Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Age at menarche UK Biobank (UKB) PheWAS analysis

Age at menarche — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID exprsweb-age-at-menarche-ieu-a-1095-dbslmm-ukb-20211120Legacy DBSLMMDBSLMMLarge GWAS

Evaluation cohort: UK Biobank (UKB).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: study-defined normal-range subset.

For this ExPRS, the exclusion sensitivity scan keeps only the study-defined normal-range subset for Age at menarche before rerunning the PheWAS. The preserved release does not include numeric bounds for this trait. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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115 rows visible 16 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 0.976 0.955 – 0.998 0.0293 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 0.999 0.96 – 1.04 0.943 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.961 0.887 – 1.04 0.336 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 0.94 0.876 – 1.01 0.0849 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 0.806 0.615 – 1.06 0.117 55 550 all phecode
010 Tuberculosis Infectious Diseases 1 0.856 – 1.17 0.973 166 1659 all phecode
038 Septicemia Infectious Diseases 0.979 0.948 – 1.01 0.196 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 0.945 0.881 – 1.01 0.118 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 0.997 0.912 – 1.09 0.956 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 0.987 0.969 – 1.01 0.179 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 0.988 0.952 – 1.02 0.517 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 0.961 0.913 – 1.01 0.121 1641 16433 all phecode
041.4 E. coli Infectious Diseases 0.993 0.954 – 1.03 0.716 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 0.95 0.86 – 1.05 0.314 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.89 0.721 – 1.1 0.282 95 949 all phecode
054 Herpes simplex Infectious Diseases 0.918 0.798 – 1.06 0.234 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 1.01 0.924 – 1.09 0.893 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 0.986 0.771 – 1.26 0.912 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 1 0.835 – 1.2 0.985 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.06 0.937 – 1.21 0.336 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 0.939 0.832 – 1.06 0.311 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 0.999 0.904 – 1.1 0.988 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.992 0.841 – 1.17 0.921 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.955 0.792 – 1.15 0.629 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 0.942 0.883 – 1 0.0661 1004 10036 all phecode
079 Viral infection Infectious Diseases 0.988 0.95 – 1.03 0.547 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 1.04 0.805 – 1.33 0.788 64 640 all phecode
080 Postoperative infection Infectious Diseases 0.983 0.953 – 1.01 0.263 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 0.993 0.953 – 1.03 0.73 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.23 0.963 – 1.56 0.0982 71 709 all phecode
1000 Burns Injuries & Poisonings 1.07 0.984 – 1.17 0.111 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 0.926 0.873 – 0.983 0.0111 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.02 0.994 – 1.05 0.123 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.15 1.02 – 1.3 0.0214 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 0.967 0.916 – 1.02 0.221 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 0.992 0.87 – 1.13 0.899 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 1.02 0.897 – 1.16 0.753 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1 0.938 – 1.07 0.989 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 1.01 0.991 – 1.04 0.242 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 0.962 0.937 – 0.988 0.0046 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.01 0.99 – 1.03 0.302 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 1.15 0.944 – 1.4 0.166 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 0.91 0.81 – 1.02 0.113 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.96 0.75 – 1.23 0.747 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 0.998 0.967 – 1.03 0.882 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 0.993 0.977 – 1.01 0.37 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.07 0.943 – 1.21 0.308 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 1.06 0.938 – 1.2 0.347 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.03 0.811 – 1.3 0.826 74 756 all phecode
110.12 Althete's foot Infectious Diseases 1.08 0.915 – 1.28 0.354 141 1410 all phecode
112 Candidiasis Infectious Diseases 0.977 0.934 – 1.02 0.298 2126 21275 all phecode
117 Mycoses Infectious Diseases 1 0.889 – 1.13 0.953 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 0.965 0.825 – 1.13 0.658 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 1.09 0.868 – 1.38 0.451 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 0.958 0.76 – 1.21 0.72 69 689 all phecode
134 Helminthiases Infectious Diseases 0.909 0.759 – 1.09 0.302 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 0.934 0.766 – 1.14 0.499 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.994 0.862 – 1.15 0.94 205 2050 all phecode
145 Cancer of mouth Neoplasms 0.988 0.91 – 1.07 0.771 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 0.964 0.856 – 1.08 0.54 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.07 0.874 – 1.3 0.522 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.2 0.916 – 1.58 0.183 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.02 0.938 – 1.1 0.677 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 1.01 0.892 – 1.15 0.844 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 1.04 0.913 – 1.18 0.564 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 1.18 0.907 – 1.54 0.216 57 570 all phecode
150 Cancer of esophagus Neoplasms 0.946 0.878 – 1.02 0.145 762 7630 all phecode
151 Cancer of stomach Neoplasms 1 0.922 – 1.09 0.921 569 5696 all phecode
153 Colorectal cancer Neoplasms 1.02 0.986 – 1.05 0.289 4580 45799 all phecode
153.2 Colon cancer Neoplasms 1 0.966 – 1.04 0.916 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.02 0.972 – 1.06 0.471 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.968 0.873 – 1.07 0.538 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.07 0.912 – 1.27 0.391 158 1580 all phecode
157 Pancreatic cancer Neoplasms 1.04 0.962 – 1.13 0.316 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.942 0.884 – 1 0.065 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1 0.977 – 1.03 0.774 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.09 0.94 – 1.27 0.254 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.916 0.795 – 1.06 0.227 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.891 0.772 – 1.03 0.114 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 0.913 0.705 – 1.18 0.49 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 1.02 0.979 – 1.06 0.389 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.02 0.98 – 1.07 0.288 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.922 0.837 – 1.02 0.103 437 4364 all phecode
170.1 Bone cancer Neoplasms 0.893 0.746 – 1.07 0.221 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 0.94 0.842 – 1.05 0.278 331 3303 all phecode
172 Skin cancer Neoplasms 1 0.987 – 1.02 0.591 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.988 0.95 – 1.03 0.553 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 0.991 0.953 – 1.03 0.641 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1.01 0.993 – 1.03 0.209 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 0.985 0.909 – 1.07 0.701 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.983 0.844 – 1.14 0.826 181 1818 all phecode
174 Breast cancer Neoplasms 0.985 0.967 – 1 0.0986 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 0.983 0.965 – 1 0.0621 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.982 0.964 – 1 0.0621 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.991 0.819 – 1.2 0.93 115 1148 all phecode
175 Acquired absence of breast Neoplasms 1.01 0.972 – 1.06 0.53 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 1.01 0.97 – 1.06 0.561 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 1.1 0.967 – 1.25 0.148 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.01 0.969 – 1.06 0.554 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 1.04 0.979 – 1.1 0.218 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 0.996 0.942 – 1.05 0.899 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.01 0.944 – 1.08 0.802 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.999 0.934 – 1.07 0.984 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.01 0.901 – 1.14 0.823 305 3049 all phecode
185 Cancer of prostate Neoplasms 0.978 0.952 – 1 0.104 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 0.997 0.904 – 1.1 0.953 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.27 1 – 1.62 0.0503 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.946 0.837 – 1.07 0.375 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.12 0.923 – 1.36 0.252 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1 0.971 – 1.03 0.88 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.949 0.891 – 1.01 0.108 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.945 0.886 – 1.01 0.084 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.07 0.832 – 1.39 0.585 66 660 all phecode
189.2 Cancer of bladder Neoplasms 1.01 0.973 – 1.06 0.493 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.01 0.966 – 1.06 0.68 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.951 0.802 – 1.13 0.558 144 1439 all phecode
190 Cancer of eye Neoplasms 1.07 0.917 – 1.26 0.376 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.04 0.961 – 1.12 0.334 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1.04 0.95 – 1.13 0.42 566 5650 all phecode
191.11 Cancer of brain Neoplasms 1.05 0.955 – 1.14 0.332 525 5240 all phecode
193 Thyroid cancer Neoplasms 1.04 0.932 – 1.16 0.48 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 0.897 0.732 – 1.1 0.298 95 949 all phecode
195 Cancer, suspected or other Neoplasms 1 0.985 – 1.02 0.955 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 1 0.986 – 1.02 0.78 16267 159497 all phecode
197 Chemotherapy Neoplasms 0.994 0.98 – 1.01 0.386 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 1.01 0.985 – 1.03 0.601 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.998 0.971 – 1.03 0.895 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.01 0.968 – 1.06 0.619 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.04 0.989 – 1.1 0.122 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.01 0.975 – 1.06 0.484 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.07 1 – 1.15 0.0463 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.02 0.976 – 1.07 0.38 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.08 0.928 – 1.25 0.321 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.04 0.983 – 1.1 0.178 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 0.904 0.738 – 1.11 0.331 95 950 all phecode
200 Myeloproliferative disease Neoplasms 0.918 0.861 – 0.98 0.0104 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 0.87 0.784 – 0.965 0.00864 387 3867 all phecode
201 Hodgkin's disease Neoplasms 0.902 0.795 – 1.02 0.106 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1 0.958 – 1.04 0.997 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.01 0.967 – 1.07 0.549 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 0.961 0.863 – 1.07 0.474 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 1.04 0.954 – 1.13 0.37 581 5824 all phecode
204 Leukemia Neoplasms 1.02 0.968 – 1.07 0.49 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 1.06 0.977 – 1.16 0.153 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.2 0.913 – 1.57 0.194 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.05 0.959 – 1.15 0.285 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 0.998 0.908 – 1.1 0.975 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.998 0.89 – 1.12 0.977 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.96 0.814 – 1.13 0.631 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 1.01 0.926 – 1.1 0.814 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 0.985 0.97 – 0.999 0.0394 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.95 0.889 – 1.01 0.128 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.984 0.957 – 1.01 0.273 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.983 0.881 – 1.1 0.754 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.953 0.849 – 1.07 0.422 318 3187 all phecode
214 Lipoma Neoplasms 1.01 0.988 – 1.04 0.29 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.02 0.987 – 1.05 0.278 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.999 0.939 – 1.06 0.975 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 0.99 0.967 – 1.01 0.405 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.06 0.98 – 1.16 0.139 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.1 1.01 – 1.2 0.0299 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 0.996 0.976 – 1.02 0.727 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 0.993 0.973 – 1.01 0.478 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.05 0.944 – 1.17 0.36 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 1.02 0.964 – 1.07 0.543 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.911 0.794 – 1.05 0.183 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.982 0.834 – 1.16 0.826 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.12 0.956 – 1.31 0.162 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 1.2 1 – 1.43 0.0502 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.27 0.996 – 1.63 0.0539 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.12 1.04 – 1.2 0.00208 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.13 1.05 – 1.21 0.0015 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.06 0.813 – 1.38 0.667 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.04 0.915 – 1.18 0.55 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.951 0.887 – 1.02 0.154 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.953 0.822 – 1.1 0.516 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.933 0.84 – 1.04 0.201 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.974 0.866 – 1.09 0.654 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.973 0.924 – 1.02 0.288 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.971 0.931 – 1.01 0.177 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.04 0.96 – 1.14 0.311 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.04 0.977 – 1.11 0.216 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.06 0.965 – 1.17 0.218 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.01 0.931 – 1.09 0.854 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.981 0.935 – 1.03 0.424 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 0.957 0.869 – 1.05 0.379 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.14 0.918 – 1.43 0.231 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 0.975 0.822 – 1.16 0.771 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 0.964 0.947 – 0.98 2.01e-05 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.01 0.952 – 1.08 0.697 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.24 1.01 – 1.51 0.0389 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.961 0.945 – 0.978 7.82e-06 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 1.02 0.902 – 1.15 0.764 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.06 0.921 – 1.22 0.423 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.07 0.93 – 1.23 0.341 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 0.998 0.899 – 1.11 0.965 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 0.977 0.963 – 0.991 0.00172 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.971 0.934 – 1.01 0.147 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.02 0.898 – 1.17 0.732 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.929 0.734 – 1.17 0.538 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.92 0.838 – 1.01 0.0777 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 0.998 0.85 – 1.17 0.98 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.974 0.959 – 0.989 0.000646 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.21 0.997 – 1.47 0.0534 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.983 0.853 – 1.13 0.819 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.949 0.89 – 1.01 0.117 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 0.93 0.85 – 1.02 0.112 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 0.99 0.916 – 1.07 0.808 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.958 0.847 – 1.09 0.503 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.02 0.923 – 1.13 0.696 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.02 0.848 – 1.22 0.855 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.935 0.839 – 1.04 0.222 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.929 0.878 – 0.982 0.00982 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.02 0.95 – 1.09 0.645 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.97 0.906 – 1.04 0.393 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.968 0.9 – 1.04 0.385 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.932 0.787 – 1.1 0.415 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.944 0.873 – 1.02 0.144 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.02 0.876 – 1.18 0.837 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.923 0.749 – 1.14 0.454 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.823 0.725 – 0.935 0.00272 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.854 0.691 – 1.06 0.144 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.05 0.895 – 1.23 0.553 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.997 0.919 – 1.08 0.935 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.957 0.827 – 1.11 0.559 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.01 0.834 – 1.23 0.895 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.84 0.676 – 1.04 0.116 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.03 0.924 – 1.14 0.61 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.03 0.922 – 1.14 0.626 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 0.957 0.84 – 1.09 0.504 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.917 0.797 – 1.05 0.22 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 1.07 0.915 – 1.26 0.381 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.05 0.89 – 1.24 0.561 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.974 0.797 – 1.19 0.796 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 0.948 0.802 – 1.12 0.534 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.98 0.851 – 1.13 0.776 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 0.933 0.693 – 1.26 0.645 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 0.983 0.915 – 1.06 0.636 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.02 0.96 – 1.08 0.549 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.01 0.936 – 1.09 0.807 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.06 0.965 – 1.17 0.213 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.09 0.873 – 1.37 0.433 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.1 0.962 – 1.25 0.17 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 1 0.898 – 1.12 0.947 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.04 0.927 – 1.18 0.479 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.04 0.916 – 1.18 0.543 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1 0.862 – 1.16 0.992 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 0.89 0.732 – 1.08 0.242 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.21 0.941 – 1.54 0.139 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.997 0.849 – 1.17 0.968 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.953 0.802 – 1.13 0.587 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.983 0.972 – 0.994 0.00326 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.983 0.972 – 0.995 0.00361 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.982 0.971 – 0.994 0.00274 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.1 0.84 – 1.45 0.476 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.04 0.886 – 1.22 0.641 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.997 0.87 – 1.14 0.964 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.987 0.954 – 1.02 0.441 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 0.975 0.94 – 1.01 0.178 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.884 0.73 – 1.07 0.205 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.03 0.951 – 1.12 0.43 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.03 0.939 – 1.12 0.58 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.01 0.962 – 1.05 0.775 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.982 0.905 – 1.07 0.663 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.1 0.984 – 1.22 0.097 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.996 0.939 – 1.06 0.901 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.999 0.853 – 1.17 0.988 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 0.984 0.961 – 1.01 0.189 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 0.969 0.939 – 1 0.0559 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.952 0.834 – 1.09 0.46 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 0.941 0.897 – 0.987 0.0133 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 0.996 0.932 – 1.06 0.9 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 0.955 0.904 – 1.01 0.094 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1 0.942 – 1.06 0.988 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 0.998 0.937 – 1.06 0.943 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 0.993 0.825 – 1.2 0.944 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 0.984 0.947 – 1.02 0.413 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 0.995 0.904 – 1.1 0.92 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 1.17 0.982 – 1.41 0.0784 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 0.964 0.901 – 1.03 0.287 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.98 0.881 – 1.09 0.71 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.07 0.935 – 1.22 0.339 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.962 0.726 – 1.27 0.785 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.972 0.953 – 0.992 0.00506 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 0.971 0.951 – 0.99 0.00349 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 0.844 0.673 – 1.06 0.14 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.939 0.723 – 1.22 0.638 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.967 0.852 – 1.1 0.603 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 0.983 0.856 – 1.13 0.813 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.918 0.774 – 1.09 0.328 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 0.911 0.801 – 1.04 0.16 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 0.99 0.967 – 1.01 0.401 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.992 0.969 – 1.02 0.524 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.976 0.885 – 1.08 0.618 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 1 0.941 – 1.07 0.972 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 1 0.941 – 1.07 0.938 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 0.984 0.912 – 1.06 0.67 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.966 0.829 – 1.13 0.662 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 1.02 0.881 – 1.19 0.757 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 1.19 0.895 – 1.57 0.235 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.04 0.886 – 1.23 0.607 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 0.962 0.733 – 1.26 0.782 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.04 0.837 – 1.29 0.731 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 0.998 0.842 – 1.18 0.986 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.939 0.77 – 1.14 0.531 103 1059 all phecode
284 Aplastic anemia Hematopoietic 0.961 0.871 – 1.06 0.437 435 4357 all phecode
285 Other anemias Hematopoietic 0.997 0.979 – 1.02 0.755 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.03 0.905 – 1.16 0.694 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 0.963 0.89 – 1.04 0.341 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.915 0.826 – 1.01 0.0911 414 4147 all phecode
286 Coagulation defects Hematopoietic 0.983 0.919 – 1.05 0.624 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 0.97 0.882 – 1.07 0.533 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 0.914 0.748 – 1.12 0.375 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.977 0.867 – 1.1 0.704 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 0.969 0.755 – 1.24 0.803 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.945 0.76 – 1.18 0.613 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.973 0.878 – 1.08 0.605 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.05 0.996 – 1.1 0.0704 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.11 0.923 – 1.33 0.267 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 1.17 0.861 – 1.58 0.321 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 1.03 0.977 – 1.08 0.284 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 0.954 0.864 – 1.05 0.357 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1 0.795 – 1.27 0.977 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 0.999 0.966 – 1.03 0.966 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 1.01 0.972 – 1.05 0.647 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 1.01 0.971 – 1.04 0.702 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 0.988 0.778 – 1.25 0.921 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.02 0.954 – 1.1 0.533 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.974 0.863 – 1.1 0.668 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 1 0.96 – 1.04 0.985 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 1.01 0.925 – 1.11 0.785 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 0.907 0.806 – 1.02 0.106 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1 0.806 – 1.24 0.999 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.01 0.967 – 1.06 0.588 1929 19281 all phecode
290.1 Dementias Mental Disorders 1.02 0.958 – 1.09 0.523 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 1.01 0.92 – 1.12 0.784 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 1.04 0.905 – 1.2 0.557 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.989 0.912 – 1.07 0.78 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.1 0.867 – 1.38 0.444 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.97 0.904 – 1.04 0.387 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.09 0.913 – 1.3 0.343 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.896 0.796 – 1.01 0.0669 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 0.986 0.895 – 1.09 0.769 436 4376 all phecode
292 Neurological disorders Mental Disorders 0.981 0.952 – 1.01 0.208 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.965 0.915 – 1.02 0.18 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.859 0.742 – 0.995 0.043 190 1907 all phecode
292.3 Memory loss Mental Disorders 1.02 0.939 – 1.1 0.705 696 6978 all phecode
292.4 Altered mental status Mental Disorders 1 0.959 – 1.05 0.931 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 0.94 0.836 – 1.06 0.306 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 0.963 0.921 – 1.01 0.0963 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.983 0.918 – 1.05 0.62 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.996 0.928 – 1.07 0.917 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 1.06 0.972 – 1.15 0.188 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 0.942 0.808 – 1.1 0.45 178 1780 all phecode
295.3 Psychosis Mental Disorders 0.883 0.754 – 1.04 0.125 169 1710 all phecode
296 Mood disorders Mental Disorders 0.993 0.975 – 1.01 0.46 12372 123822 all phecode
296.1 Bipolar Mental Disorders 1.04 0.973 – 1.11 0.267 1059 10599 all phecode
296.2 Depression Mental Disorders 0.991 0.972 – 1.01 0.327 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 1.04 0.931 – 1.16 0.506 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.05 0.938 – 1.18 0.378 311 3070 all phecode
300 Anxiety disorders Mental Disorders 1 0.979 – 1.03 0.751 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 1 0.974 – 1.03 0.976 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 0.966 0.815 – 1.14 0.689 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.991 0.917 – 1.07 0.821 707 7065 all phecode
