983 0.949 – 1.02 0.359 3259 32749 exclusion phecode
540 Appendiceal conditions Digestive 1.02 0.985 – 1.06 0.252 3010 30006 exclusion phecode
540.1 Appendicitis Digestive 1.01 0.976 – 1.05 0.477 2824 28138 exclusion phecode
540.11 Acute appendicitis Digestive 1.01 0.965 – 1.05 0.795 2537 25288 exclusion phecode
550 Abdominal hernia Digestive 1 0.991 – 1.01 0.829 44115 273698 exclusion phecode
550.1 Inguinal hernia Digestive 1 0.984 – 1.02 0.989 15711 122486 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.01 0.992 – 1.02 0.414 25417 230563 exclusion phecode
550.3 Femoral hernia Digestive 0.936 0.862 – 1.02 0.114 619 6195 exclusion phecode
550.4 Umbilical hernia Digestive 0.942 0.911 – 0.975 0.000619 3647 36517 exclusion phecode
550.5 Ventral hernia Digestive 0.978 0.944 – 1.01 0.233 3292 33346 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.03 1 – 1.07 0.0369 4281 43184 exclusion phecode
555.1 Regional enteritis Digestive 0.988 0.939 – 1.04 0.642 1674 16786 exclusion phecode
555.2 Ulcerative colitis Digestive 1.06 1.02 – 1.1 0.00275 3058 30957 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.07 0.978 – 1.17 0.144 517 5237 exclusion phecode
556 Ulceration of the lower GI tract Digestive 0.978 0.917 – 1.04 0.5 1022 10222 exclusion phecode
556.1 Ulceration of intestine Digestive 1.01 0.934 – 1.1 0.756 648 6490 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.909 0.806 – 1.03 0.124 287 2894 exclusion phecode
557.1 Celiac disease Digestive 0.874 0.832 – 0.917 5.92e-08 1775 17705 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1 0.985 – 1.02 0.864 14741 149690 exclusion phecode
559 Ileostomy status Digestive 1.03 0.983 – 1.09 0.194 1590 16107 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.03 0.992 – 1.06 0.141 3755 38029 exclusion phecode
560.1 Paralytic ileus Digestive 1.01 0.923 – 1.1 0.836 512 5105 exclusion phecode
560.2 Impaction of intestine Digestive 0.919 0.806 – 1.05 0.209 256 2564 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.03 0.959 – 1.11 0.39 789 8048 exclusion phecode
560.4 Other intestinal obstruction Digestive 1.03 0.993 – 1.07 0.117 3191 32386 exclusion phecode
561 Symptoms involving digestive system Digestive 1.02 1 – 1.03 0.057 15026 151574 exclusion phecode
561.1 Diarrhea Digestive 0.943 0.855 – 1.04 0.234 435 4475 exclusion phecode
561.2 Flatulence Digestive 1.08 1.02 – 1.13 0.00499 1593 16231 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1.01 0.994 – 1.02 0.319 25637 204914 exclusion phecode
562.1 Diverticulosis Digestive 1.01 0.994 – 1.02 0.317 25598 204861 exclusion phecode
563 Constipation Digestive 0.998 0.977 – 1.02 0.831 9758 99467 exclusion phecode
564 Functional digestive disorders Digestive 1 0.986 – 1.01 0.941 20802 203126 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.01 0.98 – 1.04 0.554 5226 52742 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.05 0.995 – 1.1 0.0771 1566 15816 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 0.99 0.973 – 1.01 0.245 14683 147161 exclusion phecode
565 Anal and rectal conditions Digestive 1.01 0.992 – 1.03 0.277 14315 143426 exclusion phecode
565.1 Anal and rectal polyp Digestive 1.02 0.993 – 1.04 0.17 7136 71526 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 0.987 0.921 – 1.06 0.708 889 9069 exclusion phecode
568 Other disorders of peritoneum Digestive 1 0.968 – 1.04 0.81 3112 31324 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.01 0.969 – 1.04 0.755 2957 29747 exclusion phecode
569 Other disorders of intestine Digestive 0.981 0.95 – 1.01 0.263 3965 40472 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.905 0.756 – 1.08 0.278 122 1428 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.01 0.915 – 1.11 0.886 466 4720 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.01 0.974 – 1.05 0.531 2842 28831 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.02 0.967 – 1.07 0.514 1623 16434 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.862 0.71 – 1.05 0.134 111 1097 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 0.94 0.821 – 1.08 0.377 239 2448 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.02 0.959 – 1.1 0.475 944 9617 exclusion phecode
571.81 Portal hypertension Digestive 1.03 0.938 – 1.12 0.561 515 5185 exclusion phecode
572 Ascites (non malignant) Digestive 0.995 0.942 – 1.05 0.862 1397 14929 exclusion phecode
573 Other disorders of liver Digestive 0.987 0.935 – 1.04 0.624 1419 14460 exclusion phecode
573.2 Liver replaced by transplant Digestive 0.93 0.75 – 1.16 0.514 92 945 exclusion phecode
573.3 Hepatomegaly Digestive 1.07 0.947 – 1.2 0.293 285 2899 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 0.996 0.928 – 1.07 0.901 857 8722 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 0.995 0.96 – 1.03 0.774 3286 33501 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.03 0.888 – 1.18 0.731 201 2036 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.02 1 – 1.03 0.0424 14825 149444 exclusion phecode
574.1 Cholelithiasis Digestive 1.01 0.991 – 1.03 0.351 12864 129656 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.985 0.933 – 1.04 0.589 1436 14478 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1 0.976 – 1.03 0.75 5171 51922 exclusion phecode
574.2 Calculus of bile duct Digestive 1.04 0.999 – 1.08 0.0587 2497 25146 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.04 0.997 – 1.08 0.0722 2614 26422 exclusion phecode
575 Other biliary tract disease Digestive 0.981 0.948 – 1.01 0.265 3651 37229 exclusion phecode
575.1 Cholangitis Digestive 0.997 0.907 – 1.1 0.947 481 4815 exclusion phecode
575.2 Obstruction of bile duct Digestive 0.927 0.859 – 1 0.0497 736 7518 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 1.07 0.966 – 1.18 0.206 429 4380 exclusion phecode
575.7 Other disorders of gallbladder Digestive 0.971 0.917 – 1.03 0.301 1321 13542 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.03 0.961 – 1.1 0.425 982 9921 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.989 0.884 – 1.11 0.848 321 3366 exclusion phecode
577 Diseases of pancreas Digestive 1 0.962 – 1.04 0.929 2551 25714 exclusion phecode
577.1 Acute pancreatitis Digestive 0.989 0.944 – 1.04 0.653 1906 19260 exclusion phecode
577.2 Chronic pancreatitis Digestive 0.969 0.885 – 1.06 0.499 509 5040 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.969 0.87 – 1.08 0.56 351 3517 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.993 – 1.02 0.307 19860 199765 exclusion phecode
