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Scores Malignant neoplasm of ovary UK Biobank (UKB) PheWAS analysis

Malignant neoplasm of ovary — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID prsweb-phecode184-11-phelan-lsasboc-p-5e-08-ukb-20200608Legacy P_5e-08GWAS HitsPhelan CM et al. 2017

Evaluation cohort: UK Biobank (UKB).

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116 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.01 0.984 – 1.03 0.609 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 0.994 0.955 – 1.03 0.754 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.02 0.94 – 1.11 0.637 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 1.02 0.949 – 1.09 0.62 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.71 1.24 – 2.35 0.00108 55 550 all phecode
010 Tuberculosis Infectious Diseases 0.892 0.764 – 1.04 0.148 166 1659 all phecode
038 Septicemia Infectious Diseases 1.03 0.995 – 1.06 0.0952 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.08 1 – 1.16 0.0411 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.01 0.925 – 1.11 0.767 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 1 0.982 – 1.02 0.989 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 0.99 0.954 – 1.03 0.58 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 0.99 0.94 – 1.04 0.685 1641 16433 all phecode
041.4 E. coli Infectious Diseases 1.02 0.977 – 1.06 0.423 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 1.09 0.982 – 1.21 0.108 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.19 0.958 – 1.48 0.116 95 949 all phecode
054 Herpes simplex Infectious Diseases 1.1 0.955 – 1.26 0.192 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 0.972 0.894 – 1.06 0.507 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 0.956 0.742 – 1.23 0.726 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 0.991 0.832 – 1.18 0.922 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 0.965 0.853 – 1.09 0.579 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.08 0.95 – 1.23 0.242 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 0.912 0.826 – 1.01 0.0703 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.829 0.704 – 0.977 0.0247 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.809 0.676 – 0.968 0.0207 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 1.01 0.95 – 1.08 0.68 1004 10036 all phecode
079 Viral infection Infectious Diseases 1 0.966 – 1.05 0.807 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 1.06 0.826 – 1.36 0.641 64 640 all phecode
080 Postoperative infection Infectious Diseases 1.02 0.988 – 1.05 0.238 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.03 0.991 – 1.08 0.124 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.03 0.809 – 1.32 0.787 71 709 all phecode
1000 Burns Injuries & Poisonings 1.05 0.964 – 1.15 0.255 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 0.986 0.929 – 1.05 0.632 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.01 0.985 – 1.04 0.368 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 0.977 0.868 – 1.1 0.706 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 0.962 0.912 – 1.02 0.164 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 0.947 0.831 – 1.08 0.412 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 0.984 0.863 – 1.12 0.806 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1 0.939 – 1.07 0.965 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 1.01 0.989 – 1.03 0.338 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 0.986 0.96 – 1.01 0.284 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.976 0.955 – 0.997 0.0245 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 0.999 0.82 – 1.22 0.994 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.02 0.908 – 1.14 0.765 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.938 0.736 – 1.19 0.603 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 1.01 0.977 – 1.04 0.602 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.01 0.994 – 1.03 0.202 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.06 0.935 – 1.2 0.361 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 1.04 0.917 – 1.18 0.531 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.956 0.749 – 1.22 0.719 74 756 all phecode
110.12 Althete's foot Infectious Diseases 1.06 0.888 – 1.26 0.528 141 1410 all phecode
112 Candidiasis Infectious Diseases 1 0.958 – 1.05 0.944 2126 21275 all phecode
117 Mycoses Infectious Diseases 1.03 0.91 – 1.17 0.633 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 0.996 0.85 – 1.17 0.957 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 0.881 0.703 – 1.1 0.269 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 0.85 0.675 – 1.07 0.17 69 689 all phecode
134 Helminthiases Infectious Diseases 1.01 0.838 – 1.22 0.925 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.02 0.829 – 1.25 0.868 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.01 0.878 – 1.17 0.861 205 2050 all phecode
145 Cancer of mouth Neoplasms 0.973 0.896 – 1.06 0.506 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 1.04 0.923 – 1.17 0.541 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.08 0.88 – 1.33 0.448 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 0.962 0.742 – 1.25 0.769 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.984 0.907 – 1.07 0.697 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 0.953 0.837 – 1.08 0.461 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 0.991 0.872 – 1.13 0.889 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 1.04 0.789 – 1.36 0.803 57 570 all phecode
150 Cancer of esophagus Neoplasms 1.04 0.965 – 1.12 0.311 762 7630 all phecode
151 Cancer of stomach Neoplasms 1.02 0.934 – 1.11 0.687 569 5696 all phecode
153 Colorectal cancer Neoplasms 0.998 0.969 – 1.03 0.916 4580 45799 all phecode
153.2 Colon cancer Neoplasms 0.993 0.957 – 1.03 0.689 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1 0.959 – 1.05 0.928 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.872 0.788 – 0.965 0.00818 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.825 0.698 – 0.975 0.0238 158 1580 all phecode
157 Pancreatic cancer Neoplasms 1.01 0.932 – 1.09 0.813 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.02 0.961 – 1.09 0.468 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.01 0.979 – 1.03 0.634 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.985 0.846 – 1.15 0.84 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.918 0.802 – 1.05 0.216 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.16 0.997 – 1.34 0.054 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 0.875 0.672 – 1.14 0.324 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 1.05 1.01 – 1.09 0.0267 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.04 0.998 – 1.09 0.0592 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 1.07 0.967 – 1.18 0.197 437 4364 all phecode
170.1 Bone cancer Neoplasms 1.09 0.915 – 1.31 0.325 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 1.06 0.948 – 1.19 0.301 331 3303 all phecode
172 Skin cancer Neoplasms 1.02 1 – 1.04 0.0162 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.07 1.02 – 1.11 0.00158 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 1.07 1.03 – 1.11 0.00114 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1.02 0.998 – 1.04 0.0784 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 0.922 0.851 – 0.999 0.0468 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.12 0.961 – 1.3 0.151 181 1818 all phecode
174 Breast cancer Neoplasms 1.03 1.01 – 1.05 0.00381 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 1.03 1.01 – 1.05 0.00337 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.02 1.01 – 1.04 0.0122 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.08 0.897 – 1.31 0.4 115 1148 all phecode
175 Acquired absence of breast Neoplasms 1.06 1.02 – 1.11 0.00374 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 1.02 0.979 – 1.07 0.302 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 0.978 0.862 – 1.11 0.731 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.03 0.983 – 1.08 0.221 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 1.07 1.01 – 1.14 0.0166 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 1.17 1.11 – 1.24 5.89e-08 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.18 1.1 – 1.27 1.46e-06 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.17 1.1 – 1.26 5.85e-06 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.08 0.961 – 1.22 0.191 305 3049 all phecode
185 Cancer of prostate Neoplasms 0.983 0.958 – 1.01 0.217 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 0.902 0.82 – 0.991 0.0316 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.83 0.659 – 1.04 0.112 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.912 0.812 – 1.03 0.124 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.04 0.849 – 1.26 0.732 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.02 0.991 – 1.06 0.158 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.02 0.955 – 1.08 0.597 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.01 0.944 – 1.07 0.858 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.12 0.877 – 1.42 0.373 66 660 all phecode
189.2 Cancer of bladder Neoplasms 1.01 0.971 – 1.06 0.547 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.02 0.975 – 1.07 0.403 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.06 0.893 – 1.26 0.493 144 1439 all phecode
190 Cancer of eye Neoplasms 1.09 0.937 – 1.28 0.256 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.15 1.06 – 1.25 0.000467 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1.16 1.07 – 1.27 0.00069 566 5650 all phecode
191.11 Cancer of brain Neoplasms 1.18 1.08 – 1.29 0.000353 525 5240 all phecode
193 Thyroid cancer Neoplasms 1.07 0.959 – 1.2 0.22 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 1.21 0.966 – 1.52 0.0977 95 949 all phecode
195 Cancer, suspected or other Neoplasms 1 0.989 – 1.02 0.561 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.01 0.991 – 1.02 0.421 16267 159497 all phecode
197 Chemotherapy Neoplasms 1.01 0.996 – 1.02 0.178 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 1.01 0.991 – 1.03 0.263 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.998 0.97 – 1.03 0.872 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.02 0.975 – 1.06 0.426 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.01 0.956 – 1.06 0.783 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.03 0.987 – 1.07 0.189 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.03 0.956 – 1.1 0.471 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 0.989 0.947 – 1.03 0.634 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.07 0.92 – 1.25 0.375 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 0.987 0.935 – 1.04 0.633 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 0.993 0.81 – 1.22 0.95 95 950 all phecode
200 Myeloproliferative disease Neoplasms 1.18 1.1 – 1.26 1.14e-06 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 1.19 1.07 – 1.33 0.0011 387 3867 all phecode
201 Hodgkin's disease Neoplasms 0.962 0.846 – 1.09 0.552 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.02 0.981 – 1.07 0.27 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.04 0.988 – 1.09 0.14 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 1.07 0.959 – 1.19 0.225 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 1.03 0.946 – 1.12 0.485 581 5824 all phecode
204 Leukemia Neoplasms 1.04 0.985 – 1.09 0.167 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 1 0.921 – 1.09 0.945 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.15 0.87 – 1.51 0.332 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.999 0.913 – 1.09 0.988 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 1.1 0.997 – 1.2 0.0591 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 1.12 1 – 1.26 0.0416 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.929 0.787 – 1.1 0.39 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 1.04 0.951 – 1.14 0.402 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 0.997 0.982 – 1.01 0.645 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.983 0.921 – 1.05 0.608 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.01 0.981 – 1.04 0.523 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.92 0.825 – 1.03 0.131 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.927 0.828 – 1.04 0.188 318 3187 all phecode
214 Lipoma Neoplasms 1.03 1.01 – 1.06 0.0121 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.05 1.02 – 1.08 0.00293 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.07 1.01 – 1.14 0.0277 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 1.03 1 – 1.05 0.0305 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.959 0.884 – 1.04 0.318 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 0.968 0.89 – 1.05 0.449 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 1.06 1.04 – 1.08 1.24e-07 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 1.06 1.04 – 1.08 2.95e-08 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.13 1.01 – 1.26 0.035 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 1.08 1.03 – 1.14 0.00397 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.03 0.896 – 1.18 0.681 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.905 0.773 – 1.06 0.213 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.04 0.891 – 1.22 0.613 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 1 0.839 – 1.2 0.974 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.878 0.691 – 1.12 0.29 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.11 1.03 – 1.19 0.00758 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.11 1.03 – 1.19 0.00874 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.06 0.814 – 1.38 0.659 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.07 0.943 – 1.22 0.288 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.988 0.921 – 1.06 0.735 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.936 0.807 – 1.08 0.378 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1 0.899 – 1.11 0.99 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.986 0.877 – 1.11 0.819 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.08 1.02 – 1.13 0.00479 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.04 0.999 – 1.09 0.0531 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1 0.922 – 1.09 0.929 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.03 0.964 – 1.09 0.425 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.998 0.909 – 1.1 0.975 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.04 0.964 – 1.13 0.302 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1 0.957 – 1.05 0.873 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 1.04 0.941 – 1.14 0.457 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 0.728 0.593 – 0.893 0.00237 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.02 0.855 – 1.21 0.844 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 1.01 0.997 – 1.03 0.106 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.05 0.988 – 1.12 0.115 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.841 0.691 – 1.02 0.0817 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.01 0.997 – 1.03 0.0954 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 1.05 0.926 – 1.18 0.468 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.13 0.981 – 1.3 0.0903 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.12 0.971 – 1.3 0.118 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.02 0.92 – 1.13 0.708 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 0.996 0.982 – 1.01 0.601 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1 0.962 – 1.04 0.962 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.03 0.899 – 1.18 0.68 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.2 0.949 – 1.53 0.126 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1 0.91 – 1.1 0.993 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.16 0.985 – 1.36 0.0751 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.992 0.977 – 1.01 0.307 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.96 0.783 – 1.18 0.691 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.08 0.936 – 1.25 0.288 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.01 0.946 – 1.08 0.762 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.05 0.955 – 1.15 0.33 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 0.946 0.874 – 1.02 0.171 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.912 0.804 – 1.03 0.152 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.98 0.885 – 1.09 0.695 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.03 0.864 – 1.24 0.718 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.03 0.928 – 1.15 0.55 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.02 0.961 – 1.08 0.549 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.02 0.952 – 1.09 0.59 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.991 0.924 – 1.06 0.795 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1 0.929 – 1.08 0.984 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.811 0.684 – 0.961 0.0153 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.983 0.909 – 1.06 0.669 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.982 0.847 – 1.14 0.81 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.985 0.796 – 1.22 0.888 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.979 0.862 – 1.11 0.741 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.04 0.84 – 1.28 0.733 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.01 0.86 – 1.19 0.904 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.07 0.982 – 1.16 0.127 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1 0.859 – 1.17 0.98 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.02 0.832 – 1.24 0.872 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.985 0.78 – 1.24 0.899 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.1 0.987 – 1.23 0.0862 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.11 0.991 – 1.23 0.0714 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 0.998 0.876 – 1.14 0.971 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.989 0.86 – 1.14 0.878 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 0.971 0.827 – 1.14 0.722 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.964 0.817 – 1.14 0.668 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.06 0.865 – 1.29 0.584 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.11 0.938 – 1.31 0.229 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.06 0.918 – 1.22 0.425 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 0.914 0.69 – 1.21 0.53 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 0.983 0.916 – 1.06 0.639 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.02 0.963 – 1.08 0.473 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.02 0.947 – 1.1 0.606 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1 0.907 – 1.1 0.995 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.831 0.661 – 1.04 0.111 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.945 0.829 – 1.08 0.394 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 1.06 0.951 – 1.19 0.275 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.19 1.06 – 1.35 0.00464 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.17 1.02 – 1.33 0.02 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.16 0.996 – 1.35 0.0563 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 0.847 0.706 – 1.02 0.0746 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.26 0.988 – 1.61 0.0628 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.04 0.885 – 1.22 0.634 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.08 0.908 – 1.29 0.382 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.994 0.983 – 1.01 0.307 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.994 0.983 – 1.01 0.301 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.993 0.982 – 1.01 0.269 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.769 0.592 – 0.999 0.0487 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.07 0.912 – 1.26 0.402 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.953 0.829 – 1.1 0.499 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.02 0.984 – 1.05 0.3 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 1.03 0.992 – 1.07 0.124 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.12 0.927 – 1.36 0.232 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.956 0.882 – 1.04 0.283 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.967 0.888 – 1.05 0.442 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.997 0.954 – 1.04 0.911 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 1.05 0.973 – 1.14 0.2 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 0.955 0.861 – 1.06 0.377 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.97 0.914 – 1.03 0.313 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.02 0.876 – 1.19 0.783 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.01 0.989 – 1.04 0.287 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.03 1 – 1.07 0.0454 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.04 0.915 – 1.19 0.531 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.06 1.01 – 1.11 0.0158 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.01 0.943 – 1.08 0.823 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.04 0.985 – 1.1 0.164 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.02 0.961 – 1.09 0.495 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 1.03 0.965 – 1.09 0.398 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 0.98 0.812 – 1.18 0.838 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 0.97 0.933 – 1.01 0.117 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 1.07 0.97 – 1.18 0.177 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 0.955 0.798 – 1.14 0.619 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 0.997 0.932 – 1.07 0.931 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.938 0.843 – 1.04 0.242 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.954 0.835 – 1.09 0.494 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.794 0.613 – 1.03 0.0827 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.01 0.995 – 1.03 0.153 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 1.01 0.995 – 1.04 0.146 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 0.879 0.703 – 1.1 0.256 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.11 0.855 – 1.44 0.432 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.956 0.841 – 1.09 0.494 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 0.942 0.818 – 1.09 0.41 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.871 0.733 – 1.03 0.114 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.08 0.951 – 1.24 0.223 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 1 0.977 – 1.02 0.961 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1 0.976 – 1.02 0.978 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.04 0.945 – 1.15 0.417 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 1.01 0.948 – 1.07 0.809 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 1 0.939 – 1.06 0.997 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 1 0.929 – 1.08 0.981 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.976 0.842 – 1.13 0.752 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 0.986 0.85 – 1.14 0.852 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 0.842 0.646 – 1.1 0.205 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 0.9 0.766 – 1.06 0.201 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 0.885 0.683 – 1.15 0.357 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.915 0.735 – 1.14 0.43 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.11 0.928 – 1.32 0.257 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.04 0.852 – 1.27 0.695 103 1059 all phecode
284 Aplastic anemia Hematopoietic 1.05 0.949 – 1.16 0.362 435 4357 all phecode
285 Other anemias Hematopoietic 1 0.986 – 1.02 0.635 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.07 0.939 – 1.21 0.323 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.04 0.962 – 1.12 0.326 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.03 0.929 – 1.14 0.598 414 4147 all phecode
286 Coagulation defects Hematopoietic 1.05 0.984 – 1.13 0.137 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 1.03 0.937 – 1.14 0.524 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 1.01 0.821 – 1.25 0.908 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.03 0.914 – 1.16 0.611 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.06 0.825 – 1.36 0.65 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.837 0.672 – 1.04 0.113 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.13 1.01 – 1.26 0.0263 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.03 0.98 – 1.08 0.239 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.12 0.928 – 1.34 0.243 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 1.01 0.778 – 1.32 0.929 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 1.03 0.977 – 1.08 0.287 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.09 0.987 – 1.2 0.0895 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.08 0.854 – 1.37 0.52 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 1.05 1.01 – 1.08 0.00672 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 1.05 1.01 – 1.09 0.00961 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 1.05 1.01 – 1.09 0.00899 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 1.08 0.849 – 1.37 0.53 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.02 0.952 – 1.1 0.549 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.06 0.94 – 1.19 0.348 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 1.02 0.984 – 1.07 0.247 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 1.12 1.02 – 1.23 0.019 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.02 0.904 – 1.14 0.792 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 0.929 0.756 – 1.14 0.481 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.964 0.92 – 1.01 0.121 1929 19281 all phecode
290.1 Dementias Mental Disorders 0.955 0.895 – 1.02 0.162 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 0.918 0.831 – 1.01 0.0945 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 0.952 0.825 – 1.1 0.503 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.945 0.872 – 1.02 0.166 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.07 0.839 – 1.38 0.57 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.03 0.96 – 1.11 0.403 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.05 0.88 – 1.25 0.607 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.03 0.908 – 1.16 0.679 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 1.04 0.94 – 1.15 0.464 436 4376 all phecode
292 Neurological disorders Mental Disorders 0.997 0.968 – 1.03 0.871 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1 0.953 – 1.06 0.864 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 1.08 0.922 – 1.26 0.354 190 1907 all phecode
292.3 Memory loss Mental Disorders 0.966 0.894 – 1.04 0.386 696 6978 all phecode
292.4 Altered mental status Mental Disorders 1.01 0.965 – 1.05 0.687 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 0.99 0.883 – 1.11 0.859 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 0.966 0.924 – 1.01 0.131 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.08 1 – 1.15 0.0377 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.999 0.931 – 1.07 0.985 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 0.989 0.908 – 1.08 0.796 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 1.1 0.945 – 1.28 0.221 178 1780 all phecode
295.3 Psychosis Mental Disorders 1.08 0.926 – 1.27 0.313 169 1710 all phecode
296 Mood disorders Mental Disorders 1.01 0.99 – 1.03 0.381 12372 123822 all phecode
296.1 Bipolar Mental Disorders 0.994 0.934 – 1.06 0.851 1059 10599 all phecode
296.2 Depression Mental Disorders 1.01 0.991 – 1.03 0.288 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 0.966 0.869 – 1.07 0.516 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.954 0.851 – 1.07 0.422 311 3070 all phecode
300 Anxiety disorders Mental Disorders 1.01 0.982 – 1.03 0.618 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 1.01 0.981 – 1.03 0.612 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 0.87 0.739 – 1.02 0.0938 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.993 0.92 – 1.07 0.85 707 7065 all phecode
300.13 Phobia Mental Disorders 1.02 0.936 – 1.12 0.597 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.09 0.91 – 1.3 0.359 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 1.39 1.04 – 1.86 0.0263 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 0.91 0.762 – 1.09 0.293 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.01 0.831 – 1.22 0.947 113 1129 all phecode
