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Scores Breast cancer [female] UK Biobank (UKB) PheWAS analysis

Breast cancer [female] — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID prsweb-phecode174-1-onco-icogs-er-negative-brca-lassosum-ukb-20200608Legacy LassosumlassosumMichailidou K et al. 2018

Evaluation cohort: UK Biobank (UKB).

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143 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.02 1 – 1.05 0.0424 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.01 0.968 – 1.05 0.752 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.999 0.923 – 1.08 0.981 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 1.06 0.993 – 1.14 0.0763 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.38 1.05 – 1.82 0.0205 55 550 all phecode
010 Tuberculosis Infectious Diseases 1 0.853 – 1.18 0.988 166 1659 all phecode
038 Septicemia Infectious Diseases 1.03 0.994 – 1.06 0.119 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 0.974 0.907 – 1.05 0.464 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 0.919 0.838 – 1.01 0.0747 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 1.01 0.99 – 1.03 0.349 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.01 0.974 – 1.05 0.568 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 0.952 0.905 – 1 0.0577 1641 16433 all phecode
041.4 E. coli Infectious Diseases 0.995 0.957 – 1.03 0.795 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 1.04 0.938 – 1.15 0.479 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.03 0.833 – 1.28 0.763 95 949 all phecode
054 Herpes simplex Infectious Diseases 0.926 0.805 – 1.06 0.278 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 0.941 0.865 – 1.03 0.164 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 1.02 0.801 – 1.3 0.878 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 0.884 0.739 – 1.06 0.175 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 0.921 0.807 – 1.05 0.222 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.04 0.922 – 1.18 0.49 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.01 0.912 – 1.11 0.903 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.995 0.837 – 1.18 0.958 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.996 0.823 – 1.21 0.971 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 0.987 0.926 – 1.05 0.692 1004 10036 all phecode
079 Viral infection Infectious Diseases 1.01 0.975 – 1.05 0.478 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 0.985 0.766 – 1.27 0.906 64 640 all phecode
080 Postoperative infection Infectious Diseases 1.04 1 – 1.07 0.0258 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 0.991 0.951 – 1.03 0.677 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.23 0.969 – 1.56 0.0885 71 709 all phecode
1000 Burns Injuries & Poisonings 0.969 0.891 – 1.05 0.457 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 0.974 0.919 – 1.03 0.391 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1 0.977 – 1.03 0.759 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 0.922 0.82 – 1.04 0.173 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 0.981 0.929 – 1.04 0.491 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 1.01 0.891 – 1.15 0.838 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 1.1 0.96 – 1.25 0.174 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.01 0.949 – 1.08 0.699 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 1.01 0.986 – 1.03 0.469 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 1 0.974 – 1.03 0.971 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1 0.981 – 1.02 0.823 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 1.06 0.872 – 1.29 0.56 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.06 0.949 – 1.19 0.29 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.1 0.852 – 1.41 0.478 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 1 0.969 – 1.03 0.983 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1 0.987 – 1.02 0.671 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.01 0.893 – 1.14 0.897 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 0.984 0.87 – 1.11 0.792 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.77 0.605 – 0.98 0.0334 74 756 all phecode
110.12 Althete's foot Infectious Diseases 0.924 0.78 – 1.1 0.367 141 1410 all phecode
112 Candidiasis Infectious Diseases 0.966 0.924 – 1.01 0.125 2126 21275 all phecode
117 Mycoses Infectious Diseases 0.971 0.856 – 1.1 0.652 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 0.952 0.809 – 1.12 0.551 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 0.966 0.776 – 1.2 0.757 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 0.796 0.63 – 1.01 0.0556 69 689 all phecode
134 Helminthiases Infectious Diseases 1.25 1.04 – 1.5 0.0175 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.22 1 – 1.5 0.0477 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.13 0.98 – 1.3 0.0928 205 2050 all phecode
145 Cancer of mouth Neoplasms 1.02 0.945 – 1.11 0.55 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 1.05 0.94 – 1.18 0.366 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 0.964 0.791 – 1.17 0.714 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.22 0.936 – 1.6 0.141 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.06 0.975 – 1.15 0.179 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 1.03 0.91 – 1.18 0.608 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 1.18 1.04 – 1.34 0.00886 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.8 0.616 – 1.04 0.0954 57 570 all phecode
150 Cancer of esophagus Neoplasms 1.06 0.985 – 1.14 0.115 762 7630 all phecode
151 Cancer of stomach Neoplasms 1.07 0.984 – 1.17 0.109 569 5696 all phecode
153 Colorectal cancer Neoplasms 1.03 0.997 – 1.06 0.0819 4580 45799 all phecode
153.2 Colon cancer Neoplasms 1.04 1.01 – 1.08 0.0256 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1 0.959 – 1.05 0.924 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.985 0.891 – 1.09 0.771 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.89 0.759 – 1.04 0.153 158 1580 all phecode
157 Pancreatic cancer Neoplasms 0.976 0.901 – 1.06 0.549 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.02 0.957 – 1.09 0.555 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.04 1.01 – 1.07 0.00888 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.903 0.781 – 1.05 0.173 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.908 0.785 – 1.05 0.192 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.16 0.997 – 1.34 0.0552 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 1.06 0.81 – 1.38 0.687 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 1.03 0.991 – 1.07 0.133 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.03 0.985 – 1.07 0.201 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 1.01 0.916 – 1.12 0.803 437 4364 all phecode
170.1 Bone cancer Neoplasms 0.988 0.825 – 1.18 0.894 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 1.05 0.935 – 1.18 0.415 331 3303 all phecode
172 Skin cancer Neoplasms 1 0.983 – 1.02 0.95 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.04 0.995 – 1.08 0.0823 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 1.04 0.999 – 1.08 0.0575 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.999 0.979 – 1.02 0.882 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.03 0.95 – 1.11 0.498 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.93 0.801 – 1.08 0.339 181 1818 all phecode
174 Breast cancer Neoplasms 1.31 1.29 – 1.33 8.59e-185 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 1.31 1.29 – 1.34 2.19e-186 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.32 1.29 – 1.34 4.1e-179 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.06 0.88 – 1.29 0.524 115 1148 all phecode
175 Acquired absence of breast Neoplasms 1.35 1.3 – 1.41 1.59e-45 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 0.997 0.954 – 1.04 0.892 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 1.05 0.927 – 1.19 0.44 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.991 0.948 – 1.04 0.708 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 1.07 1.01 – 1.14 0.0171 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 1.06 1.01 – 1.12 0.0305 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.08 1.01 – 1.15 0.0325 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.07 1 – 1.15 0.0381 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.07 0.957 – 1.21 0.223 305 3049 all phecode
185 Cancer of prostate Neoplasms 0.985 0.96 – 1.01 0.281 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 0.982 0.892 – 1.08 0.714 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.77 0.601 – 0.988 0.0395 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 1.01 0.892 – 1.14 0.908 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.974 0.802 – 1.18 0.793 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.997 0.966 – 1.03 0.847 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.05 0.989 – 1.12 0.107 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.06 0.99 – 1.12 0.0971 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.07 0.83 – 1.38 0.605 66 660 all phecode
189.2 Cancer of bladder Neoplasms 0.977 0.937 – 1.02 0.286 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.991 0.948 – 1.04 0.688 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.902 0.765 – 1.06 0.219 144 1439 all phecode
190 Cancer of eye Neoplasms 1.04 0.895 – 1.22 0.584 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.03 0.949 – 1.11 0.506 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 0.994 0.91 – 1.08 0.884 566 5650 all phecode
191.11 Cancer of brain Neoplasms 0.998 0.911 – 1.09 0.96 525 5240 all phecode
193 Thyroid cancer Neoplasms 0.923 0.827 – 1.03 0.158 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 1 0.814 – 1.24 0.965 95 949 all phecode
195 Cancer, suspected or other Neoplasms 1.03 1.02 – 1.05 0.000134 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.03 1.02 – 1.05 0.000125 16267 159497 all phecode
197 Chemotherapy Neoplasms 1.06 1.04 – 1.07 3.23e-14 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 1.11 1.09 – 1.14 1.26e-23 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.14 1.11 – 1.17 3.2e-20 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.11 1.06 – 1.15 5.73e-06 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.06 1.01 – 1.12 0.0188 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.11 1.07 – 1.16 9.36e-08 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.09 1.01 – 1.17 0.0212 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.04 0.992 – 1.08 0.106 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.04 0.899 – 1.21 0.578 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 0.995 0.942 – 1.05 0.843 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 1.1 0.895 – 1.35 0.364 95 950 all phecode
200 Myeloproliferative disease Neoplasms 1.03 0.964 – 1.1 0.398 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 1.03 0.927 – 1.14 0.597 387 3867 all phecode
201 Hodgkin's disease Neoplasms 1 0.883 – 1.14 0.949 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.988 0.947 – 1.03 0.593 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.989 0.942 – 1.04 0.643 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 0.975 0.876 – 1.09 0.649 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 0.952 0.873 – 1.04 0.27 581 5824 all phecode
204 Leukemia Neoplasms 1 0.952 – 1.05 0.978 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 1 0.919 – 1.09 0.977 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.12 0.85 – 1.48 0.421 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.992 0.906 – 1.09 0.865 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 0.917 0.835 – 1.01 0.0716 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.872 0.779 – 0.976 0.0168 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.04 0.884 – 1.23 0.632 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 1.06 0.969 – 1.15 0.212 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 0.984 0.97 – 0.999 0.0357 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.971 0.909 – 1.04 0.376 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.989 0.961 – 1.02 0.442 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.03 0.925 – 1.16 0.554 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.901 0.805 – 1.01 0.0681 318 3187 all phecode
214 Lipoma Neoplasms 1.02 0.989 – 1.04 0.255 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.02 0.987 – 1.05 0.268 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.02 0.961 – 1.09 0.504 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 1.02 0.994 – 1.04 0.151 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.03 0.945 – 1.11 0.542 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.04 0.954 – 1.13 0.391 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 1.02 0.998 – 1.04 0.0754 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 1.02 1 – 1.04 0.0237 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.894 0.801 – 0.998 0.0468 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 1 0.949 – 1.06 0.932 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.03 0.894 – 1.18 0.717 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 1.03 0.881 – 1.22 0.675 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.938 0.8 – 1.1 0.427 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 0.932 0.775 – 1.12 0.454 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.06 0.829 – 1.36 0.637 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.06 0.983 – 1.13 0.139 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.05 0.98 – 1.13 0.159 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.947 0.723 – 1.24 0.692 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.03 0.905 – 1.17 0.662 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.99 0.923 – 1.06 0.777 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.06 0.913 – 1.23 0.438 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.844 0.756 – 0.941 0.00229 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.12 1 – 1.26 0.0434 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.969 0.921 – 1.02 0.234 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.02 0.98 – 1.07 0.313 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.03 0.95 – 1.12 0.439 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.958 0.901 – 1.02 0.176 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.958 0.872 – 1.05 0.376 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.956 0.884 – 1.03 0.268 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.981 0.935 – 1.03 0.429 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 0.984 0.893 – 1.08 0.747 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.08 0.873 – 1.33 0.482 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 0.885 0.745 – 1.05 0.165 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 1.02 1.01 – 1.04 0.0103 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.07 1 – 1.14 0.0362 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1 0.813 – 1.23 0.992 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.02 1.01 – 1.04 0.00853 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 0.961 0.852 – 1.08 0.519 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1 0.873 – 1.15 0.982 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.966 0.839 – 1.11 0.63 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 0.939 0.847 – 1.04 0.23 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.01 0.999 – 1.03 0.0741 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.06 1.02 – 1.1 0.00257 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.997 0.875 – 1.14 0.962 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.2 0.956 – 1.51 0.115 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.03 0.94 – 1.13 0.53 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.17 0.995 – 1.36 0.0575 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.01 0.992 – 1.02 0.326 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.02 0.836 – 1.25 0.824 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.15 0.995 – 1.33 0.0582 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.02 0.951 – 1.08 0.643 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.07 0.981 – 1.18 0.123 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.01 0.936 – 1.09 0.764 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.977 0.863 – 1.11 0.71 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.06 0.954 – 1.17 0.297 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.964 0.809 – 1.15 0.679 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.08 0.967 – 1.21 0.17 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.02 0.967 – 1.08 0.421 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 0.991 0.927 – 1.06 0.783 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.971 0.906 – 1.04 0.395 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.953 0.886 – 1.03 0.2 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.03 0.872 – 1.21 0.737 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.971 0.896 – 1.05 0.464 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.938 0.808 – 1.09 0.4 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.975 0.794 – 1.2 0.808 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.987 0.869 – 1.12 0.845 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.943 0.763 – 1.17 0.586 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.902 0.764 – 1.06 0.222 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.993 0.917 – 1.08 0.87 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.04 0.896 – 1.2 0.634 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.01 0.841 – 1.22 0.878 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.08 0.861 – 1.36 0.494 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.998 0.896 – 1.11 0.976 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.01 0.904 – 1.12 0.893 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.05 0.92 – 1.2 0.473 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.05 0.908 – 1.21 0.527 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 1.04 0.884 – 1.22 0.647 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.05 0.892 – 1.24 0.55 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.974 0.793 – 1.2 0.806 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 0.859 0.728 – 1.01 0.0736 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.996 0.866 – 1.15 0.951 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 0.957 0.723 – 1.27 0.759 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 1 0.932 – 1.07 0.992 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 0.946 0.891 – 1 0.0658 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.935 0.868 – 1.01 0.0752 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.953 0.864 – 1.05 0.331 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.07 0.849 – 1.35 0.56 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.975 0.852 – 1.11 0.707 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 1.14 1.02 – 1.27 0.0245 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.04 0.926 – 1.17 0.49 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.05 0.921 – 1.19 0.48 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.04 0.9 – 1.21 0.565 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.01 0.835 – 1.23 0.887 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.04 0.819 – 1.32 0.742 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1 0.858 – 1.18 0.954 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.991 0.835 – 1.17 0.915 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.994 0.983 – 1.01 0.316 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.994 0.983 – 1.01 0.309 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.992 0.98 – 1 0.158 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.2 0.924 – 1.57 0.17 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.957 0.817 – 1.12 0.587 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.936 0.814 – 1.08 0.357 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.974 0.942 – 1.01 0.121 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 0.968 0.934 – 1 0.0819 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.11 0.92 – 1.35 0.269 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.978 0.899 – 1.06 0.596 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.984 0.901 – 1.07 0.712 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.99 0.947 – 1.04 0.676 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.931 0.858 – 1.01 0.08 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.02 0.915 – 1.13 0.752 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.01 0.952 – 1.07 0.749 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.997 0.85 – 1.17 0.973 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.02 0.991 – 1.04 0.217 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.03 0.999 – 1.07 0.0555 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.09 0.957 – 1.25 0.189 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.01 0.962 – 1.06 0.698 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.06 0.997 – 1.14 0.0632 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.04 0.984 – 1.1 0.17 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.04 0.978 – 1.1 0.211 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 1.05 0.987 – 1.12 0.121 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 0.913 0.756 – 1.1 0.341 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 0.981 0.945 – 1.02 0.333 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 1.1 0.995 – 1.21 0.064 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 1.04 0.863 – 1.24 0.71 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1 0.934 – 1.07 0.989 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.04 0.939 – 1.16 0.419 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.07 0.939 – 1.23 0.298 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.977 0.746 – 1.28 0.866 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.999 0.98 – 1.02 0.93 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 1 0.981 – 1.02 0.968 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 0.983 0.786 – 1.23 0.883 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.81 0.627 – 1.05 0.109 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.915 0.804 – 1.04 0.174 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 0.849 0.736 – 0.98 0.0255 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.864 0.727 – 1.03 0.0975 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.01 0.883 – 1.15 0.907 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 0.997 0.973 – 1.02 0.776 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.996 0.973 – 1.02 0.762 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.946 0.859 – 1.04 0.259 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 0.988 0.929 – 1.05 0.701 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 0.983 0.923 – 1.05 0.592 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 1.01 0.941 – 1.09 0.708 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.996 0.854 – 1.16 0.957 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 0.826 0.711 – 0.961 0.0131 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 1.24 0.948 – 1.62 0.116 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.14 0.963 – 1.34 0.129 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.1 0.844 – 1.44 0.477 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.03 0.833 – 1.28 0.768 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 0.938 0.784 – 1.12 0.481 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1 0.818 – 1.22 0.998 103 1059 all phecode
284 Aplastic anemia Hematopoietic 0.958 0.869 – 1.06 0.387 435 4357 all phecode
285 Other anemias Hematopoietic 1 0.985 – 1.02 0.725 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.976 0.864 – 1.1 0.702 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 1 0.928 – 1.08 0.942 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.998 0.904 – 1.1 0.974 414 4147 all phecode
286 Coagulation defects Hematopoietic 1 0.935 – 1.07 0.967 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 1.03 0.94 – 1.14 0.485 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 1.05 0.852 – 1.28 0.664 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.04 0.92 – 1.17 0.556 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.15 0.881 – 1.51 0.3 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.05 0.838 – 1.3 0.695 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.981 0.883 – 1.09 0.717 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.02 0.968 – 1.07 0.48 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.984 0.824 – 1.18 0.862 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 1.06 0.797 – 1.4 0.703 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 1.02 0.972 – 1.08 0.379 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.11 1.01 – 1.23 0.0382 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.982 0.781 – 1.23 0.878 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 1.07 1.03 – 1.1 0.000191 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 1.08 1.04 – 1.12 5.06e-05 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 1.08 1.04 – 1.12 3.74e-05 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 1.11 0.871 – 1.42 0.39 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.01 0.937 – 1.08 0.872 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.01 0.898 – 1.15 0.819 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 1.03 0.989 – 1.07 0.159 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 1.07 0.978 – 1.17 0.14 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.03 0.912 – 1.16 0.632 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 0.979 0.788 – 1.22 0.847 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.999 0.953 – 1.05 0.972 1929 19281 all phecode
290.1 Dementias Mental Disorders 0.945 0.885 – 1.01 0.089 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 0.918 0.831 – 1.01 0.0922 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 1.03 0.895 – 1.19 0.652 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.05 0.97 – 1.14 0.229 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.18 0.944 – 1.49 0.143 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.958 0.893 – 1.03 0.23 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.1 0.923 – 1.32 0.278 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.02 0.905 – 1.15 0.746 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 0.893 0.81 – 0.984 0.0225 436 4376 all phecode
292 Neurological disorders Mental Disorders 1 0.972 – 1.03 0.893 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.984 0.934 – 1.04 0.561 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.968 0.836 – 1.12 0.666 190 1907 all phecode
292.3 Memory loss Mental Disorders 0.98 0.907 – 1.06 0.621 696 6978 all phecode
292.4 Altered mental status Mental Disorders 1.01 0.969 – 1.06 0.591 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 1.04 0.928 – 1.18 0.468 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 1.01 0.964 – 1.05 0.732 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.955 0.892 – 1.02 0.191 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.06 0.984 – 1.13 0.133 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 1.02 0.94 – 1.11 0.606 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 1.1 0.943 – 1.28 0.228 178 1780 all phecode
295.3 Psychosis Mental Disorders 1.12 0.962 – 1.31 0.143 169 1710 all phecode
296 Mood disorders Mental Disorders 1.01 0.988 – 1.03 0.484 12372 123822 all phecode
296.1 Bipolar Mental Disorders 1.01 0.949 – 1.08 0.75 1059 10599 all phecode
296.2 Depression Mental Disorders 1 0.985 – 1.02 0.657 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 1.02 0.912 – 1.13 0.776 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.949 0.846 – 1.06 0.372 311 3070 all phecode
300 Anxiety disorders Mental Disorders 1.01 0.98 – 1.03 0.693 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 1.01 0.987 – 1.04 0.334 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 0.91 0.769 – 1.08 0.272 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.07 0.991 – 1.16 0.0846 707 7065 all phecode
300.13 Phobia Mental Disorders 0.956 0.875 – 1.05 0.327 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.946 0.793 – 1.13 0.538 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 1.11 0.839 – 1.47 0.461 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 0.992 0.828 – 1.19 0.933 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.999 0.824 – 1.21 0.991 113 1129 all phecode