300.13 Phobia Mental Disorders 0.952 0.869 – 1.04 0.298 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.19 0.997 – 1.42 0.0536 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 0.946 0.72 – 1.24 0.688 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 1.05 0.873 – 1.27 0.589 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1 0.829 – 1.21 0.991 113 1129 all phecode
301 Personality disorders Mental Disorders 0.981 0.877 – 1.1 0.739 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.01 0.841 – 1.22 0.883 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.927 0.823 – 1.05 0.215 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.03 0.934 – 1.13 0.599 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 0.979 0.879 – 1.09 0.703 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 1.08 0.897 – 1.29 0.427 123 1229 all phecode
304 Adjustment reaction Mental Disorders 1.15 1.02 – 1.3 0.0239 293 2936 all phecode
305.2 Eating disorder Mental Disorders 1.08 0.866 – 1.35 0.495 90 900 all phecode
306 Other mental disorder Mental Disorders 0.986 0.973 – 0.998 0.022 28056 230087 all phecode
306.9 Tension headache Mental Disorders 1 0.892 – 1.12 0.982 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 1.03 0.819 – 1.29 0.805 76 770 all phecode
313.3 Autism Mental Disorders 1.1 0.836 – 1.44 0.507 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 0.977 0.874 – 1.09 0.677 351 3517 all phecode
315.1 Learning disorder Mental Disorders 1.13 0.962 – 1.32 0.139 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 0.988 0.793 – 1.23 0.917 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 1.01 0.979 – 1.04 0.633 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.943 0.72 – 1.23 0.67 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 0.989 0.971 – 1.01 0.239 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 0.984 0.963 – 1.01 0.149 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.02 0.951 – 1.1 0.575 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 0.989 0.974 – 1 0.126 19359 185465 all phecode
320 Meningitis Neurological 1.01 0.92 – 1.12 0.773 444 4447 all phecode
323 Encephalitis Neurological 0.944 0.845 – 1.05 0.307 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 0.927 0.722 – 1.19 0.551 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.12 0.991 – 1.26 0.0704 292 2916 all phecode
327 Sleep disorders Neurological 1.05 0.992 – 1.12 0.0864 1164 11659 all phecode
327.3 Sleep apnea Neurological 0.979 0.95 – 1.01 0.183 4428 44318 all phecode
327.4 Insomnia Neurological 1.06 0.902 – 1.25 0.475 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 1.04 0.872 – 1.25 0.639 136 1390 all phecode
331 Other cerebral degenerations Neurological 1.05 0.987 – 1.12 0.12 1142 11416 all phecode
331.1 Hydrocephalus Neurological 1.11 1.01 – 1.21 0.0321 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 0.997 0.904 – 1.1 0.959 430 4298 all phecode
332 Parkinson's disease Neurological 1 0.942 – 1.07 0.948 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.991 0.925 – 1.06 0.808 894 8954 all phecode
333.1 Essential tremor Neurological 0.948 0.825 – 1.09 0.449 216 2157 all phecode
333.2 Myoclonus Neurological 1 0.818 – 1.23 0.967 96 958 all phecode
333.4 Torsion dystonia Neurological 0.996 0.876 – 1.13 0.95 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 1.01 0.962 – 1.06 0.706 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 1.16 0.953 – 1.4 0.142 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 1.04 0.916 – 1.18 0.541 245 2446 all phecode
335 Multiple sclerosis Neurological 1.01 0.957 – 1.07 0.658 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 0.942 0.832 – 1.07 0.342 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.03 0.813 – 1.31 0.785 72 719 all phecode
338 Pain Neurological 1 0.929 – 1.08 0.987 768 7692 all phecode
338.1 Acute pain Neurological 0.985 0.889 – 1.09 0.769 394 3937 all phecode
338.2 Chronic pain Neurological 1.02 0.924 – 1.14 0.648 380 3817 all phecode
339 Other headache syndromes Neurological 0.98 0.958 – 1 0.0902 7819 78241 all phecode
340 Migraine Neurological 0.946 0.91 – 0.983 0.00467 2860 28602 all phecode
340.1 Migrain with aura Neurological 0.851 0.736 – 0.984 0.0294 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.07 0.945 – 1.22 0.281 252 2535 all phecode
342 Hemiplegia Neurological 0.958 0.909 – 1.01 0.11 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 0.971 0.823 – 1.15 0.73 145 1450 all phecode
344 Other paralytic syndromes Neurological 0.939 0.867 – 1.02 0.121 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.965 0.938 – 0.993 0.0161 5023 50270 all phecode
345.1 Epilepsy Neurological 0.946 0.882 – 1.01 0.115 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 0.952 0.864 – 1.05 0.322 439 4385 all phecode
345.12 Partial epilepsy Neurological 0.842 0.746 – 0.951 0.00543 277 2776 all phecode
345.3 Convulsions Neurological 0.952 0.912 – 0.995 0.0288 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.982 0.83 – 1.16 0.836 144 1438 all phecode
348 Other conditions of brain Neurological 0.951 0.883 – 1.03 0.191 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.03 0.908 – 1.17 0.624 268 2678 all phecode
348.4 Cerebral cysts Neurological 0.898 0.753 – 1.07 0.228 133 1350 all phecode
348.7 Coma Neurological 0.926 0.831 – 1.03 0.16 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 0.991 0.869 – 1.13 0.889 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 0.952 0.859 – 1.06 0.351 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.01 0.9 – 1.12 0.929 342 3414 all phecode
350 Abnormal movement Neurological 0.983 0.945 – 1.02 0.408 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 1.01 0.946 – 1.09 0.696 887 8852 all phecode
350.2 Abnormality of gait Neurological 0.97 0.921 – 1.02 0.244 1596 15969 all phecode
350.3 Lack of coordination Neurological 0.989 0.89 – 1.1 0.844 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.903 0.68 – 1.2 0.477 54 540 all phecode
351 Other peripheral nerve disorders Neurological 0.967 0.95 – 0.985 0.000411 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 1.01 0.954 – 1.07 0.762 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.997 0.905 – 1.1 0.949 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.01 0.945 – 1.09 0.724 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 0.971 0.914 – 1.03 0.348 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 1.12 0.932 – 1.36 0.223 114 1138 all phecode
353.2 Nerve root lesions Neurological 1.04 0.789 – 1.36 0.794 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.929 0.787 – 1.1 0.379 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 0.959 0.907 – 1.01 0.139 1361 13648 all phecode
358 Myoneural disorders Neurological 1.08 0.934 – 1.24 0.306 211 2109 all phecode
358.1 Myasthenia gravis Neurological 1.05 0.902 – 1.21 0.558 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 1 0.911 – 1.1 0.975 465 4646 all phecode
359.1 Muscular dystrophies Neurological 0.853 0.709 – 1.03 0.0939 122 1219 all phecode
359.2 Myopathy Neurological 1.03 0.923 – 1.15 0.606 360 3597 all phecode
360 Disorders of the globe Sense Organs 0.947 0.846 – 1.06 0.344 337 3367 all phecode
360.2 Progressive myopia Sense Organs 0.941 0.827 – 1.07 0.358 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 1.01 0.972 – 1.04 0.672 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.966 0.914 – 1.02 0.224 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 1.01 0.788 – 1.3 0.921 68 680 all phecode
362 Other retinal disorders Sense Organs 0.974 0.942 – 1.01 0.111 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.98 0.938 – 1.02 0.372 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.981 0.938 – 1.02 0.379 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.11 0.944 – 1.31 0.207 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 1.08 0.878 – 1.32 0.477 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.01 0.939 – 1.08 0.843 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.92 0.792 – 1.07 0.277 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.91 0.727 – 1.14 0.41 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.986 0.811 – 1.2 0.884 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.921 0.787 – 1.08 0.307 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 0.924 0.726 – 1.18 0.523 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.08 1 – 1.18 0.0479 647 6485 all phecode
364.1 Corneal opacity Sense Organs 0.856 0.69 – 1.06 0.16 90 910 all phecode
364.2 Corneal edema Sense Organs 1.06 0.849 – 1.33 0.589 79 800 all phecode
364.4 Corneal degenerations Sense Organs 1.13 0.98 – 1.3 0.092 201 2017 all phecode
364.41 Keratoconus Sense Organs 1.09 0.879 – 1.36 0.423 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 1.06 0.92 – 1.22 0.422 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.873 0.718 – 1.06 0.175 100 1000 all phecode
365 Glaucoma Sense Organs 0.99 0.96 – 1.02 0.54 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 0.981 0.921 – 1.05 0.554 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 0.983 0.923 – 1.05 0.604 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.979 0.906 – 1.06 0.598 698 6996 all phecode
366 Cataract Sense Organs 0.992 0.978 – 1.01 0.301 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 1.27 0.984 – 1.64 0.0668 69 700 all phecode
366.2 Senile cataract Sense Organs 0.977 0.955 – 1 0.0464 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 1.07 0.871 – 1.31 0.523 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.968 0.928 – 1.01 0.129 2408 24092 all phecode
367.1 Myopia Sense Organs 0.944 0.891 – 1 0.0516 1251 12519 all phecode
367.2 Astigmatism Sense Organs 1.06 0.918 – 1.23 0.407 190 1899 all phecode
367.8 Hypermetropia Sense Organs 0.968 0.85 – 1.1 0.623 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 0.977 0.904 – 1.05 0.548 719 7198 all phecode
368 Visual disturbances Sense Organs 0.985 0.949 – 1.02 0.422 2962 29648 all phecode
368.1 Amblyopia Sense Organs 1.03 0.946 – 1.13 0.482 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.03 0.954 – 1.11 0.456 727 7288 all phecode
368.3 Anisometropia Sense Organs 0.885 0.752 – 1.04 0.138 154 1548 all phecode
368.4 Visual field defects Sense Organs 1.01 0.897 – 1.13 0.927 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 1.04 0.96 – 1.14 0.309 612 6115 all phecode
369 Infection of the eye Sense Organs 1.11 1.02 – 1.21 0.0183 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 1.22 1.01 – 1.47 0.0391 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.976 0.848 – 1.12 0.729 213 2128 all phecode
370 Keratitis Sense Organs 1.02 0.901 – 1.15 0.786 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 0.899 0.758 – 1.07 0.223 141 1408 all phecode
371 Inflammation of the eye Sense Organs 1.04 1.01 – 1.08 0.0258 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.04 0.947 – 1.14 0.42 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 1.04 0.995 – 1.08 0.081 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 1.01 0.941 – 1.09 0.703 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 1 0.976 – 1.03 0.804 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 0.996 0.935 – 1.06 0.897 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 1.02 0.969 – 1.07 0.494 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 1 0.96 – 1.05 0.904 2204 22031 all phecode
375.2 Epiphora Sense Organs 0.982 0.917 – 1.05 0.593 898 8969 all phecode
376 Disorders of the orbit Sense Organs 0.964 0.778 – 1.2 0.741 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.921 0.829 – 1.02 0.127 361 3618 all phecode
377.1 Optic atrophy Sense Organs 0.706 0.547 – 0.91 0.00714 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.868 0.724 – 1.04 0.126 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.01 0.956 – 1.07 0.739 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1 0.935 – 1.07 0.972 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.975 0.849 – 1.12 0.723 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 1.03 0.91 – 1.17 0.628 275 2755 all phecode
379 Other disorders of eye Sense Organs 0.999 0.966 – 1.03 0.976 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 0.97 0.918 – 1.03 0.286 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.999 0.952 – 1.05 0.966 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.03 0.814 – 1.29 0.83 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.03 0.928 – 1.14 0.616 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.02 0.872 – 1.18 0.837 169 1690 all phecode
380 Disorders of external ear Sense Organs 1.05 0.97 – 1.14 0.22 642 6413 all phecode
380.1 Otitis externa Sense Organs 0.967 0.882 – 1.06 0.471 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 0.955 0.856 – 1.06 0.403 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.995 0.952 – 1.04 0.84 2150 21493 all phecode
381.1 Otitis media Sense Organs 0.99 0.943 – 1.04 0.698 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1 0.932 – 1.07 0.999 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 1.02 0.886 – 1.18 0.749 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 0.948 0.813 – 1.11 0.501 171 1709 all phecode
381.9 Otorrhea Sense Organs 0.95 0.838 – 1.08 0.422 281 2807 all phecode
382 Otalgia Sense Organs 0.911 0.812 – 1.02 0.116 308 3084 all phecode
383 Otosclerosis Sense Organs 1.06 0.943 – 1.19 0.33 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 0.998 0.942 – 1.06 0.938 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.01 0.947 – 1.08 0.773 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.943 0.877 – 1.01 0.117 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 0.975 0.898 – 1.06 0.541 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.956 0.838 – 1.09 0.507 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.995 0.948 – 1.05 0.853 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 1.08 0.995 – 1.18 0.0642 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 0.969 0.871 – 1.08 0.562 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 0.93 0.864 – 1 0.0539 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.992 0.963 – 1.02 0.618 4582 45806 all phecode
388 Other disorders of ear Sense Organs 0.929 0.808 – 1.07 0.303 202 2017 all phecode
389 Hearing loss Sense Organs 0.98 0.949 – 1.01 0.21 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 1.02 0.926 – 1.12 0.694 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 1.07 0.975 – 1.18 0.148 450 4497 all phecode
389.4 Tinnitus Sense Organs 0.964 0.881 – 1.06 0.43 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.01 0.98 – 1.04 0.537 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 1.03 0.992 – 1.07 0.119 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 0.986 0.93 – 1.04 0.635 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.04 0.978 – 1.11 0.208 1058 10566 all phecode
395 Heart valve disorders Circulatory System 1.01 0.977 – 1.04 0.586 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.03 0.993 – 1.07 0.114 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.962 0.852 – 1.09 0.54 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 0.936 0.768 – 1.14 0.516 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.992 0.815 – 1.21 0.935 97 970 all phecode
395.6 Heart valve replaced Circulatory System 0.966 0.916 – 1.02 0.205 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 1 0.942 – 1.07 0.904 1048 10468 all phecode
401 Hypertension Circulatory System 0.979 0.97 – 0.987 4.68e-07 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 0.978 0.97 – 0.987 3.76e-07 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 0.977 0.932 – 1.02 0.332 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 0.932 0.839 – 1.04 0.193 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.982 0.932 – 1.03 0.497 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 0.922 0.774 – 1.1 0.363 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 0.994 0.943 – 1.05 0.817 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 0.986 0.974 – 0.998 0.0239 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.964 0.937 – 0.992 0.0125 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 0.992 0.973 – 1.01 0.395 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 0.98 0.964 – 0.997 0.0177 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 0.987 0.973 – 1 0.0837 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.978 0.906 – 1.06 0.582 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.979 0.963 – 0.996 0.0137 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.991 0.934 – 1.05 0.767 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 0.998 0.951 – 1.05 0.926 1823 18228 all phecode
414.2 ASCVD Circulatory System 0.901 0.71 – 1.14 0.39 72 719 all phecode
415 Pulmonary heart disease Circulatory System 0.99 0.96 – 1.02 0.512 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.02 0.801 – 1.29 0.883 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.958 0.882 – 1.04 0.319 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 0.95 0.863 – 1.05 0.295 448 4475 all phecode
416 Cardiomegaly Circulatory System 0.982 0.944 – 1.02 0.366 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 0.983 0.971 – 0.995 0.00626 28599 270106 all phecode
418.1 Precordial pain Circulatory System 0.984 0.951 – 1.02 0.364 3551 35541 all phecode
420 Carditis Circulatory System 0.996 0.951 – 1.04 0.847 2106 21053 all phecode
420.1 Myocarditis Circulatory System 1.01 0.841 – 1.22 0.89 127 1267 all phecode
420.2 Pericarditis Circulatory System 1.01 0.951 – 1.07 0.815 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 1.07 0.933 – 1.23 0.329 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 0.935 0.772 – 1.13 0.489 113 1129 all phecode
420.3 Endocarditis Circulatory System 0.942 0.873 – 1.02 0.129 719 7194 all phecode
425 Cardiomyopathy Circulatory System 0.977 0.922 – 1.03 0.419 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.97 0.915 – 1.03 0.301 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.988 0.826 – 1.18 0.893 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.15 0.98 – 1.36 0.0863 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 0.878 0.674 – 1.14 0.334 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 0.979 0.955 – 1 0.09 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 0.952 0.911 – 0.996 0.0315 2114 21162 all phecode
426.21 First degree AV block Circulatory System 0.934 0.876 – 0.997 0.0406 986 9867 all phecode
426.23 Second degree AV block Circulatory System 0.944 0.857 – 1.04 0.244 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 0.925 0.851 – 1.01 0.0669 587 5868 all phecode
426.25 Other heart block Circulatory System 1 0.839 – 1.19 0.992 131 1318 all phecode
426.3 Bundle branch block Circulatory System 0.995 0.96 – 1.03 0.786 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 0.999 0.947 – 1.05 0.976 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 1 0.953 – 1.05 0.988 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.964 0.841 – 1.1 0.592 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 0.84 0.652 – 1.08 0.177 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.972 0.933 – 1.01 0.18 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.977 0.936 – 1.02 0.284 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 0.998 0.985 – 1.01 0.775 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1 0.968 – 1.04 0.86 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.994 0.953 – 1.04 0.762 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.06 0.988 – 1.13 0.108 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.01 0.989 – 1.02 0.472 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1 0.968 – 1.04 0.846 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.03 0.966 – 1.09 0.416 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.1 0.981 – 1.23 0.105 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 1.01 0.947 – 1.08 0.733 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.02 0.95 – 1.09 0.651 952 9541 all phecode
427.6 Premature beats Circulatory System 0.951 0.87 – 1.04 0.268 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 0.953 0.793 – 1.15 0.607 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 0.958 0.918 – 1 0.0555 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.04 0.938 – 1.15 0.459 402 4029 all phecode
427.9 Palpitations Circulatory System 0.986 0.954 – 1.02 0.419 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.986 0.959 – 1.01 0.303 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 0.989 0.946 – 1.03 0.638 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 0.986 0.956 – 1.02 0.373 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.04 0.961 – 1.12 0.336 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 1.02 0.792 – 1.32 0.875 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.03 0.939 – 1.12 0.561 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.08 0.927 – 1.25 0.338 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 0.99 0.944 – 1.04 0.686 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.01 0.943 – 1.08 0.757 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 0.987 0.915 – 1.06 0.726 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 1.01 0.89 – 1.14 0.916 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 0.973 0.951 – 0.994 0.013 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.986 0.929 – 1.05 0.651 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 0.939 0.819 – 1.08 0.365 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.977 0.947 – 1.01 0.154 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.977 0.929 – 1.03 0.375 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 0.972 0.936 – 1.01 0.152 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 0.962 0.92 – 1.01 0.0866 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 0.983 0.887 – 1.09 0.739 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.924 0.872 – 0.978 0.00626 1279 12783 all phecode
440 Atherosclerosis Circulatory System 1.02 0.963 – 1.08 0.519 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.916 0.758 – 1.11 0.362 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.06 0.99 – 1.14 0.0897 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 0.952 0.844 – 1.07 0.424 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 0.962 0.887 – 1.04 0.352 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.965 0.856 – 1.09 0.555 283 2827 all phecode
442 Other aneurysm Circulatory System 1.01 0.96 – 1.05 0.799 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 0.997 0.945 – 1.05 0.926 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.977 0.914 – 1.04 0.493 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.2 0.979 – 1.48 0.0793 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.1 0.944 – 1.29 0.215 169 1696 all phecode
442.4 Arterial dissection Circulatory System 0.921 0.705 – 1.2 0.545 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.04 0.902 – 1.2 0.58 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 0.976 0.944 – 1.01 0.142 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 0.97 0.913 – 1.03 0.326 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.03 0.932 – 1.15 0.524 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 0.967 0.935 – 1 0.0504 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.966 0.928 – 1.01 0.0942 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 0.954 0.892 – 1.02 0.176 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.932 0.854 – 1.02 0.112 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.981 0.913 – 1.05 0.595 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 1.05 0.909 – 1.22 0.486 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 0.975 0.878 – 1.08 0.634 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 0.985 0.86 – 1.13 0.827 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 0.987 0.933 – 1.04 0.646 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 1.01 0.942 – 1.08 0.777 868 8712 all phecode
448 Disease of capillaries Circulatory System 0.963 0.806 – 1.15 0.68 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.07 0.99 – 1.16 0.0857 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.995 0.963 – 1.03 0.775 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.998 0.965 – 1.03 0.904 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.951 0.872 – 1.04 0.247 564 5645 all phecode
454 Varicose veins Circulatory System 1.01 0.993 – 1.03 0.201 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1.02 0.997 – 1.04 0.0928 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.995 0.917 – 1.08 0.913 624 6325 all phecode
455 Hemorrhoids Circulatory System 0.998 0.985 – 1.01 0.8 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.11 0.955 – 1.29 0.177 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.939 0.758 – 1.16 0.564 97 967 all phecode
458 Hypotension Circulatory System 0.979 0.953 – 1.01 0.133 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 0.94 0.889 – 0.994 0.0311 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 0.91 0.797 – 1.04 0.166 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 0.984 0.95 – 1.02 0.354 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 0.973 0.958 – 0.989 0.000958 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 1.11 0.937 – 1.32 0.229 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 0.972 0.956 – 0.988 0.000502 16103 159422 all phecode
464 Acute sinusitis Respiratory 1.16 0.999 – 1.35 0.052 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.979 0.938 – 1.02 0.332 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 0.96 0.894 – 1.03 0.27 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.962 0.818 – 1.13 0.64 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.991 0.962 – 1.02 0.554 4654 46553 all phecode
471 Nasal polyps Respiratory 0.973 0.939 – 1.01 0.137 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.962 0.9 – 1.03 0.248 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1.01 0.965 – 1.05 0.789 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 1.01 0.828 – 1.23 0.917 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.938 0.827 – 1.06 0.322 264 2647 all phecode
473.4 Voice disturbance Respiratory 1.04 0.981 – 1.11 0.174 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 0.996 0.949 – 1.05 0.885 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 1.02 0.93 – 1.11 0.717 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.988 0.93 – 1.05 0.711 1122 11199 all phecode
475 Chronic sinusitis Respiratory 0.969 0.931 – 1.01 0.124 2589 25882 all phecode
476 Allergic rhinitis Respiratory 0.968 0.909 – 1.03 0.31 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 0.977 0.938 – 1.02 0.272 2447 24452 all phecode
478 Throat pain Respiratory 0.997 0.897 – 1.11 0.962 377 3789 all phecode
479 Other upper respiratory disease Respiratory 1 0.97 – 1.03 0.936 4074 40737 all phecode
480 Pneumonia Respiratory 1 0.981 – 1.02 0.951 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 0.982 0.957 – 1.01 0.156 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 0.971 0.945 – 0.997 0.0319 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.08 0.877 – 1.33 0.477 93 929 all phecode
480.2 Viral pneumonia Respiratory 0.987 0.776 – 1.25 0.912 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.05 0.854 – 1.28 0.666 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.07 0.994 – 1.15 0.0711 794 7951 all phecode
481 Influenza Respiratory 0.981 0.874 – 1.1 0.749 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.92 0.795 – 1.06 0.263 193 1930 all phecode
495 Asthma Respiratory 0.997 0.985 – 1.01 0.678 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 1.01 0.892 – 1.15 0.833 250 2510 all phecode
496 Chronic airway obstruction Respiratory 0.982 0.962 – 1 0.0794 10424 101546 all phecode
496.1 Emphysema Respiratory 1 0.957 – 1.06 0.843 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 0.972 0.936 – 1.01 0.14 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 0.977 0.939 – 1.02 0.237 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 1 0.954 – 1.05 0.982 1885 18859 all phecode
497 Bronchitis Respiratory 0.971 0.895 – 1.05 0.482 626 6267 all phecode
500 Lung disease due to external agents Respiratory 0.942 0.852 – 1.04 0.247 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.95 0.756 – 1.19 0.66 79 784 all phecode