578.1 Hematemesis Digestive 1.02 0.976 – 1.07 0.349 1887 19075 exclusion phecode
578.2 Blood in stool Digestive 0.999 0.959 – 1.04 0.97 2526 25535 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.01 0.99 – 1.03 0.351 12581 126303 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.01 0.979 – 1.04 0.591 5093 51165 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.03 0.978 – 1.09 0.25 1465 14867 exclusion phecode
579.2 Splenomegaly Digestive 1.02 0.921 – 1.12 0.737 413 4163 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.02 0.967 – 1.07 0.497 1595 15990 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.964 0.914 – 1.02 0.173 1477 14898 exclusion phecode
580.1 Glomerulonephritis Genitourinary 0.986 0.924 – 1.05 0.665 1010 10204 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.917 0.718 – 1.17 0.486 73 716 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.79 0.663 – 0.941 0.00809 131 1319 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.01 0.939 – 1.08 0.816 839 8476 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.898 0.816 – 0.988 0.0275 460 4588 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.958 0.841 – 1.09 0.516 237 2401 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.958 0.844 – 1.09 0.506 244 2471 exclusion phecode
585 Renal failure Genitourinary 0.997 0.973 – 1.02 0.84 6669 67938 exclusion phecode
585.1 Acute renal failure Genitourinary 0.987 0.957 – 1.02 0.425 4323 44204 exclusion phecode
585.2 Renal failure NOS Genitourinary 1 0.947 – 1.06 0.989 1409 14280 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.998 0.958 – 1.04 0.916 2544 25771 exclusion phecode
585.31 Renal dialysis Genitourinary 0.992 0.903 – 1.09 0.873 477 4858 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.03 0.996 – 1.07 0.0836 3238 32690 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.994 0.859 – 1.15 0.937 201 2030 exclusion phecode
586.11 Small kidney Genitourinary 0.996 0.852 – 1.16 0.959 174 1748 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.04 0.976 – 1.1 0.246 1220 12241 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.11 0.888 – 1.39 0.358 78 787 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1 0.938 – 1.08 0.894 874 8878 exclusion phecode
587 Kidney replaced by transpant Genitourinary 0.927 0.832 – 1.03 0.166 350 3604 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 0.983 0.798 – 1.21 0.875 98 954 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 0.792 0.648 – 0.968 0.0227 109 1119 exclusion phecode
590 Pyelonephritis Genitourinary 1.06 0.998 – 1.12 0.0581 1260 12753 exclusion phecode
591 Urinary tract infection Genitourinary 1 0.984 – 1.02 0.747 11735 119390 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.02 0.986 – 1.07 0.212 2840 28450 exclusion phecode
592.1 Cystitis Genitourinary 1.02 0.985 – 1.07 0.228 2780 27825 exclusion phecode
592.11 Acute cystitis Genitourinary 0.983 0.827 – 1.17 0.846 137 1325 exclusion phecode
592.12 Chronic cystitis Genitourinary 1.03 0.961 – 1.11 0.393 847 8511 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.05 0.919 – 1.2 0.466 237 2344 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.01 0.861 – 1.18 0.935 162 1619 exclusion phecode
593 Hematuria Genitourinary 1.01 0.992 – 1.03 0.301 15600 155884 exclusion phecode
594 Urinary calculus Genitourinary 1.02 0.992 – 1.04 0.177 6234 62613 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.02 0.981 – 1.06 0.341 3097 31123 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 0.959 0.89 – 1.03 0.261 764 7686 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.03 0.987 – 1.07 0.17 2367 23720 exclusion phecode
594.8 Renal colic Genitourinary 1.04 0.99 – 1.08 0.128 2008 20149 exclusion phecode
595 Hydronephrosis Genitourinary 0.979 0.933 – 1.03 0.382 1850 18945 exclusion phecode
596 Other disorders of bladder Genitourinary 0.993 0.972 – 1.01 0.522 9500 95543 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.02 0.977 – 1.07 0.331 1957 19625 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 0.984 0.935 – 1.04 0.545 1601 16007 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.01 0.974 – 1.04 0.683 3782 38016 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.99 0.955 – 1.03 0.582 3216 32287 exclusion phecode
597.2 Urinary complications NEC Genitourinary 0.858 0.683 – 1.08 0.188 75 749 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1 0.97 – 1.04 0.809 3437 34518 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.05 0.933 – 1.18 0.425 288 2945 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.996 0.98 – 1.01 0.584 17688 177834 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.882 0.75 – 1.04 0.13 161 1645 exclusion phecode
599.2 Retention of urine Genitourinary 1.01 0.985 – 1.04 0.426 6564 66108 exclusion phecode
599.3 Dysuria Genitourinary 1.04 0.975 – 1.1 0.253 1148 11610 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.996 0.974 – 1.02 0.713 8270 82937 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.01 0.978 – 1.04 0.514 3904 39055 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.15 0.934 – 1.41 0.192 99 1020 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.05 0.802 – 1.37 0.722 58 602 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1.01 0.959 – 1.05 0.817 1873 18791 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.997 0.978 – 1.02 0.794 11082 87821 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 1.01 0.966 – 1.06 0.664 2080 20803 exclusion phecode
601.1 Prostatitis Genitourinary 0.992 0.942 – 1.04 0.763 1562 15634 exclusion phecode
601.11 Acute prostatitis Genitourinary 1.03 0.901 – 1.18 0.671 234 2357 exclusion phecode
601.12 Chronic prostatitis Genitourinary 0.98 0.915 – 1.05 0.552 910 9081 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.966 0.755 – 1.24 0.782 59 588 exclusion phecode
601.4 Balanoposthitis Genitourinary 1.1 0.977 – 1.24 0.114 287 2862 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1 0.892 – 1.12 0.976 303 3017 exclusion phecode
602 Other disorders of prostate Genitourinary 0.993 0.939 – 1.05 0.806 1338 13394 exclusion phecode
603 Other disorders of testis Genitourinary 1.03 0.982 – 1.07 0.243 2146 21499 exclusion phecode
603.1 Hydrocele Genitourinary 1.05 0.995 – 1.11 0.0722 1337 13393 exclusion phecode
604 Disorders of penis Genitourinary 0.996 0.961 – 1.03 0.809 3276 32764 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.01 0.968 – 1.05 0.761 2718 27161 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 1 0.886 – 1.13 0.978 278 2799 exclusion phecode
