Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Drinks per week UK Biobank (UKB) PheWAS analysis

Drinks per week — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID exprsweb-alcohol-amount-drinksperweek-lassosum-ukb-20211120Legacy LASSOSUMlassosumLarge GWAS

Evaluation cohort: UK Biobank (UKB).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: study-defined normal-range subset.

For this ExPRS, the exclusion sensitivity scan keeps only the study-defined normal-range subset for Drinks per week before rerunning the PheWAS. The preserved release does not include numeric bounds for this trait. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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Signal overview

The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.

276 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1 0.98 – 1.02 0.901 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.04 1 – 1.08 0.0454 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.08 0.999 – 1.17 0.0519 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 0.95 0.885 – 1.02 0.15 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 0.847 0.646 – 1.11 0.229 55 550 all phecode
010 Tuberculosis Infectious Diseases 0.98 0.835 – 1.15 0.806 166 1659 all phecode
038 Septicemia Infectious Diseases 1.01 0.979 – 1.04 0.494 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.03 0.957 – 1.1 0.448 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 0.95 0.866 – 1.04 0.27 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 1.02 0.999 – 1.04 0.0704 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.03 0.99 – 1.07 0.147 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 1.06 1.01 – 1.12 0.0203 1641 16433 all phecode
041.4 E. coli Infectious Diseases 1.03 0.99 – 1.07 0.147 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 0.957 0.865 – 1.06 0.399 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.04 0.842 – 1.28 0.726 95 949 all phecode
054 Herpes simplex Infectious Diseases 1.09 0.948 – 1.26 0.224 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 1.2 1.11 – 1.31 1.93e-05 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 1.16 0.904 – 1.48 0.249 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.21 1.01 – 1.46 0.0378 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.32 1.16 – 1.5 2.79e-05 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.04 0.917 – 1.17 0.565 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 1 0.911 – 1.11 0.932 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.863 0.73 – 1.02 0.0852 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.785 0.651 – 0.948 0.0117 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 1.04 0.977 – 1.11 0.208 1004 10036 all phecode
079 Viral infection Infectious Diseases 0.999 0.96 – 1.04 0.951 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 1.34 1.05 – 1.71 0.0188 64 640 all phecode
080 Postoperative infection Infectious Diseases 1.02 0.989 – 1.05 0.206 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.04 0.998 – 1.08 0.0647 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.838 0.653 – 1.08 0.164 71 709 all phecode
1000 Burns Injuries & Poisonings 1.11 1.01 – 1.21 0.0224 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 1.01 0.953 – 1.07 0.711 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1 0.975 – 1.03 0.881 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.21 1.07 – 1.36 0.00193 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 0.969 0.918 – 1.02 0.246 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 1.15 1.02 – 1.31 0.027 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 1.3 1.14 – 1.48 0.000111 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.12 1.05 – 1.19 0.000598 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 1.05 1.03 – 1.07 1.45e-05 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 1 0.974 – 1.03 0.998 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.03 1.01 – 1.05 0.0067 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 0.996 0.815 – 1.22 0.968 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 0.984 0.877 – 1.1 0.784 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.15 0.918 – 1.44 0.227 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 1.06 1.03 – 1.09 0.000263 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.02 0.999 – 1.03 0.0609 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.12 0.994 – 1.27 0.0623 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 1.13 0.994 – 1.27 0.0628 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.06 0.85 – 1.33 0.596 74 756 all phecode
110.12 Althete's foot Infectious Diseases 1.14 0.958 – 1.36 0.14 141 1410 all phecode
112 Candidiasis Infectious Diseases 1.06 1.01 – 1.11 0.0102 2126 21275 all phecode
117 Mycoses Infectious Diseases 0.975 0.861 – 1.11 0.695 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 0.967 0.822 – 1.14 0.683 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 1.02 0.807 – 1.29 0.857 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 1.03 0.817 – 1.31 0.79 69 689 all phecode
134 Helminthiases Infectious Diseases 0.898 0.749 – 1.08 0.249 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 0.957 0.785 – 1.17 0.662 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.985 0.851 – 1.14 0.845 205 2050 all phecode
145 Cancer of mouth Neoplasms 1.06 0.976 – 1.15 0.172 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 1.09 0.972 – 1.23 0.136 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 0.909 0.745 – 1.11 0.345 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.33 1.01 – 1.76 0.0412 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.17 1.08 – 1.27 0.000152 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 1.06 0.928 – 1.2 0.41 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 1.3 1.15 – 1.47 3.99e-05 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.961 0.737 – 1.25 0.768 57 570 all phecode
150 Cancer of esophagus Neoplasms 1.02 0.947 – 1.1 0.6 762 7630 all phecode
151 Cancer of stomach Neoplasms 0.99 0.908 – 1.08 0.817 569 5696 all phecode
153 Colorectal cancer Neoplasms 1.01 0.984 – 1.05 0.357 4580 45799 all phecode
153.2 Colon cancer Neoplasms 1.01 0.978 – 1.05 0.432 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.02 0.976 – 1.07 0.367 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.09 0.981 – 1.2 0.112 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.19 1.01 – 1.39 0.0338 158 1580 all phecode
157 Pancreatic cancer Neoplasms 1.12 1.03 – 1.21 0.00552 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.03 0.965 – 1.09 0.404 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.02 0.997 – 1.05 0.0853 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.953 0.823 – 1.1 0.525 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.06 0.92 – 1.22 0.423 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.935 0.806 – 1.08 0.374 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 1.13 0.866 – 1.46 0.376 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 1.12 1.08 – 1.17 3.42e-09 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.13 1.08 – 1.18 9.95e-08 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.952 0.862 – 1.05 0.323 437 4364 all phecode
170.1 Bone cancer Neoplasms 0.951 0.797 – 1.14 0.58 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 0.947 0.846 – 1.06 0.344 331 3303 all phecode
172 Skin cancer Neoplasms 0.982 0.964 – 0.999 0.0413 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.974 0.936 – 1.01 0.201 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 0.975 0.937 – 1.01 0.207 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.987 0.967 – 1.01 0.182 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 0.951 0.878 – 1.03 0.213 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.998 0.855 – 1.16 0.978 181 1818 all phecode
174 Breast cancer Neoplasms 1.03 1.01 – 1.05 0.00586 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 1.03 1.01 – 1.05 0.00603 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.03 1.01 – 1.05 0.00506 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.12 0.918 – 1.36 0.27 115 1148 all phecode
175 Acquired absence of breast Neoplasms 1.05 1.01 – 1.1 0.0246 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 1.03 0.988 – 1.08 0.159 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 1.02 0.896 – 1.15 0.798 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.04 0.996 – 1.09 0.0741 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 0.939 0.886 – 0.995 0.0336 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 0.978 0.925 – 1.03 0.441 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.946 0.885 – 1.01 0.109 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.952 0.889 – 1.02 0.158 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.05 0.934 – 1.18 0.408 305 3049 all phecode
185 Cancer of prostate Neoplasms 0.979 0.954 – 1.01 0.12 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 1 0.908 – 1.1 0.995 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.937 0.734 – 1.2 0.6 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.95 0.844 – 1.07 0.401 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.02 0.836 – 1.24 0.873 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.988 0.957 – 1.02 0.471 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.955 0.897 – 1.02 0.148 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.949 0.891 – 1.01 0.109 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.14 0.885 – 1.48 0.303 66 660 all phecode
189.2 Cancer of bladder Neoplasms 1.01 0.973 – 1.06 0.49 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.02 0.974 – 1.06 0.43 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.978 0.826 – 1.16 0.799 144 1439 all phecode
190 Cancer of eye Neoplasms 0.902 0.772 – 1.05 0.192 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.937 0.866 – 1.01 0.109 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 0.934 0.857 – 1.02 0.125 566 5650 all phecode
191.11 Cancer of brain Neoplasms 0.948 0.866 – 1.04 0.246 525 5240 all phecode
193 Thyroid cancer Neoplasms 1 0.896 – 1.12 0.963 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 1.11 0.896 – 1.36 0.35 95 949 all phecode
195 Cancer, suspected or other Neoplasms 1.02 1.01 – 1.04 0.00644 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.02 1 – 1.04 0.0111 16267 159497 all phecode
197 Chemotherapy Neoplasms 1.01 0.994 – 1.02 0.289 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 1.03 1.01 – 1.05 0.00605 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.03 1 – 1.06 0.0276 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.06 1.02 – 1.11 0.00713 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.01 0.958 – 1.06 0.716 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.04 0.995 – 1.08 0.0847 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.05 0.982 – 1.13 0.143 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.02 0.976 – 1.07 0.384 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.978 0.84 – 1.14 0.776 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 0.989 0.937 – 1.04 0.703 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 0.886 0.721 – 1.09 0.249 95 950 all phecode
200 Myeloproliferative disease Neoplasms 1.03 0.961 – 1.1 0.438 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 1.15 1.04 – 1.28 0.00725 387 3867 all phecode
201 Hodgkin's disease Neoplasms 0.953 0.837 – 1.08 0.464 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.01 0.968 – 1.06 0.626 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.02 0.968 – 1.07 0.506 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 1.02 0.912 – 1.13 0.764 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 1.03 0.944 – 1.12 0.523 581 5824 all phecode
204 Leukemia Neoplasms 0.975 0.927 – 1.03 0.333 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 1.02 0.935 – 1.11 0.669 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.18 0.904 – 1.53 0.226 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.988 0.902 – 1.08 0.803 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 0.951 0.863 – 1.05 0.309 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.949 0.845 – 1.07 0.382 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.957 0.808 – 1.13 0.613 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 0.93 0.852 – 1.01 0.102 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 1.06 1.04 – 1.07 6.66e-14 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.03 0.967 – 1.1 0.341 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.926 0.9 – 0.953 1.48e-07 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.02 0.914 – 1.14 0.721 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.965 0.86 – 1.08 0.549 318 3187 all phecode
214 Lipoma Neoplasms 1 0.975 – 1.03 0.974 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.02 0.987 – 1.05 0.271 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.996 0.936 – 1.06 0.901 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 1 0.977 – 1.02 0.999 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.06 0.979 – 1.16 0.148 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.05 0.96 – 1.14 0.304 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 0.996 0.975 – 1.02 0.679 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 0.992 0.972 – 1.01 0.466 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.973 0.872 – 1.08 0.617 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 0.964 0.912 – 1.02 0.185 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.978 0.849 – 1.13 0.763 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.963 0.815 – 1.14 0.653 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.904 0.774 – 1.06 0.2 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 1.02 0.85 – 1.23 0.822 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.04 0.806 – 1.34 0.773 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.913 0.849 – 0.981 0.0131 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.911 0.846 – 0.981 0.0141 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.956 0.737 – 1.24 0.735 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.926 0.818 – 1.05 0.223 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.966 0.901 – 1.04 0.336 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.15 0.987 – 1.34 0.0728 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.999 0.898 – 1.11 0.986 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.848 0.754 – 0.953 0.00576 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.02 0.966 – 1.07 0.505 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.01 0.965 – 1.05 0.749 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.931 0.857 – 1.01 0.0968 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.914 0.859 – 0.973 0.00485 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.9 0.819 – 0.99 0.0295 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.93 0.859 – 1.01 0.0741 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.979 0.933 – 1.03 0.394 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 0.989 0.898 – 1.09 0.825 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.09 0.879 – 1.34 0.445 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.01 0.847 – 1.2 0.927 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 0.975 0.959 – 0.992 0.00425 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.963 0.904 – 1.03 0.241 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.913 0.74 – 1.13 0.393 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.975 0.958 – 0.992 0.00442 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 0.998 0.883 – 1.13 0.975 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.01 0.875 – 1.16 0.913 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.987 0.855 – 1.14 0.858 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 0.967 0.87 – 1.08 0.539 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 0.956 0.942 – 0.97 2.16e-09 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.953 0.917 – 0.991 0.0164 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.11 0.97 – 1.27 0.127 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.3 1.03 – 1.65 0.0279 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.972 0.884 – 1.07 0.565 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.04 0.88 – 1.22 0.666 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.955 0.94 – 0.97 4.84e-09 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.96 0.79 – 1.17 0.681 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.953 0.825 – 1.1 0.517 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.944 0.884 – 1.01 0.0846 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1 0.916 – 1.1 0.936 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 0.954 0.881 – 1.03 0.238 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.01 0.894 – 1.15 0.827 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.923 0.834 – 1.02 0.121 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.02 0.849 – 1.21 0.869 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.983 0.88 – 1.1 0.77 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.941 0.889 – 0.995 0.0338 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.01 0.942 – 1.08 0.831 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.975 0.909 – 1.05 0.476 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.981 0.911 – 1.06 0.607 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.981 0.829 – 1.16 0.821 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.956 0.884 – 1.03 0.264 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.895 0.772 – 1.04 0.144 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.858 0.692 – 1.06 0.16 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.978 0.862 – 1.11 0.729 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.915 0.74 – 1.13 0.411 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.03 0.872 – 1.21 0.748 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.96 0.885 – 1.04 0.334 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.918 0.787 – 1.07 0.275 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.863 0.709 – 1.05 0.143 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.981 0.769 – 1.25 0.878 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.988 0.887 – 1.1 0.833 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.99 0.888 – 1.1 0.86 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 0.9 0.788 – 1.03 0.122 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.934 0.81 – 1.08 0.345 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 1.06 0.902 – 1.24 0.49 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.09 0.929 – 1.29 0.279 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.941 0.766 – 1.16 0.562 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.02 0.863 – 1.2 0.832 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.01 0.878 – 1.17 0.87 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 0.965 0.736 – 1.26 0.794 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 0.989 0.92 – 1.06 0.755 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.02 0.963 – 1.08 0.473 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.1 1.02 – 1.19 0.0108 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.911 0.826 – 1 0.061 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.17 0.921 – 1.48 0.2 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.02 0.891 – 1.17 0.778 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 1.1 0.983 – 1.23 0.0968 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.953 0.847 – 1.07 0.429 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.947 0.836 – 1.07 0.394 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 0.927 0.798 – 1.08 0.318 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 0.903 0.739 – 1.1 0.316 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.07 0.834 – 1.38 0.59 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.894 0.756 – 1.06 0.192 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.943 0.79 – 1.12 0.513 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.01 0.997 – 1.02 0.149 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.01 0.997 – 1.02 0.161 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.01 0.998 – 1.02 0.1 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.763 0.581 – 1 0.0518 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.03 0.878 – 1.21 0.728 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.998 0.867 – 1.15 0.978 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.15 1.11 – 1.19 5.28e-16 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 1.19 1.15 – 1.24 6.06e-21 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.21 0.997 – 1.47 0.0531 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.982 0.903 – 1.07 0.663 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.974 0.892 – 1.06 0.554 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.05 1 – 1.1 0.0343 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 1.16 1.07 – 1.26 0.000294 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.11 0.995 – 1.23 0.0625 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.992 0.935 – 1.05 0.793 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.08 0.925 – 1.27 0.324 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.04 1.02 – 1.07 0.000471 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.07 1.03 – 1.1 9.86e-05 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.07 0.938 – 1.22 0.308 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.1 1.05 – 1.15 0.000113 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.03 0.96 – 1.1 0.445 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.06 1 – 1.12 0.0476 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.07 1.01 – 1.14 0.0202 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 1.08 1.01 – 1.15 0.0168 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 1.02 0.84 – 1.24 0.84 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.02 0.986 – 1.07 0.216 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 1 0.907 – 1.1 0.984 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 0.884 0.734 – 1.07 0.196 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.06 0.987 – 1.13 0.115 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.963 0.864 – 1.07 0.488 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.97 0.849 – 1.11 0.656 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.31 0.995 – 1.74 0.0547 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.978 0.959 – 0.998 0.0306 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 0.978 0.959 – 0.998 0.031 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 0.924 0.74 – 1.15 0.485 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.12 0.87 – 1.45 0.377 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.959 0.843 – 1.09 0.525 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1 0.871 – 1.16 0.969 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.08 0.906 – 1.28 0.405 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.07 0.94 – 1.22 0.303 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 0.975 0.952 – 0.998 0.0346 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.976 0.953 – 1 0.0526 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.907 0.823 – 0.999 0.0477 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 1.06 0.992 – 1.12 0.0873 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 1.05 0.987 – 1.12 0.12 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 1.05 0.97 – 1.13 0.24 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.14 0.981 – 1.32 0.087 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 1.04 0.892 – 1.22 0.605 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 1.01 0.766 – 1.33 0.944 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.02 0.867 – 1.21 0.779 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 0.979 0.752 – 1.28 0.876 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.13 0.901 – 1.41 0.294 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.09 0.909 – 1.3 0.359 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.02 0.836 – 1.25 0.819 103 1059 all phecode