301 Personality disorders Mental Disorders 1.02 0.911 – 1.14 0.745 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.965 0.799 – 1.17 0.71 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.888 0.791 – 0.997 0.0436 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.964 0.877 – 1.06 0.453 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 0.97 0.87 – 1.08 0.582 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 0.918 0.769 – 1.1 0.341 123 1229 all phecode
304 Adjustment reaction Mental Disorders 1.1 0.975 – 1.24 0.12 293 2936 all phecode
305.2 Eating disorder Mental Disorders 1.07 0.858 – 1.33 0.554 90 900 all phecode
306 Other mental disorder Mental Disorders 1.01 0.996 – 1.02 0.187 28056 230087 all phecode
306.9 Tension headache Mental Disorders 0.962 0.856 – 1.08 0.51 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 0.909 0.72 – 1.15 0.425 76 770 all phecode
313.3 Autism Mental Disorders 0.977 0.734 – 1.3 0.874 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 1.06 0.947 – 1.18 0.319 351 3517 all phecode
315.1 Learning disorder Mental Disorders 0.959 0.815 – 1.13 0.611 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 1.06 0.852 – 1.33 0.59 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 1.01 0.978 – 1.03 0.679 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.845 0.651 – 1.1 0.209 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 1 0.983 – 1.02 0.912 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 0.997 0.976 – 1.02 0.791 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 0.946 0.882 – 1.02 0.123 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 1.01 0.99 – 1.02 0.488 19359 185465 all phecode
320 Meningitis Neurological 0.982 0.891 – 1.08 0.709 444 4447 all phecode
323 Encephalitis Neurological 1.05 0.939 – 1.17 0.395 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 1.13 0.891 – 1.44 0.306 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 0.936 0.834 – 1.05 0.265 292 2916 all phecode
327 Sleep disorders Neurological 0.992 0.934 – 1.05 0.793 1164 11659 all phecode
327.3 Sleep apnea Neurological 0.984 0.954 – 1.01 0.31 4428 44318 all phecode
327.4 Insomnia Neurological 1.14 0.971 – 1.34 0.11 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 1.25 1.05 – 1.5 0.0131 136 1390 all phecode
331 Other cerebral degenerations Neurological 0.978 0.92 – 1.04 0.471 1142 11416 all phecode
331.1 Hydrocephalus Neurological 0.995 0.907 – 1.09 0.921 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 0.989 0.895 – 1.09 0.823 430 4298 all phecode
332 Parkinson's disease Neurological 0.975 0.917 – 1.04 0.416 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.01 0.94 – 1.08 0.832 894 8954 all phecode
333.1 Essential tremor Neurological 0.948 0.828 – 1.09 0.44 216 2157 all phecode
333.2 Myoclonus Neurological 0.953 0.775 – 1.17 0.646 96 958 all phecode
333.4 Torsion dystonia Neurological 1 0.879 – 1.14 0.998 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 0.986 0.94 – 1.03 0.57 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 0.989 0.818 – 1.2 0.909 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 1.07 0.936 – 1.22 0.332 245 2446 all phecode
335 Multiple sclerosis Neurological 0.964 0.911 – 1.02 0.194 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 0.969 0.853 – 1.1 0.624 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 0.817 0.645 – 1.03 0.0937 72 719 all phecode
338 Pain Neurological 1.06 0.984 – 1.14 0.127 768 7692 all phecode
338.1 Acute pain Neurological 1.02 0.92 – 1.13 0.707 394 3937 all phecode
338.2 Chronic pain Neurological 1.09 0.978 – 1.21 0.122 380 3817 all phecode
339 Other headache syndromes Neurological 1.01 0.985 – 1.03 0.509 7819 78241 all phecode
340 Migraine Neurological 1.02 0.984 – 1.06 0.259 2860 28602 all phecode
340.1 Migrain with aura Neurological 0.979 0.852 – 1.12 0.761 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.991 0.873 – 1.12 0.886 252 2535 all phecode
342 Hemiplegia Neurological 1.03 0.974 – 1.08 0.323 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 0.968 0.82 – 1.14 0.696 145 1450 all phecode
344 Other paralytic syndromes Neurological 0.991 0.915 – 1.07 0.818 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.995 0.966 – 1.02 0.715 5023 50270 all phecode
345.1 Epilepsy Neurological 0.945 0.881 – 1.01 0.117 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 0.965 0.875 – 1.06 0.47 439 4385 all phecode
345.12 Partial epilepsy Neurological 0.909 0.802 – 1.03 0.13 277 2776 all phecode
345.3 Convulsions Neurological 0.965 0.924 – 1.01 0.102 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.17 0.982 – 1.39 0.0796 144 1438 all phecode
348 Other conditions of brain Neurological 1.01 0.935 – 1.08 0.865 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.01 0.893 – 1.15 0.863 268 2678 all phecode
348.4 Cerebral cysts Neurological 1.08 0.908 – 1.29 0.371 133 1350 all phecode
348.7 Coma Neurological 1.05 0.937 – 1.17 0.421 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.04 0.908 – 1.18 0.593 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 1.1 0.986 – 1.22 0.0902 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.01 0.907 – 1.13 0.8 342 3414 all phecode
350 Abnormal movement Neurological 0.984 0.946 – 1.02 0.431 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 0.908 0.848 – 0.974 0.00671 887 8852 all phecode
350.2 Abnormality of gait Neurological 0.999 0.95 – 1.05 0.977 1596 15969 all phecode
350.3 Lack of coordination Neurological 1.05 0.941 – 1.17 0.394 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.914 0.694 – 1.2 0.524 54 540 all phecode
351 Other peripheral nerve disorders Neurological 0.995 0.977 – 1.01 0.595 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 1.03 0.972 – 1.09 0.332 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.09 0.994 – 1.21 0.0674 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.01 0.938 – 1.08 0.87 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 0.98 0.923 – 1.04 0.522 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 1.01 0.837 – 1.23 0.891 114 1138 all phecode
353.2 Nerve root lesions Neurological 1.09 0.828 – 1.44 0.531 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.963 0.817 – 1.14 0.654 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.02 0.969 – 1.08 0.403 1361 13648 all phecode
358 Myoneural disorders Neurological 0.976 0.847 – 1.12 0.737 211 2109 all phecode
358.1 Myasthenia gravis Neurological 0.96 0.826 – 1.12 0.594 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.997 0.907 – 1.09 0.945 465 4646 all phecode
359.1 Muscular dystrophies Neurological 0.879 0.733 – 1.05 0.165 122 1219 all phecode
359.2 Myopathy Neurological 1.04 0.936 – 1.16 0.45 360 3597 all phecode
360 Disorders of the globe Sense Organs 0.989 0.887 – 1.1 0.843 337 3367 all phecode
360.2 Progressive myopia Sense Organs 0.928 0.819 – 1.05 0.242 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 1.01 0.978 – 1.05 0.46 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.997 0.943 – 1.05 0.904 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 1.03 0.816 – 1.29 0.825 68 680 all phecode
362 Other retinal disorders Sense Organs 0.998 0.965 – 1.03 0.892 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.03 0.989 – 1.08 0.139 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.03 0.989 – 1.08 0.144 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.02 0.865 – 1.2 0.839 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 1 0.817 – 1.23 0.969 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.968 0.903 – 1.04 0.362 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 1.08 0.927 – 1.27 0.316 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.923 0.739 – 1.15 0.483 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.02 0.845 – 1.24 0.823 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.96 0.817 – 1.13 0.616 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 0.855 0.666 – 1.1 0.219 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.974 0.898 – 1.06 0.518 647 6485 all phecode
364.1 Corneal opacity Sense Organs 0.952 0.769 – 1.18 0.655 90 910 all phecode
364.2 Corneal edema Sense Organs 0.833 0.673 – 1.03 0.0921 79 800 all phecode
364.4 Corneal degenerations Sense Organs 1.08 0.933 – 1.26 0.296 201 2017 all phecode
364.41 Keratoconus Sense Organs 0.919 0.741 – 1.14 0.439 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 0.935 0.813 – 1.07 0.343 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.996 0.808 – 1.23 0.972 100 1000 all phecode
365 Glaucoma Sense Organs 1.01 0.981 – 1.04 0.464 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 1.02 0.96 – 1.09 0.494 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.02 0.956 – 1.08 0.577 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.01 0.938 – 1.1 0.726 698 6996 all phecode
366 Cataract Sense Organs 0.991 0.977 – 1.01 0.24 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 1.13 0.891 – 1.44 0.31 69 700 all phecode
366.2 Senile cataract Sense Organs 0.995 0.973 – 1.02 0.67 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 1.09 0.885 – 1.33 0.431 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.963 0.924 – 1 0.0784 2408 24092 all phecode
367.1 Myopia Sense Organs 0.969 0.915 – 1.03 0.292 1251 12519 all phecode
367.2 Astigmatism Sense Organs 0.843 0.729 – 0.974 0.0207 190 1899 all phecode
367.8 Hypermetropia Sense Organs 0.986 0.865 – 1.12 0.835 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 0.974 0.904 – 1.05 0.501 719 7198 all phecode
368 Visual disturbances Sense Organs 0.997 0.961 – 1.04 0.894 2962 29648 all phecode
368.1 Amblyopia Sense Organs 0.986 0.902 – 1.08 0.76 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.01 0.932 – 1.09 0.873 727 7288 all phecode
368.3 Anisometropia Sense Organs 0.908 0.771 – 1.07 0.248 154 1548 all phecode
368.4 Visual field defects Sense Organs 0.952 0.851 – 1.07 0.393 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 1 0.925 – 1.09 0.932 612 6115 all phecode
369 Infection of the eye Sense Organs 1.02 0.933 – 1.12 0.663 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 0.988 0.827 – 1.18 0.896 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 1.08 0.939 – 1.25 0.273 213 2128 all phecode
370 Keratitis Sense Organs 1.08 0.952 – 1.22 0.241 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 1.06 0.89 – 1.26 0.518 141 1408 all phecode
371 Inflammation of the eye Sense Organs 0.995 0.958 – 1.03 0.79 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.981 0.894 – 1.08 0.679 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 0.995 0.954 – 1.04 0.824 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 0.985 0.914 – 1.06 0.688 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 1.01 0.987 – 1.04 0.312 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 1 0.943 – 1.07 0.909 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 1.03 0.977 – 1.08 0.313 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 0.998 0.955 – 1.04 0.919 2204 22031 all phecode
375.2 Epiphora Sense Organs 1.04 0.973 – 1.12 0.239 898 8969 all phecode
376 Disorders of the orbit Sense Organs 0.895 0.718 – 1.12 0.322 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.03 0.923 – 1.15 0.613 361 3618 all phecode
377.1 Optic atrophy Sense Organs 1.11 0.849 – 1.46 0.438 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.04 0.872 – 1.25 0.639 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.01 0.956 – 1.07 0.732 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1 0.939 – 1.07 0.905 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.94 0.819 – 1.08 0.383 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 1.02 0.896 – 1.15 0.806 275 2755 all phecode
379 Other disorders of eye Sense Organs 0.992 0.959 – 1.03 0.655 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 0.981 0.927 – 1.04 0.49 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.979 0.933 – 1.03 0.374 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 0.889 0.698 – 1.13 0.344 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.03 0.931 – 1.15 0.536 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.03 0.88 – 1.21 0.691 169 1690 all phecode
380 Disorders of external ear Sense Organs 1.01 0.933 – 1.1 0.774 642 6413 all phecode
380.1 Otitis externa Sense Organs 0.935 0.856 – 1.02 0.132 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 1.02 0.919 – 1.14 0.659 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.982 0.94 – 1.03 0.407 2150 21493 all phecode
381.1 Otitis media Sense Organs 0.985 0.938 – 1.03 0.532 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.959 0.894 – 1.03 0.247 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 0.97 0.839 – 1.12 0.682 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 0.95 0.813 – 1.11 0.516 171 1709 all phecode
381.9 Otorrhea Sense Organs 0.931 0.824 – 1.05 0.257 281 2807 all phecode
382 Otalgia Sense Organs 1.08 0.961 – 1.22 0.194 308 3084 all phecode
383 Otosclerosis Sense Organs 1.03 0.915 – 1.15 0.651 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.03 0.976 – 1.1 0.25 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.05 0.983 – 1.12 0.152 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.03 0.961 – 1.11 0.373 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 1 0.924 – 1.09 0.931 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.11 0.967 – 1.27 0.139 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1 0.952 – 1.05 0.988 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 0.964 0.885 – 1.05 0.392 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 1.02 0.914 – 1.13 0.766 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 1.01 0.938 – 1.09 0.791 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.01 0.976 – 1.04 0.711 4582 45806 all phecode
388 Other disorders of ear Sense Organs 1.01 0.87 – 1.16 0.927 202 2017 all phecode
389 Hearing loss Sense Organs 0.997 0.966 – 1.03 0.851 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.935 0.851 – 1.03 0.158 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 0.849 0.773 – 0.934 0.000729 450 4497 all phecode
389.4 Tinnitus Sense Organs 1.03 0.938 – 1.13 0.549 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.02 0.986 – 1.05 0.293 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 1 0.966 – 1.04 0.854 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 1.04 0.978 – 1.1 0.22 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.03 0.963 – 1.09 0.427 1058 10566 all phecode
395 Heart valve disorders Circulatory System 1.01 0.976 – 1.04 0.656 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.01 0.969 – 1.05 0.74 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.982 0.871 – 1.11 0.763 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.16 0.951 – 1.42 0.142 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.852 0.696 – 1.04 0.12 97 970 all phecode
395.6 Heart valve replaced Circulatory System 1 0.951 – 1.06 0.893 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 0.987 0.927 – 1.05 0.695 1048 10468 all phecode
401 Hypertension Circulatory System 1.01 1 – 1.02 0.0317 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 1.01 1 – 1.02 0.0315 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.03 0.979 – 1.08 0.287 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 0.965 0.866 – 1.08 0.518 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.04 0.988 – 1.1 0.133 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 1.02 0.86 – 1.22 0.799 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 0.977 0.926 – 1.03 0.398 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 0.996 0.984 – 1.01 0.482 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.977 0.949 – 1 0.104 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 0.979 0.961 – 0.998 0.0301 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 0.994 0.977 – 1.01 0.445 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 0.984 0.97 – 0.999 0.0349 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.05 0.968 – 1.13 0.255 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.991 0.974 – 1.01 0.278 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.01 0.952 – 1.07 0.756 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 0.972 0.927 – 1.02 0.248 1823 18228 all phecode
414.2 ASCVD Circulatory System 1.06 0.838 – 1.33 0.644 72 719 all phecode
415 Pulmonary heart disease Circulatory System 1 0.971 – 1.03 0.917 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.14 0.891 – 1.45 0.302 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.983 0.904 – 1.07 0.687 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.01 0.917 – 1.11 0.822 448 4475 all phecode
416 Cardiomegaly Circulatory System 0.987 0.949 – 1.03 0.516 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 0.988 0.976 – 1 0.0515 28599 270106 all phecode
418.1 Precordial pain Circulatory System 0.976 0.943 – 1.01 0.164 3551 35541 all phecode
420 Carditis Circulatory System 1.01 0.968 – 1.06 0.578 2106 21053 all phecode
420.1 Myocarditis Circulatory System 1.03 0.858 – 1.23 0.763 127 1267 all phecode
420.2 Pericarditis Circulatory System 1 0.948 – 1.06 0.91 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 1.04 0.909 – 1.19 0.554 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 1.1 0.899 – 1.34 0.361 113 1129 all phecode
420.3 Endocarditis Circulatory System 1.01 0.935 – 1.09 0.799 719 7194 all phecode
425 Cardiomyopathy Circulatory System 0.997 0.942 – 1.06 0.926 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.989 0.933 – 1.05 0.708 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.951 0.8 – 1.13 0.566 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.949 0.808 – 1.12 0.527 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 1.12 0.861 – 1.47 0.39 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 1.01 0.988 – 1.04 0.314 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.03 0.99 – 1.08 0.134 2114 21162 all phecode
426.21 First degree AV block Circulatory System 1.04 0.978 – 1.11 0.2 986 9867 all phecode
426.23 Second degree AV block Circulatory System 0.946 0.858 – 1.04 0.261 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.07 0.983 – 1.17 0.119 587 5868 all phecode
426.25 Other heart block Circulatory System 1.03 0.862 – 1.23 0.745 131 1318 all phecode
426.3 Bundle branch block Circulatory System 0.993 0.958 – 1.03 0.684 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 1 0.951 – 1.06 0.911 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 0.98 0.933 – 1.03 0.409 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.892 0.783 – 1.02 0.0886 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.03 0.791 – 1.34 0.827 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.04 0.998 – 1.09 0.0599 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.03 0.986 – 1.08 0.189 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 1.01 1 – 1.03 0.0361 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.02 0.987 – 1.06 0.203 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.03 0.986 – 1.07 0.183 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.991 0.927 – 1.06 0.794 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.01 0.992 – 1.03 0.274 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.977 0.943 – 1.01 0.211 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.982 0.926 – 1.04 0.554 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.984 0.881 – 1.1 0.781 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 0.988 0.926 – 1.05 0.724 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.03 0.961 – 1.1 0.43 952 9541 all phecode
427.6 Premature beats Circulatory System 1.05 0.957 – 1.15 0.314 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 0.997 0.831 – 1.2 0.97 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 1.06 1.02 – 1.11 0.00868 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.966 0.872 – 1.07 0.509 402 4029 all phecode
427.9 Palpitations Circulatory System 1.02 0.985 – 1.05 0.277 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.989 0.962 – 1.02 0.408 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 0.975 0.933 – 1.02 0.26 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 1 0.97 – 1.03 0.956 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.04 0.967 – 1.13 0.267 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 1.12 0.857 – 1.45 0.414 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.04 0.949 – 1.14 0.41 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.06 0.914 – 1.23 0.45 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 1.06 1.01 – 1.12 0.013 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.09 1.01 – 1.17 0.0246 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1.08 1 – 1.17 0.0399 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 1.01 0.893 – 1.15 0.854 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 1 0.983 – 1.03 0.684 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.979 0.922 – 1.04 0.481 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.02 0.891 – 1.17 0.752 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1 0.969 – 1.03 0.997 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1 0.951 – 1.05 0.984 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 0.991 0.954 – 1.03 0.628 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 0.997 0.954 – 1.04 0.905 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 1.12 1.01 – 1.25 0.0308 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1 0.946 – 1.06 0.945 1279 12783 all phecode
440 Atherosclerosis Circulatory System 1.03 0.971 – 1.08 0.364 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.09 0.902 – 1.32 0.372 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.06 0.989 – 1.14 0.0972 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 0.899 0.8 – 1.01 0.0725 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.04 0.957 – 1.13 0.348 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.06 0.933 – 1.19 0.39 283 2827 all phecode
442 Other aneurysm Circulatory System 1.05 1 – 1.1 0.0352 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 1.04 0.984 – 1.1 0.169 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.992 0.928 – 1.06 0.82 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.02 0.832 – 1.24 0.874 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.05 0.901 – 1.23 0.506 169 1696 all phecode
442.4 Arterial dissection Circulatory System 1.22 0.93 – 1.6 0.151 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.11 0.963 – 1.29 0.147 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 1.01 0.978 – 1.04 0.509 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 1.04 0.977 – 1.1 0.231 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.05 0.947 – 1.17 0.346 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.01 0.978 – 1.05 0.5 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.993 0.954 – 1.03 0.733 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 0.997 0.932 – 1.07 0.935 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.02 0.934 – 1.11 0.663 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.01 0.938 – 1.08 0.833 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 0.929 0.802 – 1.08 0.329 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 0.992 0.894 – 1.1 0.878 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 0.988 0.866 – 1.13 0.854 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.01 0.956 – 1.07 0.681 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 1.03 0.964 – 1.11 0.348 868 8712 all phecode
448 Disease of capillaries Circulatory System 0.921 0.778 – 1.09 0.342 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.03 0.95 – 1.11 0.515 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.979 0.948 – 1.01 0.203 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.981 0.948 – 1.01 0.26 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 1.01 0.929 – 1.11 0.768 564 5645 all phecode
454 Varicose veins Circulatory System 1.01 0.992 – 1.03 0.253 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1.01 0.988 – 1.03 0.465 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.03 0.953 – 1.12 0.417 624 6325 all phecode
455 Hemorrhoids Circulatory System 1.01 0.992 – 1.02 0.444 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.957 0.828 – 1.11 0.551 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.815 0.662 – 1 0.0545 97 967 all phecode
458 Hypotension Circulatory System 0.993 0.966 – 1.02 0.606 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 1.04 0.979 – 1.1 0.219 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.06 0.923 – 1.21 0.417 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 0.977 0.944 – 1.01 0.186 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 1 0.987 – 1.02 0.733 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 0.838 0.709 – 0.991 0.0384 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 1 0.988 – 1.02 0.61 16103 159422 all phecode
464 Acute sinusitis Respiratory 0.926 0.803 – 1.07 0.288 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.02 0.978 – 1.07 0.34 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 1.05 0.982 – 1.13 0.143 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.08 0.919 – 1.27 0.348 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1 0.97 – 1.03 0.996 4654 46553 all phecode
471 Nasal polyps Respiratory 0.988 0.953 – 1.02 0.509 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.05 0.985 – 1.13 0.127 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1.01 0.967 – 1.05 0.718 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 1.05 0.856 – 1.28 0.663 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.898 0.795 – 1.01 0.0831 264 2647 all phecode
473.4 Voice disturbance Respiratory 1.02 0.957 – 1.08 0.564 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 0.999 0.951 – 1.05 0.961 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 1.02 0.934 – 1.11 0.678 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.968 0.911 – 1.03 0.306 1122 11199 all phecode
475 Chronic sinusitis Respiratory 0.973 0.934 – 1.01 0.181 2589 25882 all phecode
476 Allergic rhinitis Respiratory 0.999 0.938 – 1.06 0.975 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 0.999 0.958 – 1.04 0.949 2447 24452 all phecode
478 Throat pain Respiratory 0.981 0.883 – 1.09 0.718 377 3789 all phecode
479 Other upper respiratory disease Respiratory 1 0.969 – 1.03 0.984 4074 40737 all phecode
480 Pneumonia Respiratory 1 0.985 – 1.03 0.633 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 1.02 0.99 – 1.04 0.247 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.02 0.99 – 1.04 0.23 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 0.875 0.71 – 1.08 0.207 93 929 all phecode
480.2 Viral pneumonia Respiratory 1.12 0.875 – 1.42 0.378 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.909 0.745 – 1.11 0.352 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1 0.931 – 1.08 0.955 794 7951 all phecode
481 Influenza Respiratory 0.98 0.874 – 1.1 0.735 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.01 0.877 – 1.17 0.861 193 1930 all phecode
495 Asthma Respiratory 0.999 0.986 – 1.01 0.867 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 1.18 1.03 – 1.34 0.0167 250 2510 all phecode
496 Chronic airway obstruction Respiratory 0.989 0.969 – 1.01 0.282 10424 101546 all phecode
496.1 Emphysema Respiratory 0.956 0.91 – 1 0.0692 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 0.987 0.95 – 1.03 0.5 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1 0.964 – 1.04 0.903 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 0.951 0.908 – 0.997 0.0376 1885 18859 all phecode
497 Bronchitis Respiratory 1.03 0.946 – 1.12 0.525 626 6267 all phecode
500 Lung disease due to external agents Respiratory 0.952 0.862 – 1.05 0.327 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.972 0.784 – 1.2 0.792 79 784 all phecode
500.2 Pneumoconiosis Respiratory 0.947 0.831 – 1.08 0.42 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.01 0.928 – 1.09 0.89 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.913 0.854 – 0.977 0.00808 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.06 0.969 – 1.17 0.193 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.941 0.843 – 1.05 0.28 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.02 0.781 – 1.34 0.874 61 610 all phecode
506 Empyema and pneumothorax Respiratory 1.01 0.954 – 1.08 0.645 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 0.999 0.974 – 1.02 0.935 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.97 0.926 – 1.02 0.192 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.01 0.97 – 1.05 0.631 2599 26031 all phecode
509.1 Respiratory failure Respiratory 1.03 0.983 – 1.08 0.226 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 1.02 0.972 – 1.07 0.427 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 0.904 0.767 – 1.07 0.233 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.942 0.848 – 1.05 0.263 386 3863 all phecode
510 Other diseases of lung Respiratory 0.992 0.92 – 1.07 0.823 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 0.992 0.971 – 1.01 0.456 9031 90349 all phecode
512.1 Wheezing Respiratory 0.934 0.818 – 1.07 0.307 220 2196 all phecode
512.2 Painful respiration Respiratory 0.941 0.815 – 1.09 0.403 207 2075 all phecode
