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Scores Malignant neoplasm of ovary UK Biobank (UKB) PheWAS analysis

Malignant neoplasm of ovary — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID prsweb-phecode184-11-phelan-lsasboc-pt-ukb-20200608Legacy P&TP&TPhelan CM et al. 2017

Evaluation cohort: UK Biobank (UKB).

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121 rows visible 16 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 0.996 0.974 – 1.02 0.69 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 0.988 0.949 – 1.03 0.542 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.969 0.894 – 1.05 0.442 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 1.02 0.948 – 1.09 0.637 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.44 1.1 – 1.9 0.00878 55 550 all phecode
010 Tuberculosis Infectious Diseases 0.905 0.774 – 1.06 0.215 166 1659 all phecode
038 Septicemia Infectious Diseases 1.02 0.991 – 1.06 0.169 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.05 0.98 – 1.13 0.159 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.01 0.917 – 1.1 0.902 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 1 0.984 – 1.02 0.752 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.01 0.972 – 1.05 0.667 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 0.986 0.937 – 1.04 0.574 1641 16433 all phecode
041.4 E. coli Infectious Diseases 1.02 0.978 – 1.06 0.397 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 1.06 0.959 – 1.18 0.246 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.21 0.977 – 1.49 0.0815 95 949 all phecode
054 Herpes simplex Infectious Diseases 1.12 0.975 – 1.29 0.111 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 0.976 0.899 – 1.06 0.569 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 0.916 0.708 – 1.19 0.506 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.02 0.854 – 1.22 0.825 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 0.978 0.864 – 1.11 0.727 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.1 0.965 – 1.24 0.158 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 0.919 0.831 – 1.02 0.1 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.84 0.714 – 0.989 0.036 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.808 0.675 – 0.966 0.0195 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 1.02 0.956 – 1.09 0.557 1004 10036 all phecode
079 Viral infection Infectious Diseases 1.02 0.981 – 1.06 0.318 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 1.16 0.901 – 1.48 0.256 64 640 all phecode
080 Postoperative infection Infectious Diseases 1.03 0.997 – 1.06 0.0763 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.04 0.994 – 1.08 0.0967 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.977 0.771 – 1.24 0.85 71 709 all phecode
1000 Burns Injuries & Poisonings 1.03 0.948 – 1.13 0.455 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 0.974 0.918 – 1.03 0.373 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.02 0.988 – 1.04 0.274 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 0.959 0.852 – 1.08 0.496 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 0.963 0.913 – 1.02 0.17 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 0.925 0.813 – 1.05 0.232 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 0.99 0.87 – 1.13 0.876 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 0.997 0.935 – 1.06 0.927 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 1.01 0.988 – 1.03 0.353 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 0.991 0.965 – 1.02 0.494 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.987 0.966 – 1.01 0.233 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 1.04 0.844 – 1.27 0.737 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.01 0.903 – 1.13 0.855 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.09 0.853 – 1.4 0.481 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 1.02 0.984 – 1.05 0.343 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1 0.986 – 1.02 0.81 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.03 0.908 – 1.17 0.658 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 1.02 0.898 – 1.16 0.77 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.874 0.688 – 1.11 0.271 74 756 all phecode
110.12 Althete's foot Infectious Diseases 1.04 0.877 – 1.24 0.638 141 1410 all phecode
112 Candidiasis Infectious Diseases 0.986 0.943 – 1.03 0.538 2126 21275 all phecode
117 Mycoses Infectious Diseases 1.02 0.897 – 1.15 0.801 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 0.993 0.848 – 1.16 0.933 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 0.92 0.735 – 1.15 0.47 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 0.791 0.625 – 1 0.051 69 689 all phecode
134 Helminthiases Infectious Diseases 1 0.835 – 1.2 0.978 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.04 0.846 – 1.27 0.73 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.02 0.884 – 1.18 0.796 205 2050 all phecode
145 Cancer of mouth Neoplasms 0.969 0.894 – 1.05 0.453 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 1.03 0.917 – 1.16 0.615 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.17 0.958 – 1.44 0.123 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 0.869 0.675 – 1.12 0.278 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.972 0.896 – 1.05 0.482 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 0.921 0.812 – 1.04 0.2 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 1.02 0.9 – 1.16 0.756 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 1.1 0.836 – 1.45 0.495 57 570 all phecode
150 Cancer of esophagus Neoplasms 1.04 0.965 – 1.12 0.309 762 7630 all phecode
151 Cancer of stomach Neoplasms 1.01 0.926 – 1.1 0.858 569 5696 all phecode
153 Colorectal cancer Neoplasms 0.986 0.957 – 1.02 0.373 4580 45799 all phecode
153.2 Colon cancer Neoplasms 0.982 0.947 – 1.02 0.337 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.996 0.953 – 1.04 0.841 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.856 0.773 – 0.948 0.00277 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.835 0.706 – 0.987 0.0348 158 1580 all phecode
157 Pancreatic cancer Neoplasms 0.966 0.893 – 1.05 0.396 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.01 0.95 – 1.08 0.73 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1 0.974 – 1.03 0.937 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1 0.863 – 1.17 0.955 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.9 0.785 – 1.03 0.131 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.25 1.08 – 1.45 0.00325 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 0.881 0.683 – 1.14 0.329 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 1.05 1.01 – 1.09 0.014 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.04 1 – 1.09 0.051 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 1.05 0.949 – 1.15 0.368 437 4364 all phecode
170.1 Bone cancer Neoplasms 1.07 0.901 – 1.28 0.423 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 1.04 0.933 – 1.17 0.454 331 3303 all phecode
172 Skin cancer Neoplasms 1.02 1.01 – 1.04 0.0106 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.07 1.03 – 1.11 0.00101 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 1.07 1.03 – 1.12 0.000457 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1.02 1 – 1.04 0.0423 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 0.925 0.854 – 1 0.0578 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.15 0.99 – 1.34 0.0677 181 1818 all phecode
174 Breast cancer Neoplasms 1.03 1.01 – 1.04 0.0068 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 1.03 1.01 – 1.05 0.00457 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.02 1 – 1.04 0.0136 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.08 0.897 – 1.31 0.408 115 1148 all phecode
175 Acquired absence of breast Neoplasms 1.06 1.02 – 1.11 0.0043 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 1.02 0.976 – 1.07 0.362 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 1.01 0.886 – 1.14 0.917 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.02 0.979 – 1.07 0.301 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 1.06 1 – 1.13 0.0377 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 1.18 1.11 – 1.24 3.25e-08 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.19 1.11 – 1.28 5.35e-07 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.18 1.1 – 1.26 4.9e-06 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.07 0.945 – 1.21 0.293 305 3049 all phecode
185 Cancer of prostate Neoplasms 0.961 0.936 – 0.986 0.00291 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 0.889 0.81 – 0.977 0.0142 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.852 0.679 – 1.07 0.169 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.909 0.81 – 1.02 0.103 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.03 0.849 – 1.25 0.76 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.03 1 – 1.07 0.0425 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.04 0.978 – 1.11 0.205 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.03 0.962 – 1.09 0.434 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.22 0.961 – 1.55 0.103 66 660 all phecode
189.2 Cancer of bladder Neoplasms 1.03 0.984 – 1.07 0.224 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.03 0.981 – 1.07 0.261 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.03 0.867 – 1.22 0.744 144 1439 all phecode
190 Cancer of eye Neoplasms 1.13 0.966 – 1.32 0.126 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.19 1.1 – 1.29 1.88e-05 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1.2 1.1 – 1.31 4.61e-05 566 5650 all phecode
191.11 Cancer of brain Neoplasms 1.2 1.1 – 1.31 6.3e-05 525 5240 all phecode
193 Thyroid cancer Neoplasms 1.08 0.962 – 1.21 0.196 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 1.19 0.959 – 1.47 0.115 95 949 all phecode
195 Cancer, suspected or other Neoplasms 1 0.988 – 1.02 0.6 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.01 0.991 – 1.02 0.401 16267 159497 all phecode
197 Chemotherapy Neoplasms 1.01 0.995 – 1.02 0.216 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 1.01 0.99 – 1.03 0.328 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1 0.973 – 1.03 0.945 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1 0.961 – 1.05 0.869 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1 0.951 – 1.06 0.921 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.01 0.975 – 1.06 0.47 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.02 0.955 – 1.1 0.497 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 0.999 0.956 – 1.04 0.973 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.04 0.895 – 1.21 0.594 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.01 0.958 – 1.07 0.67 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 0.986 0.802 – 1.21 0.893 95 950 all phecode
200 Myeloproliferative disease Neoplasms 1.2 1.12 – 1.28 4.64e-08 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 1.23 1.11 – 1.37 9.9e-05 387 3867 all phecode
201 Hodgkin's disease Neoplasms 0.928 0.817 – 1.05 0.248 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.02 0.977 – 1.06 0.372 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.02 0.969 – 1.07 0.483 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 1.07 0.96 – 1.19 0.223 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 0.989 0.908 – 1.08 0.807 581 5824 all phecode
204 Leukemia Neoplasms 1.04 0.99 – 1.1 0.113 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 0.996 0.914 – 1.08 0.92 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.09 0.83 – 1.43 0.534 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.988 0.902 – 1.08 0.785 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 1.11 1.01 – 1.22 0.0244 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 1.14 1.02 – 1.27 0.0255 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.984 0.832 – 1.16 0.855 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 1.06 0.97 – 1.16 0.2 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 0.993 0.979 – 1.01 0.375 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.989 0.926 – 1.06 0.731 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.01 0.977 – 1.03 0.726 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.92 0.825 – 1.03 0.135 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.933 0.833 – 1.04 0.231 318 3187 all phecode
214 Lipoma Neoplasms 1.03 1.01 – 1.06 0.0145 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.04 1.01 – 1.07 0.0176 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.08 1.01 – 1.14 0.0209 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 1.02 1 – 1.05 0.0469 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.966 0.89 – 1.05 0.408 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 0.978 0.899 – 1.06 0.607 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 1.08 1.05 – 1.1 5.9e-12 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 1.08 1.06 – 1.1 3.95e-13 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.11 0.993 – 1.24 0.0671 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 1.09 1.03 – 1.15 0.00205 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.11 0.964 – 1.28 0.145 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.942 0.802 – 1.11 0.463 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.08 0.922 – 1.26 0.342 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 0.935 0.783 – 1.12 0.457 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.804 0.631 – 1.02 0.0767 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.14 1.06 – 1.22 0.000559 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.14 1.06 – 1.23 0.000587 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.04 0.794 – 1.35 0.795 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.09 0.961 – 1.24 0.177 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.996 0.929 – 1.07 0.912 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.954 0.822 – 1.11 0.533 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.993 0.893 – 1.1 0.899 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.01 0.901 – 1.14 0.83 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.08 1.02 – 1.13 0.005 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.04 1 – 1.09 0.0496 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.02 0.934 – 1.11 0.688 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.04 0.976 – 1.1 0.23 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.01 0.921 – 1.11 0.801 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.05 0.972 – 1.14 0.211 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.02 0.975 – 1.07 0.353 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 1.08 0.979 – 1.19 0.122 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 0.69 0.557 – 0.854 0.000657 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.11 0.935 – 1.33 0.225 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 1.01 0.994 – 1.03 0.207 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.04 0.976 – 1.11 0.227 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.906 0.741 – 1.11 0.335 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.01 0.994 – 1.03 0.201 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 1.01 0.892 – 1.14 0.921 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.14 0.987 – 1.31 0.0747 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.14 0.985 – 1.32 0.0787 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.06 0.95 – 1.17 0.312 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 1 0.99 – 1.02 0.522 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1 0.961 – 1.04 0.988 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.07 0.934 – 1.22 0.334 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.13 0.897 – 1.43 0.294 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.02 0.931 – 1.12 0.643 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.12 0.958 – 1.31 0.154 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1 0.986 – 1.02 0.903 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.974 0.8 – 1.19 0.793 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.06 0.914 – 1.22 0.461 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.06 0.989 – 1.13 0.103 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.03 0.945 – 1.13 0.468 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 0.958 0.885 – 1.04 0.286 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.914 0.806 – 1.04 0.163 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.997 0.901 – 1.1 0.951 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.03 0.859 – 1.23 0.771 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.06 0.958 – 1.18 0.245 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.05 0.994 – 1.11 0.0795 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 0.999 0.934 – 1.07 0.975 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.985 0.917 – 1.06 0.67 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.993 0.921 – 1.07 0.855 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.816 0.685 – 0.973 0.0234 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.99 0.915 – 1.07 0.795 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.993 0.857 – 1.15 0.923 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.978 0.793 – 1.21 0.836 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.958 0.844 – 1.09 0.503 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.02 0.831 – 1.26 0.837 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.03 0.879 – 1.21 0.706 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.05 0.965 – 1.13 0.275 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.989 0.849 – 1.15 0.888 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.02 0.839 – 1.25 0.821 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.963 0.762 – 1.22 0.756 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.05 0.943 – 1.17 0.375 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.06 0.949 – 1.18 0.317 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.04 0.911 – 1.19 0.562 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.04 0.901 – 1.2 0.594 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 0.96 0.818 – 1.13 0.618 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.967 0.821 – 1.14 0.69 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.09 0.892 – 1.34 0.393 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.14 0.967 – 1.34 0.12 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.07 0.933 – 1.24 0.318 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 0.787 0.595 – 1.04 0.0953 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 0.978 0.911 – 1.05 0.546 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.02 0.962 – 1.08 0.5 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1 0.931 – 1.08 0.949 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.02 0.925 – 1.13 0.673 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.859 0.684 – 1.08 0.191 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.907 0.795 – 1.03 0.143 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 1.1 0.983 – 1.23 0.0961 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.24 1.1 – 1.4 0.000391 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.21 1.07 – 1.38 0.00353 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.2 1.03 – 1.39 0.0211 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 0.913 0.76 – 1.1 0.329 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.27 1 – 1.62 0.0476 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.1 0.932 – 1.29 0.267 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.13 0.947 – 1.34 0.176 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.994 0.983 – 1.01 0.286 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.994 0.982 – 1 0.261 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.993 0.981 – 1 0.209 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.843 0.645 – 1.1 0.212 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.07 0.915 – 1.26 0.378 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.975 0.848 – 1.12 0.724 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.03 0.992 – 1.06 0.143 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 1.04 1 – 1.08 0.0512 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.02 0.845 – 1.24 0.822 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.968 0.892 – 1.05 0.429 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.971 0.892 – 1.06 0.508 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1 0.961 – 1.05 0.845 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 1.04 0.957 – 1.12 0.379 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 0.953 0.859 – 1.06 0.362 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.987 0.93 – 1.05 0.657 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.04 0.892 – 1.22 0.599 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.01 0.983 – 1.03 0.556 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.02 0.993 – 1.06 0.131 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.05 0.925 – 1.2 0.427 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.05 1 – 1.1 0.0365 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 0.999 0.935 – 1.07 0.97 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.03 0.979 – 1.09 0.233 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.02 0.963 – 1.09 0.456 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 1.02 0.962 – 1.09 0.449 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 1.05 0.869 – 1.26 0.637 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 0.969 0.932 – 1.01 0.108 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 1.07 0.967 – 1.17 0.202 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 0.997 0.832 – 1.19 0.971 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.01 0.945 – 1.08 0.737 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.978 0.879 – 1.09 0.685 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.944 0.826 – 1.08 0.402 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.702 0.541 – 0.913 0.00816 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.02 0.999 – 1.04 0.0571 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 1.02 0.999 – 1.04 0.0602 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 0.961 0.767 – 1.2 0.725 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.08 0.836 – 1.39 0.57 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.959 0.842 – 1.09 0.527 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 0.946 0.82 – 1.09 0.448 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.894 0.75 – 1.06 0.208 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.03 0.906 – 1.17 0.648 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 0.999 0.975 – 1.02 0.906 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.997 0.973 – 1.02 0.791 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.04 0.941 – 1.14 0.465 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 1.02 0.957 – 1.08 0.581 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 1.01 0.944 – 1.07 0.872 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 1.02 0.949 – 1.1 0.561 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1 0.86 – 1.16 0.996 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 0.933 0.807 – 1.08 0.348 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 0.966 0.734 – 1.27 0.807 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 0.948 0.804 – 1.12 0.526 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 0.968 0.741 – 1.26 0.81 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.907 0.729 – 1.13 0.378 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.15 0.963 – 1.37 0.122 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.06 0.873 – 1.3 0.535 103 1059 all phecode
284 Aplastic anemia Hematopoietic 1.02 0.922 – 1.13 0.713 435 4357 all phecode
285 Other anemias Hematopoietic 1 0.983 – 1.02 0.861 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.03 0.912 – 1.17 0.595 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.03 0.95 – 1.11 0.505 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.01 0.909 – 1.11 0.911 414 4147 all phecode
286 Coagulation defects Hematopoietic 1.05 0.979 – 1.12 0.178 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 0.996 0.905 – 1.1 0.928 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 0.992 0.805 – 1.22 0.937 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.982 0.872 – 1.11 0.767 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 0.995 0.775 – 1.28 0.967 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.91 0.724 – 1.14 0.42 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.13 1.02 – 1.26 0.0207 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.02 0.966 – 1.07 0.548 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.09 0.903 – 1.3 0.383 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 1.01 0.772 – 1.32 0.954 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 1.01 0.961 – 1.07 0.658 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.12 1.01 – 1.23 0.0269 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.07 0.85 – 1.36 0.546 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 1.04 1.01 – 1.08 0.0221 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 1.04 1 – 1.08 0.0268 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 1.04 1.01 – 1.08 0.0248 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 1.13 0.884 – 1.44 0.335 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.05 0.974 – 1.12 0.215 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.11 0.982 – 1.25 0.0958 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 1.02 0.98 – 1.06 0.324 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 1.1 1 – 1.2 0.0495 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.09 0.968 – 1.22 0.158 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 0.985 0.796 – 1.22 0.889 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.943 0.901 – 0.988 0.0139 1929 19281 all phecode
290.1 Dementias Mental Disorders 0.922 0.864 – 0.983 0.0129 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 0.852 0.772 – 0.941 0.00161 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 0.959 0.831 – 1.11 0.561 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.932 0.861 – 1.01 0.0851 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.08 0.85 – 1.37 0.535 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.02 0.946 – 1.09 0.667 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.02 0.855 – 1.21 0.832 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.992 0.877 – 1.12 0.893 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 1.04 0.943 – 1.15 0.426 436 4376 all phecode
292 Neurological disorders Mental Disorders 0.992 0.963 – 1.02 0.623 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1 0.954 – 1.06 0.856 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 1.02 0.878 – 1.19 0.77 190 1907 all phecode
292.3 Memory loss Mental Disorders 0.957 0.886 – 1.03 0.27 696 6978 all phecode
292.4 Altered mental status Mental Disorders 1 0.961 – 1.05 0.844 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 0.958 0.855 – 1.07 0.456 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 0.969 0.927 – 1.01 0.168 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.06 0.991 – 1.14 0.088 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.966 0.901 – 1.04 0.342 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 0.969 0.89 – 1.05 0.46 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 1.08 0.926 – 1.26 0.333 178 1780 all phecode
295.3 Psychosis Mental Disorders 1.01 0.864 – 1.18 0.886 169 1710 all phecode
296 Mood disorders Mental Disorders 1.01 0.989 – 1.03 0.414 12372 123822 all phecode
296.1 Bipolar Mental Disorders 0.989 0.929 – 1.05 0.723 1059 10599 all phecode
296.2 Depression Mental Disorders 1.01 0.992 – 1.03 0.276 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 0.933 0.838 – 1.04 0.204 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.991 0.884 – 1.11 0.876 311 3070 all phecode
300 Anxiety disorders Mental Disorders 1 0.977 – 1.03 0.932 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 1 0.978 – 1.03 0.778 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 0.879 0.745 – 1.04 0.128 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.03 0.953 – 1.11 0.46 707 7065 all phecode
300.13 Phobia Mental Disorders 1.02 0.935 – 1.12 0.614 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.03 0.869 – 1.22 0.723 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 1.26 0.954 – 1.67 0.103 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 0.971 0.814 – 1.16 0.741 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.966 0.802 – 1.17 0.721 113 1129 all phecode
301 Personality disorders Mental Disorders 0.989 0.886 – 1.1 0.846 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.961 0.796 – 1.16 0.681 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.899 0.8 – 1.01 0.074 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.955 0.868 – 1.05 0.341 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 0.956 0.857 – 1.07 0.42 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 0.929 0.777 – 1.11 0.421 123 1229 all phecode