500.2 Pneumoconiosis Respiratory 0.944 0.83 – 1.07 0.382 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 0.983 0.907 – 1.07 0.679 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.04 0.969 – 1.11 0.29 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 0.889 0.812 – 0.974 0.0117 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.11 0.988 – 1.24 0.0789 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.23 0.938 – 1.61 0.134 61 610 all phecode
506 Empyema and pneumothorax Respiratory 0.99 0.931 – 1.05 0.751 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 0.993 0.968 – 1.02 0.614 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.994 0.949 – 1.04 0.808 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.01 0.969 – 1.05 0.684 2599 26031 all phecode
509.1 Respiratory failure Respiratory 1.01 0.964 – 1.06 0.712 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 1.02 0.967 – 1.07 0.536 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 0.966 0.813 – 1.15 0.695 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.02 0.921 – 1.13 0.689 386 3863 all phecode
510 Other diseases of lung Respiratory 1.02 0.943 – 1.09 0.676 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 0.993 0.972 – 1.01 0.516 9031 90349 all phecode
512.1 Wheezing Respiratory 1.06 0.926 – 1.22 0.383 220 2196 all phecode
512.2 Painful respiration Respiratory 1.04 0.905 – 1.2 0.555 207 2075 all phecode
512.7 Shortness of breath Respiratory 0.986 0.959 – 1.01 0.29 5842 58498 all phecode
512.8 Cough Respiratory 0.996 0.959 – 1.03 0.83 2866 28642 all phecode
512.9 Other dyspnea Respiratory 0.987 0.922 – 1.06 0.697 914 9124 all phecode
513 Respiratory abnormalities Respiratory 1.03 0.949 – 1.12 0.466 611 6112 all phecode
513.3 Hypoventilation Respiratory 1.1 0.888 – 1.37 0.376 83 830 all phecode
513.4 Hyperventilation Respiratory 1.03 0.907 – 1.16 0.69 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 0.912 0.773 – 1.07 0.271 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 1.01 0.971 – 1.06 0.57 2465 24673 all phecode
516 Abnormal sputum Respiratory 1 0.957 – 1.05 0.964 2132 21335 all phecode
516.1 Hemoptysis Respiratory 1.01 0.961 – 1.05 0.822 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.999 0.978 – 1.02 0.898 9366 93681 all phecode
519.2 Respiratory complications Respiratory 0.86 0.768 – 0.964 0.00968 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.997 0.976 – 1.02 0.821 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.09 0.973 – 1.23 0.134 303 3049 all phecode
520 Disorders of tooth development Digestive 0.975 0.931 – 1.02 0.273 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.883 0.669 – 1.16 0.377 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 0.985 0.944 – 1.03 0.494 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 0.992 0.956 – 1.03 0.683 3016 30245 all phecode
521.1 Dental caries Digestive 0.987 0.951 – 1.03 0.506 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 0.981 0.934 – 1.03 0.442 1774 17750 all phecode
522.5 Periapical abscess Digestive 0.985 0.928 – 1.05 0.632 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 0.955 0.908 – 1 0.0734 1681 16812 all phecode
523.1 Gingivitis Digestive 0.986 0.813 – 1.19 0.882 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 0.954 0.898 – 1.01 0.128 1165 11650 all phecode
523.31 Acute periodontitis Digestive 0.918 0.848 – 0.995 0.0366 666 6667 all phecode
523.32 Chronic periodontitis Digestive 1.01 0.929 – 1.11 0.767 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.03 0.922 – 1.16 0.571 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.03 0.917 – 1.16 0.601 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.956 0.919 – 0.995 0.0261 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.16 0.913 – 1.46 0.229 72 720 all phecode
526 Diseases of the jaws Digestive 1.01 0.943 – 1.08 0.796 928 9279 all phecode
526.1 Cysts of the jaws Digestive 0.943 0.84 – 1.06 0.313 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.15 0.881 – 1.49 0.307 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.08 0.942 – 1.23 0.281 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.06 0.925 – 1.21 0.41 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.979 0.802 – 1.2 0.836 110 1098 all phecode
526.9 Jaw disease NOS Digestive 1 0.876 – 1.14 0.984 233 2329 all phecode
527 Diseases of the salivary glands Digestive 0.983 0.909 – 1.06 0.656 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 0.854 0.68 – 1.07 0.174 84 838 all phecode
527.2 Sialoadenitis Digestive 0.98 0.88 – 1.09 0.72 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 1.1 0.858 – 1.41 0.451 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.1 0.911 – 1.32 0.326 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.979 0.947 – 1.01 0.204 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 0.98 0.892 – 1.08 0.675 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.979 0.882 – 1.09 0.688 389 3884 all phecode
528.12 Oral aphthae Digestive 0.895 0.714 – 1.12 0.334 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.11 0.95 – 1.3 0.19 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 0.916 0.763 – 1.1 0.348 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 0.897 0.73 – 1.1 0.298 94 940 all phecode
528.5 Diseases of lips Digestive 0.948 0.877 – 1.02 0.173 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.05 0.932 – 1.18 0.419 308 3079 all phecode
528.7 Sialolithiasis Digestive 0.907 0.808 – 1.02 0.0981 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 0.979 0.923 – 1.04 0.494 1232 12312 all phecode
529.1 Glossitis Digestive 0.947 0.84 – 1.07 0.373 299 2986 all phecode
530 Diseases of esophagus Digestive 0.986 0.974 – 0.997 0.0117 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.985 0.974 – 0.997 0.0112 31253 272429 all phecode
530.11 GERD Digestive 0.986 0.972 – 0.999 0.0381 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 0.978 0.951 – 1.01 0.123 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 0.995 0.976 – 1.02 0.648 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.997 0.948 – 1.05 0.905 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 0.971 0.927 – 1.02 0.226 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 1.02 0.939 – 1.11 0.653 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.984 0.83 – 1.17 0.851 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.978 0.877 – 1.09 0.693 341 3416 all phecode
530.9 Heartburn Digestive 0.968 0.925 – 1.01 0.16 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.986 0.962 – 1.01 0.24 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.978 0.902 – 1.06 0.59 637 6374 all phecode
531.2 Gastric ulcer Digestive 0.985 0.954 – 1.02 0.349 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 0.989 0.952 – 1.03 0.565 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 0.935 0.846 – 1.03 0.191 427 4268 all phecode
532 Dysphagia Digestive 0.998 0.972 – 1.02 0.862 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 0.992 0.98 – 1 0.216 28078 261548 all phecode
535.1 Acute gastritis Digestive 0.986 0.928 – 1.05 0.637 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 0.946 0.849 – 1.05 0.316 370 3687 all phecode
535.6 Duodenitis Digestive 1.02 0.993 – 1.04 0.158 7592 75928 all phecode
535.8 Other specified gastritis Digestive 0.998 0.975 – 1.02 0.853 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.05 0.87 – 1.27 0.611 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.02 0.894 – 1.16 0.803 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 0.973 0.939 – 1.01 0.128 3391 33907 all phecode
540 Appendiceal conditions Digestive 0.984 0.948 – 1.02 0.389 3088 30890 all phecode
540.1 Appendicitis Digestive 0.984 0.947 – 1.02 0.409 2895 28963 all phecode
540.11 Acute appendicitis Digestive 0.973 0.934 – 1.01 0.179 2601 26019 all phecode
550 Abdominal hernia Digestive 0.993 0.983 – 1 0.191 45429 282640 all phecode
550.1 Inguinal hernia Digestive 1.01 0.991 – 1.02 0.382 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 0.986 0.974 – 0.999 0.031 26494 238953 all phecode
550.3 Femoral hernia Digestive 1.03 0.955 – 1.12 0.406 651 6504 all phecode
550.4 Umbilical hernia Digestive 0.988 0.955 – 1.02 0.502 3705 37072 all phecode
550.5 Ventral hernia Digestive 1.01 0.975 – 1.05 0.579 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.03 1 – 1.06 0.044 4444 44442 all phecode
555.1 Regional enteritis Digestive 1.04 0.988 – 1.09 0.141 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 1.03 0.997 – 1.07 0.0734 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.03 0.94 – 1.12 0.551 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 1 0.943 – 1.07 0.902 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 0.988 0.913 – 1.07 0.769 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.05 0.936 – 1.18 0.387 299 2987 all phecode
557.1 Celiac disease Digestive 1.02 0.969 – 1.07 0.504 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 0.974 0.958 – 0.991 0.00201 15492 155105 all phecode
559 Ileostomy status Digestive 1.01 0.956 – 1.06 0.844 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 0.988 0.956 – 1.02 0.465 3936 39337 all phecode
560.1 Paralytic ileus Digestive 0.981 0.898 – 1.07 0.68 523 5231 all phecode
560.2 Impaction of intestine Digestive 0.954 0.842 – 1.08 0.455 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.983 0.916 – 1.06 0.635 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 0.991 0.957 – 1.03 0.616 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 0.99 0.974 – 1.01 0.221 15772 157686 all phecode
561.1 Diarrhea Digestive 1.03 0.936 – 1.13 0.544 466 4653 all phecode
561.2 Flatulence Digestive 0.981 0.933 – 1.03 0.44 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 0.976 0.964 – 0.989 0.000233 26714 211692 all phecode
562.1 Diverticulosis Digestive 0.977 0.965 – 0.99 0.000354 26672 211642 all phecode
563 Constipation Digestive 0.97 0.95 – 0.989 0.0028 10314 103140 all phecode
564 Functional digestive disorders Digestive 0.979 0.966 – 0.993 0.00335 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 0.97 0.944 – 0.998 0.0325 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 0.991 0.942 – 1.04 0.732 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 0.982 0.965 – 0.998 0.0291 15186 151648 all phecode
565 Anal and rectal conditions Digestive 1 0.983 – 1.02 0.977 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 0.999 0.975 – 1.02 0.93 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 0.966 0.904 – 1.03 0.305 929 9293 all phecode
568 Other disorders of peritoneum Digestive 1.02 0.985 – 1.06 0.252 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.02 0.979 – 1.05 0.407 3101 30987 all phecode
569 Other disorders of intestine Digestive 0.981 0.951 – 1.01 0.247 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.963 0.812 – 1.14 0.665 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 0.933 0.85 – 1.02 0.14 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 0.944 0.909 – 0.981 0.00291 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 0.946 0.899 – 0.994 0.0293 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.04 0.866 – 1.25 0.663 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 0.905 0.797 – 1.03 0.124 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.946 0.886 – 1.01 0.0986 976 9804 all phecode
571.81 Portal hypertension Digestive 0.907 0.83 – 0.99 0.0299 528 5285 all phecode
572 Ascites (non malignant) Digestive 1.02 0.968 – 1.08 0.444 1544 15454 all phecode
573 Other disorders of liver Digestive 0.948 0.899 – 1 0.0493 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 0.905 0.734 – 1.12 0.351 96 960 all phecode
573.3 Hepatomegaly Digestive 1 0.888 – 1.13 0.999 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 1.03 0.963 – 1.1 0.386 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 0.95 0.917 – 0.983 0.00382 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.04 0.901 – 1.19 0.611 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 0.985 0.969 – 1 0.0664 15607 156123 all phecode
574.1 Cholelithiasis Digestive 0.985 0.967 – 1 0.0838 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.998 0.947 – 1.05 0.95 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.999 0.972 – 1.03 0.959 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 1 0.964 – 1.04 0.869 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.979 0.942 – 1.02 0.297 2748 27523 all phecode
575 Other biliary tract disease Digestive 0.966 0.935 – 0.998 0.0397 3867 38724 all phecode
575.1 Cholangitis Digestive 1.02 0.933 – 1.13 0.613 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 0.946 0.879 – 1.02 0.138 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.954 0.868 – 1.05 0.331 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 0.968 0.917 – 1.02 0.248 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 0.963 0.904 – 1.03 0.251 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.08 0.971 – 1.21 0.151 348 3488 all phecode
577 Diseases of pancreas Digestive 0.977 0.939 – 1.02 0.239 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 0.978 0.934 – 1.02 0.335 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 0.964 0.882 – 1.05 0.415 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.973 0.875 – 1.08 0.621 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 0.989 0.975 – 1 0.147 20626 206278 all phecode
578.1 Hematemesis Digestive 0.988 0.943 – 1.04 0.624 1958 19564 all phecode
578.2 Blood in stool Digestive 0.992 0.952 – 1.03 0.681 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 0.988 0.97 – 1.01 0.177 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.997 0.969 – 1.03 0.814 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.01 0.955 – 1.06 0.812 1548 15498 all phecode
579.2 Splenomegaly Digestive 1.06 0.957 – 1.17 0.273 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.963 0.916 – 1.01 0.143 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.967 0.918 – 1.02 0.207 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 0.948 0.89 – 1.01 0.0985 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.17 0.924 – 1.48 0.195 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.03 0.855 – 1.24 0.768 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.924 0.862 – 0.99 0.024 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.925 0.842 – 1.02 0.103 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.06 0.925 – 1.2 0.423 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.04 0.916 – 1.19 0.517 253 2529 all phecode
585 Renal failure Genitourinary 0.97 0.946 – 0.994 0.0151 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 0.968 0.939 – 0.998 0.0393 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 0.982 0.931 – 1.04 0.518 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.971 0.933 – 1.01 0.157 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 1.01 0.925 – 1.11 0.761 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 0.987 0.953 – 1.02 0.471 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1 0.867 – 1.16 0.98 208 2089 all phecode
586.11 Small kidney Genitourinary 0.977 0.835 – 1.14 0.767 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 0.99 0.934 – 1.05 0.726 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.03 0.829 – 1.29 0.766 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.985 0.921 – 1.05 0.661 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 1.08 0.969 – 1.2 0.167 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 0.898 0.73 – 1.1 0.306 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.01 0.843 – 1.22 0.884 116 1158 all phecode
590 Pyelonephritis Genitourinary 0.98 0.927 – 1.04 0.488 1328 13285 all phecode
591 Urinary tract infection Genitourinary 0.991 0.972 – 1.01 0.312 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 0.979 0.943 – 1.02 0.264 2966 29661 all phecode
592.1 Cystitis Genitourinary 0.977 0.941 – 1.02 0.241 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 0.981 0.822 – 1.17 0.832 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 0.987 0.921 – 1.06 0.703 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.98 0.862 – 1.11 0.762 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.951 0.814 – 1.11 0.521 165 1662 all phecode
593 Hematuria Genitourinary 1 0.988 – 1.02 0.651 16068 160204 all phecode
594 Urinary calculus Genitourinary 0.987 0.962 – 1.01 0.308 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 0.986 0.951 – 1.02 0.46 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.03 0.955 – 1.11 0.458 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 1 0.96 – 1.04 0.952 2401 24024 all phecode
594.8 Renal colic Genitourinary 0.945 0.903 – 0.989 0.0149 2050 20500 all phecode
595 Hydronephrosis Genitourinary 1.03 0.985 – 1.08 0.183 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 0.996 0.976 – 1.02 0.712 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 0.999 0.953 – 1.05 0.953 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 1.03 0.981 – 1.09 0.224 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.02 0.99 – 1.06 0.172 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.02 0.988 – 1.06 0.196 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 1.06 0.839 – 1.35 0.607 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 0.992 0.959 – 1.03 0.669 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.95 0.844 – 1.07 0.4 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1 0.985 – 1.01 0.97 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 0.978 0.834 – 1.15 0.782 166 1670 all phecode
599.2 Retention of urine Genitourinary 0.981 0.957 – 1.01 0.131 6718 67168 all phecode
599.3 Dysuria Genitourinary 0.988 0.931 – 1.05 0.69 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 0.999 0.978 – 1.02 0.959 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.01 0.976 – 1.04 0.639 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 0.956 0.783 – 1.17 0.657 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 0.911 0.706 – 1.17 0.472 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 0.97 0.925 – 1.02 0.203 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 1.01 0.986 – 1.03 0.541 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.974 0.931 – 1.02 0.255 2081 20818 all phecode
601.1 Prostatitis Genitourinary 0.965 0.915 – 1.02 0.178 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 0.934 0.815 – 1.07 0.321 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 0.985 0.92 – 1.06 0.67 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 0.737 0.567 – 0.959 0.0229 59 588 all phecode
601.4 Balanoposthitis Genitourinary 1.05 0.93 – 1.18 0.441 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.95 0.843 – 1.07 0.398 303 3019 all phecode
602 Other disorders of prostate Genitourinary 1 0.946 – 1.06 0.98 1341 13408 all phecode
603 Other disorders of testis Genitourinary 1.03 0.983 – 1.08 0.221 2150 21512 all phecode
603.1 Hydrocele Genitourinary 1.05 0.997 – 1.12 0.0652 1339 13402 all phecode
604 Disorders of penis Genitourinary 1.01 0.972 – 1.04 0.673 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.01 0.974 – 1.05 0.526 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 0.846 0.747 – 0.958 0.00836 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 0.981 0.944 – 1.02 0.338 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.957 0.832 – 1.1 0.536 214 2138 all phecode
609.1 Infertility, male Genitourinary 0.881 0.677 – 1.15 0.344 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.961 0.822 – 1.12 0.62 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 0.976 0.937 – 1.02 0.258 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 0.952 0.89 – 1.02 0.156 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 0.906 0.806 – 1.02 0.0941 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 0.916 0.814 – 1.03 0.142 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 1 0.95 – 1.06 0.879 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.04 0.964 – 1.13 0.297 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.05 0.993 – 1.1 0.0931 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 1.15 0.865 – 1.52 0.343 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 1.04 0.989 – 1.1 0.119 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.973 0.909 – 1.04 0.432 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.971 0.906 – 1.04 0.41 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 0.984 0.782 – 1.24 0.894 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 0.986 0.937 – 1.04 0.571 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 0.971 0.9 – 1.05 0.456 720 7210 all phecode
613.5 Mastodynia Genitourinary 0.852 0.678 – 1.07 0.166 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.988 0.915 – 1.07 0.761 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 1.02 0.907 – 1.14 0.791 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 1.08 0.933 – 1.24 0.314 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1 0.974 – 1.03 0.963 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.975 0.936 – 1.02 0.218 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1 0.935 – 1.08 0.903 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.916 0.708 – 1.19 0.506 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.988 0.894 – 1.09 0.805 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.05 0.946 – 1.18 0.339 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.03 0.908 – 1.16 0.679 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.01 0.974 – 1.06 0.51 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1 0.948 – 1.06 0.893 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.98 0.887 – 1.08 0.684 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1 0.928 – 1.08 0.994 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.14 1 – 1.29 0.0446 274 2737 all phecode
615 Endometriosis Genitourinary 0.992 0.961 – 1.03 0.647 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 0.967 0.861 – 1.09 0.577 304 3037 all phecode
618 Genital prolapse Genitourinary 0.979 0.96 – 0.997 0.0255 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 0.967 0.944 – 0.991 0.00638 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.995 0.968 – 1.02 0.747 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.967 0.883 – 1.06 0.478 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.995 0.921 – 1.08 0.908 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.99 0.969 – 1.01 0.39 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.03 0.955 – 1.11 0.439 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 0.994 0.959 – 1.03 0.727 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.995 0.957 – 1.03 0.785 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.02 0.972 – 1.07 0.411 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.978 0.925 – 1.03 0.442 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 1.04 0.824 – 1.31 0.758 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 0.978 0.92 – 1.04 0.488 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 0.991 0.971 – 1.01 0.366 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.989 0.967 – 1.01 0.362 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.98 0.946 – 1.01 0.25 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 0.97 0.916 – 1.03 0.305 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 0.994 0.924 – 1.07 0.862 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.979 0.858 – 1.12 0.753 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.99 0.897 – 1.09 0.839 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 0.998 0.972 – 1.03 0.907 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.984 0.947 – 1.02 0.404 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 1.03 0.967 – 1.09 0.396 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.976 0.96 – 0.992 0.0042 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.972 0.955 – 0.989 0.00168 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 1.12 0.921 – 1.36 0.256 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 0.961 0.941 – 0.981 0.000201 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 0.997 0.952 – 1.04 0.906 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.975 0.943 – 1.01 0.134 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 0.992 0.944 – 1.04 0.741 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 1.01 0.857 – 1.19 0.888 159 1587 all phecode
626.8 Infertility, female Genitourinary 0.974 0.922 – 1.03 0.359 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.02 0.996 – 1.04 0.108 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 1.01 0.989 – 1.03 0.323 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 1.13 0.973 – 1.32 0.109 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1 0.945 – 1.07 0.878 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.969 0.864 – 1.09 0.589 310 3097 all phecode
628 Ovarian cyst Genitourinary 0.998 0.969 – 1.03 0.887 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.01 0.984 – 1.04 0.384 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.06 0.994 – 1.13 0.0757 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.01 0.9 – 1.13 0.889 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.02 0.974 – 1.07 0.382 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.01 0.938 – 1.08 0.877 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.03 0.976 – 1.1 0.262 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.963 0.923 – 1.01 0.0865 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.956 0.88 – 1.04 0.289 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.975 0.916 – 1.04 0.432 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 0.955 0.75 – 1.22 0.711 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.02 0.956 – 1.08 0.593 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.996 0.885 – 1.12 0.95 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.912 0.793 – 1.05 0.195 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.943 0.797 – 1.12 0.494 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.03 0.971 – 1.09 0.328 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.991 0.948 – 1.03 0.67 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.977 0.753 – 1.27 0.864 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.868 0.767 – 0.982 0.0249 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.14 0.937 – 1.38 0.194 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.03 0.889 – 1.2 0.686 193 1922 all phecode
650 Normal delivery Pregnancy Complications 1.04 0.993 – 1.09 0.0974 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 1.02 0.913 – 1.14 0.734 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.982 0.934 – 1.03 0.466 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.998 0.945 – 1.05 0.951 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.19 0.938 – 1.51 0.151 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.989 0.958 – 1.02 0.517 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.995 0.825 – 1.2 0.961 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 1 0.96 – 1.05 0.874 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.996 0.911 – 1.09 0.926 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.998 0.968 – 1.03 0.879 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1 0.959 – 1.04 0.981 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.912 0.78 – 1.07 0.248 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.927 0.818 – 1.05 0.238 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.913 0.706 – 1.18 0.488 63 624 all phecode
679 Complications of in utero procedures Dermatologic 1.09 0.822 – 1.44 0.549 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 1 0.976 – 1.02 0.984 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.986 0.905 – 1.08 0.754 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.03 0.937 – 1.12 0.585 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.992 0.965 – 1.02 0.564 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.993 0.966 – 1.02 0.639 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.991 0.964 – 1.02 0.544 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.03 0.951 – 1.13 0.428 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.03 0.973 – 1.09 0.321 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.01 0.969 – 1.06 0.608 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 0.975 0.897 – 1.06 0.561 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 1.04 0.934 – 1.16 0.458 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1.01 0.927 – 1.11 0.759 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.02 0.973 – 1.06 0.445 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 0.96 0.849 – 1.09 0.514 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 1.11 0.903 – 1.36 0.326 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 0.973 0.937 – 1.01 0.167 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.985 0.958 – 1.01 0.267 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.949 0.748 – 1.2 0.669 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.904 0.688 – 1.19 0.468 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 0.961 0.799 – 1.16 0.677 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.99 0.927 – 1.06 0.753 986 9854 all phecode