512.7 Shortness of breath Respiratory 0.993 0.966 – 1.02 0.587 5842 58498 all phecode
512.8 Cough Respiratory 1 0.964 – 1.04 0.926 2866 28642 all phecode
512.9 Other dyspnea Respiratory 1 0.937 – 1.07 0.942 914 9124 all phecode
513 Respiratory abnormalities Respiratory 1.01 0.93 – 1.1 0.803 611 6112 all phecode
513.3 Hypoventilation Respiratory 0.933 0.747 – 1.17 0.541 83 830 all phecode
513.4 Hyperventilation Respiratory 1.11 0.975 – 1.25 0.116 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 0.827 0.703 – 0.973 0.0218 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 1 0.962 – 1.04 0.902 2465 24673 all phecode
516 Abnormal sputum Respiratory 1.02 0.977 – 1.07 0.35 2132 21335 all phecode
516.1 Hemoptysis Respiratory 1.02 0.975 – 1.07 0.379 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.984 0.963 – 1.01 0.135 9366 93681 all phecode
519.2 Respiratory complications Respiratory 1.01 0.902 – 1.13 0.842 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.983 0.962 – 1 0.128 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.07 0.951 – 1.21 0.25 303 3049 all phecode
520 Disorders of tooth development Digestive 0.981 0.937 – 1.03 0.412 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.11 0.83 – 1.49 0.478 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 0.985 0.944 – 1.03 0.471 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 0.982 0.946 – 1.02 0.336 3016 30245 all phecode
521.1 Dental caries Digestive 0.981 0.946 – 1.02 0.321 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.03 0.98 – 1.08 0.246 1774 17750 all phecode
522.5 Periapical abscess Digestive 0.991 0.934 – 1.05 0.764 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 1.02 0.968 – 1.07 0.496 1681 16812 all phecode
523.1 Gingivitis Digestive 0.979 0.804 – 1.19 0.831 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.02 0.963 – 1.09 0.466 1165 11650 all phecode
523.31 Acute periodontitis Digestive 0.986 0.911 – 1.07 0.73 666 6667 all phecode
523.32 Chronic periodontitis Digestive 1.01 0.93 – 1.11 0.742 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.04 0.928 – 1.16 0.51 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.964 0.859 – 1.08 0.532 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.985 0.946 – 1.02 0.442 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.1 0.845 – 1.42 0.49 72 720 all phecode
526 Diseases of the jaws Digestive 1 0.937 – 1.07 0.937 928 9279 all phecode
526.1 Cysts of the jaws Digestive 0.938 0.838 – 1.05 0.27 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.08 0.834 – 1.41 0.549 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.11 0.968 – 1.27 0.138 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.08 0.945 – 1.24 0.248 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.968 0.795 – 1.18 0.744 110 1098 all phecode
526.9 Jaw disease NOS Digestive 1.03 0.902 – 1.18 0.648 233 2329 all phecode
527 Diseases of the salivary glands Digestive 1.02 0.944 – 1.1 0.604 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.14 0.902 – 1.43 0.276 84 838 all phecode
527.2 Sialoadenitis Digestive 1.02 0.917 – 1.14 0.69 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 0.974 0.761 – 1.25 0.834 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.01 0.842 – 1.22 0.886 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.02 0.986 – 1.05 0.251 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 1.02 0.931 – 1.12 0.645 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.02 0.917 – 1.13 0.761 389 3884 all phecode
528.12 Oral aphthae Digestive 1.06 0.849 – 1.33 0.59 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.04 0.891 – 1.21 0.631 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 0.996 0.831 – 1.19 0.962 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 0.989 0.801 – 1.22 0.921 94 940 all phecode
528.5 Diseases of lips Digestive 1.05 0.971 – 1.14 0.214 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.07 0.952 – 1.21 0.248 308 3079 all phecode
528.7 Sialolithiasis Digestive 1.01 0.895 – 1.13 0.924 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 0.993 0.937 – 1.05 0.824 1232 12312 all phecode
529.1 Glossitis Digestive 1 0.891 – 1.13 0.981 299 2986 all phecode
530 Diseases of esophagus Digestive 1 0.99 – 1.01 0.768 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1 0.988 – 1.01 0.99 31253 272429 all phecode
530.11 GERD Digestive 1 0.989 – 1.02 0.738 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 0.997 0.969 – 1.03 0.839 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 0.99 0.97 – 1.01 0.326 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.986 0.938 – 1.04 0.589 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.05 0.998 – 1.1 0.0624 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 1.08 0.991 – 1.17 0.0815 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.07 0.905 – 1.26 0.44 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.05 0.934 – 1.17 0.441 341 3416 all phecode
530.9 Heartburn Digestive 1 0.957 – 1.05 0.965 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1 0.977 – 1.03 0.952 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.01 0.925 – 1.09 0.905 637 6374 all phecode
531.2 Gastric ulcer Digestive 1.01 0.98 – 1.05 0.464 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 0.985 0.948 – 1.02 0.416 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.04 0.944 – 1.15 0.417 427 4268 all phecode
532 Dysphagia Digestive 1 0.978 – 1.03 0.801 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 0.996 0.984 – 1.01 0.519 28078 261548 all phecode
535.1 Acute gastritis Digestive 1.02 0.959 – 1.08 0.577 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 0.936 0.842 – 1.04 0.215 370 3687 all phecode
535.6 Duodenitis Digestive 0.983 0.96 – 1.01 0.16 7592 75928 all phecode
535.8 Other specified gastritis Digestive 1.01 0.985 – 1.03 0.482 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.01 0.836 – 1.21 0.942 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.06 0.938 – 1.21 0.337 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 0.991 0.957 – 1.03 0.619 3391 33907 all phecode
540 Appendiceal conditions Digestive 1.02 0.979 – 1.05 0.398 3088 30890 all phecode
540.1 Appendicitis Digestive 1.02 0.979 – 1.06 0.377 2895 28963 all phecode
540.11 Acute appendicitis Digestive 1.02 0.978 – 1.06 0.379 2601 26019 all phecode
550 Abdominal hernia Digestive 0.989 0.979 – 0.999 0.0277 45429 282640 all phecode
550.1 Inguinal hernia Digestive 1.01 0.99 – 1.02 0.459 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 0.981 0.969 – 0.994 0.0032 26494 238953 all phecode
550.3 Femoral hernia Digestive 1.01 0.929 – 1.09 0.891 651 6504 all phecode
550.4 Umbilical hernia Digestive 0.964 0.932 – 0.997 0.0324 3705 37072 all phecode
550.5 Ventral hernia Digestive 1.03 0.994 – 1.07 0.104 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.01 0.975 – 1.04 0.729 4444 44442 all phecode
555.1 Regional enteritis Digestive 1.03 0.977 – 1.08 0.293 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 1 0.964 – 1.04 0.986 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.01 0.922 – 1.1 0.877 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 1 0.941 – 1.07 0.94 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 1.01 0.932 – 1.09 0.826 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.862 0.768 – 0.969 0.0124 299 2987 all phecode
557.1 Celiac disease Digestive 0.989 0.943 – 1.04 0.648 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 1.02 1 – 1.03 0.0447 15492 155105 all phecode
559 Ileostomy status Digestive 0.981 0.933 – 1.03 0.454 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.02 0.984 – 1.05 0.322 3936 39337 all phecode
560.1 Paralytic ileus Digestive 0.986 0.901 – 1.08 0.756 523 5231 all phecode
560.2 Impaction of intestine Digestive 1.06 0.93 – 1.2 0.404 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 1 0.934 – 1.08 0.93 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 1.01 0.976 – 1.05 0.538 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 0.983 0.967 – 0.999 0.0369 15772 157686 all phecode
561.1 Diarrhea Digestive 1 0.911 – 1.1 0.969 466 4653 all phecode
561.2 Flatulence Digestive 0.986 0.937 – 1.04 0.569 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 1 0.99 – 1.02 0.635 26714 211692 all phecode
562.1 Diverticulosis Digestive 1 0.99 – 1.02 0.678 26672 211642 all phecode
563 Constipation Digestive 0.994 0.974 – 1.01 0.577 10314 103140 all phecode
564 Functional digestive disorders Digestive 1 0.986 – 1.01 0.996 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 0.996 0.968 – 1.02 0.754 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.02 0.968 – 1.07 0.483 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 0.999 0.983 – 1.02 0.941 15186 151648 all phecode
565 Anal and rectal conditions Digestive 0.999 0.982 – 1.02 0.892 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 0.999 0.975 – 1.02 0.911 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.04 0.972 – 1.11 0.259 929 9293 all phecode
568 Other disorders of peritoneum Digestive 1.02 0.981 – 1.05 0.364 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.01 0.974 – 1.05 0.585 3101 30987 all phecode
569 Other disorders of intestine Digestive 0.995 0.964 – 1.03 0.75 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.96 0.81 – 1.14 0.64 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 0.971 0.885 – 1.06 0.526 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.01 0.972 – 1.05 0.627 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.02 0.971 – 1.07 0.418 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.989 0.815 – 1.2 0.913 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 0.961 0.844 – 1.09 0.548 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.01 0.941 – 1.07 0.867 976 9804 all phecode
571.81 Portal hypertension Digestive 1.03 0.939 – 1.12 0.553 528 5285 all phecode
572 Ascites (non malignant) Digestive 1.05 0.996 – 1.11 0.0679 1544 15454 all phecode
573 Other disorders of liver Digestive 1.02 0.971 – 1.08 0.377 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 1.06 0.855 – 1.32 0.591 96 960 all phecode
573.3 Hepatomegaly Digestive 0.961 0.855 – 1.08 0.505 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 0.999 0.932 – 1.07 0.985 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 0.997 0.963 – 1.03 0.861 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 0.883 0.768 – 1.01 0.0795 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 0.996 0.98 – 1.01 0.662 15607 156123 all phecode
574.1 Cholelithiasis Digestive 0.99 0.973 – 1.01 0.279 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.984 0.934 – 1.04 0.558 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1 0.973 – 1.03 0.958 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 1.01 0.974 – 1.05 0.518 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.01 0.968 – 1.05 0.721 2748 27523 all phecode
575 Other biliary tract disease Digestive 1.01 0.974 – 1.04 0.675 3867 38724 all phecode
575.1 Cholangitis Digestive 1.03 0.936 – 1.13 0.558 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 1.05 0.972 – 1.13 0.225 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 1 0.908 – 1.1 0.99 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 1 0.948 – 1.06 0.953 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 1.02 0.961 – 1.09 0.465 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.928 0.834 – 1.03 0.166 348 3488 all phecode
577 Diseases of pancreas Digestive 0.99 0.952 – 1.03 0.62 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 0.987 0.943 – 1.03 0.564 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 0.932 0.854 – 1.02 0.115 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.01 0.908 – 1.12 0.872 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.992 – 1.02 0.369 20626 206278 all phecode
578.1 Hematemesis Digestive 1.01 0.964 – 1.06 0.668 1958 19564 all phecode
578.2 Blood in stool Digestive 1 0.964 – 1.05 0.856 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.01 0.989 – 1.03 0.432 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1 0.974 – 1.03 0.902 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.01 0.96 – 1.07 0.652 1548 15498 all phecode
579.2 Splenomegaly Digestive 1.07 0.969 – 1.19 0.176 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.98 0.932 – 1.03 0.443 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.03 0.973 – 1.08 0.339 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 1.01 0.946 – 1.08 0.792 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.818 0.651 – 1.03 0.0858 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.05 0.878 – 1.26 0.585 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.02 0.955 – 1.1 0.498 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.04 0.944 – 1.14 0.449 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.952 0.835 – 1.08 0.458 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.964 0.847 – 1.1 0.582 253 2529 all phecode
585 Renal failure Genitourinary 1 0.981 – 1.03 0.696 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 1.01 0.983 – 1.05 0.378 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 0.994 0.942 – 1.05 0.817 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.992 0.954 – 1.03 0.704 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 1.01 0.922 – 1.11 0.825 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.02 0.983 – 1.05 0.318 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.961 0.834 – 1.11 0.578 208 2089 all phecode
586.11 Small kidney Genitourinary 0.978 0.839 – 1.14 0.779 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 0.995 0.939 – 1.05 0.871 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.09 0.874 – 1.37 0.438 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.02 0.956 – 1.1 0.498 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 0.983 0.885 – 1.09 0.74 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 0.974 0.794 – 1.2 0.803 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.03 0.855 – 1.24 0.746 116 1158 all phecode
590 Pyelonephritis Genitourinary 1.03 0.975 – 1.09 0.286 1328 13285 all phecode
591 Urinary tract infection Genitourinary 1 0.981 – 1.02 0.97 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 0.997 0.96 – 1.04 0.882 2966 29661 all phecode
592.1 Cystitis Genitourinary 1 0.966 – 1.04 0.876 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 0.934 0.789 – 1.11 0.431 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 0.92 0.86 – 0.984 0.0156 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.933 0.819 – 1.06 0.304 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.973 0.833 – 1.14 0.727 165 1662 all phecode
593 Hematuria Genitourinary 1 0.985 – 1.02 0.851 16068 160204 all phecode
594 Urinary calculus Genitourinary 0.987 0.962 – 1.01 0.323 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 0.98 0.945 – 1.02 0.265 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.07 0.996 – 1.16 0.064 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 0.963 0.924 – 1 0.0739 2401 24024 all phecode
594.8 Renal colic Genitourinary 0.948 0.907 – 0.992 0.02 2050 20500 all phecode
595 Hydronephrosis Genitourinary 1 0.959 – 1.05 0.855 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 1.02 0.995 – 1.04 0.13 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 1.04 0.99 – 1.09 0.122 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 1 0.95 – 1.05 0.988 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.02 0.987 – 1.05 0.245 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.01 0.977 – 1.05 0.491 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 0.941 0.745 – 1.19 0.61 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.02 0.984 – 1.06 0.284 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.986 0.878 – 1.11 0.813 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.999 0.984 – 1.01 0.905 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 1.25 1.05 – 1.47 0.00963 166 1670 all phecode
599.2 Retention of urine Genitourinary 1 0.978 – 1.03 0.845 6718 67168 all phecode
599.3 Dysuria Genitourinary 1.02 0.964 – 1.09 0.439 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 0.986 0.965 – 1.01 0.208 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.02 0.991 – 1.06 0.163 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 0.988 0.813 – 1.2 0.904 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 0.998 0.771 – 1.29 0.986 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 1.02 0.97 – 1.07 0.481 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 1.02 1 – 1.04 0.0447 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 1.02 0.973 – 1.07 0.428 2081 20818 all phecode
601.1 Prostatitis Genitourinary 1.03 0.981 – 1.09 0.214 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 0.93 0.817 – 1.06 0.274 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 1.03 0.966 – 1.11 0.338 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.03 0.79 – 1.34 0.83 59 588 all phecode
601.4 Balanoposthitis Genitourinary 0.912 0.809 – 1.03 0.128 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.07 0.947 – 1.2 0.295 303 3019 all phecode
602 Other disorders of prostate Genitourinary 1.01 0.954 – 1.07 0.75 1341 13408 all phecode
603 Other disorders of testis Genitourinary 1.01 0.962 – 1.05 0.798 2150 21512 all phecode
603.1 Hydrocele Genitourinary 0.963 0.91 – 1.02 0.183 1339 13402 all phecode
604 Disorders of penis Genitourinary 1 0.965 – 1.04 0.99 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.993 0.955 – 1.03 0.741 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.01 0.891 – 1.14 0.922 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 1 0.966 – 1.04 0.814 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.971 0.845 – 1.12 0.678 214 2138 all phecode
609.1 Infertility, male Genitourinary 0.99 0.776 – 1.26 0.932 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.901 0.77 – 1.05 0.19 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 1.01 0.967 – 1.05 0.709 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 0.986 0.922 – 1.05 0.672 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 0.991 0.881 – 1.11 0.882 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 1.04 0.922 – 1.17 0.532 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 1.01 0.958 – 1.07 0.675 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.969 0.897 – 1.05 0.421 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.07 1.01 – 1.12 0.0135 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 0.952 0.72 – 1.26 0.732 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 1.08 1.03 – 1.14 0.00407 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.998 0.932 – 1.07 0.962 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1 0.934 – 1.08 0.944 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 0.981 0.779 – 1.24 0.87 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 1.02 0.967 – 1.07 0.514 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.07 0.992 – 1.16 0.0793 720 7210 all phecode
613.5 Mastodynia Genitourinary 0.873 0.69 – 1.1 0.259 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.976 0.903 – 1.05 0.533 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 0.982 0.876 – 1.1 0.76 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 0.997 0.867 – 1.15 0.967 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.04 1.01 – 1.07 0.00474 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.02 0.98 – 1.06 0.331 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.03 0.959 – 1.11 0.42 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.983 0.753 – 1.28 0.899 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.06 0.959 – 1.17 0.261 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.01 0.906 – 1.13 0.832 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.04 0.919 – 1.17 0.544 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.05 1.01 – 1.09 0.026 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.08 1.02 – 1.15 0.00719 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.03 0.93 – 1.14 0.573 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.03 0.955 – 1.11 0.447 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.05 0.932 – 1.19 0.407 274 2737 all phecode
615 Endometriosis Genitourinary 1.04 1.01 – 1.08 0.0115 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.08 0.962 – 1.22 0.189 304 3037 all phecode
618 Genital prolapse Genitourinary 0.994 0.975 – 1.01 0.508 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1 0.979 – 1.03 0.841 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.978 0.951 – 1.01 0.118 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.942 0.862 – 1.03 0.191 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.04 0.963 – 1.13 0.307 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.996 0.974 – 1.02 0.719 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1 0.931 – 1.08 0.907 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1.01 0.973 – 1.04 0.664 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.997 0.96 – 1.04 0.898 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.999 0.952 – 1.05 0.983 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.984 0.93 – 1.04 0.572 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 1.03 0.816 – 1.3 0.796 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 1.02 0.959 – 1.09 0.52 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 1.03 1.01 – 1.06 0.000868 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 1.03 1.01 – 1.06 0.00438 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 1.05 1.01 – 1.08 0.0117 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.02 0.964 – 1.08 0.478 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 1.03 0.956 – 1.11 0.455 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.985 0.862 – 1.13 0.826 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 1.04 0.94 – 1.15 0.461 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 0.979 0.953 – 1.01 0.126 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.04 1 – 1.08 0.0279 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 1.06 1 – 1.13 0.0506 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.03 1.01 – 1.04 0.00139 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.03 1.01 – 1.05 0.000491 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.875 0.719 – 1.06 0.179 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.05 1.02 – 1.07 3.71e-05 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 1.01 0.969 – 1.06 0.544 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 1.06 1.02 – 1.1 0.00072 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 1.04 0.993 – 1.1 0.0928 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.923 0.79 – 1.08 0.311 159 1587 all phecode
626.8 Infertility, female Genitourinary 1.04 0.98 – 1.1 0.214 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1 0.984 – 1.02 0.687 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 1 0.981 – 1.02 0.853 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 1 0.86 – 1.17 0.972 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.04 0.974 – 1.1 0.262 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 1.07 0.947 – 1.2 0.286 310 3097 all phecode
628 Ovarian cyst Genitourinary 1.07 1.04 – 1.1 1.42e-05 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.01 0.981 – 1.04 0.514 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.982 0.925 – 1.04 0.561 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.01 0.904 – 1.13 0.881 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.02 0.974 – 1.07 0.402 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.04 0.971 – 1.12 0.251 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.02 0.965 – 1.08 0.447 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.02 0.981 – 1.07 0.286 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 1.03 0.946 – 1.12 0.524 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.07 1 – 1.14 0.0379 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 0.816 0.645 – 1.03 0.088 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.964 0.907 – 1.02 0.233 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.892 0.796 – 0.999 0.0481 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.912 0.797 – 1.04 0.182 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.868 0.739 – 1.02 0.0856 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.01 0.954 – 1.07 0.703 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.03 0.983 – 1.07 0.232 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.02 0.792 – 1.32 0.86 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.939 0.831 – 1.06 0.315 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.938 0.773 – 1.14 0.519 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.01 0.868 – 1.17 0.923 193 1922 all phecode
650 Normal delivery Pregnancy Complications 0.986 0.941 – 1.03 0.552 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 0.936 0.841 – 1.04 0.228 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1.01 0.962 – 1.06 0.647 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.983 0.93 – 1.04 0.541 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.18 0.918 – 1.52 0.197 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.03 0.998 – 1.06 0.0656 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.882 0.725 – 1.07 0.209 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 1.01 0.964 – 1.05 0.739 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.964 0.882 – 1.05 0.413 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 1.02 0.99 – 1.05 0.197 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.03 0.987 – 1.07 0.187 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.05 0.901 – 1.23 0.51 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.08 0.948 – 1.23 0.248 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.828 0.648 – 1.06 0.133 63 624 all phecode
679 Complications of in utero procedures Dermatologic 0.981 0.74 – 1.3 0.895 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 0.993 0.969 – 1.02 0.561 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.01 0.927 – 1.1 0.814 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.01 0.923 – 1.1 0.848 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.993 0.966 – 1.02 0.635 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.995 0.968 – 1.02 0.742 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.993 0.966 – 1.02 0.622 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.01 0.933 – 1.1 0.737 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.01 0.954 – 1.07 0.747 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 0.974 0.933 – 1.02 0.229 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 1.04 0.95 – 1.13 0.43 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 1.04 0.928 – 1.16 0.532 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1.06 0.969 – 1.16 0.203 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.02 0.973 – 1.06 0.465 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.11 0.985 – 1.26 0.0866 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 0.926 0.763 – 1.12 0.433 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 0.989 0.952 – 1.03 0.565 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.01 0.978 – 1.03 0.708 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 1.12 0.878 – 1.43 0.362 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 1.07 0.808 – 1.41 0.652 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 0.888 0.74 – 1.06 0.199 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.982 0.92 – 1.05 0.581 986 9854 all phecode
694.1 Vitiligo Dermatologic 1.03 0.783 – 1.36 0.827 60 599 all phecode
694.2 Other dyschromia Dermatologic 0.97 0.902 – 1.04 0.407 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 0.955 0.794 – 1.15 0.621 117 1170 all phecode
695 Erythematous conditions Dermatologic 1.03 0.984 – 1.07 0.225 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 0.944 0.776 – 1.15 0.561 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 0.953 0.806 – 1.13 0.577 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 0.929 0.726 – 1.19 0.56 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.02 0.808 – 1.29 0.866 73 727 all phecode
695.3 Rosacea Dermatologic 1.1 0.978 – 1.25 0.109 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.03 0.93 – 1.14 0.567 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.933 0.779 – 1.12 0.456 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.02 0.912 – 1.14 0.724 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 1.04 0.964 – 1.12 0.323 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 0.922 0.809 – 1.05 0.22 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 0.818 0.648 – 1.03 0.0921 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.03 0.939 – 1.14 0.493 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 0.995 0.953 – 1.04 0.804 2252 22509 all phecode