301 Personality disorders Mental Disorders 0.982 0.877 – 1.1 0.745 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.03 0.855 – 1.25 0.739 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 1.01 0.899 – 1.14 0.825 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1 0.912 – 1.1 0.947 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 1.01 0.903 – 1.12 0.913 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 0.982 0.819 – 1.18 0.842 123 1229 all phecode
304 Adjustment reaction Mental Disorders 1.12 0.999 – 1.26 0.0518 293 2936 all phecode
305.2 Eating disorder Mental Disorders 0.937 0.753 – 1.17 0.56 90 900 all phecode
306 Other mental disorder Mental Disorders 1.02 1 – 1.03 0.0153 28056 230087 all phecode
306.9 Tension headache Mental Disorders 1.03 0.914 – 1.16 0.652 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 0.868 0.682 – 1.1 0.247 76 770 all phecode
313.3 Autism Mental Disorders 0.869 0.651 – 1.16 0.341 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 1.02 0.916 – 1.14 0.696 351 3517 all phecode
315.1 Learning disorder Mental Disorders 1.18 1.01 – 1.39 0.039 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 0.866 0.688 – 1.09 0.217 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 1.01 0.986 – 1.04 0.326 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.975 0.745 – 1.27 0.852 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 1.01 0.996 – 1.03 0.119 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 1.02 1 – 1.05 0.0439 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.04 0.967 – 1.11 0.305 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 1.02 1.01 – 1.04 0.00515 19359 185465 all phecode
320 Meningitis Neurological 1.06 0.965 – 1.17 0.214 444 4447 all phecode
323 Encephalitis Neurological 1.03 0.92 – 1.15 0.631 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 0.944 0.747 – 1.19 0.632 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 0.97 0.859 – 1.1 0.629 292 2916 all phecode
327 Sleep disorders Neurological 1 0.944 – 1.07 0.919 1164 11659 all phecode
327.3 Sleep apnea Neurological 0.994 0.964 – 1.03 0.705 4428 44318 all phecode
327.4 Insomnia Neurological 1.1 0.93 – 1.29 0.275 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 1.06 0.891 – 1.27 0.5 136 1390 all phecode
331 Other cerebral degenerations Neurological 1.03 0.973 – 1.1 0.286 1142 11416 all phecode
331.1 Hydrocephalus Neurological 1 0.915 – 1.1 0.946 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 1.07 0.972 – 1.18 0.163 430 4298 all phecode
332 Parkinson's disease Neurological 1 0.942 – 1.07 0.94 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.986 0.921 – 1.06 0.697 894 8954 all phecode
333.1 Essential tremor Neurological 1.06 0.921 – 1.22 0.422 216 2157 all phecode
333.2 Myoclonus Neurological 0.919 0.751 – 1.12 0.41 96 958 all phecode
333.4 Torsion dystonia Neurological 1.05 0.926 – 1.2 0.433 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 1.06 1.01 – 1.11 0.0156 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 0.959 0.798 – 1.15 0.655 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 1.1 0.966 – 1.26 0.148 245 2446 all phecode
335 Multiple sclerosis Neurological 0.999 0.944 – 1.06 0.971 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 1.08 0.952 – 1.22 0.233 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.12 0.876 – 1.42 0.375 72 719 all phecode
338 Pain Neurological 1 0.931 – 1.08 0.964 768 7692 all phecode
338.1 Acute pain Neurological 0.986 0.889 – 1.09 0.787 394 3937 all phecode
338.2 Chronic pain Neurological 1.02 0.917 – 1.13 0.734 380 3817 all phecode
339 Other headache syndromes Neurological 1.03 1 – 1.05 0.028 7819 78241 all phecode
340 Migraine Neurological 1.02 0.979 – 1.06 0.374 2860 28602 all phecode
340.1 Migrain with aura Neurological 1.16 1.01 – 1.34 0.0387 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.04 0.917 – 1.19 0.516 252 2535 all phecode
342 Hemiplegia Neurological 0.978 0.927 – 1.03 0.401 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 1.07 0.909 – 1.27 0.405 145 1450 all phecode
344 Other paralytic syndromes Neurological 0.943 0.87 – 1.02 0.149 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.01 0.979 – 1.04 0.6 5023 50270 all phecode
345.1 Epilepsy Neurological 0.977 0.911 – 1.05 0.511 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 1.04 0.939 – 1.14 0.474 439 4385 all phecode
345.12 Partial epilepsy Neurological 0.903 0.801 – 1.02 0.0964 277 2776 all phecode
345.3 Convulsions Neurological 0.991 0.949 – 1.04 0.691 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.16 0.979 – 1.38 0.0853 144 1438 all phecode
348 Other conditions of brain Neurological 1.02 0.951 – 1.1 0.539 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 0.962 0.848 – 1.09 0.553 268 2678 all phecode
348.4 Cerebral cysts Neurological 0.965 0.809 – 1.15 0.694 133 1350 all phecode
348.7 Coma Neurological 0.953 0.855 – 1.06 0.391 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.08 0.947 – 1.22 0.26 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 0.916 0.827 – 1.01 0.0928 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.997 0.893 – 1.11 0.957 342 3414 all phecode
350 Abnormal movement Neurological 1.03 0.986 – 1.07 0.215 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 0.978 0.914 – 1.05 0.525 887 8852 all phecode
350.2 Abnormality of gait Neurological 1.04 0.986 – 1.09 0.16 1596 15969 all phecode
350.3 Lack of coordination Neurological 1.07 0.96 – 1.19 0.222 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.812 0.617 – 1.07 0.136 54 540 all phecode
351 Other peripheral nerve disorders Neurological 1.01 0.994 – 1.03 0.172 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 1.04 0.985 – 1.1 0.155 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.07 0.971 – 1.18 0.174 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.03 0.959 – 1.1 0.435 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 0.984 0.926 – 1.05 0.602 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 0.922 0.766 – 1.11 0.388 114 1138 all phecode
353.2 Nerve root lesions Neurological 0.833 0.633 – 1.1 0.193 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.08 0.916 – 1.28 0.358 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.03 0.974 – 1.09 0.303 1361 13648 all phecode
358 Myoneural disorders Neurological 1.07 0.928 – 1.23 0.356 211 2109 all phecode
358.1 Myasthenia gravis Neurological 1.01 0.872 – 1.17 0.878 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 1.02 0.928 – 1.13 0.662 465 4646 all phecode
359.1 Muscular dystrophies Neurological 1.04 0.864 – 1.26 0.669 122 1219 all phecode
359.2 Myopathy Neurological 0.99 0.888 – 1.1 0.86 360 3597 all phecode
360 Disorders of the globe Sense Organs 0.985 0.881 – 1.1 0.784 337 3367 all phecode
360.2 Progressive myopia Sense Organs 0.98 0.862 – 1.11 0.761 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 0.99 0.955 – 1.03 0.599 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.01 0.956 – 1.07 0.712 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 1.12 0.866 – 1.44 0.395 68 680 all phecode
362 Other retinal disorders Sense Organs 1 0.971 – 1.04 0.845 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.993 0.95 – 1.04 0.749 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.993 0.95 – 1.04 0.745 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.06 0.907 – 1.25 0.442 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 1.17 0.954 – 1.43 0.133 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.03 0.965 – 1.11 0.335 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 1.14 0.982 – 1.33 0.0855 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.911 0.724 – 1.14 0.422 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.872 0.721 – 1.06 0.161 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.09 0.94 – 1.28 0.245 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 1.06 0.842 – 1.34 0.607 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.971 0.895 – 1.05 0.477 647 6485 all phecode
364.1 Corneal opacity Sense Organs 1.08 0.862 – 1.34 0.516 90 910 all phecode
364.2 Corneal edema Sense Organs 0.914 0.728 – 1.15 0.438 79 800 all phecode
364.4 Corneal degenerations Sense Organs 0.987 0.853 – 1.14 0.857 201 2017 all phecode
364.41 Keratoconus Sense Organs 0.883 0.708 – 1.1 0.269 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 0.929 0.807 – 1.07 0.305 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 1.04 0.854 – 1.28 0.671 100 1000 all phecode
365 Glaucoma Sense Organs 1.03 0.994 – 1.06 0.116 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 1.01 0.951 – 1.08 0.69 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.01 0.944 – 1.07 0.845 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.09 1.01 – 1.18 0.0245 698 6996 all phecode
366 Cataract Sense Organs 1 0.986 – 1.02 0.961 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 1.19 0.945 – 1.49 0.141 69 700 all phecode
366.2 Senile cataract Sense Organs 0.999 0.977 – 1.02 0.951 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 1.06 0.866 – 1.3 0.569 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.03 0.991 – 1.08 0.13 2408 24092 all phecode
367.1 Myopia Sense Organs 1.02 0.967 – 1.08 0.422 1251 12519 all phecode
367.2 Astigmatism Sense Organs 1.05 0.907 – 1.22 0.495 190 1899 all phecode
367.8 Hypermetropia Sense Organs 0.898 0.788 – 1.02 0.109 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 1.05 0.973 – 1.14 0.203 719 7198 all phecode
368 Visual disturbances Sense Organs 1.01 0.972 – 1.05 0.627 2962 29648 all phecode
368.1 Amblyopia Sense Organs 0.989 0.906 – 1.08 0.811 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.957 0.887 – 1.03 0.262 727 7288 all phecode
368.3 Anisometropia Sense Organs 0.989 0.841 – 1.16 0.896 154 1548 all phecode
368.4 Visual field defects Sense Organs 1.01 0.906 – 1.13 0.827 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 1 0.921 – 1.09 0.98 612 6115 all phecode
369 Infection of the eye Sense Organs 1.04 0.95 – 1.13 0.417 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 1 0.84 – 1.19 0.983 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.991 0.86 – 1.14 0.905 213 2128 all phecode
370 Keratitis Sense Organs 1.05 0.927 – 1.18 0.468 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 1.02 0.86 – 1.21 0.831 141 1408 all phecode
371 Inflammation of the eye Sense Organs 1 0.966 – 1.04 0.909 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1 0.915 – 1.1 0.93 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 1.01 0.964 – 1.05 0.804 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 1.01 0.939 – 1.09 0.789 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 1 0.973 – 1.03 0.989 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 0.945 0.887 – 1.01 0.0786 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 0.996 0.949 – 1.05 0.865 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 1 0.96 – 1.05 0.902 2204 22031 all phecode
375.2 Epiphora Sense Organs 0.982 0.916 – 1.05 0.603 898 8969 all phecode
376 Disorders of the orbit Sense Organs 0.933 0.75 – 1.16 0.529 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.956 0.857 – 1.07 0.417 361 3618 all phecode
377.1 Optic atrophy Sense Organs 1.06 0.816 – 1.38 0.654 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.949 0.787 – 1.14 0.581 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.961 0.909 – 1.02 0.157 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.953 0.89 – 1.02 0.17 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.978 0.851 – 1.13 0.76 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 0.933 0.822 – 1.06 0.28 275 2755 all phecode
379 Other disorders of eye Sense Organs 0.989 0.956 – 1.02 0.528 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 0.985 0.931 – 1.04 0.585 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.978 0.932 – 1.03 0.377 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 0.911 0.72 – 1.15 0.44 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.02 0.917 – 1.12 0.771 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.01 0.865 – 1.19 0.863 169 1690 all phecode
380 Disorders of external ear Sense Organs 0.98 0.904 – 1.06 0.619 642 6413 all phecode
380.1 Otitis externa Sense Organs 1.02 0.927 – 1.11 0.727 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 1.06 0.956 – 1.18 0.261 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1 0.959 – 1.05 0.93 2150 21493 all phecode
381.1 Otitis media Sense Organs 1.01 0.962 – 1.06 0.689 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.01 0.943 – 1.08 0.751 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 0.945 0.817 – 1.09 0.445 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 0.941 0.803 – 1.1 0.45 171 1709 all phecode
381.9 Otorrhea Sense Organs 1.02 0.901 – 1.15 0.764 281 2807 all phecode
382 Otalgia Sense Organs 1 0.895 – 1.13 0.954 308 3084 all phecode
383 Otosclerosis Sense Organs 0.93 0.828 – 1.04 0.217 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.01 0.95 – 1.06 0.852 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 0.998 0.936 – 1.06 0.942 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.04 0.965 – 1.12 0.318 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 1.08 0.996 – 1.18 0.0615 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1 0.876 – 1.14 0.999 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.968 0.921 – 1.02 0.2 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 0.99 0.908 – 1.08 0.819 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 0.897 0.808 – 0.996 0.0423 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 0.995 0.923 – 1.07 0.885 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1 0.971 – 1.03 0.967 4582 45806 all phecode
388 Other disorders of ear Sense Organs 1.09 0.942 – 1.25 0.256 202 2017 all phecode
389 Hearing loss Sense Organs 1 0.971 – 1.03 0.906 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.979 0.888 – 1.08 0.665 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 1.01 0.918 – 1.11 0.814 450 4497 all phecode
389.4 Tinnitus Sense Organs 1.05 0.958 – 1.15 0.307 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1 0.973 – 1.03 0.877 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 1 0.968 – 1.04 0.8 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 0.999 0.943 – 1.06 0.965 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 0.952 0.894 – 1.01 0.128 1058 10566 all phecode
395 Heart valve disorders Circulatory System 1.01 0.976 – 1.04 0.654 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.997 0.96 – 1.04 0.883 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.978 0.864 – 1.11 0.73 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.01 0.821 – 1.25 0.911 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.05 0.856 – 1.3 0.62 97 970 all phecode
395.6 Heart valve replaced Circulatory System 1.01 0.961 – 1.07 0.63 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 0.961 0.902 – 1.02 0.221 1048 10468 all phecode
401 Hypertension Circulatory System 0.995 0.987 – 1 0.268 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 0.995 0.986 – 1 0.226 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.02 0.971 – 1.07 0.474 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 1.1 0.988 – 1.22 0.0843 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.998 0.947 – 1.05 0.928 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 0.971 0.823 – 1.14 0.722 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 0.971 0.921 – 1.02 0.283 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 0.996 0.984 – 1.01 0.475 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.994 0.966 – 1.02 0.688 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 1 0.983 – 1.02 0.895 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 1 0.987 – 1.02 0.671 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 0.991 0.977 – 1.01 0.239 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1 0.927 – 1.08 0.951 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.994 0.977 – 1.01 0.464 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.974 0.918 – 1.03 0.382 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 0.976 0.93 – 1.02 0.322 1823 18228 all phecode
414.2 ASCVD Circulatory System 0.828 0.654 – 1.05 0.117 72 719 all phecode
415 Pulmonary heart disease Circulatory System 1 0.975 – 1.04 0.754 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.2 0.956 – 1.51 0.116 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.932 0.857 – 1.01 0.103 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 0.937 0.85 – 1.03 0.189 448 4475 all phecode
416 Cardiomegaly Circulatory System 0.969 0.931 – 1.01 0.116 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 1.02 1.01 – 1.03 0.00205 28599 270106 all phecode
418.1 Precordial pain Circulatory System 1.02 0.984 – 1.05 0.293 3551 35541 all phecode
420 Carditis Circulatory System 0.988 0.945 – 1.03 0.607 2106 21053 all phecode
420.1 Myocarditis Circulatory System 0.898 0.747 – 1.08 0.25 127 1267 all phecode
420.2 Pericarditis Circulatory System 1.01 0.956 – 1.07 0.693 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 0.996 0.867 – 1.15 0.96 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 0.99 0.821 – 1.2 0.92 113 1129 all phecode
420.3 Endocarditis Circulatory System 0.95 0.881 – 1.03 0.191 719 7194 all phecode
425 Cardiomyopathy Circulatory System 1.01 0.953 – 1.07 0.742 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1 0.948 – 1.07 0.871 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.05 0.88 – 1.26 0.579 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.988 0.844 – 1.16 0.885 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 0.941 0.734 – 1.21 0.632 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 0.996 0.971 – 1.02 0.735 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 0.991 0.947 – 1.04 0.695 2114 21162 all phecode
426.21 First degree AV block Circulatory System 0.98 0.918 – 1.05 0.56 986 9867 all phecode
426.23 Second degree AV block Circulatory System 1.05 0.953 – 1.16 0.327 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 0.951 0.874 – 1.04 0.248 587 5868 all phecode
426.25 Other heart block Circulatory System 1.04 0.876 – 1.24 0.631 131 1318 all phecode
426.3 Bundle branch block Circulatory System 1.01 0.978 – 1.05 0.463 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 1 0.953 – 1.06 0.868 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 1.01 0.962 – 1.06 0.669 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.889 0.777 – 1.02 0.0883 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.18 0.914 – 1.52 0.205 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.992 0.952 – 1.03 0.704 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.997 0.955 – 1.04 0.892 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 0.991 0.978 – 1 0.176 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.01 0.973 – 1.05 0.655 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.01 0.973 – 1.06 0.492 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.981 0.918 – 1.05 0.575 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 0.984 0.968 – 1 0.0715 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.988 0.953 – 1.02 0.514 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.962 0.906 – 1.02 0.199 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.03 0.924 – 1.15 0.595 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 0.96 0.899 – 1.02 0.22 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.929 0.869 – 0.994 0.0319 952 9541 all phecode
427.6 Premature beats Circulatory System 1.01 0.927 – 1.11 0.775 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 0.998 0.826 – 1.21 0.987 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 1 0.961 – 1.05 0.869 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.01 0.911 – 1.12 0.848 402 4029 all phecode
427.9 Palpitations Circulatory System 1.03 0.994 – 1.06 0.111 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.991 0.964 – 1.02 0.5 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 0.983 0.94 – 1.03 0.455 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 0.999 0.969 – 1.03 0.954 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1 0.926 – 1.08 0.99 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 1.12 0.879 – 1.42 0.361 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1 0.914 – 1.1 0.994 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.02 0.883 – 1.17 0.81 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 0.993 0.947 – 1.04 0.774 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.981 0.914 – 1.05 0.586 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 0.993 0.923 – 1.07 0.857 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 0.944 0.834 – 1.07 0.361 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 0.988 0.967 – 1.01 0.294 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.972 0.916 – 1.03 0.35 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 0.957 0.834 – 1.1 0.526 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.96 0.93 – 0.99 0.0106 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.941 0.895 – 0.989 0.0168 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 0.991 0.953 – 1.03 0.629 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 1 0.96 – 1.05 0.862 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 1.06 0.957 – 1.18 0.263 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.961 0.908 – 1.02 0.171 1279 12783 all phecode
440 Atherosclerosis Circulatory System 1.07 1.01 – 1.13 0.0138 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.986 0.812 – 1.2 0.886 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.06 0.99 – 1.14 0.091 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.16 1.03 – 1.3 0.0161 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 0.951 0.877 – 1.03 0.23 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.972 0.86 – 1.1 0.654 283 2827 all phecode
442 Other aneurysm Circulatory System 1 0.956 – 1.05 0.917 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 0.992 0.941 – 1.05 0.775 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.998 0.934 – 1.07 0.955 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.06 0.864 – 1.31 0.566 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.914 0.779 – 1.07 0.269 169 1696 all phecode
442.4 Arterial dissection Circulatory System 1.22 0.92 – 1.61 0.169 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.06 0.913 – 1.22 0.464 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 1 0.969 – 1.04 0.92 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 1.01 0.949 – 1.07 0.766 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.889 0.801 – 0.986 0.0258 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.01 0.972 – 1.04 0.751 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1 0.962 – 1.04 0.931 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.02 0.952 – 1.09 0.587 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1 0.917 – 1.09 0.981 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.04 0.969 – 1.12 0.278 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 0.948 0.818 – 1.1 0.483 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 1.06 0.955 – 1.18 0.27 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 1.08 0.946 – 1.23 0.263 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.02 0.964 – 1.08 0.5 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 1.03 0.961 – 1.1 0.402 868 8712 all phecode
448 Disease of capillaries Circulatory System 0.92 0.772 – 1.09 0.346 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.09 1.01 – 1.18 0.0246 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1 0.971 – 1.04 0.846 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1 0.967 – 1.04 0.974 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 1.04 0.955 – 1.14 0.355 564 5645 all phecode
454 Varicose veins Circulatory System 1.02 1 – 1.04 0.0192 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1.02 1.01 – 1.04 0.0124 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.945 0.87 – 1.03 0.176 624 6325 all phecode
455 Hemorrhoids Circulatory System 0.996 0.983 – 1.01 0.542 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.848 0.724 – 0.992 0.0394 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.13 0.92 – 1.38 0.245 97 967 all phecode
458 Hypotension Circulatory System 1 0.975 – 1.03 0.9 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 1.06 1 – 1.12 0.0498 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 0.844 0.738 – 0.966 0.0136 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 0.994 0.96 – 1.03 0.713 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 1 0.987 – 1.02 0.743 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 0.955 0.807 – 1.13 0.593 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 1 0.987 – 1.02 0.683 16103 159422 all phecode
464 Acute sinusitis Respiratory 0.981 0.848 – 1.14 0.801 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.03 0.989 – 1.08 0.149 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 1.06 0.987 – 1.14 0.11 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.02 0.869 – 1.19 0.847 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.986 0.957 – 1.02 0.369 4654 46553 all phecode
471 Nasal polyps Respiratory 0.999 0.964 – 1.04 0.969 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.998 0.934 – 1.07 0.954 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1 0.961 – 1.04 0.951 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 1.05 0.856 – 1.29 0.642 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.94 0.828 – 1.07 0.34 264 2647 all phecode
473.4 Voice disturbance Respiratory 1.02 0.962 – 1.09 0.461 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 0.979 0.932 – 1.03 0.383 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 0.956 0.875 – 1.04 0.313 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.995 0.937 – 1.06 0.885 1122 11199 all phecode
475 Chronic sinusitis Respiratory 0.991 0.952 – 1.03 0.642 2589 25882 all phecode
476 Allergic rhinitis Respiratory 0.993 0.933 – 1.06 0.825 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1 0.962 – 1.05 0.88 2447 24452 all phecode
478 Throat pain Respiratory 0.945 0.851 – 1.05 0.285 377 3789 all phecode
479 Other upper respiratory disease Respiratory 1.02 0.985 – 1.05 0.298 4074 40737 all phecode
480 Pneumonia Respiratory 1.01 0.99 – 1.03 0.322 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 1.01 0.981 – 1.03 0.62 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 1 0.978 – 1.03 0.721 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 0.978 0.792 – 1.21 0.833 93 929 all phecode
480.2 Viral pneumonia Respiratory 0.971 0.759 – 1.24 0.817 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.09 0.891 – 1.33 0.409 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.02 0.95 – 1.1 0.583 794 7951 all phecode
481 Influenza Respiratory 0.921 0.822 – 1.03 0.157 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.11 0.963 – 1.28 0.15 193 1930 all phecode
495 Asthma Respiratory 1 0.99 – 1.02 0.677 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 1.11 0.98 – 1.27 0.0991 250 2510 all phecode
496 Chronic airway obstruction Respiratory 1.02 1 – 1.04 0.0356 10424 101546 all phecode
496.1 Emphysema Respiratory 1.01 0.96 – 1.06 0.729 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 1.09 1.05 – 1.13 4.83e-06 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.09 1.04 – 1.13 3.51e-05 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 1.01 0.965 – 1.06 0.644 1885 18859 all phecode
497 Bronchitis Respiratory 1.07 0.983 – 1.16 0.125 626 6267 all phecode
500 Lung disease due to external agents Respiratory 1.02 0.919 – 1.12 0.755 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.93 0.741 – 1.17 0.534 79 784 all phecode
500.2 Pneumoconiosis Respiratory 1.09 0.953 – 1.24 0.214 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.03 0.953 – 1.12 0.449 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.02 0.956 – 1.09 0.525 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 0.924 0.843 – 1.01 0.0927 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.99 0.884 – 1.11 0.867 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 0.831 0.642 – 1.08 0.161 61 610 all phecode
506 Empyema and pneumothorax Respiratory 1.01 0.949 – 1.07 0.784 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 1.01 0.985 – 1.04 0.407 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.04 0.997 – 1.09 0.065 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.01 0.971 – 1.05 0.582 2599 26031 all phecode
509.1 Respiratory failure Respiratory 1.02 0.973 – 1.07 0.438 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 1.02 0.967 – 1.07 0.542 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 0.908 0.762 – 1.08 0.28 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.949 0.856 – 1.05 0.317 386 3863 all phecode
510 Other diseases of lung Respiratory 1.03 0.959 – 1.11 0.397 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 1.02 0.998 – 1.04 0.0765 9031 90349 all phecode
512.1 Wheezing Respiratory 0.892 0.78 – 1.02 0.0974 220 2196 all phecode
512.2 Painful respiration Respiratory 0.9 0.78 – 1.04 0.152 207 2075 all phecode
