Departments of Anesthesiology and Biostatistics | University of Michigan

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Cancer PRSweb

Compare evaluated PRS models, inspect score-level performance, and follow results into PheWAS analyses.

Scores Cancer of prostate UK Biobank (UKB) PheWAS analysis

Cancer of prostate — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID prsweb-phecode185-pca-practical-pt-ukb-20200608Legacy P&TP&TSchumacher FR et al. 2019

Evaluation cohort: UK Biobank (UKB).

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129 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 0.987 0.965 – 1.01 0.235 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 0.999 0.96 – 1.04 0.95 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.05 0.966 – 1.13 0.267 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 0.9 0.838 – 0.966 0.00351 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 0.814 0.619 – 1.07 0.14 55 550 all phecode
010 Tuberculosis Infectious Diseases 0.861 0.736 – 1.01 0.0633 166 1659 all phecode
038 Septicemia Infectious Diseases 1.03 0.995 – 1.06 0.0932 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 0.999 0.932 – 1.07 0.98 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.05 0.957 – 1.15 0.315 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 1.01 0.995 – 1.03 0.146 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.02 0.986 – 1.06 0.236 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 0.972 0.924 – 1.02 0.279 1641 16433 all phecode
041.4 E. coli Infectious Diseases 1.02 0.979 – 1.06 0.378 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 1.01 0.915 – 1.12 0.797 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.04 0.84 – 1.3 0.702 95 949 all phecode
054 Herpes simplex Infectious Diseases 0.942 0.817 – 1.09 0.407 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 0.968 0.889 – 1.05 0.446 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 1.13 0.887 – 1.45 0.315 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 1 0.838 – 1.19 0.997 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 0.964 0.85 – 1.09 0.564 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.09 0.967 – 1.23 0.155 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 0.933 0.844 – 1.03 0.178 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.02 0.867 – 1.2 0.801 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.07 0.891 – 1.29 0.47 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 1.03 0.965 – 1.1 0.384 1004 10036 all phecode
079 Viral infection Infectious Diseases 0.984 0.946 – 1.02 0.411 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 1.26 0.983 – 1.61 0.0685 64 640 all phecode
080 Postoperative infection Infectious Diseases 1.03 0.999 – 1.06 0.0555 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 0.972 0.932 – 1.01 0.178 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.02 0.812 – 1.27 0.88 71 709 all phecode
1000 Burns Injuries & Poisonings 1.05 0.964 – 1.14 0.265 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 1.06 1 – 1.13 0.0447 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 0.998 0.971 – 1.03 0.891 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.05 0.929 – 1.18 0.444 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 0.989 0.937 – 1.04 0.696 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 0.88 0.774 – 1 0.0517 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 0.938 0.823 – 1.07 0.334 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 0.977 0.916 – 1.04 0.479 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 1.01 0.985 – 1.03 0.545 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 0.987 0.961 – 1.01 0.325 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.992 0.971 – 1.01 0.456 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 0.916 0.747 – 1.12 0.403 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.02 0.907 – 1.15 0.736 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.943 0.745 – 1.19 0.623 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 1.01 0.98 – 1.04 0.491 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1 0.987 – 1.02 0.694 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.989 0.874 – 1.12 0.865 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 1.02 0.902 – 1.16 0.724 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.14 0.895 – 1.44 0.293 74 756 all phecode
110.12 Althete's foot Infectious Diseases 1.05 0.88 – 1.24 0.613 141 1410 all phecode
112 Candidiasis Infectious Diseases 0.985 0.942 – 1.03 0.516 2126 21275 all phecode
117 Mycoses Infectious Diseases 1.05 0.926 – 1.18 0.47 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 1.09 0.937 – 1.28 0.258 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 1.12 0.899 – 1.4 0.306 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 1.21 0.957 – 1.53 0.111 69 689 all phecode
134 Helminthiases Infectious Diseases 1.08 0.903 – 1.3 0.386 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.09 0.898 – 1.33 0.372 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.883 0.763 – 1.02 0.0931 205 2050 all phecode
145 Cancer of mouth Neoplasms 0.969 0.893 – 1.05 0.448 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 0.96 0.856 – 1.08 0.491 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 0.915 0.747 – 1.12 0.389 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.12 0.845 – 1.49 0.425 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1 0.925 – 1.09 0.938 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 1.02 0.893 – 1.15 0.819 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 1.03 0.909 – 1.17 0.617 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 1.12 0.873 – 1.43 0.379 57 570 all phecode
150 Cancer of esophagus Neoplasms 1.04 0.965 – 1.12 0.316 762 7630 all phecode
151 Cancer of stomach Neoplasms 1.01 0.924 – 1.1 0.873 569 5696 all phecode
153 Colorectal cancer Neoplasms 0.995 0.965 – 1.03 0.753 4580 45799 all phecode
153.2 Colon cancer Neoplasms 1 0.966 – 1.04 0.895 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.991 0.948 – 1.04 0.676 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.97 0.876 – 1.08 0.566 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.86 0.728 – 1.02 0.0755 158 1580 all phecode
157 Pancreatic cancer Neoplasms 1.03 0.947 – 1.11 0.537 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.06 0.992 – 1.12 0.0855 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.998 0.971 – 1.03 0.888 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.07 0.925 – 1.24 0.363 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.01 0.877 – 1.17 0.857 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.12 0.967 – 1.29 0.131 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 0.945 0.724 – 1.23 0.679 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 1 0.962 – 1.04 1 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 0.978 0.937 – 1.02 0.325 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.854 0.776 – 0.941 0.00145 437 4364 all phecode
170.1 Bone cancer Neoplasms 0.911 0.76 – 1.09 0.318 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 0.812 0.726 – 0.907 0.000241 331 3303 all phecode
172 Skin cancer Neoplasms 1.01 0.995 – 1.03 0.17 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.01 0.972 – 1.05 0.595 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 1.01 0.972 – 1.05 0.601 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1.02 0.998 – 1.04 0.0746 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 0.988 0.913 – 1.07 0.776 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.08 0.929 – 1.26 0.313 181 1818 all phecode
174 Breast cancer Neoplasms 1.01 0.992 – 1.03 0.259 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 1.01 0.991 – 1.03 0.308 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.01 0.987 – 1.03 0.526 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.18 0.974 – 1.42 0.0926 115 1148 all phecode
175 Acquired absence of breast Neoplasms 1.02 0.975 – 1.06 0.445 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 1.01 0.965 – 1.05 0.721 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 1.01 0.895 – 1.14 0.851 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.999 0.955 – 1.04 0.958 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 1.04 0.985 – 1.1 0.147 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 1.01 0.958 – 1.07 0.659 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.02 0.956 – 1.09 0.514 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.03 0.964 – 1.1 0.375 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.01 0.899 – 1.13 0.872 305 3049 all phecode
185 Cancer of prostate Neoplasms 1.99 1.93 – 2.04 6.41e-510 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 1.04 0.949 – 1.15 0.373 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.991 0.78 – 1.26 0.941 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.982 0.871 – 1.11 0.766 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.03 0.854 – 1.25 0.737 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.06 1.02 – 1.09 0.000769 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.981 0.921 – 1.04 0.551 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.971 0.911 – 1.04 0.371 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.04 0.812 – 1.33 0.757 66 660 all phecode
189.2 Cancer of bladder Neoplasms 1.03 0.986 – 1.07 0.198 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.01 0.965 – 1.05 0.706 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.1 0.922 – 1.3 0.299 144 1439 all phecode
190 Cancer of eye Neoplasms 1.02 0.872 – 1.19 0.833 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.97 0.898 – 1.05 0.447 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1 0.92 – 1.09 0.964 566 5650 all phecode
191.11 Cancer of brain Neoplasms 0.987 0.904 – 1.08 0.778 525 5240 all phecode
193 Thyroid cancer Neoplasms 1.03 0.922 – 1.15 0.602 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 1.03 0.843 – 1.26 0.761 95 949 all phecode
195 Cancer, suspected or other Neoplasms 1.12 1.1 – 1.13 1.8e-42 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.12 1.1 – 1.14 1.14e-43 16267 159497 all phecode
197 Chemotherapy Neoplasms 0.999 0.985 – 1.01 0.928 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 1.05 1.02 – 1.07 2.26e-05 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.03 1 – 1.06 0.0487 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.05 1 – 1.09 0.0423 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.06 1.01 – 1.12 0.0246 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.02 0.982 – 1.06 0.283 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.08 1.01 – 1.16 0.0328 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.18 1.13 – 1.24 7.71e-14 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.13 0.976 – 1.31 0.103 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 0.985 0.933 – 1.04 0.591 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 1.08 0.88 – 1.34 0.446 95 950 all phecode
200 Myeloproliferative disease Neoplasms 1.07 0.999 – 1.14 0.0535 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 1.02 0.92 – 1.13 0.691 387 3867 all phecode
201 Hodgkin's disease Neoplasms 1.04 0.92 – 1.18 0.519 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.982 0.94 – 1.03 0.404 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.979 0.933 – 1.03 0.385 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 0.888 0.797 – 0.99 0.0328 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 1.03 0.943 – 1.12 0.535 581 5824 all phecode
204 Leukemia Neoplasms 1.01 0.959 – 1.06 0.733 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 0.976 0.896 – 1.06 0.581 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.82 0.63 – 1.07 0.141 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.01 0.923 – 1.11 0.814 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 0.967 0.879 – 1.06 0.484 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.938 0.837 – 1.05 0.265 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.07 0.905 – 1.27 0.415 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 1.03 0.945 – 1.12 0.491 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 1.02 1.01 – 1.04 0.00195 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.941 0.881 – 1 0.0698 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.992 0.964 – 1.02 0.591 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.997 0.894 – 1.11 0.957 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.988 0.881 – 1.11 0.836 318 3187 all phecode
214 Lipoma Neoplasms 0.999 0.973 – 1.03 0.932 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.01 0.984 – 1.05 0.367 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.02 0.956 – 1.08 0.611 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 0.99 0.967 – 1.01 0.398 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.15 1.06 – 1.25 0.000569 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.18 1.08 – 1.28 0.000131 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 0.999 0.978 – 1.02 0.904 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 0.999 0.979 – 1.02 0.898 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.03 0.925 – 1.15 0.576 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 1.02 0.969 – 1.08 0.421 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.03 0.899 – 1.19 0.639 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 1.03 0.879 – 1.22 0.686 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.966 0.826 – 1.13 0.664 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 1.17 0.982 – 1.4 0.078 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.11 0.864 – 1.42 0.419 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.02 0.945 – 1.09 0.665 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.01 0.939 – 1.09 0.758 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.24 0.949 – 1.62 0.115 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.993 0.877 – 1.12 0.91 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.05 0.975 – 1.12 0.209 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.07 0.924 – 1.24 0.368 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.02 0.92 – 1.14 0.658 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.07 0.953 – 1.2 0.257 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.994 0.944 – 1.05 0.821 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.989 0.948 – 1.03 0.611 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.986 0.907 – 1.07 0.732 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.989 0.929 – 1.05 0.731 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.968 0.881 – 1.06 0.495 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.01 0.928 – 1.09 0.89 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.927 0.884 – 0.973 0.00198 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 0.899 0.815 – 0.991 0.032 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.05 0.846 – 1.29 0.678 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 0.848 0.712 – 1.01 0.0656 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 0.981 0.965 – 0.998 0.0319 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1 0.941 – 1.07 0.971 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.967 0.796 – 1.17 0.736 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.981 0.964 – 0.998 0.031 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 0.845 0.748 – 0.955 0.00697 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.873 0.759 – 1 0.0577 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.857 0.743 – 0.989 0.0341 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 0.923 0.834 – 1.02 0.123 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 0.994 0.979 – 1.01 0.398 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.994 0.956 – 1.03 0.778 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.02 0.889 – 1.16 0.802 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.866 0.687 – 1.09 0.221 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.93 0.847 – 1.02 0.128 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.07 0.907 – 1.25 0.442 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.992 0.977 – 1.01 0.29 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.841 0.691 – 1.02 0.0839 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.936 0.811 – 1.08 0.372 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.961 0.9 – 1.03 0.229 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.02 0.935 – 1.12 0.618 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.06 0.981 – 1.15 0.139 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.14 1.01 – 1.29 0.0398 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.01 0.916 – 1.12 0.791 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.942 0.785 – 1.13 0.517 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.974 0.874 – 1.08 0.63 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.959 0.907 – 1.01 0.145 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.06 0.989 – 1.13 0.102 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.991 0.924 – 1.06 0.792 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.973 0.904 – 1.05 0.462 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.03 0.864 – 1.22 0.77 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.03 0.954 – 1.12 0.429 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.02 0.882 – 1.19 0.765 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.01 0.819 – 1.23 0.959 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.16 1.02 – 1.32 0.0225 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.934 0.752 – 1.16 0.536 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.937 0.794 – 1.1 0.435 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.997 0.919 – 1.08 0.943 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.865 0.742 – 1.01 0.0653 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.852 0.694 – 1.04 0.124 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.836 0.664 – 1.05 0.126 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.06 0.95 – 1.18 0.304 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.05 0.945 – 1.17 0.352 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.1 0.965 – 1.26 0.152 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.15 0.997 – 1.32 0.0557 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 0.931 0.794 – 1.09 0.381 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.935 0.794 – 1.1 0.418 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.04 0.85 – 1.26 0.721 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 0.917 0.776 – 1.09 0.315 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.06 0.917 – 1.22 0.435 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 1.35 1.01 – 1.8 0.0397 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 1.04 0.972 – 1.12 0.24 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.04 0.979 – 1.1 0.204 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.06 0.985 – 1.15 0.114 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.959 0.871 – 1.06 0.396 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.765 0.605 – 0.968 0.0257 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.897 0.785 – 1.02 0.108 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 0.973 0.871 – 1.09 0.623 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.989 0.879 – 1.11 0.851 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1 0.884 – 1.14 0.955 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.01 0.873 – 1.17 0.873 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.37 1.13 – 1.66 0.00122 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.07 0.837 – 1.36 0.604 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.02 0.864 – 1.2 0.826 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.949 0.796 – 1.13 0.553 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.02 1 – 1.03 0.00704 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.02 1 – 1.03 0.00632 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.01 1 – 1.03 0.0191 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.78 0.6 – 1.01 0.0637 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.1 0.935 – 1.29 0.256 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.06 0.922 – 1.21 0.425 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.01 0.979 – 1.05 0.481 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 1.01 0.979 – 1.05 0.425 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.11 0.913 – 1.35 0.297 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.948 0.873 – 1.03 0.206 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.961 0.881 – 1.05 0.365 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.01 0.969 – 1.06 0.572 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 1.03 0.953 – 1.12 0.431 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 0.957 0.861 – 1.06 0.419 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.998 0.94 – 1.06 0.946 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.05 0.892 – 1.23 0.565 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.02 0.993 – 1.04 0.165 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.02 0.986 – 1.05 0.266 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.05 0.917 – 1.19 0.5 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.02 0.971 – 1.07 0.459 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.03 0.968 – 1.11 0.32 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.02 0.964 – 1.07 0.524 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.08 1.02 – 1.14 0.0138 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 1.07 1 – 1.14 0.0424 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 1.11 0.921 – 1.33 0.275 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.02 0.98 – 1.06 0.354 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 0.952 0.864 – 1.05 0.313 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 1.1 0.916 – 1.32 0.31 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 0.979 0.915 – 1.05 0.549 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.967 0.869 – 1.08 0.539 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.901 0.786 – 1.03 0.132 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.08 0.829 – 1.4 0.58 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.01 0.988 – 1.03 0.461 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 1.01 0.99 – 1.03 0.341 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 1.12 0.898 – 1.4 0.312 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.832 0.65 – 1.06 0.143 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.994 0.874 – 1.13 0.926 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 0.911 0.791 – 1.05 0.193 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.904 0.759 – 1.08 0.258 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.22 1.07 – 1.38 0.00274 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 0.997 0.974 – 1.02 0.79 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.994 0.971 – 1.02 0.637 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.03 0.935 – 1.14 0.547 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 0.991 0.932 – 1.05 0.78 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 0.995 0.934 – 1.06 0.871 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 1.03 0.96 – 1.12 0.37 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.94 0.802 – 1.1 0.446 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 0.881 0.755 – 1.03 0.109 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 0.862 0.661 – 1.12 0.273 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.18 0.994 – 1.4 0.0585 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.35 1.03 – 1.77 0.0311 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.06 0.845 – 1.33 0.614 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.09 0.909 – 1.3 0.356 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.02 0.835 – 1.25 0.841 103 1059 all phecode
284 Aplastic anemia Hematopoietic 0.974 0.883 – 1.07 0.597 435 4357 all phecode
285 Other anemias Hematopoietic 1 0.983 – 1.02 0.86 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.989 0.874 – 1.12 0.864 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 0.925 0.856 – 1 0.0489 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.962 0.87 – 1.06 0.448 414 4147 all phecode
286 Coagulation defects Hematopoietic 0.975 0.912 – 1.04 0.468 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 1 0.91 – 1.1 0.969 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 0.989 0.801 – 1.22 0.918 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.08 0.959 – 1.22 0.2 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 0.951 0.74 – 1.22 0.694 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.921 0.735 – 1.15 0.473 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.952 0.859 – 1.06 0.353 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.996 0.947 – 1.05 0.864 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.06 0.89 – 1.27 0.5 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 1.43 1.08 – 1.88 0.0111 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 0.984 0.934 – 1.04 0.541 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 0.995 0.9 – 1.1 0.913 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.936 0.748 – 1.17 0.566 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 1 0.968 – 1.03 0.97 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 1 0.964 – 1.04 0.979 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 1 0.964 – 1.04 0.991 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 0.943 0.74 – 1.2 0.632 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.04 0.966 – 1.11 0.312 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.06 0.94 – 1.2 0.341 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 1.02 0.979 – 1.06 0.357 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 1.05 0.96 – 1.15 0.286 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 0.997 0.882 – 1.13 0.961 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 0.935 0.754 – 1.16 0.544 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.997 0.952 – 1.05 0.915 1929 19281 all phecode
290.1 Dementias Mental Disorders 0.986 0.924 – 1.05 0.675 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 0.924 0.836 – 1.02 0.119 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 1.05 0.91 – 1.21 0.504 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.01 0.935 – 1.1 0.776 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.07 0.847 – 1.36 0.561 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.05 0.977 – 1.13 0.19 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.04 0.87 – 1.24 0.68 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.11 0.983 – 1.25 0.0923 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 1.03 0.931 – 1.13 0.594 436 4376 all phecode
292 Neurological disorders Mental Disorders 1.05 1.02 – 1.09 0.000674 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.05 1 – 1.11 0.0503 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 1.15 0.994 – 1.33 0.0607 190 1907 all phecode
292.3 Memory loss Mental Disorders 1.06 0.978 – 1.14 0.164 696 6978 all phecode
292.4 Altered mental status Mental Disorders 1.07 1.03 – 1.12 0.00214 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 0.97 0.862 – 1.09 0.619 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 1.03 0.985 – 1.08 0.188 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.02 0.95 – 1.09 0.616 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1 0.936 – 1.08 0.904 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 1.04 0.955 – 1.13 0.367 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 0.952 0.818 – 1.11 0.524 178 1780 all phecode
295.3 Psychosis Mental Disorders 0.966 0.826 – 1.13 0.669 169 1710 all phecode
296 Mood disorders Mental Disorders 1.01 0.99 – 1.03 0.367 12372 123822 all phecode
296.1 Bipolar Mental Disorders 1.02 0.959 – 1.09 0.512 1059 10599 all phecode
296.2 Depression Mental Disorders 1.01 0.988 – 1.03 0.459 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 1 0.902 – 1.12 0.929 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.998 0.89 – 1.12 0.975 311 3070 all phecode
300 Anxiety disorders Mental Disorders 1 0.976 – 1.03 0.969 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 0.999 0.974 – 1.03 0.949 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1.01 0.854 – 1.19 0.933 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.03 0.952 – 1.11 0.479 707 7065 all phecode
300.13 Phobia Mental Disorders 1 0.913 – 1.1 0.972 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.07 0.897 – 1.27 0.462 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 1.15 0.874 – 1.51 0.32 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 0.992 0.825 – 1.19 0.935 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.02 0.841 – 1.24 0.826 113 1129 all phecode