694.1 Vitiligo Dermatologic 0.969 0.751 – 1.25 0.812 60 599 all phecode
694.2 Other dyschromia Dermatologic 0.99 0.92 – 1.07 0.789 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 1.04 0.859 – 1.26 0.692 117 1170 all phecode
695 Erythematous conditions Dermatologic 0.971 0.931 – 1.01 0.176 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 0.995 0.819 – 1.21 0.961 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 1.01 0.857 – 1.2 0.868 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 1.04 0.809 – 1.35 0.739 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.961 0.765 – 1.21 0.732 73 727 all phecode
695.3 Rosacea Dermatologic 0.971 0.864 – 1.09 0.625 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 0.943 0.852 – 1.04 0.251 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.873 0.73 – 1.04 0.136 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 0.937 0.839 – 1.05 0.253 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 0.993 0.922 – 1.07 0.851 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 0.952 0.832 – 1.09 0.469 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 0.997 0.791 – 1.26 0.983 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 0.96 0.872 – 1.06 0.396 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 0.996 0.953 – 1.04 0.84 2252 22509 all phecode
696.4 Psoriasis Dermatologic 0.993 0.951 – 1.04 0.769 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 0.986 0.938 – 1.04 0.585 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.04 0.963 – 1.12 0.319 706 7052 all phecode
697 Sarcoidosis Dermatologic 1.04 0.955 – 1.14 0.35 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 1.02 0.951 – 1.1 0.525 782 7814 all phecode
700 Corns and callosities Dermatologic 1.05 0.935 – 1.19 0.387 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.01 0.977 – 1.04 0.646 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 1.22 0.968 – 1.53 0.0925 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.01 0.973 – 1.06 0.496 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 0.937 0.724 – 1.21 0.62 61 610 all phecode
701.4 Keloid scar Dermatologic 1.1 0.954 – 1.26 0.191 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 0.944 0.857 – 1.04 0.24 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.06 0.861 – 1.29 0.601 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.992 0.965 – 1.02 0.589 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 0.989 0.95 – 1.03 0.582 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 1 0.968 – 1.04 0.829 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 0.975 0.875 – 1.09 0.646 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 0.969 0.907 – 1.04 0.347 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 0.983 0.956 – 1.01 0.248 5267 52727 all phecode
704.1 Alopecia Dermatologic 1.05 0.875 – 1.25 0.62 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.09 0.863 – 1.38 0.461 76 759 all phecode
705 Disorders of sweat glands Dermatologic 1.07 0.937 – 1.23 0.311 228 2287 all phecode
705.3 Hidradenitis Dermatologic 1.09 0.943 – 1.27 0.237 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 1.01 0.931 – 1.1 0.758 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 1 0.981 – 1.03 0.766 8317 83195 all phecode
706.1 Acne Dermatologic 1.11 0.882 – 1.39 0.379 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 0.997 0.976 – 1.02 0.803 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 0.94 0.898 – 0.985 0.00919 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 0.901 0.842 – 0.964 0.00254 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.964 0.931 – 0.998 0.0395 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 1.06 0.968 – 1.16 0.209 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 0.993 0.852 – 1.16 0.926 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.04 0.811 – 1.33 0.766 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.945 0.909 – 0.983 0.00465 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.02 0.941 – 1.11 0.58 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 1.02 0.932 – 1.11 0.696 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.07 0.922 – 1.24 0.377 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.05 0.945 – 1.16 0.376 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 0.891 0.807 – 0.983 0.0218 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 0.888 0.792 – 0.995 0.0413 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 0.882 0.708 – 1.1 0.262 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.13 0.954 – 1.34 0.156 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.13 0.878 – 1.46 0.341 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.991 0.963 – 1.02 0.563 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.987 0.957 – 1.02 0.411 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.996 0.947 – 1.05 0.885 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.878 0.726 – 1.06 0.179 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.02 0.937 – 1.1 0.69 618 6177 all phecode
716 Other arthropathies Musculoskeletal 0.989 0.978 – 1 0.0446 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.997 0.964 – 1.03 0.884 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.99 0.974 – 1.01 0.229 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 0.987 0.976 – 0.998 0.0232 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.03 0.974 – 1.1 0.279 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 0.96 0.929 – 0.993 0.018 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 0.989 0.966 – 1.01 0.346 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.998 0.969 – 1.03 0.876 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.885 0.762 – 1.03 0.108 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 0.9 0.809 – 1 0.0558 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 1 0.982 – 1.03 0.722 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.07 0.973 – 1.17 0.171 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.985 0.948 – 1.02 0.442 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.08 0.857 – 1.36 0.512 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.03 0.999 – 1.06 0.0562 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 1.11 1.02 – 1.22 0.0198 517 5173 all phecode
723.1 Torticollis Musculoskeletal 1.28 1.04 – 1.58 0.0197 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 0.986 0.943 – 1.03 0.541 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 0.95 0.859 – 1.05 0.319 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 0.96 0.868 – 1.06 0.426 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 0.848 0.658 – 1.09 0.2 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1 0.954 – 1.06 0.903 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1 0.986 – 1.02 0.759 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 0.995 0.974 – 1.02 0.618 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 0.912 0.817 – 1.02 0.102 334 3336 all phecode
726.3 Bursitis Musculoskeletal 1.02 0.949 – 1.09 0.618 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.997 0.973 – 1.02 0.812 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1 0.961 – 1.04 0.998 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 1.14 0.933 – 1.39 0.2 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.984 0.948 – 1.02 0.385 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 1.08 0.993 – 1.18 0.0728 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.03 0.92 – 1.14 0.641 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.865 0.731 – 1.02 0.0907 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.976 0.944 – 1.01 0.166 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.977 0.883 – 1.08 0.655 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 0.987 0.955 – 1.02 0.443 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.979 0.946 – 1.01 0.243 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 0.987 0.961 – 1.01 0.332 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.986 0.925 – 1.05 0.68 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 0.909 0.74 – 1.12 0.366 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.992 0.878 – 1.12 0.901 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.999 0.881 – 1.13 0.982 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 0.974 0.886 – 1.07 0.578 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.977 0.847 – 1.13 0.749 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.883 0.679 – 1.15 0.353 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.992 0.944 – 1.04 0.737 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 1.14 1.02 – 1.29 0.0248 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.993 0.909 – 1.09 0.885 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 0.987 0.827 – 1.18 0.885 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.03 0.967 – 1.09 0.388 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 0.903 0.752 – 1.08 0.273 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 0.994 0.973 – 1.01 0.555 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 1.14 0.982 – 1.32 0.0848 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 0.988 0.96 – 1.02 0.398 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.98 0.936 – 1.03 0.402 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 0.937 0.89 – 0.987 0.0137 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.989 0.964 – 1.01 0.367 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 1.03 0.982 – 1.09 0.203 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.01 0.891 – 1.15 0.833 248 2476 all phecode
737 Curvature of spine Musculoskeletal 1.01 0.948 – 1.07 0.784 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.02 0.954 – 1.08 0.616 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.99 0.944 – 1.04 0.673 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.986 0.935 – 1.04 0.591 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 0.98 0.894 – 1.07 0.669 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 1 0.991 – 1.02 0.623 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.01 0.991 – 1.02 0.402 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.999 0.977 – 1.02 0.892 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.02 0.91 – 1.13 0.779 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1 0.923 – 1.09 0.939 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.997 0.978 – 1.02 0.734 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.03 0.995 – 1.07 0.0943 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 0.997 0.81 – 1.23 0.975 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 1.09 0.998 – 1.18 0.0563 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 0.926 0.784 – 1.09 0.364 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 1.05 0.99 – 1.1 0.106 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 0.868 0.716 – 1.05 0.149 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 1.01 0.77 – 1.33 0.94 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.983 0.946 – 1.02 0.387 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 0.989 0.885 – 1.11 0.847 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.14 0.918 – 1.42 0.235 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 0.938 0.857 – 1.03 0.17 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 0.998 0.953 – 1.04 0.928 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1 0.977 – 1.02 0.983 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 0.997 0.972 – 1.02 0.848 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.99 0.964 – 1.02 0.494 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1.06 0.972 – 1.17 0.179 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 1.08 0.982 – 1.18 0.116 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.03 0.959 – 1.11 0.412 815 8144 all phecode
745 Pain in joint Musculoskeletal 0.99 0.967 – 1.01 0.379 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.974 0.937 – 1.01 0.184 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.976 0.937 – 1.02 0.232 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.976 0.897 – 1.06 0.583 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.04 0.914 – 1.19 0.523 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.963 0.917 – 1.01 0.125 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.916 0.782 – 1.07 0.279 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.16 0.882 – 1.52 0.29 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.01 0.895 – 1.13 0.918 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 1.07 0.986 – 1.16 0.109 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.1 0.982 – 1.24 0.0979 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.05 0.903 – 1.22 0.538 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.04 0.933 – 1.16 0.475 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.06 0.921 – 1.21 0.429 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.01 0.835 – 1.22 0.913 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.992 0.941 – 1.05 0.775 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.01 0.93 – 1.09 0.897 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.974 0.886 – 1.07 0.584 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.998 0.869 – 1.15 0.976 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.979 0.912 – 1.05 0.563 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 1.02 0.923 – 1.13 0.711 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.956 0.855 – 1.07 0.435 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1 0.898 – 1.12 0.956 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 1 0.883 – 1.14 0.966 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 0.993 0.864 – 1.14 0.927 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.02 0.813 – 1.28 0.862 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.15 0.951 – 1.38 0.151 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.25 0.989 – 1.58 0.0615 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.1 0.906 – 1.34 0.331 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.947 0.858 – 1.04 0.275 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.872 0.757 – 1 0.0573 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.07 0.909 – 1.25 0.429 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.2 0.987 – 1.46 0.0672 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.924 0.848 – 1.01 0.0726 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.867 0.689 – 1.09 0.222 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.927 0.839 – 1.02 0.135 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.984 0.836 – 1.16 0.845 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.03 0.802 – 1.32 0.823 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.846 0.736 – 0.973 0.0187 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.886 0.717 – 1.09 0.261 96 959 all phecode
760 Back pain Symptoms 0.99 0.971 – 1.01 0.308 11126 111353 all phecode
761 Cervicalgia Symptoms 1.01 0.96 – 1.06 0.758 1791 17901 all phecode
764 Sciatica Symptoms 0.962 0.923 – 1 0.0742 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.03 0.969 – 1.09 0.359 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 0.993 0.915 – 1.08 0.86 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.955 0.89 – 1.02 0.193 870 8687 all phecode
771.1 Swelling of limb Symptoms 0.988 0.958 – 1.02 0.417 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 1.02 0.941 – 1.1 0.649 659 6581 all phecode
773 Pain in limb Symptoms 0.992 0.966 – 1.02 0.535 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 0.928 0.797 – 1.08 0.335 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.948 0.904 – 0.994 0.026 1870 18715 all phecode
782.3 Edema Symptoms 1.01 0.964 – 1.07 0.589 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 1.04 0.895 – 1.21 0.597 175 1748 all phecode
783 Fever of unknown origin Symptoms 1.01 0.977 – 1.04 0.563 3911 39105 all phecode
785 Abdominal pain Symptoms 0.982 0.972 – 0.992 0.000727 40080 301686 all phecode
788 Syncope and collapse Symptoms 0.979 0.958 – 1 0.0573 9069 90813 all phecode
789 Nausea and vomiting Symptoms 0.991 0.972 – 1.01 0.357 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 0.934 0.789 – 1.1 0.423 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 1.02 0.824 – 1.27 0.835 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 0.98 0.955 – 1.01 0.114 6357 63635 all phecode
791 Gangrene Symptoms 1.05 0.961 – 1.14 0.284 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.956 0.777 – 1.18 0.67 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.888 0.747 – 1.06 0.18 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 0.981 0.9 – 1.07 0.671 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1 0.835 – 1.21 0.97 120 1198 all phecode
797 Shock Symptoms 0.958 0.811 – 1.13 0.609 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 0.999 0.811 – 1.23 0.991 102 1020 all phecode
798 Malaise and fatigue Symptoms 0.969 0.935 – 1 0.0797 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 0.929 0.853 – 1.01 0.0896 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 1.04 1.01 – 1.06 0.00328 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.04 0.99 – 1.09 0.117 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.18 1 – 1.38 0.0448 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.01 0.969 – 1.06 0.569 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 1.01 0.939 – 1.09 0.77 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.991 0.948 – 1.04 0.682 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 1 0.956 – 1.05 0.91 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 1.1 1.02 – 1.19 0.0177 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 1.02 0.993 – 1.04 0.169 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 0.979 0.931 – 1.03 0.398 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.02 0.991 – 1.05 0.172 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.03 0.981 – 1.09 0.208 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.984 0.95 – 1.02 0.371 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1 0.951 – 1.06 0.865 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 1.05 0.977 – 1.13 0.174 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.03 0.97 – 1.09 0.37 1300 12998 all phecode
817 Concussion Injuries & Poisonings 1.05 0.916 – 1.2 0.496 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.968 0.885 – 1.06 0.482 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1 0.966 – 1.04 0.866 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 1.04 0.989 – 1.09 0.129 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 1 0.958 – 1.05 0.946 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 1 0.984 – 1.02 0.943 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 0.962 0.88 – 1.05 0.392 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 1.02 0.931 – 1.13 0.627 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1 0.975 – 1.03 0.859 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.05 0.887 – 1.23 0.595 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.02 0.926 – 1.11 0.742 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.953 0.909 – 0.999 0.0473 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.03 0.975 – 1.1 0.26 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.995 0.959 – 1.03 0.773 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.02 0.979 – 1.05 0.411 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 0.947 0.742 – 1.21 0.663 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.01 0.977 – 1.05 0.529 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.03 0.914 – 1.17 0.588 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.927 0.802 – 1.07 0.31 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.02 0.98 – 1.06 0.344 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.914 0.798 – 1.05 0.193 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 1.23 0.953 – 1.58 0.113 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 0.978 0.947 – 1.01 0.174 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.984 0.743 – 1.3 0.908 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.01 0.818 – 1.25 0.922 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.17 1.01 – 1.36 0.0406 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 1.01 0.917 – 1.1 0.887 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 0.933 0.812 – 1.07 0.323 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 0.966 0.826 – 1.13 0.666 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.09 0.923 – 1.28 0.313 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 0.964 0.911 – 1.02 0.198 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 0.993 0.963 – 1.03 0.678 4260 42663 all phecode
916 Contusion Injuries & Poisonings 1.07 1.02 – 1.13 0.0105 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.973 0.834 – 1.13 0.723 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.04 0.938 – 1.16 0.45 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 1.1 0.97 – 1.25 0.137 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.997 0.953 – 1.04 0.882 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.965 0.845 – 1.1 0.602 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.04 0.85 – 1.27 0.705 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.01 0.927 – 1.11 0.778 550 5509 all phecode
947 Urticaria Injuries & Poisonings 0.953 0.855 – 1.06 0.381 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 0.902 0.814 – 1 0.0495 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.01 0.917 – 1.12 0.806 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.933 0.823 – 1.06 0.275 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.996 0.908 – 1.09 0.925 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 0.926 0.711 – 1.21 0.569 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.05 0.819 – 1.34 0.707 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.98 0.965 – 0.995 0.00834 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.983 0.967 – 0.999 0.0369 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.05 0.952 – 1.16 0.319 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.03 0.959 – 1.1 0.448 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.991 0.891 – 1.1 0.86 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 0.979 0.879 – 1.09 0.691 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.04 0.911 – 1.2 0.535 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.992 0.877 – 1.12 0.901 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.976 0.863 – 1.1 0.705 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.978 0.953 – 1 0.102 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.953 0.897 – 1.01 0.119 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.02 0.928 – 1.12 0.682 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.02 0.916 – 1.13 0.748 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.927 0.847 – 1.02 0.103 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.02 0.938 – 1.11 0.625 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.04 0.994 – 1.09 0.0872 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.11 0.959 – 1.29 0.158 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.04 0.918 – 1.18 0.538 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.06 0.85 – 1.31 0.624 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.1 0.903 – 1.34 0.346 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.14 0.931 – 1.4 0.202 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.22 0.943 – 1.57 0.131 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.2 0.932 – 1.55 0.157 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.04 0.914 – 1.19 0.527 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 0.979 0.907 – 1.06 0.592 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.925 0.8 – 1.07 0.288 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.13 0.858 – 1.48 0.394 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 0.854 0.701 – 1.04 0.115 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.929 0.763 – 1.13 0.458 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.04 0.832 – 1.3 0.726 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 0.964 0.93 – 1 0.0546 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 0.978 0.943 – 1.02 0.254 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 0.978 0.943 – 1.02 0.254 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 0.962 0.916 – 1.01 0.134 1682 19027 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.01 0.921 – 1.11 0.846 500 5799 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.891 0.738 – 1.08 0.227 117 1343 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 0.919 0.785 – 1.08 0.295 171 1766 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.13 0.542 – 2.8 0.746 6 74 exclusion phecode
010 Tuberculosis Infectious Diseases 0.89 0.579 – 1.38 0.585 23 263 exclusion phecode
038 Septicemia Infectious Diseases 1 0.928 – 1.08 0.975 725 7408 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 0.962 0.803 – 1.15 0.67 134 1367 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.01 0.791 – 1.29 0.934 67 665 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 0.994 0.95 – 1.04 0.8 2031 22897 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 0.93 0.844 – 1.02 0.142 444 4933 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 0.984 0.861 – 1.12 0.807 233 2545 exclusion phecode
041.4 E. coli Infectious Diseases 1 0.92 – 1.1 0.934 551 6795 exclusion phecode
053 Herpes zoster Infectious Diseases 1.04 0.822 – 1.33 0.718 70 930 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.05 0.632 – 1.73 0.839 15 193 exclusion phecode
054 Herpes simplex Infectious Diseases 0.755 0.536 – 1.06 0.0973 43 375 exclusion phecode
070 Viral hepatitis Infectious Diseases 0.862 0.684 – 1.08 0.2 83 763 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.03 0.562 – 1.93 0.924 15 129 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.715 0.365 – 1.38 0.285 9 124 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 0.965 0.657 – 1.43 0.852 27 253 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.05 0.843 – 1.32 0.641 78 740 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.09 0.834 – 1.44 0.517 57 820 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.11 0.3 – 3.05 0.963 1 5 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.21 1.21 – 1.22 0.879 1 6 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.913 0.791 – 1.05 0.215 193 2034 exclusion phecode
079 Viral infection Infectious Diseases 1.05 0.963 – 1.15 0.262 549 5600 exclusion phecode
079.1 Varicella infection Infectious Diseases 1.03 0.562 – 1.9 0.931 9 70 exclusion phecode
080 Postoperative infection Infectious Diseases 0.979 0.908 – 1.06 0.59 713 8584 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.09 0.984 – 1.21 0.0981 412 4337 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.43 0.745 – 1.5 0.22 8 90 exclusion phecode
1000 Burns Injuries & Poisonings 1.41 1.08 – 1.85 0.0117 60 687 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 0.923 0.789 – 1.08 0.312 171 1834 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.07 1 – 1.13 0.0453 1074 11906 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.15 0.824 – 1.61 0.407 41 462 exclusion phecode
1005 Other symptoms Injuries & Poisonings 0.931 0.824 – 1.05 0.25 285 2857 exclusion phecode
1006 Crushing injury Injuries & Poisonings 0.884 0.541 – 1.45 0.613 20 179 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 0.955 0.636 – 1.43 0.817 26 247 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.05 0.858 – 1.29 0.63 98 971 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 1.01 0.953 – 1.08 0.666 1066 11800 exclusion phecode
1010 Other tests Injuries & Poisonings 0.978 0.92 – 1.04 0.467 1121 12749 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.04 0.986 – 1.09 0.16 1598 18370 exclusion phecode
