Departments of Anesthesiology and Biostatistics | University of Michigan

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Cancer PRSweb

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Scores Thyroid cancer UK Biobank (UKB) PheWAS analysis

Thyroid cancer — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID prsweb-phecode193-gwas-catalog-r2019-05-03-x193-pt-ukb-20200608Legacy P&TP&TGWAS Catalog (2019-05-03)

Evaluation cohort: UK Biobank (UKB).

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73 rows visible 16 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.02 0.994 – 1.04 0.159 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.01 0.972 – 1.05 0.576 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.01 0.933 – 1.1 0.788 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 0.966 0.901 – 1.04 0.333 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.19 0.899 – 1.59 0.222 55 550 all phecode
010 Tuberculosis Infectious Diseases 0.92 0.784 – 1.08 0.305 166 1659 all phecode
038 Septicemia Infectious Diseases 0.996 0.965 – 1.03 0.795 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 0.978 0.912 – 1.05 0.528 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.05 0.96 – 1.15 0.274 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 0.987 0.969 – 1.01 0.184 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.01 0.976 – 1.05 0.501 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 1.01 0.96 – 1.06 0.7 1641 16433 all phecode
041.4 E. coli Infectious Diseases 0.981 0.943 – 1.02 0.329 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 0.984 0.889 – 1.09 0.751 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.18 0.956 – 1.45 0.124 95 949 all phecode
054 Herpes simplex Infectious Diseases 0.971 0.841 – 1.12 0.687 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 1.01 0.925 – 1.09 0.905 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 0.925 0.728 – 1.18 0.526 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 0.908 0.759 – 1.09 0.296 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.05 0.925 – 1.19 0.458 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.05 0.925 – 1.18 0.471 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 0.899 0.814 – 0.993 0.0353 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.92 0.777 – 1.09 0.331 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.991 0.822 – 1.19 0.92 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 0.955 0.895 – 1.02 0.168 1004 10036 all phecode
079 Viral infection Infectious Diseases 1.03 0.987 – 1.07 0.196 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 1.05 0.811 – 1.35 0.725 64 640 all phecode
080 Postoperative infection Infectious Diseases 0.998 0.968 – 1.03 0.888 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.03 0.989 – 1.07 0.153 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.793 0.617 – 1.02 0.0712 71 709 all phecode
1000 Burns Injuries & Poisonings 0.999 0.918 – 1.09 0.988 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 0.97 0.914 – 1.03 0.315 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 0.988 0.961 – 1.02 0.389 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.02 0.91 – 1.15 0.706 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 0.98 0.928 – 1.03 0.461 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 0.976 0.858 – 1.11 0.711 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 1.1 0.974 – 1.25 0.122 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.01 0.948 – 1.08 0.751 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 1.01 0.989 – 1.03 0.334 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 0.999 0.973 – 1.03 0.949 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.996 0.975 – 1.02 0.739 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 1.2 0.981 – 1.46 0.0774 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 0.953 0.849 – 1.07 0.41 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.951 0.738 – 1.22 0.697 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 0.999 0.968 – 1.03 0.967 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 0.989 0.973 – 1 0.172 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.941 0.832 – 1.06 0.337 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 0.956 0.844 – 1.08 0.479 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.858 0.675 – 1.09 0.213 74 756 all phecode
110.12 Althete's foot Infectious Diseases 1.02 0.859 – 1.21 0.823 141 1410 all phecode
112 Candidiasis Infectious Diseases 1.01 0.966 – 1.06 0.659 2126 21275 all phecode
117 Mycoses Infectious Diseases 1.01 0.888 – 1.14 0.929 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 1.05 0.895 – 1.22 0.566 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 1.3 1.04 – 1.62 0.0189 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 1.06 0.834 – 1.35 0.631 69 689 all phecode
134 Helminthiases Infectious Diseases 1.11 0.924 – 1.34 0.263 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.18 0.966 – 1.44 0.106 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.12 0.972 – 1.29 0.117 205 2050 all phecode
145 Cancer of mouth Neoplasms 0.979 0.902 – 1.06 0.606 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 0.959 0.853 – 1.08 0.484 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.05 0.867 – 1.28 0.602 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 0.93 0.705 – 1.23 0.607 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.03 0.947 – 1.11 0.518 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 1.07 0.943 – 1.22 0.288 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 1.02 0.897 – 1.15 0.794 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 1.12 0.855 – 1.48 0.403 57 570 all phecode
150 Cancer of esophagus Neoplasms 1.03 0.953 – 1.1 0.499 762 7630 all phecode
151 Cancer of stomach Neoplasms 0.986 0.904 – 1.07 0.742 569 5696 all phecode
153 Colorectal cancer Neoplasms 1 0.975 – 1.04 0.76 4580 45799 all phecode
153.2 Colon cancer Neoplasms 1 0.968 – 1.04 0.813 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.02 0.972 – 1.06 0.474 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.07 0.968 – 1.19 0.183 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.03 0.88 – 1.21 0.703 158 1580 all phecode
157 Pancreatic cancer Neoplasms 1.01 0.929 – 1.09 0.865 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.02 0.956 – 1.08 0.581 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.996 0.969 – 1.02 0.759 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.09 0.935 – 1.26 0.28 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.918 0.795 – 1.06 0.249 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.909 0.783 – 1.06 0.212 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 1.01 0.782 – 1.3 0.939 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 0.977 0.94 – 1.02 0.241 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 0.987 0.945 – 1.03 0.551 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 1.02 0.922 – 1.12 0.746 437 4364 all phecode
170.1 Bone cancer Neoplasms 1.18 0.986 – 1.4 0.0706 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 0.965 0.862 – 1.08 0.536 331 3303 all phecode
172 Skin cancer Neoplasms 0.998 0.981 – 1.02 0.834 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.999 0.96 – 1.04 0.968 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 1 0.962 – 1.04 0.956 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.996 0.977 – 1.02 0.721 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 0.971 0.896 – 1.05 0.469 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.931 0.799 – 1.09 0.363 181 1818 all phecode
174 Breast cancer Neoplasms 1.01 0.992 – 1.03 0.276 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 1.01 0.991 – 1.03 0.297 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.01 0.993 – 1.03 0.209 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.07 0.888 – 1.3 0.469 115 1148 all phecode
175 Acquired absence of breast Neoplasms 1.04 0.998 – 1.08 0.0616 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 0.995 0.952 – 1.04 0.813 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 0.986 0.872 – 1.12 0.827 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.996 0.952 – 1.04 0.863 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 1.04 0.982 – 1.1 0.18 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 0.988 0.935 – 1.04 0.668 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.02 0.954 – 1.09 0.586 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.01 0.947 – 1.08 0.712 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.896 0.797 – 1.01 0.0684 305 3049 all phecode
185 Cancer of prostate Neoplasms 1 0.973 – 1.03 0.989 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 1.05 0.949 – 1.15 0.366 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.2 0.938 – 1.52 0.15 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 1.01 0.897 – 1.14 0.848 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.11 0.918 – 1.34 0.287 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.02 0.987 – 1.05 0.258 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.993 0.932 – 1.06 0.819 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.984 0.922 – 1.05 0.633 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.23 0.954 – 1.58 0.111 66 660 all phecode
189.2 Cancer of bladder Neoplasms 1.02 0.981 – 1.07 0.301 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.02 0.974 – 1.06 0.43 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1 0.849 – 1.19 0.954 144 1439 all phecode
190 Cancer of eye Neoplasms 0.938 0.805 – 1.09 0.412 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.02 0.945 – 1.1 0.604 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1.01 0.924 – 1.1 0.877 566 5650 all phecode
191.11 Cancer of brain Neoplasms 1.01 0.925 – 1.11 0.809 525 5240 all phecode
193 Thyroid cancer Neoplasms 1.67 1.5 – 1.86 1.97e-21 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 1.02 0.826 – 1.26 0.847 95 949 all phecode
195 Cancer, suspected or other Neoplasms 1 0.988 – 1.02 0.645 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 1 0.988 – 1.02 0.605 16267 159497 all phecode
197 Chemotherapy Neoplasms 1.02 1.01 – 1.04 0.00315 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 1.02 0.999 – 1.04 0.0601 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.03 1 – 1.06 0.0402 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.06 1.02 – 1.11 0.00548 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.02 0.965 – 1.07 0.527 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.01 0.974 – 1.05 0.519 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1 0.933 – 1.07 0.977 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.02 0.979 – 1.07 0.317 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.892 0.766 – 1.04 0.137 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.02 0.97 – 1.08 0.38 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 1.17 0.957 – 1.44 0.124 95 950 all phecode
200 Myeloproliferative disease Neoplasms 1.04 0.979 – 1.11 0.187 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 1.09 0.986 – 1.21 0.092 387 3867 all phecode
201 Hodgkin's disease Neoplasms 1.05 0.924 – 1.19 0.476 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.979 0.938 – 1.02 0.345 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.965 0.92 – 1.01 0.15 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 1.1 0.991 – 1.22 0.0725 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 0.962 0.884 – 1.05 0.376 581 5824 all phecode
204 Leukemia Neoplasms 1 0.955 – 1.06 0.855 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 1.03 0.944 – 1.12 0.537 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.938 0.711 – 1.24 0.653 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.04 0.95 – 1.14 0.391 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 1.03 0.939 – 1.13 0.51 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 1.05 0.944 – 1.18 0.353 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.05 0.884 – 1.24 0.591 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 0.927 0.849 – 1.01 0.0938 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 1.01 0.991 – 1.02 0.441 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.901 0.842 – 0.963 0.00213 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.03 1 – 1.06 0.0266 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.05 0.94 – 1.17 0.394 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.07 0.955 – 1.2 0.241 318 3187 all phecode
214 Lipoma Neoplasms 0.98 0.955 – 1.01 0.132 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.978 0.949 – 1.01 0.16 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.969 0.91 – 1.03 0.327 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 0.992 0.969 – 1.02 0.491 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.06 0.979 – 1.15 0.147 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.09 1.01 – 1.19 0.0358 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 1 0.98 – 1.02 0.956 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 1 0.985 – 1.03 0.636 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.945 0.848 – 1.05 0.301 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 0.911 0.862 – 0.963 0.000929 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.04 0.904 – 1.19 0.592 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.847 0.72 – 0.998 0.0466 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.01 0.871 – 1.18 0.85 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 1.01 0.848 – 1.21 0.884 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.11 0.874 – 1.42 0.381 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.03 0.961 – 1.11 0.386 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.04 0.965 – 1.12 0.313 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.915 0.701 – 1.19 0.513 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.21 1.08 – 1.37 0.00166 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.03 0.959 – 1.1 0.428 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.941 0.809 – 1.09 0.427 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.07 0.96 – 1.19 0.226 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.04 0.929 – 1.17 0.486 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.958 0.91 – 1.01 0.103 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.01 0.966 – 1.05 0.716 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.05 0.963 – 1.13 0.291 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.982 0.923 – 1.04 0.56 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.16 1.06 – 1.27 0.00154 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.881 0.813 – 0.955 0.00219 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.996 0.95 – 1.04 0.872 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 0.967 0.878 – 1.06 0.486 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.13 0.92 – 1.39 0.244 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 1 0.843 – 1.2 0.965 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 0.901 0.885 – 0.917 3.29e-32 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.06 0.999 – 1.13 0.0525 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.745 0.601 – 0.924 0.0073 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.891 0.875 – 0.907 2.64e-37 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 1.02 0.906 – 1.15 0.727 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.04 0.906 – 1.19 0.584 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.06 0.92 – 1.22 0.428 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 0.902 0.813 – 0.999 0.0487 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.01 0.999 – 1.03 0.0773 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.05 1.01 – 1.09 0.0231 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.954 0.837 – 1.09 0.476 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.13 0.89 – 1.43 0.321 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.02 0.927 – 1.12 0.703 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.03 0.88 – 1.21 0.689 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.01 0.999 – 1.03 0.0738 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.917 0.741 – 1.13 0.421 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.99 0.856 – 1.15 0.898 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.986 0.923 – 1.05 0.684 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.09 0.997 – 1.19 0.0589 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.07 0.991 – 1.16 0.0845 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.06 0.934 – 1.2 0.376 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.09 0.986 – 1.2 0.0932 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.991 0.833 – 1.18 0.921 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.07 0.966 – 1.2 0.186 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.01 0.951 – 1.07 0.806 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.04 0.973 – 1.11 0.253 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.02 0.952 – 1.1 0.555 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.01 0.942 – 1.09 0.709 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.09 0.917 – 1.29 0.338 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.938 0.866 – 1.01 0.11 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.07 0.918 – 1.24 0.392 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.09 0.882 – 1.34 0.438 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.837 0.737 – 0.952 0.00649 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.79 0.634 – 0.985 0.0361 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.02 0.872 – 1.19 0.811 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.997 0.919 – 1.08 0.938 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.05 0.901 – 1.22 0.543 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.04 0.853 – 1.28 0.673 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.06 0.842 – 1.32 0.641 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.934 0.838 – 1.04 0.216 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.93 0.834 – 1.04 0.191 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 0.876 0.762 – 1.01 0.0621 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.863 0.744 – 1 0.0537 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 0.86 0.728 – 1.02 0.0769 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.859 0.724 – 1.02 0.0794 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.06 0.868 – 1.29 0.568 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 0.805 0.676 – 0.958 0.0148 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.976 0.848 – 1.12 0.737 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 1.04 0.785 – 1.37 0.799 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 0.971 0.904 – 1.04 0.42 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.04 0.981 – 1.1 0.184 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.04 0.968 – 1.12 0.269 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.05 0.957 – 1.16 0.288 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.1 0.877 – 1.39 0.4 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.02 0.89 – 1.16 0.814 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 1.01 0.903 – 1.13 0.872 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.906 0.805 – 1.02 0.101 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.944 0.832 – 1.07 0.376 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.04 0.897 – 1.2 0.622 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.06 0.873 – 1.28 0.578 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.738 0.569 – 0.959 0.0228 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.26 1.07 – 1.49 0.00577 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.33 1.12 – 1.59 0.00159 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1 0.993 – 1.02 0.469 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1 0.993 – 1.02 0.464 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1 0.991 – 1.01 0.647 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.688 0.518 – 0.912 0.00942 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.06 0.904 – 1.24 0.481 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.957 0.834 – 1.1 0.53 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.02 0.987 – 1.06 0.231 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 1.02 0.982 – 1.06 0.332 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.1 0.91 – 1.33 0.327 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.03 0.947 – 1.12 0.508 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.02 0.938 – 1.11 0.614 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.03 0.982 – 1.07 0.245 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.98 0.905 – 1.06 0.627 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.04 0.938 – 1.16 0.435 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.04 0.982 – 1.11 0.175 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.986 0.843 – 1.15 0.862 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.02 0.994 – 1.04 0.136 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.04 1.01 – 1.07 0.0211 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.915 0.799 – 1.05 0.201 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.02 0.97 – 1.07 0.476 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.02 0.951 – 1.09 0.633 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.08 1.02 – 1.13 0.00818 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.962 0.905 – 1.02 0.21 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 0.958 0.898 – 1.02 0.183 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 0.976 0.799 – 1.19 0.811 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.02 0.978 – 1.06 0.399 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 0.974 0.884 – 1.07 0.602 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 0.971 0.815 – 1.16 0.745 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.06 0.988 – 1.13 0.103 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.01 0.903 – 1.12 0.918 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.08 0.943 – 1.23 0.273 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.27 0.956 – 1.68 0.1 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.998 0.979 – 1.02 0.858 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 0.997 0.977 – 1.02 0.78 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 1.05 0.841 – 1.3 0.684 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.09 0.856 – 1.4 0.476 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.05 0.919 – 1.19 0.487 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1.07 0.926 – 1.23 0.364 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.03 0.865 – 1.23 0.73 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.05 0.925 – 1.2 0.432 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 0.991 0.968 – 1.01 0.441 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.994 0.97 – 1.02 0.617 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.943 0.858 – 1.04 0.231 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 0.992 0.933 – 1.06 0.808 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 0.987 0.927 – 1.05 0.682 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 1.05 0.971 – 1.13 0.236 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.874 0.746 – 1.02 0.097 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 0.87 0.743 – 1.02 0.0842 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 1.09 0.833 – 1.43 0.523 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.01 0.85 – 1.19 0.94 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 0.89 0.664 – 1.19 0.437 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.18 0.955 – 1.45 0.126 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.24 1.05 – 1.47 0.0101 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.2 0.992 – 1.44 0.0607 103 1059 all phecode
284 Aplastic anemia Hematopoietic 1.11 1 – 1.22 0.0434 435 4357 all phecode
285 Other anemias Hematopoietic 1.01 0.992 – 1.03 0.253 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.12 0.986 – 1.26 0.0823 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.01 0.937 – 1.09 0.754 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.983 0.889 – 1.09 0.745 414 4147 all phecode
286 Coagulation defects Hematopoietic 1.02 0.953 – 1.09 0.572 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 1.06 0.968 – 1.17 0.199 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 1.12 0.918 – 1.37 0.261 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.07 0.952 – 1.21 0.251 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.05 0.812 – 1.35 0.73 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.856 0.681 – 1.07 0.179 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.969 0.873 – 1.08 0.55 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1 0.954 – 1.06 0.894 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.967 0.803 – 1.16 0.724 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 0.99 0.753 – 1.3 0.94 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 1 0.95 – 1.05 0.977 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1 0.907 – 1.11 0.954 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.01 0.795 – 1.29 0.909 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 1.01 0.975 – 1.04 0.637 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 1.01 0.97 – 1.04 0.733 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 1.01 0.972 – 1.05 0.673 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 1.03 0.82 – 1.29 0.801 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.06 0.984 – 1.13 0.133 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.05 0.93 – 1.18 0.445 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 1.01 0.972 – 1.05 0.549 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 1 0.914 – 1.09 0.997 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 0.99 0.879 – 1.12 0.871 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.11 0.899 – 1.37 0.329 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.977 0.932 – 1.02 0.33 1929 19281 all phecode
290.1 Dementias Mental Disorders 0.99 0.928 – 1.06 0.762 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 1.03 0.931 – 1.13 0.589 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 0.897 0.773 – 1.04 0.153 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.977 0.902 – 1.06 0.575 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.04 0.813 – 1.32 0.78 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.997 0.929 – 1.07 0.941 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.04 0.871 – 1.23 0.69 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.949 0.838 – 1.07 0.405 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 1.02 0.926 – 1.12 0.679 436 4376 all phecode
292 Neurological disorders Mental Disorders 0.983 0.953 – 1.01 0.263 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.997 0.945 – 1.05 0.898 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.966 0.833 – 1.12 0.646 190 1907 all phecode
292.3 Memory loss Mental Disorders 1.03 0.956 – 1.12 0.399 696 6978 all phecode
292.4 Altered mental status Mental Disorders 0.979 0.936 – 1.02 0.34 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 1.03 0.92 – 1.16 0.574 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 0.997 0.953 – 1.04 0.898 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.944 0.882 – 1.01 0.101 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.03 0.961 – 1.11 0.4 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 1.04 0.954 – 1.13 0.387 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 1.09 0.939 – 1.27 0.252 178 1780 all phecode
295.3 Psychosis Mental Disorders 0.978 0.837 – 1.14 0.776 169 1710 all phecode
296 Mood disorders Mental Disorders 0.993 0.975 – 1.01 0.487 12372 123822 all phecode
296.1 Bipolar Mental Disorders 0.994 0.934 – 1.06 0.846 1059 10599 all phecode
296.2 Depression Mental Disorders 0.993 0.974 – 1.01 0.482 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 0.961 0.863 – 1.07 0.474 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.999 0.891 – 1.12 0.981 311 3070 all phecode
300 Anxiety disorders Mental Disorders 1.01 0.982 – 1.03 0.597 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 1.01 0.982 – 1.03 0.571 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1.08 0.915 – 1.27 0.374 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.01 0.931 – 1.09 0.877 707 7065 all phecode
300.13 Phobia Mental Disorders 1.03 0.939 – 1.13 0.532 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.938 0.785 – 1.12 0.476 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 0.839 0.637 – 1.11 0.212 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 1.17 0.975 – 1.4 0.0921 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.1 0.912 – 1.33 0.319 113 1129 all phecode