512.7 Shortness of breath Respiratory 1.04 1.01 – 1.07 0.00664 5842 58498 all phecode
512.8 Cough Respiratory 0.982 0.945 – 1.02 0.358 2866 28642 all phecode
512.9 Other dyspnea Respiratory 0.995 0.929 – 1.07 0.888 914 9124 all phecode
513 Respiratory abnormalities Respiratory 0.939 0.864 – 1.02 0.143 611 6112 all phecode
513.3 Hypoventilation Respiratory 0.694 0.551 – 0.874 0.0019 83 830 all phecode
513.4 Hyperventilation Respiratory 1.04 0.922 – 1.17 0.526 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 0.917 0.774 – 1.09 0.32 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 1.05 1.01 – 1.1 0.0176 2465 24673 all phecode
516 Abnormal sputum Respiratory 0.998 0.954 – 1.04 0.917 2132 21335 all phecode
516.1 Hemoptysis Respiratory 0.993 0.949 – 1.04 0.754 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.02 0.994 – 1.04 0.162 9366 93681 all phecode
519.2 Respiratory complications Respiratory 1.03 0.918 – 1.15 0.631 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.02 0.999 – 1.04 0.0596 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.979 0.87 – 1.1 0.725 303 3049 all phecode
520 Disorders of tooth development Digestive 1 0.96 – 1.05 0.844 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.08 0.822 – 1.42 0.586 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 1.02 0.973 – 1.06 0.488 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 0.988 0.951 – 1.03 0.52 3016 30245 all phecode
521.1 Dental caries Digestive 0.983 0.947 – 1.02 0.363 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 0.982 0.936 – 1.03 0.479 1774 17750 all phecode
522.5 Periapical abscess Digestive 0.999 0.941 – 1.06 0.971 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 0.993 0.944 – 1.04 0.792 1681 16812 all phecode
523.1 Gingivitis Digestive 1.07 0.887 – 1.28 0.49 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 0.985 0.928 – 1.05 0.632 1165 11650 all phecode
523.31 Acute periodontitis Digestive 0.981 0.906 – 1.06 0.639 666 6667 all phecode
523.32 Chronic periodontitis Digestive 1.03 0.944 – 1.12 0.507 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.04 0.927 – 1.17 0.497 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.03 0.915 – 1.16 0.616 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.01 0.97 – 1.05 0.657 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.875 0.682 – 1.12 0.294 72 720 all phecode
526 Diseases of the jaws Digestive 0.985 0.921 – 1.05 0.653 928 9279 all phecode
526.1 Cysts of the jaws Digestive 0.915 0.818 – 1.02 0.118 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.11 0.851 – 1.45 0.439 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.04 0.911 – 1.18 0.566 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.03 0.902 – 1.18 0.646 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.996 0.821 – 1.21 0.971 110 1098 all phecode
526.9 Jaw disease NOS Digestive 1.02 0.89 – 1.16 0.822 233 2329 all phecode
527 Diseases of the salivary glands Digestive 0.979 0.906 – 1.06 0.589 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.07 0.859 – 1.34 0.536 84 838 all phecode
527.2 Sialoadenitis Digestive 0.982 0.883 – 1.09 0.738 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 0.815 0.637 – 1.04 0.105 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 0.986 0.814 – 1.19 0.884 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.998 0.966 – 1.03 0.906 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 1.03 0.939 – 1.13 0.524 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.07 0.964 – 1.18 0.214 389 3884 all phecode
528.12 Oral aphthae Digestive 0.911 0.731 – 1.14 0.407 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.03 0.883 – 1.2 0.705 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 0.88 0.735 – 1.05 0.164 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 0.981 0.799 – 1.2 0.858 94 940 all phecode
528.5 Diseases of lips Digestive 1.01 0.931 – 1.09 0.865 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.01 0.903 – 1.14 0.818 308 3079 all phecode
528.7 Sialolithiasis Digestive 0.967 0.862 – 1.08 0.568 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 1.05 0.989 – 1.11 0.111 1232 12312 all phecode
529.1 Glossitis Digestive 1.07 0.948 – 1.2 0.291 299 2986 all phecode
530 Diseases of esophagus Digestive 1.01 0.999 – 1.02 0.068 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.01 1 – 1.02 0.0403 31253 272429 all phecode
530.11 GERD Digestive 1.01 0.997 – 1.02 0.127 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 1.01 0.979 – 1.04 0.633 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 0.999 0.979 – 1.02 0.946 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.968 0.921 – 1.02 0.192 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.02 0.977 – 1.07 0.323 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 0.985 0.908 – 1.07 0.709 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.817 0.691 – 0.965 0.0176 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.945 0.847 – 1.05 0.31 341 3416 all phecode
530.9 Heartburn Digestive 1.02 0.976 – 1.07 0.372 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.999 0.975 – 1.02 0.924 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.998 0.921 – 1.08 0.959 637 6374 all phecode
531.2 Gastric ulcer Digestive 0.998 0.966 – 1.03 0.89 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 0.984 0.948 – 1.02 0.389 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.03 0.934 – 1.14 0.556 427 4268 all phecode
532 Dysphagia Digestive 1.01 0.989 – 1.04 0.269 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 1 0.993 – 1.02 0.429 28078 261548 all phecode
535.1 Acute gastritis Digestive 1.03 0.971 – 1.09 0.332 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 1.04 0.931 – 1.15 0.512 370 3687 all phecode
535.6 Duodenitis Digestive 1.01 0.985 – 1.03 0.475 7592 75928 all phecode
535.8 Other specified gastritis Digestive 1.01 0.989 – 1.03 0.328 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.986 0.817 – 1.19 0.88 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.97 0.853 – 1.1 0.636 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 0.98 0.946 – 1.02 0.263 3391 33907 all phecode
540 Appendiceal conditions Digestive 0.983 0.948 – 1.02 0.373 3088 30890 all phecode
540.1 Appendicitis Digestive 0.973 0.937 – 1.01 0.162 2895 28963 all phecode
540.11 Acute appendicitis Digestive 0.986 0.947 – 1.03 0.502 2601 26019 all phecode
550 Abdominal hernia Digestive 1 0.992 – 1.01 0.739 45429 282640 all phecode
550.1 Inguinal hernia Digestive 0.996 0.979 – 1.01 0.601 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 1 0.991 – 1.02 0.581 26494 238953 all phecode
550.3 Femoral hernia Digestive 0.973 0.897 – 1.06 0.504 651 6504 all phecode
550.4 Umbilical hernia Digestive 1.01 0.972 – 1.04 0.767 3705 37072 all phecode
550.5 Ventral hernia Digestive 0.995 0.961 – 1.03 0.765 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 0.966 0.937 – 0.997 0.0306 4444 44442 all phecode
555.1 Regional enteritis Digestive 0.943 0.897 – 0.991 0.0205 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 0.974 0.938 – 1.01 0.154 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 0.976 0.892 – 1.07 0.585 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 1.02 0.957 – 1.09 0.533 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 0.965 0.891 – 1.05 0.386 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.956 0.848 – 1.08 0.469 299 2987 all phecode
557.1 Celiac disease Digestive 1.04 0.993 – 1.09 0.0938 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 1 0.988 – 1.02 0.585 15492 155105 all phecode
559 Ileostomy status Digestive 1 0.953 – 1.05 0.931 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.01 0.973 – 1.04 0.764 3936 39337 all phecode
560.1 Paralytic ileus Digestive 1.05 0.959 – 1.14 0.302 523 5231 all phecode
560.2 Impaction of intestine Digestive 1.06 0.933 – 1.2 0.374 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.951 0.886 – 1.02 0.166 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 0.998 0.963 – 1.03 0.909 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 1.02 0.999 – 1.03 0.0663 15772 157686 all phecode
561.1 Diarrhea Digestive 0.985 0.895 – 1.08 0.754 466 4653 all phecode
561.2 Flatulence Digestive 1 0.951 – 1.05 0.998 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 0.995 0.982 – 1.01 0.435 26714 211692 all phecode
562.1 Diverticulosis Digestive 0.995 0.982 – 1.01 0.413 26672 211642 all phecode
563 Constipation Digestive 1.01 0.992 – 1.03 0.245 10314 103140 all phecode
564 Functional digestive disorders Digestive 1 0.991 – 1.02 0.533 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.02 0.995 – 1.05 0.107 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 0.97 0.922 – 1.02 0.237 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 1 0.985 – 1.02 0.884 15186 151648 all phecode
565 Anal and rectal conditions Digestive 0.983 0.966 – 0.999 0.0423 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 0.973 0.95 – 0.996 0.0235 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 0.968 0.905 – 1.04 0.346 929 9293 all phecode
568 Other disorders of peritoneum Digestive 1.01 0.979 – 1.05 0.432 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.01 0.978 – 1.05 0.448 3101 30987 all phecode
569 Other disorders of intestine Digestive 0.99 0.959 – 1.02 0.526 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.864 0.726 – 1.03 0.101 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 1.02 0.928 – 1.12 0.706 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.01 0.971 – 1.05 0.655 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.03 0.984 – 1.09 0.182 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.971 0.806 – 1.17 0.754 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 1.02 0.9 – 1.15 0.775 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.962 0.901 – 1.03 0.253 976 9804 all phecode
571.81 Portal hypertension Digestive 0.892 0.816 – 0.975 0.0122 528 5285 all phecode
572 Ascites (non malignant) Digestive 1.01 0.959 – 1.06 0.702 1544 15454 all phecode
573 Other disorders of liver Digestive 0.954 0.905 – 1 0.0758 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 0.735 0.596 – 0.907 0.00417 96 960 all phecode
573.3 Hepatomegaly Digestive 0.958 0.851 – 1.08 0.484 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 0.943 0.881 – 1.01 0.0938 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 0.991 0.957 – 1.03 0.632 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.08 0.936 – 1.24 0.303 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.01 0.991 – 1.02 0.368 15607 156123 all phecode
574.1 Cholelithiasis Digestive 1 0.987 – 1.02 0.605 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.987 0.937 – 1.04 0.631 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1 0.977 – 1.03 0.758 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 0.998 0.959 – 1.04 0.926 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.03 0.989 – 1.07 0.165 2748 27523 all phecode
575 Other biliary tract disease Digestive 1.01 0.98 – 1.05 0.436 3867 38724 all phecode
575.1 Cholangitis Digestive 1.01 0.916 – 1.1 0.907 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 0.954 0.886 – 1.03 0.211 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 1.08 0.985 – 1.19 0.1 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 1.05 0.991 – 1.11 0.104 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 0.988 0.928 – 1.05 0.716 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.01 0.905 – 1.12 0.894 348 3488 all phecode
577 Diseases of pancreas Digestive 0.983 0.945 – 1.02 0.4 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 0.997 0.952 – 1.04 0.881 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 1.01 0.926 – 1.11 0.788 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.961 0.864 – 1.07 0.465 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.995 – 1.02 0.223 20626 206278 all phecode
578.1 Hematemesis Digestive 1.01 0.964 – 1.06 0.687 1958 19564 all phecode
578.2 Blood in stool Digestive 0.997 0.958 – 1.04 0.873 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.02 0.997 – 1.03 0.101 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.01 0.981 – 1.04 0.522 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.03 0.98 – 1.09 0.229 1548 15498 all phecode
579.2 Splenomegaly Digestive 0.98 0.888 – 1.08 0.688 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1 0.951 – 1.05 0.975 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.01 0.963 – 1.07 0.59 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 0.99 0.929 – 1.05 0.756 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.904 0.709 – 1.15 0.417 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1 0.838 – 1.2 0.993 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.988 0.922 – 1.06 0.723 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.1 0.999 – 1.21 0.0533 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.988 0.866 – 1.13 0.858 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.995 0.873 – 1.13 0.935 253 2529 all phecode
585 Renal failure Genitourinary 0.999 0.975 – 1.02 0.925 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 1 0.972 – 1.03 0.874 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 0.984 0.933 – 1.04 0.553 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1 0.961 – 1.04 0.972 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 0.956 0.87 – 1.05 0.343 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.05 1.01 – 1.08 0.0126 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.941 0.817 – 1.08 0.395 208 2089 all phecode
586.11 Small kidney Genitourinary 0.948 0.813 – 1.1 0.493 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.06 0.997 – 1.12 0.0623 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.959 0.775 – 1.19 0.702 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.05 0.98 – 1.12 0.169 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 1.04 0.932 – 1.16 0.49 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.02 0.83 – 1.26 0.845 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 0.86 0.715 – 1.03 0.11 116 1158 all phecode
590 Pyelonephritis Genitourinary 1.04 0.982 – 1.1 0.182 1328 13285 all phecode
591 Urinary tract infection Genitourinary 1.02 1 – 1.04 0.0216 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 0.99 0.954 – 1.03 0.617 2966 29661 all phecode
592.1 Cystitis Genitourinary 0.991 0.954 – 1.03 0.647 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 0.858 0.717 – 1.03 0.0959 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 1.01 0.946 – 1.08 0.706 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 1.03 0.904 – 1.17 0.662 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.02 0.868 – 1.19 0.844 165 1662 all phecode
593 Hematuria Genitourinary 1.01 0.99 – 1.02 0.434 16068 160204 all phecode
594 Urinary calculus Genitourinary 0.999 0.974 – 1.03 0.952 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 0.989 0.954 – 1.03 0.563 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 0.953 0.885 – 1.03 0.203 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 1 0.964 – 1.05 0.817 2401 24024 all phecode
594.8 Renal colic Genitourinary 1.03 0.984 – 1.08 0.204 2050 20500 all phecode
595 Hydronephrosis Genitourinary 1.02 0.971 – 1.07 0.476 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 1 0.979 – 1.02 0.994 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 1.04 0.998 – 1.09 0.0633 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 1 0.95 – 1.05 0.987 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.01 0.975 – 1.04 0.654 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.01 0.979 – 1.05 0.423 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 1.1 0.876 – 1.37 0.419 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 1 0.968 – 1.04 0.9 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.12 0.999 – 1.26 0.0511 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.991 – 1.02 0.442 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 0.936 0.796 – 1.1 0.425 166 1670 all phecode
599.2 Retention of urine Genitourinary 1 0.975 – 1.03 0.982 6718 67168 all phecode
599.3 Dysuria Genitourinary 0.967 0.911 – 1.02 0.255 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 1.01 0.99 – 1.03 0.29 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1 0.973 – 1.04 0.778 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 0.994 0.815 – 1.21 0.952 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 0.847 0.657 – 1.09 0.202 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 0.98 0.935 – 1.03 0.403 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 1 0.984 – 1.02 0.705 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.982 0.939 – 1.03 0.422 2081 20818 all phecode
601.1 Prostatitis Genitourinary 0.968 0.919 – 1.02 0.218 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 0.928 0.812 – 1.06 0.271 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 0.934 0.873 – 1 0.0498 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 0.857 0.655 – 1.12 0.259 59 588 all phecode
601.4 Balanoposthitis Genitourinary 1 0.885 – 1.13 0.972 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.09 0.967 – 1.22 0.166 303 3019 all phecode
602 Other disorders of prostate Genitourinary 0.988 0.934 – 1.05 0.679 1341 13408 all phecode
603 Other disorders of testis Genitourinary 0.992 0.949 – 1.04 0.723 2150 21512 all phecode
603.1 Hydrocele Genitourinary 1.03 0.97 – 1.09 0.363 1339 13402 all phecode
604 Disorders of penis Genitourinary 1.01 0.978 – 1.05 0.447 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.02 0.984 – 1.07 0.246 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.02 0.906 – 1.15 0.737 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 0.998 0.96 – 1.04 0.916 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.9 0.78 – 1.04 0.147 214 2138 all phecode
609.1 Infertility, male Genitourinary 1.01 0.783 – 1.3 0.938 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.897 0.763 – 1.05 0.188 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 1.12 1.07 – 1.16 9.67e-08 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 1.13 1.06 – 1.21 0.00027 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.15 1.02 – 1.29 0.0186 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 1.19 1.06 – 1.34 0.00336 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 1.11 1.05 – 1.17 0.000225 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.11 1.03 – 1.2 0.00572 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.13 1.08 – 1.19 2.41e-06 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 1.25 0.956 – 1.63 0.103 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 1.13 1.07 – 1.19 4.39e-06 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.12 1.05 – 1.2 0.00097 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.13 1.05 – 1.21 0.000784 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 1.03 0.816 – 1.3 0.801 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 1.2 1.14 – 1.26 8.01e-13 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.15 1.06 – 1.24 0.00039 720 7210 all phecode
613.5 Mastodynia Genitourinary 1.23 0.982 – 1.55 0.0714 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 1.21 1.12 – 1.3 1.89e-06 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 1.24 1.11 – 1.39 0.000195 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 1.17 1.02 – 1.34 0.025 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.01 0.985 – 1.04 0.376 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.02 0.983 – 1.07 0.266 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.02 0.949 – 1.09 0.61 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.05 0.797 – 1.39 0.721 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.07 0.965 – 1.18 0.212 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.982 0.88 – 1.1 0.751 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.04 0.92 – 1.18 0.53 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.998 0.959 – 1.04 0.927 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1 0.949 – 1.06 0.881 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.08 0.977 – 1.19 0.135 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.972 0.902 – 1.05 0.454 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.989 0.874 – 1.12 0.867 274 2737 all phecode
615 Endometriosis Genitourinary 1.02 0.992 – 1.06 0.14 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 0.982 0.872 – 1.11 0.761 304 3037 all phecode
618 Genital prolapse Genitourinary 1.02 1 – 1.04 0.0397 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1.01 0.99 – 1.04 0.271 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.01 0.982 – 1.04 0.488 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.999 0.912 – 1.09 0.975 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.06 0.977 – 1.14 0.17 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 1.02 0.998 – 1.04 0.0762 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.985 0.913 – 1.06 0.694 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1.01 0.977 – 1.05 0.507 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1 0.962 – 1.04 0.996 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.05 0.999 – 1.1 0.0574 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.05 0.998 – 1.11 0.06 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 1 0.803 – 1.26 0.971 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 1.04 0.981 – 1.11 0.176 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 1.04 1.02 – 1.06 8.71e-05 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 1.03 1.01 – 1.06 0.00571 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 1.06 1.02 – 1.09 0.00247 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.03 0.976 – 1.1 0.253 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 0.96 0.893 – 1.03 0.262 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.95 0.831 – 1.09 0.452 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.972 0.883 – 1.07 0.562 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 1 0.974 – 1.03 0.955 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.02 0.978 – 1.06 0.41 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 1.03 0.968 – 1.09 0.373 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.02 1.01 – 1.04 0.00597 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.02 1.01 – 1.04 0.0105 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 1 0.832 – 1.21 0.968 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.02 0.994 – 1.04 0.155 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 1.06 1.01 – 1.11 0.0129 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 1.04 1 – 1.07 0.0336 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 0.986 0.94 – 1.04 0.575 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.854 0.727 – 1 0.0531 159 1587 all phecode
626.8 Infertility, female Genitourinary 0.999 0.945 – 1.06 0.985 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.03 1.01 – 1.05 0.00416 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 1.03 1.01 – 1.06 0.00234 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 0.883 0.759 – 1.03 0.106 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.998 0.939 – 1.06 0.956 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.989 0.881 – 1.11 0.857 310 3097 all phecode
628 Ovarian cyst Genitourinary 0.985 0.956 – 1.02 0.325 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.01 0.979 – 1.04 0.588 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.989 0.93 – 1.05 0.713 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.1 0.987 – 1.23 0.0833 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.04 0.997 – 1.09 0.067 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.03 0.962 – 1.11 0.382 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.03 0.977 – 1.1 0.249 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.03 0.991 – 1.08 0.125 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 1.05 0.968 – 1.14 0.239 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.08 1.02 – 1.15 0.0128 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 1.1 0.863 – 1.41 0.43 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.03 0.971 – 1.1 0.301 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.998 0.887 – 1.12 0.97 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.06 0.922 – 1.21 0.421 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.09 0.924 – 1.28 0.316 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.03 0.969 – 1.09 0.375 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.04 0.992 – 1.08 0.109 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.44 1.12 – 1.86 0.0052 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.09 0.968 – 1.24 0.149 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.3 1.07 – 1.57 0.00881 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.17 1.01 – 1.35 0.0306 193 1922 all phecode
650 Normal delivery Pregnancy Complications 1.02 0.976 – 1.07 0.354 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 1.01 0.901 – 1.12 0.917 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1.01 0.959 – 1.06 0.748 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.01 0.954 – 1.06 0.801 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.22 0.963 – 1.55 0.0998 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.994 0.963 – 1.03 0.731 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.946 0.783 – 1.14 0.561 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.995 0.953 – 1.04 0.834 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.958 0.877 – 1.05 0.338 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 1.03 1 – 1.06 0.0363 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.02 0.981 – 1.07 0.291 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.02 0.862 – 1.2 0.841 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.13 1 – 1.28 0.0494 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.971 0.747 – 1.26 0.826 63 624 all phecode
679 Complications of in utero procedures Dermatologic 0.929 0.703 – 1.23 0.606 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 0.99 0.966 – 1.01 0.394 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.03 0.945 – 1.12 0.502 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1 0.914 – 1.09 0.994 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.975 0.948 – 1 0.0698 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.975 0.948 – 1 0.072 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.973 0.946 – 1 0.0522 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.08 0.991 – 1.17 0.0802 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.06 1 – 1.12 0.0418 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 1 0.96 – 1.05 0.927 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 1.02 0.938 – 1.11 0.624 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 0.989 0.889 – 1.1 0.836 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1.08 0.99 – 1.18 0.0841 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.02 0.973 – 1.06 0.447 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.12 0.991 – 1.26 0.0689 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 0.963 0.792 – 1.17 0.708 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.06 1.02 – 1.1 0.00572 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.02 0.991 – 1.05 0.19 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.774 0.609 – 0.983 0.0357 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.671 0.506 – 0.89 0.00558 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 1.2 0.996 – 1.44 0.055 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 1.01 0.948 – 1.08 0.728 986 9854 all phecode
694.1 Vitiligo Dermatologic 0.941 0.727 – 1.22 0.644 60 599 all phecode
694.2 Other dyschromia Dermatologic 1 0.934 – 1.08 0.906 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 0.967 0.797 – 1.17 0.732 117 1170 all phecode
695 Erythematous conditions Dermatologic 1.02 0.981 – 1.07 0.284 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 0.957 0.79 – 1.16 0.654 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 1.08 0.904 – 1.28 0.405 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 1.01 0.774 – 1.32 0.946 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.11 0.876 – 1.41 0.387 73 727 all phecode
695.3 Rosacea Dermatologic 1.03 0.92 – 1.16 0.586 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.01 0.911 – 1.11 0.905 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.1 0.926 – 1.32 0.272 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 0.973 0.872 – 1.08 0.617 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 0.994 0.923 – 1.07 0.878 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 1.07 0.942 – 1.22 0.286 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 0.995 0.791 – 1.25 0.965 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.04 0.946 – 1.14 0.418 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 1.02 0.976 – 1.06 0.403 2252 22509 all phecode