696.4 Psoriasis Dermatologic 0.99 0.947 – 1.03 0.637 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 0.988 0.94 – 1.04 0.643 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.01 0.934 – 1.09 0.825 706 7052 all phecode
697 Sarcoidosis Dermatologic 1.03 0.939 – 1.12 0.572 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 0.975 0.905 – 1.05 0.5 782 7814 all phecode
700 Corns and callosities Dermatologic 1.03 0.912 – 1.16 0.657 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.01 0.976 – 1.04 0.703 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 1.08 0.861 – 1.35 0.511 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1 0.962 – 1.05 0.847 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.05 0.813 – 1.35 0.719 61 610 all phecode
701.4 Keloid scar Dermatologic 0.975 0.846 – 1.12 0.727 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.03 0.935 – 1.14 0.534 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.26 1.02 – 1.56 0.0318 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.975 0.948 – 1 0.0719 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 1 0.964 – 1.05 0.862 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 0.943 0.91 – 0.979 0.00178 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 1.01 0.903 – 1.12 0.91 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 0.994 0.931 – 1.06 0.848 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 0.978 0.951 – 1.01 0.119 5267 52727 all phecode
704.1 Alopecia Dermatologic 0.981 0.821 – 1.17 0.83 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.813 0.644 – 1.03 0.0817 76 759 all phecode
705 Disorders of sweat glands Dermatologic 0.884 0.771 – 1.01 0.0758 228 2287 all phecode
705.3 Hidradenitis Dermatologic 0.915 0.787 – 1.06 0.245 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 0.954 0.877 – 1.04 0.277 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 0.989 0.967 – 1.01 0.342 8317 83195 all phecode
706.1 Acne Dermatologic 0.832 0.662 – 1.05 0.115 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 0.992 0.97 – 1.01 0.466 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 0.99 0.945 – 1.04 0.664 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 0.981 0.917 – 1.05 0.586 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.971 0.938 – 1 0.093 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 1.03 0.941 – 1.13 0.511 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 1.11 0.943 – 1.3 0.212 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.07 0.833 – 1.38 0.583 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.955 0.919 – 0.993 0.0208 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.962 0.885 – 1.05 0.361 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 0.973 0.892 – 1.06 0.532 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.986 0.853 – 1.14 0.853 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.966 0.872 – 1.07 0.513 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.01 0.917 – 1.12 0.788 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 0.964 0.862 – 1.08 0.516 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 0.81 0.641 – 1.02 0.0771 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.961 0.819 – 1.13 0.622 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 0.971 0.761 – 1.24 0.809 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1 0.971 – 1.03 0.991 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.01 0.979 – 1.04 0.538 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1 0.951 – 1.05 0.991 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.967 0.796 – 1.18 0.74 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.02 0.937 – 1.1 0.687 618 6177 all phecode
716 Other arthropathies Musculoskeletal 1 0.991 – 1.01 0.723 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1 0.967 – 1.04 0.956 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.01 0.993 – 1.03 0.25 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 1 0.992 – 1.01 0.649 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.02 0.962 – 1.08 0.492 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 0.967 0.936 – 1 0.0529 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 0.988 0.965 – 1.01 0.298 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.988 0.96 – 1.02 0.397 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.05 0.905 – 1.21 0.531 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 0.856 0.768 – 0.953 0.00446 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 0.992 0.971 – 1.01 0.481 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.984 0.898 – 1.08 0.729 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.01 0.975 – 1.05 0.487 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 0.978 0.781 – 1.22 0.845 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.996 0.966 – 1.03 0.793 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 0.994 0.908 – 1.09 0.888 517 5173 all phecode
723.1 Torticollis Musculoskeletal 0.891 0.741 – 1.07 0.216 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1 0.956 – 1.05 0.99 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 0.985 0.89 – 1.09 0.762 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 0.974 0.882 – 1.08 0.611 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.05 0.81 – 1.35 0.724 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.01 0.958 – 1.06 0.761 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1 0.984 – 1.02 0.936 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 0.999 0.978 – 1.02 0.902 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 1.03 0.922 – 1.15 0.595 334 3336 all phecode
726.3 Bursitis Musculoskeletal 1.02 0.951 – 1.1 0.558 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1 0.979 – 1.03 0.848 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1 0.965 – 1.04 0.861 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 0.927 0.767 – 1.12 0.433 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.02 0.984 – 1.06 0.266 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 0.984 0.904 – 1.07 0.719 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.974 0.873 – 1.09 0.639 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.01 0.85 – 1.19 0.942 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.984 0.951 – 1.02 0.334 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.04 0.942 – 1.16 0.409 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 0.99 0.958 – 1.02 0.545 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.984 0.951 – 1.02 0.375 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.01 0.987 – 1.04 0.319 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.991 0.929 – 1.06 0.794 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 1.09 0.883 – 1.34 0.433 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.956 0.844 – 1.08 0.477 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.95 0.836 – 1.08 0.432 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 0.947 0.863 – 1.04 0.257 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.966 0.84 – 1.11 0.622 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.936 0.725 – 1.21 0.61 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.971 0.925 – 1.02 0.238 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 0.925 0.826 – 1.04 0.181 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.01 0.925 – 1.11 0.805 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 0.948 0.795 – 1.13 0.554 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.977 0.923 – 1.03 0.431 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 0.963 0.794 – 1.17 0.703 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 1.01 0.99 – 1.03 0.309 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 0.956 0.829 – 1.1 0.54 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 1.02 0.996 – 1.06 0.0963 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.03 0.983 – 1.08 0.216 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 1.02 0.967 – 1.07 0.484 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.01 0.981 – 1.03 0.659 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.98 0.932 – 1.03 0.448 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.01 0.885 – 1.16 0.871 248 2476 all phecode
737 Curvature of spine Musculoskeletal 0.956 0.9 – 1.02 0.149 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.951 0.894 – 1.01 0.117 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.02 0.973 – 1.07 0.413 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.01 0.961 – 1.07 0.623 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 0.942 0.86 – 1.03 0.193 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 0.992 0.98 – 1 0.226 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.99 0.974 – 1.01 0.191 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.985 0.964 – 1.01 0.171 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.998 0.893 – 1.11 0.966 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.04 0.957 – 1.13 0.355 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.997 0.979 – 1.02 0.737 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.03 0.992 – 1.06 0.138 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 1.05 0.858 – 1.29 0.619 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 0.99 0.912 – 1.08 0.818 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 0.98 0.83 – 1.16 0.816 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 1.05 0.992 – 1.11 0.093 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 0.999 0.827 – 1.21 0.995 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 1.23 0.925 – 1.63 0.155 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.957 0.921 – 0.994 0.0236 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 0.906 0.813 – 1.01 0.073 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.03 0.837 – 1.26 0.808 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 0.913 0.834 – 0.999 0.0466 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 0.976 0.932 – 1.02 0.309 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1 0.979 – 1.03 0.869 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 1 0.978 – 1.03 0.779 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.999 0.971 – 1.03 0.915 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 0.995 0.911 – 1.09 0.903 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 0.942 0.862 – 1.03 0.189 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.02 0.949 – 1.1 0.588 815 8144 all phecode
745 Pain in joint Musculoskeletal 1.02 0.996 – 1.04 0.104 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.02 0.978 – 1.06 0.413 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.01 0.971 – 1.05 0.607 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.994 0.913 – 1.08 0.898 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.02 0.894 – 1.17 0.753 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1 0.956 – 1.05 0.903 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.06 0.906 – 1.25 0.451 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.05 0.79 – 1.4 0.733 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.883 0.787 – 0.99 0.0338 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 1.04 0.962 – 1.13 0.317 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.04 0.925 – 1.16 0.535 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1 0.863 – 1.16 0.993 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.06 0.953 – 1.19 0.272 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.01 0.876 – 1.16 0.93 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.21 0.998 – 1.47 0.052 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.978 0.929 – 1.03 0.411 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.985 0.912 – 1.06 0.705 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.992 0.903 – 1.09 0.871 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.02 0.885 – 1.17 0.805 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.99 0.922 – 1.06 0.787 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 1.03 0.934 – 1.14 0.542 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.94 0.842 – 1.05 0.277 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.99 0.881 – 1.11 0.86 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 0.998 0.877 – 1.14 0.976 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 1.04 0.899 – 1.2 0.612 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.948 0.756 – 1.19 0.643 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.92 0.769 – 1.1 0.365 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1 0.799 – 1.26 0.983 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.988 0.814 – 1.2 0.904 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.997 0.901 – 1.1 0.959 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.972 0.839 – 1.13 0.706 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.919 0.78 – 1.08 0.317 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.935 0.765 – 1.14 0.515 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.999 0.917 – 1.09 0.972 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.19 0.94 – 1.51 0.147 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.947 0.859 – 1.04 0.277 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.12 0.95 – 1.33 0.173 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.21 0.937 – 1.57 0.143 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.07 0.931 – 1.24 0.331 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.15 0.924 – 1.42 0.215 96 959 all phecode
760 Back pain Symptoms 1.01 0.989 – 1.03 0.396 11126 111353 all phecode
761 Cervicalgia Symptoms 1.01 0.961 – 1.06 0.725 1791 17901 all phecode
764 Sciatica Symptoms 1.01 0.965 – 1.05 0.774 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.971 0.915 – 1.03 0.339 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 0.985 0.909 – 1.07 0.711 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.03 0.957 – 1.1 0.471 870 8687 all phecode
771.1 Swelling of limb Symptoms 1.02 0.988 – 1.05 0.24 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 1.1 1.01 – 1.19 0.0265 659 6581 all phecode
773 Pain in limb Symptoms 0.999 0.974 – 1.03 0.969 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 0.891 0.76 – 1.04 0.153 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.997 0.951 – 1.05 0.908 1870 18715 all phecode
782.3 Edema Symptoms 1.01 0.963 – 1.07 0.599 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 1.03 0.89 – 1.2 0.672 175 1748 all phecode
783 Fever of unknown origin Symptoms 1.03 0.997 – 1.07 0.0712 3911 39105 all phecode
785 Abdominal pain Symptoms 1 0.994 – 1.01 0.408 40080 301686 all phecode
788 Syncope and collapse Symptoms 1.01 0.99 – 1.03 0.284 9069 90813 all phecode
789 Nausea and vomiting Symptoms 1 0.986 – 1.02 0.635 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.01 0.859 – 1.2 0.865 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 1.1 0.884 – 1.37 0.392 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.02 0.994 – 1.05 0.135 6357 63635 all phecode
791 Gangrene Symptoms 1.01 0.928 – 1.11 0.771 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1.09 0.875 – 1.35 0.458 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.965 0.81 – 1.15 0.689 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 0.971 0.89 – 1.06 0.504 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.97 0.8 – 1.18 0.754 120 1198 all phecode
797 Shock Symptoms 0.915 0.781 – 1.07 0.274 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 0.832 0.683 – 1.01 0.0659 102 1020 all phecode
798 Malaise and fatigue Symptoms 1.01 0.978 – 1.05 0.473 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 0.943 0.868 – 1.03 0.173 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 0.992 0.968 – 1.02 0.504 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.974 0.929 – 1.02 0.291 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.882 0.755 – 1.03 0.111 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1 0.961 – 1.05 0.85 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 0.952 0.885 – 1.02 0.192 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.02 0.972 – 1.06 0.492 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.01 0.96 – 1.06 0.774 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.964 0.894 – 1.04 0.336 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.998 0.976 – 1.02 0.852 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 0.994 0.945 – 1.04 0.8 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.997 0.969 – 1.03 0.82 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.01 0.955 – 1.06 0.793 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.992 0.958 – 1.03 0.676 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.01 0.957 – 1.07 0.677 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 1.01 0.938 – 1.09 0.802 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.03 0.974 – 1.09 0.285 1300 12998 all phecode
817 Concussion Injuries & Poisonings 1.02 0.897 – 1.16 0.76 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.01 0.923 – 1.1 0.837 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.05 1.01 – 1.09 0.0119 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 0.991 0.942 – 1.04 0.708 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 0.984 0.94 – 1.03 0.469 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 0.999 0.983 – 1.02 0.931 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1 0.917 – 1.09 0.977 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 1 0.912 – 1.1 0.964 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.02 0.99 – 1.05 0.195 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.06 0.899 – 1.26 0.47 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.03 0.936 – 1.13 0.568 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.02 0.972 – 1.07 0.434 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.02 0.96 – 1.08 0.577 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.983 0.948 – 1.02 0.362 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 0.998 0.962 – 1.03 0.892 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1.4 1.08 – 1.81 0.0102 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.04 1 – 1.07 0.0424 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.924 0.816 – 1.05 0.209 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 1.08 0.928 – 1.25 0.334 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.02 0.985 – 1.06 0.237 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.12 0.975 – 1.29 0.108 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 0.925 0.725 – 1.18 0.533 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 0.997 0.965 – 1.03 0.843 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.987 0.742 – 1.31 0.928 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.03 0.84 – 1.27 0.747 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.957 0.823 – 1.11 0.572 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 0.98 0.892 – 1.08 0.681 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 1.06 0.933 – 1.22 0.351 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.12 0.957 – 1.32 0.155 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 0.921 0.786 – 1.08 0.307 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 0.951 0.9 – 1.01 0.0795 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1 0.974 – 1.04 0.762 4260 42663 all phecode
916 Contusion Injuries & Poisonings 1.03 0.977 – 1.09 0.265 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.987 0.846 – 1.15 0.869 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.972 0.876 – 1.08 0.6 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.966 0.848 – 1.1 0.596 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1 0.96 – 1.05 0.854 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.17 1.01 – 1.35 0.0313 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.889 0.732 – 1.08 0.236 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.07 0.981 – 1.17 0.125 550 5509 all phecode
947 Urticaria Injuries & Poisonings 0.984 0.883 – 1.1 0.764 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 1.13 1.02 – 1.26 0.0204 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.08 0.974 – 1.19 0.149 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.897 0.792 – 1.01 0.084 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.973 0.888 – 1.07 0.55 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.04 0.793 – 1.35 0.794 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.85 0.678 – 1.07 0.159 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.01 0.996 – 1.03 0.142 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.01 0.998 – 1.03 0.0851 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.04 0.938 – 1.14 0.492 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.01 0.939 – 1.08 0.834 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.08 0.974 – 1.2 0.142 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.09 0.98 – 1.21 0.111 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1 0.874 – 1.15 0.98 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.06 0.934 – 1.19 0.385 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.05 0.923 – 1.18 0.484 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1 0.977 – 1.03 0.813 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.02 0.958 – 1.08 0.56 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.03 0.939 – 1.13 0.509 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.917 0.83 – 1.01 0.0844 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.01 0.926 – 1.11 0.79 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.978 0.899 – 1.06 0.599 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.05 1 – 1.1 0.0473 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.996 0.86 – 1.15 0.961 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.1 0.972 – 1.25 0.128 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.992 0.799 – 1.23 0.941 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.08 0.88 – 1.31 0.476 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.21 0.981 – 1.49 0.0745 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.1 0.849 – 1.43 0.467 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.815 0.634 – 1.05 0.113 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.18 1.03 – 1.36 0.0151 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.11 1.03 – 1.2 0.00823 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.987 0.853 – 1.14 0.858 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.04 0.792 – 1.36 0.784 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.02 0.836 – 1.24 0.853 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 1.07 0.884 – 1.3 0.477 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.05 0.838 – 1.31 0.681 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 0.984 0.948 – 1.02 0.381 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.01 0.973 – 1.05 0.602 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 1.01 0.973 – 1.05 0.602 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 1 0.982 – 1.03 0.704 8743 88089 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 0.994 0.955 – 1.03 0.765 2687 27082 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.03 0.946 – 1.11 0.531 639 6511 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.02 0.947 – 1.09 0.65 857 8585 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.71 1.24 – 2.35 0.00107 55 549 exclusion phecode
010 Tuberculosis Infectious Diseases 0.893 0.764 – 1.04 0.151 166 1654 exclusion phecode
038 Septicemia Infectious Diseases 1.03 0.996 – 1.06 0.0833 4093 41660 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.08 1.01 – 1.16 0.0329 839 8480 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.01 0.922 – 1.11 0.81 490 4968 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 0.999 0.98 – 1.02 0.896 11871 120031 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 0.99 0.955 – 1.03 0.605 3094 31292 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 0.989 0.939 – 1.04 0.659 1623 16398 exclusion phecode
041.4 E. coli Infectious Diseases 1.01 0.97 – 1.05 0.659 2663 27221 exclusion phecode
053 Herpes zoster Infectious Diseases 1.08 0.977 – 1.2 0.126 409 4116 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.19 0.955 – 1.48 0.123 95 944 exclusion phecode
054 Herpes simplex Infectious Diseases 1.09 0.954 – 1.25 0.2 211 2098 exclusion phecode
070 Viral hepatitis Infectious Diseases 0.974 0.896 – 1.06 0.542 585 5903 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 0.962 0.744 – 1.25 0.77 68 686 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.992 0.833 – 1.18 0.928 132 1329 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 0.964 0.852 – 1.09 0.568 255 2564 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.07 0.942 – 1.22 0.296 274 2760 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 0.913 0.827 – 1.01 0.0746 425 4274 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.829 0.704 – 0.977 0.0247 147 1467 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.809 0.676 – 0.968 0.0207 117 1168 exclusion phecode
078 Viral warts & HPV Infectious Diseases 1.01 0.944 – 1.07 0.828 986 9999 exclusion phecode
079 Viral infection Infectious Diseases 1.01 0.966 – 1.05 0.797 2735 27598 exclusion phecode
079.1 Varicella infection Infectious Diseases 1.06 0.828 – 1.37 0.629 64 637 exclusion phecode
080 Postoperative infection Infectious Diseases 1.01 0.984 – 1.05 0.358 4395 44638 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.03 0.988 – 1.07 0.164 2437 24697 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.03 0.808 – 1.32 0.793 71 706 exclusion phecode
1000 Burns Injuries & Poisonings 1.05 0.963 – 1.15 0.262 576 5786 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 0.986 0.93 – 1.05 0.651 1195 11969 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.01 0.984 – 1.04 0.393 5446 54604 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 0.971 0.862 – 1.09 0.635 295 2982 exclusion phecode
1005 Other symptoms Injuries & Poisonings 0.966 0.915 – 1.02 0.218 1422 14383 exclusion phecode
1006 Crushing injury Injuries & Poisonings 0.947 0.831 – 1.08 0.413 256 2556 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 0.984 0.863 – 1.12 0.81 256 2550 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.01 0.944 – 1.07 0.837 1006 10122 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 1.01 0.988 – 1.03 0.379 8454 84699 exclusion phecode
1010 Other tests Injuries & Poisonings 0.986 0.96 – 1.01 0.307 5891 59290 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.977 0.956 – 0.998 0.0314 9072 91278 exclusion phecode
1012 Late effect Injuries & Poisonings 0.998 0.819 – 1.22 0.983 105 1053 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.01 0.905 – 1.14 0.807 313 3162 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.94 0.738 – 1.2 0.617 66 658 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 1.01 0.977 – 1.04 0.581 4155 42145 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.01 0.993 – 1.03 0.274 15777 158468 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.07 0.938 – 1.21 0.327 277 2804 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 1.05 0.92 – 1.19 0.487 271 2745 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.957 0.749 – 1.22 0.722 74 754 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.07 0.893 – 1.27 0.482 140 1408 exclusion phecode
112 Candidiasis Infectious Diseases 0.999 0.955 – 1.05 0.976 2080 21202 exclusion phecode
117 Mycoses Infectious Diseases 1.03 0.911 – 1.17 0.615 270 2713 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1 0.854 – 1.17 0.992 164 1648 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.88 0.703 – 1.1 0.264 80 798 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 0.85 0.675 – 1.07 0.17 69 689 exclusion phecode
134 Helminthiases Infectious Diseases 1.01 0.84 – 1.22 0.9 127 1264 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.02 0.83 – 1.25 0.86 106 1057 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1 0.87 – 1.16 0.948 202 2045 exclusion phecode
145 Cancer of mouth Neoplasms 0.971 0.895 – 1.05 0.485 640 6405 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.04 0.923 – 1.17 0.534 310 3094 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 1.09 0.883 – 1.34 0.434 105 1047 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 0.963 0.743 – 1.25 0.779 54 538 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.984 0.907 – 1.07 0.697 633 6337 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 0.953 0.838 – 1.08 0.466 252 2515 exclusion phecode
149.4 Cancer of larynx Neoplasms 0.993 0.873 – 1.13 0.919 264 2640 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.04 0.789 – 1.36 0.803 57 570 exclusion phecode
150 Cancer of esophagus Neoplasms 1.04 0.966 – 1.12 0.292 760 7614 exclusion phecode
151 Cancer of stomach Neoplasms 1.02 0.936 – 1.11 0.661 566 5686 exclusion phecode
153 Colorectal cancer Neoplasms 0.995 0.965 – 1.03 0.742 4524 45670 exclusion phecode
