Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Age at menopause UK Biobank (UKB) PheWAS analysis

Age at menopause — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID exprsweb-age-at-menopause-ieu-a-1004-dbslmm-ukb-20211120Legacy DBSLMMDBSLMMLarge GWAS

Evaluation cohort: UK Biobank (UKB).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: study-defined normal-range subset.

For this ExPRS, the exclusion sensitivity scan keeps only the study-defined normal-range subset for Age at menopause before rerunning the PheWAS. The preserved release does not include numeric bounds for this trait. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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137 rows visible 15 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 0.999 0.978 – 1.02 0.945 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 0.968 0.93 – 1.01 0.104 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.968 0.893 – 1.05 0.427 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 0.95 0.886 – 1.02 0.153 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.03 0.775 – 1.36 0.863 55 550 all phecode
010 Tuberculosis Infectious Diseases 0.892 0.761 – 1.05 0.158 166 1659 all phecode
038 Septicemia Infectious Diseases 0.999 0.968 – 1.03 0.959 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 0.992 0.924 – 1.06 0.815 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 0.938 0.855 – 1.03 0.174 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 1.01 0.99 – 1.03 0.338 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 0.994 0.958 – 1.03 0.761 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 1 0.953 – 1.06 0.919 1641 16433 all phecode
041.4 E. coli Infectious Diseases 0.995 0.957 – 1.04 0.823 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 0.998 0.901 – 1.1 0.964 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.954 0.772 – 1.18 0.665 95 949 all phecode
054 Herpes simplex Infectious Diseases 0.965 0.837 – 1.11 0.627 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 0.949 0.873 – 1.03 0.223 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 1 0.785 – 1.27 0.999 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 0.894 0.749 – 1.07 0.214 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 0.937 0.824 – 1.07 0.321 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 0.901 0.798 – 1.02 0.0894 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 1 0.907 – 1.11 0.961 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.16 0.979 – 1.38 0.0864 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.12 0.916 – 1.36 0.275 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 0.998 0.935 – 1.07 0.952 1004 10036 all phecode
079 Viral infection Infectious Diseases 0.967 0.93 – 1.01 0.0912 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 1.03 0.797 – 1.32 0.838 64 640 all phecode
080 Postoperative infection Infectious Diseases 1 0.971 – 1.03 0.938 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.01 0.973 – 1.06 0.525 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.931 0.734 – 1.18 0.556 71 709 all phecode
1000 Burns Injuries & Poisonings 0.984 0.904 – 1.07 0.711 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 1.03 0.974 – 1.1 0.272 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 0.975 0.948 – 1 0.068 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.06 0.943 – 1.2 0.321 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 1.03 0.975 – 1.09 0.291 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 1.04 0.912 – 1.18 0.565 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 0.982 0.864 – 1.12 0.776 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 0.989 0.928 – 1.06 0.748 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 0.993 0.971 – 1.02 0.553 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 0.99 0.964 – 1.02 0.471 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.01 0.99 – 1.03 0.311 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 1.08 0.887 – 1.32 0.437 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.06 0.942 – 1.19 0.349 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.07 0.831 – 1.38 0.601 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 0.995 0.964 – 1.03 0.757 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 0.993 0.977 – 1.01 0.379 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.12 0.988 – 1.26 0.0772 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 1.11 0.986 – 1.26 0.0838 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.02 0.798 – 1.29 0.896 74 756 all phecode
110.12 Althete's foot Infectious Diseases 1.06 0.893 – 1.25 0.523 141 1410 all phecode
112 Candidiasis Infectious Diseases 1 0.958 – 1.05 0.925 2126 21275 all phecode
117 Mycoses Infectious Diseases 0.988 0.874 – 1.12 0.847 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 0.996 0.854 – 1.16 0.964 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 1.11 0.889 – 1.38 0.362 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 0.937 0.735 – 1.19 0.596 69 689 all phecode
134 Helminthiases Infectious Diseases 1.08 0.897 – 1.29 0.432 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1 0.823 – 1.22 0.993 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.913 0.791 – 1.05 0.214 205 2050 all phecode
145 Cancer of mouth Neoplasms 1.03 0.948 – 1.11 0.507 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 1.01 0.903 – 1.14 0.829 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.04 0.859 – 1.27 0.668 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 0.95 0.715 – 1.26 0.726 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.955 0.879 – 1.04 0.267 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 0.927 0.814 – 1.06 0.253 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 1.01 0.89 – 1.14 0.894 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.817 0.621 – 1.07 0.147 57 570 all phecode
150 Cancer of esophagus Neoplasms 0.973 0.903 – 1.05 0.464 762 7630 all phecode
151 Cancer of stomach Neoplasms 1.02 0.938 – 1.11 0.618 569 5696 all phecode
153 Colorectal cancer Neoplasms 1 0.973 – 1.03 0.857 4580 45799 all phecode
153.2 Colon cancer Neoplasms 0.991 0.955 – 1.03 0.644 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.05 1.01 – 1.1 0.0264 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.1 0.991 – 1.22 0.0732 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.994 0.844 – 1.17 0.938 158 1580 all phecode
157 Pancreatic cancer Neoplasms 1.03 0.952 – 1.12 0.439 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.991 0.93 – 1.05 0.77 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.01 0.979 – 1.03 0.672 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.956 0.825 – 1.11 0.55 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.02 0.88 – 1.17 0.83 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.03 0.888 – 1.2 0.67 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 1.12 0.865 – 1.44 0.398 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 0.998 0.96 – 1.04 0.924 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 0.998 0.955 – 1.04 0.922 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.963 0.875 – 1.06 0.448 437 4364 all phecode
170.1 Bone cancer Neoplasms 1.09 0.912 – 1.29 0.353 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 0.907 0.812 – 1.01 0.0852 331 3303 all phecode
172 Skin cancer Neoplasms 0.998 0.98 – 1.02 0.822 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.981 0.943 – 1.02 0.35 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 0.982 0.944 – 1.02 0.37 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.999 0.98 – 1.02 0.955 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.01 0.93 – 1.09 0.87 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.905 0.778 – 1.05 0.198 181 1818 all phecode
174 Breast cancer Neoplasms 1.02 0.997 – 1.03 0.105 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 1.01 0.995 – 1.03 0.154 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.01 0.994 – 1.03 0.188 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.21 1 – 1.45 0.0461 115 1148 all phecode
175 Acquired absence of breast Neoplasms 1 0.96 – 1.04 0.942 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 1.02 0.976 – 1.07 0.37 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 0.999 0.884 – 1.13 0.985 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.03 0.981 – 1.07 0.253 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 1.02 0.96 – 1.08 0.563 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 0.995 0.941 – 1.05 0.853 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1 0.94 – 1.07 0.902 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1 0.937 – 1.07 0.96 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.98 0.871 – 1.1 0.739 305 3049 all phecode
185 Cancer of prostate Neoplasms 1.02 0.993 – 1.05 0.155 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 1.06 0.965 – 1.17 0.221 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.04 0.816 – 1.32 0.752 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 1.12 0.99 – 1.26 0.0728 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1 0.827 – 1.22 0.971 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.971 0.941 – 1 0.0711 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.932 0.876 – 0.993 0.0282 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.922 0.865 – 0.982 0.0121 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.09 0.845 – 1.41 0.5 66 660 all phecode
189.2 Cancer of bladder Neoplasms 0.978 0.938 – 1.02 0.302 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.971 0.929 – 1.02 0.196 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.02 0.865 – 1.21 0.778 144 1439 all phecode
190 Cancer of eye Neoplasms 0.98 0.834 – 1.15 0.804 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.985 0.912 – 1.07 0.714 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1.01 0.928 – 1.1 0.79 566 5650 all phecode
191.11 Cancer of brain Neoplasms 0.998 0.913 – 1.09 0.974 525 5240 all phecode
193 Thyroid cancer Neoplasms 1.03 0.925 – 1.16 0.562 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 0.912 0.741 – 1.12 0.383 95 949 all phecode
195 Cancer, suspected or other Neoplasms 0.998 0.983 – 1.01 0.833 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 0.997 0.981 – 1.01 0.731 16267 159497 all phecode
197 Chemotherapy Neoplasms 0.992 0.978 – 1.01 0.273 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 1 0.981 – 1.02 0.9 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.998 0.97 – 1.03 0.883 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1 0.959 – 1.05 0.963 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.02 0.966 – 1.07 0.506 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.03 0.987 – 1.07 0.188 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.964 0.898 – 1.03 0.304 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.05 1 – 1.1 0.0305 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.934 0.804 – 1.08 0.367 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 0.968 0.917 – 1.02 0.246 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 0.914 0.738 – 1.13 0.408 95 950 all phecode
200 Myeloproliferative disease Neoplasms 0.957 0.897 – 1.02 0.186 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 0.918 0.828 – 1.02 0.107 387 3867 all phecode
201 Hodgkin's disease Neoplasms 0.921 0.809 – 1.05 0.214 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.995 0.953 – 1.04 0.818 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.975 0.929 – 1.02 0.312 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 1.02 0.915 – 1.14 0.698 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 1.03 0.949 – 1.13 0.442 581 5824 all phecode
204 Leukemia Neoplasms 1.02 0.973 – 1.08 0.369 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 1.01 0.932 – 1.1 0.746 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.15 0.88 – 1.51 0.301 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1 0.915 – 1.09 0.989 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 1.02 0.926 – 1.12 0.715 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.976 0.873 – 1.09 0.677 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.09 0.915 – 1.29 0.342 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 1.01 0.927 – 1.1 0.815 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 0.995 0.981 – 1.01 0.522 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.01 0.946 – 1.08 0.752 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.98 0.952 – 1.01 0.155 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.04 0.932 – 1.17 0.466 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.11 0.986 – 1.24 0.085 318 3187 all phecode
214 Lipoma Neoplasms 0.988 0.963 – 1.01 0.374 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.991 0.961 – 1.02 0.562 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.01 0.951 – 1.08 0.707 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 1.01 0.985 – 1.03 0.509 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.926 0.852 – 1.01 0.0692 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 0.928 0.851 – 1.01 0.0855 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 1.03 1.01 – 1.05 0.00922 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 1.03 1.01 – 1.05 0.00342 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.947 0.85 – 1.05 0.315 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 1.02 0.967 – 1.08 0.466 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.977 0.853 – 1.12 0.741 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 1 0.852 – 1.17 0.994 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.881 0.755 – 1.03 0.107 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 1.03 0.861 – 1.24 0.737 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.974 0.768 – 1.24 0.83 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.06 0.986 – 1.14 0.113 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.06 0.986 – 1.14 0.116 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.05 0.804 – 1.38 0.702 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.01 0.886 – 1.14 0.934 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.971 0.906 – 1.04 0.411 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.01 0.875 – 1.16 0.895 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.959 0.862 – 1.07 0.437 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.978 0.872 – 1.1 0.706 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.04 0.985 – 1.09 0.161 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.994 0.953 – 1.04 0.763 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.967 0.89 – 1.05 0.426 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.04 0.978 – 1.11 0.208 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.992 0.902 – 1.09 0.866 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.06 0.981 – 1.15 0.139 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.96 0.915 – 1.01 0.0965 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 0.885 0.803 – 0.974 0.0125 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.11 0.902 – 1.38 0.317 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 0.916 0.767 – 1.09 0.331 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 1 0.986 – 1.02 0.775 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.975 0.916 – 1.04 0.425 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.992 0.81 – 1.21 0.935 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1 0.985 – 1.02 0.755 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 0.977 0.866 – 1.1 0.712 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.986 0.857 – 1.13 0.839 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.01 0.872 – 1.16 0.942 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.02 0.922 – 1.13 0.692 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 0.969 0.955 – 0.983 2.8e-05 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.936 0.9 – 0.973 0.000899 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.963 0.843 – 1.1 0.572 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.877 0.696 – 1.1 0.265 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.916 0.835 – 1.01 0.0651 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 0.97 0.821 – 1.14 0.714 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.972 0.957 – 0.987 0.000333 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.773 0.635 – 0.941 0.0102 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.902 0.779 – 1.05 0.171 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.983 0.921 – 1.05 0.611 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 0.946 0.863 – 1.04 0.244 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 0.969 0.897 – 1.05 0.42 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.959 0.847 – 1.09 0.511 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.967 0.876 – 1.07 0.507 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.04 0.873 – 1.23 0.679 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.01 0.9 – 1.12 0.919 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.978 0.925 – 1.03 0.445 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 0.917 0.858 – 0.98 0.011 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.954 0.889 – 1.02 0.183 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.954 0.886 – 1.03 0.213 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.951 0.799 – 1.13 0.571 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.01 0.938 – 1.1 0.732 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.892 0.767 – 1.04 0.14 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.853 0.686 – 1.06 0.15 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.05 0.93 – 1.2 0.407 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.04 0.847 – 1.28 0.7 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.12 0.951 – 1.32 0.175 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.999 0.921 – 1.08 0.973 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.989 0.848 – 1.15 0.886 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.1 0.897 – 1.35 0.36 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.921 0.736 – 1.15 0.473 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.05 0.945 – 1.17 0.356 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.05 0.945 – 1.17 0.356 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.12 0.983 – 1.27 0.0901 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.1 0.953 – 1.26 0.199 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 0.998 0.846 – 1.18 0.977 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.02 0.864 – 1.21 0.801 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.04 0.845 – 1.28 0.706 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 1 0.85 – 1.19 0.962 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.922 0.8 – 1.06 0.267 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 1.08 0.827 – 1.42 0.556 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 0.963 0.897 – 1.03 0.295 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 0.963 0.908 – 1.02 0.218 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.925 0.857 – 0.998 0.043 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.02 0.923 – 1.12 0.728 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.04 0.836 – 1.31 0.703 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.929 0.815 – 1.06 0.268 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 0.935 0.836 – 1.05 0.243 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.995 0.884 – 1.12 0.939 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.01 0.893 – 1.15 0.834 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 0.992 0.854 – 1.15 0.915 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.02 0.839 – 1.25 0.812 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.11 0.876 – 1.42 0.377 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.09 0.929 – 1.28 0.293 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.11 0.929 – 1.32 0.254 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.995 0.984 – 1.01 0.419 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.995 0.984 – 1.01 0.408 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.996 0.984 – 1.01 0.455 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.89 0.678 – 1.17 0.398 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.942 0.802 – 1.11 0.465 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.891 0.773 – 1.03 0.112 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.981 0.949 – 1.01 0.269 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 0.985 0.95 – 1.02 0.413 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.1 0.9 – 1.34 0.357 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.975 0.896 – 1.06 0.547 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.985 0.903 – 1.08 0.742 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.992 0.949 – 1.04 0.729 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.995 0.917 – 1.08 0.897 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 0.92 0.827 – 1.02 0.124 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.02 0.96 – 1.08 0.537 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.989 0.842 – 1.16 0.896 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 0.989 0.966 – 1.01 0.373 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 0.978 0.947 – 1.01 0.173 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1 0.88 – 1.14 0.967 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 0.978 0.932 – 1.03 0.357 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 0.906 0.847 – 0.97 0.00441 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.02 0.967 – 1.08 0.452 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.01 0.954 – 1.08 0.663 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 0.996 0.934 – 1.06 0.901 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 1.26 1.04 – 1.52 0.0179 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 0.994 0.956 – 1.03 0.754 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 1.02 0.927 – 1.13 0.663 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 0.858 0.715 – 1.03 0.0976 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.03 0.967 – 1.11 0.326 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.12 1.01 – 1.25 0.0366 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.956 0.836 – 1.09 0.511 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.01 0.762 – 1.33 0.957 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.981 0.962 – 1 0.0574 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 0.981 0.961 – 1 0.0565 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 1.13 0.907 – 1.41 0.277 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.02 0.789 – 1.32 0.881 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.12 0.983 – 1.27 0.0892 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1.15 1 – 1.33 0.0465 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.08 0.908 – 1.29 0.382 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.05 0.924 – 1.19 0.456 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 0.992 0.969 – 1.02 0.525 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.985 0.961 – 1.01 0.216 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.06 0.962 – 1.17 0.239 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 0.956 0.898 – 1.02 0.151 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 0.966 0.907 – 1.03 0.282 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 0.948 0.88 – 1.02 0.168 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.04 0.894 – 1.21 0.618 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 0.964 0.83 – 1.12 0.635 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 0.889 0.679 – 1.16 0.393 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 0.991 0.84 – 1.17 0.918 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.1 0.844 – 1.44 0.48 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.963 0.775 – 1.2 0.736 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 0.903 0.753 – 1.08 0.271 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.942 0.767 – 1.16 0.567 103 1059 all phecode
284 Aplastic anemia Hematopoietic 0.94 0.851 – 1.04 0.226 435 4357 all phecode
285 Other anemias Hematopoietic 0.987 0.969 – 1.01 0.169 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.991 0.875 – 1.12 0.883 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.03 0.953 – 1.11 0.451 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.07 0.97 – 1.18 0.174 414 4147 all phecode
286 Coagulation defects Hematopoietic 1.04 0.968 – 1.11 0.308 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 1.06 0.967 – 1.17 0.2 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 1.02 0.825 – 1.27 0.83 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.05 0.936 – 1.19 0.381 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.06 0.822 – 1.37 0.657 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.14 0.915 – 1.42 0.245 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.01 0.908 – 1.12 0.894 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.978 0.93 – 1.03 0.376 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.966 0.812 – 1.15 0.698 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 1.15 0.867 – 1.52 0.334 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 0.981 0.931 – 1.03 0.462 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.05 0.949 – 1.16 0.355 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.907 0.726 – 1.13 0.393 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 0.997 0.965 – 1.03 0.873 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 0.993 0.957 – 1.03 0.696 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 0.993 0.958 – 1.03 0.721 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 0.916 0.724 – 1.16 0.463 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1 0.936 – 1.08 0.92 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.03 0.912 – 1.15 0.668 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 0.99 0.951 – 1.03 0.639 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 0.922 0.844 – 1.01 0.073 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.01 0.896 – 1.14 0.855 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 0.903 0.727 – 1.12 0.361 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.997 0.952 – 1.04 0.893 1929 19281 all phecode
290.1 Dementias Mental Disorders 0.959 0.898 – 1.02 0.205 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 0.937 0.848 – 1.03 0.196 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 1.01 0.874 – 1.16 0.911 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.968 0.894 – 1.05 0.421 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.18 0.924 – 1.5 0.186 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.948 0.882 – 1.02 0.138 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.916 0.768 – 1.09 0.327 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.902 0.799 – 1.02 0.0974 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 0.991 0.899 – 1.09 0.856 436 4376 all phecode
292 Neurological disorders Mental Disorders 0.979 0.95 – 1.01 0.177 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.943 0.894 – 0.995 0.0326 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.974 0.84 – 1.13 0.729 190 1907 all phecode
292.3 Memory loss Mental Disorders 1.01 0.936 – 1.09 0.781 696 6978 all phecode
292.4 Altered mental status Mental Disorders 1.01 0.965 – 1.05 0.699 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 0.96 0.854 – 1.08 0.491 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 0.961 0.918 – 1.01 0.0853 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.968 0.903 – 1.04 0.349 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.02 0.954 – 1.1 0.508 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 1.03 0.945 – 1.12 0.503 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 1 0.86 – 1.17 0.96 178 1780 all phecode
295.3 Psychosis Mental Disorders 0.996 0.849 – 1.17 0.961 169 1710 all phecode
296 Mood disorders Mental Disorders 0.985 0.966 – 1 0.0991 12372 123822 all phecode
296.1 Bipolar Mental Disorders 0.96 0.901 – 1.02 0.204 1059 10599 all phecode
296.2 Depression Mental Disorders 0.99 0.971 – 1.01 0.278 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 0.988 0.888 – 1.1 0.828 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.07 0.954 – 1.2 0.248 311 3070 all phecode