696.4 Psoriasis Dermatologic 1.02 0.975 – 1.06 0.409 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.04 0.987 – 1.09 0.147 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 0.966 0.895 – 1.04 0.384 706 7052 all phecode
697 Sarcoidosis Dermatologic 1.02 0.933 – 1.11 0.664 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 1.08 1 – 1.16 0.0376 782 7814 all phecode
700 Corns and callosities Dermatologic 0.904 0.803 – 1.02 0.0949 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.03 1 – 1.06 0.0404 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 1.04 0.831 – 1.3 0.739 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.04 0.997 – 1.08 0.0713 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.2 0.914 – 1.57 0.191 61 610 all phecode
701.4 Keloid scar Dermatologic 1.19 1.04 – 1.37 0.013 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 0.972 0.882 – 1.07 0.568 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 0.979 0.795 – 1.21 0.842 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.01 0.985 – 1.04 0.363 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 1.03 0.99 – 1.07 0.141 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 0.995 0.959 – 1.03 0.787 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 1.07 0.956 – 1.19 0.249 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 0.992 0.928 – 1.06 0.804 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 0.987 0.959 – 1.02 0.365 5267 52727 all phecode
704.1 Alopecia Dermatologic 1.08 0.911 – 1.29 0.36 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.973 0.778 – 1.22 0.808 76 759 all phecode
705 Disorders of sweat glands Dermatologic 1.01 0.88 – 1.16 0.897 228 2287 all phecode
705.3 Hidradenitis Dermatologic 1.03 0.887 – 1.19 0.701 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 1.1 1.01 – 1.2 0.0231 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 1 0.982 – 1.03 0.682 8317 83195 all phecode
706.1 Acne Dermatologic 1.16 0.922 – 1.47 0.202 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 1 0.982 – 1.03 0.721 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 0.988 0.944 – 1.03 0.616 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 1.02 0.95 – 1.09 0.643 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 1.01 0.976 – 1.05 0.554 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 0.888 0.811 – 0.972 0.00969 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 0.939 0.801 – 1.1 0.436 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.09 0.85 – 1.39 0.502 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.03 0.989 – 1.07 0.153 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.11 1.02 – 1.21 0.0146 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 1.1 1.01 – 1.2 0.027 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.03 0.887 – 1.19 0.723 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.08 0.974 – 1.2 0.148 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.01 0.914 – 1.12 0.832 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.02 0.912 – 1.15 0.698 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 0.88 0.698 – 1.11 0.278 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.03 0.868 – 1.22 0.74 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.09 0.846 – 1.4 0.511 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.01 0.983 – 1.04 0.405 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.01 0.978 – 1.04 0.562 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.989 0.941 – 1.04 0.67 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.96 0.793 – 1.16 0.676 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.971 0.895 – 1.05 0.484 618 6177 all phecode
716 Other arthropathies Musculoskeletal 1 0.99 – 1.01 0.863 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.03 0.993 – 1.06 0.12 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.988 0.972 – 1 0.166 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 0.999 0.988 – 1.01 0.844 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.02 0.956 – 1.08 0.62 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 1.02 0.983 – 1.05 0.326 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1.02 0.995 – 1.04 0.129 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.03 1 – 1.06 0.0352 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1 0.868 – 1.16 0.948 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 0.986 0.885 – 1.1 0.794 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 1.01 0.99 – 1.03 0.302 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.938 0.857 – 1.03 0.166 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.988 0.95 – 1.03 0.53 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.24 0.978 – 1.58 0.0747 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.996 0.966 – 1.03 0.803 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 1.06 0.97 – 1.16 0.194 517 5173 all phecode
723.1 Torticollis Musculoskeletal 1.05 0.867 – 1.28 0.602 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.03 0.984 – 1.08 0.204 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.05 0.943 – 1.16 0.394 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 1.06 0.952 – 1.17 0.303 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 0.877 0.685 – 1.12 0.296 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.02 0.969 – 1.07 0.44 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.01 0.998 – 1.03 0.0903 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 1.02 0.997 – 1.04 0.0978 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 0.992 0.889 – 1.11 0.881 334 3336 all phecode
726.3 Bursitis Musculoskeletal 0.982 0.915 – 1.05 0.612 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.989 0.966 – 1.01 0.382 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.988 0.95 – 1.03 0.546 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 1.12 0.918 – 1.37 0.264 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.979 0.944 – 1.02 0.267 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 1.01 0.925 – 1.1 0.854 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.996 0.893 – 1.11 0.937 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.01 0.855 – 1.2 0.882 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.03 0.992 – 1.06 0.14 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.01 0.918 – 1.12 0.792 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 1.03 0.992 – 1.06 0.143 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.03 0.992 – 1.06 0.13 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 0.996 0.97 – 1.02 0.771 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.01 0.942 – 1.07 0.854 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 0.899 0.739 – 1.09 0.289 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.04 0.927 – 1.18 0.477 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.05 0.925 – 1.18 0.477 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 1.04 0.948 – 1.15 0.392 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.05 0.912 – 1.21 0.491 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.985 0.754 – 1.29 0.909 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.01 0.962 – 1.06 0.681 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 1.07 0.951 – 1.2 0.269 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.932 0.854 – 1.02 0.116 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 1 0.841 – 1.2 0.973 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.98 0.923 – 1.04 0.497 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 0.909 0.755 – 1.1 0.318 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 1.01 0.984 – 1.03 0.629 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 0.982 0.844 – 1.14 0.816 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 0.999 0.971 – 1.03 0.954 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.987 0.942 – 1.03 0.582 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 1.03 0.976 – 1.08 0.297 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1 0.976 – 1.03 0.97 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 1.01 0.96 – 1.06 0.689 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.02 0.895 – 1.16 0.769 248 2476 all phecode
737 Curvature of spine Musculoskeletal 0.991 0.932 – 1.05 0.779 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.981 0.921 – 1.04 0.542 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.973 0.928 – 1.02 0.254 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.966 0.916 – 1.02 0.208 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 1.05 0.959 – 1.16 0.277 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 0.997 0.985 – 1.01 0.638 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.992 0.976 – 1.01 0.298 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.995 0.974 – 1.02 0.643 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.09 0.969 – 1.22 0.157 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.03 0.951 – 1.13 0.428 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.01 0.993 – 1.03 0.209 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.983 0.95 – 1.02 0.337 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 0.898 0.734 – 1.1 0.301 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 0.989 0.911 – 1.07 0.786 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 0.909 0.77 – 1.07 0.262 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 0.989 0.937 – 1.04 0.696 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 0.976 0.806 – 1.18 0.802 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 0.807 0.618 – 1.05 0.113 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.976 0.939 – 1.01 0.22 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 1.06 0.947 – 1.19 0.312 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.901 0.73 – 1.11 0.335 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 0.924 0.843 – 1.01 0.0951 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 0.971 0.927 – 1.02 0.205 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.02 0.995 – 1.04 0.119 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 1.01 0.987 – 1.04 0.353 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 1.03 0.998 – 1.05 0.066 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1 0.915 – 1.09 0.99 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 0.987 0.901 – 1.08 0.773 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.1 1.02 – 1.18 0.0116 815 8144 all phecode
745 Pain in joint Musculoskeletal 0.998 0.975 – 1.02 0.877 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.964 0.927 – 1 0.0667 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.965 0.927 – 1 0.0787 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.918 0.843 – 0.999 0.0476 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.953 0.834 – 1.09 0.477 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.969 0.924 – 1.02 0.206 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.926 0.788 – 1.09 0.348 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.996 0.753 – 1.32 0.977 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.04 0.93 – 1.17 0.469 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 1.02 0.939 – 1.1 0.698 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.994 0.886 – 1.12 0.918 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.02 0.881 – 1.19 0.774 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.04 0.933 – 1.15 0.5 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.03 0.899 – 1.17 0.702 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.984 0.817 – 1.18 0.862 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.02 0.969 – 1.08 0.434 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.02 0.943 – 1.1 0.632 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.04 0.947 – 1.15 0.403 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.973 0.846 – 1.12 0.701 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.03 0.955 – 1.1 0.487 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 1.1 0.997 – 1.22 0.0566 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.972 0.869 – 1.09 0.618 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.16 1.04 – 1.29 0.00974 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 1.16 1.02 – 1.31 0.0224 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 1.15 0.998 – 1.32 0.0535 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.11 0.882 – 1.39 0.38 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.896 0.747 – 1.08 0.241 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.981 0.769 – 1.25 0.874 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.04 0.85 – 1.28 0.681 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.918 0.83 – 1.02 0.099 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.966 0.836 – 1.12 0.641 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.891 0.757 – 1.05 0.168 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.89 0.732 – 1.08 0.241 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.943 0.865 – 1.03 0.185 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.911 0.727 – 1.14 0.422 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.955 0.863 – 1.06 0.366 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.987 0.839 – 1.16 0.878 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.14 0.878 – 1.47 0.331 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.02 0.893 – 1.17 0.743 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.886 0.724 – 1.08 0.242 96 959 all phecode
760 Back pain Symptoms 1.02 0.997 – 1.04 0.0915 11126 111353 all phecode
761 Cervicalgia Symptoms 0.982 0.935 – 1.03 0.466 1791 17901 all phecode
764 Sciatica Symptoms 1.01 0.97 – 1.05 0.596 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.02 0.958 – 1.08 0.558 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 1.01 0.934 – 1.1 0.752 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.989 0.922 – 1.06 0.75 870 8687 all phecode
771.1 Swelling of limb Symptoms 0.995 0.966 – 1.03 0.761 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 0.968 0.893 – 1.05 0.425 659 6581 all phecode
773 Pain in limb Symptoms 1.02 0.99 – 1.04 0.221 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 0.966 0.823 – 1.13 0.666 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.01 0.963 – 1.06 0.686 1870 18715 all phecode
782.3 Edema Symptoms 1.02 0.972 – 1.08 0.386 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 1.06 0.909 – 1.24 0.441 175 1748 all phecode
783 Fever of unknown origin Symptoms 1.02 0.991 – 1.06 0.164 3911 39105 all phecode
785 Abdominal pain Symptoms 1.02 1.01 – 1.03 0.000832 40080 301686 all phecode
788 Syncope and collapse Symptoms 0.999 0.978 – 1.02 0.925 9069 90813 all phecode
789 Nausea and vomiting Symptoms 1.03 1.01 – 1.05 0.00223 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 0.97 0.819 – 1.15 0.724 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 1.08 0.86 – 1.35 0.518 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 0.986 0.961 – 1.01 0.283 6357 63635 all phecode
791 Gangrene Symptoms 1.02 0.936 – 1.11 0.631 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.977 0.798 – 1.2 0.825 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.999 0.844 – 1.18 0.995 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.03 0.949 – 1.13 0.445 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1 0.834 – 1.21 0.971 120 1198 all phecode
797 Shock Symptoms 1.14 0.967 – 1.34 0.12 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 1.06 0.867 – 1.3 0.562 102 1020 all phecode
798 Malaise and fatigue Symptoms 1 0.969 – 1.04 0.849 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 1.04 0.957 – 1.13 0.354 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 0.982 0.958 – 1.01 0.143 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.953 0.908 – 1 0.0522 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.949 0.812 – 1.11 0.513 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.01 0.967 – 1.06 0.659 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 0.996 0.925 – 1.07 0.906 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.984 0.942 – 1.03 0.479 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 0.999 0.953 – 1.05 0.971 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.999 0.925 – 1.08 0.975 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 1.02 0.995 – 1.04 0.117 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 0.997 0.948 – 1.05 0.907 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.01 0.979 – 1.04 0.596 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.05 0.991 – 1.1 0.105 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.972 0.938 – 1.01 0.113 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.984 0.931 – 1.04 0.584 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 1.01 0.937 – 1.09 0.818 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.963 0.909 – 1.02 0.196 1300 12998 all phecode
817 Concussion Injuries & Poisonings 0.937 0.823 – 1.07 0.325 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.95 0.868 – 1.04 0.268 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.02 0.978 – 1.06 0.404 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 1.02 0.969 – 1.07 0.483 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 0.968 0.925 – 1.01 0.159 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 0.999 0.983 – 1.02 0.924 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.08 0.989 – 1.18 0.0854 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 0.963 0.876 – 1.06 0.443 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.01 0.985 – 1.04 0.372 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.97 0.824 – 1.14 0.712 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 0.942 0.86 – 1.03 0.2 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.98 0.934 – 1.03 0.419 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.994 0.937 – 1.05 0.835 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.942 0.908 – 0.977 0.00133 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.04 1.01 – 1.08 0.0232 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 0.951 0.751 – 1.21 0.68 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.01 0.977 – 1.05 0.524 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.996 0.882 – 1.12 0.944 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.943 0.817 – 1.09 0.422 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.02 0.983 – 1.06 0.269 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.08 0.94 – 1.24 0.275 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 1.01 0.794 – 1.29 0.911 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 0.981 0.95 – 1.01 0.247 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.05 0.8 – 1.37 0.739 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.08 0.876 – 1.32 0.482 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.989 0.85 – 1.15 0.889 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 0.97 0.881 – 1.07 0.528 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 1.06 0.931 – 1.22 0.357 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.04 0.893 – 1.22 0.589 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.08 0.917 – 1.27 0.362 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 0.975 0.921 – 1.03 0.393 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.01 0.98 – 1.04 0.508 4260 42663 all phecode
916 Contusion Injuries & Poisonings 0.973 0.921 – 1.03 0.321 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.919 0.787 – 1.07 0.282 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.989 0.891 – 1.1 0.842 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.961 0.844 – 1.09 0.548 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.971 0.929 – 1.02 0.204 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.09 0.95 – 1.24 0.224 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.05 0.86 – 1.28 0.642 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.03 0.946 – 1.13 0.469 550 5509 all phecode
947 Urticaria Injuries & Poisonings 0.948 0.855 – 1.05 0.318 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 0.989 0.892 – 1.1 0.835 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.947 0.857 – 1.05 0.282 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.05 0.928 – 1.19 0.436 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.968 0.881 – 1.06 0.494 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 0.969 0.74 – 1.27 0.821 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.05 0.828 – 1.33 0.687 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.02 1.01 – 1.04 0.00341 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.02 1.01 – 1.04 0.0078 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 0.956 0.866 – 1.06 0.373 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.03 0.962 – 1.11 0.379 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.979 0.88 – 1.09 0.69 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 0.984 0.883 – 1.1 0.769 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.16 1.01 – 1.33 0.0299 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.874 0.776 – 0.984 0.026 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.891 0.791 – 1 0.0577 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1 0.977 – 1.03 0.81 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.973 0.916 – 1.03 0.379 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.927 0.844 – 1.02 0.113 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.11 1 – 1.23 0.042 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.977 0.893 – 1.07 0.62 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.03 0.945 – 1.12 0.509 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 0.997 0.952 – 1.04 0.886 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.996 0.859 – 1.16 0.958 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.09 0.967 – 1.23 0.157 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.07 0.862 – 1.34 0.527 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.05 0.858 – 1.28 0.649 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.95 0.773 – 1.17 0.624 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.934 0.726 – 1.2 0.596 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.05 0.796 – 1.38 0.743 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.05 0.919 – 1.2 0.474 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.06 0.984 – 1.15 0.118 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.938 0.814 – 1.08 0.38 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.08 0.828 – 1.4 0.585 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.05 0.862 – 1.28 0.632 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.991 0.815 – 1.2 0.927 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.03 0.831 – 1.29 0.759 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.11 1.07 – 1.15 7.47e-08 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.05 1.01 – 1.09 0.0133 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 1.05 1.01 – 1.09 0.0133 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 1.01 0.99 – 1.04 0.278 8379 85301 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 0.995 0.956 – 1.04 0.804 2590 26211 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.975 0.898 – 1.06 0.558 601 6297 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.06 0.983 – 1.13 0.138 811 8331 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.38 1.05 – 1.82 0.0215 54 542 exclusion phecode
010 Tuberculosis Infectious Diseases 1 0.85 – 1.18 0.989 158 1619 exclusion phecode
038 Septicemia Infectious Diseases 0.993 0.959 – 1.03 0.665 3636 40570 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 0.974 0.905 – 1.05 0.47 806 8283 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 0.91 0.827 – 1 0.0504 469 4877 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1 0.982 – 1.02 0.878 11325 116648 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 0.99 0.953 – 1.03 0.599 2860 30495 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 0.958 0.91 – 1.01 0.102 1576 16002 exclusion phecode
041.4 E. coli Infectious Diseases 0.987 0.948 – 1.03 0.523 2565 26190 exclusion phecode
053 Herpes zoster Infectious Diseases 1.06 0.956 – 1.18 0.269 388 3985 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.04 0.832 – 1.29 0.755 91 914 exclusion phecode
054 Herpes simplex Infectious Diseases 0.878 0.76 – 1.01 0.0774 195 2043 exclusion phecode
070 Viral hepatitis Infectious Diseases 0.934 0.857 – 1.02 0.121 575 5772 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.01 0.78 – 1.3 0.969 64 665 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.878 0.734 – 1.05 0.157 129 1306 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 0.917 0.803 – 1.05 0.201 252 2515 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.04 0.918 – 1.18 0.52 263 2639 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 0.997 0.902 – 1.1 0.953 411 4155 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.995 0.837 – 1.18 0.957 147 1465 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.996 0.823 – 1.21 0.971 117 1168 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.99 0.927 – 1.06 0.762 964 9684 exclusion phecode
079 Viral infection Infectious Diseases 1.01 0.97 – 1.05 0.653 2646 26769 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.973 0.753 – 1.26 0.837 62 621 exclusion phecode
080 Postoperative infection Infectious Diseases 1.01 0.98 – 1.05 0.46 4013 43412 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 0.966 0.925 – 1.01 0.123 2238 24034 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.14 0.892 – 1.46 0.296 67 692 exclusion phecode
1000 Burns Injuries & Poisonings 0.963 0.885 – 1.05 0.386 565 5660 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 0.971 0.915 – 1.03 0.343 1164 11686 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1 0.973 – 1.03 0.966 5240 52778 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 0.916 0.813 – 1.03 0.146 292 2920 exclusion phecode
1005 Other symptoms Injuries & Poisonings 0.97 0.917 – 1.03 0.303 1318 13963 exclusion phecode
1006 Crushing injury Injuries & Poisonings 1.02 0.899 – 1.16 0.73 256 2525 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 1.1 0.959 – 1.26 0.175 252 2521 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.01 0.944 – 1.08 0.814 993 9977 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 1.01 0.987 – 1.03 0.421 8273 82852 exclusion phecode
1010 Other tests Injuries & Poisonings 0.994 0.968 – 1.02 0.684 5636 57417 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.983 0.962 – 1.01 0.141 8521 88559 exclusion phecode
1012 Late effect Injuries & Poisonings 1.05 0.865 – 1.28 0.609 103 1023 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.04 0.926 – 1.17 0.495 300 3081 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.1 0.854 – 1.41 0.465 66 649 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 0.986 0.954 – 1.02 0.384 3947 40919 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 0.996 0.979 – 1.01 0.628 15111 153823 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1 0.886 – 1.13 0.989 274 2751 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.977 0.863 – 1.11 0.709 268 2689 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.77 0.604 – 0.983 0.0356 73 736 exclusion phecode
110.12 Althete's foot Infectious Diseases 0.916 0.771 – 1.09 0.317 139 1386 exclusion phecode
112 Candidiasis Infectious Diseases 0.946 0.903 – 0.991 0.0203 1944 20482 exclusion phecode
117 Mycoses Infectious Diseases 0.97 0.851 – 1.1 0.645 255 2636 exclusion phecode
117.4 Aspergillosis Infectious Diseases 0.958 0.811 – 1.13 0.616 155 1600 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.953 0.765 – 1.19 0.671 78 787 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 0.802 0.635 – 1.01 0.0646 69 667 exclusion phecode
134 Helminthiases Infectious Diseases 1.24 1.03 – 1.5 0.0249 122 1218 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.19 0.973 – 1.47 0.0892 101 1019 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.11 0.962 – 1.28 0.151 197 1983 exclusion phecode
145 Cancer of mouth Neoplasms 1.02 0.939 – 1.11 0.649 612 6264 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.06 0.945 – 1.19 0.311 299 3043 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.953 0.779 – 1.17 0.644 100 1016 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.23 0.936 – 1.61 0.137 51 531 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.05 0.962 – 1.14 0.298 618 6235 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.03 0.902 – 1.17 0.689 246 2476 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.17 1.03 – 1.33 0.0142 263 2610 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 0.775 0.589 – 1.02 0.0703 51 549 exclusion phecode
150 Cancer of esophagus Neoplasms 1.05 0.976 – 1.14 0.184 731 7507 exclusion phecode
151 Cancer of stomach Neoplasms 1.08 0.985 – 1.18 0.104 546 5582 exclusion phecode
153 Colorectal cancer Neoplasms 1.03 0.998 – 1.06 0.0626 4395 44434 exclusion phecode