153.2 Colon cancer Neoplasms 0.988 0.952 – 1.03 0.52 3069 30960 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1 0.956 – 1.05 0.989 2136 21579 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.872 0.788 – 0.966 0.0086 395 4002 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.826 0.698 – 0.977 0.0254 157 1578 exclusion phecode
157 Pancreatic cancer Neoplasms 1 0.928 – 1.09 0.905 657 6563 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.02 0.961 – 1.09 0.462 1050 10608 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1 0.973 – 1.03 0.996 5420 55555 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.981 0.843 – 1.14 0.808 188 1894 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.92 0.804 – 1.05 0.231 203 2045 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.03 0.848 – 1.26 0.748 99 1920 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.877 0.673 – 1.14 0.331 60 599 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.04 1 – 1.08 0.034 2802 28148 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.04 0.995 – 1.09 0.0802 2210 22234 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 1.06 0.961 – 1.17 0.239 428 4353 exclusion phecode
170.1 Bone cancer Neoplasms 1.1 0.918 – 1.32 0.303 130 1307 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1.05 0.939 – 1.18 0.378 323 3293 exclusion phecode
172 Skin cancer Neoplasms 1.02 1 – 1.04 0.0259 13421 134485 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.07 1.02 – 1.11 0.00175 2669 26690 exclusion phecode
172.11 Melanomas of skin Neoplasms 1.07 1.03 – 1.11 0.00123 2701 27007 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1.02 0.996 – 1.04 0.11 10942 109648 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.914 0.844 – 0.991 0.0295 657 6634 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.12 0.962 – 1.3 0.146 181 1814 exclusion phecode
174 Breast cancer Neoplasms 1.03 1.01 – 1.04 0.00743 12565 126597 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1.03 1.01 – 1.05 0.00666 12355 124506 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.02 1 – 1.04 0.0226 11637 117502 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.09 0.904 – 1.32 0.355 114 1148 exclusion phecode
175 Acquired absence of breast Neoplasms 1.06 1.02 – 1.11 0.00697 2361 24010 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.02 0.978 – 1.07 0.327 2107 21747 exclusion phecode
180.1 Cervical cancer Neoplasms 0.993 0.87 – 1.13 0.918 249 2720 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.03 0.982 – 1.08 0.237 2032 20784 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 1.09 1.03 – 1.16 0.00487 1203 12836 exclusion phecode
185 Cancer of prostate Neoplasms 0.983 0.958 – 1.01 0.217 5974 58812 exclusion phecode
187 Cancer of other male genital organs Neoplasms 0.902 0.82 – 0.991 0.0316 449 4485 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.83 0.659 – 1.04 0.112 70 700 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.912 0.812 – 1.03 0.124 287 2868 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.04 0.849 – 1.26 0.732 110 1098 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.02 0.992 – 1.06 0.138 4139 41511 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.02 0.959 – 1.09 0.515 1069 10695 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.01 0.947 – 1.08 0.764 1029 10296 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.12 0.877 – 1.42 0.373 66 660 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.01 0.972 – 1.06 0.536 2398 24060 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.02 0.974 – 1.06 0.422 2132 21399 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.08 0.905 – 1.28 0.403 143 1436 exclusion phecode
190 Cancer of eye Neoplasms 1.09 0.936 – 1.27 0.265 175 1748 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.15 1.06 – 1.25 0.000461 689 6861 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 1.16 1.07 – 1.27 0.000716 566 5634 exclusion phecode
191.11 Cancer of brain Neoplasms 1.18 1.08 – 1.29 0.000371 525 5225 exclusion phecode
193 Thyroid cancer Neoplasms 1.07 0.955 – 1.2 0.241 345 3451 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.21 0.966 – 1.52 0.0968 94 946 exclusion phecode
195 Cancer, suspected or other Neoplasms 0.999 0.983 – 1.02 0.931 16370 165276 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1 0.985 – 1.02 0.892 15670 159314 exclusion phecode
197 Chemotherapy Neoplasms 1 0.991 – 1.02 0.515 20753 212909 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1 0.979 – 1.02 0.945 9005 95385 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.993 0.965 – 1.02 0.605 5184 53596 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.01 0.968 – 1.06 0.599 2138 22644 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.95 0.894 – 1.01 0.0978 1123 15473 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.03 0.985 – 1.07 0.207 2528 26609 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.02 0.951 – 1.1 0.548 812 8466 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 0.988 0.945 – 1.03 0.61 2111 21577 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.07 0.918 – 1.25 0.378 180 1888 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 0.982 0.93 – 1.04 0.511 1420 14298 exclusion phecode
199.4 Neurofibromatosis Neoplasms 0.985 0.801 – 1.21 0.884 92 948 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.18 1.11 – 1.26 9.35e-07 986 9884 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.2 1.07 – 1.33 0.00107 387 3859 exclusion phecode
201 Hodgkin's disease Neoplasms 0.962 0.846 – 1.09 0.552 259 2592 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.02 0.979 – 1.07 0.313 2256 22649 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.04 0.987 – 1.09 0.156 1797 18022 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.07 0.96 – 1.19 0.222 363 3630 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.03 0.946 – 1.12 0.492 579 5810 exclusion phecode
204 Leukemia Neoplasms 1.04 0.984 – 1.09 0.179 1652 16579 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1 0.922 – 1.09 0.911 574 5767 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.14 0.867 – 1.51 0.343 56 559 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1 0.915 – 1.1 0.967 504 5069 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.1 0.997 – 1.21 0.0581 458 4602 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 1.12 1 – 1.26 0.0438 327 3280 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.932 0.789 – 1.1 0.413 142 1435 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.04 0.951 – 1.14 0.401 555 5543 exclusion phecode
208 Benign neoplasm of colon Neoplasms 0.996 0.982 – 1.01 0.622 19766 191332 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.984 0.922 – 1.05 0.635 976 9751 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.01 0.98 – 1.04 0.557 5213 52251 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.921 0.826 – 1.03 0.139 347 3455 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.929 0.83 – 1.04 0.203 316 3175 exclusion phecode
214 Lipoma Neoplasms 1.03 1.01 – 1.06 0.0117 6213 62165 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.05 1.02 – 1.08 0.00289 4572 45716 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.07 1 – 1.14 0.036 1103 11018 exclusion phecode
216 Benign neoplasm of skin Neoplasms 1.03 1 – 1.05 0.038 7631 76365 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.962 0.886 – 1.04 0.358 627 6286 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.971 0.892 – 1.06 0.496 589 5914 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 1.05 1.03 – 1.08 9.82e-07 9817 100200 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 1.06 1.03 – 1.08 2.4e-07 10042 102376 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.12 1 – 1.25 0.0484 342 3548 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 1.07 1.02 – 1.13 0.0123 1396 14483 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.03 0.894 – 1.19 0.674 208 2196 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.905 0.773 – 1.06 0.213 160 1600 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.03 0.884 – 1.21 0.676 171 1728 exclusion phecode
224 Benign neoplasm of eye Neoplasms 1 0.84 – 1.2 0.96 129 1294 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.877 0.69 – 1.11 0.282 67 676 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.1 1.03 – 1.19 0.00898 808 8120 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.11 1.02 – 1.19 0.0101 767 7726 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.06 0.812 – 1.38 0.679 59 584 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.06 0.933 – 1.21 0.365 262 2651 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.987 0.92 – 1.06 0.718 858 8597 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.929 0.801 – 1.08 0.33 184 1852 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1 0.899 – 1.11 0.996 371 3689 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.988 0.878 – 1.11 0.847 308 3104 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.08 1.02 – 1.13 0.00471 1588 15912 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.04 1 – 1.09 0.0521 2385 23851 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.01 0.928 – 1.1 0.796 595 5983 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.03 0.965 – 1.09 0.417 1100 11040 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.997 0.908 – 1.1 0.958 469 4687 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.04 0.965 – 1.13 0.286 671 6751 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1 0.955 – 1.05 0.916 1839 18439 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 1.03 0.936 – 1.14 0.521 452 4536 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 0.739 0.601 – 0.909 0.00417 89 904 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 1.02 0.855 – 1.21 0.839 138 1374 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.01 0.995 – 1.03 0.171 14439 144247 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.05 0.982 – 1.11 0.166 1091 11030 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.843 0.694 – 1.03 0.0874 101 1004 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.01 0.995 – 1.03 0.152 13776 138151 exclusion phecode
245 Thyroiditis Endocrine/metabolic 1.05 0.928 – 1.19 0.447 286 2860 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.13 0.984 – 1.31 0.0828 217 2164 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.13 0.975 – 1.3 0.105 209 2084 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.02 0.923 – 1.14 0.657 395 3953 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 0.996 0.981 – 1.01 0.585 19696 185490 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1 0.964 – 1.04 0.913 2743 27550 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.03 0.902 – 1.18 0.64 238 2380 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.2 0.949 – 1.53 0.126 76 770 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1 0.913 – 1.1 0.945 471 4735 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.16 0.985 – 1.36 0.0758 160 1604 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.991 0.976 – 1.01 0.274 17746 169732 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.945 0.771 – 1.16 0.587 103 1042 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.08 0.936 – 1.25 0.291 200 2014 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.01 0.947 – 1.08 0.743 983 9880 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.05 0.957 – 1.15 0.309 501 5058 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 0.946 0.874 – 1.02 0.175 678 6810 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.912 0.804 – 1.03 0.149 265 2651 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.981 0.886 – 1.09 0.719 414 4168 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.03 0.864 – 1.24 0.72 131 1307 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.03 0.928 – 1.15 0.557 348 3489 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.02 0.963 – 1.08 0.52 1325 13307 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.02 0.954 – 1.09 0.549 931 9355 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.991 0.924 – 1.06 0.795 867 8666 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1 0.928 – 1.08 0.997 777 7756 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.814 0.687 – 0.966 0.0183 140 1413 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.986 0.911 – 1.07 0.721 680 6787 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.986 0.85 – 1.14 0.852 186 1859 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.991 0.8 – 1.23 0.936 94 944 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.98 0.863 – 1.11 0.757 260 2609 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.04 0.841 – 1.28 0.726 92 916 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.01 0.862 – 1.19 0.883 158 1568 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.07 0.984 – 1.16 0.117 634 6353 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1 0.859 – 1.17 0.979 180 1791 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.02 0.833 – 1.25 0.857 103 1023 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.985 0.78 – 1.24 0.899 76 758 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.11 0.994 – 1.23 0.0653 359 3605 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.11 0.998 – 1.24 0.0535 358 3595 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 1 0.882 – 1.15 0.944 236 2387 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.997 0.866 – 1.15 0.969 205 2081 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 0.971 0.827 – 1.14 0.722 160 1619 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.964 0.817 – 1.14 0.668 152 1539 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.06 0.867 – 1.3 0.565 101 1016 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 1.11 0.938 – 1.31 0.228 149 1493 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.07 0.924 – 1.24 0.369 197 2010 exclusion phecode
260.1 Cachexia Endocrine/metabolic 0.914 0.69 – 1.21 0.53 51 510 exclusion phecode
260.6 Anorexia Endocrine/metabolic 0.981 0.914 – 1.05 0.603 822 8281 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.02 0.961 – 1.08 0.505 1183 11921 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.02 0.947 – 1.1 0.592 749 7510 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.995 0.901 – 1.1 0.928 437 4437 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.834 0.659 – 1.06 0.132 71 763 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.951 0.833 – 1.08 0.45 239 2399 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.06 0.951 – 1.19 0.279 337 3376 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.19 1.05 – 1.34 0.00532 302 3023 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.17 1.02 – 1.33 0.0225 260 2605 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.16 0.997 – 1.36 0.0539 191 1907 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 0.85 0.707 – 1.02 0.0823 112 1122 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.25 0.973 – 1.59 0.0812 68 688 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.03 0.871 – 1.21 0.756 156 1591 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.06 0.892 – 1.27 0.492 135 1386 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.994 0.982 – 1 0.261 34679 234658 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.993 0.982 – 1 0.256 34608 234432 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.993 0.981 – 1 0.227 32170 227335 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.769 0.592 – 0.999 0.0487 58 580 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.07 0.911 – 1.26 0.404 164 1635 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.96 0.834 – 1.1 0.566 210 2105 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.02 0.985 – 1.05 0.275 3716 37179 exclusion phecode
274.1 Gout Endocrine/metabolic 1.03 0.992 – 1.07 0.123 3166 31669 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.12 0.927 – 1.36 0.232 112 1119 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.96 0.884 – 1.04 0.325 610 6107 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.97 0.891 – 1.06 0.492 556 5563 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1 0.956 – 1.05 0.995 2068 21011 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 1.05 0.97 – 1.14 0.228 650 6522 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 0.962 0.865 – 1.07 0.471 353 3733 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.972 0.915 – 1.03 0.344 1184 11987 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.02 0.87 – 1.19 0.848 169 1714 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.01 0.988 – 1.04 0.306 7130 72727 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.03 1 – 1.07 0.0526 3998 40806 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.04 0.914 – 1.19 0.534 237 2405 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.06 1.01 – 1.12 0.0171 1775 18143 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1 0.939 – 1.07 0.924 945 9713 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.04 0.986 – 1.1 0.147 1395 14183 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.02 0.961 – 1.09 0.496 1147 11597 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.03 0.964 – 1.09 0.408 1043 10549 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 0.987 0.817 – 1.19 0.893 112 1125 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 0.969 0.932 – 1.01 0.11 2747 28191 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.07 0.973 – 1.19 0.155 446 4532 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 0.962 0.803 – 1.15 0.674 127 1273 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 0.996 0.93 – 1.07 0.915 883 8945 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.936 0.841 – 1.04 0.226 361 3603 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.956 0.836 – 1.09 0.509 229 2295 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.795 0.613 – 1.03 0.0835 52 519 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.01 0.995 – 1.03 0.152 10746 107897 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.01 0.995 – 1.04 0.145 10584 106281 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 0.879 0.703 – 1.1 0.258 84 834 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.13 0.866 – 1.47 0.374 65 659 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.953 0.838 – 1.08 0.468 248 2502 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 0.938 0.814 – 1.08 0.372 208 2093 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.872 0.734 – 1.04 0.118 138 1382 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.08 0.951 – 1.24 0.228 248 2476 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1 0.978 – 1.03 0.909 7559 75913 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1 0.977 – 1.03 0.945 7266 72905 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.04 0.942 – 1.14 0.456 444 4530 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.01 0.947 – 1.07 0.816 1102 11095 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1 0.939 – 1.06 0.997 1056 10639 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1 0.93 – 1.08 0.942 742 7487 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.969 0.835 – 1.12 0.676 176 1765 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 0.977 0.842 – 1.13 0.765 181 1836 exclusion phecode
281.9 Deficiency anemias Hematopoietic 0.844 0.647 – 1.1 0.21 54 536 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 0.891 0.758 – 1.05 0.162 149 1490 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 0.864 0.666 – 1.12 0.273 55 557 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.909 0.729 – 1.13 0.399 84 845 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.12 0.937 – 1.34 0.212 133 1374 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.05 0.856 – 1.28 0.647 101 1056 exclusion phecode
284 Aplastic anemia Hematopoietic 1.05 0.949 – 1.16 0.353 427 4340 exclusion phecode
285 Other anemias Hematopoietic 1 0.986 – 1.02 0.639 11856 120730 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.06 0.933 – 1.2 0.373 270 2697 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.06 0.975 – 1.14 0.18 657 6958 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.06 0.953 – 1.18 0.283 375 4136 exclusion phecode
286 Coagulation defects Hematopoietic 1.05 0.984 – 1.13 0.132 914 9184 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 1.03 0.936 – 1.14 0.527 455 4571 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.983 0.796 – 1.21 0.871 94 953 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.03 0.916 – 1.17 0.587 293 2931 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.05 0.814 – 1.35 0.718 62 628 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.837 0.672 – 1.04 0.113 86 860 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.13 1.01 – 1.26 0.0294 383 3852 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.04 0.987 – 1.09 0.146 1623 16479 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.12 0.928 – 1.34 0.244 129 1285 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.04 0.984 – 1.09 0.17 1524 15496 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.09 0.987 – 1.2 0.0874 417 4180 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.06 0.832 – 1.34 0.647 72 748 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.04 1.01 – 1.08 0.0126 3640 37541 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.05 1.01 – 1.09 0.0149 3058 31597 exclusion phecode
288.11 Neutropenia Hematopoietic 1.05 1.01 – 1.09 0.0141 3066 31677 exclusion phecode
288.3 Eosinophilia Hematopoietic 1.1 0.86 – 1.4 0.461 70 705 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.02 0.947 – 1.09 0.655 857 8589 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.06 0.937 – 1.19 0.375 289 2887 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.02 0.982 – 1.07 0.268 2564 25985 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1.11 1.01 – 1.22 0.024 507 5142 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.02 0.904 – 1.14 0.793 292 2914 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 0.898 0.729 – 1.11 0.309 87 898 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.965 0.921 – 1.01 0.136 1920 19215 exclusion phecode
290.1 Dementias Mental Disorders 0.958 0.898 – 1.02 0.189 999 9999 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.92 0.833 – 1.02 0.103 428 4291 exclusion phecode
290.16 Vascular dementia Mental Disorders 0.955 0.827 – 1.1 0.533 200 2005 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.945 0.872 – 1.02 0.165 646 6482 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.07 0.839 – 1.38 0.569 70 708 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.03 0.958 – 1.11 0.432 831 8366 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.04 0.87 – 1.23 0.693 130 1313 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.03 0.908 – 1.16 0.68 286 2861 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.04 0.939 – 1.15 0.469 433 4367 exclusion phecode
292 Neurological disorders Mental Disorders 0.996 0.966 – 1.03 0.783 4586 46135 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.01 0.953 – 1.06 0.85 1497 15042 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 1.08 0.923 – 1.26 0.35 190 1900 exclusion phecode
292.3 Memory loss Mental Disorders 0.966 0.893 – 1.04 0.382 693 6966 exclusion phecode
292.4 Altered mental status Mental Disorders 1.01 0.964 – 1.05 0.745 2159 21761 exclusion phecode
292.6 Hallucinations Mental Disorders 0.969 0.864 – 1.09 0.594 302 3063 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 0.965 0.923 – 1.01 0.12 2074 20744 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.07 1 – 1.15 0.0477 898 8972 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.996 0.928 – 1.07 0.914 837 8430 exclusion phecode
295.1 Schizophrenia Mental Disorders 0.987 0.906 – 1.08 0.769 572 5760 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.09 0.934 – 1.27 0.282 176 1774 exclusion phecode
295.3 Psychosis Mental Disorders 1.08 0.925 – 1.27 0.319 168 1705 exclusion phecode
296 Mood disorders Mental Disorders 1.01 0.99 – 1.03 0.374 12280 123402 exclusion phecode
296.1 Bipolar Mental Disorders 0.992 0.932 – 1.06 0.806 1053 10564 exclusion phecode
296.2 Depression Mental Disorders 1.01 0.992 – 1.03 0.279 11650 117070 exclusion phecode
296.22 Major depressive disorder Mental Disorders 0.966 0.869 – 1.07 0.519 359 3591 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.955 0.851 – 1.07 0.426 311 3066 exclusion phecode
300 Anxiety disorders Mental Disorders 1 0.98 – 1.03 0.7 6796 68244 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1 0.979 – 1.03 0.719 6280 63054 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 0.87 0.739 – 1.02 0.095 149 1495 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.989 0.917 – 1.07 0.777 701 7053 exclusion phecode
300.13 Phobia Mental Disorders 1.02 0.934 – 1.12 0.624 498 4988 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.11 0.928 – 1.33 0.253 138 1403 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.39 1.04 – 1.86 0.0261 53 527 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 0.911 0.764 – 1.09 0.305 123 1232 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.01 0.834 – 1.22 0.918 113 1126 exclusion phecode
301 Personality disorders Mental Disorders 1.01 0.907 – 1.13 0.811 332 3332 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.96 0.794 – 1.16 0.675 118 1183 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 0.888 0.791 – 0.997 0.0436 283 2845 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.969 0.881 – 1.07 0.518 463 4662 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.973 0.872 – 1.09 0.62 347 3502 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.926 0.775 – 1.11 0.398 122 1221 exclusion phecode
304 Adjustment reaction Mental Disorders 1.1 0.975 – 1.24 0.122 293 2928 exclusion phecode
305.2 Eating disorder Mental Disorders 1.07 0.858 – 1.33 0.547 90 895 exclusion phecode
306 Other mental disorder Mental Disorders 1.01 0.995 – 1.02 0.256 27885 229389 exclusion phecode
306.9 Tension headache Mental Disorders 0.958 0.852 – 1.08 0.466 312 3142 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.891 0.705 – 1.13 0.335 75 770 exclusion phecode
313.3 Autism Mental Disorders 0.948 0.711 – 1.26 0.715 52 538 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.06 0.944 – 1.18 0.343 347 3502 exclusion phecode
315.1 Learning disorder Mental Disorders 0.967 0.821 – 1.14 0.684 160 1608 exclusion phecode
315.2 Speech and language disorder Mental Disorders 1.07 0.857 – 1.34 0.548 87 877 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.01 0.977 – 1.03 0.717 5299 53060 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.848 0.645 – 1.11 0.238 55 597 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1 0.983 – 1.02 0.879 12655 126644 exclusion phecode
317.1 Alcoholism Mental Disorders 0.998 0.976 – 1.02 0.84 8858 88737 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 0.944 0.88 – 1.01 0.108 835 8379 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.01 0.99 – 1.02 0.485 19253 185022 exclusion phecode
320 Meningitis Neurological 0.983 0.892 – 1.08 0.721 444 4437 exclusion phecode
323 Encephalitis Neurological 1.05 0.94 – 1.17 0.388 339 3413 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 1.13 0.888 – 1.44 0.317 73 738 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 0.936 0.834 – 1.05 0.267 292 2910 exclusion phecode
327 Sleep disorders Neurological 0.993 0.935 – 1.05 0.822 1159 11630 exclusion phecode
327.3 Sleep apnea Neurological 0.984 0.954 – 1.01 0.302 4420 44237 exclusion phecode
327.4 Insomnia Neurological 1.15 0.98 – 1.36 0.0851 161 1650 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.27 1.06 – 1.53 0.00876 134 1380 exclusion phecode
331 Other cerebral degenerations Neurological 0.979 0.921 – 1.04 0.493 1133 11387 exclusion phecode
331.1 Hydrocephalus Neurological 0.998 0.909 – 1.1 0.96 497 4999 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 0.992 0.898 – 1.1 0.867 428 4291 exclusion phecode
332 Parkinson's disease Neurological 0.974 0.916 – 1.04 0.397 1123 11220 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1 0.935 – 1.07 0.945 887 8929 exclusion phecode
333.1 Essential tremor Neurological 0.945 0.825 – 1.08 0.414 215 2154 exclusion phecode
333.2 Myoclonus Neurological 0.943 0.766 – 1.16 0.578 95 956 exclusion phecode
333.4 Torsion dystonia Neurological 0.995 0.874 – 1.13 0.934 250 2516 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 0.985 0.939 – 1.03 0.547 1801 18094 exclusion phecode
334.1 Spinocerebellar disease Neurological 0.981 0.811 – 1.19 0.845 115 1164 exclusion phecode
334.2 Anterior horn cell disease Neurological 1.07 0.935 – 1.22 0.332 245 2441 exclusion phecode
335 Multiple sclerosis Neurological 0.963 0.91 – 1.02 0.182 1334 13331 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 0.969 0.853 – 1.1 0.629 265 2661 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 0.817 0.645 – 1.03 0.093 72 718 exclusion phecode
338 Pain Neurological 1.06 0.984 – 1.14 0.125 765 7671 exclusion phecode