1012 Late effect Injuries & Poisonings 0.97 0.568 – 1.64 0.907 20 190 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 0.986 0.697 – 1.39 0.936 41 467 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.752 0.261 – 2.36 0.574 5 55 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 1.03 0.949 – 1.11 0.526 682 8113 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.01 0.97 – 1.05 0.687 2825 31585 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.07 0.729 – 1.57 0.729 29 345 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 1.06 0.72 – 1.57 0.763 28 334 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.935 0.465 – 1.79 0.832 8 98 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.42 0.829 – 2.55 0.202 13 139 exclusion phecode
112 Candidiasis Infectious Diseases 1.03 0.929 – 1.14 0.597 417 4523 exclusion phecode
117 Mycoses Infectious Diseases 1.12 0.854 – 1.48 0.402 54 531 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.09 0.791 – 1.51 0.59 36 334 exclusion phecode
130 Spirochetal infection Infectious Diseases 1.4 0.756 – 2.71 0.274 13 120 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 0.655 0.6 – 1.11 0.136 8 95 exclusion phecode
134 Helminthiases Infectious Diseases 1.02 0.699 – 1.47 0.934 30 242 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 0.876 0.562 – 1.35 0.54 22 193 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.98 0.687 – 1.4 0.908 34 340 exclusion phecode
145 Cancer of mouth Neoplasms 1.07 0.875 – 1.3 0.519 109 999 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.1 0.817 – 1.49 0.523 45 372 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.917 0.598 – 1.4 0.681 24 202 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 0.982 0.921 – 1.1 0.951 8 61 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.04 0.792 – 1.37 0.768 59 595 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.03 0.671 – 1.57 0.9 22 224 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.12 0.636 – 1.96 0.693 15 129 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 0.779 0.398 – 1.42 0.41 11 122 exclusion phecode
150 Cancer of esophagus Neoplasms 0.926 0.725 – 1.18 0.531 82 756 exclusion phecode
151 Cancer of stomach Neoplasms 1.01 0.781 – 1.3 0.959 69 669 exclusion phecode
153 Colorectal cancer Neoplasms 0.99 0.922 – 1.06 0.774 820 8014 exclusion phecode
153.2 Colon cancer Neoplasms 0.963 0.885 – 1.05 0.388 570 5587 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.02 0.913 – 1.13 0.772 361 3548 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.13 0.881 – 1.44 0.337 73 703 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.54 0.947 – 2.55 0.0756 18 220 exclusion phecode
157 Pancreatic cancer Neoplasms 0.962 0.794 – 1.17 0.689 115 1244 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.964 0.827 – 1.12 0.638 187 1988 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.04 0.971 – 1.1 0.286 1008 10196 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.32 0.929 – 1.89 0.121 41 326 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.982 0.735 – 1.32 0.9 53 421 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.09 0.832 – 1.42 0.538 57 669 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 1.16 0.57 – 2.49 0.663 7 107 exclusion phecode
165 Cancer within the respiratory system Neoplasms 0.974 0.887 – 1.07 0.59 467 5048 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 0.944 0.853 – 1.04 0.262 406 4311 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 0.834 0.636 – 1.09 0.181 58 750 exclusion phecode
170.1 Bone cancer Neoplasms 0.709 0.418 – 1.19 0.172 14 189 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 0.89 0.663 – 1.19 0.425 47 613 exclusion phecode
172 Skin cancer Neoplasms 1.01 0.97 – 1.05 0.651 2640 26609 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.01 0.925 – 1.1 0.825 530 5557 exclusion phecode
172.11 Melanomas of skin Neoplasms 1.01 0.926 – 1.1 0.812 539 5650 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1 0.961 – 1.05 0.836 2128 21283 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 1.03 0.866 – 1.23 0.742 140 1383 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.15 0.784 – 1.69 0.466 32 387 exclusion phecode
174 Breast cancer Neoplasms 0.988 0.961 – 1.02 0.427 5158 49314 exclusion phecode
174.1 Breast cancer [female] Neoplasms 0.987 0.96 – 1.02 0.39 5130 49021 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.983 0.955 – 1.01 0.263 4830 46312 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.21 0.855 – 1.73 0.271 38 438 exclusion phecode
175 Acquired absence of breast Neoplasms 1.06 0.987 – 1.13 0.112 902 9118 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.04 0.954 – 1.13 0.401 612 6319 exclusion phecode
180.1 Cervical cancer Neoplasms 0.93 0.727 – 1.19 0.559 71 927 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.05 0.968 – 1.15 0.23 587 6064 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 1 0.922 – 1.09 0.934 577 5346 exclusion phecode
184 Cancer of other female genital organs Neoplasms 0.952 0.867 – 1.05 0.301 486 5412 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.965 0.864 – 1.08 0.525 351 3892 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.948 0.847 – 1.06 0.35 341 3775 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.997 0.819 – 1.21 0.975 100 1201 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.99 0.899 – 1.09 0.845 424 4865 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.914 0.759 – 1.1 0.342 122 1512 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.932 0.771 – 1.13 0.464 116 1443 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.814 0.397 – 1.64 0.548 10 108 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.01 0.884 – 1.14 0.933 241 2547 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.989 0.86 – 1.14 0.879 207 2188 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.675 0.421 – 1.05 0.0829 16 167 exclusion phecode
190 Cancer of eye Neoplasms 0.943 0.647 – 1.37 0.751 33 379 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.09 0.886 – 1.34 0.42 100 1093 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 1.15 0.913 – 1.45 0.232 81 901 exclusion phecode
191.11 Cancer of brain Neoplasms 1.12 0.882 – 1.42 0.351 76 811 exclusion phecode
193 Thyroid cancer Neoplasms 1.19 0.942 – 1.5 0.144 79 905 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 0.815 0.475 – 1.36 0.423 14 164 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.02 0.985 – 1.06 0.232 2903 31852 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.02 0.985 – 1.07 0.223 2775 30410 exclusion phecode
197 Chemotherapy Neoplasms 0.995 0.966 – 1.03 0.738 4735 49725 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.02 0.974 – 1.06 0.445 2195 21920 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.04 0.981 – 1.1 0.201 1377 13575 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.992 0.902 – 1.09 0.874 480 4827 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.01 0.913 – 1.12 0.82 396 4020 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1 0.914 – 1.1 0.984 524 5348 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.03 0.89 – 1.2 0.661 185 1873 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.04 0.938 – 1.15 0.462 417 4036 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.29 0.904 – 1.85 0.154 32 356 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.01 0.88 – 1.15 0.931 227 2589 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.7 0.973 – 3.06 0.0537 13 177 exclusion phecode
200 Myeloproliferative disease Neoplasms 0.923 0.781 – 1.09 0.345 146 1670 exclusion phecode
200.1 Polycythemia vera Neoplasms 0.564 0.383 – 0.815 0.00216 29 444 exclusion phecode
201 Hodgkin's disease Neoplasms 0.725 0.503 – 1.04 0.0741 31 363 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.983 0.883 – 1.09 0.751 366 3904 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.991 0.882 – 1.11 0.875 311 3167 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.12 0.874 – 1.44 0.358 67 699 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.03 0.836 – 1.28 0.765 98 998 exclusion phecode
204 Leukemia Neoplasms 1.15 1.01 – 1.31 0.0354 260 2686 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1.31 1.02 – 1.67 0.0312 76 848 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.39 0.707 – 2.98 0.329 9 92 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.26 0.973 – 1.65 0.078 65 727 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.01 0.792 – 1.28 0.965 77 813 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 1.1 0.829 – 1.46 0.508 59 549 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.928 0.617 – 1.39 0.71 25 264 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.23 0.983 – 1.53 0.07 91 913 exclusion phecode
208 Benign neoplasm of colon Neoplasms 0.977 0.942 – 1.01 0.22 3133 35049 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.926 0.801 – 1.07 0.3 190 2053 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.991 0.935 – 1.05 0.759 1220 13266 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.873 0.643 – 1.19 0.373 44 516 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.18 0.883 – 1.57 0.261 55 656 exclusion phecode
214 Lipoma Neoplasms 1.04 0.975 – 1.12 0.221 922 10710 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.04 0.964 – 1.12 0.323 754 8783 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.02 0.893 – 1.17 0.744 229 2492 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.944 0.896 – 0.995 0.0322 1516 16556 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.08 0.908 – 1.3 0.374 132 1358 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 1.13 0.933 – 1.37 0.214 121 1300 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 1.02 0.975 – 1.06 0.462 2523 35009 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 1.02 0.978 – 1.06 0.385 2543 36078 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.01 0.833 – 1.21 0.953 117 1371 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 1.05 0.953 – 1.15 0.335 453 5269 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.962 0.731 – 1.27 0.776 53 757 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.54 0.977 – 2.5 0.0595 22 238 exclusion phecode
224 Benign neoplasm of eye Neoplasms 1.3 0.881 – 1.92 0.18 27 277 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.3 0.735 – 2.35 0.338 13 170 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.15 0.995 – 1.33 0.058 201 2016 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.18 1.02 – 1.37 0.0288 190 1876 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.04 0.608 – 1.83 0.869 15 197 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.01 0.776 – 1.32 0.935 55 776 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.96 0.833 – 1.11 0.57 200 2135 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.987 0.702 – 1.39 0.937 34 375 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.06 0.878 – 1.29 0.532 118 1218 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.781 0.587 – 1.03 0.081 51 554 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.962 0.854 – 1.08 0.525 293 3274 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.973 0.886 – 1.07 0.557 498 5609 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.19 1.01 – 1.42 0.0392 146 1855 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.954 0.851 – 1.07 0.419 330 3583 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.873 0.724 – 1.05 0.15 122 1470 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.99 0.861 – 1.14 0.886 221 2239 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.01 0.917 – 1.11 0.893 488 5451 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 1.05 0.87 – 1.26 0.63 130 1283 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.17 0.745 – 1.84 0.482 23 305 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 1.11 0.806 – 1.54 0.506 41 412 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 0.978 0.948 – 1.01 0.17 4173 46923 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.974 0.867 – 1.1 0.66 317 3684 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.01 0.707 – 1.44 0.969 30 283 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.976 0.945 – 1.01 0.144 3977 45001 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.873 0.691 – 1.1 0.248 77 1006 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.771 0.595 – 0.998 0.0454 64 772 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.827 0.642 – 1.06 0.134 65 748 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 0.994 0.816 – 1.21 0.952 108 1236 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 0.987 0.948 – 1.03 0.542 2503 30352 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.948 0.849 – 1.06 0.336 350 4217 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.13 0.792 – 1.64 0.493 31 401 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.63 0.794 – 3.5 0.174 10 96 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.913 0.713 – 1.17 0.463 67 801 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.06 0.687 – 1.66 0.771 22 230 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.993 0.951 – 1.04 0.739 2250 27623 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.854 0.486 – 1.52 0.555 11 187 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.939 0.595 – 1.49 0.781 20 222 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.927 0.768 – 1.12 0.425 112 1358 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.02 0.773 – 1.36 0.862 48 689 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 0.906 0.741 – 1.11 0.327 98 1081 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.15 0.817 – 1.64 0.419 33 352 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.787 0.611 – 1.01 0.0587 63 726 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.11 0.467 – 2.88 0.791 6 130 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.906 0.638 – 1.3 0.574 29 409 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.915 0.781 – 1.07 0.265 160 1890 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.13 0.942 – 1.37 0.182 117 1357 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.974 0.853 – 1.11 0.702 232 2643 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.943 0.821 – 1.09 0.413 212 2406 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.953 0.645 – 1.41 0.8 28 363 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.787 0.638 – 0.971 0.0234 83 1150 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.717 0.498 – 1.03 0.0641 32 352 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.64 0.398 – 1.02 0.055 21 200 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.681 0.615 – 1.09 0.0658 16 328 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.864 0.501 – 1.44 0.568 16 202 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.11 0.717 – 1.73 0.624 21 324 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.961 0.806 – 1.15 0.652 129 1467 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.01 0.724 – 1.41 0.96 35 424 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.1 0.732 – 1.69 0.622 22 289 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.763 0.448 – 1.28 0.288 14 157 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.01 0.792 – 1.28 0.957 69 831 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1 0.789 – 1.27 0.998 69 824 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.767 0.48 – 1.24 0.248 18 267 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.615 0.357 – 1.06 0.0634 14 232 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.9 0.554 – 1.48 0.66 13 184 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.956 0.663 – 1.38 0.801 29 351 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.849 0.603 – 1.2 0.337 35 358 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.2 1.13 – 1.23 0.737 1 48 exclusion phecode
260.6 Anorexia Endocrine/metabolic 0.998 0.86 – 1.16 0.981 186 1755 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 0.963 0.846 – 1.1 0.564 243 2730 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.986 0.83 – 1.17 0.876 138 1615 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.997 0.822 – 1.21 0.975 109 1162 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.759 0.465 – 1.22 0.242 18 236 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.09 0.815 – 1.46 0.563 51 593 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.22 0.86 – 1.73 0.263 38 462 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.04 0.754 – 1.43 0.821 43 512 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.904 0.643 – 1.27 0.552 38 454 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 0.673 0.425 – 1.05 0.073 24 325 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 0.787 0.51 – 1.23 0.265 20 244 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.74 0.999 – 3.62 0.0633 13 131 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.32 0.903 – 1.94 0.139 29 399 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.13 0.754 – 1.7 0.537 26 359 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.989 0.961 – 1.02 0.48 4907 48027 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.989 0.961 – 1.02 0.478 4899 47963 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.985 0.956 – 1.02 0.333 4555 46146 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.15 1.02 – 1.31 0.709 6 65 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.13 0.732 – 1.77 0.558 23 257 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.939 0.628 – 1.42 0.749 24 376 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.929 0.808 – 1.07 0.295 214 2546 exclusion phecode
274.1 Gout Endocrine/metabolic 0.904 0.76 – 1.07 0.247 140 1641 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.89 0.847 – 0.936 0.756 3 35 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.956 0.757 – 1.21 0.706 75 953 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.942 0.74 – 1.2 0.623 71 901 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.977 0.869 – 1.1 0.701 324 3580 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.875 0.687 – 1.11 0.275 79 767 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.19 0.877 – 1.61 0.261 49 685 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.955 0.825 – 1.11 0.542 210 2320 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.738 0.438 – 1.22 0.22 21 258 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1 0.947 – 1.06 0.933 1284 13708 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 0.982 0.912 – 1.06 0.639 751 8010 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.95 0.57 – 1.5 0.791 26 311 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 0.912 0.822 – 1.01 0.0792 380 3927 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.15 0.964 – 1.38 0.118 130 1343 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.04 0.915 – 1.17 0.582 276 3226 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.02 0.876 – 1.18 0.81 175 1904 exclusion phecode
276.41 Acidosis Endocrine/metabolic 0.974 0.829 – 1.15 0.752 150 1727 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.32 0.872 – 2.02 0.182 24 186 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.03 0.939 – 1.13 0.535 494 5294 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.21 0.955 – 1.55 0.11 72 715 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 0.92 0.615 – 1.39 0.678 24 293 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.09 0.926 – 1.28 0.305 163 1902 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.943 0.685 – 1.3 0.714 41 375 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.34 0.912 – 1.99 0.132 29 361 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.903 0.858 – 2.59 0.773 7 67 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1 0.957 – 1.06 0.854 1739 22150 exclusion phecode
278.1 Obesity Endocrine/metabolic 1 0.953 – 1.05 0.975 1704 21750 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 0.625 0.314 – 1.13 0.107 12 201 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.23 0.703 – 2.33 0.444 14 183 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.967 0.715 – 1.31 0.827 44 470 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1 0.711 – 1.42 0.985 35 398 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.978 0.905 – 1.61 0.901 25 306 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.11 0.648 – 1.88 0.692 20 181 exclusion phecode
280 Iron deficiency anemias Hematopoietic 0.952 0.902 – 1 0.0685 1476 16868 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.955 0.905 – 1.01 0.0965 1442 16191 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.954 0.751 – 1.22 0.696 70 1049 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.03 0.899 – 1.18 0.675 226 2696 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.05 0.912 – 1.2 0.523 222 2596 exclusion phecode
281.11 Pernicious anemia Hematopoietic 0.976 0.832 – 1.15 0.76 166 2005 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.36 0.928 – 2.03 0.111 28 397 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 0.997 0.692 – 1.43 0.988 32 320 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.18 0.5 – 2.89 0.664 6 127 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.13 0.78 – 1.67 0.507 28 275 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.36 0.69 – 3.01 0.382 9 86 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.02 0.648 – 1.64 0.928 18 177 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.17 0.794 – 1.75 0.412 25 316 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.06 0.661 – 1.71 0.796 18 233 exclusion phecode
284 Aplastic anemia Hematopoietic 0.864 0.663 – 1.13 0.274 64 645 exclusion phecode
285 Other anemias Hematopoietic 1.01 0.971 – 1.06 0.549 2346 26300 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.928 0.677 – 1.27 0.634 41 549 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 0.943 0.796 – 1.12 0.5 139 1506 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.85 0.686 – 1.05 0.134 92 926 exclusion phecode
286 Coagulation defects Hematopoietic 0.92 0.782 – 1.08 0.309 150 1781 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.903 0.729 – 1.12 0.346 89 994 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.676 0.428 – 1.05 0.0757 21 237 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.953 0.739 – 1.23 0.706 63 654 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.18 0.488 – 3.65 0.667 3 118 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.717 0.392 – 1.29 0.251 14 137 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.992 0.753 – 1.31 0.955 52 711 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.11 0.983 – 1.26 0.0908 278 2773 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.39 0.916 – 2.14 0.119 25 256 exclusion phecode
287.2 Allergic purpura Hematopoietic 1.12 0.579 – 2.35 0.731 9 73 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.11 0.981 – 1.26 0.0963 259 2634 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.15 0.917 – 1.44 0.228 83 878 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.13 0.592 – 2.16 0.688 11 136 exclusion phecode
288 Diseases of white blood cells Hematopoietic 0.981 0.915 – 1.05 0.6 867 8476 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1 0.931 – 1.08 0.917 751 7258 exclusion phecode
288.11 Neutropenia Hematopoietic 1.01 0.934 – 1.09 0.861 752 7275 exclusion phecode
288.3 Eosinophilia Hematopoietic 0.71 0.335 – 1.29 0.258 11 116 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.07 0.914 – 1.26 0.384 162 1696 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.21 0.935 – 1.58 0.143 66 686 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1 0.912 – 1.1 0.945 467 4971 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1.03 0.823 – 1.3 0.77 81 964 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 0.852 0.573 – 1.27 0.408 24 316 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 0.897 0.497 – 1.63 0.704 12 144 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.07 0.952 – 1.21 0.25 295 3392 exclusion phecode
290.1 Dementias Mental Disorders 1.05 0.894 – 1.24 0.542 149 1892 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 1.07 0.842 – 1.37 0.569 65 939 exclusion phecode
290.16 Vascular dementia Mental Disorders 1.15 0.795 – 1.68 0.458 27 254 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.04 0.837 – 1.3 0.716 90 908 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.39 0.468 – 4.43 0.496 4 59 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.985 0.814 – 1.19 0.879 113 1380 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.783 0.445 – 1.19 0.227 25 230 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.1 0.794 – 1.53 0.562 36 465 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 0.994 0.752 – 1.32 0.965 52 724 exclusion phecode
292 Neurological disorders Mental Disorders 0.955 0.883 – 1.03 0.24 688 7732 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.982 0.86 – 1.12 0.786 225 2577 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 1.08 0.727 – 1.62 0.707 26 305 exclusion phecode
292.3 Memory loss Mental Disorders 0.893 0.726 – 1.1 0.277 98 1180 exclusion phecode
292.4 Altered mental status Mental Disorders 0.93 0.83 – 1.04 0.209 322 3554 exclusion phecode
292.6 Hallucinations Mental Disorders 0.686 0.522 – 0.898 0.00579 56 530 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 0.861 0.744 – 0.995 0.0419 197 2122 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.979 0.833 – 1.15 0.796 158 1699 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.03 0.854 – 1.24 0.769 116 1187 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.19 0.941 – 1.52 0.143 74 712 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.09 0.749 – 1.61 0.648 26 312 exclusion phecode
295.3 Psychosis Mental Disorders 0.673 0.413 – 0.952 0.0288 28 282 exclusion phecode
296 Mood disorders Mental Disorders 1.01 0.967 – 1.05 0.667 2265 26930 exclusion phecode
296.1 Bipolar Mental Disorders 0.974 0.842 – 1.13 0.719 197 2072 exclusion phecode
296.2 Depression Mental Disorders 1.01 0.968 – 1.06 0.602 2146 25774 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.28 0.981 – 1.69 0.068 64 783 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.1 0.809 – 1.51 0.538 44 602 exclusion phecode
300 Anxiety disorders Mental Disorders 0.986 0.933 – 1.04 0.627 1353 15455 exclusion phecode
300.1 Anxiety disorder Mental Disorders 0.976 0.922 – 1.03 0.405 1299 14613 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 1.22 0.827 – 1.85 0.31 31 290 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.937 0.792 – 1.11 0.438 150 1634 exclusion phecode
300.13 Phobia Mental Disorders 0.927 0.757 – 1.13 0.456 107 1293 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.13 0.712 – 1.84 0.588 19 223 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.09 0.406 – 3.37 0.814 3 83 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.04 0.571 – 1.91 0.9 12 181 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.991 0.571 – 1.81 0.973 9 137 exclusion phecode
301 Personality disorders Mental Disorders 0.973 0.7 – 1.36 0.866 37 512 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.12 0.666 – 1.9 0.665 14 170 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 0.794 0.758 – 2.22 0.531 3 60 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.989 0.796 – 1.23 0.921 87 1087 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.978 0.762 – 1.26 0.861 68 830 exclusion phecode
303.4 Somatoform disorder Mental Disorders 1.02 0.661 – 1.57 0.922 19 276 exclusion phecode
304 Adjustment reaction Mental Disorders 1.15 0.851 – 1.56 0.359 49 517 exclusion phecode
305.2 Eating disorder Mental Disorders 1.29 1.2 – 1.44 0.262 15 198 exclusion phecode
306 Other mental disorder Mental Disorders 0.993 0.962 – 1.03 0.659 4097 44263 exclusion phecode
306.9 Tension headache Mental Disorders 0.898 0.68 – 1.18 0.44 58 752 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.9 0.788 – 0.958 0.766 5 93 exclusion phecode
313.3 Autism Mental Disorders 1.18 0.332 – 4.97 0.746 3 49 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.11 0.824 – 1.5 0.481 47 508 exclusion phecode
315.1 Learning disorder Mental Disorders 1.38 0.635 – 3.19 0.356 6 159 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.621 0.301 – 1.23 0.151 11 140 exclusion phecode
316 Substance addiction and disorders Mental Disorders 0.99 0.894 – 1.1 0.847 408 4492 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.21 0.697 – 2.17 0.492 13 108 exclusion phecode
317 Alcohol-related disorders Mental Disorders 0.999 0.945 – 1.06 0.965 1364 15351 exclusion phecode
317.1 Alcoholism Mental Disorders 1.01 0.948 – 1.08 0.742 1017 11349 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 0.895 0.681 – 1.17 0.414 56 615 exclusion phecode
318 Tobacco use disorder Mental Disorders 1 0.963 – 1.05 0.866 2515 28241 exclusion phecode
320 Meningitis Neurological 1.04 0.808 – 1.34 0.767 71 752 exclusion phecode