284 Aplastic anemia Hematopoietic 1.05 0.949 – 1.16 0.358 435 4357 all phecode
285 Other anemias Hematopoietic 0.989 0.971 – 1.01 0.254 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.01 0.89 – 1.14 0.921 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.02 0.947 – 1.11 0.554 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.08 0.978 – 1.2 0.125 414 4147 all phecode
286 Coagulation defects Hematopoietic 0.991 0.926 – 1.06 0.79 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 0.961 0.873 – 1.06 0.415 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 0.86 0.697 – 1.06 0.159 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.02 0.904 – 1.15 0.772 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 0.915 0.715 – 1.17 0.477 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.94 0.761 – 1.16 0.57 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.958 0.863 – 1.06 0.426 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.998 0.949 – 1.05 0.947 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.952 0.796 – 1.14 0.591 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 0.943 0.704 – 1.26 0.694 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 1.01 0.957 – 1.06 0.769 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 0.969 0.877 – 1.07 0.54 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.06 0.836 – 1.34 0.644 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 0.989 0.956 – 1.02 0.526 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 0.99 0.955 – 1.03 0.611 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 0.993 0.957 – 1.03 0.7 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 0.824 0.641 – 1.06 0.129 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.05 0.977 – 1.13 0.19 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.03 0.913 – 1.17 0.612 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 1.05 1.01 – 1.09 0.0155 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 0.952 0.869 – 1.04 0.292 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.06 0.943 – 1.2 0.322 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.04 0.841 – 1.3 0.698 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.06 1.02 – 1.11 0.00969 1929 19281 all phecode
290.1 Dementias Mental Disorders 1.04 0.979 – 1.11 0.189 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 1.02 0.922 – 1.12 0.737 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 1.04 0.905 – 1.2 0.577 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.13 1.04 – 1.22 0.00401 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.07 0.833 – 1.37 0.596 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.01 0.944 – 1.09 0.721 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.886 0.741 – 1.06 0.185 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.05 0.932 – 1.19 0.408 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 0.999 0.906 – 1.1 0.982 436 4376 all phecode
292 Neurological disorders Mental Disorders 1.04 1.01 – 1.07 0.0143 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.03 0.972 – 1.08 0.356 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.956 0.823 – 1.11 0.551 190 1907 all phecode
292.3 Memory loss Mental Disorders 1.06 0.977 – 1.14 0.171 696 6978 all phecode
292.4 Altered mental status Mental Disorders 1.05 1 – 1.09 0.0396 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 1.04 0.921 – 1.16 0.563 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 1.03 0.981 – 1.07 0.263 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.05 0.977 – 1.12 0.194 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.08 1.01 – 1.16 0.027 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 1.02 0.939 – 1.11 0.597 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 1.35 1.15 – 1.58 0.000245 178 1780 all phecode
295.3 Psychosis Mental Disorders 1.04 0.887 – 1.22 0.63 169 1710 all phecode
296 Mood disorders Mental Disorders 1.02 1 – 1.04 0.0252 12372 123822 all phecode
296.1 Bipolar Mental Disorders 1 0.939 – 1.06 0.998 1059 10599 all phecode
296.2 Depression Mental Disorders 1.02 1 – 1.04 0.0196 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 1.03 0.927 – 1.15 0.562 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.19 1.06 – 1.34 0.00323 311 3070 all phecode
300 Anxiety disorders Mental Disorders 1.02 0.995 – 1.05 0.113 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 1.02 0.993 – 1.05 0.144 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1.05 0.894 – 1.24 0.53 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.02 0.944 – 1.1 0.604 707 7065 all phecode
300.13 Phobia Mental Disorders 1.07 0.974 – 1.17 0.159 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.05 0.885 – 1.25 0.562 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 0.9 0.68 – 1.19 0.463 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 1.26 1.05 – 1.51 0.013 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.896 0.733 – 1.1 0.288 113 1129 all phecode
301 Personality disorders Mental Disorders 1.1 0.983 – 1.23 0.0978 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.1 0.919 – 1.33 0.291 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.94 0.833 – 1.06 0.319 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.01 0.92 – 1.11 0.81 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 1.05 0.938 – 1.17 0.408 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 1.06 0.879 – 1.27 0.55 123 1229 all phecode
304 Adjustment reaction Mental Disorders 1.07 0.952 – 1.21 0.247 293 2936 all phecode
305.2 Eating disorder Mental Disorders 0.918 0.742 – 1.14 0.429 90 900 all phecode
306 Other mental disorder Mental Disorders 1.09 1.08 – 1.11 5.36e-44 28056 230087 all phecode
306.9 Tension headache Mental Disorders 1.02 0.903 – 1.15 0.782 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 1.01 0.801 – 1.28 0.912 76 770 all phecode
313.3 Autism Mental Disorders 0.959 0.725 – 1.27 0.773 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 1 0.899 – 1.12 0.972 351 3517 all phecode
315.1 Learning disorder Mental Disorders 0.957 0.816 – 1.12 0.589 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 0.902 0.729 – 1.12 0.346 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 1.55 1.51 – 1.6 2.42e-195 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.34 1.03 – 1.74 0.0302 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 1.37 1.34 – 1.4 1.3e-243 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 1.33 1.3 – 1.36 1.4e-141 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.7 1.58 – 1.83 5.26e-45 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 1.18 1.17 – 1.2 6.75e-108 19359 185465 all phecode
320 Meningitis Neurological 0.971 0.88 – 1.07 0.554 444 4447 all phecode
323 Encephalitis Neurological 0.955 0.853 – 1.07 0.423 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 0.87 0.679 – 1.11 0.268 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 0.978 0.868 – 1.1 0.718 292 2916 all phecode
327 Sleep disorders Neurological 0.996 0.937 – 1.06 0.889 1164 11659 all phecode
327.3 Sleep apnea Neurological 0.992 0.961 – 1.02 0.594 4428 44318 all phecode
327.4 Insomnia Neurological 0.936 0.795 – 1.1 0.422 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 0.934 0.782 – 1.11 0.447 136 1390 all phecode
331 Other cerebral degenerations Neurological 1.14 1.07 – 1.21 3.77e-05 1142 11416 all phecode
331.1 Hydrocephalus Neurological 1.09 0.992 – 1.2 0.073 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 1.17 1.06 – 1.29 0.00203 430 4298 all phecode
332 Parkinson's disease Neurological 1.04 0.978 – 1.11 0.206 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.01 0.947 – 1.09 0.699 894 8954 all phecode
333.1 Essential tremor Neurological 1.08 0.938 – 1.23 0.296 216 2157 all phecode
333.2 Myoclonus Neurological 1.12 0.915 – 1.38 0.266 96 958 all phecode
333.4 Torsion dystonia Neurological 1.02 0.896 – 1.17 0.744 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 1.01 0.964 – 1.06 0.634 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 0.988 0.821 – 1.19 0.902 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 0.919 0.807 – 1.05 0.206 245 2446 all phecode
335 Multiple sclerosis Neurological 1.01 0.957 – 1.07 0.658 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 1.01 0.89 – 1.14 0.897 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 0.995 0.792 – 1.25 0.966 72 719 all phecode
338 Pain Neurological 0.988 0.917 – 1.07 0.761 768 7692 all phecode
338.1 Acute pain Neurological 0.988 0.89 – 1.1 0.823 394 3937 all phecode
338.2 Chronic pain Neurological 1.01 0.904 – 1.12 0.917 380 3817 all phecode
339 Other headache syndromes Neurological 0.995 0.972 – 1.02 0.693 7819 78241 all phecode
340 Migraine Neurological 0.895 0.861 – 0.931 2.37e-08 2860 28602 all phecode
340.1 Migrain with aura Neurological 0.932 0.813 – 1.07 0.316 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.04 0.916 – 1.19 0.532 252 2535 all phecode
342 Hemiplegia Neurological 0.982 0.931 – 1.04 0.502 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 1.05 0.887 – 1.25 0.561 145 1450 all phecode
344 Other paralytic syndromes Neurological 1.02 0.944 – 1.11 0.575 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.03 0.998 – 1.06 0.0668 5023 50270 all phecode
345.1 Epilepsy Neurological 1.02 0.954 – 1.1 0.519 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 0.979 0.886 – 1.08 0.67 439 4385 all phecode
345.12 Partial epilepsy Neurological 1.02 0.901 – 1.16 0.748 277 2776 all phecode
345.3 Convulsions Neurological 1.09 1.04 – 1.14 0.00019 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.958 0.809 – 1.14 0.622 144 1438 all phecode
348 Other conditions of brain Neurological 1.04 0.962 – 1.12 0.346 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.08 0.949 – 1.22 0.253 268 2678 all phecode
348.4 Cerebral cysts Neurological 0.876 0.73 – 1.05 0.154 133 1350 all phecode
348.7 Coma Neurological 0.975 0.877 – 1.08 0.633 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.15 1.01 – 1.31 0.0408 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 1.1 0.993 – 1.22 0.0681 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.916 0.82 – 1.02 0.123 342 3414 all phecode
350 Abnormal movement Neurological 1.03 0.993 – 1.08 0.107 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 1.04 0.972 – 1.12 0.244 887 8852 all phecode
350.2 Abnormality of gait Neurological 1.05 0.996 – 1.1 0.0685 1596 15969 all phecode
350.3 Lack of coordination Neurological 0.944 0.849 – 1.05 0.292 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.791 0.599 – 1.04 0.0977 54 540 all phecode
351 Other peripheral nerve disorders Neurological 0.986 0.968 – 1 0.151 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 0.943 0.892 – 0.998 0.0413 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.966 0.878 – 1.06 0.482 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 0.95 0.886 – 1.02 0.15 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 1.02 0.96 – 1.09 0.514 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 0.81 0.67 – 0.979 0.0293 114 1138 all phecode
353.2 Nerve root lesions Neurological 1.06 0.807 – 1.4 0.662 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.867 0.731 – 1.03 0.1 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.01 0.951 – 1.06 0.859 1361 13648 all phecode
358 Myoneural disorders Neurological 0.959 0.834 – 1.1 0.552 211 2109 all phecode
358.1 Myasthenia gravis Neurological 0.933 0.806 – 1.08 0.356 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 1.02 0.922 – 1.12 0.761 465 4646 all phecode
359.1 Muscular dystrophies Neurological 0.917 0.762 – 1.1 0.355 122 1219 all phecode
359.2 Myopathy Neurological 1.04 0.934 – 1.17 0.449 360 3597 all phecode
360 Disorders of the globe Sense Organs 0.998 0.893 – 1.12 0.974 337 3367 all phecode
360.2 Progressive myopia Sense Organs 1.03 0.901 – 1.17 0.706 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 0.977 0.942 – 1.01 0.208 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.987 0.934 – 1.04 0.629 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 1.13 0.875 – 1.45 0.356 68 680 all phecode
362 Other retinal disorders Sense Organs 1.01 0.98 – 1.05 0.449 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.02 0.978 – 1.07 0.328 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.02 0.979 – 1.07 0.3 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.97 0.828 – 1.14 0.706 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 0.935 0.76 – 1.15 0.528 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.964 0.897 – 1.03 0.307 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 1.09 0.934 – 1.27 0.275 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.999 0.804 – 1.24 0.996 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.05 0.873 – 1.27 0.586 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.975 0.83 – 1.15 0.761 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 0.828 0.639 – 1.07 0.153 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.03 0.949 – 1.12 0.494 647 6485 all phecode
364.1 Corneal opacity Sense Organs 1.04 0.841 – 1.29 0.704 90 910 all phecode
364.2 Corneal edema Sense Organs 0.861 0.686 – 1.08 0.196 79 800 all phecode
364.4 Corneal degenerations Sense Organs 1.03 0.895 – 1.19 0.655 201 2017 all phecode
364.41 Keratoconus Sense Organs 1.13 0.905 – 1.42 0.274 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 1.09 0.948 – 1.26 0.219 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 1.12 0.914 – 1.38 0.267 100 1000 all phecode
365 Glaucoma Sense Organs 0.987 0.957 – 1.02 0.394 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 0.965 0.905 – 1.03 0.27 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 0.959 0.9 – 1.02 0.198 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.933 0.864 – 1.01 0.0827 698 6996 all phecode
366 Cataract Sense Organs 1.04 1.02 – 1.05 4.91e-07 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 0.797 0.626 – 1.01 0.0651 69 700 all phecode
366.2 Senile cataract Sense Organs 1.05 1.02 – 1.07 7.29e-05 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 1.03 0.837 – 1.27 0.787 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.04 0.996 – 1.08 0.076 2408 24092 all phecode
367.1 Myopia Sense Organs 1.01 0.948 – 1.07 0.865 1251 12519 all phecode
367.2 Astigmatism Sense Organs 1.12 0.965 – 1.3 0.136 190 1899 all phecode
367.8 Hypermetropia Sense Organs 1.04 0.913 – 1.18 0.56 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 1.06 0.985 – 1.15 0.118 719 7198 all phecode
368 Visual disturbances Sense Organs 0.964 0.927 – 1 0.0569 2962 29648 all phecode
368.1 Amblyopia Sense Organs 0.977 0.893 – 1.07 0.609 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.94 0.871 – 1.02 0.117 727 7288 all phecode
368.3 Anisometropia Sense Organs 0.882 0.745 – 1.04 0.144 154 1548 all phecode
368.4 Visual field defects Sense Organs 0.994 0.887 – 1.11 0.911 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 0.986 0.907 – 1.07 0.736 612 6115 all phecode
369 Infection of the eye Sense Organs 1.05 0.965 – 1.15 0.248 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 1.16 0.967 – 1.39 0.11 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 1.03 0.892 – 1.18 0.715 213 2128 all phecode
370 Keratitis Sense Organs 1.1 0.975 – 1.25 0.118 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 1.17 0.98 – 1.39 0.0831 141 1408 all phecode
371 Inflammation of the eye Sense Organs 1.01 0.97 – 1.05 0.722 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.966 0.879 – 1.06 0.478 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 1.01 0.965 – 1.05 0.747 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 0.975 0.906 – 1.05 0.51 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 1.02 0.995 – 1.05 0.112 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 1.02 0.958 – 1.09 0.522 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 1.03 0.981 – 1.08 0.229 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 1.05 1.01 – 1.1 0.0289 2204 22031 all phecode
375.2 Epiphora Sense Organs 1.07 1 – 1.15 0.0458 898 8969 all phecode
376 Disorders of the orbit Sense Organs 0.864 0.691 – 1.08 0.203 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.07 0.962 – 1.2 0.203 361 3618 all phecode
377.1 Optic atrophy Sense Organs 0.945 0.71 – 1.26 0.697 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.05 0.872 – 1.26 0.618 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.994 0.941 – 1.05 0.831 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.03 0.959 – 1.1 0.438 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.907 0.787 – 1.05 0.178 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 0.97 0.857 – 1.1 0.629 275 2755 all phecode
379 Other disorders of eye Sense Organs 1.03 0.996 – 1.07 0.0832 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 0.97 0.917 – 1.03 0.289 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.07 1.02 – 1.12 0.00574 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.27 1 – 1.61 0.0482 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.04 0.937 – 1.15 0.472 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.952 0.812 – 1.12 0.54 169 1690 all phecode
380 Disorders of external ear Sense Organs 1 0.923 – 1.09 0.979 642 6413 all phecode
380.1 Otitis externa Sense Organs 1.05 0.955 – 1.15 0.326 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 1.07 0.963 – 1.2 0.205 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1 0.961 – 1.05 0.833 2150 21493 all phecode
381.1 Otitis media Sense Organs 0.989 0.942 – 1.04 0.658 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.994 0.926 – 1.07 0.861 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 1.04 0.891 – 1.2 0.649 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.08 0.92 – 1.26 0.349 171 1709 all phecode
381.9 Otorrhea Sense Organs 1.08 0.956 – 1.22 0.221 281 2807 all phecode
382 Otalgia Sense Organs 1.04 0.921 – 1.16 0.56 308 3084 all phecode
383 Otosclerosis Sense Organs 1.05 0.937 – 1.19 0.378 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.02 0.965 – 1.08 0.451 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.06 0.993 – 1.13 0.0788 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.996 0.926 – 1.07 0.911 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 0.967 0.891 – 1.05 0.428 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.02 0.895 – 1.16 0.769 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.958 0.912 – 1.01 0.0939 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 0.937 0.859 – 1.02 0.137 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 0.922 0.829 – 1.03 0.136 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 0.969 0.899 – 1.04 0.407 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.994 0.964 – 1.03 0.711 4582 45806 all phecode
388 Other disorders of ear Sense Organs 1.12 0.974 – 1.29 0.11 202 2017 all phecode
389 Hearing loss Sense Organs 0.981 0.95 – 1.01 0.232 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.964 0.875 – 1.06 0.458 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 1.04 0.942 – 1.15 0.442 450 4497 all phecode
389.4 Tinnitus Sense Organs 0.888 0.811 – 0.972 0.0104 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 0.993 0.964 – 1.02 0.657 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 0.989 0.952 – 1.03 0.566 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 1.01 0.955 – 1.07 0.681 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.01 0.949 – 1.08 0.725 1058 10566 all phecode
395 Heart valve disorders Circulatory System 0.99 0.959 – 1.02 0.545 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.987 0.949 – 1.03 0.49 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.991 0.875 – 1.12 0.885 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.15 0.943 – 1.39 0.172 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.986 0.805 – 1.21 0.894 97 970 all phecode
395.6 Heart valve replaced Circulatory System 0.991 0.94 – 1.05 0.747 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 0.963 0.903 – 1.03 0.241 1048 10468 all phecode
401 Hypertension Circulatory System 1.01 1 – 1.02 0.0221 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 1.01 1 – 1.02 0.0225 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 0.993 0.947 – 1.04 0.78 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 1.16 1.04 – 1.29 0.00881 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.956 0.907 – 1.01 0.0962 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 0.967 0.813 – 1.15 0.708 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.08 1.02 – 1.14 0.00418 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 0.996 0.984 – 1.01 0.529 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.02 0.99 – 1.05 0.209 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 1 0.984 – 1.02 0.739 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 0.996 0.979 – 1.01 0.597 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 0.999 0.984 – 1.01 0.903 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.01 0.935 – 1.09 0.796 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.01 0.991 – 1.02 0.374 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1 0.946 – 1.07 0.903 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 0.97 0.925 – 1.02 0.223 1823 18228 all phecode
414.2 ASCVD Circulatory System 1.06 0.839 – 1.35 0.605 72 719 all phecode
415 Pulmonary heart disease Circulatory System 0.968 0.938 – 0.998 0.0369 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.884 0.7 – 1.12 0.297 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.973 0.894 – 1.06 0.525 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 0.938 0.851 – 1.03 0.195 448 4475 all phecode
416 Cardiomegaly Circulatory System 0.989 0.951 – 1.03 0.591 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 1 0.989 – 1.01 0.894 28599 270106 all phecode
418.1 Precordial pain Circulatory System 0.987 0.953 – 1.02 0.456 3551 35541 all phecode
420 Carditis Circulatory System 0.969 0.926 – 1.01 0.166 2106 21053 all phecode
420.1 Myocarditis Circulatory System 1.07 0.892 – 1.28 0.478 127 1267 all phecode
420.2 Pericarditis Circulatory System 0.962 0.909 – 1.02 0.177 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 1.07 0.931 – 1.23 0.344 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 0.966 0.794 – 1.17 0.728 113 1129 all phecode
420.3 Endocarditis Circulatory System 0.968 0.895 – 1.05 0.403 719 7194 all phecode
425 Cardiomyopathy Circulatory System 1.01 0.954 – 1.07 0.727 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.01 0.949 – 1.07 0.856 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.02 0.854 – 1.21 0.847 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.933 0.796 – 1.09 0.397 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 1.39 1.07 – 1.81 0.0133 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 0.996 0.972 – 1.02 0.766 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1 0.96 – 1.05 0.859 2114 21162 all phecode
426.21 First degree AV block Circulatory System 0.996 0.932 – 1.06 0.912 986 9867 all phecode
426.23 Second degree AV block Circulatory System 1.03 0.939 – 1.14 0.495 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 0.991 0.911 – 1.08 0.835 587 5868 all phecode