304 Adjustment reaction Mental Disorders 1.05 0.933 – 1.18 0.419 293 2936 all phecode
305.2 Eating disorder Mental Disorders 1.1 0.879 – 1.38 0.399 90 900 all phecode
306 Other mental disorder Mental Disorders 1.01 0.996 – 1.02 0.197 28056 230087 all phecode
306.9 Tension headache Mental Disorders 0.976 0.868 – 1.1 0.688 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 0.876 0.697 – 1.1 0.257 76 770 all phecode
313.3 Autism Mental Disorders 0.958 0.721 – 1.27 0.765 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 1.04 0.93 – 1.16 0.504 351 3517 all phecode
315.1 Learning disorder Mental Disorders 0.976 0.829 – 1.15 0.769 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 1.13 0.902 – 1.41 0.292 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 1.01 0.979 – 1.04 0.617 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.875 0.672 – 1.14 0.322 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 1 0.983 – 1.02 0.88 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 0.997 0.976 – 1.02 0.799 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 0.924 0.861 – 0.992 0.0281 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 1.01 0.991 – 1.02 0.455 19359 185465 all phecode
320 Meningitis Neurological 0.933 0.847 – 1.03 0.164 444 4447 all phecode
323 Encephalitis Neurological 1.04 0.933 – 1.16 0.468 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 1.1 0.868 – 1.4 0.425 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 0.936 0.834 – 1.05 0.261 292 2916 all phecode
327 Sleep disorders Neurological 1.01 0.948 – 1.07 0.826 1164 11659 all phecode
327.3 Sleep apnea Neurological 0.985 0.955 – 1.02 0.329 4428 44318 all phecode
327.4 Insomnia Neurological 1.11 0.943 – 1.3 0.216 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 1.2 1.01 – 1.43 0.0422 136 1390 all phecode
331 Other cerebral degenerations Neurological 0.985 0.927 – 1.05 0.635 1142 11416 all phecode
331.1 Hydrocephalus Neurological 1.04 0.95 – 1.14 0.381 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 0.977 0.885 – 1.08 0.642 430 4298 all phecode
332 Parkinson's disease Neurological 0.976 0.918 – 1.04 0.433 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.01 0.944 – 1.08 0.752 894 8954 all phecode
333.1 Essential tremor Neurological 0.983 0.856 – 1.13 0.809 216 2157 all phecode
333.2 Myoclonus Neurological 0.978 0.795 – 1.2 0.83 96 958 all phecode
333.4 Torsion dystonia Neurological 1.03 0.902 – 1.17 0.704 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 1.01 0.961 – 1.06 0.736 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 0.987 0.814 – 1.2 0.896 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 1.06 0.934 – 1.21 0.353 245 2446 all phecode
335 Multiple sclerosis Neurological 0.968 0.915 – 1.02 0.254 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 0.996 0.877 – 1.13 0.949 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 0.847 0.67 – 1.07 0.164 72 719 all phecode
338 Pain Neurological 1.08 1 – 1.16 0.0435 768 7692 all phecode
338.1 Acute pain Neurological 1.08 0.97 – 1.19 0.168 394 3937 all phecode
338.2 Chronic pain Neurological 1.08 0.967 – 1.2 0.178 380 3817 all phecode
339 Other headache syndromes Neurological 1.01 0.988 – 1.04 0.343 7819 78241 all phecode
340 Migraine Neurological 1.03 0.99 – 1.07 0.154 2860 28602 all phecode
340.1 Migrain with aura Neurological 0.924 0.805 – 1.06 0.268 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.993 0.875 – 1.13 0.915 252 2535 all phecode
342 Hemiplegia Neurological 1.04 0.986 – 1.1 0.145 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 0.958 0.809 – 1.13 0.615 145 1450 all phecode
344 Other paralytic syndromes Neurological 0.98 0.904 – 1.06 0.617 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1 0.972 – 1.03 0.961 5023 50270 all phecode
345.1 Epilepsy Neurological 0.942 0.878 – 1.01 0.0954 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 0.948 0.86 – 1.05 0.287 439 4385 all phecode
345.12 Partial epilepsy Neurological 0.892 0.788 – 1.01 0.0731 277 2776 all phecode
345.3 Convulsions Neurological 0.972 0.931 – 1.02 0.203 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.23 1.04 – 1.46 0.0163 144 1438 all phecode
348 Other conditions of brain Neurological 0.993 0.922 – 1.07 0.844 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 0.994 0.876 – 1.13 0.924 268 2678 all phecode
348.4 Cerebral cysts Neurological 1.07 0.893 – 1.28 0.468 133 1350 all phecode
348.7 Coma Neurological 1.02 0.919 – 1.14 0.669 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.03 0.906 – 1.17 0.656 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 1.07 0.959 – 1.18 0.239 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.97 0.866 – 1.09 0.591 342 3414 all phecode
350 Abnormal movement Neurological 0.994 0.955 – 1.03 0.761 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 0.92 0.858 – 0.986 0.0177 887 8852 all phecode
350.2 Abnormality of gait Neurological 1.02 0.965 – 1.07 0.544 1596 15969 all phecode
350.3 Lack of coordination Neurological 1.04 0.931 – 1.16 0.509 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.936 0.709 – 1.24 0.643 54 540 all phecode
351 Other peripheral nerve disorders Neurological 1.01 0.987 – 1.02 0.53 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 1.03 0.974 – 1.09 0.297 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.09 0.986 – 1.2 0.0935 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.02 0.951 – 1.09 0.576 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 0.999 0.94 – 1.06 0.965 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 1.04 0.855 – 1.26 0.716 114 1138 all phecode
353.2 Nerve root lesions Neurological 1.07 0.804 – 1.43 0.641 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.995 0.844 – 1.17 0.954 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.02 0.964 – 1.08 0.507 1361 13648 all phecode
358 Myoneural disorders Neurological 0.989 0.857 – 1.14 0.88 211 2109 all phecode
358.1 Myasthenia gravis Neurological 0.991 0.851 – 1.15 0.902 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 1.04 0.945 – 1.14 0.432 465 4646 all phecode
359.1 Muscular dystrophies Neurological 0.901 0.749 – 1.08 0.27 122 1219 all phecode
359.2 Myopathy Neurological 1.09 0.977 – 1.21 0.124 360 3597 all phecode
360 Disorders of the globe Sense Organs 0.937 0.841 – 1.04 0.24 337 3367 all phecode
360.2 Progressive myopia Sense Organs 0.892 0.787 – 1.01 0.0753 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 1.03 0.99 – 1.06 0.163 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.01 0.956 – 1.07 0.698 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.981 0.776 – 1.24 0.874 68 680 all phecode
362 Other retinal disorders Sense Organs 0.986 0.954 – 1.02 0.406 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.01 0.969 – 1.06 0.579 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.01 0.969 – 1.06 0.583 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.02 0.865 – 1.19 0.845 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 0.957 0.781 – 1.17 0.674 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.969 0.904 – 1.04 0.372 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 1.08 0.927 – 1.27 0.313 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.984 0.786 – 1.23 0.885 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.896 0.746 – 1.08 0.243 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.95 0.809 – 1.12 0.533 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 0.812 0.633 – 1.04 0.1 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.955 0.882 – 1.03 0.263 647 6485 all phecode
364.1 Corneal opacity Sense Organs 0.925 0.747 – 1.15 0.475 90 910 all phecode
364.2 Corneal edema Sense Organs 0.85 0.684 – 1.06 0.145 79 800 all phecode
364.4 Corneal degenerations Sense Organs 1.05 0.907 – 1.21 0.52 201 2017 all phecode
364.41 Keratoconus Sense Organs 0.904 0.729 – 1.12 0.356 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 0.892 0.776 – 1.03 0.107 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.995 0.809 – 1.22 0.965 100 1000 all phecode
365 Glaucoma Sense Organs 1.01 0.975 – 1.04 0.712 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 0.995 0.933 – 1.06 0.865 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 0.988 0.927 – 1.05 0.721 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.965 0.893 – 1.04 0.366 698 6996 all phecode
366 Cataract Sense Organs 0.992 0.978 – 1.01 0.297 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 1.16 0.915 – 1.46 0.224 69 700 all phecode
366.2 Senile cataract Sense Organs 0.995 0.972 – 1.02 0.643 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 1.12 0.916 – 1.37 0.269 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.971 0.931 – 1.01 0.168 2408 24092 all phecode
367.1 Myopia Sense Organs 0.972 0.917 – 1.03 0.333 1251 12519 all phecode
367.2 Astigmatism Sense Organs 0.829 0.717 – 0.959 0.0116 190 1899 all phecode
367.8 Hypermetropia Sense Organs 0.995 0.873 – 1.13 0.936 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 0.983 0.912 – 1.06 0.666 719 7198 all phecode
368 Visual disturbances Sense Organs 0.996 0.96 – 1.03 0.85 2962 29648 all phecode
368.1 Amblyopia Sense Organs 0.993 0.908 – 1.09 0.873 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.02 0.948 – 1.1 0.56 727 7288 all phecode
368.3 Anisometropia Sense Organs 0.898 0.762 – 1.06 0.199 154 1548 all phecode
368.4 Visual field defects Sense Organs 0.961 0.859 – 1.07 0.484 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 0.999 0.921 – 1.08 0.982 612 6115 all phecode
369 Infection of the eye Sense Organs 1.08 0.983 – 1.18 0.114 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 0.96 0.803 – 1.15 0.658 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 1.16 1.01 – 1.34 0.0408 213 2128 all phecode
370 Keratitis Sense Organs 1.06 0.939 – 1.2 0.337 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 1.05 0.884 – 1.25 0.578 141 1408 all phecode
371 Inflammation of the eye Sense Organs 0.995 0.959 – 1.03 0.789 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.945 0.862 – 1.04 0.228 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 1.01 0.966 – 1.05 0.724 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 0.993 0.921 – 1.07 0.845 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 1.01 0.979 – 1.03 0.687 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 0.984 0.924 – 1.05 0.612 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 0.999 0.952 – 1.05 0.978 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 1.01 0.964 – 1.05 0.754 2204 22031 all phecode
375.2 Epiphora Sense Organs 1.04 0.974 – 1.12 0.229 898 8969 all phecode
376 Disorders of the orbit Sense Organs 0.87 0.698 – 1.08 0.217 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.07 0.956 – 1.19 0.252 361 3618 all phecode
377.1 Optic atrophy Sense Organs 1.11 0.846 – 1.45 0.459 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.08 0.902 – 1.29 0.408 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.01 0.952 – 1.06 0.852 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1 0.937 – 1.07 0.936 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.92 0.801 – 1.06 0.236 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 1.03 0.913 – 1.17 0.597 275 2755 all phecode
379 Other disorders of eye Sense Organs 0.989 0.956 – 1.02 0.527 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 0.997 0.943 – 1.05 0.918 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.974 0.929 – 1.02 0.282 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 0.887 0.693 – 1.13 0.339 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.999 0.901 – 1.11 0.979 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.03 0.878 – 1.2 0.73 169 1690 all phecode
380 Disorders of external ear Sense Organs 1.02 0.94 – 1.11 0.639 642 6413 all phecode
380.1 Otitis externa Sense Organs 0.946 0.865 – 1.03 0.224 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 1.02 0.914 – 1.13 0.75 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.985 0.943 – 1.03 0.514 2150 21493 all phecode
381.1 Otitis media Sense Organs 0.987 0.94 – 1.04 0.585 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.964 0.898 – 1.04 0.313 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 0.941 0.814 – 1.09 0.405 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 0.954 0.816 – 1.12 0.552 171 1709 all phecode
381.9 Otorrhea Sense Organs 0.945 0.836 – 1.07 0.367 281 2807 all phecode
382 Otalgia Sense Organs 1.1 0.979 – 1.24 0.107 308 3084 all phecode
383 Otosclerosis Sense Organs 0.999 0.891 – 1.12 0.982 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.03 0.973 – 1.09 0.301 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.04 0.971 – 1.1 0.283 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.05 0.975 – 1.13 0.202 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 1.01 0.933 – 1.1 0.752 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.14 0.999 – 1.31 0.0517 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.998 0.95 – 1.05 0.928 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 0.957 0.878 – 1.04 0.31 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 1.01 0.906 – 1.12 0.889 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 1.01 0.936 – 1.08 0.854 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.01 0.984 – 1.05 0.367 4582 45806 all phecode
388 Other disorders of ear Sense Organs 1.01 0.877 – 1.16 0.882 202 2017 all phecode
389 Hearing loss Sense Organs 0.998 0.967 – 1.03 0.882 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.948 0.863 – 1.04 0.262 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 0.852 0.775 – 0.937 0.00097 450 4497 all phecode
389.4 Tinnitus Sense Organs 1.02 0.934 – 1.12 0.628 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1 0.975 – 1.03 0.789 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 0.987 0.95 – 1.02 0.477 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 1.03 0.976 – 1.1 0.258 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.01 0.951 – 1.08 0.701 1058 10566 all phecode
395 Heart valve disorders Circulatory System 0.993 0.963 – 1.03 0.683 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.984 0.947 – 1.02 0.391 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.954 0.846 – 1.07 0.435 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.19 0.969 – 1.45 0.098 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.883 0.716 – 1.09 0.242 97 970 all phecode
395.6 Heart valve replaced Circulatory System 1 0.95 – 1.06 0.936 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 0.966 0.906 – 1.03 0.288 1048 10468 all phecode
401 Hypertension Circulatory System 1.01 1 – 1.02 0.029 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 1.01 1 – 1.02 0.0249 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.02 0.971 – 1.07 0.464 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 0.957 0.861 – 1.06 0.417 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.04 0.983 – 1.09 0.192 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 1.07 0.898 – 1.27 0.457 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 0.996 0.944 – 1.05 0.869 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 0.991 0.98 – 1 0.16 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.984 0.956 – 1.01 0.251 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 0.976 0.957 – 0.994 0.00937 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 0.993 0.977 – 1.01 0.401 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 0.98 0.965 – 0.994 0.00575 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.01 0.938 – 1.09 0.745 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.99 0.974 – 1.01 0.24 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.977 0.922 – 1.04 0.43 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 0.97 0.925 – 1.02 0.2 1823 18228 all phecode
414.2 ASCVD Circulatory System 1.12 0.884 – 1.41 0.352 72 719 all phecode
415 Pulmonary heart disease Circulatory System 0.998 0.968 – 1.03 0.917 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.09 0.863 – 1.39 0.456 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.996 0.916 – 1.08 0.916 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.02 0.925 – 1.12 0.706 448 4475 all phecode
416 Cardiomegaly Circulatory System 0.99 0.953 – 1.03 0.629 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 0.99 0.978 – 1 0.117 28599 270106 all phecode
418.1 Precordial pain Circulatory System 0.98 0.946 – 1.01 0.24 3551 35541 all phecode
420 Carditis Circulatory System 1.01 0.961 – 1.05 0.821 2106 21053 all phecode
420.1 Myocarditis Circulatory System 1.05 0.879 – 1.26 0.579 127 1267 all phecode
420.2 Pericarditis Circulatory System 1.01 0.951 – 1.06 0.837 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 1.06 0.924 – 1.21 0.412 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 1.08 0.892 – 1.31 0.428 113 1129 all phecode
420.3 Endocarditis Circulatory System 0.979 0.907 – 1.06 0.576 719 7194 all phecode
425 Cardiomyopathy Circulatory System 1 0.948 – 1.06 0.891 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.996 0.94 – 1.06 0.884 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.948 0.798 – 1.13 0.546 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.962 0.821 – 1.13 0.63 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 0.988 0.765 – 1.28 0.928 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 1.01 0.987 – 1.04 0.363 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.02 0.978 – 1.07 0.328 2114 21162 all phecode
426.21 First degree AV block Circulatory System 1.02 0.959 – 1.09 0.478 986 9867 all phecode
426.23 Second degree AV block Circulatory System 0.974 0.885 – 1.07 0.599 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.06 0.97 – 1.15 0.211 587 5868 all phecode
426.25 Other heart block Circulatory System 1 0.839 – 1.2 0.988 131 1318 all phecode
426.3 Bundle branch block Circulatory System 0.995 0.96 – 1.03 0.788 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 0.998 0.946 – 1.05 0.937 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 0.988 0.94 – 1.04 0.617 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.915 0.802 – 1.05 0.191 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 0.994 0.769 – 1.29 0.966 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.04 0.993 – 1.08 0.104 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.02 0.98 – 1.07 0.301 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 1.01 0.999 – 1.03 0.0597 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.02 0.984 – 1.06 0.268 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.02 0.979 – 1.07 0.335 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.01 0.948 – 1.08 0.689 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.01 0.994 – 1.03 0.222 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.972 0.938 – 1.01 0.126 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.977 0.922 – 1.04 0.446 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.98 0.878 – 1.09 0.713 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 0.976 0.915 – 1.04 0.455 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.01 0.946 – 1.08 0.747 952 9541 all phecode
427.6 Premature beats Circulatory System 1.02 0.929 – 1.11 0.734 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 0.945 0.79 – 1.13 0.532 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 1.06 1.01 – 1.11 0.0095 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.969 0.875 – 1.07 0.549 402 4029 all phecode
427.9 Palpitations Circulatory System 1.02 0.985 – 1.05 0.28 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.987 0.961 – 1.01 0.356 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 0.98 0.938 – 1.02 0.37 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 1 0.971 – 1.03 0.949 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.08 0.999 – 1.17 0.0523 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 1.07 0.827 – 1.38 0.606 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.07 0.979 – 1.18 0.132 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.08 0.937 – 1.25 0.278 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 1.05 1 – 1.11 0.0311 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.1 1.02 – 1.18 0.00975 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1.06 0.984 – 1.14 0.125 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 1 0.883 – 1.13 0.985 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 0.999 0.978 – 1.02 0.952 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.975 0.919 – 1.04 0.415 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1 0.872 – 1.15 0.995 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.991 0.96 – 1.02 0.561 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.996 0.947 – 1.05 0.873 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 0.98 0.944 – 1.02 0.303 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 0.981 0.939 – 1.03 0.398 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 1.14 1.02 – 1.26 0.0158 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.02 0.966 – 1.08 0.434 1279 12783 all phecode
440 Atherosclerosis Circulatory System 1.02 0.967 – 1.08 0.456 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.09 0.904 – 1.32 0.357 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.05 0.975 – 1.13 0.203 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 0.871 0.773 – 0.98 0.0218 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.05 0.965 – 1.14 0.252 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.08 0.95 – 1.22 0.248 283 2827 all phecode
442 Other aneurysm Circulatory System 1.05 1.01 – 1.11 0.0273 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 1.04 0.986 – 1.1 0.152 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.01 0.947 – 1.08 0.716 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 0.972 0.797 – 1.19 0.778 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.11 0.946 – 1.29 0.204 169 1696 all phecode
442.4 Arterial dissection Circulatory System 1.27 0.968 – 1.67 0.0845 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.11 0.963 – 1.28 0.147 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 1.01 0.98 – 1.05 0.453 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 1.05 0.985 – 1.11 0.139 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.05 0.947 – 1.17 0.349 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.01 0.977 – 1.05 0.537 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.99 0.951 – 1.03 0.626 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 0.983 0.92 – 1.05 0.625 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.984 0.902 – 1.07 0.706 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.99 0.923 – 1.06 0.791 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 0.923 0.796 – 1.07 0.288 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 0.998 0.901 – 1.11 0.977 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 0.915 0.805 – 1.04 0.179 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 0.999 0.944 – 1.06 0.967 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 1.01 0.945 – 1.09 0.702 868 8712 all phecode
448 Disease of capillaries Circulatory System 0.902 0.762 – 1.07 0.233 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.05 0.97 – 1.13 0.232 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.982 0.95 – 1.01 0.266 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.982 0.95 – 1.02 0.292 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 1 0.918 – 1.09 0.99 564 5645 all phecode
454 Varicose veins Circulatory System 1 0.985 – 1.02 0.628 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1 0.986 – 1.02 0.612 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.04 0.959 – 1.13 0.338 624 6325 all phecode
455 Hemorrhoids Circulatory System 1 0.988 – 1.02 0.821 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.947 0.819 – 1.09 0.461 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.86 0.697 – 1.06 0.158 97 967 all phecode
458 Hypotension Circulatory System 0.997 0.97 – 1.02 0.828 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 1.04 0.979 – 1.1 0.219 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.1 0.961 – 1.26 0.166 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 0.978 0.944 – 1.01 0.205 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 1.01 0.993 – 1.03 0.288 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 0.836 0.704 – 0.992 0.0404 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 1.01 0.995 – 1.03 0.191 16103 159422 all phecode
464 Acute sinusitis Respiratory 0.912 0.79 – 1.05 0.207 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.03 0.987 – 1.08 0.176 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 1.06 0.987 – 1.14 0.111 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.07 0.908 – 1.25 0.432 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.991 0.962 – 1.02 0.547 4654 46553 all phecode
471 Nasal polyps Respiratory 0.988 0.953 – 1.02 0.492 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.05 0.981 – 1.12 0.166 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1 0.961 – 1.04 0.991 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 1.08 0.885 – 1.32 0.442 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.927 0.82 – 1.05 0.221 264 2647 all phecode
473.4 Voice disturbance Respiratory 1 0.941 – 1.06 0.987 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 0.999 0.952 – 1.05 0.977 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 1.03 0.948 – 1.13 0.452 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.967 0.909 – 1.03 0.278 1122 11199 all phecode
475 Chronic sinusitis Respiratory 0.99 0.95 – 1.03 0.61 2589 25882 all phecode
476 Allergic rhinitis Respiratory 0.981 0.921 – 1.05 0.559 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 0.99 0.95 – 1.03 0.633 2447 24452 all phecode
478 Throat pain Respiratory 0.99 0.891 – 1.1 0.855 377 3789 all phecode
479 Other upper respiratory disease Respiratory 0.995 0.964 – 1.03 0.779 4074 40737 all phecode
480 Pneumonia Respiratory 1.01 0.99 – 1.03 0.321 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 1.02 0.991 – 1.04 0.209 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.02 0.991 – 1.04 0.208 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 0.868 0.706 – 1.07 0.179 93 929 all phecode
480.2 Viral pneumonia Respiratory 1.11 0.862 – 1.42 0.43 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.87 0.711 – 1.06 0.176 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.03 0.959 – 1.11 0.398 794 7951 all phecode
481 Influenza Respiratory 0.963 0.859 – 1.08 0.521 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.06 0.92 – 1.23 0.407 193 1930 all phecode
495 Asthma Respiratory 0.999 0.986 – 1.01 0.833 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 1.14 0.999 – 1.3 0.0519 250 2510 all phecode
496 Chronic airway obstruction Respiratory 0.995 0.975 – 1.02 0.635 10424 101546 all phecode
496.1 Emphysema Respiratory 0.954 0.908 – 1 0.0571 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 1 0.963 – 1.04 0.997 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.01 0.973 – 1.05 0.568 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 0.95 0.906 – 0.996 0.0343 1885 18859 all phecode
497 Bronchitis Respiratory 1.03 0.948 – 1.12 0.486 626 6267 all phecode
500 Lung disease due to external agents Respiratory 0.967 0.875 – 1.07 0.509 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.985 0.791 – 1.23 0.892 79 784 all phecode
500.2 Pneumoconiosis Respiratory 0.991 0.869 – 1.13 0.896 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.03 0.948 – 1.11 0.514 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.896 0.837 – 0.959 0.00146 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.06 0.964 – 1.16 0.238 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.919 0.823 – 1.03 0.138 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.04 0.796 – 1.37 0.762 61 610 all phecode
506 Empyema and pneumothorax Respiratory 1 0.943 – 1.07 0.941 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 0.996 0.971 – 1.02 0.754 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.972 0.928 – 1.02 0.232 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.01 0.968 – 1.05 0.702 2599 26031 all phecode
509.1 Respiratory failure Respiratory 1.02 0.979 – 1.07 0.292 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 1.02 0.972 – 1.07 0.424 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 0.926 0.784 – 1.09 0.364 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.939 0.846 – 1.04 0.234 386 3863 all phecode
510 Other diseases of lung Respiratory 0.996 0.925 – 1.07 0.921 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 0.978 0.957 – 1 0.0469 9031 90349 all phecode
512.1 Wheezing Respiratory 0.893 0.783 – 1.02 0.0931 220 2196 all phecode
512.2 Painful respiration Respiratory 0.962 0.834 – 1.11 0.6 207 2075 all phecode