338.1 Acute pain Neurological 1.02 0.92 – 1.13 0.705 392 3924 exclusion phecode
338.2 Chronic pain Neurological 1.09 0.978 – 1.21 0.121 379 3808 exclusion phecode
339 Other headache syndromes Neurological 1.01 0.985 – 1.03 0.507 7760 77957 exclusion phecode
340 Migraine Neurological 1.02 0.986 – 1.07 0.214 2837 28482 exclusion phecode
340.1 Migrain with aura Neurological 0.979 0.852 – 1.12 0.765 212 2108 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.994 0.876 – 1.13 0.929 250 2525 exclusion phecode
342 Hemiplegia Neurological 1.03 0.972 – 1.08 0.361 1484 14915 exclusion phecode
343 Infantile cerebral palsy Neurological 0.968 0.82 – 1.14 0.696 145 1448 exclusion phecode
344 Other paralytic syndromes Neurological 0.993 0.917 – 1.08 0.862 654 6574 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.994 0.965 – 1.02 0.67 4990 50142 exclusion phecode
345.1 Epilepsy Neurological 0.944 0.88 – 1.01 0.107 861 8633 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 0.965 0.875 – 1.06 0.47 437 4369 exclusion phecode
345.12 Partial epilepsy Neurological 0.908 0.802 – 1.03 0.129 276 2770 exclusion phecode
345.3 Convulsions Neurological 0.964 0.923 – 1.01 0.0994 2219 22288 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.15 0.968 – 1.38 0.111 139 1430 exclusion phecode
348 Other conditions of brain Neurological 1 0.932 – 1.08 0.928 772 7788 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.01 0.891 – 1.14 0.883 265 2669 exclusion phecode
348.4 Cerebral cysts Neurological 1.09 0.91 – 1.3 0.361 132 1346 exclusion phecode
348.7 Coma Neurological 1.05 0.938 – 1.17 0.406 356 3586 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.03 0.901 – 1.17 0.678 247 2499 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.11 0.993 – 1.23 0.0661 386 3887 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.01 0.902 – 1.13 0.862 337 3403 exclusion phecode
350 Abnormal movement Neurological 0.979 0.941 – 1.02 0.308 2645 26637 exclusion phecode
350.1 Abnormal involuntary movements Neurological 0.905 0.844 – 0.97 0.00485 881 8823 exclusion phecode
350.2 Abnormality of gait Neurological 0.993 0.944 – 1.05 0.791 1577 15919 exclusion phecode
350.3 Lack of coordination Neurological 1.05 0.943 – 1.17 0.364 362 3630 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.913 0.692 – 1.2 0.521 53 539 exclusion phecode
351 Other peripheral nerve disorders Neurological 0.996 0.978 – 1.01 0.694 12366 123773 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.03 0.974 – 1.09 0.302 1359 13656 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.1 0.997 – 1.21 0.0572 459 4622 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.01 0.939 – 1.08 0.848 873 8761 exclusion phecode
353 Nerve root and plexus disorders Neurological 0.978 0.92 – 1.04 0.47 1123 11278 exclusion phecode
353.1 Nerve plexus lesions Neurological 1.01 0.835 – 1.23 0.898 113 1138 exclusion phecode
353.2 Nerve root lesions Neurological 1.08 0.819 – 1.43 0.578 56 566 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.959 0.813 – 1.13 0.622 151 1517 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.03 0.969 – 1.08 0.383 1350 13615 exclusion phecode
358 Myoneural disorders Neurological 0.977 0.848 – 1.13 0.746 211 2099 exclusion phecode
358.1 Myasthenia gravis Neurological 0.96 0.827 – 1.12 0.595 192 1911 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.992 0.903 – 1.09 0.872 461 4634 exclusion phecode
359.1 Muscular dystrophies Neurological 0.872 0.727 – 1.05 0.142 121 1217 exclusion phecode
359.2 Myopathy Neurological 1.04 0.933 – 1.16 0.492 357 3588 exclusion phecode
360 Disorders of the globe Sense Organs 0.99 0.888 – 1.1 0.858 337 3353 exclusion phecode
360.2 Progressive myopia Sense Organs 0.929 0.82 – 1.05 0.25 251 2499 exclusion phecode
361 Retinal detachments and defects Sense Organs 1.01 0.977 – 1.05 0.482 3236 32363 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.996 0.942 – 1.05 0.895 1387 13847 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 1.02 0.814 – 1.29 0.836 68 678 exclusion phecode
362 Other retinal disorders Sense Organs 0.996 0.964 – 1.03 0.832 3816 38220 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.03 0.988 – 1.08 0.155 2163 21702 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.03 0.987 – 1.08 0.161 2160 21672 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.02 0.864 – 1.19 0.849 161 1605 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1 0.816 – 1.23 0.98 99 986 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.968 0.903 – 1.04 0.361 847 8452 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 1.08 0.927 – 1.27 0.318 182 1821 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.915 0.732 – 1.14 0.435 81 810 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.02 0.847 – 1.24 0.805 116 1153 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.958 0.815 – 1.13 0.606 168 1694 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.854 0.666 – 1.1 0.216 69 688 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.974 0.898 – 1.06 0.519 644 6458 exclusion phecode
364.1 Corneal opacity Sense Organs 0.954 0.771 – 1.18 0.669 90 908 exclusion phecode
364.2 Corneal edema Sense Organs 0.833 0.674 – 1.03 0.0926 79 798 exclusion phecode
364.4 Corneal degenerations Sense Organs 1.08 0.932 – 1.26 0.299 200 2009 exclusion phecode
364.41 Keratoconus Sense Organs 0.919 0.741 – 1.14 0.442 86 868 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.936 0.814 – 1.08 0.354 210 2101 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.997 0.809 – 1.23 0.979 100 998 exclusion phecode
365 Glaucoma Sense Organs 1.01 0.983 – 1.05 0.372 4380 43962 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 1.02 0.957 – 1.09 0.557 1022 10313 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 1.02 0.953 – 1.08 0.643 1016 10252 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.02 0.943 – 1.1 0.634 696 6965 exclusion phecode
366 Cataract Sense Organs 0.991 0.977 – 1.01 0.237 19835 168058 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 1.13 0.89 – 1.44 0.313 69 697 exclusion phecode
366.2 Senile cataract Sense Organs 0.994 0.972 – 1.02 0.629 8192 81550 exclusion phecode
366.3 Traumatic cataract Sense Organs 1.09 0.886 – 1.33 0.428 102 1017 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.964 0.924 – 1 0.0825 2396 24003 exclusion phecode
367.1 Myopia Sense Organs 0.97 0.915 – 1.03 0.297 1244 12459 exclusion phecode
367.2 Astigmatism Sense Organs 0.843 0.73 – 0.974 0.0207 190 1889 exclusion phecode
367.8 Hypermetropia Sense Organs 0.991 0.869 – 1.13 0.895 252 2521 exclusion phecode
367.9 Blindness and low vision Sense Organs 0.974 0.903 – 1.05 0.5 716 7180 exclusion phecode
368 Visual disturbances Sense Organs 0.996 0.959 – 1.03 0.841 2945 29533 exclusion phecode
368.1 Amblyopia Sense Organs 0.985 0.9 – 1.08 0.735 531 5296 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1 0.93 – 1.08 0.928 723 7268 exclusion phecode
368.3 Anisometropia Sense Organs 0.909 0.772 – 1.07 0.251 154 1546 exclusion phecode
368.4 Visual field defects Sense Organs 0.952 0.851 – 1.07 0.393 330 3311 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 1 0.924 – 1.09 0.938 608 6090 exclusion phecode
369 Infection of the eye Sense Organs 1.02 0.931 – 1.11 0.681 549 5520 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.985 0.824 – 1.18 0.867 124 1249 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 1.08 0.936 – 1.25 0.289 211 2121 exclusion phecode
370 Keratitis Sense Organs 1.08 0.952 – 1.22 0.241 285 2844 exclusion phecode
370.1 Corneal ulcer Sense Organs 1.06 0.889 – 1.26 0.525 140 1403 exclusion phecode
371 Inflammation of the eye Sense Organs 0.994 0.957 – 1.03 0.734 3035 30384 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.981 0.894 – 1.08 0.687 480 4808 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.995 0.953 – 1.04 0.807 2346 23464 exclusion phecode
372 Disorders of conjunctiva Sense Organs 0.982 0.911 – 1.06 0.629 758 7572 exclusion phecode
374 Other disorders of eyelids Sense Organs 1.01 0.986 – 1.04 0.334 5653 56595 exclusion phecode
374.1 Ectropion or entropion Sense Organs 1 0.941 – 1.07 0.949 1057 10609 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 1.02 0.977 – 1.08 0.32 1818 18152 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.995 0.952 – 1.04 0.827 2193 21911 exclusion phecode
375.2 Epiphora Sense Organs 1.04 0.972 – 1.12 0.251 894 8928 exclusion phecode
376 Disorders of the orbit Sense Organs 0.897 0.72 – 1.12 0.334 86 856 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.03 0.923 – 1.15 0.607 359 3604 exclusion phecode
377.1 Optic atrophy Sense Organs 1.11 0.849 – 1.46 0.438 56 566 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.05 0.873 – 1.26 0.624 123 1244 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.01 0.958 – 1.07 0.679 1406 14079 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.01 0.94 – 1.08 0.86 907 9060 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.94 0.819 – 1.08 0.381 213 2137 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.02 0.897 – 1.15 0.794 274 2749 exclusion phecode
379 Other disorders of eye Sense Organs 0.993 0.96 – 1.03 0.691 3691 36916 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.981 0.928 – 1.04 0.501 1363 13609 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.978 0.933 – 1.03 0.37 1808 18059 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 0.89 0.698 – 1.13 0.347 71 709 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.04 0.935 – 1.15 0.483 399 4022 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.03 0.88 – 1.21 0.686 167 1688 exclusion phecode
380 Disorders of external ear Sense Organs 1.01 0.932 – 1.1 0.807 640 6389 exclusion phecode
380.1 Otitis externa Sense Organs 0.932 0.854 – 1.02 0.119 507 5088 exclusion phecode
380.4 Impacted cerumen Sense Organs 1.01 0.909 – 1.13 0.809 360 3599 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.98 0.938 – 1.02 0.358 2137 21421 exclusion phecode
381.1 Otitis media Sense Organs 0.982 0.935 – 1.03 0.453 1757 17615 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.959 0.894 – 1.03 0.244 849 8499 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.977 0.844 – 1.13 0.755 190 1923 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.949 0.812 – 1.11 0.509 171 1705 exclusion phecode
381.9 Otorrhea Sense Organs 0.935 0.827 – 1.06 0.288 279 2797 exclusion phecode
382 Otalgia Sense Organs 1.08 0.959 – 1.22 0.205 305 3071 exclusion phecode
383 Otosclerosis Sense Organs 1.03 0.915 – 1.15 0.648 308 3078 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.04 0.977 – 1.1 0.239 1294 12947 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.05 0.984 – 1.12 0.143 1040 10394 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.03 0.96 – 1.11 0.392 779 7812 exclusion phecode
385.3 Cholesteatoma Sense Organs 1 0.922 – 1.09 0.97 603 6061 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.11 0.968 – 1.27 0.136 241 2395 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.998 0.95 – 1.05 0.944 1725 17310 exclusion phecode
386.1 Meniere's disease Sense Organs 0.956 0.878 – 1.04 0.302 572 5741 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 1.02 0.915 – 1.13 0.734 374 3753 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.01 0.936 – 1.09 0.835 760 7635 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.01 0.977 – 1.04 0.629 4556 45668 exclusion phecode
388 Other disorders of ear Sense Organs 1.01 0.872 – 1.17 0.912 201 2008 exclusion phecode
389 Hearing loss Sense Organs 0.997 0.965 – 1.03 0.831 4156 41810 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.935 0.851 – 1.03 0.16 452 4542 exclusion phecode
389.2 Conductive hearing loss Sense Organs 0.847 0.77 – 0.932 0.000635 445 4480 exclusion phecode
389.4 Tinnitus Sense Organs 1.02 0.932 – 1.12 0.643 505 5126 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.02 0.986 – 1.05 0.295 4879 48836 exclusion phecode
394.2 Mitral valve disease Circulatory System 1 0.966 – 1.04 0.871 2980 29842 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.04 0.98 – 1.1 0.206 1279 12774 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.02 0.96 – 1.09 0.487 1053 10537 exclusion phecode
395 Heart valve disorders Circulatory System 1.01 0.976 – 1.04 0.646 4206 42105 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.01 0.968 – 1.05 0.759 2878 28826 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.982 0.871 – 1.11 0.773 276 2757 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.16 0.952 – 1.42 0.14 105 1036 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.851 0.694 – 1.04 0.119 96 967 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.01 0.954 – 1.06 0.798 1491 14912 exclusion phecode
396 Abnormal heart sounds Circulatory System 0.987 0.926 – 1.05 0.688 1038 10412 exclusion phecode
401 Hypertension Circulatory System 1.01 1 – 1.02 0.0439 73571 266162 exclusion phecode
401.1 Essential hypertension Circulatory System 1.01 1 – 1.02 0.0438 73348 265945 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.02 0.977 – 1.07 0.308 1882 18975 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 0.965 0.866 – 1.07 0.517 370 3690 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.04 0.986 – 1.1 0.147 1527 15432 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.03 0.861 – 1.22 0.78 142 1434 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 0.975 0.924 – 1.03 0.345 1472 14747 exclusion phecode
411 Ischemic Heart Disease Circulatory System 0.995 0.983 – 1.01 0.435 31158 210040 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.976 0.949 – 1 0.0926 5139 51385 exclusion phecode
411.2 Myocardial infarction Circulatory System 0.979 0.961 – 0.998 0.0267 11921 112495 exclusion phecode
411.3 Angina pectoris Circulatory System 0.993 0.977 – 1.01 0.396 15835 143328 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 0.984 0.97 – 0.999 0.0356 20134 154273 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.05 0.971 – 1.13 0.226 697 6981 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.991 0.974 – 1.01 0.267 15236 131466 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1 0.948 – 1.07 0.875 1213 12149 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 0.972 0.927 – 1.02 0.248 1815 18184 exclusion phecode
414.2 ASCVD Circulatory System 1.06 0.839 – 1.33 0.637 72 718 exclusion phecode
415 Pulmonary heart disease Circulatory System 0.999 0.968 – 1.03 0.941 4390 44676 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.14 0.895 – 1.46 0.288 75 747 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.98 0.902 – 1.07 0.642 598 5984 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.01 0.914 – 1.11 0.874 445 4458 exclusion phecode
416 Cardiomegaly Circulatory System 0.987 0.949 – 1.03 0.515 2675 26745 exclusion phecode
418 Nonspecific chest pain Circulatory System 0.988 0.976 – 1 0.0497 28480 269211 exclusion phecode
418.1 Precordial pain Circulatory System 0.973 0.94 – 1.01 0.116 3535 35427 exclusion phecode
420 Carditis Circulatory System 1.01 0.968 – 1.06 0.59 2092 21003 exclusion phecode
420.1 Myocarditis Circulatory System 1.03 0.858 – 1.23 0.761 127 1265 exclusion phecode
420.2 Pericarditis Circulatory System 1 0.946 – 1.06 0.981 1330 13338 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.04 0.909 – 1.2 0.553 222 2220 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.1 0.902 – 1.35 0.34 113 1126 exclusion phecode
420.3 Endocarditis Circulatory System 1.01 0.936 – 1.09 0.762 711 7181 exclusion phecode
425 Cardiomyopathy Circulatory System 0.998 0.942 – 1.06 0.938 1265 12677 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.989 0.933 – 1.05 0.722 1231 12329 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.954 0.802 – 1.13 0.593 132 1328 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.951 0.81 – 1.12 0.544 163 1626 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.12 0.861 – 1.47 0.39 60 600 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.01 0.989 – 1.04 0.296 6886 68994 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.03 0.989 – 1.08 0.14 2108 21123 exclusion phecode
426.21 First degree AV block Circulatory System 1.04 0.978 – 1.11 0.197 986 9850 exclusion phecode
426.23 Second degree AV block Circulatory System 0.944 0.856 – 1.04 0.243 449 4502 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1.07 0.982 – 1.17 0.12 585 5855 exclusion phecode
426.25 Other heart block Circulatory System 1.03 0.864 – 1.24 0.721 131 1314 exclusion phecode
426.3 Bundle branch block Circulatory System 0.994 0.959 – 1.03 0.723 3322 33278 exclusion phecode
426.31 Right bundle branch block Circulatory System 1 0.951 – 1.06 0.889 1489 14898 exclusion phecode
426.32 Left bundle branch block Circulatory System 0.98 0.933 – 1.03 0.429 1741 17458 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.894 0.784 – 1.02 0.0927 233 2322 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.03 0.79 – 1.34 0.838 60 599 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.04 0.999 – 1.09 0.0533 2469 24725 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.03 0.987 – 1.08 0.17 2268 22720 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.01 1 – 1.03 0.0422 24095 205351 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.02 0.986 – 1.06 0.228 3186 31933 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.03 0.984 – 1.07 0.218 2333 23407 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.99 0.926 – 1.06 0.779 933 9351 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.01 0.993 – 1.03 0.269 14575 133147 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.979 0.944 – 1.01 0.24 3217 32208 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.981 0.925 – 1.04 0.524 1189 11897 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.984 0.881 – 1.1 0.779 344 3433 exclusion phecode
427.42 Cardiac arrest Circulatory System 0.987 0.925 – 1.05 0.686 986 9870 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.02 0.958 – 1.1 0.474 949 9514 exclusion phecode
427.6 Premature beats Circulatory System 1.05 0.957 – 1.14 0.319 533 5347 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 0.997 0.831 – 1.2 0.973 116 1164 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.06 1.01 – 1.11 0.015 2161 21793 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.968 0.874 – 1.07 0.537 399 4011 exclusion phecode
427.9 Palpitations Circulatory System 1.02 0.986 – 1.05 0.248 3793 37951 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.988 0.961 – 1.02 0.377 5590 55917 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 0.976 0.934 – 1.02 0.284 2108 21071 exclusion phecode
428.2 Heart failure NOS Circulatory System 0.999 0.969 – 1.03 0.962 4441 44442 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.05 0.967 – 1.13 0.262 715 7151 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.12 0.857 – 1.45 0.414 64 639 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.04 0.949 – 1.14 0.413 521 5199 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.06 0.914 – 1.23 0.45 196 1973 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.06 1.01 – 1.12 0.0117 1876 18773 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.09 1.01 – 1.17 0.0242 831 8322 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.09 1.01 – 1.17 0.0354 764 7635 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.01 0.894 – 1.15 0.836 266 2662 exclusion phecode
433 Cerebrovascular disease Circulatory System 1 0.982 – 1.03 0.737 8702 87207 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.979 0.922 – 1.04 0.48 1184 11807 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.02 0.889 – 1.17 0.772 226 2263 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1 0.968 – 1.03 0.979 4209 42212 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1 0.953 – 1.05 0.921 1670 16747 exclusion phecode
433.3 Cerebral ischemia Circulatory System 0.989 0.952 – 1.03 0.58 2882 28903 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 0.996 0.952 – 1.04 0.842 2128 21325 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.13 1.02 – 1.26 0.0252 390 3922 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1 0.945 – 1.06 0.977 1272 12747 exclusion phecode
440 Atherosclerosis Circulatory System 1.03 0.971 – 1.09 0.354 1373 13797 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.1 0.905 – 1.33 0.348 112 1126 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.07 0.991 – 1.15 0.0868 802 8055 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 0.895 0.797 – 1.01 0.063 285 2863 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.05 0.959 – 1.14 0.312 604 6134 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.06 0.932 – 1.2 0.397 277 2815 exclusion phecode
442 Other aneurysm Circulatory System 1.05 1 – 1.11 0.0304 1887 18922 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.04 0.984 – 1.1 0.171 1457 14603 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.992 0.928 – 1.06 0.822 930 9330 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.02 0.832 – 1.24 0.876 102 1018 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.06 0.904 – 1.24 0.479 168 1693 exclusion phecode
442.4 Arterial dissection Circulatory System 1.22 0.93 – 1.6 0.151 54 549 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.13 0.974 – 1.3 0.109 200 2018 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.01 0.98 – 1.05 0.442 3898 39169 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.04 0.98 – 1.11 0.187 1136 11392 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.06 0.953 – 1.18 0.287 382 3874 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.01 0.979 – 1.05 0.455 3665 36803 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.993 0.953 – 1.03 0.732 2567 25792 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 0.994 0.929 – 1.06 0.857 914 9231 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.02 0.934 – 1.11 0.669 551 5546 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.01 0.936 – 1.08 0.89 814 8192 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.928 0.801 – 1.08 0.322 188 1871 exclusion phecode
446.5 Giant cell arteritis Circulatory System 0.99 0.892 – 1.1 0.851 384 3862 exclusion phecode
446.9 Arteritis NOS Circulatory System 0.979 0.857 – 1.12 0.751 235 2391 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.01 0.957 – 1.07 0.653 1321 13279 exclusion phecode
447.1 Stricture of artery Circulatory System 1.04 0.966 – 1.11 0.317 865 8691 exclusion phecode
448 Disease of capillaries Circulatory System 0.92 0.776 – 1.09 0.336 140 1412 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.03 0.951 – 1.11 0.474 674 7014 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.978 0.946 – 1.01 0.177 3890 39578 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.98 0.947 – 1.01 0.235 3621 36881 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1.02 0.932 – 1.11 0.701 548 5630 exclusion phecode
454 Varicose veins Circulatory System 1.01 0.993 – 1.03 0.223 11135 111604 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1.01 0.988 – 1.03 0.454 11450 114798 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.04 0.954 – 1.12 0.401 621 6307 exclusion phecode
455 Hemorrhoids Circulatory System 1.01 0.992 – 1.02 0.435 23360 233857 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.956 0.827 – 1.11 0.545 184 1865 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.814 0.661 – 1 0.0538 96 964 exclusion phecode
458 Hypotension Circulatory System 0.994 0.967 – 1.02 0.646 5701 57600 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.04 0.979 – 1.1 0.22 1323 13333 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.08 0.941 – 1.25 0.265 229 2342 exclusion phecode
458.9 Hypotension NOS Circulatory System 0.977 0.944 – 1.01 0.199 3453 34907 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1 0.987 – 1.02 0.74 16126 160302 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 0.829 0.702 – 0.98 0.0281 141 1414 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1 0.988 – 1.02 0.608 15962 158936 exclusion phecode
464 Acute sinusitis Respiratory 0.924 0.802 – 1.07 0.28 196 1950 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.02 0.975 – 1.06 0.398 2246 22729 exclusion phecode
465.2 Acute pharyngitis Respiratory 1.05 0.978 – 1.13 0.179 821 8308 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.08 0.921 – 1.28 0.334 165 1643 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1 0.97 – 1.03 0.988 4642 46435 exclusion phecode
471 Nasal polyps Respiratory 0.988 0.953 – 1.02 0.495 3292 32919 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.05 0.984 – 1.13 0.135 955 9565 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.01 0.967 – 1.05 0.734 2548 25462 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.05 0.856 – 1.28 0.658 104 1037 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.904 0.8 – 1.02 0.106 263 2641 exclusion phecode
473.4 Voice disturbance Respiratory 1.02 0.954 – 1.08 0.623 1076 10760 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1 0.952 – 1.05 0.993 1761 17677 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.02 0.932 – 1.11 0.713 547 5471 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.972 0.914 – 1.03 0.373 1113 11173 exclusion phecode
475 Chronic sinusitis Respiratory 0.973 0.935 – 1.01 0.185 2576 25800 exclusion phecode
476 Allergic rhinitis Respiratory 0.991 0.93 – 1.06 0.791 1044 10542 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 0.999 0.958 – 1.04 0.965 2432 24383 exclusion phecode
478 Throat pain Respiratory 0.979 0.881 – 1.09 0.691 375 3774 exclusion phecode
479 Other upper respiratory disease Respiratory 0.999 0.968 – 1.03 0.973 4058 40631 exclusion phecode
480 Pneumonia Respiratory 1 0.984 – 1.02 0.691 10236 103097 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.01 0.988 – 1.04 0.288 6578 66219 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.01 0.988 – 1.04 0.278 5828 58694 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 0.883 0.716 – 1.09 0.243 92 927 exclusion phecode
480.2 Viral pneumonia Respiratory 1.11 0.873 – 1.42 0.387 72 718 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.906 0.741 – 1.11 0.335 98 987 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.999 0.928 – 1.08 0.98 787 7935 exclusion phecode
481 Influenza Respiratory 0.973 0.867 – 1.09 0.642 324 3272 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.01 0.874 – 1.17 0.891 191 1928 exclusion phecode
495 Asthma Respiratory 0.998 0.986 – 1.01 0.809 25543 249522 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.17 1.02 – 1.34 0.0204 248 2504 exclusion phecode
496 Chronic airway obstruction Respiratory 0.987 0.967 – 1.01 0.207 10360 101231 exclusion phecode
496.1 Emphysema Respiratory 0.956 0.91 – 1 0.0699 1729 17404 exclusion phecode
496.2 Chronic bronchitis Respiratory 0.984 0.948 – 1.02 0.418 2930 29408 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 0.998 0.959 – 1.04 0.932 2691 27005 exclusion phecode
496.3 Bronchiectasis Respiratory 0.951 0.907 – 0.997 0.0366 1874 18784 exclusion phecode
497 Bronchitis Respiratory 1.03 0.947 – 1.12 0.507 622 6246 exclusion phecode
500 Lung disease due to external agents Respiratory 0.948 0.859 – 1.05 0.289 411 4093 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.972 0.784 – 1.2 0.792 79 784 exclusion phecode
500.2 Pneumoconiosis Respiratory 0.948 0.831 – 1.08 0.422 243 2407 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1 0.927 – 1.09 0.92 650 6540 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.909 0.85 – 0.972 0.00556 911 9177 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.06 0.969 – 1.17 0.194 502 5065 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.938 0.84 – 1.05 0.253 326 3270 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.02 0.781 – 1.34 0.874 61 610 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.01 0.953 – 1.08 0.681 1119 11331 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 0.996 0.97 – 1.02 0.75 6253 64082 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.97 0.926 – 1.02 0.2 1970 19893 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.01 0.973 – 1.06 0.519 2581 25981 exclusion phecode
509.1 Respiratory failure Respiratory 1.03 0.986 – 1.08 0.173 2051 20670 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.02 0.975 – 1.07 0.348 1792 18071 exclusion phecode
509.5 Respiratory arrest Respiratory 0.903 0.765 – 1.07 0.23 142 1427 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.943 0.848 – 1.05 0.272 385 3854 exclusion phecode
510 Other diseases of lung Respiratory 0.989 0.918 – 1.07 0.78 752 7528 exclusion phecode
512 Other symptoms of respiratory system Respiratory 0.991 0.969 – 1.01 0.389 8940 90064 exclusion phecode
512.1 Wheezing Respiratory 0.929 0.814 – 1.06 0.275 219 2188 exclusion phecode
512.2 Painful respiration Respiratory 0.937 0.811 – 1.08 0.375 203 2071 exclusion phecode
512.7 Shortness of breath Respiratory 0.991 0.965 – 1.02 0.529 5783 58304 exclusion phecode
512.8 Cough Respiratory 1 0.963 – 1.04 0.974 2844 28554 exclusion phecode