608 Other disorders of male genital organs Genitourinary 1 0.963 – 1.04 0.97 2820 28217 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.03 0.895 – 1.19 0.678 213 2136 exclusion phecode
609.1 Infertility, male Genitourinary 0.879 0.686 – 1.13 0.31 63 638 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 1.07 0.91 – 1.25 0.427 168 1696 exclusion phecode
610 Benign mammary dysplasias Genitourinary 1.12 1.07 – 1.17 1.96e-06 1883 23623 exclusion phecode
610.1 Cystic mastopathy Genitourinary 1.07 0.995 – 1.16 0.0664 720 8745 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1.09 0.935 – 1.26 0.279 179 2892 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 1 0.863 – 1.16 0.981 184 2871 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 1.15 1.08 – 1.22 4.13e-06 1131 13188 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.08 0.988 – 1.17 0.0906 570 6579 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.03 0.972 – 1.1 0.292 1094 14957 exclusion phecode
611.3 Lump or mass in breast Genitourinary 1.02 0.96 – 1.09 0.498 1062 14482 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.1 1.02 – 1.18 0.0149 747 8533 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.1 1.02 – 1.18 0.0179 715 8164 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 1.1 0.862 – 1.4 0.443 63 688 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 1.05 0.988 – 1.12 0.116 1123 15621 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.01 0.917 – 1.1 0.912 489 6849 exclusion phecode
613.5 Mastodynia Genitourinary 0.982 0.741 – 1.3 0.902 52 735 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 1.04 0.955 – 1.13 0.358 580 6605 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1.26 1.08 – 1.46 0.00319 171 3110 exclusion phecode
613.9 Breast disorder NOS Genitourinary 1 0.846 – 1.19 0.98 139 1937 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.986 0.959 – 1.01 0.328 5351 54199 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.994 0.954 – 1.04 0.794 2404 24133 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.959 0.891 – 1.03 0.268 779 7899 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.801 0.616 – 1.04 0.0963 55 571 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.958 0.865 – 1.06 0.406 397 4011 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.894 0.798 – 1 0.0538 328 3345 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.958 0.844 – 1.09 0.507 250 2642 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.991 0.95 – 1.03 0.673 2427 24640 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.955 0.901 – 1.01 0.129 1229 12479 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.976 0.88 – 1.08 0.65 399 4019 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.06 0.985 – 1.15 0.114 707 7170 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.851 0.746 – 0.971 0.0162 250 2579 exclusion phecode
615 Endometriosis Genitourinary 1.02 0.984 – 1.05 0.306 3799 38316 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 0.984 0.868 – 1.12 0.807 277 2873 exclusion phecode
618 Genital prolapse Genitourinary 1 0.983 – 1.02 0.769 10983 109367 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 1 0.98 – 1.03 0.722 6944 69176 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.983 0.955 – 1.01 0.247 5058 50422 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.824 0.751 – 0.904 4.45e-05 493 4747 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.03 0.946 – 1.11 0.546 635 6336 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 0.989 0.967 – 1.01 0.347 8075 82518 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.998 0.922 – 1.08 0.962 670 6936 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 0.958 0.923 – 0.995 0.0246 3022 31318 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.988 0.949 – 1.03 0.555 2667 27073 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.02 0.966 – 1.07 0.525 1639 16655 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.03 0.973 – 1.09 0.303 1272 12763 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1 0.782 – 1.29 0.983 65 679 exclusion phecode
621 Endometrial hyperplasia Genitourinary 1.08 1.01 – 1.15 0.0245 979 10644 exclusion phecode
622 Polyp of female genital organs Genitourinary 1.02 1 – 1.05 0.0238 9371 98870 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 1.02 0.991 – 1.04 0.202 6936 74136 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 1.04 0.998 – 1.07 0.0613 3160 32418 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.05 0.993 – 1.12 0.0823 1172 12060 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.945 0.877 – 1.02 0.147 730 7402 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.995 0.866 – 1.14 0.943 220 2208 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 0.962 0.87 – 1.06 0.452 397 4080 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.988 0.961 – 1.02 0.384 5521 55090 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.971 0.933 – 1.01 0.136 2725 27372 exclusion phecode
625.1 Dyspareunia Genitourinary 0.933 0.877 – 0.992 0.0258 1130 11313 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.02 1 – 1.04 0.0351 15278 109469 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.02 1 – 1.04 0.0557 13378 104677 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.958 0.783 – 1.17 0.675 100 1059 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1.01 0.992 – 1.04 0.225 9249 87559 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 1.04 0.993 – 1.09 0.0951 1845 18826 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.996 0.963 – 1.03 0.836 3612 36268 exclusion phecode
626.2 Dysmenorrhea Genitourinary 1.02 0.966 – 1.07 0.548 1709 17054 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.931 0.792 – 1.1 0.389 154 1530 exclusion phecode
626.8 Infertility, female Genitourinary 1.01 0.957 – 1.07 0.653 1303 13128 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.994 0.973 – 1.02 0.601 9194 97523 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 0.994 0.972 – 1.02 0.632 7940 84785 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.91 0.774 – 1.07 0.25 166 1711 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.969 0.908 – 1.03 0.329 1000 10418 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1.05 0.933 – 1.18 0.414 297 2931 exclusion phecode