301 Personality disorders Mental Disorders 1.05 0.939 – 1.18 0.39 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.1 0.913 – 1.33 0.313 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 1.13 0.995 – 1.27 0.0609 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.963 0.875 – 1.06 0.436 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 0.971 0.871 – 1.08 0.597 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 0.922 0.766 – 1.11 0.396 123 1229 all phecode
304 Adjustment reaction Mental Disorders 1.05 0.928 – 1.18 0.456 293 2936 all phecode
305.2 Eating disorder Mental Disorders 1.22 0.976 – 1.51 0.0811 90 900 all phecode
306 Other mental disorder Mental Disorders 1.01 0.996 – 1.02 0.174 28056 230087 all phecode
306.9 Tension headache Mental Disorders 1.06 0.947 – 1.19 0.302 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 1.09 0.871 – 1.37 0.449 76 770 all phecode
313.3 Autism Mental Disorders 1.05 0.801 – 1.37 0.729 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 1.08 0.966 – 1.2 0.185 351 3517 all phecode
315.1 Learning disorder Mental Disorders 0.982 0.836 – 1.15 0.822 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 0.933 0.754 – 1.15 0.523 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 1 0.973 – 1.03 0.956 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.808 0.626 – 1.04 0.101 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 1.01 0.987 – 1.02 0.569 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 1.01 0.99 – 1.03 0.311 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 0.958 0.893 – 1.03 0.234 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 1.01 0.993 – 1.02 0.322 19359 185465 all phecode
320 Meningitis Neurological 1.01 0.915 – 1.11 0.884 444 4447 all phecode
323 Encephalitis Neurological 1.03 0.921 – 1.15 0.609 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 1.37 1.09 – 1.74 0.00811 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 0.966 0.858 – 1.09 0.566 292 2916 all phecode
327 Sleep disorders Neurological 1.02 0.959 – 1.08 0.556 1164 11659 all phecode
327.3 Sleep apnea Neurological 0.992 0.962 – 1.02 0.599 4428 44318 all phecode
327.4 Insomnia Neurological 0.931 0.793 – 1.09 0.378 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 0.877 0.738 – 1.04 0.139 136 1390 all phecode
331 Other cerebral degenerations Neurological 0.98 0.922 – 1.04 0.51 1142 11416 all phecode
331.1 Hydrocephalus Neurological 0.967 0.883 – 1.06 0.474 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 0.967 0.875 – 1.07 0.506 430 4298 all phecode
332 Parkinson's disease Neurological 0.995 0.936 – 1.06 0.866 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.06 0.99 – 1.14 0.0964 894 8954 all phecode
333.1 Essential tremor Neurological 1.14 0.988 – 1.31 0.0741 216 2157 all phecode
333.2 Myoclonus Neurological 1.06 0.859 – 1.3 0.597 96 958 all phecode
333.4 Torsion dystonia Neurological 0.996 0.878 – 1.13 0.955 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 1.03 0.981 – 1.08 0.245 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 1.15 0.953 – 1.38 0.147 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 0.982 0.861 – 1.12 0.783 245 2446 all phecode
335 Multiple sclerosis Neurological 0.999 0.945 – 1.06 0.985 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 0.881 0.776 – 1 0.0499 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 0.983 0.774 – 1.25 0.887 72 719 all phecode
338 Pain Neurological 1.01 0.942 – 1.09 0.711 768 7692 all phecode
338.1 Acute pain Neurological 1.01 0.915 – 1.12 0.821 394 3937 all phecode
338.2 Chronic pain Neurological 0.993 0.894 – 1.1 0.899 380 3817 all phecode
339 Other headache syndromes Neurological 0.996 0.973 – 1.02 0.711 7819 78241 all phecode
340 Migraine Neurological 0.994 0.956 – 1.03 0.746 2860 28602 all phecode
340.1 Migrain with aura Neurological 0.915 0.794 – 1.05 0.217 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.01 0.893 – 1.15 0.82 252 2535 all phecode
342 Hemiplegia Neurological 1.02 0.964 – 1.07 0.54 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 0.951 0.803 – 1.13 0.559 145 1450 all phecode
344 Other paralytic syndromes Neurological 1.04 0.963 – 1.13 0.298 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.999 0.971 – 1.03 0.959 5023 50270 all phecode
345.1 Epilepsy Neurological 1.02 0.948 – 1.09 0.65 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 0.991 0.899 – 1.09 0.85 439 4385 all phecode
345.12 Partial epilepsy Neurological 1.15 1.02 – 1.3 0.0221 277 2776 all phecode
345.3 Convulsions Neurological 1.02 0.98 – 1.07 0.287 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.838 0.704 – 0.997 0.0468 144 1438 all phecode
348 Other conditions of brain Neurological 1.02 0.947 – 1.1 0.613 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.11 0.978 – 1.25 0.107 268 2678 all phecode
348.4 Cerebral cysts Neurological 0.889 0.748 – 1.06 0.181 133 1350 all phecode
348.7 Coma Neurological 1.07 0.96 – 1.19 0.23 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 0.951 0.833 – 1.08 0.452 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 1 0.902 – 1.11 0.988 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.07 0.962 – 1.2 0.203 342 3414 all phecode
350 Abnormal movement Neurological 0.987 0.949 – 1.03 0.521 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 0.96 0.896 – 1.03 0.249 887 8852 all phecode
350.2 Abnormality of gait Neurological 1 0.95 – 1.05 0.99 1596 15969 all phecode
350.3 Lack of coordination Neurological 1.01 0.912 – 1.12 0.817 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.949 0.731 – 1.23 0.694 54 540 all phecode
351 Other peripheral nerve disorders Neurological 1.01 0.993 – 1.03 0.223 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 1.03 0.975 – 1.09 0.289 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1 0.913 – 1.11 0.925 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.05 0.984 – 1.13 0.135 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 1.02 0.959 – 1.08 0.548 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 1.04 0.862 – 1.26 0.675 114 1138 all phecode
353.2 Nerve root lesions Neurological 1.04 0.796 – 1.37 0.752 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.838 0.707 – 0.994 0.0429 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 0.985 0.932 – 1.04 0.587 1361 13648 all phecode
358 Myoneural disorders Neurological 0.842 0.731 – 0.968 0.016 211 2109 all phecode
358.1 Myasthenia gravis Neurological 0.835 0.722 – 0.967 0.0162 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.949 0.86 – 1.05 0.291 465 4646 all phecode
359.1 Muscular dystrophies Neurological 0.884 0.73 – 1.07 0.209 122 1219 all phecode
359.2 Myopathy Neurological 0.987 0.884 – 1.1 0.818 360 3597 all phecode
360 Disorders of the globe Sense Organs 1.01 0.902 – 1.13 0.876 337 3367 all phecode
360.2 Progressive myopia Sense Organs 0.959 0.843 – 1.09 0.529 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 0.982 0.947 – 1.02 0.329 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.994 0.941 – 1.05 0.843 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 1.04 0.815 – 1.33 0.751 68 680 all phecode
362 Other retinal disorders Sense Organs 1.02 0.982 – 1.05 0.359 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.995 0.952 – 1.04 0.839 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.996 0.953 – 1.04 0.847 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.937 0.797 – 1.1 0.432 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 0.903 0.734 – 1.11 0.335 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1 0.936 – 1.08 0.895 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 1.04 0.892 – 1.21 0.635 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.17 0.946 – 1.45 0.145 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.05 0.863 – 1.27 0.644 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.93 0.798 – 1.09 0.357 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 1.03 0.815 – 1.31 0.791 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.01 0.937 – 1.1 0.726 647 6485 all phecode
364.1 Corneal opacity Sense Organs 0.99 0.8 – 1.22 0.923 90 910 all phecode
364.2 Corneal edema Sense Organs 0.983 0.781 – 1.24 0.883 79 800 all phecode
364.4 Corneal degenerations Sense Organs 1.04 0.9 – 1.2 0.59 201 2017 all phecode
364.41 Keratoconus Sense Organs 0.96 0.771 – 1.2 0.718 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 0.97 0.845 – 1.11 0.671 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 1.06 0.866 – 1.3 0.562 100 1000 all phecode
365 Glaucoma Sense Organs 0.992 0.962 – 1.02 0.614 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 1 0.941 – 1.07 0.921 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 1 0.942 – 1.07 0.902 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.933 0.862 – 1.01 0.0871 698 6996 all phecode
366 Cataract Sense Organs 0.99 0.975 – 1 0.163 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 1.04 0.825 – 1.31 0.74 69 700 all phecode
366.2 Senile cataract Sense Organs 0.991 0.968 – 1.01 0.422 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 0.94 0.772 – 1.14 0.535 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.01 0.969 – 1.05 0.633 2408 24092 all phecode
367.1 Myopia Sense Organs 1.01 0.955 – 1.07 0.681 1251 12519 all phecode
367.2 Astigmatism Sense Organs 0.948 0.817 – 1.1 0.486 190 1899 all phecode
367.8 Hypermetropia Sense Organs 0.891 0.783 – 1.01 0.0798 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 1.05 0.97 – 1.13 0.237 719 7198 all phecode
368 Visual disturbances Sense Organs 1.01 0.968 – 1.04 0.782 2962 29648 all phecode
368.1 Amblyopia Sense Organs 0.999 0.914 – 1.09 0.985 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.01 0.936 – 1.09 0.783 727 7288 all phecode
368.3 Anisometropia Sense Organs 1.13 0.964 – 1.33 0.13 154 1548 all phecode
368.4 Visual field defects Sense Organs 0.945 0.846 – 1.06 0.316 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 1.01 0.934 – 1.1 0.733 612 6115 all phecode
369 Infection of the eye Sense Organs 0.996 0.914 – 1.09 0.929 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 0.928 0.774 – 1.11 0.419 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 1.02 0.889 – 1.17 0.769 213 2128 all phecode
370 Keratitis Sense Organs 1.02 0.898 – 1.15 0.805 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 1.02 0.855 – 1.21 0.859 141 1408 all phecode
371 Inflammation of the eye Sense Organs 0.991 0.955 – 1.03 0.636 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.966 0.879 – 1.06 0.465 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 0.992 0.951 – 1.04 0.72 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 1.03 0.959 – 1.11 0.394 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 1.01 0.981 – 1.04 0.566 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 0.991 0.93 – 1.06 0.794 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 0.985 0.938 – 1.03 0.544 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 0.987 0.945 – 1.03 0.554 2204 22031 all phecode
375.2 Epiphora Sense Organs 1 0.936 – 1.07 0.95 898 8969 all phecode
376 Disorders of the orbit Sense Organs 1.03 0.82 – 1.29 0.816 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.955 0.858 – 1.06 0.398 361 3618 all phecode
377.1 Optic atrophy Sense Organs 0.945 0.716 – 1.25 0.691 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.979 0.811 – 1.18 0.823 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.04 0.985 – 1.1 0.153 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.992 0.927 – 1.06 0.829 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.07 0.926 – 1.23 0.374 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 1.24 1.1 – 1.41 0.000579 275 2755 all phecode
379 Other disorders of eye Sense Organs 1.01 0.972 – 1.04 0.767 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 1.02 0.964 – 1.08 0.498 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.968 0.922 – 1.02 0.188 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.13 0.892 – 1.42 0.316 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.02 0.92 – 1.13 0.719 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.97 0.827 – 1.14 0.706 169 1690 all phecode
380 Disorders of external ear Sense Organs 0.995 0.917 – 1.08 0.898 642 6413 all phecode
380.1 Otitis externa Sense Organs 0.926 0.845 – 1.01 0.098 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 1.03 0.924 – 1.15 0.603 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.03 0.987 – 1.08 0.163 2150 21493 all phecode
381.1 Otitis media Sense Organs 1.02 0.972 – 1.07 0.405 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.01 0.94 – 1.08 0.816 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 1.18 1.02 – 1.36 0.0283 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 0.868 0.741 – 1.02 0.0816 171 1709 all phecode
381.9 Otorrhea Sense Organs 1.07 0.949 – 1.21 0.265 281 2807 all phecode
382 Otalgia Sense Organs 1.09 0.972 – 1.23 0.135 308 3084 all phecode
383 Otosclerosis Sense Organs 0.952 0.848 – 1.07 0.411 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.01 0.95 – 1.06 0.846 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.01 0.947 – 1.07 0.791 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1 0.934 – 1.08 0.895 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 1.05 0.964 – 1.14 0.275 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.981 0.858 – 1.12 0.773 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.981 0.934 – 1.03 0.456 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 0.971 0.891 – 1.06 0.494 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 0.993 0.894 – 1.1 0.892 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 0.967 0.897 – 1.04 0.383 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.04 1.01 – 1.07 0.00993 4582 45806 all phecode
388 Other disorders of ear Sense Organs 1.06 0.918 – 1.23 0.421 202 2017 all phecode
389 Hearing loss Sense Organs 0.989 0.958 – 1.02 0.506 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.985 0.895 – 1.08 0.76 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 1 0.91 – 1.1 0.96 450 4497 all phecode
389.4 Tinnitus Sense Organs 0.992 0.906 – 1.09 0.868 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 0.995 0.966 – 1.02 0.74 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 0.992 0.955 – 1.03 0.658 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 1.01 0.952 – 1.07 0.766 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.01 0.951 – 1.08 0.679 1058 10566 all phecode
395 Heart valve disorders Circulatory System 0.994 0.963 – 1.03 0.717 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1 0.963 – 1.04 0.957 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.04 0.915 – 1.17 0.585 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 0.993 0.82 – 1.2 0.946 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.885 0.718 – 1.09 0.255 97 970 all phecode
395.6 Heart valve replaced Circulatory System 0.986 0.935 – 1.04 0.597 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 0.976 0.917 – 1.04 0.457 1048 10468 all phecode
401 Hypertension Circulatory System 1.01 1.01 – 1.02 0.00139 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 1.01 1.01 – 1.02 0.00133 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 0.955 0.911 – 1 0.0553 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 0.887 0.797 – 0.986 0.0259 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.975 0.925 – 1.03 0.337 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 1 0.847 – 1.19 0.968 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.01 0.956 – 1.06 0.76 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 1.01 1 – 1.03 0.0327 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.997 0.969 – 1.03 0.85 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 1.01 0.987 – 1.02 0.558 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 1.02 1 – 1.03 0.042 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.01 1 – 1.03 0.0544 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.04 0.958 – 1.12 0.38 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.01 0.991 – 1.02 0.38 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.985 0.929 – 1.04 0.61 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 1.01 0.959 – 1.06 0.801 1823 18228 all phecode
414.2 ASCVD Circulatory System 1.05 0.831 – 1.34 0.666 72 719 all phecode
415 Pulmonary heart disease Circulatory System 1.01 0.977 – 1.04 0.64 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.888 0.698 – 1.13 0.337 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.04 0.956 – 1.13 0.364 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.02 0.924 – 1.12 0.716 448 4475 all phecode
416 Cardiomegaly Circulatory System 1.02 0.977 – 1.06 0.409 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 1 0.989 – 1.01 0.875 28599 270106 all phecode
418.1 Precordial pain Circulatory System 0.951 0.919 – 0.984 0.00426 3551 35541 all phecode
420 Carditis Circulatory System 1.02 0.98 – 1.07 0.285 2106 21053 all phecode
420.1 Myocarditis Circulatory System 0.984 0.821 – 1.18 0.863 127 1267 all phecode
420.2 Pericarditis Circulatory System 1.04 0.985 – 1.1 0.153 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 0.989 0.861 – 1.14 0.878 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 0.963 0.796 – 1.17 0.702 113 1129 all phecode
420.3 Endocarditis Circulatory System 0.977 0.905 – 1.05 0.542 719 7194 all phecode
425 Cardiomyopathy Circulatory System 1.01 0.956 – 1.07 0.677 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.999 0.943 – 1.06 0.985 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.07 0.899 – 1.27 0.461 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.06 0.903 – 1.24 0.486 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 1.29 0.995 – 1.67 0.0548 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 1.02 0.997 – 1.05 0.0846 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.02 0.974 – 1.06 0.432 2114 21162 all phecode
426.21 First degree AV block Circulatory System 1.07 1 – 1.14 0.0466 986 9867 all phecode
426.23 Second degree AV block Circulatory System 0.918 0.833 – 1.01 0.0877 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 0.947 0.87 – 1.03 0.205 587 5868 all phecode
426.25 Other heart block Circulatory System 1.16 0.974 – 1.39 0.0943 131 1318 all phecode
426.3 Bundle branch block Circulatory System 1.02 0.984 – 1.06 0.274 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 0.993 0.941 – 1.05 0.781 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 1.05 0.999 – 1.1 0.0553 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.08 0.944 – 1.23 0.265 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 0.759 0.588 – 0.981 0.0349 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.02 0.983 – 1.07 0.252 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.04 0.994 – 1.08 0.0902 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 1.01 0.999 – 1.03 0.0708 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1 0.966 – 1.04 0.94 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.983 0.942 – 1.02 0.415 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.06 0.994 – 1.14 0.0766 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.01 0.998 – 1.03 0.0912 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.02 0.981 – 1.05 0.371 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.946 0.891 – 1 0.0712 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.06 0.947 – 1.18 0.326 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 0.927 0.868 – 0.99 0.0246 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.01 0.94 – 1.07 0.882 952 9541 all phecode
427.6 Premature beats Circulatory System 1.02 0.932 – 1.11 0.679 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 0.964 0.798 – 1.17 0.707 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 1.03 0.984 – 1.07 0.211 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.958 0.866 – 1.06 0.404 402 4029 all phecode
427.9 Palpitations Circulatory System 1.01 0.98 – 1.05 0.457 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.03 1 – 1.06 0.0285 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.05 1.01 – 1.1 0.0236 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 1.02 0.99 – 1.05 0.196 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.06 0.984 – 1.15 0.125 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 0.955 0.741 – 1.23 0.72 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.1 1.01 – 1.21 0.0333 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 0.913 0.789 – 1.06 0.222 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 0.99 0.944 – 1.04 0.677 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.01 0.943 – 1.09 0.747 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 0.94 0.873 – 1.01 0.0961 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 1.06 0.931 – 1.2 0.396 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 1.01 0.984 – 1.03 0.631 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.949 0.894 – 1.01 0.0899 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.01 0.88 – 1.16 0.891 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.995 0.964 – 1.03 0.775 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.975 0.927 – 1.03 0.322 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 1.02 0.985 – 1.06 0.234 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.04 0.998 – 1.09 0.0603 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 0.957 0.864 – 1.06 0.4 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1 0.947 – 1.06 0.927 1279 12783 all phecode
440 Atherosclerosis Circulatory System 0.993 0.94 – 1.05 0.796 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.03 0.853 – 1.24 0.765 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1 0.932 – 1.08 0.97 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.03 0.915 – 1.16 0.621 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.08 0.991 – 1.17 0.0794 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.07 0.943 – 1.21 0.305 283 2827 all phecode
442 Other aneurysm Circulatory System 1.01 0.961 – 1.06 0.743 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 1.01 0.953 – 1.06 0.84 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.02 0.95 – 1.09 0.641 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 0.952 0.784 – 1.16 0.617 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.967 0.828 – 1.13 0.676 169 1696 all phecode
442.4 Arterial dissection Circulatory System 0.983 0.74 – 1.31 0.907 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.04 0.903 – 1.21 0.558 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 0.998 0.966 – 1.03 0.889 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 0.997 0.939 – 1.06 0.926 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.955 0.86 – 1.06 0.393 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1 0.97 – 1.04 0.872 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1 0.961 – 1.04 0.996 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 0.931 0.871 – 0.995 0.0344 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.915 0.84 – 0.997 0.0422 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.05 0.975 – 1.12 0.204 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 1.01 0.868 – 1.17 0.922 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 1.04 0.935 – 1.15 0.496 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 1.1 0.962 – 1.25 0.165 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 0.973 0.92 – 1.03 0.339 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 0.951 0.887 – 1.02 0.151 868 8712 all phecode
448 Disease of capillaries Circulatory System 1.15 0.97 – 1.36 0.107 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.983 0.91 – 1.06 0.655 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.02 0.987 – 1.05 0.242 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.03 0.994 – 1.06 0.102 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.957 0.877 – 1.04 0.316 564 5645 all phecode
454 Varicose veins Circulatory System 1 0.984 – 1.02 0.763 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1 0.981 – 1.02 0.991 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.982 0.904 – 1.07 0.666 624 6325 all phecode
455 Hemorrhoids Circulatory System 1 0.987 – 1.01 0.949 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.05 0.905 – 1.23 0.502 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.962 0.778 – 1.19 0.718 97 967 all phecode
458 Hypotension Circulatory System 1.01 0.986 – 1.04 0.335 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 0.956 0.903 – 1.01 0.12 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.06 0.924 – 1.21 0.417 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 1.01 0.979 – 1.05 0.442 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 0.999 0.983 – 1.01 0.866 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 1.08 0.914 – 1.27 0.377 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 0.999 0.983 – 1.02 0.901 16103 159422 all phecode
464 Acute sinusitis Respiratory 1.04 0.894 – 1.2 0.644 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.02 0.976 – 1.06 0.386 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 1.02 0.953 – 1.1 0.531 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.982 0.838 – 1.15 0.821 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.982 0.953 – 1.01 0.246 4654 46553 all phecode
471 Nasal polyps Respiratory 1.03 0.997 – 1.07 0.0747 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.03 0.963 – 1.1 0.405 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1.03 0.988 – 1.07 0.171 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 1.15 0.943 – 1.4 0.168 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.03 0.912 – 1.17 0.605 264 2647 all phecode
473.4 Voice disturbance Respiratory 1.03 0.972 – 1.1 0.287 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 1.02 0.967 – 1.07 0.534 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 0.962 0.882 – 1.05 0.386 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.08 1.01 – 1.14 0.0204 1122 11199 all phecode
475 Chronic sinusitis Respiratory 1.02 0.98 – 1.06 0.333 2589 25882 all phecode
476 Allergic rhinitis Respiratory 1.05 0.983 – 1.12 0.15 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.06 1.02 – 1.11 0.00585 2447 24452 all phecode
478 Throat pain Respiratory 1.01 0.912 – 1.12 0.821 377 3789 all phecode
479 Other upper respiratory disease Respiratory 0.993 0.962 – 1.03 0.687 4074 40737 all phecode
480 Pneumonia Respiratory 1 0.985 – 1.03 0.629 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 1.01 0.985 – 1.04 0.418 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.01 0.987 – 1.04 0.321 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 0.961 0.772 – 1.2 0.719 93 929 all phecode
480.2 Viral pneumonia Respiratory 1.06 0.845 – 1.34 0.599 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.914 0.745 – 1.12 0.384 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.911 0.847 – 0.979 0.0117 794 7951 all phecode
481 Influenza Respiratory 1 0.893 – 1.12 0.973 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.05 0.903 – 1.22 0.537 193 1930 all phecode
495 Asthma Respiratory 1.01 0.992 – 1.02 0.443 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 0.976 0.858 – 1.11 0.714 250 2510 all phecode
496 Chronic airway obstruction Respiratory 0.983 0.964 – 1 0.103 10424 101546 all phecode
496.1 Emphysema Respiratory 1.03 0.983 – 1.08 0.206 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 0.981 0.944 – 1.02 0.314 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 0.982 0.944 – 1.02 0.372 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 1.01 0.966 – 1.06 0.589 1885 18859 all phecode
497 Bronchitis Respiratory 1.03 0.954 – 1.12 0.414 626 6267 all phecode
500 Lung disease due to external agents Respiratory 0.908 0.82 – 1.01 0.0632 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.85 0.673 – 1.07 0.17 79 784 all phecode
500.2 Pneumoconiosis Respiratory 0.859 0.752 – 0.981 0.0247 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 0.986 0.912 – 1.07 0.733 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.948 0.886 – 1.02 0.127 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 0.96 0.877 – 1.05 0.377 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.926 0.828 – 1.04 0.18 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 0.989 0.768 – 1.28 0.935 61 610 all phecode
506 Empyema and pneumothorax Respiratory 0.969 0.911 – 1.03 0.313 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 1 0.976 – 1.03 0.937 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.02 0.973 – 1.07 0.424 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.989 0.95 – 1.03 0.589 2599 26031 all phecode
509.1 Respiratory failure Respiratory 0.972 0.929 – 1.02 0.212 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 0.975 0.929 – 1.02 0.298 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 0.996 0.835 – 1.19 0.964 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.04 0.939 – 1.16 0.436 386 3863 all phecode
510 Other diseases of lung Respiratory 1.02 0.948 – 1.1 0.594 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 0.998 0.977 – 1.02 0.867 9031 90349 all phecode
512.1 Wheezing Respiratory 0.945 0.824 – 1.08 0.423 220 2196 all phecode
