Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Non-Hodgkin lymphoma UK Biobank (UKB) PheWAS analysis

Non-Hodgkin lymphoma — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID prsweb-phecode202-2-gwas-catalog-r2019-05-03-x202-2-p-5e-08-ukb-20200608Legacy P_5e-08GWAS HitsGWAS Catalog (2019-05-03)

Evaluation cohort: UK Biobank (UKB).

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108 rows visible 16 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 0.994 0.973 – 1.02 0.616 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.04 0.996 – 1.08 0.0823 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.04 0.961 – 1.13 0.329 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 0.973 0.907 – 1.04 0.444 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.26 0.974 – 1.62 0.0786 55 550 all phecode
010 Tuberculosis Infectious Diseases 0.985 0.839 – 1.16 0.856 166 1659 all phecode
038 Septicemia Infectious Diseases 0.981 0.95 – 1.01 0.238 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 0.957 0.892 – 1.03 0.226 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 0.987 0.9 – 1.08 0.772 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 0.981 0.963 – 1 0.0468 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 0.971 0.935 – 1.01 0.114 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 1.05 1 – 1.11 0.0387 1641 16433 all phecode
041.4 E. coli Infectious Diseases 0.973 0.936 – 1.01 0.181 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 1.06 0.961 – 1.18 0.233 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.15 0.932 – 1.42 0.192 95 949 all phecode
054 Herpes simplex Infectious Diseases 1.04 0.901 – 1.19 0.623 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 1.03 0.95 – 1.12 0.462 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 1.11 0.878 – 1.41 0.377 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.04 0.877 – 1.23 0.657 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.05 0.927 – 1.2 0.424 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 0.967 0.853 – 1.1 0.602 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.01 0.914 – 1.11 0.863 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.16 0.986 – 1.36 0.0739 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.21 1.01 – 1.44 0.0426 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 0.971 0.91 – 1.04 0.375 1004 10036 all phecode
079 Viral infection Infectious Diseases 1 0.965 – 1.04 0.853 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 0.992 0.774 – 1.27 0.947 64 640 all phecode
080 Postoperative infection Infectious Diseases 0.985 0.955 – 1.02 0.336 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 0.971 0.931 – 1.01 0.16 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.84 0.656 – 1.08 0.167 71 709 all phecode
1000 Burns Injuries & Poisonings 1.04 0.957 – 1.14 0.335 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 0.991 0.934 – 1.05 0.771 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.02 0.99 – 1.05 0.208 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 0.97 0.861 – 1.09 0.612 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 1.02 0.968 – 1.08 0.439 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 1.14 1.01 – 1.3 0.0344 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 0.976 0.859 – 1.11 0.711 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.01 0.95 – 1.08 0.7 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 0.985 0.963 – 1.01 0.185 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 0.995 0.969 – 1.02 0.727 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1 0.98 – 1.02 0.928 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 1.19 0.982 – 1.44 0.0758 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.1 0.979 – 1.23 0.112 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.919 0.715 – 1.18 0.507 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 0.992 0.961 – 1.02 0.619 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.01 0.989 – 1.02 0.511 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.915 0.808 – 1.04 0.161 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 0.93 0.82 – 1.05 0.257 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.841 0.66 – 1.07 0.164 74 756 all phecode
110.12 Althete's foot Infectious Diseases 0.899 0.754 – 1.07 0.237 141 1410 all phecode
112 Candidiasis Infectious Diseases 0.968 0.925 – 1.01 0.153 2126 21275 all phecode
117 Mycoses Infectious Diseases 1.04 0.923 – 1.17 0.513 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 1.03 0.878 – 1.2 0.75 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 0.965 0.774 – 1.2 0.748 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 0.962 0.756 – 1.22 0.753 69 689 all phecode
134 Helminthiases Infectious Diseases 0.839 0.692 – 1.02 0.0714 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 0.819 0.666 – 1.01 0.0588 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.04 0.903 – 1.2 0.578 205 2050 all phecode
145 Cancer of mouth Neoplasms 1.02 0.943 – 1.1 0.615 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 1.06 0.943 – 1.19 0.336 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.04 0.854 – 1.26 0.714 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 0.994 0.759 – 1.3 0.964 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.06 0.974 – 1.14 0.186 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 1.11 0.98 – 1.26 0.0993 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 1.01 0.893 – 1.15 0.847 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 1.01 0.777 – 1.32 0.921 57 570 all phecode
150 Cancer of esophagus Neoplasms 0.982 0.912 – 1.06 0.631 762 7630 all phecode
151 Cancer of stomach Neoplasms 1.05 0.961 – 1.14 0.298 569 5696 all phecode
153 Colorectal cancer Neoplasms 0.988 0.959 – 1.02 0.445 4580 45799 all phecode
153.2 Colon cancer Neoplasms 0.997 0.96 – 1.03 0.854 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.972 0.93 – 1.02 0.219 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.92 0.827 – 1.02 0.128 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.92 0.778 – 1.09 0.333 158 1580 all phecode
157 Pancreatic cancer Neoplasms 0.986 0.91 – 1.07 0.731 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.02 0.956 – 1.08 0.581 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.988 0.961 – 1.02 0.387 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.975 0.839 – 1.13 0.737 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.07 0.926 – 1.23 0.374 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1 0.864 – 1.17 0.965 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 1.29 1.01 – 1.65 0.0439 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 0.959 0.922 – 0.997 0.0332 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 0.929 0.889 – 0.971 0.00113 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 1.03 0.932 – 1.13 0.589 437 4364 all phecode
170.1 Bone cancer Neoplasms 1.04 0.872 – 1.25 0.642 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 1.01 0.9 – 1.12 0.923 331 3303 all phecode
172 Skin cancer Neoplasms 1.02 1 – 1.04 0.0196 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.972 0.934 – 1.01 0.16 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 0.972 0.934 – 1.01 0.153 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1.04 1.02 – 1.06 0.000181 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 0.937 0.865 – 1.02 0.113 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.05 0.899 – 1.22 0.552 181 1818 all phecode
174 Breast cancer Neoplasms 1.01 0.993 – 1.03 0.24 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 1.01 0.993 – 1.03 0.232 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.01 0.994 – 1.03 0.178 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.07 0.886 – 1.28 0.496 115 1148 all phecode
175 Acquired absence of breast Neoplasms 1 0.963 – 1.05 0.842 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 0.96 0.918 – 1 0.07 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 0.943 0.834 – 1.07 0.354 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.963 0.921 – 1.01 0.108 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 1 0.946 – 1.06 0.944 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 0.974 0.922 – 1.03 0.357 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.96 0.898 – 1.03 0.224 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.966 0.903 – 1.03 0.31 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.969 0.859 – 1.09 0.6 305 3049 all phecode
185 Cancer of prostate Neoplasms 0.998 0.972 – 1.03 0.887 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 1.03 0.934 – 1.13 0.559 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.967 0.76 – 1.23 0.784 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 1.06 0.945 – 1.2 0.304 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.982 0.807 – 1.19 0.855 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.984 0.953 – 1.02 0.327 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.981 0.922 – 1.04 0.552 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.968 0.908 – 1.03 0.32 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.14 0.882 – 1.47 0.318 66 660 all phecode
189.2 Cancer of bladder Neoplasms 0.974 0.934 – 1.02 0.228 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.977 0.934 – 1.02 0.306 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.01 0.85 – 1.19 0.94 144 1439 all phecode
190 Cancer of eye Neoplasms 0.962 0.823 – 1.12 0.622 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.989 0.915 – 1.07 0.787 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 0.954 0.874 – 1.04 0.291 566 5650 all phecode
191.11 Cancer of brain Neoplasms 0.95 0.867 – 1.04 0.267 525 5240 all phecode
193 Thyroid cancer Neoplasms 1.14 1.02 – 1.27 0.0196 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 1.02 0.833 – 1.25 0.835 95 949 all phecode
195 Cancer, suspected or other Neoplasms 1.01 0.992 – 1.02 0.313 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.01 0.993 – 1.03 0.278 16267 159497 all phecode
197 Chemotherapy Neoplasms 1.02 1 – 1.03 0.0303 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 0.983 0.962 – 1 0.11 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.996 0.969 – 1.02 0.799 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.973 0.932 – 1.02 0.215 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.967 0.918 – 1.02 0.208 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 0.948 0.91 – 0.986 0.00863 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.926 0.863 – 0.993 0.0321 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 0.975 0.933 – 1.02 0.26 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.02 0.882 – 1.18 0.772 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 0.984 0.932 – 1.04 0.571 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 1.1 0.905 – 1.34 0.332 95 950 all phecode
200 Myeloproliferative disease Neoplasms 0.979 0.918 – 1.04 0.517 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 0.957 0.864 – 1.06 0.408 387 3867 all phecode
201 Hodgkin's disease Neoplasms 1.06 0.936 – 1.21 0.34 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.14 1.1 – 1.19 4.65e-10 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.2 1.14 – 1.25 4.57e-14 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 1.6 1.44 – 1.77 1.41e-18 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 1.2 1.1 – 1.3 1.55e-05 581 5824 all phecode
204 Leukemia Neoplasms 1.02 0.967 – 1.07 0.524 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 1.07 0.986 – 1.17 0.1 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.997 0.756 – 1.31 0.983 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.09 0.994 – 1.19 0.0686 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 0.998 0.908 – 1.1 0.969 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.955 0.854 – 1.07 0.425 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.1 0.922 – 1.3 0.297 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 1.01 0.923 – 1.1 0.883 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 1 0.987 – 1.02 0.821 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.952 0.891 – 1.02 0.144 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.01 0.977 – 1.03 0.702 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.04 0.931 – 1.16 0.506 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.945 0.842 – 1.06 0.343 318 3187 all phecode
214 Lipoma Neoplasms 1.02 0.989 – 1.04 0.26 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.03 1 – 1.06 0.0468 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.01 0.954 – 1.08 0.657 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 1.01 0.989 – 1.04 0.315 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.04 0.957 – 1.13 0.367 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.03 0.95 – 1.12 0.444 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 0.997 0.976 – 1.02 0.749 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 1 0.98 – 1.02 0.972 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.982 0.881 – 1.09 0.74 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 0.936 0.886 – 0.989 0.0178 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.01 0.878 – 1.16 0.909 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 1.1 0.943 – 1.29 0.221 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.991 0.846 – 1.16 0.909 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 1.14 0.95 – 1.36 0.161 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.3 1.02 – 1.66 0.0346 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.949 0.882 – 1.02 0.153 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.961 0.893 – 1.04 0.297 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.784 0.601 – 1.02 0.0732 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.16 1.03 – 1.31 0.0151 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.994 0.927 – 1.07 0.865 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.09 0.942 – 1.26 0.25 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.979 0.881 – 1.09 0.7 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.958 0.852 – 1.08 0.478 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.03 0.983 – 1.09 0.192 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.993 0.952 – 1.04 0.749 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.963 0.887 – 1.05 0.379 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.941 0.884 – 1 0.0541 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.01 0.918 – 1.11 0.874 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.902 0.832 – 0.978 0.0121 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.975 0.929 – 1.02 0.297 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 0.927 0.842 – 1.02 0.122 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.05 0.85 – 1.29 0.662 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 0.99 0.829 – 1.18 0.912 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 1.01 0.991 – 1.03 0.354 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.974 0.915 – 1.04 0.397 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.11 0.912 – 1.36 0.289 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.01 0.992 – 1.03 0.305 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 0.97 0.86 – 1.09 0.614 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.01 0.881 – 1.16 0.88 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.04 0.903 – 1.19 0.613 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 0.999 0.903 – 1.11 0.992 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.01 0.998 – 1.03 0.0987 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.01 0.974 – 1.05 0.51 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.971 0.848 – 1.11 0.672 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.13 0.901 – 1.41 0.291 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.08 0.988 – 1.19 0.0886 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.06 0.903 – 1.25 0.46 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.01 0.998 – 1.03 0.0868 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.936 0.768 – 1.14 0.513 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.06 0.918 – 1.22 0.429 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.06 0.99 – 1.13 0.0961 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 0.981 0.895 – 1.07 0.677 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 0.978 0.905 – 1.06 0.574 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.01 0.894 – 1.14 0.877 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.971 0.879 – 1.07 0.57 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.01 0.844 – 1.2 0.939 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.996 0.891 – 1.11 0.949 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.06 0.997 – 1.12 0.0612 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.04 0.975 – 1.12 0.222 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.995 0.928 – 1.07 0.895 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.998 0.927 – 1.07 0.955 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.1 0.928 – 1.31 0.265 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.983 0.909 – 1.06 0.676 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.868 0.744 – 1.01 0.0696 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.826 0.663 – 1.03 0.0876 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.03 0.912 – 1.17 0.598 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.07 0.863 – 1.31 0.556 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.931 0.792 – 1.1 0.391 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.952 0.878 – 1.03 0.243 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.06 0.908 – 1.23 0.479 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.03 0.839 – 1.26 0.781 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.12 0.893 – 1.4 0.333 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.887 0.794 – 0.991 0.0344 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.889 0.795 – 0.993 0.0375 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 0.93 0.814 – 1.06 0.285 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.908 0.786 – 1.05 0.189 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 1.16 0.993 – 1.35 0.0618 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.13 0.961 – 1.32 0.143 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.972 0.802 – 1.18 0.768 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.01 0.858 – 1.19 0.897 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.06 0.917 – 1.22 0.436 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 1.31 0.971 – 1.75 0.0781 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 1.02 0.95 – 1.1 0.588 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 0.972 0.916 – 1.03 0.347 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.963 0.893 – 1.04 0.328 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.996 0.904 – 1.1 0.928 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.01 0.804 – 1.27 0.921 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1 0.879 – 1.14 0.997 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 1.05 0.938 – 1.17 0.4 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.06 0.943 – 1.18 0.349 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.11 0.988 – 1.26 0.079 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.07 0.932 – 1.24 0.329 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 0.901 0.739 – 1.1 0.3 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.35 1.06 – 1.71 0.0133 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.883 0.749 – 1.04 0.138 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.836 0.7 – 0.999 0.0486 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.01 1 – 1.02 0.0508 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.01 1 – 1.02 0.0532 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.01 1 – 1.02 0.051 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.27 0.978 – 1.66 0.0727 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.888 0.753 – 1.05 0.16 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.977 0.848 – 1.13 0.746 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.994 0.961 – 1.03 0.724 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 1 0.964 – 1.04 0.983 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.994 0.821 – 1.2 0.949 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.957 0.88 – 1.04 0.304 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.937 0.858 – 1.02 0.15 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.98 0.937 – 1.02 0.374 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.923 0.851 – 1 0.0543 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.11 0.996 – 1.23 0.0604 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.992 0.935 – 1.05 0.791 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.13 0.968 – 1.33 0.12 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 0.981 0.958 – 1.01 0.126 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 0.985 0.953 – 1.02 0.347 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.989 0.865 – 1.13 0.874 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.02 0.968 – 1.07 0.525 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 0.968 0.906 – 1.03 0.34 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 0.967 0.916 – 1.02 0.235 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.993 0.935 – 1.06 0.829 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 1 0.939 – 1.07 0.993 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 0.848 0.694 – 1.04 0.105 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 0.975 0.938 – 1.01 0.205 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 0.901 0.817 – 0.993 0.0361 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 1.14 0.956 – 1.35 0.147 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.01 0.94 – 1.08 0.86 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.11 0.999 – 1.23 0.0516 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.979 0.851 – 1.13 0.768 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.08 0.817 – 1.43 0.58 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.994 0.974 – 1.01 0.538 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 0.993 0.974 – 1.01 0.514 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 0.914 0.733 – 1.14 0.427 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.969 0.746 – 1.26 0.812 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.04 0.918 – 1.19 0.509 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1.09 0.943 – 1.25 0.252 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.11 0.931 – 1.32 0.248 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.01 0.884 – 1.15 0.924 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 0.963 0.941 – 0.986 0.00201 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.964 0.941 – 0.987 0.00282 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.967 0.878 – 1.06 0.497 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 0.935 0.879 – 0.994 0.0307 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 0.935 0.878 – 0.996 0.0358 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 0.957 0.889 – 1.03 0.242 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.947 0.809 – 1.11 0.493 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 0.888 0.762 – 1.04 0.13 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 1.01 0.775 – 1.32 0.942 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.08 0.92 – 1.27 0.343 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1 0.771 – 1.31 0.974 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.14 0.918 – 1.41 0.242 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.03 0.87 – 1.23 0.7 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.952 0.777 – 1.17 0.632 103 1059 all phecode
284 Aplastic anemia Hematopoietic 1.06 0.961 – 1.17 0.245 435 4357 all phecode
285 Other anemias Hematopoietic 0.999 0.981 – 1.02 0.945 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.08 0.957 – 1.23 0.206 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 0.989 0.915 – 1.07 0.775 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1 0.904 – 1.11 0.997 414 4147 all phecode
286 Coagulation defects Hematopoietic 0.984 0.919 – 1.05 0.632 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 0.958 0.87 – 1.05 0.376 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 0.921 0.748 – 1.13 0.437 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.961 0.851 – 1.08 0.516 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 0.993 0.773 – 1.28 0.955 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.911 0.732 – 1.13 0.406 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.01 0.911 – 1.13 0.808 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.968 0.92 – 1.02 0.209 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.12 0.937 – 1.33 0.218 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 1.04 0.781 – 1.37 0.808 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 0.963 0.914 – 1.02 0.162 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 0.953 0.861 – 1.05 0.346 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.03 0.818 – 1.3 0.803 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 1.03 0.994 – 1.06 0.114 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 1.05 1.01 – 1.09 0.00955 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 1.05 1.01 – 1.09 0.0128 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 1.29 1.02 – 1.64 0.0348 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.979 0.913 – 1.05 0.555 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.876 0.775 – 0.989 0.0331 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 1.03 0.989 – 1.07 0.15 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 1.01 0.92 – 1.1 0.897 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.03 0.914 – 1.16 0.641 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 0.965 0.778 – 1.2 0.749 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.968 0.924 – 1.01 0.177 1929 19281 all phecode
290.1 Dementias Mental Disorders 0.965 0.905 – 1.03 0.278 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 0.953 0.863 – 1.05 0.344 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 0.919 0.793 – 1.07 0.264 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.999 0.921 – 1.08 0.972 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.852 0.667 – 1.09 0.2 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.991 0.924 – 1.06 0.807 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.993 0.838 – 1.18 0.933 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.01 0.892 – 1.14 0.908 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 1.01 0.912 – 1.11 0.906 436 4376 all phecode
292 Neurological disorders Mental Disorders 0.983 0.954 – 1.01 0.27 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.03 0.978 – 1.09 0.251 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 1.05 0.907 – 1.22 0.497 190 1907 all phecode
292.3 Memory loss Mental Disorders 0.954 0.882 – 1.03 0.235 696 6978 all phecode
292.4 Altered mental status Mental Disorders 0.964 0.922 – 1.01 0.101 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 0.946 0.84 – 1.07 0.36 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 1.02 0.972 – 1.06 0.481 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.996 0.93 – 1.07 0.914 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.04 0.968 – 1.11 0.292 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 1.05 0.963 – 1.14 0.272 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 1.03 0.886 – 1.21 0.669 178 1780 all phecode
295.3 Psychosis Mental Disorders 1.02 0.869 – 1.19 0.839 169 1710 all phecode
296 Mood disorders Mental Disorders 1 0.982 – 1.02 0.991 12372 123822 all phecode
296.1 Bipolar Mental Disorders 1.01 0.945 – 1.07 0.86 1059 10599 all phecode
296.2 Depression Mental Disorders 1 0.983 – 1.02 0.861 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 0.96 0.862 – 1.07 0.45 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.03 0.918 – 1.16 0.603 311 3070 all phecode
300 Anxiety disorders Mental Disorders 0.97 0.946 – 0.994 0.0163 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 0.969 0.944 – 0.994 0.0157 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 0.968 0.82 – 1.14 0.702 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.01 0.939 – 1.09 0.718 707 7065 all phecode
300.13 Phobia Mental Disorders 0.891 0.812 – 0.979 0.0159 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.949 0.801 – 1.13 0.549 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 1.2 0.917 – 1.57 0.185 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 0.939 0.785 – 1.12 0.492 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.04 0.858 – 1.27 0.663 113 1129 all phecode