512.7 Shortness of breath Respiratory 0.989 0.963 – 1.02 0.422 5842 58498 all phecode
512.8 Cough Respiratory 0.972 0.935 – 1.01 0.145 2866 28642 all phecode
512.9 Other dyspnea Respiratory 0.971 0.908 – 1.04 0.386 914 9124 all phecode
513 Respiratory abnormalities Respiratory 1.02 0.934 – 1.1 0.717 611 6112 all phecode
513.3 Hypoventilation Respiratory 0.987 0.787 – 1.24 0.909 83 830 all phecode
513.4 Hyperventilation Respiratory 1.08 0.956 – 1.23 0.21 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 0.854 0.725 – 1.01 0.0574 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 1.01 0.969 – 1.05 0.661 2465 24673 all phecode
516 Abnormal sputum Respiratory 1.02 0.976 – 1.07 0.382 2132 21335 all phecode
516.1 Hemoptysis Respiratory 1.02 0.975 – 1.07 0.4 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.992 0.971 – 1.01 0.457 9366 93681 all phecode
519.2 Respiratory complications Respiratory 0.989 0.882 – 1.11 0.843 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.992 0.97 – 1.01 0.463 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.04 0.92 – 1.17 0.549 303 3049 all phecode
520 Disorders of tooth development Digestive 0.984 0.94 – 1.03 0.476 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.06 0.789 – 1.42 0.709 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 0.987 0.946 – 1.03 0.554 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 0.979 0.943 – 1.02 0.268 3016 30245 all phecode
521.1 Dental caries Digestive 0.98 0.945 – 1.02 0.298 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.03 0.98 – 1.08 0.255 1774 17750 all phecode
522.5 Periapical abscess Digestive 0.999 0.941 – 1.06 0.964 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 1.01 0.962 – 1.06 0.666 1681 16812 all phecode
523.1 Gingivitis Digestive 1.02 0.839 – 1.24 0.848 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.01 0.948 – 1.07 0.817 1165 11650 all phecode
523.31 Acute periodontitis Digestive 0.976 0.902 – 1.06 0.556 666 6667 all phecode
523.32 Chronic periodontitis Digestive 1 0.919 – 1.09 0.944 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.02 0.911 – 1.14 0.745 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.953 0.85 – 1.07 0.413 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.97 0.933 – 1.01 0.14 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.02 0.789 – 1.32 0.88 72 720 all phecode
526 Diseases of the jaws Digestive 1 0.938 – 1.07 0.919 928 9279 all phecode
526.1 Cysts of the jaws Digestive 0.938 0.839 – 1.05 0.257 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.09 0.835 – 1.41 0.537 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.13 0.991 – 1.3 0.068 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.12 0.977 – 1.29 0.104 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 1.01 0.832 – 1.24 0.887 110 1098 all phecode
526.9 Jaw disease NOS Digestive 0.998 0.873 – 1.14 0.982 233 2329 all phecode
527 Diseases of the salivary glands Digestive 1.02 0.94 – 1.1 0.693 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.13 0.901 – 1.42 0.287 84 838 all phecode
527.2 Sialoadenitis Digestive 1.01 0.907 – 1.13 0.851 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 1 0.783 – 1.28 0.995 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.01 0.841 – 1.21 0.911 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.03 0.995 – 1.06 0.1 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 1.08 0.981 – 1.18 0.119 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.09 0.982 – 1.21 0.106 389 3884 all phecode
528.12 Oral aphthae Digestive 1.03 0.826 – 1.28 0.803 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.994 0.855 – 1.16 0.933 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 0.918 0.766 – 1.1 0.358 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 0.866 0.704 – 1.06 0.173 94 940 all phecode
528.5 Diseases of lips Digestive 1.05 0.972 – 1.14 0.201 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.11 0.984 – 1.25 0.0907 308 3079 all phecode
528.7 Sialolithiasis Digestive 1.03 0.92 – 1.16 0.578 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 0.988 0.932 – 1.05 0.676 1232 12312 all phecode
529.1 Glossitis Digestive 0.989 0.879 – 1.11 0.855 299 2986 all phecode
530 Diseases of esophagus Digestive 1 0.991 – 1.01 0.657 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1 0.99 – 1.01 0.792 31253 272429 all phecode
530.11 GERD Digestive 1.01 0.996 – 1.02 0.174 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 0.989 0.961 – 1.02 0.447 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 1 0.98 – 1.02 0.984 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.971 0.923 – 1.02 0.247 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.04 0.991 – 1.09 0.112 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 1.1 1.01 – 1.2 0.0237 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.11 0.942 – 1.3 0.216 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.03 0.927 – 1.16 0.543 341 3416 all phecode
530.9 Heartburn Digestive 0.991 0.947 – 1.04 0.68 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.993 0.97 – 1.02 0.599 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1 0.924 – 1.09 0.963 637 6374 all phecode
531.2 Gastric ulcer Digestive 1 0.971 – 1.03 0.899 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 0.973 0.937 – 1.01 0.156 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.04 0.945 – 1.15 0.407 427 4268 all phecode
532 Dysphagia Digestive 1.02 0.993 – 1.05 0.157 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 0.996 0.984 – 1.01 0.524 28078 261548 all phecode
535.1 Acute gastritis Digestive 1.02 0.959 – 1.08 0.576 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 0.935 0.84 – 1.04 0.215 370 3687 all phecode
535.6 Duodenitis Digestive 0.992 0.969 – 1.02 0.499 7592 75928 all phecode
535.8 Other specified gastritis Digestive 1.01 0.985 – 1.03 0.492 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.06 0.873 – 1.28 0.574 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.06 0.936 – 1.2 0.354 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 0.994 0.959 – 1.03 0.734 3391 33907 all phecode
540 Appendiceal conditions Digestive 1 0.963 – 1.04 0.982 3088 30890 all phecode
540.1 Appendicitis Digestive 1 0.962 – 1.04 0.994 2895 28963 all phecode
540.11 Acute appendicitis Digestive 0.997 0.957 – 1.04 0.876 2601 26019 all phecode
550 Abdominal hernia Digestive 0.996 0.986 – 1.01 0.472 45429 282640 all phecode
550.1 Inguinal hernia Digestive 1.01 0.997 – 1.03 0.115 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 0.986 0.974 – 0.999 0.0313 26494 238953 all phecode
550.3 Femoral hernia Digestive 0.995 0.917 – 1.08 0.895 651 6504 all phecode
550.4 Umbilical hernia Digestive 0.981 0.949 – 1.01 0.257 3705 37072 all phecode
550.5 Ventral hernia Digestive 1.02 0.986 – 1.06 0.237 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.01 0.975 – 1.04 0.738 4444 44442 all phecode
555.1 Regional enteritis Digestive 1.03 0.98 – 1.08 0.249 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 0.997 0.961 – 1.03 0.853 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 0.986 0.902 – 1.08 0.746 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 1.01 0.943 – 1.07 0.869 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 1.01 0.934 – 1.1 0.77 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.87 0.774 – 0.977 0.0191 299 2987 all phecode
557.1 Celiac disease Digestive 0.971 0.926 – 1.02 0.228 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 1.01 0.998 – 1.03 0.091 15492 155105 all phecode
559 Ileostomy status Digestive 0.978 0.93 – 1.03 0.376 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.02 0.987 – 1.05 0.236 3936 39337 all phecode
560.1 Paralytic ileus Digestive 1.01 0.922 – 1.11 0.839 523 5231 all phecode
560.2 Impaction of intestine Digestive 1.05 0.923 – 1.19 0.472 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.01 0.936 – 1.08 0.868 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 1.01 0.977 – 1.05 0.5 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 0.991 0.975 – 1.01 0.28 15772 157686 all phecode
561.1 Diarrhea Digestive 0.998 0.908 – 1.1 0.974 466 4653 all phecode
561.2 Flatulence Digestive 0.995 0.947 – 1.05 0.861 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 1 0.987 – 1.01 0.978 26714 211692 all phecode
562.1 Diverticulosis Digestive 1 0.987 – 1.01 0.979 26672 211642 all phecode
563 Constipation Digestive 0.988 0.968 – 1.01 0.229 10314 103140 all phecode
564 Functional digestive disorders Digestive 0.997 0.983 – 1.01 0.692 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 0.993 0.966 – 1.02 0.642 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1 0.95 – 1.05 0.99 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 0.998 0.982 – 1.02 0.838 15186 151648 all phecode
565 Anal and rectal conditions Digestive 0.996 0.979 – 1.01 0.623 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 0.996 0.973 – 1.02 0.747 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.01 0.948 – 1.08 0.692 929 9293 all phecode
568 Other disorders of peritoneum Digestive 1.02 0.986 – 1.06 0.234 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.02 0.983 – 1.06 0.287 3101 30987 all phecode
569 Other disorders of intestine Digestive 1.01 0.979 – 1.04 0.494 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.949 0.802 – 1.12 0.546 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 0.982 0.896 – 1.08 0.705 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 1 0.965 – 1.04 0.896 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.02 0.967 – 1.07 0.535 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.02 0.836 – 1.24 0.858 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 0.977 0.858 – 1.11 0.725 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.969 0.907 – 1.03 0.344 976 9804 all phecode
571.81 Portal hypertension Digestive 0.966 0.884 – 1.06 0.441 528 5285 all phecode
572 Ascites (non malignant) Digestive 1.05 0.996 – 1.11 0.0685 1544 15454 all phecode
573 Other disorders of liver Digestive 1.02 0.97 – 1.08 0.414 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 0.995 0.802 – 1.23 0.964 96 960 all phecode
573.3 Hepatomegaly Digestive 0.968 0.862 – 1.09 0.587 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 1.01 0.942 – 1.08 0.793 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 1 0.967 – 1.04 0.934 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 0.87 0.758 – 0.999 0.048 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 1 0.985 – 1.02 0.85 15607 156123 all phecode
574.1 Cholelithiasis Digestive 0.998 0.981 – 1.02 0.851 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.983 0.932 – 1.04 0.532 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.01 0.983 – 1.04 0.431 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 1.02 0.981 – 1.06 0.305 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.997 0.958 – 1.04 0.866 2748 27523 all phecode
575 Other biliary tract disease Digestive 1.01 0.975 – 1.04 0.662 3867 38724 all phecode
575.1 Cholangitis Digestive 1.02 0.931 – 1.12 0.66 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 1.04 0.971 – 1.12 0.24 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 1.02 0.923 – 1.12 0.72 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 0.997 0.944 – 1.05 0.923 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 1.02 0.956 – 1.09 0.557 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.913 0.82 – 1.02 0.1 348 3488 all phecode
577 Diseases of pancreas Digestive 0.989 0.951 – 1.03 0.592 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 0.995 0.95 – 1.04 0.824 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 0.958 0.878 – 1.05 0.336 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.04 0.94 – 1.16 0.421 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 1 0.989 – 1.02 0.705 20626 206278 all phecode
578.1 Hematemesis Digestive 1 0.955 – 1.05 0.995 1958 19564 all phecode
578.2 Blood in stool Digestive 1.01 0.967 – 1.05 0.768 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1 0.985 – 1.02 0.735 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.995 0.967 – 1.02 0.731 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.02 0.964 – 1.07 0.568 1548 15498 all phecode
579.2 Splenomegaly Digestive 1.06 0.961 – 1.17 0.239 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.976 0.928 – 1.03 0.357 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.01 0.956 – 1.06 0.778 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 0.995 0.933 – 1.06 0.869 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.784 0.621 – 0.989 0.0404 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.988 0.83 – 1.18 0.894 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.01 0.943 – 1.08 0.755 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.01 0.921 – 1.11 0.807 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.921 0.809 – 1.05 0.218 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.931 0.819 – 1.06 0.277 253 2529 all phecode
585 Renal failure Genitourinary 1.01 0.983 – 1.03 0.554 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 1.02 0.988 – 1.05 0.239 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 0.989 0.938 – 1.04 0.688 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1 0.963 – 1.04 0.907 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 0.988 0.901 – 1.08 0.796 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.02 0.984 – 1.06 0.287 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.944 0.819 – 1.09 0.422 208 2089 all phecode
586.11 Small kidney Genitourinary 0.975 0.836 – 1.14 0.747 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 0.997 0.941 – 1.06 0.925 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.1 0.872 – 1.38 0.43 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.02 0.953 – 1.09 0.581 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 0.973 0.876 – 1.08 0.61 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 0.957 0.776 – 1.18 0.683 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 0.98 0.813 – 1.18 0.834 116 1158 all phecode
590 Pyelonephritis Genitourinary 1.04 0.985 – 1.1 0.151 1328 13285 all phecode
591 Urinary tract infection Genitourinary 1 0.981 – 1.02 0.976 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 0.999 0.962 – 1.04 0.942 2966 29661 all phecode
592.1 Cystitis Genitourinary 1 0.964 – 1.04 0.952 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 0.958 0.805 – 1.14 0.623 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 0.921 0.86 – 0.986 0.0186 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.962 0.843 – 1.1 0.562 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.978 0.838 – 1.14 0.78 165 1662 all phecode
593 Hematuria Genitourinary 0.997 0.981 – 1.01 0.685 16068 160204 all phecode
594 Urinary calculus Genitourinary 0.991 0.966 – 1.02 0.475 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 0.987 0.952 – 1.02 0.474 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.04 0.966 – 1.12 0.306 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 0.976 0.937 – 1.02 0.252 2401 24024 all phecode
594.8 Renal colic Genitourinary 0.953 0.911 – 0.996 0.0341 2050 20500 all phecode
595 Hydronephrosis Genitourinary 1.02 0.971 – 1.07 0.458 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 1 0.984 – 1.03 0.682 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 1.02 0.97 – 1.06 0.518 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 0.989 0.94 – 1.04 0.666 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.02 0.985 – 1.05 0.305 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.01 0.974 – 1.05 0.611 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 0.899 0.713 – 1.13 0.365 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.01 0.972 – 1.04 0.715 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.973 0.866 – 1.09 0.64 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.996 0.981 – 1.01 0.621 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 1.19 1.01 – 1.4 0.0339 166 1670 all phecode
599.2 Retention of urine Genitourinary 0.999 0.975 – 1.02 0.961 6718 67168 all phecode
599.3 Dysuria Genitourinary 1.03 0.967 – 1.09 0.392 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 0.982 0.961 – 1 0.117 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.03 0.993 – 1.06 0.131 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 0.971 0.8 – 1.18 0.766 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.02 0.788 – 1.31 0.893 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 1.02 0.974 – 1.07 0.379 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 1.01 0.991 – 1.03 0.305 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 1.01 0.963 – 1.05 0.771 2081 20818 all phecode
601.1 Prostatitis Genitourinary 1.01 0.96 – 1.06 0.698 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 0.942 0.828 – 1.07 0.369 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 1.02 0.955 – 1.09 0.542 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 0.95 0.731 – 1.23 0.7 59 588 all phecode
601.4 Balanoposthitis Genitourinary 0.965 0.856 – 1.09 0.554 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.06 0.942 – 1.19 0.338 303 3019 all phecode
602 Other disorders of prostate Genitourinary 1.01 0.957 – 1.07 0.687 1341 13408 all phecode
603 Other disorders of testis Genitourinary 1.01 0.963 – 1.05 0.772 2150 21512 all phecode
603.1 Hydrocele Genitourinary 0.972 0.92 – 1.03 0.307 1339 13402 all phecode
604 Disorders of penis Genitourinary 0.992 0.958 – 1.03 0.656 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.985 0.948 – 1.02 0.445 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 0.986 0.875 – 1.11 0.815 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 1.01 0.968 – 1.05 0.772 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.926 0.806 – 1.06 0.277 214 2138 all phecode
609.1 Infertility, male Genitourinary 0.987 0.776 – 1.26 0.919 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.839 0.717 – 0.982 0.0287 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 1.01 0.973 – 1.06 0.491 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 0.985 0.92 – 1.05 0.659 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.03 0.919 – 1.16 0.581 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 1.03 0.917 – 1.17 0.583 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 1.02 0.966 – 1.08 0.449 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.96 0.888 – 1.04 0.311 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.08 1.02 – 1.14 0.00445 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 0.919 0.694 – 1.22 0.558 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 1.09 1.04 – 1.15 0.00124 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.02 0.948 – 1.09 0.659 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.02 0.946 – 1.09 0.654 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 1.09 0.861 – 1.37 0.479 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 1.02 0.968 – 1.07 0.463 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.07 0.991 – 1.16 0.0824 720 7210 all phecode
613.5 Mastodynia Genitourinary 0.898 0.709 – 1.14 0.372 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 1.01 0.93 – 1.09 0.874 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 0.989 0.882 – 1.11 0.857 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 0.976 0.845 – 1.13 0.735 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.05 1.02 – 1.08 0.00151 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.03 0.985 – 1.07 0.208 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.04 0.971 – 1.12 0.251 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.919 0.703 – 1.2 0.534 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.08 0.976 – 1.19 0.139 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.02 0.909 – 1.14 0.774 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.05 0.926 – 1.19 0.457 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.06 1.01 – 1.1 0.00934 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.09 1.03 – 1.16 0.00285 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.01 0.912 – 1.12 0.836 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.05 0.97 – 1.13 0.244 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.03 0.91 – 1.16 0.646 274 2737 all phecode
615 Endometriosis Genitourinary 1.03 1 – 1.07 0.0474 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.14 1.01 – 1.28 0.0371 304 3037 all phecode
618 Genital prolapse Genitourinary 0.999 0.98 – 1.02 0.933 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1.01 0.987 – 1.04 0.388 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.983 0.956 – 1.01 0.236 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.959 0.876 – 1.05 0.357 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1 0.924 – 1.08 0.99 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.994 0.973 – 1.02 0.623 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.01 0.936 – 1.09 0.784 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1.01 0.978 – 1.05 0.468 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.981 0.944 – 1.02 0.336 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1 0.956 – 1.06 0.858 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.956 0.903 – 1.01 0.122 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 1.05 0.832 – 1.33 0.672 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 1 0.941 – 1.07 0.962 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 1.04 1.02 – 1.06 0.000274 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 1.04 1.01 – 1.06 0.00263 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 1.06 1.02 – 1.1 0.00131 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.01 0.952 – 1.07 0.764 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 0.994 0.924 – 1.07 0.881 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.973 0.85 – 1.11 0.69 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 1.01 0.91 – 1.11 0.911 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 0.979 0.953 – 1.01 0.124 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.05 1.01 – 1.09 0.0172 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 1.06 1 – 1.13 0.0401 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.03 1.02 – 1.05 0.000115 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.04 1.02 – 1.06 3.99e-05 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.881 0.723 – 1.07 0.207 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.05 1.03 – 1.07 8.89e-06 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 1.01 0.967 – 1.06 0.574 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 1.06 1.03 – 1.1 0.000641 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 1.06 1.01 – 1.11 0.0224 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.972 0.825 – 1.14 0.73 159 1587 all phecode
626.8 Infertility, female Genitourinary 1.03 0.972 – 1.09 0.323 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1 0.984 – 1.02 0.692 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 1 0.983 – 1.03 0.7 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 1.01 0.861 – 1.18 0.94 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.02 0.963 – 1.09 0.436 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 1.06 0.938 – 1.19 0.365 310 3097 all phecode
628 Ovarian cyst Genitourinary 1.07 1.04 – 1.11 3.62e-06 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.01 0.98 – 1.04 0.535 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.995 0.937 – 1.06 0.879 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.03 0.924 – 1.16 0.562 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1 0.956 – 1.05 0.939 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.03 0.959 – 1.1 0.433 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1 0.948 – 1.06 0.88 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.01 0.971 – 1.06 0.53 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.995 0.915 – 1.08 0.904 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.05 0.985 – 1.12 0.135 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 0.812 0.64 – 1.03 0.0875 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.954 0.896 – 1.02 0.137 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.903 0.803 – 1.01 0.0843 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.92 0.799 – 1.06 0.24 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.888 0.75 – 1.05 0.168 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 1 0.946 – 1.06 0.9 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.03 0.985 – 1.08 0.19 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.07 0.821 – 1.39 0.628 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.915 0.808 – 1.04 0.163 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.985 0.809 – 1.2 0.883 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.02 0.875 – 1.19 0.806 193 1922 all phecode
650 Normal delivery Pregnancy Complications 0.982 0.937 – 1.03 0.455 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 0.956 0.855 – 1.07 0.423 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1.03 0.977 – 1.08 0.286 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.983 0.93 – 1.04 0.556 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.09 0.853 – 1.39 0.495 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.02 0.992 – 1.06 0.143 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.928 0.762 – 1.13 0.46 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.995 0.952 – 1.04 0.841 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.967 0.883 – 1.06 0.458 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 1.01 0.976 – 1.04 0.687 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.02 0.98 – 1.07 0.32 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.04 0.888 – 1.22 0.616 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.05 0.926 – 1.2 0.428 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.819 0.637 – 1.05 0.121 63 624 all phecode
679 Complications of in utero procedures Dermatologic 1.03 0.766 – 1.38 0.863 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 0.997 0.973 – 1.02 0.813 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.02 0.937 – 1.11 0.635 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.05 0.956 – 1.15 0.33 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.996 0.969 – 1.02 0.78 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.998 0.971 – 1.03 0.891 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.996 0.969 – 1.02 0.773 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1 0.924 – 1.09 0.918 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.02 0.962 – 1.08 0.537 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 0.965 0.924 – 1.01 0.0993 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 1.03 0.947 – 1.12 0.477 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 1.01 0.903 – 1.12 0.912 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1.06 0.974 – 1.16 0.166 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1 0.96 – 1.05 0.871 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.13 0.993 – 1.28 0.0631 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 0.994 0.816 – 1.21 0.956 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 0.994 0.957 – 1.03 0.762 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.01 0.982 – 1.04 0.537 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 1.17 0.929 – 1.48 0.181 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 1.11 0.846 – 1.44 0.463 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 0.946 0.787 – 1.14 0.557 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.978 0.916 – 1.04 0.508 986 9854 all phecode
694.1 Vitiligo Dermatologic 0.974 0.744 – 1.27 0.847 60 599 all phecode
694.2 Other dyschromia Dermatologic 0.975 0.906 – 1.05 0.495 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 0.919 0.762 – 1.11 0.38 117 1170 all phecode
695 Erythematous conditions Dermatologic 1.02 0.98 – 1.07 0.297 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 0.914 0.749 – 1.11 0.373 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 0.952 0.805 – 1.13 0.568 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 0.855 0.673 – 1.09 0.199 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.06 0.834 – 1.34 0.646 73 727 all phecode
695.3 Rosacea Dermatologic 1.08 0.959 – 1.22 0.205 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.07 0.961 – 1.18 0.225 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.971 0.81 – 1.16 0.75 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.06 0.947 – 1.19 0.314 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 1.05 0.972 – 1.13 0.229 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 0.92 0.806 – 1.05 0.213 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 0.788 0.623 – 0.997 0.0467 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 0.998 0.906 – 1.1 0.965 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 0.996 0.954 – 1.04 0.855 2252 22509 all phecode