323 Encephalitis Neurological 1.04 0.812 – 1.33 0.761 71 625 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 0.702 0.381 – 1.27 0.229 15 153 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.02 0.773 – 1.35 0.872 52 595 exclusion phecode
327 Sleep disorders Neurological 1.07 0.895 – 1.28 0.46 142 1376 exclusion phecode
327.3 Sleep apnea Neurological 1.03 0.933 – 1.14 0.543 402 4412 exclusion phecode
327.4 Insomnia Neurological 1.51 1.01 – 2.5 0.0528 23 315 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.61 1.06 – 3.01 0.0343 22 266 exclusion phecode
331 Other cerebral degenerations Neurological 1.02 0.872 – 1.19 0.821 176 1977 exclusion phecode
331.1 Hydrocephalus Neurological 1.07 0.867 – 1.32 0.534 97 1037 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 0.869 0.648 – 1.17 0.337 49 602 exclusion phecode
332 Parkinson's disease Neurological 1.05 0.904 – 1.22 0.517 193 1925 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.04 0.885 – 1.22 0.642 169 1946 exclusion phecode
333.1 Essential tremor Neurological 0.956 0.69 – 1.33 0.781 39 471 exclusion phecode
333.2 Myoclonus Neurological 0.993 0.61 – 1.6 0.976 17 142 exclusion phecode
333.4 Torsion dystonia Neurological 0.996 0.746 – 1.33 0.978 53 579 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.05 0.925 – 1.2 0.445 261 2929 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.81 1.14 – 2.99 0.0126 21 193 exclusion phecode
334.2 Anterior horn cell disease Neurological 1.06 0.786 – 1.43 0.705 46 396 exclusion phecode
335 Multiple sclerosis Neurological 1 0.895 – 1.13 0.95 324 3301 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 0.819 0.59 – 1.14 0.223 35 435 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.07 0.517 – 2.18 0.833 9 110 exclusion phecode
338 Pain Neurological 1.09 0.911 – 1.31 0.339 124 1638 exclusion phecode
338.1 Acute pain Neurological 1.06 0.832 – 1.36 0.621 73 784 exclusion phecode
338.2 Chronic pain Neurological 1.18 0.901 – 1.55 0.222 52 830 exclusion phecode
339 Other headache syndromes Neurological 0.984 0.931 – 1.04 0.557 1392 16659 exclusion phecode
340 Migraine Neurological 0.933 0.858 – 1.01 0.101 611 7153 exclusion phecode
340.1 Migrain with aura Neurological 1.08 0.739 – 1.58 0.699 34 423 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.989 0.718 – 1.36 0.947 41 528 exclusion phecode
342 Hemiplegia Neurological 1.03 0.898 – 1.19 0.638 198 2477 exclusion phecode
343 Infantile cerebral palsy Neurological 0.899 0.549 – 1.47 0.657 18 199 exclusion phecode
344 Other paralytic syndromes Neurological 0.801 0.65 – 0.986 0.0346 96 998 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.965 0.896 – 1.04 0.336 764 8526 exclusion phecode
345.1 Epilepsy Neurological 0.762 0.633 – 0.917 0.00376 114 1399 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 0.705 0.528 – 0.94 0.0155 49 680 exclusion phecode
345.12 Partial epilepsy Neurological 0.808 0.607 – 1.08 0.14 44 478 exclusion phecode
345.3 Convulsions Neurological 0.929 0.828 – 1.04 0.212 313 3462 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.982 0.674 – 1.43 0.924 30 291 exclusion phecode
348 Other conditions of brain Neurological 1 0.838 – 1.2 0.973 124 1278 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.02 0.767 – 1.37 0.876 49 540 exclusion phecode
348.4 Cerebral cysts Neurological 0.87 0.575 – 1.32 0.496 24 246 exclusion phecode
348.7 Coma Neurological 1.31 0.971 – 1.77 0.0746 51 585 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.15 0.825 – 1.62 0.395 35 357 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 0.968 0.723 – 1.3 0.822 52 659 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.907 0.683 – 1.21 0.495 52 611 exclusion phecode
350 Abnormal movement Neurological 1.13 1.02 – 1.25 0.0159 411 4789 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.21 1.01 – 1.44 0.0377 134 1585 exclusion phecode
350.2 Abnormality of gait Neurological 1.07 0.944 – 1.22 0.288 251 2980 exclusion phecode
350.3 Lack of coordination Neurological 1.07 0.816 – 1.4 0.629 51 538 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.765 0.394 – 1.47 0.397 9 98 exclusion phecode
351 Other peripheral nerve disorders Neurological 0.975 0.938 – 1.01 0.184 2872 32964 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.05 0.919 – 1.19 0.498 254 2873 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.18 0.96 – 1.45 0.114 103 1115 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 0.916 0.772 – 1.09 0.313 144 1677 exclusion phecode
353 Nerve root and plexus disorders Neurological 0.994 0.863 – 1.15 0.937 207 2473 exclusion phecode
353.1 Nerve plexus lesions Neurological 1.43 0.96 – 2.16 0.0766 26 236 exclusion phecode
353.2 Nerve root lesions Neurological 1.97 1.04 – 4.12 0.0396 12 120 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.27 0.754 – 2.16 0.351 17 221 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 0.974 0.833 – 1.14 0.737 171 2042 exclusion phecode
358 Myoneural disorders Neurological 0.855 0.613 – 1.19 0.342 36 421 exclusion phecode
358.1 Myasthenia gravis Neurological 0.798 0.563 – 1.13 0.189 34 390 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 1.32 1.05 – 1.67 0.0189 82 849 exclusion phecode
359.1 Muscular dystrophies Neurological 0.972 0.577 – 1.68 0.911 15 180 exclusion phecode
359.2 Myopathy Neurological 1.33 1.03 – 1.72 0.0264 70 695 exclusion phecode
360 Disorders of the globe Sense Organs 1 0.777 – 1.3 0.989 61 732 exclusion phecode
360.2 Progressive myopia Sense Organs 0.979 0.74 – 1.3 0.881 48 598 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.945 0.864 – 1.03 0.223 515 5307 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.946 0.823 – 1.09 0.438 206 2103 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.93 0.85 – 1.09 0.805 8 114 exclusion phecode
362 Other retinal disorders Sense Organs 0.926 0.862 – 0.995 0.0346 810 8681 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.938 0.859 – 1.03 0.158 532 5722 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.939 0.859 – 1.03 0.161 531 5707 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.05 0.733 – 1.51 0.773 31 275 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1.01 0.643 – 1.57 0.979 20 189 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.915 0.775 – 1.08 0.292 144 1512 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 1.22 0.808 – 1.89 0.333 25 305 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.04 0.614 – 1.73 0.884 15 160 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.05 0.663 – 1.69 0.837 23 213 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.971 0.685 – 1.38 0.867 38 391 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.995 0.522 – 1.91 0.988 14 157 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.07 0.903 – 1.27 0.427 151 1454 exclusion phecode
364.1 Corneal opacity Sense Organs 0.468 0.228 – 0.892 0.0186 12 155 exclusion phecode
364.2 Corneal edema Sense Organs 1.06 0.634 – 1.78 0.825 16 155 exclusion phecode
364.4 Corneal degenerations Sense Organs 1.12 0.821 – 1.54 0.462 46 382 exclusion phecode
364.41 Keratoconus Sense Organs 0.752 0.364 – 1.52 0.406 11 90 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.816 0.597 – 1.11 0.188 50 510 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.69 0.45 – 1.05 0.0759 22 205 exclusion phecode
365 Glaucoma Sense Organs 0.922 0.859 – 0.989 0.0238 838 9160 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 1.02 0.876 – 1.18 0.839 188 1964 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 1.01 0.875 – 1.18 0.848 187 1962 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.884 0.762 – 1.02 0.1 190 1873 exclusion phecode
366 Cataract Sense Organs 0.955 0.925 – 0.985 0.00318 4515 38337 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.938 0.54 – 1.64 0.813 14 168 exclusion phecode
366.2 Senile cataract Sense Organs 0.918 0.876 – 0.962 0.000337 1905 19770 exclusion phecode
366.3 Traumatic cataract Sense Organs 0.942 0.449 – 1.97 0.864 6 74 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.958 0.876 – 1.05 0.354 521 5221 exclusion phecode
367.1 Myopia Sense Organs 0.936 0.831 – 1.06 0.279 297 2830 exclusion phecode
367.2 Astigmatism Sense Organs 0.875 0.642 – 1.19 0.389 47 441 exclusion phecode
367.8 Hypermetropia Sense Organs 0.892 0.696 – 1.14 0.359 63 668 exclusion phecode
367.9 Blindness and low vision Sense Organs 0.959 0.784 – 1.17 0.683 111 1331 exclusion phecode
368 Visual disturbances Sense Organs 0.961 0.877 – 1.05 0.389 497 5934 exclusion phecode
368.1 Amblyopia Sense Organs 0.99 0.824 – 1.19 0.913 120 1250 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.05 0.873 – 1.26 0.614 126 1261 exclusion phecode
368.3 Anisometropia Sense Organs 0.87 0.586 – 1.29 0.471 23 322 exclusion phecode
368.4 Visual field defects Sense Organs 0.806 0.612 – 1.06 0.12 55 543 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 1.02 0.818 – 1.26 0.881 95 1267 exclusion phecode
369 Infection of the eye Sense Organs 1.2 0.986 – 1.47 0.0672 108 1163 exclusion phecode
369.2 Eye infection, viral Sense Organs 1.73 1.17 – 2.61 0.00663 30 264 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.968 0.712 – 1.32 0.834 42 416 exclusion phecode
370 Keratitis Sense Organs 0.954 0.748 – 1.22 0.699 71 685 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.756 0.527 – 1.08 0.118 35 316 exclusion phecode
371 Inflammation of the eye Sense Organs 1.01 0.927 – 1.1 0.825 577 5870 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.994 0.819 – 1.21 0.951 109 1000 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 1.04 0.939 – 1.15 0.47 426 4338 exclusion phecode
372 Disorders of conjunctiva Sense Organs 0.897 0.76 – 1.06 0.197 149 1609 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.97 0.914 – 1.03 0.313 1202 12922 exclusion phecode
374.1 Ectropion or entropion Sense Organs 1.06 0.911 – 1.25 0.431 169 1827 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 1.1 0.993 – 1.21 0.0689 435 4764 exclusion phecode
375 Disorders of lacrimal system Sense Organs 1.04 0.955 – 1.12 0.401 632 6135 exclusion phecode
375.2 Epiphora Sense Organs 1.01 0.887 – 1.16 0.853 234 2433 exclusion phecode
376 Disorders of the orbit Sense Organs 1.56 0.906 – 2.74 0.0977 15 188 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.951 0.753 – 1.2 0.668 71 840 exclusion phecode
377.1 Optic atrophy Sense Organs 0.479 0.225 – 0.915 0.0263 10 109 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.11 0.742 – 1.65 0.597 24 291 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.982 0.859 – 1.12 0.793 234 2600 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.894 0.757 – 1.06 0.182 154 1776 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.15 0.776 – 1.71 0.464 25 259 exclusion phecode
378.5 Paralytic strabismus Sense Organs 0.938 0.722 – 1.22 0.626 60 533 exclusion phecode
379 Other disorders of eye Sense Organs 0.975 0.904 – 1.05 0.512 741 8062 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.933 0.821 – 1.06 0.291 252 2905 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.01 0.906 – 1.12 0.925 377 4140 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.19 0.718 – 1.98 0.477 15 161 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.949 0.755 – 1.19 0.65 81 741 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.869 0.61 – 1.24 0.429 30 331 exclusion phecode
380 Disorders of external ear Sense Organs 1.08 0.88 – 1.34 0.448 96 1174 exclusion phecode
380.1 Otitis externa Sense Organs 0.971 0.764 – 1.24 0.811 71 923 exclusion phecode
380.4 Impacted cerumen Sense Organs 0.806 0.632 – 1.03 0.0778 70 753 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.04 0.937 – 1.16 0.452 374 4138 exclusion phecode
381.1 Otitis media Sense Organs 1.02 0.91 – 1.15 0.692 294 3351 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.06 0.891 – 1.26 0.507 136 1597 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.947 0.703 – 1.28 0.716 46 412 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.899 0.596 – 1.37 0.601 23 307 exclusion phecode
381.9 Otorrhea Sense Organs 1.25 0.922 – 1.7 0.148 55 518 exclusion phecode
382 Otalgia Sense Organs 0.866 0.648 – 1.16 0.321 52 635 exclusion phecode
383 Otosclerosis Sense Organs 1.25 0.948 – 1.65 0.112 62 730 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.05 0.921 – 1.21 0.437 229 2494 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.06 0.912 – 1.23 0.459 188 2026 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.949 0.793 – 1.14 0.569 130 1405 exclusion phecode
385.3 Cholesteatoma Sense Organs 0.998 0.812 – 1.23 0.986 100 1018 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.01 0.751 – 1.35 0.969 46 537 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.984 0.879 – 1.1 0.777 328 3930 exclusion phecode
386.1 Meniere's disease Sense Organs 1.06 0.871 – 1.3 0.548 104 1399 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 1.02 0.798 – 1.29 0.902 80 842 exclusion phecode
386.3 Labyrinthitis Sense Organs 0.891 0.75 – 1.06 0.185 138 1628 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.03 0.96 – 1.11 0.374 758 8897 exclusion phecode
388 Other disorders of ear Sense Organs 1.26 0.901 – 1.77 0.17 36 422 exclusion phecode
389 Hearing loss Sense Organs 1.01 0.934 – 1.09 0.807 685 7677 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 1.14 0.904 – 1.43 0.273 77 794 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.11 0.885 – 1.39 0.367 78 920 exclusion phecode
389.4 Tinnitus Sense Organs 0.883 0.709 – 1.1 0.264 84 982 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 0.992 0.92 – 1.07 0.842 742 8035 exclusion phecode
394.2 Mitral valve disease Circulatory System 0.986 0.897 – 1.09 0.779 467 5168 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.05 0.895 – 1.22 0.569 181 1910 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 0.936 0.801 – 1.1 0.405 160 1909 exclusion phecode
395 Heart valve disorders Circulatory System 0.997 0.919 – 1.08 0.94 632 6815 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.99 0.898 – 1.09 0.837 439 4900 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.745 0.535 – 1.03 0.0729 42 407 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 0.844 0.473 – 1.53 0.54 13 180 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.06 0.628 – 1.79 0.819 13 130 exclusion phecode
395.6 Heart valve replaced Circulatory System 0.911 0.793 – 1.05 0.187 215 2071 exclusion phecode
396 Abnormal heart sounds Circulatory System 0.97 0.853 – 1.1 0.645 243 2670 exclusion phecode
401 Hypertension Circulatory System 0.987 0.937 – 1.04 0.145 12363 54260 exclusion phecode
401.1 Essential hypertension Circulatory System 0.987 0.938 – 1.04 0.15 12336 54260 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.03 0.907 – 1.18 0.627 248 2895 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 0.998 0.704 – 1.42 0.989 36 410 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.03 0.892 – 1.18 0.712 212 2519 exclusion phecode
401.3 Other hypertensive complications Circulatory System 0.834 0.48 – 1.44 0.483 13 200 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.06 0.931 – 1.21 0.37 232 2672 exclusion phecode
411 Ischemic Heart Disease Circulatory System 0.975 0.942 – 1.01 0.145 3571 38829 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.954 0.879 – 1.04 0.263 618 7073 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.03 0.965 – 1.1 0.392 1044 11600 exclusion phecode
411.3 Angina pectoris Circulatory System 0.975 0.931 – 1.02 0.277 1933 23334 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 0.99 0.942 – 1.04 0.678 1741 20195 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.904 0.741 – 1.1 0.314 104 1050 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.995 0.944 – 1.05 0.854 1483 18282 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.03 0.849 – 1.25 0.759 111 1290 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.04 0.897 – 1.21 0.598 193 2033 exclusion phecode
414.2 ASCVD Circulatory System 0.96 0.905 – 2.84 0.925 4 96 exclusion phecode
415 Pulmonary heart disease Circulatory System 1 0.93 – 1.08 0.927 733 8057 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.21 0.784 – 1.9 0.381 22 157 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.868 0.707 – 1.07 0.17 99 1135 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 0.781 0.62 – 0.985 0.0341 80 910 exclusion phecode
416 Cardiomegaly Circulatory System 0.919 0.821 – 1.03 0.142 318 3555 exclusion phecode
418 Nonspecific chest pain Circulatory System 0.99 0.961 – 1.02 0.504 4675 52910 exclusion phecode
418.1 Precordial pain Circulatory System 0.975 0.895 – 1.06 0.57 540 6983 exclusion phecode
420 Carditis Circulatory System 0.983 0.872 – 1.11 0.775 294 3169 exclusion phecode
420.1 Myocarditis Circulatory System 0.81 0.737 – 0.88 0.387 14 142 exclusion phecode
420.2 Pericarditis Circulatory System 0.976 0.835 – 1.14 0.761 170 1893 exclusion phecode
420.21 Acute pericarditis Circulatory System 0.83 0.525 – 1.29 0.403 25 253 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.36 0.736 – 2.68 0.309 11 155 exclusion phecode
420.3 Endocarditis Circulatory System 0.981 0.813 – 1.18 0.839 119 1224 exclusion phecode
425 Cardiomyopathy Circulatory System 0.88 0.752 – 1.03 0.11 163 1649 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.866 0.737 – 1.02 0.0795 158 1610 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.821 0.506 – 1.32 0.402 18 171 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.957 0.638 – 1.43 0.828 27 219 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 0.893 0.865 – 1.03 0.884 1 11 exclusion phecode
426 Cardiac conduction disorders Circulatory System 0.968 0.903 – 1.04 0.368 841 9675 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 0.945 0.825 – 1.08 0.409 219 2511 exclusion phecode
426.21 First degree AV block Circulatory System 0.998 0.808 – 1.23 0.984 89 1073 exclusion phecode
426.23 Second degree AV block Circulatory System 0.735 0.544 – 0.992 0.0417 51 504 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 0.972 0.753 – 1.26 0.827 63 752 exclusion phecode
426.25 Other heart block Circulatory System 0.967 0.556 – 1.68 0.897 12 177 exclusion phecode
426.3 Bundle branch block Circulatory System 1.02 0.921 – 1.12 0.748 427 4982 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.06 0.896 – 1.25 0.509 152 1845 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.04 0.921 – 1.18 0.501 265 2968 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.711 0.496 – 1.01 0.0557 34 353 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.03 0.431 – 2.31 0.94 7 99 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.883 0.78 – 1 0.0503 265 3118 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.868 0.764 – 0.986 0.029 248 2925 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 0.993 0.96 – 1.03 0.686 3580 38263 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 0.951 0.866 – 1.05 0.296 472 5581 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.915 0.825 – 1.01 0.0892 398 4714 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.14 0.904 – 1.44 0.266 76 923 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 0.986 0.941 – 1.03 0.574 1854 20121 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.98 0.885 – 1.08 0.691 417 4570 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.13 0.943 – 1.34 0.188 132 1457 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.14 0.711 – 1.84 0.564 16 256 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.1 0.912 – 1.33 0.316 119 1296 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.06 0.894 – 1.26 0.491 141 1740 exclusion phecode
427.6 Premature beats Circulatory System 0.959 0.763 – 1.21 0.716 80 810 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1.4 0.865 – 2.29 0.157 15 187 exclusion phecode
427.7 Tachycardia NOS Circulatory System 0.928 0.836 – 1.03 0.162 378 4175 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.814 0.628 – 1.05 0.111 68 734 exclusion phecode
427.9 Palpitations Circulatory System 0.994 0.925 – 1.07 0.862 842 9275 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.98 0.902 – 1.06 0.624 614 6761 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.05 0.922 – 1.21 0.438 242 2744 exclusion phecode
428.2 Heart failure NOS Circulatory System 0.967 0.878 – 1.06 0.49 459 5052 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.2 0.985 – 1.47 0.068 109 1347 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.06 0.385 – 4.99 0.899 3 43 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.28 1.01 – 1.62 0.0395 73 955 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 0.969 0.672 – 1.4 0.865 36 385 exclusion phecode
430 Intracranial hemorrhage Circulatory System 0.979 0.875 – 1.1 0.716 326 3460 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.01 0.875 – 1.18 0.849 185 2007 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 0.9 0.747 – 1.08 0.262 124 1294 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.1 0.746 – 1.64 0.614 26 341 exclusion phecode
433 Cerebrovascular disease Circulatory System 0.947 0.895 – 1 0.0568 1288 14375 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.931 0.786 – 1.11 0.411 145 1613 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 0.89 0.639 – 1.24 0.479 39 374 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.948 0.868 – 1.03 0.228 536 6141 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.966 0.841 – 1.11 0.619 217 2393 exclusion phecode
433.3 Cerebral ischemia Circulatory System 0.953 0.866 – 1.05 0.33 443 5044 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 0.893 0.797 – 1 0.0485 324 3670 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 0.905 0.738 – 1.11 0.336 98 1038 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.07 0.913 – 1.25 0.409 158 2107 exclusion phecode
440 Atherosclerosis Circulatory System 0.986 0.833 – 1.17 0.872 139 1544 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.718 0.417 – 1.18 0.193 16 135 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.16 0.909 – 1.49 0.225 65 713 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 0.934 0.691 – 1.26 0.652 46 485 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 0.935 0.777 – 1.13 0.47 120 1405 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.985 0.754 – 1.29 0.911 56 631 exclusion phecode
442 Other aneurysm Circulatory System 1.02 0.87 – 1.2 0.793 172 1782 exclusion phecode
442.1 Aortic aneurysm Circulatory System 0.99 0.814 – 1.21 0.92 112 1126 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.09 0.817 – 1.44 0.563 50 518 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 0.93 0.898 – 0.947 0.855 4 39 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.16 0.714 – 1.89 0.538 17 181 exclusion phecode
442.4 Arterial dissection Circulatory System 1.74 0.73 – 4.73 0.217 7 57 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.1 0.758 – 1.59 0.613 32 402 exclusion phecode
443 Peripheral vascular disease Circulatory System 0.966 0.884 – 1.05 0.436 548 6209 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 0.965 0.854 – 1.09 0.564 286 3092 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.46 0.995 – 2.16 0.0501 31 320 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 0.948 0.866 – 1.04 0.239 525 5971 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.925 0.812 – 1.05 0.237 245 3002 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.12 0.905 – 1.38 0.3 95 1071 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.11 0.818 – 1.52 0.487 44 518 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.885 0.757 – 1.04 0.125 174 1901 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.962 0.665 – 1.39 0.833 33 318 exclusion phecode
446.5 Giant cell arteritis Circulatory System 0.85 0.688 – 1.05 0.13 92 1145 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.02 0.734 – 1.41 0.912 42 473 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 0.967 0.815 – 1.15 0.702 139 1604 exclusion phecode
447.1 Stricture of artery Circulatory System 0.898 0.706 – 1.14 0.374 68 907 exclusion phecode
448 Disease of capillaries Circulatory System 0.978 0.695 – 1.38 0.896 37 347 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.1 0.928 – 1.31 0.265 146 1693 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1 0.925 – 1.09 0.945 627 6968 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.996 0.915 – 1.08 0.934 570 6396 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 0.988 0.804 – 1.21 0.91 102 1022 exclusion phecode
454 Varicose veins Circulatory System 1.04 0.995 – 1.08 0.0863 2536 26736 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1.03 0.99 – 1.07 0.15 2772 28947 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.969 0.805 – 1.17 0.74 124 1164 exclusion phecode
455 Hemorrhoids Circulatory System 0.994 0.962 – 1.03 0.7 3991 45140 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.15 0.796 – 1.68 0.442 26 300 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.818 0.757 – 0.873 0.361 18 161 exclusion phecode
458 Hypotension Circulatory System 1.02 0.953 – 1.09 0.616 970 11040 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.06 0.918 – 1.22 0.433 195 2278 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 0.928 0.666 – 1.29 0.652 37 380 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.02 0.94 – 1.11 0.611 579 6693 exclusion phecode
459 Other disorders of circulatory system Circulatory System 0.999 0.96 – 1.04 0.977 2551 29966 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.32 0.855 – 2.1 0.201 21 234 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 0.997 0.958 – 1.04 0.889 2528 29682 exclusion phecode
464 Acute sinusitis Respiratory 1.07 0.735 – 1.58 0.704 28 453 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.981 0.888 – 1.08 0.699 418 4778 exclusion phecode
465.2 Acute pharyngitis Respiratory 0.989 0.836 – 1.17 0.897 152 1743 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.911 0.604 – 1.37 0.647 30 352 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.985 0.9 – 1.08 0.746 513 5953 exclusion phecode
471 Nasal polyps Respiratory 0.916 0.83 – 1.01 0.0791 428 4105 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.1 0.927 – 1.31 0.275 145 1656 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 0.971 0.878 – 1.07 0.566 420 4899 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.01 0.634 – 1.62 0.957 21 197 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.02 0.711 – 1.48 0.912 31 502 exclusion phecode
473.4 Voice disturbance Respiratory 0.991 0.853 – 1.15 0.91 183 2341 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1.05 0.907 – 1.21 0.528 187 2340 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.09 0.836 – 1.42 0.528 56 722 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.03 0.872 – 1.22 0.706 140 1597 exclusion phecode
475 Chronic sinusitis Respiratory 0.905 0.821 – 0.999 0.0458 431 5120 exclusion phecode
476 Allergic rhinitis Respiratory 0.879 0.756 – 1.02 0.0907 185 1965 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 0.985 0.887 – 1.1 0.78 363 3957 exclusion phecode
478 Throat pain Respiratory 1.01 0.808 – 1.27 0.923 84 808 exclusion phecode
479 Other upper respiratory disease Respiratory 1.03 0.948 – 1.12 0.472 589 6716 exclusion phecode
480 Pneumonia Respiratory 1.01 0.96 – 1.06 0.695 1613 17589 exclusion phecode
480.1 Bacterial pneumonia Respiratory 0.989 0.928 – 1.05 0.732 1038 11601 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 0.982 0.919 – 1.05 0.604 928 10382 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.8 1.06 – 3.18 0.0264 14 177 exclusion phecode
480.2 Viral pneumonia Respiratory 1.51 0.832 – 2.84 0.165 12 132 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.13 0.658 – 1.98 0.646 16 137 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.959 0.799 – 1.15 0.654 127 1192 exclusion phecode
481 Influenza Respiratory 1.07 0.823 – 1.39 0.612 64 638 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.646 0.449 – 0.92 0.0138 31 422 exclusion phecode
495 Asthma Respiratory 1.01 0.985 – 1.05 0.326 4832 54529 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.16 0.864 – 1.57 0.309 44 530 exclusion phecode
496 Chronic airway obstruction Respiratory 0.986 0.939 – 1.04 0.588 1721 19932 exclusion phecode
496.1 Emphysema Respiratory 1.01 0.888 – 1.15 0.879 245 2848 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.02 0.924 – 1.12 0.703 434 5493 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.01 0.914 – 1.12 0.815 399 5001 exclusion phecode
496.3 Bronchiectasis Respiratory 1.05 0.952 – 1.17 0.309 409 4630 exclusion phecode
497 Bronchitis Respiratory 1.14 0.925 – 1.4 0.222 97 1263 exclusion phecode
500 Lung disease due to external agents Respiratory 1.09 0.773 – 1.58 0.6 36 356 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.821 0.487 – 1.37 0.423 16 168 exclusion phecode