300 Anxiety disorders Mental Disorders 0.993 0.969 – 1.02 0.581 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 0.988 0.963 – 1.01 0.367 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 0.889 0.75 – 1.05 0.176 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.942 0.871 – 1.02 0.134 707 7065 all phecode
300.13 Phobia Mental Disorders 1 0.913 – 1.1 0.985 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.925 0.778 – 1.1 0.377 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 0.882 0.67 – 1.16 0.369 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 1.01 0.84 – 1.23 0.878 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.04 0.857 – 1.27 0.679 113 1129 all phecode
301 Personality disorders Mental Disorders 0.985 0.88 – 1.1 0.797 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.855 0.705 – 1.04 0.114 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.986 0.873 – 1.11 0.826 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1 0.911 – 1.1 0.979 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 0.972 0.871 – 1.08 0.607 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 1.03 0.853 – 1.24 0.765 123 1229 all phecode
304 Adjustment reaction Mental Disorders 0.988 0.877 – 1.11 0.841 293 2936 all phecode
305.2 Eating disorder Mental Disorders 1.09 0.874 – 1.35 0.454 90 900 all phecode
306 Other mental disorder Mental Disorders 0.99 0.977 – 1 0.0989 28056 230087 all phecode
306.9 Tension headache Mental Disorders 0.987 0.878 – 1.11 0.828 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 1.05 0.834 – 1.33 0.66 76 770 all phecode
313.3 Autism Mental Disorders 0.964 0.725 – 1.28 0.801 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 1.08 0.97 – 1.21 0.157 351 3517 all phecode
315.1 Learning disorder Mental Disorders 1.02 0.87 – 1.2 0.777 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 1.07 0.862 – 1.33 0.543 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 0.972 0.945 – 1 0.0466 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.07 0.829 – 1.39 0.59 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 0.985 0.967 – 1 0.105 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 0.988 0.967 – 1.01 0.278 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 0.953 0.888 – 1.02 0.186 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 0.98 0.965 – 0.994 0.00635 19359 185465 all phecode
320 Meningitis Neurological 1 0.911 – 1.11 0.939 444 4447 all phecode
323 Encephalitis Neurological 0.929 0.832 – 1.04 0.197 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 0.947 0.75 – 1.2 0.65 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 0.982 0.874 – 1.1 0.765 292 2916 all phecode
327 Sleep disorders Neurological 1.03 0.974 – 1.1 0.271 1164 11659 all phecode
327.3 Sleep apnea Neurological 1 0.97 – 1.03 0.992 4428 44318 all phecode
327.4 Insomnia Neurological 1.1 0.935 – 1.3 0.245 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 1.16 0.968 – 1.39 0.107 136 1390 all phecode
331 Other cerebral degenerations Neurological 0.985 0.927 – 1.05 0.617 1142 11416 all phecode
331.1 Hydrocephalus Neurological 0.933 0.85 – 1.02 0.14 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 0.96 0.869 – 1.06 0.427 430 4298 all phecode
332 Parkinson's disease Neurological 1.03 0.968 – 1.09 0.365 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.04 0.971 – 1.11 0.261 894 8954 all phecode
333.1 Essential tremor Neurological 0.907 0.788 – 1.04 0.173 216 2157 all phecode
333.2 Myoclonus Neurological 1.05 0.854 – 1.29 0.65 96 958 all phecode
333.4 Torsion dystonia Neurological 1.06 0.928 – 1.2 0.409 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 0.992 0.946 – 1.04 0.753 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 1.02 0.848 – 1.24 0.802 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 1.05 0.923 – 1.2 0.449 245 2446 all phecode
335 Multiple sclerosis Neurological 1.04 0.984 – 1.1 0.166 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 1.01 0.89 – 1.15 0.879 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 0.916 0.722 – 1.16 0.473 72 719 all phecode
338 Pain Neurological 1.03 0.955 – 1.11 0.456 768 7692 all phecode
338.1 Acute pain Neurological 1.06 0.956 – 1.18 0.268 394 3937 all phecode
338.2 Chronic pain Neurological 1.01 0.905 – 1.12 0.925 380 3817 all phecode
339 Other headache syndromes Neurological 0.992 0.969 – 1.01 0.475 7819 78241 all phecode
340 Migraine Neurological 1.03 0.988 – 1.07 0.183 2860 28602 all phecode
340.1 Migrain with aura Neurological 0.98 0.853 – 1.13 0.771 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.04 0.918 – 1.19 0.507 252 2535 all phecode
342 Hemiplegia Neurological 0.98 0.929 – 1.03 0.468 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 1.04 0.883 – 1.23 0.632 145 1450 all phecode
344 Other paralytic syndromes Neurological 1.03 0.949 – 1.11 0.504 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.971 0.943 – 1 0.0481 5023 50270 all phecode
345.1 Epilepsy Neurological 1 0.933 – 1.07 0.99 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 1.01 0.916 – 1.11 0.845 439 4385 all phecode
345.12 Partial epilepsy Neurological 1.03 0.906 – 1.16 0.679 277 2776 all phecode
345.3 Convulsions Neurological 0.959 0.918 – 1 0.0602 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1 0.845 – 1.18 0.995 144 1438 all phecode
348 Other conditions of brain Neurological 1.02 0.95 – 1.1 0.542 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.03 0.909 – 1.17 0.618 268 2678 all phecode
348.4 Cerebral cysts Neurological 1.12 0.935 – 1.34 0.22 133 1350 all phecode
348.7 Coma Neurological 1.01 0.909 – 1.13 0.806 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.04 0.908 – 1.18 0.605 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 1.07 0.962 – 1.18 0.226 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.959 0.858 – 1.07 0.464 342 3414 all phecode
350 Abnormal movement Neurological 1.04 0.996 – 1.08 0.0757 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 1.01 0.944 – 1.08 0.741 887 8852 all phecode
350.2 Abnormality of gait Neurological 1.02 0.971 – 1.08 0.391 1596 15969 all phecode
350.3 Lack of coordination Neurological 1.07 0.964 – 1.2 0.195 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.02 0.769 – 1.36 0.883 54 540 all phecode
351 Other peripheral nerve disorders Neurological 0.988 0.97 – 1.01 0.201 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 0.969 0.917 – 1.02 0.264 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.985 0.895 – 1.08 0.761 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 0.993 0.927 – 1.06 0.835 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 1.01 0.947 – 1.07 0.833 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 0.952 0.782 – 1.16 0.624 114 1138 all phecode
353.2 Nerve root lesions Neurological 0.971 0.749 – 1.26 0.822 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.933 0.786 – 1.11 0.428 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 0.96 0.908 – 1.02 0.151 1361 13648 all phecode
358 Myoneural disorders Neurological 1.01 0.872 – 1.16 0.919 211 2109 all phecode
358.1 Myasthenia gravis Neurological 0.995 0.857 – 1.16 0.951 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.878 0.799 – 0.965 0.00703 465 4646 all phecode
359.1 Muscular dystrophies Neurological 0.852 0.71 – 1.02 0.0849 122 1219 all phecode
359.2 Myopathy Neurological 0.895 0.804 – 0.997 0.0444 360 3597 all phecode
360 Disorders of the globe Sense Organs 0.907 0.813 – 1.01 0.0801 337 3367 all phecode
360.2 Progressive myopia Sense Organs 0.872 0.768 – 0.99 0.0346 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 0.977 0.943 – 1.01 0.208 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.969 0.918 – 1.02 0.265 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 1.02 0.808 – 1.28 0.898 68 680 all phecode
362 Other retinal disorders Sense Organs 0.99 0.958 – 1.02 0.561 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.961 0.92 – 1 0.0766 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.961 0.92 – 1 0.0763 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.99 0.845 – 1.16 0.898 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 1 0.82 – 1.22 0.987 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.02 0.953 – 1.1 0.538 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 1.08 0.928 – 1.25 0.327 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.23 0.977 – 1.54 0.0792 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.976 0.812 – 1.17 0.795 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.889 0.759 – 1.04 0.148 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 0.907 0.71 – 1.16 0.437 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.979 0.904 – 1.06 0.613 647 6485 all phecode
364.1 Corneal opacity Sense Organs 1.13 0.916 – 1.4 0.253 90 910 all phecode
364.2 Corneal edema Sense Organs 0.834 0.665 – 1.05 0.117 79 800 all phecode
364.4 Corneal degenerations Sense Organs 1.21 1.04 – 1.39 0.0112 201 2017 all phecode
364.41 Keratoconus Sense Organs 1.15 0.923 – 1.43 0.214 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 0.954 0.829 – 1.1 0.505 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.892 0.727 – 1.09 0.271 100 1000 all phecode
365 Glaucoma Sense Organs 1.03 1 – 1.06 0.0458 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 1.04 0.979 – 1.11 0.195 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.04 0.977 – 1.11 0.212 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.07 0.988 – 1.15 0.0997 698 6996 all phecode
366 Cataract Sense Organs 0.989 0.975 – 1 0.156 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 1.06 0.836 – 1.35 0.624 69 700 all phecode
366.2 Senile cataract Sense Organs 0.975 0.954 – 0.998 0.0317 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 1.04 0.85 – 1.27 0.708 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.995 0.954 – 1.04 0.82 2408 24092 all phecode
367.1 Myopia Sense Organs 1.02 0.959 – 1.08 0.582 1251 12519 all phecode
367.2 Astigmatism Sense Organs 0.982 0.847 – 1.14 0.806 190 1899 all phecode
367.8 Hypermetropia Sense Organs 0.947 0.832 – 1.08 0.406 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 0.96 0.89 – 1.04 0.293 719 7198 all phecode
368 Visual disturbances Sense Organs 1.01 0.976 – 1.05 0.494 2962 29648 all phecode
368.1 Amblyopia Sense Organs 0.963 0.881 – 1.05 0.402 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.01 0.94 – 1.09 0.716 727 7288 all phecode
368.3 Anisometropia Sense Organs 1.06 0.895 – 1.25 0.517 154 1548 all phecode
368.4 Visual field defects Sense Organs 0.961 0.859 – 1.07 0.482 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 1.05 0.965 – 1.14 0.26 612 6115 all phecode
369 Infection of the eye Sense Organs 0.997 0.913 – 1.09 0.943 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 0.842 0.702 – 1.01 0.0645 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 1.07 0.925 – 1.23 0.374 213 2128 all phecode
370 Keratitis Sense Organs 1.02 0.902 – 1.15 0.776 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 1.06 0.889 – 1.25 0.54 141 1408 all phecode
371 Inflammation of the eye Sense Organs 1 0.965 – 1.04 0.926 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.08 0.983 – 1.18 0.11 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 0.997 0.956 – 1.04 0.902 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 1.01 0.941 – 1.09 0.71 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 0.98 0.954 – 1.01 0.156 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 0.952 0.894 – 1.01 0.128 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 0.998 0.952 – 1.05 0.941 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 1 0.958 – 1.05 0.944 2204 22031 all phecode
375.2 Epiphora Sense Organs 1.03 0.962 – 1.1 0.384 898 8969 all phecode
376 Disorders of the orbit Sense Organs 1.06 0.848 – 1.32 0.612 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.988 0.886 – 1.1 0.824 361 3618 all phecode
377.1 Optic atrophy Sense Organs 1.08 0.829 – 1.4 0.583 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.975 0.81 – 1.17 0.791 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.01 0.956 – 1.07 0.733 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.01 0.945 – 1.08 0.735 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.03 0.892 – 1.18 0.715 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 1.09 0.966 – 1.24 0.158 275 2755 all phecode
379 Other disorders of eye Sense Organs 0.988 0.955 – 1.02 0.482 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 1.02 0.962 – 1.08 0.549 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.964 0.919 – 1.01 0.142 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.03 0.803 – 1.31 0.84 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.948 0.855 – 1.05 0.312 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.921 0.786 – 1.08 0.309 169 1690 all phecode
380 Disorders of external ear Sense Organs 0.938 0.866 – 1.02 0.117 642 6413 all phecode
380.1 Otitis externa Sense Organs 1.02 0.928 – 1.12 0.708 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 1.14 1.02 – 1.27 0.0202 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.01 0.969 – 1.06 0.587 2150 21493 all phecode
381.1 Otitis media Sense Organs 1 0.952 – 1.05 0.997 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.956 0.892 – 1.03 0.212 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 0.964 0.83 – 1.12 0.63 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 0.97 0.833 – 1.13 0.695 171 1709 all phecode
381.9 Otorrhea Sense Organs 1.04 0.924 – 1.18 0.487 281 2807 all phecode
382 Otalgia Sense Organs 0.961 0.854 – 1.08 0.511 308 3084 all phecode
383 Otosclerosis Sense Organs 0.958 0.852 – 1.08 0.471 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.02 0.96 – 1.08 0.566 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.01 0.952 – 1.08 0.652 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.945 0.878 – 1.02 0.136 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 0.937 0.862 – 1.02 0.131 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.958 0.839 – 1.09 0.528 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.02 0.968 – 1.07 0.495 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 1.01 0.925 – 1.1 0.863 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 1.07 0.967 – 1.19 0.182 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 1.01 0.934 – 1.08 0.892 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.989 0.96 – 1.02 0.493 4582 45806 all phecode
388 Other disorders of ear Sense Organs 1.02 0.881 – 1.17 0.825 202 2017 all phecode
389 Hearing loss Sense Organs 0.997 0.966 – 1.03 0.838 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 1.03 0.939 – 1.14 0.508 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 0.932 0.845 – 1.03 0.162 450 4497 all phecode
389.4 Tinnitus Sense Organs 1.05 0.959 – 1.15 0.3 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 0.988 0.96 – 1.02 0.435 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 0.997 0.96 – 1.03 0.868 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 0.975 0.921 – 1.03 0.387 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 0.994 0.934 – 1.06 0.845 1058 10566 all phecode
395 Heart valve disorders Circulatory System 0.995 0.964 – 1.03 0.761 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1 0.965 – 1.04 0.91 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.948 0.838 – 1.07 0.392 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.15 0.945 – 1.39 0.167 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.97 0.791 – 1.19 0.774 97 970 all phecode
395.6 Heart valve replaced Circulatory System 1 0.95 – 1.06 0.941 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 1 0.941 – 1.07 0.921 1048 10468 all phecode
401 Hypertension Circulatory System 0.995 0.987 – 1 0.248 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 0.995 0.986 – 1 0.231 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 0.982 0.937 – 1.03 0.442 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 0.946 0.853 – 1.05 0.297 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.99 0.94 – 1.04 0.712 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 1.05 0.883 – 1.24 0.589 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.04 0.984 – 1.09 0.174 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 0.981 0.969 – 0.993 0.00191 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.996 0.967 – 1.02 0.759 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 0.984 0.966 – 1 0.104 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 0.985 0.969 – 1 0.0714 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 0.989 0.975 – 1 0.153 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.999 0.925 – 1.08 0.978 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.98 0.963 – 0.996 0.0169 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.988 0.931 – 1.05 0.681 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 1 0.955 – 1.05 0.929 1823 18228 all phecode
414.2 ASCVD Circulatory System 0.875 0.687 – 1.11 0.28 72 719 all phecode
415 Pulmonary heart disease Circulatory System 0.956 0.927 – 0.986 0.00417 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.942 0.744 – 1.19 0.621 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.932 0.856 – 1.01 0.0992 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 0.933 0.848 – 1.03 0.162 448 4475 all phecode
416 Cardiomegaly Circulatory System 0.988 0.95 – 1.03 0.546 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 0.989 0.977 – 1 0.0782 28599 270106 all phecode
418.1 Precordial pain Circulatory System 0.99 0.956 – 1.02 0.568 3551 35541 all phecode
420 Carditis Circulatory System 0.974 0.931 – 1.02 0.247 2106 21053 all phecode
420.1 Myocarditis Circulatory System 0.997 0.835 – 1.19 0.972 127 1267 all phecode
420.2 Pericarditis Circulatory System 0.988 0.933 – 1.05 0.671 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 0.973 0.846 – 1.12 0.703 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 1 0.83 – 1.21 0.984 113 1129 all phecode
420.3 Endocarditis Circulatory System 0.969 0.898 – 1.05 0.422 719 7194 all phecode
425 Cardiomyopathy Circulatory System 1.02 0.964 – 1.08 0.469 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.03 0.969 – 1.09 0.373 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.966 0.809 – 1.15 0.703 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.1 0.935 – 1.3 0.249 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 0.795 0.607 – 1.04 0.0977 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 1.01 0.983 – 1.03 0.555 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 0.987 0.944 – 1.03 0.553 2114 21162 all phecode
426.21 First degree AV block Circulatory System 0.976 0.915 – 1.04 0.467 986 9867 all phecode
426.23 Second degree AV block Circulatory System 0.903 0.819 – 0.996 0.0406 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.04 0.953 – 1.13 0.411 587 5868 all phecode
426.25 Other heart block Circulatory System 0.997 0.84 – 1.18 0.975 131 1318 all phecode
426.3 Bundle branch block Circulatory System 1.01 0.974 – 1.05 0.613 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 1.05 0.995 – 1.11 0.0735 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 0.983 0.936 – 1.03 0.493 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.02 0.895 – 1.17 0.744 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.2 0.923 – 1.55 0.176 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.988 0.948 – 1.03 0.554 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.988 0.946 – 1.03 0.57 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 0.994 0.981 – 1.01 0.388 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 0.997 0.961 – 1.03 0.859 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.998 0.957 – 1.04 0.936 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.972 0.909 – 1.04 0.398 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 0.997 0.98 – 1.01 0.695 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.993 0.958 – 1.03 0.71 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.04 0.984 – 1.11 0.157 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1 0.897 – 1.12 0.954 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 1.07 0.999 – 1.14 0.0524 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.02 0.955 – 1.09 0.532 952 9541 all phecode
427.6 Premature beats Circulatory System 1.1 1.01 – 1.21 0.0302 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 1.04 0.864 – 1.25 0.688 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 0.989 0.946 – 1.03 0.62 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.989 0.894 – 1.09 0.83 402 4029 all phecode
427.9 Palpitations Circulatory System 0.998 0.965 – 1.03 0.893 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.997 0.97 – 1.03 0.858 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1 0.956 – 1.05 0.985 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 1 0.97 – 1.03 0.994 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.01 0.94 – 1.09 0.709 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 1.15 0.896 – 1.48 0.268 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.01 0.925 – 1.1 0.807 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.04 0.905 – 1.2 0.565 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 0.986 0.94 – 1.03 0.57 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.987 0.92 – 1.06 0.715 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1.01 0.936 – 1.09 0.825 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 0.986 0.868 – 1.12 0.825 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 0.956 0.935 – 0.977 6.15e-05 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.923 0.87 – 0.98 0.00898 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 0.959 0.837 – 1.1 0.55 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.951 0.922 – 0.982 0.00195 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.922 0.877 – 0.969 0.00141 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 0.959 0.923 – 0.996 0.0316 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 0.941 0.9 – 0.984 0.00797 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 0.96 0.866 – 1.06 0.441 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.949 0.896 – 1.01 0.075 1279 12783 all phecode
440 Atherosclerosis Circulatory System 0.956 0.904 – 1.01 0.113 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.962 0.797 – 1.16 0.683 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.982 0.912 – 1.06 0.617 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 0.907 0.803 – 1.02 0.115 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 0.937 0.863 – 1.02 0.126 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.912 0.807 – 1.03 0.139 283 2827 all phecode
442 Other aneurysm Circulatory System 1.01 0.968 – 1.06 0.557 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 0.992 0.94 – 1.05 0.772 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.987 0.922 – 1.06 0.698 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.1 0.898 – 1.35 0.351 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.979 0.839 – 1.14 0.787 169 1696 all phecode
442.4 Arterial dissection Circulatory System 1.33 1.01 – 1.77 0.044 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.03 0.889 – 1.19 0.718 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 0.971 0.94 – 1 0.0847 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 0.95 0.894 – 1.01 0.101 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.904 0.814 – 1 0.0604 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 0.971 0.939 – 1.01 0.0949 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.986 0.947 – 1.03 0.5 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.02 0.953 – 1.09 0.56 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.01 0.925 – 1.1 0.825 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.982 0.914 – 1.06 0.623 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 1.08 0.928 – 1.25 0.332 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 0.943 0.849 – 1.05 0.269 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 0.972 0.85 – 1.11 0.678 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 0.962 0.909 – 1.02 0.18 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 0.937 0.874 – 1 0.066 868 8712 all phecode
448 Disease of capillaries Circulatory System 0.975 0.821 – 1.16 0.778 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.975 0.903 – 1.05 0.527 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.975 0.943 – 1.01 0.126 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.975 0.942 – 1.01 0.142 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 1.01 0.926 – 1.1 0.834 564 5645 all phecode
454 Varicose veins Circulatory System 1 0.981 – 1.02 0.941 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1.01 0.986 – 1.02 0.591 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.986 0.908 – 1.07 0.743 624 6325 all phecode
455 Hemorrhoids Circulatory System 0.998 0.984 – 1.01 0.735 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.96 0.827 – 1.11 0.592 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.04 0.848 – 1.28 0.706 97 967 all phecode
458 Hypotension Circulatory System 0.999 0.972 – 1.03 0.938 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 0.997 0.942 – 1.05 0.905 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 0.936 0.816 – 1.07 0.35 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 1.01 0.972 – 1.04 0.73 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 0.98 0.965 – 0.996 0.0168 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 1.03 0.871 – 1.22 0.72 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 0.98 0.964 – 0.996 0.0144 16103 159422 all phecode
464 Acute sinusitis Respiratory 0.955 0.826 – 1.1 0.527 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.01 0.965 – 1.05 0.745 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 1.05 0.973 – 1.12 0.222 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.925 0.789 – 1.09 0.342 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.998 0.969 – 1.03 0.914 4654 46553 all phecode
471 Nasal polyps Respiratory 1.01 0.977 – 1.05 0.486 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.996 0.932 – 1.06 0.909 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1.01 0.973 – 1.06 0.533 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 0.978 0.804 – 1.19 0.822 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.01 0.882 – 1.15 0.94 264 2647 all phecode
473.4 Voice disturbance Respiratory 1.02 0.956 – 1.08 0.583 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 0.974 0.928 – 1.02 0.298 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 0.976 0.893 – 1.07 0.596 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1 0.941 – 1.07 0.966 1122 11199 all phecode
475 Chronic sinusitis Respiratory 0.992 0.953 – 1.03 0.706 2589 25882 all phecode
476 Allergic rhinitis Respiratory 1 0.942 – 1.07 0.923 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.04 0.994 – 1.08 0.0894 2447 24452 all phecode
478 Throat pain Respiratory 0.962 0.866 – 1.07 0.474 377 3789 all phecode
479 Other upper respiratory disease Respiratory 0.985 0.954 – 1.02 0.364 4074 40737 all phecode
480 Pneumonia Respiratory 0.989 0.969 – 1.01 0.3 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 0.993 0.968 – 1.02 0.589 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 1 0.976 – 1.03 0.828 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 0.891 0.723 – 1.1 0.282 93 929 all phecode
480.2 Viral pneumonia Respiratory 0.893 0.704 – 1.13 0.35 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.917 0.747 – 1.12 0.403 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.925 0.86 – 0.996 0.0376 794 7951 all phecode
481 Influenza Respiratory 0.991 0.886 – 1.11 0.878 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.946 0.816 – 1.1 0.462 193 1930 all phecode
495 Asthma Respiratory 0.984 0.972 – 0.997 0.0149 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 0.942 0.825 – 1.07 0.373 250 2510 all phecode
496 Chronic airway obstruction Respiratory 0.973 0.953 – 0.992 0.0071 10424 101546 all phecode
496.1 Emphysema Respiratory 1 0.952 – 1.05 0.992 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 0.958 0.922 – 0.995 0.0281 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 0.966 0.928 – 1.01 0.0872 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 0.999 0.953 – 1.05 0.967 1885 18859 all phecode
497 Bronchitis Respiratory 0.835 0.767 – 0.908 2.62e-05 626 6267 all phecode
500 Lung disease due to external agents Respiratory 1.01 0.91 – 1.12 0.891 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.875 0.694 – 1.1 0.262 79 784 all phecode