301 Personality disorders Mental Disorders 1.1 0.984 – 1.23 0.0929 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.22 1.01 – 1.46 0.0373 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.898 0.794 – 1.02 0.0873 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.06 0.968 – 1.17 0.202 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 1.02 0.912 – 1.14 0.744 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 1.27 1.06 – 1.51 0.00932 123 1229 all phecode
304 Adjustment reaction Mental Disorders 1.03 0.918 – 1.17 0.576 293 2936 all phecode
305.2 Eating disorder Mental Disorders 1.03 0.829 – 1.28 0.795 90 900 all phecode
306 Other mental disorder Mental Disorders 0.99 0.978 – 1 0.109 28056 230087 all phecode
306.9 Tension headache Mental Disorders 1.04 0.926 – 1.16 0.525 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 1.1 0.867 – 1.39 0.44 76 770 all phecode
313.3 Autism Mental Disorders 1.23 0.935 – 1.61 0.14 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 1.03 0.925 – 1.15 0.571 351 3517 all phecode
315.1 Learning disorder Mental Disorders 0.977 0.831 – 1.15 0.782 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 1.08 0.87 – 1.33 0.497 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 1.01 0.986 – 1.04 0.317 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.987 0.764 – 1.28 0.923 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 1 0.987 – 1.02 0.601 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 1.01 0.988 – 1.03 0.368 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 0.986 0.919 – 1.06 0.697 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 0.991 0.976 – 1.01 0.213 19359 185465 all phecode
320 Meningitis Neurological 0.99 0.898 – 1.09 0.841 444 4447 all phecode
323 Encephalitis Neurological 0.994 0.888 – 1.11 0.919 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 0.915 0.716 – 1.17 0.482 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 0.948 0.839 – 1.07 0.388 292 2916 all phecode
327 Sleep disorders Neurological 0.939 0.883 – 0.998 0.0422 1164 11659 all phecode
327.3 Sleep apnea Neurological 0.995 0.965 – 1.03 0.747 4428 44318 all phecode
327.4 Insomnia Neurological 0.951 0.806 – 1.12 0.551 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 0.963 0.805 – 1.15 0.684 136 1390 all phecode
331 Other cerebral degenerations Neurological 1.02 0.957 – 1.08 0.597 1142 11416 all phecode
331.1 Hydrocephalus Neurological 1.05 0.956 – 1.15 0.318 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 1.02 0.926 – 1.13 0.662 430 4298 all phecode
332 Parkinson's disease Neurological 0.945 0.888 – 1 0.0712 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.964 0.9 – 1.03 0.308 894 8954 all phecode
333.1 Essential tremor Neurological 0.958 0.83 – 1.11 0.556 216 2157 all phecode
333.2 Myoclonus Neurological 0.989 0.805 – 1.22 0.919 96 958 all phecode
333.4 Torsion dystonia Neurological 1.02 0.901 – 1.16 0.717 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 0.999 0.952 – 1.05 0.964 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 0.956 0.787 – 1.16 0.648 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 1.04 0.91 – 1.18 0.597 245 2446 all phecode
335 Multiple sclerosis Neurological 1.01 0.953 – 1.06 0.801 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 1.01 0.894 – 1.15 0.828 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.13 0.899 – 1.42 0.292 72 719 all phecode
338 Pain Neurological 1.06 0.983 – 1.14 0.131 768 7692 all phecode
338.1 Acute pain Neurological 1.06 0.954 – 1.17 0.288 394 3937 all phecode
338.2 Chronic pain Neurological 1.03 0.927 – 1.15 0.578 380 3817 all phecode
339 Other headache syndromes Neurological 0.992 0.969 – 1.02 0.484 7819 78241 all phecode
340 Migraine Neurological 1.01 0.971 – 1.05 0.651 2860 28602 all phecode
340.1 Migrain with aura Neurological 0.992 0.859 – 1.15 0.918 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.01 0.886 – 1.14 0.926 252 2535 all phecode
342 Hemiplegia Neurological 0.935 0.886 – 0.987 0.0152 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 0.879 0.736 – 1.05 0.151 145 1450 all phecode
344 Other paralytic syndromes Neurological 1.04 0.963 – 1.13 0.301 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.01 0.977 – 1.04 0.704 5023 50270 all phecode
345.1 Epilepsy Neurological 1.03 0.957 – 1.1 0.481 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 1.02 0.926 – 1.12 0.685 439 4385 all phecode
345.12 Partial epilepsy Neurological 1.02 0.9 – 1.15 0.787 277 2776 all phecode
345.3 Convulsions Neurological 1.03 0.984 – 1.07 0.227 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.896 0.758 – 1.06 0.202 144 1438 all phecode
348 Other conditions of brain Neurological 1 0.932 – 1.08 0.921 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 0.994 0.875 – 1.13 0.924 268 2678 all phecode
348.4 Cerebral cysts Neurological 0.883 0.735 – 1.06 0.182 133 1350 all phecode
348.7 Coma Neurological 1 0.9 – 1.12 0.968 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.06 0.936 – 1.21 0.344 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 0.979 0.883 – 1.08 0.682 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.08 0.97 – 1.21 0.158 342 3414 all phecode
350 Abnormal movement Neurological 0.985 0.947 – 1.03 0.472 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 0.988 0.921 – 1.06 0.725 887 8852 all phecode
350.2 Abnormality of gait Neurological 0.985 0.935 – 1.04 0.555 1596 15969 all phecode
350.3 Lack of coordination Neurological 0.961 0.863 – 1.07 0.47 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.929 0.708 – 1.22 0.596 54 540 all phecode
351 Other peripheral nerve disorders Neurological 0.998 0.979 – 1.02 0.795 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 1.02 0.962 – 1.07 0.567 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.959 0.872 – 1.06 0.394 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.03 0.965 – 1.11 0.339 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 1 0.944 – 1.07 0.912 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 1.03 0.852 – 1.25 0.737 114 1138 all phecode
353.2 Nerve root lesions Neurological 1.03 0.79 – 1.34 0.825 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.07 0.912 – 1.26 0.393 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.06 1 – 1.12 0.0478 1361 13648 all phecode
358 Myoneural disorders Neurological 0.903 0.784 – 1.04 0.159 211 2109 all phecode
358.1 Myasthenia gravis Neurological 0.946 0.815 – 1.1 0.461 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 1.04 0.947 – 1.15 0.401 465 4646 all phecode
359.1 Muscular dystrophies Neurological 0.993 0.824 – 1.2 0.945 122 1219 all phecode
359.2 Myopathy Neurological 1.08 0.967 – 1.2 0.172 360 3597 all phecode
360 Disorders of the globe Sense Organs 0.997 0.892 – 1.11 0.955 337 3367 all phecode
360.2 Progressive myopia Sense Organs 1.01 0.888 – 1.15 0.858 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 1 0.967 – 1.04 0.886 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.983 0.929 – 1.04 0.542 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.778 0.603 – 1 0.0539 68 680 all phecode
362 Other retinal disorders Sense Organs 0.982 0.95 – 1.02 0.3 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.02 0.971 – 1.06 0.503 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.01 0.969 – 1.06 0.556 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1 0.853 – 1.18 0.979 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 0.938 0.768 – 1.15 0.533 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.956 0.889 – 1.03 0.216 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.936 0.8 – 1.09 0.406 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.927 0.737 – 1.17 0.519 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.01 0.829 – 1.22 0.958 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.964 0.825 – 1.13 0.643 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 1.18 0.929 – 1.49 0.176 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.04 0.958 – 1.12 0.363 647 6485 all phecode
364.1 Corneal opacity Sense Organs 0.972 0.791 – 1.19 0.784 90 910 all phecode
364.2 Corneal edema Sense Organs 0.824 0.654 – 1.04 0.103 79 800 all phecode
364.4 Corneal degenerations Sense Organs 1.07 0.924 – 1.23 0.374 201 2017 all phecode
364.41 Keratoconus Sense Organs 1.04 0.833 – 1.29 0.739 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 1.09 0.942 – 1.25 0.258 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 1.07 0.869 – 1.31 0.543 100 1000 all phecode
365 Glaucoma Sense Organs 0.98 0.95 – 1.01 0.199 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 1.04 0.979 – 1.11 0.192 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.04 0.977 – 1.11 0.208 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.994 0.92 – 1.07 0.883 698 6996 all phecode
366 Cataract Sense Organs 1.01 0.992 – 1.02 0.381 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 0.942 0.744 – 1.19 0.62 69 700 all phecode
366.2 Senile cataract Sense Organs 1.02 0.993 – 1.04 0.174 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 1.11 0.908 – 1.36 0.309 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.02 0.978 – 1.06 0.361 2408 24092 all phecode
367.1 Myopia Sense Organs 1.02 0.962 – 1.08 0.508 1251 12519 all phecode
367.2 Astigmatism Sense Organs 1.05 0.902 – 1.21 0.549 190 1899 all phecode
367.8 Hypermetropia Sense Organs 1 0.881 – 1.14 0.997 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 1.01 0.938 – 1.09 0.758 719 7198 all phecode
368 Visual disturbances Sense Organs 0.971 0.935 – 1.01 0.128 2962 29648 all phecode
368.1 Amblyopia Sense Organs 0.939 0.858 – 1.03 0.177 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.96 0.889 – 1.04 0.289 727 7288 all phecode
368.3 Anisometropia Sense Organs 1.21 1.03 – 1.43 0.0196 154 1548 all phecode
368.4 Visual field defects Sense Organs 0.973 0.87 – 1.09 0.633 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 0.957 0.88 – 1.04 0.302 612 6115 all phecode
369 Infection of the eye Sense Organs 1.02 0.939 – 1.12 0.585 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 1.01 0.843 – 1.21 0.913 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.978 0.851 – 1.12 0.751 213 2128 all phecode
370 Keratitis Sense Organs 0.977 0.867 – 1.1 0.709 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 0.925 0.779 – 1.1 0.378 141 1408 all phecode
371 Inflammation of the eye Sense Organs 0.969 0.934 – 1.01 0.103 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.859 0.781 – 0.945 0.00175 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 0.986 0.945 – 1.03 0.51 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 0.983 0.912 – 1.06 0.653 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 1.01 0.985 – 1.04 0.379 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 0.973 0.914 – 1.04 0.401 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 1.03 0.983 – 1.08 0.206 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 0.99 0.948 – 1.03 0.648 2204 22031 all phecode
375.2 Epiphora Sense Organs 1.01 0.943 – 1.08 0.771 898 8969 all phecode
376 Disorders of the orbit Sense Organs 0.802 0.638 – 1.01 0.0583 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.983 0.881 – 1.1 0.764 361 3618 all phecode
377.1 Optic atrophy Sense Organs 0.862 0.646 – 1.15 0.311 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.998 0.833 – 1.2 0.986 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.964 0.912 – 1.02 0.191 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.95 0.887 – 1.02 0.142 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.02 0.889 – 1.17 0.775 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 0.929 0.82 – 1.05 0.249 275 2755 all phecode
379 Other disorders of eye Sense Organs 1 0.969 – 1.04 0.879 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 1.02 0.965 – 1.08 0.489 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 1 0.956 – 1.05 0.88 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.15 0.898 – 1.46 0.274 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.874 0.787 – 0.971 0.0123 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.01 0.861 – 1.18 0.906 169 1690 all phecode
380 Disorders of external ear Sense Organs 1 0.923 – 1.08 0.991 642 6413 all phecode
380.1 Otitis externa Sense Organs 0.923 0.844 – 1.01 0.082 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 1.06 0.949 – 1.17 0.32 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.975 0.932 – 1.02 0.263 2150 21493 all phecode
381.1 Otitis media Sense Organs 0.97 0.923 – 1.02 0.218 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.948 0.883 – 1.02 0.134 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 1 0.862 – 1.16 0.999 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 0.941 0.806 – 1.1 0.44 171 1709 all phecode
381.9 Otorrhea Sense Organs 0.958 0.847 – 1.08 0.497 281 2807 all phecode
382 Otalgia Sense Organs 1.02 0.906 – 1.14 0.792 308 3084 all phecode
383 Otosclerosis Sense Organs 0.915 0.812 – 1.03 0.146 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 0.968 0.914 – 1.02 0.254 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 0.967 0.908 – 1.03 0.302 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.991 0.92 – 1.07 0.805 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 1.02 0.936 – 1.11 0.68 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.01 0.884 – 1.16 0.876 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.977 0.929 – 1.03 0.354 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 0.997 0.914 – 1.09 0.939 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 0.947 0.851 – 1.06 0.326 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 0.979 0.908 – 1.05 0.573 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.979 0.95 – 1.01 0.176 4582 45806 all phecode
388 Other disorders of ear Sense Organs 0.971 0.841 – 1.12 0.691 202 2017 all phecode
389 Hearing loss Sense Organs 0.994 0.963 – 1.03 0.717 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 1.02 0.931 – 1.13 0.628 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 1.04 0.944 – 1.15 0.429 450 4497 all phecode
389.4 Tinnitus Sense Organs 0.915 0.834 – 1 0.0579 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.01 0.977 – 1.04 0.708 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 0.991 0.955 – 1.03 0.655 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 1.01 0.953 – 1.07 0.754 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 0.988 0.927 – 1.05 0.7 1058 10566 all phecode
395 Heart valve disorders Circulatory System 1 0.973 – 1.04 0.812 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.993 0.956 – 1.03 0.722 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.06 0.94 – 1.2 0.341 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 0.993 0.812 – 1.21 0.945 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.977 0.796 – 1.2 0.827 97 970 all phecode
395.6 Heart valve replaced Circulatory System 1.04 0.989 – 1.1 0.121 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 0.997 0.936 – 1.06 0.932 1048 10468 all phecode
401 Hypertension Circulatory System 1.01 0.998 – 1.01 0.153 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 1.01 0.998 – 1.01 0.167 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.03 0.982 – 1.08 0.222 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 1.02 0.918 – 1.14 0.693 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.03 0.976 – 1.08 0.287 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 1.03 0.862 – 1.22 0.777 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 0.986 0.935 – 1.04 0.618 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 1 0.992 – 1.02 0.469 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.985 0.957 – 1.01 0.308 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 1.01 0.996 – 1.03 0.126 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 0.991 0.975 – 1.01 0.285 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 1 0.99 – 1.02 0.525 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.01 0.934 – 1.09 0.816 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.01 0.99 – 1.02 0.412 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.967 0.912 – 1.03 0.272 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 0.985 0.938 – 1.03 0.532 1823 18228 all phecode
414.2 ASCVD Circulatory System 0.948 0.748 – 1.2 0.661 72 719 all phecode
415 Pulmonary heart disease Circulatory System 1.01 0.984 – 1.05 0.358 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.05 0.84 – 1.31 0.67 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.993 0.913 – 1.08 0.861 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 0.991 0.9 – 1.09 0.861 448 4475 all phecode
416 Cardiomegaly Circulatory System 1.03 0.99 – 1.07 0.143 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 0.998 0.986 – 1.01 0.733 28599 270106 all phecode
418.1 Precordial pain Circulatory System 1.02 0.983 – 1.05 0.32 3551 35541 all phecode
420 Carditis Circulatory System 1.02 0.971 – 1.06 0.499 2106 21053 all phecode
420.1 Myocarditis Circulatory System 0.954 0.794 – 1.15 0.618 127 1267 all phecode
420.2 Pericarditis Circulatory System 1.01 0.95 – 1.06 0.849 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 0.976 0.851 – 1.12 0.728 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 1.02 0.839 – 1.23 0.877 113 1129 all phecode
420.3 Endocarditis Circulatory System 1.03 0.958 – 1.12 0.391 719 7194 all phecode
425 Cardiomyopathy Circulatory System 0.962 0.907 – 1.02 0.187 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.966 0.911 – 1.03 0.256 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.07 0.891 – 1.27 0.49 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.841 0.712 – 0.994 0.0425 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 0.873 0.676 – 1.13 0.302 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 0.991 0.966 – 1.02 0.458 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 0.992 0.948 – 1.04 0.722 2114 21162 all phecode
426.21 First degree AV block Circulatory System 0.986 0.923 – 1.05 0.672 986 9867 all phecode
426.23 Second degree AV block Circulatory System 0.997 0.905 – 1.1 0.946 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.01 0.929 – 1.1 0.792 587 5868 all phecode
426.25 Other heart block Circulatory System 0.856 0.711 – 1.03 0.101 131 1318 all phecode
426.3 Bundle branch block Circulatory System 1.01 0.971 – 1.04 0.741 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 0.992 0.941 – 1.05 0.78 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 1.01 0.959 – 1.06 0.769 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.958 0.837 – 1.1 0.527 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.17 0.911 – 1.51 0.217 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.974 0.935 – 1.02 0.222 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.989 0.947 – 1.03 0.628 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 1 0.989 – 1.02 0.698 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 0.99 0.955 – 1.03 0.596 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.977 0.937 – 1.02 0.284 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.01 0.948 – 1.08 0.689 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1 0.988 – 1.02 0.579 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1 0.966 – 1.04 0.904 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.984 0.927 – 1.05 0.611 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.968 0.866 – 1.08 0.564 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 1 0.935 – 1.07 0.991 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.993 0.929 – 1.06 0.844 952 9541 all phecode
427.6 Premature beats Circulatory System 1.04 0.954 – 1.14 0.357 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 1 0.824 – 1.22 0.976 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 1.04 0.998 – 1.09 0.059 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.04 0.939 – 1.15 0.457 402 4029 all phecode
427.9 Palpitations Circulatory System 1.01 0.973 – 1.04 0.75 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.98 0.953 – 1.01 0.142 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1 0.958 – 1.05 0.933 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 0.98 0.95 – 1.01 0.189 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.02 0.941 – 1.1 0.672 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 1.02 0.795 – 1.32 0.856 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.05 0.962 – 1.15 0.258 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 0.927 0.796 – 1.08 0.333 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 0.997 0.95 – 1.05 0.888 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.994 0.926 – 1.07 0.875 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1.01 0.937 – 1.09 0.797 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 0.973 0.858 – 1.1 0.675 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 0.988 0.966 – 1.01 0.288 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.943 0.888 – 1 0.0542 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 0.925 0.804 – 1.06 0.277 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.988 0.958 – 1.02 0.474 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.993 0.944 – 1.04 0.775 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 0.989 0.952 – 1.03 0.586 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 0.989 0.946 – 1.03 0.623 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 1.08 0.979 – 1.2 0.122 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.938 0.884 – 0.994 0.0312 1279 12783 all phecode
440 Atherosclerosis Circulatory System 1.01 0.955 – 1.07 0.749 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.945 0.78 – 1.14 0.558 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.03 0.957 – 1.11 0.441 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 0.963 0.85 – 1.09 0.551 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 0.958 0.882 – 1.04 0.299 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.98 0.87 – 1.1 0.745 283 2827 all phecode
442 Other aneurysm Circulatory System 0.999 0.952 – 1.05 0.965 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 0.994 0.942 – 1.05 0.839 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.951 0.889 – 1.02 0.146 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 0.908 0.736 – 1.12 0.368 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.944 0.806 – 1.11 0.476 169 1696 all phecode
442.4 Arterial dissection Circulatory System 1.12 0.844 – 1.49 0.431 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.01 0.873 – 1.17 0.896 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 1.03 0.994 – 1.06 0.114 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 1.03 0.968 – 1.09 0.368 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.07 0.961 – 1.18 0.227 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.02 0.99 – 1.06 0.162 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.01 0.973 – 1.05 0.518 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.03 0.966 – 1.1 0.34 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.05 0.966 – 1.15 0.243 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.03 0.955 – 1.1 0.484 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 1.14 0.986 – 1.33 0.0755 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 1.03 0.928 – 1.14 0.58 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 0.991 0.87 – 1.13 0.888 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 0.977 0.923 – 1.03 0.414 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 0.973 0.908 – 1.04 0.438 868 8712 all phecode
448 Disease of capillaries Circulatory System 1.09 0.917 – 1.29 0.334 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.05 0.973 – 1.14 0.209 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.991 0.959 – 1.02 0.601 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.991 0.958 – 1.03 0.596 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.971 0.89 – 1.06 0.51 564 5645 all phecode
454 Varicose veins Circulatory System 1.01 0.991 – 1.03 0.297 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1.01 0.989 – 1.03 0.41 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.04 0.96 – 1.13 0.329 624 6325 all phecode
455 Hemorrhoids Circulatory System 1.01 0.993 – 1.02 0.323 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.02 0.871 – 1.18 0.846 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.977 0.798 – 1.19 0.817 97 967 all phecode
458 Hypotension Circulatory System 1 0.976 – 1.03 0.863 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 1 0.945 – 1.06 0.994 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 1 0.872 – 1.15 0.983 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 1.01 0.974 – 1.04 0.622 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 0.994 0.978 – 1.01 0.449 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 1.04 0.873 – 1.23 0.682 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 0.993 0.977 – 1.01 0.425 16103 159422 all phecode
464 Acute sinusitis Respiratory 1.01 0.868 – 1.17 0.938 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.999 0.957 – 1.04 0.951 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 1.01 0.94 – 1.08 0.799 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.993 0.85 – 1.16 0.934 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.995 0.966 – 1.03 0.758 4654 46553 all phecode
471 Nasal polyps Respiratory 1 0.968 – 1.04 0.851 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.986 0.922 – 1.05 0.672 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1.01 0.974 – 1.06 0.49 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 1.13 0.922 – 1.38 0.241 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.02 0.905 – 1.16 0.704 264 2647 all phecode
473.4 Voice disturbance Respiratory 1.01 0.947 – 1.07 0.789 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 1.02 0.969 – 1.07 0.472 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 1.02 0.937 – 1.11 0.635 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.04 0.978 – 1.11 0.208 1122 11199 all phecode
475 Chronic sinusitis Respiratory 0.967 0.929 – 1.01 0.105 2589 25882 all phecode
476 Allergic rhinitis Respiratory 0.999 0.938 – 1.06 0.974 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1 0.962 – 1.05 0.881 2447 24452 all phecode
478 Throat pain Respiratory 0.962 0.865 – 1.07 0.48 377 3789 all phecode
479 Other upper respiratory disease Respiratory 0.974 0.943 – 1.01 0.102 4074 40737 all phecode
480 Pneumonia Respiratory 1.01 0.992 – 1.03 0.234 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 1.02 0.992 – 1.04 0.189 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.02 0.992 – 1.05 0.172 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 0.912 0.732 – 1.14 0.411 93 929 all phecode
480.2 Viral pneumonia Respiratory 0.911 0.716 – 1.16 0.451 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.18 0.959 – 1.44 0.118 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.959 0.891 – 1.03 0.261 794 7951 all phecode
481 Influenza Respiratory 0.95 0.849 – 1.06 0.373 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.08 0.927 – 1.25 0.337 193 1930 all phecode
495 Asthma Respiratory 1.01 0.997 – 1.02 0.124 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 1.01 0.893 – 1.15 0.833 250 2510 all phecode
496 Chronic airway obstruction Respiratory 0.997 0.977 – 1.02 0.779 10424 101546 all phecode
496.1 Emphysema Respiratory 1.01 0.963 – 1.06 0.657 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 0.997 0.96 – 1.04 0.877 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1 0.963 – 1.04 0.925 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 0.993 0.947 – 1.04 0.777 1885 18859 all phecode
497 Bronchitis Respiratory 1.04 0.958 – 1.13 0.353 626 6267 all phecode
500 Lung disease due to external agents Respiratory 0.998 0.902 – 1.1 0.961 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.785 0.621 – 0.991 0.0422 79 784 all phecode
500.2 Pneumoconiosis Respiratory 1.02 0.9 – 1.16 0.725 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.07 0.992 – 1.16 0.0795 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.992 0.926 – 1.06 0.817 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1 0.917 – 1.1 0.927 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.999 0.893 – 1.12 0.992 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.21 0.947 – 1.56 0.126 61 610 all phecode
506 Empyema and pneumothorax Respiratory 1 0.945 – 1.07 0.892 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 1.02 0.994 – 1.05 0.135 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.01 0.969 – 1.06 0.538 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.987 0.947 – 1.03 0.513 2599 26031 all phecode
509.1 Respiratory failure Respiratory 0.974 0.931 – 1.02 0.262 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 0.962 0.916 – 1.01 0.125 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 0.961 0.812 – 1.14 0.645 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.05 0.943 – 1.16 0.384 386 3863 all phecode
510 Other diseases of lung Respiratory 0.945 0.877 – 1.02 0.138 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 0.996 0.974 – 1.02 0.692 9031 90349 all phecode
512.1 Wheezing Respiratory 1.01 0.88 – 1.16 0.882 220 2196 all phecode
512.2 Painful respiration Respiratory 0.986 0.858 – 1.13 0.844 207 2075 all phecode