500.2 Pneumoconiosis Respiratory 0.855 0.448 – 1.65 0.629 8 58 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 0.917 0.74 – 1.14 0.426 91 881 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.06 0.888 – 1.26 0.525 139 1544 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 0.9 0.721 – 1.13 0.351 78 827 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.15 0.896 – 1.49 0.267 67 660 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.18 0.693 – 2.03 0.534 14 141 exclusion phecode
506 Empyema and pneumothorax Respiratory 0.908 0.769 – 1.07 0.253 157 1511 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.03 0.963 – 1.1 0.411 960 10607 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.99 0.88 – 1.11 0.861 299 3573 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.01 0.906 – 1.12 0.908 367 4210 exclusion phecode
509.1 Respiratory failure Respiratory 1.07 0.952 – 1.2 0.257 293 3392 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.04 0.924 – 1.18 0.482 266 3054 exclusion phecode
509.5 Respiratory arrest Respiratory 0.562 0.362 – 0.861 0.0075 25 251 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.88 0.662 – 1.17 0.367 52 605 exclusion phecode
510 Other diseases of lung Respiratory 1.03 0.861 – 1.24 0.728 121 1415 exclusion phecode
512 Other symptoms of respiratory system Respiratory 0.98 0.931 – 1.03 0.44 1607 18103 exclusion phecode
512.1 Wheezing Respiratory 0.848 0.602 – 1.19 0.334 38 453 exclusion phecode
512.2 Painful respiration Respiratory 0.828 0.599 – 1.14 0.242 39 423 exclusion phecode
512.7 Shortness of breath Respiratory 0.974 0.913 – 1.04 0.412 1003 11688 exclusion phecode
512.8 Cough Respiratory 0.991 0.908 – 1.08 0.836 559 5885 exclusion phecode
512.9 Other dyspnea Respiratory 1.04 0.881 – 1.23 0.627 152 1615 exclusion phecode
513 Respiratory abnormalities Respiratory 1.12 0.876 – 1.43 0.363 67 967 exclusion phecode
513.3 Hypoventilation Respiratory 1.04 0.59 – 1.92 0.879 10 135 exclusion phecode
513.4 Hyperventilation Respiratory 1.22 0.91 – 1.64 0.176 46 654 exclusion phecode
513.8 Disorders of diaphragm Respiratory 0.733 0.693 – 1.99 0.401 4 80 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 0.955 0.863 – 1.06 0.373 403 4693 exclusion phecode
516 Abnormal sputum Respiratory 1.08 0.958 – 1.21 0.217 311 3467 exclusion phecode
516.1 Hemoptysis Respiratory 1.09 0.967 – 1.23 0.159 299 3378 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.02 0.973 – 1.08 0.363 1557 17356 exclusion phecode
519.2 Respiratory complications Respiratory 0.946 0.702 – 1.27 0.707 50 596 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.03 0.972 – 1.08 0.355 1461 16254 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.1 0.835 – 1.45 0.497 54 609 exclusion phecode
520 Disorders of tooth development Digestive 1.05 0.929 – 1.18 0.443 288 2979 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.04 0.527 – 2.03 0.894 9 94 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 1.05 0.934 – 1.18 0.421 323 3372 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 0.994 0.901 – 1.1 0.899 449 5166 exclusion phecode
521.1 Dental caries Digestive 0.989 0.897 – 1.09 0.822 453 5161 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 0.957 0.856 – 1.07 0.441 340 3714 exclusion phecode
522.5 Periapical abscess Digestive 0.985 0.857 – 1.13 0.829 217 2470 exclusion phecode
523 Gingival and periodontal diseases Digestive 0.964 0.858 – 1.08 0.536 317 3326 exclusion phecode
523.1 Gingivitis Digestive 1.06 0.734 – 1.54 0.758 28 233 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 0.978 0.847 – 1.13 0.761 207 2230 exclusion phecode
523.31 Acute periodontitis Digestive 0.917 0.744 – 1.13 0.407 100 1184 exclusion phecode
523.32 Chronic periodontitis Digestive 1.03 0.849 – 1.24 0.789 115 1178 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.869 0.623 – 1.21 0.4 41 459 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.805 0.51 – 1.16 0.21 34 379 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.936 0.853 – 1.03 0.164 481 5354 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.53 0.902 – 2.68 0.102 15 178 exclusion phecode
526 Diseases of the jaws Digestive 0.946 0.815 – 1.1 0.458 181 1927 exclusion phecode
526.1 Cysts of the jaws Digestive 1.04 0.773 – 1.4 0.798 50 523 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.01 0.516 – 1.97 0.987 9 106 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 0.941 0.728 – 1.21 0.635 60 636 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.947 0.732 – 1.22 0.67 60 641 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.846 0.497 – 1.42 0.503 15 206 exclusion phecode
526.9 Jaw disease NOS Digestive 0.823 0.626 – 1.08 0.153 57 523 exclusion phecode
527 Diseases of the salivary glands Digestive 1.08 0.905 – 1.29 0.392 132 1574 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.03 0.593 – 1.78 0.922 16 193 exclusion phecode
527.2 Sialoadenitis Digestive 1.1 0.881 – 1.39 0.385 79 873 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.14 0.58 – 2.32 0.685 10 141 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.32 0.892 – 1.99 0.154 23 283 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.962 0.893 – 1.04 0.308 753 7923 exclusion phecode
528.1 Stomatitis and mucositis Digestive 0.95 0.774 – 1.17 0.621 95 1013 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.918 0.732 – 1.15 0.451 81 874 exclusion phecode
528.12 Oral aphthae Digestive 1.05 0.631 – 1.75 0.851 15 147 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.44 0.958 – 2.2 0.0753 25 308 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.842 0.547 – 1.28 0.41 22 234 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.946 0.581 – 1.52 0.814 17 173 exclusion phecode
528.5 Diseases of lips Digestive 0.904 0.76 – 1.08 0.252 133 1393 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.08 0.834 – 1.39 0.568 69 657 exclusion phecode
528.7 Sialolithiasis Digestive 0.889 0.683 – 1.16 0.378 58 507 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.02 0.893 – 1.16 0.775 247 2679 exclusion phecode
529.1 Glossitis Digestive 0.857 0.646 – 1.13 0.276 56 590 exclusion phecode
530 Diseases of esophagus Digestive 0.996 0.97 – 1.02 0.771 6123 56943 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.997 0.97 – 1.02 0.829 5744 56038 exclusion phecode
530.11 GERD Digestive 0.997 0.967 – 1.03 0.867 4324 49137 exclusion phecode
530.12 Ulcer of esophagus Digestive 0.982 0.908 – 1.06 0.642 695 8038 exclusion phecode
530.14 Reflux esophagitis Digestive 1.01 0.963 – 1.06 0.691 1838 20721 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.08 0.947 – 1.22 0.259 261 3008 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 0.917 0.81 – 1.04 0.173 257 2977 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.11 0.933 – 1.33 0.233 133 1451 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.81 0.522 – 1.23 0.317 24 273 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.04 0.8 – 1.35 0.775 57 475 exclusion phecode
530.9 Heartburn Digestive 0.937 0.854 – 1.03 0.164 492 5509 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.944 0.888 – 1 0.063 1123 12567 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.996 0.782 – 1.27 0.975 74 788 exclusion phecode
531.2 Gastric ulcer Digestive 0.917 0.851 – 0.988 0.0233 746 8245 exclusion phecode
531.3 Duodenal ulcer Digestive 0.968 0.873 – 1.07 0.532 398 4355 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 0.867 0.653 – 1.15 0.314 52 721 exclusion phecode
532 Dysphagia Digestive 0.997 0.94 – 1.06 0.907 1234 14225 exclusion phecode
535 Gastritis and duodenitis Digestive 0.988 0.96 – 1.02 0.401 5262 54923 exclusion phecode
535.1 Acute gastritis Digestive 0.976 0.848 – 1.12 0.739 221 2376 exclusion phecode
535.2 Atrophic gastritis Digestive 1.24 0.961 – 1.62 0.095 61 723 exclusion phecode
535.6 Duodenitis Digestive 1.01 0.95 – 1.08 0.725 1077 12640 exclusion phecode
535.8 Other specified gastritis Digestive 1.01 0.956 – 1.06 0.794 1611 18197 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.28 0.76 – 2.31 0.333 15 215 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.02 0.765 – 1.35 0.911 53 562 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 0.976 0.9 – 1.06 0.564 631 6966 exclusion phecode
540 Appendiceal conditions Digestive 1 0.915 – 1.09 0.993 534 5340 exclusion phecode
540.1 Appendicitis Digestive 1.01 0.921 – 1.11 0.834 498 4968 exclusion phecode
540.11 Acute appendicitis Digestive 0.972 0.882 – 1.07 0.566 447 4388 exclusion phecode
550 Abdominal hernia Digestive 0.986 0.961 – 1.01 0.28 6384 57607 exclusion phecode
550.1 Inguinal hernia Digestive 0.998 0.901 – 1.1 0.962 411 4125 exclusion phecode
550.2 Diaphragmatic hernia Digestive 0.979 0.952 – 1.01 0.143 5328 53750 exclusion phecode
550.3 Femoral hernia Digestive 1.06 0.916 – 1.22 0.45 213 1809 exclusion phecode
550.4 Umbilical hernia Digestive 1.01 0.905 – 1.14 0.817 325 3473 exclusion phecode
550.5 Ventral hernia Digestive 1 0.918 – 1.1 0.942 508 6297 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.02 0.945 – 1.09 0.663 786 8276 exclusion phecode
555.1 Regional enteritis Digestive 1.04 0.923 – 1.17 0.539 312 3455 exclusion phecode
555.2 Ulcerative colitis Digestive 1.01 0.925 – 1.1 0.83 555 5661 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 0.959 0.782 – 1.18 0.685 102 878 exclusion phecode
556 Ulceration of the lower GI tract Digestive 0.961 0.833 – 1.11 0.587 201 2257 exclusion phecode
556.1 Ulceration of intestine Digestive 0.945 0.786 – 1.14 0.546 126 1386 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.09 0.844 – 1.42 0.494 63 689 exclusion phecode
557.1 Celiac disease Digestive 0.987 0.893 – 1.09 0.794 419 4466 exclusion phecode
558 Noninfectious gastroenteritis Digestive 0.981 0.946 – 1.02 0.315 3058 35914 exclusion phecode
559 Ileostomy status Digestive 1.06 0.936 – 1.19 0.377 273 2825 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.04 0.967 – 1.12 0.273 711 8502 exclusion phecode
560.1 Paralytic ileus Digestive 1.2 0.928 – 1.55 0.164 64 719 exclusion phecode
560.2 Impaction of intestine Digestive 0.801 0.609 – 1.05 0.107 51 651 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.855 0.725 – 1.01 0.062 145 1968 exclusion phecode
560.4 Other intestinal obstruction Digestive 1.06 0.975 – 1.14 0.181 631 7573 exclusion phecode
561 Symptoms involving digestive system Digestive 0.998 0.965 – 1.03 0.912 3564 40538 exclusion phecode
561.1 Diarrhea Digestive 1.04 0.862 – 1.25 0.703 126 1196 exclusion phecode
561.2 Flatulence Digestive 1.01 0.908 – 1.13 0.825 351 4074 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 0.978 0.951 – 1.01 0.136 5187 46555 exclusion phecode
562.1 Diverticulosis Digestive 0.979 0.951 – 1.01 0.146 5179 46555 exclusion phecode
563 Constipation Digestive 0.977 0.933 – 1.02 0.309 1999 23784 exclusion phecode
564 Functional digestive disorders Digestive 0.979 0.948 – 1.01 0.208 3898 45036 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 0.959 0.906 – 1.02 0.158 1254 15443 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.02 0.919 – 1.14 0.67 344 4072 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 0.994 0.954 – 1.04 0.789 2408 29236 exclusion phecode
565 Anal and rectal conditions Digestive 0.975 0.934 – 1.02 0.266 2182 25167 exclusion phecode
565.1 Anal and rectal polyp Digestive 0.948 0.891 – 1.01 0.0935 1073 12281 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.06 0.89 – 1.26 0.517 132 1555 exclusion phecode
568 Other disorders of peritoneum Digestive 1.06 0.969 – 1.15 0.215 554 7571 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.04 0.955 – 1.14 0.357 531 7238 exclusion phecode
569 Other disorders of intestine Digestive 0.996 0.924 – 1.07 0.91 735 8839 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.57 1.02 – 2.43 0.0349 24 305 exclusion phecode
569.2 Gastrointestinal complications Digestive 0.992 0.76 – 1.3 0.949 52 852 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.06 0.956 – 1.17 0.285 420 5233 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.06 0.927 – 1.2 0.417 243 3156 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.26 0.779 – 2.06 0.336 17 188 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.08 0.851 – 1.37 0.52 73 837 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.06 0.867 – 1.29 0.573 103 1229 exclusion phecode
571.81 Portal hypertension Digestive 1.09 0.835 – 1.44 0.509 56 651 exclusion phecode
572 Ascites (non malignant) Digestive 1.04 0.924 – 1.18 0.488 297 3098 exclusion phecode
573 Other disorders of liver Digestive 0.987 0.874 – 1.11 0.827 278 3155 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.32 0.742 – 2.52 0.354 13 108 exclusion phecode
573.3 Hepatomegaly Digestive 1.05 0.719 – 1.55 0.784 31 403 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 0.941 0.797 – 1.11 0.471 155 1441 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.05 0.971 – 1.14 0.205 623 6917 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.38 0.928 – 2.07 0.11 27 266 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.01 0.974 – 1.04 0.662 3663 41738 exclusion phecode
574.1 Cholelithiasis Digestive 1.02 0.984 – 1.06 0.269 3239 36901 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.09 0.973 – 1.22 0.138 314 3794 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.04 0.98 – 1.1 0.204 1284 14921 exclusion phecode
574.2 Calculus of bile duct Digestive 0.996 0.917 – 1.08 0.932 585 6618 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.984 0.906 – 1.07 0.702 605 6636 exclusion phecode
575 Other biliary tract disease Digestive 0.978 0.91 – 1.05 0.545 791 9272 exclusion phecode
575.1 Cholangitis Digestive 1.43 1.13 – 1.82 0.00322 78 773 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.15 0.961 – 1.39 0.124 122 1312 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 1.01 0.822 – 1.24 0.931 95 1200 exclusion phecode
575.7 Other disorders of gallbladder Digestive 0.937 0.836 – 1.05 0.261 322 3746 exclusion phecode
575.8 Other disorders of biliary tract Digestive 0.952 0.837 – 1.08 0.457 251 2849 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.24 0.941 – 1.64 0.12 53 765 exclusion phecode
577 Diseases of pancreas Digestive 1.09 0.992 – 1.2 0.0716 453 5342 exclusion phecode
577.1 Acute pancreatitis Digestive 1.12 1 – 1.25 0.0467 342 4034 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.04 0.771 – 1.39 0.807 46 606 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.857 0.665 – 1.1 0.223 59 721 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.979 – 1.05 0.468 3589 40052 exclusion phecode
578.1 Hematemesis Digestive 1.15 1.01 – 1.31 0.0414 258 2908 exclusion phecode
578.2 Blood in stool Digestive 1.04 0.932 – 1.16 0.497 366 4409 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1 0.964 – 1.05 0.827 2419 27041 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.03 0.96 – 1.1 0.426 888 9722 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.06 0.944 – 1.18 0.338 328 3727 exclusion phecode
579.2 Splenomegaly Digestive 1.59 1.14 – 2.25 0.00655 43 501 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.966 0.863 – 1.08 0.554 326 3724 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.15 1.01 – 1.32 0.0414 231 2769 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.11 0.942 – 1.3 0.213 158 2081 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.77 0.935 – 3.52 0.0699 10 130 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.53 0.94 – 2.57 0.0849 20 242 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.02 0.855 – 1.22 0.826 133 1730 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.12 0.861 – 1.45 0.403 63 653 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.52 1.09 – 2.15 0.0141 40 392 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.54 1.11 – 2.18 0.0102 41 409 exclusion phecode
585 Renal failure Genitourinary 0.937 0.878 – 1 0.0498 972 10578 exclusion phecode
585.1 Acute renal failure Genitourinary 0.972 0.896 – 1.05 0.495 632 6598 exclusion phecode
585.2 Renal failure NOS Genitourinary 0.817 0.7 – 0.954 0.0103 175 2009 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.922 0.828 – 1.03 0.137 367 4185 exclusion phecode
585.31 Renal dialysis Genitourinary 1.09 0.843 – 1.41 0.508 61 605 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.08 0.978 – 1.18 0.135 454 5436 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.06 0.713 – 1.6 0.757 27 351 exclusion phecode
586.11 Small kidney Genitourinary 1.11 0.706 – 1.77 0.65 23 309 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.01 0.862 – 1.19 0.867 157 2032 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.966 0.558 – 1.75 0.899 10 96 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.09 0.914 – 1.29 0.346 135 1511 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.07 0.804 – 1.42 0.642 47 487 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 0.983 0.663 – 1.47 0.929 23 215 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 0.991 0.65 – 1.5 0.964 20 211 exclusion phecode
590 Pyelonephritis Genitourinary 0.975 0.863 – 1.1 0.69 276 3232 exclusion phecode
591 Urinary tract infection Genitourinary 0.994 0.952 – 1.04 0.766 2323 27681 exclusion phecode
592 Cystitis and urethritis Genitourinary 0.955 0.88 – 1.04 0.272 616 7211 exclusion phecode
592.1 Cystitis Genitourinary 0.956 0.88 – 1.04 0.279 613 7157 exclusion phecode
592.11 Acute cystitis Genitourinary 0.942 0.644 – 1.38 0.753 29 290 exclusion phecode
592.12 Chronic cystitis Genitourinary 0.926 0.798 – 1.07 0.306 193 2219 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 0.872 0.672 – 1.13 0.29 64 770 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.891 0.593 – 1.35 0.564 22 260 exclusion phecode
593 Hematuria Genitourinary 1.02 0.979 – 1.06 0.347 2558 27114 exclusion phecode
594 Urinary calculus Genitourinary 0.969 0.893 – 1.05 0.459 611 7224 exclusion phecode
594.1 Calculus of kidney Genitourinary 0.968 0.866 – 1.08 0.559 342 3924 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.08 0.785 – 1.49 0.632 40 516 exclusion phecode
594.3 Calculus of ureter Genitourinary 0.974 0.842 – 1.13 0.721 196 2191 exclusion phecode
594.8 Renal colic Genitourinary 0.909 0.78 – 1.06 0.221 180 2181 exclusion phecode
595 Hydronephrosis Genitourinary 1.02 0.898 – 1.16 0.769 263 2913 exclusion phecode
596 Other disorders of bladder Genitourinary 1 0.943 – 1.07 0.888 1039 13582 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.5 0.883 – 2.63 0.119 16 298 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1.07 0.938 – 1.22 0.319 248 3576 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1 0.921 – 1.09 0.981 604 6860 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.995 0.902 – 1.1 0.917 440 5108 exclusion phecode
597.2 Urinary complications NEC Genitourinary 0.924 0.513 – 1.71 0.784 11 156 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 0.987 0.893 – 1.09 0.798 405 4739 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.07 0.796 – 1.46 0.637 48 577 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.975 – 1.05 0.574 3208 40739 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.903 0.565 – 1.43 0.658 21 174 exclusion phecode
599.2 Retention of urine Genitourinary 0.984 0.898 – 1.08 0.733 488 6137 exclusion phecode
599.3 Dysuria Genitourinary 0.892 0.76 – 1.05 0.158 169 2043 exclusion phecode
599.4 Urinary incontinence Genitourinary 1.03 0.983 – 1.07 0.232 2148 28699 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 0.974 0.894 – 1.06 0.541 562 6631 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.49 0.978 – 2.31 0.066 23 175 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 0.779 0.43 – 1.39 0.379 13 151 exclusion phecode
599.9 Other abnormality of urination Genitourinary 0.822 0.705 – 0.959 0.0123 173 2281 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.955 0.884 – 1.03 0.239 712 8349 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.966 0.862 – 1.08 0.555 324 3492 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 0.913 0.742 – 1.13 0.388 95 1095 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 0.777 0.627 – 0.96 0.0187 98 1097 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 1.01 0.904 – 1.12 0.903 356 4364 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.02 0.898 – 1.16 0.765 261 2616 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.06 0.967 – 1.16 0.219 527 5591 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.914 0.602 – 1.38 0.666 28 229 exclusion phecode
611.3 Lump or mass in breast Genitourinary 1.07 0.978 – 1.18 0.135 502 5338 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.04 0.902 – 1.2 0.582 198 2268 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.06 0.911 – 1.22 0.471 191 2168 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 0.996 0.599 – 1.68 0.988 14 189 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.96 0.88 – 1.05 0.36 542 5652 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 0.925 0.807 – 1.06 0.258 232 2424 exclusion phecode
613.5 Mastodynia Genitourinary 0.845 0.525 – 1.34 0.458 20 228 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.931 0.818 – 1.06 0.28 241 2511 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1 0.836 – 1.2 0.983 118 1101 exclusion phecode
613.9 Breast disorder NOS Genitourinary 1.13 0.896 – 1.43 0.303 78 811 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.03 0.974 – 1.09 0.317 1407 17653 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.994 0.907 – 1.09 0.891 505 7303 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.01 0.865 – 1.17 0.939 180 2307 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.902 0.376 – 0.95 0.687 9 194 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.13 0.915 – 1.39 0.256 100 1222 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.06 0.829 – 1.35 0.648 67 960 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.06 0.838 – 1.34 0.636 78 848 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.05 0.973 – 1.13 0.209 755 8763 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.04 0.935 – 1.16 0.468 365 4640 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.983 0.82 – 1.18 0.848 134 1555 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.05 0.917 – 1.2 0.473 234 2384 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.03 0.808 – 1.32 0.801 74 860 exclusion phecode
615 Endometriosis Genitourinary 0.965 0.894 – 1.04 0.364 711 11051 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 0.954 0.76 – 1.2 0.681 80 1055 exclusion phecode
618 Genital prolapse Genitourinary 0.993 0.961 – 1.03 0.686 3882 46658 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.998 0.957 – 1.04 0.934 2303 29678 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.991 0.947 – 1.04 0.689 2037 21638 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.01 0.828 – 1.24 0.895 99 2138 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.01 0.863 – 1.19 0.883 158 2783 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1 0.964 – 1.04 0.913 2803 29683 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.18 1.01 – 1.38 0.0322 184 2289 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 0.992 0.936 – 1.05 0.779 1253 12362 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.01 0.946 – 1.08 0.742 932 9345 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.02 0.93 – 1.11 0.707 524 5961 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.913 0.824 – 1.01 0.0815 384 4375 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 0.828 0.568 – 1.21 0.316 28 248 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.992 0.891 – 1.11 0.884 374 4298 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.988 0.956 – 1.02 0.459 4062 39495 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.993 0.957 – 1.03 0.725 3007 29583 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 0.956 0.904 – 1.01 0.107 1401 13133 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.01 0.903 – 1.14 0.815 320 3941 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.944 0.841 – 1.06 0.323 320 3359 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.871 0.697 – 1.09 0.218 85 978 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 0.924 0.796 – 1.07 0.297 196 1897 exclusion phecode
624.9 stress incontinence, female Genitourinary 1.03 0.983 – 1.09 0.196 1638 22082 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.996 0.922 – 1.08 0.921 719 8131 exclusion phecode
625.1 Dyspareunia Genitourinary 1.02 0.902 – 1.16 0.715 262 3225 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.977 0.943 – 1.01 0.202 3367 38946 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.974 0.939 – 1.01 0.169 2995 36734 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 1.19 0.8 – 1.8 0.383 29 271 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 0.957 0.912 – 1.01 0.0797 1736 28358 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 1 0.92 – 1.09 0.992 617 7000 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.957 0.895 – 1.02 0.191 949 11474 exclusion phecode
626.2 Dysmenorrhea Genitourinary 1.08 0.947 – 1.22 0.261 259 4528 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.624 0.337 – 1.11 0.0893 13 390 exclusion phecode
626.8 Infertility, female Genitourinary 0.964 0.838 – 1.11 0.602 212 2161 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.04 1.01 – 1.08 0.00503 4738 44205 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 1.04 1 – 1.07 0.0303 4295 38760 exclusion phecode
627.2 Symptomatic menopause Genitourinary 1.61 1.18 – 2.23 0.00234 41 760 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.05 0.958 – 1.15 0.301 492 4822 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1 0.812 – 1.24 0.975 90 1220 exclusion phecode
628 Ovarian cyst Genitourinary 1 0.944 – 1.07 0.9 1109 14895 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.01 0.915 – 1.11 0.846 454 4082 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.04 0.842 – 1.29 0.703 98 883 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.2 0.845 – 1.73 0.303 37 348 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.04 0.851 – 1.27 0.701 99 905 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.18 0.875 – 1.61 0.274 47 430 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.933 0.733 – 1.19 0.574 68 589 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.921 0.758 – 1.11 0.368 129 1166 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.985 0.68 – 1.44 0.935 36 284 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.937 0.767 – 1.14 0.522 112 1080 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 0.931 0.318 – 2.98 0.885 1 30 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.844 0.643 – 1.11 0.218 60 545 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.699 0.408 – 1.18 0.175 19 154 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.22 0.639 – 2.49 0.541 10 91 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.03 0.503 – 2.06 0.937 10 107 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.1 0.855 – 1.43 0.445 71 610 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.95 0.785 – 1.15 0.591 109 1050 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.984 0.442 – 2.32 0.967 7 60 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.824 0.485 – 1.41 0.468 14 109 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.527 0.109 – 1.49 0.236 4 58 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.1 0.529 – 2.17 0.766 9 111 exclusion phecode
650 Normal delivery Pregnancy Complications 1.03 0.831 – 1.29 0.758 90 967 exclusion phecode
651 Multiple gestation Pregnancy Complications 1.06 0.634 – 1.84 0.813 19 152 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1.02 0.818 – 1.28 0.845 87 846 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.05 0.726 – 1.13 0.675 57 628 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 0.954 0.446 – 2.17 0.905 9 54 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.949 0.882 – 1.01 0.411 223 2069 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.977 0.381 – 2.51 0.956 4 54 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 1.02 0.829 – 1.25 0.873 100 984 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 1.08 1.01 – 1.23 0.636 36 322 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.981 0.923 – 1.04 0.732 255 2193 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.852 0.715 – 1.02 0.0713 140 1354 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.14 1.07 – 1.24 0.606 12 88 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.924 0.868 – 0.989 0.732 13 114 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.74 0.658 – 5.66 0.289 5 33 exclusion phecode