500.2 Pneumoconiosis Respiratory 1.04 0.908 – 1.18 0.59 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.03 0.951 – 1.12 0.47 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.08 1.01 – 1.15 0.0324 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 0.936 0.855 – 1.02 0.147 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.982 0.877 – 1.1 0.759 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.06 0.82 – 1.36 0.669 61 610 all phecode
506 Empyema and pneumothorax Respiratory 0.958 0.901 – 1.02 0.164 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 0.995 0.97 – 1.02 0.717 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.01 0.965 – 1.06 0.663 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.99 0.951 – 1.03 0.629 2599 26031 all phecode
509.1 Respiratory failure Respiratory 0.976 0.933 – 1.02 0.292 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 0.982 0.936 – 1.03 0.459 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 1.17 0.986 – 1.4 0.0724 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.999 0.899 – 1.11 0.985 386 3863 all phecode
510 Other diseases of lung Respiratory 1.05 0.978 – 1.14 0.165 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 1 0.982 – 1.03 0.774 9031 90349 all phecode
512.1 Wheezing Respiratory 1.05 0.915 – 1.21 0.478 220 2196 all phecode
512.2 Painful respiration Respiratory 0.98 0.852 – 1.13 0.771 207 2075 all phecode
512.7 Shortness of breath Respiratory 0.999 0.973 – 1.03 0.95 5842 58498 all phecode
512.8 Cough Respiratory 1.01 0.969 – 1.05 0.718 2866 28642 all phecode
512.9 Other dyspnea Respiratory 0.973 0.909 – 1.04 0.431 914 9124 all phecode
513 Respiratory abnormalities Respiratory 0.99 0.911 – 1.08 0.812 611 6112 all phecode
513.3 Hypoventilation Respiratory 1.18 0.939 – 1.49 0.154 83 830 all phecode
513.4 Hyperventilation Respiratory 0.958 0.848 – 1.08 0.496 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 1.06 0.899 – 1.24 0.513 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 0.994 0.954 – 1.04 0.77 2465 24673 all phecode
516 Abnormal sputum Respiratory 1.01 0.963 – 1.05 0.772 2132 21335 all phecode
516.1 Hemoptysis Respiratory 1 0.957 – 1.05 0.98 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1 0.981 – 1.02 0.83 9366 93681 all phecode
519.2 Respiratory complications Respiratory 0.976 0.87 – 1.1 0.679 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.999 0.978 – 1.02 0.955 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.02 0.905 – 1.14 0.778 303 3049 all phecode
520 Disorders of tooth development Digestive 1.04 0.991 – 1.09 0.114 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.15 0.861 – 1.53 0.351 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 1.05 1 – 1.09 0.0403 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 0.991 0.955 – 1.03 0.624 3016 30245 all phecode
521.1 Dental caries Digestive 0.991 0.954 – 1.03 0.618 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.01 0.962 – 1.06 0.686 1774 17750 all phecode
522.5 Periapical abscess Digestive 0.995 0.937 – 1.06 0.88 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 1.02 0.968 – 1.07 0.478 1681 16812 all phecode
523.1 Gingivitis Digestive 1.2 0.989 – 1.47 0.0644 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.02 0.956 – 1.08 0.614 1165 11650 all phecode
523.31 Acute periodontitis Digestive 1.03 0.952 – 1.12 0.458 666 6667 all phecode
523.32 Chronic periodontitis Digestive 0.999 0.915 – 1.09 0.981 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.04 0.924 – 1.16 0.551 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.973 0.865 – 1.09 0.651 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.97 0.933 – 1.01 0.138 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.95 0.744 – 1.21 0.679 72 720 all phecode
526 Diseases of the jaws Digestive 0.976 0.912 – 1.04 0.481 928 9279 all phecode
526.1 Cysts of the jaws Digestive 1.06 0.947 – 1.19 0.312 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.977 0.749 – 1.27 0.866 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.01 0.885 – 1.16 0.863 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.02 0.89 – 1.17 0.772 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 1.07 0.879 – 1.31 0.487 110 1098 all phecode
526.9 Jaw disease NOS Digestive 0.815 0.712 – 0.933 0.00299 233 2329 all phecode
527 Diseases of the salivary glands Digestive 1.02 0.941 – 1.1 0.655 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.09 0.876 – 1.35 0.445 84 838 all phecode
527.2 Sialoadenitis Digestive 0.964 0.866 – 1.07 0.505 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 1.18 0.909 – 1.54 0.209 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.09 0.911 – 1.31 0.342 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.01 0.975 – 1.04 0.658 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 1.02 0.928 – 1.12 0.684 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.04 0.937 – 1.15 0.461 389 3884 all phecode
528.12 Oral aphthae Digestive 0.958 0.765 – 1.2 0.706 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.25 1.07 – 1.47 0.00463 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 0.956 0.795 – 1.15 0.634 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 0.997 0.807 – 1.23 0.981 94 940 all phecode
528.5 Diseases of lips Digestive 1.01 0.932 – 1.09 0.836 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.01 0.898 – 1.14 0.871 308 3079 all phecode
528.7 Sialolithiasis Digestive 0.949 0.847 – 1.06 0.372 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 0.97 0.914 – 1.03 0.311 1232 12312 all phecode
529.1 Glossitis Digestive 0.975 0.866 – 1.1 0.674 299 2986 all phecode
530 Diseases of esophagus Digestive 0.982 0.971 – 0.993 0.0014 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.982 0.971 – 0.994 0.00271 31253 272429 all phecode
530.11 GERD Digestive 0.98 0.966 – 0.993 0.00314 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 0.985 0.957 – 1.01 0.307 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 0.981 0.961 – 1 0.0569 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.948 0.901 – 0.997 0.0366 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 0.994 0.948 – 1.04 0.819 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 1.04 0.958 – 1.13 0.355 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.885 0.75 – 1.04 0.149 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.952 0.851 – 1.06 0.385 341 3416 all phecode
530.9 Heartburn Digestive 0.991 0.948 – 1.04 0.709 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.961 0.938 – 0.985 0.00148 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.978 0.902 – 1.06 0.595 637 6374 all phecode
531.2 Gastric ulcer Digestive 0.959 0.928 – 0.99 0.0108 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 0.973 0.937 – 1.01 0.15 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 0.948 0.857 – 1.05 0.293 427 4268 all phecode
532 Dysphagia Digestive 0.978 0.954 – 1 0.0951 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 0.991 0.979 – 1 0.16 28078 261548 all phecode
535.1 Acute gastritis Digestive 0.986 0.928 – 1.05 0.638 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 0.995 0.895 – 1.11 0.928 370 3687 all phecode
535.6 Duodenitis Digestive 1.01 0.982 – 1.03 0.676 7592 75928 all phecode
535.8 Other specified gastritis Digestive 0.987 0.965 – 1.01 0.264 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.03 0.854 – 1.24 0.757 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.969 0.853 – 1.1 0.629 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 0.943 0.91 – 0.977 0.00127 3391 33907 all phecode
540 Appendiceal conditions Digestive 0.983 0.947 – 1.02 0.364 3088 30890 all phecode
540.1 Appendicitis Digestive 0.978 0.941 – 1.02 0.253 2895 28963 all phecode
540.11 Acute appendicitis Digestive 0.965 0.927 – 1 0.0857 2601 26019 all phecode
550 Abdominal hernia Digestive 0.993 0.983 – 1 0.154 45429 282640 all phecode
550.1 Inguinal hernia Digestive 1.02 1 – 1.04 0.0193 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 0.981 0.969 – 0.994 0.00361 26494 238953 all phecode
550.3 Femoral hernia Digestive 0.996 0.918 – 1.08 0.915 651 6504 all phecode
550.4 Umbilical hernia Digestive 0.996 0.963 – 1.03 0.82 3705 37072 all phecode
550.5 Ventral hernia Digestive 0.973 0.94 – 1.01 0.13 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 0.989 0.959 – 1.02 0.469 4444 44442 all phecode
555.1 Regional enteritis Digestive 0.984 0.937 – 1.03 0.533 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 0.98 0.945 – 1.02 0.284 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 0.951 0.871 – 1.04 0.266 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 0.982 0.923 – 1.05 0.576 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 1.04 0.961 – 1.12 0.34 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.916 0.811 – 1.03 0.158 299 2987 all phecode
557.1 Celiac disease Digestive 0.828 0.789 – 0.869 1.39e-14 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 0.996 0.98 – 1.01 0.646 15492 155105 all phecode
559 Ileostomy status Digestive 1 0.951 – 1.05 0.983 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.01 0.979 – 1.05 0.472 3936 39337 all phecode
560.1 Paralytic ileus Digestive 1.04 0.952 – 1.14 0.364 523 5231 all phecode
560.2 Impaction of intestine Digestive 0.989 0.872 – 1.12 0.861 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.986 0.918 – 1.06 0.696 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 1.01 0.973 – 1.05 0.634 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 0.986 0.97 – 1 0.0836 15772 157686 all phecode
561.1 Diarrhea Digestive 0.975 0.887 – 1.07 0.596 466 4653 all phecode
561.2 Flatulence Digestive 0.978 0.93 – 1.03 0.376 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 0.978 0.966 – 0.991 0.000831 26714 211692 all phecode
562.1 Diverticulosis Digestive 0.979 0.966 – 0.991 0.00098 26672 211642 all phecode
563 Constipation Digestive 1.01 0.987 – 1.03 0.479 10314 103140 all phecode
564 Functional digestive disorders Digestive 0.988 0.974 – 1 0.0913 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.02 0.993 – 1.05 0.153 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.02 0.966 – 1.07 0.524 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 0.975 0.959 – 0.992 0.00318 15186 151648 all phecode
565 Anal and rectal conditions Digestive 0.986 0.969 – 1 0.0932 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 0.984 0.961 – 1.01 0.202 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 0.968 0.905 – 1.04 0.345 929 9293 all phecode
568 Other disorders of peritoneum Digestive 0.953 0.919 – 0.988 0.00944 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.945 0.911 – 0.981 0.00302 3101 30987 all phecode
569 Other disorders of intestine Digestive 1 0.971 – 1.03 0.909 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.01 0.861 – 1.19 0.872 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 1.02 0.929 – 1.12 0.674 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.01 0.97 – 1.05 0.721 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 0.983 0.936 – 1.03 0.513 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.872 0.723 – 1.05 0.152 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 1.06 0.933 – 1.21 0.367 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.02 0.954 – 1.09 0.595 976 9804 all phecode
571.81 Portal hypertension Digestive 0.969 0.886 – 1.06 0.484 528 5285 all phecode
572 Ascites (non malignant) Digestive 1.03 0.979 – 1.09 0.249 1544 15454 all phecode
573 Other disorders of liver Digestive 0.98 0.929 – 1.03 0.443 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 0.915 0.745 – 1.12 0.399 96 960 all phecode
573.3 Hepatomegaly Digestive 0.967 0.861 – 1.09 0.575 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 0.976 0.911 – 1.05 0.489 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 0.996 0.962 – 1.03 0.842 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.03 0.893 – 1.18 0.716 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 0.968 0.953 – 0.985 0.000138 15607 156123 all phecode
574.1 Cholelithiasis Digestive 0.966 0.949 – 0.984 0.00015 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.959 0.909 – 1.01 0.117 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.963 0.936 – 0.991 0.00879 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 0.965 0.926 – 1 0.0813 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.948 0.912 – 0.986 0.00826 2748 27523 all phecode
575 Other biliary tract disease Digestive 0.988 0.955 – 1.02 0.462 3867 38724 all phecode
575.1 Cholangitis Digestive 0.994 0.905 – 1.09 0.906 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 1.05 0.969 – 1.13 0.251 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.906 0.824 – 0.997 0.0428 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 0.987 0.935 – 1.04 0.636 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 1 0.941 – 1.07 0.922 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.989 0.887 – 1.1 0.845 348 3488 all phecode
577 Diseases of pancreas Digestive 0.972 0.934 – 1.01 0.165 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 0.969 0.926 – 1.01 0.184 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 0.93 0.85 – 1.02 0.114 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.964 0.867 – 1.07 0.497 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 0.997 0.983 – 1.01 0.715 20626 206278 all phecode
578.1 Hematemesis Digestive 0.986 0.941 – 1.03 0.562 1958 19564 all phecode
578.2 Blood in stool Digestive 0.989 0.95 – 1.03 0.593 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 0.997 0.979 – 1.02 0.744 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.996 0.968 – 1.02 0.759 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.01 0.961 – 1.07 0.637 1548 15498 all phecode
579.2 Splenomegaly Digestive 0.999 0.906 – 1.1 0.99 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.02 0.965 – 1.07 0.554 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.968 0.918 – 1.02 0.223 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 0.986 0.925 – 1.05 0.662 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.996 0.784 – 1.27 0.975 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.931 0.779 – 1.11 0.43 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.991 0.924 – 1.06 0.798 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.882 0.803 – 0.969 0.00871 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.981 0.862 – 1.12 0.766 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.971 0.855 – 1.1 0.646 253 2529 all phecode
585 Renal failure Genitourinary 0.986 0.962 – 1.01 0.261 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 0.977 0.947 – 1.01 0.135 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 0.965 0.914 – 1.02 0.189 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.982 0.943 – 1.02 0.368 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 0.996 0.907 – 1.09 0.936 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1 0.969 – 1.04 0.806 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.09 0.948 – 1.26 0.22 208 2089 all phecode
586.11 Small kidney Genitourinary 1.07 0.918 – 1.24 0.394 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 0.974 0.919 – 1.03 0.376 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.19 0.947 – 1.5 0.134 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.03 0.96 – 1.1 0.423 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 0.955 0.859 – 1.06 0.402 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.08 0.87 – 1.34 0.489 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 0.976 0.81 – 1.18 0.802 116 1158 all phecode
590 Pyelonephritis Genitourinary 0.988 0.934 – 1.05 0.678 1328 13285 all phecode
591 Urinary tract infection Genitourinary 1.01 0.992 – 1.03 0.29 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 0.991 0.954 – 1.03 0.625 2966 29661 all phecode
592.1 Cystitis Genitourinary 0.983 0.946 – 1.02 0.368 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 0.889 0.746 – 1.06 0.19 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 0.968 0.904 – 1.04 0.346 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.971 0.854 – 1.1 0.651 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.1 0.94 – 1.29 0.234 165 1662 all phecode
593 Hematuria Genitourinary 1 0.984 – 1.02 0.994 16068 160204 all phecode
594 Urinary calculus Genitourinary 1 0.977 – 1.03 0.85 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 1.02 0.981 – 1.06 0.345 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 0.968 0.899 – 1.04 0.38 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 1.01 0.971 – 1.06 0.543 2401 24024 all phecode
594.8 Renal colic Genitourinary 1 0.959 – 1.05 0.865 2050 20500 all phecode
595 Hydronephrosis Genitourinary 0.994 0.948 – 1.04 0.785 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 1.01 0.985 – 1.03 0.569 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 1.02 0.971 – 1.06 0.489 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 1.01 0.962 – 1.06 0.672 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.982 0.95 – 1.01 0.273 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.991 0.956 – 1.03 0.627 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 0.968 0.771 – 1.22 0.781 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.03 0.997 – 1.07 0.0743 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1 0.892 – 1.13 0.953 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1 0.987 – 1.02 0.835 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 0.841 0.721 – 0.981 0.0276 166 1670 all phecode
599.2 Retention of urine Genitourinary 0.999 0.974 – 1.02 0.939 6718 67168 all phecode
599.3 Dysuria Genitourinary 0.974 0.918 – 1.03 0.394 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 1 0.981 – 1.02 0.833 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 0.991 0.959 – 1.02 0.568 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 0.994 0.814 – 1.21 0.952 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 0.806 0.62 – 1.05 0.106 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 0.99 0.944 – 1.04 0.67 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 1.01 0.989 – 1.03 0.376 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 1.05 0.999 – 1.09 0.0546 2081 20818 all phecode
601.1 Prostatitis Genitourinary 1.04 0.983 – 1.09 0.186 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 1.09 0.956 – 1.24 0.202 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 1.06 0.995 – 1.14 0.0714 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 0.97 0.745 – 1.26 0.819 59 588 all phecode
601.4 Balanoposthitis Genitourinary 0.974 0.861 – 1.1 0.671 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.04 0.924 – 1.17 0.525 303 3019 all phecode
602 Other disorders of prostate Genitourinary 1.04 0.979 – 1.1 0.225 1341 13408 all phecode
603 Other disorders of testis Genitourinary 0.955 0.913 – 0.998 0.0411 2150 21512 all phecode
603.1 Hydrocele Genitourinary 0.944 0.893 – 0.999 0.0462 1339 13402 all phecode
604 Disorders of penis Genitourinary 1.01 0.977 – 1.05 0.494 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.01 0.971 – 1.05 0.609 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 0.979 0.866 – 1.11 0.735 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 0.99 0.952 – 1.03 0.616 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.886 0.772 – 1.02 0.0861 214 2138 all phecode
609.1 Infertility, male Genitourinary 0.949 0.738 – 1.22 0.681 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.882 0.753 – 1.03 0.119 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 1.02 0.983 – 1.07 0.248 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 0.992 0.927 – 1.06 0.817 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 0.943 0.84 – 1.06 0.324 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 0.993 0.882 – 1.12 0.907 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 1.03 0.974 – 1.09 0.306 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.05 0.972 – 1.13 0.217 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.03 0.975 – 1.08 0.319 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 1.11 0.843 – 1.45 0.466 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 1.02 0.969 – 1.08 0.435 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.01 0.948 – 1.09 0.672 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.05 0.975 – 1.12 0.207 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 0.833 0.652 – 1.07 0.145 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 1.03 0.975 – 1.08 0.316 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.02 0.94 – 1.1 0.684 720 7210 all phecode
613.5 Mastodynia Genitourinary 1.3 1.03 – 1.65 0.0294 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.924 0.854 – 1 0.051 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 1.1 0.982 – 1.23 0.0996 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 1.04 0.902 – 1.2 0.591 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.02 0.99 – 1.05 0.218 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.01 0.966 – 1.05 0.775 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.976 0.908 – 1.05 0.501 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.02 0.791 – 1.32 0.879 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.943 0.851 – 1.05 0.264 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.933 0.837 – 1.04 0.219 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.08 0.953 – 1.22 0.234 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.04 1 – 1.09 0.0447 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.04 0.986 – 1.11 0.137 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.997 0.902 – 1.1 0.948 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.04 0.961 – 1.12 0.356 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.05 0.931 – 1.2 0.402 274 2737 all phecode
615 Endometriosis Genitourinary 1.02 0.984 – 1.05 0.316 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.01 0.895 – 1.13 0.921 304 3037 all phecode
618 Genital prolapse Genitourinary 1 0.984 – 1.02 0.748 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 0.996 0.973 – 1.02 0.769 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1 0.973 – 1.03 0.956 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.997 0.911 – 1.09 0.948 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.924 0.853 – 1 0.0522 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 1.02 1 – 1.05 0.0444 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.02 0.942 – 1.1 0.654 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1.07 1.03 – 1.1 0.000499 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.03 0.996 – 1.08 0.0807 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.996 0.948 – 1.05 0.872 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.983 0.929 – 1.04 0.551 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 1.05 0.821 – 1.34 0.701 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 1.06 1 – 1.13 0.0488 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 1.05 1.03 – 1.07 1.16e-06 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 1.05 1.02 – 1.07 7.04e-05 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 1.07 1.03 – 1.11 0.000198 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.08 1.02 – 1.14 0.0119 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 0.941 0.874 – 1.01 0.107 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.96 0.837 – 1.1 0.553 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.946 0.857 – 1.05 0.278 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 1.01 0.986 – 1.04 0.372 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.02 0.981 – 1.06 0.328 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 1 0.943 – 1.06 0.999 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.04 1.02 – 1.06 6.41e-06 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.04 1.02 – 1.06 3.52e-05 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 1.02 0.849 – 1.23 0.816 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.04 1.02 – 1.06 0.000186 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 1.01 0.967 – 1.06 0.575 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 1.03 0.998 – 1.07 0.0622 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 0.995 0.947 – 1.04 0.827 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 1.02 0.865 – 1.21 0.786 159 1587 all phecode
626.8 Infertility, female Genitourinary 0.991 0.937 – 1.05 0.757 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.04 1.02 – 1.06 0.000254 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 1.04 1.01 – 1.06 0.000996 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 1.07 0.918 – 1.24 0.404 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1 0.941 – 1.07 0.972 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 1.06 0.942 – 1.19 0.33 310 3097 all phecode
628 Ovarian cyst Genitourinary 1.03 1 – 1.07 0.0269 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.02 0.986 – 1.05 0.294 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.992 0.934 – 1.05 0.802 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.1 0.985 – 1.23 0.091 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.02 0.977 – 1.07 0.336 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.06 0.985 – 1.13 0.124 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.995 0.94 – 1.05 0.861 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.985 0.944 – 1.03 0.483 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 1.04 0.962 – 1.13 0.302 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.987 0.927 – 1.05 0.677 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 1.07 0.837 – 1.36 0.596 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.942 0.886 – 1 0.0548 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.988 0.878 – 1.11 0.84 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.986 0.861 – 1.13 0.844 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.03 0.872 – 1.21 0.762 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.981 0.926 – 1.04 0.516 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.01 0.965 – 1.05 0.712 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.03 0.805 – 1.31 0.825 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.912 0.808 – 1.03 0.135 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.13 0.941 – 1.36 0.188 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.966 0.835 – 1.12 0.635 193 1922 all phecode
650 Normal delivery Pregnancy Complications 1.02 0.976 – 1.07 0.356 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 0.987 0.885 – 1.1 0.817 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.979 0.932 – 1.03 0.406 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.02 0.966 – 1.08 0.458 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.1 0.874 – 1.39 0.41 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.968 0.938 – 1 0.0506 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.985 0.806 – 1.2 0.88 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.931 0.891 – 0.973 0.00133 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.982 0.898 – 1.07 0.685 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.994 0.965 – 1.02 0.705 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.995 0.955 – 1.04 0.822 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.12 0.955 – 1.3 0.166 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.967 0.852 – 1.1 0.603 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.922 0.726 – 1.17 0.503 63 624 all phecode
679 Complications of in utero procedures Dermatologic 1.1 0.836 – 1.45 0.491 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 0.988 0.964 – 1.01 0.336 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.925 0.848 – 1.01 0.0786 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.07 0.973 – 1.17 0.17 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.986 0.959 – 1.01 0.329 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.987 0.96 – 1.01 0.341 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.988 0.96 – 1.02 0.377 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.04 0.952 – 1.13 0.418 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1 0.95 – 1.06 0.864 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 0.999 0.956 – 1.04 0.952 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 0.933 0.858 – 1.01 0.103 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 1.02 0.917 – 1.14 0.692 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1.02 0.933 – 1.12 0.66 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.961 0.919 – 1 0.0782 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 0.968 0.857 – 1.09 0.605 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 1.06 0.866 – 1.3 0.57 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 0.983 0.946 – 1.02 0.379 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1 0.977 – 1.03 0.785 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.823 0.646 – 1.05 0.113 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.775 0.587 – 1.02 0.0721 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 0.95 0.79 – 1.14 0.588 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 1.08 1.01 – 1.15 0.0276 986 9854 all phecode