512.9 Other dyspnea Respiratory 0.999 0.934 – 1.07 0.972 903 9099 exclusion phecode
513 Respiratory abnormalities Respiratory 1.01 0.933 – 1.1 0.744 610 6099 exclusion phecode
513.3 Hypoventilation Respiratory 0.932 0.746 – 1.16 0.536 83 829 exclusion phecode
513.4 Hyperventilation Respiratory 1.11 0.982 – 1.26 0.0927 277 2772 exclusion phecode
513.8 Disorders of diaphragm Respiratory 0.827 0.703 – 0.973 0.0222 153 1537 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1 0.961 – 1.04 0.945 2443 24591 exclusion phecode
516 Abnormal sputum Respiratory 1.02 0.976 – 1.07 0.374 2125 21283 exclusion phecode
516.1 Hemoptysis Respiratory 1.02 0.974 – 1.07 0.403 2066 20693 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.984 0.963 – 1 0.127 9276 93373 exclusion phecode
519.2 Respiratory complications Respiratory 1.01 0.903 – 1.14 0.817 322 3267 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.983 0.962 – 1 0.123 8770 88230 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.07 0.949 – 1.21 0.26 300 3035 exclusion phecode
520 Disorders of tooth development Digestive 0.983 0.939 – 1.03 0.452 2036 20297 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.11 0.832 – 1.49 0.471 53 528 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.986 0.945 – 1.03 0.511 2354 23469 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 0.982 0.946 – 1.02 0.338 3007 30124 exclusion phecode
521.1 Dental caries Digestive 0.982 0.946 – 1.02 0.338 3017 30233 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.03 0.981 – 1.08 0.225 1764 17690 exclusion phecode
522.5 Periapical abscess Digestive 0.993 0.936 – 1.05 0.82 1166 11698 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.02 0.97 – 1.07 0.445 1672 16753 exclusion phecode
523.1 Gingivitis Digestive 0.98 0.805 – 1.19 0.837 113 1125 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.02 0.963 – 1.09 0.448 1160 11611 exclusion phecode
523.31 Acute periodontitis Digestive 0.987 0.911 – 1.07 0.739 663 6653 exclusion phecode
523.32 Chronic periodontitis Digestive 1.01 0.93 – 1.11 0.748 557 5564 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.04 0.929 – 1.16 0.493 330 3303 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.965 0.86 – 1.08 0.543 304 3044 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.984 0.945 – 1.02 0.414 2659 26640 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.09 0.836 – 1.41 0.537 71 718 exclusion phecode
526 Diseases of the jaws Digestive 1 0.938 – 1.07 0.916 924 9246 exclusion phecode
526.1 Cysts of the jaws Digestive 0.943 0.842 – 1.06 0.311 328 3284 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.07 0.825 – 1.4 0.595 60 608 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.11 0.971 – 1.27 0.124 240 2390 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.09 0.947 – 1.25 0.234 233 2322 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.966 0.793 – 1.18 0.73 109 1095 exclusion phecode
526.9 Jaw disease NOS Digestive 1.03 0.898 – 1.18 0.689 232 2317 exclusion phecode
527 Diseases of the salivary glands Digestive 1.02 0.939 – 1.1 0.693 688 6917 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.14 0.904 – 1.44 0.27 84 835 exclusion phecode
527.2 Sialoadenitis Digestive 1.01 0.907 – 1.13 0.842 362 3637 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 0.975 0.762 – 1.25 0.842 62 616 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.01 0.843 – 1.22 0.877 119 1197 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.02 0.986 – 1.05 0.267 3852 38596 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.02 0.93 – 1.12 0.652 463 4657 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.02 0.918 – 1.13 0.739 385 3862 exclusion phecode
528.12 Oral aphthae Digestive 1.06 0.842 – 1.32 0.636 83 839 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.04 0.89 – 1.21 0.645 179 1782 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.994 0.829 – 1.19 0.945 122 1212 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.987 0.799 – 1.22 0.905 94 936 exclusion phecode
528.5 Diseases of lips Digestive 1.06 0.974 – 1.14 0.189 678 6789 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.07 0.948 – 1.21 0.273 306 3067 exclusion phecode
528.7 Sialolithiasis Digestive 1.01 0.895 – 1.13 0.923 313 3124 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 0.994 0.938 – 1.05 0.846 1228 12272 exclusion phecode
529.1 Glossitis Digestive 1.01 0.895 – 1.13 0.914 298 2979 exclusion phecode
530 Diseases of esophagus Digestive 1 0.99 – 1.01 0.76 33281 278233 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1 0.988 – 1.01 0.994 31093 271511 exclusion phecode
530.11 GERD Digestive 1 0.989 – 1.02 0.744 22510 225056 exclusion phecode
530.12 Ulcer of esophagus Digestive 0.998 0.97 – 1.03 0.888 5174 51943 exclusion phecode
530.14 Reflux esophagitis Digestive 0.991 0.971 – 1.01 0.366 10402 104181 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.985 0.936 – 1.04 0.558 1671 16761 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1.04 0.996 – 1.1 0.0723 1859 18644 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.08 0.989 – 1.17 0.0882 632 6341 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.06 0.903 – 1.26 0.457 151 1525 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.04 0.933 – 1.17 0.459 340 3413 exclusion phecode
530.9 Heartburn Digestive 1 0.956 – 1.05 0.98 2079 20790 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1 0.976 – 1.03 0.962 7070 70855 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.01 0.925 – 1.09 0.901 633 6364 exclusion phecode
531.2 Gastric ulcer Digestive 1.01 0.98 – 1.05 0.467 4072 40805 exclusion phecode
531.3 Duodenal ulcer Digestive 0.983 0.947 – 1.02 0.372 2986 29933 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.04 0.944 – 1.15 0.42 426 4258 exclusion phecode
532 Dysphagia Digestive 1 0.978 – 1.03 0.795 6396 64115 exclusion phecode
535 Gastritis and duodenitis Digestive 0.996 0.984 – 1.01 0.561 27951 260620 exclusion phecode
535.1 Acute gastritis Digestive 1.02 0.961 – 1.08 0.531 1178 11797 exclusion phecode
535.2 Atrophic gastritis Digestive 0.936 0.843 – 1.04 0.22 370 3678 exclusion phecode
535.6 Duodenitis Digestive 0.984 0.961 – 1.01 0.176 7561 75720 exclusion phecode
535.8 Other specified gastritis Digestive 1.01 0.985 – 1.03 0.484 8024 80467 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.01 0.835 – 1.21 0.949 120 1189 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.06 0.934 – 1.2 0.372 258 2565 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 0.989 0.955 – 1.02 0.55 3360 33790 exclusion phecode
540 Appendiceal conditions Digestive 1.01 0.978 – 1.05 0.441 3078 30782 exclusion phecode
540.1 Appendicitis Digestive 1.02 0.978 – 1.06 0.417 2885 28863 exclusion phecode
540.11 Acute appendicitis Digestive 1.02 0.977 – 1.06 0.405 2592 25928 exclusion phecode
550 Abdominal hernia Digestive 0.988 0.979 – 0.998 0.0233 45208 281733 exclusion phecode
550.1 Inguinal hernia Digestive 1.01 0.99 – 1.02 0.447 15787 123174 exclusion phecode
550.2 Diaphragmatic hernia Digestive 0.981 0.968 – 0.993 0.00272 26342 238098 exclusion phecode
550.3 Femoral hernia Digestive 1 0.926 – 1.09 0.93 645 6476 exclusion phecode
550.4 Umbilical hernia Digestive 0.962 0.93 – 0.995 0.0248 3695 37019 exclusion phecode
550.5 Ventral hernia Digestive 1.03 0.994 – 1.07 0.107 3375 34240 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.01 0.974 – 1.04 0.744 4428 44338 exclusion phecode
555.1 Regional enteritis Digestive 1.03 0.978 – 1.08 0.28 1730 17293 exclusion phecode
555.2 Ulcerative colitis Digestive 0.999 0.963 – 1.04 0.967 3163 31723 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.01 0.925 – 1.1 0.824 535 5370 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1 0.942 – 1.07 0.893 1053 10561 exclusion phecode
556.1 Ulceration of intestine Digestive 1.01 0.934 – 1.1 0.769 668 6693 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.865 0.77 – 0.972 0.0145 298 2976 exclusion phecode
557.1 Celiac disease Digestive 0.989 0.942 – 1.04 0.641 1820 18332 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.02 1 – 1.03 0.0489 15368 154673 exclusion phecode
559 Ileostomy status Digestive 0.977 0.929 – 1.03 0.374 1611 16498 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.01 0.98 – 1.05 0.449 3778 39227 exclusion phecode
560.1 Paralytic ileus Digestive 0.997 0.91 – 1.09 0.954 508 5217 exclusion phecode
560.2 Impaction of intestine Digestive 1.06 0.932 – 1.2 0.389 266 2661 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.998 0.928 – 1.07 0.965 810 8295 exclusion phecode
560.4 Other intestinal obstruction Digestive 1.01 0.971 – 1.04 0.704 3211 33451 exclusion phecode
561 Symptoms involving digestive system Digestive 0.982 0.966 – 0.998 0.0322 15635 157203 exclusion phecode
561.1 Diarrhea Digestive 1 0.909 – 1.1 0.996 463 4640 exclusion phecode
561.2 Flatulence Digestive 0.99 0.941 – 1.04 0.683 1653 16819 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1 0.991 – 1.02 0.602 26561 211145 exclusion phecode
562.1 Diverticulosis Digestive 1 0.99 – 1.02 0.644 26519 211095 exclusion phecode
563 Constipation Digestive 0.994 0.974 – 1.01 0.586 10155 102836 exclusion phecode
564 Functional digestive disorders Digestive 1 0.986 – 1.01 0.971 21490 209405 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 0.995 0.968 – 1.02 0.729 5458 54939 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.02 0.967 – 1.07 0.503 1621 16416 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 0.999 0.983 – 1.02 0.919 15109 151297 exclusion phecode
565 Anal and rectal conditions Digestive 0.999 0.982 – 1.02 0.935 14659 147136 exclusion phecode
565.1 Anal and rectal polyp Digestive 1 0.976 – 1.02 0.991 7318 73350 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.04 0.967 – 1.11 0.315 911 9273 exclusion phecode
568 Other disorders of peritoneum Digestive 1.02 0.98 – 1.05 0.391 3186 32467 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.01 0.972 – 1.05 0.632 3031 30860 exclusion phecode
569 Other disorders of intestine Digestive 0.993 0.962 – 1.03 0.691 4126 41782 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.969 0.815 – 1.15 0.725 143 1474 exclusion phecode
569.2 Gastrointestinal complications Digestive 0.957 0.871 – 1.05 0.358 470 4852 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.01 0.97 – 1.05 0.695 2935 29556 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.02 0.97 – 1.07 0.445 1674 16871 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.989 0.815 – 1.2 0.911 113 1137 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 0.956 0.839 – 1.09 0.495 255 2558 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1 0.938 – 1.07 0.946 969 9782 exclusion phecode
571.81 Portal hypertension Digestive 1.03 0.939 – 1.12 0.56 527 5273 exclusion phecode
572 Ascites (non malignant) Digestive 1.02 0.968 – 1.08 0.408 1330 15409 exclusion phecode
573 Other disorders of liver Digestive 1.02 0.969 – 1.08 0.419 1472 14942 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.06 0.856 – 1.32 0.589 96 957 exclusion phecode
573.3 Hepatomegaly Digestive 0.962 0.856 – 1.08 0.52 296 2961 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1 0.933 – 1.07 0.99 891 8935 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 0.997 0.963 – 1.03 0.874 3429 34483 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 0.885 0.77 – 1.02 0.0883 206 2085 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 0.996 0.98 – 1.01 0.637 15507 155400 exclusion phecode
574.1 Cholelithiasis Digestive 0.99 0.973 – 1.01 0.289 13461 134909 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.981 0.93 – 1.03 0.479 1497 14989 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1 0.974 – 1.03 0.89 5403 54042 exclusion phecode
574.2 Calculus of bile duct Digestive 1.01 0.969 – 1.05 0.666 2597 26072 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.01 0.967 – 1.05 0.783 2734 27416 exclusion phecode
575 Other biliary tract disease Digestive 1.01 0.972 – 1.04 0.766 3836 38582 exclusion phecode
575.1 Cholangitis Digestive 1.02 0.929 – 1.12 0.668 489 4930 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.05 0.974 – 1.13 0.203 767 7737 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 1.01 0.912 – 1.11 0.919 457 4552 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1 0.949 – 1.06 0.938 1402 14046 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.02 0.953 – 1.08 0.623 1027 10320 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.919 0.826 – 1.02 0.121 342 3480 exclusion phecode
577 Diseases of pancreas Digestive 0.991 0.952 – 1.03 0.648 2657 26575 exclusion phecode
577.1 Acute pancreatitis Digestive 0.986 0.942 – 1.03 0.539 1993 19876 exclusion phecode
577.2 Chronic pancreatitis Digestive 0.932 0.853 – 1.02 0.114 514 5138 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.02 0.916 – 1.13 0.73 361 3635 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.992 – 1.02 0.417 20505 205637 exclusion phecode
578.1 Hematemesis Digestive 1.01 0.96 – 1.05 0.801 1933 19515 exclusion phecode
578.2 Blood in stool Digestive 1 0.962 – 1.04 0.944 2613 26214 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.01 0.989 – 1.03 0.446 13004 130330 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1 0.974 – 1.03 0.898 5250 52643 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.01 0.958 – 1.07 0.671 1439 15426 exclusion phecode
579.2 Splenomegaly Digestive 1.07 0.97 – 1.19 0.169 420 4237 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.98 0.932 – 1.03 0.44 1646 16484 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.02 0.971 – 1.08 0.374 1517 15303 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.01 0.943 – 1.07 0.852 1039 10505 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.799 0.635 – 1 0.0551 73 737 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.05 0.877 – 1.26 0.6 135 1352 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.02 0.954 – 1.1 0.511 864 8738 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.04 0.944 – 1.14 0.448 468 4685 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.951 0.834 – 1.08 0.455 245 2453 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.964 0.847 – 1.1 0.574 252 2523 exclusion phecode
585 Renal failure Genitourinary 1 0.98 – 1.03 0.752 6878 69589 exclusion phecode
585.1 Acute renal failure Genitourinary 1.01 0.982 – 1.04 0.44 4459 45202 exclusion phecode
585.2 Renal failure NOS Genitourinary 0.992 0.94 – 1.05 0.767 1433 14600 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.991 0.953 – 1.03 0.667 2617 26413 exclusion phecode
585.31 Renal dialysis Genitourinary 1.01 0.921 – 1.11 0.838 494 4942 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.02 0.981 – 1.05 0.38 3306 33506 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.969 0.84 – 1.12 0.665 204 2083 exclusion phecode
586.11 Small kidney Genitourinary 0.987 0.845 – 1.15 0.865 177 1795 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 0.994 0.938 – 1.05 0.826 1247 12559 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.09 0.873 – 1.36 0.443 80 798 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.02 0.95 – 1.09 0.618 879 9099 exclusion phecode
587 Kidney replaced by transpant Genitourinary 0.983 0.886 – 1.09 0.752 366 3678 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 0.973 0.792 – 1.2 0.793 97 984 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.04 0.86 – 1.26 0.689 113 1154 exclusion phecode
590 Pyelonephritis Genitourinary 1.03 0.976 – 1.09 0.263 1317 13227 exclusion phecode
591 Urinary tract infection Genitourinary 0.998 0.979 – 1.02 0.803 12236 123500 exclusion phecode
592 Cystitis and urethritis Genitourinary 0.993 0.956 – 1.03 0.707 2941 29569 exclusion phecode
592.1 Cystitis Genitourinary 0.999 0.961 – 1.04 0.945 2879 28948 exclusion phecode
592.11 Acute cystitis Genitourinary 0.934 0.789 – 1.11 0.426 138 1369 exclusion phecode
592.12 Chronic cystitis Genitourinary 0.919 0.858 – 0.983 0.0144 882 8867 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 0.924 0.81 – 1.05 0.239 247 2474 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.974 0.834 – 1.14 0.74 165 1655 exclusion phecode
593 Hematuria Genitourinary 1 0.985 – 1.02 0.869 15988 159776 exclusion phecode
594 Urinary calculus Genitourinary 0.987 0.962 – 1.01 0.332 6362 63655 exclusion phecode
594.1 Calculus of kidney Genitourinary 0.979 0.944 – 1.02 0.251 3169 31706 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.07 0.996 – 1.16 0.0644 776 7750 exclusion phecode
594.3 Calculus of ureter Genitourinary 0.961 0.922 – 1 0.0615 2396 23987 exclusion phecode
594.8 Renal colic Genitourinary 0.951 0.91 – 0.995 0.0286 2046 20463 exclusion phecode
595 Hydronephrosis Genitourinary 1.01 0.961 – 1.06 0.76 1847 19346 exclusion phecode
596 Other disorders of bladder Genitourinary 1.02 0.995 – 1.04 0.131 9724 97567 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.04 0.99 – 1.09 0.122 1969 19685 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1 0.95 – 1.05 0.991 1644 16517 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.02 0.987 – 1.05 0.235 3889 39016 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.01 0.977 – 1.05 0.501 3303 33043 exclusion phecode
597.2 Urinary complications NEC Genitourinary 0.955 0.754 – 1.21 0.705 76 774 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.02 0.986 – 1.06 0.236 3514 35226 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.985 0.876 – 1.11 0.807 299 3028 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.999 0.984 – 1.01 0.911 18277 183650 exclusion phecode
599.1 Urinary obstruction Genitourinary 1.26 1.07 – 1.49 0.00661 162 1667 exclusion phecode
599.2 Retention of urine Genitourinary 1 0.978 – 1.03 0.845 6676 67074 exclusion phecode
599.3 Dysuria Genitourinary 1.02 0.961 – 1.08 0.509 1189 11932 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.985 0.964 – 1.01 0.187 8663 87023 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.02 0.992 – 1.06 0.147 3999 40045 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1 0.824 – 1.22 0.973 104 1058 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 0.998 0.771 – 1.29 0.986 62 619 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1.02 0.972 – 1.07 0.436 1907 19117 exclusion phecode
600 Hyperplasia of prostate Genitourinary 1.02 1 – 1.04 0.0447 11093 87892 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 1.02 0.973 – 1.07 0.428 2081 20818 exclusion phecode
601.1 Prostatitis Genitourinary 1.03 0.981 – 1.09 0.214 1563 15644 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.93 0.817 – 1.06 0.274 234 2358 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1.03 0.966 – 1.11 0.338 910 9089 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 1.03 0.79 – 1.34 0.83 59 588 exclusion phecode
601.4 Balanoposthitis Genitourinary 0.912 0.809 – 1.03 0.128 287 2864 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.07 0.947 – 1.2 0.295 303 3019 exclusion phecode
602 Other disorders of prostate Genitourinary 1.01 0.954 – 1.07 0.75 1341 13408 exclusion phecode
603 Other disorders of testis Genitourinary 1.01 0.962 – 1.05 0.798 2150 21512 exclusion phecode
603.1 Hydrocele Genitourinary 0.963 0.91 – 1.02 0.183 1339 13402 exclusion phecode
604 Disorders of penis Genitourinary 1 0.965 – 1.04 0.99 3280 32779 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.993 0.955 – 1.03 0.741 2719 27172 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 1.01 0.891 – 1.14 0.922 278 2800 exclusion phecode
608 Other disorders of male genital organs Genitourinary 1 0.966 – 1.04 0.814 2822 28236 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.971 0.845 – 1.12 0.678 214 2138 exclusion phecode
609.1 Infertility, male Genitourinary 0.99 0.776 – 1.26 0.932 63 638 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.901 0.77 – 1.05 0.19 169 1698 exclusion phecode
610 Benign mammary dysplasias Genitourinary 1.01 0.969 – 1.05 0.625 2464 24658 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.986 0.922 – 1.05 0.677 918 9194 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 0.995 0.884 – 1.12 0.928 302 3046 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 1.05 0.931 – 1.18 0.421 299 3007 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 1.01 0.96 – 1.07 0.598 1381 13778 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.97 0.898 – 1.05 0.438 690 6918 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.07 1.02 – 1.13 0.00969 1566 15625 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.973 0.733 – 1.29 0.851 56 569 exclusion phecode
611.3 Lump or mass in breast Genitourinary 1.08 1.03 – 1.14 0.00305 1515 15108 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.994 0.927 – 1.07 0.861 881 8847 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.999 0.931 – 1.07 0.982 845 8464 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 0.968 0.768 – 1.22 0.786 70 717 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 1.02 0.97 – 1.07 0.431 1640 16430 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.07 0.994 – 1.16 0.0722 715 7165 exclusion phecode
613.5 Mastodynia Genitourinary 0.874 0.69 – 1.11 0.262 76 766 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.985 0.912 – 1.07 0.711 695 6972 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 0.984 0.877 – 1.1 0.789 324 3264 exclusion phecode
613.9 Breast disorder NOS Genitourinary 0.999 0.868 – 1.15 0.988 207 2057 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.03 1.01 – 1.06 0.0171 5533 56832 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.01 0.973 – 1.06 0.501 2436 25241 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.01 0.94 – 1.09 0.783 797 8268 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.971 0.743 – 1.27 0.829 60 605 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.05 0.948 – 1.16 0.355 405 4201 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.991 0.885 – 1.11 0.872 336 3491 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.04 0.92 – 1.18 0.526 273 2760 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.04 1 – 1.09 0.0426 2544 25889 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.08 1.02 – 1.14 0.011 1294 13111 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.02 0.922 – 1.14 0.662 410 4250 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.03 0.954 – 1.11 0.453 752 7539 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.05 0.928 – 1.19 0.438 267 2723 exclusion phecode
615 Endometriosis Genitourinary 1.04 1 – 1.07 0.0286 3923 40099 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.1 0.976 – 1.25 0.115 283 3014 exclusion phecode
618 Genital prolapse Genitourinary 0.993 0.975 – 1.01 0.498 11598 116086 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 1 0.978 – 1.03 0.886 7333 73454 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.977 0.95 – 1.01 0.108 5360 53575 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.942 0.861 – 1.03 0.193 505 5090 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.04 0.962 – 1.13 0.312 669 6748 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 0.993 0.972 – 1.02 0.561 8535 86824 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1 0.928 – 1.09 0.927 686 7246 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 1 0.968 – 1.04 0.844 3277 33083 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.995 0.958 – 1.03 0.816 2824 28467 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1 0.955 – 1.05 0.912 1734 17575 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.974 0.92 – 1.03 0.369 1290 13401 exclusion phecode
621 Endometrial hyperplasia Genitourinary 1.02 0.956 – 1.08 0.592 1116 11228 exclusion phecode
622 Polyp of female genital organs Genitourinary 1.03 1.01 – 1.05 0.0015 10357 104174 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 1.03 1.01 – 1.06 0.0079 7755 78151 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 1.05 1.01 – 1.09 0.00849 3415 34175 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.02 0.961 – 1.08 0.542 1251 12612 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 1.02 0.945 – 1.1 0.653 768 7913 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.949 0.828 – 1.09 0.458 217 2355 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 1.02 0.928 – 1.13 0.629 427 4367 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.979 0.953 – 1.01 0.125 5806 58283 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.04 1 – 1.08 0.0454 2840 28601 exclusion phecode
625.1 Dyspareunia Genitourinary 1.06 0.995 – 1.12 0.0702 1173 11840 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.03 1.01 – 1.04 0.00191 16040 114478 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.03 1.01 – 1.05 0.000894 14009 109411 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.872 0.717 – 1.06 0.172 108 1093 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1.04 1.02 – 1.07 5.35e-05 9656 91339 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 1.01 0.968 – 1.06 0.549 1972 19737 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 1.06 1.02 – 1.09 0.00102 3778 37843 exclusion phecode
626.2 Dysmenorrhea Genitourinary 1.04 0.991 – 1.09 0.109 1769 17689 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.923 0.79 – 1.08 0.309 159 1579 exclusion phecode
626.8 Infertility, female Genitourinary 1.04 0.982 – 1.1 0.187 1354 13563 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 1 0.984 – 1.02 0.684 10268 103317 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 1 0.98 – 1.02 0.876 8929 89885 exclusion phecode
627.2 Symptomatic menopause Genitourinary 1.01 0.865 – 1.18 0.902 181 1819 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.03 0.97 – 1.1 0.314 1096 11046 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1.07 0.954 – 1.21 0.237 308 3082 exclusion phecode
628 Ovarian cyst Genitourinary 1.07 1.04 – 1.1 2.01e-05 4624 47274 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.01 0.98 – 1.04 0.532 5199 36279 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.984 0.927 – 1.05 0.599 1128 11255 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.01 0.902 – 1.12 0.91 330 3283 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.02 0.971 – 1.07 0.46 1968 17310 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.04 0.969 – 1.11 0.282 863 8582 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.02 0.963 – 1.08 0.494 1266 12260 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.02 0.982 – 1.07 0.268 2342 19894 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 1.03 0.946 – 1.12 0.518 617 6117 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.07 1 – 1.14 0.038 1080 10712 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 0.81 0.64 – 1.03 0.0812 68 698 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.961 0.904 – 1.02 0.197 1104 11030 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.886 0.791 – 0.994 0.0384 305 3045 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.902 0.788 – 1.03 0.135 213 2139 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.86 0.732 – 1.01 0.068 152 1518 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.01 0.953 – 1.07 0.739 1246 12404 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.03 0.985 – 1.08 0.196 2219 20766 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.972 0.75 – 1.26 0.833 66 677 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.937 0.828 – 1.06 0.297 272 2743 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.938 0.773 – 1.14 0.515 113 1126 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.01 0.866 – 1.17 0.942 193 1912 exclusion phecode
650 Normal delivery Pregnancy Complications 0.986 0.942 – 1.03 0.567 1919 18898 exclusion phecode
651 Multiple gestation Pregnancy Complications 0.931 0.836 – 1.04 0.192 345 3446 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1.01 0.961 – 1.06 0.694 1710 16462 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.981 0.929 – 1.04 0.506 1398 13601 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.19 0.923 – 1.53 0.182 74 734 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.03 0.998 – 1.06 0.0699 4298 29329 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.883 0.726 – 1.07 0.211 109 1077 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 1.01 0.962 – 1.05 0.809 2259 18327 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.964 0.882 – 1.05 0.415 529 5292 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 1.02 0.988 – 1.05 0.23 5298 29352 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.03 0.986 – 1.07 0.195 2545 21091 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.05 0.896 – 1.23 0.547 164 1622 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.08 0.949 – 1.23 0.24 262 2590 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.827 0.646 – 1.06 0.129 63 623 exclusion phecode