426.25 Other heart block Circulatory System 0.943 0.789 – 1.13 0.521 131 1318 all phecode
426.3 Bundle branch block Circulatory System 0.993 0.958 – 1.03 0.683 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 1.01 0.958 – 1.07 0.703 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 0.982 0.935 – 1.03 0.479 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.05 0.922 – 1.21 0.438 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.63 1.23 – 2.17 0.000693 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.03 0.987 – 1.07 0.178 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.03 0.985 – 1.07 0.209 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 1.01 0.997 – 1.02 0.147 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.01 0.975 – 1.05 0.561 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.03 0.983 – 1.07 0.247 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.965 0.903 – 1.03 0.304 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.02 1 – 1.04 0.0286 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.979 0.944 – 1.02 0.258 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.06 0.996 – 1.12 0.0675 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.04 0.932 – 1.16 0.471 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 1.05 0.986 – 1.13 0.123 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.03 0.96 – 1.1 0.449 952 9541 all phecode
427.6 Premature beats Circulatory System 1.06 0.972 – 1.16 0.183 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 1.06 0.873 – 1.28 0.566 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 1.05 1 – 1.1 0.0327 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.1 0.988 – 1.21 0.0849 402 4029 all phecode
427.9 Palpitations Circulatory System 0.977 0.945 – 1.01 0.173 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.02 0.989 – 1.05 0.234 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1 0.96 – 1.05 0.847 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 1.02 0.991 – 1.05 0.166 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 0.995 0.922 – 1.07 0.894 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 0.823 0.638 – 1.06 0.135 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.966 0.883 – 1.06 0.453 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.07 0.93 – 1.24 0.334 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 1.05 0.998 – 1.1 0.0588 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.03 0.958 – 1.11 0.435 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1.03 0.957 – 1.11 0.411 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 1.14 1 – 1.29 0.0462 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 1.01 0.992 – 1.04 0.209 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.1 1.04 – 1.17 0.00118 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.08 0.939 – 1.24 0.282 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.02 0.984 – 1.05 0.348 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.02 0.97 – 1.07 0.453 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 0.992 0.954 – 1.03 0.667 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 0.987 0.944 – 1.03 0.562 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 1.06 0.955 – 1.18 0.27 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.02 0.964 – 1.08 0.478 1279 12783 all phecode
440 Atherosclerosis Circulatory System 1.05 0.998 – 1.12 0.0605 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.967 0.796 – 1.18 0.736 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.08 1 – 1.16 0.0372 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 0.973 0.863 – 1.1 0.656 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.09 1.01 – 1.19 0.0368 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.12 0.985 – 1.27 0.0849 283 2827 all phecode
442 Other aneurysm Circulatory System 0.99 0.944 – 1.04 0.674 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 0.992 0.94 – 1.05 0.775 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.997 0.933 – 1.07 0.94 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.02 0.832 – 1.25 0.852 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.01 0.863 – 1.19 0.882 169 1696 all phecode
442.4 Arterial dissection Circulatory System 1.03 0.782 – 1.35 0.849 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.01 0.872 – 1.16 0.925 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 1.05 1.01 – 1.08 0.00642 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 0.96 0.904 – 1.02 0.189 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.97 0.875 – 1.08 0.565 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.05 1.02 – 1.09 0.00207 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.1 1.05 – 1.14 6.84e-06 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.16 1.09 – 1.24 1.12e-05 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.18 1.08 – 1.29 0.000151 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.955 0.89 – 1.03 0.207 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 0.908 0.785 – 1.05 0.195 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 0.931 0.839 – 1.03 0.182 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 1.05 0.918 – 1.19 0.497 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.13 1.07 – 1.19 3.16e-05 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 1.17 1.09 – 1.25 1.86e-05 868 8712 all phecode
448 Disease of capillaries Circulatory System 0.96 0.805 – 1.14 0.651 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.02 0.947 – 1.1 0.567 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.987 0.955 – 1.02 0.42 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.985 0.952 – 1.02 0.39 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.968 0.889 – 1.06 0.464 564 5645 all phecode
454 Varicose veins Circulatory System 1.02 1 – 1.04 0.0196 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1.02 1 – 1.04 0.0251 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.04 0.957 – 1.13 0.371 624 6325 all phecode
455 Hemorrhoids Circulatory System 1.01 1 – 1.03 0.055 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1 0.858 – 1.17 0.975 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.977 0.793 – 1.2 0.826 97 967 all phecode
458 Hypotension Circulatory System 0.991 0.965 – 1.02 0.535 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 0.998 0.943 – 1.06 0.935 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 0.993 0.87 – 1.13 0.915 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 0.989 0.955 – 1.02 0.537 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 0.996 0.98 – 1.01 0.665 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 1.08 0.911 – 1.29 0.36 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 0.996 0.98 – 1.01 0.666 16103 159422 all phecode
464 Acute sinusitis Respiratory 1.03 0.893 – 1.19 0.664 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.985 0.944 – 1.03 0.5 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 0.979 0.912 – 1.05 0.563 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1 0.855 – 1.17 0.985 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1 0.975 – 1.04 0.771 4654 46553 all phecode
471 Nasal polyps Respiratory 1.01 0.973 – 1.05 0.64 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.993 0.93 – 1.06 0.836 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1.06 1.02 – 1.11 0.00263 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 0.999 0.821 – 1.22 0.99 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.08 0.958 – 1.23 0.2 264 2647 all phecode
473.4 Voice disturbance Respiratory 1.01 0.953 – 1.08 0.65 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 0.992 0.944 – 1.04 0.741 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 0.975 0.894 – 1.06 0.574 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.996 0.936 – 1.06 0.893 1122 11199 all phecode
475 Chronic sinusitis Respiratory 1.03 0.986 – 1.07 0.196 2589 25882 all phecode
476 Allergic rhinitis Respiratory 0.97 0.91 – 1.03 0.359 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.02 0.982 – 1.07 0.269 2447 24452 all phecode
478 Throat pain Respiratory 0.989 0.889 – 1.1 0.845 377 3789 all phecode
479 Other upper respiratory disease Respiratory 1.01 0.982 – 1.05 0.409 4074 40737 all phecode
480 Pneumonia Respiratory 1.03 1.01 – 1.05 0.0122 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 1.03 1.01 – 1.06 0.0104 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.03 1.01 – 1.06 0.0128 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 0.992 0.804 – 1.22 0.943 93 929 all phecode
480.2 Viral pneumonia Respiratory 0.986 0.774 – 1.26 0.912 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.901 0.734 – 1.11 0.32 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.12 1.04 – 1.2 0.0021 794 7951 all phecode
481 Influenza Respiratory 1.14 1.02 – 1.28 0.0269 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.13 0.978 – 1.31 0.0954 193 1930 all phecode
495 Asthma Respiratory 1.01 0.999 – 1.02 0.0829 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 1.18 1.03 – 1.35 0.0142 250 2510 all phecode
496 Chronic airway obstruction Respiratory 1.08 1.06 – 1.11 1.14e-14 10424 101546 all phecode
496.1 Emphysema Respiratory 1.11 1.06 – 1.17 2.75e-05 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 1.09 1.05 – 1.13 2.03e-05 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.08 1.04 – 1.12 0.000118 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 1.05 0.999 – 1.1 0.0549 1885 18859 all phecode
497 Bronchitis Respiratory 1.05 0.969 – 1.14 0.231 626 6267 all phecode
500 Lung disease due to external agents Respiratory 1.07 0.967 – 1.18 0.188 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.03 0.825 – 1.3 0.769 79 784 all phecode
500.2 Pneumoconiosis Respiratory 1.08 0.945 – 1.23 0.267 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.05 0.972 – 1.14 0.209 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.07 0.996 – 1.14 0.0649 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.08 0.987 – 1.18 0.0955 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.09 0.973 – 1.22 0.138 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 0.961 0.741 – 1.25 0.763 61 610 all phecode
506 Empyema and pneumothorax Respiratory 1.03 0.966 – 1.09 0.394 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 1.04 1.01 – 1.06 0.00525 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.05 1 – 1.1 0.0371 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.03 0.992 – 1.08 0.111 2599 26031 all phecode
509.1 Respiratory failure Respiratory 1.03 0.987 – 1.08 0.161 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 1.04 0.991 – 1.09 0.109 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 1.04 0.879 – 1.23 0.651 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.05 0.946 – 1.17 0.348 386 3863 all phecode
510 Other diseases of lung Respiratory 1.1 1.02 – 1.19 0.0107 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 1.01 0.987 – 1.03 0.45 9031 90349 all phecode
512.1 Wheezing Respiratory 1.02 0.889 – 1.17 0.766 220 2196 all phecode
512.2 Painful respiration Respiratory 0.922 0.799 – 1.06 0.262 207 2075 all phecode
512.7 Shortness of breath Respiratory 1 0.974 – 1.03 0.964 5842 58498 all phecode
512.8 Cough Respiratory 1.02 0.98 – 1.06 0.363 2866 28642 all phecode
512.9 Other dyspnea Respiratory 1.04 0.967 – 1.11 0.317 914 9124 all phecode
513 Respiratory abnormalities Respiratory 0.977 0.899 – 1.06 0.584 611 6112 all phecode
513.3 Hypoventilation Respiratory 1.05 0.845 – 1.32 0.638 83 830 all phecode
513.4 Hyperventilation Respiratory 0.935 0.825 – 1.06 0.29 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 1.05 0.893 – 1.24 0.553 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 1.07 1.02 – 1.11 0.00227 2465 24673 all phecode
516 Abnormal sputum Respiratory 1.05 1.01 – 1.1 0.0217 2132 21335 all phecode
516.1 Hemoptysis Respiratory 1.05 1.01 – 1.1 0.0242 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.02 0.997 – 1.04 0.1 9366 93681 all phecode
519.2 Respiratory complications Respiratory 1.04 0.927 – 1.17 0.506 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.02 0.995 – 1.04 0.141 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.994 0.885 – 1.12 0.919 303 3049 all phecode
520 Disorders of tooth development Digestive 0.946 0.903 – 0.99 0.0167 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.1 0.829 – 1.47 0.5 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 0.952 0.912 – 0.993 0.0234 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 0.968 0.932 – 1.01 0.0931 3016 30245 all phecode
521.1 Dental caries Digestive 0.969 0.934 – 1.01 0.105 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 0.992 0.944 – 1.04 0.74 1774 17750 all phecode
522.5 Periapical abscess Digestive 1 0.946 – 1.07 0.873 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 1.01 0.956 – 1.06 0.835 1681 16812 all phecode
523.1 Gingivitis Digestive 1.1 0.914 – 1.33 0.307 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.04 0.979 – 1.1 0.208 1165 11650 all phecode
523.31 Acute periodontitis Digestive 1.03 0.949 – 1.11 0.507 666 6667 all phecode
523.32 Chronic periodontitis Digestive 1.06 0.969 – 1.15 0.21 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.99 0.885 – 1.11 0.857 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.983 0.875 – 1.1 0.777 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.96 0.922 – 0.999 0.0424 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.982 0.771 – 1.25 0.88 72 720 all phecode
526 Diseases of the jaws Digestive 0.976 0.912 – 1.04 0.481 928 9279 all phecode
526.1 Cysts of the jaws Digestive 0.937 0.838 – 1.05 0.251 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.972 0.75 – 1.26 0.828 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.06 0.924 – 1.21 0.423 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.03 0.898 – 1.18 0.681 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.985 0.809 – 1.2 0.882 110 1098 all phecode
526.9 Jaw disease NOS Digestive 0.96 0.838 – 1.1 0.558 233 2329 all phecode
527 Diseases of the salivary glands Digestive 1.01 0.935 – 1.09 0.78 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.29 1.03 – 1.62 0.0282 84 838 all phecode
527.2 Sialoadenitis Digestive 1.01 0.911 – 1.13 0.796 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 0.921 0.705 – 1.2 0.545 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.05 0.87 – 1.27 0.603 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.01 0.973 – 1.04 0.71 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 1.04 0.94 – 1.14 0.479 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.05 0.947 – 1.17 0.336 389 3884 all phecode
528.12 Oral aphthae Digestive 0.99 0.796 – 1.23 0.929 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.03 0.88 – 1.2 0.733 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 0.971 0.806 – 1.17 0.758 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 0.975 0.788 – 1.21 0.816 94 940 all phecode
528.5 Diseases of lips Digestive 0.997 0.921 – 1.08 0.936 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.02 0.909 – 1.15 0.715 308 3079 all phecode
528.7 Sialolithiasis Digestive 1.11 0.984 – 1.25 0.0914 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 1.01 0.954 – 1.07 0.679 1232 12312 all phecode
529.1 Glossitis Digestive 1.14 1.02 – 1.28 0.0246 299 2986 all phecode
530 Diseases of esophagus Digestive 1 0.992 – 1.01 0.557 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1 0.988 – 1.01 0.985 31253 272429 all phecode
530.11 GERD Digestive 0.987 0.973 – 1 0.0562 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 1.02 0.996 – 1.05 0.0977 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 1 0.981 – 1.02 0.961 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.09 1.03 – 1.14 0.00123 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.03 0.986 – 1.08 0.164 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 0.957 0.882 – 1.04 0.285 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.973 0.827 – 1.15 0.743 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.11 0.993 – 1.24 0.0673 341 3416 all phecode
530.9 Heartburn Digestive 0.973 0.93 – 1.02 0.244 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.06 1.04 – 1.09 1.92e-06 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.09 1.01 – 1.18 0.0354 637 6374 all phecode
531.2 Gastric ulcer Digestive 1.07 1.04 – 1.11 1.45e-05 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 1.07 1.03 – 1.11 0.000852 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.07 0.966 – 1.18 0.204 427 4268 all phecode
532 Dysphagia Digestive 1 0.975 – 1.03 0.968 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 1.02 1 – 1.03 0.0113 28078 261548 all phecode
535.1 Acute gastritis Digestive 0.995 0.937 – 1.06 0.861 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 1.05 0.943 – 1.17 0.372 370 3687 all phecode
535.6 Duodenitis Digestive 1.01 0.986 – 1.03 0.445 7592 75928 all phecode
535.8 Other specified gastritis Digestive 1 0.981 – 1.03 0.773 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.2 0.992 – 1.45 0.0598 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.11 0.97 – 1.26 0.131 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 0.988 0.953 – 1.02 0.498 3391 33907 all phecode
540 Appendiceal conditions Digestive 1.02 0.984 – 1.06 0.274 3088 30890 all phecode
540.1 Appendicitis Digestive 1.02 0.978 – 1.06 0.42 2895 28963 all phecode
540.11 Acute appendicitis Digestive 1.02 0.978 – 1.06 0.386 2601 26019 all phecode
550 Abdominal hernia Digestive 0.982 0.973 – 0.992 0.000513 45429 282640 all phecode
550.1 Inguinal hernia Digestive 0.963 0.947 – 0.979 6.75e-06 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 0.988 0.975 – 1 0.0629 26494 238953 all phecode
550.3 Femoral hernia Digestive 1.02 0.937 – 1.1 0.698 651 6504 all phecode
550.4 Umbilical hernia Digestive 0.987 0.954 – 1.02 0.452 3705 37072 all phecode
550.5 Ventral hernia Digestive 1.03 0.99 – 1.06 0.154 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 0.992 0.962 – 1.02 0.628 4444 44442 all phecode
555.1 Regional enteritis Digestive 0.976 0.929 – 1.02 0.324 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 1 0.965 – 1.04 0.974 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 0.992 0.907 – 1.08 0.86 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 1.04 0.971 – 1.1 0.286 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 1.02 0.939 – 1.1 0.698 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.921 0.814 – 1.04 0.186 299 2987 all phecode
557.1 Celiac disease Digestive 0.961 0.916 – 1.01 0.111 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 1 0.986 – 1.02 0.753 15492 155105 all phecode
559 Ileostomy status Digestive 0.983 0.935 – 1.03 0.511 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.02 0.99 – 1.06 0.166 3936 39337 all phecode
560.1 Paralytic ileus Digestive 1.05 0.956 – 1.15 0.326 523 5231 all phecode
560.2 Impaction of intestine Digestive 0.96 0.845 – 1.09 0.535 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.05 0.982 – 1.13 0.142 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 1.04 0.999 – 1.07 0.0558 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 1.01 0.992 – 1.02 0.339 15772 157686 all phecode
561.1 Diarrhea Digestive 1.14 1.04 – 1.26 0.00805 466 4653 all phecode
561.2 Flatulence Digestive 1.02 0.969 – 1.07 0.463 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 1.02 1.01 – 1.04 0.000173 26714 211692 all phecode
562.1 Diverticulosis Digestive 1.03 1.01 – 1.04 0.000139 26672 211642 all phecode
563 Constipation Digestive 1.02 0.995 – 1.04 0.15 10314 103140 all phecode
564 Functional digestive disorders Digestive 1.02 1 – 1.03 0.0104 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 0.997 0.97 – 1.03 0.837 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 0.992 0.943 – 1.04 0.753 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 1.03 1.01 – 1.05 0.000265 15186 151648 all phecode
565 Anal and rectal conditions Digestive 1.05 1.03 – 1.07 2.43e-08 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 1.07 1.05 – 1.1 1.22e-08 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.04 0.975 – 1.12 0.218 929 9293 all phecode
568 Other disorders of peritoneum Digestive 0.961 0.927 – 0.996 0.0307 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.969 0.934 – 1.01 0.0943 3101 30987 all phecode
569 Other disorders of intestine Digestive 1.02 0.99 – 1.05 0.185 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.881 0.743 – 1.04 0.145 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 0.945 0.861 – 1.04 0.227 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.07 1.03 – 1.11 0.000742 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 0.988 0.94 – 1.04 0.641 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.08 0.894 – 1.31 0.42 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 1.04 0.918 – 1.19 0.508 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.23 1.15 – 1.31 5.74e-10 976 9804 all phecode
571.81 Portal hypertension Digestive 1.3 1.19 – 1.43 7.28e-09 528 5285 all phecode
572 Ascites (non malignant) Digestive 1.07 1.01 – 1.13 0.0139 1544 15454 all phecode
573 Other disorders of liver Digestive 1.05 0.993 – 1.1 0.091 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 1.12 0.909 – 1.38 0.289 96 960 all phecode
573.3 Hepatomegaly Digestive 1.18 1.05 – 1.33 0.00572 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 1.11 1.03 – 1.19 0.00379 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 1.03 0.998 – 1.07 0.0681 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 0.945 0.819 – 1.09 0.444 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 0.949 0.934 – 0.965 9.08e-10 15607 156123 all phecode
574.1 Cholelithiasis Digestive 0.946 0.929 – 0.963 1e-09 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.998 0.946 – 1.05 0.931 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.936 0.91 – 0.962 3.81e-06 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 0.977 0.938 – 1.02 0.253 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.975 0.937 – 1.01 0.211 2748 27523 all phecode
575 Other biliary tract disease Digestive 0.967 0.935 – 1 0.0476 3867 38724 all phecode
575.1 Cholangitis Digestive 1.01 0.923 – 1.11 0.765 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 0.999 0.927 – 1.08 0.981 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.874 0.791 – 0.965 0.00756 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 0.939 0.889 – 0.993 0.0259 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 0.979 0.918 – 1.04 0.523 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.09 0.972 – 1.22 0.142 348 3488 all phecode
577 Diseases of pancreas Digestive 1.01 0.971 – 1.05 0.611 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 0.991 0.947 – 1.04 0.714 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 1.15 1.05 – 1.26 0.00277 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.05 0.939 – 1.16 0.422 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 1.02 1.01 – 1.04 0.0011 20626 206278 all phecode
578.1 Hematemesis Digestive 1.08 1.03 – 1.13 0.00111 1958 19564 all phecode
578.2 Blood in stool Digestive 1.09 1.05 – 1.14 1.65e-05 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.01 0.99 – 1.03 0.368 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.04 1.01 – 1.07 0.00369 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.02 0.97 – 1.08 0.409 1548 15498 all phecode