679 Complications of in utero procedures Dermatologic 1.45 0.4 – 9.84 0.608 4 25 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.02 0.961 – 1.09 0.468 1042 11411 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.786 0.628 – 0.98 0.0317 87 915 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.28 1.05 – 1.57 0.0157 100 1154 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.03 0.956 – 1.11 0.427 735 7974 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.03 0.957 – 1.11 0.421 736 7971 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.03 0.952 – 1.11 0.486 733 7922 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.04 0.855 – 1.26 0.705 110 1277 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.05 0.913 – 1.21 0.483 216 2345 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.02 0.909 – 1.15 0.709 314 3556 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.12 0.801 – 1.58 0.486 39 436 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 0.938 0.711 – 1.24 0.642 55 730 exclusion phecode
687 Symptoms affecting skin Dermatologic 1.11 0.88 – 1.39 0.383 84 1289 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.09 0.985 – 1.21 0.0932 402 4188 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 0.856 0.637 – 1.15 0.289 50 637 exclusion phecode
687.3 Changes in skin texture Dermatologic 1.31 0.749 – 2.36 0.314 13 253 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1 0.912 – 1.11 0.934 461 5452 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.959 0.902 – 1.02 0.173 1147 11891 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 1.83 0.921 – 6.12 0.13 7 55 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 1.17 1.16 – 1.29 0.668 5 23 exclusion phecode
691 Congenital anomalies of skin Dermatologic 1.02 0.699 – 1.48 0.917 32 253 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.935 0.814 – 1.07 0.34 206 2299 exclusion phecode
694.1 Vitiligo Dermatologic 0.786 0.457 – 1.37 0.358 11 182 exclusion phecode
694.2 Other dyschromia Dermatologic 0.974 0.836 – 1.14 0.738 171 1867 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 0.744 0.473 – 1.17 0.186 20 206 exclusion phecode
695 Erythematous conditions Dermatologic 0.969 0.885 – 1.06 0.489 536 5650 exclusion phecode
695.1 Toxic erythema Dermatologic 1.18 0.728 – 1.91 0.492 19 228 exclusion phecode
695.2 Bullous dermatoses Dermatologic 0.939 0.62 – 1.4 0.754 26 256 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 0.967 0.464 – 2.01 0.923 10 96 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.977 0.588 – 1.6 0.922 15 158 exclusion phecode
695.3 Rosacea Dermatologic 0.86 0.652 – 1.13 0.274 52 546 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 0.971 0.799 – 1.18 0.77 113 1234 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.932 0.647 – 1.34 0.693 32 364 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 0.943 0.764 – 1.17 0.584 95 1035 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 0.99 0.853 – 1.15 0.896 192 2027 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1.09 0.823 – 1.46 0.537 57 565 exclusion phecode
695.81 Erythema nodosum Dermatologic 1.03 0.643 – 1.65 0.91 20 185 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 0.98 0.785 – 1.22 0.856 88 935 exclusion phecode
696 Psoriasis and related disorders Dermatologic 1 0.896 – 1.12 0.998 344 3900 exclusion phecode
696.4 Psoriasis Dermatologic 0.996 0.892 – 1.11 0.944 339 3851 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 1.05 0.918 – 1.19 0.5 246 2821 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.955 0.795 – 1.15 0.62 119 1380 exclusion phecode
697 Sarcoidosis Dermatologic 1.19 0.987 – 1.43 0.0685 122 1157 exclusion phecode
698 Pruritus and related conditions Dermatologic 1.1 0.928 – 1.31 0.268 150 1694 exclusion phecode
700 Corns and callosities Dermatologic 1.39 1.11 – 1.75 0.00483 90 879 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.99 0.926 – 1.06 0.779 919 10713 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 1.02 0.597 – 1.77 0.939 15 184 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.986 0.899 – 1.08 0.77 487 5669 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.911 0.581 – 1.43 0.676 24 191 exclusion phecode
701.4 Keloid scar Dermatologic 0.999 0.731 – 1.37 0.997 42 476 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 0.897 0.716 – 1.12 0.336 80 1022 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.24 0.714 – 2.21 0.413 12 200 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.998 0.941 – 1.06 0.945 1197 12401 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.989 0.907 – 1.08 0.798 545 6014 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 1.01 0.93 – 1.09 0.878 690 6727 exclusion phecode
703 Diseases of nail, NOS Dermatologic 0.872 0.685 – 1.11 0.26 72 771 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.895 0.749 – 1.07 0.217 126 1646 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 1.03 0.963 – 1.1 0.38 930 9617 exclusion phecode
704.1 Alopecia Dermatologic 0.986 0.71 – 1.37 0.93 39 349 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.43 0.807 – 2.66 0.212 12 134 exclusion phecode
705 Disorders of sweat glands Dermatologic 1 0.696 – 1.45 0.989 31 418 exclusion phecode
705.3 Hidradenitis Dermatologic 0.988 0.663 – 1.48 0.953 27 363 exclusion phecode
705.8 Hyperhidrosis Dermatologic 0.893 0.69 – 1.16 0.384 67 768 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1.03 0.974 – 1.08 0.32 1497 15963 exclusion phecode
706.1 Acne Dermatologic 1.49 0.857 – 2.71 0.147 15 150 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1.02 0.966 – 1.07 0.532 1586 16881 exclusion phecode
707 Chronic ulcer of skin Dermatologic 0.988 0.875 – 1.11 0.839 282 2844 exclusion phecode
707.1 Decubitus ulcer Dermatologic 0.963 0.818 – 1.13 0.644 151 1423 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.966 0.9 – 1.04 0.341 829 9111 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.14 0.976 – 1.34 0.0972 171 1839 exclusion phecode
709.3 Systemic sclerosis Dermatologic 0.839 0.639 – 1.1 0.198 65 561 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.08 0.664 – 1.87 0.725 20 173 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.937 0.862 – 1.02 0.126 596 6692 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.991 0.79 – 1.24 0.934 78 841 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1 0.795 – 1.27 0.978 73 777 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.941 0.598 – 1.51 0.787 20 276 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.06 0.822 – 1.37 0.662 60 543 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 0.828 0.634 – 1.08 0.158 56 662 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 0.768 0.565 – 1.04 0.085 49 484 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 0.897 0.443 – 1.9 0.746 10 142 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.21 0.794 – 1.89 0.365 24 205 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.3 0.595 – 3.18 0.517 7 48 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.01 0.957 – 1.08 0.624 1171 13565 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.01 0.949 – 1.07 0.758 1082 12311 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.992 0.879 – 1.12 0.894 282 3548 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.896 0.609 – 1.32 0.563 26 314 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.17 0.901 – 1.52 0.232 61 760 exclusion phecode
716 Other arthropathies Musculoskeletal 1.01 0.976 – 1.05 0.358 7511 56916 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.03 0.954 – 1.11 0.485 760 9731 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.01 0.976 – 1.05 0.464 2747 32575 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.01 0.985 – 1.04 0.41 7143 56584 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.04 0.926 – 1.17 0.494 294 3164 exclusion phecode
720 Spinal stenosis Musculoskeletal 0.942 0.871 – 1.02 0.13 675 8033 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 0.99 0.94 – 1.04 0.69 1536 19218 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1 0.937 – 1.07 0.992 958 12530 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.859 0.558 – 1.3 0.462 25 353 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 0.935 0.727 – 1.2 0.592 64 779 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1 0.949 – 1.06 0.957 1427 17680 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.925 0.689 – 1.22 0.516 69 870 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.03 0.94 – 1.13 0.518 491 6485 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 0.721 0.641 – 2.13 0.451 4 106 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.01 0.931 – 1.09 0.844 671 8077 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.2 0.922 – 1.58 0.167 61 814 exclusion phecode
723.1 Torticollis Musculoskeletal 1.94 1.2 – 3.18 0.00632 20 212 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.01 0.9 – 1.12 0.917 336 3965 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 0.955 0.772 – 1.18 0.668 96 1118 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.974 0.788 – 1.21 0.809 95 1116 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.1 1.03 – 1.2 0.697 12 164 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1 0.878 – 1.14 0.976 236 2779 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.03 0.992 – 1.08 0.116 2510 30838 exclusion phecode
726.1 Enthesopathy Musculoskeletal 1.03 0.979 – 1.08 0.262 1775 21536 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.965 0.751 – 1.24 0.782 67 804 exclusion phecode
726.3 Bursitis Musculoskeletal 1.27 0.962 – 1.69 0.0877 52 681 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.01 0.957 – 1.07 0.727 1445 16754 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.992 0.906 – 1.09 0.869 502 6165 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.82 0.415 – 1.64 0.547 10 111 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.01 0.934 – 1.09 0.804 703 7798 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 1.02 0.844 – 1.22 0.868 115 1377 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.05 0.81 – 1.37 0.689 60 682 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.02 0.654 – 1.63 0.922 22 276 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.07 0.968 – 1.19 0.176 380 3834 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.01 0.759 – 1.34 0.967 55 688 exclusion phecode
728.7 Fasciitis Musculoskeletal 1.09 0.982 – 1.2 0.108 414 4244 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.07 0.963 – 1.2 0.201 355 3521 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.01 0.947 – 1.07 0.832 1093 13777 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.918 0.804 – 1.05 0.205 241 3348 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.904 0.551 – 1.51 0.684 18 189 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.919 0.706 – 1.2 0.521 58 776 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.924 0.706 – 1.21 0.553 55 737 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.968 0.765 – 1.23 0.784 72 816 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.01 0.722 – 1.42 0.941 36 397 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.837 0.793 – 0.951 0.565 5 57 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.02 0.932 – 1.12 0.637 484 4939 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.09 0.882 – 1.34 0.436 90 834 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.978 0.799 – 1.2 0.828 107 1138 exclusion phecode
733.6 Costochondritis Musculoskeletal 1.08 0.756 – 1.54 0.677 33 352 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.06 0.92 – 1.23 0.413 210 2508 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.11 0.683 – 1.83 0.651 18 208 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1 0.963 – 1.04 0.98 2959 33036 exclusion phecode
735.1 Flat foot Musculoskeletal 1.3 0.981 – 1.72 0.0647 51 525 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 1 0.95 – 1.05 0.989 1512 16965 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.956 0.88 – 1.04 0.283 593 6878 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.945 0.855 – 1.04 0.263 418 4794 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.999 0.956 – 1.04 0.946 2187 24370 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1.11 0.989 – 1.24 0.0759 317 3381 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.2 0.893 – 1.61 0.222 44 475 exclusion phecode
737 Curvature of spine Musculoskeletal 1.01 0.898 – 1.15 0.822 290 3359 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.03 0.908 – 1.16 0.666 280 3220 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.02 0.917 – 1.12 0.768 400 4716 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.03 0.924 – 1.15 0.59 345 4108 exclusion phecode
739 Contracture of joint Musculoskeletal 0.969 0.781 – 1.2 0.774 88 1005 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.01 0.981 – 1.04 0.476 5919 53119 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.01 0.978 – 1.05 0.529 3782 39791 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.04 0.988 – 1.09 0.144 1820 20641 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.93 0.728 – 1.19 0.56 69 752 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.982 0.818 – 1.18 0.84 126 1637 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1 0.964 – 1.04 0.859 2544 31216 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.11 1.02 – 1.22 0.0167 563 6754 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 1.09 0.632 – 1.95 0.756 13 184 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.18 0.965 – 1.44 0.105 110 1339 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.869 0.609 – 1.25 0.433 32 307 exclusion phecode
741.4 Joint effusions Musculoskeletal 1.05 0.907 – 1.21 0.529 213 2333 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.06 0.653 – 1.72 0.8 14 190 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.659 0.251 – 1.34 0.194 9 113 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.988 0.892 – 1.09 0.815 407 4700 exclusion phecode
742.1 Loose body in joint Musculoskeletal 0.77 0.555 – 1.07 0.108 38 473 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.821 0.385 – 1.9 0.588 7 133 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 0.89 0.718 – 1.11 0.286 86 929 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 1.05 0.922 – 1.19 0.484 273 3124 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1 0.962 – 1.05 0.836 2272 24171 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1 0.96 – 1.05 0.84 2037 21524 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1 0.954 – 1.05 0.993 1868 19827 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1.15 0.926 – 1.42 0.208 95 944 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.18 0.976 – 1.43 0.086 113 1177 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.02 0.873 – 1.19 0.823 175 1916 exclusion phecode
745 Pain in joint Musculoskeletal 1.01 0.958 – 1.07 0.669 1411 17187 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.02 0.922 – 1.12 0.747 445 4583 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.04 0.939 – 1.15 0.466 413 4265 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.983 0.802 – 1.21 0.869 107 1070 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.881 0.615 – 1.26 0.479 30 319 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.08 0.956 – 1.23 0.205 265 2761 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.825 0.569 – 1.19 0.294 31 334 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.54 0.718 – 4 0.244 5 84 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.12 0.859 – 1.47 0.398 59 490 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.981 0.81 – 1.19 0.841 110 1258 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.18 0.858 – 1.64 0.302 37 480 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1 0.938 – 1.07 0.982 19 257 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.906 0.711 – 1.15 0.419 72 766 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.808 0.58 – 1.12 0.191 41 436 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.02 0.703 – 1.47 0.93 30 294 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.9 0.784 – 1.03 0.13 225 2614 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.987 0.817 – 1.19 0.891 112 1220 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.983 0.814 – 1.19 0.858 114 1231 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.837 0.688 – 1.02 0.0728 113 1407 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.819 0.618 – 1.08 0.154 54 704 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.903 0.676 – 1.21 0.48 51 598 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.14 0.894 – 1.47 0.278 61 666 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.07 0.82 – 1.41 0.607 51 538 exclusion phecode
752.11 Spina bifida Congenital Anomalies 1.15 0.859 – 1.56 0.337 41 428 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.28 0.722 – 2.3 0.371 10 116 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.868 0.601 – 1.26 0.439 31 255 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.05 0.678 – 1.64 0.83 20 163 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.983 0.671 – 1.46 0.928 25 251 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.05 0.847 – 1.3 0.672 91 1019 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.872 0.657 – 1.16 0.338 47 498 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.28 0.888 – 1.86 0.18 31 383 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.57 1.01 – 2.52 0.043 22 254 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.924 0.759 – 1.13 0.431 106 1190 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.732 0.436 – 1.24 0.229 17 152 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.939 0.738 – 1.2 0.603 72 894 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.27 0.802 – 2.05 0.279 17 320 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.75 0.885 – 3.71 0.083 9 175 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.995 0.684 – 1.45 0.976 33 485 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.43 0.805 – 2.64 0.205 15 226 exclusion phecode
760 Back pain Symptoms 0.99 0.945 – 1.04 0.688 1861 23664 exclusion phecode
761 Cervicalgia Symptoms 1.03 0.91 – 1.16 0.669 284 3820 exclusion phecode
764 Sciatica Symptoms 0.966 0.876 – 1.06 0.477 446 5434 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.04 0.907 – 1.19 0.58 222 2565 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.09 0.899 – 1.32 0.384 116 1209 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.868 0.736 – 1.02 0.0898 155 1803 exclusion phecode
771.1 Swelling of limb Symptoms 1.05 0.976 – 1.13 0.194 781 9754 exclusion phecode
772 Symptoms of the muscles Symptoms 0.878 0.726 – 1.06 0.173 112 1269 exclusion phecode
773 Pain in limb Symptoms 1.04 0.978 – 1.1 0.213 1105 13931 exclusion phecode
780 Hypothermia/Chills Symptoms 0.997 0.642 – 1.55 0.987 21 285 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.944 0.834 – 1.07 0.356 277 3591 exclusion phecode
782.3 Edema Symptoms 1.12 0.982 – 1.28 0.0903 252 3038 exclusion phecode
782.6 Pallor and flushing Symptoms 0.878 0.602 – 1.29 0.489 26 319 exclusion phecode
783 Fever of unknown origin Symptoms 1.06 0.982 – 1.15 0.135 670 7181 exclusion phecode
785 Abdominal pain Symptoms 0.994 0.971 – 1.02 0.607 8094 58491 exclusion phecode
788 Syncope and collapse Symptoms 1.03 0.978 – 1.09 0.249 1374 15465 exclusion phecode
789 Nausea and vomiting Symptoms 1.02 0.974 – 1.06 0.473 2385 27018 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 0.859 0.532 – 1.37 0.508 20 259 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.04 0.68 – 1.57 0.867 22 198 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 0.951 0.87 – 1.04 0.273 513 5675 exclusion phecode
791 Gangrene Symptoms 0.994 0.777 – 1.27 0.96 70 704 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1.16 0.838 – 1.61 0.361 39 409 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.726 0.479 – 1.1 0.117 24 281 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 0.889 0.729 – 1.08 0.24 101 1060 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.79 0.954 – 3.71 0.077 12 98 exclusion phecode
797 Shock Symptoms 0.823 0.504 – 1.34 0.414 16 164 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.02 0.473 – 2.21 0.953 8 88 exclusion phecode
798 Malaise and fatigue Symptoms 0.98 0.903 – 1.06 0.624 619 7171 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 0.835 0.695 – 1 0.0513 125 1518 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.02 0.974 – 1.08 0.354 1659 16384 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.04 0.948 – 1.14 0.397 479 4694 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.36 0.921 – 2.02 0.118 29 298 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1 0.905 – 1.11 0.999 422 3979 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.919 0.775 – 1.09 0.327 142 1308 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.971 0.881 – 1.07 0.559 446 4681 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 0.963 0.865 – 1.07 0.491 373 3985 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.11 0.942 – 1.32 0.206 141 1417 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 1.03 0.984 – 1.07 0.213 2204 20980 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 0.989 0.894 – 1.09 0.828 398 4148 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.03 0.976 – 1.08 0.308 1651 15323 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.08 0.924 – 1.27 0.32 164 1605 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.927 0.851 – 1.01 0.0855 571 5687 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.06 0.92 – 1.23 0.402 195 2144 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.23 0.977 – 1.55 0.0772 86 952 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.1 0.948 – 1.27 0.214 195 2044 exclusion phecode
817 Concussion Injuries & Poisonings 1.08 0.716 – 1.62 0.713 25 334 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.981 0.773 – 1.25 0.873 69 750 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.06 0.954 – 1.19 0.262 343 3285 exclusion phecode
823 Torus fracture Injuries & Poisonings 1.01 0.901 – 1.13 0.894 333 3147 exclusion phecode
830 Dislocation Injuries & Poisonings 0.958 0.847 – 1.08 0.492 277 2900 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 1.05 1 – 1.1 0.0361 2121 24744 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.781 0.612 – 0.994 0.0429 74 881 exclusion phecode
840 Sprains and strains Injuries & Poisonings 1.02 0.787 – 1.32 0.874 65 676 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.929 0.868 – 0.996 0.0367 856 10460 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.07 0.746 – 1.53 0.717 32 316 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.02 0.798 – 1.3 0.89 74 914 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.955 0.825 – 1.11 0.538 190 2164 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.06 0.905 – 1.24 0.468 165 1989 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.938 0.865 – 1.02 0.12 630 7480 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.03 0.947 – 1.11 0.522 635 7277 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 0.649 0.309 – 1.3 0.204 10 103 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.07 0.971 – 1.18 0.166 430 4808 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.944 0.68 – 1.31 0.724 40 389 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 0.924 0.57 – 1.5 0.739 20 227 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.08 0.964 – 1.2 0.191 346 3996 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.22 0.817 – 1.86 0.313 23 294 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 1.37 0.599 – 2.67 0.44 4 61 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 0.971 0.883 – 1.07 0.555 448 4677 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.5 0.661 – 3.93 0.331 5 41 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.32 0.736 – 2.41 0.341 10 93 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.08 0.71 – 1.64 0.71 22 290 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.31 0.861 – 2.01 0.199 24 322 exclusion phecode
873 Broken tooth Injuries & Poisonings 0.886 0.643 – 1.22 0.444 44 469 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.55 0.803 – 3.16 0.177 11 139 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 0.955 0.873 – 1.75 0.832 17 207 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 0.905 0.774 – 1.06 0.206 175 1904 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.01 0.934 – 1.1 0.742 633 7100 exclusion phecode
916 Contusion Injuries & Poisonings 1.02 0.896 – 1.17 0.723 230 2512 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.955 0.687 – 1.32 0.778 41 382 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.14 0.891 – 1.46 0.296 71 791 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 1.18 0.873 – 1.6 0.274 46 454 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.06 0.954 – 1.18 0.272 361 4149 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.08 0.817 – 1.44 0.574 49 521 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.19 0.743 – 1.91 0.459 20 202 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.14 0.911 – 1.42 0.248 86 1069 exclusion phecode
947 Urticaria Injuries & Poisonings 0.921 0.73 – 1.16 0.485 76 829 exclusion phecode
949 Allergies, other Injuries & Poisonings 0.871 0.691 – 1.1 0.237 76 853 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.04 0.794 – 1.37 0.767 55 662 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.926 0.696 – 1.23 0.587 53 607 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.03 0.784 – 1.36 0.824 54 635 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 0.828 0.44 – 1.51 0.526 10 88 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.708 0.263 – 1.64 0.413 5 54 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.997 0.965 – 1.03 0.861 3891 45305 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.993 0.959 – 1.03 0.714 3334 38611 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.01 0.815 – 1.26 0.918 93 1190 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.06 0.927 – 1.21 0.404 237 2939 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.804 0.652 – 0.989 0.0383 100 1005 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 0.803 0.649 – 0.992 0.0403 96 998 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.13 0.832 – 1.54 0.434 42 420 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.05 0.756 – 1.46 0.77 39 458 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.03 0.742 – 1.43 0.87 39 460 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.03 0.972 – 1.09 0.306 1175 14434 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.02 0.895 – 1.16 0.768 232 3343 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.25 0.966 – 1.62 0.0884 61 771 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.21 0.892 – 1.66 0.208 48 608 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.843 0.665 – 1.07 0.155 72 871 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.15 0.954 – 1.4 0.138 110 1475 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.01 0.896 – 1.15 0.818 270 3400 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.989 0.656 – 1.51 0.959 25 268 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.01 0.707 – 1.45 0.964 33 377 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.847 0.444 – 1.64 0.591 10 113 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.67 0.937 – 3.11 0.0725 14 171 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.65 0.966 – 3 0.07 14 118 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.06 0.645 – 1.8 0.819 15 120 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.17 1.08 – 1.24 0.445 13 129 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.4 1.04 – 1.91 0.0251 43 548 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.06 0.875 – 1.28 0.558 110 1358 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.21 0.803 – 1.86 0.359 23 283 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.59 0.765 – 1.68 0.209 4 73 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 0.746 0.379 – 1.44 0.364 10 98 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.98 0.674 – 1.43 0.916 30 235 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.31 0.699 – 2.63 0.394 12 122 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.03 0.946 – 1.11 0.527 634 6384 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 0.985 0.903 – 1.07 0.73 552 5667 exclusion phecode
994.2 Sepsis Injuries & Poisonings 0.985 0.903 – 1.07 0.73 552 5667 exclusion phecode
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