512.2 Painful respiration Respiratory 0.958 0.828 – 1.11 0.56 207 2075 all phecode
512.7 Shortness of breath Respiratory 0.993 0.966 – 1.02 0.6 5842 58498 all phecode
512.8 Cough Respiratory 0.977 0.94 – 1.02 0.237 2866 28642 all phecode
512.9 Other dyspnea Respiratory 1.07 0.995 – 1.14 0.0685 914 9124 all phecode
513 Respiratory abnormalities Respiratory 0.964 0.887 – 1.05 0.384 611 6112 all phecode
513.3 Hypoventilation Respiratory 1.23 0.978 – 1.54 0.0771 83 830 all phecode
513.4 Hyperventilation Respiratory 0.97 0.858 – 1.1 0.622 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 0.964 0.818 – 1.14 0.661 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 1.02 0.977 – 1.06 0.397 2465 24673 all phecode
516 Abnormal sputum Respiratory 0.999 0.956 – 1.04 0.964 2132 21335 all phecode
516.1 Hemoptysis Respiratory 1.02 0.971 – 1.06 0.493 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.01 0.991 – 1.03 0.257 9366 93681 all phecode
519.2 Respiratory complications Respiratory 1.07 0.952 – 1.2 0.265 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.01 0.985 – 1.03 0.539 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.09 0.966 – 1.22 0.168 303 3049 all phecode
520 Disorders of tooth development Digestive 0.993 0.949 – 1.04 0.763 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.991 0.759 – 1.29 0.945 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 1 0.959 – 1.04 0.98 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 0.989 0.953 – 1.03 0.569 3016 30245 all phecode
521.1 Dental caries Digestive 0.992 0.956 – 1.03 0.671 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 0.969 0.923 – 1.02 0.205 1774 17750 all phecode
522.5 Periapical abscess Digestive 0.989 0.931 – 1.05 0.707 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 1.02 0.969 – 1.07 0.474 1681 16812 all phecode
523.1 Gingivitis Digestive 1.12 0.923 – 1.37 0.245 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.03 0.97 – 1.09 0.33 1165 11650 all phecode
523.31 Acute periodontitis Digestive 1.04 0.963 – 1.13 0.299 666 6667 all phecode
523.32 Chronic periodontitis Digestive 1 0.919 – 1.09 0.958 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.03 0.921 – 1.16 0.587 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.03 0.92 – 1.16 0.57 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.03 0.986 – 1.07 0.207 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.916 0.724 – 1.16 0.467 72 720 all phecode
526 Diseases of the jaws Digestive 1.04 0.97 – 1.11 0.282 928 9279 all phecode
526.1 Cysts of the jaws Digestive 1.01 0.9 – 1.12 0.918 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.917 0.713 – 1.18 0.501 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.07 0.941 – 1.23 0.286 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.08 0.941 – 1.23 0.281 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 1.14 0.937 – 1.38 0.196 110 1098 all phecode
526.9 Jaw disease NOS Digestive 1.03 0.897 – 1.17 0.708 233 2329 all phecode
527 Diseases of the salivary glands Digestive 0.999 0.925 – 1.08 0.986 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.03 0.82 – 1.28 0.825 84 838 all phecode
527.2 Sialoadenitis Digestive 1.02 0.915 – 1.13 0.765 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 0.988 0.769 – 1.27 0.927 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 0.995 0.825 – 1.2 0.957 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1 0.968 – 1.03 0.995 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 1.1 0.999 – 1.21 0.0518 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.1 0.991 – 1.22 0.0737 389 3884 all phecode
528.12 Oral aphthae Digestive 1.15 0.919 – 1.44 0.221 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.05 0.899 – 1.22 0.547 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 0.947 0.791 – 1.13 0.556 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 0.943 0.763 – 1.17 0.587 94 940 all phecode
528.5 Diseases of lips Digestive 0.952 0.88 – 1.03 0.218 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 0.951 0.848 – 1.07 0.397 308 3079 all phecode
528.7 Sialolithiasis Digestive 0.989 0.883 – 1.11 0.849 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 0.946 0.892 – 1 0.0613 1232 12312 all phecode
529.1 Glossitis Digestive 0.974 0.867 – 1.09 0.657 299 2986 all phecode
530 Diseases of esophagus Digestive 0.996 0.985 – 1.01 0.474 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.996 0.985 – 1.01 0.524 31253 272429 all phecode
530.11 GERD Digestive 0.997 0.984 – 1.01 0.682 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 0.982 0.954 – 1.01 0.216 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 1 0.983 – 1.02 0.801 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.998 0.95 – 1.05 0.944 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.04 0.993 – 1.09 0.0974 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 0.972 0.897 – 1.05 0.498 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.3 1.09 – 1.54 0.00322 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.935 0.834 – 1.05 0.243 341 3416 all phecode
530.9 Heartburn Digestive 1 0.961 – 1.05 0.843 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.984 0.96 – 1.01 0.19 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.05 0.966 – 1.14 0.262 637 6374 all phecode
531.2 Gastric ulcer Digestive 0.989 0.958 – 1.02 0.508 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 0.974 0.938 – 1.01 0.175 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 0.871 0.79 – 0.961 0.00592 427 4268 all phecode
532 Dysphagia Digestive 1.02 0.995 – 1.05 0.111 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 0.995 0.983 – 1.01 0.467 28078 261548 all phecode
535.1 Acute gastritis Digestive 1 0.943 – 1.06 0.975 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 1.02 0.919 – 1.14 0.689 370 3687 all phecode
535.6 Duodenitis Digestive 0.977 0.954 – 1 0.0516 7592 75928 all phecode
535.8 Other specified gastritis Digestive 0.995 0.972 – 1.02 0.662 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.862 0.715 – 1.04 0.119 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.992 0.874 – 1.13 0.903 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 0.974 0.94 – 1.01 0.139 3391 33907 all phecode
540 Appendiceal conditions Digestive 0.993 0.957 – 1.03 0.704 3088 30890 all phecode
540.1 Appendicitis Digestive 0.998 0.961 – 1.04 0.928 2895 28963 all phecode
540.11 Acute appendicitis Digestive 0.996 0.956 – 1.04 0.837 2601 26019 all phecode
550 Abdominal hernia Digestive 1.01 1 – 1.02 0.0267 45429 282640 all phecode
550.1 Inguinal hernia Digestive 1.03 1.01 – 1.04 0.00183 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 1 0.99 – 1.02 0.65 26494 238953 all phecode
550.3 Femoral hernia Digestive 0.973 0.899 – 1.05 0.503 651 6504 all phecode
550.4 Umbilical hernia Digestive 1.01 0.976 – 1.04 0.577 3705 37072 all phecode
550.5 Ventral hernia Digestive 1.01 0.974 – 1.05 0.614 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.01 0.974 – 1.04 0.747 4444 44442 all phecode
555.1 Regional enteritis Digestive 0.958 0.912 – 1.01 0.0884 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 1.02 0.979 – 1.05 0.408 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.07 0.976 – 1.17 0.149 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 1.03 0.969 – 1.1 0.319 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 0.979 0.905 – 1.06 0.589 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.89 0.791 – 1 0.0522 299 2987 all phecode
557.1 Celiac disease Digestive 0.81 0.772 – 0.85 9.78e-18 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 1.01 0.994 – 1.03 0.203 15492 155105 all phecode
559 Ileostomy status Digestive 0.991 0.942 – 1.04 0.72 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 0.983 0.951 – 1.02 0.294 3936 39337 all phecode
560.1 Paralytic ileus Digestive 1.04 0.949 – 1.13 0.412 523 5231 all phecode
560.2 Impaction of intestine Digestive 0.883 0.78 – 0.999 0.049 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.969 0.902 – 1.04 0.387 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 0.984 0.949 – 1.02 0.37 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 0.994 0.978 – 1.01 0.469 15772 157686 all phecode
561.1 Diarrhea Digestive 0.95 0.862 – 1.05 0.294 466 4653 all phecode
561.2 Flatulence Digestive 1.01 0.961 – 1.06 0.685 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 1.01 0.999 – 1.02 0.0808 26714 211692 all phecode
562.1 Diverticulosis Digestive 1.01 0.999 – 1.02 0.0772 26672 211642 all phecode
563 Constipation Digestive 1.01 0.993 – 1.03 0.184 10314 103140 all phecode
564 Functional digestive disorders Digestive 0.997 0.983 – 1.01 0.662 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 0.987 0.96 – 1.02 0.374 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.04 0.988 – 1.09 0.138 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 0.997 0.98 – 1.01 0.684 15186 151648 all phecode
565 Anal and rectal conditions Digestive 1.02 1 – 1.04 0.0179 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 1.02 0.995 – 1.04 0.126 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.02 0.955 – 1.09 0.522 929 9293 all phecode
568 Other disorders of peritoneum Digestive 0.998 0.962 – 1.03 0.904 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.999 0.963 – 1.04 0.972 3101 30987 all phecode
569 Other disorders of intestine Digestive 0.994 0.963 – 1.03 0.712 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.12 0.944 – 1.33 0.192 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 1.04 0.944 – 1.14 0.448 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 0.995 0.958 – 1.03 0.784 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 0.989 0.941 – 1.04 0.679 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.915 0.759 – 1.1 0.35 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 0.984 0.866 – 1.12 0.805 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.977 0.915 – 1.04 0.494 976 9804 all phecode
571.81 Portal hypertension Digestive 0.961 0.879 – 1.05 0.371 528 5285 all phecode
572 Ascites (non malignant) Digestive 0.98 0.93 – 1.03 0.438 1544 15454 all phecode
573 Other disorders of liver Digestive 1.03 0.977 – 1.09 0.273 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 0.881 0.719 – 1.08 0.223 96 960 all phecode
573.3 Hepatomegaly Digestive 1.02 0.903 – 1.14 0.797 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 0.972 0.908 – 1.04 0.415 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 0.967 0.934 – 1 0.0647 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.25 1.08 – 1.44 0.00223 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 1 0.987 – 1.02 0.667 15607 156123 all phecode
574.1 Cholelithiasis Digestive 0.999 0.981 – 1.02 0.908 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.02 0.969 – 1.08 0.424 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.02 0.992 – 1.05 0.169 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 1.04 0.999 – 1.08 0.0569 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.998 0.959 – 1.04 0.914 2748 27523 all phecode
575 Other biliary tract disease Digestive 1 0.97 – 1.04 0.857 3867 38724 all phecode
575.1 Cholangitis Digestive 0.937 0.855 – 1.03 0.167 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 0.976 0.906 – 1.05 0.522 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 1.07 0.967 – 1.17 0.197 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 0.994 0.941 – 1.05 0.819 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 1 0.939 – 1.07 0.975 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.05 0.938 – 1.17 0.415 348 3488 all phecode
577 Diseases of pancreas Digestive 0.973 0.935 – 1.01 0.175 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 0.979 0.935 – 1.03 0.376 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 0.981 0.897 – 1.07 0.674 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.925 0.832 – 1.03 0.15 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.998 – 1.03 0.0961 20626 206278 all phecode
578.1 Hematemesis Digestive 1.02 0.972 – 1.07 0.452 1958 19564 all phecode
578.2 Blood in stool Digestive 0.97 0.931 – 1.01 0.134 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.02 1 – 1.04 0.0559 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.01 0.981 – 1.04 0.53 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.03 0.981 – 1.09 0.212 1548 15498 all phecode
579.2 Splenomegaly Digestive 1.03 0.932 – 1.14 0.563 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.04 0.986 – 1.09 0.156 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.977 0.927 – 1.03 0.384 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 0.998 0.936 – 1.06 0.943 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.809 0.634 – 1.03 0.0868 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.1 0.93 – 1.31 0.261 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.999 0.932 – 1.07 0.973 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.933 0.849 – 1.02 0.146 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.974 0.855 – 1.11 0.688 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.982 0.865 – 1.12 0.783 253 2529 all phecode
585 Renal failure Genitourinary 1.02 0.999 – 1.05 0.0587 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 1.03 0.998 – 1.06 0.069 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 1.05 0.995 – 1.11 0.0735 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.996 0.957 – 1.04 0.829 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 0.955 0.872 – 1.05 0.325 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 0.994 0.959 – 1.03 0.736 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.914 0.793 – 1.05 0.21 208 2089 all phecode
586.11 Small kidney Genitourinary 0.9 0.773 – 1.05 0.175 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.01 0.954 – 1.07 0.718 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.929 0.745 – 1.16 0.514 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.95 0.888 – 1.02 0.145 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 0.922 0.828 – 1.03 0.137 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 0.848 0.687 – 1.05 0.123 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.08 0.892 – 1.3 0.44 116 1158 all phecode
590 Pyelonephritis Genitourinary 0.976 0.923 – 1.03 0.402 1328 13285 all phecode
591 Urinary tract infection Genitourinary 1.03 1.01 – 1.04 0.00788 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 1.04 0.997 – 1.08 0.0701 2966 29661 all phecode
592.1 Cystitis Genitourinary 1.03 0.996 – 1.08 0.0828 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 1.07 0.902 – 1.28 0.426 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 1.06 0.988 – 1.13 0.104 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.997 0.875 – 1.14 0.966 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.05 0.893 – 1.24 0.549 165 1662 all phecode
593 Hematuria Genitourinary 1.04 1.02 – 1.06 1.71e-06 16068 160204 all phecode
594 Urinary calculus Genitourinary 1.02 0.99 – 1.04 0.233 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 1.02 0.985 – 1.06 0.256 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.12 1.04 – 1.21 0.00253 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 1.03 0.983 – 1.07 0.241 2401 24024 all phecode
594.8 Renal colic Genitourinary 0.969 0.926 – 1.01 0.183 2050 20500 all phecode
595 Hydronephrosis Genitourinary 1.03 0.979 – 1.07 0.279 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 1.06 1.04 – 1.08 5.31e-08 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 1.11 1.06 – 1.17 5.35e-06 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 1.04 0.991 – 1.1 0.104 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.08 1.04 – 1.11 8.78e-06 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.08 1.04 – 1.12 1.59e-05 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 0.858 0.679 – 1.08 0.199 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.08 1.05 – 1.12 4.51e-06 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.08 0.961 – 1.21 0.194 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.06 1.04 – 1.08 9.02e-14 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 1.08 0.922 – 1.27 0.334 166 1670 all phecode
599.2 Retention of urine Genitourinary 1.07 1.04 – 1.1 9.55e-08 6718 67168 all phecode
599.3 Dysuria Genitourinary 1.01 0.954 – 1.07 0.687 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 1.06 1.03 – 1.08 1.55e-06 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.04 1.01 – 1.08 0.00916 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 1.24 1.02 – 1.51 0.0322 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.08 0.844 – 1.38 0.543 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 1.05 1.01 – 1.11 0.0264 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 1.12 1.1 – 1.14 1.18e-28 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 1.14 1.09 – 1.19 3.21e-08 2081 20818 all phecode
601.1 Prostatitis Genitourinary 1.16 1.1 – 1.22 4.86e-08 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 1.18 1.03 – 1.34 0.0169 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 1.17 1.09 – 1.25 9.29e-06 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.07 0.822 – 1.39 0.617 59 588 all phecode
601.4 Balanoposthitis Genitourinary 1.06 0.939 – 1.2 0.338 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.07 0.957 – 1.2 0.225 303 3019 all phecode
602 Other disorders of prostate Genitourinary 1.27 1.2 – 1.34 2.02e-16 1341 13408 all phecode
603 Other disorders of testis Genitourinary 1.01 0.967 – 1.06 0.657 2150 21512 all phecode
603.1 Hydrocele Genitourinary 1.02 0.966 – 1.08 0.457 1339 13402 all phecode
604 Disorders of penis Genitourinary 0.999 0.964 – 1.04 0.96 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.996 0.957 – 1.04 0.835 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.22 1.08 – 1.38 0.00122 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 0.977 0.94 – 1.02 0.231 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.22 1.06 – 1.4 0.00657 214 2138 all phecode
609.1 Infertility, male Genitourinary 0.912 0.707 – 1.18 0.479 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 1.33 1.14 – 1.56 0.000438 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 1.01 0.965 – 1.05 0.764 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 1 0.938 – 1.07 0.906 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 1 0.889 – 1.13 0.969 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 1.01 0.894 – 1.14 0.904 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.994 0.941 – 1.05 0.845 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.07 0.99 – 1.16 0.087 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.969 0.919 – 1.02 0.234 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 0.893 0.679 – 1.17 0.414 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 0.969 0.919 – 1.02 0.246 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.993 0.928 – 1.06 0.844 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1 0.934 – 1.07 0.965 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 1.05 0.826 – 1.32 0.713 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 1.02 0.972 – 1.08 0.399 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 0.998 0.924 – 1.08 0.952 720 7210 all phecode
613.5 Mastodynia Genitourinary 0.929 0.732 – 1.18 0.544 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 1.03 0.954 – 1.11 0.446 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 1.08 0.961 – 1.2 0.205 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 0.974 0.845 – 1.12 0.718 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1 0.975 – 1.03 0.908 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.01 0.975 – 1.06 0.474 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.977 0.91 – 1.05 0.524 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.847 0.653 – 1.1 0.21 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.927 0.838 – 1.03 0.141 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.01 0.905 – 1.12 0.877 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1 0.888 – 1.13 0.998 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.989 0.95 – 1.03 0.599 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.985 0.931 – 1.04 0.589 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.939 0.85 – 1.04 0.215 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.02 0.948 – 1.1 0.564 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.946 0.835 – 1.07 0.381 274 2737 all phecode
615 Endometriosis Genitourinary 1 0.969 – 1.03 0.94 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 0.934 0.83 – 1.05 0.252 304 3037 all phecode
618 Genital prolapse Genitourinary 1.02 1 – 1.04 0.0248 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1.01 0.982 – 1.03 0.615 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.04 1.01 – 1.07 0.00892 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.1 1.01 – 1.21 0.035 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.02 0.944 – 1.1 0.604 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 1.01 0.99 – 1.03 0.281 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.07 0.989 – 1.15 0.0917 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1 0.968 – 1.04 0.879 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1 0.966 – 1.04 0.824 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.03 0.983 – 1.08 0.205 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.04 0.985 – 1.1 0.15 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 1.22 0.96 – 1.56 0.104 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 1.04 0.976 – 1.1 0.24 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 1.03 1.01 – 1.05 0.00198 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 1.05 1.02 – 1.07 6.14e-05 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.988 0.954 – 1.02 0.517 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 0.972 0.917 – 1.03 0.342 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 0.946 0.88 – 1.02 0.139 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.929 0.813 – 1.06 0.285 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.988 0.897 – 1.09 0.813 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 1.01 0.982 – 1.04 0.547 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.976 0.939 – 1.01 0.206 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 0.962 0.906 – 1.02 0.199 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1 0.984 – 1.02 0.928 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1 0.985 – 1.02 0.735 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.862 0.706 – 1.05 0.147 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.01 0.988 – 1.03 0.425 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 1.02 0.976 – 1.07 0.341 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.99 0.957 – 1.02 0.556 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 0.98 0.933 – 1.03 0.409 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 1.03 0.872 – 1.21 0.761 159 1587 all phecode
626.8 Infertility, female Genitourinary 0.989 0.936 – 1.05 0.711 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1 0.984 – 1.02 0.714 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 1 0.981 – 1.02 0.849 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 0.974 0.839 – 1.13 0.734 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.983 0.924 – 1.05 0.584 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 1.01 0.895 – 1.13 0.911 310 3097 all phecode
628 Ovarian cyst Genitourinary 1.02 0.99 – 1.05 0.193 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1 0.975 – 1.03 0.759 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.02 0.958 – 1.08 0.545 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.05 0.938 – 1.17 0.405 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.01 0.961 – 1.06 0.767 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.02 0.947 – 1.09 0.646 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1 0.948 – 1.06 0.879 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.04 0.997 – 1.09 0.069 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 1.03 0.944 – 1.12 0.537 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.01 0.951 – 1.08 0.707 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 0.957 0.747 – 1.23 0.728 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.01 0.946 – 1.07 0.836 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.973 0.867 – 1.09 0.634 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.05 0.917 – 1.21 0.466 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.963 0.819 – 1.13 0.645 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.06 1 – 1.13 0.0345 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.01 0.968 – 1.06 0.622 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.06 0.83 – 1.35 0.647 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.03 0.907 – 1.16 0.678 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.967 0.8 – 1.17 0.726 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.01 0.869 – 1.17 0.927 193 1922 all phecode
650 Normal delivery Pregnancy Complications 1.04 0.996 – 1.1 0.0698 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 1.08 0.97 – 1.21 0.153 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.995 0.946 – 1.05 0.829 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.01 0.954 – 1.07 0.775 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.02 0.808 – 1.28 0.874 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.987 0.956 – 1.02 0.437 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.02 0.844 – 1.23 0.831 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.99 0.948 – 1.03 0.659 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 1.04 0.952 – 1.14 0.376 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.999 0.97 – 1.03 0.946 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.969 0.93 – 1.01 0.136 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.03 0.875 – 1.21 0.735 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.972 0.855 – 1.1 0.659 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.878 0.675 – 1.14 0.33 63 624 all phecode
679 Complications of in utero procedures Dermatologic 0.981 0.738 – 1.3 0.894 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.01 0.989 – 1.04 0.273 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1 0.919 – 1.09 0.976 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.933 0.851 – 1.02 0.142 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.01 0.982 – 1.04 0.502 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.01 0.986 – 1.04 0.327 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.01 0.983 – 1.04 0.443 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.03 0.95 – 1.12 0.452 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.02 0.96 – 1.08 0.58 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 1 0.959 – 1.04 0.967 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 1.03 0.945 – 1.12 0.52 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 1.1 0.987 – 1.22 0.0846 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 0.971 0.89 – 1.06 0.512 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.03 0.989 – 1.08 0.145 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 0.983 0.869 – 1.11 0.787 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 0.993 0.812 – 1.21 0.942 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 0.997 0.96 – 1.04 0.889 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.997 0.97 – 1.02 0.803 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.88 0.684 – 1.13 0.32 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.99 0.75 – 1.31 0.944 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 1.15 0.953 – 1.38 0.147 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.985 0.922 – 1.05 0.641 986 9854 all phecode
694.1 Vitiligo Dermatologic 1.11 0.859 – 1.44 0.424 60 599 all phecode
694.2 Other dyschromia Dermatologic 0.946 0.879 – 1.02 0.137 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 1.13 0.941 – 1.36 0.188 117 1170 all phecode
695 Erythematous conditions Dermatologic 0.958 0.918 – 0.999 0.0446 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 0.906 0.75 – 1.1 0.31 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 1.02 0.861 – 1.22 0.79 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 0.995 0.763 – 1.3 0.971 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.05 0.833 – 1.33 0.665 73 727 all phecode
695.3 Rosacea Dermatologic 0.999 0.891 – 1.12 0.98 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 0.972 0.877 – 1.08 0.579 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.971 0.812 – 1.16 0.746 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 0.973 0.87 – 1.09 0.634 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 0.981 0.911 – 1.06 0.602 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 1 0.879 – 1.15 0.956 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 0.926 0.732 – 1.17 0.519 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 0.897 0.815 – 0.987 0.0255 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 0.964 0.923 – 1.01 0.103 2252 22509 all phecode