512.7 Shortness of breath Respiratory 0.998 0.972 – 1.03 0.897 5842 58498 all phecode
512.8 Cough Respiratory 0.965 0.929 – 1 0.071 2866 28642 all phecode
512.9 Other dyspnea Respiratory 1.03 0.966 – 1.11 0.338 914 9124 all phecode
513 Respiratory abnormalities Respiratory 1.01 0.929 – 1.1 0.837 611 6112 all phecode
513.3 Hypoventilation Respiratory 0.983 0.782 – 1.24 0.881 83 830 all phecode
513.4 Hyperventilation Respiratory 0.993 0.878 – 1.12 0.915 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 0.99 0.84 – 1.17 0.907 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 0.99 0.95 – 1.03 0.634 2465 24673 all phecode
516 Abnormal sputum Respiratory 1.02 0.975 – 1.07 0.41 2132 21335 all phecode
516.1 Hemoptysis Respiratory 1.02 0.975 – 1.07 0.392 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.01 0.991 – 1.03 0.251 9366 93681 all phecode
519.2 Respiratory complications Respiratory 1.06 0.944 – 1.18 0.335 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.01 0.986 – 1.03 0.495 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.04 0.929 – 1.17 0.493 303 3049 all phecode
520 Disorders of tooth development Digestive 0.998 0.953 – 1.04 0.917 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.02 0.777 – 1.34 0.879 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 0.998 0.957 – 1.04 0.938 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 0.993 0.956 – 1.03 0.71 3016 30245 all phecode
521.1 Dental caries Digestive 0.997 0.961 – 1.04 0.885 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 1 0.955 – 1.05 0.917 1774 17750 all phecode
522.5 Periapical abscess Digestive 0.988 0.931 – 1.05 0.699 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 0.982 0.934 – 1.03 0.491 1681 16812 all phecode
523.1 Gingivitis Digestive 1.01 0.823 – 1.23 0.952 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 0.98 0.922 – 1.04 0.511 1165 11650 all phecode
523.31 Acute periodontitis Digestive 0.979 0.903 – 1.06 0.603 666 6667 all phecode
523.32 Chronic periodontitis Digestive 1.01 0.924 – 1.1 0.875 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.975 0.87 – 1.09 0.668 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1 0.89 – 1.13 0.971 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.01 0.974 – 1.05 0.515 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.957 0.749 – 1.22 0.723 72 720 all phecode
526 Diseases of the jaws Digestive 0.971 0.908 – 1.04 0.397 928 9279 all phecode
526.1 Cysts of the jaws Digestive 0.917 0.819 – 1.03 0.13 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.84 0.644 – 1.1 0.198 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.01 0.886 – 1.15 0.87 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1 0.879 – 1.15 0.945 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.988 0.812 – 1.2 0.9 110 1098 all phecode
526.9 Jaw disease NOS Digestive 1.08 0.942 – 1.24 0.273 233 2329 all phecode
527 Diseases of the salivary glands Digestive 0.985 0.911 – 1.06 0.697 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.14 0.914 – 1.42 0.245 84 838 all phecode
527.2 Sialoadenitis Digestive 0.933 0.837 – 1.04 0.205 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 0.989 0.755 – 1.3 0.935 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.1 0.911 – 1.32 0.33 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1 0.972 – 1.04 0.799 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 1.01 0.923 – 1.11 0.781 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.01 0.91 – 1.12 0.874 389 3884 all phecode
528.12 Oral aphthae Digestive 1.06 0.851 – 1.33 0.592 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.999 0.857 – 1.16 0.988 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 0.98 0.813 – 1.18 0.836 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 0.986 0.798 – 1.22 0.897 94 940 all phecode
528.5 Diseases of lips Digestive 1.06 0.981 – 1.15 0.142 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.02 0.907 – 1.15 0.741 308 3079 all phecode
528.7 Sialolithiasis Digestive 0.982 0.874 – 1.1 0.761 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 1.02 0.958 – 1.08 0.59 1232 12312 all phecode
529.1 Glossitis Digestive 0.979 0.87 – 1.1 0.727 299 2986 all phecode
530 Diseases of esophagus Digestive 1.01 0.998 – 1.02 0.101 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.01 0.997 – 1.02 0.151 31253 272429 all phecode
530.11 GERD Digestive 1.01 0.993 – 1.02 0.354 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 1.03 1 – 1.06 0.0366 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 1.01 0.99 – 1.03 0.303 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.01 0.959 – 1.06 0.754 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.04 0.993 – 1.09 0.0984 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 1.01 0.932 – 1.1 0.785 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.827 0.699 – 0.978 0.0263 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.976 0.874 – 1.09 0.658 341 3416 all phecode
530.9 Heartburn Digestive 1.01 0.969 – 1.06 0.556 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1 0.976 – 1.03 0.973 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.981 0.905 – 1.06 0.649 637 6374 all phecode
531.2 Gastric ulcer Digestive 0.999 0.967 – 1.03 0.953 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 0.991 0.954 – 1.03 0.627 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 0.991 0.897 – 1.1 0.861 427 4268 all phecode
532 Dysphagia Digestive 1.02 0.993 – 1.05 0.155 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 0.999 0.987 – 1.01 0.934 28078 261548 all phecode
535.1 Acute gastritis Digestive 0.963 0.907 – 1.02 0.214 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 1.08 0.973 – 1.21 0.145 370 3687 all phecode
535.6 Duodenitis Digestive 1 0.98 – 1.03 0.791 7592 75928 all phecode
535.8 Other specified gastritis Digestive 0.999 0.977 – 1.02 0.954 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.943 0.785 – 1.13 0.533 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.01 0.893 – 1.15 0.846 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 0.993 0.958 – 1.03 0.695 3391 33907 all phecode
540 Appendiceal conditions Digestive 0.996 0.96 – 1.03 0.829 3088 30890 all phecode
540.1 Appendicitis Digestive 0.995 0.957 – 1.03 0.78 2895 28963 all phecode
540.11 Acute appendicitis Digestive 1 0.961 – 1.04 0.972 2601 26019 all phecode
550 Abdominal hernia Digestive 1 0.993 – 1.01 0.526 45429 282640 all phecode
550.1 Inguinal hernia Digestive 1 0.986 – 1.02 0.75 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 1.01 0.994 – 1.02 0.314 26494 238953 all phecode
550.3 Femoral hernia Digestive 1.01 0.93 – 1.09 0.826 651 6504 all phecode
550.4 Umbilical hernia Digestive 0.985 0.953 – 1.02 0.392 3705 37072 all phecode
550.5 Ventral hernia Digestive 0.999 0.964 – 1.03 0.959 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 0.99 0.96 – 1.02 0.527 4444 44442 all phecode
555.1 Regional enteritis Digestive 0.998 0.949 – 1.05 0.924 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 0.991 0.956 – 1.03 0.634 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.1 1 – 1.2 0.041 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 1.05 0.986 – 1.12 0.127 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 1.03 0.952 – 1.12 0.459 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.809 0.715 – 0.915 0.000749 299 2987 all phecode
557.1 Celiac disease Digestive 1 0.957 – 1.05 0.872 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 1 0.987 – 1.02 0.645 15492 155105 all phecode
559 Ileostomy status Digestive 1.03 0.976 – 1.08 0.305 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.02 0.992 – 1.06 0.146 3936 39337 all phecode
560.1 Paralytic ileus Digestive 0.997 0.911 – 1.09 0.946 523 5231 all phecode
560.2 Impaction of intestine Digestive 1.06 0.94 – 1.2 0.323 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.993 0.924 – 1.07 0.839 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 1.03 0.992 – 1.06 0.137 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 0.998 0.982 – 1.01 0.83 15772 157686 all phecode
561.1 Diarrhea Digestive 1.03 0.935 – 1.13 0.563 466 4653 all phecode
561.2 Flatulence Digestive 1.02 0.967 – 1.07 0.519 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 1.02 1.01 – 1.03 0.00129 26714 211692 all phecode
562.1 Diverticulosis Digestive 1.02 1.01 – 1.03 0.000917 26672 211642 all phecode
563 Constipation Digestive 1 0.98 – 1.02 0.997 10314 103140 all phecode
564 Functional digestive disorders Digestive 1 0.99 – 1.02 0.548 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.01 0.986 – 1.04 0.341 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 0.979 0.93 – 1.03 0.412 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 1 0.985 – 1.02 0.841 15186 151648 all phecode
565 Anal and rectal conditions Digestive 1 0.987 – 1.02 0.628 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 1.01 0.986 – 1.03 0.423 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.02 0.949 – 1.09 0.661 929 9293 all phecode
568 Other disorders of peritoneum Digestive 0.998 0.963 – 1.03 0.918 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.994 0.958 – 1.03 0.741 3101 30987 all phecode
569 Other disorders of intestine Digestive 1 0.972 – 1.04 0.841 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.996 0.838 – 1.18 0.966 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 1.01 0.916 – 1.1 0.909 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 1 0.967 – 1.04 0.83 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.02 0.966 – 1.07 0.556 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.02 0.845 – 1.24 0.818 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 1.09 0.966 – 1.24 0.155 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.967 0.905 – 1.03 0.323 976 9804 all phecode
571.81 Portal hypertension Digestive 0.963 0.881 – 1.05 0.41 528 5285 all phecode
572 Ascites (non malignant) Digestive 0.993 0.942 – 1.05 0.783 1544 15454 all phecode
573 Other disorders of liver Digestive 1.02 0.965 – 1.07 0.531 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 0.957 0.779 – 1.17 0.672 96 960 all phecode
573.3 Hepatomegaly Digestive 0.965 0.855 – 1.09 0.569 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 0.998 0.931 – 1.07 0.949 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 1.01 0.978 – 1.05 0.482 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 0.969 0.837 – 1.12 0.676 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 1 0.986 – 1.02 0.782 15607 156123 all phecode
574.1 Cholelithiasis Digestive 0.996 0.979 – 1.01 0.684 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.972 0.922 – 1.03 0.295 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.987 0.96 – 1.02 0.363 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 1.01 0.968 – 1.05 0.701 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.01 0.97 – 1.05 0.654 2748 27523 all phecode
575 Other biliary tract disease Digestive 0.989 0.957 – 1.02 0.512 3867 38724 all phecode
575.1 Cholangitis Digestive 0.95 0.865 – 1.04 0.281 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 1.02 0.944 – 1.09 0.677 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.953 0.866 – 1.05 0.331 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 0.992 0.939 – 1.05 0.777 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 0.965 0.906 – 1.03 0.278 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.03 0.924 – 1.15 0.573 348 3488 all phecode
577 Diseases of pancreas Digestive 1.03 0.994 – 1.08 0.0987 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 1.03 0.98 – 1.07 0.278 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 1.03 0.938 – 1.13 0.557 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.11 1 – 1.24 0.0473 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.992 – 1.02 0.382 20626 206278 all phecode
578.1 Hematemesis Digestive 0.967 0.923 – 1.01 0.156 1958 19564 all phecode
578.2 Blood in stool Digestive 0.959 0.921 – 0.999 0.043 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.01 0.993 – 1.03 0.237 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.01 0.982 – 1.04 0.492 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.95 0.902 – 1 0.057 1548 15498 all phecode
579.2 Splenomegaly Digestive 0.943 0.853 – 1.04 0.25 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.02 0.966 – 1.07 0.543 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.991 0.94 – 1.04 0.74 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 1.02 0.956 – 1.09 0.568 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.915 0.729 – 1.15 0.444 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.1 0.923 – 1.31 0.288 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.01 0.946 – 1.09 0.683 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.03 0.938 – 1.14 0.516 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.893 0.782 – 1.02 0.0911 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.893 0.784 – 1.02 0.0906 253 2529 all phecode
585 Renal failure Genitourinary 1.01 0.983 – 1.03 0.556 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 1.01 0.984 – 1.05 0.365 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 1.04 0.982 – 1.09 0.189 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.02 0.977 – 1.06 0.401 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 0.958 0.873 – 1.05 0.367 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 0.976 0.941 – 1.01 0.175 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.01 0.874 – 1.16 0.906 208 2089 all phecode
586.11 Small kidney Genitourinary 0.973 0.835 – 1.13 0.725 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.01 0.95 – 1.07 0.816 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.884 0.705 – 1.11 0.288 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.945 0.883 – 1.01 0.109 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 0.966 0.867 – 1.08 0.529 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 0.843 0.684 – 1.04 0.109 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.01 0.839 – 1.22 0.894 116 1158 all phecode
590 Pyelonephritis Genitourinary 1.03 0.978 – 1.09 0.231 1328 13285 all phecode
591 Urinary tract infection Genitourinary 0.998 0.979 – 1.02 0.804 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 1.04 0.998 – 1.08 0.0656 2966 29661 all phecode
592.1 Cystitis Genitourinary 1.04 0.999 – 1.08 0.0556 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 0.955 0.805 – 1.13 0.599 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 1.05 0.978 – 1.12 0.191 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 1.09 0.955 – 1.23 0.207 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.1 0.944 – 1.29 0.219 165 1662 all phecode
593 Hematuria Genitourinary 1 0.988 – 1.02 0.655 16068 160204 all phecode
594 Urinary calculus Genitourinary 0.995 0.969 – 1.02 0.675 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 0.995 0.96 – 1.03 0.809 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 0.976 0.907 – 1.05 0.524 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 1 0.963 – 1.05 0.848 2401 24024 all phecode
594.8 Renal colic Genitourinary 1.01 0.968 – 1.06 0.594 2050 20500 all phecode
595 Hydronephrosis Genitourinary 0.999 0.954 – 1.05 0.969 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 1 0.983 – 1.02 0.716 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 0.997 0.952 – 1.04 0.888 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 0.982 0.933 – 1.03 0.471 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.02 0.983 – 1.05 0.341 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1 0.967 – 1.04 0.903 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 1.01 0.805 – 1.27 0.913 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 1 0.97 – 1.04 0.828 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.877 0.778 – 0.989 0.0327 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1 0.989 – 1.02 0.575 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 1.13 0.969 – 1.32 0.119 166 1670 all phecode
599.2 Retention of urine Genitourinary 0.977 0.952 – 1 0.0673 6718 67168 all phecode
599.3 Dysuria Genitourinary 1.01 0.952 – 1.07 0.735 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 0.991 0.97 – 1.01 0.443 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.01 0.977 – 1.04 0.561 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 1.08 0.891 – 1.32 0.426 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.19 0.913 – 1.55 0.2 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 1.02 0.975 – 1.07 0.377 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 1 0.983 – 1.02 0.761 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 1.03 0.981 – 1.07 0.268 2081 20818 all phecode
601.1 Prostatitis Genitourinary 1.02 0.968 – 1.07 0.467 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 1.03 0.903 – 1.18 0.63 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 1.03 0.96 – 1.1 0.435 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 1 0.762 – 1.32 0.988 59 588 all phecode
601.4 Balanoposthitis Genitourinary 0.956 0.846 – 1.08 0.462 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.05 0.935 – 1.18 0.411 303 3019 all phecode
602 Other disorders of prostate Genitourinary 1.02 0.965 – 1.08 0.49 1341 13408 all phecode
603 Other disorders of testis Genitourinary 0.981 0.939 – 1.03 0.406 2150 21512 all phecode
603.1 Hydrocele Genitourinary 0.947 0.895 – 1 0.0563 1339 13402 all phecode
604 Disorders of penis Genitourinary 0.986 0.952 – 1.02 0.454 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.99 0.952 – 1.03 0.605 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.04 0.92 – 1.17 0.553 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 0.975 0.938 – 1.01 0.207 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.03 0.896 – 1.2 0.641 214 2138 all phecode
609.1 Infertility, male Genitourinary 0.958 0.745 – 1.23 0.737 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 1.05 0.9 – 1.23 0.519 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 0.986 0.946 – 1.03 0.498 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 1.02 0.953 – 1.09 0.577 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.02 0.908 – 1.15 0.716 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 0.984 0.874 – 1.11 0.788 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.979 0.926 – 1.03 0.455 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1 0.929 – 1.09 0.906 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.01 0.955 – 1.06 0.818 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 1.07 0.826 – 1.39 0.603 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 1.01 0.955 – 1.06 0.817 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.962 0.897 – 1.03 0.27 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.963 0.898 – 1.03 0.302 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 1.16 0.915 – 1.46 0.226 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 1 0.954 – 1.06 0.897 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.03 0.952 – 1.11 0.47 720 7210 all phecode
613.5 Mastodynia Genitourinary 0.903 0.714 – 1.14 0.394 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 1.02 0.95 – 1.11 0.529 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 1.01 0.904 – 1.13 0.846 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 1.1 0.952 – 1.26 0.201 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.972 0.946 – 0.999 0.044 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.962 0.923 – 1 0.0622 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.01 0.94 – 1.08 0.81 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.19 0.941 – 1.5 0.146 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.01 0.915 – 1.12 0.824 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.05 0.948 – 1.17 0.327 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.02 0.903 – 1.15 0.764 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.973 0.934 – 1.01 0.188 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.985 0.931 – 1.04 0.607 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.906 0.819 – 1 0.0543 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.01 0.934 – 1.08 0.875 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.978 0.866 – 1.1 0.716 274 2737 all phecode
615 Endometriosis Genitourinary 0.98 0.949 – 1.01 0.226 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.03 0.92 – 1.16 0.576 304 3037 all phecode
618 Genital prolapse Genitourinary 0.997 0.978 – 1.02 0.723 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1 0.978 – 1.03 0.884 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1 0.973 – 1.03 0.961 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.962 0.877 – 1.05 0.407 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.971 0.896 – 1.05 0.467 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.972 0.951 – 0.994 0.0135 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.939 0.87 – 1.01 0.108 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 0.994 0.959 – 1.03 0.759 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.962 0.926 – 1 0.05 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1 0.955 – 1.05 0.935 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.981 0.927 – 1.04 0.496 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 0.871 0.683 – 1.11 0.263 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 1 0.941 – 1.06 0.999 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 1.02 1 – 1.04 0.0549 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 1.03 1 – 1.05 0.0283 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 1.01 0.98 – 1.05 0.404 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 0.979 0.924 – 1.04 0.48 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 0.969 0.9 – 1.04 0.398 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.956 0.838 – 1.09 0.507 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.978 0.886 – 1.08 0.665 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 0.986 0.96 – 1.01 0.306 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.964 0.928 – 1 0.0628 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 1.02 0.958 – 1.08 0.594 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1 0.987 – 1.02 0.686 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1 0.983 – 1.02 0.999 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.951 0.782 – 1.16 0.613 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.01 0.987 – 1.03 0.455 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 0.983 0.939 – 1.03 0.452 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.986 0.953 – 1.02 0.398 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 1.02 0.97 – 1.07 0.457 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.971 0.827 – 1.14 0.72 159 1587 all phecode
626.8 Infertility, female Genitourinary 1.03 0.977 – 1.09 0.248 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.997 0.977 – 1.02 0.76 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 0.999 0.978 – 1.02 0.949 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 0.914 0.785 – 1.06 0.245 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.965 0.906 – 1.03 0.26 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.944 0.841 – 1.06 0.335 310 3097 all phecode
628 Ovarian cyst Genitourinary 0.962 0.934 – 0.992 0.012 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.02 0.987 – 1.05 0.287 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.08 1.01 – 1.14 0.0159 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.96 0.856 – 1.08 0.483 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.992 0.946 – 1.04 0.745 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.973 0.906 – 1.04 0.451 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.02 0.965 – 1.08 0.449 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.998 0.956 – 1.04 0.925 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.916 0.842 – 0.996 0.0405 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.992 0.932 – 1.06 0.8 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 0.938 0.739 – 1.19 0.6 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.994 0.934 – 1.06 0.845 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.955 0.85 – 1.07 0.434 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.943 0.819 – 1.09 0.416 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.949 0.804 – 1.12 0.535 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.01 0.957 – 1.08 0.62 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.02 0.977 – 1.07 0.347 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.935 0.728 – 1.2 0.597 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.976 0.862 – 1.11 0.701 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.979 0.808 – 1.19 0.831 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.05 0.904 – 1.22 0.53 193 1922 all phecode
650 Normal delivery Pregnancy Complications 1 0.958 – 1.05 0.855 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 0.954 0.852 – 1.07 0.414 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1.01 0.96 – 1.06 0.701 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.968 0.916 – 1.02 0.256 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.27 1 – 1.61 0.0462 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.983 0.951 – 1.02 0.289 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.798 0.653 – 0.976 0.0284 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.996 0.953 – 1.04 0.854 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.967 0.884 – 1.06 0.465 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 1.01 0.98 – 1.04 0.518 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.987 0.947 – 1.03 0.525 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.07 0.904 – 1.26 0.447 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.04 0.911 – 1.18 0.59 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.14 0.889 – 1.45 0.308 63 624 all phecode
679 Complications of in utero procedures Dermatologic 0.89 0.674 – 1.18 0.413 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.01 0.988 – 1.04 0.345 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.08 0.995 – 1.18 0.0665 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.95 0.868 – 1.04 0.259 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1 0.974 – 1.03 0.911 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1 0.973 – 1.03 0.98 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.998 0.971 – 1.03 0.916 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.06 0.974 – 1.15 0.183 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1 0.946 – 1.06 0.985 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.01 0.969 – 1.06 0.596 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 1.07 0.987 – 1.17 0.0977 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 0.987 0.886 – 1.1 0.817 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1.01 0.921 – 1.1 0.903 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.955 0.913 – 0.999 0.0441 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 0.977 0.865 – 1.1 0.709 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 1.11 0.907 – 1.36 0.312 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.02 0.978 – 1.06 0.399 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.988 0.961 – 1.02 0.381 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.969 0.771 – 1.22 0.784 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 1.03 0.795 – 1.34 0.813 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 1.15 0.958 – 1.38 0.132 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 1.02 0.956 – 1.09 0.552 986 9854 all phecode
694.1 Vitiligo Dermatologic 0.901 0.689 – 1.18 0.447 60 599 all phecode
694.2 Other dyschromia Dermatologic 1.01 0.936 – 1.08 0.855 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 1.11 0.923 – 1.34 0.267 117 1170 all phecode
695 Erythematous conditions Dermatologic 0.962 0.922 – 1 0.0763 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 1.1 0.906 – 1.34 0.332 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 0.954 0.801 – 1.14 0.601 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 0.863 0.649 – 1.15 0.313 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.984 0.781 – 1.24 0.888 73 727 all phecode
695.3 Rosacea Dermatologic 1.13 1.01 – 1.27 0.0394 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 0.912 0.823 – 1.01 0.0814 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.842 0.699 – 1.01 0.0698 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 0.92 0.822 – 1.03 0.146 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 0.987 0.917 – 1.06 0.73 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 0.836 0.729 – 0.958 0.00995 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 0.888 0.703 – 1.12 0.323 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 0.91 0.827 – 1 0.054 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 1.01 0.969 – 1.06 0.586 2252 22509 all phecode
696.4 Psoriasis Dermatologic 1.02 0.975 – 1.06 0.403 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 1 0.954 – 1.05 0.915 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 0.991 0.918 – 1.07 0.826 706 7052 all phecode