694.1 Vitiligo Dermatologic 1.12 0.852 – 1.46 0.423 60 599 all phecode
694.2 Other dyschromia Dermatologic 1.09 1.01 – 1.17 0.0217 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 1.09 0.906 – 1.31 0.365 117 1170 all phecode
695 Erythematous conditions Dermatologic 0.971 0.931 – 1.01 0.177 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 0.953 0.788 – 1.15 0.621 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 1 0.842 – 1.19 0.99 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 0.9 0.691 – 1.17 0.434 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.02 0.805 – 1.29 0.877 73 727 all phecode
695.3 Rosacea Dermatologic 0.979 0.872 – 1.1 0.714 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.02 0.921 – 1.12 0.732 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.968 0.815 – 1.15 0.711 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.03 0.925 – 1.15 0.564 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 0.952 0.885 – 1.03 0.196 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 0.9 0.787 – 1.03 0.119 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 0.912 0.724 – 1.15 0.431 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 1 0.91 – 1.1 0.984 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 0.951 0.91 – 0.994 0.0249 2252 22509 all phecode
696.4 Psoriasis Dermatologic 0.944 0.903 – 0.987 0.0112 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 0.938 0.892 – 0.987 0.0133 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 0.986 0.912 – 1.07 0.731 706 7052 all phecode
697 Sarcoidosis Dermatologic 0.96 0.879 – 1.05 0.358 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 1.01 0.938 – 1.09 0.798 782 7814 all phecode
700 Corns and callosities Dermatologic 1.04 0.924 – 1.18 0.496 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.991 0.962 – 1.02 0.556 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 0.923 0.742 – 1.15 0.469 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.969 0.929 – 1.01 0.147 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 0.987 0.759 – 1.28 0.921 61 610 all phecode
701.4 Keloid scar Dermatologic 1.04 0.913 – 1.19 0.526 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 0.972 0.883 – 1.07 0.558 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 0.852 0.694 – 1.05 0.125 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.993 0.966 – 1.02 0.621 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 0.994 0.955 – 1.04 0.775 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 0.998 0.961 – 1.04 0.899 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 0.997 0.896 – 1.11 0.952 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 0.988 0.925 – 1.06 0.72 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 1.02 0.991 – 1.05 0.187 5267 52727 all phecode
704.1 Alopecia Dermatologic 1.06 0.886 – 1.27 0.518 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.03 0.809 – 1.3 0.831 76 759 all phecode
705 Disorders of sweat glands Dermatologic 1 0.876 – 1.14 0.989 228 2287 all phecode
705.3 Hidradenitis Dermatologic 0.96 0.827 – 1.12 0.596 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 1.02 0.942 – 1.12 0.569 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 1.02 0.996 – 1.04 0.11 8317 83195 all phecode
706.1 Acne Dermatologic 1.02 0.819 – 1.27 0.848 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 1.02 0.995 – 1.04 0.122 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 0.979 0.934 – 1.03 0.38 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 0.97 0.905 – 1.04 0.386 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.985 0.951 – 1.02 0.396 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 0.942 0.86 – 1.03 0.199 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 0.993 0.853 – 1.16 0.93 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.831 0.642 – 1.08 0.161 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.993 0.954 – 1.03 0.711 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.967 0.89 – 1.05 0.434 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 0.995 0.913 – 1.09 0.917 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.02 0.879 – 1.18 0.807 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.95 0.857 – 1.05 0.329 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.09 0.989 – 1.21 0.0827 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.09 0.975 – 1.22 0.131 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.22 0.965 – 1.53 0.0975 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.816 0.689 – 0.967 0.0191 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 0.731 0.568 – 0.94 0.0144 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.02 0.991 – 1.05 0.175 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.03 0.997 – 1.06 0.0774 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1 0.951 – 1.05 0.991 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.937 0.78 – 1.13 0.488 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.99 0.911 – 1.07 0.806 618 6177 all phecode
716 Other arthropathies Musculoskeletal 0.987 0.977 – 0.998 0.0228 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1 0.966 – 1.04 0.986 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.995 0.979 – 1.01 0.587 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 0.985 0.974 – 0.996 0.00659 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.03 0.969 – 1.09 0.352 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 1.02 0.983 – 1.05 0.326 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 0.99 0.968 – 1.01 0.414 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.998 0.97 – 1.03 0.899 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.936 0.809 – 1.08 0.369 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.03 0.928 – 1.15 0.539 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 0.996 0.975 – 1.02 0.715 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.03 0.944 – 1.13 0.481 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.01 0.969 – 1.05 0.703 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.07 0.834 – 1.38 0.587 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.979 0.949 – 1.01 0.181 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 0.974 0.889 – 1.07 0.566 517 5173 all phecode
723.1 Torticollis Musculoskeletal 1.05 0.858 – 1.27 0.66 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 0.982 0.939 – 1.03 0.438 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 0.995 0.899 – 1.1 0.927 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 1 0.904 – 1.11 0.999 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 0.98 0.765 – 1.25 0.873 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 0.978 0.93 – 1.03 0.398 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.986 0.969 – 1 0.101 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 0.986 0.965 – 1.01 0.179 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 0.953 0.854 – 1.06 0.392 334 3336 all phecode
726.3 Bursitis Musculoskeletal 1.07 0.998 – 1.15 0.0579 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.993 0.969 – 1.02 0.549 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.997 0.959 – 1.04 0.899 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 0.908 0.741 – 1.11 0.355 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.999 0.962 – 1.04 0.937 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 1.02 0.934 – 1.11 0.709 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.04 0.935 – 1.16 0.455 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.2 1.01 – 1.42 0.0426 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.948 0.916 – 0.981 0.00197 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.11 1 – 1.23 0.0416 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 0.957 0.926 – 0.99 0.01 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.95 0.917 – 0.983 0.00364 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 1 0.978 – 1.03 0.75 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.03 0.963 – 1.1 0.406 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 1.1 0.899 – 1.34 0.365 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.14 1.01 – 1.29 0.0414 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.12 0.989 – 1.27 0.0746 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 0.938 0.853 – 1.03 0.185 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.02 0.882 – 1.17 0.824 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.78 0.588 – 1.03 0.0852 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.999 0.951 – 1.05 0.966 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 1.04 0.924 – 1.17 0.527 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.04 0.952 – 1.13 0.391 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 0.994 0.832 – 1.19 0.943 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.01 0.951 – 1.07 0.786 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 0.93 0.767 – 1.13 0.457 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 1.02 0.996 – 1.04 0.113 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 1.04 0.892 – 1.21 0.625 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 1.01 0.983 – 1.04 0.436 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.06 1.01 – 1.11 0.0193 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 0.984 0.933 – 1.04 0.548 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.02 0.99 – 1.04 0.245 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.981 0.932 – 1.03 0.451 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.03 0.908 – 1.18 0.612 248 2476 all phecode
737 Curvature of spine Musculoskeletal 1.02 0.957 – 1.08 0.576 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.03 0.966 – 1.1 0.36 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.03 0.984 – 1.08 0.193 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.05 0.995 – 1.11 0.0765 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 1.02 0.931 – 1.12 0.646 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 0.987 0.974 – 0.999 0.0351 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.99 0.975 – 1.01 0.208 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.989 0.968 – 1.01 0.312 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.04 0.933 – 1.16 0.481 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.05 0.967 – 1.14 0.24 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.976 0.958 – 0.995 0.0118 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.984 0.951 – 1.02 0.357 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 0.898 0.733 – 1.1 0.301 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 0.897 0.826 – 0.974 0.00934 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 1.08 0.91 – 1.28 0.386 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 0.987 0.934 – 1.04 0.633 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 1.07 0.888 – 1.3 0.465 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 0.969 0.739 – 1.27 0.821 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.955 0.919 – 0.992 0.0189 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 0.967 0.865 – 1.08 0.563 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.966 0.78 – 1.2 0.751 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 0.978 0.893 – 1.07 0.63 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 0.953 0.91 – 0.997 0.0382 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.947 0.925 – 0.97 7.1e-06 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 0.948 0.924 – 0.973 4.49e-05 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.945 0.919 – 0.971 5.84e-05 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 0.934 0.854 – 1.02 0.137 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 0.869 0.794 – 0.951 0.00229 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.983 0.914 – 1.06 0.64 815 8144 all phecode
745 Pain in joint Musculoskeletal 0.998 0.976 – 1.02 0.89 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.952 0.916 – 0.99 0.0137 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.956 0.919 – 0.996 0.0292 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.971 0.892 – 1.06 0.501 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.02 0.896 – 1.17 0.74 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.94 0.896 – 0.987 0.0125 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.865 0.74 – 1.01 0.0705 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.03 0.781 – 1.37 0.812 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.01 0.891 – 1.14 0.921 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.921 0.852 – 0.996 0.0402 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.882 0.788 – 0.987 0.0292 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.859 0.741 – 0.995 0.0426 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.968 0.868 – 1.08 0.556 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.03 0.903 – 1.18 0.642 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.914 0.753 – 1.11 0.363 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.971 0.921 – 1.02 0.286 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.999 0.924 – 1.08 0.976 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.02 0.929 – 1.12 0.653 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.966 0.838 – 1.11 0.635 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.933 0.868 – 1 0.0631 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.93 0.84 – 1.03 0.157 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.91 0.811 – 1.02 0.109 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.933 0.832 – 1.05 0.233 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 0.904 0.795 – 1.03 0.126 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 0.875 0.759 – 1.01 0.0666 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.988 0.785 – 1.24 0.917 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.05 0.871 – 1.25 0.634 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.994 0.783 – 1.26 0.958 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.1 0.905 – 1.33 0.346 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.917 0.829 – 1.01 0.0929 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.962 0.832 – 1.11 0.603 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.901 0.766 – 1.06 0.205 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.908 0.744 – 1.11 0.344 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.947 0.87 – 1.03 0.2 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.886 0.707 – 1.11 0.295 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.964 0.873 – 1.06 0.461 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.828 0.702 – 0.976 0.0243 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.769 0.594 – 0.996 0.0465 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.996 0.867 – 1.14 0.954 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.06 0.86 – 1.3 0.592 96 959 all phecode
760 Back pain Symptoms 0.967 0.948 – 0.986 0.000793 11126 111353 all phecode
761 Cervicalgia Symptoms 1.04 0.995 – 1.1 0.0773 1791 17901 all phecode
764 Sciatica Symptoms 1.04 0.995 – 1.08 0.0808 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.979 0.922 – 1.04 0.497 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 0.952 0.878 – 1.03 0.234 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.979 0.913 – 1.05 0.551 870 8687 all phecode
771.1 Swelling of limb Symptoms 0.996 0.966 – 1.03 0.797 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 0.961 0.886 – 1.04 0.335 659 6581 all phecode
773 Pain in limb Symptoms 0.97 0.945 – 0.995 0.0213 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 0.821 0.7 – 0.962 0.0146 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.01 0.965 – 1.06 0.625 1870 18715 all phecode
782.3 Edema Symptoms 0.978 0.929 – 1.03 0.394 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 1.01 0.868 – 1.18 0.871 175 1748 all phecode
783 Fever of unknown origin Symptoms 1.03 0.995 – 1.06 0.0928 3911 39105 all phecode
785 Abdominal pain Symptoms 0.983 0.973 – 0.994 0.00173 40080 301686 all phecode
788 Syncope and collapse Symptoms 0.988 0.967 – 1.01 0.264 9069 90813 all phecode
789 Nausea and vomiting Symptoms 0.986 0.968 – 1.01 0.163 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 0.91 0.768 – 1.08 0.275 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 0.944 0.751 – 1.19 0.623 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.03 1 – 1.05 0.037 6357 63635 all phecode
791 Gangrene Symptoms 1.01 0.927 – 1.11 0.786 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1 0.818 – 1.23 0.967 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.05 0.882 – 1.24 0.601 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 0.955 0.876 – 1.04 0.295 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.925 0.77 – 1.11 0.402 120 1198 all phecode
797 Shock Symptoms 1.05 0.888 – 1.25 0.558 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 1.05 0.86 – 1.28 0.628 102 1020 all phecode
798 Malaise and fatigue Symptoms 0.988 0.954 – 1.02 0.51 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 1.06 0.973 – 1.15 0.183 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 0.986 0.962 – 1.01 0.258 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.01 0.965 – 1.06 0.611 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.919 0.786 – 1.07 0.289 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.964 0.923 – 1.01 0.107 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 0.974 0.905 – 1.05 0.489 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.958 0.917 – 1 0.0577 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 0.967 0.921 – 1.01 0.165 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.98 0.908 – 1.06 0.612 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.975 0.954 – 0.998 0.0316 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 0.986 0.938 – 1.04 0.595 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.971 0.943 – 0.999 0.0416 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.992 0.941 – 1.05 0.757 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.98 0.945 – 1.02 0.265 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.945 0.894 – 0.999 0.0463 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 1.05 0.979 – 1.13 0.162 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.98 0.926 – 1.04 0.486 1300 12998 all phecode
817 Concussion Injuries & Poisonings 0.895 0.785 – 1.02 0.101 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.02 0.935 – 1.12 0.631 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.986 0.949 – 1.02 0.464 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 0.966 0.919 – 1.02 0.176 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 0.962 0.92 – 1.01 0.0882 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 1 0.985 – 1.02 0.86 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 0.984 0.899 – 1.08 0.724 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 0.994 0.904 – 1.09 0.893 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.01 0.978 – 1.03 0.69 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.984 0.837 – 1.16 0.849 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.04 0.944 – 1.14 0.459 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.988 0.941 – 1.04 0.619 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.03 0.971 – 1.09 0.338 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.01 0.97 – 1.04 0.734 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.05 1.01 – 1.09 0.0131 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1.06 0.828 – 1.37 0.627 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.01 0.974 – 1.04 0.646 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.886 0.784 – 1 0.0532 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.967 0.838 – 1.12 0.643 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.01 0.975 – 1.05 0.495 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.957 0.834 – 1.1 0.526 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 1.08 0.848 – 1.37 0.542 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 0.994 0.963 – 1.03 0.732 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.05 0.8 – 1.38 0.719 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.11 0.895 – 1.38 0.339 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.923 0.793 – 1.07 0.301 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 1.09 0.992 – 1.2 0.0735 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 1.17 1.02 – 1.34 0.0273 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 0.946 0.806 – 1.11 0.5 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 0.977 0.83 – 1.15 0.781 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.03 0.971 – 1.09 0.348 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 0.974 0.944 – 1.01 0.106 4260 42663 all phecode
916 Contusion Injuries & Poisonings 0.986 0.935 – 1.04 0.62 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.951 0.815 – 1.11 0.521 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.959 0.865 – 1.06 0.421 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.994 0.876 – 1.13 0.928 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.991 0.948 – 1.04 0.701 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.918 0.799 – 1.05 0.224 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.979 0.803 – 1.19 0.834 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.04 0.952 – 1.13 0.395 550 5509 all phecode
947 Urticaria Injuries & Poisonings 0.974 0.874 – 1.09 0.636 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 1.02 0.919 – 1.14 0.688 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1 0.907 – 1.11 0.973 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.13 0.998 – 1.28 0.0538 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.01 0.921 – 1.11 0.826 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 0.885 0.668 – 1.17 0.395 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.959 0.755 – 1.22 0.733 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.994 0.979 – 1.01 0.467 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.997 0.98 – 1.01 0.677 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 0.971 0.878 – 1.07 0.564 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.984 0.918 – 1.06 0.651 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.994 0.893 – 1.11 0.906 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 0.987 0.886 – 1.1 0.81 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1 0.876 – 1.15 0.95 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.09 0.968 – 1.23 0.151 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.12 0.987 – 1.26 0.0791 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.993 0.967 – 1.02 0.579 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.01 0.954 – 1.08 0.648 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.91 0.83 – 0.999 0.0477 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.995 0.898 – 1.1 0.93 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.01 0.921 – 1.11 0.844 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.944 0.867 – 1.03 0.182 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 0.966 0.922 – 1.01 0.146 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.929 0.799 – 1.08 0.335 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.968 0.854 – 1.1 0.613 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.04 0.832 – 1.29 0.742 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 0.912 0.754 – 1.1 0.344 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.993 0.809 – 1.22 0.945 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.06 0.829 – 1.36 0.631 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.95 0.732 – 1.23 0.701 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.02 0.894 – 1.17 0.755 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 0.938 0.868 – 1.01 0.105 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.919 0.798 – 1.06 0.24 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 0.971 0.752 – 1.25 0.819 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.08 0.887 – 1.31 0.445 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.999 0.824 – 1.21 0.995 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.956 0.771 – 1.19 0.685 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.04 1 – 1.08 0.047 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 0.998 0.961 – 1.04 0.897 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 0.998 0.961 – 1.04 0.897 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 1.03 0.982 – 1.09 0.208 1682 19027 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.01 0.918 – 1.1 0.884 500 5799 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.1 0.905 – 1.33 0.34 117 1343 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.22 1.04 – 1.43 0.0147 171 1766 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.15 0.491 – 2.92 0.723 6 74 exclusion phecode
010 Tuberculosis Infectious Diseases 0.709 0.456 – 1.1 0.113 23 263 exclusion phecode
038 Septicemia Infectious Diseases 1.01 0.936 – 1.09 0.778 725 7408 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 0.972 0.81 – 1.17 0.761 134 1367 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 0.995 0.77 – 1.28 0.971 67 665 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.05 0.999 – 1.09 0.0565 2031 22897 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.01 0.917 – 1.11 0.838 444 4933 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.18 1.03 – 1.35 0.0137 233 2545 exclusion phecode
041.4 E. coli Infectious Diseases 1.05 0.964 – 1.15 0.248 551 6795 exclusion phecode
053 Herpes zoster Infectious Diseases 1.04 0.807 – 1.34 0.756 70 930 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.944 0.551 – 1.6 0.823 15 193 exclusion phecode
054 Herpes simplex Infectious Diseases 1.04 0.754 – 1.42 0.825 43 375 exclusion phecode
070 Viral hepatitis Infectious Diseases 0.941 0.75 – 1.18 0.595 83 763 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.31 0.721 – 2.41 0.376 15 129 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 1.13 0.605 – 2.12 0.687 9 124 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 0.981 0.663 – 1.45 0.92 27 253 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 0.795 0.639 – 0.991 0.039 78 740 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 0.838 0.638 – 1.1 0.194 57 820 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 2.25 3.26 – 24.3 0.835 1 5 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.687 0.668 – 0.722 0.978 1 6 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.885 0.764 – 1.02 0.102 193 2034 exclusion phecode
079 Viral infection Infectious Diseases 1.01 0.925 – 1.1 0.82 549 5600 exclusion phecode
079.1 Varicella infection Infectious Diseases 1.28 0.682 – 2.64 0.457 9 70 exclusion phecode
080 Postoperative infection Infectious Diseases 1.06 0.98 – 1.14 0.148 713 8584 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.07 0.964 – 1.18 0.208 412 4337 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.12 0.524 – 1.23 0.731 8 90 exclusion phecode
1000 Burns Injuries & Poisonings 1.01 0.781 – 1.32 0.918 60 687 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 1.02 0.869 – 1.2 0.809 171 1834 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 0.961 0.903 – 1.02 0.213 1074 11906 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.19 0.859 – 1.64 0.289 41 462 exclusion phecode
1005 Other symptoms Injuries & Poisonings 1.12 0.992 – 1.26 0.0656 285 2857 exclusion phecode
1006 Crushing injury Injuries & Poisonings 0.972 0.606 – 1.57 0.904 20 179 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 0.981 0.626 – 1.54 0.932 26 247 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 0.977 0.794 – 1.2 0.826 98 971 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 0.96 0.901 – 1.02 0.212 1066 11800 exclusion phecode
1010 Other tests Injuries & Poisonings 1.05 0.988 – 1.12 0.115 1121 12749 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.01 0.964 – 1.07 0.575 1598 18370 exclusion phecode