301 Personality disorders Mental Disorders 0.995 0.891 – 1.11 0.924 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.12 0.936 – 1.34 0.213 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 1.01 0.889 – 1.14 0.922 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.995 0.904 – 1.1 0.919 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 1.02 0.917 – 1.14 0.668 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 0.956 0.794 – 1.15 0.636 123 1229 all phecode
304 Adjustment reaction Mental Disorders 1.06 0.942 – 1.19 0.33 293 2936 all phecode
305.2 Eating disorder Mental Disorders 1.08 0.875 – 1.34 0.468 90 900 all phecode
306 Other mental disorder Mental Disorders 0.986 0.974 – 0.998 0.0278 28056 230087 all phecode
306.9 Tension headache Mental Disorders 0.935 0.83 – 1.05 0.261 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 1.04 0.827 – 1.31 0.74 76 770 all phecode
313.3 Autism Mental Disorders 0.995 0.761 – 1.3 0.971 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 0.982 0.881 – 1.09 0.741 351 3517 all phecode
315.1 Learning disorder Mental Disorders 1.08 0.923 – 1.27 0.33 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 0.929 0.743 – 1.16 0.516 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 1.02 0.988 – 1.04 0.277 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.85 0.648 – 1.12 0.242 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 0.987 0.969 – 1.01 0.174 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 0.976 0.954 – 0.997 0.0263 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.02 0.95 – 1.09 0.596 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 0.986 0.971 – 1 0.058 19359 185465 all phecode
320 Meningitis Neurological 0.984 0.891 – 1.09 0.75 444 4447 all phecode
323 Encephalitis Neurological 0.914 0.818 – 1.02 0.113 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 0.844 0.673 – 1.06 0.142 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 1 0.89 – 1.13 0.955 292 2916 all phecode
327 Sleep disorders Neurological 1.03 0.973 – 1.09 0.299 1164 11659 all phecode
327.3 Sleep apnea Neurological 1.01 0.976 – 1.04 0.702 4428 44318 all phecode
327.4 Insomnia Neurological 1.08 0.928 – 1.26 0.316 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 1.1 0.928 – 1.3 0.275 136 1390 all phecode
331 Other cerebral degenerations Neurological 0.959 0.902 – 1.02 0.184 1142 11416 all phecode
331.1 Hydrocephalus Neurological 0.93 0.848 – 1.02 0.122 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 0.974 0.881 – 1.08 0.599 430 4298 all phecode
332 Parkinson's disease Neurological 0.952 0.895 – 1.01 0.112 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.02 0.949 – 1.09 0.657 894 8954 all phecode
333.1 Essential tremor Neurological 0.996 0.867 – 1.14 0.955 216 2157 all phecode
333.2 Myoclonus Neurological 1.05 0.857 – 1.29 0.627 96 958 all phecode
333.4 Torsion dystonia Neurological 1.05 0.924 – 1.2 0.44 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 0.96 0.915 – 1.01 0.098 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 0.969 0.8 – 1.17 0.746 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 0.921 0.806 – 1.05 0.23 245 2446 all phecode
335 Multiple sclerosis Neurological 0.783 0.738 – 0.83 3.44e-16 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 0.98 0.864 – 1.11 0.756 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.16 0.929 – 1.44 0.191 72 719 all phecode
338 Pain Neurological 0.989 0.918 – 1.07 0.767 768 7692 all phecode
338.1 Acute pain Neurological 0.961 0.866 – 1.07 0.459 394 3937 all phecode
338.2 Chronic pain Neurological 0.978 0.88 – 1.09 0.68 380 3817 all phecode
339 Other headache syndromes Neurological 1.01 0.986 – 1.03 0.465 7819 78241 all phecode
340 Migraine Neurological 0.983 0.946 – 1.02 0.384 2860 28602 all phecode
340.1 Migrain with aura Neurological 0.943 0.817 – 1.09 0.423 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.887 0.776 – 1.01 0.0796 252 2535 all phecode
342 Hemiplegia Neurological 0.973 0.923 – 1.03 0.315 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 1.1 0.933 – 1.3 0.252 145 1450 all phecode
344 Other paralytic syndromes Neurological 0.918 0.847 – 0.996 0.0408 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.989 0.961 – 1.02 0.448 5023 50270 all phecode
345.1 Epilepsy Neurological 0.974 0.908 – 1.05 0.463 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 1.03 0.938 – 1.14 0.497 439 4385 all phecode
345.12 Partial epilepsy Neurological 0.965 0.852 – 1.09 0.576 277 2776 all phecode
345.3 Convulsions Neurological 0.994 0.952 – 1.04 0.784 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.04 0.875 – 1.23 0.674 144 1438 all phecode
348 Other conditions of brain Neurological 0.939 0.872 – 1.01 0.0956 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 0.952 0.838 – 1.08 0.446 268 2678 all phecode
348.4 Cerebral cysts Neurological 0.956 0.803 – 1.14 0.617 133 1350 all phecode
348.7 Coma Neurological 0.944 0.847 – 1.05 0.293 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 0.993 0.873 – 1.13 0.92 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 0.995 0.899 – 1.1 0.927 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.914 0.816 – 1.02 0.121 342 3414 all phecode
350 Abnormal movement Neurological 0.996 0.958 – 1.04 0.861 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 1.01 0.938 – 1.08 0.871 887 8852 all phecode
350.2 Abnormality of gait Neurological 1.01 0.956 – 1.06 0.799 1596 15969 all phecode
350.3 Lack of coordination Neurological 1 0.899 – 1.11 0.998 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.02 0.769 – 1.35 0.888 54 540 all phecode
351 Other peripheral nerve disorders Neurological 0.996 0.978 – 1.01 0.701 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 1.04 0.982 – 1.1 0.186 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.03 0.939 – 1.13 0.526 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.01 0.941 – 1.08 0.826 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 0.947 0.89 – 1.01 0.0804 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 0.957 0.79 – 1.16 0.656 114 1138 all phecode
353.2 Nerve root lesions Neurological 1.04 0.806 – 1.34 0.76 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.22 1.05 – 1.43 0.0117 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.07 1.01 – 1.13 0.0245 1361 13648 all phecode
358 Myoneural disorders Neurological 1.14 0.986 – 1.31 0.0782 211 2109 all phecode
358.1 Myasthenia gravis Neurological 1.2 1.04 – 1.39 0.0149 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 1.05 0.95 – 1.15 0.358 465 4646 all phecode
359.1 Muscular dystrophies Neurological 1.02 0.846 – 1.24 0.82 122 1219 all phecode
359.2 Myopathy Neurological 1.05 0.94 – 1.17 0.397 360 3597 all phecode
360 Disorders of the globe Sense Organs 1 0.896 – 1.12 0.973 337 3367 all phecode
360.2 Progressive myopia Sense Organs 0.995 0.876 – 1.13 0.942 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 1 0.965 – 1.04 0.985 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 1 0.949 – 1.06 0.909 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.905 0.708 – 1.16 0.424 68 680 all phecode
362 Other retinal disorders Sense Organs 0.974 0.942 – 1.01 0.125 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.977 0.934 – 1.02 0.294 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.978 0.935 – 1.02 0.319 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.01 0.853 – 1.19 0.949 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 1.01 0.82 – 1.24 0.927 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.954 0.888 – 1.02 0.196 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.926 0.794 – 1.08 0.325 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.11 0.899 – 1.38 0.324 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.886 0.727 – 1.08 0.231 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.987 0.844 – 1.16 0.875 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 1.09 0.835 – 1.42 0.535 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.02 0.942 – 1.11 0.608 647 6485 all phecode
364.1 Corneal opacity Sense Organs 1.13 0.917 – 1.39 0.253 90 910 all phecode
364.2 Corneal edema Sense Organs 0.862 0.687 – 1.08 0.202 79 800 all phecode
364.4 Corneal degenerations Sense Organs 0.945 0.817 – 1.09 0.442 201 2017 all phecode
364.41 Keratoconus Sense Organs 0.789 0.628 – 0.99 0.0408 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 1.02 0.886 – 1.18 0.774 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 1.03 0.844 – 1.26 0.751 100 1000 all phecode
365 Glaucoma Sense Organs 1.02 0.986 – 1.05 0.288 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 1.01 0.943 – 1.07 0.874 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 1 0.941 – 1.07 0.934 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.02 0.941 – 1.1 0.696 698 6996 all phecode
366 Cataract Sense Organs 1.01 0.993 – 1.02 0.3 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 0.955 0.75 – 1.22 0.711 69 700 all phecode
366.2 Senile cataract Sense Organs 1 0.98 – 1.03 0.841 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 1.03 0.84 – 1.25 0.799 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.996 0.955 – 1.04 0.846 2408 24092 all phecode
367.1 Myopia Sense Organs 0.959 0.904 – 1.02 0.164 1251 12519 all phecode
367.2 Astigmatism Sense Organs 0.884 0.759 – 1.03 0.113 190 1899 all phecode
367.8 Hypermetropia Sense Organs 1.1 0.967 – 1.25 0.146 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 1.01 0.939 – 1.09 0.726 719 7198 all phecode
368 Visual disturbances Sense Organs 0.989 0.953 – 1.03 0.584 2962 29648 all phecode
368.1 Amblyopia Sense Organs 0.953 0.87 – 1.04 0.308 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.05 0.973 – 1.13 0.211 727 7288 all phecode
368.3 Anisometropia Sense Organs 0.984 0.832 – 1.16 0.846 154 1548 all phecode
368.4 Visual field defects Sense Organs 1.09 0.978 – 1.22 0.118 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 0.932 0.857 – 1.01 0.104 612 6115 all phecode
369 Infection of the eye Sense Organs 1.02 0.938 – 1.12 0.596 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 1.08 0.901 – 1.29 0.411 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 1.08 0.938 – 1.24 0.291 213 2128 all phecode
370 Keratitis Sense Organs 0.994 0.882 – 1.12 0.919 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 0.952 0.804 – 1.13 0.564 141 1408 all phecode
371 Inflammation of the eye Sense Organs 1 0.966 – 1.04 0.87 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.06 0.963 – 1.16 0.252 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 0.993 0.952 – 1.04 0.754 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 0.998 0.927 – 1.07 0.956 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 0.997 0.97 – 1.02 0.833 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 1 0.939 – 1.06 0.999 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 0.985 0.939 – 1.03 0.549 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 1.04 0.992 – 1.08 0.113 2204 22031 all phecode
375.2 Epiphora Sense Organs 1.04 0.971 – 1.11 0.263 898 8969 all phecode
376 Disorders of the orbit Sense Organs 0.903 0.724 – 1.13 0.37 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.842 0.752 – 0.941 0.00255 361 3618 all phecode
377.1 Optic atrophy Sense Organs 0.924 0.703 – 1.21 0.57 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.808 0.668 – 0.977 0.0276 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.01 0.959 – 1.07 0.657 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.985 0.92 – 1.05 0.658 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.04 0.905 – 1.19 0.588 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 1.09 0.967 – 1.22 0.163 275 2755 all phecode
379 Other disorders of eye Sense Organs 1 0.967 – 1.03 0.984 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 1.01 0.958 – 1.07 0.641 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.965 0.919 – 1.01 0.154 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.12 0.873 – 1.43 0.381 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.1 0.989 – 1.21 0.0817 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.919 0.787 – 1.07 0.288 169 1690 all phecode
380 Disorders of external ear Sense Organs 0.984 0.907 – 1.07 0.699 642 6413 all phecode
380.1 Otitis externa Sense Organs 0.973 0.887 – 1.07 0.561 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 0.992 0.892 – 1.1 0.889 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.03 0.985 – 1.08 0.192 2150 21493 all phecode
381.1 Otitis media Sense Organs 1.03 0.98 – 1.08 0.259 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1 0.937 – 1.08 0.907 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 1.09 0.944 – 1.26 0.237 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.02 0.866 – 1.19 0.853 171 1709 all phecode
381.9 Otorrhea Sense Organs 0.96 0.849 – 1.09 0.511 281 2807 all phecode
382 Otalgia Sense Organs 1.15 1.03 – 1.29 0.0161 308 3084 all phecode
383 Otosclerosis Sense Organs 0.894 0.794 – 1.01 0.0648 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.06 1 – 1.12 0.0462 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.03 0.966 – 1.1 0.379 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1 0.932 – 1.08 0.941 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 0.996 0.916 – 1.08 0.921 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.03 0.907 – 1.17 0.638 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.979 0.932 – 1.03 0.406 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 0.927 0.851 – 1.01 0.0846 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 1.04 0.939 – 1.15 0.445 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 0.979 0.909 – 1.06 0.582 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.993 0.963 – 1.02 0.636 4582 45806 all phecode
388 Other disorders of ear Sense Organs 0.966 0.838 – 1.11 0.633 202 2017 all phecode
389 Hearing loss Sense Organs 1.01 0.975 – 1.04 0.688 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 1.04 0.949 – 1.15 0.375 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 1.01 0.914 – 1.11 0.89 450 4497 all phecode
389.4 Tinnitus Sense Organs 1 0.914 – 1.1 0.988 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.01 0.977 – 1.04 0.7 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 1.01 0.973 – 1.05 0.616 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 1.02 0.968 – 1.08 0.399 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 0.973 0.913 – 1.04 0.394 1058 10566 all phecode
395 Heart valve disorders Circulatory System 0.983 0.952 – 1.01 0.284 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.991 0.954 – 1.03 0.655 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.993 0.88 – 1.12 0.906 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.13 0.923 – 1.38 0.235 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.907 0.735 – 1.12 0.363 97 970 all phecode
395.6 Heart valve replaced Circulatory System 0.996 0.944 – 1.05 0.872 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 0.994 0.933 – 1.06 0.84 1048 10468 all phecode
401 Hypertension Circulatory System 0.998 0.99 – 1.01 0.707 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 0.998 0.99 – 1.01 0.717 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 0.978 0.933 – 1.03 0.362 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 0.964 0.866 – 1.07 0.5 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.975 0.925 – 1.03 0.339 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 0.907 0.767 – 1.07 0.256 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 0.972 0.921 – 1.03 0.301 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 0.999 0.987 – 1.01 0.899 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1 0.976 – 1.03 0.768 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 0.999 0.98 – 1.02 0.877 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 1 0.987 – 1.02 0.719 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 1 0.989 – 1.02 0.602 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.01 0.93 – 1.09 0.886 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.994 0.978 – 1.01 0.505 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.979 0.922 – 1.04 0.478 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 0.989 0.943 – 1.04 0.658 1823 18228 all phecode
414.2 ASCVD Circulatory System 1.12 0.881 – 1.42 0.361 72 719 all phecode
415 Pulmonary heart disease Circulatory System 0.999 0.969 – 1.03 0.971 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.958 0.761 – 1.21 0.717 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.02 0.938 – 1.11 0.657 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.01 0.92 – 1.11 0.811 448 4475 all phecode
416 Cardiomegaly Circulatory System 0.971 0.933 – 1.01 0.147 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 1 0.989 – 1.01 0.831 28599 270106 all phecode
418.1 Precordial pain Circulatory System 1.01 0.973 – 1.04 0.679 3551 35541 all phecode
420 Carditis Circulatory System 0.97 0.927 – 1.01 0.178 2106 21053 all phecode
420.1 Myocarditis Circulatory System 0.911 0.761 – 1.09 0.31 127 1267 all phecode
420.2 Pericarditis Circulatory System 0.973 0.919 – 1.03 0.337 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 1.02 0.891 – 1.17 0.759 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 1.09 0.904 – 1.32 0.36 113 1129 all phecode
420.3 Endocarditis Circulatory System 1 0.927 – 1.08 0.987 719 7194 all phecode
425 Cardiomyopathy Circulatory System 0.97 0.914 – 1.03 0.306 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.97 0.914 – 1.03 0.322 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.07 0.894 – 1.27 0.468 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.11 0.944 – 1.3 0.207 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 1.04 0.798 – 1.37 0.754 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 0.998 0.974 – 1.02 0.888 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 0.992 0.948 – 1.04 0.736 2114 21162 all phecode
426.21 First degree AV block Circulatory System 1.01 0.947 – 1.08 0.717 986 9867 all phecode
426.23 Second degree AV block Circulatory System 0.924 0.837 – 1.02 0.118 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 0.998 0.917 – 1.09 0.967 587 5868 all phecode
426.25 Other heart block Circulatory System 0.992 0.827 – 1.19 0.933 131 1318 all phecode
426.3 Bundle branch block Circulatory System 1 0.967 – 1.04 0.918 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 1.01 0.954 – 1.06 0.818 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 1.02 0.972 – 1.07 0.401 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.919 0.802 – 1.05 0.226 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.01 0.776 – 1.32 0.94 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.998 0.957 – 1.04 0.924 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.995 0.953 – 1.04 0.836 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 0.986 0.973 – 1 0.0427 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 0.974 0.939 – 1.01 0.155 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.967 0.927 – 1.01 0.129 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.991 0.926 – 1.06 0.789 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 0.989 0.972 – 1.01 0.213 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.97 0.935 – 1.01 0.0976 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.01 0.956 – 1.08 0.628 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.05 0.942 – 1.18 0.37 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 1.04 0.97 – 1.1 0.296 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.983 0.92 – 1.05 0.615 952 9541 all phecode
427.6 Premature beats Circulatory System 0.961 0.878 – 1.05 0.383 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 0.956 0.793 – 1.15 0.638 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 1 0.958 – 1.05 0.955 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.03 0.929 – 1.14 0.583 402 4029 all phecode
427.9 Palpitations Circulatory System 0.997 0.964 – 1.03 0.865 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.996 0.969 – 1.02 0.766 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 0.971 0.928 – 1.02 0.202 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 0.996 0.965 – 1.03 0.778 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 0.999 0.926 – 1.08 0.986 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 1.08 0.842 – 1.39 0.532 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.979 0.895 – 1.07 0.634 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.02 0.887 – 1.18 0.76 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 0.984 0.938 – 1.03 0.495 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.966 0.9 – 1.04 0.34 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 0.998 0.928 – 1.07 0.964 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 1.03 0.909 – 1.16 0.661 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 0.986 0.964 – 1.01 0.207 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.01 0.948 – 1.07 0.853 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.01 0.88 – 1.15 0.912 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.979 0.949 – 1.01 0.188 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.962 0.915 – 1.01 0.126 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 0.963 0.927 – 1 0.0546 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 0.963 0.921 – 1.01 0.102 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 1.01 0.917 – 1.12 0.79 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.985 0.931 – 1.04 0.616 1279 12783 all phecode
440 Atherosclerosis Circulatory System 1.02 0.962 – 1.07 0.561 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.03 0.853 – 1.24 0.763 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.04 0.971 – 1.12 0.244 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 0.984 0.873 – 1.11 0.787 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 1 0.924 – 1.09 0.938 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.03 0.913 – 1.16 0.627 283 2827 all phecode
442 Other aneurysm Circulatory System 1.01 0.961 – 1.06 0.755 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 0.996 0.943 – 1.05 0.87 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.03 0.963 – 1.1 0.396 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 0.964 0.792 – 1.17 0.711 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.957 0.816 – 1.12 0.583 169 1696 all phecode
442.4 Arterial dissection Circulatory System 1.13 0.873 – 1.46 0.355 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.01 0.875 – 1.17 0.882 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 0.988 0.956 – 1.02 0.46 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 0.953 0.896 – 1.01 0.122 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.02 0.916 – 1.13 0.743 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 0.985 0.952 – 1.02 0.384 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1 0.962 – 1.04 0.925 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 0.987 0.921 – 1.06 0.701 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.01 0.923 – 1.1 0.859 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.01 0.944 – 1.09 0.693 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 0.96 0.827 – 1.11 0.587 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 1.01 0.911 – 1.12 0.856 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 1.12 0.981 – 1.28 0.0953 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 0.952 0.899 – 1.01 0.0933 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 0.957 0.892 – 1.03 0.227 868 8712 all phecode
448 Disease of capillaries Circulatory System 1.02 0.868 – 1.21 0.779 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.08 1 – 1.17 0.0423 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1 0.97 – 1.04 0.877 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1 0.968 – 1.04 0.947 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.954 0.875 – 1.04 0.293 564 5645 all phecode
454 Varicose veins Circulatory System 0.997 0.978 – 1.02 0.768 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1 0.983 – 1.02 0.821 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.967 0.891 – 1.05 0.419 624 6325 all phecode
455 Hemorrhoids Circulatory System 0.996 0.983 – 1.01 0.6 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.926 0.796 – 1.08 0.321 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.01 0.82 – 1.25 0.921 97 967 all phecode
458 Hypotension Circulatory System 0.979 0.952 – 1.01 0.123 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 1.01 0.95 – 1.06 0.839 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 0.962 0.84 – 1.1 0.579 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 0.97 0.937 – 1 0.0889 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 0.997 0.981 – 1.01 0.723 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 1.07 0.914 – 1.26 0.387 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 0.995 0.979 – 1.01 0.573 16103 159422 all phecode
464 Acute sinusitis Respiratory 1.02 0.879 – 1.18 0.818 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.04 0.992 – 1.08 0.112 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 1.04 0.965 – 1.11 0.334 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.995 0.848 – 1.17 0.952 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.02 0.986 – 1.05 0.286 4654 46553 all phecode
471 Nasal polyps Respiratory 1.09 1.06 – 1.13 8.02e-07 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.02 0.957 – 1.09 0.498 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1.02 0.979 – 1.06 0.347 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 1.03 0.842 – 1.25 0.805 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.01 0.894 – 1.14 0.858 264 2647 all phecode
473.4 Voice disturbance Respiratory 1.01 0.945 – 1.07 0.863 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 1.03 0.979 – 1.08 0.282 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 1.05 0.964 – 1.14 0.264 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.04 0.978 – 1.1 0.218 1122 11199 all phecode
475 Chronic sinusitis Respiratory 1.1 1.06 – 1.15 1.76e-06 2589 25882 all phecode
476 Allergic rhinitis Respiratory 0.987 0.926 – 1.05 0.676 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 0.989 0.949 – 1.03 0.607 2447 24452 all phecode
478 Throat pain Respiratory 1.01 0.907 – 1.12 0.889 377 3789 all phecode
479 Other upper respiratory disease Respiratory 1.01 0.975 – 1.04 0.69 4074 40737 all phecode
480 Pneumonia Respiratory 0.996 0.976 – 1.02 0.69 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 0.986 0.961 – 1.01 0.27 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 0.985 0.959 – 1.01 0.276 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 0.9 0.732 – 1.11 0.321 93 929 all phecode
480.2 Viral pneumonia Respiratory 1.15 0.909 – 1.45 0.247 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.03 0.834 – 1.26 0.806 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.04 0.964 – 1.11 0.339 794 7951 all phecode
481 Influenza Respiratory 1 0.895 – 1.12 0.96 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.915 0.787 – 1.06 0.245 193 1930 all phecode
495 Asthma Respiratory 1 0.989 – 1.02 0.738 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 1.02 0.898 – 1.16 0.762 250 2510 all phecode
496 Chronic airway obstruction Respiratory 0.999 0.979 – 1.02 0.95 10424 101546 all phecode
496.1 Emphysema Respiratory 0.98 0.933 – 1.03 0.41 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 0.991 0.954 – 1.03 0.636 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 0.997 0.958 – 1.04 0.865 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 1.03 0.979 – 1.08 0.287 1885 18859 all phecode
497 Bronchitis Respiratory 1 0.923 – 1.09 0.979 626 6267 all phecode
500 Lung disease due to external agents Respiratory 1.03 0.935 – 1.14 0.518 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.28 1.03 – 1.58 0.0234 79 784 all phecode
500.2 Pneumoconiosis Respiratory 0.957 0.838 – 1.09 0.518 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.02 0.938 – 1.1 0.689 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.03 0.962 – 1.1 0.404 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 0.935 0.854 – 1.02 0.151 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.02 0.913 – 1.15 0.686 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.03 0.796 – 1.33 0.825 61 610 all phecode
506 Empyema and pneumothorax Respiratory 1.05 0.987 – 1.11 0.123 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 1.01 0.984 – 1.04 0.483 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.05 1 – 1.1 0.0459 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.98 0.941 – 1.02 0.323 2599 26031 all phecode
509.1 Respiratory failure Respiratory 0.982 0.938 – 1.03 0.421 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 0.987 0.94 – 1.04 0.585 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 1.06 0.892 – 1.26 0.514 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.996 0.899 – 1.1 0.94 386 3863 all phecode
510 Other diseases of lung Respiratory 0.993 0.921 – 1.07 0.85 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 0.999 0.978 – 1.02 0.937 9031 90349 all phecode
512.1 Wheezing Respiratory 1.06 0.924 – 1.21 0.414 220 2196 all phecode