153.2 Colon cancer Neoplasms 1.04 1.01 – 1.08 0.0228 2968 30114 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.01 0.965 – 1.06 0.68 2082 21023 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.993 0.897 – 1.1 0.891 390 3880 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.9 0.766 – 1.06 0.197 155 1545 exclusion phecode
157 Pancreatic cancer Neoplasms 0.964 0.888 – 1.05 0.374 634 6387 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.02 0.953 – 1.09 0.608 1014 10297 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.04 1.01 – 1.07 0.013 5260 53904 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.896 0.771 – 1.04 0.149 181 1851 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.895 0.771 – 1.04 0.144 196 1964 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.14 0.983 – 1.33 0.0826 183 1825 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.998 0.755 – 1.32 0.991 53 582 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.02 0.981 – 1.06 0.306 2621 27408 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.02 0.976 – 1.07 0.369 2065 21597 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 0.993 0.894 – 1.1 0.894 399 4223 exclusion phecode
170.1 Bone cancer Neoplasms 0.99 0.821 – 1.19 0.912 121 1271 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1.02 0.901 – 1.15 0.789 301 3194 exclusion phecode
172 Skin cancer Neoplasms 0.999 0.981 – 1.02 0.912 12923 130528 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.04 0.995 – 1.08 0.0832 2570 25813 exclusion phecode
172.11 Melanomas of skin Neoplasms 1.04 0.999 – 1.08 0.0563 2599 26116 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.997 0.977 – 1.02 0.763 10529 106496 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 1.01 0.932 – 1.09 0.811 634 6438 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.904 0.777 – 1.05 0.195 173 1759 exclusion phecode
175 Acquired absence of breast Neoplasms 1.09 0.856 – 1.38 0.495 63 24010 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 0.984 0.941 – 1.03 0.482 2050 21747 exclusion phecode
180.1 Cervical cancer Neoplasms 1.03 0.902 – 1.17 0.693 251 2720 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.981 0.937 – 1.03 0.408 1960 20784 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 1.05 0.984 – 1.11 0.147 1123 12836 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.04 0.978 – 1.1 0.225 1256 13772 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.04 0.973 – 1.12 0.232 868 9667 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.05 0.974 – 1.12 0.215 842 9387 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.06 0.939 – 1.19 0.358 286 3049 exclusion phecode
185 Cancer of prostate Neoplasms 0.985 0.959 – 1.01 0.25 5954 58768 exclusion phecode
187 Cancer of other male genital organs Neoplasms 0.981 0.891 – 1.08 0.689 448 4485 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.769 0.6 – 0.986 0.0382 70 699 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 1.01 0.892 – 1.14 0.908 287 2868 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.967 0.795 – 1.18 0.74 109 1098 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.999 0.967 – 1.03 0.95 4020 40759 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.06 0.996 – 1.13 0.066 1034 10461 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.06 0.998 – 1.14 0.0593 996 10080 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.1 0.847 – 1.42 0.483 63 646 exclusion phecode
189.2 Cancer of bladder Neoplasms 0.976 0.936 – 1.02 0.273 2339 23695 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.99 0.946 – 1.04 0.648 2076 21095 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.922 0.78 – 1.09 0.337 140 1419 exclusion phecode
190 Cancer of eye Neoplasms 1.04 0.894 – 1.22 0.583 169 1707 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.02 0.939 – 1.11 0.651 658 6688 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.983 0.899 – 1.08 0.713 542 5503 exclusion phecode
191.11 Cancer of brain Neoplasms 0.991 0.903 – 1.09 0.841 504 5095 exclusion phecode
193 Thyroid cancer Neoplasms 0.912 0.813 – 1.02 0.117 318 3327 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.01 0.811 – 1.26 0.933 88 921 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.01 0.997 – 1.03 0.104 15439 162081 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.02 0.998 – 1.03 0.0762 14863 156272 exclusion phecode
197 Chemotherapy Neoplasms 1.01 0.991 – 1.02 0.42 17657 207907 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.04 1.01 – 1.06 0.00504 6667 93092 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.03 0.989 – 1.06 0.178 3078 52189 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.06 1.01 – 1.11 0.0179 1777 22192 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.05 0.991 – 1.11 0.1 1354 15054 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.07 1.03 – 1.12 0.00115 2186 26106 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.01 0.932 – 1.1 0.801 641 8296 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 0.97 0.921 – 1.02 0.247 1547 21152 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.973 0.824 – 1.15 0.749 149 1849 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 0.983 0.929 – 1.04 0.548 1321 14033 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.12 0.904 – 1.38 0.302 89 926 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.03 0.966 – 1.1 0.359 961 9626 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.01 0.91 – 1.12 0.826 376 3804 exclusion phecode
201 Hodgkin's disease Neoplasms 0.992 0.871 – 1.13 0.902 250 2530 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.987 0.944 – 1.03 0.565 2162 22008 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.991 0.944 – 1.04 0.731 1743 17502 exclusion phecode
202.21 Nodular lymphoma Neoplasms 0.973 0.873 – 1.08 0.619 354 3530 exclusion phecode
202.24 Large cell lymphoma Neoplasms 0.952 0.872 – 1.04 0.273 566 5631 exclusion phecode
204 Leukemia Neoplasms 1 0.952 – 1.05 0.937 1597 16180 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1 0.919 – 1.09 0.958 555 5648 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.08 0.814 – 1.43 0.596 52 549 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.997 0.909 – 1.09 0.949 489 4957 exclusion phecode
204.2 Myeloid leukemia Neoplasms 0.919 0.835 – 1.01 0.0818 444 4485 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.861 0.768 – 0.966 0.011 316 3196 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.07 0.908 – 1.27 0.41 139 1394 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.07 0.978 – 1.17 0.145 539 5406 exclusion phecode
208 Benign neoplasm of colon Neoplasms 0.986 0.971 – 1 0.0571 19228 186240 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.955 0.893 – 1.02 0.178 936 9450 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.987 0.959 – 1.02 0.373 5006 50361 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.04 0.931 – 1.17 0.465 338 3385 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.872 0.777 – 0.979 0.0206 300 3096 exclusion phecode
214 Lipoma Neoplasms 1.01 0.985 – 1.04 0.383 5986 60612 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.01 0.981 – 1.04 0.449 4386 44453 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.02 0.958 – 1.09 0.532 1046 10650 exclusion phecode
216 Benign neoplasm of skin Neoplasms 1.02 0.996 – 1.05 0.0944 7309 73983 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.01 0.932 – 1.1 0.76 602 6107 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 1.03 0.942 – 1.12 0.543 566 5742 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 1.01 0.992 – 1.03 0.234 9300 94888 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 1.02 0.998 – 1.04 0.0694 9500 96859 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.876 0.781 – 0.982 0.0236 327 3355 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.982 0.929 – 1.04 0.535 1338 14483 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 1 0.867 – 1.16 0.981 198 2196 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 1.04 0.884 – 1.22 0.649 159 1600 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.946 0.805 – 1.11 0.505 166 1683 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.92 0.763 – 1.11 0.381 124 1249 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.05 0.815 – 1.34 0.728 65 656 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.05 0.98 – 1.13 0.155 778 7835 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.05 0.975 – 1.13 0.198 739 7446 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.974 0.739 – 1.28 0.853 56 563 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1 0.879 – 1.15 0.95 249 2522 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.997 0.928 – 1.07 0.928 818 8332 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.05 0.902 – 1.23 0.521 179 1810 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.85 0.759 – 0.952 0.00483 343 3542 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.13 1.01 – 1.27 0.0372 301 3042 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.965 0.916 – 1.02 0.184 1537 15454 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.02 0.973 – 1.06 0.474 2266 22955 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1 0.919 – 1.09 0.949 554 5720 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.96 0.9 – 1.02 0.208 1033 10551 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.959 0.869 – 1.06 0.395 442 4497 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.96 0.885 – 1.04 0.328 630 6447 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.983 0.935 – 1.03 0.494 1705 17654 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 1.01 0.914 – 1.12 0.853 424 4357 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.1 0.879 – 1.37 0.408 83 865 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.904 0.758 – 1.08 0.266 129 1312 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.01 0.997 – 1.03 0.111 13520 137647 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.04 0.975 – 1.11 0.23 987 10500 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.983 0.796 – 1.21 0.875 98 953 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.02 0.999 – 1.04 0.0713 12915 131813 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.975 0.861 – 1.1 0.689 273 2708 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.02 0.886 – 1.18 0.779 208 2042 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.983 0.851 – 1.13 0.81 202 1962 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 0.933 0.838 – 1.04 0.208 365 3773 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.01 0.993 – 1.02 0.315 19064 181091 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.05 1.01 – 1.09 0.0115 2665 26910 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.971 0.849 – 1.11 0.664 228 2327 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.19 0.942 – 1.5 0.144 72 756 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.02 0.932 – 1.12 0.635 455 4628 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.15 0.979 – 1.35 0.0881 153 1581 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1 0.986 – 1.02 0.84 17165 165745 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.01 0.819 – 1.24 0.932 99 1025 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.15 0.996 – 1.33 0.0568 198 1974 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.02 0.952 – 1.09 0.622 967 9690 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.07 0.977 – 1.18 0.139 490 4956 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.01 0.931 – 1.09 0.845 654 6651 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.975 0.86 – 1.11 0.693 257 2600 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.05 0.944 – 1.16 0.392 399 4066 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.959 0.804 – 1.14 0.64 128 1271 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.09 0.971 – 1.21 0.148 342 3436 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.02 0.966 – 1.08 0.439 1298 13037 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 0.99 0.925 – 1.06 0.771 907 9125 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.983 0.915 – 1.06 0.642 812 8327 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.975 0.904 – 1.05 0.513 727 7455 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.04 0.878 – 1.24 0.641 134 1361 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.976 0.9 – 1.06 0.56 656 6614 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.928 0.796 – 1.08 0.336 179 1802 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.956 0.775 – 1.18 0.678 90 908 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.01 0.888 – 1.15 0.872 255 2563 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.922 0.744 – 1.14 0.459 88 887 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.922 0.778 – 1.09 0.345 151 1519 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.991 0.913 – 1.08 0.838 615 6134 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1 0.865 – 1.17 0.954 173 1726 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.972 0.802 – 1.18 0.775 98 980 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.06 0.836 – 1.34 0.64 74 742 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.01 0.902 – 1.13 0.889 351 3479 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.02 0.911 – 1.14 0.759 350 3469 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 1.04 0.912 – 1.19 0.533 230 2316 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.06 0.916 – 1.22 0.441 201 2023 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1.05 0.894 – 1.23 0.553 159 1619 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.06 0.903 – 1.25 0.455 151 1538 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1 0.815 – 1.23 0.977 101 984 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.862 0.725 – 1.02 0.0917 139 1442 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.989 0.857 – 1.14 0.883 192 1960 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1 0.934 – 1.08 0.906 800 8034 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 0.942 0.886 – 1 0.0524 1147 11490 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.936 0.868 – 1.01 0.0881 728 7267 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.943 0.852 – 1.04 0.252 420 4257 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.05 0.828 – 1.34 0.679 72 728 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1 0.874 – 1.15 0.95 224 2303 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.14 1.02 – 1.27 0.023 330 3297 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.05 0.932 – 1.18 0.423 294 2934 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.05 0.925 – 1.2 0.43 252 2518 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.05 0.902 – 1.22 0.529 184 1844 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1.02 0.832 – 1.24 0.874 107 1093 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.05 0.822 – 1.34 0.694 67 667 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.994 0.846 – 1.17 0.946 153 1545 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.978 0.822 – 1.16 0.804 132 1339 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.993 0.982 – 1 0.25 33648 227899 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.993 0.982 – 1 0.236 33579 227676 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.99 0.979 – 1 0.116 31216 220787 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.2 0.925 – 1.56 0.168 58 570 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.966 0.824 – 1.13 0.668 163 1597 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.953 0.828 – 1.1 0.507 207 2042 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.971 0.939 – 1 0.0926 3673 36757 exclusion phecode
274.1 Gout Endocrine/metabolic 0.967 0.932 – 1 0.0698 3137 31394 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.11 0.914 – 1.34 0.3 110 1110 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.971 0.892 – 1.06 0.493 596 5956 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.978 0.895 – 1.07 0.619 543 5425 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.989 0.944 – 1.04 0.632 1956 20480 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.936 0.863 – 1.02 0.112 641 6412 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.03 0.921 – 1.15 0.631 350 3620 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1 0.943 – 1.07 0.91 1079 11629 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.981 0.833 – 1.15 0.814 164 1688 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.01 0.984 – 1.03 0.513 6859 70648 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.03 0.997 – 1.06 0.0747 3862 39623 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.09 0.955 – 1.25 0.198 233 2344 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.01 0.96 – 1.06 0.747 1712 17550 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.06 0.993 – 1.14 0.0769 923 9507 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.04 0.982 – 1.1 0.18 1338 13705 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.02 0.963 – 1.09 0.453 1109 11326 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.04 0.971 – 1.11 0.28 1008 10309 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 0.888 0.733 – 1.08 0.226 109 1093 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 0.968 0.93 – 1.01 0.106 2627 27375 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.1 0.994 – 1.21 0.0665 433 4415 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.03 0.854 – 1.24 0.777 124 1234 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 0.998 0.93 – 1.07 0.967 847 8677 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.06 0.952 – 1.18 0.281 350 3555 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.06 0.928 – 1.22 0.381 226 2240 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.978 0.744 – 1.29 0.872 51 509 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.991 0.971 – 1.01 0.386 10280 104821 exclusion phecode
278.1 Obesity Endocrine/metabolic 0.992 0.972 – 1.01 0.467 10127 103273 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 0.923 0.728 – 1.17 0.508 75 804 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.812 0.628 – 1.05 0.113 65 634 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.902 0.791 – 1.03 0.122 239 2427 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 0.849 0.734 – 0.982 0.027 203 2032 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.857 0.719 – 1.02 0.0828 134 1331 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1 0.878 – 1.15 0.968 244 2455 exclusion phecode
280 Iron deficiency anemias Hematopoietic 0.997 0.974 – 1.02 0.827 7300 73421 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.998 0.974 – 1.02 0.859 7021 70520 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.943 0.854 – 1.04 0.246 427 4366 exclusion phecode
281 Other deficiency anemia Hematopoietic 0.99 0.929 – 1.05 0.757 1061 10695 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 0.984 0.922 – 1.05 0.622 1016 10246 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.01 0.935 – 1.09 0.802 711 7206 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.01 0.86 – 1.18 0.942 170 1710 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 0.846 0.726 – 0.986 0.0326 178 1775 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.22 0.928 – 1.6 0.156 51 525 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.14 0.961 – 1.35 0.135 141 1459 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1 0.808 – 1.25 0.972 82 823 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 0.936 0.781 – 1.12 0.474 131 1329 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.971 0.793 – 1.19 0.776 100 1031 exclusion phecode
284 Aplastic anemia Hematopoietic 0.947 0.857 – 1.05 0.284 411 4245 exclusion phecode
285 Other anemias Hematopoietic 0.996 0.977 – 1.02 0.709 11381 116882 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.951 0.837 – 1.08 0.44 247 2611 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.02 0.941 – 1.11 0.597 605 6738 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.02 0.916 – 1.14 0.689 333 4002 exclusion phecode
286 Coagulation defects Hematopoietic 0.991 0.924 – 1.06 0.799 870 8954 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 1.02 0.921 – 1.12 0.753 434 4452 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.985 0.796 – 1.22 0.892 88 927 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.03 0.908 – 1.16 0.687 280 2851 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.17 0.889 – 1.55 0.259 59 617 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.07 0.852 – 1.33 0.577 85 843 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.98 0.879 – 1.09 0.716 360 3754 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.02 0.964 – 1.07 0.554 1554 16086 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.973 0.813 – 1.17 0.766 125 1247 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.02 0.968 – 1.08 0.432 1458 15123 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.13 1.02 – 1.25 0.0217 401 4058 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.981 0.776 – 1.24 0.872 71 736 exclusion phecode
288 Diseases of white blood cells Hematopoietic 0.993 0.956 – 1.03 0.732 2801 36328 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 0.99 0.948 – 1.03 0.631 2252 30535 exclusion phecode
288.11 Neutropenia Hematopoietic 0.991 0.949 – 1.03 0.663 2259 30604 exclusion phecode
288.3 Eosinophilia Hematopoietic 1.13 0.88 – 1.45 0.341 68 692 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.999 0.929 – 1.07 0.968 825 8353 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.04 0.915 – 1.17 0.57 275 2799 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.03 0.983 – 1.07 0.242 2365 25341 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1.05 0.961 – 1.15 0.263 491 4991 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.03 0.912 – 1.17 0.628 286 2877 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 0.95 0.762 – 1.18 0.645 87 878 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.997 0.951 – 1.05 0.918 1830 18642 exclusion phecode
290.1 Dementias Mental Disorders 0.944 0.883 – 1.01 0.0931 952 9666 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.914 0.825 – 1.01 0.0882 402 4115 exclusion phecode
290.16 Vascular dementia Mental Disorders 1.03 0.893 – 1.19 0.662 198 1958 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.04 0.96 – 1.13 0.332 622 6316 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.21 0.965 – 1.52 0.0981 69 700 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.959 0.892 – 1.03 0.247 806 8148 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.12 0.93 – 1.34 0.237 128 1283 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.02 0.9 – 1.15 0.803 280 2780 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 0.891 0.806 – 0.984 0.023 416 4258 exclusion phecode
292 Neurological disorders Mental Disorders 0.998 0.968 – 1.03 0.914 4419 44886 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.977 0.926 – 1.03 0.398 1436 14647 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.964 0.831 – 1.12 0.63 186 1857 exclusion phecode
292.3 Memory loss Mental Disorders 0.985 0.909 – 1.07 0.704 672 6772 exclusion phecode
292.4 Altered mental status Mental Disorders 1 0.958 – 1.05 0.911 2077 21189 exclusion phecode
292.6 Hallucinations Mental Disorders 1.05 0.933 – 1.19 0.404 297 2975 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.01 0.961 – 1.05 0.813 2052 20446 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.947 0.882 – 1.02 0.13 853 8740 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.05 0.982 – 1.13 0.144 815 8254 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.02 0.933 – 1.11 0.721 556 5660 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.11 0.947 – 1.29 0.2 169 1732 exclusion phecode
295.3 Psychosis Mental Disorders 1.14 0.976 – 1.33 0.0983 167 1664 exclusion phecode
296 Mood disorders Mental Disorders 1 0.983 – 1.02 0.888 11748 119692 exclusion phecode
296.1 Bipolar Mental Disorders 1 0.942 – 1.07 0.902 1015 10309 exclusion phecode
296.2 Depression Mental Disorders 0.999 0.98 – 1.02 0.903 11133 113508 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.03 0.92 – 1.15 0.639 349 3472 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.937 0.834 – 1.05 0.276 299 2966 exclusion phecode
300 Anxiety disorders Mental Disorders 0.993 0.968 – 1.02 0.582 6464 66182 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1 0.974 – 1.03 0.999 5961 61101 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 0.869 0.731 – 1.03 0.111 143 1453 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.06 0.976 – 1.14 0.172 669 6839 exclusion phecode
300.13 Phobia Mental Disorders 0.92 0.839 – 1.01 0.078 464 4821 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.938 0.786 – 1.12 0.477 139 1371 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.02 0.846 – 1.23 0.849 119 1210 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1 0.827 – 1.21 0.981 113 1101 exclusion phecode
301 Personality disorders Mental Disorders 0.981 0.874 – 1.1 0.741 321 3254 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.04 0.856 – 1.26 0.691 113 1147 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 1.01 0.898 – 1.14 0.836 283 2836 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.03 0.931 – 1.13 0.601 450 4516 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 1.04 0.928 – 1.16 0.523 336 3398 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.971 0.807 – 1.17 0.754 119 1183 exclusion phecode
304 Adjustment reaction Mental Disorders 1.1 0.977 – 1.24 0.116 279 2852 exclusion phecode
305.2 Eating disorder Mental Disorders 0.951 0.762 – 1.19 0.653 87 874 exclusion phecode
306 Other mental disorder Mental Disorders 1.01 0.997 – 1.02 0.139 26720 223406 exclusion phecode
306.9 Tension headache Mental Disorders 1.05 0.933 – 1.18 0.412 305 3053 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.842 0.658 – 1.08 0.172 73 761 exclusion phecode
313.3 Autism Mental Disorders 0.834 0.621 – 1.12 0.229 51 535 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.03 0.92 – 1.15 0.619 342 3419 exclusion phecode
315.1 Learning disorder Mental Disorders 1.2 1.02 – 1.41 0.0265 159 1580 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.856 0.68 – 1.08 0.186 87 864 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.01 0.983 – 1.04 0.418 5205 52399 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.01 0.994 – 1.03 0.176 12362 124405 exclusion phecode
317.1 Alcoholism Mental Disorders 1.02 0.999 – 1.04 0.0674 8637 87062 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.03 0.96 – 1.11 0.396 822 8297 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.02 1 – 1.03 0.0243 18601 181065 exclusion phecode
320 Meningitis Neurological 1.05 0.955 – 1.16 0.305 432 4318 exclusion phecode
323 Encephalitis Neurological 1.03 0.918 – 1.15 0.629 327 3323 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 0.926 0.728 – 1.18 0.533 70 714 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 0.999 0.882 – 1.13 0.983 281 2812 exclusion phecode
327 Sleep disorders Neurological 1 0.941 – 1.06 0.981 1142 11427 exclusion phecode
327.3 Sleep apnea Neurological 0.992 0.962 – 1.02 0.625 4346 43580 exclusion phecode
327.4 Insomnia Neurological 1.08 0.913 – 1.27 0.377 159 1612 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.05 0.878 – 1.26 0.592 133 1347 exclusion phecode
331 Other cerebral degenerations Neurological 1.03 0.969 – 1.1 0.331 1088 11048 exclusion phecode
331.1 Hydrocephalus Neurological 1.01 0.916 – 1.11 0.895 471 4812 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.07 0.965 – 1.18 0.203 415 4183 exclusion phecode
332 Parkinson's disease Neurological 1.01 0.946 – 1.07 0.815 1088 10941 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.997 0.93 – 1.07 0.923 867 8601 exclusion phecode
333.1 Essential tremor Neurological 1.07 0.928 – 1.23 0.36 209 2069 exclusion phecode
333.2 Myoclonus Neurological 0.922 0.752 – 1.13 0.434 95 936 exclusion phecode
333.4 Torsion dystonia Neurological 1.05 0.925 – 1.2 0.43 243 2417 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.06 1.01 – 1.12 0.0174 1714 17666 exclusion phecode
334.1 Spinocerebellar disease Neurological 0.966 0.799 – 1.17 0.723 110 1137 exclusion phecode
334.2 Anterior horn cell disease Neurological 1.1 0.964 – 1.26 0.156 236 2370 exclusion phecode
335 Multiple sclerosis Neurological 1 0.947 – 1.06 0.898 1274 12847 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.1 0.968 – 1.25 0.144 256 2584 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.12 0.879 – 1.44 0.353 70 700 exclusion phecode
338 Pain Neurological 1 0.931 – 1.08 0.908 718 7414 exclusion phecode
338.1 Acute pain Neurological 0.977 0.878 – 1.09 0.672 362 3815 exclusion phecode
338.2 Chronic pain Neurological 1.03 0.926 – 1.15 0.583 362 3666 exclusion phecode
339 Other headache syndromes Neurological 1.02 1 – 1.05 0.0446 7463 75424 exclusion phecode