1012 Late effect Injuries & Poisonings 0.652 0.404 – 1.03 0.067 20 190 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 0.979 0.714 – 1.34 0.892 41 467 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.46 0.63 – 3.76 0.364 5 55 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 0.976 0.902 – 1.06 0.536 682 8113 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1 0.964 – 1.04 0.912 2825 31585 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.2 0.817 – 1.78 0.34 29 345 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 1.15 0.778 – 1.7 0.478 28 334 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.908 0.438 – 2.05 0.791 8 98 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.09 0.64 – 1.83 0.745 13 139 exclusion phecode
112 Candidiasis Infectious Diseases 1.02 0.923 – 1.13 0.673 417 4523 exclusion phecode
117 Mycoses Infectious Diseases 1.06 0.803 – 1.41 0.662 54 531 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.03 0.729 – 1.45 0.875 36 334 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.744 0.409 – 1.3 0.293 13 120 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 0.884 0.395 – 1.79 0.716 8 95 exclusion phecode
134 Helminthiases Infectious Diseases 1.35 0.939 – 1.96 0.104 30 242 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.26 0.851 – 1.88 0.245 22 193 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.905 0.631 – 1.28 0.571 34 340 exclusion phecode
145 Cancer of mouth Neoplasms 1.15 0.944 – 1.4 0.162 109 999 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.09 0.795 – 1.49 0.587 45 372 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 1.1 0.701 – 1.72 0.664 24 202 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.14 1.02 – 1.21 0.66 8 61 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.14 0.868 – 1.49 0.347 59 595 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.1 0.72 – 1.67 0.65 22 224 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.42 0.811 – 2.58 0.216 15 129 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 0.716 0.378 – 1.32 0.272 11 122 exclusion phecode
150 Cancer of esophagus Neoplasms 1.14 0.912 – 1.43 0.242 82 756 exclusion phecode
151 Cancer of stomach Neoplasms 0.994 0.779 – 1.27 0.963 69 669 exclusion phecode
153 Colorectal cancer Neoplasms 0.984 0.916 – 1.06 0.66 820 8014 exclusion phecode
153.2 Colon cancer Neoplasms 0.976 0.895 – 1.06 0.573 570 5587 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.01 0.908 – 1.13 0.832 361 3548 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.12 0.871 – 1.43 0.382 73 703 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.21 0.768 – 1.93 0.395 18 220 exclusion phecode
157 Pancreatic cancer Neoplasms 1.05 0.868 – 1.28 0.589 115 1244 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.08 0.927 – 1.26 0.323 187 1988 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.03 0.962 – 1.09 0.429 1008 10196 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.807 0.578 – 1.12 0.196 41 326 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.929 0.706 – 1.22 0.593 53 421 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.974 0.739 – 1.29 0.852 57 669 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.929 0.477 – 1.81 0.81 7 107 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.06 0.965 – 1.17 0.22 467 5048 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.02 0.922 – 1.13 0.687 406 4311 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 0.923 0.704 – 1.21 0.552 58 750 exclusion phecode
170.1 Bone cancer Neoplasms 1 0.595 – 1.66 0.998 14 189 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 0.845 0.619 – 1.15 0.277 47 613 exclusion phecode
172 Skin cancer Neoplasms 1.04 0.996 – 1.08 0.0797 2640 26609 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.04 0.949 – 1.13 0.422 530 5557 exclusion phecode
172.11 Melanomas of skin Neoplasms 1.04 0.95 – 1.13 0.422 539 5650 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1.04 0.991 – 1.08 0.113 2128 21283 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.905 0.757 – 1.08 0.272 140 1383 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.979 0.685 – 1.39 0.901 32 387 exclusion phecode
174 Breast cancer Neoplasms 1.04 1.01 – 1.07 0.00389 5158 49314 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1.04 1.01 – 1.07 0.00575 5130 49021 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.05 1.01 – 1.08 0.0034 4830 46312 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.45 1.05 – 1.99 0.0205 38 438 exclusion phecode
175 Acquired absence of breast Neoplasms 1.07 0.996 – 1.14 0.0667 902 9118 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.05 0.97 – 1.15 0.216 612 6319 exclusion phecode
180.1 Cervical cancer Neoplasms 0.989 0.781 – 1.25 0.926 71 927 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.06 0.975 – 1.16 0.166 587 6064 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.99 0.907 – 1.08 0.823 577 5346 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.03 0.935 – 1.13 0.58 486 5412 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.05 0.942 – 1.17 0.377 351 3892 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.05 0.943 – 1.18 0.354 341 3775 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.928 0.753 – 1.14 0.473 100 1201 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.01 0.915 – 1.12 0.83 424 4865 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.901 0.75 – 1.08 0.264 122 1512 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.883 0.731 – 1.07 0.193 116 1443 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.854 0.415 – 1.66 0.616 10 108 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.1 0.959 – 1.25 0.176 241 2547 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.1 0.954 – 1.27 0.185 207 2188 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.846 0.516 – 1.36 0.48 16 167 exclusion phecode
190 Cancer of eye Neoplasms 0.848 0.587 – 1.22 0.365 33 379 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.992 0.811 – 1.21 0.938 100 1093 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.973 0.78 – 1.22 0.809 81 901 exclusion phecode
191.11 Cancer of brain Neoplasms 0.94 0.746 – 1.18 0.591 76 811 exclusion phecode
193 Thyroid cancer Neoplasms 1.11 0.888 – 1.39 0.356 79 905 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.46 0.872 – 2.53 0.14 14 164 exclusion phecode
195 Cancer, suspected or other Neoplasms 0.984 0.947 – 1.02 0.397 2903 31852 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 0.981 0.944 – 1.02 0.34 2775 30410 exclusion phecode
197 Chemotherapy Neoplasms 1.01 0.98 – 1.04 0.511 4735 49725 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.01 0.964 – 1.05 0.759 2195 21920 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.01 0.954 – 1.07 0.767 1377 13575 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.07 0.975 – 1.17 0.151 480 4827 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.04 0.938 – 1.16 0.445 396 4020 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.05 0.964 – 1.15 0.247 524 5348 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.96 0.826 – 1.12 0.599 185 1873 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.14 1.03 – 1.26 0.00954 417 4036 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.07 0.733 – 1.56 0.704 32 356 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 0.918 0.801 – 1.05 0.216 227 2589 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.38 0.801 – 2.4 0.22 13 177 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.01 0.85 – 1.2 0.896 146 1670 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.13 0.795 – 1.62 0.471 29 444 exclusion phecode
201 Hodgkin's disease Neoplasms 0.959 0.649 – 1.42 0.827 31 363 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.05 0.945 – 1.17 0.35 366 3904 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.06 0.946 – 1.2 0.301 311 3167 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.07 0.83 – 1.37 0.609 67 699 exclusion phecode
202.24 Large cell lymphoma Neoplasms 0.919 0.746 – 1.13 0.423 98 998 exclusion phecode
204 Leukemia Neoplasms 0.95 0.838 – 1.08 0.418 260 2686 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 0.95 0.754 – 1.2 0.656 76 848 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.27 0.654 – 2.56 0.462 9 92 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.954 0.745 – 1.22 0.706 65 727 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.01 0.809 – 1.27 0.9 77 813 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.945 0.726 – 1.23 0.668 59 549 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.35 0.899 – 2.06 0.141 25 264 exclusion phecode
204.4 Multiple myeloma Neoplasms 0.927 0.751 – 1.14 0.476 91 913 exclusion phecode
208 Benign neoplasm of colon Neoplasms 0.992 0.956 – 1.03 0.657 3133 35049 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.935 0.806 – 1.08 0.375 190 2053 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.935 0.882 – 0.992 0.0247 1220 13266 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.966 0.704 – 1.32 0.824 44 516 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.23 0.935 – 1.62 0.134 55 656 exclusion phecode
214 Lipoma Neoplasms 0.966 0.903 – 1.03 0.316 922 10710 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.971 0.902 – 1.04 0.427 754 8783 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.99 0.863 – 1.13 0.881 229 2492 exclusion phecode
216 Benign neoplasm of skin Neoplasms 1.04 0.982 – 1.09 0.196 1516 16556 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.976 0.818 – 1.17 0.79 132 1358 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.935 0.776 – 1.13 0.474 121 1300 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 1 0.96 – 1.04 0.997 2523 35009 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 1 0.964 – 1.05 0.839 2543 36078 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.972 0.806 – 1.17 0.762 117 1371 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 1.04 0.942 – 1.14 0.449 453 5269 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.1 0.829 – 1.47 0.499 53 757 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.1 0.691 – 1.76 0.679 22 238 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.975 0.665 – 1.44 0.896 27 277 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.944 0.537 – 1.63 0.829 13 170 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.06 0.916 – 1.22 0.446 201 2016 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.09 0.94 – 1.26 0.251 190 1876 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.983 0.574 – 1.68 0.946 15 197 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.1 0.834 – 1.45 0.489 55 776 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.957 0.827 – 1.11 0.553 200 2135 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.34 0.95 – 1.91 0.0881 34 375 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.926 0.766 – 1.12 0.427 118 1218 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.861 0.642 – 1.15 0.302 51 554 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.14 1.01 – 1.28 0.0325 293 3274 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.951 0.868 – 1.04 0.274 498 5609 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.99 0.838 – 1.17 0.903 146 1855 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.09 0.977 – 1.22 0.12 330 3583 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.07 0.884 – 1.28 0.5 122 1470 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.09 0.944 – 1.25 0.248 221 2239 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.963 0.878 – 1.06 0.425 488 5451 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.922 0.772 – 1.1 0.367 130 1283 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.24 0.826 – 1.89 0.28 23 305 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.99 0.703 – 1.4 0.955 41 412 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.03 0.994 – 1.06 0.117 4173 46923 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.95 0.848 – 1.06 0.376 317 3684 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.01 0.691 – 1.47 0.953 30 283 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.03 0.998 – 1.06 0.0667 3977 45001 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.96 0.764 – 1.21 0.721 77 1006 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.01 0.786 – 1.3 0.931 64 772 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.07 0.83 – 1.37 0.613 65 748 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.11 0.918 – 1.34 0.28 108 1236 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 0.95 0.912 – 0.99 0.0142 2503 30352 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.9 0.808 – 1 0.0545 350 4217 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.967 0.673 – 1.4 0.854 31 401 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.642 0.298 – 1.28 0.207 10 96 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.846 0.661 – 1.08 0.174 67 801 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 0.726 0.45 – 1.14 0.164 22 230 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.949 0.909 – 0.99 0.0161 2250 27623 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.778 0.427 – 1.36 0.353 11 187 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.977 0.599 – 1.59 0.924 20 222 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.899 0.741 – 1.09 0.274 112 1358 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 0.92 0.68 – 1.24 0.576 48 689 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 0.898 0.731 – 1.1 0.301 98 1081 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.17 0.826 – 1.67 0.36 33 352 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.787 0.607 – 1.02 0.0654 63 726 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.85 0.357 – 2 0.651 6 130 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.826 0.554 – 1.22 0.323 29 409 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.899 0.766 – 1.06 0.192 160 1890 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 0.935 0.775 – 1.13 0.473 117 1357 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.922 0.806 – 1.05 0.234 232 2643 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.936 0.813 – 1.08 0.355 212 2406 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.819 0.543 – 1.23 0.319 28 363 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.919 0.738 – 1.15 0.446 83 1150 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.907 0.624 – 1.32 0.602 32 352 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.844 0.528 – 1.34 0.46 21 200 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.938 0.52 – 1 0.757 16 328 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.13 0.698 – 1.85 0.609 16 202 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.06 0.678 – 1.65 0.778 21 324 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.938 0.784 – 1.12 0.484 129 1467 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.1 0.756 – 1.6 0.616 35 424 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.12 0.702 – 1.87 0.607 22 289 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.18 0.696 – 2.03 0.529 14 157 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.98 0.776 – 1.24 0.865 69 831 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.987 0.78 – 1.25 0.912 69 824 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 1.24 0.758 – 2.02 0.374 18 267 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.06 0.605 – 1.86 0.825 14 232 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.741 0.399 – 1.33 0.295 13 184 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.873 0.576 – 1.31 0.504 29 351 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.783 0.543 – 1.12 0.176 35 358 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.09 0.243 – 1.13 0.866 1 48 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.02 0.877 – 1.19 0.795 186 1755 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 0.96 0.842 – 1.1 0.543 243 2730 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.03 0.858 – 1.23 0.779 138 1615 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.903 0.744 – 1.1 0.298 109 1162 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.22 0.77 – 1.95 0.386 18 236 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.04 0.784 – 1.37 0.792 51 593 exclusion phecode
269 Proteinuria Endocrine/metabolic 0.963 0.695 – 1.33 0.817 38 462 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.07 0.782 – 1.47 0.663 43 512 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.967 0.694 – 1.35 0.838 38 454 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 0.978 0.648 – 1.47 0.911 24 325 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1.06 0.655 – 1.7 0.794 20 244 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.09 0.618 – 1.94 0.747 13 131 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.24 0.862 – 1.8 0.225 29 399 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.44 0.96 – 2.17 0.0698 26 359 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.02 0.992 – 1.05 0.159 4907 48027 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.02 0.993 – 1.05 0.14 4899 47963 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.02 0.987 – 1.05 0.264 4555 46146 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.98 0.91 – 2.53 0.953 6 65 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.867 0.55 – 1.36 0.52 23 257 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.757 0.496 – 1.14 0.17 24 376 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.956 0.832 – 1.1 0.523 214 2546 exclusion phecode
274.1 Gout Endocrine/metabolic 0.921 0.775 – 1.09 0.345 140 1641 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.04 0.982 – 1.06 0.943 3 35 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.01 0.795 – 1.28 0.934 75 953 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.02 0.8 – 1.31 0.848 71 901 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.965 0.859 – 1.08 0.552 324 3580 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 1.02 0.802 – 1.3 0.856 79 767 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 0.767 0.564 – 1.04 0.0819 49 685 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.01 0.873 – 1.17 0.908 210 2320 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.07 0.696 – 1.63 0.756 21 258 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.01 0.956 – 1.07 0.665 1284 13708 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1 0.929 – 1.08 0.958 751 8010 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.978 0.61 – 1.57 0.907 26 311 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 0.979 0.88 – 1.09 0.7 380 3927 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.06 0.881 – 1.28 0.518 130 1343 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.01 0.894 – 1.14 0.861 276 3226 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.996 0.854 – 1.16 0.958 175 1904 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1 0.848 – 1.18 0.978 150 1727 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 0.94 0.625 – 1.41 0.757 24 186 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 0.984 0.897 – 1.08 0.729 494 5294 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.03 0.806 – 1.32 0.791 72 715 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 0.967 0.644 – 1.45 0.868 24 293 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.17 0.997 – 1.36 0.0536 163 1902 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.904 0.655 – 1.24 0.529 41 375 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.1 0.771 – 1.57 0.584 29 361 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.917 0.848 – 1 0.776 7 67 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.01 0.958 – 1.06 0.804 1739 22150 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.01 0.957 – 1.06 0.824 1704 21750 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 1.41 0.74 – 3.04 0.241 12 201 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.848 0.457 – 1.49 0.548 14 183 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.28 0.943 – 1.76 0.107 44 470 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.33 0.942 – 1.89 0.098 35 398 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.23 0.778 – 2.22 0.286 25 306 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 0.78 0.48 – 1.24 0.285 20 181 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1 0.95 – 1.06 0.944 1476 16868 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.992 0.941 – 1.05 0.782 1442 16191 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.17 0.918 – 1.5 0.193 70 1049 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.05 0.919 – 1.21 0.448 226 2696 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.07 0.935 – 1.23 0.315 222 2596 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.1 0.936 – 1.29 0.24 166 2005 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.1 0.759 – 1.59 0.596 28 397 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 1.08 0.748 – 1.55 0.689 32 320 exclusion phecode
281.9 Deficiency anemias Hematopoietic 0.992 0.48 – 2.15 0.982 6 127 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 0.882 0.596 – 1.29 0.513 28 275 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 0.826 0.409 – 1.55 0.55 9 86 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.964 0.587 – 1.58 0.879 18 177 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.1 0.703 – 1.73 0.667 25 316 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.35 0.801 – 2.32 0.242 18 233 exclusion phecode
284 Aplastic anemia Hematopoietic 0.955 0.734 – 1.25 0.73 64 645 exclusion phecode
285 Other anemias Hematopoietic 1 0.959 – 1.04 0.989 2346 26300 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.853 0.625 – 1.16 0.299 41 549 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.08 0.913 – 1.29 0.353 139 1506 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.09 0.883 – 1.35 0.415 92 926 exclusion phecode
286 Coagulation defects Hematopoietic 1.05 0.889 – 1.24 0.57 150 1781 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 1 0.805 – 1.25 0.967 89 994 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.774 0.478 – 1.25 0.276 21 237 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.05 0.808 – 1.37 0.707 63 654 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.27 0.48 – 4.07 0.553 3 118 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.993 0.609 – 1.64 0.975 14 137 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.3 0.986 – 1.73 0.0587 52 711 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.942 0.835 – 1.06 0.33 278 2773 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.765 0.505 – 1.15 0.186 25 256 exclusion phecode
287.2 Allergic purpura Hematopoietic 0.964 0.514 – 1.79 0.902 9 73 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 0.968 0.854 – 1.1 0.614 259 2634 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.08 0.868 – 1.35 0.48 83 878 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.685 0.383 – 1.19 0.166 11 136 exclusion phecode
288 Diseases of white blood cells Hematopoietic 0.971 0.905 – 1.04 0.402 867 8476 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 0.982 0.911 – 1.06 0.641 751 7258 exclusion phecode
288.11 Neutropenia Hematopoietic 0.981 0.91 – 1.06 0.609 752 7275 exclusion phecode
288.3 Eosinophilia Hematopoietic 0.679 0.309 – 1.3 0.244 11 116 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.04 0.888 – 1.22 0.611 162 1696 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.14 0.899 – 1.46 0.267 66 686 exclusion phecode
289.4 Lymphadenitis Hematopoietic 0.978 0.89 – 1.08 0.65 467 4971 exclusion phecode
289.5 Diseases of spleen Hematopoietic 0.832 0.663 – 1.04 0.106 81 964 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.04 0.704 – 1.54 0.827 24 316 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.41 0.805 – 2.45 0.209 12 144 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.966 0.857 – 1.09 0.566 295 3392 exclusion phecode
290.1 Dementias Mental Disorders 0.975 0.824 – 1.15 0.766 149 1892 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.989 0.769 – 1.27 0.932 65 939 exclusion phecode
290.16 Vascular dementia Mental Disorders 0.919 0.621 – 1.35 0.659 27 254 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.874 0.706 – 1.08 0.206 90 908 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 2.5 0.82 – 15.7 0.107 4 59 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.06 0.881 – 1.29 0.515 113 1380 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.883 0.539 – 1.33 0.506 25 230 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.966 0.697 – 1.34 0.833 36 465 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.25 0.948 – 1.65 0.107 52 724 exclusion phecode
292 Neurological disorders Mental Disorders 0.991 0.916 – 1.07 0.817 688 7732 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.08 0.946 – 1.24 0.244 225 2577 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 1.03 0.688 – 1.55 0.88 26 305 exclusion phecode
292.3 Memory loss Mental Disorders 0.964 0.781 – 1.19 0.73 98 1180 exclusion phecode
292.4 Altered mental status Mental Disorders 1.04 0.926 – 1.17 0.513 322 3554 exclusion phecode
292.6 Hallucinations Mental Disorders 0.763 0.585 – 0.994 0.0427 56 530 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.13 0.973 – 1.3 0.11 197 2122 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.925 0.785 – 1.09 0.35 158 1699 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.907 0.744 – 1.1 0.327 116 1187 exclusion phecode
295.1 Schizophrenia Mental Disorders 0.888 0.694 – 1.13 0.334 74 712 exclusion phecode
295.2 Paranoid disorders Mental Disorders 0.971 0.629 – 1.5 0.889 26 312 exclusion phecode
295.3 Psychosis Mental Disorders 1.09 0.72 – 1.68 0.668 28 282 exclusion phecode
296 Mood disorders Mental Disorders 0.991 0.949 – 1.03 0.681 2265 26930 exclusion phecode
296.1 Bipolar Mental Disorders 0.91 0.786 – 1.05 0.209 197 2072 exclusion phecode
296.2 Depression Mental Disorders 0.992 0.949 – 1.04 0.73 2146 25774 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.1 0.855 – 1.43 0.438 64 783 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.19 0.878 – 1.62 0.253 44 602 exclusion phecode
300 Anxiety disorders Mental Disorders 0.999 0.945 – 1.06 0.975 1353 15455 exclusion phecode
300.1 Anxiety disorder Mental Disorders 0.999 0.943 – 1.06 0.96 1299 14613 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 0.752 0.505 – 1.1 0.143 31 290 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.956 0.809 – 1.13 0.592 150 1634 exclusion phecode
300.13 Phobia Mental Disorders 1 0.823 – 1.23 0.961 107 1293 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.01 0.644 – 1.6 0.954 19 223 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.64 0.539 – 10.9 0.34 3 83 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 0.923 0.476 – 1.73 0.786 12 181 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.75 0.901 – 3.72 0.0909 9 137 exclusion phecode
301 Personality disorders Mental Disorders 0.973 0.685 – 1.37 0.873 37 512 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.725 0.37 – 1.3 0.278 14 170 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 1.3 0.401 – 1.39 0.554 3 60 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.03 0.823 – 1.28 0.802 87 1087 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 1.07 0.83 – 1.38 0.595 68 830 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.95 0.587 – 1.53 0.824 19 276 exclusion phecode
304 Adjustment reaction Mental Disorders 1.17 0.857 – 1.61 0.31 49 517 exclusion phecode
305.2 Eating disorder Mental Disorders 1.12 1.04 – 1.23 0.602 15 198 exclusion phecode
306 Other mental disorder Mental Disorders 1.04 1.01 – 1.07 0.0207 4097 44263 exclusion phecode
306.9 Tension headache Mental Disorders 1.26 0.969 – 1.65 0.0791 58 752 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 1.07 0.207 – 1.12 0.849 5 93 exclusion phecode
313.3 Autism Mental Disorders 0.972 0.139 – 5.77 0.967 3 49 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.03 0.758 – 1.4 0.831 47 508 exclusion phecode
315.1 Learning disorder Mental Disorders 1.17 0.553 – 2.55 0.639 6 159 exclusion phecode
315.2 Speech and language disorder Mental Disorders 1.7 0.881 – 3.41 0.101 11 140 exclusion phecode
316 Substance addiction and disorders Mental Disorders 0.982 0.888 – 1.09 0.72 408 4492 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.748 0.398 – 1.34 0.329 13 108 exclusion phecode
317 Alcohol-related disorders Mental Disorders 0.985 0.932 – 1.04 0.591 1364 15351 exclusion phecode
317.1 Alcoholism Mental Disorders 0.991 0.929 – 1.06 0.782 1017 11349 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 0.861 0.653 – 1.13 0.276 56 615 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.03 0.986 – 1.07 0.194 2515 28241 exclusion phecode
320 Meningitis Neurological 1.07 0.84 – 1.37 0.561 71 752 exclusion phecode