579.2 Splenomegaly Digestive 0.995 0.901 – 1.1 0.92 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.965 0.917 – 1.02 0.167 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.997 0.946 – 1.05 0.909 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 0.987 0.927 – 1.05 0.697 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.34 1.04 – 1.72 0.0228 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.921 0.767 – 1.11 0.379 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.976 0.911 – 1.05 0.496 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.998 0.907 – 1.1 0.967 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.997 0.875 – 1.14 0.968 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.988 0.869 – 1.12 0.85 253 2529 all phecode
585 Renal failure Genitourinary 0.996 0.971 – 1.02 0.735 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 1.02 0.988 – 1.05 0.247 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 1 0.951 – 1.06 0.908 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.964 0.926 – 1 0.075 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 0.885 0.806 – 0.971 0.01 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 0.952 0.919 – 0.987 0.00693 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.04 0.902 – 1.2 0.599 208 2089 all phecode
586.11 Small kidney Genitourinary 1.05 0.9 – 1.22 0.553 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 0.947 0.894 – 1 0.0614 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.893 0.711 – 1.12 0.333 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.921 0.861 – 0.986 0.0183 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 0.888 0.797 – 0.99 0.0315 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.21 0.981 – 1.5 0.0746 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 0.974 0.8 – 1.19 0.794 116 1158 all phecode
590 Pyelonephritis Genitourinary 0.979 0.924 – 1.04 0.458 1328 13285 all phecode
591 Urinary tract infection Genitourinary 0.991 0.973 – 1.01 0.334 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 0.977 0.94 – 1.01 0.222 2966 29661 all phecode
592.1 Cystitis Genitourinary 0.98 0.943 – 1.02 0.307 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 1.03 0.868 – 1.22 0.73 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 0.972 0.907 – 1.04 0.43 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.864 0.757 – 0.985 0.0287 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.878 0.746 – 1.03 0.115 165 1662 all phecode
593 Hematuria Genitourinary 0.997 0.981 – 1.01 0.686 16068 160204 all phecode
594 Urinary calculus Genitourinary 0.92 0.897 – 0.944 2.64e-10 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 0.931 0.898 – 0.966 0.000119 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 0.912 0.847 – 0.982 0.0143 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 0.919 0.881 – 0.958 6.71e-05 2401 24024 all phecode
594.8 Renal colic Genitourinary 0.915 0.874 – 0.958 0.000134 2050 20500 all phecode
595 Hydronephrosis Genitourinary 0.969 0.925 – 1.02 0.192 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 0.954 0.935 – 0.975 1.18e-05 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 0.925 0.883 – 0.968 0.000913 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 1 0.952 – 1.05 0.959 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.973 0.942 – 1.01 0.108 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.969 0.935 – 1 0.0805 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 0.948 0.752 – 1.2 0.652 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 0.976 0.942 – 1.01 0.17 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.08 0.955 – 1.21 0.228 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.974 0.959 – 0.989 0.000624 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 1.07 0.914 – 1.26 0.398 166 1670 all phecode
599.2 Retention of urine Genitourinary 0.956 0.932 – 0.98 0.000416 6718 67168 all phecode
599.3 Dysuria Genitourinary 0.973 0.916 – 1.03 0.361 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 0.987 0.965 – 1.01 0.247 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 0.962 0.931 – 0.994 0.0194 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 1.15 0.941 – 1.4 0.174 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 0.977 0.757 – 1.26 0.857 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 0.909 0.867 – 0.952 5.83e-05 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 0.951 0.933 – 0.97 8.11e-07 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.927 0.886 – 0.97 0.00098 2081 20818 all phecode
601.1 Prostatitis Genitourinary 0.915 0.868 – 0.964 0.000827 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 0.896 0.782 – 1.03 0.112 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 0.952 0.889 – 1.02 0.159 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 0.95 0.732 – 1.23 0.7 59 588 all phecode
601.4 Balanoposthitis Genitourinary 0.952 0.844 – 1.07 0.428 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.992 0.882 – 1.11 0.887 303 3019 all phecode
602 Other disorders of prostate Genitourinary 0.905 0.857 – 0.957 0.000437 1341 13408 all phecode
603 Other disorders of testis Genitourinary 0.974 0.932 – 1.02 0.249 2150 21512 all phecode
603.1 Hydrocele Genitourinary 0.951 0.899 – 1.01 0.0749 1339 13402 all phecode
604 Disorders of penis Genitourinary 0.946 0.913 – 0.981 0.00263 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.943 0.907 – 0.981 0.00376 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.11 0.979 – 1.25 0.106 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 1.01 0.967 – 1.04 0.797 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.15 0.999 – 1.33 0.0524 214 2138 all phecode
609.1 Infertility, male Genitourinary 1.22 0.934 – 1.58 0.146 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 1.09 0.929 – 1.27 0.3 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 1.01 0.965 – 1.05 0.775 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 0.935 0.874 – 1 0.0541 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.04 0.924 – 1.17 0.527 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 1 0.889 – 1.13 0.991 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 1.03 0.976 – 1.09 0.273 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.04 0.96 – 1.12 0.357 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.02 0.965 – 1.07 0.524 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 1.14 0.863 – 1.49 0.365 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 1.01 0.962 – 1.07 0.606 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.03 0.959 – 1.1 0.433 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.04 0.966 – 1.11 0.321 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 1.07 0.84 – 1.37 0.578 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 1.01 0.957 – 1.06 0.77 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.04 0.961 – 1.12 0.347 720 7210 all phecode
613.5 Mastodynia Genitourinary 0.871 0.688 – 1.1 0.252 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.984 0.91 – 1.06 0.688 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 1.03 0.92 – 1.16 0.583 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 0.905 0.786 – 1.04 0.165 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.986 0.959 – 1.01 0.314 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.942 0.904 – 0.981 0.00422 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.963 0.897 – 1.03 0.304 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.836 0.648 – 1.08 0.171 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.934 0.845 – 1.03 0.185 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.05 0.938 – 1.17 0.412 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.09 0.965 – 1.24 0.162 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.03 0.987 – 1.07 0.186 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.05 0.988 – 1.11 0.122 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.01 0.913 – 1.12 0.858 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.06 0.985 – 1.15 0.115 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.96 0.848 – 1.09 0.528 274 2737 all phecode
615 Endometriosis Genitourinary 0.98 0.948 – 1.01 0.214 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 0.994 0.883 – 1.12 0.922 304 3037 all phecode
618 Genital prolapse Genitourinary 0.962 0.944 – 0.981 9.35e-05 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 0.976 0.953 – 1 0.0491 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.951 0.924 – 0.978 0.000451 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.969 0.884 – 1.06 0.498 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.907 0.837 – 0.982 0.0157 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.997 0.975 – 1.02 0.806 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.996 0.922 – 1.08 0.914 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 0.999 0.963 – 1.04 0.948 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.99 0.952 – 1.03 0.605 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.01 0.959 – 1.06 0.765 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.05 0.994 – 1.11 0.0818 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 0.979 0.774 – 1.24 0.856 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 0.96 0.903 – 1.02 0.202 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 0.982 0.963 – 1 0.0878 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.982 0.959 – 1.01 0.125 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.971 0.937 – 1.01 0.102 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 0.968 0.914 – 1.03 0.276 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 1.01 0.938 – 1.09 0.812 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 1.03 0.9 – 1.18 0.671 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.944 0.856 – 1.04 0.255 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 1 0.973 – 1.03 0.999 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.03 0.994 – 1.07 0.1 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 1.01 0.954 – 1.08 0.664 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.993 0.977 – 1.01 0.425 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.991 0.973 – 1.01 0.3 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.979 0.805 – 1.19 0.83 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 0.98 0.959 – 1 0.0584 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 1.04 0.997 – 1.09 0.0665 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 1.01 0.976 – 1.04 0.576 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 1.01 0.958 – 1.06 0.816 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.964 0.822 – 1.13 0.649 159 1587 all phecode
626.8 Infertility, female Genitourinary 1.05 0.995 – 1.11 0.0746 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.99 0.97 – 1.01 0.352 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 0.99 0.969 – 1.01 0.383 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 1.1 0.942 – 1.28 0.233 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.959 0.901 – 1.02 0.186 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 1.03 0.919 – 1.16 0.59 310 3097 all phecode
628 Ovarian cyst Genitourinary 0.98 0.951 – 1.01 0.19 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.04 1.01 – 1.07 0.00706 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.991 0.932 – 1.05 0.767 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.18 1.06 – 1.32 0.00354 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.994 0.948 – 1.04 0.797 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.995 0.928 – 1.07 0.887 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1 0.946 – 1.06 0.935 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.03 0.991 – 1.08 0.127 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 1.03 0.95 – 1.12 0.462 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.07 1 – 1.14 0.0475 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 1.08 0.843 – 1.39 0.538 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.939 0.882 – 0.999 0.0453 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.01 0.9 – 1.14 0.834 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.992 0.863 – 1.14 0.914 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.917 0.777 – 1.08 0.306 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.04 0.98 – 1.1 0.2 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.997 0.954 – 1.04 0.889 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.1 0.855 – 1.4 0.472 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.952 0.841 – 1.08 0.434 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.888 0.73 – 1.08 0.231 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.953 0.821 – 1.11 0.522 193 1922 all phecode
650 Normal delivery Pregnancy Complications 1.04 0.992 – 1.09 0.105 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 0.973 0.871 – 1.09 0.623 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1.03 0.982 – 1.09 0.218 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.02 0.966 – 1.08 0.471 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 0.949 0.758 – 1.19 0.65 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.997 0.965 – 1.03 0.835 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.05 0.86 – 1.28 0.635 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 1.02 0.981 – 1.07 0.274 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.971 0.888 – 1.06 0.51 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.994 0.965 – 1.02 0.709 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.03 0.988 – 1.07 0.165 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1 0.852 – 1.18 0.985 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.935 0.826 – 1.06 0.289 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.02 0.783 – 1.33 0.889 63 624 all phecode
679 Complications of in utero procedures Dermatologic 1.03 0.785 – 1.35 0.833 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.02 0.995 – 1.04 0.128 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.05 0.965 – 1.14 0.253 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.982 0.896 – 1.08 0.695 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.02 0.991 – 1.05 0.197 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.02 0.991 – 1.05 0.184 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.02 0.991 – 1.05 0.184 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.07 0.98 – 1.16 0.134 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.01 0.957 – 1.07 0.678 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 0.992 0.95 – 1.04 0.728 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 1.07 0.987 – 1.17 0.0992 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 1.04 0.935 – 1.16 0.454 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1.01 0.92 – 1.1 0.899 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.04 0.993 – 1.09 0.102 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 0.928 0.82 – 1.05 0.239 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 1.15 0.944 – 1.39 0.169 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 0.99 0.953 – 1.03 0.593 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.01 0.979 – 1.03 0.689 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 1.02 0.797 – 1.29 0.904 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.947 0.716 – 1.25 0.705 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 1.08 0.897 – 1.3 0.417 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 1.06 0.99 – 1.13 0.0982 986 9854 all phecode
694.1 Vitiligo Dermatologic 0.94 0.717 – 1.23 0.651 60 599 all phecode
694.2 Other dyschromia Dermatologic 1.06 0.987 – 1.14 0.105 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 1.02 0.84 – 1.23 0.868 117 1170 all phecode
695 Erythematous conditions Dermatologic 1.01 0.97 – 1.06 0.593 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 1.29 1.06 – 1.57 0.0124 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 0.969 0.816 – 1.15 0.716 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 0.929 0.711 – 1.21 0.587 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.896 0.711 – 1.13 0.353 73 727 all phecode
695.3 Rosacea Dermatologic 1.12 1 – 1.26 0.0434 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.05 0.952 – 1.17 0.308 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.995 0.829 – 1.19 0.957 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.08 0.969 – 1.21 0.16 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 1.02 0.945 – 1.1 0.645 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 1 0.878 – 1.14 0.984 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 0.962 0.764 – 1.21 0.743 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 0.9 0.818 – 0.991 0.0312 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 1.02 0.978 – 1.07 0.333 2252 22509 all phecode
696.4 Psoriasis Dermatologic 1.02 0.98 – 1.07 0.294 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.02 0.974 – 1.08 0.347 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 0.969 0.897 – 1.05 0.428 706 7052 all phecode
697 Sarcoidosis Dermatologic 0.926 0.846 – 1.01 0.0934 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 1.04 0.964 – 1.12 0.325 782 7814 all phecode
700 Corns and callosities Dermatologic 1.09 0.967 – 1.23 0.156 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.03 0.995 – 1.06 0.104 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 0.922 0.738 – 1.15 0.476 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.02 0.977 – 1.06 0.362 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.06 0.808 – 1.38 0.683 61 610 all phecode
701.4 Keloid scar Dermatologic 0.99 0.86 – 1.14 0.892 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 0.993 0.9 – 1.09 0.886 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.09 0.899 – 1.32 0.383 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.02 0.987 – 1.04 0.288 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 1.02 0.98 – 1.06 0.329 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 1.01 0.97 – 1.05 0.718 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 0.935 0.839 – 1.04 0.22 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 0.974 0.911 – 1.04 0.442 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 1.01 0.98 – 1.04 0.557 5267 52727 all phecode
704.1 Alopecia Dermatologic 1.12 0.923 – 1.36 0.252 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.907 0.721 – 1.14 0.402 76 759 all phecode
705 Disorders of sweat glands Dermatologic 1.21 1.06 – 1.39 0.00632 228 2287 all phecode
705.3 Hidradenitis Dermatologic 1.17 1 – 1.36 0.0445 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 1.01 0.932 – 1.1 0.768 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 1.02 1 – 1.05 0.0498 8317 83195 all phecode
706.1 Acne Dermatologic 1.2 0.956 – 1.51 0.116 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 1.03 1 – 1.05 0.0273 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 1.03 0.978 – 1.07 0.298 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 1.07 1 – 1.15 0.0407 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.985 0.951 – 1.02 0.401 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 0.953 0.869 – 1.04 0.301 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 0.958 0.82 – 1.12 0.594 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.04 0.806 – 1.34 0.77 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.99 0.952 – 1.03 0.633 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.983 0.904 – 1.07 0.685 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 0.976 0.894 – 1.06 0.581 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.846 0.729 – 0.982 0.0284 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.05 0.944 – 1.16 0.381 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.08 0.981 – 1.2 0.112 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.14 1.01 – 1.27 0.0268 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.01 0.807 – 1.27 0.904 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.916 0.777 – 1.08 0.297 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 0.831 0.65 – 1.06 0.139 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1 0.973 – 1.03 0.864 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.997 0.966 – 1.03 0.841 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.976 0.928 – 1.03 0.347 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.893 0.742 – 1.07 0.231 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.977 0.899 – 1.06 0.575 618 6177 all phecode
716 Other arthropathies Musculoskeletal 1.03 1.01 – 1.04 5.5e-06 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.04 1 – 1.08 0.0295 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.03 1.01 – 1.04 0.00163 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.03 1.01 – 1.04 6.91e-06 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.05 0.991 – 1.12 0.0934 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 1.01 0.978 – 1.05 0.489 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 0.995 0.972 – 1.02 0.683 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.983 0.955 – 1.01 0.257 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.04 0.897 – 1.21 0.596 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 0.908 0.813 – 1.01 0.0884 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 0.997 0.976 – 1.02 0.793 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.07 0.973 – 1.17 0.172 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.01 0.972 – 1.05 0.604 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.27 0.993 – 1.61 0.0571 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.996 0.965 – 1.03 0.808 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 1.05 0.962 – 1.15 0.264 517 5173 all phecode
723.1 Torticollis Musculoskeletal 1.08 0.89 – 1.31 0.433 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1 0.958 – 1.05 0.896 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 0.982 0.887 – 1.09 0.722 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 0.997 0.901 – 1.1 0.95 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 0.875 0.672 – 1.14 0.321 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.02 0.968 – 1.07 0.467 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.999 0.982 – 1.02 0.878 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 0.997 0.976 – 1.02 0.751 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 0.963 0.86 – 1.08 0.516 334 3336 all phecode
726.3 Bursitis Musculoskeletal 1.02 0.947 – 1.09 0.664 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.02 0.993 – 1.04 0.173 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.989 0.95 – 1.03 0.574 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 1 0.82 – 1.22 0.996 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.03 0.991 – 1.07 0.135 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 0.988 0.908 – 1.08 0.779 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.1 0.983 – 1.23 0.0962 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.999 0.842 – 1.19 0.992 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.16 1.12 – 1.2 2.21e-17 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.992 0.896 – 1.1 0.876 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 1.14 1.1 – 1.18 1.12e-14 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.17 1.13 – 1.21 4.04e-19 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 1 0.979 – 1.03 0.717 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.931 0.873 – 0.994 0.0318 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 1.14 0.929 – 1.39 0.211 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.95 0.839 – 1.07 0.411 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.972 0.855 – 1.1 0.656 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 0.996 0.906 – 1.1 0.939 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.922 0.801 – 1.06 0.26 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.02 0.78 – 1.34 0.875 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 1 0.956 – 1.05 0.871 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 0.988 0.878 – 1.11 0.841 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.04 0.955 – 1.14 0.343 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 1.08 0.904 – 1.3 0.386 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.08 1.01 – 1.14 0.0151 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 0.883 0.733 – 1.06 0.193 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 1 0.98 – 1.02 0.936 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 1.05 0.899 – 1.22 0.564 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 0.983 0.955 – 1.01 0.246 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.975 0.93 – 1.02 0.293 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 1 0.952 – 1.06 0.892 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1 0.975 – 1.03 0.994 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 1.03 0.976 – 1.08 0.31 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 0.947 0.831 – 1.08 0.417 248 2476 all phecode