628 Ovarian cyst Genitourinary 1.02 0.993 – 1.06 0.136 4412 45211 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.02 0.992 – 1.05 0.161 5032 35198 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.01 0.954 – 1.08 0.643 1092 10946 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.985 0.879 – 1.1 0.792 318 3184 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.02 0.972 – 1.07 0.443 1912 16882 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1 0.933 – 1.07 0.982 841 8372 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.03 0.972 – 1.09 0.306 1228 11979 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.02 0.974 – 1.06 0.453 2272 19393 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 1.08 0.989 – 1.17 0.0907 597 5972 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.03 0.964 – 1.1 0.399 1038 10442 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 0.985 0.771 – 1.26 0.901 69 676 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.04 0.979 – 1.11 0.201 1087 10778 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.01 0.9 – 1.14 0.839 301 2970 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.02 0.89 – 1.17 0.765 212 2090 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.03 0.88 – 1.22 0.68 152 1484 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.972 0.917 – 1.03 0.345 1219 12107 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.986 0.944 – 1.03 0.546 2166 20249 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.07 0.824 – 1.39 0.617 65 650 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.945 0.836 – 1.07 0.371 271 2665 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.07 0.884 – 1.31 0.469 111 1104 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.09 0.94 – 1.26 0.257 185 1870 exclusion phecode
650 Normal delivery Pregnancy Complications 0.998 0.952 – 1.05 0.951 1870 18412 exclusion phecode
651 Multiple gestation Pregnancy Complications 1.06 0.949 – 1.19 0.295 339 3349 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1 0.953 – 1.05 0.929 1670 16087 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.02 0.969 – 1.08 0.392 1361 13271 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.17 0.912 – 1.49 0.222 70 723 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.99 0.959 – 1.02 0.562 4175 28574 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.08 0.892 – 1.32 0.418 109 1051 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 1 0.958 – 1.05 0.95 2195 17883 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.948 0.867 – 1.04 0.248 521 5167 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 1 0.972 – 1.03 0.911 5179 28548 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.01 0.965 – 1.05 0.777 2469 20539 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.886 0.755 – 1.04 0.137 157 1577 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.976 0.857 – 1.11 0.714 255 2541 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.947 0.731 – 1.23 0.681 60 612 exclusion phecode
679 Complications of in utero procedures Dermatologic 0.943 0.719 – 1.24 0.672 51 513 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 0.99 0.966 – 1.02 0.44 6754 70395 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.06 0.974 – 1.16 0.17 535 5478 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.03 0.941 – 1.13 0.528 497 5024 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.973 0.946 – 1 0.0625 5221 53756 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.975 0.948 – 1 0.0867 5226 53817 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.976 0.948 – 1 0.089 5186 53387 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.11 1.01 – 1.22 0.0235 491 5781 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.06 1 – 1.13 0.0425 1264 13069 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.03 0.987 – 1.08 0.165 2210 22339 exclusion phecode
686.3 Pilonidal cyst Dermatologic 0.981 0.899 – 1.07 0.671 572 5762 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.01 0.901 – 1.12 0.926 343 3500 exclusion phecode
687 Symptoms affecting skin Dermatologic 1.01 0.919 – 1.1 0.898 518 5299 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.03 0.983 – 1.08 0.217 2017 20814 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 0.933 0.822 – 1.06 0.279 265 2736 exclusion phecode
687.3 Changes in skin texture Dermatologic 1.15 0.942 – 1.41 0.166 104 1035 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 0.939 0.903 – 0.976 0.00158 2780 27926 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.987 0.96 – 1.01 0.343 5459 55556 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 1 0.785 – 1.27 0.997 70 702 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 1.01 0.763 – 1.34 0.941 53 527 exclusion phecode
691 Congenital anomalies of skin Dermatologic 1.17 0.961 – 1.42 0.117 112 1155 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 1.03 0.961 – 1.1 0.411 933 9479 exclusion phecode
694.1 Vitiligo Dermatologic 1.2 0.925 – 1.56 0.17 58 574 exclusion phecode
694.2 Other dyschromia Dermatologic 1.03 0.958 – 1.11 0.392 740 7517 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 0.888 0.728 – 1.08 0.241 110 1137 exclusion phecode
695 Erythematous conditions Dermatologic 0.982 0.941 – 1.03 0.408 2247 22923 exclusion phecode
695.1 Toxic erythema Dermatologic 1.03 0.84 – 1.25 0.806 105 1043 exclusion phecode
695.2 Bullous dermatoses Dermatologic 0.993 0.832 – 1.18 0.938 129 1318 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 0.985 0.754 – 1.29 0.913 53 552 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.944 0.746 – 1.2 0.635 69 697 exclusion phecode
695.3 Rosacea Dermatologic 1.11 0.984 – 1.24 0.0899 300 3000 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.09 0.98 – 1.2 0.117 398 3902 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.06 0.886 – 1.27 0.53 125 1238 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.03 0.922 – 1.15 0.583 329 3224 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 0.909 0.844 – 0.98 0.0122 731 7461 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1.03 0.901 – 1.19 0.637 219 2282 exclusion phecode
695.81 Erythema nodosum Dermatologic 1.08 0.854 – 1.37 0.51 71 733 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 0.932 0.845 – 1.03 0.161 427 4540 exclusion phecode
696 Psoriasis and related disorders Dermatologic 1.01 0.962 – 1.05 0.803 2168 21893 exclusion phecode