697 Sarcoidosis Dermatologic 1.01 0.922 – 1.1 0.884 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 1.05 0.979 – 1.13 0.163 782 7814 all phecode
700 Corns and callosities Dermatologic 0.995 0.883 – 1.12 0.93 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.03 1 – 1.06 0.0381 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 0.801 0.642 – 1 0.0507 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.04 1 – 1.09 0.0463 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.02 0.791 – 1.32 0.86 61 610 all phecode
701.4 Keloid scar Dermatologic 1.04 0.908 – 1.2 0.545 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.08 0.984 – 1.19 0.101 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.23 1 – 1.5 0.0454 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.03 0.998 – 1.06 0.0674 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 1.03 0.986 – 1.07 0.199 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 1.03 0.994 – 1.07 0.099 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 1.04 0.934 – 1.16 0.468 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 1.02 0.956 – 1.09 0.539 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 1.03 0.997 – 1.06 0.0772 5267 52727 all phecode
704.1 Alopecia Dermatologic 1.1 0.919 – 1.31 0.309 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.07 0.856 – 1.34 0.544 76 759 all phecode
705 Disorders of sweat glands Dermatologic 0.976 0.852 – 1.12 0.724 228 2287 all phecode
705.3 Hidradenitis Dermatologic 0.97 0.835 – 1.13 0.694 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 1.02 0.936 – 1.11 0.688 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 1.02 0.994 – 1.04 0.146 8317 83195 all phecode
706.1 Acne Dermatologic 0.953 0.758 – 1.2 0.681 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 1.01 0.992 – 1.04 0.203 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 1.01 0.968 – 1.06 0.561 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 0.984 0.918 – 1.05 0.643 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.992 0.958 – 1.03 0.668 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 0.982 0.897 – 1.08 0.698 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 0.918 0.782 – 1.08 0.296 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.874 0.673 – 1.13 0.312 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.999 0.96 – 1.04 0.945 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.03 0.949 – 1.12 0.469 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 1.06 0.976 – 1.16 0.162 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1 0.868 – 1.16 0.967 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.07 0.964 – 1.18 0.211 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 0.983 0.889 – 1.09 0.735 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 0.935 0.833 – 1.05 0.248 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 0.848 0.671 – 1.07 0.169 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.09 0.918 – 1.29 0.332 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.05 0.813 – 1.35 0.725 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.02 0.987 – 1.05 0.286 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.03 0.994 – 1.06 0.11 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.97 0.922 – 1.02 0.238 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.04 0.864 – 1.26 0.651 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.921 0.847 – 1 0.0515 618 6177 all phecode
716 Other arthropathies Musculoskeletal 0.998 0.988 – 1.01 0.776 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.981 0.948 – 1.02 0.291 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.994 0.978 – 1.01 0.479 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 0.998 0.987 – 1.01 0.767 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.967 0.91 – 1.03 0.288 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 1 0.969 – 1.04 0.867 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1.01 0.982 – 1.03 0.636 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.01 0.977 – 1.04 0.675 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.13 0.979 – 1.31 0.0942 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 0.972 0.87 – 1.09 0.618 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 1 0.983 – 1.03 0.688 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.967 0.884 – 1.06 0.47 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.03 0.992 – 1.07 0.127 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.04 0.818 – 1.32 0.751 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.988 0.958 – 1.02 0.447 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 0.981 0.896 – 1.07 0.684 517 5173 all phecode
723.1 Torticollis Musculoskeletal 0.971 0.798 – 1.18 0.771 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 0.997 0.953 – 1.04 0.91 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 0.986 0.89 – 1.09 0.787 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 0.979 0.884 – 1.08 0.681 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.14 0.882 – 1.48 0.313 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 0.992 0.942 – 1.04 0.765 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.994 0.977 – 1.01 0.462 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 0.996 0.975 – 1.02 0.69 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 0.932 0.834 – 1.04 0.217 334 3336 all phecode
726.3 Bursitis Musculoskeletal 0.993 0.926 – 1.07 0.856 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.994 0.97 – 1.02 0.612 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.995 0.956 – 1.03 0.788 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 1.1 0.899 – 1.34 0.359 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.985 0.949 – 1.02 0.436 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 0.975 0.895 – 1.06 0.569 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.03 0.923 – 1.15 0.601 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.07 0.906 – 1.27 0.415 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.03 0.997 – 1.07 0.0776 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.02 0.918 – 1.12 0.763 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 1.03 0.998 – 1.07 0.0678 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.03 0.994 – 1.06 0.106 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 0.99 0.964 – 1.02 0.466 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.923 0.864 – 0.985 0.0166 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 0.82 0.666 – 1.01 0.0621 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.987 0.873 – 1.12 0.84 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.958 0.843 – 1.09 0.517 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 1 0.914 – 1.1 0.926 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.06 0.921 – 1.21 0.43 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.874 0.664 – 1.15 0.334 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.02 0.971 – 1.07 0.432 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 1.19 1.07 – 1.34 0.00206 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.01 0.922 – 1.1 0.893 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 1.09 0.913 – 1.31 0.328 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.01 0.952 – 1.07 0.76 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 0.913 0.753 – 1.11 0.359 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 1 0.981 – 1.02 0.877 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 0.907 0.78 – 1.05 0.202 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 0.992 0.964 – 1.02 0.612 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.993 0.947 – 1.04 0.774 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 0.972 0.922 – 1.02 0.289 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1 0.977 – 1.03 0.847 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 1.05 0.996 – 1.1 0.0687 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.02 0.897 – 1.16 0.752 248 2476 all phecode
737 Curvature of spine Musculoskeletal 1 0.944 – 1.07 0.911 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1 0.943 – 1.07 0.885 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.07 1.02 – 1.12 0.00356 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.09 1.03 – 1.15 0.00168 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 0.943 0.858 – 1.04 0.221 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 0.996 0.983 – 1.01 0.494 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.989 0.974 – 1.01 0.186 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.994 0.973 – 1.02 0.588 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.954 0.855 – 1.07 0.406 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.988 0.908 – 1.08 0.781 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1 0.986 – 1.02 0.673 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.993 0.959 – 1.03 0.685 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 0.958 0.78 – 1.18 0.683 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 0.96 0.883 – 1.04 0.334 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 0.929 0.791 – 1.09 0.368 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 0.994 0.942 – 1.05 0.839 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 0.935 0.77 – 1.14 0.496 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 1.33 1.02 – 1.75 0.0369 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.996 0.958 – 1.03 0.832 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 0.989 0.884 – 1.11 0.842 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.961 0.778 – 1.19 0.707 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.06 0.97 – 1.16 0.192 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 0.99 0.945 – 1.04 0.657 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.994 0.971 – 1.02 0.639 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 0.992 0.967 – 1.02 0.544 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.986 0.959 – 1.01 0.328 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1.08 0.987 – 1.18 0.0929 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 1.06 0.972 – 1.16 0.177 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.977 0.909 – 1.05 0.518 815 8144 all phecode
745 Pain in joint Musculoskeletal 0.99 0.967 – 1.01 0.382 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.01 0.972 – 1.05 0.609 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.01 0.971 – 1.05 0.609 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.95 0.872 – 1.04 0.245 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.96 0.836 – 1.1 0.556 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.03 0.98 – 1.08 0.255 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1 0.85 – 1.18 1 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.01 0.759 – 1.35 0.939 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.05 0.937 – 1.18 0.384 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.966 0.893 – 1.04 0.387 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.981 0.876 – 1.1 0.738 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.08 0.937 – 1.25 0.281 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.92 0.824 – 1.03 0.137 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.898 0.78 – 1.03 0.133 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.979 0.813 – 1.18 0.824 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.997 0.946 – 1.05 0.912 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.02 0.941 – 1.1 0.681 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.991 0.901 – 1.09 0.856 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.08 0.94 – 1.23 0.285 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.985 0.917 – 1.06 0.684 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.949 0.858 – 1.05 0.305 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.06 0.943 – 1.18 0.349 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.963 0.86 – 1.08 0.52 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 1.03 0.911 – 1.17 0.612 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 1.06 0.926 – 1.22 0.383 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.795 0.621 – 1.02 0.0703 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.84 0.693 – 1.02 0.0771 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.809 0.631 – 1.04 0.0964 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.16 0.959 – 1.41 0.127 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.97 0.879 – 1.07 0.549 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.995 0.863 – 1.15 0.94 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.958 0.816 – 1.13 0.605 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.963 0.793 – 1.17 0.705 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.01 0.925 – 1.1 0.865 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.06 0.852 – 1.32 0.599 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.963 0.871 – 1.06 0.453 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1 0.847 – 1.18 0.984 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.998 0.768 – 1.3 0.988 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.02 0.887 – 1.18 0.772 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.03 0.833 – 1.28 0.769 96 959 all phecode
760 Back pain Symptoms 0.991 0.971 – 1.01 0.342 11126 111353 all phecode
761 Cervicalgia Symptoms 0.988 0.941 – 1.04 0.625 1791 17901 all phecode
764 Sciatica Symptoms 0.976 0.935 – 1.02 0.253 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.98 0.922 – 1.04 0.523 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 1.05 0.972 – 1.14 0.199 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.02 0.95 – 1.09 0.605 870 8687 all phecode
771.1 Swelling of limb Symptoms 1 0.973 – 1.03 0.862 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 1.05 0.968 – 1.14 0.239 659 6581 all phecode
773 Pain in limb Symptoms 0.995 0.969 – 1.02 0.698 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 0.989 0.846 – 1.16 0.891 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1 0.954 – 1.05 0.969 1870 18715 all phecode
782.3 Edema Symptoms 0.988 0.939 – 1.04 0.643 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 0.906 0.776 – 1.06 0.213 175 1748 all phecode
783 Fever of unknown origin Symptoms 1 0.968 – 1.03 0.998 3911 39105 all phecode
785 Abdominal pain Symptoms 1.01 0.996 – 1.02 0.208 40080 301686 all phecode
788 Syncope and collapse Symptoms 0.995 0.974 – 1.02 0.673 9069 90813 all phecode
789 Nausea and vomiting Symptoms 1 0.986 – 1.02 0.631 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.01 0.858 – 1.2 0.884 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 0.89 0.701 – 1.13 0.338 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 0.996 0.971 – 1.02 0.787 6357 63635 all phecode
791 Gangrene Symptoms 0.988 0.904 – 1.08 0.784 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.974 0.793 – 1.2 0.8 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.902 0.758 – 1.07 0.242 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 0.975 0.896 – 1.06 0.567 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.1 0.917 – 1.32 0.306 120 1198 all phecode
797 Shock Symptoms 0.954 0.807 – 1.13 0.58 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 0.853 0.696 – 1.05 0.128 102 1020 all phecode
798 Malaise and fatigue Symptoms 0.957 0.924 – 0.992 0.0161 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 0.996 0.916 – 1.08 0.918 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 1.02 0.992 – 1.04 0.198 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.02 0.968 – 1.07 0.516 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.925 0.79 – 1.08 0.332 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.01 0.966 – 1.05 0.675 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 1.04 0.964 – 1.12 0.327 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1 0.96 – 1.05 0.878 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 0.991 0.944 – 1.04 0.708 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 1.03 0.95 – 1.11 0.507 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 1 0.98 – 1.03 0.816 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 0.996 0.948 – 1.05 0.878 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.995 0.967 – 1.02 0.736 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.03 0.974 – 1.08 0.319 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 1.01 0.978 – 1.05 0.455 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1 0.946 – 1.06 0.996 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 1 0.93 – 1.08 0.957 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.992 0.937 – 1.05 0.788 1300 12998 all phecode
817 Concussion Injuries & Poisonings 0.903 0.79 – 1.03 0.136 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.937 0.856 – 1.03 0.16 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.03 0.987 – 1.06 0.193 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 1.02 0.972 – 1.07 0.396 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 1.02 0.974 – 1.06 0.434 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 0.986 0.969 – 1 0.0909 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 0.966 0.882 – 1.06 0.466 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 0.964 0.876 – 1.06 0.443 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.02 0.994 – 1.05 0.119 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.06 0.903 – 1.24 0.483 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.07 0.975 – 1.17 0.161 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1 0.954 – 1.05 0.952 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.02 0.963 – 1.08 0.496 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.993 0.957 – 1.03 0.706 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.02 0.982 – 1.06 0.325 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1.01 0.801 – 1.27 0.936 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.01 0.973 – 1.04 0.663 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.08 0.954 – 1.22 0.23 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 1.05 0.908 – 1.21 0.517 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.998 0.96 – 1.04 0.902 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.02 0.89 – 1.18 0.733 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 1.06 0.816 – 1.37 0.665 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 1 0.971 – 1.04 0.837 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.04 0.789 – 1.37 0.776 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.794 0.639 – 0.986 0.0366 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.916 0.783 – 1.07 0.276 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 0.88 0.799 – 0.969 0.0091 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 1.16 1.02 – 1.33 0.0282 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.06 0.906 – 1.23 0.476 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.07 0.914 – 1.26 0.386 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.05 0.994 – 1.11 0.0813 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 0.992 0.962 – 1.02 0.633 4260 42663 all phecode
916 Contusion Injuries & Poisonings 0.986 0.935 – 1.04 0.613 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.957 0.823 – 1.11 0.575 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.991 0.895 – 1.1 0.865 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.955 0.841 – 1.08 0.48 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.982 0.939 – 1.03 0.434 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.986 0.86 – 1.13 0.843 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.992 0.811 – 1.21 0.935 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.05 0.958 – 1.14 0.313 550 5509 all phecode
947 Urticaria Injuries & Poisonings 1.03 0.929 – 1.15 0.538 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 1.01 0.911 – 1.12 0.841 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.03 0.933 – 1.14 0.569 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.07 0.949 – 1.22 0.256 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.01 0.918 – 1.11 0.858 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.12 0.863 – 1.45 0.402 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.01 0.799 – 1.29 0.904 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.01 0.992 – 1.02 0.332 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.01 0.993 – 1.03 0.251 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.03 0.93 – 1.13 0.612 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.986 0.919 – 1.06 0.69 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1 0.9 – 1.11 0.987 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 0.99 0.89 – 1.1 0.857 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.05 0.916 – 1.2 0.482 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.01 0.89 – 1.14 0.91 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.04 0.917 – 1.17 0.561 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.996 0.97 – 1.02 0.75 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.977 0.919 – 1.04 0.459 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.03 0.939 – 1.13 0.521 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.95 – 1.16 0.33 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.04 0.953 – 1.14 0.365 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.01 0.926 – 1.1 0.837 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.01 0.966 – 1.06 0.621 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.06 0.918 – 1.23 0.411 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1 0.883 – 1.13 0.994 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.04 0.83 – 1.3 0.745 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 0.959 0.791 – 1.16 0.672 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.16 0.944 – 1.42 0.159 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.859 0.662 – 1.11 0.251 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.77 0.59 – 1 0.0541 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1 0.874 – 1.15 0.983 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1 0.931 – 1.08 0.905 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.05 0.909 – 1.21 0.526 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 0.783 0.593 – 1.03 0.0844 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.04 0.853 – 1.26 0.718 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.936 0.771 – 1.14 0.504 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.9 0.722 – 1.12 0.346 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 1 0.968 – 1.04 0.839 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.01 0.969 – 1.04 0.776 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 1.01 0.969 – 1.04 0.776 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 1.02 0.994 – 1.04 0.168 8831 88356 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.01 0.973 – 1.05 0.566 2716 27148 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.01 0.933 – 1.1 0.785 653 6528 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 0.967 0.901 – 1.04 0.345 862 8613 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.19 0.899 – 1.59 0.222 55 550 exclusion phecode
010 Tuberculosis Infectious Diseases 0.921 0.785 – 1.08 0.309 166 1654 exclusion phecode
038 Septicemia Infectious Diseases 0.996 0.965 – 1.03 0.806 4170 41740 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 0.978 0.913 – 1.05 0.533 850 8497 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.05 0.961 – 1.15 0.268 494 4974 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 0.986 0.968 – 1 0.147 12000 120270 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.01 0.974 – 1.05 0.583 3122 31321 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.01 0.957 – 1.06 0.793 1636 16418 exclusion phecode
041.4 E. coli Infectious Diseases 0.979 0.941 – 1.02 0.286 2724 27289 exclusion phecode
053 Herpes zoster Infectious Diseases 0.984 0.889 – 1.09 0.749 411 4134 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.18 0.956 – 1.45 0.124 95 949 exclusion phecode
054 Herpes simplex Infectious Diseases 0.973 0.842 – 1.12 0.706 211 2105 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.01 0.925 – 1.09 0.895 590 5913 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 0.925 0.728 – 1.18 0.526 69 690 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.908 0.759 – 1.09 0.296 132 1330 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.05 0.925 – 1.19 0.455 255 2565 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.05 0.925 – 1.18 0.471 276 2765 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 0.899 0.814 – 0.993 0.0364 428 4286 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.922 0.779 – 1.09 0.342 147 1466 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.993 0.824 – 1.2 0.941 117 1167 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.958 0.898 – 1.02 0.202 1001 10030 exclusion phecode
079 Viral infection Infectious Diseases 1.03 0.987 – 1.07 0.191 2768 27666 exclusion phecode
079.1 Varicella infection Infectious Diseases 1.05 0.811 – 1.35 0.725 64 640 exclusion phecode
080 Postoperative infection Infectious Diseases 0.996 0.966 – 1.03 0.783 4463 44735 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.03 0.988 – 1.07 0.159 2469 24744 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.789 0.612 – 1.02 0.0674 70 708 exclusion phecode
1000 Burns Injuries & Poisonings 1 0.918 – 1.09 0.992 578 5793 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 0.968 0.912 – 1.03 0.292 1197 11996 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 0.987 0.96 – 1.02 0.361 5473 54778 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.02 0.912 – 1.15 0.685 300 2991 exclusion phecode
1005 Other symptoms Injuries & Poisonings 0.981 0.929 – 1.04 0.479 1441 14404 exclusion phecode
1006 Crushing injury Injuries & Poisonings 0.977 0.859 – 1.11 0.722 256 2556 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 1.11 0.974 – 1.25 0.119 256 2558 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.01 0.948 – 1.08 0.743 1013 10127 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 1.01 0.989 – 1.03 0.34 8475 84848 exclusion phecode
1010 Other tests Injuries & Poisonings 0.998 0.972 – 1.03 0.883 5929 59470 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.996 0.975 – 1.02 0.709 9139 91518 exclusion phecode
1012 Late effect Injuries & Poisonings 1.2 0.981 – 1.46 0.0774 105 1057 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 0.951 0.847 – 1.07 0.398 314 3166 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.951 0.738 – 1.22 0.697 66 659 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 0.999 0.968 – 1.03 0.97 4221 42259 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 0.988 0.972 – 1 0.15 15872 158891 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.937 0.828 – 1.06 0.299 278 2809 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.951 0.839 – 1.08 0.429 272 2750 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.858 0.675 – 1.09 0.213 74 756 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.01 0.85 – 1.2 0.913 140 1410 exclusion phecode
112 Candidiasis Infectious Diseases 1.01 0.966 – 1.06 0.659 2122 21256 exclusion phecode
117 Mycoses Infectious Diseases 0.99 0.874 – 1.12 0.88 270 2717 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.04 0.885 – 1.21 0.666 164 1649 exclusion phecode
130 Spirochetal infection Infectious Diseases 1.3 1.04 – 1.62 0.0189 80 800 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 1.06 0.836 – 1.35 0.616 69 688 exclusion phecode
134 Helminthiases Infectious Diseases 1.11 0.924 – 1.33 0.263 127 1267 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.18 0.965 – 1.44 0.107 106 1057 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.12 0.974 – 1.3 0.111 205 2047 exclusion phecode
145 Cancer of mouth Neoplasms 0.981 0.904 – 1.06 0.646 639 6411 exclusion phecode
145.2 Cancer of tongue Neoplasms 0.958 0.852 – 1.08 0.468 309 3094 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 1.05 0.867 – 1.28 0.602 105 1049 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 0.931 0.706 – 1.23 0.611 54 537 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.03 0.951 – 1.12 0.443 628 6337 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.07 0.943 – 1.22 0.291 252 2516 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.03 0.907 – 1.17 0.659 258 2640 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.12 0.855 – 1.48 0.403 57 570 exclusion phecode
150 Cancer of esophagus Neoplasms 1.03 0.953 – 1.11 0.492 761 7625 exclusion phecode
151 Cancer of stomach Neoplasms 0.986 0.905 – 1.08 0.756 568 5690 exclusion phecode
153 Colorectal cancer Neoplasms 1.01 0.975 – 1.04 0.736 4573 45754 exclusion phecode
153.2 Colon cancer Neoplasms 1 0.969 – 1.04 0.795 3098 31016 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.02 0.973 – 1.06 0.462 2163 21616 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.07 0.969 – 1.19 0.174 400 4003 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.03 0.879 – 1.21 0.711 158 1579 exclusion phecode