737 Curvature of spine Musculoskeletal 1 0.945 – 1.07 0.878 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.01 0.949 – 1.08 0.739 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.07 1.02 – 1.12 0.00583 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.06 1 – 1.12 0.0335 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 1.05 0.955 – 1.15 0.323 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 1.01 1 – 1.03 0.03 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.02 1 – 1.03 0.0368 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.02 0.997 – 1.04 0.0903 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.01 0.905 – 1.13 0.843 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.921 0.846 – 1 0.0582 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.01 0.994 – 1.03 0.192 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.02 0.982 – 1.05 0.353 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 1.09 0.889 – 1.33 0.418 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 1.05 0.967 – 1.14 0.246 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 1.03 0.88 – 1.21 0.683 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 1.03 0.971 – 1.08 0.358 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 0.87 0.72 – 1.05 0.151 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 0.909 0.688 – 1.2 0.5 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.04 0.998 – 1.08 0.0653 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 1.1 0.98 – 1.23 0.11 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.954 0.768 – 1.19 0.672 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1 0.911 – 1.1 0.997 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 1.04 0.993 – 1.09 0.0969 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.01 0.983 – 1.03 0.597 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 1 0.977 – 1.03 0.812 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 1.01 0.981 – 1.04 0.531 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1.01 0.925 – 1.11 0.797 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 1.12 1.02 – 1.23 0.0156 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.956 0.889 – 1.03 0.219 815 8144 all phecode
745 Pain in joint Musculoskeletal 1.03 1.01 – 1.05 0.0136 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.995 0.957 – 1.03 0.807 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.999 0.96 – 1.04 0.967 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.897 0.824 – 0.977 0.013 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.928 0.813 – 1.06 0.271 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.03 0.979 – 1.08 0.278 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.969 0.823 – 1.14 0.702 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.03 0.778 – 1.37 0.832 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.05 0.93 – 1.18 0.451 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.98 0.905 – 1.06 0.61 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.995 0.886 – 1.12 0.926 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.04 0.889 – 1.21 0.658 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.959 0.86 – 1.07 0.457 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.962 0.838 – 1.1 0.582 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.991 0.825 – 1.19 0.925 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.03 0.976 – 1.08 0.29 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.08 1 – 1.17 0.0431 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.09 0.987 – 1.2 0.089 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.06 0.922 – 1.22 0.418 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.01 0.937 – 1.08 0.858 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.977 0.883 – 1.08 0.651 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.06 0.942 – 1.18 0.353 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.04 0.932 – 1.17 0.455 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 1.08 0.948 – 1.23 0.247 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 1.1 0.951 – 1.27 0.198 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.945 0.751 – 1.19 0.629 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.842 0.701 – 1.01 0.0648 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.823 0.646 – 1.05 0.115 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.956 0.788 – 1.16 0.646 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.01 0.91 – 1.11 0.896 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.93 0.805 – 1.07 0.325 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.09 0.93 – 1.28 0.281 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.19 0.97 – 1.45 0.0956 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.939 0.861 – 1.02 0.151 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.929 0.741 – 1.17 0.525 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.966 0.875 – 1.07 0.495 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.1 0.924 – 1.3 0.29 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.3 0.997 – 1.7 0.0523 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.904 0.787 – 1.04 0.155 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.03 0.833 – 1.27 0.789 96 959 all phecode
760 Back pain Symptoms 0.982 0.963 – 1 0.0713 11126 111353 all phecode
761 Cervicalgia Symptoms 0.975 0.928 – 1.02 0.31 1791 17901 all phecode
764 Sciatica Symptoms 1.03 0.983 – 1.07 0.248 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.03 0.966 – 1.09 0.39 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 0.964 0.888 – 1.05 0.378 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.999 0.932 – 1.07 0.967 870 8687 all phecode
771.1 Swelling of limb Symptoms 1.02 0.989 – 1.05 0.204 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 1.02 0.942 – 1.11 0.613 659 6581 all phecode
773 Pain in limb Symptoms 1.01 0.98 – 1.03 0.634 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 1.27 1.09 – 1.49 0.00263 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.01 0.966 – 1.06 0.601 1870 18715 all phecode
782.3 Edema Symptoms 1.02 0.969 – 1.07 0.468 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 1.12 0.962 – 1.3 0.146 175 1748 all phecode
783 Fever of unknown origin Symptoms 0.992 0.959 – 1.02 0.614 3911 39105 all phecode
785 Abdominal pain Symptoms 0.987 0.977 – 0.998 0.0163 40080 301686 all phecode
788 Syncope and collapse Symptoms 0.994 0.973 – 1.02 0.589 9069 90813 all phecode
789 Nausea and vomiting Symptoms 0.975 0.956 – 0.994 0.00971 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.01 0.853 – 1.19 0.928 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 1.01 0.81 – 1.27 0.906 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 0.971 0.946 – 0.996 0.0256 6357 63635 all phecode
791 Gangrene Symptoms 1.03 0.943 – 1.12 0.517 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1.06 0.859 – 1.32 0.567 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.1 0.927 – 1.32 0.268 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.02 0.933 – 1.11 0.7 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.962 0.802 – 1.16 0.681 120 1198 all phecode
797 Shock Symptoms 1.03 0.884 – 1.21 0.677 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 1.01 0.828 – 1.22 0.947 102 1020 all phecode
798 Malaise and fatigue Symptoms 0.982 0.948 – 1.02 0.31 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 0.847 0.779 – 0.921 0.000104 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 1.07 1.04 – 1.1 7.41e-08 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.07 1.02 – 1.12 0.00645 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.04 0.891 – 1.21 0.622 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.07 1.02 – 1.11 0.00477 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 1.08 1.01 – 1.17 0.032 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.05 1.01 – 1.1 0.0281 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.04 0.993 – 1.09 0.0935 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 1.07 0.994 – 1.16 0.0711 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 1.06 1.04 – 1.09 1.09e-07 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.08 1.02 – 1.13 0.00478 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.06 1.03 – 1.09 0.000165 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.11 1.05 – 1.17 8.17e-05 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 1.07 1.03 – 1.11 0.000297 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.03 0.978 – 1.09 0.233 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 1.13 1.05 – 1.21 0.00115 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.01 0.958 – 1.07 0.626 1300 12998 all phecode
817 Concussion Injuries & Poisonings 1.12 0.982 – 1.28 0.0914 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.09 0.996 – 1.19 0.0624 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.12 1.08 – 1.17 1.27e-09 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 1.07 1.02 – 1.12 0.00943 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 1.1 1.05 – 1.15 3.62e-05 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 1.03 1.01 – 1.05 0.00123 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.04 0.95 – 1.14 0.407 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 1.03 0.938 – 1.13 0.525 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.99 0.962 – 1.02 0.496 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.04 0.883 – 1.23 0.629 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 0.978 0.892 – 1.07 0.637 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.04 0.995 – 1.1 0.0779 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.985 0.929 – 1.04 0.615 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.07 1.03 – 1.11 0.000436 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.02 0.988 – 1.06 0.188 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 0.909 0.708 – 1.17 0.456 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.14 1.1 – 1.18 1.85e-13 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.09 0.967 – 1.24 0.153 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 1.07 0.924 – 1.24 0.366 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.15 1.11 – 1.2 2.74e-13 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.24 1.08 – 1.44 0.0029 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 1.09 0.855 – 1.4 0.475 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.07 1.04 – 1.11 4.05e-05 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.19 0.899 – 1.57 0.226 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.879 0.709 – 1.09 0.242 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.07 0.916 – 1.25 0.388 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 0.989 0.901 – 1.09 0.812 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 1.03 0.902 – 1.18 0.66 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 0.914 0.78 – 1.07 0.261 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.13 0.956 – 1.33 0.153 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.11 1.05 – 1.18 0.000179 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.04 1.01 – 1.07 0.0223 4260 42663 all phecode
916 Contusion Injuries & Poisonings 1.06 1 – 1.12 0.0417 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 1.04 0.895 – 1.22 0.585 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.02 0.92 – 1.13 0.696 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 1.02 0.892 – 1.16 0.796 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.06 1.01 – 1.1 0.0182 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.02 0.893 – 1.17 0.731 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.839 0.69 – 1.02 0.0769 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.985 0.903 – 1.07 0.73 550 5509 all phecode
947 Urticaria Injuries & Poisonings 1.01 0.906 – 1.12 0.889 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 1.12 1.01 – 1.24 0.0376 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.03 0.931 – 1.13 0.592 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.22 1.08 – 1.39 0.00162 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.11 1.01 – 1.21 0.0343 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.08 0.824 – 1.42 0.571 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.29 1.03 – 1.63 0.0299 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.979 0.964 – 0.994 0.00672 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.984 0.968 – 1 0.0552 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 0.987 0.893 – 1.09 0.792 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.962 0.896 – 1.03 0.28 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.889 0.8 – 0.988 0.0286 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 0.887 0.798 – 0.986 0.0261 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.04 0.902 – 1.19 0.615 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.977 0.865 – 1.1 0.709 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.973 0.861 – 1.1 0.654 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.01 0.986 – 1.04 0.378 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.936 0.88 – 0.996 0.0355 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.2 1.09 – 1.32 0.000138 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.14 1.03 – 1.27 0.0105 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.09 0.997 – 1.2 0.0568 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.997 0.917 – 1.08 0.946 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.17 1.12 – 1.23 6.48e-11 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.11 0.955 – 1.28 0.179 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.13 1 – 1.28 0.0484 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.14 0.915 – 1.41 0.248 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.19 0.987 – 1.44 0.0682 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.15 0.944 – 1.41 0.164 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1 0.784 – 1.28 0.981 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.875 0.669 – 1.14 0.327 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.05 0.914 – 1.2 0.509 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.15 1.06 – 1.24 0.000571 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.28 1.11 – 1.48 0.000678 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 0.897 0.686 – 1.17 0.424 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.06 0.867 – 1.31 0.548 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 1.08 0.893 – 1.31 0.429 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.05 0.848 – 1.31 0.642 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.07 1.03 – 1.11 0.000861 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.01 0.971 – 1.05 0.675 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 1.01 0.971 – 1.05 0.675 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 1.01 0.96 – 1.07 0.62 1401 22216 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.02 0.921 – 1.14 0.673 372 6809 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.967 0.751 – 1.24 0.794 60 1596 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 0.967 0.802 – 1.17 0.722 110 2166 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 0.704 0.411 – 1.21 0.203 13 136 exclusion phecode
010 Tuberculosis Infectious Diseases 0.856 0.577 – 1.27 0.438 24 417 exclusion phecode
038 Septicemia Infectious Diseases 0.954 0.866 – 1.05 0.343 418 10517 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 0.971 0.789 – 1.2 0.78 91 2095 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 0.849 0.634 – 1.14 0.272 45 1255 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 0.988 0.941 – 1.04 0.63 1737 30511 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 0.991 0.898 – 1.09 0.864 411 8086 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.01 0.895 – 1.14 0.848 271 4233 exclusion phecode
041.4 E. coli Infectious Diseases 0.99 0.889 – 1.1 0.854 348 6821 exclusion phecode
053 Herpes zoster Infectious Diseases 1.07 0.827 – 1.39 0.593 57 985 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.76 1.05 – 2.96 0.0311 15 245 exclusion phecode
054 Herpes simplex Infectious Diseases 1.07 0.752 – 1.53 0.701 34 523 exclusion phecode
070 Viral hepatitis Infectious Diseases 0.94 0.77 – 1.15 0.542 103 1464 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 0.889 0.564 – 1.4 0.611 18 179 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.83 0.547 – 1.26 0.381 22 346 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 0.842 0.589 – 1.21 0.348 30 666 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.33 0.96 – 1.84 0.0868 41 718 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 0.981 0.756 – 1.27 0.883 60 1102 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.968 0.7 – 1.34 0.844 43 325 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.781 0.529 – 1.15 0.212 33 251 exclusion phecode
078 Viral warts & HPV Infectious Diseases 1.07 0.934 – 1.23 0.319 214 2609 exclusion phecode
079 Viral infection Infectious Diseases 0.926 0.848 – 1.01 0.0852 541 7180 exclusion phecode
079.1 Varicella infection Infectious Diseases 1.62 0.955 – 2.76 0.0735 15 164 exclusion phecode
080 Postoperative infection Infectious Diseases 1.01 0.934 – 1.08 0.868 743 11444 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.03 0.927 – 1.15 0.561 351 6132 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.23 0.724 – 2.11 0.439 11 166 exclusion phecode
1000 Burns Injuries & Poisonings 1.19 0.963 – 1.47 0.107 91 1490 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 0.933 0.815 – 1.07 0.319 227 2980 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 0.999 0.932 – 1.07 0.97 851 13887 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.22 0.827 – 1.8 0.316 23 776 exclusion phecode
1005 Other symptoms Injuries & Poisonings 0.947 0.808 – 1.11 0.504 159 3647 exclusion phecode
1006 Crushing injury Injuries & Poisonings 1.26 0.904 – 1.75 0.174 36 639 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 1.55 1.18 – 2.04 0.00174 53 661 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.1 0.955 – 1.27 0.186 192 2561 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 1.01 0.956 – 1.06 0.819 1559 21328 exclusion phecode
1010 Other tests Injuries & Poisonings 0.983 0.926 – 1.04 0.586 1120 15051 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.997 0.947 – 1.05 0.895 1581 22966 exclusion phecode
1012 Late effect Injuries & Poisonings 1.41 0.886 – 2.25 0.147 18 271 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.12 0.786 – 1.61 0.52 27 779 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.13 0.693 – 1.86 0.615 14 148 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 0.927 0.855 – 1.01 0.0685 611 10796 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.02 0.984 – 1.06 0.285 3269 41342 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.93 0.729 – 1.19 0.558 66 730 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.935 0.731 – 1.2 0.59 65 701 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.889 0.567 – 1.39 0.609 19 205 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.05 0.764 – 1.44 0.77 37 349 exclusion phecode
112 Candidiasis Infectious Diseases 1.02 0.902 – 1.15 0.786 280 5335 exclusion phecode
117 Mycoses Infectious Diseases 1.27 0.923 – 1.74 0.143 43 663 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.18 0.807 – 1.74 0.387 29 402 exclusion phecode
130 Spirochetal infection Infectious Diseases 1 0.649 – 1.55 0.991 19 202 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 1.13 0.724 – 1.77 0.585 20 172 exclusion phecode
134 Helminthiases Infectious Diseases 1.05 0.749 – 1.46 0.795 35 310 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.13 0.781 – 1.62 0.525 30 255 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.83 0.588 – 1.17 0.29 34 490 exclusion phecode
145 Cancer of mouth Neoplasms 1.26 1.02 – 1.54 0.0292 96 1703 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.42 1.06 – 1.92 0.0197 45 821 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.958 0.617 – 1.49 0.847 20 274 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 0.985 0.437 – 2.22 0.97 3 132 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.38 1.12 – 1.69 0.00217 94 1630 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.13 0.808 – 1.57 0.483 38 681 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.44 1.06 – 1.95 0.0199 36 655 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.39 0.821 – 2.34 0.222 13 129 exclusion phecode
150 Cancer of esophagus Neoplasms 1.57 1.2 – 2.05 0.000952 52 1879 exclusion phecode
151 Cancer of stomach Neoplasms 1.36 1 – 1.85 0.05 40 1341 exclusion phecode
153 Colorectal cancer Neoplasms 1.06 0.985 – 1.14 0.125 797 11333 exclusion phecode
153.2 Colon cancer Neoplasms 1.04 0.954 – 1.14 0.35 505 7596 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.11 1 – 1.23 0.049 379 5421 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.641 0.415 – 0.99 0.0447 16 943 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.594 0.33 – 1.07 0.0818 7 392 exclusion phecode
157 Pancreatic cancer Neoplasms 1.26 0.846 – 1.87 0.257 21 1584 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.07 0.924 – 1.23 0.375 191 2741 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.06 0.992 – 1.13 0.0842 994 13798 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.1 0.766 – 1.59 0.599 27 509 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.2 0.718 – 2.01 0.486 10 485 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.789 0.499 – 1.25 0.313 17 445 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 1.3 0.731 – 2.32 0.371 13 148 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.18 1 – 1.39 0.0456 143 6643 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.24 1.01 – 1.51 0.0358 94 5211 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 0.948 0.748 – 1.2 0.662 71 1101 exclusion phecode
170.1 Bone cancer Neoplasms 1.31 0.812 – 2.11 0.269 19 367 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 0.897 0.68 – 1.18 0.441 54 800 exclusion phecode
172 Skin cancer Neoplasms 0.993 0.958 – 1.03 0.683 3324 33309 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1 0.927 – 1.09 0.904 649 6783 exclusion phecode
172.11 Melanomas of skin Neoplasms 1 0.926 – 1.09 0.938 657 6873 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.994 0.956 – 1.03 0.772 2730 26979 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.962 0.82 – 1.13 0.632 159 1549 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.961 0.705 – 1.31 0.8 43 482 exclusion phecode