512.2 Painful respiration Respiratory 1.01 0.872 – 1.16 0.923 207 2075 all phecode
512.7 Shortness of breath Respiratory 1.01 0.98 – 1.03 0.637 5842 58498 all phecode
512.8 Cough Respiratory 0.982 0.945 – 1.02 0.352 2866 28642 all phecode
512.9 Other dyspnea Respiratory 1.01 0.944 – 1.08 0.763 914 9124 all phecode
513 Respiratory abnormalities Respiratory 1.03 0.948 – 1.12 0.495 611 6112 all phecode
513.3 Hypoventilation Respiratory 0.965 0.771 – 1.21 0.752 83 830 all phecode
513.4 Hyperventilation Respiratory 1.02 0.902 – 1.15 0.763 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 1.13 0.964 – 1.33 0.13 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 0.994 0.954 – 1.04 0.779 2465 24673 all phecode
516 Abnormal sputum Respiratory 1.02 0.979 – 1.07 0.313 2132 21335 all phecode
516.1 Hemoptysis Respiratory 1.01 0.967 – 1.06 0.605 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1 0.979 – 1.02 0.996 9366 93681 all phecode
519.2 Respiratory complications Respiratory 1.02 0.911 – 1.14 0.76 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1 0.981 – 1.02 0.841 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.04 0.928 – 1.17 0.483 303 3049 all phecode
520 Disorders of tooth development Digestive 0.995 0.952 – 1.04 0.841 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.04 0.787 – 1.37 0.786 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 0.99 0.949 – 1.03 0.629 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 0.996 0.96 – 1.03 0.849 3016 30245 all phecode
521.1 Dental caries Digestive 0.996 0.96 – 1.03 0.838 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.03 0.984 – 1.08 0.191 1774 17750 all phecode
522.5 Periapical abscess Digestive 1.02 0.965 – 1.09 0.427 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 1.02 0.973 – 1.08 0.367 1681 16812 all phecode
523.1 Gingivitis Digestive 1.01 0.835 – 1.23 0.903 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.02 0.956 – 1.08 0.614 1165 11650 all phecode
523.31 Acute periodontitis Digestive 1.01 0.934 – 1.1 0.77 666 6667 all phecode
523.32 Chronic periodontitis Digestive 1.02 0.936 – 1.11 0.644 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.2 1.07 – 1.34 0.00133 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.25 1.12 – 1.4 0.000118 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.996 0.957 – 1.04 0.833 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.27 0.999 – 1.61 0.0506 72 720 all phecode
526 Diseases of the jaws Digestive 0.999 0.934 – 1.07 0.975 928 9279 all phecode
526.1 Cysts of the jaws Digestive 0.884 0.787 – 0.992 0.0367 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.07 0.832 – 1.38 0.595 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.06 0.936 – 1.21 0.344 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.06 0.928 – 1.2 0.403 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 1.01 0.834 – 1.23 0.887 110 1098 all phecode
526.9 Jaw disease NOS Digestive 1.03 0.905 – 1.18 0.63 233 2329 all phecode
527 Diseases of the salivary glands Digestive 1.04 0.962 – 1.12 0.323 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 0.893 0.715 – 1.11 0.317 84 838 all phecode
527.2 Sialoadenitis Digestive 1.06 0.952 – 1.17 0.297 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 0.968 0.749 – 1.25 0.804 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.01 0.838 – 1.22 0.911 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.01 0.978 – 1.04 0.511 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 1.06 0.966 – 1.16 0.216 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.01 0.908 – 1.11 0.903 389 3884 all phecode
528.12 Oral aphthae Digestive 1.35 1.09 – 1.67 0.00665 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.03 0.882 – 1.19 0.741 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 1.08 0.898 – 1.29 0.431 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 1.15 0.94 – 1.41 0.174 94 940 all phecode
528.5 Diseases of lips Digestive 0.96 0.888 – 1.04 0.306 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 0.954 0.848 – 1.07 0.431 308 3079 all phecode
528.7 Sialolithiasis Digestive 1.02 0.906 – 1.14 0.791 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 1.02 0.958 – 1.08 0.59 1232 12312 all phecode
529.1 Glossitis Digestive 1.09 0.967 – 1.22 0.16 299 2986 all phecode
530 Diseases of esophagus Digestive 1.01 0.994 – 1.02 0.37 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.01 0.996 – 1.02 0.198 31253 272429 all phecode
530.11 GERD Digestive 1 0.99 – 1.02 0.563 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 1.03 0.998 – 1.06 0.072 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 1 0.984 – 1.02 0.718 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.974 0.925 – 1.02 0.3 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1 0.953 – 1.05 0.99 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 0.897 0.825 – 0.975 0.0108 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.912 0.775 – 1.07 0.272 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.93 0.832 – 1.04 0.204 341 3416 all phecode
530.9 Heartburn Digestive 1.01 0.969 – 1.06 0.563 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.984 0.96 – 1.01 0.197 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.969 0.894 – 1.05 0.447 637 6374 all phecode
531.2 Gastric ulcer Digestive 0.966 0.936 – 0.998 0.0382 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 0.995 0.958 – 1.03 0.776 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.14 1.03 – 1.26 0.00879 427 4268 all phecode
532 Dysphagia Digestive 1.01 0.98 – 1.03 0.689 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 0.986 0.974 – 0.999 0.0282 28078 261548 all phecode
535.1 Acute gastritis Digestive 0.978 0.921 – 1.04 0.475 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 1.01 0.909 – 1.13 0.836 370 3687 all phecode
535.6 Duodenitis Digestive 0.99 0.967 – 1.01 0.386 7592 75928 all phecode
535.8 Other specified gastritis Digestive 0.985 0.963 – 1.01 0.206 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.03 0.859 – 1.23 0.759 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.02 0.895 – 1.16 0.788 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 0.984 0.95 – 1.02 0.38 3391 33907 all phecode
540 Appendiceal conditions Digestive 0.985 0.949 – 1.02 0.431 3088 30890 all phecode
540.1 Appendicitis Digestive 0.983 0.946 – 1.02 0.394 2895 28963 all phecode
540.11 Acute appendicitis Digestive 0.975 0.936 – 1.02 0.224 2601 26019 all phecode
550 Abdominal hernia Digestive 0.994 0.984 – 1 0.229 45429 282640 all phecode
550.1 Inguinal hernia Digestive 0.997 0.981 – 1.01 0.73 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 0.992 0.979 – 1 0.214 26494 238953 all phecode
550.3 Femoral hernia Digestive 0.965 0.889 – 1.05 0.391 651 6504 all phecode
550.4 Umbilical hernia Digestive 0.988 0.955 – 1.02 0.48 3705 37072 all phecode
550.5 Ventral hernia Digestive 1.01 0.977 – 1.05 0.497 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 0.986 0.956 – 1.02 0.364 4444 44442 all phecode
555.1 Regional enteritis Digestive 0.952 0.905 – 1 0.0515 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 1 0.965 – 1.04 0.988 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 0.928 0.85 – 1.01 0.0953 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 1.02 0.959 – 1.09 0.503 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 1.01 0.93 – 1.09 0.872 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.91 0.807 – 1.03 0.125 299 2987 all phecode
557.1 Celiac disease Digestive 0.749 0.711 – 0.788 7.31e-29 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 0.985 0.969 – 1 0.0775 15492 155105 all phecode
559 Ileostomy status Digestive 1.03 0.98 – 1.08 0.246 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 0.965 0.934 – 0.998 0.0356 3936 39337 all phecode
560.1 Paralytic ileus Digestive 1.02 0.932 – 1.12 0.666 523 5231 all phecode
560.2 Impaction of intestine Digestive 1.01 0.895 – 1.15 0.817 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.95 0.884 – 1.02 0.161 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 0.965 0.931 – 1 0.0496 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 0.995 0.979 – 1.01 0.553 15772 157686 all phecode
561.1 Diarrhea Digestive 0.959 0.871 – 1.05 0.387 466 4653 all phecode
561.2 Flatulence Digestive 0.991 0.943 – 1.04 0.719 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 0.987 0.975 – 1 0.0529 26714 211692 all phecode
562.1 Diverticulosis Digestive 0.988 0.975 – 1 0.0564 26672 211642 all phecode
563 Constipation Digestive 1 0.981 – 1.02 0.89 10314 103140 all phecode
564 Functional digestive disorders Digestive 0.996 0.982 – 1.01 0.594 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 0.998 0.97 – 1.03 0.865 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1 0.954 – 1.05 0.916 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 0.995 0.979 – 1.01 0.552 15186 151648 all phecode
565 Anal and rectal conditions Digestive 1.01 0.994 – 1.03 0.204 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 1.01 0.982 – 1.03 0.615 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 0.991 0.926 – 1.06 0.802 929 9293 all phecode
568 Other disorders of peritoneum Digestive 1 0.965 – 1.04 0.998 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.01 0.976 – 1.05 0.511 3101 30987 all phecode
569 Other disorders of intestine Digestive 0.983 0.952 – 1.01 0.295 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.05 0.89 – 1.24 0.547 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 1.02 0.925 – 1.12 0.749 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.03 0.991 – 1.07 0.134 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.02 0.97 – 1.07 0.437 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.823 0.676 – 1 0.0529 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 1.05 0.923 – 1.19 0.459 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.06 0.991 – 1.13 0.0914 976 9804 all phecode
571.81 Portal hypertension Digestive 1 0.919 – 1.1 0.928 528 5285 all phecode
572 Ascites (non malignant) Digestive 0.974 0.923 – 1.03 0.328 1544 15454 all phecode
573 Other disorders of liver Digestive 1.02 0.965 – 1.07 0.504 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 1.05 0.857 – 1.28 0.643 96 960 all phecode
573.3 Hepatomegaly Digestive 1.01 0.892 – 1.13 0.918 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 0.978 0.913 – 1.05 0.524 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 0.988 0.954 – 1.02 0.514 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 0.883 0.764 – 1.02 0.0925 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 0.993 0.977 – 1.01 0.387 15607 156123 all phecode
574.1 Cholelithiasis Digestive 0.989 0.972 – 1.01 0.233 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.969 0.919 – 1.02 0.252 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.978 0.951 – 1.01 0.117 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 0.981 0.943 – 1.02 0.361 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1 0.963 – 1.04 0.954 2748 27523 all phecode
575 Other biliary tract disease Digestive 0.965 0.934 – 0.998 0.0369 3867 38724 all phecode
575.1 Cholangitis Digestive 0.87 0.791 – 0.958 0.00434 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 1.01 0.938 – 1.09 0.792 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.963 0.875 – 1.06 0.437 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 0.979 0.927 – 1.03 0.448 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 0.955 0.896 – 1.02 0.16 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1 0.893 – 1.12 0.994 348 3488 all phecode
577 Diseases of pancreas Digestive 1 0.961 – 1.04 0.984 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 1.01 0.961 – 1.05 0.791 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 0.954 0.87 – 1.04 0.308 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.05 0.941 – 1.17 0.396 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.991 – 1.02 0.491 20626 206278 all phecode
578.1 Hematemesis Digestive 1.02 0.973 – 1.07 0.416 1958 19564 all phecode
578.2 Blood in stool Digestive 0.997 0.958 – 1.04 0.895 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1 0.987 – 1.02 0.624 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.02 0.99 – 1.05 0.212 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.05 0.996 – 1.11 0.0706 1548 15498 all phecode
579.2 Splenomegaly Digestive 1.07 0.965 – 1.18 0.209 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.995 0.946 – 1.05 0.841 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.997 0.946 – 1.05 0.913 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 1.01 0.948 – 1.08 0.74 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.997 0.78 – 1.27 0.981 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.871 0.725 – 1.05 0.14 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.03 0.957 – 1.1 0.468 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.945 0.857 – 1.04 0.248 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.953 0.835 – 1.09 0.478 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.947 0.83 – 1.08 0.419 253 2529 all phecode
585 Renal failure Genitourinary 0.961 0.937 – 0.985 0.00156 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 0.95 0.921 – 0.979 0.001 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 0.948 0.898 – 1 0.0552 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.948 0.911 – 0.988 0.0102 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 1.03 0.935 – 1.12 0.597 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 0.984 0.95 – 1.02 0.389 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.927 0.804 – 1.07 0.299 208 2089 all phecode
586.11 Small kidney Genitourinary 0.972 0.834 – 1.13 0.718 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 0.996 0.94 – 1.06 0.9 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.813 0.645 – 1.03 0.0801 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.02 0.95 – 1.09 0.628 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 1.04 0.933 – 1.15 0.508 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 0.974 0.795 – 1.19 0.804 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 0.995 0.818 – 1.21 0.962 116 1158 all phecode
590 Pyelonephritis Genitourinary 1.02 0.961 – 1.08 0.559 1328 13285 all phecode
591 Urinary tract infection Genitourinary 0.985 0.967 – 1 0.117 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 1.01 0.969 – 1.05 0.743 2966 29661 all phecode
592.1 Cystitis Genitourinary 1.01 0.973 – 1.05 0.565 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 1.08 0.905 – 1.29 0.397 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 1.02 0.948 – 1.09 0.651 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 1.05 0.923 – 1.19 0.463 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.07 0.911 – 1.26 0.412 165 1662 all phecode
593 Hematuria Genitourinary 1.01 0.996 – 1.03 0.154 16068 160204 all phecode
594 Urinary calculus Genitourinary 1 0.979 – 1.03 0.741 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 1.02 0.986 – 1.06 0.231 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 0.976 0.906 – 1.05 0.521 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 0.989 0.949 – 1.03 0.608 2401 24024 all phecode
594.8 Renal colic Genitourinary 0.983 0.94 – 1.03 0.459 2050 20500 all phecode
595 Hydronephrosis Genitourinary 0.952 0.908 – 0.998 0.0396 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 0.995 0.974 – 1.02 0.615 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 1.01 0.96 – 1.05 0.817 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 0.976 0.928 – 1.03 0.353 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.977 0.945 – 1.01 0.165 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.98 0.945 – 1.02 0.259 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 0.963 0.763 – 1.21 0.748 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 0.975 0.941 – 1.01 0.15 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.988 0.878 – 1.11 0.847 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.992 – 1.02 0.38 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 0.934 0.799 – 1.09 0.391 166 1670 all phecode
599.2 Retention of urine Genitourinary 0.999 0.974 – 1.02 0.948 6718 67168 all phecode
599.3 Dysuria Genitourinary 1.02 0.96 – 1.08 0.539 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 1.01 0.987 – 1.03 0.425 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.01 0.977 – 1.04 0.561 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 1.01 0.823 – 1.24 0.925 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 0.875 0.679 – 1.13 0.3 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 1 0.957 – 1.05 0.897 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 1 0.983 – 1.02 0.78 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 1.02 0.971 – 1.06 0.503 2081 20818 all phecode
601.1 Prostatitis Genitourinary 1.02 0.971 – 1.08 0.405 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 1.02 0.898 – 1.17 0.724 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 1.06 0.987 – 1.13 0.114 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 0.911 0.695 – 1.19 0.5 59 588 all phecode
601.4 Balanoposthitis Genitourinary 0.981 0.868 – 1.11 0.758 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.07 0.953 – 1.2 0.25 303 3019 all phecode
602 Other disorders of prostate Genitourinary 1.01 0.96 – 1.07 0.606 1341 13408 all phecode
603 Other disorders of testis Genitourinary 0.966 0.924 – 1.01 0.129 2150 21512 all phecode
603.1 Hydrocele Genitourinary 0.956 0.903 – 1.01 0.124 1339 13402 all phecode
604 Disorders of penis Genitourinary 1.02 0.987 – 1.06 0.213 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.03 0.986 – 1.07 0.212 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.03 0.912 – 1.16 0.631 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 1 0.966 – 1.04 0.827 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.05 0.91 – 1.2 0.52 214 2138 all phecode
609.1 Infertility, male Genitourinary 0.907 0.691 – 1.19 0.48 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 1.1 0.939 – 1.29 0.236 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 1.01 0.964 – 1.05 0.811 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 0.999 0.934 – 1.07 0.968 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 0.973 0.864 – 1.1 0.656 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 1.12 0.997 – 1.26 0.0568 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.999 0.945 – 1.06 0.966 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.01 0.932 – 1.09 0.856 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.982 0.932 – 1.03 0.482 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 1.15 0.885 – 1.5 0.292 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 0.984 0.934 – 1.04 0.558 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.05 0.976 – 1.12 0.209 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.04 0.97 – 1.12 0.26 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 1.09 0.865 – 1.38 0.457 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 0.963 0.915 – 1.01 0.142 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 0.925 0.856 – 0.999 0.0483 720 7210 all phecode
613.5 Mastodynia Genitourinary 1.08 0.874 – 1.35 0.46 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.949 0.877 – 1.03 0.189 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 1.02 0.907 – 1.14 0.769 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 1.1 0.955 – 1.27 0.184 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.01 0.979 – 1.03 0.644 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.998 0.958 – 1.04 0.938 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.04 0.964 – 1.11 0.339 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.12 0.871 – 1.43 0.383 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.01 0.913 – 1.11 0.87 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.11 0.996 – 1.23 0.0593 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.04 0.921 – 1.18 0.515 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.998 0.958 – 1.04 0.908 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.02 0.962 – 1.08 0.536 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.04 0.944 – 1.15 0.411 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.968 0.898 – 1.04 0.4 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.976 0.86 – 1.11 0.703 274 2737 all phecode
615 Endometriosis Genitourinary 0.975 0.944 – 1.01 0.121 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.02 0.905 – 1.14 0.769 304 3037 all phecode
618 Genital prolapse Genitourinary 0.996 0.977 – 1.02 0.681 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 0.989 0.966 – 1.01 0.377 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.01 0.981 – 1.04 0.548 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.03 0.945 – 1.13 0.478 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.989 0.914 – 1.07 0.782 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 1.01 0.993 – 1.04 0.195 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.998 0.925 – 1.08 0.958 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1.03 0.996 – 1.07 0.086 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1 0.963 – 1.04 0.969 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.999 0.952 – 1.05 0.984 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.987 0.933 – 1.04 0.647 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 0.858 0.663 – 1.11 0.244 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 1.05 0.988 – 1.11 0.117 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 0.996 0.977 – 1.02 0.725 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.991 0.968 – 1.01 0.426 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 1.01 0.979 – 1.05 0.446 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 0.955 0.902 – 1.01 0.119 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 0.984 0.915 – 1.06 0.671 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.961 0.841 – 1.1 0.565 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.974 0.884 – 1.07 0.598 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 1.03 1 – 1.06 0.0315 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.01 0.974 – 1.05 0.539 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 0.989 0.932 – 1.05 0.719 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.986 0.97 – 1 0.102 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.98 0.963 – 0.997 0.0224 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.902 0.745 – 1.09 0.293 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 0.99 0.97 – 1.01 0.367 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 1.03 0.982 – 1.08 0.236 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.96 0.928 – 0.992 0.0154 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 0.964 0.918 – 1.01 0.143 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.984 0.837 – 1.16 0.845 159 1587 all phecode
626.8 Infertility, female Genitourinary 1.01 0.959 – 1.07 0.629 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1 0.981 – 1.02 0.892 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 1.01 0.984 – 1.03 0.632 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 1.16 0.996 – 1.35 0.0571 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.969 0.91 – 1.03 0.318 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 1.1 0.978 – 1.23 0.113 310 3097 all phecode
628 Ovarian cyst Genitourinary 1 0.972 – 1.03 0.914 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.995 0.967 – 1.02 0.757 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.02 0.958 – 1.08 0.564 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.02 0.911 – 1.15 0.713 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.982 0.938 – 1.03 0.453 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.975 0.909 – 1.05 0.48 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.994 0.939 – 1.05 0.849 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.01 0.965 – 1.05 0.724 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.982 0.904 – 1.07 0.668 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.02 0.959 – 1.09 0.514 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 0.987 0.778 – 1.25 0.915 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.01 0.949 – 1.07 0.766 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.04 0.926 – 1.17 0.5 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.05 0.913 – 1.21 0.495 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.972 0.825 – 1.15 0.735 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.98 0.924 – 1.04 0.487 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1 0.959 – 1.05 0.924 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.01 0.788 – 1.28 0.964 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.921 0.814 – 1.04 0.196 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.883 0.731 – 1.07 0.197 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.02 0.883 – 1.18 0.763 193 1922 all phecode
650 Normal delivery Pregnancy Complications 1.03 0.985 – 1.08 0.188 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 0.989 0.886 – 1.1 0.849 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.988 0.94 – 1.04 0.634 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.979 0.927 – 1.03 0.458 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.12 0.894 – 1.41 0.322 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.986 0.955 – 1.02 0.398 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.999 0.825 – 1.21 0.993 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.982 0.94 – 1.03 0.43 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.964 0.882 – 1.05 0.425 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.985 0.956 – 1.01 0.315 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.998 0.958 – 1.04 0.929 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.933 0.796 – 1.09 0.397 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.1 0.969 – 1.24 0.146 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.965 0.746 – 1.25 0.789 63 624 all phecode
679 Complications of in utero procedures Dermatologic 1.07 0.803 – 1.42 0.652 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 0.987 0.963 – 1.01 0.274 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.11 1.02 – 1.21 0.0165 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.08 0.987 – 1.18 0.0935 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.974 0.948 – 1 0.0687 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.976 0.949 – 1 0.0844 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.974 0.947 – 1 0.0623 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 0.97 0.891 – 1.06 0.487 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 0.988 0.934 – 1.04 0.668 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 0.984 0.942 – 1.03 0.451 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 1.01 0.928 – 1.1 0.816 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 0.942 0.844 – 1.05 0.29 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1.05 0.968 – 1.15 0.223 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.985 0.942 – 1.03 0.515 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.05 0.929 – 1.18 0.46 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 0.904 0.746 – 1.1 0.307 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 0.983 0.946 – 1.02 0.39 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.01 0.981 – 1.04 0.584 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.746 0.581 – 0.958 0.0218 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.703 0.523 – 0.945 0.0196 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 0.934 0.775 – 1.12 0.469 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.999 0.936 – 1.07 0.971 986 9854 all phecode
694.1 Vitiligo Dermatologic 1.02 0.786 – 1.32 0.902 60 599 all phecode
694.2 Other dyschromia Dermatologic 0.998 0.928 – 1.07 0.964 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 0.972 0.805 – 1.17 0.763 117 1170 all phecode
695 Erythematous conditions Dermatologic 1 0.961 – 1.04 0.927 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 0.996 0.821 – 1.21 0.965 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 0.947 0.795 – 1.13 0.538 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 0.732 0.55 – 0.975 0.033 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.16 0.916 – 1.48 0.215 73 727 all phecode
695.3 Rosacea Dermatologic 0.968 0.862 – 1.09 0.591 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 0.939 0.848 – 1.04 0.232 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.874 0.728 – 1.05 0.152 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 0.963 0.861 – 1.08 0.505 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 1.07 0.993 – 1.15 0.0763 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 1 0.883 – 1.14 0.957 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 1.13 0.911 – 1.41 0.261 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 0.956 0.87 – 1.05 0.357 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 1.04 1 – 1.09 0.0451 2252 22509 all phecode