696.4 Psoriasis Dermatologic 1.01 0.966 – 1.06 0.648 2114 21361 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 1.03 0.979 – 1.08 0.256 1604 16325 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.971 0.898 – 1.05 0.455 692 6836 exclusion phecode
697 Sarcoidosis Dermatologic 0.988 0.903 – 1.08 0.789 510 5188 exclusion phecode
698 Pruritus and related conditions Dermatologic 1.09 1.01 – 1.17 0.0272 752 7527 exclusion phecode
700 Corns and callosities Dermatologic 0.931 0.822 – 1.05 0.255 278 2763 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.02 0.993 – 1.06 0.131 4116 45006 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 1.27 1.02 – 1.6 0.0356 83 845 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.03 0.981 – 1.08 0.245 1969 22605 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 1.01 0.778 – 1.31 0.942 59 579 exclusion phecode
701.4 Keloid scar Dermatologic 1.09 0.942 – 1.27 0.239 182 2073 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 0.937 0.847 – 1.04 0.205 417 4394 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.03 0.833 – 1.27 0.794 97 975 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1 0.972 – 1.03 0.99 5200 52601 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.979 0.939 – 1.02 0.315 2490 24879 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 1.02 0.979 – 1.06 0.385 2903 29611 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.03 0.924 – 1.16 0.563 338 3415 exclusion phecode
703.1 Ingrowing nail Dermatologic 1.04 0.975 – 1.12 0.221 935 9400 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 1.01 0.983 – 1.04 0.423 5073 51172 exclusion phecode
704.1 Alopecia Dermatologic 1.02 0.843 – 1.23 0.867 118 1198 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.887 0.694 – 1.13 0.34 74 734 exclusion phecode
705 Disorders of sweat glands Dermatologic 1.04 0.909 – 1.2 0.549 224 2215 exclusion phecode
705.3 Hidradenitis Dermatologic 1.02 0.88 – 1.19 0.766 182 1804 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.05 0.962 – 1.14 0.278 583 5785 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1.01 0.987 – 1.03 0.379 8013 80635 exclusion phecode
706.1 Acne Dermatologic 1.18 0.934 – 1.5 0.165 75 757 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1.01 0.986 – 1.03 0.487 8466 85173 exclusion phecode
707 Chronic ulcer of skin Dermatologic 0.971 0.926 – 1.02 0.23 1870 19141 exclusion phecode
707.1 Decubitus ulcer Dermatologic 0.984 0.918 – 1.06 0.661 861 8851 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.94 0.907 – 0.975 0.000926 3247 32831 exclusion phecode
709.2 Sicca syndrome Dermatologic 0.874 0.794 – 0.963 0.00651 473 4776 exclusion phecode
709.3 Systemic sclerosis Dermatologic 0.933 0.795 – 1.1 0.398 165 1665 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.927 0.718 – 1.2 0.564 59 618 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.948 0.911 – 0.988 0.0104 2577 26058 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.961 0.882 – 1.05 0.361 581 5890 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 0.982 0.899 – 1.07 0.685 537 5438 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.1 0.951 – 1.28 0.196 187 1899 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.902 0.812 – 1 0.053 386 3903 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 0.938 0.848 – 1.04 0.209 414 4110 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 0.924 0.824 – 1.04 0.176 322 3215 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.11 0.885 – 1.4 0.357 78 781 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.975 0.822 – 1.16 0.766 145 1458 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.06 0.821 – 1.37 0.654 63 662 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.01 0.977 – 1.04 0.627 4590 46275 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.01 0.978 – 1.04 0.572 4161 41863 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.05 1 – 1.11 0.05 1573 16048 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.01 0.826 – 1.23 0.95 110 1078 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.04 0.954 – 1.13 0.395 600 6049 exclusion phecode
716 Other arthropathies Musculoskeletal 0.992 0.981 – 1 0.153 35647 256935 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1 0.967 – 1.04 0.896 3306 33554 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.985 0.969 – 1 0.0876 14915 150303 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 0.991 0.979 – 1 0.101 34200 253946 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.01 0.945 – 1.07 0.859 1094 10903 exclusion phecode
720 Spinal stenosis Musculoskeletal 1 0.967 – 1.04 0.93 3562 35801 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1.02 0.997 – 1.05 0.0832 7431 75200 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.01 0.98 – 1.04 0.511 4798 48447 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.04 0.898 – 1.22 0.57 178 1852 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 1 0.895 – 1.12 0.979 331 3386 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.02 0.997 – 1.04 0.0934 8658 86963 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.02 0.935 – 1.12 0.605 497 4983 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1 0.966 – 1.04 0.821 2718 27318 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.12 0.857 – 1.46 0.411 63 655 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.02 0.993 – 1.06 0.129 4254 42786 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.02 0.931 – 1.12 0.661 497 5043 exclusion phecode
723.1 Torticollis Musculoskeletal 1.17 0.958 – 1.44 0.123 102 1025 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1 0.955 – 1.05 0.999 1963 19868 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 0.998 0.899 – 1.11 0.969 383 3844 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 1.01 0.912 – 1.12 0.824 386 3876 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 0.94 0.724 – 1.22 0.644 58 600 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 0.995 0.944 – 1.05 0.838 1549 15689 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.996 0.979 – 1.01 0.654 14198 141816 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.998 0.977 – 1.02 0.826 9269 92496 exclusion phecode
726.2 Synoviopathy Musculoskeletal 1.03 0.918 – 1.15 0.621 318 3214 exclusion phecode