174 Breast cancer Neoplasms 1.02 0.977 – 1.05 0.44 2926 32892 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1.01 0.972 – 1.05 0.611 2884 32349 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.01 0.972 – 1.05 0.562 2680 30434 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.35 0.93 – 1.95 0.115 33 296 exclusion phecode
175 Acquired absence of breast Neoplasms 1.06 0.961 – 1.16 0.259 479 6140 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 0.976 0.89 – 1.07 0.601 500 5974 exclusion phecode
180.1 Cervical cancer Neoplasms 0.872 0.654 – 1.16 0.352 52 691 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.983 0.895 – 1.08 0.719 477 5696 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.929 0.819 – 1.05 0.248 265 3167 exclusion phecode
184 Cancer of other female genital organs Neoplasms 0.797 0.695 – 0.915 0.00124 231 3453 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.777 0.653 – 0.923 0.00413 147 2381 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.781 0.654 – 0.932 0.00627 139 2338 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.815 0.624 – 1.06 0.131 62 775 exclusion phecode
185 Cancer of prostate Neoplasms 0.952 0.901 – 1.01 0.08 1388 14781 exclusion phecode
187 Cancer of other male genital organs Neoplasms 1.16 0.958 – 1.41 0.126 114 1090 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.28 0.784 – 2.1 0.323 17 170 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 1.14 0.891 – 1.45 0.3 72 684 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.05 0.709 – 1.57 0.793 28 256 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1 0.928 – 1.08 0.994 740 10347 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.931 0.796 – 1.09 0.365 163 2749 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.955 0.813 – 1.12 0.574 154 2658 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.722 0.416 – 1.26 0.249 12 144 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.03 0.93 – 1.13 0.608 432 5924 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.05 0.943 – 1.16 0.388 380 5280 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.916 0.576 – 1.46 0.71 16 346 exclusion phecode
190 Cancer of eye Neoplasms 0.828 0.569 – 1.2 0.323 31 445 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.817 0.603 – 1.11 0.19 44 1766 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.664 0.449 – 0.983 0.0408 22 1455 exclusion phecode
191.11 Cancer of brain Neoplasms 0.833 0.497 – 1.4 0.49 12 1359 exclusion phecode
193 Thyroid cancer Neoplasms 0.972 0.777 – 1.22 0.806 82 893 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 2.34 1.29 – 4.22 0.00484 13 239 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.03 0.991 – 1.07 0.139 3203 42925 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.02 0.985 – 1.06 0.246 3040 41323 exclusion phecode
197 Chemotherapy Neoplasms 1.02 0.983 – 1.05 0.325 3600 55980 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.03 0.967 – 1.1 0.348 998 24532 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.05 0.977 – 1.13 0.181 782 13976 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.931 0.751 – 1.15 0.51 82 5842 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.03 0.824 – 1.29 0.787 78 3915 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.11 0.893 – 1.37 0.357 82 6845 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.12 0.629 – 2 0.698 7 2215 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 0.895 0.71 – 1.13 0.345 70 5556 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.903 0.567 – 1.44 0.668 14 488 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 0.928 0.813 – 1.06 0.265 228 3676 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.37 0.759 – 2.47 0.297 9 273 exclusion phecode
200 Myeloproliferative disease Neoplasms 0.936 0.8 – 1.1 0.413 164 2455 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.08 0.834 – 1.41 0.544 55 922 exclusion phecode
201 Hodgkin's disease Neoplasms 0.963 0.727 – 1.28 0.793 49 663 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.999 0.907 – 1.1 0.976 445 5644 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.02 0.918 – 1.14 0.687 353 4425 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.08 0.878 – 1.34 0.453 92 900 exclusion phecode
202.24 Large cell lymphoma Neoplasms 0.969 0.792 – 1.18 0.756 101 1401 exclusion phecode
204 Leukemia Neoplasms 0.98 0.866 – 1.11 0.746 261 4161 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1.04 0.858 – 1.26 0.692 107 1426 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.2 0.65 – 2.22 0.556 9 135 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.961 0.781 – 1.18 0.704 93 1248 exclusion phecode
204.2 Myeloid leukemia Neoplasms 0.839 0.64 – 1.1 0.203 52 1157 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.879 0.624 – 1.24 0.458 33 820 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.91 0.623 – 1.33 0.625 24 348 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.1 0.89 – 1.36 0.378 86 1408 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1.06 1.02 – 1.09 0.000634 4210 48661 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.08 0.943 – 1.24 0.264 229 2486 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.936 0.881 – 0.994 0.0321 1162 13195 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.832 0.646 – 1.07 0.154 60 854 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.92 0.727 – 1.17 0.492 73 819 exclusion phecode
214 Lipoma Neoplasms 1.01 0.954 – 1.06 0.821 1466 15816 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.03 0.969 – 1.1 0.335 1073 11800 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.1 0.971 – 1.25 0.132 265 2775 exclusion phecode
216 Benign neoplasm of skin Neoplasms 1.03 0.984 – 1.08 0.198 1946 19924 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.03 0.858 – 1.24 0.745 127 1555 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.989 0.82 – 1.19 0.912 118 1461 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 1.02 0.978 – 1.06 0.383 2651 27371 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 1.02 0.976 – 1.06 0.445 2697 27664 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.957 0.77 – 1.19 0.696 85 979 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.96 0.86 – 1.07 0.469 356 3845 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.754 0.548 – 1.04 0.0847 44 552 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.927 0.653 – 1.32 0.671 42 392 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.798 0.562 – 1.13 0.208 34 418 exclusion phecode
224 Benign neoplasm of eye Neoplasms 1.29 0.824 – 2.01 0.268 21 307 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.52 0.83 – 2.77 0.176 13 143 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.849 0.725 – 0.994 0.0415 165 2047 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.864 0.736 – 1.01 0.0753 158 1940 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.785 0.41 – 1.5 0.466 10 156 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.908 0.705 – 1.17 0.452 63 661 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.897 0.777 – 1.04 0.14 193 2198 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.895 0.642 – 1.25 0.511 35 455 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.953 0.775 – 1.17 0.652 91 934 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.867 0.685 – 1.1 0.235 71 819 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.05 0.948 – 1.17 0.327 380 4076 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.01 0.923 – 1.1 0.854 546 6129 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.958 0.8 – 1.15 0.639 124 1579 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.863 0.756 – 0.985 0.0287 244 2876 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.803 0.656 – 0.982 0.0329 102 1232 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.887 0.75 – 1.05 0.164 151 1725 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.947 0.852 – 1.05 0.321 374 4717 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.816 0.67 – 0.993 0.0419 102 1206 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 0.852 0.562 – 1.29 0.451 24 251 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.783 0.541 – 1.13 0.194 28 342 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 0.969 0.932 – 1.01 0.104 2830 37215 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.907 0.783 – 1.05 0.193 198 2779 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.21 0.748 – 1.95 0.438 18 236 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.971 0.934 – 1.01 0.144 2689 35594 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.853 0.658 – 1.1 0.228 60 755 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.904 0.673 – 1.22 0.504 44 579 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.879 0.654 – 1.18 0.394 43 573 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.07 0.856 – 1.34 0.542 87 1062 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 0.973 0.936 – 1.01 0.157 2758 48126 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.984 0.886 – 1.09 0.769 366 7172 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.27 0.823 – 1.95 0.284 18 593 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.774 0.295 – 2.03 0.601 2 193 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.841 0.659 – 1.07 0.165 65 1248 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 0.946 0.597 – 1.5 0.815 19 419 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.969 0.93 – 1.01 0.127 2400 43882 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.51 0.891 – 2.57 0.125 11 280 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 2.24 1.15 – 4.37 0.0181 9 520 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.08 0.878 – 1.33 0.47 92 2507 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 0.812 0.573 – 1.15 0.241 31 1312 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.01 0.834 – 1.23 0.883 98 1789 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.19 0.89 – 1.58 0.244 45 694 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.902 0.693 – 1.18 0.446 53 1098 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.05 0.683 – 1.62 0.819 20 342 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.12 0.787 – 1.58 0.537 30 928 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.951 0.808 – 1.12 0.549 151 3332 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.13 0.92 – 1.38 0.245 91 2401 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.936 0.806 – 1.09 0.38 182 2189 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.953 0.817 – 1.11 0.537 167 1936 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.93 0.637 – 1.36 0.707 27 386 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.05 0.885 – 1.24 0.584 130 1696 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.918 0.682 – 1.23 0.569 42 497 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.657 0.413 – 1.05 0.0766 18 224 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.931 0.721 – 1.2 0.585 55 642 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.07 0.678 – 1.7 0.766 15 243 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.17 0.761 – 1.8 0.475 21 340 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.09 0.9 – 1.32 0.377 107 1630 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.26 0.884 – 1.78 0.204 28 482 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.01 0.677 – 1.52 0.946 17 256 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.67 0.958 – 2.92 0.0706 12 206 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.08 0.841 – 1.4 0.533 66 918 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.09 0.842 – 1.4 0.527 66 910 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.989 0.781 – 1.25 0.927 78 661 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.09 0.836 – 1.41 0.538 61 580 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1.13 0.814 – 1.58 0.458 36 388 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.17 0.821 – 1.68 0.381 32 373 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.03 0.641 – 1.64 0.915 19 258 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.987 0.703 – 1.38 0.938 31 419 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.823 0.529 – 1.28 0.387 19 482 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.48 0.658 – 3.34 0.342 3 109 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.07 0.884 – 1.3 0.475 110 2030 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.04 0.896 – 1.21 0.587 181 3040 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.2 0.984 – 1.46 0.0716 107 1867 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.85 0.666 – 1.08 0.192 72 1187 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.29 0.682 – 2.43 0.435 12 190 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.935 0.705 – 1.24 0.641 51 591 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.27 0.979 – 1.65 0.0723 58 857 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.869 0.648 – 1.16 0.346 49 741 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.859 0.633 – 1.17 0.329 42 617 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 0.787 0.552 – 1.12 0.187 33 451 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1 0.583 – 1.71 0.999 13 277 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.97 0.555 – 1.7 0.916 9 155 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.789 0.55 – 1.13 0.199 31 416 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.782 0.543 – 1.13 0.188 28 356 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.01 0.987 – 1.04 0.303 6032 61984 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.01 0.987 – 1.04 0.321 6014 61915 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.02 0.992 – 1.05 0.174 5571 59897 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.898 0.517 – 1.56 0.705 11 164 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.1 0.776 – 1.56 0.589 26 425 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.01 0.717 – 1.43 0.952 34 556 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.13 1.04 – 1.23 0.00469 577 9226 exclusion phecode
274.1 Gout Endocrine/metabolic 1.15 1.05 – 1.26 0.00199 482 7841 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.17 0.616 – 2.22 0.634 8 251 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.04 0.855 – 1.25 0.72 106 1560 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.08 0.892 – 1.31 0.426 102 1426 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.933 0.828 – 1.05 0.251 280 5222 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 1.01 0.851 – 1.21 0.87 131 1634 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 0.961 0.646 – 1.43 0.845 23 931 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.873 0.737 – 1.03 0.117 135 3015 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.941 0.594 – 1.49 0.795 15 448 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.05 0.979 – 1.14 0.163 726 18056 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.05 0.947 – 1.16 0.372 402 10103 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.972 0.569 – 1.66 0.918 11 613 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.08 0.932 – 1.25 0.312 187 4566 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.13 0.905 – 1.41 0.28 81 2352 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 0.953 0.81 – 1.12 0.562 153 3536 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.07 0.866 – 1.31 0.544 85 2890 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.05 0.839 – 1.32 0.659 72 2624 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.21 0.671 – 2.17 0.529 12 279 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.02 0.904 – 1.14 0.783 287 7019 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 0.788 0.525 – 1.18 0.251 22 1079 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.62 0.986 – 2.65 0.057 14 323 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.06 0.876 – 1.28 0.556 118 2237 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.989 0.792 – 1.23 0.919 83 931 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.835 0.614 – 1.14 0.251 39 561 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.961 0.478 – 1.93 0.912 8 115 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.995 0.947 – 1.05 0.846 1681 27901 exclusion phecode
278.1 Obesity Endocrine/metabolic 1 0.954 – 1.05 0.92 1652 27504 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 0.683 0.412 – 1.13 0.139 15 236 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.522 0.279 – 0.978 0.0424 13 189 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.16 0.858 – 1.57 0.337 44 656 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.28 0.915 – 1.8 0.148 36 541 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.49 1.02 – 2.19 0.0411 27 371 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.34 1.03 – 1.74 0.0295 63 628 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1 0.952 – 1.06 0.874 1462 19527 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1 0.95 – 1.06 0.876 1384 18733 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.01 0.812 – 1.26 0.931 95 1207 exclusion phecode
281 Other deficiency anemia Hematopoietic 0.979 0.831 – 1.15 0.804 145 2750 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 0.987 0.835 – 1.17 0.883 139 2650 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.05 0.86 – 1.28 0.633 98 1859 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.06 0.756 – 1.49 0.724 30 416 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 0.745 0.47 – 1.18 0.209 16 499 exclusion phecode
281.9 Deficiency anemias Hematopoietic 0.782 0.385 – 1.59 0.496 6 131 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 0.594 0.408 – 0.865 0.00659 31 407 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 0.688 0.408 – 1.16 0.162 14 168 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.777 0.451 – 1.34 0.364 14 195 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.21 0.765 – 1.9 0.419 18 332 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.29 0.765 – 2.16 0.343 13 255 exclusion phecode
284 Aplastic anemia Hematopoietic 0.954 0.716 – 1.27 0.746 45 1069 exclusion phecode
285 Other anemias Hematopoietic 0.956 0.913 – 1 0.0563 1943 30867 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.09 0.823 – 1.45 0.545 51 693 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.21 0.925 – 1.58 0.164 56 1743 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.38 0.955 – 1.99 0.0863 28 1021 exclusion phecode
286 Coagulation defects Hematopoietic 0.996 0.852 – 1.16 0.96 163 2380 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.995 0.824 – 1.2 0.957 111 1218 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.92 0.616 – 1.37 0.685 25 263 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.02 0.807 – 1.28 0.897 68 757 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 0.751 0.455 – 1.24 0.261 15 171 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.855 0.539 – 1.36 0.507 13 205 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.863 0.664 – 1.12 0.269 53 976 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.06 0.934 – 1.21 0.35 237 4182 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.18 0.768 – 1.82 0.448 21 319 exclusion phecode
287.2 Allergic purpura Hematopoietic 0.804 0.36 – 1.8 0.594 8 132 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.05 0.921 – 1.21 0.445 221 3945 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.13 0.91 – 1.4 0.268 83 1072 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.83 0.826 – 4.04 0.137 7 181 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.02 0.932 – 1.11 0.722 546 9599 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.01 0.921 – 1.11 0.784 446 8100 exclusion phecode
288.11 Neutropenia Hematopoietic 1.01 0.921 – 1.11 0.787 447 8119 exclusion phecode
288.3 Eosinophilia Hematopoietic 1.16 0.73 – 1.85 0.525 15 182 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.15 0.975 – 1.34 0.0978 160 2225 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.2 0.907 – 1.59 0.2 51 805 exclusion phecode
289.4 Lymphadenitis Hematopoietic 0.962 0.871 – 1.06 0.45 409 6611 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1.1 0.855 – 1.4 0.472 67 1269 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 0.791 0.589 – 1.06 0.119 41 710 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.42 0.865 – 2.32 0.167 14 240 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.23 1.01 – 1.51 0.0437 89 4335 exclusion phecode
290.1 Dementias Mental Disorders 1.25 0.891 – 1.75 0.197 30 2229 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 1.87 1.01 – 3.47 0.0456 7 957 exclusion phecode
290.16 Vascular dementia Mental Disorders 1.61 0.79 – 3.28 0.19 5 442 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.49 1.09 – 2.04 0.012 37 1510 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.838 0.399 – 1.76 0.639 7 158 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.885 0.727 – 1.08 0.222 101 2020 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.763 0.504 – 1.16 0.202 20 320 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.793 0.527 – 1.2 0.269 20 670 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 0.947 0.733 – 1.22 0.676 61 1066 exclusion phecode
292 Neurological disorders Mental Disorders 1.04 0.952 – 1.13 0.387 535 11443 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.2 1.03 – 1.38 0.0167 188 3793 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.542 0.316 – 0.929 0.0258 12 442 exclusion phecode
292.3 Memory loss Mental Disorders 1.01 0.845 – 1.21 0.907 129 1786 exclusion phecode
292.4 Altered mental status Mental Disorders 0.976 0.848 – 1.12 0.739 204 5358 exclusion phecode
292.6 Hallucinations Mental Disorders 1.29 0.899 – 1.86 0.167 26 739 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.02 0.931 – 1.13 0.623 451 5311 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.04 0.885 – 1.23 0.614 153 2267 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.27 0.994 – 1.61 0.0556 62 2187 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.08 0.802 – 1.46 0.608 40 1457 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.67 0.939 – 2.97 0.0811 11 455 exclusion phecode
295.3 Psychosis Mental Disorders 1.64 1.04 – 2.58 0.0317 19 473 exclusion phecode
296 Mood disorders Mental Disorders 0.939 0.895 – 0.987 0.0122 1702 33167 exclusion phecode
296.1 Bipolar Mental Disorders 0.876 0.731 – 1.05 0.149 116 2810 exclusion phecode
296.2 Depression Mental Disorders 0.945 0.898 – 0.993 0.0258 1619 31422 exclusion phecode
296.22 Major depressive disorder Mental Disorders 0.856 0.626 – 1.17 0.328 38 970 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.968 0.689 – 1.36 0.85 31 756 exclusion phecode
300 Anxiety disorders Mental Disorders 0.995 0.933 – 1.06 0.868 978 18102 exclusion phecode
300.1 Anxiety disorder Mental Disorders 0.979 0.916 – 1.05 0.525 909 16771 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 0.951 0.643 – 1.41 0.8 22 410 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.04 0.852 – 1.28 0.687 96 1812 exclusion phecode
300.13 Phobia Mental Disorders 0.918 0.745 – 1.13 0.418 90 1290 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.84 0.525 – 1.34 0.465 16 370 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.05 0.557 – 1.97 0.885 10 154 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.63 0.938 – 2.84 0.0829 13 320 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.831 0.492 – 1.41 0.491 12 306 exclusion phecode
301 Personality disorders Mental Disorders 1.12 0.774 – 1.62 0.548 26 888 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.887 0.505 – 1.56 0.676 11 306 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 1.04 0.788 – 1.38 0.764 50 743 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.978 0.792 – 1.21 0.835 87 1268 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.904 0.715 – 1.14 0.402 71 947 exclusion phecode