696.4 Psoriasis Dermatologic 0.962 0.92 – 1 0.0808 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 0.944 0.897 – 0.992 0.0235 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 0.992 0.919 – 1.07 0.839 706 7052 all phecode
697 Sarcoidosis Dermatologic 1.01 0.927 – 1.11 0.764 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 1.05 0.978 – 1.13 0.168 782 7814 all phecode
700 Corns and callosities Dermatologic 0.927 0.823 – 1.05 0.219 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.989 0.96 – 1.02 0.485 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 0.956 0.774 – 1.18 0.673 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.01 0.973 – 1.06 0.5 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 0.947 0.727 – 1.23 0.689 61 610 all phecode
701.4 Keloid scar Dermatologic 1.06 0.927 – 1.22 0.379 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 0.899 0.816 – 0.99 0.0306 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.07 0.883 – 1.31 0.477 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.02 0.99 – 1.05 0.211 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 0.995 0.955 – 1.04 0.793 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 1.04 1 – 1.08 0.035 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 0.935 0.839 – 1.04 0.22 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 1.01 0.947 – 1.08 0.739 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 1.01 0.986 – 1.04 0.329 5267 52727 all phecode
704.1 Alopecia Dermatologic 1.01 0.841 – 1.22 0.885 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.826 0.65 – 1.05 0.118 76 759 all phecode
705 Disorders of sweat glands Dermatologic 0.991 0.864 – 1.14 0.899 228 2287 all phecode
705.3 Hidradenitis Dermatologic 1.02 0.877 – 1.18 0.804 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 0.983 0.903 – 1.07 0.688 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 1.02 0.995 – 1.04 0.121 8317 83195 all phecode
706.1 Acne Dermatologic 1.05 0.836 – 1.32 0.671 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 1.02 1 – 1.05 0.0443 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 0.979 0.935 – 1.03 0.37 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 0.978 0.914 – 1.05 0.522 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.98 0.946 – 1.01 0.254 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 0.975 0.89 – 1.07 0.591 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 1.03 0.883 – 1.2 0.723 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.914 0.713 – 1.17 0.479 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.991 0.952 – 1.03 0.648 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.98 0.901 – 1.06 0.627 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 0.976 0.895 – 1.07 0.591 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.919 0.795 – 1.06 0.251 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1 0.902 – 1.11 1 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 1 0.909 – 1.11 0.934 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 0.988 0.883 – 1.11 0.832 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 0.904 0.723 – 1.13 0.377 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.01 0.856 – 1.2 0.865 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.11 0.862 – 1.44 0.409 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.06 1.02 – 1.09 0.000351 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.06 1.03 – 1.09 0.000187 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.03 0.979 – 1.08 0.249 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.1 0.907 – 1.32 0.345 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1 0.921 – 1.09 0.975 618 6177 all phecode
716 Other arthropathies Musculoskeletal 0.997 0.986 – 1.01 0.553 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.995 0.961 – 1.03 0.785 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.99 0.974 – 1.01 0.23 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 0.996 0.985 – 1.01 0.507 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.05 0.987 – 1.11 0.128 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 1.01 0.973 – 1.04 0.701 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 0.988 0.965 – 1.01 0.316 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.983 0.955 – 1.01 0.236 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.971 0.838 – 1.12 0.692 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 0.989 0.887 – 1.1 0.835 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 0.986 0.965 – 1.01 0.208 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.993 0.907 – 1.09 0.873 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.983 0.946 – 1.02 0.394 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.27 0.994 – 1.63 0.056 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.01 0.976 – 1.04 0.65 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 1 0.914 – 1.1 0.978 517 5173 all phecode
723.1 Torticollis Musculoskeletal 1.08 0.881 – 1.31 0.477 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 0.998 0.954 – 1.04 0.936 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 0.987 0.89 – 1.09 0.806 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 0.991 0.894 – 1.1 0.856 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 0.926 0.711 – 1.21 0.569 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 0.999 0.949 – 1.05 0.965 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.993 0.976 – 1.01 0.421 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 0.99 0.97 – 1.01 0.366 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 0.993 0.89 – 1.11 0.905 334 3336 all phecode
726.3 Bursitis Musculoskeletal 0.997 0.929 – 1.07 0.924 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.999 0.975 – 1.02 0.925 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.997 0.959 – 1.04 0.872 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 0.923 0.76 – 1.12 0.419 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1 0.968 – 1.04 0.829 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 0.949 0.873 – 1.03 0.218 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.1 0.989 – 1.22 0.0798 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.941 0.792 – 1.12 0.485 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.989 0.956 – 1.02 0.526 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.01 0.913 – 1.12 0.836 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 0.995 0.962 – 1.03 0.748 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.992 0.958 – 1.03 0.651 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 0.984 0.958 – 1.01 0.226 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.982 0.921 – 1.05 0.579 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 0.742 0.602 – 0.915 0.00517 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.951 0.839 – 1.08 0.433 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.939 0.826 – 1.07 0.339 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 1.12 1.02 – 1.23 0.0188 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.13 0.98 – 1.3 0.0915 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.22 0.923 – 1.61 0.162 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.977 0.931 – 1.03 0.351 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 0.878 0.781 – 0.987 0.0287 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.948 0.869 – 1.03 0.225 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 1.02 0.856 – 1.22 0.797 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.01 0.95 – 1.07 0.815 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 1.11 0.924 – 1.32 0.27 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 1.01 0.988 – 1.03 0.416 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 0.916 0.786 – 1.07 0.256 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 0.988 0.96 – 1.02 0.418 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.999 0.954 – 1.05 0.981 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 0.957 0.909 – 1.01 0.102 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.02 0.99 – 1.04 0.231 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 1.03 0.98 – 1.09 0.234 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.04 0.915 – 1.18 0.549 248 2476 all phecode
737 Curvature of spine Musculoskeletal 1.05 0.984 – 1.11 0.148 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.05 0.987 – 1.12 0.123 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.02 0.969 – 1.06 0.53 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.02 0.972 – 1.08 0.379 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 1.03 0.943 – 1.13 0.471 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 0.997 0.985 – 1.01 0.68 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.989 0.974 – 1 0.179 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.986 0.964 – 1.01 0.186 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.968 0.866 – 1.08 0.571 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.94 0.863 – 1.02 0.16 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1 0.985 – 1.02 0.677 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.978 0.945 – 1.01 0.21 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 0.965 0.79 – 1.18 0.725 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 0.971 0.893 – 1.06 0.485 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 1.02 0.867 – 1.2 0.817 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 0.971 0.919 – 1.03 0.295 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 0.897 0.738 – 1.09 0.271 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 1.02 0.769 – 1.36 0.877 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.03 0.988 – 1.07 0.183 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 1.04 0.93 – 1.16 0.494 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.961 0.781 – 1.18 0.704 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.06 0.971 – 1.17 0.184 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 1.02 0.978 – 1.07 0.311 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.02 0.993 – 1.04 0.164 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 1.02 0.999 – 1.05 0.0602 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 1.01 0.979 – 1.03 0.658 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1.26 1.15 – 1.37 2.43e-07 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 0.975 0.889 – 1.07 0.589 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.999 0.93 – 1.07 0.972 815 8144 all phecode
745 Pain in joint Musculoskeletal 0.98 0.958 – 1 0.0903 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.01 0.974 – 1.05 0.521 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.02 0.981 – 1.06 0.314 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1 0.922 – 1.09 0.94 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.03 0.903 – 1.17 0.659 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.03 0.986 – 1.09 0.168 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.889 0.759 – 1.04 0.144 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.977 0.741 – 1.29 0.872 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.06 0.945 – 1.2 0.311 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.972 0.899 – 1.05 0.471 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.965 0.861 – 1.08 0.542 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.03 0.888 – 1.19 0.721 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.956 0.859 – 1.06 0.409 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.03 0.903 – 1.18 0.652 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.876 0.726 – 1.06 0.167 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.03 0.975 – 1.08 0.31 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.01 0.934 – 1.09 0.801 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.05 0.951 – 1.15 0.348 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.869 0.757 – 0.997 0.0456 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.06 0.987 – 1.14 0.11 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 1.12 1.01 – 1.23 0.0297 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.978 0.874 – 1.09 0.699 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.02 0.915 – 1.15 0.675 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 0.968 0.852 – 1.1 0.617 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 1.04 0.903 – 1.19 0.598 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.16 0.918 – 1.48 0.209 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.06 0.881 – 1.27 0.541 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.12 0.887 – 1.42 0.336 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.03 0.848 – 1.26 0.752 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1 0.907 – 1.1 0.983 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.04 0.903 – 1.2 0.592 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.914 0.778 – 1.07 0.272 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.964 0.793 – 1.17 0.711 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.08 0.995 – 1.18 0.0649 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.15 0.915 – 1.44 0.231 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.11 1.01 – 1.22 0.0361 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.03 0.871 – 1.21 0.765 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.02 0.796 – 1.32 0.852 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.04 0.908 – 1.2 0.541 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.15 0.929 – 1.42 0.203 96 959 all phecode
760 Back pain Symptoms 0.997 0.978 – 1.02 0.757 11126 111353 all phecode
761 Cervicalgia Symptoms 0.974 0.928 – 1.02 0.288 1791 17901 all phecode
764 Sciatica Symptoms 0.979 0.938 – 1.02 0.314 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.01 0.952 – 1.07 0.736 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 0.975 0.898 – 1.06 0.546 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.02 0.949 – 1.09 0.628 870 8687 all phecode
771.1 Swelling of limb Symptoms 0.982 0.953 – 1.01 0.231 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 1.01 0.929 – 1.09 0.899 659 6581 all phecode
773 Pain in limb Symptoms 0.982 0.957 – 1.01 0.181 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 1.04 0.893 – 1.21 0.624 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.987 0.941 – 1.03 0.576 1870 18715 all phecode
782.3 Edema Symptoms 1 0.954 – 1.06 0.876 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 1.12 0.961 – 1.31 0.145 175 1748 all phecode
783 Fever of unknown origin Symptoms 1.03 0.995 – 1.06 0.0957 3911 39105 all phecode
785 Abdominal pain Symptoms 0.997 0.987 – 1.01 0.584 40080 301686 all phecode
788 Syncope and collapse Symptoms 1 0.981 – 1.02 0.811 9069 90813 all phecode
789 Nausea and vomiting Symptoms 1.01 0.989 – 1.03 0.402 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.13 0.955 – 1.33 0.156 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 0.926 0.734 – 1.17 0.518 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.14 1.11 – 1.17 1.45e-23 6357 63635 all phecode
791 Gangrene Symptoms 0.987 0.904 – 1.08 0.773 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.978 0.791 – 1.21 0.837 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.903 0.759 – 1.08 0.254 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.05 0.961 – 1.14 0.291 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.03 0.855 – 1.24 0.763 120 1198 all phecode
797 Shock Symptoms 0.973 0.83 – 1.14 0.735 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 1.04 0.864 – 1.26 0.653 102 1020 all phecode
798 Malaise and fatigue Symptoms 1.01 0.977 – 1.05 0.517 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 0.982 0.903 – 1.07 0.67 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 1.02 0.992 – 1.04 0.2 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.05 0.999 – 1.1 0.056 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.936 0.801 – 1.09 0.403 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.987 0.944 – 1.03 0.555 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 1.04 0.961 – 1.11 0.361 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.981 0.939 – 1.02 0.381 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 0.987 0.941 – 1.04 0.595 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 1.04 0.965 – 1.13 0.289 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.991 0.969 – 1.01 0.441 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.01 0.96 – 1.06 0.734 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.985 0.958 – 1.01 0.31 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.01 0.957 – 1.06 0.765 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.994 0.959 – 1.03 0.72 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.996 0.942 – 1.05 0.876 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 0.94 0.873 – 1.01 0.1 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.963 0.909 – 1.02 0.188 1300 12998 all phecode
817 Concussion Injuries & Poisonings 0.998 0.877 – 1.14 0.975 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.936 0.856 – 1.02 0.15 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.991 0.954 – 1.03 0.632 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 0.991 0.942 – 1.04 0.713 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 1 0.959 – 1.05 0.888 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 1 0.988 – 1.02 0.631 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 0.967 0.885 – 1.06 0.462 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 0.969 0.881 – 1.06 0.511 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.992 0.965 – 1.02 0.597 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.986 0.841 – 1.16 0.863 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.03 0.942 – 1.13 0.492 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.97 0.924 – 1.02 0.204 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.15 1.08 – 1.22 4.64e-06 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.991 0.955 – 1.03 0.639 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 0.967 0.933 – 1 0.068 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1.05 0.817 – 1.36 0.687 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.997 0.962 – 1.03 0.844 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.23 1.08 – 1.38 0.00111 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 1.08 0.935 – 1.25 0.292 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.986 0.949 – 1.02 0.46 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.02 0.887 – 1.17 0.802 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 1.23 0.952 – 1.58 0.115 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 0.988 0.957 – 1.02 0.468 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.979 0.75 – 1.28 0.873 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.14 0.918 – 1.43 0.232 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.19 1.02 – 1.39 0.0284 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 1.03 0.939 – 1.13 0.525 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 0.987 0.864 – 1.13 0.846 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 0.994 0.85 – 1.16 0.944 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.05 0.889 – 1.24 0.571 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.01 0.955 – 1.07 0.703 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.02 0.985 – 1.05 0.306 4260 42663 all phecode
916 Contusion Injuries & Poisonings 1.06 1 – 1.12 0.0385 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 1.04 0.897 – 1.21 0.578 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.963 0.868 – 1.07 0.483 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 1 0.883 – 1.14 0.951 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.03 0.984 – 1.08 0.216 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.05 0.917 – 1.2 0.479 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.955 0.783 – 1.16 0.647 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.02 0.932 – 1.11 0.731 550 5509 all phecode
947 Urticaria Injuries & Poisonings 0.986 0.887 – 1.1 0.791 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 0.944 0.852 – 1.04 0.266 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.958 0.868 – 1.06 0.388 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.03 0.911 – 1.17 0.626 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.925 0.844 – 1.01 0.0939 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 0.677 0.508 – 0.901 0.0076 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.964 0.757 – 1.23 0.765 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.996 0.981 – 1.01 0.595 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.995 0.978 – 1.01 0.515 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.05 0.951 – 1.16 0.33 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.01 0.939 – 1.08 0.852 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.06 0.95 – 1.18 0.313 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.03 0.928 – 1.15 0.543 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.03 0.897 – 1.18 0.698 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.03 0.914 – 1.16 0.615 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.02 0.902 – 1.15 0.749 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.02 0.995 – 1.05 0.108 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.966 0.909 – 1.03 0.268 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.02 0.93 – 1.12 0.651 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.993 0.897 – 1.1 0.889 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.1 1 – 1.2 0.0405 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.995 0.914 – 1.08 0.904 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.04 0.994 – 1.09 0.0849 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.06 0.915 – 1.23 0.435 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.981 0.861 – 1.12 0.767 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.808 0.641 – 1.02 0.0711 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 0.951 0.777 – 1.16 0.622 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.16 0.951 – 1.42 0.142 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.15 0.906 – 1.47 0.245 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.935 0.721 – 1.21 0.612 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.953 0.834 – 1.09 0.474 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.01 0.938 – 1.1 0.72 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.06 0.918 – 1.23 0.415 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.09 0.848 – 1.41 0.488 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.03 0.84 – 1.27 0.768 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 1.03 0.846 – 1.25 0.776 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.3 1.04 – 1.61 0.0186 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.18 1.13 – 1.22 3.26e-18 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.03 0.991 – 1.07 0.144 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 1.03 0.991 – 1.07 0.144 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 0.981 0.96 – 1 0.0921 8628 86999 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1 0.961 – 1.04 0.998 2668 26664 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.05 0.964 – 1.13 0.283 629 6367 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 0.892 0.83 – 0.958 0.00178 840 8475 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 0.832 0.632 – 1.09 0.189 55 538 exclusion phecode
010 Tuberculosis Infectious Diseases 0.857 0.73 – 1.01 0.0579 160 1613 exclusion phecode
038 Septicemia Infectious Diseases 1.02 0.984 – 1.05 0.322 3968 40796 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1 0.935 – 1.08 0.906 805 8283 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.05 0.954 – 1.15 0.332 480 4853 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.01 0.987 – 1.03 0.558 11640 118070 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.02 0.979 – 1.05 0.404 3032 30713 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 0.968 0.919 – 1.02 0.214 1600 16096 exclusion phecode
041.4 E. coli Infectious Diseases 1.01 0.971 – 1.05 0.591 2635 26875 exclusion phecode
053 Herpes zoster Infectious Diseases 1.01 0.906 – 1.12 0.912 398 4051 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.06 0.851 – 1.32 0.595 92 926 exclusion phecode
054 Herpes simplex Infectious Diseases 0.941 0.814 – 1.09 0.411 206 2064 exclusion phecode
070 Viral hepatitis Infectious Diseases 0.963 0.884 – 1.05 0.391 579 5823 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.15 0.896 – 1.47 0.273 67 680 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.992 0.83 – 1.18 0.925 130 1303 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 0.948 0.835 – 1.08 0.409 249 2540 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.1 0.973 – 1.24 0.129 271 2730 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 0.932 0.842 – 1.03 0.171 421 4213 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.02 0.866 – 1.21 0.792 146 1441 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.07 0.887 – 1.29 0.491 116 1147 exclusion phecode
078 Viral warts & HPV Infectious Diseases 1.04 0.971 – 1.11 0.276 994 9901 exclusion phecode
079 Viral infection Infectious Diseases 0.988 0.95 – 1.03 0.529 2723 27349 exclusion phecode
079.1 Varicella infection Infectious Diseases 1.29 1 – 1.65 0.0459 63 632 exclusion phecode
080 Postoperative infection Infectious Diseases 1.02 0.991 – 1.06 0.154 4333 43968 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 0.97 0.93 – 1.01 0.153 2424 24240 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.03 0.824 – 1.29 0.779 71 699 exclusion phecode
1000 Burns Injuries & Poisonings 1.05 0.964 – 1.14 0.264 572 5689 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 1.06 0.996 – 1.12 0.0698 1173 11794 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 0.996 0.969 – 1.02 0.787 5383 53819 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.05 0.926 – 1.18 0.474 294 2943 exclusion phecode
1005 Other symptoms Injuries & Poisonings 0.964 0.912 – 1.02 0.198 1377 14171 exclusion phecode
1006 Crushing injury Injuries & Poisonings 0.877 0.769 – 1 0.0493 249 2492 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 0.939 0.823 – 1.07 0.357 249 2504 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 0.981 0.919 – 1.05 0.559 996 9892 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 1.01 0.986 – 1.03 0.469 8332 83342 exclusion phecode
1010 Other tests Injuries & Poisonings 0.983 0.957 – 1.01 0.223 5772 58416 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.983 0.962 – 1 0.118 8864 89744 exclusion phecode
1012 Late effect Injuries & Poisonings 0.915 0.744 – 1.13 0.4 102 1035 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.03 0.911 – 1.16 0.665 308 3101 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.956 0.754 – 1.21 0.708 66 650 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 1.01 0.976 – 1.04 0.65 4121 41613 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1 0.984 – 1.02 0.969 15597 156439 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.991 0.875 – 1.12 0.892 273 2747 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 1.03 0.904 – 1.16 0.691 267 2687 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.09 0.857 – 1.39 0.48 71 741 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.06 0.893 – 1.27 0.493 137 1374 exclusion phecode
112 Candidiasis Infectious Diseases 0.982 0.938 – 1.03 0.434 2070 20879 exclusion phecode
117 Mycoses Infectious Diseases 1.03 0.912 – 1.17 0.617 265 2662 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.06 0.902 – 1.24 0.496 159 1619 exclusion phecode
130 Spirochetal infection Infectious Diseases 1.07 0.853 – 1.35 0.551 77 784 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 1.24 0.976 – 1.56 0.0787 69 675 exclusion phecode
134 Helminthiases Infectious Diseases 1.08 0.903 – 1.3 0.386 126 1249 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.11 0.909 – 1.35 0.312 106 1044 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.87 0.749 – 1.01 0.0659 198 2012 exclusion phecode
145 Cancer of mouth Neoplasms 0.966 0.889 – 1.05 0.415 628 6249 exclusion phecode
145.2 Cancer of tongue Neoplasms 0.963 0.857 – 1.08 0.533 303 3014 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.89 0.724 – 1.09 0.269 102 1027 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.1 0.822 – 1.46 0.535 52 526 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.01 0.932 – 1.1 0.786 621 6152 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.03 0.901 – 1.17 0.7 247 2459 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.05 0.927 – 1.2 0.42 262 2537 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.13 0.88 – 1.45 0.335 56 559 exclusion phecode
150 Cancer of esophagus Neoplasms 1.04 0.967 – 1.12 0.276 742 7354 exclusion phecode
151 Cancer of stomach Neoplasms 0.996 0.912 – 1.09 0.928 552 5516 exclusion phecode
153 Colorectal cancer Neoplasms 0.997 0.967 – 1.03 0.861 4443 44563 exclusion phecode