157 Pancreatic cancer Neoplasms 1.01 0.929 – 1.09 0.868 659 6579 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.02 0.955 – 1.08 0.59 1062 10630 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.995 0.968 – 1.02 0.74 5556 55650 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.09 0.935 – 1.26 0.281 190 1899 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.919 0.796 – 1.06 0.255 205 2046 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.899 0.774 – 1.04 0.164 192 1924 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 1.01 0.781 – 1.3 0.945 60 599 exclusion phecode
165 Cancer within the respiratory system Neoplasms 0.977 0.94 – 1.02 0.237 2817 28219 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 0.987 0.945 – 1.03 0.562 2226 22295 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 1.02 0.923 – 1.12 0.717 435 4360 exclusion phecode
170.1 Bone cancer Neoplasms 1.18 0.986 – 1.4 0.0706 131 1309 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 0.967 0.864 – 1.08 0.564 329 3299 exclusion phecode
172 Skin cancer Neoplasms 0.998 0.98 – 1.02 0.819 13476 134871 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.998 0.959 – 1.04 0.937 2675 26769 exclusion phecode
172.11 Melanomas of skin Neoplasms 1 0.961 – 1.04 0.987 2707 27089 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.996 0.977 – 1.02 0.712 10986 109963 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.971 0.896 – 1.05 0.472 666 6654 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.919 0.788 – 1.07 0.284 179 1814 exclusion phecode
174 Breast cancer Neoplasms 1.01 0.991 – 1.03 0.345 12658 126459 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1.01 0.99 – 1.03 0.361 12449 124369 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.01 0.992 – 1.03 0.27 11732 117375 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.07 0.888 – 1.3 0.469 115 1148 exclusion phecode
175 Acquired absence of breast Neoplasms 1.04 0.997 – 1.08 0.0676 2392 23985 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 0.996 0.953 – 1.04 0.855 2173 21726 exclusion phecode
180.1 Cervical cancer Neoplasms 0.987 0.872 – 1.12 0.829 272 2716 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.998 0.954 – 1.04 0.927 2075 20766 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 1.04 0.982 – 1.1 0.177 1282 12824 exclusion phecode
184 Cancer of other female genital organs Neoplasms 0.985 0.932 – 1.04 0.598 1377 13760 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.01 0.95 – 1.08 0.669 966 9657 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.01 0.943 – 1.08 0.803 938 9377 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.896 0.797 – 1.01 0.0683 305 3044 exclusion phecode
185 Cancer of prostate Neoplasms 1 0.973 – 1.03 0.977 5971 58776 exclusion phecode
187 Cancer of other male genital organs Neoplasms 1.05 0.95 – 1.15 0.359 449 4482 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.2 0.938 – 1.52 0.15 70 700 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 1.01 0.898 – 1.14 0.842 287 2866 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.11 0.918 – 1.34 0.287 110 1097 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.02 0.988 – 1.05 0.229 4154 41581 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.996 0.935 – 1.06 0.907 1071 10717 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.988 0.926 – 1.05 0.717 1031 10318 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.23 0.954 – 1.58 0.111 66 660 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.02 0.982 – 1.07 0.274 2406 24096 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.02 0.975 – 1.07 0.393 2139 21431 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1 0.849 – 1.19 0.954 144 1439 exclusion phecode
190 Cancer of eye Neoplasms 0.938 0.804 – 1.09 0.41 176 1756 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.02 0.945 – 1.1 0.591 688 6877 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 1.01 0.925 – 1.1 0.862 565 5648 exclusion phecode
191.11 Cancer of brain Neoplasms 1.01 0.926 – 1.11 0.796 524 5237 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.01 0.815 – 1.25 0.935 94 949 exclusion phecode
195 Cancer, suspected or other Neoplasms 0.999 0.983 – 1.02 0.917 16833 165386 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1 0.984 – 1.02 0.967 16134 159424 exclusion phecode
197 Chemotherapy Neoplasms 1.02 1.01 – 1.04 0.00389 21390 213097 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.02 0.996 – 1.04 0.118 9493 95450 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.02 0.996 – 1.05 0.0878 5323 53639 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.06 1.01 – 1.1 0.0128 2249 22661 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.02 0.966 – 1.07 0.516 1549 15488 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.01 0.974 – 1.05 0.506 2661 26635 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1 0.932 – 1.07 0.997 845 8469 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.02 0.977 – 1.07 0.357 2151 21589 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.883 0.757 – 1.03 0.11 184 1889 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.02 0.97 – 1.08 0.397 1424 14308 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.18 0.957 – 1.44 0.124 94 950 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.04 0.979 – 1.11 0.192 990 9905 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.09 0.985 – 1.21 0.0954 386 3867 exclusion phecode
201 Hodgkin's disease Neoplasms 1.03 0.909 – 1.17 0.639 257 2595 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.976 0.934 – 1.02 0.261 2251 22692 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.964 0.919 – 1.01 0.138 1798 18062 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.1 0.989 – 1.22 0.0778 362 3645 exclusion phecode
202.24 Large cell lymphoma Neoplasms 0.961 0.882 – 1.05 0.357 579 5820 exclusion phecode
204 Leukemia Neoplasms 1 0.954 – 1.05 0.907 1656 16621 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1.02 0.942 – 1.12 0.57 575 5780 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.939 0.712 – 1.24 0.657 56 558 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.04 0.95 – 1.14 0.39 506 5078 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.03 0.939 – 1.13 0.511 462 4616 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 1.05 0.944 – 1.18 0.353 329 3285 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.05 0.884 – 1.24 0.591 144 1440 exclusion phecode
204.4 Multiple myeloma Neoplasms 0.924 0.845 – 1.01 0.0788 553 5557 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1.01 0.991 – 1.02 0.417 19841 191714 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.9 0.842 – 0.962 0.00204 976 9776 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.03 1 – 1.06 0.0308 5239 52407 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.04 0.928 – 1.16 0.533 344 3465 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.06 0.947 – 1.19 0.306 316 3182 exclusion phecode
214 Lipoma Neoplasms 0.979 0.954 – 1.01 0.119 6218 62306 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.977 0.948 – 1.01 0.141 4572 45843 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.97 0.911 – 1.03 0.334 1107 11052 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.992 0.968 – 1.02 0.478 7653 76583 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.06 0.98 – 1.15 0.139 631 6306 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 1.09 1.01 – 1.19 0.0329 594 5937 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 1 0.979 – 1.02 0.973 10005 100076 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 1 0.984 – 1.02 0.698 10223 102245 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.945 0.848 – 1.05 0.301 355 3547 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.912 0.863 – 0.963 0.00101 1442 14461 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.04 0.901 – 1.19 0.625 219 2195 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.847 0.72 – 0.998 0.0466 160 1600 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.01 0.871 – 1.18 0.85 173 1729 exclusion phecode
224 Benign neoplasm of eye Neoplasms 1.02 0.852 – 1.22 0.834 129 1296 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.11 0.874 – 1.42 0.381 67 680 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.03 0.962 – 1.11 0.368 815 8148 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.04 0.967 – 1.12 0.296 774 7749 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.915 0.702 – 1.19 0.513 59 589 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.16 1.02 – 1.31 0.0209 253 2664 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.02 0.952 – 1.1 0.556 854 8635 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.94 0.808 – 1.09 0.419 185 1857 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.05 0.944 – 1.17 0.362 365 3709 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.04 0.929 – 1.17 0.486 309 3114 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.959 0.91 – 1.01 0.11 1593 15949 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.01 0.966 – 1.05 0.715 2393 23936 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.02 0.941 – 1.11 0.581 564 6010 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.947 0.888 – 1.01 0.0906 1058 11089 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.12 1.02 – 1.23 0.017 449 4704 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.851 0.783 – 0.925 0.000143 648 6783 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.992 0.946 – 1.04 0.754 1845 18523 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.965 0.877 – 1.06 0.464 453 4551 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.12 0.912 – 1.38 0.274 90 910 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 1 0.843 – 1.2 0.965 138 1379 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 0.896 0.881 – 0.912 5.59e-35 14455 144994 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.02 0.956 – 1.09 0.546 1007 11075 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.728 0.586 – 0.904 0.00414 100 1010 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.889 0.873 – 0.905 2.66e-38 13869 138868 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.993 0.875 – 1.13 0.908 264 2877 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.997 0.864 – 1.15 0.964 198 2177 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.01 0.875 – 1.17 0.854 190 2096 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 0.871 0.784 – 0.968 0.0106 379 3974 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.01 0.998 – 1.03 0.0996 19753 185872 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.05 1.01 – 1.09 0.0208 2756 27601 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.955 0.838 – 1.09 0.487 239 2386 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.13 0.89 – 1.43 0.321 76 770 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.02 0.927 – 1.12 0.692 473 4743 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.04 0.882 – 1.22 0.671 160 1609 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.01 0.998 – 1.03 0.0926 17798 170083 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.917 0.741 – 1.13 0.421 104 1050 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.99 0.856 – 1.15 0.898 200 2018 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.981 0.918 – 1.05 0.582 983 9902 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.09 0.998 – 1.2 0.0554 503 5063 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.07 0.987 – 1.15 0.105 679 6822 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.06 0.936 – 1.2 0.365 265 2655 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.08 0.978 – 1.19 0.126 415 4177 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.991 0.833 – 1.18 0.921 131 1308 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.07 0.966 – 1.2 0.186 349 3495 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1 0.948 – 1.06 0.901 1326 13330 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.04 0.974 – 1.11 0.23 931 9364 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.01 0.943 – 1.09 0.743 855 8711 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.01 0.935 – 1.08 0.852 770 7795 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.07 0.894 – 1.27 0.479 132 1417 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.937 0.865 – 1.01 0.106 680 6815 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.07 0.92 – 1.25 0.381 187 1864 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.09 0.882 – 1.34 0.438 95 946 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.838 0.738 – 0.953 0.00683 260 2615 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.791 0.635 – 0.987 0.0377 92 918 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.02 0.873 – 1.19 0.791 158 1576 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.995 0.917 – 1.08 0.901 636 6368 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.05 0.902 – 1.22 0.532 180 1796 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.05 0.855 – 1.28 0.657 103 1028 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.06 0.842 – 1.32 0.641 76 759 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.931 0.835 – 1.04 0.193 361 3611 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.927 0.831 – 1.03 0.17 360 3601 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.876 0.762 – 1.01 0.0627 240 2396 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.864 0.744 – 1 0.0543 209 2087 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 0.86 0.728 – 1.02 0.0769 160 1619 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.859 0.724 – 1.02 0.0794 152 1539 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.04 0.85 – 1.27 0.708 101 1020 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.806 0.677 – 0.959 0.0152 149 1496 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.976 0.848 – 1.12 0.74 202 2017 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.04 0.786 – 1.37 0.79 51 509 exclusion phecode
260.6 Anorexia Endocrine/metabolic 0.971 0.904 – 1.04 0.42 830 8311 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.04 0.978 – 1.1 0.221 1192 11961 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.04 0.967 – 1.12 0.277 754 7533 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.05 0.951 – 1.15 0.35 441 4458 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.08 0.846 – 1.37 0.551 71 768 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.02 0.891 – 1.16 0.799 241 2404 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.01 0.904 – 1.13 0.847 338 3374 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.907 0.806 – 1.02 0.107 302 3023 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.946 0.834 – 1.07 0.392 260 2603 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.04 0.898 – 1.2 0.606 190 1906 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1.06 0.875 – 1.28 0.56 113 1128 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.74 0.57 – 0.96 0.0235 69 687 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.26 1.07 – 1.49 0.00581 160 1597 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.33 1.11 – 1.59 0.00162 139 1389 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1 0.993 – 1.02 0.476 34798 235238 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1 0.993 – 1.02 0.471 34727 235008 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1 0.991 – 1.01 0.659 32287 227898 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.688 0.518 – 0.912 0.00942 58 580 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.06 0.904 – 1.24 0.481 164 1636 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.957 0.834 – 1.1 0.53 211 2109 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.02 0.986 – 1.05 0.264 3718 37210 exclusion phecode
274.1 Gout Endocrine/metabolic 1.02 0.98 – 1.05 0.373 3166 31691 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.1 0.91 – 1.33 0.327 112 1119 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.03 0.947 – 1.11 0.518 612 6118 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.02 0.937 – 1.11 0.632 557 5572 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.02 0.979 – 1.07 0.3 2084 21054 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.981 0.905 – 1.06 0.632 652 6533 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.04 0.939 – 1.16 0.423 373 3745 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.04 0.976 – 1.1 0.245 1182 12007 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.987 0.843 – 1.15 0.868 171 1715 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.02 0.994 – 1.04 0.147 7266 72875 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.04 1.01 – 1.07 0.0231 4074 40900 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.918 0.802 – 1.05 0.218 237 2407 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.02 0.97 – 1.07 0.485 1816 18182 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.02 0.951 – 1.09 0.628 967 9722 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.07 1.02 – 1.13 0.00918 1419 14226 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.96 0.903 – 1.02 0.192 1157 11618 exclusion phecode
276.41 Acidosis Endocrine/metabolic 0.956 0.896 – 1.02 0.166 1052 10566 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 0.976 0.799 – 1.19 0.811 113 1129 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.01 0.976 – 1.06 0.457 2818 28239 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 0.974 0.884 – 1.07 0.596 450 4531 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 0.972 0.815 – 1.16 0.751 128 1276 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.06 0.988 – 1.13 0.109 898 8972 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.01 0.902 – 1.12 0.925 362 3609 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.08 0.941 – 1.23 0.28 229 2296 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.26 0.953 – 1.68 0.104 52 519 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.997 0.978 – 1.02 0.802 10779 108201 exclusion phecode
278.1 Obesity Endocrine/metabolic 0.996 0.977 – 1.02 0.724 10617 106583 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 1.05 0.842 – 1.3 0.677 84 837 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.09 0.855 – 1.39 0.48 66 658 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.05 0.921 – 1.19 0.474 250 2509 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.07 0.926 – 1.23 0.362 209 2099 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.03 0.865 – 1.23 0.73 138 1390 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.05 0.925 – 1.2 0.432 248 2478 exclusion phecode
280 Iron deficiency anemias Hematopoietic 0.99 0.967 – 1.01 0.397 7599 76105 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.993 0.97 – 1.02 0.584 7302 73091 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.938 0.853 – 1.03 0.192 450 4539 exclusion phecode
281 Other deficiency anemia Hematopoietic 0.993 0.934 – 1.06 0.822 1111 11114 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 0.987 0.927 – 1.05 0.695 1065 10658 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.05 0.972 – 1.13 0.226 749 7506 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.874 0.746 – 1.02 0.0967 177 1768 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 0.87 0.744 – 1.02 0.0842 183 1833 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.09 0.833 – 1.43 0.523 54 538 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.01 0.85 – 1.19 0.94 150 1499 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 0.89 0.665 – 1.19 0.437 56 560 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.18 0.955 – 1.45 0.126 85 849 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.25 1.06 – 1.47 0.00949 135 1376 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.2 0.992 – 1.44 0.0607 103 1059 exclusion phecode
284 Aplastic anemia Hematopoietic 1.1 1 – 1.22 0.0484 434 4353 exclusion phecode
285 Other anemias Hematopoietic 1.01 0.992 – 1.03 0.277 12084 120995 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.12 0.988 – 1.27 0.0768 269 2704 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.01 0.935 – 1.09 0.79 696 6975 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.979 0.885 – 1.08 0.684 413 4145 exclusion phecode
286 Coagulation defects Hematopoietic 1.02 0.954 – 1.09 0.563 919 9212 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 1.07 0.969 – 1.17 0.19 458 4591 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 1.12 0.918 – 1.37 0.261 96 959 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.07 0.952 – 1.21 0.251 294 2943 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.06 0.82 – 1.36 0.67 62 629 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.856 0.682 – 1.07 0.179 86 860 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.969 0.873 – 1.08 0.555 386 3866 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1 0.953 – 1.05 0.938 1650 16517 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.967 0.803 – 1.16 0.724 129 1290 exclusion phecode
287.2 Allergic purpura Hematopoietic 0.99 0.753 – 1.3 0.94 51 510 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 0.999 0.948 – 1.05 0.973 1551 15529 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1 0.908 – 1.11 0.941 418 4190 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.01 0.795 – 1.29 0.909 75 749 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.01 0.975 – 1.04 0.647 3757 37642 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.01 0.971 – 1.04 0.718 3162 31677 exclusion phecode
288.11 Neutropenia Hematopoietic 1.01 0.972 – 1.05 0.659 3170 31757 exclusion phecode
288.3 Eosinophilia Hematopoietic 1.03 0.82 – 1.29 0.801 71 709 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.06 0.985 – 1.13 0.126 859 8621 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.05 0.93 – 1.18 0.445 290 2896 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.01 0.97 – 1.05 0.62 2587 26036 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1 0.915 – 1.09 0.994 516 5149 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 0.99 0.879 – 1.12 0.871 292 2914 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.11 0.901 – 1.38 0.318 90 899 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.976 0.931 – 1.02 0.307 1927 19270 exclusion phecode
290.1 Dementias Mental Disorders 0.99 0.928 – 1.06 0.764 1004 10027 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 1.03 0.931 – 1.13 0.586 431 4302 exclusion phecode
290.16 Vascular dementia Mental Disorders 0.898 0.774 – 1.04 0.157 201 2007 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.976 0.9 – 1.06 0.546 649 6499 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.03 0.813 – 1.32 0.78 70 709 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.997 0.928 – 1.07 0.931 834 8377 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.04 0.871 – 1.23 0.691 132 1319 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.949 0.839 – 1.07 0.41 286 2865 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.02 0.925 – 1.12 0.701 434 4372 exclusion phecode
292 Neurological disorders Mental Disorders 0.983 0.953 – 1.01 0.261 4613 46223 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.997 0.945 – 1.05 0.913 1504 15063 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.967 0.834 – 1.12 0.652 190 1906 exclusion phecode
292.3 Memory loss Mental Disorders 1.03 0.955 – 1.12 0.419 695 6971 exclusion phecode
292.4 Altered mental status Mental Disorders 0.979 0.937 – 1.02 0.351 2175 21812 exclusion phecode
292.6 Hallucinations Mental Disorders 1.03 0.919 – 1.16 0.589 306 3069 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 0.997 0.953 – 1.04 0.912 2078 20767 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.94 0.878 – 1.01 0.0809 889 9002 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.03 0.958 – 1.1 0.437 840 8444 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.03 0.951 – 1.13 0.434 573 5766 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.09 0.938 – 1.27 0.254 178 1779 exclusion phecode
295.3 Psychosis Mental Disorders 0.978 0.837 – 1.14 0.778 169 1708 exclusion phecode
296 Mood disorders Mental Disorders 0.993 0.975 – 1.01 0.447 12353 123720 exclusion phecode
296.1 Bipolar Mental Disorders 0.993 0.933 – 1.06 0.832 1058 10591 exclusion phecode
296.2 Depression Mental Disorders 0.993 0.974 – 1.01 0.445 11719 117374 exclusion phecode
296.22 Major depressive disorder Mental Disorders 0.961 0.863 – 1.07 0.474 361 3600 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.999 0.891 – 1.12 0.991 311 3068 exclusion phecode
300 Anxiety disorders Mental Disorders 1.01 0.982 – 1.03 0.581 6836 68420 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.01 0.982 – 1.03 0.556 6316 63218 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 1.08 0.915 – 1.27 0.374 149 1496 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.01 0.931 – 1.09 0.878 707 7063 exclusion phecode
300.13 Phobia Mental Disorders 1.03 0.939 – 1.13 0.535 501 5007 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.938 0.785 – 1.12 0.476 140 1407 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 0.839 0.637 – 1.11 0.212 53 530 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.17 0.976 – 1.4 0.0891 124 1236 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.09 0.9 – 1.31 0.392 112 1129 exclusion phecode
301 Personality disorders Mental Disorders 1.1 0.985 – 1.23 0.0914 334 3334 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.22 1.01 – 1.46 0.0366 119 1185 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 0.899 0.794 – 1.02 0.0899 283 2842 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.06 0.968 – 1.17 0.203 467 4677 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 1.02 0.912 – 1.14 0.742 350 3507 exclusion phecode
303.4 Somatoform disorder Mental Disorders 1.27 1.06 – 1.51 0.00932 123 1229 exclusion phecode
304 Adjustment reaction Mental Disorders 1.04 0.919 – 1.17 0.571 293 2935 exclusion phecode
305.2 Eating disorder Mental Disorders 1.03 0.83 – 1.28 0.788 90 897 exclusion phecode
306 Other mental disorder Mental Disorders 0.989 0.977 – 1 0.0876 28011 229924 exclusion phecode
306.9 Tension headache Mental Disorders 1.04 0.927 – 1.16 0.518 315 3146 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 1.1 0.87 – 1.39 0.422 76 769 exclusion phecode
313.3 Autism Mental Disorders 1.23 0.935 – 1.61 0.14 53 539 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.03 0.925 – 1.15 0.575 351 3513 exclusion phecode
315.1 Learning disorder Mental Disorders 0.977 0.831 – 1.15 0.782 161 1610 exclusion phecode
315.2 Speech and language disorder Mental Disorders 1.08 0.871 – 1.33 0.495 88 878 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.01 0.986 – 1.04 0.32 5308 53092 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.99 0.766 – 1.28 0.938 60 598 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.01 0.987 – 1.02 0.586 12682 126797 exclusion phecode
317.1 Alcoholism Mental Disorders 1.01 0.988 – 1.03 0.357 8878 88854 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 0.988 0.92 – 1.06 0.728 837 8385 exclusion phecode
318 Tobacco use disorder Mental Disorders 0.99 0.976 – 1.01 0.2 19332 185309 exclusion phecode
320 Meningitis Neurological 0.991 0.899 – 1.09 0.861 444 4444 exclusion phecode
323 Encephalitis Neurological 0.995 0.889 – 1.11 0.931 342 3420 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 0.917 0.717 – 1.17 0.487 74 738 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 0.949 0.84 – 1.07 0.399 292 2912 exclusion phecode
327 Sleep disorders Neurological 0.939 0.883 – 0.998 0.0424 1164 11648 exclusion phecode
327.3 Sleep apnea Neurological 0.994 0.964 – 1.03 0.711 4421 44288 exclusion phecode
327.4 Insomnia Neurological 0.951 0.806 – 1.12 0.551 163 1660 exclusion phecode
327.41 Organic or persistent insomnia Neurological 0.963 0.805 – 1.15 0.684 136 1390 exclusion phecode
331 Other cerebral degenerations Neurological 1.02 0.958 – 1.08 0.561 1140 11408 exclusion phecode
331.1 Hydrocephalus Neurological 1.05 0.956 – 1.15 0.323 502 5007 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.02 0.926 – 1.13 0.65 430 4297 exclusion phecode
332 Parkinson's disease Neurological 0.945 0.889 – 1.01 0.0729 1124 11250 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.964 0.899 – 1.03 0.309 893 8943 exclusion phecode
333.1 Essential tremor Neurological 0.958 0.83 – 1.11 0.56 216 2154 exclusion phecode
333.2 Myoclonus Neurological 0.993 0.808 – 1.22 0.95 96 956 exclusion phecode
333.4 Torsion dystonia Neurological 1.02 0.898 – 1.16 0.752 252 2527 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 0.997 0.95 – 1.05 0.908 1807 18110 exclusion phecode
334.1 Spinocerebellar disease Neurological 0.957 0.788 – 1.16 0.661 116 1167 exclusion phecode
334.2 Anterior horn cell disease Neurological 1.04 0.91 – 1.18 0.597 245 2446 exclusion phecode
335 Multiple sclerosis Neurological 1 0.95 – 1.06 0.87 1339 13370 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.02 0.895 – 1.15 0.814 266 2666 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.14 0.903 – 1.44 0.273 72 718 exclusion phecode