323 Encephalitis Neurological 0.887 0.694 – 1.13 0.332 71 625 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 1.05 0.638 – 1.73 0.833 15 153 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 0.998 0.763 – 1.31 0.99 52 595 exclusion phecode
327 Sleep disorders Neurological 0.968 0.81 – 1.16 0.718 142 1376 exclusion phecode
327.3 Sleep apnea Neurological 0.948 0.855 – 1.05 0.312 402 4412 exclusion phecode
327.4 Insomnia Neurological 1.29 0.842 – 2.01 0.231 23 315 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.28 0.833 – 2.09 0.254 22 266 exclusion phecode
331 Other cerebral degenerations Neurological 0.973 0.832 – 1.14 0.732 176 1977 exclusion phecode
331.1 Hydrocephalus Neurological 0.922 0.747 – 1.14 0.442 97 1037 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 0.927 0.687 – 1.25 0.611 49 602 exclusion phecode
332 Parkinson's disease Neurological 0.972 0.841 – 1.12 0.697 193 1925 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.975 0.831 – 1.14 0.751 169 1946 exclusion phecode
333.1 Essential tremor Neurological 1.07 0.762 – 1.51 0.682 39 471 exclusion phecode
333.2 Myoclonus Neurological 1.19 0.725 – 1.96 0.487 17 142 exclusion phecode
333.4 Torsion dystonia Neurological 0.885 0.66 – 1.18 0.401 53 579 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 0.99 0.875 – 1.12 0.878 261 2929 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.42 0.935 – 2.17 0.0948 21 193 exclusion phecode
334.2 Anterior horn cell disease Neurological 0.965 0.718 – 1.3 0.809 46 396 exclusion phecode
335 Multiple sclerosis Neurological 1.04 0.928 – 1.17 0.482 324 3301 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.17 0.83 – 1.64 0.356 35 435 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 0.757 0.366 – 1.46 0.398 9 110 exclusion phecode
338 Pain Neurological 1.1 0.919 – 1.33 0.288 124 1638 exclusion phecode
338.1 Acute pain Neurological 1.17 0.918 – 1.49 0.2 73 784 exclusion phecode
338.2 Chronic pain Neurological 1.05 0.793 – 1.38 0.734 52 830 exclusion phecode
339 Other headache syndromes Neurological 0.976 0.924 – 1.03 0.395 1392 16659 exclusion phecode
340 Migraine Neurological 1.01 0.933 – 1.1 0.789 611 7153 exclusion phecode
340.1 Migrain with aura Neurological 0.828 0.587 – 1.15 0.26 34 423 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.924 0.671 – 1.27 0.617 41 528 exclusion phecode
342 Hemiplegia Neurological 1.05 0.906 – 1.21 0.518 198 2477 exclusion phecode
343 Infantile cerebral palsy Neurological 0.914 0.586 – 1.42 0.68 18 199 exclusion phecode
344 Other paralytic syndromes Neurological 1.06 0.864 – 1.31 0.562 96 998 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.988 0.918 – 1.06 0.756 764 8526 exclusion phecode
345.1 Epilepsy Neurological 1 0.824 – 1.22 0.995 114 1399 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 0.987 0.72 – 1.35 0.936 49 680 exclusion phecode
345.12 Partial epilepsy Neurological 1.18 0.875 – 1.61 0.268 44 478 exclusion phecode
345.3 Convulsions Neurological 0.91 0.81 – 1.02 0.111 313 3462 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.779 0.538 – 1.12 0.172 30 291 exclusion phecode
348 Other conditions of brain Neurological 1.14 0.946 – 1.37 0.168 124 1278 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.05 0.788 – 1.41 0.727 49 540 exclusion phecode
348.4 Cerebral cysts Neurological 0.914 0.578 – 1.44 0.688 24 246 exclusion phecode
348.7 Coma Neurological 1.07 0.809 – 1.41 0.638 51 585 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.21 0.853 – 1.73 0.27 35 357 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.18 0.904 – 1.54 0.212 52 659 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.04 0.775 – 1.4 0.792 52 611 exclusion phecode
350 Abnormal movement Neurological 1.04 0.944 – 1.15 0.411 411 4789 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.08 0.901 – 1.29 0.408 134 1585 exclusion phecode
350.2 Abnormality of gait Neurological 1.01 0.887 – 1.14 0.918 251 2980 exclusion phecode
350.3 Lack of coordination Neurological 1.01 0.759 – 1.35 0.925 51 538 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.27 0.633 – 2.48 0.459 9 98 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.01 0.972 – 1.05 0.614 2872 32964 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.05 0.923 – 1.19 0.47 254 2873 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.05 0.855 – 1.29 0.643 103 1115 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.07 0.907 – 1.26 0.415 144 1677 exclusion phecode
353 Nerve root and plexus disorders Neurological 1.06 0.918 – 1.22 0.427 207 2473 exclusion phecode
353.1 Nerve plexus lesions Neurological 1.08 0.703 – 1.64 0.719 26 236 exclusion phecode
353.2 Nerve root lesions Neurological 1.12 0.626 – 2.01 0.683 12 120 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.813 0.478 – 1.36 0.412 17 221 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 0.939 0.803 – 1.1 0.425 171 2042 exclusion phecode
358 Myoneural disorders Neurological 1.06 0.732 – 1.53 0.759 36 421 exclusion phecode
358.1 Myasthenia gravis Neurological 0.947 0.639 – 1.4 0.776 34 390 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.876 0.701 – 1.09 0.236 82 849 exclusion phecode
359.1 Muscular dystrophies Neurological 0.7 0.407 – 1.18 0.168 15 180 exclusion phecode
359.2 Myopathy Neurological 0.962 0.759 – 1.22 0.748 70 695 exclusion phecode
360 Disorders of the globe Sense Organs 0.892 0.689 – 1.15 0.375 61 732 exclusion phecode
360.2 Progressive myopia Sense Organs 0.81 0.602 – 1.08 0.15 48 598 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.89 0.813 – 0.975 0.0117 515 5307 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.757 0.656 – 0.872 0.000111 206 2103 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 1.02 0.863 – 1.1 0.923 8 114 exclusion phecode
362 Other retinal disorders Sense Organs 0.973 0.905 – 1.05 0.46 810 8681 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.967 0.884 – 1.06 0.455 532 5722 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.968 0.885 – 1.06 0.471 531 5707 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.816 0.565 – 1.17 0.258 31 275 exclusion phecode
362.31 Separation of retinal layers Sense Organs 0.973 0.606 – 1.54 0.905 20 189 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.05 0.881 – 1.25 0.591 144 1512 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 1.17 0.784 – 1.76 0.418 25 305 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.59 0.91 – 2.93 0.104 15 160 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.09 0.709 – 1.68 0.673 23 213 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.881 0.631 – 1.23 0.442 38 391 exclusion phecode
363.3 Chorioretinal scars Sense Organs 1.12 0.639 – 1.97 0.683 14 157 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.942 0.798 – 1.11 0.475 151 1454 exclusion phecode
364.1 Corneal opacity Sense Organs 1.13 0.634 – 2.05 0.664 12 155 exclusion phecode
364.2 Corneal edema Sense Organs 1.15 0.695 – 1.9 0.578 16 155 exclusion phecode
364.4 Corneal degenerations Sense Organs 1.16 0.861 – 1.56 0.331 46 382 exclusion phecode
364.41 Keratoconus Sense Organs 2.12 1.1 – 4.5 0.0334 11 90 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.916 0.684 – 1.23 0.552 50 510 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 1.18 0.738 – 1.89 0.486 22 205 exclusion phecode
365 Glaucoma Sense Organs 1.01 0.944 – 1.09 0.71 838 9160 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 1.04 0.898 – 1.21 0.573 188 1964 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 1.06 0.912 – 1.23 0.444 187 1962 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.05 0.906 – 1.23 0.492 190 1873 exclusion phecode
366 Cataract Sense Organs 0.954 0.924 – 0.985 0.00306 4515 38337 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 1.3 0.735 – 2.34 0.348 14 168 exclusion phecode
366.2 Senile cataract Sense Organs 0.939 0.895 – 0.984 0.00833 1905 19770 exclusion phecode
366.3 Traumatic cataract Sense Organs 1.28 0.558 – 3.18 0.539 6 74 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.962 0.879 – 1.05 0.4 521 5221 exclusion phecode
367.1 Myopia Sense Organs 0.966 0.86 – 1.09 0.561 297 2830 exclusion phecode
367.2 Astigmatism Sense Organs 0.955 0.699 – 1.3 0.766 47 441 exclusion phecode
367.8 Hypermetropia Sense Organs 0.895 0.685 – 1.17 0.407 63 668 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.09 0.895 – 1.32 0.39 111 1331 exclusion phecode
368 Visual disturbances Sense Organs 0.93 0.847 – 1.02 0.123 497 5934 exclusion phecode
368.1 Amblyopia Sense Organs 0.955 0.79 – 1.16 0.635 120 1250 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.855 0.706 – 1.03 0.103 126 1261 exclusion phecode
368.3 Anisometropia Sense Organs 1.3 0.864 – 1.96 0.192 23 322 exclusion phecode
368.4 Visual field defects Sense Organs 1.09 0.826 – 1.44 0.536 55 543 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 1.01 0.824 – 1.25 0.889 95 1267 exclusion phecode
369 Infection of the eye Sense Organs 0.916 0.753 – 1.11 0.374 108 1163 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.767 0.525 – 1.12 0.161 30 264 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 1.01 0.742 – 1.39 0.925 42 416 exclusion phecode
370 Keratitis Sense Organs 1.04 0.818 – 1.33 0.727 71 685 exclusion phecode
370.1 Corneal ulcer Sense Organs 1.01 0.715 – 1.44 0.939 35 316 exclusion phecode
371 Inflammation of the eye Sense Organs 0.972 0.892 – 1.06 0.508 577 5870 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.14 0.938 – 1.38 0.188 109 1000 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.945 0.855 – 1.04 0.266 426 4338 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.03 0.871 – 1.23 0.697 149 1609 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.991 0.934 – 1.05 0.769 1202 12922 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.919 0.786 – 1.08 0.291 169 1827 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 1.02 0.927 – 1.13 0.641 435 4764 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.977 0.9 – 1.06 0.58 632 6135 exclusion phecode
375.2 Epiphora Sense Organs 1.03 0.899 – 1.18 0.665 234 2433 exclusion phecode
376 Disorders of the orbit Sense Organs 0.968 0.558 – 1.67 0.904 15 188 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.985 0.774 – 1.25 0.901 71 840 exclusion phecode
377.1 Optic atrophy Sense Organs 1.01 0.535 – 1.83 0.979 10 109 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.92 0.605 – 1.4 0.686 24 291 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.926 0.808 – 1.06 0.266 234 2600 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.916 0.776 – 1.08 0.298 154 1776 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.96 0.629 – 1.46 0.843 25 259 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.07 0.814 – 1.42 0.614 60 533 exclusion phecode
379 Other disorders of eye Sense Organs 0.941 0.873 – 1.01 0.114 741 8062 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 1.02 0.902 – 1.16 0.715 252 2905 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.909 0.818 – 1.01 0.0766 377 4140 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 0.989 0.581 – 1.63 0.966 15 161 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.03 0.822 – 1.3 0.768 81 741 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.875 0.594 – 1.27 0.479 30 331 exclusion phecode
380 Disorders of external ear Sense Organs 0.905 0.732 – 1.12 0.345 96 1174 exclusion phecode
380.1 Otitis externa Sense Organs 0.829 0.653 – 1.05 0.117 71 923 exclusion phecode
380.4 Impacted cerumen Sense Organs 1.21 0.943 – 1.55 0.129 70 753 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.17 1.06 – 1.3 0.00306 374 4138 exclusion phecode
381.1 Otitis media Sense Organs 1.14 1.01 – 1.28 0.0343 294 3351 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.18 0.992 – 1.4 0.0601 136 1597 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.95 0.699 – 1.29 0.738 46 412 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 1.14 0.734 – 1.79 0.549 23 307 exclusion phecode
381.9 Otorrhea Sense Organs 1.1 0.832 – 1.45 0.498 55 518 exclusion phecode
382 Otalgia Sense Organs 0.924 0.697 – 1.22 0.571 52 635 exclusion phecode
383 Otosclerosis Sense Organs 0.845 0.651 – 1.1 0.198 62 730 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.03 0.9 – 1.18 0.665 229 2494 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.02 0.874 – 1.18 0.832 188 2026 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.962 0.807 – 1.15 0.666 130 1405 exclusion phecode
385.3 Cholesteatoma Sense Organs 1.06 0.864 – 1.3 0.58 100 1018 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.941 0.689 – 1.28 0.69 46 537 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.05 0.934 – 1.17 0.435 328 3930 exclusion phecode
386.1 Meniere's disease Sense Organs 0.944 0.771 – 1.16 0.571 104 1399 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 1.37 1.09 – 1.73 0.00663 80 842 exclusion phecode
386.3 Labyrinthitis Sense Organs 0.97 0.814 – 1.15 0.727 138 1628 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.956 0.888 – 1.03 0.229 758 8897 exclusion phecode
388 Other disorders of ear Sense Organs 1.11 0.794 – 1.56 0.531 36 422 exclusion phecode
389 Hearing loss Sense Organs 1.02 0.942 – 1.1 0.635 685 7677 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 1.03 0.814 – 1.3 0.82 77 794 exclusion phecode
389.2 Conductive hearing loss Sense Organs 0.988 0.782 – 1.25 0.916 78 920 exclusion phecode
389.4 Tinnitus Sense Organs 1.19 0.947 – 1.5 0.132 84 982 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.01 0.94 – 1.09 0.732 742 8035 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.01 0.917 – 1.11 0.88 467 5168 exclusion phecode
394.3 Aortic valve disease Circulatory System 1 0.867 – 1.16 0.96 181 1910 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 0.945 0.804 – 1.11 0.49 160 1909 exclusion phecode
395 Heart valve disorders Circulatory System 1.04 0.959 – 1.13 0.338 632 6815 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.04 0.945 – 1.15 0.405 439 4900 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.945 0.699 – 1.28 0.711 42 407 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.26 0.753 – 2.11 0.35 13 180 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.35 0.795 – 2.32 0.253 13 130 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.05 0.916 – 1.21 0.46 215 2071 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.11 0.969 – 1.27 0.131 243 2670 exclusion phecode
401 Hypertension Circulatory System 0.999 0.952 – 1.06 0.937 12363 54260 exclusion phecode
401.1 Essential hypertension Circulatory System 0.999 0.951 – 1.06 0.894 12336 54260 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.03 0.905 – 1.17 0.643 248 2895 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 0.938 0.662 – 1.32 0.706 36 410 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.04 0.905 – 1.2 0.555 212 2519 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.22 0.703 – 2.2 0.459 13 200 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.02 0.888 – 1.16 0.82 232 2672 exclusion phecode
411 Ischemic Heart Disease Circulatory System 0.992 0.958 – 1.03 0.631 3571 38829 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.999 0.921 – 1.08 0.987 618 7073 exclusion phecode
411.2 Myocardial infarction Circulatory System 0.999 0.938 – 1.06 0.985 1044 11600 exclusion phecode
411.3 Angina pectoris Circulatory System 0.993 0.948 – 1.04 0.764 1933 23334 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 0.987 0.94 – 1.04 0.591 1741 20195 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.988 0.812 – 1.2 0.903 104 1050 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.996 0.944 – 1.05 0.873 1483 18282 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.07 0.88 – 1.3 0.504 111 1290 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.02 0.883 – 1.19 0.744 193 2033 exclusion phecode
414.2 ASCVD Circulatory System 0.828 0.199 – 3.27 0.712 4 96 exclusion phecode
415 Pulmonary heart disease Circulatory System 0.941 0.872 – 1.02 0.12 733 8057 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.03 0.669 – 1.58 0.881 22 157 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.948 0.766 – 1.17 0.62 99 1135 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.01 0.797 – 1.28 0.94 80 910 exclusion phecode
416 Cardiomegaly Circulatory System 0.998 0.891 – 1.12 0.971 318 3555 exclusion phecode
418 Nonspecific chest pain Circulatory System 0.99 0.961 – 1.02 0.516 4675 52910 exclusion phecode
418.1 Precordial pain Circulatory System 1.02 0.936 – 1.11 0.646 540 6983 exclusion phecode
420 Carditis Circulatory System 0.999 0.887 – 1.13 0.99 294 3169 exclusion phecode
420.1 Myocarditis Circulatory System 1.03 0.95 – 1.13 0.91 14 142 exclusion phecode
420.2 Pericarditis Circulatory System 1.01 0.86 – 1.18 0.928 170 1893 exclusion phecode
420.21 Acute pericarditis Circulatory System 0.798 0.517 – 1.23 0.293 25 253 exclusion phecode
420.22 Chronic pericarditis Circulatory System 0.876 0.433 – 1.57 0.659 11 155 exclusion phecode
420.3 Endocarditis Circulatory System 0.996 0.824 – 1.2 0.966 119 1224 exclusion phecode
425 Cardiomyopathy Circulatory System 1.06 0.904 – 1.25 0.465 163 1649 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.04 0.882 – 1.23 0.641 158 1610 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.02 0.634 – 1.68 0.922 18 171 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.19 0.792 – 1.78 0.394 27 219 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.02 0.995 – 1.11 0.975 1 11 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.04 0.967 – 1.11 0.305 841 9675 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 0.984 0.858 – 1.13 0.821 219 2511 exclusion phecode
426.21 First degree AV block Circulatory System 0.874 0.703 – 1.08 0.216 89 1073 exclusion phecode
426.23 Second degree AV block Circulatory System 1.02 0.76 – 1.37 0.9 51 504 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1.21 0.943 – 1.56 0.129 63 752 exclusion phecode
426.25 Other heart block Circulatory System 1.3 0.736 – 2.3 0.335 12 177 exclusion phecode
426.3 Bundle branch block Circulatory System 1.03 0.934 – 1.14 0.547 427 4982 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.06 0.9 – 1.25 0.477 152 1845 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.02 0.897 – 1.15 0.792 265 2968 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.802 0.563 – 1.14 0.207 34 353 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 0.865 0.361 – 1.87 0.663 7 99 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.06 0.937 – 1.2 0.353 265 3118 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.05 0.928 – 1.2 0.41 248 2925 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 0.978 0.945 – 1.01 0.194 3580 38263 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.04 0.943 – 1.14 0.468 472 5581 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.02 0.926 – 1.13 0.637 398 4714 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.09 0.867 – 1.37 0.455 76 923 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 0.98 0.934 – 1.03 0.393 1854 20121 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.921 0.832 – 1.02 0.109 417 4570 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.09 0.916 – 1.3 0.318 132 1457 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.05 0.632 – 1.76 0.846 16 256 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.11 0.92 – 1.33 0.277 119 1296 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.04 0.87 – 1.23 0.696 141 1740 exclusion phecode
427.6 Premature beats Circulatory System 1.28 1.01 – 1.61 0.0377 80 810 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1.35 0.835 – 2.26 0.211 15 187 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.01 0.908 – 1.12 0.864 378 4175 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.972 0.765 – 1.23 0.813 68 734 exclusion phecode
427.9 Palpitations Circulatory System 0.964 0.898 – 1.03 0.302 842 9275 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.08 0.996 – 1.17 0.0622 614 6761 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.13 0.995 – 1.29 0.0586 242 2744 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.09 0.994 – 1.2 0.0664 459 5052 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.07 0.883 – 1.3 0.482 109 1347 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.17 0.359 – 3.69 0.744 3 43 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.15 0.906 – 1.45 0.247 73 955 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 0.937 0.659 – 1.32 0.704 36 385 exclusion phecode
430 Intracranial hemorrhage Circulatory System 0.962 0.86 – 1.08 0.504 326 3460 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.986 0.852 – 1.14 0.853 185 2007 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 0.974 0.805 – 1.18 0.78 124 1294 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1 0.657 – 1.54 0.987 26 341 exclusion phecode
433 Cerebrovascular disease Circulatory System 0.981 0.927 – 1.04 0.515 1288 14375 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.966 0.813 – 1.15 0.693 145 1613 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 0.95 0.673 – 1.34 0.762 39 374 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1 0.917 – 1.09 0.976 536 6141 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.03 0.897 – 1.18 0.669 217 2393 exclusion phecode
433.3 Cerebral ischemia Circulatory System 0.95 0.862 – 1.05 0.299 443 5044 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 0.94 0.84 – 1.05 0.279 324 3670 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 0.895 0.728 – 1.1 0.289 98 1038 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.08 0.921 – 1.28 0.329 158 2107 exclusion phecode
440 Atherosclerosis Circulatory System 1.06 0.889 – 1.26 0.522 139 1544 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.939 0.515 – 1.65 0.818 16 135 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.03 0.801 – 1.33 0.813 65 713 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.11 0.818 – 1.5 0.498 46 485 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 0.971 0.808 – 1.16 0.746 120 1405 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1 0.771 – 1.31 0.978 56 631 exclusion phecode
442 Other aneurysm Circulatory System 0.903 0.773 – 1.05 0.194 172 1782 exclusion phecode
442.1 Aortic aneurysm Circulatory System 0.894 0.735 – 1.09 0.255 112 1126 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.859 0.636 – 1.16 0.31 50 518 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.06 1.03 – 1.26 0.888 4 39 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.888 0.565 – 1.39 0.587 17 181 exclusion phecode
442.4 Arterial dissection Circulatory System 2.04 0.946 – 5.42 0.0839 7 57 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 0.713 0.493 – 1.02 0.0615 32 402 exclusion phecode
443 Peripheral vascular disease Circulatory System 0.894 0.819 – 0.977 0.0128 548 6209 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 0.931 0.825 – 1.05 0.246 286 3092 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.741 0.511 – 1.07 0.102 31 320 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 0.898 0.821 – 0.983 0.019 525 5971 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.899 0.79 – 1.02 0.107 245 3002 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 0.897 0.724 – 1.11 0.309 95 1071 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.922 0.671 – 1.26 0.607 44 518 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1 0.856 – 1.17 0.979 174 1901 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.844 0.576 – 1.23 0.367 33 318 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.15 0.931 – 1.43 0.187 92 1145 exclusion phecode
446.9 Arteritis NOS Circulatory System 0.704 0.501 – 0.983 0.0371 42 473 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 0.944 0.789 – 1.13 0.523 139 1604 exclusion phecode
447.1 Stricture of artery Circulatory System 0.966 0.747 – 1.25 0.79 68 907 exclusion phecode
448 Disease of capillaries Circulatory System 0.947 0.681 – 1.31 0.739 37 347 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.939 0.791 – 1.11 0.471 146 1693 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.944 0.869 – 1.03 0.171 627 6968 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.967 0.887 – 1.05 0.449 570 6396 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 0.893 0.721 – 1.1 0.292 102 1022 exclusion phecode
454 Varicose veins Circulatory System 0.983 0.943 – 1.02 0.403 2536 26736 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 0.985 0.948 – 1.02 0.462 2772 28947 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.975 0.807 – 1.18 0.788 124 1164 exclusion phecode
455 Hemorrhoids Circulatory System 1 0.969 – 1.03 0.959 3991 45140 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.08 0.733 – 1.59 0.699 26 300 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.19 1.13 – 1.29 0.371 18 161 exclusion phecode
458 Hypotension Circulatory System 0.978 0.916 – 1.04 0.51 970 11040 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 0.902 0.779 – 1.04 0.163 195 2278 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.01 0.722 – 1.41 0.949 37 380 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.01 0.925 – 1.1 0.877 579 6693 exclusion phecode
459 Other disorders of circulatory system Circulatory System 0.967 0.929 – 1.01 0.103 2551 29966 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.39 0.907 – 2.14 0.114 21 234 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 0.963 0.924 – 1 0.0652 2528 29682 exclusion phecode
464 Acute sinusitis Respiratory 0.881 0.609 – 1.26 0.475 28 453 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.04 0.942 – 1.15 0.429 418 4778 exclusion phecode
465.2 Acute pharyngitis Respiratory 1.1 0.93 – 1.3 0.263 152 1743 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 1 0.693 – 1.45 0.991 30 352 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.982 0.898 – 1.07 0.695 513 5953 exclusion phecode
471 Nasal polyps Respiratory 0.963 0.873 – 1.06 0.454 428 4105 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.996 0.836 – 1.18 0.961 145 1656 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.06 0.96 – 1.17 0.251 420 4899 exclusion phecode
473.1 Chronic laryngitis Respiratory 0.866 0.544 – 1.36 0.523 21 197 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.32 0.916 – 1.91 0.123 31 502 exclusion phecode
473.4 Voice disturbance Respiratory 0.975 0.839 – 1.13 0.734 183 2341 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 0.938 0.808 – 1.09 0.399 187 2340 exclusion phecode
474.1 Acute tonsillitis Respiratory 0.772 0.577 – 1.02 0.0711 56 722 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.1 0.928 – 1.31 0.267 140 1597 exclusion phecode
475 Chronic sinusitis Respiratory 1.03 0.929 – 1.13 0.615 431 5120 exclusion phecode
476 Allergic rhinitis Respiratory 0.982 0.846 – 1.14 0.811 185 1965 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.09 0.976 – 1.21 0.129 363 3957 exclusion phecode
478 Throat pain Respiratory 1.01 0.807 – 1.27 0.92 84 808 exclusion phecode
479 Other upper respiratory disease Respiratory 0.928 0.852 – 1.01 0.0842 589 6716 exclusion phecode
480 Pneumonia Respiratory 1.02 0.966 – 1.07 0.53 1613 17589 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1 0.939 – 1.07 0.974 1038 11601 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.02 0.953 – 1.09 0.583 928 10382 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 0.626 0.341 – 1.12 0.1 14 177 exclusion phecode
480.2 Viral pneumonia Respiratory 0.834 0.488 – 1.45 0.489 12 132 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.925 0.545 – 1.6 0.769 16 137 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.939 0.784 – 1.12 0.494 127 1192 exclusion phecode
481 Influenza Respiratory 0.951 0.738 – 1.22 0.692 64 638 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.973 0.683 – 1.4 0.875 31 422 exclusion phecode
495 Asthma Respiratory 1.01 0.978 – 1.04 0.608 4832 54529 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.01 0.738 – 1.39 0.932 44 530 exclusion phecode
496 Chronic airway obstruction Respiratory 1.04 0.988 – 1.09 0.141 1721 19932 exclusion phecode
496.1 Emphysema Respiratory 1.16 1.02 – 1.32 0.0233 245 2848 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.07 0.97 – 1.18 0.171 434 5493 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.08 0.971 – 1.19 0.159 399 5001 exclusion phecode
496.3 Bronchiectasis Respiratory 1.03 0.934 – 1.14 0.532 409 4630 exclusion phecode
497 Bronchitis Respiratory 0.791 0.64 – 0.976 0.0278 97 1263 exclusion phecode
500 Lung disease due to external agents Respiratory 1.11 0.797 – 1.58 0.526 36 356 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.97 0.568 – 1.64 0.906 16 168 exclusion phecode