153.2 Colon cancer Neoplasms 1 0.968 – 1.04 0.797 3009 30226 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.992 0.948 – 1.04 0.716 2103 21040 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.973 0.877 – 1.08 0.608 391 3881 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.854 0.721 – 1.01 0.0667 153 1517 exclusion phecode
157 Pancreatic cancer Neoplasms 1.03 0.953 – 1.12 0.419 642 6419 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.05 0.984 – 1.12 0.14 1029 10409 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.998 0.97 – 1.03 0.879 5395 54285 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.07 0.924 – 1.24 0.359 186 1847 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.04 0.897 – 1.2 0.618 201 2003 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.12 0.971 – 1.3 0.118 192 1909 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.941 0.719 – 1.23 0.659 59 584 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1 0.963 – 1.04 0.952 2741 27442 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 0.98 0.937 – 1.02 0.363 2168 21720 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 0.865 0.784 – 0.954 0.00371 423 4270 exclusion phecode
170.1 Bone cancer Neoplasms 0.927 0.769 – 1.12 0.427 125 1268 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 0.82 0.733 – 0.918 0.000559 323 3235 exclusion phecode
172 Skin cancer Neoplasms 1.01 0.991 – 1.03 0.356 13109 131813 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.01 0.967 – 1.05 0.732 2614 26270 exclusion phecode
172.11 Melanomas of skin Neoplasms 1.01 0.967 – 1.05 0.739 2645 26590 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1.01 0.994 – 1.03 0.171 10674 107308 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.979 0.903 – 1.06 0.609 645 6503 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.1 0.946 – 1.29 0.208 177 1783 exclusion phecode
174 Breast cancer Neoplasms 1.01 0.992 – 1.03 0.272 12667 126544 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1.01 0.991 – 1.03 0.308 12476 124506 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.01 0.987 – 1.03 0.526 11757 117502 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.17 0.973 – 1.42 0.0943 115 1147 exclusion phecode
175 Acquired absence of breast Neoplasms 1.02 0.975 – 1.06 0.445 2400 24010 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.01 0.965 – 1.05 0.721 2174 21747 exclusion phecode
180.1 Cervical cancer Neoplasms 1.01 0.896 – 1.14 0.851 272 2720 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.999 0.955 – 1.04 0.958 2078 20784 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 1.04 0.985 – 1.1 0.147 1282 12836 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.01 0.958 – 1.07 0.659 1378 13772 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.02 0.957 – 1.09 0.514 967 9667 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.03 0.964 – 1.1 0.375 939 9387 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.01 0.9 – 1.13 0.872 305 3049 exclusion phecode
187 Cancer of other male genital organs Neoplasms 0.984 0.892 – 1.09 0.757 410 4485 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.925 0.723 – 1.18 0.533 67 700 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.967 0.857 – 1.09 0.591 277 2868 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.866 0.699 – 1.07 0.19 83 1098 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.01 0.973 – 1.04 0.707 3670 40219 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.978 0.917 – 1.04 0.506 1017 10432 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.97 0.908 – 1.04 0.368 978 10049 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.02 0.793 – 1.31 0.879 65 635 exclusion phecode
189.2 Cancer of bladder Neoplasms 1 0.961 – 1.05 0.829 2157 23256 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.986 0.941 – 1.03 0.557 1917 20654 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.11 0.928 – 1.33 0.25 129 1379 exclusion phecode
190 Cancer of eye Neoplasms 0.972 0.829 – 1.14 0.724 168 1718 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.978 0.904 – 1.06 0.586 673 6723 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 1.01 0.929 – 1.1 0.782 552 5524 exclusion phecode
191.11 Cancer of brain Neoplasms 0.997 0.912 – 1.09 0.951 516 5125 exclusion phecode
193 Thyroid cancer Neoplasms 1.03 0.919 – 1.15 0.648 343 3429 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.06 0.86 – 1.3 0.606 92 924 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.02 1 – 1.04 0.0189 14629 163267 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.02 1 – 1.04 0.015 13951 157346 exclusion phecode
197 Chemotherapy Neoplasms 0.985 0.971 – 0.999 0.0408 20766 211219 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1 0.983 – 1.03 0.699 8835 94427 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.01 0.977 – 1.03 0.716 5113 53174 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.02 0.977 – 1.07 0.353 2151 22398 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.05 0.996 – 1.11 0.0723 1506 15343 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 0.997 0.957 – 1.04 0.878 2522 26301 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.07 0.994 – 1.15 0.0739 816 8370 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.04 0.987 – 1.09 0.153 1674 21271 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.15 0.993 – 1.34 0.0617 183 1861 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 0.971 0.918 – 1.03 0.293 1372 14151 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.09 0.883 – 1.34 0.425 94 937 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.07 1 – 1.15 0.037 964 9657 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.02 0.917 – 1.14 0.709 372 3763 exclusion phecode
201 Hodgkin's disease Neoplasms 1.05 0.923 – 1.19 0.478 255 2559 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.976 0.935 – 1.02 0.284 2204 22197 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.971 0.925 – 1.02 0.239 1750 17660 exclusion phecode
202.21 Nodular lymphoma Neoplasms 0.88 0.788 – 0.982 0.0228 357 3573 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.02 0.932 – 1.11 0.698 563 5686 exclusion phecode
204 Leukemia Neoplasms 1 0.952 – 1.06 0.93 1604 16230 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 0.966 0.885 – 1.05 0.439 556 5626 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.834 0.639 – 1.09 0.182 55 548 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.998 0.909 – 1.1 0.963 487 4944 exclusion phecode
204.2 Myeloid leukemia Neoplasms 0.973 0.884 – 1.07 0.576 451 4512 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.95 0.848 – 1.07 0.381 323 3211 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.06 0.892 – 1.26 0.509 140 1416 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.01 0.926 – 1.11 0.79 532 5411 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1.02 1 – 1.03 0.0278 19201 187735 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.939 0.878 – 1 0.0627 956 9632 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.989 0.961 – 1.02 0.441 5134 51636 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1 0.897 – 1.12 0.98 340 3402 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.983 0.876 – 1.1 0.777 313 3154 exclusion phecode
214 Lipoma Neoplasms 0.998 0.972 – 1.02 0.864 6099 61135 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.01 0.982 – 1.04 0.417 4503 45137 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.01 0.949 – 1.07 0.755 1093 10892 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.987 0.964 – 1.01 0.288 7538 75658 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.07 0.986 – 1.17 0.103 572 6196 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 1.1 1.01 – 1.2 0.0371 537 5834 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.999 0.978 – 1.02 0.904 10023 100200 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.999 0.979 – 1.02 0.898 10241 102376 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.03 0.925 – 1.15 0.576 355 3548 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 1.02 0.969 – 1.08 0.421 1445 14483 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.03 0.899 – 1.19 0.639 220 2196 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.989 0.834 – 1.17 0.899 144 1600 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.93 0.791 – 1.09 0.376 164 1689 exclusion phecode
224 Benign neoplasm of eye Neoplasms 1.18 0.987 – 1.41 0.0686 126 1275 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.13 0.88 – 1.45 0.341 67 669 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.02 0.948 – 1.1 0.603 800 8046 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.01 0.94 – 1.09 0.737 758 7648 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.24 0.952 – 1.62 0.11 59 586 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.983 0.868 – 1.11 0.792 263 2654 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.03 0.958 – 1.1 0.443 838 8532 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.02 0.874 – 1.18 0.821 174 1827 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.02 0.915 – 1.14 0.719 367 3682 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.06 0.944 – 1.19 0.32 300 3056 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.988 0.938 – 1.04 0.638 1566 15727 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.989 0.948 – 1.03 0.616 2363 23679 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.989 0.91 – 1.07 0.792 597 5972 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.984 0.924 – 1.05 0.604 1096 11017 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.967 0.88 – 1.06 0.484 468 4663 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.998 0.921 – 1.08 0.963 668 6745 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.923 0.88 – 0.969 0.00112 1832 18353 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.892 0.809 – 0.984 0.0231 449 4520 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.05 0.847 – 1.29 0.677 91 908 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.843 0.707 – 1.01 0.058 135 1362 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 0.982 0.965 – 0.999 0.0339 14460 143920 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.999 0.939 – 1.06 0.977 1096 10994 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.95 0.781 – 1.15 0.603 100 1006 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.981 0.964 – 0.998 0.0322 13793 137836 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.846 0.749 – 0.956 0.00724 288 2860 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.875 0.761 – 1.01 0.061 218 2172 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.859 0.745 – 0.99 0.0363 210 2093 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 0.92 0.831 – 1.02 0.11 394 3951 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 0.991 0.977 – 1.01 0.253 19235 181652 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.988 0.949 – 1.03 0.544 2700 27018 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.971 0.846 – 1.11 0.673 232 2348 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.872 0.69 – 1.1 0.249 75 751 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.928 0.844 – 1.02 0.123 463 4643 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.05 0.894 – 1.24 0.534 157 1568 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.989 0.974 – 1 0.163 17307 165976 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.845 0.693 – 1.03 0.0955 101 1025 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.928 0.801 – 1.08 0.325 192 1951 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.951 0.89 – 1.02 0.138 957 9628 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.02 0.929 – 1.12 0.699 494 4924 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.05 0.972 – 1.14 0.203 663 6693 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.11 0.981 – 1.27 0.0962 255 2600 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.02 0.919 – 1.13 0.737 409 4101 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.949 0.792 – 1.14 0.576 131 1295 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.964 0.864 – 1.08 0.508 342 3401 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.952 0.899 – 1.01 0.0893 1295 12959 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.05 0.983 – 1.13 0.141 914 9161 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.993 0.926 – 1.06 0.844 863 8629 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.976 0.906 – 1.05 0.513 773 7735 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.03 0.862 – 1.22 0.773 138 1401 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.03 0.95 – 1.12 0.475 660 6676 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.03 0.891 – 1.2 0.661 185 1842 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.02 0.828 – 1.25 0.871 94 938 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.16 1.02 – 1.32 0.0272 251 2561 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.934 0.751 – 1.16 0.542 91 903 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.904 0.762 – 1.07 0.244 150 1545 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.993 0.915 – 1.08 0.865 621 6280 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.854 0.731 – 0.998 0.0478 175 1775 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.858 0.699 – 1.05 0.14 103 1022 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.831 0.657 – 1.05 0.122 73 747 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.05 0.939 – 1.17 0.408 355 3565 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.04 0.935 – 1.16 0.459 354 3553 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 1.1 0.965 – 1.26 0.152 240 2397 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.15 0.997 – 1.32 0.0557 209 2088 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 0.917 0.778 – 1.08 0.298 151 1574 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.919 0.776 – 1.09 0.327 143 1495 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.06 0.864 – 1.3 0.577 96 998 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.914 0.772 – 1.08 0.293 147 1487 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.09 0.938 – 1.26 0.268 200 1965 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.04 0.965 – 1.11 0.317 807 8155 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.04 0.983 – 1.11 0.161 1176 11771 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.07 0.988 – 1.15 0.098 738 7383 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.965 0.876 – 1.06 0.471 439 4409 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.774 0.611 – 0.979 0.0323 77 761 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.89 0.779 – 1.02 0.0887 237 2381 exclusion phecode
269 Proteinuria Endocrine/metabolic 0.976 0.873 – 1.09 0.672 334 3303 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.97 0.86 – 1.09 0.618 292 2950 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.987 0.867 – 1.12 0.837 252 2525 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.01 0.869 – 1.18 0.89 184 1853 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1.38 1.13 – 1.67 0.00131 111 1105 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.996 0.776 – 1.28 0.975 66 672 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.02 0.865 – 1.2 0.813 158 1582 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.952 0.798 – 1.14 0.583 137 1372 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.01 0.998 – 1.02 0.0954 33691 231345 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.01 0.998 – 1.02 0.0896 33620 231116 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.01 0.996 – 1.02 0.181 31257 224006 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.721 0.55 – 0.945 0.0177 55 560 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.09 0.921 – 1.28 0.326 155 1600 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.07 0.934 – 1.23 0.324 208 2047 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.01 0.973 – 1.04 0.684 3557 35951 exclusion phecode
274.1 Gout Endocrine/metabolic 1.01 0.97 – 1.05 0.715 3010 30536 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.08 0.885 – 1.32 0.443 106 1087 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.959 0.882 – 1.04 0.327 604 5978 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.973 0.892 – 1.06 0.544 551 5449 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1 0.958 – 1.05 0.888 2027 20607 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 1.03 0.945 – 1.11 0.551 639 6377 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 0.966 0.867 – 1.08 0.524 365 3661 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.982 0.924 – 1.04 0.564 1143 11754 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.07 0.908 – 1.27 0.407 162 1676 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.01 0.986 – 1.04 0.385 6994 71224 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.01 0.982 – 1.05 0.377 3914 39969 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.04 0.908 – 1.19 0.571 229 2327 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.01 0.966 – 1.06 0.571 1747 17823 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.03 0.962 – 1.1 0.394 909 9435 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.02 0.964 – 1.08 0.518 1380 13970 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.06 0.997 – 1.13 0.064 1114 11350 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.05 0.983 – 1.12 0.154 1012 10321 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.09 0.904 – 1.32 0.366 110 1097 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.01 0.971 – 1.05 0.61 2721 27640 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 0.959 0.87 – 1.06 0.403 446 4420 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.11 0.922 – 1.33 0.277 128 1267 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 0.977 0.912 – 1.05 0.504 883 8798 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.965 0.864 – 1.08 0.526 345 3533 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.884 0.77 – 1.02 0.0803 225 2238 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1 0.985 – 1.03 0.639 10582 106550 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.01 0.987 – 1.03 0.5 10420 104941 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 1.12 0.898 – 1.4 0.31 84 834 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.846 0.659 – 1.09 0.188 65 650 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1 0.878 – 1.14 0.99 244 2458 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 0.913 0.792 – 1.05 0.214 204 2058 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.914 0.766 – 1.09 0.323 135 1366 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.14 0.99 – 1.32 0.0691 197 2384 exclusion phecode
280 Iron deficiency anemias Hematopoietic 0.994 0.97 – 1.02 0.607 7460 74979 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.991 0.967 – 1.02 0.463 7172 71990 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.04 0.939 – 1.14 0.476 440 4495 exclusion phecode
281 Other deficiency anemia Hematopoietic 0.988 0.928 – 1.05 0.704 1091 10958 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 0.99 0.929 – 1.06 0.77 1045 10510 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.03 0.955 – 1.11 0.441 733 7415 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.941 0.802 – 1.1 0.454 176 1745 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 0.867 0.741 – 1.01 0.0724 180 1794 exclusion phecode
281.9 Deficiency anemias Hematopoietic 0.871 0.668 – 1.14 0.307 54 531 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.21 1.02 – 1.44 0.0315 145 1481 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.35 1.02 – 1.78 0.0338 54 557 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.12 0.889 – 1.41 0.339 83 837 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.1 0.919 – 1.32 0.292 132 1350 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.05 0.861 – 1.29 0.617 102 1031 exclusion phecode
284 Aplastic anemia Hematopoietic 0.974 0.881 – 1.08 0.604 420 4229 exclusion phecode
285 Other anemias Hematopoietic 0.993 0.975 – 1.01 0.482 11725 118973 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.965 0.851 – 1.09 0.577 264 2677 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 0.904 0.835 – 0.979 0.0129 656 6833 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.926 0.834 – 1.03 0.147 376 4062 exclusion phecode
286 Coagulation defects Hematopoietic 0.966 0.902 – 1.03 0.324 896 9041 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.991 0.9 – 1.09 0.849 450 4541 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.944 0.761 – 1.17 0.603 93 949 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.08 0.961 – 1.22 0.189 289 2912 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 0.912 0.707 – 1.18 0.479 61 623 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.89 0.702 – 1.13 0.334 79 831 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.96 0.865 – 1.06 0.436 382 3785 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.982 0.932 – 1.03 0.477 1582 16149 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.03 0.862 – 1.24 0.723 125 1276 exclusion phecode
287.2 Allergic purpura Hematopoietic 1.43 1.09 – 1.89 0.0102 51 501 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 0.969 0.919 – 1.02 0.239 1487 15189 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 0.99 0.895 – 1.1 0.849 409 4110 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.876 0.692 – 1.11 0.271 69 734 exclusion phecode
288 Diseases of white blood cells Hematopoietic 0.99 0.957 – 1.02 0.575 3617 37058 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 0.986 0.95 – 1.02 0.473 3040 31196 exclusion phecode
288.11 Neutropenia Hematopoietic 0.987 0.951 – 1.02 0.48 3048 31276 exclusion phecode
288.3 Eosinophilia Hematopoietic 0.979 0.763 – 1.26 0.869 68 693 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.04 0.971 – 1.12 0.255 846 8443 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.08 0.955 – 1.22 0.222 287 2853 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.01 0.973 – 1.06 0.497 2496 25599 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1.05 0.962 – 1.15 0.267 505 5032 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 0.992 0.876 – 1.12 0.898 285 2850 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 0.937 0.753 – 1.17 0.559 88 879 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.992 0.946 – 1.04 0.744 1856 18694 exclusion phecode
290.1 Dementias Mental Disorders 0.988 0.924 – 1.06 0.712 967 9734 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.929 0.84 – 1.03 0.155 420 4178 exclusion phecode
290.16 Vascular dementia Mental Disorders 1.06 0.911 – 1.23 0.464 190 1937 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.995 0.918 – 1.08 0.911 623 6293 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.06 0.836 – 1.35 0.624 69 699 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.03 0.954 – 1.1 0.496 811 8216 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.01 0.844 – 1.2 0.931 130 1309 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.11 0.981 – 1.25 0.0997 279 2797 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 0.991 0.896 – 1.1 0.858 419 4292 exclusion phecode
292 Neurological disorders Mental Disorders 1.05 1.01 – 1.08 0.0041 4465 45091 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.06 1 – 1.11 0.045 1467 14732 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 1.14 0.984 – 1.32 0.0815 185 1851 exclusion phecode
292.3 Memory loss Mental Disorders 1.05 0.97 – 1.14 0.223 676 6824 exclusion phecode
292.4 Altered mental status Mental Disorders 1.06 1.01 – 1.11 0.0104 2095 21208 exclusion phecode
292.6 Hallucinations Mental Disorders 0.969 0.86 – 1.09 0.603 301 3026 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.03 0.98 – 1.07 0.281 2022 20343 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.03 0.962 – 1.1 0.393 888 8861 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1 0.933 – 1.07 0.968 828 8338 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.04 0.957 – 1.14 0.344 567 5677 exclusion phecode
295.2 Paranoid disorders Mental Disorders 0.95 0.816 – 1.11 0.506 174 1763 exclusion phecode
295.3 Psychosis Mental Disorders 0.952 0.813 – 1.11 0.541 167 1697 exclusion phecode
296 Mood disorders Mental Disorders 1 0.984 – 1.02 0.797 12155 122462 exclusion phecode
296.1 Bipolar Mental Disorders 1.02 0.954 – 1.08 0.611 1037 10496 exclusion phecode
296.2 Depression Mental Disorders 1 0.982 – 1.02 0.904 11531 116194 exclusion phecode
296.22 Major depressive disorder Mental Disorders 0.994 0.892 – 1.11 0.919 354 3561 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1 0.891 – 1.12 0.999 305 3044 exclusion phecode
300 Anxiety disorders Mental Disorders 0.997 0.972 – 1.02 0.813 6722 67719 exclusion phecode
300.1 Anxiety disorder Mental Disorders 0.995 0.969 – 1.02 0.715 6205 62581 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 0.996 0.843 – 1.18 0.964 146 1483 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.03 0.95 – 1.11 0.507 693 6996 exclusion phecode
300.13 Phobia Mental Disorders 1.01 0.917 – 1.1 0.888 492 4969 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.07 0.895 – 1.27 0.474 139 1390 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.16 0.884 – 1.53 0.282 53 523 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 0.997 0.828 – 1.2 0.972 124 1222 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.01 0.829 – 1.23 0.937 112 1124 exclusion phecode
301 Personality disorders Mental Disorders 1.06 0.944 – 1.18 0.335 329 3303 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.11 0.917 – 1.33 0.294 119 1183 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 1.02 0.895 – 1.17 0.743 243 2740 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.967 0.879 – 1.06 0.495 462 4628 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.977 0.876 – 1.09 0.676 345 3465 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.931 0.772 – 1.12 0.453 123 1218 exclusion phecode
304 Adjustment reaction Mental Disorders 1.05 0.928 – 1.18 0.448 290 2914 exclusion phecode
305.2 Eating disorder Mental Disorders 1.22 0.981 – 1.52 0.0735 89 898 exclusion phecode
306 Other mental disorder Mental Disorders 1 0.988 – 1.01 0.895 27059 226107 exclusion phecode
306.9 Tension headache Mental Disorders 1.07 0.949 – 1.2 0.283 313 3131 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 1.1 0.876 – 1.38 0.411 74 758 exclusion phecode
313.3 Autism Mental Disorders 1.06 0.802 – 1.39 0.697 51 532 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.07 0.962 – 1.2 0.204 343 3430 exclusion phecode
315.1 Learning disorder Mental Disorders 0.992 0.844 – 1.17 0.919 161 1583 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.931 0.751 – 1.16 0.518 86 857 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1 0.972 – 1.03 0.996 5184 51914 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.767 0.59 – 0.998 0.048 57 587 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1 0.982 – 1.02 0.96 12364 124079 exclusion phecode
317.1 Alcoholism Mental Disorders 1 0.983 – 1.03 0.661 8634 86893 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 0.96 0.894 – 1.03 0.259 823 8183 exclusion phecode
318 Tobacco use disorder Mental Disorders 1 0.989 – 1.02 0.638 18932 181973 exclusion phecode
320 Meningitis Neurological 1.01 0.918 – 1.11 0.815 438 4386 exclusion phecode
323 Encephalitis Neurological 1.03 0.916 – 1.15 0.664 333 3368 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 1.37 1.09 – 1.74 0.00828 73 730 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 0.963 0.853 – 1.09 0.537 284 2867 exclusion phecode
327 Sleep disorders Neurological 1.01 0.953 – 1.08 0.672 1133 11377 exclusion phecode
327.3 Sleep apnea Neurological 0.986 0.956 – 1.02 0.379 4302 43266 exclusion phecode
327.4 Insomnia Neurological 0.922 0.784 – 1.08 0.323 159 1636 exclusion phecode
327.41 Organic or persistent insomnia Neurological 0.865 0.726 – 1.03 0.103 132 1370 exclusion phecode
331 Other cerebral degenerations Neurological 0.985 0.926 – 1.05 0.639 1110 11110 exclusion phecode
331.1 Hydrocephalus Neurological 0.969 0.883 – 1.06 0.502 489 4920 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 0.975 0.881 – 1.08 0.632 417 4140 exclusion phecode
332 Parkinson's disease Neurological 0.991 0.931 – 1.06 0.785 1082 10930 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.06 0.985 – 1.13 0.124 874 8789 exclusion phecode
333.1 Essential tremor Neurological 1.12 0.976 – 1.3 0.104 210 2116 exclusion phecode
333.2 Myoclonus Neurological 1.04 0.84 – 1.28 0.738 93 936 exclusion phecode
333.4 Torsion dystonia Neurological 1 0.885 – 1.14 0.946 252 2495 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1 0.954 – 1.05 0.913 1710 17732 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.1 0.908 – 1.33 0.335 112 1145 exclusion phecode
334.2 Anterior horn cell disease Neurological 0.984 0.861 – 1.13 0.816 237 2378 exclusion phecode