338 Pain Neurological 1.06 0.98 – 1.14 0.155 766 7683 exclusion phecode
338.1 Acute pain Neurological 1.06 0.954 – 1.17 0.295 393 3931 exclusion phecode
338.2 Chronic pain Neurological 1.02 0.922 – 1.14 0.651 379 3811 exclusion phecode
339 Other headache syndromes Neurological 0.992 0.969 – 1.02 0.487 7811 78179 exclusion phecode
340 Migraine Neurological 1.01 0.97 – 1.05 0.697 2857 28577 exclusion phecode
340.1 Migrain with aura Neurological 0.993 0.859 – 1.15 0.928 212 2115 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.01 0.888 – 1.14 0.906 251 2532 exclusion phecode
342 Hemiplegia Neurological 0.934 0.884 – 0.986 0.0131 1490 14935 exclusion phecode
343 Infantile cerebral palsy Neurological 0.881 0.737 – 1.05 0.161 145 1448 exclusion phecode
344 Other paralytic syndromes Neurological 1.04 0.963 – 1.13 0.299 654 6588 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.01 0.977 – 1.03 0.714 5016 50219 exclusion phecode
345.1 Epilepsy Neurological 1.03 0.958 – 1.1 0.46 865 8653 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.02 0.927 – 1.12 0.673 438 4381 exclusion phecode
345.12 Partial epilepsy Neurological 1.02 0.901 – 1.15 0.787 277 2776 exclusion phecode
345.3 Convulsions Neurological 1.03 0.983 – 1.07 0.246 2231 22319 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.888 0.75 – 1.05 0.169 143 1438 exclusion phecode
348 Other conditions of brain Neurological 1 0.933 – 1.08 0.903 777 7803 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 0.995 0.876 – 1.13 0.941 267 2678 exclusion phecode
348.4 Cerebral cysts Neurological 0.885 0.736 – 1.06 0.192 133 1348 exclusion phecode
348.7 Coma Neurological 1 0.899 – 1.12 0.983 358 3591 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.06 0.935 – 1.21 0.349 249 2503 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 0.98 0.884 – 1.09 0.7 390 3896 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.08 0.971 – 1.21 0.152 341 3412 exclusion phecode
350 Abnormal movement Neurological 0.983 0.944 – 1.02 0.399 2660 26702 exclusion phecode
350.1 Abnormal involuntary movements Neurological 0.988 0.921 – 1.06 0.729 885 8845 exclusion phecode
350.2 Abnormality of gait Neurological 0.981 0.931 – 1.03 0.455 1588 15953 exclusion phecode
350.3 Lack of coordination Neurological 0.952 0.854 – 1.06 0.371 360 3637 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.933 0.71 – 1.22 0.615 54 538 exclusion phecode
351 Other peripheral nerve disorders Neurological 0.998 0.979 – 1.02 0.793 12403 124207 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.01 0.96 – 1.07 0.605 1365 13692 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.956 0.868 – 1.05 0.354 462 4635 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.03 0.965 – 1.11 0.347 876 8786 exclusion phecode
353 Nerve root and plexus disorders Neurological 1 0.942 – 1.06 0.986 1128 11306 exclusion phecode
353.1 Nerve plexus lesions Neurological 1.03 0.852 – 1.25 0.738 114 1137 exclusion phecode
353.2 Nerve root lesions Neurological 1.03 0.79 – 1.34 0.825 57 570 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.08 0.916 – 1.27 0.362 152 1517 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.06 0.999 – 1.12 0.0529 1358 13634 exclusion phecode
358 Myoneural disorders Neurological 0.903 0.783 – 1.04 0.157 211 2107 exclusion phecode
358.1 Myasthenia gravis Neurological 0.945 0.815 – 1.1 0.455 192 1916 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 1.05 0.95 – 1.15 0.357 464 4644 exclusion phecode
359.1 Muscular dystrophies Neurological 0.996 0.825 – 1.2 0.964 122 1216 exclusion phecode
359.2 Myopathy Neurological 1.08 0.972 – 1.21 0.145 359 3596 exclusion phecode
360 Disorders of the globe Sense Organs 0.998 0.892 – 1.12 0.968 337 3363 exclusion phecode
360.2 Progressive myopia Sense Organs 1.01 0.889 – 1.15 0.844 251 2505 exclusion phecode
361 Retinal detachments and defects Sense Organs 1 0.967 – 1.04 0.862 3244 32426 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.983 0.93 – 1.04 0.553 1388 13870 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.78 0.604 – 1.01 0.056 68 679 exclusion phecode
362 Other retinal disorders Sense Organs 0.982 0.95 – 1.02 0.292 3831 38339 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.02 0.971 – 1.06 0.499 2179 21791 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.01 0.97 – 1.06 0.551 2176 21761 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1 0.853 – 1.18 0.985 161 1607 exclusion phecode
362.31 Separation of retinal layers Sense Organs 0.938 0.768 – 1.15 0.529 99 989 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.954 0.888 – 1.03 0.199 847 8475 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.936 0.8 – 1.09 0.406 182 1827 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.927 0.737 – 1.17 0.52 82 810 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.01 0.83 – 1.22 0.951 116 1158 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.964 0.825 – 1.13 0.646 170 1697 exclusion phecode
363.3 Chorioretinal scars Sense Organs 1.18 0.929 – 1.49 0.176 69 690 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.04 0.959 – 1.13 0.351 647 6476 exclusion phecode
364.1 Corneal opacity Sense Organs 0.974 0.793 – 1.2 0.804 90 907 exclusion phecode
364.2 Corneal edema Sense Organs 0.825 0.655 – 1.04 0.104 79 797 exclusion phecode
364.4 Corneal degenerations Sense Organs 1.07 0.926 – 1.23 0.365 201 2015 exclusion phecode
364.41 Keratoconus Sense Organs 1.04 0.834 – 1.3 0.728 86 868 exclusion phecode
364.5 Corneal dystrophy Sense Organs 1.09 0.942 – 1.25 0.256 211 2108 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 1.07 0.871 – 1.31 0.525 100 997 exclusion phecode
365 Glaucoma Sense Organs 0.979 0.949 – 1.01 0.192 4403 44088 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 1.04 0.979 – 1.11 0.188 1032 10337 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 1.04 0.978 – 1.11 0.204 1026 10278 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.995 0.92 – 1.08 0.898 698 6990 exclusion phecode
366 Cataract Sense Organs 1.01 0.992 – 1.02 0.393 19906 168568 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.926 0.73 – 1.17 0.527 68 700 exclusion phecode
366.2 Senile cataract Sense Organs 1.02 0.993 – 1.04 0.185 8221 81833 exclusion phecode
366.3 Traumatic cataract Sense Organs 1.11 0.908 – 1.36 0.309 102 1019 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.02 0.977 – 1.06 0.375 2405 24074 exclusion phecode
367.1 Myopia Sense Organs 1.02 0.96 – 1.08 0.548 1249 12508 exclusion phecode
367.2 Astigmatism Sense Organs 1.05 0.902 – 1.21 0.549 190 1899 exclusion phecode
367.8 Hypermetropia Sense Organs 1 0.882 – 1.14 0.969 252 2528 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.01 0.938 – 1.09 0.758 719 7194 exclusion phecode
368 Visual disturbances Sense Organs 0.971 0.935 – 1.01 0.134 2959 29621 exclusion phecode
368.1 Amblyopia Sense Organs 0.94 0.859 – 1.03 0.182 532 5314 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.958 0.888 – 1.03 0.274 723 7281 exclusion phecode
368.3 Anisometropia Sense Organs 1.21 1.03 – 1.43 0.0199 154 1547 exclusion phecode
368.4 Visual field defects Sense Organs 0.968 0.865 – 1.08 0.574 332 3324 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.957 0.881 – 1.04 0.302 612 6111 exclusion phecode
369 Infection of the eye Sense Organs 1.02 0.939 – 1.12 0.584 553 5541 exclusion phecode
369.2 Eye infection, viral Sense Organs 1.01 0.843 – 1.21 0.917 125 1255 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.978 0.851 – 1.12 0.751 213 2128 exclusion phecode
370 Keratitis Sense Organs 0.978 0.868 – 1.1 0.722 286 2851 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.925 0.779 – 1.1 0.378 141 1408 exclusion phecode
371 Inflammation of the eye Sense Organs 0.969 0.934 – 1.01 0.102 3041 30462 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.855 0.777 – 0.94 0.00125 481 4816 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.987 0.946 – 1.03 0.542 2350 23542 exclusion phecode
372 Disorders of conjunctiva Sense Organs 0.983 0.912 – 1.06 0.654 760 7596 exclusion phecode
374 Other disorders of eyelids Sense Organs 1.01 0.985 – 1.04 0.366 5674 56753 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.973 0.914 – 1.04 0.394 1062 10638 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 1.03 0.984 – 1.08 0.189 1823 18209 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.99 0.948 – 1.03 0.654 2199 22010 exclusion phecode
375.2 Epiphora Sense Organs 1.01 0.941 – 1.08 0.824 897 8961 exclusion phecode
376 Disorders of the orbit Sense Organs 0.802 0.638 – 1.01 0.0584 86 858 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.981 0.879 – 1.09 0.728 360 3613 exclusion phecode
377.1 Optic atrophy Sense Organs 0.86 0.644 – 1.15 0.304 56 569 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.991 0.826 – 1.19 0.921 124 1249 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.957 0.905 – 1.01 0.12 1406 14105 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.943 0.88 – 1.01 0.0934 907 9077 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.01 0.88 – 1.16 0.88 212 2137 exclusion phecode
378.5 Paralytic strabismus Sense Organs 0.927 0.818 – 1.05 0.232 274 2752 exclusion phecode
379 Other disorders of eye Sense Organs 1 0.969 – 1.04 0.898 3699 37031 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 1.02 0.965 – 1.08 0.497 1365 13659 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 1 0.957 – 1.05 0.87 1812 18116 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.15 0.898 – 1.46 0.274 71 710 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.875 0.788 – 0.972 0.0128 400 4023 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.01 0.861 – 1.18 0.909 169 1687 exclusion phecode
380 Disorders of external ear Sense Organs 0.997 0.921 – 1.08 0.949 641 6406 exclusion phecode
380.1 Otitis externa Sense Organs 0.924 0.845 – 1.01 0.0839 509 5098 exclusion phecode
380.4 Impacted cerumen Sense Organs 1.06 0.949 – 1.17 0.319 362 3608 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.975 0.933 – 1.02 0.276 2149 21480 exclusion phecode
381.1 Otitis media Sense Organs 0.97 0.924 – 1.02 0.228 1766 17657 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.948 0.883 – 1.02 0.137 852 8517 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 1 0.862 – 1.16 0.998 193 1927 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.941 0.806 – 1.1 0.441 171 1708 exclusion phecode
381.9 Otorrhea Sense Organs 0.958 0.847 – 1.08 0.497 281 2804 exclusion phecode
382 Otalgia Sense Organs 1.01 0.902 – 1.13 0.849 307 3081 exclusion phecode
383 Otosclerosis Sense Organs 0.915 0.812 – 1.03 0.145 309 3086 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 0.968 0.915 – 1.02 0.262 1299 12976 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 0.967 0.908 – 1.03 0.296 1042 10422 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.992 0.921 – 1.07 0.821 783 7831 exclusion phecode
385.3 Cholesteatoma Sense Organs 1.02 0.937 – 1.11 0.67 607 6074 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.01 0.884 – 1.16 0.867 241 2407 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.978 0.93 – 1.03 0.379 1734 17357 exclusion phecode
386.1 Meniere's disease Sense Organs 0.998 0.915 – 1.09 0.956 576 5763 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.95 0.853 – 1.06 0.35 376 3755 exclusion phecode
386.3 Labyrinthitis Sense Organs 0.98 0.909 – 1.06 0.596 764 7659 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.979 0.949 – 1.01 0.167 4580 45762 exclusion phecode
388 Other disorders of ear Sense Organs 0.972 0.841 – 1.12 0.696 202 2016 exclusion phecode
389 Hearing loss Sense Organs 0.994 0.963 – 1.03 0.705 4180 41900 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 1.03 0.933 – 1.13 0.604 455 4552 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.04 0.942 – 1.14 0.459 449 4493 exclusion phecode
389.4 Tinnitus Sense Organs 0.916 0.836 – 1 0.0631 512 5130 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.01 0.976 – 1.04 0.722 4893 48934 exclusion phecode
394.2 Mitral valve disease Circulatory System 0.991 0.955 – 1.03 0.648 2989 29898 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.01 0.952 – 1.07 0.786 1280 12802 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 0.988 0.927 – 1.05 0.705 1058 10559 exclusion phecode
395 Heart valve disorders Circulatory System 1 0.972 – 1.04 0.817 4219 42189 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.993 0.955 – 1.03 0.712 2887 28877 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.06 0.94 – 1.2 0.341 276 2766 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 0.994 0.813 – 1.22 0.95 105 1038 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.979 0.798 – 1.2 0.842 97 968 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.04 0.988 – 1.1 0.127 1493 14931 exclusion phecode
396 Abnormal heart sounds Circulatory System 0.998 0.937 – 1.06 0.949 1048 10458 exclusion phecode
401 Hypertension Circulatory System 1.01 0.997 – 1.01 0.182 73861 266757 exclusion phecode
401.1 Essential hypertension Circulatory System 1.01 0.997 – 1.01 0.197 73637 266539 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.03 0.979 – 1.08 0.273 1893 19027 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.02 0.918 – 1.14 0.693 370 3699 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.02 0.972 – 1.08 0.364 1539 15479 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.02 0.853 – 1.21 0.864 143 1438 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 0.982 0.93 – 1.04 0.502 1472 14771 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1 0.992 – 1.02 0.482 31218 210543 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.985 0.957 – 1.01 0.292 5146 51463 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.01 0.996 – 1.03 0.127 11939 112622 exclusion phecode
411.3 Angina pectoris Circulatory System 0.991 0.975 – 1.01 0.278 15876 143627 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1 0.99 – 1.02 0.526 20156 154515 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.01 0.933 – 1.09 0.822 698 6989 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.01 0.99 – 1.02 0.421 15276 131689 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.967 0.912 – 1.03 0.273 1218 12162 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 0.984 0.938 – 1.03 0.516 1821 18215 exclusion phecode
414.2 ASCVD Circulatory System 0.948 0.748 – 1.2 0.662 72 718 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.01 0.983 – 1.05 0.374 4471 44773 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.05 0.84 – 1.31 0.669 75 749 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.991 0.911 – 1.08 0.834 599 5996 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 0.991 0.899 – 1.09 0.848 447 4470 exclusion phecode
416 Cardiomegaly Circulatory System 1.03 0.99 – 1.07 0.142 2677 26772 exclusion phecode
418 Nonspecific chest pain Circulatory System 0.997 0.985 – 1.01 0.648 28551 269887 exclusion phecode
418.1 Precordial pain Circulatory System 1.02 0.983 – 1.05 0.329 3549 35508 exclusion phecode
420 Carditis Circulatory System 1.02 0.971 – 1.06 0.505 2104 21032 exclusion phecode
420.1 Myocarditis Circulatory System 0.953 0.793 – 1.15 0.609 127 1266 exclusion phecode
420.2 Pericarditis Circulatory System 1.01 0.95 – 1.06 0.855 1337 13355 exclusion phecode
420.21 Acute pericarditis Circulatory System 0.977 0.852 – 1.12 0.735 223 2225 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1 0.829 – 1.22 0.97 112 1128 exclusion phecode
420.3 Endocarditis Circulatory System 1.03 0.958 – 1.12 0.384 718 7188 exclusion phecode
425 Cardiomyopathy Circulatory System 0.962 0.908 – 1.02 0.196 1270 12686 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.967 0.911 – 1.03 0.264 1235 12336 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.07 0.891 – 1.27 0.49 133 1329 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.842 0.713 – 0.995 0.044 163 1627 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 0.873 0.676 – 1.13 0.302 60 600 exclusion phecode
426 Cardiac conduction disorders Circulatory System 0.991 0.966 – 1.02 0.46 6900 69099 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 0.992 0.948 – 1.04 0.73 2110 21148 exclusion phecode
426.21 First degree AV block Circulatory System 0.986 0.923 – 1.05 0.681 984 9858 exclusion phecode
426.23 Second degree AV block Circulatory System 0.996 0.904 – 1.1 0.934 451 4512 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1.01 0.929 – 1.1 0.784 586 5864 exclusion phecode
426.25 Other heart block Circulatory System 0.858 0.712 – 1.03 0.108 130 1317 exclusion phecode
426.3 Bundle branch block Circulatory System 1.01 0.97 – 1.04 0.754 3332 33341 exclusion phecode
426.31 Right bundle branch block Circulatory System 0.991 0.94 – 1.05 0.746 1492 14928 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.01 0.959 – 1.06 0.755 1748 17495 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.958 0.838 – 1.1 0.537 232 2324 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.17 0.911 – 1.51 0.217 60 600 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.974 0.935 – 1.02 0.224 2473 24754 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.989 0.947 – 1.03 0.631 2272 22746 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1 0.989 – 1.02 0.712 24172 205858 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 0.991 0.955 – 1.03 0.606 3195 31999 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.977 0.937 – 1.02 0.287 2341 23460 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.01 0.948 – 1.08 0.679 935 9362 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1 0.987 – 1.02 0.613 14607 133400 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1 0.967 – 1.04 0.897 3222 32260 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.986 0.928 – 1.05 0.637 1192 11909 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.971 0.868 – 1.09 0.6 343 3436 exclusion phecode
427.42 Cardiac arrest Circulatory System 1 0.936 – 1.07 0.999 990 9886 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.994 0.93 – 1.06 0.851 952 9534 exclusion phecode
427.6 Premature beats Circulatory System 1.04 0.956 – 1.14 0.332 534 5357 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1.01 0.832 – 1.23 0.892 116 1168 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.04 0.998 – 1.09 0.0641 2183 21847 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.04 0.938 – 1.15 0.475 401 4025 exclusion phecode
427.9 Palpitations Circulatory System 1.01 0.973 – 1.04 0.726 3804 38065 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.98 0.953 – 1.01 0.149 5599 55977 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1 0.958 – 1.05 0.926 2110 21093 exclusion phecode
428.2 Heart failure NOS Circulatory System 0.98 0.95 – 1.01 0.196 4449 44494 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.02 0.942 – 1.1 0.654 716 7161 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.02 0.795 – 1.32 0.856 64 639 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.05 0.963 – 1.16 0.25 522 5208 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 0.929 0.797 – 1.08 0.344 196 1975 exclusion phecode
430 Intracranial hemorrhage Circulatory System 0.996 0.95 – 1.04 0.871 1881 18806 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.995 0.927 – 1.07 0.89 835 8342 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.01 0.935 – 1.09 0.832 764 7650 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 0.974 0.858 – 1.1 0.68 266 2664 exclusion phecode
433 Cerebrovascular disease Circulatory System 0.988 0.966 – 1.01 0.272 8738 87379 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.942 0.887 – 1 0.0531 1184 11814 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 0.926 0.805 – 1.07 0.286 227 2263 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.988 0.958 – 1.02 0.471 4228 42281 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.993 0.944 – 1.04 0.776 1679 16777 exclusion phecode
433.3 Cerebral ischemia Circulatory System 0.989 0.951 – 1.03 0.567 2891 28962 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 0.99 0.947 – 1.03 0.649 2134 21360 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.09 0.98 – 1.2 0.117 394 3934 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.936 0.883 – 0.993 0.0276 1277 12771 exclusion phecode
440 Atherosclerosis Circulatory System 1.01 0.954 – 1.07 0.774 1378 13815 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.943 0.779 – 1.14 0.546 113 1125 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.03 0.956 – 1.1 0.458 803 8063 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 0.961 0.848 – 1.09 0.532 286 2867 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 0.952 0.877 – 1.03 0.242 611 6148 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.981 0.871 – 1.11 0.759 283 2823 exclusion phecode
442 Other aneurysm Circulatory System 0.999 0.952 – 1.05 0.96 1891 18952 exclusion phecode
442.1 Aortic aneurysm Circulatory System 0.994 0.942 – 1.05 0.832 1457 14619 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.951 0.889 – 1.02 0.146 931 9339 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 0.908 0.736 – 1.12 0.368 102 1019 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.944 0.806 – 1.11 0.475 169 1695 exclusion phecode
442.4 Arterial dissection Circulatory System 1.12 0.844 – 1.49 0.431 54 549 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.01 0.872 – 1.17 0.9 203 2027 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.03 0.992 – 1.06 0.133 3914 39246 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.03 0.968 – 1.09 0.367 1144 11430 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.06 0.959 – 1.18 0.244 383 3875 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.02 0.989 – 1.06 0.182 3680 36879 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.01 0.972 – 1.05 0.567 2574 25828 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.03 0.964 – 1.1 0.366 921 9244 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.05 0.964 – 1.15 0.264 553 5546 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.02 0.954 – 1.1 0.511 821 8217 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 1.14 0.987 – 1.33 0.0744 188 1876 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.03 0.924 – 1.14 0.624 387 3874 exclusion phecode
446.9 Arteritis NOS Circulatory System 0.991 0.87 – 1.13 0.892 239 2399 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 0.974 0.921 – 1.03 0.359 1323 13311 exclusion phecode
447.1 Stricture of artery Circulatory System 0.969 0.904 – 1.04 0.379 865 8706 exclusion phecode
448 Disease of capillaries Circulatory System 1.09 0.917 – 1.29 0.334 142 1420 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.05 0.969 – 1.13 0.239 702 7030 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.99 0.958 – 1.02 0.536 3950 39655 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.989 0.956 – 1.02 0.526 3678 36951 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 0.967 0.886 – 1.05 0.444 562 5642 exclusion phecode
454 Varicose veins Circulatory System 1.01 0.991 – 1.03 0.277 11168 111958 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1.01 0.989 – 1.03 0.391 11488 115171 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.04 0.958 – 1.13 0.352 623 6316 exclusion phecode
455 Hemorrhoids Circulatory System 1.01 0.994 – 1.02 0.313 23425 234404 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1 0.861 – 1.17 0.961 183 1868 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.976 0.798 – 1.19 0.816 97 966 exclusion phecode
458 Hypotension Circulatory System 1 0.975 – 1.03 0.888 5757 57730 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1 0.945 – 1.06 0.996 1332 13368 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1 0.873 – 1.15 0.96 235 2344 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.01 0.973 – 1.04 0.664 3487 34977 exclusion phecode
459 Other disorders of circulatory system Circulatory System 0.993 0.977 – 1.01 0.404 16240 160663 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.04 0.873 – 1.23 0.682 142 1420 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 0.993 0.977 – 1.01 0.381 16075 159295 exclusion phecode
464 Acute sinusitis Respiratory 1.01 0.868 – 1.17 0.936 196 1955 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.997 0.955 – 1.04 0.909 2276 22805 exclusion phecode
465.2 Acute pharyngitis Respiratory 1.01 0.937 – 1.08 0.861 832 8342 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.992 0.848 – 1.16 0.923 162 1649 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.995 0.965 – 1.02 0.72 4651 46528 exclusion phecode
471 Nasal polyps Respiratory 1 0.969 – 1.04 0.829 3297 32953 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.987 0.923 – 1.05 0.689 959 9588 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.01 0.971 – 1.05 0.571 2547 25524 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.13 0.922 – 1.38 0.241 104 1038 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1 0.885 – 1.14 0.958 259 2643 exclusion phecode
473.4 Voice disturbance Respiratory 1.01 0.945 – 1.07 0.839 1078 10784 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1.02 0.97 – 1.07 0.461 1769 17698 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.02 0.938 – 1.11 0.618 548 5481 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.04 0.978 – 1.11 0.211 1120 11193 exclusion phecode
475 Chronic sinusitis Respiratory 0.965 0.927 – 1.01 0.087 2585 25861 exclusion phecode
476 Allergic rhinitis Respiratory 0.998 0.937 – 1.06 0.962 1054 10555 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1 0.961 – 1.04 0.923 2443 24432 exclusion phecode
478 Throat pain Respiratory 0.964 0.866 – 1.07 0.503 375 3782 exclusion phecode
479 Other upper respiratory disease Respiratory 0.972 0.941 – 1 0.0849 4065 40710 exclusion phecode
480 Pneumonia Respiratory 1.01 0.992 – 1.03 0.255 10310 103307 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.02 0.991 – 1.04 0.2 6621 66348 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.02 0.992 – 1.05 0.174 5871 58807 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 0.882 0.706 – 1.1 0.271 91 927 exclusion phecode
480.2 Viral pneumonia Respiratory 0.912 0.717 – 1.16 0.455 72 719 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.16 0.941 – 1.42 0.167 98 989 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.958 0.891 – 1.03 0.253 792 7946 exclusion phecode
481 Influenza Respiratory 0.951 0.85 – 1.06 0.376 328 3275 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.07 0.92 – 1.24 0.388 192 1928 exclusion phecode
495 Asthma Respiratory 1.01 0.997 – 1.02 0.153 25644 250185 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.01 0.888 – 1.15 0.896 248 2506 exclusion phecode
496 Chronic airway obstruction Respiratory 0.997 0.977 – 1.02 0.747 10410 101460 exclusion phecode
496.1 Emphysema Respiratory 1.01 0.963 – 1.06 0.665 1740 17421 exclusion phecode
496.2 Chronic bronchitis Respiratory 0.996 0.959 – 1.04 0.854 2945 29470 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1 0.962 – 1.04 0.953 2704 27057 exclusion phecode
496.3 Bronchiectasis Respiratory 0.993 0.947 – 1.04 0.777 1883 18850 exclusion phecode
497 Bronchitis Respiratory 1.04 0.959 – 1.13 0.343 626 6261 exclusion phecode
500 Lung disease due to external agents Respiratory 0.993 0.898 – 1.1 0.896 411 4095 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.785 0.621 – 0.992 0.0422 79 784 exclusion phecode
500.2 Pneumoconiosis Respiratory 1.01 0.892 – 1.15 0.823 242 2408 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.07 0.99 – 1.16 0.0857 653 6551 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.995 0.929 – 1.07 0.882 916 9183 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1 0.916 – 1.1 0.94 507 5075 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1 0.893 – 1.12 0.998 328 3277 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.21 0.947 – 1.55 0.126 61 610 exclusion phecode
506 Empyema and pneumothorax Respiratory 1 0.944 – 1.07 0.904 1130 11352 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.02 0.992 – 1.04 0.173 6404 64202 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.01 0.967 – 1.06 0.606 1991 19925 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.988 0.948 – 1.03 0.555 2597 26006 exclusion phecode
509.1 Respiratory failure Respiratory 0.976 0.932 – 1.02 0.297 2067 20686 exclusion phecode
509.2 Respiratory insufficiency Respiratory 0.964 0.918 – 1.01 0.147 1805 18088 exclusion phecode
509.5 Respiratory arrest Respiratory 0.961 0.812 – 1.14 0.645 143 1429 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.05 0.942 – 1.16 0.399 385 3856 exclusion phecode
510 Other diseases of lung Respiratory 0.937 0.869 – 1.01 0.093 750 7545 exclusion phecode
512 Other symptoms of respiratory system Respiratory 0.996 0.975 – 1.02 0.717 9019 90268 exclusion phecode
512.1 Wheezing Respiratory 1.01 0.881 – 1.16 0.872 219 2196 exclusion phecode
512.2 Painful respiration Respiratory 0.986 0.857 – 1.13 0.839 207 2074 exclusion phecode
512.7 Shortness of breath Respiratory 0.998 0.972 – 1.03 0.912 5832 58448 exclusion phecode