500.2 Pneumoconiosis Respiratory 1.92 0.951 – 4.97 0.0929 8 58 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 0.993 0.794 – 1.24 0.95 91 881 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.19 0.998 – 1.42 0.051 139 1544 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 0.962 0.762 – 1.21 0.741 78 827 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.975 0.757 – 1.25 0.839 67 660 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.56 0.89 – 2.81 0.113 14 141 exclusion phecode
506 Empyema and pneumothorax Respiratory 0.916 0.778 – 1.08 0.288 157 1511 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.12 1.05 – 1.19 0.000911 960 10607 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.01 0.9 – 1.14 0.855 299 3573 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.02 0.921 – 1.14 0.652 367 4210 exclusion phecode
509.1 Respiratory failure Respiratory 0.974 0.863 – 1.1 0.666 293 3392 exclusion phecode
509.2 Respiratory insufficiency Respiratory 0.979 0.863 – 1.11 0.74 266 3054 exclusion phecode
509.5 Respiratory arrest Respiratory 1.53 0.984 – 2.4 0.0562 25 251 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.37 1.03 – 1.82 0.0284 52 605 exclusion phecode
510 Other diseases of lung Respiratory 1.1 0.911 – 1.32 0.329 121 1415 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.06 1.01 – 1.12 0.0203 1607 18103 exclusion phecode
512.1 Wheezing Respiratory 0.916 0.646 – 1.3 0.617 38 453 exclusion phecode
512.2 Painful respiration Respiratory 1.19 0.862 – 1.66 0.274 39 423 exclusion phecode
512.7 Shortness of breath Respiratory 1.07 1 – 1.14 0.0413 1003 11688 exclusion phecode
512.8 Cough Respiratory 1.09 0.996 – 1.19 0.0595 559 5885 exclusion phecode
512.9 Other dyspnea Respiratory 0.904 0.762 – 1.07 0.24 152 1615 exclusion phecode
513 Respiratory abnormalities Respiratory 1 0.787 – 1.28 0.973 67 967 exclusion phecode
513.3 Hypoventilation Respiratory 1.39 0.723 – 2.82 0.299 10 135 exclusion phecode
513.4 Hyperventilation Respiratory 0.987 0.737 – 1.33 0.93 46 654 exclusion phecode
513.8 Disorders of diaphragm Respiratory 0.954 0.879 – 1.11 0.899 4 80 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.07 0.964 – 1.18 0.204 403 4693 exclusion phecode
516 Abnormal sputum Respiratory 0.967 0.861 – 1.08 0.561 311 3467 exclusion phecode
516.1 Hemoptysis Respiratory 0.968 0.86 – 1.09 0.579 299 3378 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.01 0.957 – 1.06 0.746 1557 17356 exclusion phecode
519.2 Respiratory complications Respiratory 0.997 0.733 – 1.35 0.986 50 596 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1 0.949 – 1.06 0.963 1461 16254 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.13 0.862 – 1.47 0.378 54 609 exclusion phecode
520 Disorders of tooth development Digestive 1 0.887 – 1.13 0.994 288 2979 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.01 0.465 – 2.17 0.975 9 94 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.974 0.869 – 1.09 0.649 323 3372 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.02 0.929 – 1.13 0.643 449 5166 exclusion phecode
521.1 Dental caries Digestive 1.01 0.917 – 1.11 0.851 453 5161 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 0.995 0.891 – 1.11 0.927 340 3714 exclusion phecode
522.5 Periapical abscess Digestive 1 0.875 – 1.15 0.945 217 2470 exclusion phecode
523 Gingival and periodontal diseases Digestive 0.905 0.807 – 1.01 0.0873 317 3326 exclusion phecode
523.1 Gingivitis Digestive 1.23 0.827 – 1.86 0.305 28 233 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 0.889 0.773 – 1.02 0.0992 207 2230 exclusion phecode
523.31 Acute periodontitis Digestive 0.954 0.78 – 1.16 0.638 100 1184 exclusion phecode
523.32 Chronic periodontitis Digestive 0.865 0.714 – 1.05 0.131 115 1178 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.11 0.808 – 1.53 0.503 41 459 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.984 0.673 – 1.43 0.921 34 379 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.906 0.825 – 0.994 0.0366 481 5354 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.68 0.371 – 1.23 0.18 15 178 exclusion phecode
526 Diseases of the jaws Digestive 0.976 0.838 – 1.14 0.75 181 1927 exclusion phecode
526.1 Cysts of the jaws Digestive 0.985 0.733 – 1.32 0.918 50 523 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.55 0.727 – 3.55 0.229 9 106 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.07 0.82 – 1.39 0.62 60 636 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.04 0.802 – 1.36 0.743 60 641 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.896 0.533 – 1.48 0.658 15 206 exclusion phecode
526.9 Jaw disease NOS Digestive 0.847 0.64 – 1.12 0.235 57 523 exclusion phecode
527 Diseases of the salivary glands Digestive 1.11 0.923 – 1.32 0.272 132 1574 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.36 0.837 – 1.47 0.199 16 193 exclusion phecode
527.2 Sialoadenitis Digestive 1.07 0.849 – 1.35 0.564 79 873 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 0.961 0.493 – 1.96 0.903 10 141 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.34 0.889 – 2.01 0.147 23 283 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.06 0.988 – 1.15 0.101 753 7923 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.11 0.897 – 1.38 0.324 95 1013 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.05 0.827 – 1.32 0.7 81 874 exclusion phecode
528.12 Oral aphthae Digestive 1.61 0.934 – 2.87 0.0798 15 147 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.76 1.15 – 2.74 0.00814 25 308 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.935 0.601 – 1.46 0.756 22 234 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.821 0.486 – 1.39 0.44 17 173 exclusion phecode
528.5 Diseases of lips Digestive 1.04 0.867 – 1.24 0.697 133 1393 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.11 0.865 – 1.43 0.402 69 657 exclusion phecode
528.7 Sialolithiasis Digestive 1 0.76 – 1.32 0.985 58 507 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.03 0.902 – 1.17 0.683 247 2679 exclusion phecode
529.1 Glossitis Digestive 1.02 0.785 – 1.34 0.863 56 590 exclusion phecode
530 Diseases of esophagus Digestive 0.973 0.948 – 0.999 0.0428 6123 56943 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.973 0.947 – 1 0.046 5744 56038 exclusion phecode
530.11 GERD Digestive 0.96 0.931 – 0.99 0.0103 4324 49137 exclusion phecode
530.12 Ulcer of esophagus Digestive 0.905 0.838 – 0.978 0.0119 695 8038 exclusion phecode
530.14 Reflux esophagitis Digestive 0.962 0.917 – 1.01 0.112 1838 20721 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.938 0.826 – 1.06 0.319 261 3008 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1.05 0.921 – 1.19 0.482 257 2977 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.05 0.878 – 1.25 0.6 133 1451 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.836 0.534 – 1.29 0.412 24 273 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.799 0.606 – 1.05 0.106 57 475 exclusion phecode
530.9 Heartburn Digestive 1.01 0.921 – 1.11 0.853 492 5509 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.913 0.858 – 0.97 0.00333 1123 12567 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.889 0.703 – 1.12 0.315 74 788 exclusion phecode
531.2 Gastric ulcer Digestive 0.948 0.88 – 1.02 0.158 746 8245 exclusion phecode
531.3 Duodenal ulcer Digestive 0.888 0.801 – 0.984 0.0233 398 4355 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.11 0.829 – 1.49 0.471 52 721 exclusion phecode
532 Dysphagia Digestive 0.948 0.895 – 1 0.0666 1234 14225 exclusion phecode
535 Gastritis and duodenitis Digestive 1 0.972 – 1.03 0.977 5262 54923 exclusion phecode
535.1 Acute gastritis Digestive 0.923 0.805 – 1.06 0.252 221 2376 exclusion phecode
535.2 Atrophic gastritis Digestive 0.877 0.667 – 1.15 0.336 61 723 exclusion phecode
535.6 Duodenitis Digestive 0.979 0.92 – 1.04 0.51 1077 12640 exclusion phecode
535.8 Other specified gastritis Digestive 0.978 0.929 – 1.03 0.389 1611 18197 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.905 0.538 – 1.46 0.67 15 215 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.906 0.687 – 1.19 0.47 53 562 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1 0.926 – 1.09 0.91 631 6966 exclusion phecode
540 Appendiceal conditions Digestive 0.956 0.875 – 1.04 0.309 534 5340 exclusion phecode
540.1 Appendicitis Digestive 0.938 0.857 – 1.03 0.169 498 4968 exclusion phecode
540.11 Acute appendicitis Digestive 0.911 0.827 – 1 0.0594 447 4388 exclusion phecode
550 Abdominal hernia Digestive 0.977 0.952 – 1 0.0778 6384 57607 exclusion phecode
550.1 Inguinal hernia Digestive 1.03 0.934 – 1.15 0.513 411 4125 exclusion phecode
550.2 Diaphragmatic hernia Digestive 0.975 0.948 – 1 0.083 5328 53750 exclusion phecode
550.3 Femoral hernia Digestive 1.12 0.976 – 1.29 0.104 213 1809 exclusion phecode
550.4 Umbilical hernia Digestive 0.879 0.784 – 0.986 0.0279 325 3473 exclusion phecode
550.5 Ventral hernia Digestive 0.957 0.873 – 1.05 0.338 508 6297 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.01 0.942 – 1.09 0.719 786 8276 exclusion phecode
555.1 Regional enteritis Digestive 1.1 0.975 – 1.23 0.123 312 3455 exclusion phecode
555.2 Ulcerative colitis Digestive 0.979 0.897 – 1.07 0.64 555 5661 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 0.86 0.701 – 1.05 0.142 102 878 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.04 0.897 – 1.2 0.635 201 2257 exclusion phecode
556.1 Ulceration of intestine Digestive 1.11 0.926 – 1.34 0.249 126 1386 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.865 0.66 – 1.13 0.282 63 689 exclusion phecode
557.1 Celiac disease Digestive 0.82 0.742 – 0.906 8.84e-05 419 4466 exclusion phecode
558 Noninfectious gastroenteritis Digestive 0.983 0.947 – 1.02 0.35 3058 35914 exclusion phecode
559 Ileostomy status Digestive 1.01 0.887 – 1.14 0.935 273 2825 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.06 0.983 – 1.15 0.126 711 8502 exclusion phecode
560.1 Paralytic ileus Digestive 0.908 0.702 – 1.17 0.453 64 719 exclusion phecode
560.2 Impaction of intestine Digestive 1.04 0.774 – 1.4 0.792 51 651 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.14 0.963 – 1.34 0.127 145 1968 exclusion phecode
560.4 Other intestinal obstruction Digestive 1.08 0.996 – 1.17 0.0613 631 7573 exclusion phecode
561 Symptoms involving digestive system Digestive 1.01 0.979 – 1.05 0.452 3564 40538 exclusion phecode
561.1 Diarrhea Digestive 0.986 0.822 – 1.18 0.883 126 1196 exclusion phecode
561.2 Flatulence Digestive 0.954 0.854 – 1.07 0.405 351 4074 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 0.991 0.963 – 1.02 0.546 5187 46555 exclusion phecode
562.1 Diverticulosis Digestive 0.992 0.964 – 1.02 0.588 5179 46555 exclusion phecode
563 Constipation Digestive 1.03 0.982 – 1.08 0.238 1999 23784 exclusion phecode
564 Functional digestive disorders Digestive 1.01 0.982 – 1.05 0.396 3898 45036 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.02 0.959 – 1.08 0.596 1254 15443 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.15 1.03 – 1.29 0.0107 344 4072 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1 0.959 – 1.04 0.988 2408 29236 exclusion phecode
565 Anal and rectal conditions Digestive 1.01 0.966 – 1.05 0.686 2182 25167 exclusion phecode
565.1 Anal and rectal polyp Digestive 1 0.94 – 1.07 0.97 1073 12281 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.06 0.876 – 1.27 0.562 132 1555 exclusion phecode
568 Other disorders of peritoneum Digestive 1 0.919 – 1.09 0.969 554 7571 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.98 0.897 – 1.07 0.648 531 7238 exclusion phecode
569 Other disorders of intestine Digestive 1.08 1 – 1.16 0.0413 735 8839 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.797 0.52 – 1.2 0.269 24 305 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.12 0.844 – 1.49 0.413 52 852 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.03 0.929 – 1.13 0.61 420 5233 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1 0.878 – 1.14 0.985 243 3156 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.647 0.418 – 0.99 0.0422 17 188 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 0.993 0.781 – 1.26 0.955 73 837 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.07 0.878 – 1.3 0.503 103 1229 exclusion phecode
571.81 Portal hypertension Digestive 0.867 0.667 – 1.13 0.276 56 651 exclusion phecode
572 Ascites (non malignant) Digestive 1.02 0.9 – 1.14 0.805 297 3098 exclusion phecode
573 Other disorders of liver Digestive 0.936 0.828 – 1.06 0.282 278 3155 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.11 0.594 – 2.17 0.745 13 108 exclusion phecode
573.3 Hepatomegaly Digestive 0.942 0.668 – 1.33 0.727 31 403 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 0.852 0.72 – 1 0.0572 155 1441 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 0.944 0.87 – 1.02 0.162 623 6917 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.14 0.768 – 1.68 0.501 27 266 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 0.988 0.955 – 1.02 0.466 3663 41738 exclusion phecode
574.1 Cholelithiasis Digestive 0.996 0.961 – 1.03 0.834 3239 36901 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.04 0.927 – 1.17 0.506 314 3794 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.986 0.931 – 1.04 0.633 1284 14921 exclusion phecode
574.2 Calculus of bile duct Digestive 0.999 0.918 – 1.09 0.984 585 6618 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.935 0.86 – 1.02 0.118 605 6636 exclusion phecode
575 Other biliary tract disease Digestive 1.03 0.953 – 1.1 0.503 791 9272 exclusion phecode
575.1 Cholangitis Digestive 1.01 0.792 – 1.28 0.96 78 773 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.05 0.878 – 1.27 0.565 122 1312 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.929 0.756 – 1.14 0.476 95 1200 exclusion phecode
575.7 Other disorders of gallbladder Digestive 0.993 0.887 – 1.11 0.901 322 3746 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.11 0.976 – 1.27 0.11 251 2849 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.01 0.762 – 1.34 0.93 53 765 exclusion phecode
577 Diseases of pancreas Digestive 1.07 0.977 – 1.18 0.138 453 5342 exclusion phecode
577.1 Acute pancreatitis Digestive 1.12 1 – 1.25 0.0456 342 4034 exclusion phecode
577.2 Chronic pancreatitis Digestive 0.931 0.684 – 1.26 0.637 46 606 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.08 0.831 – 1.41 0.552 59 721 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1 0.971 – 1.04 0.806 3589 40052 exclusion phecode
578.1 Hematemesis Digestive 1.02 0.899 – 1.16 0.735 258 2908 exclusion phecode
578.2 Blood in stool Digestive 1.12 1 – 1.24 0.0402 366 4409 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 0.979 0.939 – 1.02 0.31 2419 27041 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.06 0.987 – 1.13 0.113 888 9722 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.04 0.929 – 1.17 0.488 328 3727 exclusion phecode
579.2 Splenomegaly Digestive 0.941 0.686 – 1.29 0.697 43 501 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.959 0.856 – 1.07 0.468 326 3724 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.915 0.799 – 1.05 0.193 231 2769 exclusion phecode
580.1 Glomerulonephritis Genitourinary 0.906 0.771 – 1.06 0.228 158 2081 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.08 0.589 – 2.16 0.794 10 130 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.775 0.506 – 1.16 0.211 20 242 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.922 0.771 – 1.1 0.365 133 1730 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.816 0.627 – 1.06 0.121 63 653 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.879 0.65 – 1.19 0.393 40 392 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.872 0.648 – 1.17 0.356 41 409 exclusion phecode
585 Renal failure Genitourinary 0.969 0.907 – 1.04 0.355 972 10578 exclusion phecode
585.1 Acute renal failure Genitourinary 0.98 0.902 – 1.06 0.639 632 6598 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.04 0.89 – 1.22 0.616 175 2009 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.967 0.869 – 1.08 0.546 367 4185 exclusion phecode
585.31 Renal dialysis Genitourinary 0.911 0.695 – 1.19 0.491 61 605 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 0.972 0.882 – 1.07 0.566 454 5436 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.17 0.803 – 1.7 0.403 27 351 exclusion phecode
586.11 Small kidney Genitourinary 1.05 0.691 – 1.59 0.797 23 309 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 0.947 0.803 – 1.12 0.519 157 2032 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.49 0.695 – 3.31 0.285 10 96 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.897 0.748 – 1.07 0.235 135 1511 exclusion phecode
587 Kidney replaced by transpant Genitourinary 0.856 0.63 – 1.16 0.309 47 487 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.17 0.738 – 1.83 0.493 23 215 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.1 0.688 – 1.74 0.689 20 211 exclusion phecode
590 Pyelonephritis Genitourinary 0.983 0.869 – 1.11 0.779 276 3232 exclusion phecode
591 Urinary tract infection Genitourinary 1.01 0.972 – 1.06 0.521 2323 27681 exclusion phecode
592 Cystitis and urethritis Genitourinary 0.95 0.874 – 1.03 0.22 616 7211 exclusion phecode
592.1 Cystitis Genitourinary 0.939 0.864 – 1.02 0.135 613 7157 exclusion phecode
592.11 Acute cystitis Genitourinary 0.692 0.473 – 1.01 0.0514 29 290 exclusion phecode
592.12 Chronic cystitis Genitourinary 0.897 0.774 – 1.04 0.146 193 2219 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.01 0.786 – 1.3 0.932 64 770 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.33 0.875 – 2.04 0.171 22 260 exclusion phecode
593 Hematuria Genitourinary 0.975 0.936 – 1.02 0.216 2558 27114 exclusion phecode
594 Urinary calculus Genitourinary 0.993 0.914 – 1.08 0.873 611 7224 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.05 0.938 – 1.17 0.403 342 3924 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.16 0.839 – 1.6 0.357 40 516 exclusion phecode
594.3 Calculus of ureter Genitourinary 1 0.868 – 1.16 0.959 196 2191 exclusion phecode
594.8 Renal colic Genitourinary 0.939 0.807 – 1.09 0.414 180 2181 exclusion phecode
595 Hydronephrosis Genitourinary 0.988 0.872 – 1.12 0.846 263 2913 exclusion phecode
596 Other disorders of bladder Genitourinary 0.958 0.899 – 1.02 0.182 1039 13582 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.75 1.04 – 3.05 0.0302 16 298 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1.09 0.959 – 1.24 0.186 248 3576 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.998 0.918 – 1.09 0.971 604 6860 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.02 0.919 – 1.12 0.763 440 5108 exclusion phecode
597.2 Urinary complications NEC Genitourinary 0.674 0.353 – 1.25 0.193 11 156 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.01 0.911 – 1.11 0.88 405 4739 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.06 0.783 – 1.43 0.693 48 577 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.988 0.953 – 1.02 0.504 3208 40739 exclusion phecode
599.1 Urinary obstruction Genitourinary 1.04 0.634 – 1.71 0.885 21 174 exclusion phecode
599.2 Retention of urine Genitourinary 1.05 0.96 – 1.16 0.271 488 6137 exclusion phecode
599.3 Dysuria Genitourinary 1.09 0.931 – 1.27 0.291 169 2043 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.983 0.941 – 1.03 0.434 2148 28699 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 0.996 0.914 – 1.09 0.925 562 6631 exclusion phecode
599.6 Oliguria and anuria Genitourinary 0.963 0.623 – 1.49 0.86 23 175 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 0.807 0.438 – 1.46 0.457 13 151 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1.15 0.984 – 1.34 0.0782 173 2281 exclusion phecode
610 Benign mammary dysplasias Genitourinary 1.03 0.956 – 1.12 0.405 712 8349 exclusion phecode
610.1 Cystic mastopathy Genitourinary 1.01 0.896 – 1.13 0.928 324 3492 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 0.974 0.786 – 1.21 0.808 95 1095 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 1.03 0.838 – 1.27 0.76 98 1097 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 1.03 0.925 – 1.15 0.573 356 4364 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.13 0.996 – 1.28 0.0576 261 2616 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.04 0.948 – 1.13 0.431 527 5591 exclusion phecode
611.1 Abnormal mammogram Genitourinary 1.36 0.942 – 2 0.0989 28 229 exclusion phecode
611.3 Lump or mass in breast Genitourinary 1.02 0.931 – 1.12 0.671 502 5338 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.1 0.949 – 1.27 0.206 198 2268 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.15 0.99 – 1.33 0.0656 191 2168 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 0.959 0.523 – 1.76 0.885 14 189 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 1.02 0.93 – 1.11 0.712 542 5652 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 0.999 0.871 – 1.14 0.986 232 2424 exclusion phecode
613.5 Mastodynia Genitourinary 1.55 0.971 – 2.53 0.061 20 228 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.843 0.735 – 0.966 0.0139 241 2511 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1.14 0.949 – 1.38 0.155 118 1101 exclusion phecode
613.9 Breast disorder NOS Genitourinary 0.96 0.759 – 1.21 0.727 78 811 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.01 0.957 – 1.07 0.696 1407 17653 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.03 0.937 – 1.12 0.588 505 7303 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.05 0.904 – 1.22 0.509 180 2307 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.848 0.759 – 0.91 0.503 9 194 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.11 0.898 – 1.36 0.336 100 1222 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.949 0.737 – 1.22 0.683 67 960 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.979 0.779 – 1.23 0.855 78 848 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.02 0.943 – 1.1 0.668 755 8763 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.01 0.909 – 1.13 0.827 365 4640 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.935 0.781 – 1.12 0.456 134 1555 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.04 0.909 – 1.18 0.585 234 2384 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.92 0.729 – 1.16 0.471 74 860 exclusion phecode
615 Endometriosis Genitourinary 1.04 0.961 – 1.12 0.356 711 11051 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.07 0.863 – 1.34 0.516 80 1055 exclusion phecode
618 Genital prolapse Genitourinary 1 0.968 – 1.03 0.999 3882 46658 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 1.01 0.969 – 1.06 0.605 2303 29678 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.992 0.948 – 1.04 0.741 2037 21638 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.07 0.874 – 1.32 0.494 99 2138 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.855 0.727 – 1 0.0551 158 2783 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1.03 0.989 – 1.07 0.162 2803 29683 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1 0.858 – 1.17 0.992 184 2289 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 1.07 1.01 – 1.14 0.0225 1253 12362 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.07 1 – 1.14 0.0466 932 9345 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.993 0.908 – 1.09 0.879 524 5961 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1 0.905 – 1.12 0.926 384 4375 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 0.971 0.653 – 1.43 0.879 28 248 exclusion phecode
621 Endometrial hyperplasia Genitourinary 1.02 0.922 – 1.14 0.648 374 4298 exclusion phecode
622 Polyp of female genital organs Genitourinary 1.04 1.01 – 1.07 0.018 4062 39495 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 1.05 1.01 – 1.09 0.0174 3007 29583 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 1.03 0.978 – 1.09 0.234 1401 13133 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.04 0.924 – 1.16 0.541 320 3941 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.9 0.8 – 1.01 0.0768 320 3359 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.81 0.646 – 1.01 0.0622 85 978 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 0.92 0.79 – 1.07 0.279 196 1897 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.988 0.94 – 1.04 0.644 1638 22082 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.04 0.967 – 1.12 0.282 719 8131 exclusion phecode
625.1 Dyspareunia Genitourinary 1.04 0.923 – 1.18 0.492 262 3225 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.05 1.01 – 1.08 0.011 3367 38946 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.04 1 – 1.08 0.0526 2995 36734 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.889 0.616 – 1.29 0.517 29 271 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1.04 0.995 – 1.1 0.0773 1736 28358 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.973 0.896 – 1.06 0.522 617 7000 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 1.04 0.974 – 1.11 0.235 949 11474 exclusion phecode
626.2 Dysmenorrhea Genitourinary 1.03 0.913 – 1.17 0.59 259 4528 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 1.59 0.844 – 3.02 0.115 13 390 exclusion phecode
626.8 Infertility, female Genitourinary 0.994 0.86 – 1.15 0.935 212 2161 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.04 1 – 1.07 0.0235 4738 44205 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 1.03 0.994 – 1.06 0.115 4295 38760 exclusion phecode
627.2 Symptomatic menopause Genitourinary 1.17 0.865 – 1.59 0.291 41 760 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.981 0.894 – 1.08 0.693 492 4822 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1.15 0.93 – 1.43 0.187 90 1220 exclusion phecode
628 Ovarian cyst Genitourinary 1 0.944 – 1.07 0.913 1109 14895 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.989 0.899 – 1.09 0.826 454 4082 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.1 0.9 – 1.35 0.338 98 883 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.19 0.838 – 1.68 0.321 37 348 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.19 0.975 – 1.49 0.0833 99 905 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.34 1 – 1.81 0.0466 47 430 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.06 0.825 – 1.36 0.651 68 589 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.955 0.792 – 1.15 0.61 129 1166 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 1.18 0.834 – 1.68 0.352 36 284 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.896 0.744 – 1.08 0.24 112 1080 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 1.74 0.428 – 16.1 0.409 1 30 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.05 0.8 – 1.37 0.738 60 545 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.33 0.816 – 2.19 0.244 19 154 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.87 0.45 – 1.57 0.641 10 91 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1 0.568 – 1.71 1 10 107 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.02 0.799 – 1.31 0.853 71 610 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.01 0.83 – 1.23 0.911 109 1050 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 2.05 0.845 – 6.09 0.123 7 60 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.988 0.569 – 1.72 0.964 14 109 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.19 0.438 – 3.38 0.678 4 58 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.722 0.35 – 1.39 0.32 9 111 exclusion phecode
650 Normal delivery Pregnancy Complications 1.03 0.825 – 1.28 0.81 90 967 exclusion phecode
651 Multiple gestation Pregnancy Complications 0.937 0.566 – 1.51 0.788 19 152 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.879 0.708 – 1.09 0.235 87 846 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.03 0.717 – 1.09 0.803 57 628 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.44 0.707 – 3.23 0.306 9 54 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.94 0.866 – 0.992 0.326 223 2069 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.675 0.188 – 1.8 0.413 4 54 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.855 0.696 – 1.05 0.129 100 984 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 1.11 1.02 – 1.19 0.486 36 322 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.967 0.908 – 1.02 0.539 255 2193 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.04 0.871 – 1.23 0.689 140 1354 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.982 0.943 – 1.12 0.936 12 88 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.09 1.01 – 1.14 0.692 13 114 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.8 0.734 – 7.81 0.271 5 33 exclusion phecode