696.4 Psoriasis Dermatologic 0.99 0.948 – 1.03 0.658 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 0.983 0.935 – 1.03 0.492 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.02 0.94 – 1.1 0.692 706 7052 all phecode
697 Sarcoidosis Dermatologic 1.01 0.922 – 1.1 0.876 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 0.976 0.906 – 1.05 0.527 782 7814 all phecode
700 Corns and callosities Dermatologic 0.991 0.881 – 1.11 0.878 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.01 0.979 – 1.04 0.569 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 0.959 0.771 – 1.19 0.704 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.01 0.968 – 1.05 0.65 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.02 0.785 – 1.32 0.898 61 610 all phecode
701.4 Keloid scar Dermatologic 0.997 0.866 – 1.15 0.972 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 1 0.907 – 1.1 0.998 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.3 1.05 – 1.6 0.016 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.965 0.938 – 0.992 0.0115 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 1 0.962 – 1.04 0.949 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 0.922 0.889 – 0.956 1.44e-05 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 1.02 0.911 – 1.13 0.777 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 0.978 0.917 – 1.04 0.511 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 0.984 0.957 – 1.01 0.272 5267 52727 all phecode
704.1 Alopecia Dermatologic 0.971 0.811 – 1.16 0.751 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.868 0.689 – 1.1 0.233 76 759 all phecode
705 Disorders of sweat glands Dermatologic 0.882 0.767 – 1.01 0.0757 228 2287 all phecode
705.3 Hidradenitis Dermatologic 0.915 0.785 – 1.07 0.253 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 0.962 0.885 – 1.05 0.365 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 0.989 0.967 – 1.01 0.33 8317 83195 all phecode
706.1 Acne Dermatologic 0.801 0.637 – 1.01 0.0567 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 0.994 0.972 – 1.02 0.593 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 0.993 0.948 – 1.04 0.75 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 0.971 0.908 – 1.04 0.388 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.988 0.954 – 1.02 0.501 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 1.04 0.944 – 1.14 0.462 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 1.11 0.949 – 1.3 0.19 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.23 0.954 – 1.58 0.111 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.974 0.936 – 1.01 0.183 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.961 0.885 – 1.04 0.351 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 0.967 0.887 – 1.05 0.446 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.953 0.826 – 1.1 0.513 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.972 0.877 – 1.08 0.594 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.01 0.917 – 1.12 0.802 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 0.958 0.857 – 1.07 0.452 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 0.909 0.723 – 1.14 0.414 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.954 0.812 – 1.12 0.56 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.08 0.852 – 1.38 0.513 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1 0.972 – 1.03 0.954 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.01 0.981 – 1.04 0.453 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.994 0.945 – 1.04 0.803 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.938 0.775 – 1.14 0.516 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.994 0.916 – 1.08 0.88 618 6177 all phecode
716 Other arthropathies Musculoskeletal 1 0.992 – 1.01 0.591 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.02 0.983 – 1.05 0.322 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.01 0.99 – 1.02 0.443 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 1 0.992 – 1.01 0.632 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.01 0.948 – 1.07 0.823 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 0.968 0.936 – 1 0.0576 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 0.999 0.976 – 1.02 0.927 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.994 0.966 – 1.02 0.683 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.08 0.937 – 1.26 0.275 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 0.86 0.772 – 0.958 0.00623 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 0.996 0.975 – 1.02 0.724 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.981 0.896 – 1.07 0.675 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.999 0.961 – 1.04 0.948 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 0.966 0.767 – 1.22 0.768 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1 0.973 – 1.03 0.835 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 0.978 0.894 – 1.07 0.628 517 5173 all phecode
723.1 Torticollis Musculoskeletal 0.882 0.73 – 1.07 0.193 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.01 0.967 – 1.06 0.617 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 0.986 0.89 – 1.09 0.781 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 0.978 0.883 – 1.08 0.67 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.16 0.893 – 1.52 0.26 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.02 0.967 – 1.07 0.508 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.01 0.989 – 1.02 0.49 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 0.997 0.977 – 1.02 0.815 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 1.04 0.929 – 1.16 0.504 334 3336 all phecode
726.3 Bursitis Musculoskeletal 1.04 0.971 – 1.12 0.254 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1 0.979 – 1.03 0.797 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.01 0.967 – 1.05 0.779 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 0.977 0.805 – 1.18 0.811 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.02 0.982 – 1.06 0.313 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 0.971 0.892 – 1.06 0.492 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.04 0.932 – 1.16 0.476 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.972 0.823 – 1.15 0.739 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.999 0.966 – 1.03 0.957 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.04 0.937 – 1.15 0.482 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 1 0.972 – 1.04 0.779 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1 0.966 – 1.04 0.984 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.02 0.991 – 1.04 0.204 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.977 0.915 – 1.04 0.484 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 1.16 0.94 – 1.44 0.164 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.986 0.869 – 1.12 0.82 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.974 0.856 – 1.11 0.694 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 0.95 0.864 – 1.04 0.286 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.973 0.845 – 1.12 0.701 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.913 0.708 – 1.18 0.48 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.992 0.944 – 1.04 0.735 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 0.949 0.846 – 1.06 0.368 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.03 0.938 – 1.12 0.577 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 0.966 0.809 – 1.15 0.699 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.985 0.929 – 1.04 0.609 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 0.894 0.742 – 1.08 0.24 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 1 0.982 – 1.02 0.804 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 0.96 0.83 – 1.11 0.58 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 1.02 0.988 – 1.05 0.239 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.02 0.977 – 1.07 0.315 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 1.02 0.964 – 1.07 0.553 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.998 0.973 – 1.02 0.869 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.99 0.941 – 1.04 0.712 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.05 0.921 – 1.21 0.443 248 2476 all phecode
737 Curvature of spine Musculoskeletal 0.952 0.895 – 1.01 0.111 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.949 0.891 – 1.01 0.1 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.01 0.963 – 1.06 0.699 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.01 0.957 – 1.06 0.743 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 0.946 0.863 – 1.04 0.239 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 0.997 0.985 – 1.01 0.632 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.992 0.977 – 1.01 0.315 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.981 0.96 – 1 0.0891 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.04 0.929 – 1.16 0.515 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.06 0.973 – 1.15 0.185 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.01 0.988 – 1.03 0.482 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.02 0.989 – 1.06 0.176 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 1.03 0.841 – 1.26 0.782 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 1.02 0.937 – 1.11 0.678 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 0.962 0.814 – 1.14 0.648 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 1.04 0.984 – 1.1 0.172 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 1.06 0.873 – 1.29 0.55 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 1.3 0.975 – 1.75 0.0736 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.963 0.927 – 1 0.0581 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 0.935 0.839 – 1.04 0.222 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1 0.819 – 1.23 0.978 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 0.898 0.82 – 0.983 0.0194 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 0.987 0.942 – 1.03 0.571 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1 0.979 – 1.03 0.826 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 1 0.975 – 1.03 0.982 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.994 0.966 – 1.02 0.654 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1.02 0.935 – 1.12 0.631 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 0.946 0.865 – 1.04 0.228 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.05 0.973 – 1.12 0.226 815 8144 all phecode
745 Pain in joint Musculoskeletal 1.02 1 – 1.05 0.0521 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.02 0.979 – 1.06 0.363 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.01 0.972 – 1.05 0.566 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.977 0.897 – 1.06 0.589 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.998 0.876 – 1.14 0.98 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.01 0.96 – 1.06 0.771 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.07 0.917 – 1.26 0.377 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.04 0.78 – 1.39 0.778 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.884 0.786 – 0.993 0.0376 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 1.03 0.953 – 1.12 0.442 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.04 0.93 – 1.17 0.476 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.985 0.849 – 1.14 0.841 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.05 0.941 – 1.17 0.382 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1 0.873 – 1.15 0.979 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.17 0.971 – 1.41 0.0992 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.975 0.925 – 1.03 0.343 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.979 0.906 – 1.06 0.594 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.987 0.897 – 1.09 0.792 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.993 0.865 – 1.14 0.919 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.994 0.926 – 1.07 0.862 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 1.04 0.94 – 1.15 0.463 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.947 0.847 – 1.06 0.344 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.99 0.883 – 1.11 0.859 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 1 0.882 – 1.14 0.953 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 1.06 0.914 – 1.22 0.453 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.978 0.782 – 1.22 0.845 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.995 0.828 – 1.2 0.96 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.07 0.846 – 1.36 0.569 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.03 0.846 – 1.25 0.768 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.02 0.924 – 1.13 0.659 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 1 0.866 – 1.16 0.969 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.95 0.803 – 1.12 0.551 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.01 0.824 – 1.24 0.912 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.02 0.936 – 1.11 0.66 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.17 0.925 – 1.47 0.194 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.961 0.87 – 1.06 0.43 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.11 0.942 – 1.31 0.208 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.21 0.933 – 1.57 0.15 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.06 0.924 – 1.22 0.395 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.1 0.887 – 1.35 0.397 96 959 all phecode
760 Back pain Symptoms 1.01 0.989 – 1.03 0.409 11126 111353 all phecode
761 Cervicalgia Symptoms 0.995 0.948 – 1.05 0.855 1791 17901 all phecode
764 Sciatica Symptoms 1.02 0.98 – 1.07 0.302 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.957 0.902 – 1.02 0.145 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 0.981 0.905 – 1.06 0.633 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.06 0.99 – 1.14 0.0946 870 8687 all phecode
771.1 Swelling of limb Symptoms 1.03 0.997 – 1.06 0.081 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 1.12 1.03 – 1.21 0.00772 659 6581 all phecode
773 Pain in limb Symptoms 1 0.974 – 1.03 0.995 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 0.896 0.765 – 1.05 0.177 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.01 0.966 – 1.06 0.605 1870 18715 all phecode
782.3 Edema Symptoms 1.02 0.967 – 1.07 0.508 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 1.01 0.866 – 1.17 0.946 175 1748 all phecode
783 Fever of unknown origin Symptoms 1.02 0.992 – 1.06 0.145 3911 39105 all phecode
785 Abdominal pain Symptoms 1 0.993 – 1.01 0.492 40080 301686 all phecode
788 Syncope and collapse Symptoms 1.01 0.988 – 1.03 0.37 9069 90813 all phecode
789 Nausea and vomiting Symptoms 1.01 0.986 – 1.02 0.588 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.04 0.884 – 1.23 0.611 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 1.14 0.916 – 1.41 0.245 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.02 0.993 – 1.05 0.149 6357 63635 all phecode
791 Gangrene Symptoms 1.02 0.936 – 1.12 0.628 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1.12 0.9 – 1.39 0.314 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.972 0.814 – 1.16 0.751 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 0.977 0.895 – 1.06 0.592 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.07 0.878 – 1.3 0.51 120 1198 all phecode
797 Shock Symptoms 0.889 0.76 – 1.04 0.144 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 0.818 0.673 – 0.994 0.0431 102 1020 all phecode
798 Malaise and fatigue Symptoms 1.02 0.985 – 1.06 0.268 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 0.96 0.881 – 1.05 0.343 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 0.998 0.973 – 1.02 0.843 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.984 0.937 – 1.03 0.501 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.891 0.762 – 1.04 0.147 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.01 0.967 – 1.06 0.638 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 0.963 0.894 – 1.04 0.316 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.02 0.973 – 1.06 0.461 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.01 0.962 – 1.06 0.705 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.99 0.917 – 1.07 0.79 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.998 0.975 – 1.02 0.831 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 0.991 0.943 – 1.04 0.73 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1 0.976 – 1.03 0.76 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.997 0.946 – 1.05 0.912 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 1 0.965 – 1.04 0.997 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.04 0.98 – 1.1 0.205 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 1.01 0.939 – 1.09 0.797 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.05 0.992 – 1.11 0.0922 1300 12998 all phecode
817 Concussion Injuries & Poisonings 1.02 0.895 – 1.16 0.78 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.01 0.922 – 1.1 0.86 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.03 0.992 – 1.07 0.121 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 0.99 0.942 – 1.04 0.696 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 0.991 0.948 – 1.04 0.689 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 0.994 0.978 – 1.01 0.486 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 0.974 0.891 – 1.06 0.566 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 1.02 0.931 – 1.12 0.647 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.03 0.998 – 1.06 0.0686 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.987 0.836 – 1.17 0.879 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.02 0.933 – 1.12 0.628 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.03 0.985 – 1.08 0.175 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.99 0.935 – 1.05 0.742 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.986 0.951 – 1.02 0.458 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1 0.969 – 1.04 0.803 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1.4 1.09 – 1.8 0.00796 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.04 1 – 1.08 0.0271 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.943 0.832 – 1.07 0.362 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 1.1 0.952 – 1.28 0.19 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.03 0.991 – 1.07 0.137 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.1 0.957 – 1.26 0.179 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 0.988 0.777 – 1.26 0.922 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.01 0.976 – 1.04 0.624 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.04 0.789 – 1.37 0.782 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.04 0.844 – 1.28 0.71 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.979 0.84 – 1.14 0.782 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 0.98 0.892 – 1.08 0.683 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 1.04 0.911 – 1.19 0.563 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.12 0.955 – 1.31 0.165 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 0.926 0.788 – 1.09 0.35 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 0.955 0.903 – 1.01 0.111 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.01 0.979 – 1.04 0.505 4260 42663 all phecode
916 Contusion Injuries & Poisonings 1.03 0.978 – 1.09 0.24 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.954 0.819 – 1.11 0.548 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.995 0.896 – 1.1 0.923 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.981 0.861 – 1.12 0.769 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.984 0.941 – 1.03 0.494 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.18 1.03 – 1.36 0.0188 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.883 0.722 – 1.08 0.227 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.05 0.967 – 1.15 0.23 550 5509 all phecode
947 Urticaria Injuries & Poisonings 1.01 0.903 – 1.12 0.917 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 1.1 0.994 – 1.23 0.0654 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.11 1 – 1.22 0.0479 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.926 0.817 – 1.05 0.224 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.01 0.919 – 1.1 0.883 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.17 0.888 – 1.53 0.269 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.924 0.736 – 1.16 0.495 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.01 0.993 – 1.02 0.298 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.01 0.995 – 1.03 0.164 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 0.988 0.894 – 1.09 0.81 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.01 0.941 – 1.08 0.794 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.06 0.956 – 1.18 0.26 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.08 0.972 – 1.2 0.148 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.995 0.867 – 1.14 0.941 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.04 0.92 – 1.17 0.54 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.03 0.906 – 1.16 0.689 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.993 0.967 – 1.02 0.577 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.03 0.971 – 1.1 0.313 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.02 0.925 – 1.12 0.739 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.922 0.834 – 1.02 0.116 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.04 0.955 – 1.14 0.339 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.989 0.908 – 1.08 0.795 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.03 0.984 – 1.08 0.199 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.955 0.824 – 1.11 0.542 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.04 0.921 – 1.18 0.513 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.914 0.738 – 1.13 0.41 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.06 0.87 – 1.3 0.554 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.2 0.982 – 1.47 0.0744 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.934 0.726 – 1.2 0.596 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.796 0.618 – 1.03 0.0795 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.2 1.04 – 1.37 0.0098 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.11 1.03 – 1.2 0.00606 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.957 0.829 – 1.11 0.552 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.05 0.801 – 1.38 0.719 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.04 0.856 – 1.26 0.693 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.963 0.793 – 1.17 0.703 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.12 0.888 – 1.4 0.348 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 0.984 0.949 – 1.02 0.401 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.01 0.969 – 1.04 0.763 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 1.01 0.969 – 1.04 0.763 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 0.993 0.972 – 1.02 0.553 8743 88089 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 0.987 0.948 – 1.03 0.511 2687 27082 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.972 0.896 – 1.05 0.5 639 6511 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.02 0.947 – 1.09 0.659 857 8585 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.44 1.1 – 1.9 0.0087 55 549 exclusion phecode
010 Tuberculosis Infectious Diseases 0.906 0.774 – 1.06 0.219 166 1654 exclusion phecode
038 Septicemia Infectious Diseases 1.02 0.992 – 1.06 0.14 4093 41660 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.05 0.982 – 1.13 0.146 839 8480 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1 0.915 – 1.1 0.94 490 4968 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1 0.983 – 1.02 0.875 11871 120031 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.01 0.971 – 1.04 0.701 3094 31292 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 0.983 0.934 – 1.03 0.504 1623 16398 exclusion phecode
041.4 E. coli Infectious Diseases 1.01 0.971 – 1.05 0.592 2663 27221 exclusion phecode
053 Herpes zoster Infectious Diseases 1.06 0.956 – 1.18 0.266 409 4116 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.21 0.976 – 1.49 0.0829 95 944 exclusion phecode
054 Herpes simplex Infectious Diseases 1.12 0.972 – 1.28 0.119 211 2098 exclusion phecode
070 Viral hepatitis Infectious Diseases 0.98 0.901 – 1.06 0.628 585 5903 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 0.924 0.71 – 1.2 0.555 68 686 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 1.02 0.855 – 1.22 0.822 132 1329 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 0.977 0.863 – 1.11 0.715 255 2564 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.09 0.96 – 1.24 0.183 274 2760 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 0.921 0.833 – 1.02 0.109 425 4274 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.84 0.714 – 0.989 0.036 147 1467 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.808 0.676 – 0.966 0.0195 117 1168 exclusion phecode
078 Viral warts & HPV Infectious Diseases 1.02 0.951 – 1.08 0.651 986 9999 exclusion phecode
079 Viral infection Infectious Diseases 1.02 0.982 – 1.06 0.288 2735 27598 exclusion phecode
079.1 Varicella infection Infectious Diseases 1.16 0.901 – 1.48 0.253 64 637 exclusion phecode
080 Postoperative infection Infectious Diseases 1.02 0.992 – 1.06 0.147 4395 44638 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.03 0.991 – 1.08 0.121 2437 24697 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.975 0.77 – 1.24 0.837 71 706 exclusion phecode
1000 Burns Injuries & Poisonings 1.03 0.947 – 1.13 0.467 576 5786 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 0.974 0.919 – 1.03 0.38 1195 11969 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.01 0.987 – 1.04 0.298 5446 54604 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 0.953 0.846 – 1.07 0.436 295 2982 exclusion phecode
1005 Other symptoms Injuries & Poisonings 0.966 0.915 – 1.02 0.21 1422 14383 exclusion phecode
1006 Crushing injury Injuries & Poisonings 0.925 0.813 – 1.05 0.231 256 2556 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 0.991 0.871 – 1.13 0.887 256 2550 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1 0.939 – 1.07 0.967 1006 10122 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 1.01 0.988 – 1.03 0.387 8454 84699 exclusion phecode
1010 Other tests Injuries & Poisonings 0.991 0.965 – 1.02 0.502 5891 59290 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.988 0.967 – 1.01 0.279 9072 91278 exclusion phecode
1012 Late effect Injuries & Poisonings 1.03 0.843 – 1.27 0.747 105 1053 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.01 0.901 – 1.13 0.869 313 3162 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.1 0.855 – 1.41 0.467 66 658 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 1.02 0.984 – 1.05 0.329 4155 42145 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1 0.984 – 1.02 0.946 15777 158468 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.03 0.908 – 1.17 0.649 277 2804 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 1.02 0.898 – 1.16 0.764 271 2745 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.874 0.688 – 1.11 0.271 74 754 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.04 0.876 – 1.24 0.637 140 1408 exclusion phecode
112 Candidiasis Infectious Diseases 0.982 0.938 – 1.03 0.417 2080 21202 exclusion phecode
117 Mycoses Infectious Diseases 1.02 0.898 – 1.15 0.791 270 2713 exclusion phecode
117.4 Aspergillosis Infectious Diseases 0.994 0.848 – 1.16 0.936 164 1648 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.919 0.734 – 1.15 0.463 80 798 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 0.791 0.625 – 1 0.051 69 689 exclusion phecode
134 Helminthiases Infectious Diseases 1 0.836 – 1.21 0.966 127 1264 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.04 0.846 – 1.27 0.726 106 1057 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.01 0.878 – 1.17 0.858 202 2045 exclusion phecode
145 Cancer of mouth Neoplasms 0.968 0.892 – 1.05 0.435 640 6405 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.03 0.917 – 1.16 0.609 310 3094 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 1.18 0.961 – 1.45 0.114 105 1047 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 0.871 0.676 – 1.12 0.286 54 538 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.972 0.897 – 1.05 0.489 633 6337 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 0.921 0.812 – 1.05 0.204 252 2515 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.02 0.902 – 1.16 0.725 264 2640 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.1 0.836 – 1.45 0.495 57 570 exclusion phecode
150 Cancer of esophagus Neoplasms 1.04 0.967 – 1.12 0.29 760 7614 exclusion phecode
151 Cancer of stomach Neoplasms 1.01 0.929 – 1.1 0.792 566 5686 exclusion phecode
153 Colorectal cancer Neoplasms 0.982 0.953 – 1.01 0.251 4524 45670 exclusion phecode