512.8 Cough Respiratory 0.966 0.929 – 1 0.079 2864 28614 exclusion phecode
512.9 Other dyspnea Respiratory 1.03 0.964 – 1.1 0.367 913 9116 exclusion phecode
513 Respiratory abnormalities Respiratory 1 0.921 – 1.09 0.995 608 6107 exclusion phecode
513.3 Hypoventilation Respiratory 0.984 0.783 – 1.24 0.889 83 829 exclusion phecode
513.4 Hyperventilation Respiratory 0.986 0.871 – 1.12 0.823 277 2774 exclusion phecode
513.8 Disorders of diaphragm Respiratory 0.98 0.831 – 1.16 0.811 152 1538 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 0.989 0.949 – 1.03 0.606 2459 24656 exclusion phecode
516 Abnormal sputum Respiratory 1.02 0.974 – 1.06 0.425 2127 21317 exclusion phecode
516.1 Hemoptysis Respiratory 1.02 0.974 – 1.07 0.408 2068 20728 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.01 0.99 – 1.03 0.317 9341 93606 exclusion phecode
519.2 Respiratory complications Respiratory 1.05 0.937 – 1.18 0.402 325 3279 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.01 0.984 – 1.03 0.581 8830 88450 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.04 0.93 – 1.17 0.477 302 3047 exclusion phecode
520 Disorders of tooth development Digestive 0.998 0.954 – 1.05 0.943 2037 20336 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.02 0.779 – 1.35 0.864 53 529 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.998 0.957 – 1.04 0.942 2354 23518 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 0.993 0.957 – 1.03 0.714 3011 30221 exclusion phecode
521.1 Dental caries Digestive 0.997 0.961 – 1.04 0.89 3021 30329 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1 0.956 – 1.05 0.897 1773 17742 exclusion phecode
522.5 Periapical abscess Digestive 0.988 0.931 – 1.05 0.701 1172 11723 exclusion phecode
523 Gingival and periodontal diseases Digestive 0.983 0.935 – 1.03 0.496 1681 16801 exclusion phecode
523.1 Gingivitis Digestive 1.01 0.823 – 1.23 0.952 113 1127 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 0.98 0.923 – 1.04 0.512 1165 11643 exclusion phecode
523.31 Acute periodontitis Digestive 0.979 0.903 – 1.06 0.602 666 6664 exclusion phecode
523.32 Chronic periodontitis Digestive 1 0.918 – 1.09 0.984 559 5592 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.977 0.871 – 1.09 0.683 330 3303 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1 0.891 – 1.13 0.953 304 3042 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.01 0.974 – 1.06 0.5 2662 26701 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.958 0.749 – 1.22 0.729 72 717 exclusion phecode
526 Diseases of the jaws Digestive 0.974 0.91 – 1.04 0.444 926 9273 exclusion phecode
526.1 Cysts of the jaws Digestive 0.917 0.819 – 1.03 0.13 329 3289 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.84 0.645 – 1.09 0.198 61 608 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.02 0.894 – 1.17 0.758 238 2402 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.01 0.886 – 1.16 0.841 231 2333 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.991 0.815 – 1.21 0.93 110 1096 exclusion phecode
526.9 Jaw disease NOS Digestive 1.08 0.942 – 1.24 0.273 233 2329 exclusion phecode
527 Diseases of the salivary glands Digestive 0.985 0.911 – 1.06 0.702 693 6936 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.14 0.914 – 1.42 0.244 84 836 exclusion phecode
527.2 Sialoadenitis Digestive 0.933 0.837 – 1.04 0.206 365 3653 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 0.992 0.756 – 1.3 0.957 61 618 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.1 0.911 – 1.32 0.33 120 1200 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1 0.971 – 1.04 0.842 3868 38696 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.01 0.921 – 1.11 0.802 467 4668 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.01 0.908 – 1.12 0.896 388 3879 exclusion phecode
528.12 Oral aphthae Digestive 1.06 0.852 – 1.33 0.585 84 839 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.998 0.856 – 1.16 0.976 179 1787 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.982 0.815 – 1.18 0.853 122 1215 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.989 0.8 – 1.22 0.915 94 939 exclusion phecode
528.5 Diseases of lips Digestive 1.06 0.979 – 1.14 0.156 680 6804 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.02 0.907 – 1.15 0.735 308 3077 exclusion phecode
528.7 Sialolithiasis Digestive 0.984 0.875 – 1.11 0.782 314 3133 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.02 0.957 – 1.08 0.617 1229 12300 exclusion phecode
529.1 Glossitis Digestive 0.977 0.868 – 1.1 0.702 298 2983 exclusion phecode
530 Diseases of esophagus Digestive 1.01 0.998 – 1.02 0.11 33413 278950 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.01 0.997 – 1.02 0.165 31214 272215 exclusion phecode
530.11 GERD Digestive 1.01 0.993 – 1.02 0.36 22607 225700 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.03 1 – 1.06 0.0374 5198 52039 exclusion phecode
530.14 Reflux esophagitis Digestive 1.01 0.99 – 1.03 0.317 10435 104420 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.01 0.959 – 1.06 0.756 1679 16801 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1.04 0.993 – 1.09 0.0943 1868 18675 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.01 0.933 – 1.1 0.766 635 6361 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.832 0.703 – 0.984 0.0318 152 1527 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.973 0.872 – 1.09 0.632 340 3414 exclusion phecode
530.9 Heartburn Digestive 1.01 0.968 – 1.06 0.586 2082 20863 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1 0.976 – 1.03 0.967 7097 71006 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.981 0.905 – 1.06 0.651 637 6372 exclusion phecode
531.2 Gastric ulcer Digestive 0.999 0.968 – 1.03 0.961 4087 40905 exclusion phecode
531.3 Duodenal ulcer Digestive 0.99 0.954 – 1.03 0.608 2997 29988 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 0.992 0.898 – 1.1 0.874 426 4263 exclusion phecode
532 Dysphagia Digestive 1.02 0.993 – 1.05 0.155 6411 64283 exclusion phecode
535 Gastritis and duodenitis Digestive 0.999 0.987 – 1.01 0.89 28052 261321 exclusion phecode
535.1 Acute gastritis Digestive 0.961 0.906 – 1.02 0.196 1180 11821 exclusion phecode
535.2 Atrophic gastritis Digestive 1.08 0.973 – 1.21 0.141 370 3684 exclusion phecode
535.6 Duodenitis Digestive 1 0.98 – 1.03 0.786 7586 75867 exclusion phecode
535.8 Other specified gastritis Digestive 0.999 0.977 – 1.02 0.956 8066 80695 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.943 0.785 – 1.13 0.532 120 1190 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.01 0.891 – 1.15 0.87 258 2573 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 0.992 0.958 – 1.03 0.674 3388 33882 exclusion phecode
540 Appendiceal conditions Digestive 0.994 0.958 – 1.03 0.769 3084 30850 exclusion phecode
540.1 Appendicitis Digestive 0.993 0.955 – 1.03 0.717 2891 28925 exclusion phecode
540.11 Acute appendicitis Digestive 0.999 0.959 – 1.04 0.956 2597 25978 exclusion phecode
550 Abdominal hernia Digestive 1 0.993 – 1.01 0.568 45377 282423 exclusion phecode
550.1 Inguinal hernia Digestive 1 0.986 – 1.02 0.79 15783 123179 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.01 0.993 – 1.02 0.346 26456 238762 exclusion phecode
550.3 Femoral hernia Digestive 1.01 0.931 – 1.1 0.813 650 6498 exclusion phecode
550.4 Umbilical hernia Digestive 0.986 0.954 – 1.02 0.416 3702 37054 exclusion phecode
550.5 Ventral hernia Digestive 0.999 0.964 – 1.03 0.957 3432 34307 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 0.99 0.959 – 1.02 0.506 4439 44412 exclusion phecode
555.1 Regional enteritis Digestive 0.997 0.948 – 1.05 0.895 1732 17325 exclusion phecode
555.2 Ulcerative colitis Digestive 0.991 0.956 – 1.03 0.639 3175 31763 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.1 1 – 1.2 0.041 538 5378 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.05 0.987 – 1.12 0.121 1054 10583 exclusion phecode
556.1 Ulceration of intestine Digestive 1.03 0.952 – 1.12 0.458 669 6710 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.809 0.716 – 0.915 0.00076 299 2984 exclusion phecode
557.1 Celiac disease Digestive 1 0.957 – 1.05 0.872 1837 18372 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1 0.987 – 1.02 0.669 15475 154968 exclusion phecode
559 Ileostomy status Digestive 1.02 0.974 – 1.08 0.361 1650 16530 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.02 0.99 – 1.06 0.172 3928 39311 exclusion phecode
560.1 Paralytic ileus Digestive 0.998 0.911 – 1.09 0.957 523 5227 exclusion phecode
560.2 Impaction of intestine Digestive 1.06 0.941 – 1.2 0.321 268 2670 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.99 0.921 – 1.06 0.778 829 8311 exclusion phecode
560.4 Other intestinal obstruction Digestive 1.03 0.99 – 1.06 0.166 3350 33526 exclusion phecode
561 Symptoms involving digestive system Digestive 0.998 0.982 – 1.01 0.791 15755 157542 exclusion phecode
561.1 Diarrhea Digestive 1.03 0.936 – 1.13 0.547 466 4648 exclusion phecode
561.2 Flatulence Digestive 1.02 0.966 – 1.07 0.544 1685 16842 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1.02 1.01 – 1.03 0.00141 26680 211537 exclusion phecode
562.1 Diverticulosis Digestive 1.02 1.01 – 1.03 0.00102 26639 211487 exclusion phecode
563 Constipation Digestive 1 0.98 – 1.02 0.968 10300 103060 exclusion phecode
564 Functional digestive disorders Digestive 1 0.99 – 1.02 0.571 21609 209781 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.01 0.985 – 1.04 0.353 5499 55060 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 0.979 0.93 – 1.03 0.407 1644 16442 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1 0.985 – 1.02 0.865 15164 151525 exclusion phecode
565 Anal and rectal conditions Digestive 1 0.987 – 1.02 0.627 14737 147423 exclusion phecode
565.1 Anal and rectal polyp Digestive 1.01 0.986 – 1.03 0.408 7348 73478 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.02 0.95 – 1.09 0.647 929 9283 exclusion phecode
568 Other disorders of peritoneum Digestive 0.998 0.962 – 1.03 0.898 3257 32574 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.994 0.957 – 1.03 0.733 3095 30960 exclusion phecode
569 Other disorders of intestine Digestive 1 0.972 – 1.04 0.826 4186 41888 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1 0.841 – 1.19 0.999 147 1479 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.01 0.916 – 1.11 0.896 485 4865 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1 0.967 – 1.04 0.823 2955 29607 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.02 0.966 – 1.07 0.545 1689 16902 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.02 0.843 – 1.24 0.829 113 1138 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.1 0.968 – 1.24 0.147 257 2567 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.967 0.905 – 1.03 0.325 975 9800 exclusion phecode
571.81 Portal hypertension Digestive 0.964 0.882 – 1.05 0.419 527 5282 exclusion phecode
572 Ascites (non malignant) Digestive 0.993 0.943 – 1.05 0.799 1543 15439 exclusion phecode
573 Other disorders of liver Digestive 1.02 0.964 – 1.07 0.538 1490 14968 exclusion phecode
573.2 Liver replaced by transplant Digestive 0.957 0.779 – 1.17 0.672 96 960 exclusion phecode
573.3 Hepatomegaly Digestive 0.967 0.856 – 1.09 0.59 297 2965 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 0.998 0.931 – 1.07 0.953 895 8948 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.01 0.976 – 1.05 0.548 3447 34576 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 0.97 0.838 – 1.12 0.687 209 2085 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1 0.986 – 1.02 0.792 15586 155976 exclusion phecode
574.1 Cholelithiasis Digestive 0.997 0.979 – 1.01 0.704 13529 135403 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.973 0.922 – 1.03 0.308 1503 15054 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.987 0.96 – 1.02 0.366 5424 54234 exclusion phecode
574.2 Calculus of bile duct Digestive 1.01 0.969 – 1.05 0.694 2616 26166 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.01 0.968 – 1.05 0.734 2744 27502 exclusion phecode
575 Other biliary tract disease Digestive 0.988 0.955 – 1.02 0.465 3860 38699 exclusion phecode
575.1 Cholangitis Digestive 0.948 0.863 – 1.04 0.261 494 4941 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.01 0.943 – 1.09 0.699 772 7752 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.949 0.862 – 1.04 0.286 457 4574 exclusion phecode
575.7 Other disorders of gallbladder Digestive 0.991 0.938 – 1.05 0.759 1406 14099 exclusion phecode
575.8 Other disorders of biliary tract Digestive 0.966 0.906 – 1.03 0.286 1035 10357 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.03 0.924 – 1.15 0.569 348 3486 exclusion phecode
577 Diseases of pancreas Digestive 1.03 0.994 – 1.08 0.0966 2666 26654 exclusion phecode
577.1 Acute pancreatitis Digestive 1.03 0.98 – 1.07 0.273 1994 19942 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.03 0.939 – 1.13 0.555 515 5147 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.11 1 – 1.24 0.0472 365 3649 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.992 – 1.02 0.399 20603 206105 exclusion phecode
578.1 Hematemesis Digestive 0.964 0.92 – 1.01 0.12 1951 19548 exclusion phecode
578.2 Blood in stool Digestive 0.958 0.92 – 0.997 0.0368 2623 26274 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.01 0.993 – 1.03 0.216 13064 130626 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.01 0.981 – 1.04 0.518 5269 52753 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.951 0.902 – 1 0.0591 1547 15490 exclusion phecode
579.2 Splenomegaly Digestive 0.943 0.853 – 1.04 0.25 422 4246 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.02 0.966 – 1.07 0.55 1651 16525 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.989 0.937 – 1.04 0.672 1527 15343 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.02 0.953 – 1.08 0.642 1048 10537 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.915 0.729 – 1.15 0.445 74 737 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.1 0.92 – 1.31 0.305 134 1359 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.01 0.943 – 1.08 0.758 873 8764 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.03 0.938 – 1.14 0.516 468 4697 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.892 0.782 – 1.02 0.0892 246 2457 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.893 0.784 – 1.02 0.0888 253 2526 exclusion phecode
585 Renal failure Genitourinary 1.01 0.982 – 1.03 0.599 6953 69704 exclusion phecode
585.1 Acute renal failure Genitourinary 1.01 0.983 – 1.05 0.374 4516 45272 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.04 0.982 – 1.09 0.199 1456 14616 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.01 0.975 – 1.06 0.473 2637 26473 exclusion phecode
585.31 Renal dialysis Genitourinary 0.951 0.866 – 1.04 0.293 493 4949 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 0.975 0.941 – 1.01 0.171 3350 33551 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1 0.869 – 1.16 0.961 207 2087 exclusion phecode
586.11 Small kidney Genitourinary 0.974 0.836 – 1.13 0.735 179 1797 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.01 0.949 – 1.07 0.825 1256 12569 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.885 0.706 – 1.11 0.292 80 798 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.944 0.882 – 1.01 0.102 909 9114 exclusion phecode
587 Kidney replaced by transpant Genitourinary 0.959 0.86 – 1.07 0.445 366 3679 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 0.835 0.676 – 1.03 0.093 98 987 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 0.996 0.824 – 1.2 0.965 115 1158 exclusion phecode
590 Pyelonephritis Genitourinary 1.03 0.976 – 1.09 0.27 1325 13280 exclusion phecode
591 Urinary tract infection Genitourinary 0.997 0.979 – 1.02 0.758 12383 123825 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.03 0.995 – 1.07 0.089 2960 29633 exclusion phecode
592.1 Cystitis Genitourinary 1.03 0.996 – 1.08 0.0765 2898 29009 exclusion phecode
592.11 Acute cystitis Genitourinary 0.955 0.805 – 1.13 0.599 138 1372 exclusion phecode
592.12 Chronic cystitis Genitourinary 1.04 0.973 – 1.12 0.242 887 8881 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.09 0.955 – 1.23 0.208 249 2483 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.1 0.944 – 1.29 0.218 165 1659 exclusion phecode
593 Hematuria Genitourinary 1 0.987 – 1.02 0.668 16048 160078 exclusion phecode
594 Urinary calculus Genitourinary 0.995 0.969 – 1.02 0.678 6367 63724 exclusion phecode
594.1 Calculus of kidney Genitourinary 0.995 0.96 – 1.03 0.8 3168 31734 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 0.977 0.907 – 1.05 0.534 775 7761 exclusion phecode
594.3 Calculus of ureter Genitourinary 1 0.963 – 1.05 0.833 2398 24008 exclusion phecode
594.8 Renal colic Genitourinary 1.01 0.968 – 1.06 0.589 2049 20489 exclusion phecode
595 Hydronephrosis Genitourinary 0.999 0.954 – 1.05 0.981 1935 19378 exclusion phecode
596 Other disorders of bladder Genitourinary 1 0.983 – 1.02 0.735 9758 97709 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 0.997 0.952 – 1.04 0.906 1968 19679 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 0.98 0.932 – 1.03 0.443 1653 16557 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.01 0.981 – 1.05 0.41 3905 39108 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1 0.966 – 1.04 0.961 3312 33119 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.01 0.806 – 1.27 0.907 78 776 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1 0.97 – 1.04 0.794 3527 35273 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.878 0.779 – 0.99 0.0335 304 3031 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1 0.989 – 1.02 0.634 18394 184138 exclusion phecode
599.1 Urinary obstruction Genitourinary 1.13 0.969 – 1.32 0.119 166 1670 exclusion phecode
599.2 Retention of urine Genitourinary 0.977 0.953 – 1 0.0716 6713 67121 exclusion phecode
599.3 Dysuria Genitourinary 1.01 0.95 – 1.07 0.788 1193 11957 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.991 0.969 – 1.01 0.429 8729 87371 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.01 0.976 – 1.04 0.633 4008 40112 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.08 0.891 – 1.32 0.423 105 1058 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.19 0.912 – 1.54 0.202 62 619 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1.02 0.972 – 1.07 0.426 1910 19134 exclusion phecode
600 Hyperplasia of prostate Genitourinary 1 0.983 – 1.02 0.774 11089 87844 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 1.03 0.981 – 1.07 0.262 2076 20806 exclusion phecode
601.1 Prostatitis Genitourinary 1.02 0.97 – 1.07 0.437 1561 15637 exclusion phecode
601.11 Acute prostatitis Genitourinary 1.03 0.903 – 1.18 0.63 234 2358 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1.03 0.962 – 1.1 0.402 909 9084 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 1.01 0.764 – 1.32 0.972 59 587 exclusion phecode
601.4 Balanoposthitis Genitourinary 0.948 0.84 – 1.07 0.394 285 2864 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.05 0.936 – 1.18 0.401 302 3015 exclusion phecode
602 Other disorders of prostate Genitourinary 1.02 0.966 – 1.08 0.465 1340 13404 exclusion phecode
603 Other disorders of testis Genitourinary 0.981 0.938 – 1.02 0.387 2149 21504 exclusion phecode
603.1 Hydrocele Genitourinary 0.947 0.896 – 1 0.057 1339 13395 exclusion phecode
604 Disorders of penis Genitourinary 0.986 0.951 – 1.02 0.426 3274 32770 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.989 0.951 – 1.03 0.569 2713 27165 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 1.04 0.921 – 1.17 0.543 276 2800 exclusion phecode
608 Other disorders of male genital organs Genitourinary 0.974 0.937 – 1.01 0.19 2819 28228 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.04 0.897 – 1.2 0.632 214 2137 exclusion phecode
609.1 Infertility, male Genitourinary 0.96 0.746 – 1.24 0.753 63 637 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 1.05 0.9 – 1.23 0.519 169 1698 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.985 0.946 – 1.03 0.484 2478 24775 exclusion phecode
610.1 Cystic mastopathy Genitourinary 1.02 0.953 – 1.09 0.589 924 9238 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1.02 0.909 – 1.15 0.694 306 3052 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 0.984 0.874 – 1.11 0.788 302 3017 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.979 0.926 – 1.03 0.443 1385 13847 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.01 0.931 – 1.09 0.864 693 6950 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1 0.954 – 1.06 0.853 1571 15704 exclusion phecode
611.1 Abnormal mammogram Genitourinary 1.07 0.826 – 1.39 0.603 57 569 exclusion phecode
611.3 Lump or mass in breast Genitourinary 1 0.953 – 1.06 0.863 1519 15189 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.964 0.899 – 1.03 0.296 886 8860 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.966 0.9 – 1.04 0.337 848 8480 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 1.15 0.914 – 1.46 0.228 72 718 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 1 0.952 – 1.05 0.941 1647 16498 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.03 0.955 – 1.11 0.429 719 7200 exclusion phecode
613.5 Mastodynia Genitourinary 0.9 0.711 – 1.14 0.382 77 767 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 1.02 0.944 – 1.1 0.633 699 7004 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1.01 0.899 – 1.13 0.912 326 3274 exclusion phecode
613.9 Breast disorder NOS Genitourinary 1.1 0.952 – 1.26 0.201 207 2069 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.972 0.946 – 0.999 0.0421 5705 57066 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.961 0.923 – 1 0.0592 2534 25332 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.01 0.941 – 1.08 0.777 830 8295 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.2 0.949 – 1.52 0.127 61 605 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.01 0.917 – 1.12 0.802 422 4215 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.05 0.948 – 1.17 0.328 351 3507 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.02 0.903 – 1.15 0.764 277 2775 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.973 0.934 – 1.01 0.181 2599 25998 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.984 0.93 – 1.04 0.589 1317 13172 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.906 0.819 – 1 0.054 428 4271 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.01 0.934 – 1.08 0.863 754 7567 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.976 0.864 – 1.1 0.695 273 2736 exclusion phecode
615 Endometriosis Genitourinary 0.981 0.949 – 1.01 0.243 4022 40243 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.03 0.921 – 1.16 0.571 304 3035 exclusion phecode
618 Genital prolapse Genitourinary 0.996 0.977 – 1.02 0.707 11674 116741 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 1 0.978 – 1.03 0.899 7381 73851 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1 0.973 – 1.03 0.966 5386 53860 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.962 0.877 – 1.06 0.413 512 5115 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.971 0.896 – 1.05 0.466 680 6792 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 0.973 0.952 – 0.995 0.0156 8714 87211 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.942 0.873 – 1.02 0.123 728 7273 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 0.996 0.961 – 1.03 0.813 3320 33230 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.961 0.924 – 0.999 0.0423 2855 28586 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1 0.955 – 1.05 0.919 1766 17649 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.982 0.928 – 1.04 0.522 1346 13471 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 0.87 0.683 – 1.11 0.26 72 718 exclusion phecode
621 Endometrial hyperplasia Genitourinary 1 0.941 – 1.06 0.991 1129 11285 exclusion phecode
622 Polyp of female genital organs Genitourinary 1.02 1 – 1.04 0.05 10464 104693 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 1.03 1 – 1.05 0.0224 7846 78517 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 1.01 0.979 – 1.05 0.434 3435 34352 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 0.98 0.925 – 1.04 0.502 1266 12673 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.97 0.901 – 1.04 0.413 795 7956 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.956 0.838 – 1.09 0.499 237 2363 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 0.979 0.887 – 1.08 0.673 440 4396 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.986 0.959 – 1.01 0.291 5848 58553 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.964 0.928 – 1 0.0584 2871 28704 exclusion phecode
625.1 Dyspareunia Genitourinary 1.02 0.959 – 1.08 0.58 1187 11874 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1 0.986 – 1.02 0.74 16146 114906 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.999 0.982 – 1.02 0.942 14090 109810 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.952 0.783 – 1.16 0.619 109 1098 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1.01 0.986 – 1.03 0.504 9712 91649 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.983 0.939 – 1.03 0.456 1983 19814 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.984 0.952 – 1.02 0.359 3799 37993 exclusion phecode
626.2 Dysmenorrhea Genitourinary 1.02 0.971 – 1.07 0.434 1777 17748 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.966 0.822 – 1.14 0.678 158 1584 exclusion phecode
626.8 Infertility, female Genitourinary 1.03 0.977 – 1.09 0.262 1360 13600 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.996 0.976 – 1.02 0.71 10376 103838 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 0.999 0.977 – 1.02 0.897 9030 90340 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.912 0.783 – 1.06 0.235 182 1826 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.962 0.904 – 1.02 0.229 1107 11102 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 0.947 0.843 – 1.06 0.355 309 3094 exclusion phecode
628 Ovarian cyst Genitourinary 0.961 0.932 – 0.99 0.00862 4735 47438 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.02 0.986 – 1.05 0.315 5210 36388 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.08 1.01 – 1.14 0.015 1136 11292 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.96 0.856 – 1.08 0.483 331 3305 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.99 0.944 – 1.04 0.667 1969 17359 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.969 0.903 – 1.04 0.39 863 8610 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.02 0.963 – 1.08 0.487 1267 12296 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.996 0.954 – 1.04 0.862 2341 19956 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.916 0.842 – 0.996 0.0409 616 6137 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.991 0.931 – 1.05 0.771 1078 10755 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 0.938 0.739 – 1.19 0.6 70 700 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.994 0.934 – 1.06 0.841 1109 11058 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.953 0.848 – 1.07 0.423 306 3052 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.944 0.82 – 1.09 0.426 215 2146 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.95 0.805 – 1.12 0.548 153 1524 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.02 0.958 – 1.08 0.593 1250 12433 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.02 0.977 – 1.07 0.353 2224 20828 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.935 0.728 – 1.2 0.597 68 679 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.976 0.862 – 1.11 0.706 275 2746 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.966 0.796 – 1.17 0.727 112 1128 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.05 0.904 – 1.22 0.53 193 1922 exclusion phecode
650 Normal delivery Pregnancy Complications 1.01 0.959 – 1.05 0.816 1920 18952 exclusion phecode
651 Multiple gestation Pregnancy Complications 0.954 0.852 – 1.07 0.412 345 3451 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1.01 0.961 – 1.06 0.679 1716 16504 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.967 0.915 – 1.02 0.24 1399 13635 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.27 1 – 1.61 0.0464 74 737 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.982 0.951 – 1.01 0.274 4301 29425 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.8 0.654 – 0.978 0.0298 109 1078 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.996 0.953 – 1.04 0.868 2264 18381 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.968 0.885 – 1.06 0.476 532 5312 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 1.01 0.98 – 1.04 0.526 5306 29441 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.987 0.947 – 1.03 0.532 2550 21151 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.07 0.905 – 1.26 0.444 164 1624 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.04 0.911 – 1.18 0.59 262 2603 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.14 0.89 – 1.45 0.304 63 623 exclusion phecode