726.3 Bursitis Musculoskeletal 1.04 0.971 – 1.12 0.251 844 8454 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.99 0.966 – 1.01 0.404 7051 70688 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.981 0.943 – 1.02 0.351 2643 26427 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.826 0.675 – 1.01 0.0628 102 1006 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.982 0.946 – 1.02 0.352 2979 29838 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.964 0.883 – 1.05 0.41 560 5641 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.962 0.86 – 1.08 0.493 336 3416 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.14 0.956 – 1.35 0.148 138 1384 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1 0.969 – 1.04 0.881 3602 36133 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.05 0.95 – 1.16 0.331 402 4004 exclusion phecode
728.7 Fasciitis Musculoskeletal 1 0.969 – 1.04 0.889 3724 37323 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1 0.967 – 1.04 0.936 3407 34185 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.01 0.984 – 1.04 0.433 5696 58101 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.02 0.953 – 1.09 0.568 945 9546 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.926 0.756 – 1.13 0.457 97 982 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.06 0.931 – 1.2 0.39 257 2652 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.07 0.937 – 1.22 0.327 243 2511 exclusion phecode
732 Osteochondropathies Musculoskeletal 1.01 0.922 – 1.12 0.775 453 4545 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.05 0.911 – 1.22 0.489 198 2014 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.02 0.775 – 1.33 0.91 56 564 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 1 0.95 – 1.05 0.959 1553 16986 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.09 0.948 – 1.25 0.231 211 2962 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.933 0.852 – 1.02 0.136 507 5206 exclusion phecode
733.6 Costochondritis Musculoskeletal 0.932 0.775 – 1.12 0.457 124 1220 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1 0.944 – 1.06 0.958 1181 11924 exclusion phecode
733.9 Chondromalacia Musculoskeletal 0.94 0.775 – 1.14 0.532 116 1173 exclusion phecode
735 Acquired foot deformities Musculoskeletal 0.987 0.966 – 1.01 0.238 9051 90789 exclusion phecode
735.1 Flat foot Musculoskeletal 1 0.855 – 1.18 0.973 175 1848 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 0.999 0.97 – 1.03 0.958 4784 47984 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1 0.955 – 1.05 0.912 1825 18237 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.991 0.939 – 1.05 0.734 1461 14783 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.979 0.954 – 1.01 0.113 6255 62528 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1.04 0.985 – 1.09 0.167 1559 15691 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 0.985 0.863 – 1.13 0.828 243 2397 exclusion phecode
737 Curvature of spine Musculoskeletal 0.993 0.932 – 1.06 0.818 1059 10736 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.988 0.925 – 1.05 0.712 994 10087 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1 0.955 – 1.05 0.916 1821 18241 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.02 0.966 – 1.08 0.47 1441 14441 exclusion phecode
739 Contracture of joint Musculoskeletal 1.04 0.942 – 1.14 0.472 471 4698 exclusion phecode
740 Osteoarthrosis Musculoskeletal 0.988 0.975 – 1 0.0622 26358 223479 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.976 0.961 – 0.992 0.00291 16646 163111 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.962 0.941 – 0.984 0.000602 8604 86448 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.979 0.875 – 1.1 0.71 334 3350 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.929 0.852 – 1.01 0.0956 569 5700 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.997 0.978 – 1.02 0.735 11561 117767 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.971 0.937 – 1.01 0.0945 3437 34498 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 1.06 0.861 – 1.32 0.564 98 982 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.04 0.957 – 1.13 0.354 595 5934 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.954 0.805 – 1.13 0.584 145 1486 exclusion phecode
741.4 Joint effusions Musculoskeletal 0.936 0.885 – 0.99 0.0207 1363 13791 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 0.984 0.81 – 1.2 0.871 104 1065 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.925 0.701 – 1.22 0.584 51 515 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.989 0.951 – 1.03 0.589 2774 27658 exclusion phecode
742.1 Loose body in joint Musculoskeletal 0.994 0.887 – 1.11 0.918 322 3262 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.06 0.856 – 1.31 0.603 94 941 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 0.982 0.894 – 1.08 0.697 481 4844 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.994 0.949 – 1.04 0.804 1956 19390 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.992 0.968 – 1.02 0.531 6905 71858 exclusion phecode
743.1 Osteoporosis Musculoskeletal 0.988 0.962 – 1.02 0.383 5809 60678 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 0.992 0.963 – 1.02 0.573 5003 52449 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 0.988 0.902 – 1.08 0.798 498 5118 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 0.98 0.891 – 1.08 0.671 475 4972 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.04 0.964 – 1.12 0.322 772 7831 exclusion phecode
745 Pain in joint Musculoskeletal 1.01 0.982 – 1.03 0.64 7627 76938 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.98 0.942 – 1.02 0.33 2702 27276 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.984 0.944 – 1.02 0.429 2534 25608 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1.05 0.962 – 1.14 0.277 563 5643 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.978 0.852 – 1.12 0.754 225 2307 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.972 0.926 – 1.02 0.268 1748 17745 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1 0.851 – 1.18 0.981 160 1618 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1 0.891 – 1.13 0.965 297 2949 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 1.03 0.946 – 1.11 0.545 652 6670 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.01 0.896 – 1.13 0.927 315 3175 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.07 0.924 – 1.24 0.366 187 1861 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.07 0.96 – 1.2 0.213 335 3462 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.1 0.956 – 1.26 0.189 212 2193 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.972 0.795 – 1.19 0.779 109 1130 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1 0.949 – 1.06 0.935 1468 14841 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.957 0.883 – 1.04 0.287 667 6695 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.948 0.858 – 1.05 0.29 429 4309 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.98 0.851 – 1.13 0.777 220 2214 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.02 0.946 – 1.09 0.641 803 8171 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 1.01 0.914 – 1.12 0.813 407 4153 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.01 0.903 – 1.14 0.818 320 3228 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.984 0.879 – 1.1 0.78 316 3195 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 0.971 0.855 – 1.1 0.649 245 2472 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.99 0.86 – 1.14 0.885 203 2041 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.994 0.784 – 1.26 0.96 73 760 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.942 0.783 – 1.13 0.531 123 1218 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.942 0.744 – 1.19 0.624 73 734 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.957 0.789 – 1.16 0.653 99 1051 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.02 0.923 – 1.13 0.679 413 4090 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.11 0.96 – 1.28 0.16 204 1991 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.07 0.906 – 1.26 0.438 156 1539 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.12 0.92 – 1.37 0.255 104 1012 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.935 0.858 – 1.02 0.122 563 5649 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.908 0.723 – 1.14 0.41 79 778 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.929 0.841 – 1.03 0.143 419 4195 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.943 0.793 – 1.12 0.512 139 1649 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.978 0.743 – 1.29 0.871 51 801 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.99 0.859 – 1.14 0.893 206 2087 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.841 0.681 – 1.04 0.109 94 920 exclusion phecode
760 Back pain Symptoms 0.998 0.978 – 1.02 0.812 10641 107485 exclusion phecode
761 Cervicalgia Symptoms 1.02 0.97 – 1.07 0.444 1714 17304 exclusion phecode
764 Sciatica Symptoms 0.996 0.954 – 1.04 0.842 2278 22854 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.03 0.968 – 1.09 0.353 1116 11313 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.02 0.938 – 1.11 0.642 601 6105 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.955 0.889 – 1.03 0.205 823 8388 exclusion phecode
771.1 Swelling of limb Symptoms 1.02 0.984 – 1.05 0.344 4374 44747 exclusion phecode
772 Symptoms of the muscles Symptoms 0.943 0.869 – 1.02 0.161 632 6387 exclusion phecode
773 Pain in limb Symptoms 1.01 0.982 – 1.04 0.516 5930 59940 exclusion phecode
780 Hypothermia/Chills Symptoms 0.983 0.838 – 1.15 0.837 158 1659 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.01 0.959 – 1.06 0.808 1785 18158 exclusion phecode
782.3 Edema Symptoms 1.06 1 – 1.11 0.0424 1544 15897 exclusion phecode
782.6 Pallor and flushing Symptoms 0.986 0.841 – 1.16 0.859 162 1697 exclusion phecode
783 Fever of unknown origin Symptoms 1.02 0.982 – 1.05 0.364 3475 37922 exclusion phecode
785 Abdominal pain Symptoms 1.01 0.995 – 1.02 0.316 38482 292262 exclusion phecode
788 Syncope and collapse Symptoms 0.994 0.973 – 1.02 0.602 8729 88191 exclusion phecode
789 Nausea and vomiting Symptoms 1 0.985 – 1.02 0.664 10790 111496 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.09 0.916 – 1.29 0.338 143 1445 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.08 0.859 – 1.37 0.499 77 802 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 0.997 0.972 – 1.02 0.837 6184 62714 exclusion phecode
791 Gangrene Symptoms 0.896 0.818 – 0.981 0.0172 520 5379 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1.04 0.843 – 1.28 0.72 95 966 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.965 0.8 – 1.16 0.714 114 1300 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 0.965 0.881 – 1.06 0.437 516 5456 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.08 0.893 – 1.31 0.425 117 1173 exclusion phecode
797 Shock Symptoms 1.03 0.868 – 1.22 0.757 152 1531 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.11 0.905 – 1.35 0.322 102 1005 exclusion phecode
798 Malaise and fatigue Symptoms 1.01 0.97 – 1.04 0.739 3181 32896 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1.03 0.944 – 1.12 0.497 561 5663 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.01 0.985 – 1.04 0.443 6720 67642 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.01 0.963 – 1.06 0.628 1720 17359 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.958 0.814 – 1.13 0.609 162 1630 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.992 0.949 – 1.04 0.737 2081 20930 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 1.02 0.95 – 1.1 0.533 745 7459 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.01 0.963 – 1.05 0.765 2114 21254 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.02 0.973 – 1.07 0.397 1757 17698 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 0.962 0.89 – 1.04 0.332 691 6939 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.985 0.962 – 1.01 0.192 7885 79487 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 0.98 0.932 – 1.03 0.446 1610 16201 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.977 0.949 – 1.01 0.114 4932 49662 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.01 0.958 – 1.07 0.708 1473 14930 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.997 0.962 – 1.03 0.878 3234 32439 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.991 0.936 – 1.05 0.747 1292 13198 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.02 0.945 – 1.1 0.619 760 7589 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.963 0.909 – 1.02 0.206 1263 12641 exclusion phecode
817 Concussion Injuries & Poisonings 0.893 0.781 – 1.02 0.0996 235 2367 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.07 0.98 – 1.18 0.126 506 5089 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.01 0.969 – 1.05 0.712 2897 29043 exclusion phecode
823 Torus fracture Injuries & Poisonings 1 0.95 – 1.05 0.993 1615 16204 exclusion phecode