696.4 Psoriasis Dermatologic 1.04 0.998 – 1.09 0.0642 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.04 0.985 – 1.09 0.168 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.06 0.984 – 1.15 0.123 706 7052 all phecode
697 Sarcoidosis Dermatologic 0.832 0.759 – 0.913 9.04e-05 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 1.03 0.96 – 1.11 0.385 782 7814 all phecode
700 Corns and callosities Dermatologic 0.889 0.789 – 1 0.0554 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.01 0.978 – 1.04 0.59 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 0.906 0.719 – 1.14 0.401 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1 0.962 – 1.05 0.871 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.14 0.898 – 1.45 0.279 61 610 all phecode
701.4 Keloid scar Dermatologic 0.98 0.853 – 1.13 0.773 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 0.969 0.879 – 1.07 0.529 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.05 0.86 – 1.27 0.648 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.03 1.01 – 1.06 0.0157 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 1.04 1 – 1.09 0.0326 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 1.03 0.997 – 1.07 0.0724 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 1.01 0.908 – 1.12 0.858 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 0.965 0.902 – 1.03 0.294 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 0.97 0.943 – 0.998 0.0349 5267 52727 all phecode
704.1 Alopecia Dermatologic 1.08 0.903 – 1.29 0.398 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.21 0.971 – 1.51 0.0889 76 759 all phecode
705 Disorders of sweat glands Dermatologic 1.01 0.88 – 1.15 0.938 228 2287 all phecode
705.3 Hidradenitis Dermatologic 0.907 0.781 – 1.05 0.205 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 1.01 0.929 – 1.1 0.81 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 0.972 0.95 – 0.994 0.0127 8317 83195 all phecode
706.1 Acne Dermatologic 1.17 0.942 – 1.45 0.157 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 0.977 0.955 – 0.998 0.035 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 0.989 0.944 – 1.04 0.637 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 0.968 0.905 – 1.04 0.352 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.992 0.958 – 1.03 0.657 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 1.01 0.927 – 1.11 0.756 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 1.09 0.933 – 1.28 0.277 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.77 0.592 – 1 0.0529 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.992 0.953 – 1.03 0.676 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.944 0.867 – 1.03 0.182 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 0.959 0.878 – 1.05 0.352 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.928 0.8 – 1.08 0.321 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.924 0.831 – 1.03 0.141 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 0.981 0.887 – 1.08 0.708 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 0.956 0.853 – 1.07 0.441 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 0.91 0.733 – 1.13 0.395 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.927 0.782 – 1.1 0.383 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 0.938 0.732 – 1.2 0.615 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.13 1.1 – 1.17 2.55e-17 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.15 1.11 – 1.18 2.69e-18 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.08 1.03 – 1.14 0.00191 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.24 1.03 – 1.5 0.0238 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.23 1.13 – 1.33 6.79e-07 618 6177 all phecode
716 Other arthropathies Musculoskeletal 1.01 1 – 1.02 0.054 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.01 0.971 – 1.04 0.774 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 1 0.988 – 1.02 0.566 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.01 1 – 1.02 0.0328 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.05 0.988 – 1.11 0.119 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 1 0.969 – 1.04 0.9 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 0.997 0.974 – 1.02 0.804 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.99 0.962 – 1.02 0.488 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.903 0.779 – 1.05 0.179 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.05 0.947 – 1.17 0.336 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 0.986 0.965 – 1.01 0.195 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.982 0.898 – 1.07 0.694 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.998 0.961 – 1.04 0.927 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.11 0.869 – 1.41 0.412 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.972 0.942 – 1 0.0753 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 0.99 0.905 – 1.08 0.828 517 5173 all phecode
723.1 Torticollis Musculoskeletal 0.961 0.786 – 1.17 0.699 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 0.997 0.953 – 1.04 0.886 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.04 0.937 – 1.15 0.481 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 1.03 0.934 – 1.14 0.531 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.17 0.918 – 1.48 0.208 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 0.981 0.932 – 1.03 0.451 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1 0.983 – 1.02 0.991 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 0.999 0.979 – 1.02 0.963 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 1.07 0.954 – 1.2 0.251 334 3336 all phecode
726.3 Bursitis Musculoskeletal 1 0.935 – 1.08 0.937 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1 0.977 – 1.03 0.95 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.03 0.995 – 1.08 0.0863 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 0.93 0.756 – 1.14 0.496 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1 0.966 – 1.04 0.916 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 0.949 0.871 – 1.03 0.23 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.97 0.871 – 1.08 0.582 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.952 0.799 – 1.13 0.585 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.02 0.982 – 1.05 0.35 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.1 0.996 – 1.22 0.0602 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 1.02 0.985 – 1.05 0.292 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.02 0.982 – 1.05 0.345 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 0.999 0.973 – 1.03 0.929 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.02 0.953 – 1.08 0.615 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 0.994 0.814 – 1.21 0.955 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.06 0.941 – 1.2 0.331 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.05 0.923 – 1.19 0.474 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 0.963 0.875 – 1.06 0.437 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.94 0.814 – 1.08 0.394 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.983 0.752 – 1.28 0.897 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.997 0.95 – 1.05 0.91 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 1.04 0.923 – 1.17 0.536 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.944 0.864 – 1.03 0.2 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 1.04 0.875 – 1.25 0.635 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.966 0.912 – 1.02 0.241 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 0.966 0.801 – 1.17 0.719 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 1.03 1.01 – 1.06 0.00171 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 1.01 0.871 – 1.17 0.883 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 1.03 1 – 1.06 0.0386 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.03 0.984 – 1.08 0.202 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 0.981 0.931 – 1.03 0.46 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.04 1.01 – 1.06 0.00327 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.972 0.924 – 1.02 0.268 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 0.942 0.827 – 1.07 0.363 248 2476 all phecode
737 Curvature of spine Musculoskeletal 0.993 0.935 – 1.06 0.828 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.987 0.927 – 1.05 0.685 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.997 0.952 – 1.04 0.899 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.01 0.956 – 1.06 0.776 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 0.973 0.887 – 1.07 0.569 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 1.01 0.997 – 1.02 0.123 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1 0.989 – 1.02 0.573 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1 0.98 – 1.02 0.877 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.987 0.884 – 1.1 0.811 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.02 0.936 – 1.11 0.684 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.01 0.996 – 1.03 0.129 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.02 0.99 – 1.06 0.171 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 1.04 0.855 – 1.28 0.668 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 0.956 0.879 – 1.04 0.289 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 0.893 0.754 – 1.06 0.193 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 1.01 0.959 – 1.07 0.665 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 1.14 0.942 – 1.37 0.18 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 0.923 0.703 – 1.21 0.561 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.02 0.979 – 1.06 0.377 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 1.05 0.939 – 1.17 0.401 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.05 0.858 – 1.28 0.641 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.05 0.958 – 1.15 0.298 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 1 0.955 – 1.05 0.994 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1 0.979 – 1.03 0.836 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 1 0.979 – 1.03 0.767 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 1.01 0.978 – 1.03 0.712 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1.01 0.928 – 1.1 0.782 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 0.954 0.871 – 1.04 0.307 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.01 0.941 – 1.09 0.763 815 8144 all phecode
745 Pain in joint Musculoskeletal 1 0.981 – 1.03 0.773 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.984 0.947 – 1.02 0.428 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.985 0.947 – 1.03 0.47 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.93 0.854 – 1.01 0.0987 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.01 0.885 – 1.15 0.876 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.989 0.943 – 1.04 0.657 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.95 0.807 – 1.12 0.539 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.23 0.925 – 1.64 0.152 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.943 0.837 – 1.06 0.333 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 1 0.925 – 1.08 0.969 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.978 0.872 – 1.1 0.709 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.953 0.82 – 1.11 0.53 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.01 0.902 – 1.12 0.922 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.03 0.903 – 1.18 0.629 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.957 0.792 – 1.16 0.647 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.01 0.961 – 1.07 0.646 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.02 0.947 – 1.1 0.571 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.982 0.893 – 1.08 0.702 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.04 0.904 – 1.19 0.597 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1 0.935 – 1.08 0.921 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 1.04 0.947 – 1.15 0.388 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.949 0.847 – 1.06 0.36 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.953 0.852 – 1.07 0.404 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 0.96 0.844 – 1.09 0.53 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 0.93 0.808 – 1.07 0.31 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.06 0.852 – 1.33 0.58 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.09 0.912 – 1.3 0.342 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.32 1.06 – 1.64 0.0125 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.18 0.975 – 1.42 0.0888 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.971 0.878 – 1.07 0.557 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.966 0.84 – 1.11 0.628 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.05 0.891 – 1.23 0.582 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.01 0.824 – 1.23 0.959 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.928 0.853 – 1.01 0.0875 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.952 0.762 – 1.19 0.663 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.932 0.845 – 1.03 0.158 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.08 0.917 – 1.27 0.361 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.2 0.931 – 1.54 0.162 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.09 0.952 – 1.25 0.212 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.978 0.787 – 1.22 0.843 96 959 all phecode
760 Back pain Symptoms 0.99 0.971 – 1.01 0.294 11126 111353 all phecode
761 Cervicalgia Symptoms 1 0.956 – 1.05 0.908 1791 17901 all phecode
764 Sciatica Symptoms 0.958 0.918 – 0.999 0.0473 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.01 0.952 – 1.07 0.732 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 0.991 0.912 – 1.08 0.833 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.02 0.955 – 1.1 0.499 870 8687 all phecode
771.1 Swelling of limb Symptoms 1 0.97 – 1.03 0.982 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 0.973 0.898 – 1.05 0.496 659 6581 all phecode
773 Pain in limb Symptoms 0.992 0.967 – 1.02 0.552 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 0.829 0.704 – 0.975 0.0237 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1 0.955 – 1.05 0.958 1870 18715 all phecode
782.3 Edema Symptoms 0.98 0.932 – 1.03 0.446 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 1.03 0.882 – 1.19 0.747 175 1748 all phecode
783 Fever of unknown origin Symptoms 1.02 0.987 – 1.05 0.228 3911 39105 all phecode
785 Abdominal pain Symptoms 1 0.989 – 1.01 0.972 40080 301686 all phecode
788 Syncope and collapse Symptoms 0.995 0.974 – 1.02 0.643 9069 90813 all phecode
789 Nausea and vomiting Symptoms 1.01 0.986 – 1.02 0.595 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.02 0.865 – 1.21 0.8 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 0.921 0.736 – 1.15 0.475 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 0.996 0.971 – 1.02 0.758 6357 63635 all phecode
791 Gangrene Symptoms 0.998 0.914 – 1.09 0.971 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1.08 0.883 – 1.31 0.467 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.94 0.788 – 1.12 0.487 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 0.996 0.914 – 1.08 0.921 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.01 0.838 – 1.22 0.921 120 1198 all phecode
797 Shock Symptoms 1.03 0.879 – 1.21 0.69 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 1.08 0.883 – 1.31 0.466 102 1020 all phecode
798 Malaise and fatigue Symptoms 0.985 0.951 – 1.02 0.415 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 0.927 0.851 – 1.01 0.0818 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 0.983 0.959 – 1.01 0.183 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.01 0.966 – 1.06 0.572 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.936 0.8 – 1.1 0.414 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.985 0.943 – 1.03 0.512 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 1.05 0.972 – 1.13 0.228 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.993 0.951 – 1.04 0.752 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 1 0.957 – 1.05 0.886 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 1.08 1 – 1.17 0.0398 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 1.02 0.996 – 1.04 0.114 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 0.979 0.931 – 1.03 0.397 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.03 1 – 1.06 0.0418 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.03 0.974 – 1.08 0.332 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.985 0.951 – 1.02 0.419 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.952 0.9 – 1.01 0.0863 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 0.957 0.889 – 1.03 0.243 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.999 0.944 – 1.06 0.962 1300 12998 all phecode
817 Concussion Injuries & Poisonings 1.08 0.952 – 1.23 0.225 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.957 0.874 – 1.05 0.343 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.983 0.946 – 1.02 0.359 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 0.97 0.923 – 1.02 0.242 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 0.984 0.941 – 1.03 0.498 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 0.994 0.977 – 1.01 0.457 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 0.988 0.904 – 1.08 0.791 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 0.938 0.85 – 1.03 0.195 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.999 0.971 – 1.03 0.92 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.08 0.913 – 1.27 0.383 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.02 0.931 – 1.12 0.66 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.961 0.915 – 1.01 0.102 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.948 0.894 – 1.01 0.0736 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.03 0.995 – 1.07 0.0894 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1 0.967 – 1.04 0.923 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1.08 0.844 – 1.38 0.536 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.988 0.954 – 1.02 0.489 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.02 0.898 – 1.15 0.809 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.889 0.767 – 1.03 0.114 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.998 0.96 – 1.04 0.907 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.944 0.82 – 1.09 0.422 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 0.969 0.755 – 1.24 0.802 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 0.98 0.949 – 1.01 0.229 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.16 0.898 – 1.49 0.259 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.25 1.02 – 1.52 0.03 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.962 0.828 – 1.12 0.612 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 0.937 0.852 – 1.03 0.177 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 1.01 0.876 – 1.15 0.936 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.07 0.923 – 1.25 0.355 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 0.975 0.829 – 1.15 0.761 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 0.967 0.914 – 1.02 0.249 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 0.999 0.968 – 1.03 0.966 4260 42663 all phecode
916 Contusion Injuries & Poisonings 0.974 0.923 – 1.03 0.329 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 1.09 0.941 – 1.27 0.242 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.05 0.946 – 1.16 0.37 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 1.03 0.903 – 1.17 0.687 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.959 0.917 – 1 0.0713 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.94 0.819 – 1.08 0.384 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.04 0.857 – 1.27 0.666 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.01 0.928 – 1.1 0.799 550 5509 all phecode
947 Urticaria Injuries & Poisonings 1 0.904 – 1.12 0.934 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 0.991 0.894 – 1.1 0.866 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.989 0.896 – 1.09 0.821 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.02 0.899 – 1.16 0.751 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.05 0.96 – 1.15 0.277 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.21 0.915 – 1.61 0.179 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.27 1.01 – 1.6 0.0381 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.983 0.968 – 0.998 0.0245 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.983 0.967 – 0.999 0.0371 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1 0.909 – 1.11 0.923 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.01 0.943 – 1.08 0.75 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.996 0.894 – 1.11 0.938 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.02 0.916 – 1.14 0.703 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.925 0.807 – 1.06 0.26 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.01 0.893 – 1.13 0.918 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.988 0.875 – 1.11 0.84 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.992 0.967 – 1.02 0.575 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.01 0.952 – 1.07 0.717 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.989 0.9 – 1.09 0.817 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.92 0.829 – 1.02 0.115 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.05 0.961 – 1.15 0.277 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.02 0.939 – 1.11 0.616 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.02 0.97 – 1.06 0.497 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.915 0.787 – 1.06 0.248 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.875 0.77 – 0.995 0.0415 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.724 0.575 – 0.913 0.0063 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 0.97 0.798 – 1.18 0.756 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.02 0.828 – 1.25 0.864 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.01 0.782 – 1.3 0.945 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.04 0.797 – 1.36 0.763 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.964 0.844 – 1.1 0.592 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.01 0.936 – 1.09 0.778 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.923 0.796 – 1.07 0.285 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.15 0.895 – 1.47 0.278 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.14 0.934 – 1.39 0.197 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 1.02 0.846 – 1.24 0.804 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.972 0.789 – 1.2 0.789 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 0.995 0.959 – 1.03 0.789 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 0.985 0.949 – 1.02 0.437 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 0.985 0.949 – 1.02 0.437 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 0.994 0.972 – 1.02 0.59 8590 87934 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.03 0.993 – 1.08 0.104 2636 27027 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.04 0.958 – 1.13 0.344 600 6492 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 0.972 0.905 – 1.04 0.429 842 8570 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.32 1.02 – 1.71 0.036 53 548 exclusion phecode
010 Tuberculosis Infectious Diseases 0.971 0.825 – 1.14 0.725 161 1657 exclusion phecode
038 Septicemia Infectious Diseases 0.953 0.922 – 0.986 0.0055 3710 41570 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 0.938 0.871 – 1.01 0.0889 767 8459 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 0.985 0.894 – 1.09 0.763 440 4940 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 0.978 0.96 – 0.997 0.0253 11654 119808 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 0.964 0.929 – 1 0.0572 3014 31207 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.05 0.994 – 1.1 0.0824 1579 16362 exclusion phecode
041.4 E. coli Infectious Diseases 0.971 0.933 – 1.01 0.151 2638 27189 exclusion phecode
053 Herpes zoster Infectious Diseases 1.05 0.94 – 1.17 0.397 353 4105 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.13 0.912 – 1.41 0.258 90 943 exclusion phecode
054 Herpes simplex Infectious Diseases 0.992 0.856 – 1.15 0.918 189 2096 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.03 0.947 – 1.12 0.504 582 5887 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.11 0.878 – 1.41 0.377 69 683 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 1.03 0.868 – 1.22 0.743 131 1321 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.05 0.923 – 1.19 0.463 250 2561 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 0.961 0.846 – 1.09 0.536 273 2753 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1 0.909 – 1.11 0.932 416 4265 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.18 1 – 1.39 0.0459 141 1460 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.24 1.03 – 1.49 0.0238 111 1162 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.969 0.907 – 1.03 0.339 992 9971 exclusion phecode
079 Viral infection Infectious Diseases 0.996 0.957 – 1.04 0.838 2668 27569 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.977 0.757 – 1.26 0.859 60 639 exclusion phecode
080 Postoperative infection Infectious Diseases 0.984 0.954 – 1.01 0.301 4402 44523 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 0.966 0.925 – 1.01 0.112 2320 24611 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.831 0.648 – 1.07 0.146 70 707 exclusion phecode
1000 Burns Injuries & Poisonings 1.04 0.957 – 1.14 0.341 572 5762 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 0.995 0.937 – 1.06 0.863 1189 11933 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.01 0.985 – 1.04 0.367 5349 54486 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 0.97 0.861 – 1.09 0.617 296 2980 exclusion phecode
1005 Other symptoms Injuries & Poisonings 1.01 0.956 – 1.07 0.725 1378 14335 exclusion phecode
1006 Crushing injury Injuries & Poisonings 1.14 1 – 1.29 0.0467 252 2539 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 0.977 0.86 – 1.11 0.718 254 2547 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.02 0.953 – 1.08 0.627 1008 10064 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 0.985 0.963 – 1.01 0.183 8420 84411 exclusion phecode
1010 Other tests Injuries & Poisonings 0.995 0.968 – 1.02 0.698 5779 59189 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1 0.978 – 1.02 0.983 8987 91000 exclusion phecode
1012 Late effect Injuries & Poisonings 1.2 0.988 – 1.45 0.0669 104 1050 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.1 0.985 – 1.24 0.0879 308 3150 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.919 0.716 – 1.18 0.508 66 654 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 0.995 0.964 – 1.03 0.778 4177 42058 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1 0.988 – 1.02 0.588 15682 158153 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.905 0.798 – 1.03 0.123 272 2794 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.921 0.811 – 1.05 0.209 266 2733 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.836 0.654 – 1.07 0.154 73 751 exclusion phecode
110.12 Althete's foot Infectious Diseases 0.875 0.732 – 1.05 0.142 138 1401 exclusion phecode
112 Candidiasis Infectious Diseases 0.96 0.917 – 1.01 0.0836 2029 21152 exclusion phecode
117 Mycoses Infectious Diseases 1.02 0.899 – 1.15 0.774 255 2695 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.01 0.865 – 1.19 0.869 158 1632 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.964 0.774 – 1.2 0.744 80 796 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 0.926 0.724 – 1.18 0.539 67 683 exclusion phecode
134 Helminthiases Infectious Diseases 0.829 0.683 – 1.01 0.0571 125 1259 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 0.822 0.668 – 1.01 0.0641 106 1054 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.02 0.885 – 1.18 0.748 193 2036 exclusion phecode
145 Cancer of mouth Neoplasms 1.02 0.937 – 1.1 0.714 628 6380 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.06 0.947 – 1.19 0.295 303 3078 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 1.02 0.836 – 1.24 0.861 103 1043 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.02 0.772 – 1.33 0.913 52 533 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.05 0.969 – 1.14 0.236 618 6292 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.11 0.972 – 1.26 0.125 246 2498 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.01 0.889 – 1.14 0.893 259 2613 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.01 0.774 – 1.32 0.936 56 567 exclusion phecode
150 Cancer of esophagus Neoplasms 0.984 0.913 – 1.06 0.675 752 7563 exclusion phecode
151 Cancer of stomach Neoplasms 1.04 0.956 – 1.14 0.347 560 5646 exclusion phecode
153 Colorectal cancer Neoplasms 0.989 0.959 – 1.02 0.475 4516 45513 exclusion phecode