153.2 Colon cancer Neoplasms 0.977 0.942 – 1.01 0.212 3069 30960 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.993 0.95 – 1.04 0.751 2136 21579 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.856 0.772 – 0.948 0.00289 395 4002 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.835 0.706 – 0.988 0.0352 157 1578 exclusion phecode
157 Pancreatic cancer Neoplasms 0.96 0.887 – 1.04 0.314 657 6563 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.01 0.952 – 1.08 0.674 1050 10608 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.994 0.967 – 1.02 0.66 5420 55555 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.01 0.866 – 1.18 0.91 188 1894 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.905 0.789 – 1.04 0.153 203 2045 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.15 0.94 – 1.41 0.176 99 1920 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.882 0.684 – 1.14 0.334 60 599 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.05 1.01 – 1.09 0.0176 2802 28148 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.04 0.997 – 1.09 0.0688 2210 22234 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 1.04 0.945 – 1.15 0.412 428 4353 exclusion phecode
170.1 Bone cancer Neoplasms 1.08 0.907 – 1.29 0.382 130 1307 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1.04 0.926 – 1.16 0.534 323 3293 exclusion phecode
172 Skin cancer Neoplasms 1.02 1 – 1.04 0.0198 13421 134485 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.07 1.03 – 1.11 0.00134 2669 26690 exclusion phecode
172.11 Melanomas of skin Neoplasms 1.07 1.03 – 1.12 0.000595 2701 27007 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1.02 0.999 – 1.04 0.064 10942 109648 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.916 0.845 – 0.993 0.0333 657 6634 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.15 0.991 – 1.35 0.0655 181 1814 exclusion phecode
174 Breast cancer Neoplasms 1.02 1 – 1.04 0.0149 12565 126597 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1.02 1.01 – 1.04 0.0104 12355 124506 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.02 1 – 1.04 0.0287 11637 117502 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.09 0.904 – 1.32 0.366 114 1148 exclusion phecode
175 Acquired absence of breast Neoplasms 1.06 1.01 – 1.1 0.00925 2361 24010 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.02 0.973 – 1.07 0.429 2107 21747 exclusion phecode
180.1 Cervical cancer Neoplasms 1.02 0.891 – 1.16 0.784 249 2720 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.02 0.976 – 1.07 0.356 2032 20784 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 1.08 1.02 – 1.15 0.0122 1203 12836 exclusion phecode
185 Cancer of prostate Neoplasms 0.961 0.936 – 0.986 0.00291 5974 58812 exclusion phecode
187 Cancer of other male genital organs Neoplasms 0.889 0.81 – 0.977 0.0142 449 4485 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.852 0.679 – 1.07 0.169 70 700 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.909 0.81 – 1.02 0.103 287 2868 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.03 0.849 – 1.25 0.76 110 1098 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.03 1 – 1.07 0.0349 4139 41511 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.05 0.982 – 1.11 0.167 1069 10695 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.03 0.966 – 1.1 0.369 1029 10296 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.22 0.961 – 1.55 0.103 66 660 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.03 0.985 – 1.07 0.216 2398 24060 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.03 0.981 – 1.07 0.267 2132 21399 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.05 0.88 – 1.24 0.616 143 1436 exclusion phecode
190 Cancer of eye Neoplasms 1.13 0.965 – 1.32 0.129 175 1748 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.19 1.1 – 1.29 1.76e-05 689 6861 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 1.2 1.1 – 1.31 4.51e-05 566 5634 exclusion phecode
191.11 Cancer of brain Neoplasms 1.2 1.1 – 1.31 6.23e-05 525 5225 exclusion phecode
193 Thyroid cancer Neoplasms 1.07 0.959 – 1.2 0.218 345 3451 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.18 0.949 – 1.46 0.137 94 946 exclusion phecode
195 Cancer, suspected or other Neoplasms 0.999 0.983 – 1.02 0.909 16370 165276 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1 0.985 – 1.02 0.837 15670 159314 exclusion phecode
197 Chemotherapy Neoplasms 1 0.99 – 1.02 0.601 20753 212909 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1 0.978 – 1.02 0.975 9005 95385 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.995 0.967 – 1.02 0.73 5184 53596 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1 0.957 – 1.05 0.981 2138 22644 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.941 0.886 – 1 0.051 1123 15473 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.02 0.975 – 1.06 0.463 2528 26609 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.02 0.948 – 1.09 0.627 812 8466 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 0.997 0.953 – 1.04 0.888 2111 21577 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.05 0.9 – 1.23 0.53 180 1888 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.01 0.955 – 1.06 0.758 1420 14298 exclusion phecode
199.4 Neurofibromatosis Neoplasms 0.982 0.796 – 1.21 0.862 92 948 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.2 1.13 – 1.29 2.62e-08 986 9884 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.23 1.11 – 1.37 9.46e-05 387 3859 exclusion phecode
201 Hodgkin's disease Neoplasms 0.928 0.817 – 1.05 0.247 259 2592 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.02 0.974 – 1.06 0.444 2256 22649 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.02 0.968 – 1.07 0.529 1797 18022 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.07 0.96 – 1.19 0.223 363 3630 exclusion phecode
202.24 Large cell lymphoma Neoplasms 0.988 0.907 – 1.08 0.783 579 5810 exclusion phecode
204 Leukemia Neoplasms 1.04 0.99 – 1.09 0.118 1652 16579 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 0.999 0.918 – 1.09 0.991 574 5767 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.09 0.826 – 1.43 0.553 56 559 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.993 0.907 – 1.09 0.872 504 5069 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.11 1.01 – 1.23 0.0251 458 4602 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 1.14 1.01 – 1.27 0.0271 327 3280 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.985 0.832 – 1.17 0.859 142 1435 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.06 0.97 – 1.16 0.203 555 5543 exclusion phecode
208 Benign neoplasm of colon Neoplasms 0.993 0.978 – 1.01 0.339 19766 191332 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.991 0.929 – 1.06 0.784 976 9751 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1 0.976 – 1.03 0.751 5213 52251 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.922 0.826 – 1.03 0.142 347 3455 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.936 0.836 – 1.05 0.256 316 3175 exclusion phecode
214 Lipoma Neoplasms 1.03 1.01 – 1.06 0.0133 6213 62165 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.04 1.01 – 1.07 0.0178 4572 45716 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.07 1.01 – 1.14 0.0253 1103 11018 exclusion phecode
216 Benign neoplasm of skin Neoplasms 1.02 1 – 1.05 0.0532 7631 76365 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.968 0.891 – 1.05 0.434 627 6286 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.98 0.9 – 1.07 0.638 589 5914 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 1.07 1.05 – 1.1 5.31e-11 9817 100200 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 1.08 1.05 – 1.1 3.64e-12 10042 102376 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.1 0.984 – 1.23 0.0937 342 3548 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 1.08 1.02 – 1.14 0.00461 1396 14483 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.11 0.963 – 1.29 0.146 208 2196 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.942 0.802 – 1.11 0.463 160 1600 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.08 0.919 – 1.26 0.362 171 1728 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.936 0.785 – 1.12 0.467 129 1294 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.803 0.631 – 1.02 0.0757 67 676 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.14 1.06 – 1.22 0.000675 808 8120 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.14 1.06 – 1.23 0.000684 767 7726 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.03 0.792 – 1.35 0.81 59 584 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.09 0.955 – 1.24 0.21 262 2651 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.994 0.927 – 1.07 0.867 858 8597 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.943 0.812 – 1.1 0.441 184 1852 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.992 0.892 – 1.1 0.889 371 3689 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.01 0.902 – 1.14 0.816 308 3104 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.08 1.02 – 1.13 0.0047 1588 15912 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.04 1 – 1.09 0.049 2385 23851 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.02 0.94 – 1.12 0.581 595 5983 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.04 0.976 – 1.1 0.233 1100 11040 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.01 0.92 – 1.11 0.814 469 4687 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.05 0.972 – 1.14 0.212 671 6751 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.02 0.974 – 1.07 0.366 1839 18439 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 1.07 0.974 – 1.19 0.152 452 4536 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 0.705 0.568 – 0.875 0.0015 89 904 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 1.11 0.935 – 1.33 0.227 138 1374 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.01 0.992 – 1.03 0.275 14439 144247 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.04 0.973 – 1.1 0.266 1091 11030 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.908 0.743 – 1.11 0.346 101 1004 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.01 0.992 – 1.03 0.266 13776 138151 exclusion phecode
245 Thyroiditis Endocrine/metabolic 1.01 0.892 – 1.14 0.915 286 2860 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.14 0.988 – 1.31 0.0721 217 2164 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.14 0.988 – 1.32 0.0724 209 2084 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.06 0.951 – 1.18 0.301 395 3953 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1 0.99 – 1.02 0.548 19696 185490 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1 0.962 – 1.04 0.969 2743 27550 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.07 0.938 – 1.23 0.301 238 2380 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.13 0.897 – 1.43 0.294 76 770 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.03 0.934 – 1.13 0.595 471 4735 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.12 0.958 – 1.31 0.154 160 1604 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1 0.985 – 1.02 0.962 17746 169732 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.967 0.793 – 1.18 0.737 103 1042 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.06 0.914 – 1.22 0.461 200 2014 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.06 0.99 – 1.13 0.0958 983 9880 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.04 0.948 – 1.13 0.431 501 5058 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 0.959 0.886 – 1.04 0.304 678 6810 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.913 0.805 – 1.04 0.16 265 2651 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1 0.904 – 1.11 0.993 414 4168 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.03 0.859 – 1.23 0.773 131 1307 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.06 0.957 – 1.18 0.249 348 3489 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.05 0.995 – 1.11 0.0714 1325 13307 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1 0.936 – 1.07 0.978 931 9355 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.984 0.916 – 1.06 0.649 867 8666 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.991 0.92 – 1.07 0.816 777 7756 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.82 0.687 – 0.978 0.0269 140 1413 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.992 0.917 – 1.07 0.838 680 6787 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.994 0.858 – 1.15 0.939 186 1859 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.981 0.794 – 1.21 0.855 94 944 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.959 0.845 – 1.09 0.522 260 2609 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.02 0.832 – 1.26 0.828 92 916 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.03 0.881 – 1.21 0.682 158 1568 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.05 0.968 – 1.14 0.241 634 6353 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.99 0.85 – 1.15 0.894 180 1791 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.02 0.84 – 1.25 0.813 103 1023 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.964 0.762 – 1.22 0.759 76 758 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.06 0.951 – 1.18 0.293 359 3605 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.07 0.957 – 1.19 0.244 358 3595 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 1.05 0.915 – 1.2 0.511 236 2387 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.05 0.906 – 1.21 0.541 205 2081 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 0.96 0.818 – 1.13 0.618 160 1619 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.967 0.821 – 1.14 0.69 152 1539 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.09 0.891 – 1.34 0.397 101 1016 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 1.14 0.967 – 1.34 0.118 149 1493 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.08 0.939 – 1.25 0.272 197 2010 exclusion phecode
260.1 Cachexia Endocrine/metabolic 0.787 0.595 – 1.04 0.0953 51 510 exclusion phecode
260.6 Anorexia Endocrine/metabolic 0.976 0.909 – 1.05 0.507 822 8281 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.02 0.959 – 1.08 0.564 1183 11921 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1 0.932 – 1.08 0.927 749 7510 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.01 0.916 – 1.12 0.812 437 4437 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.853 0.674 – 1.08 0.185 71 763 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.914 0.801 – 1.04 0.179 239 2399 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.09 0.978 – 1.22 0.115 337 3376 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.24 1.1 – 1.4 0.000431 302 3023 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.21 1.06 – 1.38 0.00379 260 2605 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.2 1.03 – 1.39 0.0202 191 1907 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 0.916 0.762 – 1.1 0.348 112 1122 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.26 0.993 – 1.61 0.057 68 688 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.08 0.921 – 1.28 0.331 156 1591 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.11 0.933 – 1.33 0.232 135 1386 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.993 0.982 – 1 0.258 34679 234658 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.993 0.982 – 1 0.235 34608 234432 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.992 0.981 – 1 0.185 32170 227335 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.843 0.645 – 1.1 0.212 58 580 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.07 0.915 – 1.26 0.384 164 1635 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.979 0.851 – 1.13 0.77 210 2105 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.03 0.993 – 1.06 0.124 3716 37179 exclusion phecode
274.1 Gout Endocrine/metabolic 1.04 1 – 1.08 0.0475 3166 31669 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.02 0.846 – 1.24 0.822 112 1119 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.97 0.894 – 1.05 0.469 610 6107 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.974 0.894 – 1.06 0.55 556 5563 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.01 0.962 – 1.05 0.793 2068 21011 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 1.03 0.955 – 1.12 0.411 650 6522 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 0.956 0.86 – 1.06 0.414 353 3733 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.988 0.931 – 1.05 0.696 1184 11987 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.03 0.882 – 1.21 0.698 169 1714 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.01 0.983 – 1.03 0.577 7130 72727 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.02 0.992 – 1.06 0.143 3998 40806 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.06 0.927 – 1.2 0.411 237 2405 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.05 1 – 1.11 0.0389 1775 18143 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 0.994 0.93 – 1.06 0.871 945 9713 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.04 0.98 – 1.09 0.214 1395 14183 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.02 0.961 – 1.09 0.491 1147 11597 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.02 0.96 – 1.09 0.49 1043 10549 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.05 0.872 – 1.26 0.609 112 1125 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 0.967 0.93 – 1.01 0.0956 2747 28191 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.07 0.97 – 1.18 0.177 446 4532 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.01 0.839 – 1.21 0.948 127 1273 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.01 0.945 – 1.08 0.741 883 8945 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.976 0.877 – 1.09 0.663 361 3603 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.945 0.826 – 1.08 0.405 229 2295 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.703 0.541 – 0.913 0.00821 52 519 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.02 1 – 1.04 0.051 10746 107897 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.02 1 – 1.04 0.0542 10584 106281 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 0.961 0.768 – 1.2 0.728 84 834 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.08 0.837 – 1.39 0.554 65 659 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.958 0.841 – 1.09 0.517 248 2502 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 0.941 0.816 – 1.09 0.406 208 2093 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.895 0.751 – 1.07 0.213 138 1382 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.03 0.905 – 1.17 0.659 248 2476 exclusion phecode
280 Iron deficiency anemias Hematopoietic 0.999 0.976 – 1.02 0.95 7559 75913 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.998 0.974 – 1.02 0.858 7266 72905 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.03 0.939 – 1.14 0.493 444 4530 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.02 0.956 – 1.08 0.602 1102 11095 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1 0.943 – 1.07 0.897 1056 10639 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.02 0.948 – 1.1 0.562 742 7487 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.996 0.857 – 1.16 0.962 176 1765 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 0.928 0.802 – 1.07 0.31 181 1836 exclusion phecode
281.9 Deficiency anemias Hematopoietic 0.969 0.736 – 1.28 0.824 54 536 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 0.939 0.796 – 1.11 0.457 149 1490 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 0.945 0.723 – 1.24 0.68 55 557 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.899 0.722 – 1.12 0.34 84 845 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.16 0.967 – 1.38 0.112 133 1374 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.06 0.87 – 1.3 0.555 101 1056 exclusion phecode
284 Aplastic anemia Hematopoietic 1.02 0.923 – 1.13 0.702 427 4340 exclusion phecode
285 Other anemias Hematopoietic 1 0.983 – 1.02 0.843 11856 120730 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.03 0.906 – 1.17 0.664 270 2697 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.04 0.962 – 1.13 0.316 657 6958 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.04 0.931 – 1.15 0.522 375 4136 exclusion phecode
286 Coagulation defects Hematopoietic 1.05 0.98 – 1.12 0.168 914 9184 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.996 0.905 – 1.1 0.933 455 4571 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.972 0.788 – 1.2 0.79 94 953 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.984 0.873 – 1.11 0.792 293 2931 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 0.991 0.772 – 1.27 0.946 62 628 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.91 0.724 – 1.14 0.42 86 860 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.13 1.02 – 1.25 0.0243 383 3852 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.02 0.973 – 1.08 0.376 1623 16479 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.08 0.903 – 1.3 0.387 129 1285 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.02 0.969 – 1.08 0.445 1524 15496 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.12 1.01 – 1.23 0.028 417 4180 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.06 0.831 – 1.34 0.658 72 748 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.04 1 – 1.07 0.036 3640 37541 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.04 1 – 1.08 0.0382 3058 31597 exclusion phecode
288.11 Neutropenia Hematopoietic 1.04 1 – 1.08 0.0358 3066 31677 exclusion phecode
288.3 Eosinophilia Hematopoietic 1.13 0.887 – 1.45 0.318 70 705 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.04 0.968 – 1.11 0.296 857 8589 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.1 0.979 – 1.25 0.106 289 2887 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.02 0.98 – 1.06 0.316 2564 25985 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1.09 0.995 – 1.2 0.0643 507 5142 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.09 0.968 – 1.22 0.157 292 2914 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 0.946 0.762 – 1.17 0.613 87 898 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.945 0.902 – 0.99 0.0177 1920 19215 exclusion phecode
290.1 Dementias Mental Disorders 0.924 0.866 – 0.986 0.0164 999 9999 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.854 0.773 – 0.943 0.00181 428 4291 exclusion phecode
290.16 Vascular dementia Mental Disorders 0.961 0.833 – 1.11 0.588 200 2005 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.934 0.862 – 1.01 0.0955 646 6482 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.08 0.85 – 1.37 0.529 70 708 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.01 0.945 – 1.09 0.686 831 8366 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.01 0.85 – 1.21 0.877 130 1313 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.991 0.877 – 1.12 0.886 286 2861 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.04 0.943 – 1.15 0.43 433 4367 exclusion phecode
292 Neurological disorders Mental Disorders 0.991 0.962 – 1.02 0.569 4586 46135 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.01 0.956 – 1.06 0.794 1497 15042 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 1.02 0.879 – 1.19 0.768 190 1900 exclusion phecode
292.3 Memory loss Mental Disorders 0.955 0.884 – 1.03 0.246 693 6966 exclusion phecode
292.4 Altered mental status Mental Disorders 1 0.96 – 1.05 0.895 2159 21761 exclusion phecode
292.6 Hallucinations Mental Disorders 0.941 0.84 – 1.06 0.3 302 3063 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 0.968 0.926 – 1.01 0.158 2074 20744 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.06 0.987 – 1.13 0.113 898 8972 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.964 0.898 – 1.03 0.313 837 8430 exclusion phecode
295.1 Schizophrenia Mental Disorders 0.967 0.889 – 1.05 0.443 572 5760 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.07 0.917 – 1.25 0.398 176 1774 exclusion phecode
295.3 Psychosis Mental Disorders 1.01 0.866 – 1.19 0.861 168 1705 exclusion phecode
296 Mood disorders Mental Disorders 1.01 0.989 – 1.03 0.428 12280 123402 exclusion phecode
296.1 Bipolar Mental Disorders 0.987 0.927 – 1.05 0.695 1053 10564 exclusion phecode
296.2 Depression Mental Disorders 1.01 0.991 – 1.03 0.289 11650 117070 exclusion phecode
296.22 Major depressive disorder Mental Disorders 0.933 0.838 – 1.04 0.206 359 3591 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.991 0.884 – 1.11 0.878 311 3066 exclusion phecode
300 Anxiety disorders Mental Disorders 0.999 0.974 – 1.02 0.927 6796 68244 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1 0.975 – 1.03 0.934 6280 63054 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 0.88 0.746 – 1.04 0.131 149 1495 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.02 0.947 – 1.11 0.567 701 7053 exclusion phecode
300.13 Phobia Mental Disorders 1.02 0.933 – 1.12 0.644 498 4988 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.05 0.881 – 1.25 0.597 138 1403 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.26 0.956 – 1.67 0.1 53 527 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 0.972 0.814 – 1.16 0.752 123 1232 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.97 0.804 – 1.17 0.747 113 1126 exclusion phecode
301 Personality disorders Mental Disorders 0.986 0.884 – 1.1 0.809 332 3332 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.959 0.794 – 1.16 0.665 118 1183 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 0.899 0.8 – 1.01 0.074 283 2845 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.961 0.873 – 1.06 0.41 463 4662 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.962 0.862 – 1.07 0.483 347 3502 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.936 0.782 – 1.12 0.469 122 1221 exclusion phecode
304 Adjustment reaction Mental Disorders 1.05 0.932 – 1.18 0.421 293 2928 exclusion phecode
305.2 Eating disorder Mental Disorders 1.1 0.881 – 1.39 0.389 90 895 exclusion phecode
306 Other mental disorder Mental Disorders 1.01 0.995 – 1.02 0.26 27885 229389 exclusion phecode
306.9 Tension headache Mental Disorders 0.97 0.862 – 1.09 0.617 312 3142 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.867 0.689 – 1.09 0.223 75 770 exclusion phecode
313.3 Autism Mental Disorders 0.944 0.71 – 1.26 0.693 52 538 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.04 0.928 – 1.16 0.533 347 3502 exclusion phecode
315.1 Learning disorder Mental Disorders 0.982 0.834 – 1.16 0.827 160 1608 exclusion phecode
315.2 Speech and language disorder Mental Disorders 1.14 0.91 – 1.43 0.256 87 877 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.01 0.978 – 1.03 0.66 5299 53060 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.871 0.662 – 1.15 0.322 55 597 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1 0.984 – 1.02 0.853 12655 126644 exclusion phecode
317.1 Alcoholism Mental Disorders 0.998 0.977 – 1.02 0.848 8858 88737 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 0.923 0.86 – 0.99 0.0249 835 8379 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.01 0.991 – 1.02 0.462 19253 185022 exclusion phecode
320 Meningitis Neurological 0.934 0.848 – 1.03 0.17 444 4437 exclusion phecode
323 Encephalitis Neurological 1.04 0.931 – 1.16 0.481 339 3413 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 1.1 0.862 – 1.39 0.456 73 738 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 0.936 0.834 – 1.05 0.262 292 2910 exclusion phecode
327 Sleep disorders Neurological 1.01 0.949 – 1.07 0.81 1159 11630 exclusion phecode
327.3 Sleep apnea Neurological 0.985 0.955 – 1.02 0.318 4420 44237 exclusion phecode
327.4 Insomnia Neurological 1.12 0.952 – 1.32 0.172 161 1650 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.22 1.02 – 1.46 0.0293 134 1380 exclusion phecode
331 Other cerebral degenerations Neurological 0.987 0.928 – 1.05 0.663 1133 11387 exclusion phecode
331.1 Hydrocephalus Neurological 1.04 0.951 – 1.15 0.364 497 4999 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 0.979 0.887 – 1.08 0.678 428 4291 exclusion phecode
332 Parkinson's disease Neurological 0.975 0.917 – 1.04 0.415 1123 11220 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.01 0.94 – 1.08 0.836 887 8929 exclusion phecode
333.1 Essential tremor Neurological 0.983 0.856 – 1.13 0.81 215 2154 exclusion phecode
333.2 Myoclonus Neurological 0.974 0.792 – 1.2 0.804 95 956 exclusion phecode
333.4 Torsion dystonia Neurological 1.02 0.898 – 1.16 0.744 250 2516 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.01 0.962 – 1.06 0.718 1801 18094 exclusion phecode
334.1 Spinocerebellar disease Neurological 0.987 0.812 – 1.2 0.893 115 1164 exclusion phecode
334.2 Anterior horn cell disease Neurological 1.06 0.935 – 1.21 0.346 245 2441 exclusion phecode
335 Multiple sclerosis Neurological 0.966 0.913 – 1.02 0.236 1334 13331 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 0.994 0.875 – 1.13 0.928 265 2661 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 0.847 0.67 – 1.07 0.164 72 718 exclusion phecode
338 Pain Neurological 1.08 1 – 1.16 0.0414 765 7671 exclusion phecode
338.1 Acute pain Neurological 1.08 0.97 – 1.19 0.163 392 3924 exclusion phecode