335 Multiple sclerosis Neurological 1 0.945 – 1.06 0.994 1329 13277 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 0.891 0.783 – 1.01 0.0807 260 2586 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.03 0.804 – 1.31 0.841 72 690 exclusion phecode
338 Pain Neurological 1 0.931 – 1.08 0.932 751 7604 exclusion phecode
338.1 Acute pain Neurological 0.995 0.898 – 1.1 0.917 384 3885 exclusion phecode
338.2 Chronic pain Neurological 0.989 0.89 – 1.1 0.842 372 3775 exclusion phecode
339 Other headache syndromes Neurological 0.996 0.972 – 1.02 0.707 7723 77304 exclusion phecode
340 Migraine Neurological 0.996 0.958 – 1.03 0.828 2832 28383 exclusion phecode
340.1 Migrain with aura Neurological 0.92 0.798 – 1.06 0.252 209 2097 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.01 0.889 – 1.15 0.865 249 2507 exclusion phecode
342 Hemiplegia Neurological 1.02 0.964 – 1.07 0.527 1465 14598 exclusion phecode
343 Infantile cerebral palsy Neurological 0.957 0.807 – 1.13 0.614 141 1427 exclusion phecode
344 Other paralytic syndromes Neurological 1.03 0.948 – 1.12 0.493 636 6461 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.999 0.971 – 1.03 0.968 4923 49377 exclusion phecode
345.1 Epilepsy Neurological 1.02 0.946 – 1.09 0.676 852 8507 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 0.99 0.898 – 1.09 0.84 432 4311 exclusion phecode
345.12 Partial epilepsy Neurological 1.15 1.02 – 1.3 0.0278 274 2722 exclusion phecode
345.3 Convulsions Neurological 1.03 0.989 – 1.08 0.148 2193 21924 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.827 0.693 – 0.986 0.0346 141 1416 exclusion phecode
348 Other conditions of brain Neurological 1.01 0.937 – 1.09 0.827 758 7640 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.09 0.966 – 1.24 0.157 260 2624 exclusion phecode
348.4 Cerebral cysts Neurological 0.878 0.738 – 1.05 0.144 130 1332 exclusion phecode
348.7 Coma Neurological 1.07 0.963 – 1.19 0.203 353 3519 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 0.923 0.807 – 1.06 0.239 243 2456 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.01 0.905 – 1.12 0.911 378 3805 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.06 0.947 – 1.18 0.317 333 3339 exclusion phecode
350 Abnormal movement Neurological 0.982 0.944 – 1.02 0.382 2592 26092 exclusion phecode
350.1 Abnormal involuntary movements Neurological 0.956 0.892 – 1.03 0.207 874 8673 exclusion phecode
350.2 Abnormality of gait Neurological 0.992 0.942 – 1.05 0.766 1542 15577 exclusion phecode
350.3 Lack of coordination Neurological 1.02 0.919 – 1.14 0.682 349 3549 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.955 0.736 – 1.24 0.731 54 534 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.01 0.993 – 1.03 0.228 12258 122955 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.02 0.968 – 1.08 0.412 1331 13478 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.01 0.917 – 1.11 0.846 452 4575 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.04 0.972 – 1.12 0.25 853 8643 exclusion phecode
353 Nerve root and plexus disorders Neurological 0.996 0.936 – 1.06 0.899 1079 11100 exclusion phecode
353.1 Nerve plexus lesions Neurological 1.05 0.866 – 1.27 0.637 112 1125 exclusion phecode
353.2 Nerve root lesions Neurological 1.05 0.802 – 1.38 0.718 57 559 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.837 0.703 – 0.996 0.0454 146 1476 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 0.981 0.927 – 1.04 0.508 1314 13294 exclusion phecode
358 Myoneural disorders Neurological 0.844 0.733 – 0.973 0.019 208 2066 exclusion phecode
358.1 Myasthenia gravis Neurological 0.839 0.724 – 0.973 0.0201 189 1876 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.946 0.857 – 1.04 0.268 455 4576 exclusion phecode
359.1 Muscular dystrophies Neurological 0.881 0.726 – 1.07 0.2 120 1202 exclusion phecode
359.2 Myopathy Neurological 0.985 0.881 – 1.1 0.791 352 3548 exclusion phecode
360 Disorders of the globe Sense Organs 1.01 0.9 – 1.13 0.891 328 3298 exclusion phecode
360.2 Progressive myopia Sense Organs 0.96 0.842 – 1.09 0.54 245 2457 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.984 0.948 – 1.02 0.378 3153 31680 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.992 0.938 – 1.05 0.769 1346 13577 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 1.03 0.799 – 1.32 0.84 64 662 exclusion phecode
362 Other retinal disorders Sense Organs 1.02 0.982 – 1.05 0.359 3747 37537 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.996 0.953 – 1.04 0.871 2137 21373 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.996 0.953 – 1.04 0.877 2134 21345 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.937 0.796 – 1.1 0.433 159 1579 exclusion phecode
362.31 Separation of retinal layers Sense Organs 0.91 0.74 – 1.12 0.373 99 970 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1 0.934 – 1.08 0.911 821 8251 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 1.04 0.896 – 1.21 0.594 179 1784 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.12 0.892 – 1.4 0.338 77 801 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.02 0.835 – 1.24 0.871 112 1130 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.938 0.803 – 1.1 0.422 168 1673 exclusion phecode
363.3 Chorioretinal scars Sense Organs 1.03 0.809 – 1.31 0.819 67 680 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.02 0.939 – 1.1 0.681 637 6386 exclusion phecode
364.1 Corneal opacity Sense Organs 0.987 0.795 – 1.23 0.904 87 882 exclusion phecode
364.2 Corneal edema Sense Organs 0.953 0.754 – 1.2 0.686 77 789 exclusion phecode
364.4 Corneal degenerations Sense Organs 1.05 0.906 – 1.21 0.534 200 1986 exclusion phecode
364.41 Keratoconus Sense Organs 0.974 0.782 – 1.21 0.815 86 857 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.972 0.845 – 1.12 0.687 208 2075 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 1.05 0.85 – 1.29 0.668 98 985 exclusion phecode
365 Glaucoma Sense Organs 0.987 0.956 – 1.02 0.404 4275 43029 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 1.01 0.942 – 1.07 0.877 999 10056 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 1.01 0.943 – 1.07 0.861 993 9999 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.941 0.869 – 1.02 0.13 694 6856 exclusion phecode
366 Cataract Sense Organs 0.989 0.975 – 1 0.161 19504 164933 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 1.07 0.843 – 1.35 0.587 68 690 exclusion phecode
366.2 Senile cataract Sense Organs 0.99 0.968 – 1.01 0.408 8052 80015 exclusion phecode
366.3 Traumatic cataract Sense Organs 0.959 0.785 – 1.17 0.68 101 982 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.01 0.97 – 1.06 0.589 2347 23630 exclusion phecode
367.1 Myopia Sense Organs 1.02 0.959 – 1.08 0.573 1218 12276 exclusion phecode
367.2 Astigmatism Sense Organs 0.947 0.815 – 1.1 0.482 185 1865 exclusion phecode
367.8 Hypermetropia Sense Organs 0.907 0.797 – 1.03 0.144 251 2486 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.04 0.958 – 1.12 0.379 697 7051 exclusion phecode
368 Visual disturbances Sense Organs 1.01 0.968 – 1.04 0.78 2905 29097 exclusion phecode
368.1 Amblyopia Sense Organs 0.994 0.909 – 1.09 0.898 523 5211 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.02 0.94 – 1.1 0.694 713 7140 exclusion phecode
368.3 Anisometropia Sense Organs 1.15 0.969 – 1.36 0.111 147 1509 exclusion phecode
368.4 Visual field defects Sense Organs 0.943 0.843 – 1.06 0.308 326 3245 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 1.02 0.939 – 1.11 0.635 604 6039 exclusion phecode
369 Infection of the eye Sense Organs 0.986 0.903 – 1.08 0.744 543 5442 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.939 0.782 – 1.13 0.498 124 1230 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 1 0.872 – 1.15 0.972 208 2093 exclusion phecode
370 Keratitis Sense Organs 1.02 0.899 – 1.15 0.776 282 2817 exclusion phecode
370.1 Corneal ulcer Sense Organs 1.02 0.857 – 1.22 0.814 139 1387 exclusion phecode
371 Inflammation of the eye Sense Organs 0.996 0.959 – 1.03 0.819 2999 29977 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.972 0.884 – 1.07 0.549 477 4734 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.995 0.954 – 1.04 0.825 2319 23174 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.02 0.946 – 1.1 0.594 738 7461 exclusion phecode
374 Other disorders of eyelids Sense Organs 1.01 0.98 – 1.04 0.577 5582 55734 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.996 0.933 – 1.06 0.897 1038 10317 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.984 0.937 – 1.03 0.525 1795 17939 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.986 0.944 – 1.03 0.532 2180 21693 exclusion phecode
375.2 Epiphora Sense Organs 1 0.938 – 1.08 0.887 890 8822 exclusion phecode
376 Disorders of the orbit Sense Organs 1.03 0.82 – 1.29 0.805 85 843 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.95 0.853 – 1.06 0.35 356 3573 exclusion phecode
377.1 Optic atrophy Sense Organs 0.915 0.689 – 1.21 0.538 54 561 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.989 0.82 – 1.19 0.906 125 1238 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.04 0.984 – 1.1 0.167 1384 13887 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.998 0.931 – 1.07 0.95 900 8976 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.04 0.904 – 1.2 0.567 206 2093 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.24 1.1 – 1.41 0.000691 266 2696 exclusion phecode
379 Other disorders of eye Sense Organs 1.01 0.972 – 1.04 0.727 3620 36255 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 1.02 0.967 – 1.08 0.431 1332 13371 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.966 0.92 – 1.01 0.166 1770 17722 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.14 0.903 – 1.44 0.269 71 700 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.03 0.926 – 1.14 0.618 389 3941 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.979 0.834 – 1.15 0.8 166 1661 exclusion phecode
380 Disorders of external ear Sense Organs 0.993 0.914 – 1.08 0.86 632 6256 exclusion phecode
380.1 Otitis externa Sense Organs 0.921 0.84 – 1.01 0.0777 502 5031 exclusion phecode
380.4 Impacted cerumen Sense Organs 1.03 0.922 – 1.15 0.612 355 3534 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.03 0.987 – 1.08 0.164 2104 21116 exclusion phecode
381.1 Otitis media Sense Organs 1.02 0.974 – 1.07 0.36 1729 17345 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1 0.936 – 1.08 0.905 833 8368 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 1.17 1.01 – 1.36 0.0322 190 1905 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.856 0.729 – 1 0.0564 168 1682 exclusion phecode
381.9 Otorrhea Sense Organs 1.06 0.936 – 1.19 0.369 274 2753 exclusion phecode
382 Otalgia Sense Organs 1.08 0.963 – 1.22 0.179 304 3053 exclusion phecode
383 Otosclerosis Sense Organs 0.96 0.854 – 1.08 0.497 306 3048 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.01 0.957 – 1.07 0.638 1282 12787 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.02 0.954 – 1.08 0.607 1029 10257 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.01 0.938 – 1.09 0.789 767 7695 exclusion phecode
385.3 Cholesteatoma Sense Organs 1.06 0.971 – 1.15 0.201 596 5955 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.978 0.855 – 1.12 0.75 234 2371 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.984 0.936 – 1.03 0.516 1697 17050 exclusion phecode
386.1 Meniere's disease Sense Organs 0.967 0.888 – 1.05 0.45 568 5679 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.998 0.898 – 1.11 0.976 370 3693 exclusion phecode
386.3 Labyrinthitis Sense Organs 0.976 0.904 – 1.05 0.53 741 7501 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.04 1.01 – 1.07 0.00935 4469 44908 exclusion phecode
388 Other disorders of ear Sense Organs 1.06 0.92 – 1.23 0.407 200 1981 exclusion phecode
389 Hearing loss Sense Organs 0.99 0.958 – 1.02 0.538 4056 40922 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.981 0.89 – 1.08 0.702 439 4460 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.01 0.918 – 1.12 0.815 441 4434 exclusion phecode
389.4 Tinnitus Sense Organs 0.979 0.893 – 1.07 0.648 498 5035 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 0.999 0.97 – 1.03 0.951 4770 47587 exclusion phecode
394.2 Mitral valve disease Circulatory System 0.994 0.957 – 1.03 0.758 2915 29110 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.01 0.955 – 1.07 0.67 1247 12423 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.02 0.955 – 1.08 0.589 1037 10291 exclusion phecode
395 Heart valve disorders Circulatory System 0.995 0.963 – 1.03 0.758 4106 41016 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1 0.964 – 1.04 0.895 2814 28118 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.03 0.91 – 1.17 0.622 268 2669 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1 0.823 – 1.21 0.997 102 1015 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.896 0.723 – 1.11 0.318 94 944 exclusion phecode
395.6 Heart valve replaced Circulatory System 0.985 0.934 – 1.04 0.59 1450 14448 exclusion phecode
396 Abnormal heart sounds Circulatory System 0.966 0.906 – 1.03 0.283 1020 10341 exclusion phecode
401 Hypertension Circulatory System 1.01 0.999 – 1.02 0.0713 71625 263926 exclusion phecode
401.1 Essential hypertension Circulatory System 1.01 0.999 – 1.02 0.0704 71405 263708 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 0.956 0.911 – 1 0.0643 1839 18554 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 0.891 0.8 – 0.993 0.0363 359 3601 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.975 0.925 – 1.03 0.348 1497 15096 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.01 0.856 – 1.2 0.865 142 1409 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 0.992 0.94 – 1.05 0.771 1432 14521 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.01 1 – 1.03 0.0271 30293 206480 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1 0.972 – 1.03 0.948 5013 49910 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.01 0.99 – 1.03 0.333 11571 108991 exclusion phecode
411.3 Angina pectoris Circulatory System 1.01 0.998 – 1.03 0.0935 15387 139892 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.02 1 – 1.03 0.039 19516 150474 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.04 0.958 – 1.12 0.374 682 6779 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.01 0.99 – 1.02 0.435 14743 127919 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.983 0.926 – 1.04 0.575 1179 11785 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1 0.955 – 1.05 0.885 1746 17612 exclusion phecode
414.2 ASCVD Circulatory System 1.03 0.806 – 1.31 0.82 69 704 exclusion phecode
415 Pulmonary heart disease Circulatory System 0.998 0.968 – 1.03 0.912 4324 43784 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.895 0.701 – 1.14 0.37 74 732 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.05 0.967 – 1.14 0.239 593 5843 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.03 0.938 – 1.14 0.494 444 4350 exclusion phecode
416 Cardiomegaly Circulatory System 1.02 0.984 – 1.07 0.249 2601 25984 exclusion phecode
418 Nonspecific chest pain Circulatory System 0.998 0.985 – 1.01 0.696 28010 265597 exclusion phecode
418.1 Precordial pain Circulatory System 0.951 0.919 – 0.985 0.00453 3480 34928 exclusion phecode
420 Carditis Circulatory System 1.02 0.976 – 1.07 0.352 2051 20530 exclusion phecode
420.1 Myocarditis Circulatory System 0.97 0.807 – 1.17 0.747 123 1243 exclusion phecode
420.2 Pericarditis Circulatory System 1.05 0.988 – 1.11 0.125 1304 13018 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.01 0.877 – 1.16 0.902 220 2165 exclusion phecode
420.22 Chronic pericarditis Circulatory System 0.96 0.793 – 1.16 0.676 112 1102 exclusion phecode
420.3 Endocarditis Circulatory System 0.961 0.889 – 1.04 0.313 698 7013 exclusion phecode
425 Cardiomyopathy Circulatory System 1.02 0.962 – 1.08 0.506 1238 12352 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.01 0.948 – 1.07 0.841 1203 12013 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.05 0.88 – 1.25 0.594 127 1298 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.06 0.902 – 1.24 0.485 157 1592 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.33 1.02 – 1.73 0.0353 59 578 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.02 0.994 – 1.05 0.14 6647 67016 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.01 0.966 – 1.06 0.626 2018 20426 exclusion phecode
426.21 First degree AV block Circulatory System 1.07 1 – 1.15 0.0461 936 9532 exclusion phecode
426.23 Second degree AV block Circulatory System 0.891 0.805 – 0.985 0.0245 426 4350 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 0.95 0.872 – 1.04 0.241 573 5669 exclusion phecode
426.25 Other heart block Circulatory System 1.16 0.964 – 1.39 0.116 122 1280 exclusion phecode
426.3 Bundle branch block Circulatory System 1.02 0.982 – 1.06 0.317 3220 32367 exclusion phecode
426.31 Right bundle branch block Circulatory System 0.991 0.939 – 1.05 0.756 1442 14484 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.05 0.998 – 1.1 0.0597 1686 16974 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.05 0.921 – 1.21 0.446 225 2285 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 0.749 0.578 – 0.971 0.0292 58 587 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.03 0.985 – 1.07 0.207 2383 23938 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.04 0.995 – 1.09 0.0804 2187 21999 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.01 0.995 – 1.02 0.22 23418 201897 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1 0.967 – 1.04 0.874 3118 31324 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.985 0.943 – 1.03 0.478 2284 23048 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.06 0.994 – 1.14 0.0717 905 9086 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.01 0.994 – 1.03 0.185 14074 129762 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.01 0.969 – 1.04 0.791 3090 31367 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.948 0.892 – 1.01 0.0864 1168 11570 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.06 0.952 – 1.19 0.278 337 3328 exclusion phecode
427.42 Cardiac arrest Circulatory System 0.928 0.868 – 0.992 0.0278 968 9605 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.991 0.926 – 1.06 0.79 912 9325 exclusion phecode
427.6 Premature beats Circulatory System 1.01 0.927 – 1.11 0.748 518 5225 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 0.959 0.791 – 1.16 0.668 113 1138 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.03 0.985 – 1.08 0.196 2123 21450 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.952 0.859 – 1.05 0.348 388 3939 exclusion phecode
427.9 Palpitations Circulatory System 1.01 0.973 – 1.04 0.725 3738 37612 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.04 1.01 – 1.07 0.00747 5419 54103 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.06 1.01 – 1.11 0.01 2042 20420 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.03 0.998 – 1.06 0.0703 4308 42974 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.04 0.963 – 1.13 0.308 692 7036 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 0.969 0.75 – 1.25 0.809 63 612 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.08 0.984 – 1.18 0.108 501 5116 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 0.907 0.782 – 1.05 0.192 193 1943 exclusion phecode
430 Intracranial hemorrhage Circulatory System 0.983 0.937 – 1.03 0.477 1828 18407 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.01 0.94 – 1.08 0.806 824 8255 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 0.934 0.867 – 1.01 0.0751 739 7448 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.04 0.91 – 1.18 0.583 249 2570 exclusion phecode
433 Cerebrovascular disease Circulatory System 1 0.982 – 1.03 0.711 8492 85059 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.954 0.897 – 1.01 0.13 1149 11432 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 0.985 0.855 – 1.14 0.837 219 2203 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.999 0.968 – 1.03 0.968 4114 41078 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.982 0.932 – 1.03 0.481 1634 16283 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.02 0.983 – 1.06 0.265 2812 28159 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.04 0.997 – 1.09 0.0699 2084 20808 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 0.961 0.867 – 1.07 0.448 392 3884 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.01 0.95 – 1.07 0.83 1247 12419 exclusion phecode
440 Atherosclerosis Circulatory System 0.995 0.941 – 1.05 0.87 1337 13315 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.05 0.867 – 1.27 0.621 111 1083 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.01 0.939 – 1.09 0.781 783 7773 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.02 0.901 – 1.15 0.771 277 2782 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.06 0.978 – 1.16 0.151 592 6033 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.07 0.941 – 1.21 0.315 275 2758 exclusion phecode
442 Other aneurysm Circulatory System 1.01 0.958 – 1.06 0.822 1817 18208 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.01 0.952 – 1.06 0.823 1394 13988 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.01 0.947 – 1.09 0.681 879 8866 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 0.97 0.796 – 1.18 0.765 98 974 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.931 0.794 – 1.09 0.385 163 1633 exclusion phecode
442.4 Arterial dissection Circulatory System 0.991 0.745 – 1.32 0.952 53 544 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.04 0.897 – 1.2 0.609 197 1993 exclusion phecode
443 Peripheral vascular disease Circulatory System 0.999 0.966 – 1.03 0.936 3824 38188 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 0.997 0.938 – 1.06 0.919 1131 11308 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.964 0.866 – 1.07 0.507 376 3737 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1 0.97 – 1.04 0.847 3592 35904 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1 0.959 – 1.04 0.981 2497 24968 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 0.931 0.87 – 0.997 0.0408 893 8935 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.921 0.843 – 1.01 0.0651 536 5327 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.04 0.971 – 1.12 0.243 800 8083 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 1 0.86 – 1.17 0.976 179 1839 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.04 0.935 – 1.15 0.492 379 3821 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.09 0.953 – 1.25 0.208 234 2343 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 0.977 0.923 – 1.03 0.433 1295 12873 exclusion phecode
447.1 Stricture of artery Circulatory System 0.954 0.889 – 1.02 0.192 843 8388 exclusion phecode
448 Disease of capillaries Circulatory System 1.13 0.949 – 1.35 0.168 131 1396 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.954 0.881 – 1.03 0.242 671 6917 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.01 0.976 – 1.04 0.618 3814 38811 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.02 0.982 – 1.05 0.353 3545 36161 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 0.959 0.878 – 1.05 0.353 549 5544 exclusion phecode
454 Varicose veins Circulatory System 0.998 0.979 – 1.02 0.852 11007 110606 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 0.995 0.976 – 1.01 0.636 11335 113852 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.981 0.902 – 1.07 0.645 612 6176 exclusion phecode
455 Hemorrhoids Circulatory System 0.997 0.984 – 1.01 0.708 22915 230639 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.05 0.899 – 1.22 0.544 180 1824 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.98 0.791 – 1.22 0.857 95 936 exclusion phecode
458 Hypotension Circulatory System 1.01 0.985 – 1.04 0.369 5581 56434 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 0.959 0.905 – 1.02 0.156 1286 12999 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.07 0.93 – 1.22 0.357 230 2289 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.01 0.973 – 1.04 0.65 3382 34216 exclusion phecode
459 Other disorders of circulatory system Circulatory System 0.994 0.978 – 1.01 0.488 15746 157149 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.07 0.906 – 1.27 0.42 137 1383 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 0.995 0.978 – 1.01 0.524 15586 155814 exclusion phecode
464 Acute sinusitis Respiratory 1.04 0.896 – 1.2 0.615 195 1927 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.02 0.976 – 1.06 0.39 2237 22482 exclusion phecode
465.2 Acute pharyngitis Respiratory 1.03 0.955 – 1.1 0.491 819 8207 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.969 0.825 – 1.14 0.695 161 1620 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.978 0.949 – 1.01 0.16 4568 45757 exclusion phecode
471 Nasal polyps Respiratory 1.03 0.996 – 1.07 0.0781 3213 32167 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.01 0.949 – 1.08 0.67 937 9452 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.03 0.986 – 1.07 0.204 2504 25031 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.13 0.924 – 1.38 0.236 100 1014 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.03 0.907 – 1.17 0.65 259 2594 exclusion phecode
473.4 Voice disturbance Respiratory 1.03 0.967 – 1.1 0.364 1061 10589 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1.02 0.968 – 1.07 0.511 1755 17572 exclusion phecode
474.1 Acute tonsillitis Respiratory 0.964 0.883 – 1.05 0.408 546 5452 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.07 1.01 – 1.14 0.0248 1110 11120 exclusion phecode
475 Chronic sinusitis Respiratory 1.02 0.978 – 1.06 0.372 2542 25466 exclusion phecode
476 Allergic rhinitis Respiratory 1.05 0.984 – 1.12 0.146 1032 10419 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.06 1.01 – 1.1 0.0106 2376 23838 exclusion phecode
478 Throat pain Respiratory 1.01 0.909 – 1.12 0.858 372 3730 exclusion phecode
479 Other upper respiratory disease Respiratory 0.995 0.963 – 1.03 0.756 3994 40014 exclusion phecode
480 Pneumonia Respiratory 1 0.985 – 1.03 0.636 10021 100856 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.01 0.983 – 1.03 0.517 6429 64823 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.01 0.983 – 1.04 0.458 5699 57469 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 0.901 0.72 – 1.13 0.361 89 908 exclusion phecode
480.2 Viral pneumonia Respiratory 1.05 0.833 – 1.33 0.663 69 706 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.941 0.766 – 1.16 0.563 96 966 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.922 0.856 – 0.993 0.0315 760 7690 exclusion phecode
481 Influenza Respiratory 1.02 0.906 – 1.14 0.769 323 3213 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.03 0.884 – 1.19 0.722 189 1902 exclusion phecode
495 Asthma Respiratory 1 0.987 – 1.01 0.975 25193 246934 exclusion phecode
495.2 Asthma with exacerbation Respiratory 0.989 0.869 – 1.12 0.864 249 2468 exclusion phecode
496 Chronic airway obstruction Respiratory 0.979 0.959 – 0.999 0.038 10136 99054 exclusion phecode
496.1 Emphysema Respiratory 1.03 0.975 – 1.08 0.329 1683 16925 exclusion phecode
496.2 Chronic bronchitis Respiratory 0.982 0.945 – 1.02 0.364 2887 28691 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 0.984 0.945 – 1.02 0.42 2652 26344 exclusion phecode
496.3 Bronchiectasis Respiratory 1.01 0.964 – 1.06 0.645 1833 18454 exclusion phecode
497 Bronchitis Respiratory 1.02 0.937 – 1.11 0.673 605 6140 exclusion phecode
500 Lung disease due to external agents Respiratory 0.9 0.81 – 1 0.0502 394 3923 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.816 0.642 – 1.04 0.0955 74 771 exclusion phecode
500.2 Pneumoconiosis Respiratory 0.852 0.742 – 0.979 0.0236 232 2265 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 0.982 0.907 – 1.06 0.66 636 6348 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.955 0.891 – 1.02 0.193 894 8909 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 0.959 0.875 – 1.05 0.376 496 4924 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.933 0.833 – 1.05 0.231 320 3190 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 0.947 0.728 – 1.23 0.684 58 603 exclusion phecode
506 Empyema and pneumothorax Respiratory 0.968 0.909 – 1.03 0.302 1106 11067 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1 0.976 – 1.03 0.868 6214 62527 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.02 0.972 – 1.07 0.433 1940 19461 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.985 0.945 – 1.03 0.457 2517 25333 exclusion phecode
509.1 Respiratory failure Respiratory 0.965 0.922 – 1.01 0.133 2000 20150 exclusion phecode
509.2 Respiratory insufficiency Respiratory 0.97 0.923 – 1.02 0.217 1755 17643 exclusion phecode
509.5 Respiratory arrest Respiratory 0.976 0.816 – 1.17 0.791 139 1400 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.05 0.944 – 1.17 0.367 376 3749 exclusion phecode
510 Other diseases of lung Respiratory 1.02 0.944 – 1.1 0.66 737 7371 exclusion phecode
512 Other symptoms of respiratory system Respiratory 0.995 0.973 – 1.02 0.65 8830 88637 exclusion phecode
512.1 Wheezing Respiratory 0.954 0.83 – 1.1 0.502 215 2157 exclusion phecode
512.2 Painful respiration Respiratory 0.959 0.829 – 1.11 0.578 206 2041 exclusion phecode