153.2 Colon cancer Neoplasms 1 0.964 – 1.04 0.997 3055 30853 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.969 0.927 – 1.01 0.178 2135 21515 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.922 0.828 – 1.03 0.14 392 3980 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.926 0.781 – 1.1 0.374 154 1570 exclusion phecode
157 Pancreatic cancer Neoplasms 0.988 0.911 – 1.07 0.771 650 6541 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.02 0.953 – 1.08 0.64 1041 10580 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.987 0.96 – 1.01 0.345 5481 55346 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.991 0.852 – 1.15 0.912 184 1887 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.05 0.914 – 1.22 0.47 202 2040 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.01 0.866 – 1.17 0.932 191 1915 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 1.36 1.06 – 1.75 0.0165 57 596 exclusion phecode
165 Cancer within the respiratory system Neoplasms 0.957 0.92 – 0.995 0.027 2755 28033 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 0.927 0.886 – 0.969 0.000851 2182 22150 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 1.03 0.93 – 1.13 0.601 426 4334 exclusion phecode
170.1 Bone cancer Neoplasms 1.06 0.884 – 1.27 0.529 127 1301 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1 0.894 – 1.12 0.996 323 3282 exclusion phecode
172 Skin cancer Neoplasms 1.02 1 – 1.04 0.0197 13304 134124 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.973 0.935 – 1.01 0.18 2638 26635 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.972 0.935 – 1.01 0.169 2670 26956 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1.04 1.02 – 1.06 0.000202 10849 109317 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.931 0.858 – 1.01 0.0841 645 6604 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.05 0.9 – 1.22 0.541 178 1811 exclusion phecode
174 Breast cancer Neoplasms 1.01 0.992 – 1.03 0.253 12586 126010 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1.01 0.993 – 1.03 0.245 12381 123932 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.01 0.994 – 1.03 0.199 11662 116962 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.06 0.884 – 1.28 0.508 115 1143 exclusion phecode
175 Acquired absence of breast Neoplasms 1 0.961 – 1.05 0.909 2367 23895 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 0.96 0.918 – 1 0.0736 2155 21669 exclusion phecode
180.1 Cervical cancer Neoplasms 0.943 0.833 – 1.07 0.354 269 2709 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.965 0.922 – 1.01 0.126 2059 20713 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.999 0.943 – 1.06 0.977 1273 12764 exclusion phecode
184 Cancer of other female genital organs Neoplasms 0.973 0.921 – 1.03 0.344 1370 13711 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.956 0.895 – 1.02 0.192 962 9624 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.962 0.899 – 1.03 0.266 934 9343 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.971 0.861 – 1.09 0.629 302 3036 exclusion phecode
185 Cancer of prostate Neoplasms 0.998 0.972 – 1.03 0.891 5913 58312 exclusion phecode
187 Cancer of other male genital organs Neoplasms 1.01 0.914 – 1.11 0.857 437 4455 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.967 0.76 – 1.23 0.783 69 690 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 1.04 0.924 – 1.18 0.498 280 2854 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.946 0.773 – 1.16 0.591 104 1091 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.983 0.951 – 1.01 0.284 4097 41299 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.98 0.92 – 1.04 0.522 1062 10640 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.965 0.905 – 1.03 0.276 1022 10244 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.17 0.9 – 1.51 0.247 65 654 exclusion phecode
189.2 Cancer of bladder Neoplasms 0.972 0.932 – 1.01 0.192 2365 23928 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.976 0.933 – 1.02 0.286 2100 21283 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1 0.844 – 1.19 0.992 139 1434 exclusion phecode
190 Cancer of eye Neoplasms 0.961 0.822 – 1.12 0.618 173 1746 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.992 0.916 – 1.07 0.848 662 6831 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.954 0.873 – 1.04 0.295 550 5610 exclusion phecode
191.11 Cancer of brain Neoplasms 0.953 0.87 – 1.05 0.309 513 5203 exclusion phecode
193 Thyroid cancer Neoplasms 1.16 1.04 – 1.29 0.00755 333 3449 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.03 0.834 – 1.26 0.806 91 940 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.01 0.99 – 1.02 0.435 16565 165150 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.01 0.991 – 1.02 0.382 15880 159194 exclusion phecode
197 Chemotherapy Neoplasms 1 0.987 – 1.02 0.847 19987 212843 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 0.98 0.959 – 1 0.0654 9314 95319 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.994 0.966 – 1.02 0.657 5278 53584 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.968 0.927 – 1.01 0.15 2207 22623 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.964 0.915 – 1.02 0.173 1510 15470 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 0.945 0.907 – 0.984 0.00598 2607 26594 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.92 0.856 – 0.989 0.023 816 8457 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 0.966 0.924 – 1.01 0.135 2084 21561 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1 0.863 – 1.17 0.962 180 1888 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 0.974 0.921 – 1.03 0.362 1352 14291 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.08 0.88 – 1.31 0.479 93 948 exclusion phecode
200 Myeloproliferative disease Neoplasms 0.973 0.91 – 1.04 0.422 933 9911 exclusion phecode
200.1 Polycythemia vera Neoplasms 0.947 0.853 – 1.05 0.302 378 3867 exclusion phecode
201 Hodgkin's disease Neoplasms 1.09 0.892 – 1.33 0.398 97 2598 exclusion phecode
204 Leukemia Neoplasms 1 0.948 – 1.06 0.923 1299 16630 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1.04 0.945 – 1.15 0.39 416 5784 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.06 0.951 – 1.18 0.304 367 5084 exclusion phecode
204.2 Myeloid leukemia Neoplasms 0.981 0.886 – 1.09 0.716 393 4617 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.937 0.83 – 1.06 0.289 280 3287 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.1 0.912 – 1.32 0.329 124 1440 exclusion phecode
204.4 Multiple myeloma Neoplasms 0.998 0.904 – 1.1 0.963 421 5560 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1 0.988 – 1.02 0.762 19665 190656 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.949 0.888 – 1.01 0.118 965 9730 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1 0.976 – 1.03 0.79 5178 52158 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.04 0.934 – 1.16 0.46 343 3443 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.944 0.84 – 1.06 0.33 317 3169 exclusion phecode
214 Lipoma Neoplasms 1.01 0.987 – 1.04 0.315 6192 61966 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.03 0.998 – 1.06 0.0667 4558 45611 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.02 0.956 – 1.08 0.591 1092 11000 exclusion phecode
216 Benign neoplasm of skin Neoplasms 1.01 0.988 – 1.04 0.325 7604 76211 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.04 0.956 – 1.13 0.381 625 6277 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 1.03 0.949 – 1.12 0.463 588 5910 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.997 0.976 – 1.02 0.746 9980 99782 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 1 0.979 – 1.02 0.964 10199 101952 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.973 0.872 – 1.09 0.629 352 3529 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.934 0.884 – 0.987 0.0145 1440 14427 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.996 0.868 – 1.14 0.959 219 2188 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 1.11 0.946 – 1.3 0.205 159 1590 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.991 0.846 – 1.16 0.912 171 1713 exclusion phecode
224 Benign neoplasm of eye Neoplasms 1.14 0.951 – 1.36 0.159 127 1289 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.31 1.03 – 1.68 0.0308 66 673 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.945 0.878 – 1.02 0.126 807 8105 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.957 0.889 – 1.03 0.253 766 7707 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.785 0.602 – 1.02 0.0752 59 588 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.19 1.05 – 1.34 0.00523 259 2655 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.989 0.922 – 1.06 0.747 850 8583 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.07 0.921 – 1.24 0.387 182 1845 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.981 0.881 – 1.09 0.723 365 3684 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.954 0.848 – 1.07 0.432 308 3095 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.03 0.982 – 1.09 0.207 1577 15855 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.991 0.95 – 1.03 0.685 2375 23829 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.962 0.884 – 1.05 0.36 585 5983 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.944 0.886 – 1.01 0.0727 1079 11030 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.02 0.928 – 1.12 0.685 461 4679 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.9 0.829 – 0.977 0.0121 657 6741 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.974 0.928 – 1.02 0.28 1829 18418 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.932 0.846 – 1.03 0.153 452 4530 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.02 0.825 – 1.26 0.85 89 904 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 1.01 0.841 – 1.2 0.941 134 1369 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.01 0.992 – 1.03 0.275 14392 144314 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.979 0.919 – 1.04 0.503 1071 11014 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.13 0.925 – 1.38 0.228 99 1004 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.01 0.993 – 1.03 0.246 13741 138217 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.973 0.862 – 1.1 0.662 283 2855 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.02 0.89 – 1.17 0.758 214 2163 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.05 0.911 – 1.2 0.515 206 2084 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.01 0.907 – 1.11 0.921 389 3946 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.01 0.998 – 1.03 0.103 19551 184816 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.01 0.973 – 1.05 0.551 2726 27455 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.973 0.849 – 1.11 0.695 239 2372 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.14 0.909 – 1.43 0.258 76 764 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.08 0.986 – 1.19 0.0947 471 4712 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.07 0.908 – 1.26 0.414 156 1599 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.01 0.998 – 1.03 0.09 17610 169089 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.936 0.768 – 1.14 0.515 104 1046 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.05 0.91 – 1.21 0.502 197 2008 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.05 0.987 – 1.13 0.116 967 9827 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 0.969 0.883 – 1.06 0.51 489 5035 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 0.977 0.903 – 1.06 0.56 672 6779 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.01 0.893 – 1.14 0.887 263 2639 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.971 0.878 – 1.07 0.569 410 4151 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1 0.84 – 1.2 0.968 130 1305 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.986 0.881 – 1.1 0.813 344 3478 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.05 0.996 – 1.12 0.0693 1308 13229 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.05 0.979 – 1.12 0.181 911 9320 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.991 0.924 – 1.06 0.809 860 8666 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.993 0.922 – 1.07 0.86 769 7756 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.11 0.932 – 1.33 0.239 136 1406 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.977 0.903 – 1.06 0.573 662 6781 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.87 0.746 – 1.01 0.0753 187 1852 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.83 0.666 – 1.03 0.0956 95 940 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.03 0.911 – 1.17 0.607 255 2602 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.06 0.852 – 1.31 0.622 88 916 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.913 0.771 – 1.08 0.291 147 1565 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.941 0.866 – 1.02 0.146 625 6342 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.05 0.902 – 1.22 0.526 178 1788 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.04 0.843 – 1.27 0.736 102 1024 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.09 0.872 – 1.37 0.436 75 757 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.877 0.784 – 0.981 0.022 354 3600 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.878 0.785 – 0.983 0.0237 353 3588 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.929 0.813 – 1.06 0.279 240 2393 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.907 0.785 – 1.05 0.185 209 2085 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1.16 0.992 – 1.36 0.0622 155 1608 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.13 0.962 – 1.32 0.138 147 1530 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.977 0.807 – 1.18 0.815 101 1009 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 1.01 0.86 – 1.19 0.875 148 1493 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.06 0.915 – 1.23 0.441 196 2008 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.03 0.955 – 1.1 0.474 797 8264 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 0.974 0.917 – 1.03 0.397 1170 11901 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.961 0.891 – 1.04 0.313 734 7491 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1 0.911 – 1.11 0.93 438 4439 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.04 0.829 – 1.32 0.71 75 766 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.985 0.864 – 1.12 0.827 232 2398 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.05 0.935 – 1.17 0.423 327 3363 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.966 0.85 – 1.1 0.596 238 3008 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.01 0.88 – 1.17 0.855 196 2589 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.02 0.876 – 1.19 0.804 167 1895 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 0.905 0.736 – 1.11 0.348 101 1120 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.877 0.742 – 1.03 0.12 157 1594 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.828 0.692 – 0.991 0.0392 136 1385 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.01 1 – 1.02 0.0462 34441 234063 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.01 1 – 1.02 0.0485 34370 233834 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.01 1 – 1.02 0.0493 31952 226756 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.28 0.982 – 1.66 0.0684 58 575 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.906 0.767 – 1.07 0.241 162 1624 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.978 0.848 – 1.13 0.764 207 2091 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.994 0.961 – 1.03 0.727 3666 36958 exclusion phecode
274.1 Gout Endocrine/metabolic 0.999 0.963 – 1.04 0.969 3115 31475 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.996 0.823 – 1.2 0.966 112 1112 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.959 0.881 – 1.04 0.324 610 6072 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.939 0.859 – 1.03 0.16 555 5530 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.982 0.938 – 1.03 0.436 1987 20949 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.93 0.856 – 1.01 0.0823 634 6490 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.12 1 – 1.25 0.0509 351 3721 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.991 0.932 – 1.05 0.766 1119 11957 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.16 0.988 – 1.37 0.07 159 1710 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 0.977 0.953 – 1 0.067 7000 72501 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 0.983 0.951 – 1.02 0.304 3953 40686 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.998 0.87 – 1.14 0.978 227 2395 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.01 0.965 – 1.06 0.589 1778 18084 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 0.971 0.907 – 1.04 0.388 934 9669 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 0.966 0.913 – 1.02 0.22 1363 14146 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.997 0.938 – 1.06 0.932 1121 11559 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1 0.941 – 1.07 0.908 1018 10516 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 0.859 0.703 – 1.05 0.137 111 1118 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 0.969 0.931 – 1.01 0.115 2697 28099 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 0.872 0.786 – 0.967 0.00973 401 4489 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.13 0.949 – 1.34 0.17 127 1273 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.01 0.938 – 1.08 0.876 860 8922 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.1 0.989 – 1.22 0.0804 360 3577 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.984 0.855 – 1.13 0.827 227 2281 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.993 0.974 – 1.01 0.505 10722 107660 exclusion phecode
278.1 Obesity Endocrine/metabolic 0.993 0.973 – 1.01 0.483 10563 106041 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 0.916 0.733 – 1.14 0.438 83 834 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.958 0.736 – 1.25 0.75 65 659 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.953 0.827 – 1.1 0.506 211 2494 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.01 0.864 – 1.18 0.918 174 2084 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.05 0.871 – 1.28 0.585 114 1382 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.01 0.888 – 1.15 0.869 246 2459 exclusion phecode
280 Iron deficiency anemias Hematopoietic 0.963 0.94 – 0.986 0.00195 7503 75827 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.963 0.94 – 0.987 0.00252 7207 72818 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.973 0.883 – 1.07 0.574 445 4520 exclusion phecode
281 Other deficiency anemia Hematopoietic 0.936 0.88 – 0.996 0.0364 1093 11065 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 0.937 0.88 – 0.998 0.0426 1047 10608 exclusion phecode
281.11 Pernicious anemia Hematopoietic 0.959 0.891 – 1.03 0.275 739 7468 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.942 0.804 – 1.1 0.458 173 1757 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 0.884 0.758 – 1.03 0.12 179 1824 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.01 0.776 – 1.32 0.935 54 536 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.13 0.958 – 1.33 0.147 142 1491 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.03 0.787 – 1.34 0.844 54 557 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.21 0.972 – 1.5 0.0879 79 844 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.06 0.874 – 1.28 0.566 109 1371 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.973 0.777 – 1.22 0.809 81 1054 exclusion phecode
284 Aplastic anemia Hematopoietic 0.99 0.89 – 1.1 0.857 358 4337 exclusion phecode
285 Other anemias Hematopoietic 0.996 0.977 – 1.01 0.667 11774 120476 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.08 0.956 – 1.23 0.209 268 2695 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 0.965 0.891 – 1.05 0.383 661 6944 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.962 0.866 – 1.07 0.473 383 4129 exclusion phecode
286 Coagulation defects Hematopoietic 0.99 0.925 – 1.06 0.775 904 9162 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.96 0.872 – 1.06 0.402 456 4571 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.918 0.744 – 1.13 0.423 95 954 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.967 0.856 – 1.09 0.584 293 2931 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 0.987 0.767 – 1.27 0.917 62 626 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.893 0.715 – 1.11 0.315 85 854 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.03 0.923 – 1.14 0.616 376 3845 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.953 0.904 – 1 0.0724 1521 16429 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.12 0.938 – 1.34 0.208 125 1279 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 0.949 0.899 – 1 0.0617 1428 15444 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 0.949 0.855 – 1.05 0.332 389 4168 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.97 0.763 – 1.23 0.805 71 742 exclusion phecode
288 Diseases of white blood cells Hematopoietic 0.993 0.958 – 1.03 0.724 3136 37548 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.01 0.969 – 1.05 0.666 2569 31593 exclusion phecode
288.11 Neutropenia Hematopoietic 1.01 0.967 – 1.05 0.732 2577 31674 exclusion phecode
288.3 Eosinophilia Hematopoietic 1.3 1.02 – 1.65 0.0311 70 706 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.937 0.871 – 1.01 0.0836 787 8591 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.868 0.765 – 0.984 0.0272 273 2886 exclusion phecode
289.4 Lymphadenitis Hematopoietic 0.989 0.948 – 1.03 0.629 2246 25974 exclusion phecode
289.5 Diseases of spleen Hematopoietic 0.999 0.906 – 1.1 0.978 436 5138 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.02 0.902 – 1.15 0.773 281 2901 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 0.931 0.746 – 1.16 0.527 86 894 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.973 0.928 – 1.02 0.256 1899 19119 exclusion phecode
290.1 Dementias Mental Disorders 0.971 0.91 – 1.04 0.372 995 9949 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.959 0.868 – 1.06 0.416 424 4266 exclusion phecode
290.16 Vascular dementia Mental Disorders 0.929 0.801 – 1.08 0.331 200 1991 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.01 0.928 – 1.09 0.87 635 6449 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.841 0.658 – 1.08 0.168 69 705 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.988 0.919 – 1.06 0.732 818 8345 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.984 0.828 – 1.17 0.853 128 1317 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1 0.884 – 1.13 0.994 282 2847 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1 0.907 – 1.11 0.972 425 4358 exclusion phecode
292 Neurological disorders Mental Disorders 0.983 0.953 – 1.01 0.265 4510 45948 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.03 0.973 – 1.08 0.336 1478 14978 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 1.04 0.896 – 1.21 0.595 186 1886 exclusion phecode
292.3 Memory loss Mental Disorders 0.95 0.878 – 1.03 0.201 691 6933 exclusion phecode
292.4 Altered mental status Mental Disorders 0.969 0.926 – 1.01 0.162 2111 21680 exclusion phecode
292.6 Hallucinations Mental Disorders 0.948 0.84 – 1.07 0.384 295 3057 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.02 0.971 – 1.06 0.506 2062 20662 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.983 0.916 – 1.06 0.64 850 8949 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.04 0.969 – 1.12 0.281 834 8411 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.05 0.965 – 1.14 0.251 570 5744 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.04 0.889 – 1.21 0.638 176 1773 exclusion phecode
295.3 Psychosis Mental Disorders 1.01 0.862 – 1.18 0.917 167 1700 exclusion phecode
296 Mood disorders Mental Disorders 0.998 0.98 – 1.02 0.867 12245 123261 exclusion phecode
296.1 Bipolar Mental Disorders 1 0.94 – 1.07 0.967 1051 10553 exclusion phecode
296.2 Depression Mental Disorders 1 0.981 – 1.02 0.981 11613 116930 exclusion phecode
296.22 Major depressive disorder Mental Disorders 0.965 0.867 – 1.07 0.509 360 3583 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.03 0.917 – 1.16 0.604 305 3059 exclusion phecode
300 Anxiety disorders Mental Disorders 0.969 0.945 – 0.994 0.0145 6759 68132 exclusion phecode
300.1 Anxiety disorder Mental Disorders 0.968 0.943 – 0.993 0.0132 6244 62962 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 0.961 0.813 – 1.14 0.638 147 1492 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.01 0.939 – 1.1 0.718 701 7041 exclusion phecode
300.13 Phobia Mental Disorders 0.889 0.809 – 0.976 0.0137 496 4992 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.954 0.805 – 1.13 0.587 139 1403 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.2 0.918 – 1.58 0.18 53 525 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 0.941 0.787 – 1.12 0.502 124 1231 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.05 0.863 – 1.28 0.618 112 1127 exclusion phecode
301 Personality disorders Mental Disorders 0.996 0.891 – 1.11 0.937 332 3319 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.12 0.934 – 1.34 0.221 119 1184 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 1.01 0.894 – 1.15 0.853 279 2827 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.986 0.895 – 1.09 0.783 461 4656 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 1.02 0.91 – 1.14 0.771 346 3496 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.936 0.776 – 1.13 0.491 121 1222 exclusion phecode
304 Adjustment reaction Mental Disorders 1.06 0.943 – 1.19 0.326 293 2922 exclusion phecode
305.2 Eating disorder Mental Disorders 1.07 0.861 – 1.32 0.555 89 899 exclusion phecode
306 Other mental disorder Mental Disorders 0.986 0.974 – 0.998 0.0259 27618 228894 exclusion phecode
306.9 Tension headache Mental Disorders 0.933 0.829 – 1.05 0.252 313 3134 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 1.05 0.834 – 1.32 0.672 74 768 exclusion phecode
313.3 Autism Mental Disorders 1.01 0.767 – 1.32 0.961 51 537 exclusion phecode
315 Develomental delays and disorders Mental Disorders 0.983 0.881 – 1.1 0.753 345 3502 exclusion phecode
315.1 Learning disorder Mental Disorders 1.07 0.915 – 1.26 0.38 159 1604 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.935 0.746 – 1.17 0.558 87 875 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.01 0.987 – 1.04 0.303 5266 52825 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.846 0.637 – 1.12 0.25 54 596 exclusion phecode
317 Alcohol-related disorders Mental Disorders 0.987 0.969 – 1.01 0.166 12573 126132 exclusion phecode
317.1 Alcoholism Mental Disorders 0.975 0.954 – 0.997 0.024 8791 88354 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.03 0.955 – 1.1 0.491 831 8343 exclusion phecode
318 Tobacco use disorder Mental Disorders 0.985 0.971 – 1 0.0551 19162 184429 exclusion phecode
320 Meningitis Neurological 0.992 0.897 – 1.1 0.877 433 4427 exclusion phecode
323 Encephalitis Neurological 0.913 0.817 – 1.02 0.113 338 3405 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 0.844 0.673 – 1.06 0.14 74 736 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.01 0.899 – 1.15 0.812 286 2904 exclusion phecode
327 Sleep disorders Neurological 1.03 0.972 – 1.1 0.302 1149 11589 exclusion phecode
327.3 Sleep apnea Neurological 1.01 0.978 – 1.04 0.595 4397 44028 exclusion phecode
327.4 Insomnia Neurological 1.08 0.93 – 1.26 0.304 161 1651 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.1 0.93 – 1.3 0.263 135 1383 exclusion phecode
331 Other cerebral degenerations Neurological 0.957 0.899 – 1.02 0.16 1115 11353 exclusion phecode
331.1 Hydrocephalus Neurological 0.921 0.839 – 1.01 0.0852 487 4996 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 0.977 0.884 – 1.08 0.654 418 4269 exclusion phecode
332 Parkinson's disease Neurological 0.952 0.895 – 1.01 0.119 1111 11179 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.01 0.945 – 1.08 0.732 878 8892 exclusion phecode
333.1 Essential tremor Neurological 0.975 0.847 – 1.12 0.72 212 2145 exclusion phecode
333.2 Myoclonus Neurological 1.04 0.841 – 1.28 0.735 93 953 exclusion phecode
333.4 Torsion dystonia Neurological 1.06 0.933 – 1.21 0.357 249 2508 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 0.958 0.912 – 1.01 0.0835 1761 18012 exclusion phecode
334.1 Spinocerebellar disease Neurological 0.97 0.802 – 1.17 0.755 117 1165 exclusion phecode
334.2 Anterior horn cell disease Neurological 0.924 0.808 – 1.06 0.251 242 2422 exclusion phecode
335 Multiple sclerosis Neurological 0.782 0.737 – 0.83 3.8e-16 1330 13333 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 0.966 0.85 – 1.1 0.599 259 2652 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.14 0.913 – 1.42 0.248 71 717 exclusion phecode
338 Pain Neurological 0.984 0.913 – 1.06 0.675 753 7643 exclusion phecode
338.1 Acute pain Neurological 0.957 0.861 – 1.06 0.417 385 3909 exclusion phecode
338.2 Chronic pain Neurological 0.972 0.873 – 1.08 0.596 374 3795 exclusion phecode