338.2 Chronic pain Neurological 1.08 0.968 – 1.2 0.174 379 3808 exclusion phecode
339 Other headache syndromes Neurological 1.01 0.988 – 1.03 0.359 7760 77957 exclusion phecode
340 Migraine Neurological 1.03 0.992 – 1.07 0.122 2837 28482 exclusion phecode
340.1 Migrain with aura Neurological 0.925 0.805 – 1.06 0.27 212 2108 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.997 0.878 – 1.13 0.959 250 2525 exclusion phecode
342 Hemiplegia Neurological 1.04 0.985 – 1.1 0.158 1484 14915 exclusion phecode
343 Infantile cerebral palsy Neurological 0.958 0.81 – 1.13 0.615 145 1448 exclusion phecode
344 Other paralytic syndromes Neurological 0.979 0.903 – 1.06 0.601 654 6574 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1 0.972 – 1.03 0.976 4990 50142 exclusion phecode
345.1 Epilepsy Neurological 0.942 0.878 – 1.01 0.0975 861 8633 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 0.95 0.862 – 1.05 0.304 437 4369 exclusion phecode
345.12 Partial epilepsy Neurological 0.892 0.787 – 1.01 0.0716 276 2770 exclusion phecode
345.3 Convulsions Neurological 0.972 0.931 – 1.02 0.207 2219 22288 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.23 1.04 – 1.47 0.0178 139 1430 exclusion phecode
348 Other conditions of brain Neurological 0.989 0.919 – 1.06 0.771 772 7788 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 0.993 0.875 – 1.13 0.917 265 2669 exclusion phecode
348.4 Cerebral cysts Neurological 1.07 0.893 – 1.28 0.465 132 1346 exclusion phecode
348.7 Coma Neurological 1.02 0.919 – 1.14 0.663 356 3586 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.02 0.897 – 1.16 0.764 247 2499 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.07 0.967 – 1.19 0.184 386 3887 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.966 0.862 – 1.08 0.546 337 3403 exclusion phecode
350 Abnormal movement Neurological 0.989 0.95 – 1.03 0.586 2645 26637 exclusion phecode
350.1 Abnormal involuntary movements Neurological 0.916 0.855 – 0.982 0.014 881 8823 exclusion phecode
350.2 Abnormality of gait Neurological 1.01 0.958 – 1.06 0.733 1577 15919 exclusion phecode
350.3 Lack of coordination Neurological 1.04 0.933 – 1.16 0.474 362 3630 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.927 0.701 – 1.23 0.594 53 539 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.01 0.989 – 1.03 0.455 12366 123773 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.03 0.977 – 1.09 0.261 1359 13656 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.09 0.99 – 1.2 0.0805 459 4622 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.02 0.953 – 1.1 0.538 873 8761 exclusion phecode
353 Nerve root and plexus disorders Neurological 0.998 0.939 – 1.06 0.943 1123 11278 exclusion phecode
353.1 Nerve plexus lesions Neurological 1.04 0.858 – 1.26 0.686 113 1138 exclusion phecode
353.2 Nerve root lesions Neurological 1.07 0.798 – 1.42 0.668 56 566 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.993 0.843 – 1.17 0.938 151 1517 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.02 0.966 – 1.08 0.462 1350 13615 exclusion phecode
358 Myoneural disorders Neurological 0.99 0.858 – 1.14 0.891 211 2099 exclusion phecode
358.1 Myasthenia gravis Neurological 0.991 0.852 – 1.15 0.902 192 1911 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 1.04 0.942 – 1.14 0.467 461 4634 exclusion phecode
359.1 Muscular dystrophies Neurological 0.889 0.738 – 1.07 0.212 121 1217 exclusion phecode
359.2 Myopathy Neurological 1.09 0.977 – 1.21 0.125 357 3588 exclusion phecode
360 Disorders of the globe Sense Organs 0.938 0.842 – 1.05 0.246 337 3353 exclusion phecode
360.2 Progressive myopia Sense Organs 0.893 0.788 – 1.01 0.078 251 2499 exclusion phecode
361 Retinal detachments and defects Sense Organs 1.03 0.989 – 1.06 0.172 3236 32363 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.01 0.956 – 1.07 0.699 1387 13847 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.979 0.774 – 1.24 0.863 68 678 exclusion phecode
362 Other retinal disorders Sense Organs 0.985 0.953 – 1.02 0.362 3816 38220 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.01 0.967 – 1.06 0.628 2163 21702 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.01 0.967 – 1.06 0.631 2160 21672 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.02 0.864 – 1.19 0.85 161 1605 exclusion phecode
362.31 Separation of retinal layers Sense Organs 0.956 0.78 – 1.17 0.668 99 986 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.968 0.903 – 1.04 0.367 847 8452 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 1.08 0.926 – 1.26 0.32 182 1821 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.979 0.781 – 1.23 0.851 81 810 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.897 0.746 – 1.08 0.247 116 1153 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.945 0.804 – 1.11 0.496 168 1694 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.811 0.633 – 1.04 0.0976 69 688 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.955 0.882 – 1.03 0.263 644 6458 exclusion phecode
364.1 Corneal opacity Sense Organs 0.927 0.749 – 1.15 0.49 90 908 exclusion phecode
364.2 Corneal edema Sense Organs 0.85 0.684 – 1.06 0.146 79 798 exclusion phecode
364.4 Corneal degenerations Sense Organs 1.05 0.907 – 1.21 0.519 200 2009 exclusion phecode
364.41 Keratoconus Sense Organs 0.904 0.729 – 1.12 0.358 86 868 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.892 0.776 – 1.03 0.11 210 2101 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.997 0.81 – 1.23 0.978 100 998 exclusion phecode
365 Glaucoma Sense Organs 1.01 0.978 – 1.04 0.587 4380 43962 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 0.99 0.929 – 1.06 0.763 1022 10313 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.984 0.923 – 1.05 0.627 1016 10252 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.971 0.898 – 1.05 0.465 696 6965 exclusion phecode
366 Cataract Sense Organs 0.992 0.978 – 1.01 0.305 19835 168058 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 1.16 0.914 – 1.46 0.225 69 697 exclusion phecode
366.2 Senile cataract Sense Organs 0.994 0.972 – 1.02 0.613 8192 81550 exclusion phecode
366.3 Traumatic cataract Sense Organs 1.12 0.918 – 1.37 0.263 102 1017 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.972 0.932 – 1.01 0.185 2396 24003 exclusion phecode
367.1 Myopia Sense Organs 0.973 0.918 – 1.03 0.358 1244 12459 exclusion phecode
367.2 Astigmatism Sense Organs 0.829 0.717 – 0.959 0.0114 190 1889 exclusion phecode
367.8 Hypermetropia Sense Organs 0.998 0.876 – 1.14 0.978 252 2521 exclusion phecode
367.9 Blindness and low vision Sense Organs 0.983 0.912 – 1.06 0.667 716 7180 exclusion phecode
368 Visual disturbances Sense Organs 0.995 0.958 – 1.03 0.78 2945 29533 exclusion phecode
368.1 Amblyopia Sense Organs 0.99 0.905 – 1.08 0.827 531 5296 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.02 0.944 – 1.1 0.631 723 7268 exclusion phecode
368.3 Anisometropia Sense Organs 0.898 0.763 – 1.06 0.2 154 1546 exclusion phecode
368.4 Visual field defects Sense Organs 0.963 0.86 – 1.08 0.507 330 3311 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.998 0.92 – 1.08 0.953 608 6090 exclusion phecode
369 Infection of the eye Sense Organs 1.07 0.979 – 1.17 0.136 549 5520 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.96 0.803 – 1.15 0.653 124 1249 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 1.15 0.995 – 1.33 0.0592 211 2121 exclusion phecode
370 Keratitis Sense Organs 1.06 0.94 – 1.2 0.329 285 2844 exclusion phecode
370.1 Corneal ulcer Sense Organs 1.05 0.884 – 1.25 0.569 140 1403 exclusion phecode
371 Inflammation of the eye Sense Organs 0.993 0.957 – 1.03 0.725 3035 30384 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.946 0.863 – 1.04 0.235 480 4808 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 1.01 0.965 – 1.05 0.766 2346 23464 exclusion phecode
372 Disorders of conjunctiva Sense Organs 0.99 0.918 – 1.07 0.79 758 7572 exclusion phecode
374 Other disorders of eyelids Sense Organs 1.01 0.978 – 1.03 0.701 5653 56595 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.983 0.923 – 1.05 0.582 1057 10609 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.999 0.953 – 1.05 0.984 1818 18152 exclusion phecode
375 Disorders of lacrimal system Sense Organs 1.01 0.963 – 1.05 0.779 2193 21911 exclusion phecode
375.2 Epiphora Sense Organs 1.04 0.974 – 1.12 0.223 894 8928 exclusion phecode
376 Disorders of the orbit Sense Organs 0.873 0.7 – 1.09 0.226 86 856 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.06 0.955 – 1.19 0.256 359 3604 exclusion phecode
377.1 Optic atrophy Sense Organs 1.11 0.846 – 1.45 0.459 56 566 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.08 0.902 – 1.29 0.407 123 1244 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.01 0.953 – 1.06 0.819 1406 14079 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1 0.939 – 1.08 0.887 907 9060 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.92 0.801 – 1.06 0.235 213 2137 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.03 0.91 – 1.17 0.634 274 2749 exclusion phecode
379 Other disorders of eye Sense Organs 0.99 0.957 – 1.02 0.546 3691 36916 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.997 0.943 – 1.05 0.92 1363 13609 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.974 0.929 – 1.02 0.281 1808 18059 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 0.888 0.694 – 1.14 0.344 71 709 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1 0.903 – 1.11 0.978 399 4022 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.03 0.882 – 1.21 0.688 167 1688 exclusion phecode
380 Disorders of external ear Sense Organs 1.02 0.939 – 1.1 0.656 640 6389 exclusion phecode
380.1 Otitis externa Sense Organs 0.943 0.862 – 1.03 0.197 507 5088 exclusion phecode
380.4 Impacted cerumen Sense Organs 1.01 0.904 – 1.12 0.897 360 3599 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.983 0.94 – 1.03 0.44 2137 21421 exclusion phecode
381.1 Otitis media Sense Organs 0.983 0.937 – 1.03 0.496 1757 17615 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.964 0.898 – 1.04 0.319 849 8499 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.942 0.814 – 1.09 0.418 190 1923 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.953 0.815 – 1.11 0.542 171 1705 exclusion phecode
381.9 Otorrhea Sense Organs 0.949 0.839 – 1.07 0.408 279 2797 exclusion phecode
382 Otalgia Sense Organs 1.1 0.979 – 1.24 0.109 305 3071 exclusion phecode
383 Otosclerosis Sense Organs 0.999 0.891 – 1.12 0.985 308 3078 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.03 0.974 – 1.09 0.294 1294 12947 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.04 0.972 – 1.11 0.276 1040 10394 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.05 0.974 – 1.13 0.21 779 7812 exclusion phecode
385.3 Cholesteatoma Sense Organs 1.01 0.931 – 1.1 0.78 603 6061 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.14 0.999 – 1.31 0.0512 241 2395 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.996 0.948 – 1.05 0.874 1725 17310 exclusion phecode
386.1 Meniere's disease Sense Organs 0.949 0.871 – 1.03 0.229 572 5741 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 1.01 0.909 – 1.12 0.847 374 3753 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.01 0.934 – 1.08 0.884 760 7635 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.02 0.985 – 1.05 0.327 4556 45668 exclusion phecode
388 Other disorders of ear Sense Organs 1.01 0.878 – 1.17 0.863 201 2008 exclusion phecode
389 Hearing loss Sense Organs 0.997 0.965 – 1.03 0.832 4156 41810 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.947 0.862 – 1.04 0.262 452 4542 exclusion phecode
389.2 Conductive hearing loss Sense Organs 0.851 0.773 – 0.936 0.00091 445 4480 exclusion phecode
389.4 Tinnitus Sense Organs 1.02 0.927 – 1.11 0.743 505 5126 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1 0.975 – 1.03 0.782 4879 48836 exclusion phecode
394.2 Mitral valve disease Circulatory System 0.986 0.95 – 1.02 0.467 2980 29842 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.04 0.977 – 1.1 0.238 1279 12774 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.01 0.949 – 1.08 0.74 1053 10537 exclusion phecode
395 Heart valve disorders Circulatory System 0.993 0.962 – 1.03 0.678 4206 42105 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.983 0.946 – 1.02 0.38 2878 28826 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.955 0.847 – 1.08 0.45 276 2757 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.19 0.969 – 1.45 0.0972 105 1036 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.878 0.711 – 1.08 0.224 96 967 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.01 0.953 – 1.06 0.85 1491 14912 exclusion phecode
396 Abnormal heart sounds Circulatory System 0.966 0.906 – 1.03 0.294 1038 10412 exclusion phecode
401 Hypertension Circulatory System 1.01 1 – 1.02 0.0373 73571 266162 exclusion phecode
401.1 Essential hypertension Circulatory System 1.01 1 – 1.02 0.0323 73348 265945 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.02 0.969 – 1.06 0.513 1882 18975 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 0.958 0.862 – 1.06 0.427 370 3690 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.03 0.98 – 1.09 0.225 1527 15432 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.07 0.897 – 1.27 0.463 142 1434 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 0.992 0.94 – 1.05 0.772 1472 14747 exclusion phecode
411 Ischemic Heart Disease Circulatory System 0.991 0.979 – 1 0.135 31158 210040 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.983 0.955 – 1.01 0.235 5139 51385 exclusion phecode
411.2 Myocardial infarction Circulatory System 0.975 0.957 – 0.993 0.00746 11921 112495 exclusion phecode
411.3 Angina pectoris Circulatory System 0.992 0.976 – 1.01 0.349 15835 143328 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 0.98 0.965 – 0.994 0.00594 20134 154273 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.01 0.94 – 1.1 0.706 697 6981 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.99 0.973 – 1.01 0.224 15236 131466 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.973 0.918 – 1.03 0.358 1213 12149 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 0.969 0.924 – 1.02 0.193 1815 18184 exclusion phecode
414.2 ASCVD Circulatory System 1.12 0.884 – 1.41 0.35 72 718 exclusion phecode
415 Pulmonary heart disease Circulatory System 0.995 0.964 – 1.03 0.729 4390 44676 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.1 0.866 – 1.39 0.44 75 747 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.996 0.915 – 1.08 0.916 598 5984 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.02 0.925 – 1.12 0.698 445 4458 exclusion phecode
416 Cardiomegaly Circulatory System 0.99 0.952 – 1.03 0.617 2675 26745 exclusion phecode
418 Nonspecific chest pain Circulatory System 0.99 0.978 – 1 0.0952 28480 269211 exclusion phecode
418.1 Precordial pain Circulatory System 0.976 0.943 – 1.01 0.159 3535 35427 exclusion phecode
420 Carditis Circulatory System 1.01 0.962 – 1.05 0.775 2092 21003 exclusion phecode
420.1 Myocarditis Circulatory System 1.05 0.88 – 1.26 0.574 127 1265 exclusion phecode
420.2 Pericarditis Circulatory System 1 0.95 – 1.06 0.877 1330 13338 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.06 0.926 – 1.21 0.396 222 2220 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.08 0.895 – 1.31 0.41 113 1126 exclusion phecode
420.3 Endocarditis Circulatory System 0.983 0.911 – 1.06 0.664 711 7181 exclusion phecode
425 Cardiomyopathy Circulatory System 1 0.947 – 1.06 0.939 1265 12677 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.995 0.939 – 1.05 0.855 1231 12329 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.947 0.797 – 1.13 0.535 132 1328 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.964 0.823 – 1.13 0.645 163 1626 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 0.988 0.765 – 1.28 0.928 60 600 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.01 0.987 – 1.04 0.344 6886 68994 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.02 0.977 – 1.07 0.359 2108 21123 exclusion phecode
426.21 First degree AV block Circulatory System 1.02 0.959 – 1.09 0.476 986 9850 exclusion phecode
426.23 Second degree AV block Circulatory System 0.972 0.882 – 1.07 0.564 449 4502 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1.05 0.968 – 1.15 0.226 585 5855 exclusion phecode
426.25 Other heart block Circulatory System 1 0.84 – 1.2 0.976 131 1314 exclusion phecode
426.3 Bundle branch block Circulatory System 0.996 0.961 – 1.03 0.83 3322 33278 exclusion phecode
426.31 Right bundle branch block Circulatory System 1 0.948 – 1.05 0.986 1489 14898 exclusion phecode
426.32 Left bundle branch block Circulatory System 0.988 0.94 – 1.04 0.618 1741 17458 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.916 0.802 – 1.05 0.197 233 2322 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 0.994 0.769 – 1.28 0.963 60 599 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.04 0.994 – 1.08 0.0912 2469 24725 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.02 0.981 – 1.07 0.268 2268 22720 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.01 0.999 – 1.03 0.0652 24095 205351 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.02 0.983 – 1.06 0.288 3186 31933 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.02 0.977 – 1.06 0.363 2333 23407 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.01 0.946 – 1.08 0.735 933 9351 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.01 0.994 – 1.03 0.22 14575 133147 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.974 0.94 – 1.01 0.149 3217 32208 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.976 0.921 – 1.04 0.425 1189 11897 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.979 0.878 – 1.09 0.708 344 3433 exclusion phecode
427.42 Cardiac arrest Circulatory System 0.974 0.914 – 1.04 0.431 986 9870 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.01 0.943 – 1.08 0.807 949 9514 exclusion phecode
427.6 Premature beats Circulatory System 1.02 0.93 – 1.11 0.724 533 5347 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 0.946 0.791 – 1.13 0.539 116 1164 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.06 1.01 – 1.11 0.014 2161 21793 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.971 0.877 – 1.08 0.575 399 4011 exclusion phecode
427.9 Palpitations Circulatory System 1.02 0.986 – 1.05 0.252 3793 37951 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.986 0.96 – 1.01 0.314 5590 55917 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 0.981 0.939 – 1.03 0.398 2108 21071 exclusion phecode
428.2 Heart failure NOS Circulatory System 0.999 0.969 – 1.03 0.937 4441 44442 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.08 1 – 1.17 0.0485 715 7151 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.07 0.827 – 1.38 0.606 64 639 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.07 0.98 – 1.18 0.127 521 5199 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.08 0.937 – 1.25 0.279 196 1973 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.06 1.01 – 1.11 0.0278 1876 18773 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.1 1.02 – 1.18 0.00968 831 8322 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.06 0.985 – 1.15 0.117 764 7635 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1 0.886 – 1.14 0.944 266 2662 exclusion phecode
433 Cerebrovascular disease Circulatory System 0.998 0.977 – 1.02 0.882 8702 87207 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.975 0.918 – 1.03 0.405 1184 11807 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 0.993 0.866 – 1.14 0.919 226 2263 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.991 0.96 – 1.02 0.555 4209 42212 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.998 0.949 – 1.05 0.937 1670 16747 exclusion phecode
433.3 Cerebral ischemia Circulatory System 0.979 0.942 – 1.02 0.273 2882 28903 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 0.979 0.937 – 1.02 0.346 2128 21325 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.14 1.03 – 1.27 0.0131 390 3922 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.02 0.964 – 1.08 0.475 1272 12747 exclusion phecode
440 Atherosclerosis Circulatory System 1.02 0.966 – 1.08 0.461 1373 13797 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.1 0.91 – 1.33 0.321 112 1126 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.05 0.977 – 1.13 0.188 802 8055 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 0.866 0.769 – 0.975 0.0172 285 2863 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.06 0.97 – 1.15 0.202 604 6134 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.08 0.95 – 1.22 0.247 277 2815 exclusion phecode
442 Other aneurysm Circulatory System 1.06 1.01 – 1.11 0.0226 1887 18922 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.04 0.986 – 1.1 0.15 1457 14603 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.01 0.948 – 1.08 0.704 930 9330 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 0.971 0.796 – 1.18 0.771 102 1018 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.11 0.947 – 1.3 0.198 168 1693 exclusion phecode
442.4 Arterial dissection Circulatory System 1.27 0.968 – 1.67 0.0845 54 549 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.13 0.975 – 1.3 0.105 200 2018 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.01 0.982 – 1.05 0.386 3898 39169 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.05 0.989 – 1.12 0.112 1136 11392 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.06 0.955 – 1.18 0.269 382 3874 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.01 0.978 – 1.05 0.493 3665 36803 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.99 0.951 – 1.03 0.631 2567 25792 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 0.98 0.917 – 1.05 0.565 914 9231 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.985 0.903 – 1.07 0.727 551 5546 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.989 0.921 – 1.06 0.75 814 8192 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.923 0.796 – 1.07 0.289 188 1871 exclusion phecode
446.5 Giant cell arteritis Circulatory System 0.996 0.898 – 1.1 0.932 384 3862 exclusion phecode
446.9 Arteritis NOS Circulatory System 0.911 0.8 – 1.04 0.16 235 2391 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1 0.946 – 1.06 0.98 1321 13279 exclusion phecode
447.1 Stricture of artery Circulatory System 1.02 0.948 – 1.09 0.638 865 8691 exclusion phecode
448 Disease of capillaries Circulatory System 0.898 0.757 – 1.06 0.215 140 1412 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.05 0.968 – 1.13 0.247 674 7014 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.98 0.949 – 1.01 0.23 3890 39578 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.981 0.948 – 1.01 0.26 3621 36881 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1.01 0.922 – 1.1 0.891 548 5630 exclusion phecode
454 Varicose veins Circulatory System 1.01 0.986 – 1.03 0.57 11135 111604 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1.01 0.986 – 1.02 0.597 11450 114798 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.04 0.959 – 1.13 0.342 621 6307 exclusion phecode
455 Hemorrhoids Circulatory System 1 0.988 – 1.02 0.804 23360 233857 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.946 0.819 – 1.09 0.455 184 1865 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.861 0.698 – 1.06 0.162 96 964 exclusion phecode
458 Hypotension Circulatory System 0.997 0.97 – 1.02 0.805 5701 57600 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.04 0.979 – 1.1 0.216 1323 13333 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.12 0.976 – 1.28 0.107 229 2342 exclusion phecode
458.9 Hypotension NOS Circulatory System 0.977 0.943 – 1.01 0.184 3453 34907 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.01 0.993 – 1.03 0.293 16126 160302 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 0.829 0.698 – 0.984 0.0323 141 1414 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.01 0.995 – 1.03 0.191 15962 158936 exclusion phecode
464 Acute sinusitis Respiratory 0.911 0.789 – 1.05 0.2 196 1950 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.03 0.986 – 1.08 0.189 2246 22729 exclusion phecode
465.2 Acute pharyngitis Respiratory 1.06 0.984 – 1.14 0.126 821 8308 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.07 0.91 – 1.25 0.422 165 1643 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.99 0.961 – 1.02 0.533 4642 46435 exclusion phecode
471 Nasal polyps Respiratory 0.987 0.953 – 1.02 0.474 3292 32919 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.05 0.979 – 1.12 0.187 955 9565 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1 0.96 – 1.04 0.992 2548 25462 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.08 0.886 – 1.32 0.435 104 1037 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.933 0.826 – 1.05 0.27 263 2641 exclusion phecode
473.4 Voice disturbance Respiratory 0.998 0.938 – 1.06 0.95 1076 10760 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1 0.953 – 1.05 0.966 1761 17677 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.03 0.947 – 1.13 0.468 547 5471 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.971 0.913 – 1.03 0.347 1113 11173 exclusion phecode
475 Chronic sinusitis Respiratory 0.989 0.95 – 1.03 0.594 2576 25800 exclusion phecode
476 Allergic rhinitis Respiratory 0.975 0.914 – 1.04 0.427 1044 10542 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 0.99 0.95 – 1.03 0.637 2432 24383 exclusion phecode
478 Throat pain Respiratory 0.986 0.888 – 1.1 0.798 375 3774 exclusion phecode
479 Other upper respiratory disease Respiratory 0.995 0.963 – 1.03 0.741 4058 40631 exclusion phecode
480 Pneumonia Respiratory 1.01 0.989 – 1.03 0.357 10236 103097 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.01 0.99 – 1.04 0.248 6578 66219 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.02 0.989 – 1.04 0.255 5828 58694 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 0.882 0.717 – 1.09 0.238 92 927 exclusion phecode
480.2 Viral pneumonia Respiratory 1.1 0.861 – 1.42 0.433 72 718 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.87 0.711 – 1.07 0.179 98 987 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.03 0.957 – 1.11 0.436 787 7935 exclusion phecode
481 Influenza Respiratory 0.957 0.854 – 1.07 0.459 324 3272 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.06 0.921 – 1.23 0.397 191 1928 exclusion phecode
495 Asthma Respiratory 0.998 0.986 – 1.01 0.797 25543 249522 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.14 0.996 – 1.29 0.0574 248 2504 exclusion phecode
496 Chronic airway obstruction Respiratory 0.993 0.973 – 1.01 0.505 10360 101231 exclusion phecode
496.1 Emphysema Respiratory 0.952 0.907 – 1 0.0512 1729 17404 exclusion phecode
496.2 Chronic bronchitis Respiratory 0.998 0.961 – 1.04 0.907 2930 29408 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.01 0.969 – 1.05 0.708 2691 27005 exclusion phecode
496.3 Bronchiectasis Respiratory 0.95 0.905 – 0.996 0.0331 1874 18784 exclusion phecode
497 Bronchitis Respiratory 1.03 0.95 – 1.12 0.463 622 6246 exclusion phecode
500 Lung disease due to external agents Respiratory 0.964 0.873 – 1.06 0.469 411 4093 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.985 0.791 – 1.23 0.892 79 784 exclusion phecode
500.2 Pneumoconiosis Respiratory 0.991 0.869 – 1.13 0.899 243 2407 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.02 0.945 – 1.11 0.554 650 6540 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.893 0.834 – 0.956 0.00107 911 9177 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.06 0.963 – 1.16 0.246 502 5065 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.918 0.822 – 1.03 0.135 326 3270 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.04 0.796 – 1.37 0.762 61 610 exclusion phecode
506 Empyema and pneumothorax Respiratory 1 0.942 – 1.06 0.957 1119 11331 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 0.992 0.967 – 1.02 0.547 6253 64082 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.974 0.929 – 1.02 0.258 1970 19893 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.01 0.97 – 1.05 0.638 2581 25981 exclusion phecode
509.1 Respiratory failure Respiratory 1.03 0.981 – 1.07 0.251 2051 20670 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.02 0.974 – 1.07 0.379 1792 18071 exclusion phecode
509.5 Respiratory arrest Respiratory 0.927 0.784 – 1.1 0.371 142 1427 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.937 0.844 – 1.04 0.222 385 3854 exclusion phecode
510 Other diseases of lung Respiratory 0.994 0.923 – 1.07 0.872 752 7528 exclusion phecode
512 Other symptoms of respiratory system Respiratory 0.977 0.956 – 0.998 0.036 8940 90064 exclusion phecode
512.1 Wheezing Respiratory 0.89 0.78 – 1.02 0.0842 219 2188 exclusion phecode
512.2 Painful respiration Respiratory 0.963 0.834 – 1.11 0.606 203 2071 exclusion phecode
512.7 Shortness of breath Respiratory 0.989 0.962 – 1.02 0.403 5783 58304 exclusion phecode
512.8 Cough Respiratory 0.97 0.933 – 1.01 0.117 2844 28554 exclusion phecode