303.4 Somatoform disorder Mental Disorders 1.12 0.694 – 1.8 0.646 17 312 exclusion phecode
304 Adjustment reaction Mental Disorders 1.17 0.865 – 1.59 0.302 40 782 exclusion phecode
305.2 Eating disorder Mental Disorders 0.765 0.468 – 1.25 0.285 14 276 exclusion phecode
306 Other mental disorder Mental Disorders 1.09 1.06 – 1.12 3.72e-08 4746 60687 exclusion phecode
306.9 Tension headache Mental Disorders 0.881 0.661 – 1.18 0.39 45 823 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.734 0.405 – 1.33 0.308 8 213 exclusion phecode
313.3 Autism Mental Disorders 0.377 0.145 – 0.98 0.0454 5 142 exclusion phecode
315 Develomental delays and disorders Mental Disorders 0.954 0.64 – 1.42 0.818 19 891 exclusion phecode
315.1 Learning disorder Mental Disorders 1.3 0.534 – 3.15 0.565 2 407 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.807 0.39 – 1.67 0.563 5 228 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.32 1.19 – 1.46 1.79e-07 374 13669 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.55 0.787 – 3.05 0.205 8 171 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.22 1.16 – 1.28 5.56e-16 1799 33088 exclusion phecode
317.1 Alcoholism Mental Disorders 1.21 1.15 – 1.28 2.46e-12 1442 23249 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.43 1.01 – 2.01 0.0439 30 2220 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.15 1.1 – 1.2 2.63e-10 2262 48409 exclusion phecode
320 Meningitis Neurological 0.974 0.791 – 1.2 0.805 94 1196 exclusion phecode
323 Encephalitis Neurological 0.802 0.614 – 1.05 0.105 63 870 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 0.731 0.477 – 1.12 0.149 24 196 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 0.94 0.712 – 1.24 0.663 48 712 exclusion phecode
327 Sleep disorders Neurological 1.04 0.915 – 1.18 0.568 250 2968 exclusion phecode
327.3 Sleep apnea Neurological 0.961 0.896 – 1.03 0.255 861 11373 exclusion phecode
327.4 Insomnia Neurological 0.949 0.649 – 1.39 0.786 28 410 exclusion phecode
327.41 Organic or persistent insomnia Neurological 0.945 0.621 – 1.44 0.791 24 345 exclusion phecode
331 Other cerebral degenerations Neurological 1.01 0.815 – 1.25 0.937 87 2876 exclusion phecode
331.1 Hydrocephalus Neurological 0.929 0.707 – 1.22 0.596 57 1264 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.43 0.917 – 2.24 0.114 16 1098 exclusion phecode
332 Parkinson's disease Neurological 1.17 0.974 – 1.41 0.0928 112 2828 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.13 0.949 – 1.35 0.168 127 2261 exclusion phecode
333.1 Essential tremor Neurological 1.12 0.779 – 1.6 0.544 28 516 exclusion phecode
333.2 Myoclonus Neurological 1.39 0.83 – 2.34 0.209 13 241 exclusion phecode
333.4 Torsion dystonia Neurological 1.41 1.04 – 1.91 0.028 46 652 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.09 0.953 – 1.24 0.215 231 4553 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.06 0.671 – 1.66 0.816 15 291 exclusion phecode
334.2 Anterior horn cell disease Neurological 1.03 0.635 – 1.66 0.91 11 599 exclusion phecode
335 Multiple sclerosis Neurological 0.967 0.857 – 1.09 0.593 277 3617 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.13 0.842 – 1.51 0.422 40 673 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 0.991 0.595 – 1.65 0.973 11 177 exclusion phecode
338 Pain Neurological 1.03 0.856 – 1.24 0.758 119 2052 exclusion phecode
338.1 Acute pain Neurological 1.02 0.801 – 1.31 0.846 63 1039 exclusion phecode
338.2 Chronic pain Neurological 1.04 0.795 – 1.37 0.762 57 1019 exclusion phecode
339 Other headache syndromes Neurological 0.986 0.933 – 1.04 0.63 1321 20176 exclusion phecode
340 Migraine Neurological 0.918 0.843 – 1 0.05 564 7551 exclusion phecode
340.1 Migrain with aura Neurological 1.19 0.885 – 1.6 0.25 45 568 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.03 0.783 – 1.35 0.847 48 703 exclusion phecode
342 Hemiplegia Neurological 1.01 0.856 – 1.19 0.903 145 3801 exclusion phecode
343 Infantile cerebral palsy Neurological 1.21 0.787 – 1.87 0.383 21 400 exclusion phecode
344 Other paralytic syndromes Neurological 1.07 0.879 – 1.31 0.481 103 1690 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.92 0.85 – 0.996 0.0388 641 12673 exclusion phecode
345.1 Epilepsy Neurological 0.938 0.765 – 1.15 0.539 93 2222 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 0.845 0.617 – 1.16 0.293 39 1109 exclusion phecode
345.12 Partial epilepsy Neurological 0.861 0.631 – 1.18 0.347 37 671 exclusion phecode
345.3 Convulsions Neurological 0.985 0.863 – 1.13 0.828 225 5620 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.06 0.637 – 1.76 0.829 14 363 exclusion phecode
348 Other conditions of brain Neurological 1.05 0.839 – 1.32 0.668 77 2104 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1 0.681 – 1.48 0.989 23 733 exclusion phecode
348.4 Cerebral cysts Neurological 0.784 0.518 – 1.19 0.252 25 369 exclusion phecode
348.7 Coma Neurological 1.05 0.797 – 1.39 0.713 48 853 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.6 1.1 – 2.32 0.0137 25 638 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.25 0.905 – 1.73 0.174 36 1018 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.753 0.558 – 1.02 0.063 44 878 exclusion phecode
350 Abnormal movement Neurological 0.968 0.86 – 1.09 0.592 295 6552 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.11 0.927 – 1.34 0.249 118 2186 exclusion phecode
350.2 Abnormality of gait Neurological 0.869 0.734 – 1.03 0.101 140 3851 exclusion phecode
350.3 Lack of coordination Neurological 0.868 0.668 – 1.13 0.291 55 909 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.521 0.231 – 1.17 0.115 7 149 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.02 0.98 – 1.06 0.31 2469 32386 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.01 0.89 – 1.16 0.83 242 3503 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.14 0.912 – 1.44 0.246 78 1169 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 0.978 0.832 – 1.15 0.784 158 2253 exclusion phecode
353 Nerve root and plexus disorders Neurological 0.998 0.864 – 1.15 0.979 203 2857 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.83 0.554 – 1.24 0.365 24 329 exclusion phecode
353.2 Nerve root lesions Neurological 0.827 0.436 – 1.57 0.561 8 134 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.739 0.522 – 1.04 0.087 32 387 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 0.886 0.776 – 1.01 0.0752 221 3417 exclusion phecode
358 Myoneural disorders Neurological 0.796 0.576 – 1.1 0.167 31 515 exclusion phecode
358.1 Myasthenia gravis Neurological 0.738 0.529 – 1.03 0.0738 29 464 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.915 0.728 – 1.15 0.448 73 1188 exclusion phecode
359.1 Muscular dystrophies Neurological 0.753 0.476 – 1.19 0.225 19 305 exclusion phecode
359.2 Myopathy Neurological 0.926 0.712 – 1.2 0.565 56 924 exclusion phecode
360 Disorders of the globe Sense Organs 1.05 0.852 – 1.3 0.632 98 878 exclusion phecode
360.2 Progressive myopia Sense Organs 1.08 0.854 – 1.38 0.507 78 658 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.976 0.914 – 1.04 0.482 978 8452 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.964 0.871 – 1.07 0.48 421 3720 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 1.18 0.745 – 1.87 0.481 20 168 exclusion phecode
362 Other retinal disorders Sense Organs 1.05 0.975 – 1.13 0.199 782 9252 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.07 0.968 – 1.18 0.193 447 5133 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.07 0.971 – 1.18 0.172 445 5132 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.935 0.688 – 1.27 0.665 47 394 exclusion phecode
362.31 Separation of retinal layers Sense Organs 0.969 0.641 – 1.46 0.881 27 226 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.868 0.737 – 1.02 0.092 150 2032 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 1.22 0.929 – 1.6 0.154 54 497 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.19 0.731 – 1.94 0.483 16 208 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.26 0.83 – 1.93 0.275 23 300 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.03 0.767 – 1.39 0.84 48 419 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.885 0.541 – 1.45 0.627 18 176 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.14 0.962 – 1.36 0.129 141 1559 exclusion phecode
364.1 Corneal opacity Sense Organs 2.15 1.16 – 4 0.0155 13 225 exclusion phecode
364.2 Corneal edema Sense Organs 0.97 0.538 – 1.75 0.92 14 196 exclusion phecode
364.4 Corneal degenerations Sense Organs 1.26 0.93 – 1.69 0.138 43 468 exclusion phecode
364.41 Keratoconus Sense Organs 1.16 0.739 – 1.82 0.52 22 217 exclusion phecode
364.5 Corneal dystrophy Sense Organs 1.13 0.826 – 1.54 0.45 42 502 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.962 0.647 – 1.43 0.847 23 251 exclusion phecode
365 Glaucoma Sense Organs 1.03 0.959 – 1.1 0.459 937 10695 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 0.942 0.821 – 1.08 0.389 225 2541 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.921 0.802 – 1.06 0.241 223 2537 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.09 0.915 – 1.3 0.336 133 1660 exclusion phecode
366 Cataract Sense Organs 1.05 1.01 – 1.08 0.00621 4187 42000 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.875 0.518 – 1.48 0.616 11 177 exclusion phecode
366.2 Senile cataract Sense Organs 1.05 1 – 1.11 0.0522 1640 19278 exclusion phecode
366.3 Traumatic cataract Sense Organs 1.21 0.744 – 1.97 0.442 19 213 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.964 0.884 – 1.05 0.401 565 6073 exclusion phecode
367.1 Myopia Sense Organs 1.04 0.936 – 1.16 0.447 368 3204 exclusion phecode
367.2 Astigmatism Sense Organs 0.979 0.701 – 1.37 0.903 38 471 exclusion phecode
367.8 Hypermetropia Sense Organs 0.732 0.562 – 0.952 0.0201 59 590 exclusion phecode
367.9 Blindness and low vision Sense Organs 0.861 0.699 – 1.06 0.158 90 1796 exclusion phecode
368 Visual disturbances Sense Organs 0.94 0.861 – 1.03 0.172 545 7351 exclusion phecode
368.1 Amblyopia Sense Organs 1.02 0.834 – 1.24 0.869 107 1187 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.871 0.74 – 1.03 0.0968 154 1857 exclusion phecode
368.3 Anisometropia Sense Organs 0.936 0.693 – 1.26 0.667 45 374 exclusion phecode
368.4 Visual field defects Sense Organs 0.833 0.637 – 1.09 0.184 53 895 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 1.22 0.978 – 1.52 0.0782 84 1572 exclusion phecode
369 Infection of the eye Sense Organs 1.16 0.949 – 1.41 0.149 111 1426 exclusion phecode
369.2 Eye infection, viral Sense Organs 1.45 0.962 – 2.18 0.0762 25 325 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 1.14 0.792 – 1.63 0.486 33 551 exclusion phecode
370 Keratitis Sense Organs 1.02 0.767 – 1.35 0.907 55 700 exclusion phecode
370.1 Corneal ulcer Sense Organs 1.22 0.837 – 1.79 0.297 29 335 exclusion phecode
371 Inflammation of the eye Sense Organs 0.966 0.894 – 1.04 0.372 704 7780 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.934 0.769 – 1.13 0.487 107 1274 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.932 0.855 – 1.02 0.111 551 5932 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.01 0.855 – 1.18 0.935 146 1900 exclusion phecode
374 Other disorders of eyelids Sense Organs 1.01 0.95 – 1.07 0.799 1213 14169 exclusion phecode
374.1 Ectropion or entropion Sense Organs 1.03 0.893 – 1.19 0.671 201 2573 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.972 0.877 – 1.08 0.597 389 4467 exclusion phecode
375 Disorders of lacrimal system Sense Organs 1.08 0.982 – 1.18 0.113 478 5322 exclusion phecode
375.2 Epiphora Sense Organs 1.23 1.06 – 1.43 0.00649 194 2145 exclusion phecode
376 Disorders of the orbit Sense Organs 0.995 0.601 – 1.65 0.984 13 249 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.945 0.74 – 1.21 0.651 65 921 exclusion phecode
377.1 Optic atrophy Sense Organs 1.49 0.818 – 2.7 0.193 11 141 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.883 0.586 – 1.33 0.554 21 326 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.983 0.873 – 1.11 0.77 288 3588 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.1 0.957 – 1.27 0.177 212 2312 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.733 0.543 – 0.989 0.042 43 550 exclusion phecode
378.5 Paralytic strabismus Sense Organs 0.868 0.631 – 1.19 0.384 35 707 exclusion phecode
379 Other disorders of eye Sense Organs 1.01 0.935 – 1.08 0.892 813 8986 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.99 0.883 – 1.11 0.857 340 3446 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.02 0.911 – 1.13 0.775 359 4189 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 0.962 0.592 – 1.56 0.877 15 190 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.927 0.738 – 1.17 0.519 83 1023 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.789 0.539 – 1.15 0.222 26 436 exclusion phecode
380 Disorders of external ear Sense Organs 1.09 0.912 – 1.29 0.354 138 1556 exclusion phecode
380.1 Otitis externa Sense Organs 1.09 0.888 – 1.34 0.406 102 1248 exclusion phecode
380.4 Impacted cerumen Sense Organs 1.07 0.858 – 1.34 0.53 80 951 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.04 0.938 – 1.15 0.48 410 5331 exclusion phecode
381.1 Otitis media Sense Organs 1.07 0.96 – 1.2 0.212 331 4330 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.06 0.897 – 1.26 0.481 141 2138 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.875 0.633 – 1.21 0.418 38 496 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.853 0.594 – 1.22 0.389 32 414 exclusion phecode
381.9 Otorrhea Sense Organs 1.04 0.804 – 1.36 0.744 55 726 exclusion phecode
382 Otalgia Sense Organs 1.21 0.95 – 1.55 0.121 69 784 exclusion phecode
383 Otosclerosis Sense Organs 1.04 0.845 – 1.27 0.725 94 749 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 0.973 0.856 – 1.11 0.673 237 3348 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.03 0.888 – 1.19 0.702 179 2640 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.913 0.78 – 1.07 0.259 159 2033 exclusion phecode
385.3 Cholesteatoma Sense Organs 0.85 0.713 – 1.01 0.0697 126 1589 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.18 0.856 – 1.62 0.316 34 596 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1 0.902 – 1.12 0.931 352 4420 exclusion phecode
386.1 Meniere's disease Sense Organs 1.06 0.889 – 1.28 0.496 126 1465 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.983 0.781 – 1.24 0.882 72 944 exclusion phecode
386.3 Labyrinthitis Sense Organs 0.926 0.784 – 1.09 0.367 144 1966 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.01 0.939 – 1.09 0.787 775 11412 exclusion phecode
388 Other disorders of ear Sense Organs 0.908 0.656 – 1.26 0.562 34 489 exclusion phecode
389 Hearing loss Sense Organs 1 0.934 – 1.08 0.924 829 10404 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 1.1 0.885 – 1.36 0.401 88 1160 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.04 0.858 – 1.26 0.694 109 1170 exclusion phecode
389.4 Tinnitus Sense Organs 1.07 0.876 – 1.31 0.497 106 1291 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.06 0.986 – 1.14 0.114 837 11851 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.07 0.981 – 1.17 0.129 548 7204 exclusion phecode
394.3 Aortic valve disease Circulatory System 0.966 0.839 – 1.11 0.624 208 3087 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.15 0.976 – 1.36 0.0944 150 2551 exclusion phecode
395 Heart valve disorders Circulatory System 1.03 0.96 – 1.12 0.373 728 10153 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.09 0.997 – 1.19 0.0589 525 6968 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.913 0.66 – 1.26 0.584 37 647 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.03 0.66 – 1.6 0.902 18 264 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.32 0.784 – 2.23 0.295 11 215 exclusion phecode
395.6 Heart valve replaced Circulatory System 0.906 0.794 – 1.03 0.144 235 3630 exclusion phecode
396 Abnormal heart sounds Circulatory System 0.86 0.745 – 0.992 0.0388 207 2592 exclusion phecode
401 Hypertension Circulatory System 1.02 1 – 1.04 0.0249 13018 73723 exclusion phecode
401.1 Essential hypertension Circulatory System 1.02 1 – 1.04 0.0233 12994 73671 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 0.94 0.815 – 1.09 0.402 197 4977 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 0.831 0.574 – 1.2 0.327 28 945 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.938 0.803 – 1.1 0.417 170 4069 exclusion phecode
401.3 Other hypertensive complications Circulatory System 0.969 0.601 – 1.56 0.898 17 381 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.01 0.897 – 1.15 0.815 263 4064 exclusion phecode
411 Ischemic Heart Disease Circulatory System 0.995 0.967 – 1.02 0.726 5135 54675 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.01 0.936 – 1.08 0.879 787 13216 exclusion phecode
411.2 Myocardial infarction Circulatory System 1 0.957 – 1.05 0.873 1807 29110 exclusion phecode
411.3 Angina pectoris Circulatory System 1.01 0.971 – 1.05 0.587 2406 36889 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 0.995 0.961 – 1.03 0.772 3489 40271 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.18 1.01 – 1.39 0.0355 166 1779 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.01 0.962 – 1.05 0.801 2047 33936 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.92 0.791 – 1.07 0.279 170 3116 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 0.988 0.871 – 1.12 0.848 246 4591 exclusion phecode
414.2 ASCVD Circulatory System 0.923 0.455 – 1.87 0.823 5 209 exclusion phecode
415 Pulmonary heart disease Circulatory System 0.94 0.867 – 1.02 0.135 617 11178 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.849 0.471 – 1.53 0.587 13 181 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.914 0.721 – 1.16 0.458 67 1447 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 0.849 0.662 – 1.09 0.195 59 1065 exclusion phecode
416 Cardiomegaly Circulatory System 1.01 0.912 – 1.12 0.815 365 6542 exclusion phecode
418 Nonspecific chest pain Circulatory System 0.986 0.958 – 1.01 0.331 5138 70197 exclusion phecode
418.1 Precordial pain Circulatory System 1.01 0.929 – 1.09 0.86 615 9180 exclusion phecode
420 Carditis Circulatory System 1.03 0.928 – 1.15 0.564 359 5274 exclusion phecode
420.1 Myocarditis Circulatory System 1.27 0.868 – 1.85 0.22 26 305 exclusion phecode
420.2 Pericarditis Circulatory System 1.07 0.934 – 1.22 0.334 217 3382 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.62 1.18 – 2.23 0.00296 41 563 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.29 0.747 – 2.24 0.358 12 270 exclusion phecode
420.3 Endocarditis Circulatory System 0.876 0.733 – 1.05 0.146 130 1781 exclusion phecode
425 Cardiomyopathy Circulatory System 1.11 0.969 – 1.26 0.134 229 3173 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.11 0.975 – 1.27 0.114 225 3077 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.937 0.659 – 1.33 0.715 29 328 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.724 0.532 – 0.984 0.039 36 405 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 0.966 0.388 – 2.41 0.941 4 144 exclusion phecode
426 Cardiac conduction disorders Circulatory System 0.989 0.933 – 1.05 0.711 1208 17059 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.1 0.987 – 1.22 0.0855 375 5200 exclusion phecode
426.21 First degree AV block Circulatory System 1.03 0.885 – 1.2 0.699 174 2449 exclusion phecode
426.23 Second degree AV block Circulatory System 1.19 0.972 – 1.47 0.0915 94 1103 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1.11 0.91 – 1.36 0.3 106 1415 exclusion phecode
426.25 Other heart block Circulatory System 1.05 0.689 – 1.59 0.835 21 295 exclusion phecode
426.3 Bundle branch block Circulatory System 0.954 0.877 – 1.04 0.271 573 8101 exclusion phecode
426.31 Right bundle branch block Circulatory System 0.948 0.839 – 1.07 0.385 266 3641 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.03 0.91 – 1.16 0.685 290 4243 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.987 0.761 – 1.28 0.92 58 673 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.27 0.651 – 2.48 0.483 8 133 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.02 0.916 – 1.13 0.756 373 6088 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.02 0.913 – 1.13 0.753 344 5577 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.02 0.993 – 1.06 0.128 4365 52962 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.03 0.949 – 1.12 0.466 607 8203 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.03 0.942 – 1.14 0.48 472 6026 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.982 0.832 – 1.16 0.829 147 2371 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.05 1 – 1.09 0.031 2560 33529 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.01 0.932 – 1.1 0.769 614 8184 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.19 1 – 1.42 0.0502 132 3049 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.28 0.993 – 1.65 0.0563 69 916 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.14 0.928 – 1.41 0.209 90 2510 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.08 0.92 – 1.26 0.352 178 2360 exclusion phecode
427.6 Premature beats Circulatory System 1.05 0.871 – 1.27 0.604 116 1405 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1.71 1.13 – 2.57 0.0105 23 314 exclusion phecode
427.7 Tachycardia NOS Circulatory System 0.941 0.834 – 1.06 0.324 274 5557 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.4 1.11 – 1.76 0.00456 79 993 exclusion phecode
427.9 Palpitations Circulatory System 1.02 0.943 – 1.09 0.688 791 9698 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.05 0.97 – 1.15 0.211 563 13485 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 0.899 0.77 – 1.05 0.18 162 5071 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.09 0.992 – 1.19 0.0736 461 10646 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.07 0.907 – 1.27 0.409 144 1835 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 0.5 0.245 – 1.02 0.0575 11 160 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.12 0.914 – 1.37 0.277 104 1333 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 0.961 0.704 – 1.31 0.802 40 511 exclusion phecode
430 Intracranial hemorrhage Circulatory System 0.885 0.781 – 1 0.0553 268 4716 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.921 0.781 – 1.09 0.33 152 2136 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 0.81 0.65 – 1.01 0.0613 77 1877 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 0.907 0.656 – 1.25 0.553 37 626 exclusion phecode
433 Cerebrovascular disease Circulatory System 0.982 0.926 – 1.04 0.545 1172 21552 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.11 0.931 – 1.32 0.246 130 2816 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.38 0.883 – 2.17 0.157 19 547 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.01 0.919 – 1.1 0.912 508 10312 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1 0.864 – 1.16 0.999 182 4145 exclusion phecode
433.3 Cerebral ischemia Circulatory System 0.957 0.866 – 1.06 0.394 406 7118 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 0.941 0.843 – 1.05 0.271 335 5282 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 0.983 0.75 – 1.29 0.9 53 1039 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.96 0.793 – 1.16 0.681 103 3276 exclusion phecode
440 Atherosclerosis Circulatory System 1.01 0.862 – 1.18 0.906 161 3232 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.06 0.586 – 1.91 0.852 9 280 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.984 0.8 – 1.21 0.881 93 1851 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 0.861 0.623 – 1.19 0.363 36 667 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 0.943 0.755 – 1.18 0.605 83 1480 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.02 0.724 – 1.43 0.915 34 716 exclusion phecode