679 Complications of in utero procedures Dermatologic 0.369 0.0564 – 1.05 0.106 4 25 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 0.99 0.93 – 1.05 0.758 1042 11411 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.849 0.681 – 1.06 0.139 87 915 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.2 0.983 – 1.47 0.0705 100 1154 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.977 0.906 – 1.05 0.543 735 7974 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.973 0.903 – 1.05 0.476 736 7971 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.977 0.906 – 1.05 0.543 733 7922 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.18 0.968 – 1.44 0.0972 110 1277 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 0.899 0.779 – 1.04 0.144 216 2345 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 0.998 0.889 – 1.12 0.979 314 3556 exclusion phecode
686.3 Pilonidal cyst Dermatologic 0.936 0.678 – 1.29 0.681 39 436 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 0.968 0.737 – 1.27 0.813 55 730 exclusion phecode
687 Symptoms affecting skin Dermatologic 0.882 0.7 – 1.11 0.275 84 1289 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.991 0.895 – 1.1 0.869 402 4188 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.04 0.775 – 1.4 0.782 50 637 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.868 0.463 – 1.6 0.627 13 253 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 0.966 0.879 – 1.06 0.472 461 5452 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.986 0.928 – 1.05 0.644 1147 11891 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.508 0.162 – 1.09 0.114 7 55 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.747 0.738 – 0.753 0.652 5 23 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.962 0.656 – 1.41 0.841 32 253 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 1.04 0.896 – 1.2 0.621 206 2299 exclusion phecode
694.1 Vitiligo Dermatologic 1.37 0.785 – 2.37 0.235 11 182 exclusion phecode
694.2 Other dyschromia Dermatologic 1.09 0.929 – 1.28 0.282 171 1867 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 0.826 0.547 – 1.24 0.34 20 206 exclusion phecode
695 Erythematous conditions Dermatologic 0.957 0.875 – 1.05 0.334 536 5650 exclusion phecode
695.1 Toxic erythema Dermatologic 0.687 0.408 – 1.12 0.128 19 228 exclusion phecode
695.2 Bullous dermatoses Dermatologic 0.931 0.619 – 1.38 0.719 26 256 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 1.22 0.648 – 2.4 0.524 10 96 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.724 0.401 – 1.26 0.246 15 158 exclusion phecode
695.3 Rosacea Dermatologic 0.831 0.626 – 1.1 0.189 52 546 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.06 0.874 – 1.27 0.571 113 1234 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.858 0.614 – 1.19 0.351 32 364 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.1 0.895 – 1.36 0.35 95 1035 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 0.952 0.819 – 1.11 0.523 192 2027 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 0.927 0.702 – 1.22 0.582 57 565 exclusion phecode
695.81 Erythema nodosum Dermatologic 1.02 0.607 – 1.69 0.948 20 185 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.08 0.868 – 1.35 0.476 88 935 exclusion phecode
696 Psoriasis and related disorders Dermatologic 1.03 0.925 – 1.16 0.554 344 3900 exclusion phecode
696.4 Psoriasis Dermatologic 1.02 0.914 – 1.14 0.692 339 3851 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 1.03 0.901 – 1.17 0.681 246 2821 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 1.08 0.891 – 1.3 0.438 119 1380 exclusion phecode
697 Sarcoidosis Dermatologic 0.931 0.767 – 1.13 0.467 122 1157 exclusion phecode
698 Pruritus and related conditions Dermatologic 0.934 0.791 – 1.1 0.418 150 1694 exclusion phecode
700 Corns and callosities Dermatologic 0.945 0.76 – 1.17 0.606 90 879 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.921 0.861 – 0.985 0.0164 919 10713 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 1.41 0.848 – 2.34 0.164 15 184 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.908 0.828 – 0.996 0.0411 487 5669 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.717 0.474 – 1.08 0.106 24 191 exclusion phecode
701.4 Keloid scar Dermatologic 1.12 0.83 – 1.52 0.435 42 476 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1.06 0.842 – 1.33 0.619 80 1022 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 0.887 0.505 – 1.54 0.65 12 200 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.02 0.957 – 1.08 0.606 1197 12401 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.968 0.885 – 1.06 0.477 545 6014 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 1.06 0.976 – 1.14 0.17 690 6727 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.07 0.845 – 1.35 0.581 72 771 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.978 0.816 – 1.17 0.805 126 1646 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.957 0.894 – 1.02 0.197 930 9617 exclusion phecode
704.1 Alopecia Dermatologic 1.08 0.776 – 1.51 0.63 39 349 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.742 0.377 – 1.43 0.349 12 134 exclusion phecode
705 Disorders of sweat glands Dermatologic 1.02 0.71 – 1.46 0.911 31 418 exclusion phecode
705.3 Hidradenitis Dermatologic 1.05 0.704 – 1.57 0.795 27 363 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.17 0.905 – 1.51 0.227 67 768 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1.01 0.957 – 1.07 0.718 1497 15963 exclusion phecode
706.1 Acne Dermatologic 0.997 0.602 – 1.65 0.99 15 150 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1 0.954 – 1.06 0.863 1586 16881 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.07 0.952 – 1.21 0.246 282 2844 exclusion phecode
707.1 Decubitus ulcer Dermatologic 0.993 0.841 – 1.17 0.938 151 1423 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 1.02 0.952 – 1.1 0.547 829 9111 exclusion phecode
709.2 Sicca syndrome Dermatologic 0.968 0.829 – 1.13 0.676 171 1839 exclusion phecode
709.3 Systemic sclerosis Dermatologic 0.976 0.757 – 1.25 0.845 65 561 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.05 0.631 – 1.79 0.828 20 173 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.04 0.959 – 1.13 0.331 596 6692 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.997 0.798 – 1.24 0.978 78 841 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.03 0.817 – 1.29 0.818 73 777 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.02 0.66 – 1.55 0.936 20 276 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.02 0.783 – 1.31 0.905 60 543 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 1.06 0.821 – 1.36 0.653 56 662 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.05 0.793 – 1.39 0.722 49 484 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 0.918 0.452 – 1.86 0.796 10 142 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.01 0.668 – 1.52 0.964 24 205 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 0.424 0.123 – 0.966 0.0661 7 48 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.06 0.997 – 1.12 0.0627 1171 13565 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.06 0.998 – 1.13 0.059 1082 12311 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1 0.889 – 1.13 0.947 282 3548 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.17 0.804 – 1.7 0.403 26 314 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.979 0.754 – 1.27 0.871 61 760 exclusion phecode
716 Other arthropathies Musculoskeletal 0.997 0.962 – 1.03 0.815 7511 56916 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.06 0.98 – 1.14 0.154 760 9731 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 1 0.966 – 1.04 0.811 2747 32575 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 0.989 0.964 – 1.01 0.366 7143 56584 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.15 1.03 – 1.3 0.0164 294 3164 exclusion phecode
720 Spinal stenosis Musculoskeletal 1.06 0.985 – 1.15 0.114 675 8033 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1 0.952 – 1.06 0.933 1536 19218 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.01 0.948 – 1.08 0.72 958 12530 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.936 0.639 – 1.37 0.723 25 353 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 1.13 0.886 – 1.44 0.32 64 779 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.02 0.964 – 1.07 0.532 1427 17680 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.929 0.701 – 1.21 0.53 69 870 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.1 1.01 – 1.2 0.0381 491 6485 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1 0.914 – 3.05 0.996 4 106 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.964 0.891 – 1.04 0.352 671 8077 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 0.968 0.75 – 1.25 0.802 61 814 exclusion phecode
723.1 Torticollis Musculoskeletal 0.963 0.625 – 1.46 0.856 20 212 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 0.99 0.885 – 1.11 0.865 336 3965 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1.05 0.851 – 1.28 0.666 96 1118 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 1.06 0.863 – 1.3 0.57 95 1116 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 0.922 0.868 – 0.996 0.708 12 164 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 0.966 0.845 – 1.11 0.616 236 2779 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.976 0.937 – 1.02 0.246 2510 30838 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.957 0.912 – 1 0.0766 1775 21536 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.98 0.771 – 1.25 0.867 67 804 exclusion phecode
726.3 Bursitis Musculoskeletal 1.33 1 – 1.75 0.0424 52 681 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.03 0.973 – 1.08 0.331 1445 16754 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.09 0.997 – 1.19 0.0589 502 6165 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.811 0.379 – 1.64 0.551 10 111 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.02 0.947 – 1.1 0.579 703 7798 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.954 0.789 – 1.15 0.621 115 1377 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.12 0.853 – 1.47 0.418 60 682 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.14 0.697 – 1.88 0.599 22 276 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.947 0.852 – 1.05 0.316 380 3834 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.21 0.919 – 1.59 0.165 55 688 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.964 0.872 – 1.07 0.483 414 4244 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.973 0.873 – 1.09 0.627 355 3521 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.01 0.951 – 1.07 0.725 1093 13777 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.974 0.854 – 1.11 0.695 241 3348 exclusion phecode
729.3 Panniculitis Musculoskeletal 1.17 0.7 – 1.94 0.53 18 189 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.07 0.823 – 1.39 0.602 58 776 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.02 0.777 – 1.34 0.87 55 737 exclusion phecode
732 Osteochondropathies Musculoskeletal 1.14 0.899 – 1.45 0.271 72 816 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.954 0.681 – 1.33 0.775 36 397 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.17 1.07 – 1.3 0.663 5 57 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.979 0.891 – 1.07 0.651 484 4939 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.32 1.06 – 1.64 0.0121 90 834 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.04 0.862 – 1.26 0.678 107 1138 exclusion phecode
733.6 Costochondritis Musculoskeletal 1.04 0.727 – 1.48 0.825 33 352 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.1 0.955 – 1.27 0.18 210 2508 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.14 0.691 – 1.89 0.595 18 208 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1.02 0.986 – 1.06 0.228 2959 33036 exclusion phecode
735.1 Flat foot Musculoskeletal 1.18 0.888 – 1.56 0.247 51 525 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 0.994 0.943 – 1.05 0.835 1512 16965 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.06 0.977 – 1.16 0.157 593 6878 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.95 0.859 – 1.05 0.324 418 4794 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.02 0.976 – 1.06 0.396 2187 24370 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1 0.895 – 1.12 0.967 317 3381 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.2 0.882 – 1.64 0.237 44 475 exclusion phecode
737 Curvature of spine Musculoskeletal 1.2 1.06 – 1.36 0.00351 290 3359 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.19 1.05 – 1.35 0.00505 280 3220 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.14 1.03 – 1.26 0.0111 400 4716 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.15 1.03 – 1.28 0.012 345 4108 exclusion phecode
739 Contracture of joint Musculoskeletal 0.971 0.772 – 1.22 0.797 88 1005 exclusion phecode
740 Osteoarthrosis Musculoskeletal 0.988 0.959 – 1.02 0.387 5919 53119 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.978 0.946 – 1.01 0.199 3782 39791 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.973 0.928 – 1.02 0.262 1820 20641 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.944 0.738 – 1.21 0.642 69 752 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.934 0.782 – 1.12 0.448 126 1637 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.992 0.953 – 1.03 0.691 2544 31216 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.995 0.913 – 1.09 0.917 563 6754 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.452 0.226 – 0.845 0.0124 13 184 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 0.93 0.766 – 1.13 0.46 110 1339 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.847 0.56 – 1.27 0.413 32 307 exclusion phecode
741.4 Joint effusions Musculoskeletal 1.07 0.924 – 1.23 0.382 213 2333 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 2.1 1.21 – 3.75 0.00747 14 190 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 1 0.927 – 2.24 0.988 9 113 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.916 0.826 – 1.01 0.0922 407 4700 exclusion phecode
742.1 Loose body in joint Musculoskeletal 0.874 0.614 – 1.23 0.435 38 473 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.975 0.43 – 2.27 0.945 7 133 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 0.882 0.707 – 1.1 0.259 86 929 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.904 0.797 – 1.02 0.11 273 3124 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.97 0.929 – 1.01 0.159 2272 24171 exclusion phecode
743.1 Osteoporosis Musculoskeletal 0.967 0.924 – 1.01 0.146 2037 21524 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 0.971 0.926 – 1.02 0.217 1868 19827 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 0.832 0.677 – 1.02 0.0773 95 944 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.04 0.858 – 1.27 0.66 113 1177 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.01 0.861 – 1.18 0.922 175 1916 exclusion phecode
745 Pain in joint Musculoskeletal 1.02 0.967 – 1.08 0.463 1411 17187 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.03 0.93 – 1.13 0.616 445 4583 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.05 0.945 – 1.16 0.385 413 4265 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1.16 0.944 – 1.42 0.157 107 1070 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.853 0.591 – 1.23 0.38 30 319 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.998 0.88 – 1.13 0.972 265 2761 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.824 0.583 – 1.17 0.26 31 334 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.07 0.4 – 3.1 0.88 5 84 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.09 0.805 – 1.48 0.572 59 490 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.762 0.628 – 0.922 0.00491 110 1258 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.873 0.616 – 1.23 0.428 37 480 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.812 0.767 – 0.901 0.307 19 257 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.716 0.561 – 0.911 0.00625 72 766 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.913 0.664 – 1.25 0.565 41 436 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.437 0.285 – 0.649 6.1e-05 30 294 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.88 0.766 – 1.01 0.069 225 2614 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.987 0.811 – 1.2 0.897 112 1220 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.996 0.82 – 1.21 0.964 114 1231 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.744 0.607 – 0.91 0.00392 113 1407 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.704 0.522 – 0.943 0.0175 54 704 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.755 0.564 – 1.01 0.0535 51 598 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.05 0.815 – 1.36 0.689 61 666 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.08 0.811 – 1.44 0.586 51 538 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.979 0.712 – 1.34 0.891 41 428 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.859 0.46 – 1.6 0.616 10 116 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.37 0.942 – 2.02 0.0954 31 255 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.18 0.713 – 1.98 0.519 20 163 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.1 0.723 – 1.68 0.642 25 251 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.858 0.692 – 1.06 0.159 91 1019 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.971 0.714 – 1.31 0.845 47 498 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.717 0.494 – 1.03 0.0686 31 383 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.56 0.354 – 0.862 0.00863 22 254 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.939 0.77 – 1.14 0.529 106 1190 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.06 0.627 – 1.77 0.832 17 152 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.893 0.697 – 1.14 0.362 72 894 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.745 0.452 – 1.2 0.203 17 320 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.903 0.45 – 1.74 0.737 9 175 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.823 0.566 – 1.19 0.288 33 485 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.744 0.451 – 1.21 0.214 15 226 exclusion phecode
760 Back pain Symptoms 0.983 0.938 – 1.03 0.485 1861 23664 exclusion phecode
761 Cervicalgia Symptoms 1.07 0.952 – 1.21 0.248 284 3820 exclusion phecode
764 Sciatica Symptoms 1.06 0.959 – 1.16 0.26 446 5434 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.901 0.784 – 1.03 0.136 222 2565 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 0.949 0.785 – 1.15 0.582 116 1209 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.09 0.928 – 1.29 0.284 155 1803 exclusion phecode
771.1 Swelling of limb Symptoms 1.01 0.939 – 1.09 0.795 781 9754 exclusion phecode
772 Symptoms of the muscles Symptoms 0.986 0.81 – 1.2 0.886 112 1269 exclusion phecode
773 Pain in limb Symptoms 0.967 0.909 – 1.03 0.276 1105 13931 exclusion phecode
780 Hypothermia/Chills Symptoms 0.67 0.408 – 1.08 0.0944 21 285 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.03 0.918 – 1.17 0.578 277 3591 exclusion phecode
782.3 Edema Symptoms 1.06 0.931 – 1.21 0.37 252 3038 exclusion phecode
782.6 Pallor and flushing Symptoms 1.17 0.772 – 1.78 0.433 26 319 exclusion phecode
783 Fever of unknown origin Symptoms 1 0.928 – 1.09 0.907 670 7181 exclusion phecode
785 Abdominal pain Symptoms 0.976 0.954 – 0.999 0.0443 8094 58491 exclusion phecode
788 Syncope and collapse Symptoms 0.963 0.911 – 1.02 0.184 1374 15465 exclusion phecode
789 Nausea and vomiting Symptoms 0.997 0.956 – 1.04 0.888 2385 27018 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.06 0.649 – 1.74 0.8 20 259 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.06 0.648 – 1.72 0.813 22 198 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 0.946 0.864 – 1.04 0.23 513 5675 exclusion phecode
791 Gangrene Symptoms 0.922 0.713 – 1.19 0.527 70 704 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.971 0.707 – 1.33 0.852 39 409 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.992 0.643 – 1.52 0.971 24 281 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.07 0.872 – 1.32 0.497 101 1060 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.731 0.379 – 1.34 0.311 12 98 exclusion phecode
797 Shock Symptoms 0.95 0.529 – 1.65 0.85 16 164 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.46 0.703 – 3.03 0.273 8 88 exclusion phecode
798 Malaise and fatigue Symptoms 0.935 0.861 – 1.01 0.106 619 7171 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 0.94 0.783 – 1.13 0.505 125 1518 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 0.958 0.911 – 1.01 0.0982 1659 16384 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.904 0.824 – 0.991 0.0319 479 4694 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.04 0.708 – 1.51 0.851 29 298 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.05 0.953 – 1.16 0.314 422 3979 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.943 0.794 – 1.12 0.501 142 1308 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1 0.912 – 1.11 0.933 446 4681 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 0.973 0.876 – 1.08 0.609 373 3985 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 0.966 0.813 – 1.15 0.69 141 1417 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.944 0.903 – 0.986 0.00989 2204 20980 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 0.958 0.863 – 1.06 0.413 398 4148 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.943 0.896 – 0.992 0.0236 1651 15323 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.903 0.772 – 1.05 0.197 164 1605 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.922 0.844 – 1.01 0.0665 571 5687 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.759 0.652 – 0.882 0.00031 195 2144 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.03 0.824 – 1.28 0.793 86 952 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.868 0.747 – 1.01 0.0619 195 2044 exclusion phecode
817 Concussion Injuries & Poisonings 0.82 0.54 – 1.24 0.33 25 334 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.941 0.736 – 1.2 0.621 69 750 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.03 0.926 – 1.15 0.563 343 3285 exclusion phecode
823 Torus fracture Injuries & Poisonings 1.08 0.965 – 1.21 0.181 333 3147 exclusion phecode
830 Dislocation Injuries & Poisonings 0.951 0.839 – 1.08 0.427 277 2900 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 1 0.957 – 1.05 0.972 2121 24744 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.933 0.729 – 1.19 0.571 74 881 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.775 0.597 – 1 0.0518 65 676 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.06 0.989 – 1.14 0.101 856 10460 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1 0.704 – 1.42 0.985 32 316 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.1 0.856 – 1.4 0.462 74 914 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.983 0.846 – 1.14 0.818 190 2164 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.13 0.962 – 1.33 0.131 165 1989 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.02 0.937 – 1.1 0.704 630 7480 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.06 0.981 – 1.15 0.137 635 7277 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 0.898 0.424 – 1.87 0.761 10 103 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.04 0.944 – 1.15 0.406 430 4808 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.15 0.847 – 1.55 0.37 40 389 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 0.948 0.61 – 1.45 0.799 20 227 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.04 0.93 – 1.16 0.494 346 3996 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.06 0.702 – 1.61 0.76 23 294 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.687 0.263 – 1.41 0.294 4 61 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 0.996 0.903 – 1.1 0.934 448 4677 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.4 0.574 – 3.78 0.451 5 41 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.567 0.254 – 1.19 0.128 10 93 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.936 0.594 – 1.45 0.759 22 290 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 0.97 0.636 – 1.48 0.884 24 322 exclusion phecode
873 Broken tooth Injuries & Poisonings 1.08 0.795 – 1.47 0.612 44 469 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 0.891 0.431 – 1.81 0.732 11 139 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 0.794 0.713 – 1.39 0.332 17 207 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.09 0.932 – 1.28 0.274 175 1904 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 0.971 0.895 – 1.05 0.467 633 7100 exclusion phecode
916 Contusion Injuries & Poisonings 1.01 0.882 – 1.16 0.889 230 2512 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 1.11 0.801 – 1.52 0.524 41 382 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.19 0.931 – 1.51 0.164 71 791 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 1.12 0.822 – 1.52 0.47 46 454 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1 0.898 – 1.11 0.995 361 4149 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.991 0.737 – 1.33 0.951 49 521 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.35 0.854 – 2.16 0.187 20 202 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.919 0.74 – 1.14 0.44 86 1069 exclusion phecode
947 Urticaria Injuries & Poisonings 1.01 0.794 – 1.28 0.946 76 829 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.07 0.833 – 1.37 0.6 76 853 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.04 0.793 – 1.36 0.768 55 662 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.13 0.85 – 1.5 0.402 53 607 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.999 0.757 – 1.32 0.996 54 635 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 0.963 0.488 – 1.97 0.912 10 88 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.99 0.382 – 2.47 0.983 5 54 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.01 0.982 – 1.05 0.378 3891 45305 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.01 0.973 – 1.04 0.661 3334 38611 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.01 0.816 – 1.25 0.931 93 1190 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.93 0.813 – 1.06 0.282 237 2939 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.16 0.944 – 1.43 0.154 100 1005 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.2 0.973 – 1.49 0.0855 96 998 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.08 0.784 – 1.49 0.624 42 420 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.19 0.867 – 1.64 0.269 39 458 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.21 0.88 – 1.67 0.229 39 460 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.07 1 – 1.13 0.0359 1175 14434 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.01 0.881 – 1.15 0.902 232 3343 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.796 0.611 – 1.04 0.0864 61 771 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.982 0.729 – 1.32 0.904 48 608 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.1 0.867 – 1.4 0.423 72 871 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.904 0.741 – 1.1 0.317 110 1475 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 0.964 0.853 – 1.09 0.561 270 3400 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.14 0.754 – 1.74 0.53 25 268 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.12 0.78 – 1.6 0.534 33 377 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.77 0.98 – 3.41 0.0571 10 113 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 0.724 0.424 – 1.22 0.205 14 171 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.816 0.466 – 1.41 0.45 14 118 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.23 0.718 – 2.22 0.459 15 120 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.2 1.08 – 1.28 0.44 13 129 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.953 0.694 – 1.3 0.758 43 548 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 0.958 0.786 – 1.17 0.665 110 1358 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.747 0.503 – 1.11 0.132 23 283 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 0.642 0.186 – 1.75 0.35 4 73 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 2.2 1.15 – 4.65 0.0201 10 98 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 1.32 0.899 – 1.93 0.15 30 235 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.925 0.531 – 1.58 0.772 12 122 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.03 0.947 – 1.12 0.512 634 6384 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.01 0.927 – 1.11 0.783 552 5667 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.01 0.927 – 1.11 0.783 552 5667 exclusion phecode
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