512.9 Other dyspnea Respiratory 0.964 0.901 – 1.03 0.285 903 9099 exclusion phecode
513 Respiratory abnormalities Respiratory 1.02 0.938 – 1.11 0.654 610 6099 exclusion phecode
513.3 Hypoventilation Respiratory 0.987 0.787 – 1.24 0.91 83 829 exclusion phecode
513.4 Hyperventilation Respiratory 1.09 0.963 – 1.24 0.17 277 2772 exclusion phecode
513.8 Disorders of diaphragm Respiratory 0.854 0.725 – 1.01 0.0578 153 1537 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.01 0.967 – 1.05 0.708 2443 24591 exclusion phecode
516 Abnormal sputum Respiratory 1.02 0.975 – 1.07 0.4 2125 21283 exclusion phecode
516.1 Hemoptysis Respiratory 1.02 0.974 – 1.07 0.418 2066 20693 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.992 0.971 – 1.01 0.432 9276 93373 exclusion phecode
519.2 Respiratory complications Respiratory 0.992 0.884 – 1.11 0.885 322 3267 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.991 0.97 – 1.01 0.442 8770 88230 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.04 0.919 – 1.17 0.557 300 3035 exclusion phecode
520 Disorders of tooth development Digestive 0.984 0.94 – 1.03 0.501 2036 20297 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.06 0.79 – 1.42 0.701 53 528 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.988 0.947 – 1.03 0.579 2354 23469 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 0.98 0.944 – 1.02 0.277 3007 30124 exclusion phecode
521.1 Dental caries Digestive 0.981 0.945 – 1.02 0.316 3017 30233 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.03 0.98 – 1.08 0.247 1764 17690 exclusion phecode
522.5 Periapical abscess Digestive 1 0.942 – 1.06 0.996 1166 11698 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.01 0.963 – 1.07 0.614 1672 16753 exclusion phecode
523.1 Gingivitis Digestive 1.02 0.84 – 1.24 0.843 113 1125 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.01 0.949 – 1.07 0.802 1160 11611 exclusion phecode
523.31 Acute periodontitis Digestive 0.977 0.903 – 1.06 0.573 663 6653 exclusion phecode
523.32 Chronic periodontitis Digestive 1 0.918 – 1.09 0.958 557 5564 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.02 0.913 – 1.14 0.709 330 3303 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.956 0.852 – 1.07 0.439 304 3044 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.969 0.931 – 1.01 0.12 2659 26640 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.02 0.789 – 1.32 0.87 71 718 exclusion phecode
526 Diseases of the jaws Digestive 1 0.938 – 1.07 0.928 924 9246 exclusion phecode
526.1 Cysts of the jaws Digestive 0.941 0.842 – 1.05 0.285 328 3284 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.08 0.829 – 1.41 0.567 60 608 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.14 0.994 – 1.3 0.0614 240 2390 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.12 0.978 – 1.29 0.0999 233 2322 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 1.01 0.824 – 1.23 0.959 109 1095 exclusion phecode
526.9 Jaw disease NOS Digestive 0.995 0.87 – 1.14 0.944 232 2317 exclusion phecode
527 Diseases of the salivary glands Digestive 1.01 0.935 – 1.09 0.779 688 6917 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.13 0.902 – 1.43 0.281 84 835 exclusion phecode
527.2 Sialoadenitis Digestive 1 0.901 – 1.12 0.937 362 3637 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1 0.784 – 1.28 0.987 62 616 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.01 0.842 – 1.22 0.904 119 1197 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.03 0.995 – 1.06 0.0966 3852 38596 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.08 0.984 – 1.19 0.106 463 4657 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.09 0.986 – 1.21 0.0905 385 3862 exclusion phecode
528.12 Oral aphthae Digestive 1.03 0.825 – 1.28 0.806 83 839 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.992 0.854 – 1.15 0.919 179 1782 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.917 0.764 – 1.1 0.35 122 1212 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.863 0.701 – 1.06 0.165 94 936 exclusion phecode
528.5 Diseases of lips Digestive 1.06 0.977 – 1.15 0.165 678 6789 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.11 0.982 – 1.25 0.0961 306 3067 exclusion phecode
528.7 Sialolithiasis Digestive 1.03 0.92 – 1.16 0.583 313 3124 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 0.987 0.931 – 1.05 0.659 1228 12272 exclusion phecode
529.1 Glossitis Digestive 0.993 0.882 – 1.12 0.91 298 2979 exclusion phecode
530 Diseases of esophagus Digestive 1 0.991 – 1.01 0.625 33281 278233 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1 0.99 – 1.01 0.757 31093 271511 exclusion phecode
530.11 GERD Digestive 1.01 0.996 – 1.02 0.16 22510 225056 exclusion phecode
530.12 Ulcer of esophagus Digestive 0.99 0.962 – 1.02 0.503 5174 51943 exclusion phecode
530.14 Reflux esophagitis Digestive 1 0.981 – 1.02 0.938 10402 104181 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.969 0.922 – 1.02 0.227 1671 16761 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1.04 0.99 – 1.09 0.126 1859 18644 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.1 1.01 – 1.19 0.0282 632 6341 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.1 0.937 – 1.3 0.24 151 1525 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.03 0.923 – 1.15 0.59 340 3413 exclusion phecode
530.9 Heartburn Digestive 0.991 0.947 – 1.04 0.683 2079 20790 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.993 0.969 – 1.02 0.592 7070 70855 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1 0.924 – 1.09 0.958 633 6364 exclusion phecode
531.2 Gastric ulcer Digestive 1 0.971 – 1.03 0.892 4072 40805 exclusion phecode
531.3 Duodenal ulcer Digestive 0.972 0.936 – 1.01 0.134 2986 29933 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.04 0.946 – 1.15 0.395 426 4258 exclusion phecode
532 Dysphagia Digestive 1.02 0.992 – 1.04 0.176 6396 64115 exclusion phecode
535 Gastritis and duodenitis Digestive 0.996 0.984 – 1.01 0.569 27951 260620 exclusion phecode
535.1 Acute gastritis Digestive 1.02 0.961 – 1.08 0.526 1178 11797 exclusion phecode
535.2 Atrophic gastritis Digestive 0.935 0.841 – 1.04 0.219 370 3678 exclusion phecode
535.6 Duodenitis Digestive 0.993 0.969 – 1.02 0.537 7561 75720 exclusion phecode
535.8 Other specified gastritis Digestive 1.01 0.985 – 1.03 0.506 8024 80467 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.06 0.873 – 1.28 0.578 120 1189 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.06 0.933 – 1.2 0.378 258 2565 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 0.993 0.958 – 1.03 0.701 3360 33790 exclusion phecode
540 Appendiceal conditions Digestive 0.999 0.963 – 1.04 0.958 3078 30782 exclusion phecode
540.1 Appendicitis Digestive 0.999 0.962 – 1.04 0.974 2885 28863 exclusion phecode
540.11 Acute appendicitis Digestive 0.996 0.957 – 1.04 0.86 2592 25928 exclusion phecode
550 Abdominal hernia Digestive 0.996 0.986 – 1.01 0.441 45208 281733 exclusion phecode
550.1 Inguinal hernia Digestive 1.01 0.997 – 1.03 0.114 15787 123174 exclusion phecode
550.2 Diaphragmatic hernia Digestive 0.986 0.974 – 0.999 0.0306 26342 238098 exclusion phecode
550.3 Femoral hernia Digestive 0.993 0.916 – 1.08 0.867 645 6476 exclusion phecode
550.4 Umbilical hernia Digestive 0.979 0.947 – 1.01 0.219 3695 37019 exclusion phecode
550.5 Ventral hernia Digestive 1.02 0.984 – 1.06 0.281 3375 34240 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.01 0.975 – 1.04 0.726 4428 44338 exclusion phecode
555.1 Regional enteritis Digestive 1.03 0.98 – 1.08 0.239 1730 17293 exclusion phecode
555.2 Ulcerative colitis Digestive 0.996 0.96 – 1.03 0.842 3163 31723 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 0.987 0.904 – 1.08 0.779 535 5370 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.01 0.945 – 1.07 0.834 1053 10561 exclusion phecode
556.1 Ulceration of intestine Digestive 1.01 0.936 – 1.1 0.727 668 6693 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.871 0.775 – 0.979 0.0208 298 2976 exclusion phecode
557.1 Celiac disease Digestive 0.972 0.926 – 1.02 0.243 1820 18332 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.01 0.998 – 1.03 0.0914 15368 154673 exclusion phecode
559 Ileostomy status Digestive 0.97 0.922 – 1.02 0.242 1611 16498 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.02 0.982 – 1.05 0.381 3778 39227 exclusion phecode
560.1 Paralytic ileus Digestive 1.02 0.935 – 1.12 0.603 508 5217 exclusion phecode
560.2 Impaction of intestine Digestive 1.05 0.925 – 1.19 0.457 266 2661 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.997 0.927 – 1.07 0.945 810 8295 exclusion phecode
560.4 Other intestinal obstruction Digestive 1.01 0.97 – 1.04 0.743 3211 33451 exclusion phecode
561 Symptoms involving digestive system Digestive 0.99 0.974 – 1.01 0.224 15635 157203 exclusion phecode
561.1 Diarrhea Digestive 0.992 0.901 – 1.09 0.864 463 4640 exclusion phecode
561.2 Flatulence Digestive 0.998 0.948 – 1.05 0.926 1653 16819 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1 0.988 – 1.01 0.941 26561 211145 exclusion phecode
562.1 Diverticulosis Digestive 1 0.987 – 1.01 0.984 26519 211095 exclusion phecode
563 Constipation Digestive 0.987 0.967 – 1.01 0.207 10155 102836 exclusion phecode
564 Functional digestive disorders Digestive 0.997 0.983 – 1.01 0.646 21490 209405 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 0.993 0.965 – 1.02 0.622 5458 54939 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 0.998 0.949 – 1.05 0.938 1621 16416 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 0.998 0.981 – 1.01 0.799 15109 151297 exclusion phecode
565 Anal and rectal conditions Digestive 0.996 0.979 – 1.01 0.641 14659 147136 exclusion phecode
565.1 Anal and rectal polyp Digestive 0.997 0.973 – 1.02 0.804 7318 73350 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.01 0.943 – 1.08 0.788 911 9273 exclusion phecode
568 Other disorders of peritoneum Digestive 1.02 0.983 – 1.06 0.299 3186 32467 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.02 0.98 – 1.06 0.353 3031 30860 exclusion phecode
569 Other disorders of intestine Digestive 1.01 0.977 – 1.04 0.583 4126 41782 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.953 0.803 – 1.13 0.586 143 1474 exclusion phecode
569.2 Gastrointestinal complications Digestive 0.971 0.884 – 1.07 0.539 470 4852 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1 0.964 – 1.04 0.951 2935 29556 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.01 0.965 – 1.07 0.561 1674 16871 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.02 0.837 – 1.24 0.858 113 1137 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 0.973 0.854 – 1.11 0.68 255 2558 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.967 0.905 – 1.03 0.31 969 9782 exclusion phecode
571.81 Portal hypertension Digestive 0.966 0.884 – 1.06 0.44 527 5273 exclusion phecode
572 Ascites (non malignant) Digestive 1.03 0.97 – 1.08 0.381 1330 15409 exclusion phecode
573 Other disorders of liver Digestive 1.02 0.97 – 1.08 0.399 1472 14942 exclusion phecode
573.2 Liver replaced by transplant Digestive 0.996 0.803 – 1.23 0.967 96 957 exclusion phecode
573.3 Hepatomegaly Digestive 0.969 0.863 – 1.09 0.598 296 2961 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.01 0.944 – 1.08 0.743 891 8935 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1 0.967 – 1.04 0.934 3429 34483 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 0.867 0.754 – 0.996 0.0444 206 2085 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1 0.985 – 1.02 0.898 15507 155400 exclusion phecode
574.1 Cholelithiasis Digestive 0.998 0.981 – 1.02 0.85 13461 134909 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.982 0.931 – 1.04 0.496 1497 14989 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.01 0.983 – 1.04 0.433 5403 54042 exclusion phecode
574.2 Calculus of bile duct Digestive 1.02 0.976 – 1.06 0.443 2597 26072 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.995 0.957 – 1.04 0.818 2734 27416 exclusion phecode
575 Other biliary tract disease Digestive 1.01 0.973 – 1.04 0.733 3836 38582 exclusion phecode
575.1 Cholangitis Digestive 1.02 0.925 – 1.11 0.747 489 4930 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.05 0.974 – 1.13 0.209 767 7737 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 1.02 0.927 – 1.13 0.669 457 4552 exclusion phecode
575.7 Other disorders of gallbladder Digestive 0.998 0.945 – 1.05 0.937 1402 14046 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.01 0.95 – 1.08 0.686 1027 10320 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.903 0.809 – 1.01 0.0648 342 3480 exclusion phecode
577 Diseases of pancreas Digestive 0.99 0.952 – 1.03 0.632 2657 26575 exclusion phecode
577.1 Acute pancreatitis Digestive 0.994 0.949 – 1.04 0.786 1993 19876 exclusion phecode
577.2 Chronic pancreatitis Digestive 0.958 0.878 – 1.05 0.336 514 5138 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.06 0.949 – 1.17 0.315 361 3635 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1 0.988 – 1.02 0.793 20505 205637 exclusion phecode
578.1 Hematemesis Digestive 0.995 0.95 – 1.04 0.843 1933 19515 exclusion phecode
578.2 Blood in stool Digestive 1 0.964 – 1.05 0.848 2613 26214 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1 0.985 – 1.02 0.769 13004 130330 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.995 0.968 – 1.02 0.739 5250 52643 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.01 0.959 – 1.07 0.658 1439 15426 exclusion phecode
579.2 Splenomegaly Digestive 1.06 0.96 – 1.17 0.247 420 4237 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.976 0.928 – 1.03 0.352 1646 16484 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.01 0.955 – 1.06 0.805 1517 15303 exclusion phecode
580.1 Glomerulonephritis Genitourinary 0.995 0.933 – 1.06 0.876 1039 10505 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.767 0.606 – 0.969 0.0265 73 737 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.986 0.828 – 1.18 0.878 135 1352 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.01 0.945 – 1.09 0.707 864 8738 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.01 0.921 – 1.11 0.805 468 4685 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.915 0.803 – 1.04 0.183 245 2453 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.925 0.813 – 1.05 0.233 252 2523 exclusion phecode
585 Renal failure Genitourinary 1.01 0.981 – 1.03 0.641 6878 69589 exclusion phecode
585.1 Acute renal failure Genitourinary 1.02 0.987 – 1.05 0.27 4459 45202 exclusion phecode
585.2 Renal failure NOS Genitourinary 0.984 0.933 – 1.04 0.554 1433 14600 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1 0.962 – 1.04 0.96 2617 26413 exclusion phecode
585.31 Renal dialysis Genitourinary 0.987 0.9 – 1.08 0.781 494 4942 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.02 0.982 – 1.05 0.341 3306 33506 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.955 0.828 – 1.1 0.525 204 2083 exclusion phecode
586.11 Small kidney Genitourinary 0.985 0.844 – 1.15 0.843 177 1795 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 0.995 0.939 – 1.05 0.863 1247 12559 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.1 0.871 – 1.38 0.435 80 798 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.01 0.947 – 1.09 0.7 879 9099 exclusion phecode
587 Kidney replaced by transpant Genitourinary 0.975 0.878 – 1.08 0.643 366 3678 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 0.957 0.774 – 1.18 0.68 97 984 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 0.983 0.814 – 1.19 0.86 113 1154 exclusion phecode
590 Pyelonephritis Genitourinary 1.05 0.988 – 1.11 0.126 1317 13227 exclusion phecode
591 Urinary tract infection Genitourinary 0.998 0.979 – 1.02 0.803 12236 123500 exclusion phecode
592 Cystitis and urethritis Genitourinary 0.993 0.956 – 1.03 0.719 2941 29569 exclusion phecode
592.1 Cystitis Genitourinary 0.996 0.958 – 1.03 0.82 2879 28948 exclusion phecode
592.11 Acute cystitis Genitourinary 0.957 0.805 – 1.14 0.615 138 1369 exclusion phecode
592.12 Chronic cystitis Genitourinary 0.918 0.857 – 0.983 0.0144 882 8867 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 0.949 0.831 – 1.08 0.436 247 2474 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.98 0.839 – 1.14 0.796 165 1655 exclusion phecode
593 Hematuria Genitourinary 0.996 0.98 – 1.01 0.666 15988 159776 exclusion phecode
594 Urinary calculus Genitourinary 0.991 0.966 – 1.02 0.498 6362 63655 exclusion phecode
594.1 Calculus of kidney Genitourinary 0.987 0.952 – 1.02 0.482 3169 31706 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.04 0.966 – 1.12 0.305 776 7750 exclusion phecode
594.3 Calculus of ureter Genitourinary 0.975 0.935 – 1.02 0.224 2396 23987 exclusion phecode
594.8 Renal colic Genitourinary 0.955 0.913 – 0.999 0.044 2046 20463 exclusion phecode
595 Hydronephrosis Genitourinary 1.02 0.973 – 1.07 0.412 1847 19346 exclusion phecode
596 Other disorders of bladder Genitourinary 1 0.983 – 1.02 0.714 9724 97567 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.02 0.97 – 1.06 0.516 1969 19685 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 0.987 0.939 – 1.04 0.626 1644 16517 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.02 0.984 – 1.05 0.32 3889 39016 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.01 0.973 – 1.04 0.655 3303 33043 exclusion phecode
597.2 Urinary complications NEC Genitourinary 0.91 0.721 – 1.15 0.431 76 774 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.01 0.975 – 1.04 0.622 3514 35226 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.974 0.866 – 1.09 0.653 299 3028 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.996 0.981 – 1.01 0.62 18277 183650 exclusion phecode
599.1 Urinary obstruction Genitourinary 1.21 1.03 – 1.42 0.0213 162 1667 exclusion phecode
599.2 Retention of urine Genitourinary 1 0.975 – 1.03 0.989 6676 67074 exclusion phecode
599.3 Dysuria Genitourinary 1.02 0.964 – 1.09 0.45 1189 11932 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.981 0.96 – 1 0.0987 8663 87023 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.03 0.994 – 1.06 0.117 3999 40045 exclusion phecode
599.6 Oliguria and anuria Genitourinary 0.981 0.807 – 1.19 0.846 104 1058 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.02 0.788 – 1.31 0.895 62 619 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1.02 0.975 – 1.07 0.359 1907 19117 exclusion phecode
600 Hyperplasia of prostate Genitourinary 1.01 0.991 – 1.03 0.305 11093 87892 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 1.01 0.963 – 1.05 0.771 2081 20818 exclusion phecode
601.1 Prostatitis Genitourinary 1.01 0.96 – 1.06 0.698 1563 15644 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.942 0.828 – 1.07 0.369 234 2358 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1.02 0.955 – 1.09 0.542 910 9089 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.95 0.731 – 1.23 0.7 59 588 exclusion phecode
601.4 Balanoposthitis Genitourinary 0.965 0.856 – 1.09 0.554 287 2864 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.06 0.942 – 1.19 0.338 303 3019 exclusion phecode
602 Other disorders of prostate Genitourinary 1.01 0.957 – 1.07 0.687 1341 13408 exclusion phecode
603 Other disorders of testis Genitourinary 1.01 0.963 – 1.05 0.772 2150 21512 exclusion phecode
603.1 Hydrocele Genitourinary 0.972 0.92 – 1.03 0.307 1339 13402 exclusion phecode
604 Disorders of penis Genitourinary 0.992 0.958 – 1.03 0.656 3280 32779 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.985 0.948 – 1.02 0.445 2719 27172 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.986 0.875 – 1.11 0.815 278 2800 exclusion phecode
608 Other disorders of male genital organs Genitourinary 1.01 0.968 – 1.05 0.772 2822 28236 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.926 0.806 – 1.06 0.277 214 2138 exclusion phecode
609.1 Infertility, male Genitourinary 0.987 0.776 – 1.26 0.919 63 638 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.839 0.717 – 0.982 0.0287 169 1698 exclusion phecode
610 Benign mammary dysplasias Genitourinary 1.02 0.975 – 1.06 0.439 2464 24658 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.988 0.922 – 1.06 0.718 918 9194 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1.03 0.918 – 1.16 0.586 302 3046 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 1.04 0.922 – 1.17 0.519 299 3007 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 1.02 0.969 – 1.08 0.398 1381 13778 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.96 0.888 – 1.04 0.316 690 6918 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.08 1.03 – 1.14 0.0034 1566 15625 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.933 0.703 – 1.24 0.632 56 569 exclusion phecode
611.3 Lump or mass in breast Genitourinary 1.09 1.04 – 1.15 0.00101 1515 15108 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.01 0.943 – 1.08 0.753 881 8847 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.01 0.943 – 1.09 0.735 845 8464 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 1.08 0.856 – 1.37 0.507 70 717 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 1.02 0.972 – 1.08 0.376 1640 16430 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.08 0.994 – 1.16 0.0704 715 7165 exclusion phecode
613.5 Mastodynia Genitourinary 0.897 0.707 – 1.14 0.369 76 766 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 1.01 0.937 – 1.1 0.721 695 6972 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 0.991 0.883 – 1.11 0.88 324 3264 exclusion phecode
613.9 Breast disorder NOS Genitourinary 0.978 0.847 – 1.13 0.756 207 2057 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.04 1.01 – 1.07 0.00413 5533 56832 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.02 0.981 – 1.07 0.289 2436 25241 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.02 0.951 – 1.1 0.53 797 8268 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.907 0.693 – 1.19 0.477 60 605 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.07 0.966 – 1.18 0.197 405 4201 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.993 0.886 – 1.11 0.908 336 3491 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.05 0.926 – 1.19 0.447 273 2760 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.05 1.01 – 1.1 0.0125 2544 25889 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.09 1.03 – 1.16 0.00298 1294 13111 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.01 0.906 – 1.12 0.91 410 4250 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.05 0.97 – 1.13 0.242 752 7539 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.03 0.911 – 1.17 0.627 267 2723 exclusion phecode
615 Endometriosis Genitourinary 1.03 0.996 – 1.06 0.0877 3923 40099 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.15 1.02 – 1.31 0.0245 283 3014 exclusion phecode
618 Genital prolapse Genitourinary 0.999 0.98 – 1.02 0.936 11598 116086 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 1.01 0.986 – 1.04 0.417 7333 73454 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.983 0.956 – 1.01 0.241 5360 53575 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.958 0.875 – 1.05 0.356 505 5090 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1 0.924 – 1.08 0.975 669 6748 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 0.992 0.97 – 1.02 0.51 8535 86824 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.01 0.935 – 1.1 0.759 686 7246 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 1.01 0.973 – 1.05 0.619 3277 33083 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.98 0.942 – 1.02 0.309 2824 28467 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.01 0.958 – 1.06 0.767 1734 17575 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.948 0.895 – 1 0.0715 1290 13401 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.999 0.939 – 1.06 0.98 1116 11228 exclusion phecode
622 Polyp of female genital organs Genitourinary 1.04 1.02 – 1.06 0.000398 10357 104174 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 1.04 1.01 – 1.06 0.00411 7755 78151 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 1.06 1.03 – 1.1 0.000808 3415 34175 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.01 0.951 – 1.07 0.78 1251 12612 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.989 0.918 – 1.07 0.772 768 7913 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.952 0.827 – 1.09 0.489 217 2355 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 0.998 0.902 – 1.1 0.97 427 4367 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.978 0.952 – 1.01 0.113 5806 58283 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.05 1.01 – 1.09 0.0258 2840 28601 exclusion phecode
625.1 Dyspareunia Genitourinary 1.06 0.999 – 1.13 0.0534 1173 11840 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.03 1.02 – 1.05 0.000194 16040 114478 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.04 1.02 – 1.06 7.52e-05 14009 109411 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.881 0.723 – 1.07 0.208 108 1093 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1.05 1.03 – 1.07 1.29e-05 9656 91339 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 1.01 0.967 – 1.06 0.584 1972 19737 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 1.06 1.02 – 1.1 0.001 3778 37843 exclusion phecode
626.2 Dysmenorrhea Genitourinary 1.06 1.01 – 1.11 0.0253 1769 17689 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.97 0.824 – 1.14 0.718 159 1579 exclusion phecode
626.8 Infertility, female Genitourinary 1.03 0.972 – 1.09 0.331 1354 13563 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 1 0.984 – 1.03 0.681 10268 103317 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 1 0.982 – 1.03 0.704 8929 89885 exclusion phecode
627.2 Symptomatic menopause Genitourinary 1.01 0.866 – 1.18 0.877 181 1819 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.02 0.96 – 1.09 0.499 1096 11046 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1.06 0.944 – 1.2 0.314 308 3082 exclusion phecode
628 Ovarian cyst Genitourinary 1.07 1.04 – 1.11 7.54e-06 4624 47274 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.01 0.979 – 1.04 0.559 5199 36279 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.997 0.938 – 1.06 0.929 1128 11255 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.03 0.921 – 1.15 0.596 330 3283 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.999 0.953 – 1.05 0.977 1968 17310 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.03 0.956 – 1.1 0.479 863 8582 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1 0.945 – 1.06 0.943 1266 12260 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.02 0.972 – 1.06 0.49 2342 19894 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.995 0.916 – 1.08 0.907 617 6117 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.05 0.985 – 1.12 0.138 1080 10712 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 0.815 0.64 – 1.04 0.098 68 698 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.949 0.892 – 1.01 0.103 1104 11030 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.898 0.799 – 1.01 0.0719 305 3045 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.91 0.791 – 1.05 0.187 213 2139 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.878 0.742 – 1.04 0.131 152 1518 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 1 0.945 – 1.06 0.918 1246 12404 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.03 0.988 – 1.08 0.148 2219 20766 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.02 0.784 – 1.33 0.87 66 677 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.915 0.807 – 1.04 0.166 272 2743 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.984 0.808 – 1.2 0.872 113 1126 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.02 0.873 – 1.19 0.817 193 1912 exclusion phecode
650 Normal delivery Pregnancy Complications 0.983 0.937 – 1.03 0.475 1919 18898 exclusion phecode
651 Multiple gestation Pregnancy Complications 0.951 0.851 – 1.06 0.37 345 3446 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1.03 0.976 – 1.08 0.314 1710 16462 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.982 0.929 – 1.04 0.525 1398 13601 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.09 0.857 – 1.4 0.471 74 734 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.02 0.991 – 1.06 0.149 4298 29329 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.929 0.762 – 1.13 0.462 109 1077 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.993 0.95 – 1.04 0.759 2259 18327 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.97 0.886 – 1.06 0.504 529 5292 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 1 0.975 – 1.04 0.751 5298 29352 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.02 0.978 – 1.06 0.348 2545 21091 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.04 0.885 – 1.22 0.652 164 1622 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.05 0.927 – 1.2 0.418 262 2590 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.817 0.635 – 1.05 0.117 63 623 exclusion phecode