830 Dislocation Injuries & Poisonings 1.01 0.97 – 1.06 0.537 2040 20395 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.991 0.974 – 1.01 0.293 14824 148273 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.999 0.912 – 1.09 0.977 505 5132 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.985 0.893 – 1.08 0.753 461 4600 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.02 0.987 – 1.05 0.252 4604 50976 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.03 0.86 – 1.24 0.724 130 1516 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 0.999 0.908 – 1.1 0.981 473 4889 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.01 0.958 – 1.06 0.785 1738 17885 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.03 0.972 – 1.1 0.299 1200 12086 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.915 0.882 – 0.95 3.51e-06 3028 30471 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1 0.968 – 1.04 0.805 2914 31400 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.04 0.809 – 1.34 0.754 66 661 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1 0.967 – 1.04 0.96 3399 34307 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.944 0.83 – 1.07 0.375 258 2655 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 0.957 0.827 – 1.11 0.553 191 1911 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.03 0.988 – 1.07 0.174 2825 28437 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1 0.873 – 1.15 0.953 213 2163 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.972 0.758 – 1.25 0.824 68 666 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 0.983 0.951 – 1.02 0.297 3985 39843 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.995 0.752 – 1.32 0.973 53 526 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.924 0.74 – 1.15 0.486 88 877 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.87 0.745 – 1.02 0.0793 170 1731 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 0.949 0.863 – 1.05 0.289 472 4688 exclusion phecode
873 Broken tooth Injuries & Poisonings 1.15 1 – 1.32 0.0424 222 2211 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.09 0.928 – 1.27 0.302 167 1689 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.04 0.885 – 1.22 0.627 149 1536 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.03 0.975 – 1.09 0.273 1282 12839 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.01 0.98 – 1.05 0.464 4096 41482 exclusion phecode
916 Contusion Injuries & Poisonings 0.991 0.938 – 1.05 0.753 1401 14081 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.959 0.822 – 1.12 0.598 171 1728 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.974 0.878 – 1.08 0.624 369 3772 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.978 0.861 – 1.11 0.726 246 2457 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.973 0.929 – 1.02 0.239 1984 20324 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.06 0.913 – 1.22 0.466 206 2167 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.953 0.771 – 1.18 0.653 92 1006 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.14 1.04 – 1.25 0.00571 520 5321 exclusion phecode
947 Urticaria Injuries & Poisonings 1.02 0.914 – 1.14 0.736 354 3563 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.08 0.972 – 1.2 0.151 384 3852 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.92 0.831 – 1.02 0.112 409 4114 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.06 0.936 – 1.21 0.343 259 2585 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.902 0.821 – 0.992 0.0332 475 4825 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.15 0.863 – 1.53 0.339 54 543 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.901 0.709 – 1.14 0.392 73 731 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.01 0.995 – 1.03 0.176 16929 174200 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.01 0.993 – 1.03 0.232 14859 152759 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.04 0.935 – 1.15 0.499 389 4013 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.09 1.01 – 1.17 0.0262 781 8254 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.05 0.937 – 1.17 0.428 340 3571 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.943 – 1.18 0.353 335 3501 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.13 0.982 – 1.3 0.0883 204 2160 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.99 0.875 – 1.12 0.873 267 2773 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.02 0.902 – 1.16 0.74 260 2715 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.989 0.962 – 1.02 0.425 5720 58634 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.01 0.949 – 1.08 0.727 1031 10931 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.98 0.891 – 1.08 0.681 458 4644 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.978 0.883 – 1.08 0.673 394 3949 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.939 0.858 – 1.03 0.171 497 4957 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.931 0.853 – 1.02 0.111 541 5637 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.05 1 – 1.1 0.0356 1884 18988 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.981 0.843 – 1.14 0.807 186 1863 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.953 0.842 – 1.08 0.452 265 2647 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.01 0.806 – 1.26 0.956 82 836 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 0.986 0.812 – 1.2 0.883 106 1053 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.03 0.84 – 1.26 0.788 98 996 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.12 0.867 – 1.44 0.394 61 612 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.08 0.815 – 1.43 0.593 53 561 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.1 0.956 – 1.26 0.185 215 2258 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.07 0.984 – 1.15 0.116 668 6752 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.07 0.922 – 1.24 0.381 195 1937 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.09 0.841 – 1.42 0.507 61 606 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.09 0.897 – 1.32 0.396 104 1030 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 1.03 0.843 – 1.26 0.76 106 1086 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.09 0.88 – 1.36 0.416 85 867 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.01 0.969 – 1.06 0.583 2105 30165 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 0.989 0.95 – 1.03 0.593 2553 29336 exclusion phecode
994.2 Sepsis Injuries & Poisonings 0.989 0.95 – 1.03 0.593 2553 29336 exclusion phecode
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