679 Complications of in utero procedures Dermatologic 0.985 0.742 – 1.31 0.919 53 528 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 0.992 0.968 – 1.02 0.524 7144 72042 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.01 0.926 – 1.1 0.817 559 5634 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.01 0.92 – 1.1 0.889 516 5195 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.993 0.966 – 1.02 0.611 5451 54878 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.995 0.968 – 1.02 0.714 5457 54938 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.992 0.965 – 1.02 0.597 5414 54509 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.01 0.93 – 1.1 0.773 579 5966 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.01 0.953 – 1.07 0.779 1328 13389 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 0.973 0.932 – 1.02 0.206 2277 22852 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.04 0.953 – 1.13 0.382 582 5821 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.04 0.929 – 1.16 0.511 360 3601 exclusion phecode
687 Symptoms affecting skin Dermatologic 1.06 0.972 – 1.16 0.182 544 5485 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.01 0.966 – 1.06 0.65 2118 21392 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.12 0.989 – 1.27 0.0743 281 2825 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.927 0.764 – 1.12 0.439 106 1067 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 0.988 0.951 – 1.03 0.545 2871 28778 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.01 0.98 – 1.03 0.603 5716 57297 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 1.12 0.878 – 1.43 0.362 71 710 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 1.07 0.808 – 1.41 0.652 53 530 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.887 0.739 – 1.06 0.195 120 1198 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.983 0.921 – 1.05 0.608 981 9804 exclusion phecode
694.1 Vitiligo Dermatologic 1.05 0.794 – 1.38 0.743 59 599 exclusion phecode
694.2 Other dyschromia Dermatologic 0.971 0.903 – 1.04 0.429 780 7782 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 0.949 0.789 – 1.14 0.58 115 1166 exclusion phecode
695 Erythematous conditions Dermatologic 1.03 0.983 – 1.07 0.232 2352 23702 exclusion phecode
695.1 Toxic erythema Dermatologic 0.939 0.772 – 1.14 0.533 108 1085 exclusion phecode
695.2 Bullous dermatoses Dermatologic 0.942 0.797 – 1.11 0.486 136 1363 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 0.931 0.727 – 1.19 0.568 57 567 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.996 0.788 – 1.26 0.975 72 727 exclusion phecode
695.3 Rosacea Dermatologic 1.1 0.977 – 1.25 0.112 308 3083 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.03 0.932 – 1.15 0.531 409 4087 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.934 0.78 – 1.12 0.462 130 1288 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.02 0.915 – 1.15 0.674 338 3389 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 1.04 0.965 – 1.12 0.308 765 7721 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 0.928 0.814 – 1.06 0.265 233 2349 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.815 0.645 – 1.03 0.0864 76 758 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.03 0.932 – 1.13 0.584 457 4658 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.996 0.954 – 1.04 0.847 2245 22442 exclusion phecode
696.4 Psoriasis Dermatologic 0.991 0.949 – 1.03 0.679 2191 21903 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.99 0.942 – 1.04 0.684 1673 16748 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 1.01 0.935 – 1.09 0.81 706 7027 exclusion phecode
697 Sarcoidosis Dermatologic 1.02 0.934 – 1.11 0.658 534 5353 exclusion phecode
698 Pruritus and related conditions Dermatologic 0.973 0.903 – 1.05 0.481 773 7793 exclusion phecode
700 Corns and callosities Dermatologic 1.03 0.917 – 1.16 0.592 288 2885 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.01 0.976 – 1.04 0.688 4635 46461 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 1.09 0.868 – 1.37 0.457 86 869 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.01 0.964 – 1.05 0.784 2333 23376 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 1.05 0.811 – 1.35 0.727 60 607 exclusion phecode
701.4 Keloid scar Dermatologic 0.977 0.848 – 1.13 0.744 216 2150 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1.03 0.929 – 1.13 0.615 452 4547 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.25 1.01 – 1.55 0.0388 101 1017 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.974 0.947 – 1 0.0646 5408 54373 exclusion phecode
702.1 Actinic keratosis Dermatologic 1 0.963 – 1.04 0.888 2550 25737 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.943 0.909 – 0.978 0.00179 3061 30653 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.01 0.905 – 1.12 0.885 354 3527 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.997 0.933 – 1.06 0.919 960 9626 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.978 0.951 – 1.01 0.12 5250 52562 exclusion phecode
704.1 Alopecia Dermatologic 0.993 0.83 – 1.19 0.935 123 1263 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.813 0.644 – 1.03 0.0828 76 757 exclusion phecode
705 Disorders of sweat glands Dermatologic 0.883 0.77 – 1.01 0.0752 226 2278 exclusion phecode
705.3 Hidradenitis Dermatologic 0.918 0.79 – 1.07 0.267 185 1860 exclusion phecode
705.8 Hyperhidrosis Dermatologic 0.958 0.881 – 1.04 0.324 588 5905 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 0.989 0.967 – 1.01 0.349 8286 82894 exclusion phecode
706.1 Acne Dermatologic 0.832 0.662 – 1.05 0.115 78 776 exclusion phecode
706.2 Sebaceous cyst Dermatologic 0.992 0.97 – 1.01 0.455 8752 87572 exclusion phecode
707 Chronic ulcer of skin Dermatologic 0.992 0.947 – 1.04 0.742 1937 19600 exclusion phecode
707.1 Decubitus ulcer Dermatologic 0.983 0.919 – 1.05 0.621 901 9065 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.971 0.938 – 1.01 0.099 3414 34162 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.02 0.934 – 1.12 0.625 503 5045 exclusion phecode
709.3 Systemic sclerosis Dermatologic 1.11 0.945 – 1.3 0.204 176 1745 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.05 0.811 – 1.35 0.727 64 647 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.957 0.92 – 0.995 0.0266 2702 27034 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.961 0.885 – 1.05 0.356 602 6021 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 0.972 0.891 – 1.06 0.527 556 5563 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.988 0.855 – 1.14 0.872 194 1943 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.966 0.871 – 1.07 0.505 398 3986 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 1.02 0.918 – 1.12 0.756 418 4219 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 0.963 0.861 – 1.08 0.514 326 3291 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 0.815 0.644 – 1.03 0.0879 80 809 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.963 0.821 – 1.13 0.643 148 1495 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 0.972 0.762 – 1.24 0.817 65 668 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.999 0.969 – 1.03 0.927 4792 48087 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.01 0.978 – 1.04 0.592 4337 43505 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.999 0.95 – 1.05 0.977 1652 16528 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.972 0.799 – 1.18 0.773 113 1122 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.02 0.938 – 1.11 0.666 617 6163 exclusion phecode
716 Other arthropathies Musculoskeletal 1 0.991 – 1.01 0.786 37285 264481 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1 0.966 – 1.04 0.984 3487 34930 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.01 0.994 – 1.03 0.231 15475 154827 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1 0.991 – 1.01 0.699 35757 261420 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.02 0.962 – 1.09 0.476 1133 11425 exclusion phecode
720 Spinal stenosis Musculoskeletal 0.969 0.937 – 1 0.0628 3690 36943 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 0.987 0.964 – 1.01 0.259 7776 78011 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.986 0.958 – 1.01 0.338 5010 50255 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.04 0.9 – 1.21 0.573 188 1896 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 0.863 0.774 – 0.961 0.00726 350 3504 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 0.992 0.971 – 1.01 0.491 8943 89534 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.984 0.898 – 1.08 0.736 510 5101 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.02 0.977 – 1.06 0.441 2820 28204 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 0.98 0.781 – 1.23 0.858 67 662 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.997 0.966 – 1.03 0.833 4391 43976 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 0.996 0.91 – 1.09 0.927 516 5161 exclusion phecode
723.1 Torticollis Musculoskeletal 0.892 0.743 – 1.07 0.223 107 1065 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1 0.956 – 1.05 0.998 2042 20438 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 0.983 0.888 – 1.09 0.732 400 4002 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.973 0.88 – 1.08 0.59 403 4031 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.06 0.821 – 1.38 0.637 62 629 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.01 0.958 – 1.06 0.763 1608 16088 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1 0.984 – 1.02 0.893 14616 146170 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.999 0.978 – 1.02 0.944 9557 95565 exclusion phecode
726.2 Synoviopathy Musculoskeletal 1.03 0.921 – 1.15 0.608 333 3318 exclusion phecode
726.3 Bursitis Musculoskeletal 1.02 0.952 – 1.1 0.541 851 8557 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1 0.979 – 1.03 0.823 7299 73038 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1 0.965 – 1.04 0.867 2727 27296 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.925 0.766 – 1.12 0.417 103 1022 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.02 0.985 – 1.06 0.248 3090 30947 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.984 0.903 – 1.07 0.706 583 5838 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.974 0.874 – 1.09 0.642 353 3508 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.01 0.851 – 1.19 0.935 143 1427 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.982 0.949 – 1.02 0.292 3671 36720 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.04 0.942 – 1.16 0.406 411 4101 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.988 0.956 – 1.02 0.473 3796 37974 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.983 0.949 – 1.02 0.324 3471 34724 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.01 0.986 – 1.04 0.345 5964 60082 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.99 0.927 – 1.06 0.76 996 10006 exclusion phecode
729.3 Panniculitis Musculoskeletal 1.08 0.882 – 1.33 0.44 101 1008 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.956 0.843 – 1.09 0.488 268 2744 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.951 0.835 – 1.08 0.45 253 2594 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.948 0.863 – 1.04 0.266 465 4663 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.966 0.84 – 1.11 0.623 206 2058 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.937 0.726 – 1.21 0.617 57 569 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.966 0.92 – 1.01 0.16 1766 17731 exclusion phecode
733.2 Cyst of bone Musculoskeletal 0.926 0.827 – 1.04 0.188 311 3101 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.01 0.927 – 1.11 0.766 538 5378 exclusion phecode
733.6 Costochondritis Musculoskeletal 0.951 0.797 – 1.13 0.572 128 1272 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.98 0.926 – 1.04 0.502 1223 12276 exclusion phecode
733.9 Chondromalacia Musculoskeletal 0.963 0.794 – 1.17 0.701 121 1203 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1.01 0.99 – 1.03 0.289 9550 95543 exclusion phecode
735.1 Flat foot Musculoskeletal 0.949 0.823 – 1.09 0.473 188 1899 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 1.03 0.996 – 1.06 0.095 5041 50421 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.03 0.983 – 1.08 0.21 1916 19213 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 1.02 0.968 – 1.08 0.45 1547 15448 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.01 0.982 – 1.03 0.582 6604 66049 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 0.979 0.93 – 1.03 0.408 1619 16225 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.01 0.881 – 1.15 0.92 247 2468 exclusion phecode
737 Curvature of spine Musculoskeletal 0.962 0.905 – 1.02 0.213 1119 11237 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.954 0.896 – 1.02 0.141 1055 10567 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.02 0.971 – 1.07 0.47 1894 18967 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.01 0.959 – 1.07 0.696 1504 15072 exclusion phecode
739 Contracture of joint Musculoskeletal 0.941 0.859 – 1.03 0.191 483 4869 exclusion phecode
740 Osteoarthrosis Musculoskeletal 0.992 0.98 – 1 0.205 27569 230737 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.989 0.974 – 1.01 0.184 17345 168730 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.985 0.964 – 1.01 0.168 8941 89391 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.995 0.891 – 1.11 0.929 346 3463 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.04 0.96 – 1.14 0.311 592 5944 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.996 0.978 – 1.01 0.684 12185 122272 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.03 0.991 – 1.06 0.151 3553 35540 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 1.05 0.857 – 1.29 0.624 102 1017 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 0.988 0.91 – 1.07 0.782 612 6119 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.972 0.823 – 1.15 0.742 153 1533 exclusion phecode
741.4 Joint effusions Musculoskeletal 1.05 0.992 – 1.11 0.0953 1414 14153 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1 0.829 – 1.21 0.993 110 1098 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 1.23 0.926 – 1.63 0.152 54 532 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.958 0.922 – 0.995 0.0279 2838 28356 exclusion phecode
742.1 Loose body in joint Musculoskeletal 0.907 0.814 – 1.01 0.0773 333 3329 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.02 0.836 – 1.26 0.813 95 955 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 0.917 0.837 – 1 0.0596 498 4980 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.977 0.932 – 1.02 0.317 1990 19863 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1 0.979 – 1.03 0.849 7493 75281 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1 0.979 – 1.03 0.718 6339 63707 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1 0.972 – 1.03 0.987 5494 55231 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 0.992 0.908 – 1.08 0.859 523 5264 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 0.938 0.858 – 1.03 0.162 508 5155 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.02 0.947 – 1.09 0.635 812 8107 exclusion phecode
745 Pain in joint Musculoskeletal 1.02 0.996 – 1.04 0.102 7941 79486 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.02 0.978 – 1.06 0.412 2789 27975 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.01 0.971 – 1.05 0.608 2618 26247 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.997 0.915 – 1.09 0.947 583 5815 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.02 0.895 – 1.17 0.732 234 2352 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1 0.956 – 1.05 0.895 1810 18150 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.07 0.908 – 1.25 0.428 164 1677 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.05 0.789 – 1.39 0.745 51 507 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.885 0.789 – 0.993 0.0374 303 3015 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 1.04 0.957 – 1.12 0.374 681 6850 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.03 0.92 – 1.16 0.595 325 3256 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.99 0.854 – 1.15 0.897 189 1906 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.06 0.949 – 1.18 0.303 353 3556 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.998 0.868 – 1.15 0.975 223 2248 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.22 1 – 1.48 0.0445 116 1172 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.979 0.93 – 1.03 0.434 1520 15243 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.988 0.915 – 1.07 0.758 691 6911 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.995 0.906 – 1.09 0.922 452 4525 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.02 0.885 – 1.17 0.805 222 2217 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.989 0.921 – 1.06 0.764 832 8365 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 1.03 0.932 – 1.14 0.554 421 4233 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.936 0.838 – 1.05 0.243 332 3339 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.987 0.879 – 1.11 0.821 327 3295 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 0.994 0.873 – 1.13 0.931 252 2547 exclusion phecode
752.11 Spina bifida Congenital Anomalies 1.03 0.894 – 1.19 0.66 207 2098 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.95 0.758 – 1.19 0.659 78 777 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.923 0.771 – 1.1 0.381 127 1267 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1 0.8 – 1.26 0.981 76 759 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.979 0.807 – 1.19 0.833 108 1096 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.997 0.901 – 1.1 0.958 423 4255 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.969 0.837 – 1.12 0.68 207 2078 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.919 0.779 – 1.08 0.318 160 1614 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.934 0.764 – 1.14 0.509 106 1064 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.997 0.915 – 1.09 0.942 584 5856 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.19 0.942 – 1.51 0.143 81 807 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.944 0.856 – 1.04 0.254 432 4339 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.13 0.952 – 1.33 0.164 147 1702 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.21 0.934 – 1.56 0.149 60 825 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.07 0.928 – 1.24 0.343 212 2153 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.15 0.927 – 1.43 0.204 96 955 exclusion phecode
760 Back pain Symptoms 1.01 0.99 – 1.03 0.365 11067 110933 exclusion phecode
761 Cervicalgia Symptoms 1.02 0.967 – 1.07 0.529 1779 17834 exclusion phecode
764 Sciatica Symptoms 1.01 0.965 – 1.05 0.764 2365 23646 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.973 0.917 – 1.03 0.372 1168 11685 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 0.981 0.906 – 1.06 0.644 628 6295 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.03 0.957 – 1.1 0.472 865 8662 exclusion phecode
771.1 Swelling of limb Symptoms 1.02 0.987 – 1.05 0.256 4576 46170 exclusion phecode
772 Symptoms of the muscles Symptoms 1.1 1.01 – 1.19 0.0269 654 6558 exclusion phecode
773 Pain in limb Symptoms 0.999 0.973 – 1.03 0.927 6177 61969 exclusion phecode
780 Hypothermia/Chills Symptoms 0.892 0.761 – 1.05 0.157 171 1714 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.998 0.952 – 1.05 0.946 1862 18658 exclusion phecode
782.3 Edema Symptoms 1.01 0.962 – 1.07 0.634 1614 16395 exclusion phecode
782.6 Pallor and flushing Symptoms 1.03 0.883 – 1.19 0.741 174 1743 exclusion phecode
783 Fever of unknown origin Symptoms 1.03 0.993 – 1.06 0.117 3826 38989 exclusion phecode
785 Abdominal pain Symptoms 1 0.994 – 1.01 0.431 39766 300783 exclusion phecode
788 Syncope and collapse Symptoms 1.01 0.99 – 1.03 0.309 9025 90554 exclusion phecode
789 Nausea and vomiting Symptoms 1 0.986 – 1.02 0.617 11364 115403 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.01 0.859 – 1.2 0.862 150 1497 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.11 0.888 – 1.37 0.37 84 835 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.02 0.994 – 1.05 0.138 6309 63539 exclusion phecode
791 Gangrene Symptoms 1.02 0.93 – 1.11 0.738 545 5487 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1.07 0.861 – 1.33 0.536 95 966 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.963 0.807 – 1.15 0.68 131 1338 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 0.968 0.887 – 1.06 0.461 560 5624 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.962 0.793 – 1.17 0.692 119 1191 exclusion phecode
797 Shock Symptoms 0.915 0.781 – 1.07 0.272 156 1557 exclusion phecode
797.1 Cardiogenic shock Symptoms 0.832 0.684 – 1.01 0.0665 102 1019 exclusion phecode
798 Malaise and fatigue Symptoms 1.02 0.98 – 1.05 0.404 3364 33981 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 0.944 0.868 – 1.03 0.177 588 5885 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 0.992 0.968 – 1.02 0.5 6995 70053 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.974 0.928 – 1.02 0.292 1798 18070 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.88 0.753 – 1.03 0.105 169 1686 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.01 0.962 – 1.05 0.813 2146 21523 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.953 0.885 – 1.02 0.193 766 7632 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.01 0.971 – 1.06 0.51 2192 21961 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.01 0.961 – 1.06 0.756 1825 18283 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 0.961 0.891 – 1.04 0.308 715 7164 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.998 0.976 – 1.02 0.85 8250 82520 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 0.992 0.943 – 1.04 0.749 1685 16802 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.998 0.97 – 1.03 0.872 5188 51898 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.01 0.953 – 1.06 0.854 1512 15168 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.992 0.958 – 1.03 0.669 3328 33295 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.01 0.956 – 1.07 0.699 1352 13524 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.01 0.941 – 1.09 0.735 772 7730 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.03 0.974 – 1.09 0.291 1295 12958 exclusion phecode
817 Concussion Injuries & Poisonings 1.02 0.898 – 1.16 0.749 243 2420 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.01 0.925 – 1.11 0.797 519 5206 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.05 1.01 – 1.09 0.0126 2947 29545 exclusion phecode
823 Torus fracture Injuries & Poisonings 0.993 0.944 – 1.04 0.77 1663 16662 exclusion phecode
830 Dislocation Injuries & Poisonings 0.981 0.938 – 1.03 0.416 2081 20831 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.999 0.983 – 1.02 0.932 15185 151825 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.999 0.914 – 1.09 0.982 525 5260 exclusion phecode
840 Sprains and strains Injuries & Poisonings 1.01 0.916 – 1.11 0.899 469 4684 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.02 0.989 – 1.05 0.241 5196 52463 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.08 0.908 – 1.27 0.398 156 1559 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.03 0.936 – 1.13 0.551 480 5001 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.02 0.97 – 1.07 0.472 1814 18201 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.02 0.964 – 1.08 0.479 1230 12379 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.982 0.947 – 1.02 0.34 3141 31484 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 0.999 0.964 – 1.04 0.971 3235 32498 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.39 1.08 – 1.8 0.0119 67 679 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.04 1 – 1.07 0.0387 3495 34973 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.924 0.816 – 1.05 0.213 272 2710 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1.08 0.928 – 1.25 0.331 196 1946 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.02 0.985 – 1.06 0.226 2897 29014 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.11 0.968 – 1.28 0.133 219 2193 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.925 0.725 – 1.18 0.533 68 678 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 0.996 0.964 – 1.03 0.82 4050 40552 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.987 0.742 – 1.31 0.928 53 530 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.03 0.832 – 1.26 0.814 90 898 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.958 0.823 – 1.11 0.576 178 1781 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 0.98 0.892 – 1.08 0.68 475 4738 exclusion phecode
873 Broken tooth Injuries & Poisonings 1.06 0.932 – 1.21 0.359 228 2284 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.12 0.956 – 1.32 0.16 169 1705 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 0.921 0.786 – 1.08 0.308 157 1562 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 0.954 0.902 – 1.01 0.0989 1310 13105 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.01 0.975 – 1.04 0.726 4238 42543 exclusion phecode
916 Contusion Injuries & Poisonings 1.03 0.977 – 1.09 0.262 1445 14472 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.984 0.843 – 1.15 0.836 178 1797 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.97 0.873 – 1.08 0.563 387 3885 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.967 0.85 – 1.1 0.609 252 2518 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1 0.96 – 1.05 0.869 2077 20896 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.16 1.01 – 1.34 0.0381 221 2241 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.878 0.721 – 1.07 0.194 100 1033 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.07 0.981 – 1.17 0.126 548 5488 exclusion phecode
947 Urticaria Injuries & Poisonings 0.982 0.881 – 1.09 0.736 369 3694 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.13 1.02 – 1.26 0.0201 393 3978 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.08 0.973 – 1.19 0.155 421 4211 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.905 0.799 – 1.02 0.114 268 2685 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.973 0.889 – 1.07 0.562 487 4923 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.02 0.781 – 1.35 0.86 52 554 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.862 0.687 – 1.08 0.199 73 738 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.01 0.995 – 1.03 0.174 17935 180432 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.01 0.997 – 1.03 0.112 15713 158012 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.03 0.93 – 1.14 0.592 410 4174 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.01 0.94 – 1.08 0.823 861 8664 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.08 0.973 – 1.2 0.147 367 3695 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.09 0.979 – 1.21 0.115 360 3626 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.996 0.867 – 1.14 0.96 215 2218 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.05 0.931 – 1.19 0.414 279 2823 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.04 0.92 – 1.18 0.518 273 2763 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1 0.976 – 1.03 0.844 6026 60632 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.01 0.953 – 1.08 0.666 1125 11397 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.03 0.941 – 1.14 0.485 475 4751 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.918 0.831 – 1.01 0.0887 403 4035 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.01 0.926 – 1.11 0.781 510 5099 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.977 0.898 – 1.06 0.588 575 5817 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.05 1 – 1.1 0.0346 1939 19457 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.998 0.861 – 1.16 0.983 188 1904 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.1 0.97 – 1.25 0.135 270 2708 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.989 0.797 – 1.23 0.922 84 846 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.07 0.879 – 1.31 0.488 108 1074 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.21 0.98 – 1.49 0.0761 101 1012 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.1 0.849 – 1.43 0.467 64 640 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.817 0.635 – 1.05 0.117 58 578 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.19 1.03 – 1.36 0.0156 226 2332 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.11 1.03 – 1.2 0.0094 687 6944 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.989 0.855 – 1.14 0.885 200 1992 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.04 0.792 – 1.36 0.784 62 620 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.02 0.839 – 1.25 0.817 104 1047 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 1.08 0.889 – 1.31 0.438 111 1123 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.05 0.84 – 1.31 0.663 89 887 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 0.986 0.95 – 1.02 0.46 3045 31026 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.01 0.974 – 1.05 0.568 2958 30182 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.01 0.974 – 1.05 0.568 2958 30182 exclusion phecode
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