339 Other headache syndromes Neurological 1.01 0.985 – 1.03 0.51 7701 77804 exclusion phecode
340 Migraine Neurological 0.98 0.943 – 1.02 0.318 2836 28479 exclusion phecode
340.1 Migrain with aura Neurological 0.922 0.797 – 1.07 0.276 208 2105 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.882 0.771 – 1.01 0.0684 250 2528 exclusion phecode
342 Hemiplegia Neurological 0.972 0.922 – 1.03 0.303 1478 14859 exclusion phecode
343 Infantile cerebral palsy Neurological 1.1 0.935 – 1.3 0.243 145 1445 exclusion phecode
344 Other paralytic syndromes Neurological 0.915 0.842 – 0.994 0.0355 638 6559 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.988 0.959 – 1.02 0.405 4962 49983 exclusion phecode
345.1 Epilepsy Neurological 0.978 0.91 – 1.05 0.533 850 8607 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.03 0.934 – 1.14 0.543 432 4365 exclusion phecode
345.12 Partial epilepsy Neurological 0.958 0.844 – 1.09 0.503 272 2759 exclusion phecode
345.3 Convulsions Neurological 0.994 0.952 – 1.04 0.785 2206 22209 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.04 0.874 – 1.24 0.652 134 1425 exclusion phecode
348 Other conditions of brain Neurological 0.928 0.861 – 1 0.0517 761 7761 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 0.938 0.824 – 1.07 0.329 263 2666 exclusion phecode
348.4 Cerebral cysts Neurological 0.936 0.783 – 1.12 0.468 130 1339 exclusion phecode
348.7 Coma Neurological 0.948 0.849 – 1.06 0.338 350 3568 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 0.981 0.86 – 1.12 0.776 240 2491 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 0.998 0.899 – 1.11 0.972 369 3870 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.926 0.826 – 1.04 0.189 330 3397 exclusion phecode
350 Abnormal movement Neurological 0.997 0.957 – 1.04 0.871 2600 26541 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.01 0.945 – 1.09 0.719 872 8799 exclusion phecode
350.2 Abnormality of gait Neurological 1 0.953 – 1.06 0.889 1548 15843 exclusion phecode
350.3 Lack of coordination Neurological 1 0.901 – 1.12 0.947 352 3606 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.02 0.769 – 1.35 0.887 54 537 exclusion phecode
351 Other peripheral nerve disorders Neurological 0.997 0.979 – 1.02 0.763 12325 123664 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.03 0.974 – 1.09 0.297 1340 13632 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.02 0.932 – 1.13 0.618 456 4612 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 0.998 0.931 – 1.07 0.951 858 8743 exclusion phecode
353 Nerve root and plexus disorders Neurological 0.938 0.882 – 0.998 0.0439 1113 11251 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.92 0.756 – 1.12 0.403 111 1131 exclusion phecode
353.2 Nerve root lesions Neurological 1.04 0.808 – 1.35 0.745 57 568 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.23 1.05 – 1.44 0.0117 148 1507 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.06 1.01 – 1.13 0.0309 1295 13555 exclusion phecode
358 Myoneural disorders Neurological 1.14 0.985 – 1.31 0.0809 209 2097 exclusion phecode
358.1 Myasthenia gravis Neurological 1.21 1.04 – 1.4 0.0131 191 1908 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 1.05 0.953 – 1.16 0.321 456 4621 exclusion phecode
359.1 Muscular dystrophies Neurological 1.03 0.849 – 1.24 0.783 121 1209 exclusion phecode
359.2 Myopathy Neurological 1.05 0.944 – 1.17 0.352 352 3579 exclusion phecode
360 Disorders of the globe Sense Organs 0.999 0.893 – 1.12 0.989 334 3354 exclusion phecode
360.2 Progressive myopia Sense Organs 0.992 0.872 – 1.13 0.896 250 2500 exclusion phecode
361 Retinal detachments and defects Sense Organs 1 0.968 – 1.04 0.844 3218 32249 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.01 0.951 – 1.06 0.838 1375 13811 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.907 0.708 – 1.16 0.437 67 676 exclusion phecode
362 Other retinal disorders Sense Organs 0.971 0.939 – 1 0.0874 3796 38118 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.973 0.931 – 1.02 0.236 2156 21669 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.975 0.932 – 1.02 0.257 2153 21641 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.01 0.856 – 1.19 0.914 161 1594 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1.01 0.824 – 1.25 0.897 99 978 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.952 0.886 – 1.02 0.179 843 8432 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.925 0.793 – 1.08 0.319 181 1814 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.13 0.905 – 1.4 0.288 80 802 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.89 0.731 – 1.08 0.248 116 1153 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.978 0.834 – 1.15 0.78 166 1689 exclusion phecode
363.3 Chorioretinal scars Sense Organs 1.09 0.838 – 1.42 0.517 69 685 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.02 0.939 – 1.1 0.662 637 6444 exclusion phecode
364.1 Corneal opacity Sense Organs 1.13 0.914 – 1.4 0.259 88 906 exclusion phecode
364.2 Corneal edema Sense Organs 0.865 0.689 – 1.09 0.21 79 795 exclusion phecode
364.4 Corneal degenerations Sense Organs 0.937 0.809 – 1.08 0.382 197 2007 exclusion phecode
364.41 Keratoconus Sense Organs 0.778 0.617 – 0.98 0.0333 83 865 exclusion phecode
364.5 Corneal dystrophy Sense Organs 1.02 0.886 – 1.18 0.774 210 2095 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 1.03 0.836 – 1.26 0.808 98 993 exclusion phecode
365 Glaucoma Sense Organs 1.02 0.985 – 1.05 0.321 4359 43824 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 1 0.943 – 1.07 0.879 1018 10258 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 1 0.94 – 1.07 0.941 1012 10199 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.02 0.943 – 1.1 0.65 693 6953 exclusion phecode
366 Cataract Sense Organs 1.01 0.992 – 1.02 0.353 19731 167562 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.942 0.738 – 1.2 0.63 68 693 exclusion phecode
366.2 Senile cataract Sense Organs 1 0.98 – 1.03 0.846 8149 81305 exclusion phecode
366.3 Traumatic cataract Sense Organs 1.05 0.856 – 1.28 0.655 100 1011 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.992 0.951 – 1.04 0.725 2379 23932 exclusion phecode
367.1 Myopia Sense Organs 0.957 0.902 – 1.01 0.141 1241 12432 exclusion phecode
367.2 Astigmatism Sense Organs 0.884 0.759 – 1.03 0.113 190 1885 exclusion phecode
367.8 Hypermetropia Sense Organs 1.1 0.969 – 1.25 0.138 253 2507 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.01 0.933 – 1.09 0.854 703 7153 exclusion phecode
368 Visual disturbances Sense Organs 0.99 0.953 – 1.03 0.617 2902 29468 exclusion phecode
368.1 Amblyopia Sense Organs 0.959 0.875 – 1.05 0.377 526 5290 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.06 0.982 – 1.14 0.134 706 7243 exclusion phecode
368.3 Anisometropia Sense Organs 0.979 0.827 – 1.16 0.807 152 1538 exclusion phecode
368.4 Visual field defects Sense Organs 1.09 0.977 – 1.22 0.12 327 3307 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.923 0.848 – 1.01 0.0682 597 6082 exclusion phecode
369 Infection of the eye Sense Organs 1.02 0.929 – 1.11 0.729 532 5520 exclusion phecode
369.2 Eye infection, viral Sense Organs 1.07 0.895 – 1.29 0.441 120 1250 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 1.07 0.927 – 1.23 0.362 203 2116 exclusion phecode
370 Keratitis Sense Organs 0.991 0.877 – 1.12 0.879 278 2843 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.956 0.806 – 1.13 0.604 138 1402 exclusion phecode
371 Inflammation of the eye Sense Organs 1 0.964 – 1.04 0.984 3016 30318 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.05 0.957 – 1.15 0.298 471 4791 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.992 0.95 – 1.03 0.699 2339 23434 exclusion phecode
372 Disorders of conjunctiva Sense Organs 0.995 0.923 – 1.07 0.893 740 7546 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.996 0.969 – 1.02 0.776 5631 56491 exclusion phecode
374.1 Ectropion or entropion Sense Organs 1 0.939 – 1.07 0.987 1045 10578 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.986 0.94 – 1.03 0.572 1813 18133 exclusion phecode
375 Disorders of lacrimal system Sense Organs 1.04 0.991 – 1.08 0.12 2174 21905 exclusion phecode
375.2 Epiphora Sense Organs 1.04 0.971 – 1.11 0.268 893 8903 exclusion phecode
376 Disorders of the orbit Sense Organs 0.867 0.686 – 1.1 0.235 77 854 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.841 0.751 – 0.941 0.00245 359 3602 exclusion phecode
377.1 Optic atrophy Sense Organs 0.898 0.681 – 1.19 0.448 55 569 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.809 0.669 – 0.979 0.0291 125 1242 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.01 0.959 – 1.07 0.636 1388 14047 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.99 0.924 – 1.06 0.766 899 9043 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.04 0.902 – 1.19 0.617 211 2126 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.09 0.963 – 1.22 0.177 264 2743 exclusion phecode
379 Other disorders of eye Sense Organs 0.999 0.965 – 1.03 0.934 3655 36783 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 1.01 0.953 – 1.07 0.79 1351 13561 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.965 0.919 – 1.01 0.15 1790 17993 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.14 0.889 – 1.46 0.3 70 707 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.09 0.979 – 1.2 0.121 396 4010 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.919 0.786 – 1.08 0.294 165 1684 exclusion phecode
380 Disorders of external ear Sense Organs 0.989 0.911 – 1.07 0.784 629 6359 exclusion phecode
380.1 Otitis externa Sense Organs 0.967 0.88 – 1.06 0.486 495 5089 exclusion phecode
380.4 Impacted cerumen Sense Organs 0.99 0.889 – 1.1 0.856 356 3596 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.03 0.982 – 1.07 0.248 2112 21369 exclusion phecode
381.1 Otitis media Sense Organs 1.02 0.976 – 1.08 0.325 1734 17569 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1 0.935 – 1.07 0.95 835 8479 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 1.09 0.944 – 1.26 0.239 192 1919 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 1.01 0.862 – 1.19 0.889 168 1695 exclusion phecode
381.9 Otorrhea Sense Organs 0.952 0.841 – 1.08 0.434 277 2799 exclusion phecode
382 Otalgia Sense Organs 1.15 1.02 – 1.29 0.0182 299 3075 exclusion phecode
383 Otosclerosis Sense Organs 0.893 0.793 – 1.01 0.0624 308 3073 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.06 1 – 1.12 0.048 1287 12929 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.03 0.967 – 1.1 0.361 1031 10378 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1 0.932 – 1.08 0.928 778 7796 exclusion phecode
385.3 Cholesteatoma Sense Organs 0.999 0.919 – 1.09 0.984 603 6046 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.03 0.905 – 1.17 0.661 239 2396 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.98 0.933 – 1.03 0.416 1719 17269 exclusion phecode
386.1 Meniere's disease Sense Organs 0.929 0.852 – 1.01 0.0916 573 5738 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 1.04 0.938 – 1.15 0.453 374 3737 exclusion phecode
386.3 Labyrinthitis Sense Organs 0.982 0.911 – 1.06 0.632 753 7622 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.991 0.961 – 1.02 0.553 4516 45528 exclusion phecode
388 Other disorders of ear Sense Organs 0.962 0.833 – 1.11 0.601 197 2008 exclusion phecode
389 Hearing loss Sense Organs 1 0.972 – 1.04 0.825 4131 41675 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 1.04 0.949 – 1.15 0.371 449 4533 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.01 0.918 – 1.11 0.82 448 4476 exclusion phecode
389.4 Tinnitus Sense Organs 0.998 0.911 – 1.09 0.973 501 5104 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.01 0.977 – 1.04 0.675 4800 48598 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.01 0.974 – 1.05 0.537 2934 29694 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.03 0.972 – 1.09 0.331 1254 12708 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 0.971 0.911 – 1.04 0.372 1030 10483 exclusion phecode
395 Heart valve disorders Circulatory System 0.982 0.951 – 1.01 0.261 4139 41898 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.993 0.956 – 1.03 0.726 2834 28677 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.992 0.878 – 1.12 0.901 268 2751 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.12 0.915 – 1.38 0.264 100 1030 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.901 0.729 – 1.11 0.337 95 965 exclusion phecode
395.6 Heart valve replaced Circulatory System 0.995 0.944 – 1.05 0.868 1471 14836 exclusion phecode
396 Abnormal heart sounds Circulatory System 0.992 0.932 – 1.06 0.812 1044 10411 exclusion phecode
401 Hypertension Circulatory System 0.998 0.99 – 1.01 0.662 73223 265716 exclusion phecode
401.1 Essential hypertension Circulatory System 0.998 0.99 – 1.01 0.673 73003 265500 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 0.974 0.928 – 1.02 0.282 1842 18912 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 0.955 0.858 – 1.06 0.405 366 3676 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.972 0.922 – 1.03 0.3 1492 15388 exclusion phecode
401.3 Other hypertensive complications Circulatory System 0.905 0.763 – 1.07 0.25 140 1430 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 0.967 0.917 – 1.02 0.229 1459 14693 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1 0.988 – 1.01 0.975 30879 209450 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.01 0.978 – 1.04 0.639 5100 51158 exclusion phecode
411.2 Myocardial infarction Circulatory System 0.999 0.98 – 1.02 0.908 11801 111905 exclusion phecode
411.3 Angina pectoris Circulatory System 1 0.988 – 1.02 0.641 15706 142799 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.01 0.99 – 1.02 0.498 19950 153628 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.01 0.932 – 1.09 0.845 693 6965 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.995 0.978 – 1.01 0.531 15067 130901 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.978 0.921 – 1.04 0.473 1201 12074 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 0.993 0.946 – 1.04 0.761 1781 18090 exclusion phecode
414.2 ASCVD Circulatory System 1.15 0.903 – 1.47 0.257 69 712 exclusion phecode
415 Pulmonary heart disease Circulatory System 0.995 0.965 – 1.03 0.75 4363 44532 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.957 0.759 – 1.21 0.713 74 743 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.02 0.939 – 1.11 0.64 587 5961 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.01 0.92 – 1.11 0.8 437 4444 exclusion phecode
416 Cardiomegaly Circulatory System 0.97 0.931 – 1.01 0.132 2641 26598 exclusion phecode
418 Nonspecific chest pain Circulatory System 1 0.988 – 1.01 0.995 28285 268611 exclusion phecode
418.1 Precordial pain Circulatory System 1.01 0.971 – 1.04 0.763 3515 35333 exclusion phecode
420 Carditis Circulatory System 0.967 0.924 – 1.01 0.152 2062 20893 exclusion phecode
420.1 Myocarditis Circulatory System 0.914 0.763 – 1.09 0.328 126 1253 exclusion phecode
420.2 Pericarditis Circulatory System 0.97 0.916 – 1.03 0.294 1309 13279 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.02 0.887 – 1.17 0.782 216 2209 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.11 0.915 – 1.34 0.297 111 1119 exclusion phecode
420.3 Endocarditis Circulatory System 0.999 0.925 – 1.08 0.977 705 7136 exclusion phecode
425 Cardiomyopathy Circulatory System 0.971 0.915 – 1.03 0.332 1244 12611 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.973 0.916 – 1.03 0.364 1211 12264 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.06 0.885 – 1.27 0.528 129 1322 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.11 0.943 – 1.3 0.213 162 1622 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.04 0.797 – 1.36 0.76 60 599 exclusion phecode
426 Cardiac conduction disorders Circulatory System 0.998 0.973 – 1.02 0.857 6811 68652 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 0.991 0.947 – 1.04 0.705 2086 20992 exclusion phecode
426.21 First degree AV block Circulatory System 1.02 0.952 – 1.09 0.606 976 9788 exclusion phecode
426.23 Second degree AV block Circulatory System 0.915 0.828 – 1.01 0.0815 444 4479 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1 0.92 – 1.09 0.957 579 5823 exclusion phecode
426.25 Other heart block Circulatory System 0.977 0.813 – 1.17 0.801 129 1312 exclusion phecode
426.3 Bundle branch block Circulatory System 1 0.966 – 1.04 0.924 3276 33128 exclusion phecode
426.31 Right bundle branch block Circulatory System 1 0.949 – 1.06 0.949 1466 14835 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.02 0.973 – 1.07 0.389 1718 17380 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.923 0.806 – 1.06 0.25 232 2315 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.02 0.782 – 1.33 0.886 59 597 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.994 0.953 – 1.04 0.775 2443 24573 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.992 0.949 – 1.04 0.708 2246 22578 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 0.986 0.973 – 0.999 0.0418 23864 204819 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 0.975 0.94 – 1.01 0.188 3159 31815 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.967 0.926 – 1.01 0.132 2309 23343 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.996 0.931 – 1.07 0.914 932 9281 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 0.989 0.972 – 1.01 0.198 14418 132603 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.97 0.935 – 1.01 0.104 3197 32058 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.01 0.948 – 1.07 0.827 1172 11824 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.06 0.944 – 1.18 0.346 339 3410 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.03 0.961 – 1.1 0.435 973 9814 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.982 0.919 – 1.05 0.6 941 9486 exclusion phecode
427.6 Premature beats Circulatory System 0.958 0.875 – 1.05 0.348 530 5325 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 0.964 0.799 – 1.16 0.703 116 1158 exclusion phecode
427.7 Tachycardia NOS Circulatory System 0.999 0.956 – 1.04 0.975 2116 21742 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.03 0.928 – 1.14 0.589 399 3997 exclusion phecode
427.9 Palpitations Circulatory System 0.998 0.965 – 1.03 0.919 3776 37921 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.994 0.967 – 1.02 0.676 5462 55580 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 0.971 0.928 – 1.02 0.207 2047 20927 exclusion phecode
428.2 Heart failure NOS Circulatory System 0.993 0.963 – 1.02 0.671 4345 44197 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 0.996 0.923 – 1.08 0.923 707 7126 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.09 0.842 – 1.41 0.517 62 635 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.98 0.895 – 1.07 0.655 515 5182 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.01 0.873 – 1.16 0.913 194 1963 exclusion phecode
430 Intracranial hemorrhage Circulatory System 0.982 0.937 – 1.03 0.464 1853 18711 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.966 0.9 – 1.04 0.343 827 8305 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 0.994 0.923 – 1.07 0.876 755 7600 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.02 0.896 – 1.15 0.8 255 2639 exclusion phecode
433 Cerebrovascular disease Circulatory System 0.986 0.964 – 1.01 0.2 8636 86810 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.01 0.954 – 1.07 0.689 1166 11734 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.01 0.88 – 1.16 0.903 222 2247 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.978 0.948 – 1.01 0.175 4179 41980 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.964 0.917 – 1.01 0.158 1657 16655 exclusion phecode
433.3 Cerebral ischemia Circulatory System 0.962 0.925 – 1 0.0504 2854 28777 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 0.964 0.922 – 1.01 0.116 2113 21223 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.01 0.916 – 1.12 0.792 390 3905 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.985 0.93 – 1.04 0.618 1263 12684 exclusion phecode
440 Atherosclerosis Circulatory System 1.02 0.965 – 1.08 0.495 1362 13735 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.02 0.847 – 1.24 0.808 111 1119 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.05 0.974 – 1.12 0.216 797 8008 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 0.991 0.879 – 1.12 0.888 279 2850 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.01 0.929 – 1.1 0.812 600 6118 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.03 0.91 – 1.16 0.644 278 2811 exclusion phecode
442 Other aneurysm Circulatory System 1.01 0.959 – 1.05 0.826 1863 18821 exclusion phecode
442.1 Aortic aneurysm Circulatory System 0.995 0.942 – 1.05 0.86 1433 14506 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.03 0.959 – 1.1 0.457 915 9266 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 0.95 0.778 – 1.16 0.615 99 1010 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.934 0.796 – 1.1 0.407 166 1681 exclusion phecode
442.4 Arterial dissection Circulatory System 1.13 0.873 – 1.46 0.353 54 547 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.01 0.872 – 1.17 0.912 201 2014 exclusion phecode
443 Peripheral vascular disease Circulatory System 0.991 0.959 – 1.02 0.588 3856 38967 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 0.956 0.898 – 1.02 0.151 1123 11369 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.02 0.919 – 1.14 0.679 376 3846 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 0.988 0.955 – 1.02 0.499 3627 36612 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.01 0.967 – 1.05 0.736 2540 25619 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 0.979 0.914 – 1.05 0.557 900 9177 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.999 0.913 – 1.09 0.975 541 5500 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.02 0.947 – 1.09 0.641 816 8189 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.966 0.833 – 1.12 0.653 187 1870 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.01 0.914 – 1.12 0.801 387 3860 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.11 0.974 – 1.27 0.118 237 2384 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 0.952 0.898 – 1.01 0.0964 1306 13216 exclusion phecode
447.1 Stricture of artery Circulatory System 0.957 0.891 – 1.03 0.231 853 8649 exclusion phecode
448 Disease of capillaries Circulatory System 1.03 0.875 – 1.22 0.69 138 1416 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.06 0.981 – 1.15 0.136 666 6994 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1 0.97 – 1.04 0.869 3863 39441 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1 0.967 – 1.04 0.962 3598 36750 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 0.957 0.875 – 1.05 0.342 530 5608 exclusion phecode
454 Varicose veins Circulatory System 0.997 0.978 – 1.02 0.765 11095 111474 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1 0.983 – 1.02 0.851 11422 114669 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.967 0.891 – 1.05 0.427 619 6285 exclusion phecode
455 Hemorrhoids Circulatory System 0.997 0.983 – 1.01 0.614 23264 233297 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.925 0.795 – 1.08 0.317 183 1851 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.02 0.824 – 1.25 0.881 96 966 exclusion phecode
458 Hypotension Circulatory System 0.973 0.946 – 1 0.054 5574 57440 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.01 0.951 – 1.07 0.807 1296 13276 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 0.948 0.826 – 1.09 0.452 225 2333 exclusion phecode
458.9 Hypotension NOS Circulatory System 0.962 0.928 – 0.996 0.031 3373 34794 exclusion phecode
459 Other disorders of circulatory system Circulatory System 0.994 0.978 – 1.01 0.506 15959 159852 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.07 0.909 – 1.26 0.41 137 1407 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 0.993 0.976 – 1.01 0.37 15815 158491 exclusion phecode
464 Acute sinusitis Respiratory 1.03 0.886 – 1.19 0.724 190 1943 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.04 0.991 – 1.08 0.12 2193 22686 exclusion phecode
465.2 Acute pharyngitis Respiratory 1.04 0.969 – 1.12 0.271 783 8304 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 1 0.851 – 1.18 0.999 162 1636 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.02 0.985 – 1.05 0.329 4616 46322 exclusion phecode
471 Nasal polyps Respiratory 1.09 1.06 – 1.13 5.89e-07 3280 32757 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.02 0.955 – 1.09 0.549 951 9537 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.02 0.979 – 1.06 0.343 2516 25372 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.04 0.857 – 1.27 0.664 102 1031 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.02 0.903 – 1.16 0.722 257 2630 exclusion phecode
473.4 Voice disturbance Respiratory 1.01 0.945 – 1.07 0.867 1069 10721 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1.03 0.976 – 1.08 0.317 1736 17639 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.05 0.96 – 1.14 0.305 542 5463 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.04 0.976 – 1.1 0.241 1092 11152 exclusion phecode
475 Chronic sinusitis Respiratory 1.1 1.06 – 1.15 3.19e-06 2552 25749 exclusion phecode
476 Allergic rhinitis Respiratory 0.982 0.921 – 1.05 0.585 1045 10514 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 0.99 0.95 – 1.03 0.65 2400 24308 exclusion phecode
478 Throat pain Respiratory 1 0.9 – 1.11 0.985 374 3772 exclusion phecode
479 Other upper respiratory disease Respiratory 1 0.97 – 1.04 0.901 4014 40529 exclusion phecode
480 Pneumonia Respiratory 0.989 0.969 – 1.01 0.316 9909 102817 exclusion phecode
480.1 Bacterial pneumonia Respiratory 0.98 0.955 – 1.01 0.119 6343 66033 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 0.98 0.954 – 1.01 0.154 5620 58515 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 0.867 0.7 – 1.07 0.189 89 921 exclusion phecode
480.2 Viral pneumonia Respiratory 1.13 0.88 – 1.44 0.345 64 716 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.912 0.724 – 1.15 0.435 81 980 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.02 0.95 – 1.1 0.542 755 7904 exclusion phecode
481 Influenza Respiratory 0.939 0.832 – 1.06 0.307 293 3265 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.925 0.794 – 1.08 0.314 187 1921 exclusion phecode
495 Asthma Respiratory 1 0.988 – 1.01 0.917 25456 249120 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.02 0.897 – 1.16 0.772 246 2492 exclusion phecode
496 Chronic airway obstruction Respiratory 0.997 0.977 – 1.02 0.79 10237 100904 exclusion phecode
496.1 Emphysema Respiratory 0.98 0.933 – 1.03 0.42 1705 17309 exclusion phecode
496.2 Chronic bronchitis Respiratory 0.991 0.954 – 1.03 0.641 2897 29280 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 0.996 0.957 – 1.04 0.854 2656 26885 exclusion phecode
496.3 Bronchiectasis Respiratory 1.02 0.975 – 1.07 0.359 1819 18738 exclusion phecode
497 Bronchitis Respiratory 0.997 0.918 – 1.08 0.945 613 6231 exclusion phecode
500 Lung disease due to external agents Respiratory 1.04 0.938 – 1.15 0.474 400 4070 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.3 1.06 – 1.61 0.0139 78 780 exclusion phecode
500.2 Pneumoconiosis Respiratory 0.964 0.843 – 1.1 0.587 237 2389 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.01 0.932 – 1.1 0.798 637 6516 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.03 0.959 – 1.1 0.443 880 9131 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 0.945 0.86 – 1.04 0.237 478 5042 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.01 0.897 – 1.13 0.884 313 3262 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.06 0.817 – 1.37 0.664 59 607 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.06 0.992 – 1.12 0.0872 1104 11296 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1 0.976 – 1.03 0.873 6132 63877 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.04 0.992 – 1.09 0.103 1917 19827 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.974 0.935 – 1.01 0.206 2504 25873 exclusion phecode
509.1 Respiratory failure Respiratory 0.972 0.928 – 1.02 0.225 1989 20579 exclusion phecode
509.2 Respiratory insufficiency Respiratory 0.978 0.931 – 1.03 0.377 1734 17987 exclusion phecode
509.5 Respiratory arrest Respiratory 1.07 0.903 – 1.28 0.418 139 1422 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.01 0.906 – 1.12 0.92 376 3839 exclusion phecode
510 Other diseases of lung Respiratory 0.988 0.915 – 1.07 0.762 717 7509 exclusion phecode
512 Other symptoms of respiratory system Respiratory 0.995 0.974 – 1.02 0.661 8779 89853 exclusion phecode
512.1 Wheezing Respiratory 1.06 0.925 – 1.22 0.39 214 2187 exclusion phecode
512.2 Painful respiration Respiratory 1 0.866 – 1.16 0.979 201 2064 exclusion phecode
512.7 Shortness of breath Respiratory 1 0.976 – 1.03 0.831 5702 58163 exclusion phecode
512.8 Cough Respiratory 0.975 0.937 – 1.01 0.207 2734 28494 exclusion phecode
512.9 Other dyspnea Respiratory 1.01 0.944 – 1.08 0.764 902 9063 exclusion phecode