512.7 Shortness of breath Respiratory 0.988 0.961 – 1.02 0.377 5697 57363 exclusion phecode
512.8 Cough Respiratory 0.975 0.938 – 1.01 0.199 2810 28113 exclusion phecode
512.9 Other dyspnea Respiratory 1.07 0.998 – 1.15 0.0556 893 8945 exclusion phecode
513 Respiratory abnormalities Respiratory 0.969 0.892 – 1.05 0.464 603 5985 exclusion phecode
513.3 Hypoventilation Respiratory 1.25 0.996 – 1.57 0.054 83 808 exclusion phecode
513.4 Hyperventilation Respiratory 0.971 0.859 – 1.1 0.639 277 2752 exclusion phecode
513.8 Disorders of diaphragm Respiratory 0.99 0.838 – 1.17 0.909 148 1483 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.01 0.966 – 1.05 0.726 2393 24064 exclusion phecode
516 Abnormal sputum Respiratory 0.991 0.947 – 1.04 0.691 2080 20798 exclusion phecode
516.1 Hemoptysis Respiratory 1.01 0.962 – 1.05 0.762 2022 20221 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.01 0.987 – 1.03 0.467 9112 91653 exclusion phecode
519.2 Respiratory complications Respiratory 1.07 0.952 – 1.2 0.259 319 3181 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1 0.98 – 1.02 0.863 8612 86616 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.09 0.966 – 1.22 0.166 297 2997 exclusion phecode
520 Disorders of tooth development Digestive 0.995 0.951 – 1.04 0.836 2023 20171 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.993 0.759 – 1.3 0.958 52 527 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 1 0.96 – 1.04 0.952 2340 23351 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 0.987 0.95 – 1.02 0.488 2960 29817 exclusion phecode
521.1 Dental caries Digestive 0.99 0.953 – 1.03 0.588 2971 29926 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 0.97 0.924 – 1.02 0.23 1753 17520 exclusion phecode
522.5 Periapical abscess Digestive 0.992 0.934 – 1.05 0.785 1158 11571 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.02 0.965 – 1.07 0.564 1660 16600 exclusion phecode
523.1 Gingivitis Digestive 1.13 0.925 – 1.37 0.235 112 1111 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.02 0.962 – 1.09 0.469 1150 11535 exclusion phecode
523.31 Acute periodontitis Digestive 1.03 0.955 – 1.12 0.406 657 6611 exclusion phecode
523.32 Chronic periodontitis Digestive 0.999 0.916 – 1.09 0.979 552 5523 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.03 0.921 – 1.16 0.58 329 3265 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.04 0.922 – 1.17 0.538 303 3003 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.03 0.987 – 1.07 0.184 2619 26317 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.909 0.715 – 1.16 0.437 71 700 exclusion phecode
526 Diseases of the jaws Digestive 1.03 0.965 – 1.1 0.357 918 9170 exclusion phecode
526.1 Cysts of the jaws Digestive 1.01 0.9 – 1.13 0.905 325 3222 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.891 0.691 – 1.15 0.372 60 608 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.07 0.94 – 1.23 0.293 239 2398 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.07 0.94 – 1.23 0.293 232 2328 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 1.11 0.917 – 1.35 0.28 108 1080 exclusion phecode
526.9 Jaw disease NOS Digestive 1.02 0.894 – 1.17 0.729 230 2302 exclusion phecode
527 Diseases of the salivary glands Digestive 0.994 0.92 – 1.07 0.88 685 6840 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.03 0.823 – 1.29 0.788 83 830 exclusion phecode
527.2 Sialoadenitis Digestive 1.01 0.909 – 1.12 0.847 359 3610 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 0.971 0.753 – 1.25 0.82 61 608 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 0.987 0.818 – 1.19 0.892 119 1181 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.998 0.965 – 1.03 0.884 3811 38178 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.1 0.996 – 1.21 0.0607 461 4600 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.1 0.99 – 1.22 0.076 383 3822 exclusion phecode
528.12 Oral aphthae Digestive 1.13 0.906 – 1.42 0.271 83 829 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.05 0.898 – 1.22 0.554 177 1761 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.925 0.77 – 1.11 0.403 118 1202 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.941 0.761 – 1.16 0.578 93 926 exclusion phecode
528.5 Diseases of lips Digestive 0.957 0.884 – 1.04 0.271 671 6724 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 0.954 0.85 – 1.07 0.427 306 3025 exclusion phecode
528.7 Sialolithiasis Digestive 0.974 0.868 – 1.09 0.647 306 3098 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 0.938 0.884 – 0.995 0.033 1208 12136 exclusion phecode
529.1 Glossitis Digestive 0.967 0.859 – 1.09 0.572 289 2937 exclusion phecode
530 Diseases of esophagus Digestive 0.995 0.983 – 1.01 0.35 32736 274764 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.995 0.983 – 1.01 0.389 30585 268039 exclusion phecode
530.11 GERD Digestive 0.995 0.982 – 1.01 0.496 22157 222110 exclusion phecode
530.12 Ulcer of esophagus Digestive 0.982 0.954 – 1.01 0.227 5062 50715 exclusion phecode
530.14 Reflux esophagitis Digestive 1 0.981 – 1.02 0.91 10238 102581 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.994 0.945 – 1.05 0.815 1640 16453 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1.05 0.996 – 1.1 0.0703 1824 18245 exclusion phecode
530.5 Disorders of esophageal motility Digestive 0.96 0.885 – 1.04 0.329 623 6262 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.33 1.12 – 1.59 0.0015 148 1495 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.94 0.838 – 1.05 0.293 332 3333 exclusion phecode
530.9 Heartburn Digestive 1 0.959 – 1.05 0.9 2053 20652 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.981 0.957 – 1.01 0.135 6928 69501 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.05 0.969 – 1.14 0.225 616 6190 exclusion phecode
531.2 Gastric ulcer Digestive 0.987 0.956 – 1.02 0.434 4000 40099 exclusion phecode
531.3 Duodenal ulcer Digestive 0.973 0.937 – 1.01 0.162 2919 29296 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 0.858 0.776 – 0.948 0.00252 417 4137 exclusion phecode
532 Dysphagia Digestive 1.02 0.992 – 1.04 0.18 6304 63249 exclusion phecode
535 Gastritis and duodenitis Digestive 0.995 0.982 – 1.01 0.404 27504 257126 exclusion phecode
535.1 Acute gastritis Digestive 0.995 0.937 – 1.06 0.865 1154 11593 exclusion phecode
535.2 Atrophic gastritis Digestive 1.04 0.931 – 1.15 0.512 363 3590 exclusion phecode
535.6 Duodenitis Digestive 0.975 0.952 – 0.999 0.0374 7401 74220 exclusion phecode
535.8 Other specified gastritis Digestive 0.994 0.971 – 1.02 0.59 7928 79385 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.894 0.74 – 1.08 0.248 117 1169 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.99 0.872 – 1.12 0.882 256 2537 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 0.974 0.94 – 1.01 0.145 3312 33253 exclusion phecode
540 Appendiceal conditions Digestive 0.992 0.956 – 1.03 0.677 3035 30453 exclusion phecode
540.1 Appendicitis Digestive 0.998 0.96 – 1.04 0.912 2848 28560 exclusion phecode
540.11 Acute appendicitis Digestive 0.992 0.953 – 1.03 0.714 2556 25663 exclusion phecode
550 Abdominal hernia Digestive 1.01 0.996 – 1.02 0.27 44022 278757 exclusion phecode
550.1 Inguinal hernia Digestive 1.01 0.997 – 1.03 0.103 15000 119476 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1 0.988 – 1.01 0.869 25921 235248 exclusion phecode
550.3 Femoral hernia Digestive 0.976 0.901 – 1.06 0.546 641 6426 exclusion phecode
550.4 Umbilical hernia Digestive 1.01 0.973 – 1.04 0.709 3587 36206 exclusion phecode
550.5 Ventral hernia Digestive 1 0.966 – 1.04 0.96 3313 33738 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.01 0.977 – 1.04 0.622 4340 43749 exclusion phecode
555.1 Regional enteritis Digestive 0.967 0.92 – 1.02 0.183 1708 17097 exclusion phecode
555.2 Ulcerative colitis Digestive 1.02 0.979 – 1.05 0.405 3087 31262 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.05 0.956 – 1.15 0.309 515 5306 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.02 0.961 – 1.09 0.454 1021 10398 exclusion phecode
556.1 Ulceration of intestine Digestive 0.978 0.903 – 1.06 0.585 652 6592 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.885 0.786 – 0.997 0.0437 296 2956 exclusion phecode
557.1 Celiac disease Digestive 0.809 0.771 – 0.849 1.06e-17 1815 18150 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.01 0.99 – 1.02 0.44 15220 153129 exclusion phecode
559 Ileostomy status Digestive 0.987 0.938 – 1.04 0.628 1613 16194 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 0.972 0.94 – 1 0.0951 3824 38634 exclusion phecode
560.1 Paralytic ileus Digestive 1.01 0.919 – 1.11 0.861 490 5109 exclusion phecode
560.2 Impaction of intestine Digestive 0.866 0.763 – 0.983 0.0259 257 2631 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.97 0.903 – 1.04 0.409 819 8198 exclusion phecode
560.4 Other intestinal obstruction Digestive 0.975 0.941 – 1.01 0.171 3284 32994 exclusion phecode
561 Symptoms involving digestive system Digestive 0.99 0.974 – 1.01 0.234 15477 155906 exclusion phecode
561.1 Diarrhea Digestive 0.953 0.865 – 1.05 0.338 457 4579 exclusion phecode
561.2 Flatulence Digestive 1.01 0.96 – 1.06 0.698 1654 16666 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1.01 0.993 – 1.02 0.356 25997 208174 exclusion phecode
562.1 Diverticulosis Digestive 1.01 0.993 – 1.02 0.339 25957 208124 exclusion phecode
563 Constipation Digestive 1 0.982 – 1.02 0.827 9970 101591 exclusion phecode
564 Functional digestive disorders Digestive 0.989 0.975 – 1 0.126 21093 206698 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 0.985 0.958 – 1.01 0.28 5450 54687 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.03 0.979 – 1.09 0.25 1604 16199 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 0.988 0.971 – 1 0.163 14740 148800 exclusion phecode
565 Anal and rectal conditions Digestive 1 0.985 – 1.02 0.801 14153 144779 exclusion phecode
565.1 Anal and rectal polyp Digestive 1.01 0.987 – 1.04 0.368 7120 71947 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.02 0.949 – 1.09 0.645 898 9092 exclusion phecode
568 Other disorders of peritoneum Digestive 0.988 0.952 – 1.02 0.507 3166 32171 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.989 0.952 – 1.03 0.547 3011 30596 exclusion phecode
569 Other disorders of intestine Digestive 0.983 0.952 – 1.02 0.303 4062 41138 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.08 0.904 – 1.29 0.401 138 1455 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.03 0.934 – 1.13 0.58 466 4765 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 0.991 0.953 – 1.03 0.628 2890 29073 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 0.979 0.931 – 1.03 0.416 1654 16648 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.9 0.745 – 1.09 0.279 110 1115 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 0.993 0.874 – 1.13 0.91 256 2551 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.981 0.918 – 1.05 0.563 951 9542 exclusion phecode
571.81 Portal hypertension Digestive 0.967 0.884 – 1.06 0.463 516 5139 exclusion phecode
572 Ascites (non malignant) Digestive 0.987 0.937 – 1.04 0.626 1505 15168 exclusion phecode
573 Other disorders of liver Digestive 1.03 0.977 – 1.09 0.266 1456 14705 exclusion phecode
573.2 Liver replaced by transplant Digestive 0.902 0.736 – 1.11 0.322 95 935 exclusion phecode
573.3 Hepatomegaly Digestive 1.01 0.9 – 1.14 0.817 290 2898 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 0.973 0.907 – 1.04 0.436 867 8742 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 0.965 0.931 – 1 0.0472 3363 33957 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.17 1.01 – 1.36 0.0381 189 2022 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1 0.985 – 1.02 0.895 15385 154284 exclusion phecode
574.1 Cholelithiasis Digestive 0.997 0.979 – 1.01 0.739 13363 133984 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.02 0.971 – 1.08 0.371 1482 14825 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.02 0.99 – 1.05 0.206 5357 53695 exclusion phecode
574.2 Calculus of bile duct Digestive 1.04 0.998 – 1.08 0.0656 2584 25822 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.995 0.956 – 1.03 0.792 2704 27125 exclusion phecode
575 Other biliary tract disease Digestive 0.997 0.964 – 1.03 0.853 3788 38162 exclusion phecode
575.1 Cholangitis Digestive 0.925 0.842 – 1.02 0.103 476 4787 exclusion phecode
575.2 Obstruction of bile duct Digestive 0.98 0.909 – 1.06 0.603 754 7601 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 1.06 0.959 – 1.16 0.266 452 4528 exclusion phecode
575.7 Other disorders of gallbladder Digestive 0.988 0.935 – 1.04 0.672 1385 13951 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1 0.939 – 1.07 0.962 1019 10236 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.03 0.917 – 1.15 0.658 337 3436 exclusion phecode
577 Diseases of pancreas Digestive 0.972 0.934 – 1.01 0.167 2616 26203 exclusion phecode
577.1 Acute pancreatitis Digestive 0.977 0.932 – 1.02 0.321 1960 19613 exclusion phecode
577.2 Chronic pancreatitis Digestive 0.99 0.905 – 1.08 0.827 509 5040 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.936 0.841 – 1.04 0.222 358 3580 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.992 – 1.02 0.42 20079 202825 exclusion phecode
578.1 Hematemesis Digestive 1.01 0.966 – 1.06 0.616 1901 19164 exclusion phecode
578.2 Blood in stool Digestive 0.968 0.929 – 1.01 0.116 2555 25725 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.01 0.992 – 1.03 0.256 12737 128765 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1 0.975 – 1.03 0.838 5119 51850 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.03 0.975 – 1.08 0.301 1511 15285 exclusion phecode
579.2 Splenomegaly Digestive 1.03 0.927 – 1.14 0.611 406 4138 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.04 0.986 – 1.09 0.161 1610 16276 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.974 0.923 – 1.03 0.331 1483 14969 exclusion phecode
580.1 Glomerulonephritis Genitourinary 0.993 0.93 – 1.06 0.82 1015 10274 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.82 0.643 – 1.05 0.109 74 719 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.11 0.93 – 1.32 0.256 132 1324 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.991 0.924 – 1.06 0.812 842 8545 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.927 0.843 – 1.02 0.122 456 4578 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.962 0.843 – 1.1 0.56 239 2402 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.97 0.853 – 1.1 0.648 246 2470 exclusion phecode
585 Renal failure Genitourinary 1.02 0.992 – 1.04 0.172 6633 67783 exclusion phecode
585.1 Acute renal failure Genitourinary 1.02 0.99 – 1.05 0.187 4296 43955 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.05 0.991 – 1.11 0.103 1386 14212 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.992 0.952 – 1.03 0.698 2539 25757 exclusion phecode
585.31 Renal dialysis Genitourinary 0.954 0.869 – 1.05 0.317 483 4857 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 0.977 0.942 – 1.01 0.213 3192 32751 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.883 0.763 – 1.02 0.0969 193 2037 exclusion phecode
586.11 Small kidney Genitourinary 0.882 0.754 – 1.03 0.116 169 1753 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 0.996 0.938 – 1.06 0.894 1200 12227 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.931 0.744 – 1.16 0.532 77 778 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.921 0.859 – 0.989 0.0228 853 8927 exclusion phecode
587 Kidney replaced by transpant Genitourinary 0.924 0.829 – 1.03 0.153 362 3614 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 0.859 0.696 – 1.06 0.159 98 974 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.06 0.876 – 1.28 0.549 113 1141 exclusion phecode
590 Pyelonephritis Genitourinary 0.97 0.917 – 1.03 0.298 1306 13151 exclusion phecode
591 Urinary tract infection Genitourinary 1.01 0.988 – 1.03 0.465 11863 121851 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.03 0.99 – 1.07 0.146 2872 29228 exclusion phecode
592.1 Cystitis Genitourinary 1.03 0.993 – 1.07 0.113 2815 28602 exclusion phecode
592.11 Acute cystitis Genitourinary 1.06 0.887 – 1.26 0.528 132 1343 exclusion phecode
592.12 Chronic cystitis Genitourinary 1.05 0.983 – 1.13 0.136 865 8779 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 0.999 0.876 – 1.14 0.99 246 2470 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.965 0.816 – 1.14 0.676 156 1634 exclusion phecode
593 Hematuria Genitourinary 1.02 1 – 1.04 0.0202 15228 156911 exclusion phecode
594 Urinary calculus Genitourinary 1.01 0.98 – 1.03 0.64 6131 62275 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.02 0.981 – 1.06 0.355 3064 31042 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.07 0.987 – 1.15 0.101 691 7475 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.01 0.971 – 1.06 0.558 2312 23442 exclusion phecode
594.8 Renal colic Genitourinary 0.967 0.923 – 1.01 0.15 2002 20029 exclusion phecode
595 Hydronephrosis Genitourinary 0.994 0.946 – 1.04 0.793 1764 18937 exclusion phecode
596 Other disorders of bladder Genitourinary 1.03 1.01 – 1.05 0.0079 9041 95249 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.04 0.99 – 1.09 0.114 1710 18943 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1.02 0.971 – 1.08 0.398 1598 16305 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.03 0.993 – 1.06 0.115 3578 38376 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.03 0.99 – 1.07 0.149 3013 32411 exclusion phecode
597.2 Urinary complications NEC Genitourinary 0.782 0.612 – 1 0.05 71 765 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.06 1.02 – 1.09 0.0033 3254 34341 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.07 0.951 – 1.21 0.26 289 2973 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.03 1.02 – 1.05 3.9e-05 17368 181687 exclusion phecode
599.1 Urinary obstruction Genitourinary 1.07 0.902 – 1.26 0.452 155 1628 exclusion phecode
599.2 Retention of urine Genitourinary 1.03 0.998 – 1.05 0.0674 6021 65120 exclusion phecode
599.3 Dysuria Genitourinary 0.998 0.939 – 1.06 0.942 1146 11771 exclusion phecode
599.4 Urinary incontinence Genitourinary 1.03 1.01 – 1.06 0.0026 8456 87067 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.02 0.99 – 1.06 0.165 3786 39316 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.22 0.993 – 1.49 0.0583 100 1034 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.06 0.818 – 1.36 0.675 57 613 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1.03 0.977 – 1.08 0.3 1767 18685 exclusion phecode
600 Hyperplasia of prostate Genitourinary 1.07 1.05 – 1.09 2.41e-10 10039 87892 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 1.06 1.01 – 1.11 0.0156 1799 20818 exclusion phecode
601.1 Prostatitis Genitourinary 1.08 1.02 – 1.14 0.0123 1314 15644 exclusion phecode
601.11 Acute prostatitis Genitourinary 1.08 0.935 – 1.25 0.293 191 2358 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1.07 0.988 – 1.15 0.098 747 9089 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 1.04 0.798 – 1.35 0.775 58 588 exclusion phecode
601.4 Balanoposthitis Genitourinary 1.02 0.897 – 1.15 0.788 269 2864 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.03 0.914 – 1.16 0.648 284 3019 exclusion phecode
602 Other disorders of prostate Genitourinary 1.15 1.08 – 1.22 1.4e-05 1095 13408 exclusion phecode
603 Other disorders of testis Genitourinary 0.998 0.954 – 1.04 0.938 2051 20864 exclusion phecode
603.1 Hydrocele Genitourinary 1 0.947 – 1.06 0.93 1280 12954 exclusion phecode
604 Disorders of penis Genitourinary 0.978 0.943 – 1.01 0.238 3101 31826 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.976 0.937 – 1.02 0.241 2574 26388 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.979 0.852 – 1.13 0.765 207 2713 exclusion phecode
608 Other disorders of male genital organs Genitourinary 0.966 0.928 – 1 0.0849 2660 27447 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.09 0.937 – 1.27 0.259 177 2060 exclusion phecode
609.1 Infertility, male Genitourinary 0.919 0.712 – 1.19 0.515 63 630 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 1.17 0.982 – 1.4 0.0792 132 1629 exclusion phecode
610 Benign mammary dysplasias Genitourinary 1.01 0.966 – 1.05 0.764 2482 24809 exclusion phecode
610.1 Cystic mastopathy Genitourinary 1 0.939 – 1.07 0.906 925 9250 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1 0.889 – 1.13 0.969 306 3057 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 1.01 0.894 – 1.14 0.904 302 3018 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.994 0.941 – 1.05 0.845 1388 13865 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.07 0.99 – 1.16 0.087 696 6954 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.97 0.921 – 1.02 0.259 1572 15720 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.893 0.68 – 1.17 0.414 57 569 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.971 0.921 – 1.02 0.272 1520 15202 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.987 0.922 – 1.06 0.718 874 8820 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.996 0.929 – 1.07 0.916 836 8437 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 1.04 0.827 – 1.32 0.713 72 719 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 1.02 0.973 – 1.08 0.367 1649 16506 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 0.998 0.925 – 1.08 0.96 720 7204 exclusion phecode
613.5 Mastodynia Genitourinary 0.936 0.737 – 1.19 0.583 77 765 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 1.03 0.954 – 1.11 0.441 701 7012 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1.08 0.965 – 1.21 0.18 326 3276 exclusion phecode
613.9 Breast disorder NOS Genitourinary 0.974 0.846 – 1.12 0.718 207 2069 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1 0.975 – 1.03 0.908 5711 57118 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.01 0.975 – 1.06 0.474 2538 25363 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.977 0.91 – 1.05 0.524 830 8308 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.847 0.654 – 1.1 0.21 61 608 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.927 0.839 – 1.03 0.141 422 4221 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.01 0.905 – 1.12 0.877 351 3510 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1 0.888 – 1.13 0.998 277 2775 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.989 0.95 – 1.03 0.599 2601 26023 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.985 0.931 – 1.04 0.589 1318 13189 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.939 0.851 – 1.04 0.215 428 4273 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.02 0.949 – 1.1 0.564 755 7574 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.946 0.835 – 1.07 0.381 274 2737 exclusion phecode
615 Endometriosis Genitourinary 1 0.969 – 1.03 0.94 4029 40284 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 0.934 0.831 – 1.05 0.252 304 3037 exclusion phecode
618 Genital prolapse Genitourinary 1.02 1 – 1.04 0.0248 11689 116878 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 1.01 0.982 – 1.03 0.615 7392 73940 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.04 1.01 – 1.07 0.00892 5393 53918 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.1 1.01 – 1.21 0.035 512 5125 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.02 0.944 – 1.1 0.604 680 6794 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1.01 0.99 – 1.03 0.281 8726 87297 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.07 0.989 – 1.15 0.0917 729 7284 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 1 0.968 – 1.04 0.879 3324 33273 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1 0.966 – 1.04 0.824 2860 28608 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.03 0.983 – 1.08 0.205 1768 17669 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.04 0.985 – 1.1 0.15 1350 13489 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1.22 0.96 – 1.55 0.104 72 720 exclusion phecode
621 Endometrial hyperplasia Genitourinary 1.04 0.976 – 1.1 0.24 1129 11294 exclusion phecode
622 Polyp of female genital organs Genitourinary 1.03 1.01 – 1.05 0.00198 10480 104803 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 1.05 1.02 – 1.07 6.14e-05 7857 78601 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 0.988 0.954 – 1.02 0.517 3442 34387 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 0.972 0.918 – 1.03 0.342 1268 12684 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.947 0.88 – 1.02 0.139 797 7961 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.93 0.813 – 1.06 0.285 237 2365 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 0.988 0.898 – 1.09 0.813 440 4398 exclusion phecode
624.9 stress incontinence, female Genitourinary 1.01 0.982 – 1.04 0.547 5865 58634 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.976 0.939 – 1.01 0.206 2876 28740 exclusion phecode
625.1 Dyspareunia Genitourinary 0.962 0.906 – 1.02 0.199 1188 11891 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1 0.984 – 1.02 0.928 16168 115018 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1 0.986 – 1.02 0.735 14110 109918 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.863 0.707 – 1.05 0.147 109 1099 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1.01 0.988 – 1.03 0.425 9727 91749 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 1.02 0.977 – 1.07 0.341 1985 19829 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.99 0.958 – 1.02 0.556 3804 38021 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.98 0.933 – 1.03 0.409 1778 17767 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 1.03 0.872 – 1.2 0.761 159 1587 exclusion phecode
626.8 Infertility, female Genitourinary 0.989 0.936 – 1.05 0.711 1362 13613 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 1 0.984 – 1.02 0.714 10392 103948 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 1 0.981 – 1.02 0.849 9042 90439 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.975 0.84 – 1.13 0.734 183 1826 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.983 0.924 – 1.05 0.584 1111 11115 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1.01 0.895 – 1.13 0.911 310 3097 exclusion phecode
628 Ovarian cyst Genitourinary 1.02 0.99 – 1.05 0.193 4747 47482 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1 0.976 – 1.03 0.759 5218 36422 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.02 0.959 – 1.08 0.545 1136 11300 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.05 0.938 – 1.17 0.405 331 3305 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.01 0.961 – 1.06 0.767 1974 17372 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.02 0.947 – 1.09 0.646 866 8614 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1 0.948 – 1.06 0.879 1270 12306 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.04 0.997 – 1.09 0.069 2347 19972 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 1.03 0.944 – 1.12 0.537 617 6144 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.01 0.951 – 1.08 0.707 1082 10766 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 0.957 0.748 – 1.23 0.728 70 700 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.01 0.947 – 1.07 0.836 1110 11074 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.973 0.868 – 1.09 0.634 307 3058 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.05 0.917 – 1.21 0.466 215 2149 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.963 0.819 – 1.13 0.645 153 1525 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.06 1 – 1.13 0.0345 1250 12450 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.01 0.968 – 1.06 0.622 2228 20847 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.06 0.83 – 1.35 0.647 68 679 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.03 0.907 – 1.16 0.678 275 2748 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.967 0.801 – 1.17 0.726 113 1129 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.01 0.869 – 1.17 0.927 193 1922 exclusion phecode
650 Normal delivery Pregnancy Complications 1.04 0.996 – 1.09 0.0698 1922 18973 exclusion phecode
651 Multiple gestation Pregnancy Complications 1.08 0.97 – 1.21 0.153 346 3454 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.995 0.946 – 1.05 0.829 1716 16521 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.01 0.954 – 1.07 0.775 1401 13649 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.02 0.809 – 1.28 0.874 74 739 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.987 0.956 – 1.02 0.437 4306 29454 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.02 0.845 – 1.23 0.828 109 1078 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.99 0.948 – 1.03 0.659 2265 18397 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 1.04 0.952 – 1.14 0.376 532 5316 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.999 0.97 – 1.03 0.946 5313 29472 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.969 0.93 – 1.01 0.136 2552 21174 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.03 0.875 – 1.21 0.735 164 1628 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.972 0.855 – 1.1 0.659 262 2605 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.878 0.675 – 1.14 0.33 63 624 exclusion phecode