679 Complications of in utero procedures Dermatologic 0.89 0.674 – 1.18 0.413 53 530 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.01 0.987 – 1.04 0.362 7191 72169 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.08 0.996 – 1.18 0.0615 562 5640 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.95 0.869 – 1.04 0.267 520 5203 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1 0.973 – 1.03 0.955 5476 54971 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1 0.972 – 1.03 0.976 5482 55031 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.998 0.97 – 1.03 0.872 5439 54600 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.06 0.975 – 1.15 0.17 595 5982 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 0.999 0.945 – 1.06 0.982 1335 13421 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.01 0.969 – 1.06 0.593 2282 22909 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.07 0.987 – 1.17 0.0963 583 5835 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 0.988 0.887 – 1.1 0.83 362 3611 exclusion phecode
687 Symptoms affecting skin Dermatologic 1 0.918 – 1.09 0.966 547 5503 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.953 0.911 – 0.997 0.0352 2141 21452 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 0.97 0.858 – 1.1 0.622 282 2838 exclusion phecode
687.3 Changes in skin texture Dermatologic 1.11 0.907 – 1.36 0.315 106 1068 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.02 0.977 – 1.06 0.429 2878 28841 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.988 0.961 – 1.02 0.38 5742 57478 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.969 0.771 – 1.22 0.784 71 710 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 1.03 0.795 – 1.34 0.813 53 530 exclusion phecode
691 Congenital anomalies of skin Dermatologic 1.15 0.959 – 1.38 0.13 120 1198 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 1.02 0.954 – 1.09 0.582 984 9846 exclusion phecode
694.1 Vitiligo Dermatologic 0.901 0.689 – 1.18 0.447 60 599 exclusion phecode
694.2 Other dyschromia Dermatologic 1.01 0.934 – 1.08 0.892 780 7814 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.11 0.922 – 1.33 0.273 117 1169 exclusion phecode
695 Erythematous conditions Dermatologic 0.963 0.923 – 1 0.0825 2377 23794 exclusion phecode
695.1 Toxic erythema Dermatologic 1.1 0.908 – 1.34 0.322 108 1090 exclusion phecode
695.2 Bullous dermatoses Dermatologic 0.954 0.801 – 1.14 0.601 137 1365 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 0.863 0.649 – 1.15 0.313 57 569 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.984 0.781 – 1.24 0.888 73 727 exclusion phecode
695.3 Rosacea Dermatologic 1.13 1.01 – 1.27 0.0385 309 3095 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 0.913 0.824 – 1.01 0.084 411 4109 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.843 0.7 – 1.02 0.072 130 1292 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 0.921 0.823 – 1.03 0.15 340 3403 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 0.987 0.917 – 1.06 0.735 775 7756 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 0.836 0.73 – 0.958 0.0101 236 2357 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.888 0.703 – 1.12 0.323 76 760 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 0.911 0.828 – 1 0.0573 466 4669 exclusion phecode
696 Psoriasis and related disorders Dermatologic 1.01 0.969 – 1.06 0.598 2251 22492 exclusion phecode
696.4 Psoriasis Dermatologic 1.02 0.975 – 1.06 0.414 2197 21951 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 1 0.953 – 1.05 0.934 1679 16779 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.992 0.918 – 1.07 0.831 706 7049 exclusion phecode
697 Sarcoidosis Dermatologic 1.01 0.923 – 1.1 0.866 538 5369 exclusion phecode
698 Pruritus and related conditions Dermatologic 1.05 0.978 – 1.13 0.173 781 7806 exclusion phecode
700 Corns and callosities Dermatologic 0.996 0.884 – 1.12 0.948 291 2899 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.03 1 – 1.06 0.036 4658 46603 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.802 0.643 – 1 0.052 87 869 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.04 1 – 1.09 0.0481 2345 23458 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 1.03 0.792 – 1.33 0.85 61 609 exclusion phecode
701.4 Keloid scar Dermatologic 1.04 0.909 – 1.2 0.542 216 2157 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1.08 0.985 – 1.19 0.0999 455 4560 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.23 1 – 1.5 0.0454 102 1019 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.03 0.998 – 1.05 0.0719 5452 54540 exclusion phecode
702.1 Actinic keratosis Dermatologic 1.03 0.985 – 1.07 0.225 2580 25821 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 1.03 0.994 – 1.07 0.0992 3075 30743 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.04 0.933 – 1.16 0.48 353 3535 exclusion phecode
703.1 Ingrowing nail Dermatologic 1.02 0.956 – 1.09 0.536 966 9658 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 1.03 0.997 – 1.06 0.0748 5262 52685 exclusion phecode
704.1 Alopecia Dermatologic 1.1 0.92 – 1.31 0.303 125 1267 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.07 0.856 – 1.34 0.544 76 759 exclusion phecode
705 Disorders of sweat glands Dermatologic 0.974 0.85 – 1.12 0.709 227 2282 exclusion phecode
705.3 Hidradenitis Dermatologic 0.969 0.833 – 1.13 0.682 185 1864 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.02 0.936 – 1.11 0.687 591 5916 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1.02 0.995 – 1.04 0.135 8308 83129 exclusion phecode
706.1 Acne Dermatologic 0.953 0.758 – 1.2 0.681 78 779 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1.01 0.993 – 1.04 0.193 8776 87813 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.01 0.966 – 1.06 0.626 1947 19638 exclusion phecode
707.1 Decubitus ulcer Dermatologic 0.98 0.915 – 1.05 0.573 906 9091 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.992 0.957 – 1.03 0.65 3427 34285 exclusion phecode
709.2 Sicca syndrome Dermatologic 0.982 0.896 – 1.08 0.695 506 5066 exclusion phecode
709.3 Systemic sclerosis Dermatologic 0.917 0.781 – 1.08 0.292 175 1752 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.874 0.673 – 1.13 0.312 65 649 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.998 0.959 – 1.04 0.926 2711 27121 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.03 0.946 – 1.12 0.515 599 6029 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.06 0.972 – 1.16 0.186 553 5570 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1 0.868 – 1.16 0.967 194 1946 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.06 0.959 – 1.18 0.247 395 3994 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 0.98 0.886 – 1.08 0.696 420 4221 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 0.936 0.835 – 1.05 0.263 328 3291 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 0.807 0.635 – 1.03 0.0796 80 807 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.09 0.918 – 1.29 0.332 148 1499 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.05 0.813 – 1.35 0.725 65 669 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.02 0.987 – 1.05 0.284 4829 48279 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.03 0.994 – 1.06 0.108 4371 43678 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.967 0.92 – 1.02 0.196 1655 16573 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.04 0.862 – 1.26 0.666 113 1127 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.915 0.842 – 0.994 0.0357 616 6174 exclusion phecode
716 Other arthropathies Musculoskeletal 0.998 0.987 – 1.01 0.72 37428 265159 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.981 0.947 – 1.02 0.285 3500 35061 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.994 0.978 – 1.01 0.489 15505 155219 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 0.998 0.987 – 1.01 0.712 35896 262093 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.968 0.91 – 1.03 0.291 1145 11467 exclusion phecode
720 Spinal stenosis Musculoskeletal 1 0.97 – 1.04 0.83 3703 37058 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1 0.981 – 1.03 0.752 7819 78249 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1 0.975 – 1.03 0.784 5036 50403 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.12 0.965 – 1.29 0.137 188 1896 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 0.969 0.867 – 1.08 0.581 351 3512 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1 0.983 – 1.03 0.666 8969 89781 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.97 0.887 – 1.06 0.511 511 5110 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.03 0.993 – 1.07 0.113 2829 28302 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.04 0.818 – 1.32 0.751 67 669 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.988 0.958 – 1.02 0.462 4403 44097 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 0.982 0.896 – 1.08 0.694 516 5166 exclusion phecode
723.1 Torticollis Musculoskeletal 0.972 0.799 – 1.18 0.778 107 1067 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 0.997 0.953 – 1.04 0.902 2050 20494 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 0.986 0.89 – 1.09 0.788 403 4022 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.979 0.884 – 1.08 0.684 406 4053 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.14 0.882 – 1.48 0.313 63 630 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 0.992 0.942 – 1.04 0.753 1612 16122 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.994 0.977 – 1.01 0.486 14657 146556 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.996 0.975 – 1.02 0.701 9586 95819 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.933 0.835 – 1.04 0.225 333 3332 exclusion phecode
726.3 Bursitis Musculoskeletal 0.994 0.926 – 1.07 0.862 854 8566 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.995 0.971 – 1.02 0.664 7322 73269 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.996 0.957 – 1.04 0.831 2736 27383 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 1.11 0.904 – 1.35 0.33 103 1025 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.986 0.95 – 1.02 0.467 3101 31057 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.977 0.897 – 1.06 0.588 586 5847 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.03 0.923 – 1.15 0.595 353 3524 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.07 0.907 – 1.27 0.41 143 1426 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.03 0.997 – 1.07 0.0777 3673 36761 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.02 0.918 – 1.12 0.766 412 4112 exclusion phecode
728.7 Fasciitis Musculoskeletal 1.03 0.998 – 1.07 0.0673 3799 38018 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.03 0.994 – 1.07 0.105 3473 34764 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 0.99 0.964 – 1.02 0.467 6009 60247 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.923 0.864 – 0.986 0.0176 1005 10051 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.821 0.667 – 1.01 0.0632 101 1008 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.981 0.867 – 1.11 0.762 274 2756 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.951 0.836 – 1.08 0.449 259 2608 exclusion phecode
732 Osteochondropathies Musculoskeletal 1.01 0.915 – 1.1 0.906 466 4672 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.06 0.922 – 1.22 0.414 206 2065 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.874 0.664 – 1.15 0.335 57 569 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.02 0.971 – 1.07 0.449 1775 17793 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.19 1.07 – 1.34 0.00208 311 3114 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.01 0.922 – 1.1 0.888 540 5390 exclusion phecode
733.6 Costochondritis Musculoskeletal 1.09 0.913 – 1.31 0.328 128 1276 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.01 0.952 – 1.07 0.749 1231 12304 exclusion phecode
733.9 Chondromalacia Musculoskeletal 0.914 0.753 – 1.11 0.359 121 1206 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1 0.981 – 1.02 0.874 9593 95977 exclusion phecode
735.1 Flat foot Musculoskeletal 0.901 0.774 – 1.05 0.176 188 1908 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 0.993 0.964 – 1.02 0.613 5066 50665 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.993 0.947 – 1.04 0.777 1929 19310 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.972 0.922 – 1.02 0.286 1554 15514 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1 0.978 – 1.03 0.828 6637 66385 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1.05 0.996 – 1.1 0.0705 1625 16273 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.02 0.898 – 1.16 0.749 248 2474 exclusion phecode
737 Curvature of spine Musculoskeletal 1 0.944 – 1.07 0.926 1127 11285 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1 0.943 – 1.07 0.901 1060 10617 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.07 1.02 – 1.12 0.00382 1903 19038 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.09 1.03 – 1.15 0.00182 1512 15131 exclusion phecode
739 Contracture of joint Musculoskeletal 0.938 0.853 – 1.03 0.186 487 4880 exclusion phecode
740 Osteoarthrosis Musculoskeletal 0.996 0.983 – 1.01 0.491 27678 231416 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.99 0.974 – 1.01 0.198 17398 169270 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.994 0.973 – 1.02 0.609 8967 89672 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.956 0.856 – 1.07 0.426 348 3467 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.99 0.91 – 1.08 0.822 597 5966 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1 0.985 – 1.02 0.686 12254 122687 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.993 0.959 – 1.03 0.687 3561 35628 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.957 0.779 – 1.18 0.678 102 1018 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 0.961 0.884 – 1.04 0.347 613 6142 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.929 0.791 – 1.09 0.368 154 1540 exclusion phecode
741.4 Joint effusions Musculoskeletal 0.993 0.941 – 1.05 0.811 1417 14188 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 0.936 0.771 – 1.14 0.506 110 1099 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 1.33 1.02 – 1.74 0.0369 54 535 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.996 0.959 – 1.04 0.854 2843 28423 exclusion phecode
742.1 Loose body in joint Musculoskeletal 0.989 0.884 – 1.11 0.842 333 3336 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.961 0.779 – 1.19 0.71 95 959 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.06 0.971 – 1.16 0.188 500 4993 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.99 0.946 – 1.04 0.671 1993 19913 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.993 0.97 – 1.02 0.588 7552 75653 exclusion phecode
743.1 Osteoporosis Musculoskeletal 0.992 0.966 – 1.02 0.529 6395 64047 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 0.986 0.959 – 1.01 0.313 5544 55551 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1.08 0.988 – 1.18 0.0915 529 5280 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.05 0.963 – 1.15 0.251 510 5172 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.977 0.909 – 1.05 0.526 815 8137 exclusion phecode
745 Pain in joint Musculoskeletal 0.99 0.967 – 1.01 0.377 7965 79719 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.01 0.97 – 1.05 0.66 2797 28034 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.01 0.97 – 1.05 0.647 2624 26300 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.951 0.873 – 1.04 0.255 584 5831 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.959 0.836 – 1.1 0.552 235 2357 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.03 0.98 – 1.08 0.255 1813 18189 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.994 0.844 – 1.17 0.943 166 1680 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.01 0.759 – 1.35 0.939 51 510 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.04 0.929 – 1.17 0.467 301 3028 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.967 0.894 – 1.05 0.411 684 6858 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.988 0.882 – 1.11 0.834 326 3256 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.09 0.945 – 1.26 0.229 190 1906 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.917 0.821 – 1.02 0.122 355 3569 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.899 0.78 – 1.03 0.136 225 2253 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.962 0.798 – 1.16 0.686 116 1179 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.997 0.945 – 1.05 0.9 1525 15272 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.02 0.941 – 1.1 0.664 694 6924 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.992 0.902 – 1.09 0.863 455 4541 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.08 0.942 – 1.24 0.274 222 2215 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.984 0.915 – 1.06 0.653 834 8380 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.945 0.855 – 1.04 0.271 423 4244 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.06 0.943 – 1.18 0.342 332 3344 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.952 0.849 – 1.07 0.397 327 3301 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.02 0.897 – 1.16 0.774 252 2552 exclusion phecode
752.11 Spina bifida Congenital Anomalies 1.05 0.91 – 1.2 0.529 207 2103 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.796 0.621 – 1.02 0.0702 78 779 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.84 0.693 – 1.02 0.0774 127 1269 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.809 0.631 – 1.04 0.0964 76 760 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.13 0.927 – 1.37 0.231 108 1096 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.971 0.88 – 1.07 0.562 425 4269 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.996 0.864 – 1.15 0.953 208 2083 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.959 0.816 – 1.13 0.609 160 1618 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.964 0.794 – 1.17 0.713 106 1069 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.01 0.924 – 1.1 0.888 585 5866 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.06 0.852 – 1.32 0.599 81 810 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.963 0.872 – 1.06 0.459 435 4348 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1 0.846 – 1.18 0.994 147 1706 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 1 0.769 – 1.3 0.99 60 828 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.01 0.875 – 1.16 0.906 213 2158 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.02 0.824 – 1.27 0.838 95 957 exclusion phecode
760 Back pain Symptoms 0.99 0.971 – 1.01 0.334 11110 111245 exclusion phecode
761 Cervicalgia Symptoms 0.988 0.941 – 1.04 0.616 1788 17889 exclusion phecode
764 Sciatica Symptoms 0.976 0.935 – 1.02 0.253 2370 23708 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.979 0.921 – 1.04 0.493 1170 11731 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.05 0.973 – 1.14 0.198 631 6308 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.02 0.95 – 1.09 0.595 870 8681 exclusion phecode
771.1 Swelling of limb Symptoms 1 0.973 – 1.03 0.861 4613 46286 exclusion phecode
772 Symptoms of the muscles Symptoms 1.05 0.97 – 1.14 0.223 656 6574 exclusion phecode
773 Pain in limb Symptoms 0.994 0.969 – 1.02 0.666 6202 62140 exclusion phecode
780 Hypothermia/Chills Symptoms 0.99 0.847 – 1.16 0.896 171 1718 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.999 0.953 – 1.05 0.975 1867 18698 exclusion phecode
782.3 Edema Symptoms 0.988 0.939 – 1.04 0.637 1641 16442 exclusion phecode
782.6 Pallor and flushing Symptoms 0.906 0.776 – 1.06 0.215 175 1747 exclusion phecode
783 Fever of unknown origin Symptoms 1 0.967 – 1.03 0.988 3903 39077 exclusion phecode
785 Abdominal pain Symptoms 1.01 0.996 – 1.02 0.233 40035 301436 exclusion phecode
788 Syncope and collapse Symptoms 0.995 0.974 – 1.02 0.663 9057 90734 exclusion phecode
789 Nausea and vomiting Symptoms 1 0.985 – 1.02 0.659 11562 115700 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.01 0.853 – 1.19 0.932 149 1500 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 0.884 0.695 – 1.12 0.313 83 840 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 0.996 0.97 – 1.02 0.736 6347 63593 exclusion phecode
791 Gangrene Symptoms 0.985 0.902 – 1.08 0.738 547 5496 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.974 0.793 – 1.2 0.8 98 966 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.904 0.76 – 1.08 0.258 134 1338 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 0.977 0.897 – 1.06 0.584 565 5641 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.1 0.918 – 1.32 0.3 120 1196 exclusion phecode
797 Shock Symptoms 0.954 0.807 – 1.13 0.58 156 1559 exclusion phecode
797.1 Cardiogenic shock Symptoms 0.855 0.697 – 1.05 0.132 102 1019 exclusion phecode
798 Malaise and fatigue Symptoms 0.956 0.923 – 0.991 0.0142 3403 34080 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 0.996 0.916 – 1.08 0.919 591 5908 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.02 0.991 – 1.04 0.207 7031 70268 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.02 0.967 – 1.07 0.534 1814 18135 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.925 0.79 – 1.08 0.333 170 1692 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.01 0.965 – 1.05 0.703 2156 21558 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 1.04 0.965 – 1.12 0.319 766 7648 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1 0.96 – 1.05 0.872 2204 22021 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 0.992 0.945 – 1.04 0.739 1834 18330 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.03 0.951 – 1.11 0.501 718 7179 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 1 0.981 – 1.03 0.799 8281 82816 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 0.997 0.949 – 1.05 0.919 1690 16869 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.996 0.968 – 1.02 0.766 5210 52126 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.03 0.974 – 1.08 0.33 1517 15177 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 1.01 0.978 – 1.05 0.45 3337 33361 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1 0.946 – 1.06 0.994 1358 13555 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1 0.93 – 1.08 0.955 776 7750 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.993 0.938 – 1.05 0.813 1299 12990 exclusion phecode
817 Concussion Injuries & Poisonings 0.904 0.791 – 1.03 0.14 243 2426 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.936 0.855 – 1.02 0.152 521 5210 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.03 0.987 – 1.06 0.197 2955 29576 exclusion phecode
823 Torus fracture Injuries & Poisonings 1.02 0.971 – 1.07 0.428 1671 16696 exclusion phecode
830 Dislocation Injuries & Poisonings 1.02 0.974 – 1.06 0.421 2086 20854 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.986 0.97 – 1 0.0978 15210 152134 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.967 0.882 – 1.06 0.474 526 5262 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.961 0.874 – 1.06 0.417 469 4692 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.02 0.992 – 1.05 0.16 5246 52580 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.06 0.903 – 1.24 0.48 157 1566 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.07 0.974 – 1.17 0.167 499 5004 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1 0.953 – 1.05 0.988 1823 18228 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.02 0.963 – 1.08 0.491 1239 12409 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.994 0.958 – 1.03 0.732 3158 31577 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.02 0.983 – 1.06 0.308 3255 32577 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.01 0.801 – 1.27 0.936 68 680 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.01 0.973 – 1.04 0.681 3495 35036 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.08 0.955 – 1.22 0.224 272 2711 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1.05 0.909 – 1.21 0.515 196 1948 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.997 0.96 – 1.04 0.897 2898 29063 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.03 0.891 – 1.18 0.728 220 2198 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 1.06 0.816 – 1.37 0.665 68 678 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1 0.971 – 1.04 0.865 4061 40630 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.04 0.789 – 1.37 0.776 53 530 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.794 0.64 – 0.986 0.037 91 899 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.916 0.783 – 1.07 0.276 178 1785 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 0.88 0.799 – 0.969 0.00946 475 4738 exclusion phecode
873 Broken tooth Injuries & Poisonings 1.17 1.02 – 1.34 0.0232 228 2288 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.06 0.908 – 1.24 0.468 169 1708 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.07 0.914 – 1.26 0.384 156 1566 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.05 0.995 – 1.11 0.0754 1313 13134 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 0.993 0.962 – 1.02 0.64 4254 42615 exclusion phecode
916 Contusion Injuries & Poisonings 0.985 0.933 – 1.04 0.572 1447 14489 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.959 0.824 – 1.12 0.587 179 1804 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.992 0.896 – 1.1 0.885 388 3896 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.956 0.842 – 1.09 0.487 252 2527 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.981 0.937 – 1.03 0.401 2091 20944 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.986 0.86 – 1.13 0.843 225 2248 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.992 0.812 – 1.21 0.941 104 1037 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.04 0.951 – 1.13 0.401 549 5505 exclusion phecode
947 Urticaria Injuries & Poisonings 1.04 0.93 – 1.15 0.525 371 3701 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.01 0.912 – 1.12 0.814 397 3979 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.03 0.932 – 1.13 0.573 423 4220 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.07 0.948 – 1.22 0.263 269 2695 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.01 0.919 – 1.11 0.843 491 4923 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.12 0.865 – 1.45 0.39 55 554 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.01 0.8 – 1.29 0.904 74 740 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.01 0.992 – 1.02 0.369 18074 180988 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.01 0.993 – 1.03 0.274 15825 158486 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.03 0.93 – 1.13 0.601 420 4192 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.987 0.92 – 1.06 0.716 868 8691 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1 0.901 – 1.11 0.98 371 3704 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 0.992 0.891 – 1.1 0.884 363 3635 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.05 0.911 – 1.2 0.527 222 2223 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.01 0.891 – 1.14 0.905 282 2828 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.04 0.917 – 1.17 0.556 276 2768 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.996 0.97 – 1.02 0.742 6075 60820 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.975 0.917 – 1.04 0.411 1141 11441 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.03 0.94 – 1.13 0.511 476 4762 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.951 – 1.17 0.324 403 4042 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.04 0.949 – 1.14 0.409 510 5118 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.01 0.926 – 1.1 0.838 583 5839 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.01 0.965 – 1.06 0.656 1948 19504 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.06 0.918 – 1.23 0.415 190 1906 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1 0.884 – 1.14 0.976 271 2715 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.04 0.83 – 1.3 0.745 84 849 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 0.959 0.791 – 1.16 0.673 108 1078 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.16 0.944 – 1.42 0.159 101 1018 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.86 0.663 – 1.12 0.256 64 639 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.77 0.59 – 1 0.0541 58 580 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1 0.873 – 1.15 0.994 234 2336 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.01 0.932 – 1.09 0.876 697 6960 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.05 0.909 – 1.21 0.522 200 1998 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 0.785 0.594 – 1.04 0.0868 62 619 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.04 0.853 – 1.26 0.718 105 1049 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.936 0.771 – 1.14 0.5 111 1127 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.9 0.722 – 1.12 0.346 89 890 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1 0.965 – 1.04 0.964 3099 31115 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.01 0.969 – 1.04 0.767 3023 30240 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.01 0.969 – 1.04 0.767 3023 30240 exclusion phecode
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