513 Respiratory abnormalities Respiratory 1.03 0.948 – 1.12 0.495 599 6075 exclusion phecode
513.3 Hypoventilation Respiratory 0.976 0.779 – 1.22 0.833 81 822 exclusion phecode
513.4 Hyperventilation Respiratory 1.02 0.906 – 1.16 0.699 272 2762 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.12 0.947 – 1.32 0.188 149 1526 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 0.991 0.95 – 1.03 0.69 2367 24508 exclusion phecode
516 Abnormal sputum Respiratory 1.03 0.98 – 1.07 0.274 2090 21193 exclusion phecode
516.1 Hemoptysis Respiratory 1.01 0.968 – 1.06 0.568 2036 20608 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.997 0.976 – 1.02 0.816 9014 93133 exclusion phecode
519.2 Respiratory complications Respiratory 1 0.895 – 1.12 0.958 314 3260 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1 0.978 – 1.02 0.993 8521 88014 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.03 0.912 – 1.16 0.654 289 3027 exclusion phecode
520 Disorders of tooth development Digestive 0.993 0.949 – 1.04 0.777 2022 20264 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.06 0.802 – 1.4 0.681 52 526 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.99 0.949 – 1.03 0.634 2337 23447 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 0.993 0.956 – 1.03 0.701 2980 30087 exclusion phecode
521.1 Dental caries Digestive 0.992 0.956 – 1.03 0.687 2990 30195 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.03 0.984 – 1.08 0.191 1754 17664 exclusion phecode
522.5 Periapical abscess Digestive 1.03 0.965 – 1.09 0.415 1153 11675 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.02 0.972 – 1.07 0.389 1664 16738 exclusion phecode
523.1 Gingivitis Digestive 0.99 0.813 – 1.21 0.922 109 1119 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.02 0.957 – 1.08 0.607 1160 11609 exclusion phecode
523.31 Acute periodontitis Digestive 1.01 0.933 – 1.1 0.785 663 6645 exclusion phecode
523.32 Chronic periodontitis Digestive 1.02 0.937 – 1.11 0.627 558 5575 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.2 1.07 – 1.33 0.00142 330 3297 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.25 1.12 – 1.4 0.000122 304 3036 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.997 0.958 – 1.04 0.901 2630 26577 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.26 0.989 – 1.6 0.062 70 715 exclusion phecode
526 Diseases of the jaws Digestive 0.993 0.928 – 1.06 0.843 913 9235 exclusion phecode
526.1 Cysts of the jaws Digestive 0.882 0.785 – 0.991 0.0353 326 3271 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.07 0.834 – 1.38 0.58 61 607 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.06 0.933 – 1.21 0.369 237 2398 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.05 0.924 – 1.2 0.436 230 2327 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 1.02 0.836 – 1.24 0.845 106 1092 exclusion phecode
526.9 Jaw disease NOS Digestive 1.02 0.888 – 1.16 0.822 228 2318 exclusion phecode
527 Diseases of the salivary glands Digestive 1.03 0.953 – 1.11 0.453 666 6910 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 0.885 0.705 – 1.11 0.292 80 833 exclusion phecode
527.2 Sialoadenitis Digestive 1.06 0.954 – 1.18 0.277 360 3641 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 0.966 0.747 – 1.25 0.789 62 615 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 0.979 0.806 – 1.19 0.827 112 1193 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.01 0.976 – 1.04 0.596 3783 38534 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.05 0.948 – 1.15 0.372 425 4647 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.982 0.882 – 1.09 0.747 350 3858 exclusion phecode
528.12 Oral aphthae Digestive 1.37 1.1 – 1.71 0.00486 79 835 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.04 0.888 – 1.21 0.657 175 1781 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 1.1 0.916 – 1.32 0.311 119 1210 exclusion phecode
528.41 Cyst of the salivary gland Digestive 1.17 0.95 – 1.43 0.142 92 936 exclusion phecode
528.5 Diseases of lips Digestive 0.96 0.888 – 1.04 0.31 671 6790 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 0.96 0.853 – 1.08 0.496 307 3058 exclusion phecode
528.7 Sialolithiasis Digestive 1.01 0.904 – 1.14 0.823 313 3119 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.02 0.959 – 1.08 0.562 1202 12244 exclusion phecode
529.1 Glossitis Digestive 1.08 0.959 – 1.22 0.2 286 2971 exclusion phecode
530 Diseases of esophagus Digestive 1.01 0.994 – 1.02 0.375 33133 277674 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.01 0.996 – 1.02 0.202 30955 270964 exclusion phecode
530.11 GERD Digestive 1 0.989 – 1.02 0.66 22422 224608 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.03 0.999 – 1.06 0.0605 5141 51710 exclusion phecode
530.14 Reflux esophagitis Digestive 1 0.982 – 1.02 0.829 10343 103880 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.972 0.923 – 1.02 0.269 1662 16699 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 0.999 0.952 – 1.05 0.97 1839 18550 exclusion phecode
530.5 Disorders of esophageal motility Digestive 0.901 0.828 – 0.979 0.0145 631 6316 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.9 0.763 – 1.06 0.211 151 1515 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.93 0.832 – 1.04 0.208 338 3396 exclusion phecode
530.9 Heartburn Digestive 1.01 0.969 – 1.06 0.556 2067 20771 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.983 0.959 – 1.01 0.179 7005 70602 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.959 0.883 – 1.04 0.314 621 6332 exclusion phecode
531.2 Gastric ulcer Digestive 0.966 0.935 – 0.998 0.0386 4029 40680 exclusion phecode
531.3 Duodenal ulcer Digestive 0.995 0.958 – 1.03 0.797 2961 29796 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.15 1.04 – 1.26 0.0069 419 4239 exclusion phecode
532 Dysphagia Digestive 1.01 0.981 – 1.03 0.593 6331 63975 exclusion phecode
535 Gastritis and duodenitis Digestive 0.985 0.973 – 0.998 0.0209 27772 260104 exclusion phecode
535.1 Acute gastritis Digestive 0.979 0.921 – 1.04 0.479 1174 11766 exclusion phecode
535.2 Atrophic gastritis Digestive 1.01 0.906 – 1.12 0.867 364 3654 exclusion phecode
535.6 Duodenitis Digestive 0.988 0.965 – 1.01 0.324 7506 75484 exclusion phecode
535.8 Other specified gastritis Digestive 0.984 0.961 – 1.01 0.163 7977 80268 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.04 0.863 – 1.24 0.701 117 1184 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.02 0.899 – 1.17 0.723 255 2567 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 0.983 0.949 – 1.02 0.348 3336 33713 exclusion phecode
540 Appendiceal conditions Digestive 0.987 0.951 – 1.02 0.504 3068 30730 exclusion phecode
540.1 Appendicitis Digestive 0.986 0.948 – 1.02 0.465 2876 28817 exclusion phecode
540.11 Acute appendicitis Digestive 0.979 0.94 – 1.02 0.315 2586 25875 exclusion phecode
550 Abdominal hernia Digestive 0.994 0.984 – 1 0.239 45043 281107 exclusion phecode
550.1 Inguinal hernia Digestive 0.997 0.98 – 1.01 0.724 15678 122407 exclusion phecode
550.2 Diaphragmatic hernia Digestive 0.992 0.98 – 1 0.224 26242 237576 exclusion phecode
550.3 Femoral hernia Digestive 0.965 0.889 – 1.05 0.396 648 6468 exclusion phecode
550.4 Umbilical hernia Digestive 0.986 0.953 – 1.02 0.43 3675 36834 exclusion phecode
550.5 Ventral hernia Digestive 1.02 0.981 – 1.05 0.388 3392 34112 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 0.986 0.956 – 1.02 0.371 4391 44242 exclusion phecode
555.1 Regional enteritis Digestive 0.952 0.905 – 1 0.0531 1714 17267 exclusion phecode
555.2 Ulcerative colitis Digestive 1 0.964 – 1.04 0.995 3140 31647 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 0.925 0.847 – 1.01 0.0865 532 5350 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.02 0.957 – 1.09 0.54 1040 10548 exclusion phecode
556.1 Ulceration of intestine Digestive 1.01 0.93 – 1.09 0.856 659 6690 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.898 0.795 – 1.02 0.0868 287 2977 exclusion phecode
557.1 Celiac disease Digestive 0.75 0.713 – 0.79 4.78e-28 1809 18323 exclusion phecode
558 Noninfectious gastroenteritis Digestive 0.983 0.967 – 0.999 0.0428 15200 154449 exclusion phecode
559 Ileostomy status Digestive 1.03 0.98 – 1.08 0.243 1626 16462 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 0.965 0.933 – 0.998 0.0356 3858 39146 exclusion phecode
560.1 Paralytic ileus Digestive 1.02 0.927 – 1.11 0.737 508 5205 exclusion phecode
560.2 Impaction of intestine Digestive 1.03 0.907 – 1.17 0.656 263 2658 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.949 0.883 – 1.02 0.157 823 8275 exclusion phecode
560.4 Other intestinal obstruction Digestive 0.964 0.93 – 0.999 0.0454 3297 33389 exclusion phecode
561 Symptoms involving digestive system Digestive 0.995 0.979 – 1.01 0.569 15616 157017 exclusion phecode
561.1 Diarrhea Digestive 0.971 0.881 – 1.07 0.543 458 4626 exclusion phecode
561.2 Flatulence Digestive 0.989 0.941 – 1.04 0.669 1664 16775 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 0.987 0.975 – 1 0.0529 26450 210703 exclusion phecode
562.1 Diverticulosis Digestive 0.988 0.975 – 1 0.0564 26409 210654 exclusion phecode
563 Constipation Digestive 0.998 0.978 – 1.02 0.871 10068 102654 exclusion phecode
564 Functional digestive disorders Digestive 0.998 0.984 – 1.01 0.733 21388 209005 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 0.999 0.972 – 1.03 0.947 5467 54903 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1 0.955 – 1.06 0.856 1597 16368 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 0.996 0.979 – 1.01 0.606 15007 150889 exclusion phecode
565 Anal and rectal conditions Digestive 1.01 0.995 – 1.03 0.162 14609 146664 exclusion phecode
565.1 Anal and rectal polyp Digestive 1.01 0.984 – 1.03 0.543 7286 73060 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 0.994 0.928 – 1.06 0.867 901 9253 exclusion phecode
568 Other disorders of peritoneum Digestive 1 0.966 – 1.04 0.935 3225 32423 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.01 0.977 – 1.05 0.47 3068 30823 exclusion phecode
569 Other disorders of intestine Digestive 0.981 0.95 – 1.01 0.232 4107 41679 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.02 0.862 – 1.22 0.784 140 1467 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.01 0.918 – 1.11 0.848 477 4837 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.03 0.99 – 1.07 0.145 2893 29469 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.02 0.974 – 1.08 0.358 1661 16825 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.816 0.668 – 0.996 0.0453 110 1135 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.04 0.918 – 1.19 0.51 251 2551 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.05 0.986 – 1.13 0.124 944 9751 exclusion phecode
571.81 Portal hypertension Digestive 1.01 0.919 – 1.1 0.911 516 5258 exclusion phecode
572 Ascites (non malignant) Digestive 0.97 0.919 – 1.02 0.268 1489 15376 exclusion phecode
573 Other disorders of liver Digestive 1.01 0.957 – 1.07 0.703 1458 14900 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.06 0.862 – 1.3 0.588 92 956 exclusion phecode
573.3 Hepatomegaly Digestive 0.99 0.874 – 1.12 0.877 275 2951 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 0.982 0.915 – 1.05 0.601 872 8894 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 0.985 0.951 – 1.02 0.414 3358 34404 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 0.894 0.772 – 1.04 0.135 203 2067 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 0.993 0.977 – 1.01 0.433 15450 155288 exclusion phecode
574.1 Cholelithiasis Digestive 0.99 0.973 – 1.01 0.286 13420 134809 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.971 0.921 – 1.02 0.287 1491 14982 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.98 0.953 – 1.01 0.165 5384 54042 exclusion phecode
574.2 Calculus of bile duct Digestive 0.984 0.945 – 1.02 0.426 2590 26041 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1 0.963 – 1.04 0.928 2716 27361 exclusion phecode
575 Other biliary tract disease Digestive 0.964 0.932 – 0.997 0.0316 3804 38528 exclusion phecode
575.1 Cholangitis Digestive 0.875 0.795 – 0.964 0.00673 482 4912 exclusion phecode
575.2 Obstruction of bile duct Digestive 1 0.931 – 1.08 0.913 750 7709 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.965 0.876 – 1.06 0.467 456 4551 exclusion phecode
575.7 Other disorders of gallbladder Digestive 0.982 0.93 – 1.04 0.51 1394 14041 exclusion phecode
575.8 Other disorders of biliary tract Digestive 0.956 0.896 – 1.02 0.172 1017 10316 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.977 0.871 – 1.1 0.691 340 3471 exclusion phecode
577 Diseases of pancreas Digestive 1 0.962 – 1.04 0.929 2623 26509 exclusion phecode
577.1 Acute pancreatitis Digestive 1.01 0.961 – 1.05 0.794 1974 19838 exclusion phecode
577.2 Chronic pancreatitis Digestive 0.958 0.874 – 1.05 0.364 509 5118 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.05 0.942 – 1.17 0.386 359 3628 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1 0.99 – 1.02 0.532 20446 205158 exclusion phecode
578.1 Hematemesis Digestive 1.02 0.974 – 1.07 0.395 1932 19456 exclusion phecode
578.2 Blood in stool Digestive 0.994 0.954 – 1.03 0.76 2578 26135 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1 0.986 – 1.02 0.631 12985 130065 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.02 0.991 – 1.05 0.189 5217 52489 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.03 0.972 – 1.08 0.355 1417 15417 exclusion phecode
579.2 Splenomegaly Digestive 1.02 0.915 – 1.14 0.694 339 4226 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.994 0.945 – 1.05 0.818 1638 16453 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1 0.947 – 1.05 0.99 1486 15257 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.01 0.95 – 1.08 0.681 1017 10475 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.994 0.778 – 1.27 0.959 74 733 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.86 0.713 – 1.04 0.114 130 1355 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.03 0.961 – 1.11 0.393 846 8708 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.95 0.861 – 1.05 0.303 455 4665 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.954 0.834 – 1.09 0.498 238 2446 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.947 0.828 – 1.08 0.422 245 2514 exclusion phecode
585 Renal failure Genitourinary 0.959 0.935 – 0.983 0.00107 6675 69327 exclusion phecode
585.1 Acute renal failure Genitourinary 0.945 0.915 – 0.975 0.000395 4313 45015 exclusion phecode
585.2 Renal failure NOS Genitourinary 0.954 0.903 – 1.01 0.0939 1394 14551 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.948 0.91 – 0.988 0.0108 2558 26319 exclusion phecode
585.31 Renal dialysis Genitourinary 1.04 0.943 – 1.14 0.465 478 4920 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 0.986 0.951 – 1.02 0.432 3274 33396 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.915 0.791 – 1.06 0.23 200 2073 exclusion phecode
586.11 Small kidney Genitourinary 0.959 0.819 – 1.12 0.607 171 1785 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 0.996 0.939 – 1.06 0.894 1237 12498 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.805 0.637 – 1.02 0.0691 78 796 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.02 0.949 – 1.09 0.635 891 9072 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.04 0.933 – 1.16 0.485 356 3653 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 0.977 0.793 – 1.2 0.825 94 982 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 0.989 0.812 – 1.2 0.911 114 1150 exclusion phecode
590 Pyelonephritis Genitourinary 1.02 0.961 – 1.08 0.559 1305 13223 exclusion phecode
591 Urinary tract infection Genitourinary 0.984 0.966 – 1 0.0972 12178 123241 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.01 0.97 – 1.05 0.683 2938 29496 exclusion phecode
592.1 Cystitis Genitourinary 1.01 0.975 – 1.05 0.512 2877 28872 exclusion phecode
592.11 Acute cystitis Genitourinary 1.08 0.909 – 1.29 0.368 136 1365 exclusion phecode
592.12 Chronic cystitis Genitourinary 1.01 0.942 – 1.08 0.772 880 8833 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.06 0.934 – 1.21 0.358 245 2472 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.07 0.908 – 1.25 0.431 164 1660 exclusion phecode
593 Hematuria Genitourinary 1.01 0.995 – 1.03 0.18 15916 159234 exclusion phecode
594 Urinary calculus Genitourinary 1 0.978 – 1.03 0.783 6325 63363 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.02 0.984 – 1.06 0.27 3147 31557 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 0.977 0.906 – 1.05 0.539 768 7699 exclusion phecode
594.3 Calculus of ureter Genitourinary 0.988 0.947 – 1.03 0.567 2382 23863 exclusion phecode
594.8 Renal colic Genitourinary 0.984 0.94 – 1.03 0.487 2038 20377 exclusion phecode
595 Hydronephrosis Genitourinary 0.95 0.906 – 0.997 0.036 1876 19274 exclusion phecode
596 Other disorders of bladder Genitourinary 0.995 0.974 – 1.02 0.64 9653 97108 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.01 0.961 – 1.05 0.787 1944 19536 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 0.976 0.927 – 1.03 0.346 1645 16484 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.977 0.945 – 1.01 0.18 3883 38897 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.979 0.944 – 1.02 0.25 3297 32931 exclusion phecode
597.2 Urinary complications NEC Genitourinary 0.965 0.765 – 1.22 0.762 77 769 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 0.975 0.942 – 1.01 0.16 3497 35079 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.988 0.877 – 1.11 0.847 299 3016 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.992 – 1.02 0.39 18236 183233 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.934 0.798 – 1.09 0.392 165 1658 exclusion phecode
599.2 Retention of urine Genitourinary 1 0.975 – 1.03 0.984 6623 66660 exclusion phecode
599.3 Dysuria Genitourinary 1.02 0.957 – 1.08 0.59 1179 11899 exclusion phecode
599.4 Urinary incontinence Genitourinary 1.01 0.988 – 1.03 0.38 8672 87039 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.01 0.977 – 1.04 0.566 3977 39892 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.02 0.831 – 1.25 0.843 103 1054 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 0.875 0.68 – 1.13 0.302 62 618 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1 0.958 – 1.05 0.868 1896 19044 exclusion phecode
600 Hyperplasia of prostate Genitourinary 1 0.984 – 1.02 0.681 10951 87198 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 1.02 0.972 – 1.06 0.466 2058 20679 exclusion phecode
601.1 Prostatitis Genitourinary 1.02 0.969 – 1.08 0.436 1548 15543 exclusion phecode
601.11 Acute prostatitis Genitourinary 1.03 0.902 – 1.17 0.669 232 2336 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1.05 0.985 – 1.13 0.127 900 9021 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.922 0.702 – 1.21 0.557 59 582 exclusion phecode
601.4 Balanoposthitis Genitourinary 0.994 0.878 – 1.12 0.918 282 2843 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.07 0.956 – 1.21 0.23 300 2993 exclusion phecode
602 Other disorders of prostate Genitourinary 1.02 0.961 – 1.07 0.577 1331 13308 exclusion phecode
603 Other disorders of testis Genitourinary 0.97 0.927 – 1.01 0.177 2120 21358 exclusion phecode
603.1 Hydrocele Genitourinary 0.959 0.905 – 1.02 0.149 1322 13304 exclusion phecode
604 Disorders of penis Genitourinary 1.02 0.985 – 1.06 0.257 3247 32545 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.02 0.984 – 1.06 0.251 2693 26978 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 1.02 0.906 – 1.16 0.703 272 2782 exclusion phecode
608 Other disorders of male genital organs Genitourinary 1.01 0.968 – 1.05 0.75 2794 28044 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.04 0.904 – 1.2 0.581 212 2116 exclusion phecode
609.1 Infertility, male Genitourinary 0.888 0.675 – 1.17 0.397 62 637 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 1.1 0.939 – 1.29 0.238 168 1681 exclusion phecode
610 Benign mammary dysplasias Genitourinary 1.01 0.97 – 1.05 0.606 2463 24699 exclusion phecode
610.1 Cystic mastopathy Genitourinary 1 0.937 – 1.07 0.935 920 9213 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 0.985 0.873 – 1.11 0.805 300 3041 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 1.13 1.01 – 1.27 0.0391 300 2997 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 1 0.949 – 1.06 0.915 1380 13804 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.01 0.934 – 1.09 0.812 694 6916 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.99 0.94 – 1.04 0.699 1556 15668 exclusion phecode
611.1 Abnormal mammogram Genitourinary 1.19 0.909 – 1.56 0.206 55 566 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.992 0.941 – 1.05 0.77 1506 15155 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.04 0.975 – 1.12 0.213 884 8832 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.04 0.97 – 1.12 0.265 846 8452 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 1.09 0.865 – 1.38 0.454 72 716 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.967 0.918 – 1.02 0.192 1638 16439 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 0.929 0.86 – 1 0.0635 715 7178 exclusion phecode
613.5 Mastodynia Genitourinary 1.13 0.906 – 1.4 0.283 74 763 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.953 0.881 – 1.03 0.229 697 6984 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1.01 0.902 – 1.13 0.846 323 3264 exclusion phecode
613.9 Breast disorder NOS Genitourinary 1.11 0.962 – 1.28 0.154 206 2060 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.01 0.98 – 1.04 0.604 5686 56899 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1 0.96 – 1.04 0.977 2527 25273 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.04 0.965 – 1.11 0.328 829 8270 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.12 0.872 – 1.43 0.377 61 606 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.01 0.911 – 1.11 0.889 422 4208 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.11 1 – 1.24 0.0473 350 3494 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.04 0.918 – 1.17 0.551 276 2765 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.997 0.957 – 1.04 0.881 2589 25916 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.02 0.962 – 1.08 0.531 1309 13146 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.05 0.949 – 1.16 0.363 427 4256 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.966 0.895 – 1.04 0.364 752 7545 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.976 0.86 – 1.11 0.71 272 2726 exclusion phecode
615 Endometriosis Genitourinary 0.976 0.945 – 1.01 0.136 4018 40159 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.02 0.907 – 1.15 0.743 304 3024 exclusion phecode
618 Genital prolapse Genitourinary 0.996 0.977 – 1.02 0.68 11633 116295 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.989 0.966 – 1.01 0.372 7357 73570 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.01 0.981 – 1.04 0.55 5368 53663 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.03 0.945 – 1.13 0.475 511 5091 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.989 0.914 – 1.07 0.773 680 6753 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1.01 0.992 – 1.04 0.226 8682 86908 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.997 0.924 – 1.07 0.929 726 7258 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 1.03 0.994 – 1.07 0.099 3307 33130 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.998 0.961 – 1.04 0.934 2845 28484 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.999 0.952 – 1.05 0.961 1758 17577 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.986 0.932 – 1.04 0.629 1344 13434 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 0.859 0.664 – 1.11 0.245 72 717 exclusion phecode
621 Endometrial hyperplasia Genitourinary 1.05 0.989 – 1.12 0.107 1125 11255 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.995 0.976 – 1.02 0.658 10428 104334 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.99 0.968 – 1.01 0.41 7820 78241 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 1.01 0.977 – 1.05 0.521 3424 34222 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 0.957 0.903 – 1.01 0.132 1262 12645 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.986 0.917 – 1.06 0.698 794 7921 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.964 0.843 – 1.1 0.591 237 2353 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 0.976 0.885 – 1.08 0.63 438 4378 exclusion phecode
624.9 stress incontinence, female Genitourinary 1.03 1 – 1.06 0.0349 5829 58381 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.01 0.975 – 1.05 0.501 2861 28653 exclusion phecode
625.1 Dyspareunia Genitourinary 0.99 0.933 – 1.05 0.746 1183 11860 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.986 0.97 – 1 0.102 16109 114618 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.98 0.963 – 0.998 0.0254 14062 109541 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.892 0.735 – 1.08 0.248 107 1096 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 0.991 0.97 – 1.01 0.397 9690 91429 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 1.03 0.98 – 1.07 0.272 1977 19769 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.96 0.929 – 0.993 0.0175 3786 37906 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.964 0.917 – 1.01 0.143 1777 17710 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.984 0.837 – 1.16 0.845 159 1585 exclusion phecode
626.8 Infertility, female Genitourinary 1.01 0.958 – 1.07 0.658 1357 13581 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 1 0.98 – 1.02 0.973 10321 103433 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 1 0.981 – 1.02 0.796 8978 89973 exclusion phecode
627.2 Symptomatic menopause Genitourinary 1.16 0.996 – 1.35 0.0564 183 1816 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.97 0.912 – 1.03 0.349 1100 11047 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1.1 0.982 – 1.23 0.0989 308 3082 exclusion phecode
628 Ovarian cyst Genitourinary 1 0.973 – 1.03 0.873 4732 47311 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.995 0.966 – 1.02 0.726 5208 36331 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.02 0.958 – 1.08 0.567 1136 11271 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.02 0.911 – 1.15 0.716 331 3298 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.982 0.937 – 1.03 0.44 1972 17333 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.973 0.907 – 1.04 0.443 865 8590 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.995 0.939 – 1.05 0.866 1269 12277 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.01 0.965 – 1.05 0.745 2345 19923 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.982 0.904 – 1.07 0.674 617 6128 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.02 0.959 – 1.09 0.516 1082 10736 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 0.986 0.777 – 1.25 0.906 70 699 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.01 0.949 – 1.07 0.775 1110 11045 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.04 0.925 – 1.17 0.513 307 3050 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.05 0.912 – 1.21 0.506 215 2143 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.972 0.825 – 1.14 0.731 153 1521 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.977 0.922 – 1.04 0.433 1248 12425 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1 0.958 – 1.05 0.981 2226 20796 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1 0.788 – 1.28 0.968 68 678 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.917 0.81 – 1.04 0.171 274 2740 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.872 0.721 – 1.05 0.156 112 1127 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.02 0.884 – 1.19 0.754 193 1918 exclusion phecode
650 Normal delivery Pregnancy Complications 1.03 0.985 – 1.08 0.178 1916 18937 exclusion phecode
651 Multiple gestation Pregnancy Complications 0.988 0.885 – 1.1 0.828 346 3448 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.988 0.94 – 1.04 0.646 1715 16484 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.98 0.928 – 1.04 0.482 1397 13611 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.12 0.893 – 1.41 0.328 74 735 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.985 0.954 – 1.02 0.371 4296 29391 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.998 0.824 – 1.21 0.982 109 1078 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.984 0.941 – 1.03 0.471 2261 18363 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.964 0.881 – 1.05 0.418 532 5301 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.986 0.957 – 1.02 0.35 5303 29407 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.998 0.957 – 1.04 0.91 2547 21127 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.928 0.791 – 1.09 0.361 163 1623 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.1 0.969 – 1.24 0.145 262 2602 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.967 0.747 – 1.25 0.797 63 621 exclusion phecode