679 Complications of in utero procedures Dermatologic 0.981 0.738 – 1.3 0.894 53 530 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.01 0.99 – 1.04 0.257 7030 70659 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.993 0.91 – 1.08 0.875 553 5533 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.934 0.851 – 1.02 0.148 515 5125 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.01 0.986 – 1.04 0.334 5349 53770 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.02 0.991 – 1.05 0.189 5355 53825 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.02 0.988 – 1.04 0.273 5313 53396 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1 0.918 – 1.09 0.994 574 5895 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.01 0.957 – 1.07 0.643 1310 13157 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1 0.957 – 1.04 0.996 2242 22535 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.03 0.945 – 1.12 0.51 577 5761 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.09 0.98 – 1.21 0.113 356 3567 exclusion phecode
687 Symptoms affecting skin Dermatologic 0.963 0.881 – 1.05 0.402 537 5409 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.03 0.983 – 1.08 0.224 2096 21110 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 0.976 0.861 – 1.11 0.7 278 2795 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.976 0.796 – 1.2 0.819 103 1054 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 0.994 0.957 – 1.03 0.765 2839 28454 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.994 0.968 – 1.02 0.684 5632 56496 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.887 0.691 – 1.14 0.349 71 696 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 1.01 0.763 – 1.33 0.964 53 517 exclusion phecode
691 Congenital anomalies of skin Dermatologic 1.17 0.969 – 1.41 0.103 119 1181 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.982 0.919 – 1.05 0.593 972 9691 exclusion phecode
694.1 Vitiligo Dermatologic 1.11 0.859 – 1.44 0.418 59 590 exclusion phecode
694.2 Other dyschromia Dermatologic 0.947 0.879 – 1.02 0.146 771 7690 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.11 0.92 – 1.33 0.278 115 1152 exclusion phecode
695 Erythematous conditions Dermatologic 0.957 0.917 – 0.998 0.0424 2339 23472 exclusion phecode
695.1 Toxic erythema Dermatologic 0.919 0.76 – 1.11 0.384 109 1071 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.04 0.873 – 1.24 0.669 136 1339 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 1.02 0.78 – 1.33 0.893 57 554 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.08 0.855 – 1.37 0.505 72 710 exclusion phecode
695.3 Rosacea Dermatologic 1.01 0.903 – 1.14 0.803 299 3014 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 0.958 0.864 – 1.06 0.407 407 4086 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.975 0.815 – 1.17 0.777 130 1288 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 0.955 0.853 – 1.07 0.426 336 3387 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 0.982 0.911 – 1.06 0.629 764 7677 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 0.999 0.874 – 1.14 0.987 232 2320 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.929 0.735 – 1.17 0.537 76 755 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 0.886 0.804 – 0.976 0.0144 454 4579 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.966 0.925 – 1.01 0.125 2202 22083 exclusion phecode
696.4 Psoriasis Dermatologic 0.963 0.921 – 1.01 0.0982 2151 21566 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.944 0.897 – 0.993 0.0268 1641 16463 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.998 0.923 – 1.08 0.952 696 6946 exclusion phecode
697 Sarcoidosis Dermatologic 1.01 0.925 – 1.11 0.792 529 5297 exclusion phecode
698 Pruritus and related conditions Dermatologic 1.04 0.969 – 1.13 0.251 767 7696 exclusion phecode
700 Corns and callosities Dermatologic 0.926 0.821 – 1.05 0.215 286 2878 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.988 0.959 – 1.02 0.443 4582 45987 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.974 0.788 – 1.2 0.804 87 841 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.01 0.972 – 1.06 0.524 2311 23153 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.952 0.73 – 1.24 0.717 60 607 exclusion phecode
701.4 Keloid scar Dermatologic 1.05 0.917 – 1.21 0.459 213 2143 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 0.887 0.804 – 0.978 0.0159 446 4500 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.1 0.902 – 1.34 0.353 101 996 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.01 0.986 – 1.04 0.312 5341 53450 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.987 0.947 – 1.03 0.536 2517 25255 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 1.04 1 – 1.08 0.0323 3019 30155 exclusion phecode
703 Diseases of nail, NOS Dermatologic 0.942 0.845 – 1.05 0.284 346 3473 exclusion phecode
703.1 Ingrowing nail Dermatologic 1.01 0.944 – 1.08 0.794 945 9515 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 1.01 0.985 – 1.04 0.371 5171 51901 exclusion phecode
704.1 Alopecia Dermatologic 1.01 0.842 – 1.22 0.879 125 1263 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.832 0.654 – 1.06 0.134 75 753 exclusion phecode
705 Disorders of sweat glands Dermatologic 1 0.871 – 1.15 0.997 228 2267 exclusion phecode
705.3 Hidradenitis Dermatologic 1.03 0.883 – 1.19 0.74 186 1855 exclusion phecode
705.8 Hyperhidrosis Dermatologic 0.986 0.905 – 1.07 0.739 578 5786 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1.02 0.993 – 1.04 0.165 8155 81890 exclusion phecode
706.1 Acne Dermatologic 1.08 0.854 – 1.36 0.522 74 768 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1.02 0.999 – 1.04 0.0669 8615 86465 exclusion phecode
707 Chronic ulcer of skin Dermatologic 0.983 0.938 – 1.03 0.469 1903 19086 exclusion phecode
707.1 Decubitus ulcer Dermatologic 0.975 0.91 – 1.05 0.478 876 8834 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.98 0.946 – 1.02 0.265 3381 33798 exclusion phecode
709.2 Sicca syndrome Dermatologic 0.978 0.893 – 1.07 0.631 508 5055 exclusion phecode
709.3 Systemic sclerosis Dermatologic 1.03 0.882 – 1.19 0.735 175 1744 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.915 0.714 – 1.17 0.48 65 648 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.991 0.952 – 1.03 0.646 2663 26661 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.979 0.899 – 1.07 0.62 584 5898 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 0.974 0.892 – 1.06 0.562 539 5449 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.917 0.791 – 1.06 0.249 188 1907 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.996 0.896 – 1.11 0.943 386 3903 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 1.02 0.921 – 1.13 0.731 411 4148 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.01 0.9 – 1.13 0.887 321 3225 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 0.894 0.71 – 1.13 0.342 78 786 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.986 0.828 – 1.17 0.876 142 1470 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.05 0.802 – 1.36 0.743 61 653 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.06 1.03 – 1.09 0.000269 4765 47690 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.06 1.03 – 1.1 0.000151 4315 43154 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.02 0.97 – 1.07 0.434 1607 16271 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.1 0.913 – 1.34 0.308 111 1116 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.986 0.905 – 1.07 0.738 590 6029 exclusion phecode
716 Other arthropathies Musculoskeletal 0.993 0.982 – 1 0.212 36631 261143 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.989 0.955 – 1.02 0.532 3426 34569 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.988 0.972 – 1 0.163 15181 152337 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 0.993 0.982 – 1 0.201 35135 258088 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.04 0.98 – 1.11 0.191 1114 11260 exclusion phecode
720 Spinal stenosis Musculoskeletal 1.01 0.971 – 1.04 0.771 3616 36332 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 0.983 0.961 – 1.01 0.165 7656 77053 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.981 0.952 – 1.01 0.189 4943 49644 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.97 0.836 – 1.13 0.689 185 1861 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 0.976 0.873 – 1.09 0.666 333 3458 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 0.985 0.963 – 1.01 0.167 8815 88543 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.983 0.897 – 1.08 0.708 502 5029 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.983 0.945 – 1.02 0.384 2787 27908 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.28 0.998 – 1.64 0.0516 67 665 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.01 0.975 – 1.04 0.695 4324 43490 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 0.99 0.903 – 1.09 0.836 505 5080 exclusion phecode
723.1 Torticollis Musculoskeletal 1.08 0.882 – 1.32 0.46 105 1054 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 0.995 0.95 – 1.04 0.825 2007 20204 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 0.989 0.892 – 1.1 0.84 399 4005 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.992 0.895 – 1.1 0.878 402 4035 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 0.912 0.696 – 1.19 0.504 62 621 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 0.995 0.945 – 1.05 0.849 1574 15845 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.993 0.976 – 1.01 0.411 14413 144292 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.991 0.97 – 1.01 0.384 9425 94329 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.995 0.892 – 1.11 0.936 330 3308 exclusion phecode
726.3 Bursitis Musculoskeletal 0.991 0.923 – 1.06 0.81 829 8363 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1 0.977 – 1.02 0.96 7225 72335 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.999 0.96 – 1.04 0.941 2694 27008 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.904 0.74 – 1.1 0.321 99 999 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.01 0.973 – 1.05 0.612 3078 30746 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.948 0.871 – 1.03 0.21 575 5736 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.11 0.997 – 1.24 0.0563 344 3451 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.945 0.795 – 1.12 0.525 140 1398 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.989 0.955 – 1.02 0.538 3564 35543 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.02 0.917 – 1.13 0.764 407 4066 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.994 0.961 – 1.03 0.748 3689 36802 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.992 0.957 – 1.03 0.659 3370 33591 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 0.98 0.954 – 1.01 0.136 5886 59345 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.982 0.921 – 1.05 0.58 1000 10027 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.749 0.608 – 0.923 0.00672 101 992 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.944 0.832 – 1.07 0.37 268 2733 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.936 0.822 – 1.06 0.314 254 2584 exclusion phecode
732 Osteochondropathies Musculoskeletal 1.12 1.01 – 1.23 0.0263 456 4616 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.12 0.971 – 1.3 0.12 200 2045 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.2 0.904 – 1.58 0.211 56 566 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.977 0.931 – 1.03 0.359 1757 17637 exclusion phecode
733.2 Cyst of bone Musculoskeletal 0.881 0.783 – 0.991 0.0351 307 3082 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.935 0.857 – 1.02 0.134 527 5311 exclusion phecode
733.6 Costochondritis Musculoskeletal 1.03 0.856 – 1.23 0.785 124 1260 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.01 0.948 – 1.07 0.848 1216 12136 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.1 0.92 – 1.32 0.287 118 1195 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1.01 0.987 – 1.03 0.449 9546 95493 exclusion phecode
735.1 Flat foot Musculoskeletal 0.91 0.78 – 1.06 0.229 186 1891 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 0.988 0.96 – 1.02 0.402 5034 50313 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1 0.955 – 1.05 0.987 1919 19197 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.955 0.906 – 1.01 0.0868 1537 15363 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.01 0.989 – 1.04 0.266 6618 66212 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1.04 0.985 – 1.09 0.164 1604 15973 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.04 0.916 – 1.18 0.54 246 2439 exclusion phecode
737 Curvature of spine Musculoskeletal 1.04 0.981 – 1.11 0.181 1113 11185 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.05 0.983 – 1.11 0.157 1046 10527 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.01 0.966 – 1.06 0.595 1877 18821 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.02 0.97 – 1.08 0.405 1494 14960 exclusion phecode
739 Contracture of joint Musculoskeletal 1.04 0.944 – 1.14 0.457 484 4812 exclusion phecode
740 Osteoarthrosis Musculoskeletal 0.994 0.982 – 1.01 0.388 27102 227372 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.989 0.973 – 1 0.16 17055 166089 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.984 0.963 – 1.01 0.155 8781 87904 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.961 0.858 – 1.08 0.495 336 3402 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.943 0.865 – 1.03 0.188 585 5867 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.997 0.978 – 1.02 0.755 11968 120664 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.973 0.94 – 1.01 0.124 3484 35051 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.974 0.797 – 1.19 0.795 101 1001 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 0.967 0.889 – 1.05 0.435 604 6068 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 1.03 0.875 – 1.21 0.718 151 1507 exclusion phecode
741.4 Joint effusions Musculoskeletal 0.966 0.914 – 1.02 0.225 1379 13911 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 0.886 0.728 – 1.08 0.231 107 1080 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 1.04 0.779 – 1.38 0.804 53 528 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.02 0.985 – 1.06 0.234 2802 28091 exclusion phecode
742.1 Loose body in joint Musculoskeletal 1.03 0.916 – 1.15 0.659 321 3267 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.949 0.771 – 1.17 0.62 94 959 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.06 0.963 – 1.16 0.251 493 4943 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 1.02 0.978 – 1.07 0.301 1972 19694 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1 0.977 – 1.03 0.928 7361 74961 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.01 0.982 – 1.03 0.575 6222 63493 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1 0.975 – 1.03 0.89 5492 55201 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1.09 0.987 – 1.2 0.0877 422 5152 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 0.96 0.874 – 1.05 0.4 498 5083 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1 0.93 – 1.07 0.991 806 8051 exclusion phecode
745 Pain in joint Musculoskeletal 0.98 0.958 – 1 0.0881 7835 78567 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.02 0.979 – 1.06 0.375 2745 27314 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.03 0.986 – 1.07 0.206 2573 25615 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1.01 0.923 – 1.09 0.906 578 5759 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.04 0.912 – 1.19 0.553 233 2310 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.04 0.991 – 1.09 0.108 1771 17594 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.887 0.757 – 1.04 0.139 166 1649 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.05 0.936 – 1.19 0.382 298 2989 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.976 0.902 – 1.06 0.539 670 6737 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.971 0.865 – 1.09 0.622 318 3178 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.04 0.893 – 1.2 0.639 185 1854 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.956 0.859 – 1.07 0.417 349 3528 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.04 0.906 – 1.18 0.611 221 2218 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.872 0.721 – 1.05 0.157 114 1165 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.03 0.973 – 1.08 0.352 1484 14996 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.01 0.936 – 1.1 0.755 680 6849 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.05 0.951 – 1.15 0.348 455 4546 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.869 0.754 – 1 0.0526 209 2152 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.05 0.98 – 1.13 0.162 807 8192 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 1.11 1 – 1.23 0.0415 409 4150 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.97 0.865 – 1.09 0.599 324 3260 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.02 0.914 – 1.15 0.691 323 3274 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 0.97 0.854 – 1.1 0.646 250 2537 exclusion phecode
752.11 Spina bifida Congenital Anomalies 1.05 0.914 – 1.21 0.485 206 2090 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.16 0.915 – 1.47 0.22 77 766 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.05 0.875 – 1.27 0.588 125 1258 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.1 0.868 – 1.39 0.431 75 752 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.04 0.854 – 1.27 0.701 109 1090 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1 0.905 – 1.1 0.998 420 4226 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.04 0.904 – 1.2 0.574 207 2058 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.92 0.784 – 1.08 0.311 160 1611 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.966 0.795 – 1.17 0.731 106 1067 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.09 1 – 1.18 0.0499 575 5793 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.17 0.931 – 1.48 0.177 81 797 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.11 1.01 – 1.22 0.0392 425 4303 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.03 0.872 – 1.21 0.735 146 1683 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.05 0.81 – 1.35 0.731 60 819 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.05 0.916 – 1.21 0.464 213 2131 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.17 0.943 – 1.44 0.157 94 945 exclusion phecode
760 Back pain Symptoms 0.995 0.975 – 1.01 0.589 10907 109747 exclusion phecode
761 Cervicalgia Symptoms 0.978 0.931 – 1.03 0.371 1758 17638 exclusion phecode
764 Sciatica Symptoms 0.976 0.936 – 1.02 0.262 2337 23418 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.01 0.946 – 1.07 0.858 1149 11575 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 0.966 0.889 – 1.05 0.408 618 6212 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.02 0.949 – 1.09 0.621 851 8555 exclusion phecode
771.1 Swelling of limb Symptoms 0.977 0.948 – 1.01 0.142 4502 45459 exclusion phecode
772 Symptoms of the muscles Symptoms 1.01 0.93 – 1.09 0.862 650 6452 exclusion phecode
773 Pain in limb Symptoms 0.981 0.956 – 1.01 0.16 6089 61297 exclusion phecode
780 Hypothermia/Chills Symptoms 1.03 0.884 – 1.2 0.698 166 1685 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.984 0.938 – 1.03 0.508 1833 18388 exclusion phecode
782.3 Edema Symptoms 0.998 0.948 – 1.05 0.951 1586 16094 exclusion phecode
782.6 Pallor and flushing Symptoms 1.12 0.958 – 1.32 0.154 170 1711 exclusion phecode
783 Fever of unknown origin Symptoms 1.02 0.986 – 1.05 0.245 3775 38375 exclusion phecode
785 Abdominal pain Symptoms 0.994 0.984 – 1.01 0.304 39435 297189 exclusion phecode
788 Syncope and collapse Symptoms 1 0.979 – 1.02 0.939 8808 88746 exclusion phecode
789 Nausea and vomiting Symptoms 1 0.984 – 1.02 0.752 11335 114262 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.13 0.953 – 1.34 0.158 145 1465 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 0.931 0.738 – 1.17 0.549 83 831 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.06 1.03 – 1.09 1.81e-05 5369 61665 exclusion phecode
791 Gangrene Symptoms 0.988 0.904 – 1.08 0.791 536 5360 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.978 0.792 – 1.21 0.837 98 966 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.861 0.718 – 1.03 0.105 125 1310 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.02 0.929 – 1.11 0.734 539 5531 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.03 0.853 – 1.24 0.781 119 1189 exclusion phecode
797 Shock Symptoms 0.963 0.818 – 1.13 0.646 150 1507 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.02 0.837 – 1.24 0.864 98 983 exclusion phecode
798 Malaise and fatigue Symptoms 1.01 0.976 – 1.05 0.546 3320 33558 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 0.985 0.906 – 1.07 0.723 589 5864 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.02 0.993 – 1.04 0.156 6936 69335 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.05 1 – 1.1 0.0456 1787 17873 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.934 0.798 – 1.09 0.392 168 1659 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.989 0.946 – 1.03 0.629 2132 21268 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 1.02 0.951 – 1.1 0.524 744 7520 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.977 0.936 – 1.02 0.305 2175 21769 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 0.982 0.936 – 1.03 0.447 1806 18122 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.04 0.963 – 1.12 0.32 707 7055 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.991 0.969 – 1.01 0.419 8183 81926 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1 0.954 – 1.05 0.911 1659 16650 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.986 0.958 – 1.01 0.337 5172 51727 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.01 0.956 – 1.06 0.778 1482 14890 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.997 0.963 – 1.03 0.887 3312 32917 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.996 0.941 – 1.05 0.886 1317 13312 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 0.936 0.868 – 1.01 0.0847 755 7558 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.963 0.909 – 1.02 0.204 1265 12749 exclusion phecode
817 Concussion Injuries & Poisonings 1.01 0.885 – 1.15 0.894 241 2369 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.926 0.846 – 1.01 0.0999 503 5074 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.987 0.95 – 1.03 0.503 2898 29109 exclusion phecode
823 Torus fracture Injuries & Poisonings 0.992 0.943 – 1.04 0.76 1652 16477 exclusion phecode
830 Dislocation Injuries & Poisonings 1 0.959 – 1.05 0.875 2055 20551 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 1 0.987 – 1.02 0.681 14941 149725 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.975 0.891 – 1.07 0.586 513 5180 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.96 0.873 – 1.06 0.401 464 4637 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.984 0.957 – 1.01 0.284 5100 51670 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.982 0.837 – 1.15 0.824 156 1533 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.03 0.939 – 1.13 0.534 489 4888 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.973 0.927 – 1.02 0.264 1776 17656 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.05 0.985 – 1.12 0.135 1053 12113 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.996 0.96 – 1.03 0.851 3118 31097 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 0.965 0.931 – 1 0.0581 3208 32046 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.07 0.827 – 1.38 0.62 68 673 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1 0.966 – 1.04 0.975 3445 34379 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.24 1.09 – 1.4 0.000699 270 2668 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1.09 0.945 – 1.26 0.233 195 1917 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.987 0.95 – 1.03 0.519 2851 28499 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.03 0.896 – 1.18 0.689 215 2155 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 1.24 0.964 – 1.61 0.0933 68 665 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 0.986 0.955 – 1.02 0.41 3990 39858 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.13 0.903 – 1.41 0.289 89 885 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.2 1.03 – 1.41 0.0197 177 1749 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.04 0.946 – 1.15 0.411 459 4637 exclusion phecode
873 Broken tooth Injuries & Poisonings 0.976 0.853 – 1.12 0.727 224 2257 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 0.994 0.848 – 1.17 0.94 166 1668 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.04 0.882 – 1.23 0.638 155 1538 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1 0.947 – 1.06 0.92 1282 12891 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.01 0.981 – 1.05 0.425 4168 41885 exclusion phecode
916 Contusion Injuries & Poisonings 1.06 1 – 1.12 0.0466 1419 14247 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 1.05 0.902 – 1.22 0.532 179 1796 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.952 0.857 – 1.06 0.361 382 3814 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.979 0.859 – 1.12 0.751 246 2466 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.03 0.987 – 1.08 0.162 2063 20587 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.07 0.931 – 1.22 0.348 221 2199 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.931 0.761 – 1.14 0.489 101 1025 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.01 0.93 – 1.11 0.758 541 5417 exclusion phecode
947 Urticaria Injuries & Poisonings 0.987 0.888 – 1.1 0.811 365 3660 exclusion phecode
949 Allergies, other Injuries & Poisonings 0.938 0.846 – 1.04 0.22 391 3936 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.95 0.86 – 1.05 0.311 414 4147 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.02 0.902 – 1.16 0.711 261 2626 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.917 0.836 – 1.01 0.0679 478 4828 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 0.679 0.508 – 0.908 0.00902 53 541 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.963 0.755 – 1.23 0.765 73 725 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.991 0.976 – 1.01 0.275 17761 179018 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.99 0.974 – 1.01 0.252 15534 156663 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.04 0.942 – 1.16 0.416 411 4153 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1 0.936 – 1.08 0.915 864 8668 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.06 0.955 – 1.18 0.264 365 3657 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.04 0.932 – 1.16 0.484 358 3589 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.04 0.905 – 1.19 0.59 219 2210 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.01 0.888 – 1.14 0.911 262 2754 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.994 0.875 – 1.13 0.925 256 2693 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.02 0.99 – 1.04 0.222 5957 60181 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.959 0.902 – 1.02 0.183 1124 11320 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.02 0.925 – 1.12 0.731 469 4730 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.989 0.893 – 1.1 0.832 395 3959 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.1 1 – 1.2 0.0435 503 5063 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.989 0.908 – 1.08 0.803 570 5782 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.04 0.996 – 1.09 0.0746 1926 19356 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.06 0.91 – 1.22 0.476 188 1884 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1 0.877 – 1.14 0.999 267 2674 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.826 0.655 – 1.04 0.109 83 834 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 0.95 0.775 – 1.16 0.621 106 1066 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.2 0.977 – 1.47 0.0824 95 999 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.12 0.872 – 1.43 0.379 61 630 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.943 0.727 – 1.22 0.655 58 574 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.958 0.837 – 1.1 0.534 227 2313 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.02 0.943 – 1.11 0.608 682 6898 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.04 0.901 – 1.21 0.565 195 1979 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.07 0.826 – 1.38 0.614 61 606 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.05 0.851 – 1.29 0.67 104 1029 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 1.04 0.851 – 1.26 0.718 108 1117 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.31 1.05 – 1.63 0.0146 87 874 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.04 1 – 1.08 0.0441 2563 30511 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.01 0.975 – 1.05 0.513 2877 29569 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.01 0.975 – 1.05 0.513 2877 29569 exclusion phecode
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