340 Migraine Neurological 1.02 0.976 – 1.06 0.444 2714 27423 exclusion phecode
340.1 Migrain with aura Neurological 1.19 1.03 – 1.38 0.0169 202 2041 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.03 0.899 – 1.17 0.702 244 2464 exclusion phecode
342 Hemiplegia Neurological 0.975 0.924 – 1.03 0.352 1446 14540 exclusion phecode
343 Infantile cerebral palsy Neurological 1.07 0.905 – 1.27 0.425 143 1415 exclusion phecode
344 Other paralytic syndromes Neurological 0.933 0.859 – 1.01 0.0953 632 6437 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.01 0.982 – 1.04 0.47 4840 48885 exclusion phecode
345.1 Epilepsy Neurological 0.982 0.915 – 1.05 0.623 841 8425 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.04 0.945 – 1.15 0.398 428 4271 exclusion phecode
345.12 Partial epilepsy Neurological 0.91 0.805 – 1.03 0.129 267 2686 exclusion phecode
345.3 Convulsions Neurological 0.997 0.954 – 1.04 0.893 2142 21744 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.17 0.979 – 1.4 0.0833 131 1398 exclusion phecode
348 Other conditions of brain Neurological 1.03 0.953 – 1.11 0.493 745 7607 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 0.956 0.839 – 1.09 0.503 251 2586 exclusion phecode
348.4 Cerebral cysts Neurological 0.953 0.796 – 1.14 0.597 128 1308 exclusion phecode
348.7 Coma Neurological 0.95 0.85 – 1.06 0.367 345 3492 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.09 0.955 – 1.24 0.203 239 2449 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 0.917 0.826 – 1.02 0.103 372 3792 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1 0.894 – 1.12 0.99 325 3287 exclusion phecode
350 Abnormal movement Neurological 1.02 0.982 – 1.06 0.282 2536 25904 exclusion phecode
350.1 Abnormal involuntary movements Neurological 0.979 0.914 – 1.05 0.559 845 8588 exclusion phecode
350.2 Abnormality of gait Neurological 1.03 0.977 – 1.08 0.281 1502 15466 exclusion phecode
350.3 Lack of coordination Neurological 1.07 0.961 – 1.19 0.211 353 3531 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.822 0.625 – 1.08 0.162 54 522 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.01 0.992 – 1.03 0.244 11866 119214 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.04 0.985 – 1.1 0.147 1315 13219 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.06 0.96 – 1.17 0.255 445 4471 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.04 0.967 – 1.11 0.31 846 8492 exclusion phecode
353 Nerve root and plexus disorders Neurological 0.969 0.91 – 1.03 0.319 1067 10922 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.92 0.761 – 1.11 0.391 106 1098 exclusion phecode
353.2 Nerve root lesions Neurological 0.845 0.642 – 1.11 0.229 56 546 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.07 0.907 – 1.27 0.413 149 1489 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.02 0.968 – 1.08 0.407 1282 13335 exclusion phecode
358 Myoneural disorders Neurological 1.06 0.915 – 1.22 0.444 202 2047 exclusion phecode
358.1 Myasthenia gravis Neurological 0.996 0.856 – 1.16 0.961 183 1863 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 1.03 0.935 – 1.14 0.532 440 4493 exclusion phecode
359.1 Muscular dystrophies Neurological 1.06 0.874 – 1.28 0.574 119 1185 exclusion phecode
359.2 Myopathy Neurological 0.998 0.892 – 1.12 0.97 337 3474 exclusion phecode
360 Disorders of the globe Sense Organs 0.98 0.875 – 1.1 0.729 325 3255 exclusion phecode
360.2 Progressive myopia Sense Organs 0.983 0.862 – 1.12 0.793 241 2416 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.986 0.951 – 1.02 0.463 3146 31583 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.01 0.951 – 1.06 0.835 1355 13554 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 1.14 0.884 – 1.47 0.309 67 660 exclusion phecode
362 Other retinal disorders Sense Organs 0.998 0.964 – 1.03 0.892 3649 36924 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.981 0.938 – 1.03 0.418 2057 20817 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.981 0.937 – 1.03 0.408 2054 20788 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.08 0.914 – 1.27 0.375 155 1558 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1.2 0.977 – 1.48 0.0821 96 957 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.04 0.965 – 1.11 0.328 814 8244 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 1.16 0.992 – 1.35 0.0629 174 1782 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.883 0.701 – 1.11 0.293 80 787 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.876 0.723 – 1.06 0.179 116 1123 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.12 0.954 – 1.3 0.17 164 1640 exclusion phecode
363.3 Chorioretinal scars Sense Organs 1.11 0.878 – 1.41 0.378 67 673 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.964 0.887 – 1.05 0.378 623 6236 exclusion phecode
364.1 Corneal opacity Sense Organs 1.09 0.872 – 1.37 0.443 87 886 exclusion phecode
364.2 Corneal edema Sense Organs 0.893 0.709 – 1.12 0.336 76 771 exclusion phecode
364.4 Corneal degenerations Sense Organs 0.979 0.846 – 1.13 0.777 199 1952 exclusion phecode
364.41 Keratoconus Sense Organs 0.886 0.71 – 1.11 0.284 86 856 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.941 0.814 – 1.09 0.41 199 2011 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 1.02 0.835 – 1.26 0.818 97 967 exclusion phecode
365 Glaucoma Sense Organs 1.03 0.994 – 1.06 0.117 4223 42542 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 1.01 0.944 – 1.07 0.844 997 9987 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 1 0.938 – 1.07 0.993 992 9927 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.08 0.997 – 1.17 0.0609 662 6688 exclusion phecode
366 Cataract Sense Organs 1 0.986 – 1.02 0.923 19091 162354 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 1.14 0.906 – 1.44 0.259 67 681 exclusion phecode
366.2 Senile cataract Sense Organs 0.997 0.974 – 1.02 0.814 7874 78514 exclusion phecode
366.3 Traumatic cataract Sense Organs 1.06 0.867 – 1.3 0.559 101 1006 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.03 0.986 – 1.07 0.183 2319 23161 exclusion phecode
367.1 Myopia Sense Organs 1.02 0.959 – 1.08 0.573 1202 12023 exclusion phecode
367.2 Astigmatism Sense Organs 1.06 0.91 – 1.24 0.447 179 1815 exclusion phecode
367.8 Hypermetropia Sense Organs 0.898 0.786 – 1.03 0.111 248 2414 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.05 0.973 – 1.14 0.199 695 6950 exclusion phecode
368 Visual disturbances Sense Organs 1 0.965 – 1.04 0.865 2809 28635 exclusion phecode
368.1 Amblyopia Sense Organs 0.996 0.911 – 1.09 0.931 512 5093 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.944 0.874 – 1.02 0.152 691 7085 exclusion phecode
368.3 Anisometropia Sense Organs 0.992 0.84 – 1.17 0.925 145 1493 exclusion phecode
368.4 Visual field defects Sense Organs 1.01 0.9 – 1.13 0.896 323 3242 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.984 0.903 – 1.07 0.723 574 5907 exclusion phecode
369 Infection of the eye Sense Organs 1.03 0.946 – 1.13 0.458 532 5342 exclusion phecode
369.2 Eye infection, viral Sense Organs 1.01 0.843 – 1.21 0.908 119 1199 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 1.01 0.874 – 1.17 0.884 205 2046 exclusion phecode
370 Keratitis Sense Organs 1.06 0.94 – 1.2 0.332 277 2765 exclusion phecode
370.1 Corneal ulcer Sense Organs 1.03 0.87 – 1.23 0.702 136 1366 exclusion phecode
371 Inflammation of the eye Sense Organs 0.996 0.959 – 1.03 0.822 2932 29507 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.01 0.916 – 1.11 0.901 467 4670 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 1 0.958 – 1.04 0.983 2263 22829 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.01 0.94 – 1.09 0.743 731 7347 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.994 0.967 – 1.02 0.684 5466 54729 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.944 0.885 – 1.01 0.0784 1030 10339 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.982 0.935 – 1.03 0.47 1751 17480 exclusion phecode
375 Disorders of lacrimal system Sense Organs 1.01 0.963 – 1.05 0.751 2091 21043 exclusion phecode
375.2 Epiphora Sense Organs 0.986 0.918 – 1.06 0.687 850 8549 exclusion phecode
376 Disorders of the orbit Sense Organs 0.96 0.77 – 1.2 0.717 84 831 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.957 0.855 – 1.07 0.445 342 3486 exclusion phecode
377.1 Optic atrophy Sense Organs 1.04 0.798 – 1.37 0.752 54 557 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.948 0.782 – 1.15 0.59 118 1202 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.962 0.909 – 1.02 0.175 1364 13671 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.951 0.886 – 1.02 0.156 877 8789 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.996 0.864 – 1.15 0.95 208 2091 exclusion phecode
378.5 Paralytic strabismus Sense Organs 0.926 0.814 – 1.05 0.245 264 2674 exclusion phecode
379 Other disorders of eye Sense Organs 0.986 0.952 – 1.02 0.413 3542 35724 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.98 0.926 – 1.04 0.496 1304 13189 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.973 0.926 – 1.02 0.284 1725 17435 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 0.936 0.734 – 1.19 0.592 66 687 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.02 0.919 – 1.13 0.714 385 3906 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.02 0.865 – 1.2 0.827 158 1636 exclusion phecode
380 Disorders of external ear Sense Organs 0.98 0.904 – 1.06 0.628 626 6239 exclusion phecode
380.1 Otitis externa Sense Organs 1.01 0.919 – 1.11 0.852 495 4958 exclusion phecode
380.4 Impacted cerumen Sense Organs 1.06 0.95 – 1.18 0.299 350 3491 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1 0.956 – 1.05 0.987 2071 20775 exclusion phecode
381.1 Otitis media Sense Organs 1.01 0.961 – 1.06 0.708 1704 17086 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.02 0.947 – 1.09 0.643 821 8256 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.931 0.802 – 1.08 0.35 184 1867 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.934 0.794 – 1.1 0.414 164 1654 exclusion phecode
381.9 Otorrhea Sense Organs 1.02 0.899 – 1.16 0.759 270 2721 exclusion phecode
382 Otalgia Sense Organs 1.01 0.9 – 1.14 0.829 285 2967 exclusion phecode
383 Otosclerosis Sense Organs 0.931 0.828 – 1.05 0.235 298 3002 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1 0.946 – 1.06 0.949 1259 12587 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 0.993 0.931 – 1.06 0.831 1004 10104 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.03 0.955 – 1.11 0.464 757 7610 exclusion phecode
385.3 Cholesteatoma Sense Organs 1.07 0.984 – 1.17 0.111 585 5911 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.994 0.869 – 1.14 0.925 236 2332 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.971 0.923 – 1.02 0.263 1660 16731 exclusion phecode
386.1 Meniere's disease Sense Organs 0.99 0.906 – 1.08 0.831 542 5534 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.894 0.803 – 0.995 0.0411 360 3615 exclusion phecode
386.3 Labyrinthitis Sense Organs 0.998 0.924 – 1.08 0.95 741 7417 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.993 0.963 – 1.02 0.671 4374 44351 exclusion phecode
388 Other disorders of ear Sense Organs 1.08 0.937 – 1.25 0.281 195 1949 exclusion phecode
389 Hearing loss Sense Organs 0.997 0.965 – 1.03 0.861 4031 40600 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.989 0.896 – 1.09 0.825 442 4399 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.02 0.929 – 1.13 0.625 440 4341 exclusion phecode
389.4 Tinnitus Sense Organs 1.04 0.951 – 1.14 0.378 498 4996 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1 0.973 – 1.03 0.879 4726 47679 exclusion phecode
394.2 Mitral valve disease Circulatory System 1 0.966 – 1.04 0.857 2882 29085 exclusion phecode
394.3 Aortic valve disease Circulatory System 1 0.948 – 1.07 0.872 1240 12506 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 0.948 0.889 – 1.01 0.102 1020 10246 exclusion phecode
395 Heart valve disorders Circulatory System 1.01 0.976 – 1.04 0.642 4067 41116 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.996 0.958 – 1.04 0.846 2781 28107 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.984 0.868 – 1.12 0.807 268 2708 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.01 0.816 – 1.25 0.929 100 1024 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.06 0.86 – 1.3 0.594 97 946 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.01 0.961 – 1.07 0.604 1448 14596 exclusion phecode
396 Abnormal heart sounds Circulatory System 0.958 0.897 – 1.02 0.195 974 10029 exclusion phecode
401 Hypertension Circulatory System 0.991 0.983 – 1 0.0467 70777 259204 exclusion phecode
401.1 Essential hypertension Circulatory System 0.991 0.982 – 0.999 0.0361 70560 258992 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.02 0.968 – 1.06 0.535 1832 18570 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.09 0.986 – 1.22 0.091 362 3632 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.994 0.942 – 1.05 0.814 1484 15097 exclusion phecode
401.3 Other hypertensive complications Circulatory System 0.966 0.816 – 1.14 0.692 138 1401 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 0.957 0.906 – 1.01 0.117 1415 14377 exclusion phecode
411 Ischemic Heart Disease Circulatory System 0.995 0.983 – 1.01 0.463 30497 204338 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.995 0.967 – 1.02 0.757 5029 50315 exclusion phecode
411.2 Myocardial infarction Circulatory System 1 0.982 – 1.02 0.888 11737 110723 exclusion phecode
411.3 Angina pectoris Circulatory System 1 0.987 – 1.02 0.703 15474 139847 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 0.991 0.976 – 1.01 0.225 19828 151239 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.998 0.922 – 1.08 0.969 681 6839 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.995 0.978 – 1.01 0.534 14926 128684 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.971 0.914 – 1.03 0.331 1193 11937 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 0.971 0.925 – 1.02 0.237 1761 17912 exclusion phecode
414.2 ASCVD Circulatory System 0.848 0.668 – 1.08 0.178 69 710 exclusion phecode
415 Pulmonary heart disease Circulatory System 0.996 0.965 – 1.03 0.81 4201 43500 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.21 0.958 – 1.53 0.109 72 714 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.923 0.848 – 1.01 0.0677 583 5812 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 0.922 0.835 – 1.02 0.106 433 4320 exclusion phecode
416 Cardiomegaly Circulatory System 0.971 0.933 – 1.01 0.147 2604 26175 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.02 1 – 1.03 0.0176 27547 261731 exclusion phecode
418.1 Precordial pain Circulatory System 1.02 0.986 – 1.06 0.246 3424 34403 exclusion phecode
420 Carditis Circulatory System 0.987 0.943 – 1.03 0.579 2013 20517 exclusion phecode
420.1 Myocarditis Circulatory System 0.884 0.734 – 1.06 0.192 125 1241 exclusion phecode
420.2 Pericarditis Circulatory System 1 0.946 – 1.06 0.925 1271 13034 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.01 0.878 – 1.16 0.879 220 2178 exclusion phecode
420.22 Chronic pericarditis Circulatory System 0.988 0.816 – 1.2 0.899 109 1103 exclusion phecode
420.3 Endocarditis Circulatory System 0.964 0.892 – 1.04 0.354 695 7007 exclusion phecode
425 Cardiomyopathy Circulatory System 1 0.948 – 1.07 0.874 1224 12422 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1 0.942 – 1.06 0.996 1191 12079 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.04 0.869 – 1.25 0.66 129 1294 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.992 0.846 – 1.16 0.917 160 1576 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 0.932 0.726 – 1.2 0.582 59 598 exclusion phecode
426 Cardiac conduction disorders Circulatory System 0.991 0.967 – 1.02 0.488 6708 67513 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 0.989 0.945 – 1.04 0.638 2059 20756 exclusion phecode
426.21 First degree AV block Circulatory System 0.979 0.916 – 1.05 0.528 967 9692 exclusion phecode
426.23 Second degree AV block Circulatory System 1.05 0.957 – 1.16 0.284 441 4452 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 0.951 0.872 – 1.04 0.251 567 5744 exclusion phecode
426.25 Other heart block Circulatory System 1.01 0.845 – 1.21 0.914 126 1284 exclusion phecode
426.3 Bundle branch block Circulatory System 1.01 0.974 – 1.05 0.598 3236 32524 exclusion phecode
426.31 Right bundle branch block Circulatory System 1 0.953 – 1.06 0.857 1452 14624 exclusion phecode
426.32 Left bundle branch block Circulatory System 1 0.955 – 1.05 0.888 1691 17005 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.875 0.763 – 1 0.0578 223 2279 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.15 0.887 – 1.48 0.295 57 578 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.987 0.946 – 1.03 0.526 2406 24220 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.99 0.947 – 1.03 0.649 2209 22248 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 0.986 0.972 – 0.999 0.0363 23323 199753 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1 0.969 – 1.04 0.802 3081 31117 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.01 0.969 – 1.06 0.601 2238 22715 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.977 0.913 – 1.05 0.498 921 9222 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 0.98 0.963 – 0.997 0.0204 14182 130160 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.984 0.949 – 1.02 0.391 3124 31519 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.954 0.898 – 1.01 0.124 1157 11660 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.02 0.911 – 1.14 0.753 333 3385 exclusion phecode
427.42 Cardiac arrest Circulatory System 0.954 0.893 – 1.02 0.164 962 9666 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.925 0.864 – 0.99 0.0252 910 9269 exclusion phecode
427.6 Premature beats Circulatory System 1.02 0.93 – 1.11 0.704 517 5209 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1 0.827 – 1.21 0.997 116 1144 exclusion phecode
427.7 Tachycardia NOS Circulatory System 0.997 0.953 – 1.04 0.883 2046 21135 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.983 0.884 – 1.09 0.745 388 3909 exclusion phecode
427.9 Palpitations Circulatory System 1.02 0.988 – 1.06 0.197 3619 36633 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.991 0.963 – 1.02 0.516 5422 54810 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 0.992 0.948 – 1.04 0.732 2044 20589 exclusion phecode
428.2 Heart failure NOS Circulatory System 0.996 0.966 – 1.03 0.816 4315 43620 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 0.999 0.924 – 1.08 0.977 696 6961 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.15 0.897 – 1.47 0.275 61 629 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1 0.917 – 1.1 0.923 512 5079 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1 0.864 – 1.16 0.999 186 1903 exclusion phecode
430 Intracranial hemorrhage Circulatory System 0.997 0.951 – 1.05 0.914 1822 18251 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.988 0.919 – 1.06 0.743 811 8034 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 0.993 0.922 – 1.07 0.859 740 7448 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 0.948 0.836 – 1.08 0.408 256 2607 exclusion phecode
433 Cerebrovascular disease Circulatory System 0.988 0.966 – 1.01 0.282 8468 85012 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.978 0.92 – 1.04 0.462 1156 11533 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 0.973 0.846 – 1.12 0.697 220 2191 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.958 0.928 – 0.989 0.00881 4116 41271 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.942 0.896 – 0.991 0.0209 1630 16369 exclusion phecode
433.3 Cerebral ischemia Circulatory System 0.993 0.955 – 1.03 0.733 2792 28132 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.01 0.963 – 1.05 0.747 2074 20748 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.05 0.947 – 1.17 0.335 370 3768 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.962 0.908 – 1.02 0.185 1236 12427 exclusion phecode
440 Atherosclerosis Circulatory System 1.07 1.01 – 1.13 0.025 1354 13535 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.956 0.787 – 1.16 0.65 111 1105 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.06 0.981 – 1.14 0.151 788 7931 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.17 1.03 – 1.32 0.0125 281 2769 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 0.933 0.858 – 1.01 0.105 580 5919 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.952 0.84 – 1.08 0.445 268 2717 exclusion phecode
442 Other aneurysm Circulatory System 1 0.954 – 1.05 0.978 1854 18693 exclusion phecode
442.1 Aortic aneurysm Circulatory System 0.991 0.939 – 1.05 0.741 1433 14448 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.998 0.934 – 1.07 0.964 921 9268 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.06 0.863 – 1.3 0.577 102 1012 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.912 0.776 – 1.07 0.262 165 1670 exclusion phecode
442.4 Arterial dissection Circulatory System 1.18 0.889 – 1.56 0.254 53 536 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.05 0.903 – 1.21 0.55 195 1970 exclusion phecode
443 Peripheral vascular disease Circulatory System 1 0.971 – 1.04 0.829 3814 38197 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.01 0.949 – 1.08 0.74 1094 10916 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.882 0.795 – 0.979 0.0188 381 3817 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.01 0.974 – 1.04 0.641 3582 35877 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.01 0.966 – 1.05 0.764 2522 25320 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.01 0.942 – 1.08 0.8 898 9082 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.99 0.906 – 1.08 0.828 543 5467 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.04 0.971 – 1.12 0.246 786 7907 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.947 0.817 – 1.1 0.472 186 1826 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.07 0.961 – 1.19 0.217 365 3676 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.07 0.938 – 1.22 0.317 234 2335 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.02 0.959 – 1.08 0.592 1301 13049 exclusion phecode
447.1 Stricture of artery Circulatory System 1.03 0.962 – 1.11 0.385 857 8557 exclusion phecode
448 Disease of capillaries Circulatory System 0.936 0.784 – 1.12 0.468 135 1365 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.06 0.976 – 1.16 0.159 526 6739 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.991 0.958 – 1.02 0.596 3733 38577 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.99 0.956 – 1.03 0.585 3501 35961 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1.04 0.952 – 1.14 0.368 519 5468 exclusion phecode
454 Varicose veins Circulatory System 1.02 1 – 1.04 0.0218 10698 107824 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1.02 1.01 – 1.05 0.0137 10982 110692 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.939 0.863 – 1.02 0.141 593 6151 exclusion phecode
455 Hemorrhoids Circulatory System 0.996 0.983 – 1.01 0.598 22689 227493 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.857 0.73 – 1.01 0.0598 176 1820 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.14 0.929 – 1.4 0.208 94 938 exclusion phecode
458 Hypotension Circulatory System 0.993 0.966 – 1.02 0.637 5469 55972 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.05 0.988 – 1.11 0.12 1279 12991 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 0.85 0.742 – 0.974 0.0195 228 2272 exclusion phecode
458.9 Hypotension NOS Circulatory System 0.983 0.949 – 1.02 0.351 3292 33918 exclusion phecode
459 Other disorders of circulatory system Circulatory System 0.996 0.98 – 1.01 0.65 15433 155978 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 0.943 0.792 – 1.12 0.506 132 1381 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 0.997 0.981 – 1.01 0.732 15281 154653 exclusion phecode
464 Acute sinusitis Respiratory 0.947 0.815 – 1.1 0.481 187 1877 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.01 0.962 – 1.05 0.785 2061 22070 exclusion phecode
465.2 Acute pharyngitis Respiratory 1.03 0.952 – 1.1 0.506 735 8102 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.01 0.864 – 1.19 0.873 159 1594 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.986 0.956 – 1.02 0.359 4558 45576 exclusion phecode
471 Nasal polyps Respiratory 1 0.965 – 1.04 0.979 3227 32267 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.01 0.942 – 1.08 0.824 926 9326 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1 0.964 – 1.05 0.843 2463 24728 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.05 0.853 – 1.28 0.667 103 1009 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.924 0.81 – 1.05 0.237 245 2562 exclusion phecode
473.4 Voice disturbance Respiratory 1.02 0.96 – 1.09 0.47 1038 10425 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 0.983 0.936 – 1.03 0.496 1730 17289 exclusion phecode
474.1 Acute tonsillitis Respiratory 0.958 0.876 – 1.05 0.343 529 5351 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.994 0.935 – 1.06 0.861 1097 10892 exclusion phecode
475 Chronic sinusitis Respiratory 0.993 0.954 – 1.03 0.747 2507 25089 exclusion phecode
476 Allergic rhinitis Respiratory 0.99 0.929 – 1.05 0.758 1016 10228 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1 0.963 – 1.05 0.838 2354 23801 exclusion phecode
478 Throat pain Respiratory 0.942 0.847 – 1.05 0.272 361 3647 exclusion phecode
479 Other upper respiratory disease Respiratory 1.02 0.983 – 1.05 0.363 3960 39639 exclusion phecode
480 Pneumonia Respiratory 1 0.984 – 1.03 0.642 9840 100504 exclusion phecode
480.1 Bacterial pneumonia Respiratory 0.999 0.973 – 1.03 0.937 6295 64486 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 0.998 0.97 – 1.03 0.86 5576 57104 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 0.973 0.782 – 1.21 0.808 87 904 exclusion phecode
480.2 Viral pneumonia Respiratory 0.925 0.718 – 1.19 0.547 69 696 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.08 0.88 – 1.32 0.472 95 965 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.02 0.947 – 1.1 0.626 756 7735 exclusion phecode
481 Influenza Respiratory 0.916 0.815 – 1.03 0.139 315 3184 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.11 0.957 – 1.28 0.17 184 1863 exclusion phecode
495 Asthma Respiratory 0.997 0.984 – 1.01 0.684 24392 241857 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.1 0.964 – 1.25 0.158 240 2423 exclusion phecode
496 Chronic airway obstruction Respiratory 1.02 0.997 – 1.04 0.0988 9951 98445 exclusion phecode
496.1 Emphysema Respiratory 1.01 0.958 – 1.06 0.765 1660 16988 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.1 1.05 – 1.14 3.18e-06 2828 28583 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.09 1.05 – 1.14 2.11e-05 2596 26267 exclusion phecode
496.3 Bronchiectasis Respiratory 1 0.954 – 1.05 0.937 1779 18136 exclusion phecode
497 Bronchitis Respiratory 1.07 0.983 – 1.16 0.118 599 6054 exclusion phecode
500 Lung disease due to external agents Respiratory 1.02 0.92 – 1.13 0.718 395 4038 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.934 0.745 – 1.17 0.558 79 758 exclusion phecode
500.2 Pneumoconiosis Respiratory 1.09 0.956 – 1.24 0.2 241 2398 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.03 0.955 – 1.12 0.406 633 6423 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.02 0.954 – 1.09 0.545 882 8939 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 0.93 0.847 – 1.02 0.129 489 4921 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.983 0.875 – 1.1 0.768 317 3176 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 0.828 0.638 – 1.08 0.157 59 586 exclusion phecode
506 Empyema and pneumothorax Respiratory 0.995 0.935 – 1.06 0.865 1075 11107 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1 0.977 – 1.03 0.81 5996 62505 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.04 0.992 – 1.09 0.103 1897 19342 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.01 0.972 – 1.06 0.537 2493 25256 exclusion phecode
509.1 Respiratory failure Respiratory 1.02 0.972 – 1.07 0.461 1975 20083 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.01 0.966 – 1.07 0.566 1722 17547 exclusion phecode
509.5 Respiratory arrest Respiratory 0.9 0.754 – 1.07 0.241 141 1382 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.957 0.863 – 1.06 0.41 380 3743 exclusion phecode
510 Other diseases of lung Respiratory 1.01 0.933 – 1.09 0.849 703 7327 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.01 0.991 – 1.04 0.259 8526 87384 exclusion phecode
512.1 Wheezing Respiratory 0.88 0.767 – 1.01 0.0674 211 2129 exclusion phecode
512.2 Painful respiration Respiratory 0.906 0.781 – 1.05 0.192 191 1995 exclusion phecode
512.7 Shortness of breath Respiratory 1.03 1 – 1.06 0.0207 5517 56563 exclusion phecode
512.8 Cough Respiratory 0.966 0.929 – 1 0.0837 2706 27660 exclusion phecode
512.9 Other dyspnea Respiratory 0.998 0.931 – 1.07 0.957 879 8878 exclusion phecode