679 Complications of in utero procedures Dermatologic 1.03 0.768 – 1.38 0.844 53 528 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 0.997 0.973 – 1.02 0.807 7144 72042 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.02 0.938 – 1.11 0.616 559 5634 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.04 0.953 – 1.14 0.359 516 5195 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.996 0.969 – 1.02 0.781 5451 54878 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.998 0.971 – 1.03 0.89 5457 54938 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.996 0.969 – 1.02 0.773 5414 54509 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1 0.922 – 1.09 0.938 579 5966 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.02 0.961 – 1.08 0.557 1328 13389 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 0.964 0.923 – 1.01 0.0919 2277 22852 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.04 0.951 – 1.13 0.422 582 5821 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.01 0.904 – 1.12 0.886 360 3601 exclusion phecode
687 Symptoms affecting skin Dermatologic 1.06 0.974 – 1.16 0.168 544 5485 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.998 0.954 – 1.04 0.916 2118 21392 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.12 0.991 – 1.28 0.0686 281 2825 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.996 0.817 – 1.21 0.97 106 1067 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 0.995 0.957 – 1.03 0.792 2871 28778 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.01 0.983 – 1.04 0.458 5716 57297 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 1.17 0.929 – 1.48 0.181 71 710 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 1.11 0.846 – 1.44 0.463 53 530 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.946 0.787 – 1.14 0.552 120 1198 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.979 0.917 – 1.05 0.534 981 9804 exclusion phecode
694.1 Vitiligo Dermatologic 0.977 0.746 – 1.28 0.868 59 599 exclusion phecode
694.2 Other dyschromia Dermatologic 0.977 0.908 – 1.05 0.535 780 7782 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 0.912 0.755 – 1.1 0.339 115 1166 exclusion phecode
695 Erythematous conditions Dermatologic 1.02 0.98 – 1.07 0.294 2352 23702 exclusion phecode
695.1 Toxic erythema Dermatologic 0.913 0.748 – 1.11 0.37 108 1085 exclusion phecode
695.2 Bullous dermatoses Dermatologic 0.942 0.796 – 1.11 0.487 136 1363 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 0.856 0.674 – 1.09 0.202 57 567 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.03 0.814 – 1.31 0.788 72 727 exclusion phecode
695.3 Rosacea Dermatologic 1.08 0.96 – 1.22 0.196 308 3083 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.07 0.961 – 1.18 0.228 409 4087 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.972 0.811 – 1.17 0.759 130 1288 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.06 0.947 – 1.19 0.311 338 3389 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 1.05 0.974 – 1.13 0.207 765 7721 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 0.925 0.81 – 1.06 0.247 233 2349 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.784 0.62 – 0.992 0.0428 76 758 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 0.994 0.902 – 1.1 0.906 457 4658 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.997 0.955 – 1.04 0.904 2245 22442 exclusion phecode
696.4 Psoriasis Dermatologic 0.992 0.949 – 1.04 0.706 2191 21903 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.984 0.936 – 1.03 0.532 1673 16748 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 1.02 0.941 – 1.1 0.672 706 7027 exclusion phecode
697 Sarcoidosis Dermatologic 1 0.918 – 1.1 0.938 534 5353 exclusion phecode
698 Pruritus and related conditions Dermatologic 0.976 0.906 – 1.05 0.528 773 7793 exclusion phecode
700 Corns and callosities Dermatologic 0.996 0.885 – 1.12 0.951 288 2885 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.01 0.978 – 1.04 0.588 4635 46461 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.964 0.774 – 1.2 0.742 86 869 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.01 0.969 – 1.06 0.605 2333 23376 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 1.01 0.777 – 1.31 0.953 60 607 exclusion phecode
701.4 Keloid scar Dermatologic 0.999 0.867 – 1.15 0.992 216 2150 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 0.994 0.902 – 1.1 0.911 452 4547 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.28 1.04 – 1.59 0.0214 101 1017 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.964 0.937 – 0.991 0.00979 5408 54373 exclusion phecode
702.1 Actinic keratosis Dermatologic 1 0.961 – 1.04 0.964 2550 25737 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.922 0.888 – 0.956 1.43e-05 3061 30653 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.02 0.913 – 1.14 0.747 354 3527 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.981 0.919 – 1.05 0.568 960 9626 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.984 0.957 – 1.01 0.271 5250 52562 exclusion phecode
704.1 Alopecia Dermatologic 0.984 0.821 – 1.18 0.86 123 1263 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.87 0.69 – 1.1 0.24 76 757 exclusion phecode
705 Disorders of sweat glands Dermatologic 0.884 0.769 – 1.02 0.0815 226 2278 exclusion phecode
705.3 Hidradenitis Dermatologic 0.92 0.789 – 1.07 0.288 185 1860 exclusion phecode
705.8 Hyperhidrosis Dermatologic 0.967 0.889 – 1.05 0.43 588 5905 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 0.989 0.967 – 1.01 0.342 8286 82894 exclusion phecode
706.1 Acne Dermatologic 0.8 0.637 – 1.01 0.0558 78 776 exclusion phecode
706.2 Sebaceous cyst Dermatologic 0.994 0.972 – 1.02 0.595 8752 87572 exclusion phecode
707 Chronic ulcer of skin Dermatologic 0.995 0.95 – 1.04 0.817 1937 19600 exclusion phecode
707.1 Decubitus ulcer Dermatologic 0.974 0.91 – 1.04 0.436 901 9065 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.988 0.954 – 1.02 0.514 3414 34162 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.03 0.937 – 1.13 0.564 503 5045 exclusion phecode
709.3 Systemic sclerosis Dermatologic 1.11 0.951 – 1.31 0.181 176 1745 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.22 0.945 – 1.57 0.128 64 647 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.975 0.938 – 1.01 0.212 2702 27034 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.96 0.884 – 1.04 0.342 602 6021 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 0.966 0.886 – 1.05 0.44 556 5563 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.954 0.827 – 1.1 0.523 194 1943 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.972 0.877 – 1.08 0.584 398 3986 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 1.01 0.915 – 1.12 0.838 418 4219 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 0.955 0.854 – 1.07 0.413 326 3291 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 0.914 0.725 – 1.15 0.443 80 809 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.956 0.814 – 1.12 0.578 148 1495 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.09 0.854 – 1.38 0.499 65 668 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1 0.971 – 1.03 0.971 4792 48087 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.01 0.981 – 1.04 0.452 4337 43505 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.993 0.944 – 1.04 0.783 1652 16528 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.943 0.778 – 1.14 0.552 113 1122 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.995 0.917 – 1.08 0.903 617 6163 exclusion phecode
716 Other arthropathies Musculoskeletal 1 0.992 – 1.01 0.648 37285 264481 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.02 0.982 – 1.05 0.34 3487 34930 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.01 0.99 – 1.02 0.426 15475 154827 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1 0.991 – 1.01 0.682 35757 261420 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.01 0.948 – 1.07 0.806 1133 11425 exclusion phecode
720 Spinal stenosis Musculoskeletal 0.97 0.937 – 1 0.0715 3690 36943 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 0.998 0.975 – 1.02 0.863 7776 78011 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.993 0.964 – 1.02 0.611 5010 50255 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.08 0.929 – 1.25 0.327 188 1896 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 0.867 0.778 – 0.966 0.00961 350 3504 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 0.996 0.975 – 1.02 0.734 8943 89534 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.981 0.896 – 1.07 0.67 510 5101 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1 0.962 – 1.04 0.986 2820 28204 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 0.968 0.768 – 1.22 0.785 67 662 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1 0.973 – 1.04 0.81 4391 43976 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 0.981 0.897 – 1.07 0.676 516 5161 exclusion phecode
723.1 Torticollis Musculoskeletal 0.883 0.731 – 1.07 0.199 107 1065 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.01 0.967 – 1.06 0.607 2042 20438 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 0.984 0.888 – 1.09 0.754 400 4002 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.977 0.882 – 1.08 0.652 403 4031 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.18 0.901 – 1.54 0.231 62 629 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.02 0.967 – 1.07 0.507 1608 16088 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.01 0.99 – 1.02 0.45 14616 146170 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.998 0.977 – 1.02 0.865 9557 95565 exclusion phecode
726.2 Synoviopathy Musculoskeletal 1.04 0.929 – 1.16 0.5 333 3318 exclusion phecode
726.3 Bursitis Musculoskeletal 1.04 0.972 – 1.12 0.238 851 8557 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1 0.98 – 1.03 0.739 7299 73038 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.01 0.967 – 1.05 0.781 2727 27296 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.975 0.805 – 1.18 0.8 103 1022 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.02 0.984 – 1.06 0.274 3090 30947 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.972 0.893 – 1.06 0.514 583 5838 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.04 0.932 – 1.16 0.479 353 3508 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.973 0.824 – 1.15 0.748 143 1427 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.998 0.965 – 1.03 0.909 3671 36720 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.04 0.936 – 1.15 0.49 411 4101 exclusion phecode
728.7 Fasciitis Musculoskeletal 1 0.971 – 1.04 0.842 3796 37974 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.999 0.965 – 1.03 0.961 3471 34724 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.02 0.99 – 1.04 0.212 5964 60082 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.975 0.913 – 1.04 0.45 996 10006 exclusion phecode
729.3 Panniculitis Musculoskeletal 1.16 0.94 – 1.44 0.165 101 1008 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.977 0.861 – 1.11 0.722 268 2744 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.966 0.848 – 1.1 0.606 253 2594 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.951 0.866 – 1.05 0.302 465 4663 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.973 0.845 – 1.12 0.698 206 2058 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.914 0.709 – 1.18 0.49 57 569 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.987 0.94 – 1.04 0.598 1766 17731 exclusion phecode
733.2 Cyst of bone Musculoskeletal 0.95 0.847 – 1.07 0.38 311 3101 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.03 0.939 – 1.12 0.557 538 5378 exclusion phecode
733.6 Costochondritis Musculoskeletal 0.967 0.81 – 1.15 0.712 128 1272 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.987 0.931 – 1.05 0.649 1223 12276 exclusion phecode
733.9 Chondromalacia Musculoskeletal 0.894 0.742 – 1.08 0.238 121 1203 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1 0.982 – 1.02 0.786 9550 95543 exclusion phecode
735.1 Flat foot Musculoskeletal 0.951 0.822 – 1.1 0.495 188 1899 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 1.02 0.988 – 1.05 0.24 5041 50421 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.02 0.977 – 1.07 0.314 1916 19213 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 1.02 0.966 – 1.07 0.515 1547 15448 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.999 0.974 – 1.02 0.942 6604 66049 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 0.989 0.94 – 1.04 0.687 1619 16225 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.05 0.917 – 1.2 0.475 247 2468 exclusion phecode
737 Curvature of spine Musculoskeletal 0.958 0.901 – 1.02 0.169 1119 11237 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.952 0.894 – 1.01 0.13 1055 10567 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.01 0.959 – 1.05 0.809 1894 18967 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.01 0.953 – 1.06 0.851 1504 15072 exclusion phecode
739 Contracture of joint Musculoskeletal 0.949 0.865 – 1.04 0.264 483 4869 exclusion phecode
740 Osteoarthrosis Musculoskeletal 0.997 0.984 – 1.01 0.584 27569 230737 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.992 0.976 – 1.01 0.307 17345 168730 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.981 0.96 – 1 0.0899 8941 89391 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.03 0.926 – 1.16 0.545 346 3463 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.06 0.977 – 1.16 0.155 592 5944 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.01 0.987 – 1.02 0.553 12185 122272 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.02 0.988 – 1.06 0.193 3553 35540 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 1.03 0.841 – 1.26 0.786 102 1017 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.02 0.935 – 1.1 0.706 612 6119 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.959 0.811 – 1.13 0.622 153 1533 exclusion phecode
741.4 Joint effusions Musculoskeletal 1.04 0.983 – 1.1 0.177 1414 14153 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.06 0.875 – 1.29 0.534 110 1098 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 1.3 0.976 – 1.74 0.0729 54 532 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.965 0.928 – 1 0.0696 2838 28356 exclusion phecode
742.1 Loose body in joint Musculoskeletal 0.936 0.84 – 1.04 0.234 333 3329 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1 0.818 – 1.23 0.984 95 955 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 0.903 0.825 – 0.989 0.0278 498 4980 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.987 0.943 – 1.03 0.588 1990 19863 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1 0.98 – 1.03 0.747 7493 75281 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1 0.977 – 1.03 0.845 6339 63707 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 0.997 0.969 – 1.02 0.811 5494 55231 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1.02 0.93 – 1.11 0.714 523 5264 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 0.94 0.859 – 1.03 0.179 508 5155 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.04 0.971 – 1.12 0.25 812 8107 exclusion phecode
745 Pain in joint Musculoskeletal 1.02 1 – 1.05 0.0551 7941 79486 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.02 0.979 – 1.06 0.383 2789 27975 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.01 0.971 – 1.05 0.586 2618 26247 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.979 0.898 – 1.07 0.62 583 5815 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1 0.878 – 1.14 0.991 234 2352 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.01 0.959 – 1.06 0.791 1810 18150 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.07 0.915 – 1.26 0.388 164 1677 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.04 0.78 – 1.39 0.78 51 507 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.886 0.788 – 0.995 0.0414 303 3015 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 1.03 0.949 – 1.11 0.504 681 6850 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.04 0.927 – 1.16 0.511 325 3256 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.978 0.843 – 1.14 0.773 189 1906 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.05 0.937 – 1.17 0.429 353 3556 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.997 0.869 – 1.14 0.965 223 2248 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.17 0.969 – 1.41 0.104 116 1172 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.976 0.926 – 1.03 0.363 1520 15243 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.982 0.908 – 1.06 0.65 691 6911 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.991 0.9 – 1.09 0.853 452 4525 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.993 0.865 – 1.14 0.919 222 2217 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.992 0.924 – 1.07 0.832 832 8365 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 1.04 0.939 – 1.15 0.473 421 4233 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.943 0.843 – 1.05 0.3 332 3339 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.987 0.88 – 1.11 0.819 327 3295 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1 0.879 – 1.14 0.997 252 2547 exclusion phecode
752.11 Spina bifida Congenital Anomalies 1.05 0.91 – 1.22 0.495 207 2098 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.98 0.784 – 1.22 0.858 78 777 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.997 0.83 – 1.2 0.978 127 1267 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.07 0.846 – 1.36 0.564 76 759 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.02 0.839 – 1.24 0.834 108 1096 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.02 0.925 – 1.13 0.652 423 4255 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 1 0.865 – 1.16 0.983 207 2078 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.951 0.803 – 1.13 0.557 160 1614 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.01 0.823 – 1.24 0.914 106 1064 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.02 0.933 – 1.11 0.709 584 5856 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.17 0.927 – 1.47 0.188 81 807 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.956 0.865 – 1.06 0.375 432 4339 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.11 0.941 – 1.32 0.21 147 1702 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.21 0.929 – 1.57 0.158 60 825 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.06 0.924 – 1.23 0.387 212 2153 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.1 0.89 – 1.36 0.382 96 955 exclusion phecode
760 Back pain Symptoms 1.01 0.989 – 1.03 0.392 11067 110933 exclusion phecode
761 Cervicalgia Symptoms 1 0.954 – 1.05 0.95 1779 17834 exclusion phecode
764 Sciatica Symptoms 1.02 0.98 – 1.07 0.298 2365 23646 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.957 0.902 – 1.02 0.146 1168 11685 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 0.98 0.905 – 1.06 0.618 628 6295 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.06 0.988 – 1.14 0.103 865 8662 exclusion phecode
771.1 Swelling of limb Symptoms 1.03 0.996 – 1.06 0.0849 4576 46170 exclusion phecode
772 Symptoms of the muscles Symptoms 1.11 1.03 – 1.2 0.0101 654 6558 exclusion phecode
773 Pain in limb Symptoms 1 0.974 – 1.03 0.988 6177 61969 exclusion phecode
780 Hypothermia/Chills Symptoms 0.897 0.765 – 1.05 0.179 171 1714 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.01 0.967 – 1.06 0.566 1862 18658 exclusion phecode
782.3 Edema Symptoms 1.02 0.966 – 1.07 0.529 1614 16395 exclusion phecode
782.6 Pallor and flushing Symptoms 0.996 0.858 – 1.16 0.958 174 1743 exclusion phecode
783 Fever of unknown origin Symptoms 1.02 0.99 – 1.06 0.178 3826 38989 exclusion phecode
785 Abdominal pain Symptoms 1 0.993 – 1.01 0.525 39766 300783 exclusion phecode
788 Syncope and collapse Symptoms 1.01 0.988 – 1.03 0.382 9025 90554 exclusion phecode
789 Nausea and vomiting Symptoms 1 0.986 – 1.02 0.615 11364 115403 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.05 0.884 – 1.23 0.605 150 1497 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.14 0.918 – 1.41 0.238 84 835 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.02 0.993 – 1.04 0.161 6309 63539 exclusion phecode
791 Gangrene Symptoms 1.03 0.939 – 1.12 0.574 545 5487 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1.11 0.89 – 1.38 0.36 95 966 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.965 0.808 – 1.15 0.696 131 1338 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 0.974 0.893 – 1.06 0.548 560 5624 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.06 0.872 – 1.29 0.554 119 1191 exclusion phecode
797 Shock Symptoms 0.889 0.76 – 1.04 0.144 156 1557 exclusion phecode
797.1 Cardiogenic shock Symptoms 0.818 0.673 – 0.995 0.0439 102 1019 exclusion phecode
798 Malaise and fatigue Symptoms 1.02 0.986 – 1.06 0.227 3364 33981 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 0.957 0.879 – 1.04 0.32 588 5885 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 0.997 0.973 – 1.02 0.823 6995 70053 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.983 0.936 – 1.03 0.478 1798 18070 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.891 0.763 – 1.04 0.148 169 1686 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.01 0.968 – 1.06 0.604 2146 21523 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.963 0.895 – 1.04 0.321 766 7632 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.02 0.972 – 1.06 0.505 2192 21961 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.01 0.962 – 1.06 0.703 1825 18283 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 0.987 0.915 – 1.06 0.734 715 7164 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.997 0.975 – 1.02 0.803 8250 82520 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 0.989 0.94 – 1.04 0.655 1685 16802 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1 0.976 – 1.03 0.744 5188 51898 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.995 0.944 – 1.05 0.862 1512 15168 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.999 0.964 – 1.04 0.95 3328 33295 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.04 0.979 – 1.1 0.219 1352 13524 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.01 0.941 – 1.09 0.744 772 7730 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.05 0.991 – 1.11 0.0998 1295 12958 exclusion phecode
817 Concussion Injuries & Poisonings 1.02 0.896 – 1.16 0.773 243 2420 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.01 0.923 – 1.1 0.835 519 5206 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.03 0.992 – 1.07 0.126 2947 29545 exclusion phecode
823 Torus fracture Injuries & Poisonings 0.992 0.944 – 1.04 0.756 1663 16662 exclusion phecode
830 Dislocation Injuries & Poisonings 0.989 0.945 – 1.03 0.615 2081 20831 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.994 0.978 – 1.01 0.488 15185 151825 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.974 0.891 – 1.06 0.556 525 5260 exclusion phecode
840 Sprains and strains Injuries & Poisonings 1.02 0.933 – 1.12 0.617 469 4684 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.02 0.995 – 1.05 0.105 5196 52463 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.995 0.842 – 1.18 0.956 156 1559 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.02 0.928 – 1.12 0.689 480 5001 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.03 0.984 – 1.08 0.191 1814 18201 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.996 0.94 – 1.05 0.878 1230 12379 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.986 0.95 – 1.02 0.439 3141 31484 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.01 0.97 – 1.04 0.755 3235 32498 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.39 1.08 – 1.78 0.0104 67 679 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.04 1 – 1.08 0.0265 3495 34973 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.944 0.833 – 1.07 0.369 272 2710 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1.1 0.952 – 1.28 0.19 196 1946 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.03 0.991 – 1.07 0.137 2897 29014 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.09 0.948 – 1.25 0.227 219 2193 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.988 0.777 – 1.26 0.922 68 678 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.01 0.976 – 1.04 0.642 4050 40552 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.04 0.789 – 1.37 0.782 53 530 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.03 0.834 – 1.27 0.785 90 898 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.979 0.841 – 1.14 0.788 178 1781 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 0.98 0.892 – 1.08 0.682 475 4738 exclusion phecode
873 Broken tooth Injuries & Poisonings 1.04 0.91 – 1.19 0.575 228 2284 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.12 0.954 – 1.31 0.17 169 1705 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 0.925 0.787 – 1.09 0.346 157 1562 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 0.958 0.906 – 1.01 0.139 1310 13105 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.01 0.98 – 1.04 0.492 4238 42543 exclusion phecode
916 Contusion Injuries & Poisonings 1.03 0.978 – 1.09 0.243 1445 14472 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.952 0.817 – 1.11 0.533 178 1797 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.993 0.894 – 1.1 0.896 387 3885 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.982 0.862 – 1.12 0.783 252 2518 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.983 0.94 – 1.03 0.459 2077 20896 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.18 1.02 – 1.35 0.023 221 2241 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.868 0.708 – 1.06 0.172 100 1033 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.05 0.964 – 1.15 0.256 548 5488 exclusion phecode
947 Urticaria Injuries & Poisonings 1 0.899 – 1.12 0.978 369 3694 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.1 0.993 – 1.23 0.0676 393 3978 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.11 1 – 1.22 0.0485 421 4211 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.933 0.823 – 1.06 0.277 268 2685 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.01 0.917 – 1.1 0.914 487 4923 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.12 0.848 – 1.48 0.425 52 554 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.943 0.75 – 1.18 0.612 73 738 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.01 0.993 – 1.02 0.309 17935 180432 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.01 0.995 – 1.03 0.189 15713 158012 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 0.982 0.888 – 1.09 0.727 410 4174 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.01 0.942 – 1.08 0.76 861 8664 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.06 0.955 – 1.18 0.267 367 3695 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.08 0.972 – 1.2 0.152 360 3626 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.988 0.858 – 1.14 0.862 215 2218 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.04 0.916 – 1.17 0.58 279 2823 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.02 0.902 – 1.16 0.733 273 2763 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.992 0.966 – 1.02 0.558 6026 60632 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.03 0.965 – 1.09 0.402 1125 11397 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.02 0.927 – 1.12 0.712 475 4751 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.924 0.835 – 1.02 0.122 403 4035 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.05 0.956 – 1.14 0.324 510 5099 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.989 0.908 – 1.08 0.8 575 5817 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.03 0.987 – 1.08 0.164 1939 19457 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.958 0.825 – 1.11 0.568 188 1904 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.04 0.921 – 1.18 0.509 270 2708 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.91 0.735 – 1.13 0.389 84 846 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.06 0.869 – 1.29 0.566 108 1074 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.2 0.98 – 1.47 0.0779 101 1012 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.934 0.726 – 1.2 0.596 64 640 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.798 0.619 – 1.03 0.0819 58 578 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.2 1.04 – 1.38 0.0104 226 2332 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.11 1.03 – 1.2 0.00663 687 6944 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.959 0.83 – 1.11 0.566 200 1992 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.05 0.801 – 1.38 0.719 62 620 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.05 0.861 – 1.27 0.645 104 1047 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.969 0.798 – 1.18 0.75 111 1123 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.12 0.891 – 1.41 0.332 89 887 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 0.987 0.951 – 1.02 0.487 3045 31026 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.01 0.97 – 1.05 0.694 2958 30182 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.01 0.97 – 1.05 0.694 2958 30182 exclusion phecode
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