679 Complications of in utero procedures Dermatologic 1.07 0.803 – 1.42 0.652 53 530 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 0.983 0.959 – 1.01 0.181 7032 71784 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.1 1.01 – 1.2 0.031 549 5616 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.07 0.981 – 1.17 0.123 504 5182 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.973 0.946 – 1 0.0612 5363 54688 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.975 0.948 – 1 0.0752 5369 54748 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.973 0.946 – 1 0.056 5326 54316 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 0.961 0.882 – 1.05 0.373 581 5949 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 0.986 0.931 – 1.04 0.615 1308 13346 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 0.981 0.939 – 1.02 0.382 2246 22820 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.02 0.937 – 1.11 0.653 576 5807 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 0.942 0.843 – 1.05 0.286 359 3599 exclusion phecode
687 Symptoms affecting skin Dermatologic 1.05 0.964 – 1.15 0.26 535 5470 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.985 0.94 – 1.03 0.507 2016 21364 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.04 0.92 – 1.17 0.552 280 2827 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.899 0.739 – 1.09 0.286 103 1066 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 0.981 0.944 – 1.02 0.344 2842 28718 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.01 0.98 – 1.03 0.63 5654 57177 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.748 0.582 – 0.962 0.0234 71 705 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.703 0.523 – 0.946 0.0201 53 526 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.921 0.76 – 1.12 0.398 112 1191 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 1.01 0.942 – 1.07 0.862 972 9814 exclusion phecode
694.1 Vitiligo Dermatologic 1.02 0.79 – 1.33 0.863 59 596 exclusion phecode
694.2 Other dyschromia Dermatologic 1.01 0.935 – 1.08 0.871 773 7787 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 0.976 0.806 – 1.18 0.801 113 1162 exclusion phecode
695 Erythematous conditions Dermatologic 0.999 0.958 – 1.04 0.97 2329 23687 exclusion phecode
695.1 Toxic erythema Dermatologic 1.01 0.828 – 1.22 0.944 107 1079 exclusion phecode
695.2 Bullous dermatoses Dermatologic 0.928 0.778 – 1.11 0.411 133 1358 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 0.703 0.524 – 0.942 0.0185 55 565 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.15 0.903 – 1.46 0.26 72 723 exclusion phecode
695.3 Rosacea Dermatologic 0.969 0.862 – 1.09 0.598 306 3078 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 0.921 0.83 – 1.02 0.123 403 4095 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.861 0.714 – 1.04 0.117 126 1294 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 0.946 0.844 – 1.06 0.336 333 3388 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 1.07 0.996 – 1.15 0.0631 769 7720 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 0.978 0.858 – 1.12 0.742 224 2350 exclusion phecode
695.81 Erythema nodosum Dermatologic 1.1 0.878 – 1.37 0.412 73 754 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 0.96 0.871 – 1.06 0.41 447 4648 exclusion phecode
696 Psoriasis and related disorders Dermatologic 1.04 1 – 1.09 0.0476 2220 22379 exclusion phecode
696.4 Psoriasis Dermatologic 1.04 0.999 – 1.09 0.0581 2170 21841 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 1.04 0.987 – 1.09 0.147 1657 16699 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 1.06 0.982 – 1.15 0.134 696 7012 exclusion phecode
697 Sarcoidosis Dermatologic 0.825 0.752 – 0.906 5.08e-05 528 5334 exclusion phecode
698 Pruritus and related conditions Dermatologic 1.03 0.959 – 1.11 0.387 770 7782 exclusion phecode
700 Corns and callosities Dermatologic 0.886 0.786 – 1 0.0496 289 2889 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.01 0.979 – 1.04 0.572 4615 46391 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.92 0.73 – 1.16 0.484 86 864 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1 0.963 – 1.05 0.829 2323 23349 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 1.13 0.888 – 1.45 0.313 59 608 exclusion phecode
701.4 Keloid scar Dermatologic 0.981 0.853 – 1.13 0.785 214 2149 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 0.97 0.879 – 1.07 0.54 449 4542 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.03 0.845 – 1.26 0.769 100 1017 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.03 1 – 1.06 0.0237 5394 54233 exclusion phecode
702.1 Actinic keratosis Dermatologic 1.04 0.999 – 1.08 0.0556 2546 25689 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 1.03 0.996 – 1.07 0.0836 3049 30574 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.02 0.915 – 1.13 0.732 349 3509 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.968 0.905 – 1.04 0.34 955 9610 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.968 0.941 – 0.996 0.0274 5236 52437 exclusion phecode
704.1 Alopecia Dermatologic 1.06 0.882 – 1.27 0.544 123 1264 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.22 0.972 – 1.52 0.0865 76 753 exclusion phecode
705 Disorders of sweat glands Dermatologic 1.01 0.88 – 1.15 0.937 226 2276 exclusion phecode
705.3 Hidradenitis Dermatologic 0.906 0.78 – 1.05 0.201 185 1862 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.01 0.931 – 1.1 0.753 561 5881 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 0.972 0.95 – 0.994 0.0144 8269 82719 exclusion phecode
706.1 Acne Dermatologic 1.19 0.958 – 1.47 0.117 76 774 exclusion phecode
706.2 Sebaceous cyst Dermatologic 0.977 0.955 – 0.998 0.0362 8737 87379 exclusion phecode
707 Chronic ulcer of skin Dermatologic 0.992 0.946 – 1.04 0.728 1875 19501 exclusion phecode
707.1 Decubitus ulcer Dermatologic 0.973 0.908 – 1.04 0.441 862 9018 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.995 0.961 – 1.03 0.782 3388 34139 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.03 0.935 – 1.12 0.595 490 5049 exclusion phecode
709.3 Systemic sclerosis Dermatologic 1.09 0.932 – 1.28 0.278 170 1746 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.762 0.584 – 0.995 0.0458 64 646 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.993 0.955 – 1.03 0.741 2691 26995 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.947 0.869 – 1.03 0.216 586 5990 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 0.963 0.88 – 1.05 0.41 540 5528 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.912 0.785 – 1.06 0.231 188 1931 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.938 0.843 – 1.04 0.239 388 3964 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 0.988 0.893 – 1.09 0.812 414 4203 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 0.965 0.861 – 1.08 0.549 321 3277 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 0.883 0.709 – 1.1 0.269 80 803 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.926 0.78 – 1.1 0.382 144 1494 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 0.936 0.728 – 1.2 0.607 63 668 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.13 1.1 – 1.17 1.1e-16 4748 48046 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.14 1.11 – 1.18 1.07e-17 4298 43475 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.08 1.03 – 1.14 0.00175 1643 16486 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.23 1.02 – 1.49 0.0305 112 1123 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.24 1.14 – 1.34 3.38e-07 607 6127 exclusion phecode
716 Other arthropathies Musculoskeletal 1.01 1 – 1.02 0.0464 37168 263914 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1 0.971 – 1.04 0.783 3470 34855 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 1 0.988 – 1.02 0.574 15421 154405 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.01 1 – 1.02 0.0288 35648 260860 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.05 0.986 – 1.11 0.13 1131 11394 exclusion phecode
720 Spinal stenosis Musculoskeletal 1 0.97 – 1.04 0.861 3674 36848 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 0.998 0.975 – 1.02 0.842 7744 77850 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.991 0.963 – 1.02 0.555 4990 50147 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.905 0.78 – 1.05 0.187 188 1888 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 1.05 0.937 – 1.17 0.422 340 3495 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 0.986 0.965 – 1.01 0.198 8892 89366 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.982 0.897 – 1.07 0.691 507 5091 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.996 0.958 – 1.04 0.833 2795 28151 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.1 0.866 – 1.4 0.429 67 665 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.973 0.943 – 1 0.0816 4377 43872 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 0.993 0.908 – 1.09 0.884 515 5147 exclusion phecode
723.1 Torticollis Musculoskeletal 0.96 0.786 – 1.17 0.694 107 1060 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1 0.957 – 1.05 0.95 2027 20410 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1.05 0.946 – 1.16 0.37 400 4012 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 1.04 0.943 – 1.15 0.414 403 4042 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.19 0.936 – 1.51 0.156 62 627 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 0.982 0.932 – 1.03 0.476 1592 16051 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1 0.983 – 1.02 0.985 14545 145829 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.999 0.978 – 1.02 0.925 9518 95310 exclusion phecode
726.2 Synoviopathy Musculoskeletal 1.07 0.956 – 1.2 0.235 333 3323 exclusion phecode
726.3 Bursitis Musculoskeletal 0.999 0.932 – 1.07 0.984 844 8525 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1 0.978 – 1.03 0.872 7287 72942 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.04 0.995 – 1.08 0.0846 2722 27261 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.919 0.745 – 1.13 0.428 102 1021 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1 0.965 – 1.04 0.939 3094 30907 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.962 0.882 – 1.05 0.378 580 5819 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.973 0.873 – 1.08 0.625 350 3505 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.953 0.799 – 1.14 0.589 143 1420 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.02 0.982 – 1.05 0.354 3660 36498 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.1 0.996 – 1.22 0.0597 412 4104 exclusion phecode
728.7 Fasciitis Musculoskeletal 1.02 0.985 – 1.05 0.29 3787 37759 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.02 0.982 – 1.05 0.345 3462 34510 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1 0.973 – 1.03 0.974 5924 59934 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.02 0.956 – 1.09 0.539 1000 10022 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.998 0.816 – 1.22 0.983 101 1005 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.07 0.944 – 1.2 0.303 272 2745 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.05 0.925 – 1.19 0.448 257 2599 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.965 0.876 – 1.06 0.462 466 4653 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.944 0.818 – 1.09 0.428 206 2063 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.986 0.755 – 1.29 0.915 57 565 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.999 0.951 – 1.05 0.96 1755 17716 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.04 0.926 – 1.17 0.5 310 3102 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.943 0.862 – 1.03 0.202 523 5361 exclusion phecode
733.6 Costochondritis Musculoskeletal 1.05 0.876 – 1.25 0.616 126 1270 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.969 0.914 – 1.03 0.28 1222 12259 exclusion phecode
733.9 Chondromalacia Musculoskeletal 0.965 0.799 – 1.16 0.707 121 1200 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1.04 1.01 – 1.06 0.0012 9558 95546 exclusion phecode
735.1 Flat foot Musculoskeletal 1.01 0.871 – 1.17 0.88 188 1901 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 1.03 1 – 1.06 0.0267 5042 50390 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.03 0.984 – 1.08 0.201 1919 19202 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.985 0.935 – 1.04 0.576 1544 15427 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.04 1.01 – 1.07 0.00278 6619 66100 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 0.972 0.923 – 1.02 0.268 1612 16189 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 0.944 0.829 – 1.08 0.387 246 2463 exclusion phecode
737 Curvature of spine Musculoskeletal 0.99 0.931 – 1.05 0.756 1116 11236 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.984 0.924 – 1.05 0.62 1049 10573 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1 0.955 – 1.05 0.981 1864 18935 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.01 0.957 – 1.06 0.742 1498 15036 exclusion phecode
739 Contracture of joint Musculoskeletal 0.975 0.889 – 1.07 0.6 485 4854 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.01 0.998 – 1.02 0.0985 27493 230155 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.01 0.989 – 1.02 0.525 17284 168317 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1 0.981 – 1.02 0.816 8909 89150 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.987 0.884 – 1.1 0.822 343 3460 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.02 0.935 – 1.1 0.706 594 5939 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.02 0.996 – 1.03 0.114 12169 122014 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.03 0.991 – 1.06 0.153 3528 35442 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 1.05 0.859 – 1.28 0.637 101 1014 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 0.961 0.883 – 1.05 0.35 608 6113 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.884 0.745 – 1.05 0.158 152 1535 exclusion phecode
741.4 Joint effusions Musculoskeletal 1.02 0.963 – 1.07 0.559 1402 14094 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.14 0.943 – 1.37 0.179 110 1096 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.908 0.69 – 1.2 0.491 53 535 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.02 0.979 – 1.06 0.364 2829 28297 exclusion phecode
742.1 Loose body in joint Musculoskeletal 1.05 0.941 – 1.17 0.379 331 3318 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.04 0.85 – 1.27 0.702 94 955 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.05 0.958 – 1.15 0.296 496 4970 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 1 0.956 – 1.05 0.971 1986 19836 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1 0.979 – 1.03 0.857 7424 75289 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1 0.979 – 1.03 0.744 6298 63738 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.01 0.979 – 1.03 0.651 5465 55291 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1.02 0.935 – 1.12 0.637 520 5249 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 0.958 0.873 – 1.05 0.366 486 5148 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.01 0.935 – 1.08 0.888 797 8098 exclusion phecode
745 Pain in joint Musculoskeletal 1 0.982 – 1.03 0.682 7889 79341 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.989 0.951 – 1.03 0.565 2751 27865 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.99 0.951 – 1.03 0.622 2579 26138 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.936 0.858 – 1.02 0.13 578 5808 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.01 0.885 – 1.16 0.868 233 2343 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.994 0.947 – 1.04 0.792 1776 18050 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.948 0.805 – 1.12 0.527 165 1669 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.23 0.926 – 1.64 0.152 51 507 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.947 0.84 – 1.07 0.372 300 3004 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 1.01 0.928 – 1.09 0.901 680 6821 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.983 0.876 – 1.1 0.774 324 3233 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.961 0.826 – 1.12 0.604 188 1890 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.01 0.904 – 1.12 0.887 352 3556 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.04 0.908 – 1.19 0.574 223 2246 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.952 0.787 – 1.15 0.612 115 1171 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.01 0.958 – 1.06 0.725 1515 15210 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.02 0.947 – 1.11 0.562 691 6905 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.979 0.89 – 1.08 0.669 454 4534 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.04 0.908 – 1.2 0.555 220 2202 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.997 0.929 – 1.07 0.945 827 8331 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 1.04 0.946 – 1.15 0.399 420 4209 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.935 0.834 – 1.05 0.252 328 3331 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.956 0.854 – 1.07 0.429 327 3289 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 0.962 0.846 – 1.09 0.557 253 2546 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.933 0.81 – 1.07 0.332 208 2098 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.07 0.854 – 1.34 0.556 77 774 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.09 0.915 – 1.31 0.327 127 1263 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.32 1.06 – 1.65 0.0121 76 757 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.18 0.974 – 1.42 0.0917 109 1098 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.972 0.879 – 1.07 0.573 422 4249 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.971 0.843 – 1.12 0.683 206 2075 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.04 0.889 – 1.23 0.6 159 1609 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.01 0.824 – 1.23 0.959 106 1065 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.925 0.849 – 1.01 0.0767 578 5843 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.953 0.763 – 1.19 0.673 81 807 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.927 0.84 – 1.02 0.137 427 4336 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.09 0.921 – 1.28 0.327 144 1701 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.2 0.931 – 1.55 0.158 58 827 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.09 0.95 – 1.25 0.221 214 2148 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.977 0.786 – 1.21 0.834 96 955 exclusion phecode
760 Back pain Symptoms 0.988 0.969 – 1.01 0.239 10977 110746 exclusion phecode
761 Cervicalgia Symptoms 1 0.954 – 1.05 0.957 1774 17801 exclusion phecode
764 Sciatica Symptoms 0.958 0.918 – 1 0.0523 2356 23598 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.01 0.955 – 1.08 0.646 1163 11666 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1 0.922 – 1.09 0.958 622 6275 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.02 0.952 – 1.1 0.551 851 8636 exclusion phecode
771.1 Swelling of limb Symptoms 0.999 0.969 – 1.03 0.969 4536 46031 exclusion phecode
772 Symptoms of the muscles Symptoms 0.978 0.902 – 1.06 0.58 647 6547 exclusion phecode
773 Pain in limb Symptoms 0.991 0.966 – 1.02 0.505 6149 61851 exclusion phecode
780 Hypothermia/Chills Symptoms 0.839 0.712 – 0.989 0.0364 168 1706 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.998 0.952 – 1.05 0.94 1837 18600 exclusion phecode
782.3 Edema Symptoms 0.968 0.919 – 1.02 0.22 1545 16345 exclusion phecode
782.6 Pallor and flushing Symptoms 1.02 0.873 – 1.18 0.835 173 1739 exclusion phecode
783 Fever of unknown origin Symptoms 1 0.968 – 1.04 0.937 3596 38915 exclusion phecode
785 Abdominal pain Symptoms 0.999 0.989 – 1.01 0.842 39673 300151 exclusion phecode
788 Syncope and collapse Symptoms 0.997 0.976 – 1.02 0.821 8956 90188 exclusion phecode
789 Nausea and vomiting Symptoms 1 0.984 – 1.02 0.775 11288 115167 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1 0.848 – 1.19 0.959 147 1495 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 0.88 0.695 – 1.11 0.289 76 835 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 0.994 0.969 – 1.02 0.658 6219 63172 exclusion phecode
791 Gangrene Symptoms 0.997 0.912 – 1.09 0.947 537 5459 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1.09 0.894 – 1.33 0.391 96 961 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.935 0.781 – 1.12 0.467 128 1332 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 0.994 0.912 – 1.08 0.895 551 5612 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.01 0.839 – 1.22 0.912 119 1195 exclusion phecode
797 Shock Symptoms 1.03 0.871 – 1.21 0.753 151 1551 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.07 0.875 – 1.31 0.511 99 1014 exclusion phecode
798 Malaise and fatigue Symptoms 0.975 0.941 – 1.01 0.17 3294 33907 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 0.928 0.852 – 1.01 0.0864 588 5891 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 0.984 0.96 – 1.01 0.204 6971 69933 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.02 0.97 – 1.07 0.467 1788 18033 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.934 0.797 – 1.09 0.397 168 1681 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.985 0.942 – 1.03 0.498 2146 21461 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 1.04 0.97 – 1.12 0.251 760 7617 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.995 0.952 – 1.04 0.815 2193 21926 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1 0.957 – 1.05 0.868 1826 18247 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.09 1.01 – 1.17 0.0336 710 7145 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 1.02 0.996 – 1.04 0.108 8226 82433 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 0.98 0.932 – 1.03 0.427 1679 16794 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.03 1 – 1.06 0.0406 5177 51887 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.03 0.974 – 1.08 0.338 1502 15088 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.987 0.953 – 1.02 0.484 3315 33185 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.955 0.903 – 1.01 0.11 1335 13486 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 0.96 0.891 – 1.03 0.277 767 7700 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 1 0.947 – 1.06 0.929 1285 12920 exclusion phecode
817 Concussion Injuries & Poisonings 1.08 0.947 – 1.23 0.256 242 2411 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.956 0.872 – 1.05 0.332 519 5174 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.983 0.946 – 1.02 0.37 2940 29430 exclusion phecode
823 Torus fracture Injuries & Poisonings 0.968 0.921 – 1.02 0.214 1662 16625 exclusion phecode
830 Dislocation Injuries & Poisonings 0.985 0.941 – 1.03 0.503 2076 20753 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.994 0.978 – 1.01 0.485 15145 151370 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.988 0.903 – 1.08 0.787 524 5241 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.935 0.848 – 1.03 0.178 467 4665 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.998 0.97 – 1.03 0.9 5188 52337 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.08 0.916 – 1.28 0.354 152 1560 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.02 0.929 – 1.12 0.686 488 4978 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.958 0.912 – 1.01 0.088 1763 18124 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.949 0.895 – 1.01 0.0819 1223 12326 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.03 0.995 – 1.07 0.088 3127 31420 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1 0.968 – 1.04 0.844 3224 32390 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.989 0.955 – 1.02 0.521 3478 34866 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.02 0.9 – 1.15 0.787 272 2702 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 0.889 0.768 – 1.03 0.116 196 1937 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.998 0.961 – 1.04 0.933 2881 28912 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.948 0.824 – 1.09 0.461 219 2188 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.979 0.763 – 1.26 0.866 68 672 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 0.979 0.948 – 1.01 0.208 4028 40409 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.14 0.885 – 1.48 0.304 52 526 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.26 1.03 – 1.54 0.0238 90 894 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.957 0.823 – 1.11 0.571 177 1768 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 0.938 0.853 – 1.03 0.189 473 4700 exclusion phecode
873 Broken tooth Injuries & Poisonings 0.991 0.861 – 1.14 0.897 223 2272 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.08 0.924 – 1.25 0.346 169 1699 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 0.962 0.817 – 1.13 0.643 156 1560 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 0.968 0.914 – 1.02 0.258 1307 13076 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1 0.97 – 1.03 0.954 4211 42420 exclusion phecode
916 Contusion Injuries & Poisonings 0.976 0.925 – 1.03 0.381 1438 14415 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 1.09 0.942 – 1.27 0.236 179 1800 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.05 0.945 – 1.16 0.373 385 3874 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 1.02 0.9 – 1.16 0.727 250 2518 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.96 0.916 – 1 0.0784 2035 20835 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.93 0.808 – 1.07 0.309 220 2235 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.04 0.841 – 1.28 0.728 91 1031 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.01 0.928 – 1.1 0.783 544 5483 exclusion phecode
947 Urticaria Injuries & Poisonings 1 0.9 – 1.11 0.986 362 3688 exclusion phecode
949 Allergies, other Injuries & Poisonings 0.984 0.886 – 1.09 0.755 391 3967 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.998 0.904 – 1.1 0.968 416 4206 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.02 0.896 – 1.16 0.784 268 2686 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.05 0.954 – 1.15 0.331 485 4894 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.21 0.91 – 1.6 0.192 54 551 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.29 1.02 – 1.62 0.032 73 737 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.981 0.966 – 0.996 0.0158 17847 180237 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.981 0.965 – 0.998 0.0261 15635 157828 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1 0.908 – 1.11 0.927 410 4177 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.01 0.938 – 1.08 0.856 847 8670 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.01 0.905 – 1.13 0.853 350 3686 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.04 0.929 – 1.16 0.513 343 3620 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.929 0.809 – 1.07 0.296 214 2221 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.991 0.878 – 1.12 0.879 276 2818 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.973 0.861 – 1.1 0.657 270 2757 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.991 0.965 – 1.02 0.505 6021 60584 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.01 0.95 – 1.07 0.751 1132 11384 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.993 0.904 – 1.09 0.886 475 4747 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.923 0.832 – 1.02 0.134 399 4020 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.05 0.958 – 1.15 0.301 510 5102 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.03 0.947 – 1.12 0.485 573 5812 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.02 0.973 – 1.07 0.417 1938 19430 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.916 0.788 – 1.07 0.257 189 1899 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.873 0.768 – 0.993 0.0388 269 2701 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.727 0.577 – 0.917 0.00704 84 845 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 0.975 0.802 – 1.18 0.796 107 1077 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.02 0.828 – 1.26 0.857 99 1014 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.02 0.789 – 1.32 0.883 63 638 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.05 0.799 – 1.37 0.745 57 577 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.92 0.802 – 1.06 0.235 224 2316 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 0.998 0.923 – 1.08 0.956 685 6927 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.926 0.799 – 1.07 0.308 200 1991 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.15 0.893 – 1.47 0.284 62 615 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.12 0.912 – 1.36 0.287 104 1044 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 1.03 0.848 – 1.24 0.786 111 1119 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.975 0.79 – 1.2 0.813 89 884 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 0.984 0.947 – 1.02 0.395 2892 31013 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 0.952 0.914 – 0.991 0.0156 2633 30112 exclusion phecode
994.2 Sepsis Injuries & Poisonings 0.952 0.914 – 0.991 0.0156 2633 30112 exclusion phecode
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