513 Respiratory abnormalities Respiratory 0.94 0.863 – 1.02 0.152 587 5963 exclusion phecode
513.3 Hypoventilation Respiratory 0.679 0.535 – 0.862 0.00148 77 809 exclusion phecode
513.4 Hyperventilation Respiratory 1.05 0.927 – 1.19 0.451 265 2680 exclusion phecode
513.8 Disorders of diaphragm Respiratory 0.898 0.756 – 1.07 0.219 150 1518 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.03 0.986 – 1.07 0.192 2281 23883 exclusion phecode
516 Abnormal sputum Respiratory 0.995 0.951 – 1.04 0.826 2054 20778 exclusion phecode
516.1 Hemoptysis Respiratory 0.989 0.945 – 1.04 0.631 1996 20201 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.01 0.987 – 1.03 0.426 8840 90880 exclusion phecode
519.2 Respiratory complications Respiratory 1.01 0.903 – 1.14 0.806 304 3159 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.02 0.993 – 1.04 0.177 8381 85909 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.962 0.848 – 1.09 0.544 268 2937 exclusion phecode
520 Disorders of tooth development Digestive 1.01 0.963 – 1.06 0.728 1974 19794 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.07 0.811 – 1.42 0.617 51 513 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 1.02 0.976 – 1.06 0.396 2283 22893 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 0.977 0.941 – 1.02 0.242 2894 29405 exclusion phecode
521.1 Dental caries Digestive 0.973 0.937 – 1.01 0.161 2906 29490 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 0.973 0.925 – 1.02 0.278 1690 17178 exclusion phecode
522.5 Periapical abscess Digestive 0.99 0.931 – 1.05 0.738 1120 11356 exclusion phecode
523 Gingival and periodontal diseases Digestive 0.982 0.932 – 1.03 0.479 1611 16293 exclusion phecode
523.1 Gingivitis Digestive 1.01 0.834 – 1.23 0.91 106 1083 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 0.979 0.921 – 1.04 0.505 1120 11302 exclusion phecode
523.31 Acute periodontitis Digestive 0.985 0.909 – 1.07 0.713 642 6469 exclusion phecode
523.32 Chronic periodontitis Digestive 1.01 0.924 – 1.11 0.802 534 5409 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.04 0.926 – 1.17 0.5 324 3208 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.03 0.914 – 1.16 0.618 298 2960 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.999 0.959 – 1.04 0.966 2547 25843 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.863 0.667 – 1.12 0.261 69 682 exclusion phecode
526 Diseases of the jaws Digestive 0.977 0.912 – 1.05 0.505 887 8958 exclusion phecode
526.1 Cysts of the jaws Digestive 0.913 0.815 – 1.02 0.114 323 3199 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.09 0.829 – 1.43 0.544 57 590 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.04 0.91 – 1.19 0.562 229 2306 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.03 0.9 – 1.19 0.645 222 2236 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.976 0.797 – 1.2 0.816 102 1058 exclusion phecode
526.9 Jaw disease NOS Digestive 1.01 0.878 – 1.15 0.937 224 2241 exclusion phecode
527 Diseases of the salivary glands Digestive 0.986 0.911 – 1.07 0.726 671 6715 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.05 0.839 – 1.31 0.674 82 806 exclusion phecode
527.2 Sialoadenitis Digestive 0.989 0.888 – 1.1 0.837 355 3534 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 0.813 0.634 – 1.04 0.102 60 595 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 0.988 0.811 – 1.2 0.903 113 1158 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.991 0.958 – 1.03 0.601 3689 37440 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.01 0.917 – 1.12 0.803 414 4512 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.06 0.951 – 1.18 0.297 345 3746 exclusion phecode
528.12 Oral aphthae Digestive 0.861 0.682 – 1.09 0.21 74 818 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.01 0.861 – 1.18 0.916 170 1738 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.869 0.724 – 1.04 0.132 119 1172 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.971 0.788 – 1.2 0.786 91 908 exclusion phecode
528.5 Diseases of lips Digestive 1.02 0.939 – 1.1 0.674 659 6572 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.01 0.903 – 1.14 0.816 300 2982 exclusion phecode
528.7 Sialolithiasis Digestive 0.971 0.864 – 1.09 0.619 306 3046 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.06 1 – 1.13 0.0492 1184 11911 exclusion phecode
529.1 Glossitis Digestive 1.08 0.961 – 1.22 0.192 290 2890 exclusion phecode
530 Diseases of esophagus Digestive 1.01 0.996 – 1.02 0.198 32183 270320 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.01 0.998 – 1.02 0.108 30064 263723 exclusion phecode
530.11 GERD Digestive 1.01 0.993 – 1.02 0.367 21680 218171 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.01 0.977 – 1.04 0.694 5076 50706 exclusion phecode
530.14 Reflux esophagitis Digestive 0.999 0.979 – 1.02 0.918 10122 101202 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.964 0.916 – 1.01 0.151 1625 16282 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1.02 0.973 – 1.07 0.405 1807 18195 exclusion phecode
530.5 Disorders of esophageal motility Digestive 0.98 0.902 – 1.06 0.628 606 6136 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.808 0.682 – 0.957 0.0135 149 1470 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.938 0.839 – 1.05 0.255 333 3332 exclusion phecode
530.9 Heartburn Digestive 1.01 0.968 – 1.06 0.568 1997 20027 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1 0.977 – 1.03 0.904 6880 68976 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.999 0.921 – 1.08 0.985 614 6250 exclusion phecode
531.2 Gastric ulcer Digestive 1 0.97 – 1.03 0.916 3966 39549 exclusion phecode
531.3 Duodenal ulcer Digestive 0.985 0.948 – 1.02 0.421 2902 29284 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.04 0.942 – 1.15 0.433 415 4125 exclusion phecode
532 Dysphagia Digestive 1.01 0.986 – 1.04 0.353 6139 62009 exclusion phecode
535 Gastritis and duodenitis Digestive 1 0.992 – 1.02 0.479 27088 252842 exclusion phecode
535.1 Acute gastritis Digestive 1.03 0.971 – 1.1 0.312 1143 11420 exclusion phecode
535.2 Atrophic gastritis Digestive 1.05 0.945 – 1.17 0.344 358 3565 exclusion phecode
535.6 Duodenitis Digestive 1.01 0.982 – 1.03 0.64 7382 73936 exclusion phecode
535.8 Other specified gastritis Digestive 1.01 0.99 – 1.04 0.281 7789 77834 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.998 0.825 – 1.21 0.982 120 1150 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.972 0.852 – 1.11 0.668 245 2487 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 0.976 0.942 – 1.01 0.185 3259 32749 exclusion phecode
540 Appendiceal conditions Digestive 0.991 0.955 – 1.03 0.642 3010 30006 exclusion phecode
540.1 Appendicitis Digestive 0.981 0.944 – 1.02 0.33 2824 28138 exclusion phecode
540.11 Acute appendicitis Digestive 0.995 0.955 – 1.04 0.806 2537 25288 exclusion phecode
550 Abdominal hernia Digestive 1 0.99 – 1.01 0.967 44115 273698 exclusion phecode
550.1 Inguinal hernia Digestive 0.995 0.979 – 1.01 0.569 15711 122486 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1 0.988 – 1.01 0.88 25417 230563 exclusion phecode
550.3 Femoral hernia Digestive 0.984 0.905 – 1.07 0.699 619 6195 exclusion phecode
550.4 Umbilical hernia Digestive 1 0.97 – 1.04 0.839 3647 36517 exclusion phecode
550.5 Ventral hernia Digestive 0.987 0.952 – 1.02 0.475 3292 33346 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 0.962 0.932 – 0.993 0.0159 4281 43184 exclusion phecode
555.1 Regional enteritis Digestive 0.941 0.894 – 0.99 0.0184 1674 16786 exclusion phecode
555.2 Ulcerative colitis Digestive 0.97 0.934 – 1.01 0.111 3058 30957 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 0.969 0.885 – 1.06 0.493 517 5237 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.01 0.949 – 1.08 0.716 1022 10222 exclusion phecode
556.1 Ulceration of intestine Digestive 0.966 0.891 – 1.05 0.409 648 6490 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.965 0.853 – 1.09 0.569 287 2894 exclusion phecode
557.1 Celiac disease Digestive 1.04 0.994 – 1.1 0.0824 1775 17705 exclusion phecode
558 Noninfectious gastroenteritis Digestive 0.998 0.981 – 1.02 0.838 14741 149690 exclusion phecode
559 Ileostomy status Digestive 0.998 0.949 – 1.05 0.953 1590 16107 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1 0.969 – 1.04 0.931 3755 38029 exclusion phecode
560.1 Paralytic ileus Digestive 1.05 0.962 – 1.15 0.27 512 5105 exclusion phecode
560.2 Impaction of intestine Digestive 1.05 0.923 – 1.2 0.457 256 2564 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.952 0.885 – 1.02 0.183 789 8048 exclusion phecode
560.4 Other intestinal obstruction Digestive 0.994 0.959 – 1.03 0.754 3191 32386 exclusion phecode
561 Symptoms involving digestive system Digestive 1.01 0.996 – 1.03 0.131 15026 151574 exclusion phecode
561.1 Diarrhea Digestive 0.985 0.893 – 1.09 0.771 435 4475 exclusion phecode
561.2 Flatulence Digestive 0.997 0.947 – 1.05 0.901 1593 16231 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 0.995 0.982 – 1.01 0.447 25637 204914 exclusion phecode
562.1 Diverticulosis Digestive 0.995 0.982 – 1.01 0.429 25598 204861 exclusion phecode
563 Constipation Digestive 1 0.981 – 1.02 0.847 9758 99467 exclusion phecode
564 Functional digestive disorders Digestive 1 0.989 – 1.02 0.685 20802 203126 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.02 0.993 – 1.05 0.147 5226 52742 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 0.972 0.923 – 1.02 0.282 1566 15816 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 0.999 0.982 – 1.02 0.934 14683 147161 exclusion phecode
565 Anal and rectal conditions Digestive 0.983 0.966 – 1 0.0517 14315 143426 exclusion phecode
565.1 Anal and rectal polyp Digestive 0.971 0.948 – 0.995 0.0187 7136 71526 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 0.949 0.886 – 1.02 0.14 889 9069 exclusion phecode
568 Other disorders of peritoneum Digestive 1.01 0.973 – 1.05 0.628 3112 31324 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.01 0.971 – 1.05 0.667 2957 29747 exclusion phecode
569 Other disorders of intestine Digestive 0.982 0.95 – 1.01 0.27 3965 40472 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.756 0.623 – 0.916 0.00437 122 1428 exclusion phecode
569.2 Gastrointestinal complications Digestive 1 0.913 – 1.1 0.933 466 4720 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.01 0.97 – 1.05 0.687 2842 28831 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.03 0.981 – 1.09 0.23 1623 16434 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.972 0.805 – 1.17 0.766 111 1097 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.03 0.906 – 1.17 0.654 239 2448 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.961 0.899 – 1.03 0.236 944 9617 exclusion phecode
571.81 Portal hypertension Digestive 0.891 0.814 – 0.976 0.0128 515 5185 exclusion phecode
572 Ascites (non malignant) Digestive 0.997 0.944 – 1.05 0.907 1397 14929 exclusion phecode
573 Other disorders of liver Digestive 0.963 0.912 – 1.02 0.169 1419 14460 exclusion phecode
573.2 Liver replaced by transplant Digestive 0.755 0.61 – 0.934 0.0097 92 945 exclusion phecode
573.3 Hepatomegaly Digestive 0.953 0.843 – 1.08 0.433 285 2899 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 0.931 0.869 – 0.999 0.0457 857 8722 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 0.982 0.947 – 1.02 0.315 3286 33501 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.08 0.936 – 1.24 0.296 201 2036 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.01 0.989 – 1.02 0.515 14825 149444 exclusion phecode
574.1 Cholelithiasis Digestive 1 0.986 – 1.02 0.665 12864 129656 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.987 0.935 – 1.04 0.627 1436 14478 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1 0.973 – 1.03 0.94 5171 51922 exclusion phecode
574.2 Calculus of bile duct Digestive 0.991 0.951 – 1.03 0.683 2497 25146 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.02 0.985 – 1.07 0.229 2614 26422 exclusion phecode
575 Other biliary tract disease Digestive 1.01 0.977 – 1.05 0.555 3651 37229 exclusion phecode
575.1 Cholangitis Digestive 0.999 0.909 – 1.1 0.98 481 4815 exclusion phecode
575.2 Obstruction of bile duct Digestive 0.954 0.885 – 1.03 0.223 736 7518 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 1.06 0.961 – 1.17 0.251 429 4380 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.04 0.986 – 1.1 0.138 1321 13542 exclusion phecode
575.8 Other disorders of biliary tract Digestive 0.989 0.927 – 1.06 0.749 982 9921 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.01 0.9 – 1.12 0.912 321 3366 exclusion phecode
577 Diseases of pancreas Digestive 0.969 0.931 – 1.01 0.131 2551 25714 exclusion phecode
577.1 Acute pancreatitis Digestive 0.98 0.935 – 1.03 0.405 1906 19260 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.01 0.919 – 1.1 0.9 509 5040 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.948 0.85 – 1.06 0.332 351 3517 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.993 – 1.02 0.297 19860 199765 exclusion phecode
578.1 Hematemesis Digestive 0.995 0.949 – 1.04 0.852 1887 19075 exclusion phecode
578.2 Blood in stool Digestive 0.99 0.95 – 1.03 0.625 2526 25535 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.02 0.999 – 1.04 0.0704 12581 126303 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.01 0.978 – 1.04 0.642 5093 51165 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.03 0.981 – 1.09 0.21 1465 14867 exclusion phecode
579.2 Splenomegaly Digestive 0.989 0.895 – 1.09 0.835 413 4163 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.998 0.948 – 1.05 0.945 1595 15990 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.01 0.961 – 1.07 0.612 1477 14898 exclusion phecode
580.1 Glomerulonephritis Genitourinary 0.987 0.925 – 1.05 0.687 1010 10204 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.918 0.719 – 1.17 0.495 73 716 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.02 0.851 – 1.22 0.843 131 1319 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.982 0.915 – 1.05 0.614 839 8476 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.1 1 – 1.21 0.0496 460 4588 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.995 0.87 – 1.14 0.939 237 2401 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1 0.876 – 1.14 0.986 244 2471 exclusion phecode
585 Renal failure Genitourinary 0.995 0.97 – 1.02 0.674 6669 67938 exclusion phecode
585.1 Acute renal failure Genitourinary 0.998 0.967 – 1.03 0.907 4323 44204 exclusion phecode
585.2 Renal failure NOS Genitourinary 0.978 0.927 – 1.03 0.424 1409 14280 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.998 0.958 – 1.04 0.91 2544 25771 exclusion phecode
585.31 Renal dialysis Genitourinary 0.956 0.869 – 1.05 0.356 477 4858 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.05 1.01 – 1.09 0.0112 3238 32690 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.921 0.798 – 1.06 0.264 201 2030 exclusion phecode
586.11 Small kidney Genitourinary 0.931 0.797 – 1.09 0.367 174 1748 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.06 1 – 1.13 0.044 1220 12241 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.969 0.782 – 1.2 0.771 78 787 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.06 0.985 – 1.13 0.123 874 8878 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.04 0.932 – 1.16 0.476 350 3604 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.01 0.822 – 1.25 0.902 98 954 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 0.859 0.711 – 1.04 0.117 109 1119 exclusion phecode
590 Pyelonephritis Genitourinary 1.04 0.986 – 1.11 0.138 1260 12753 exclusion phecode
591 Urinary tract infection Genitourinary 1.02 0.996 – 1.03 0.111 11735 119390 exclusion phecode
592 Cystitis and urethritis Genitourinary 0.996 0.958 – 1.04 0.845 2840 28450 exclusion phecode
592.1 Cystitis Genitourinary 0.998 0.96 – 1.04 0.92 2780 27825 exclusion phecode
592.11 Acute cystitis Genitourinary 0.871 0.726 – 1.04 0.136 137 1325 exclusion phecode
592.12 Chronic cystitis Genitourinary 1.02 0.947 – 1.09 0.669 847 8511 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.04 0.907 – 1.18 0.596 237 2344 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.01 0.86 – 1.18 0.926 162 1619 exclusion phecode
593 Hematuria Genitourinary 1.01 0.991 – 1.02 0.394 15600 155884 exclusion phecode
594 Urinary calculus Genitourinary 0.999 0.973 – 1.02 0.918 6234 62613 exclusion phecode
594.1 Calculus of kidney Genitourinary 0.988 0.952 – 1.03 0.524 3097 31123 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 0.947 0.879 – 1.02 0.147 764 7686 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.01 0.965 – 1.05 0.763 2367 23720 exclusion phecode
594.8 Renal colic Genitourinary 1.03 0.986 – 1.08 0.173 2008 20149 exclusion phecode
595 Hydronephrosis Genitourinary 1.02 0.968 – 1.07 0.526 1850 18945 exclusion phecode
596 Other disorders of bladder Genitourinary 0.997 0.976 – 1.02 0.798 9500 95543 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.04 0.996 – 1.09 0.0725 1957 19625 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 0.996 0.946 – 1.05 0.876 1601 16007 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.01 0.979 – 1.05 0.477 3782 38016 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.02 0.984 – 1.06 0.277 3216 32287 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.08 0.856 – 1.35 0.53 75 749 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1 0.97 – 1.04 0.794 3437 34518 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.13 0.998 – 1.27 0.054 288 2945 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.99 – 1.02 0.477 17688 177834 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.948 0.804 – 1.12 0.526 161 1645 exclusion phecode
599.2 Retention of urine Genitourinary 0.996 0.971 – 1.02 0.759 6564 66108 exclusion phecode
599.3 Dysuria Genitourinary 0.96 0.904 – 1.02 0.178 1148 11610 exclusion phecode
599.4 Urinary incontinence Genitourinary 1.01 0.989 – 1.03 0.335 8270 82937 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.01 0.974 – 1.04 0.711 3904 39055 exclusion phecode
599.6 Oliguria and anuria Genitourinary 0.982 0.801 – 1.2 0.858 99 1020 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 0.849 0.653 – 1.11 0.224 58 602 exclusion phecode
599.9 Other abnormality of urination Genitourinary 0.98 0.934 – 1.03 0.401 1873 18791 exclusion phecode
600 Hyperplasia of prostate Genitourinary 1 0.983 – 1.02 0.759 11082 87821 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 0.982 0.939 – 1.03 0.419 2080 20803 exclusion phecode
601.1 Prostatitis Genitourinary 0.968 0.919 – 1.02 0.214 1562 15634 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.927 0.811 – 1.06 0.268 234 2357 exclusion phecode
601.12 Chronic prostatitis Genitourinary 0.934 0.873 – 1 0.0496 910 9081 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.857 0.656 – 1.12 0.259 59 588 exclusion phecode
601.4 Balanoposthitis Genitourinary 1 0.885 – 1.13 0.983 287 2862 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.09 0.967 – 1.22 0.162 303 3017 exclusion phecode
602 Other disorders of prostate Genitourinary 0.988 0.933 – 1.05 0.667 1338 13394 exclusion phecode
603 Other disorders of testis Genitourinary 0.991 0.948 – 1.04 0.685 2146 21499 exclusion phecode
603.1 Hydrocele Genitourinary 1.03 0.969 – 1.08 0.387 1337 13393 exclusion phecode
604 Disorders of penis Genitourinary 1.01 0.977 – 1.05 0.475 3276 32764 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.02 0.984 – 1.06 0.246 2718 27161 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 1.02 0.906 – 1.15 0.735 278 2799 exclusion phecode
608 Other disorders of male genital organs Genitourinary 0.998 0.96 – 1.04 0.918 2820 28217 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.899 0.779 – 1.04 0.144 213 2136 exclusion phecode
609.1 Infertility, male Genitourinary 1.01 0.783 – 1.3 0.938 63 638 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.895 0.762 – 1.05 0.18 168 1696 exclusion phecode
610 Benign mammary dysplasias Genitourinary 1.1 1.05 – 1.15 0.000121 1883 23623 exclusion phecode
610.1 Cystic mastopathy Genitourinary 1.08 1 – 1.16 0.0455 720 8745 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1.18 1.01 – 1.37 0.032 179 2892 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 1.14 0.981 – 1.32 0.0883 184 2871 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 1.11 1.04 – 1.18 0.00088 1131 13188 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.08 0.995 – 1.18 0.065 570 6579 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.1 1.03 – 1.17 0.00227 1094 14957 exclusion phecode
611.3 Lump or mass in breast Genitourinary 1.1 1.03 – 1.17 0.00357 1062 14482 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.11 1.03 – 1.2 0.00459 747 8533 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.11 1.03 – 1.2 0.00601 715 8164 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 1.06 0.827 – 1.36 0.65 63 688 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 1.14 1.08 – 1.21 1.56e-05 1123 15621 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.07 0.977 – 1.17 0.147 489 6849 exclusion phecode
613.5 Mastodynia Genitourinary 1.04 0.796 – 1.37 0.755 52 735 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 1.21 1.11 – 1.31 1.04e-05 580 6605 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1.16 0.998 – 1.36 0.0537 171 3110 exclusion phecode
613.9 Breast disorder NOS Genitourinary 1.17 0.994 – 1.38 0.0589 139 1937 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.01 0.981 – 1.04 0.532 5351 54199 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.02 0.983 – 1.07 0.256 2404 24133 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.01 0.937 – 1.09 0.816 779 7899 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.01 0.758 – 1.35 0.938 55 571 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.05 0.947 – 1.16 0.361 397 4011 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.966 0.862 – 1.08 0.552 328 3345 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.05 0.919 – 1.19 0.494 250 2642 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.99 0.95 – 1.03 0.636 2427 24640 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.993 0.937 – 1.05 0.815 1229 12479 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.06 0.959 – 1.18 0.248 399 4019 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.969 0.898 – 1.05 0.427 707 7170 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.977 0.859 – 1.11 0.731 250 2579 exclusion phecode
615 Endometriosis Genitourinary 1.02 0.986 – 1.05 0.259 3799 38316 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 0.963 0.851 – 1.09 0.556 277 2873 exclusion phecode
618 Genital prolapse Genitourinary 1.02 1 – 1.04 0.0298 10983 109367 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 1.02 0.992 – 1.04 0.181 6944 69176 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.01 0.981 – 1.04 0.531 5058 50422 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.02 0.926 – 1.11 0.744 493 4747 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.04 0.962 – 1.13 0.308 635 6336 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1.02 0.993 – 1.04 0.177 8075 82518 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.958 0.885 – 1.04 0.286 670 6936 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 1 0.966 – 1.04 0.876 3022 31318 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.01 0.968 – 1.05 0.732 2667 27073 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.05 0.998 – 1.1 0.0616 1639 16655 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.04 0.986 – 1.1 0.142 1272 12763 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 0.976 0.771 – 1.23 0.837 65 679 exclusion phecode
621 Endometrial hyperplasia Genitourinary 1.02 0.96 – 1.09 0.468 979 10644 exclusion phecode
622 Polyp of female genital organs Genitourinary 1.03 1.01 – 1.05 0.0111 9371 98870 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 1.02 0.992 – 1.04 0.179 6936 74136 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 1.04 1 – 1.08 0.0292 3160 32418 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.02 0.963 – 1.09 0.452 1172 12060 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.947 0.878 – 1.02 0.153 730 7402 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.953 0.83 – 1.1 0.5 220 2208 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 0.953 0.861 – 1.06 0.353 397 4080 exclusion phecode
624.9 stress incontinence, female Genitourinary 1 0.974 – 1.03 0.945 5521 55090 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.02 0.978 – 1.06 0.398 2725 27372 exclusion phecode
625.1 Dyspareunia Genitourinary 1.03 0.97 – 1.1 0.318 1130 11313 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.02 1 – 1.04 0.0237 15278 109469 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.02 1 – 1.04 0.0162 13378 104677 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.97 0.797 – 1.18 0.759 100 1059 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1.02 0.995 – 1.04 0.135 9249 87559 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 1.06 1.01 – 1.11 0.0282 1845 18826 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 1.03 0.997 – 1.07 0.0774 3612 36268 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.996 0.948 – 1.05 0.87 1709 17054 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.864 0.734 – 1.02 0.0792 154 1530 exclusion phecode
626.8 Infertility, female Genitourinary 1 0.947 – 1.06 0.936 1303 13128 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.01 0.993 – 1.04 0.201 9194 97523 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 1.02 0.994 – 1.04 0.156 7940 84785 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.834 0.711 – 0.978 0.0258 166 1711 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.99 0.928 – 1.06 0.767 1000 10418 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 0.994 0.883 – 1.12 0.927 297 2931 exclusion phecode
628 Ovarian cyst Genitourinary 0.987 0.956 – 1.02 0.391 4412 45211 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.01 0.978 – 1.04 0.615 5032 35198 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.979 0.92 – 1.04 0.495 1092 10946 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.09 0.977 – 1.23 0.119 318 3184 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.05 0.998 – 1.1 0.0595 1912 16882 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.03 0.958 – 1.1 0.449 841 8372 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.04 0.978 – 1.1 0.231 1228 11979 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.03 0.988 – 1.08 0.163 2272 19393 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 1.05 0.969 – 1.15 0.225 597 5972 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.07 1.01 – 1.14 0.0295 1038 10442 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 1.13 0.88 – 1.44 0.343 69 676 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.03 0.965 – 1.09 0.396 1087 10778 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.986 0.875 – 1.11 0.816 301 2970 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.07 0.936 – 1.24 0.308 212 2090 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.09 0.923 – 1.28 0.321 152 1484 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.03 0.97 – 1.09 0.356 1219 12107 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.03 0.987 – 1.08 0.172 2166 20249 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.46 1.12 – 1.9 0.00506 65 650 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.11 0.984 – 1.26 0.0904 271 2665 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.3 1.07 – 1.58 0.00852 111 1104 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.17 1.01 – 1.36 0.0331 185 1870 exclusion phecode
650 Normal delivery Pregnancy Complications 1.02 0.973 – 1.07 0.401 1870 18412 exclusion phecode
651 Multiple gestation Pregnancy Complications 1.01 0.902 – 1.13 0.887 339 3349 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1 0.954 – 1.05 0.904 1670 16087 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.01 0.951 – 1.06 0.853 1361 13271 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.27 0.998 – 1.63 0.0523 70 723 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.996 0.964 – 1.03 0.822 4175 28574 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.952 0.789 – 1.15 0.611 109 1051 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.997 0.954 – 1.04 0.898 2195 17883 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.962 0.88 – 1.05 0.395 521 5167 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 1.04 1 – 1.07 0.0244 5179 28548 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.03 0.983 – 1.07 0.242 2469 20539 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.02 0.862 – 1.2 0.826 157 1577 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.13 0.997 – 1.28 0.0564 255 2541 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.946 0.721 – 1.24 0.69 60 612 exclusion phecode
679 Complications of in utero procedures Dermatologic 0.893 0.672 – 1.19 0.437 51 513 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 0.975 0.951 – 1 0.0476 6754 70395 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.02 0.934 – 1.11 0.659 535 5478 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.99 0.903 – 1.09 0.833 497 5024 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.967 0.939 – 0.994 0.0187 5221 53756 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.967 0.94 – 0.994 0.0192 5226 53817 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.965 0.938 – 0.993 0.0133 5186 53387 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.02 0.932 – 1.12 0.647 491 5781 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.03 0.976 – 1.1 0.253 1264 13069 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1 0.96 – 1.05 0.908 2210 22339 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.03 0.942 – 1.12 0.555 572 5762 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 0.99 0.888 – 1.1 0.86 343 3500 exclusion phecode
687 Symptoms affecting skin Dermatologic 1.09 0.997 – 1.19 0.0593 518 5299 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1 0.96 – 1.05 0.843 2017 20814 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.13 1 – 1.29 0.0492 265 2736 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.996 0.816 – 1.21 0.966 104 1035 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.05 1.01 – 1.09 0.0123 2780 27926 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.01 0.987 – 1.04 0.308 5459 55556 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.766 0.602 – 0.974 0.0294 70 702 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.673 0.508 – 0.893 0.00595 53 527 exclusion phecode
691 Congenital anomalies of skin Dermatologic 1.17 0.97 – 1.42 0.1 112 1155 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 1 0.939 – 1.07 0.904 933 9479 exclusion phecode
694.1 Vitiligo Dermatologic 0.961 0.739 – 1.25 0.767 58 574 exclusion phecode
694.2 Other dyschromia Dermatologic 1 0.928 – 1.08 0.994 740 7517 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 0.935 0.766 – 1.14 0.513 110 1137 exclusion phecode
695 Erythematous conditions Dermatologic 1.01 0.97 – 1.06 0.556 2247 22923 exclusion phecode
695.1 Toxic erythema Dermatologic 0.945 0.778 – 1.15 0.565 105 1043 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.06 0.886 – 1.27 0.517 129 1318 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 0.995 0.756 – 1.31 0.971 53 552 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.09 0.854 – 1.39 0.495 69 697 exclusion phecode
695.3 Rosacea Dermatologic 1.05 0.932 – 1.18 0.432 300 3000 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.03 0.927 – 1.13 0.628 398 3902 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.14 0.95 – 1.36 0.162 125 1238 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 0.991 0.887 – 1.11 0.876 329 3224 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 0.99 0.917 – 1.07 0.793 731 7461 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1.01 0.886 – 1.16 0.834 219 2282 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.947 0.748 – 1.2 0.655 71 733 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.01 0.913 – 1.11 0.87 427 4540 exclusion phecode
696 Psoriasis and related disorders Dermatologic 1.01 0.966 – 1.05 0.668 2168 21893 exclusion phecode
696.4 Psoriasis Dermatologic 1.01 0.965 – 1.05 0.689 2114 21361 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 1.02 0.973 – 1.08 0.358 1604 16325 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.97 0.897 – 1.05 0.44 692 6836 exclusion phecode
697 Sarcoidosis Dermatologic 1.02 0.928 – 1.11 0.718 510 5188 exclusion phecode
698 Pruritus and related conditions Dermatologic 1.08 1 – 1.16 0.047 752 7527 exclusion phecode
700 Corns and callosities Dermatologic 0.911 0.807 – 1.03 0.132 278 2763 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.01 0.977 – 1.04 0.609 4116 45006 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 1.04 0.826 – 1.3 0.761 83 845 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.999 0.954 – 1.05 0.962 1969 22605 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 1.22 0.923 – 1.6 0.165 59 579 exclusion phecode
701.4 Keloid scar Dermatologic 1.21 1.04 – 1.41 0.0117 182 2073 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 0.95 0.859 – 1.05 0.323 417 4394 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 0.969 0.783 – 1.2 0.771 97 975 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.01 0.98 – 1.04 0.566 5200 52601 exclusion phecode
702.1 Actinic keratosis Dermatologic 1.03 0.988 – 1.07 0.16 2490 24879 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.986 0.949 – 1.02 0.474 2903 29611 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.05 0.939 – 1.17 0.391 338 3415 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.996 0.931 – 1.07 0.906 935 9400 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.984 0.956 – 1.01 0.259 5073 51172 exclusion phecode
704.1 Alopecia Dermatologic 1.1 0.918 – 1.31 0.309 118 1198 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.936 0.747 – 1.17 0.563 74 734 exclusion phecode
705 Disorders of sweat glands Dermatologic 1 0.872 – 1.15 0.979 224 2215 exclusion phecode
705.3 Hidradenitis Dermatologic 1.02 0.88 – 1.19 0.771 182 1804 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.11 1.02 – 1.21 0.0125 583 5785 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1 0.979 – 1.02 0.911 8013 80635 exclusion phecode
706.1 Acne Dermatologic 1.21 0.955 – 1.53 0.116 75 757 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1 0.978 – 1.02 0.993 8466 85173 exclusion phecode
707 Chronic ulcer of skin Dermatologic 0.988 0.942 – 1.04 0.619 1870 19141 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.02 0.952 – 1.09 0.581 861 8851 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 1.01 0.971 – 1.04 0.736 3247 32831 exclusion phecode
709.2 Sicca syndrome Dermatologic 0.892 0.813 – 0.98 0.017 473 4776 exclusion phecode
709.3 Systemic sclerosis Dermatologic 0.92 0.781 – 1.08 0.319 165 1665 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.03 0.794 – 1.34 0.822 59 618 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.02 0.984 – 1.07 0.241 2577 26058 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.1 1.01 – 1.2 0.0277 581 5890 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.09 0.998 – 1.19 0.056 537 5438 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.02 0.878 – 1.19 0.794 187 1899 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.06 0.958 – 1.18 0.251 386 3903 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 1.01 0.913 – 1.12 0.827 414 4110 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.02 0.91 – 1.15 0.723 322 3215 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 0.915 0.723 – 1.16 0.459 78 781 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.04 0.875 – 1.23 0.66 145 1458 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.09 0.845 – 1.41 0.505 63 662 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.02 0.988 – 1.05 0.232 4590 46275 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.02 0.984 – 1.05 0.331 4161 41863 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.996 0.946 – 1.05 0.892 1573 16048 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.983 0.81 – 1.19 0.86 110 1078 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.972 0.895 – 1.06 0.499 600 6049 exclusion phecode
716 Other arthropathies Musculoskeletal 1 0.989 – 1.01 0.932 35647 256935 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.03 0.995 – 1.07 0.0893 3306 33554 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.989 0.972 – 1.01 0.2 14915 150303 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 0.998 0.987 – 1.01 0.764 34200 253946 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.01 0.952 – 1.08 0.686 1094 10903 exclusion phecode
720 Spinal stenosis Musculoskeletal 1.02 0.983 – 1.05 0.32 3562 35801 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1.02 0.992 – 1.04 0.181 7431 75200 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.03 1 – 1.06 0.0393 4798 48447 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.01 0.873 – 1.18 0.86 178 1852 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 0.976 0.873 – 1.09 0.672 331 3386 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.01 0.987 – 1.03 0.438 8658 86963 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.941 0.859 – 1.03 0.196 497 4983 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.98 0.942 – 1.02 0.311 2718 27318 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.19 0.928 – 1.54 0.169 63 655 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.995 0.964 – 1.03 0.741 4254 42786 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.04 0.949 – 1.14 0.399 497 5043 exclusion phecode
723.1 Torticollis Musculoskeletal 1 0.821 – 1.22 0.996 102 1025 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.02 0.974 – 1.07 0.385 1963 19868 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1.03 0.929 – 1.15 0.556 383 3844 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 1.04 0.938 – 1.16 0.448 386 3876 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 0.858 0.664 – 1.11 0.239 58 600 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.01 0.962 – 1.07 0.604 1549 15689 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.02 0.999 – 1.03 0.073 14198 141816 exclusion phecode
726.1 Enthesopathy Musculoskeletal 1.02 1 – 1.04 0.0474 9269 92496 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.969 0.865 – 1.08 0.583 318 3214 exclusion phecode
726.3 Bursitis Musculoskeletal 0.983 0.916 – 1.06 0.632 844 8454 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.987 0.963 – 1.01 0.292 7051 70688 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.986 0.948 – 1.03 0.499 2643 26427 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 1.14 0.929 – 1.39 0.215 102 1006 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.977 0.941 – 1.01 0.222 2979 29838 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 1.01 0.927 – 1.1 0.798 560 5641 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.977 0.874 – 1.09 0.69 336 3416 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.994 0.837 – 1.18 0.947 138 1384 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.03 0.991 – 1.06 0.148 3602 36133 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.02 0.926 – 1.13 0.635 402 4004 exclusion phecode
728.7 Fasciitis Musculoskeletal 1.03 0.992 – 1.06 0.129 3724 37323 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.03 0.993 – 1.06 0.122 3407 34185 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 0.992 0.965 – 1.02 0.551 5696 58101 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.997 0.932 – 1.07 0.924 945 9546 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.878 0.72 – 1.07 0.202 97 982 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.06 0.936 – 1.2 0.367 257 2652 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.06 0.936 – 1.21 0.349 243 2511 exclusion phecode
732 Osteochondropathies Musculoskeletal 1.05 0.952 – 1.15 0.34 453 4545 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.06 0.918 – 1.22 0.423 198 2014 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.993 0.759 – 1.3 0.962 56 564 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 1 0.949 – 1.05 0.987 1553 16986 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.08 0.937 – 1.24 0.297 211 2962 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.918 0.838 – 1.01 0.0642 507 5206 exclusion phecode
733.6 Costochondritis Musculoskeletal 0.982 0.822 – 1.17 0.845 124 1220 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.979 0.921 – 1.04 0.483 1181 11924 exclusion phecode
733.9 Chondromalacia Musculoskeletal 0.916 0.757 – 1.11 0.37 116 1173 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1 0.981 – 1.02 0.82 9051 90789 exclusion phecode
735.1 Flat foot Musculoskeletal 0.965 0.825 – 1.13 0.655 175 1848 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 0.994 0.965 – 1.02 0.683 4784 47984 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.993 0.946 – 1.04 0.769 1825 18237 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 1.01 0.957 – 1.07 0.718 1461 14783 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.999 0.974 – 1.03 0.966 6255 62528 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1 0.953 – 1.06 0.858 1559 15691 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.03 0.899 – 1.17 0.706 243 2397 exclusion phecode
737 Curvature of spine Musculoskeletal 1 0.94 – 1.07 0.96 1059 10736 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.99 0.927 – 1.06 0.755 994 10087 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.964 0.918 – 1.01 0.135 1821 18241 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.955 0.904 – 1.01 0.0963 1441 14441 exclusion phecode
739 Contracture of joint Musculoskeletal 1.04 0.95 – 1.15 0.374 471 4698 exclusion phecode
740 Osteoarthrosis Musculoskeletal 0.995 0.983 – 1.01 0.48 26358 223479 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.991 0.975 – 1.01 0.248 16646 163111 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.995 0.973 – 1.02 0.673 8604 86448 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.09 0.969 – 1.22 0.155 334 3350 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.03 0.949 – 1.13 0.44 569 5700 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.01 0.991 – 1.03 0.279 11561 117767 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.981 0.948 – 1.02 0.288 3437 34498 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.873 0.708 – 1.08 0.202 98 982 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 0.988 0.909 – 1.07 0.77 595 5934 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.912 0.769 – 1.08 0.292 145 1486 exclusion phecode
741.4 Joint effusions Musculoskeletal 0.984 0.931 – 1.04 0.566 1363 13791 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 0.951 0.782 – 1.16 0.617 104 1065 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.788 0.6 – 1.03 0.0856 51 515 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.975 0.938 – 1.01 0.206 2774 27658 exclusion phecode
742.1 Loose body in joint Musculoskeletal 1.05 0.939 – 1.18 0.373 322 3262 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.909 0.736 – 1.12 0.379 94 941 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 0.914 0.832 – 1 0.0606 481 4844 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.971 0.927 – 1.02 0.216 1956 19390 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.01 0.981 – 1.03 0.64 6905 71858 exclusion phecode
743.1 Osteoporosis Musculoskeletal 0.998 0.971 – 1.03 0.875 5809 60678 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.01 0.984 – 1.04 0.387 5003 52449 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 0.979 0.893 – 1.07 0.646 498 5118 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 0.973 0.885 – 1.07 0.571 475 4972 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.09 1.01 – 1.17 0.0203 772 7831 exclusion phecode
745 Pain in joint Musculoskeletal 0.996 0.973 – 1.02 0.734 7627 76938 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.966 0.929 – 1.01 0.0917 2702 27276 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.969 0.93 – 1.01 0.133 2534 25608 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.915 0.839 – 0.997 0.043 563 5643 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.961 0.838 – 1.1 0.563 225 2307 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.975 0.928 – 1.02 0.31 1748 17745 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.901 0.764 – 1.06 0.22 160 1618 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.05 0.93 – 1.18 0.456 297 2949 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 1.02 0.938 – 1.1 0.699 652 6670 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.996 0.886 – 1.12 0.951 315 3175 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.03 0.885 – 1.19 0.72 187 1861 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.04 0.934 – 1.16 0.457 335 3462 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.01 0.884 – 1.16 0.843 212 2193 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1 0.829 – 1.22 0.965 109 1130 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.03 0.977 – 1.09 0.274 1468 14841 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.03 0.947 – 1.11 0.535 667 6695 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.05 0.949 – 1.15 0.365 429 4309 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.975 0.847 – 1.12 0.72 220 2214 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.03 0.963 – 1.11 0.356 803 8171 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 1.12 1.01 – 1.23 0.0325 407 4153 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.979 0.873 – 1.1 0.715 320 3228 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.17 1.05 – 1.31 0.0061 316 3195 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.17 1.03 – 1.33 0.0163 245 2472 exclusion phecode
752.11 Spina bifida Congenital Anomalies 1.16 1.01 – 1.34 0.0335 203 2041 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.14 0.901 – 1.44 0.278 73 760 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.884 0.735 – 1.06 0.19 123 1218 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.947 0.739 – 1.21 0.666 73 734 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.975 0.786 – 1.21 0.82 99 1051 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.913 0.824 – 1.01 0.0834 413 4090 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.97 0.838 – 1.12 0.68 204 1991 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.881 0.747 – 1.04 0.134 156 1539 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.893 0.733 – 1.09 0.259 104 1012 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.935 0.856 – 1.02 0.138 563 5649 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.909 0.722 – 1.14 0.413 79 778 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.958 0.864 – 1.06 0.407 419 4195 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.987 0.835 – 1.17 0.88 139 1649 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.14 0.864 – 1.49 0.36 51 801 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.03 0.896 – 1.18 0.676 206 2087 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.894 0.727 – 1.1 0.286 94 920 exclusion phecode
760 Back pain Symptoms 1.01 0.994 – 1.03 0.175 10641 107485 exclusion phecode
761 Cervicalgia Symptoms 0.981 0.933 – 1.03 0.455 1714 17304 exclusion phecode
764 Sciatica Symptoms 1.01 0.972 – 1.06 0.505 2278 22854 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.01 0.946 – 1.07 0.83 1116 11313 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.01 0.926 – 1.09 0.885 601 6105 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.986 0.918 – 1.06 0.708 823 8388 exclusion phecode
771.1 Swelling of limb Symptoms 0.992 0.962 – 1.02 0.627 4374 44747 exclusion phecode
772 Symptoms of the muscles Symptoms 0.965 0.889 – 1.05 0.4 632 6387 exclusion phecode
773 Pain in limb Symptoms 1.02 0.991 – 1.04 0.204 5930 59940 exclusion phecode
780 Hypothermia/Chills Symptoms 0.954 0.809 – 1.12 0.571 158 1659 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1 0.952 – 1.05 0.992 1785 18158 exclusion phecode
782.3 Edema Symptoms 1.01 0.959 – 1.06 0.709 1544 15897 exclusion phecode
782.6 Pallor and flushing Symptoms 1.08 0.918 – 1.27 0.353 162 1697 exclusion phecode
783 Fever of unknown origin Symptoms 0.997 0.963 – 1.03 0.848 3475 37922 exclusion phecode
785 Abdominal pain Symptoms 1.02 1.01 – 1.03 0.00104 38482 292262 exclusion phecode
788 Syncope and collapse Symptoms 0.998 0.977 – 1.02 0.876 8729 88191 exclusion phecode
789 Nausea and vomiting Symptoms 1.02 1 – 1.04 0.0316 10790 111496 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.01 0.847 – 1.2 0.937 143 1445 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.02 0.809 – 1.3 0.845 77 802 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 0.982 0.956 – 1.01 0.17 6184 62714 exclusion phecode
791 Gangrene Symptoms 0.985 0.901 – 1.08 0.745 520 5379 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.942 0.767 – 1.16 0.567 95 966 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.927 0.77 – 1.12 0.42 114 1300 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.03 0.945 – 1.13 0.466 516 5456 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.999 0.828 – 1.2 0.989 117 1173 exclusion phecode
797 Shock Symptoms 1.13 0.961 – 1.33 0.138 152 1531 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.07 0.87 – 1.3 0.538 102 1005 exclusion phecode
798 Malaise and fatigue Symptoms 0.996 0.96 – 1.03 0.831 3181 32896 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1.05 0.964 – 1.15 0.261 561 5663 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 0.98 0.955 – 1 0.106 6720 67642 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.946 0.9 – 0.994 0.0287 1720 17359 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.954 0.813 – 1.12 0.56 162 1630 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1 0.96 – 1.05 0.872 2081 20930 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.99 0.919 – 1.07 0.797 745 7459 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.976 0.933 – 1.02 0.277 2114 21254 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 0.988 0.941 – 1.04 0.612 1757 17698 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 0.998 0.923 – 1.08 0.955 691 6939 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 1.01 0.988 – 1.04 0.328 7885 79487 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 0.986 0.937 – 1.04 0.585 1610 16201 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1 0.973 – 1.03 0.917 4932 49662 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.04 0.988 – 1.1 0.125 1473 14930 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.974 0.939 – 1.01 0.146 3234 32439 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.978 0.924 – 1.04 0.454 1292 13198 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.01 0.939 – 1.09 0.772 760 7589 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.961 0.907 – 1.02 0.185 1263 12641 exclusion phecode
817 Concussion Injuries & Poisonings 0.941 0.825 – 1.07 0.369 235 2367 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.958 0.874 – 1.05 0.361 506 5089 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.02 0.982 – 1.06 0.294 2897 29043 exclusion phecode
823 Torus fracture Injuries & Poisonings 1.01 0.96 – 1.06 0.718 1615 16204 exclusion phecode
830 Dislocation Injuries & Poisonings 0.968 0.924 – 1.01 0.16 2040 20395 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.998 0.981 – 1.01 0.789 14824 148273 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 1.08 0.988 – 1.18 0.0889 505 5132 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.959 0.87 – 1.06 0.39 461 4600 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.992 0.962 – 1.02 0.583 4604 50976 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.916 0.768 – 1.09 0.333 130 1516 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 0.943 0.859 – 1.04 0.219 473 4889 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.973 0.926 – 1.02 0.269 1738 17885 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1 0.942 – 1.06 0.994 1200 12086 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.937 0.903 – 0.973 0.000702 3028 30471 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.01 0.968 – 1.04 0.77 2914 31400 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 0.958 0.754 – 1.22 0.726 66 661 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.01 0.975 – 1.05 0.564 3399 34307 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.974 0.861 – 1.1 0.679 258 2655 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 0.959 0.829 – 1.11 0.578 191 1911 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.02 0.984 – 1.06 0.26 2825 28437 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.05 0.909 – 1.21 0.523 213 2163 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 1.02 0.802 – 1.31 0.848 68 666 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 0.983 0.952 – 1.02 0.315 3985 39843 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.04 0.79 – 1.36 0.794 53 526 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.1 0.889 – 1.35 0.392 88 877 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.01 0.862 – 1.17 0.94 170 1731 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 0.973 0.884 – 1.07 0.577 472 4688 exclusion phecode
873 Broken tooth Injuries & Poisonings 1.07 0.936 – 1.23 0.313 222 2211 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.05 0.895 – 1.22 0.568 167 1689 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.05 0.888 – 1.24 0.571 149 1536 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 0.978 0.923 – 1.04 0.45 1282 12839 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.01 0.975 – 1.04 0.666 4096 41482 exclusion phecode
916 Contusion Injuries & Poisonings 0.974 0.921 – 1.03 0.347 1401 14081 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.92 0.785 – 1.08 0.303 171 1728 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.974 0.875 – 1.08 0.636 369 3772 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.967 0.848 – 1.1 0.621 246 2457 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.966 0.923 – 1.01 0.139 1984 20324 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.07 0.926 – 1.23 0.375 206 2167 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.05 0.849 – 1.29 0.673 92 1006 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.04 0.952 – 1.14 0.371 520 5321 exclusion phecode
947 Urticaria Injuries & Poisonings 0.921 0.828 – 1.03 0.132 354 3563 exclusion phecode
949 Allergies, other Injuries & Poisonings 0.981 0.883 – 1.09 0.719 384 3852 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.943 0.852 – 1.04 0.257 409 4114 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.05 0.922 – 1.19 0.487 259 2585 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.96 0.873 – 1.06 0.403 475 4825 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 0.959 0.731 – 1.26 0.762 54 543 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.06 0.835 – 1.35 0.63 73 731 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.02 1 – 1.03 0.0573 16929 174200 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.02 0.999 – 1.03 0.0586 14859 152759 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 0.953 0.86 – 1.06 0.353 389 4013 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.02 0.949 – 1.1 0.584 781 8254 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.98 0.877 – 1.09 0.718 340 3571 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 0.984 0.88 – 1.1 0.784 335 3501 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.14 0.993 – 1.31 0.0637 204 2160 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.863 0.764 – 0.974 0.0175 267 2773 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.879 0.778 – 0.994 0.0395 260 2715 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1 0.975 – 1.03 0.898 5720 58634 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.963 0.904 – 1.03 0.247 1031 10931 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.924 0.84 – 1.02 0.102 458 4644 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.11 1 – 1.23 0.0456 394 3949 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.968 0.883 – 1.06 0.485 497 4957 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.03 0.939 – 1.12 0.573 541 5637 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 0.993 0.947 – 1.04 0.763 1884 18988 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.993 0.855 – 1.15 0.927 186 1863 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.1 0.971 – 1.24 0.135 265 2647 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.05 0.843 – 1.31 0.656 82 836 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.04 0.849 – 1.27 0.716 106 1053 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.915 0.742 – 1.13 0.405 98 996 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.92 0.712 – 1.19 0.526 61 612 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.01 0.754 – 1.35 0.959 53 561 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.07 0.932 – 1.23 0.341 215 2258 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.07 0.984 – 1.15 0.116 668 6752 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.933 0.807 – 1.08 0.345 195 1937 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.1 0.848 – 1.44 0.461 61 606 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.04 0.855 – 1.27 0.683 104 1030 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.988 0.81 – 1.21 0.909 106 1086 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.02 0.814 – 1.27 0.877 85 867 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.01 0.967 – 1.06 0.637 2105 30165 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.01 0.967 – 1.05 0.741 2553 29336 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.01 0.967 – 1.05 0.741 2553 29336 exclusion phecode
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