442 Other aneurysm Circulatory System 0.905 0.809 – 1.01 0.0783 324 4600 exclusion phecode
442.1 Aortic aneurysm Circulatory System 0.867 0.761 – 0.987 0.0308 234 3517 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.822 0.701 – 0.964 0.0157 154 2145 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.19 0.762 – 1.85 0.448 20 229 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.15 0.825 – 1.59 0.418 39 401 exclusion phecode
442.4 Arterial dissection Circulatory System 0.835 0.515 – 1.35 0.464 14 148 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.06 0.762 – 1.46 0.741 37 522 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.02 0.928 – 1.11 0.733 495 9540 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 0.927 0.812 – 1.06 0.26 228 2937 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.854 0.582 – 1.25 0.42 23 965 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.03 0.937 – 1.13 0.571 481 8895 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.12 0.993 – 1.27 0.0653 259 6058 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.21 0.993 – 1.47 0.0581 98 2236 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.24 0.961 – 1.61 0.0982 58 1326 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.04 0.882 – 1.23 0.626 147 1991 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 1.11 0.844 – 1.47 0.451 44 492 exclusion phecode
446.5 Giant cell arteritis Circulatory System 0.928 0.708 – 1.21 0.586 57 920 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.37 1.02 – 1.85 0.0394 46 580 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.14 0.983 – 1.33 0.0814 173 3243 exclusion phecode
447.1 Stricture of artery Circulatory System 1.21 0.977 – 1.49 0.0807 90 2082 exclusion phecode
448 Disease of capillaries Circulatory System 1.33 0.868 – 2.05 0.188 25 349 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.05 0.865 – 1.27 0.633 103 1795 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.04 0.962 – 1.12 0.337 677 10181 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.04 0.965 – 1.13 0.286 632 9446 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 0.939 0.749 – 1.18 0.588 75 1465 exclusion phecode
454 Varicose veins Circulatory System 1.04 0.994 – 1.08 0.0939 2436 29007 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1.03 0.993 – 1.08 0.102 2512 29718 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.17 0.972 – 1.41 0.0962 118 1572 exclusion phecode
455 Hemorrhoids Circulatory System 1.01 0.983 – 1.04 0.44 5193 60512 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.886 0.596 – 1.32 0.547 27 468 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.983 0.68 – 1.42 0.928 34 231 exclusion phecode
458 Hypotension Circulatory System 0.927 0.865 – 0.993 0.0314 859 14581 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 0.962 0.81 – 1.14 0.661 134 3265 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 0.982 0.714 – 1.35 0.91 35 592 exclusion phecode
458.9 Hypotension NOS Circulatory System 0.928 0.851 – 1.01 0.0937 550 8817 exclusion phecode
459 Other disorders of circulatory system Circulatory System 0.992 0.953 – 1.03 0.712 2523 40694 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.51 0.894 – 2.54 0.123 15 322 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 0.99 0.951 – 1.03 0.634 2512 40368 exclusion phecode
464 Acute sinusitis Respiratory 1.05 0.767 – 1.44 0.761 40 472 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.971 0.88 – 1.07 0.56 424 5899 exclusion phecode
465.2 Acute pharyngitis Respiratory 1.04 0.886 – 1.21 0.662 166 2181 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.916 0.63 – 1.33 0.644 26 405 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.04 0.976 – 1.11 0.221 1012 11988 exclusion phecode
471 Nasal polyps Respiratory 1.05 0.979 – 1.13 0.163 779 8146 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.02 0.887 – 1.17 0.803 210 2436 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.03 0.935 – 1.13 0.561 432 6303 exclusion phecode
473.1 Chronic laryngitis Respiratory 0.884 0.569 – 1.37 0.582 18 266 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.932 0.68 – 1.28 0.663 37 662 exclusion phecode
473.4 Voice disturbance Respiratory 1.01 0.876 – 1.16 0.896 201 2594 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 0.927 0.833 – 1.03 0.161 370 4514 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.03 0.836 – 1.27 0.773 89 1432 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.946 0.834 – 1.07 0.386 262 2890 exclusion phecode
475 Chronic sinusitis Respiratory 1.03 0.946 – 1.12 0.493 566 6725 exclusion phecode
476 Allergic rhinitis Respiratory 1.06 0.929 – 1.2 0.407 275 2818 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.04 0.941 – 1.15 0.456 425 6067 exclusion phecode
478 Throat pain Respiratory 1.13 0.898 – 1.42 0.295 75 988 exclusion phecode
479 Other upper respiratory disease Respiratory 1.03 0.956 – 1.1 0.475 830 10277 exclusion phecode
480 Pneumonia Respiratory 0.985 0.931 – 1.04 0.605 1272 25655 exclusion phecode
480.1 Bacterial pneumonia Respiratory 0.992 0.926 – 1.06 0.82 853 16506 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 0.999 0.928 – 1.08 0.985 749 14643 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 0.819 0.381 – 1.76 0.609 5 246 exclusion phecode
480.2 Viral pneumonia Respiratory 0.891 0.533 – 1.49 0.66 14 191 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.06 0.607 – 1.86 0.831 11 221 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.25 0.902 – 1.74 0.18 33 1959 exclusion phecode
481 Influenza Respiratory 1.24 0.934 – 1.65 0.137 51 889 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.943 0.674 – 1.32 0.73 36 503 exclusion phecode
495 Asthma Respiratory 1.01 0.985 – 1.04 0.374 5240 65472 exclusion phecode
495.2 Asthma with exacerbation Respiratory 0.997 0.695 – 1.43 0.986 33 659 exclusion phecode
496 Chronic airway obstruction Respiratory 1.07 1 – 1.13 0.0367 1148 25096 exclusion phecode
496.1 Emphysema Respiratory 1.05 0.896 – 1.23 0.536 156 4213 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.1 0.949 – 1.27 0.213 183 7090 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.12 0.961 – 1.31 0.145 158 6473 exclusion phecode
496.3 Bronchiectasis Respiratory 1.05 0.94 – 1.18 0.377 322 4580 exclusion phecode
497 Bronchitis Respiratory 0.897 0.731 – 1.1 0.297 90 1554 exclusion phecode
500 Lung disease due to external agents Respiratory 1 0.694 – 1.44 0.998 28 943 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.03 0.491 – 2.15 0.942 7 185 exclusion phecode
500.2 Pneumoconiosis Respiratory 0.834 0.501 – 1.39 0.487 13 531 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 0.983 0.667 – 1.45 0.93 23 1654 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.03 0.828 – 1.28 0.783 80 2236 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 0.902 0.685 – 1.19 0.462 49 1229 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.09 0.774 – 1.54 0.62 31 804 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.47 0.811 – 2.65 0.205 10 163 exclusion phecode
506 Empyema and pneumothorax Respiratory 0.95 0.818 – 1.1 0.502 177 2879 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.01 0.937 – 1.08 0.839 751 15842 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.03 0.915 – 1.17 0.591 263 5027 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.946 0.814 – 1.1 0.464 175 6488 exclusion phecode
509.1 Respiratory failure Respiratory 1.07 0.887 – 1.28 0.498 116 5174 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.11 0.911 – 1.35 0.303 102 4515 exclusion phecode
509.5 Respiratory arrest Respiratory 0.871 0.519 – 1.46 0.6 11 356 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.728 0.549 – 0.966 0.0279 48 957 exclusion phecode
510 Other diseases of lung Respiratory 1.03 0.837 – 1.26 0.794 95 1836 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.03 0.978 – 1.09 0.251 1404 22647 exclusion phecode
512.1 Wheezing Respiratory 1.16 0.795 – 1.68 0.447 26 554 exclusion phecode
512.2 Painful respiration Respiratory 0.898 0.64 – 1.26 0.534 35 515 exclusion phecode
512.7 Shortness of breath Respiratory 1.04 0.972 – 1.12 0.239 834 14566 exclusion phecode
512.8 Cough Respiratory 1.04 0.946 – 1.14 0.43 483 7242 exclusion phecode
512.9 Other dyspnea Respiratory 0.984 0.834 – 1.16 0.85 146 2185 exclusion phecode
513 Respiratory abnormalities Respiratory 0.97 0.786 – 1.2 0.776 92 1495 exclusion phecode
513.3 Hypoventilation Respiratory 1.08 0.616 – 1.9 0.783 11 209 exclusion phecode
513.4 Hyperventilation Respiratory 0.918 0.665 – 1.27 0.602 39 716 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.15 0.789 – 1.69 0.461 24 416 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 0.957 0.854 – 1.07 0.444 304 5987 exclusion phecode
516 Abnormal sputum Respiratory 1.08 0.96 – 1.22 0.195 274 5164 exclusion phecode
516.1 Hemoptysis Respiratory 1.06 0.94 – 1.2 0.339 271 5021 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.967 0.913 – 1.02 0.247 1246 23357 exclusion phecode
519.2 Respiratory complications Respiratory 0.93 0.665 – 1.3 0.669 33 832 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.971 0.915 – 1.03 0.332 1162 22004 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.779 0.595 – 1.02 0.0702 51 773 exclusion phecode
520 Disorders of tooth development Digestive 0.959 0.876 – 1.05 0.362 522 5331 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.15 0.647 – 2.05 0.63 14 130 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.957 0.88 – 1.04 0.304 602 6111 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 0.973 0.897 – 1.06 0.515 622 7983 exclusion phecode
521.1 Dental caries Digestive 0.98 0.903 – 1.06 0.626 621 7988 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 0.996 0.901 – 1.1 0.942 411 4647 exclusion phecode
522.5 Periapical abscess Digestive 1.06 0.939 – 1.2 0.347 266 3088 exclusion phecode
523 Gingival and periodontal diseases Digestive 0.911 0.819 – 1.01 0.0845 379 4424 exclusion phecode
523.1 Gingivitis Digestive 0.927 0.633 – 1.36 0.694 24 290 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 0.926 0.82 – 1.05 0.222 281 3118 exclusion phecode
523.31 Acute periodontitis Digestive 0.927 0.786 – 1.09 0.363 153 1807 exclusion phecode
523.32 Chronic periodontitis Digestive 0.877 0.739 – 1.04 0.134 143 1470 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.89 0.707 – 1.12 0.318 79 881 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.933 0.736 – 1.18 0.567 77 793 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.95 0.871 – 1.04 0.251 545 6749 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.828 0.5 – 1.37 0.463 14 186 exclusion phecode
526 Diseases of the jaws Digestive 0.938 0.81 – 1.09 0.392 203 2461 exclusion phecode
526.1 Cysts of the jaws Digestive 0.998 0.8 – 1.24 0.984 94 853 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.704 0.437 – 1.13 0.149 13 177 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 0.982 0.727 – 1.33 0.904 47 636 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.968 0.716 – 1.31 0.834 47 618 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 1.01 0.652 – 1.57 0.955 22 295 exclusion phecode
526.9 Jaw disease NOS Digestive 0.808 0.573 – 1.14 0.225 34 573 exclusion phecode
527 Diseases of the salivary glands Digestive 1.02 0.861 – 1.22 0.787 132 1818 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.4 0.84 – 2.32 0.198 18 228 exclusion phecode
527.2 Sialoadenitis Digestive 0.92 0.729 – 1.16 0.478 74 929 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 0.992 0.575 – 1.71 0.977 11 175 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.49 1.02 – 2.19 0.0408 27 288 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.03 0.958 – 1.11 0.419 798 10115 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.01 0.786 – 1.3 0.942 64 1231 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.09 0.828 – 1.43 0.54 53 1020 exclusion phecode
528.12 Oral aphthae Digestive 0.777 0.461 – 1.31 0.345 12 212 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.08 0.802 – 1.47 0.598 43 467 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 1 0.702 – 1.43 0.998 31 345 exclusion phecode
528.41 Cyst of the salivary gland Digestive 1.12 0.762 – 1.66 0.555 25 259 exclusion phecode
528.5 Diseases of lips Digestive 1 0.847 – 1.19 0.964 141 1806 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.16 0.899 – 1.49 0.259 66 736 exclusion phecode
528.7 Sialolithiasis Digestive 1.22 0.955 – 1.57 0.109 64 802 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.03 0.902 – 1.19 0.632 223 3163 exclusion phecode
529.1 Glossitis Digestive 1.09 0.811 – 1.47 0.563 41 773 exclusion phecode
530 Diseases of esophagus Digestive 0.991 0.966 – 1.02 0.51 6342 73619 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.988 0.962 – 1.01 0.359 5971 71739 exclusion phecode
530.11 GERD Digestive 0.972 0.943 – 1 0.0726 4454 58697 exclusion phecode
530.12 Ulcer of esophagus Digestive 0.951 0.888 – 1.02 0.15 887 13200 exclusion phecode
530.14 Reflux esophagitis Digestive 0.987 0.944 – 1.03 0.547 2130 26891 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.01 0.891 – 1.15 0.835 232 4307 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 0.998 0.898 – 1.11 0.972 355 4713 exclusion phecode
530.5 Disorders of esophageal motility Digestive 0.819 0.692 – 0.968 0.0191 136 1642 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.993 0.688 – 1.43 0.969 29 367 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.949 0.715 – 1.26 0.717 47 825 exclusion phecode
530.9 Heartburn Digestive 0.929 0.841 – 1.03 0.148 427 5551 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1 0.945 – 1.07 0.898 1096 17512 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.961 0.778 – 1.19 0.711 89 1505 exclusion phecode
531.2 Gastric ulcer Digestive 1.04 0.965 – 1.13 0.281 636 10031 exclusion phecode
531.3 Duodenal ulcer Digestive 0.959 0.872 – 1.05 0.388 450 7322 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.1 0.828 – 1.46 0.517 45 978 exclusion phecode
532 Dysphagia Digestive 1 0.94 – 1.06 0.989 1080 16582 exclusion phecode
535 Gastritis and duodenitis Digestive 1.01 0.986 – 1.04 0.337 5208 68217 exclusion phecode
535.1 Acute gastritis Digestive 0.929 0.81 – 1.07 0.293 220 2947 exclusion phecode
535.2 Atrophic gastritis Digestive 1.08 0.84 – 1.39 0.551 62 868 exclusion phecode
535.6 Duodenitis Digestive 0.965 0.914 – 1.02 0.203 1397 19254 exclusion phecode
535.8 Other specified gastritis Digestive 1.03 0.974 – 1.08 0.339 1504 20373 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.958 0.644 – 1.43 0.833 26 284 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.07 0.78 – 1.47 0.673 42 580 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 0.921 0.844 – 1 0.0629 550 8487 exclusion phecode
540 Appendiceal conditions Digestive 1.02 0.945 – 1.1 0.614 727 7923 exclusion phecode
540.1 Appendicitis Digestive 1.01 0.929 – 1.09 0.897 690 7428 exclusion phecode
540.11 Acute appendicitis Digestive 1.01 0.926 – 1.09 0.892 630 6587 exclusion phecode
550 Abdominal hernia Digestive 1 0.979 – 1.02 0.993 9447 74083 exclusion phecode
550.1 Inguinal hernia Digestive 0.998 0.965 – 1.03 0.919 3756 32050 exclusion phecode
550.2 Diaphragmatic hernia Digestive 0.993 0.965 – 1.02 0.626 5052 62598 exclusion phecode
550.3 Femoral hernia Digestive 0.913 0.773 – 1.08 0.285 144 1649 exclusion phecode
550.4 Umbilical hernia Digestive 1.01 0.933 – 1.09 0.835 690 9574 exclusion phecode
550.5 Ventral hernia Digestive 1.04 0.962 – 1.13 0.318 638 8772 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 0.968 0.906 – 1.03 0.331 954 11569 exclusion phecode
555.1 Regional enteritis Digestive 0.911 0.816 – 1.02 0.0947 343 4509 exclusion phecode
555.2 Ulcerative colitis Digestive 0.988 0.915 – 1.07 0.76 702 8197 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 0.98 0.814 – 1.18 0.828 123 1404 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.04 0.907 – 1.2 0.546 212 2745 exclusion phecode
556.1 Ulceration of intestine Digestive 1.01 0.847 – 1.2 0.928 132 1706 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.943 0.748 – 1.19 0.62 84 806 exclusion phecode
557.1 Celiac disease Digestive 0.988 0.895 – 1.09 0.809 440 4910 exclusion phecode
558 Noninfectious gastroenteritis Digestive 0.966 0.93 – 1 0.0744 2884 40649 exclusion phecode
559 Ileostomy status Digestive 0.99 0.882 – 1.11 0.868 302 4277 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 0.987 0.914 – 1.07 0.729 700 10054 exclusion phecode
560.1 Paralytic ileus Digestive 1 0.802 – 1.25 0.993 84 1267 exclusion phecode
560.2 Impaction of intestine Digestive 0.705 0.492 – 1.01 0.0562 31 664 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.06 0.909 – 1.25 0.439 167 2220 exclusion phecode
560.4 Other intestinal obstruction Digestive 0.994 0.916 – 1.08 0.879 621 8653 exclusion phecode
561 Symptoms involving digestive system Digestive 1.04 1.01 – 1.08 0.0182 3382 41675 exclusion phecode
561.1 Diarrhea Digestive 1.07 0.869 – 1.32 0.52 102 1177 exclusion phecode
561.2 Flatulence Digestive 1.1 0.985 – 1.24 0.0888 325 4571 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1.02 0.991 – 1.05 0.193 5568 56658 exclusion phecode
562.1 Diverticulosis Digestive 1.02 0.991 – 1.05 0.196 5561 56640 exclusion phecode
563 Constipation Digestive 0.988 0.939 – 1.04 0.649 1615 26715 exclusion phecode
564 Functional digestive disorders Digestive 1.02 0.989 – 1.05 0.199 4274 55638 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.02 0.96 – 1.09 0.476 1037 14612 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.01 0.899 – 1.13 0.871 298 4304 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.02 0.984 – 1.06 0.269 3010 39451 exclusion phecode
565 Anal and rectal conditions Digestive 1.02 0.981 – 1.06 0.361 3088 37377 exclusion phecode
565.1 Anal and rectal polyp Digestive 1 0.953 – 1.06 0.905 1559 18479 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 0.973 0.809 – 1.17 0.77 116 2307 exclusion phecode
568 Other disorders of peritoneum Digestive 0.948 0.873 – 1.03 0.203 604 8269 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.963 0.885 – 1.05 0.386 576 7823 exclusion phecode
569 Other disorders of intestine Digestive 1.01 0.934 – 1.09 0.857 735 10611 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.767 0.46 – 1.28 0.31 14 377 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.07 0.872 – 1.32 0.503 93 1279 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 0.951 0.853 – 1.06 0.37 346 7580 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 0.821 0.718 – 0.937 0.00353 235 4266 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.35 0.84 – 2.16 0.217 16 270 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.19 0.856 – 1.65 0.302 35 625 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.18 0.944 – 1.47 0.148 77 2536 exclusion phecode
571.81 Portal hypertension Digestive 0.841 0.599 – 1.18 0.316 32 1353 exclusion phecode
572 Ascites (non malignant) Digestive 0.951 0.789 – 1.15 0.602 109 3834 exclusion phecode
573 Other disorders of liver Digestive 1.01 0.877 – 1.16 0.888 201 3893 exclusion phecode
573.2 Liver replaced by transplant Digestive 0.725 0.424 – 1.24 0.24 13 215 exclusion phecode
573.3 Hepatomegaly Digestive 1.19 0.834 – 1.71 0.333 26 746 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.13 0.955 – 1.33 0.157 142 2268 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.06 0.973 – 1.15 0.181 554 8740 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 0.913 0.628 – 1.33 0.635 27 520 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 0.966 0.931 – 1 0.0644 3097 40002 exclusion phecode
574.1 Cholelithiasis Digestive 0.96 0.922 – 0.998 0.0416 2651 34734 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.983 0.873 – 1.11 0.777 285 3792 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.956 0.898 – 1.02 0.149 1081 13841 exclusion phecode
574.2 Calculus of bile duct Digestive 1.05 0.962 – 1.16 0.259 494 6526 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.889 0.813 – 0.971 0.00924 533 6918 exclusion phecode
575 Other biliary tract disease Digestive 0.953 0.881 – 1.03 0.223 676 9730 exclusion phecode
575.1 Cholangitis Digestive 1.22 0.954 – 1.56 0.112 66 1193 exclusion phecode
575.2 Obstruction of bile duct Digestive 0.894 0.738 – 1.08 0.249 105 1928 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.848 0.684 – 1.05 0.133 92 1163 exclusion phecode
575.7 Other disorders of gallbladder Digestive 0.92 0.818 – 1.04 0.169 290 3570 exclusion phecode
575.8 Other disorders of biliary tract Digestive 0.887 0.757 – 1.04 0.14 160 2644 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.22 0.897 – 1.67 0.202 42 830 exclusion phecode
577 Diseases of pancreas Digestive 0.954 0.861 – 1.06 0.359 384 6739 exclusion phecode
577.1 Acute pancreatitis Digestive 0.936 0.837 – 1.05 0.248 310 5027 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.03 0.764 – 1.4 0.832 42 1287 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.881 0.66 – 1.18 0.391 45 924 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1 0.97 – 1.03 0.905 4077 52942 exclusion phecode
578.1 Hematemesis Digestive 1.02 0.889 – 1.18 0.736 193 4914 exclusion phecode
578.2 Blood in stool Digestive 1.07 0.968 – 1.19 0.179 383 6513 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 0.979 0.942 – 1.02 0.28 2793 33689 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.05 0.987 – 1.12 0.118 988 13585 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.04 0.922 – 1.18 0.508 272 3992 exclusion phecode
579.2 Splenomegaly Digestive 0.927 0.705 – 1.22 0.589 52 1099 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.02 0.921 – 1.14 0.682 384 4333 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.07 0.92 – 1.25 0.373 175 3827 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.04 0.862 – 1.26 0.678 114 2617 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.24 0.672 – 2.28 0.493 11 191 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.03 0.667 – 1.59 0.894 23 338 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.04 0.842 – 1.29 0.706 86 2178 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.32 0.999 – 1.75 0.0511 51 1164 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.13 0.827 – 1.54 0.448 37 634 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.15 0.851 – 1.56 0.357 38 650 exclusion phecode
585 Renal failure Genitourinary 0.89 0.825 – 0.961 0.00303 684 17264 exclusion phecode
585.1 Acute renal failure Genitourinary 0.937 0.841 – 1.04 0.23 341 11278 exclusion phecode
585.2 Renal failure NOS Genitourinary 0.908 0.774 – 1.06 0.231 157 3627 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.84 0.745 – 0.947 0.0043 290 6513 exclusion phecode
585.31 Renal dialysis Genitourinary 0.978 0.762 – 1.25 0.861 65 1270 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 0.96 0.879 – 1.05 0.362 523 8522 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.18 0.834 – 1.68 0.347 30 531 exclusion phecode
586.11 Small kidney Genitourinary 1.28 0.886 – 1.86 0.186 26 448 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 0.976 0.844 – 1.13 0.739 192 3139 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.59 0.288 – 1.21 0.151 6 192 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.955 0.81 – 1.12 0.581 150 2365 exclusion phecode
587 Kidney replaced by transpant Genitourinary 0.991 0.768 – 1.28 0.945 63 940 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 0.823 0.512 – 1.32 0.42 17 254 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.02 0.627 – 1.65 0.942 17 293 exclusion phecode
590 Pyelonephritis Genitourinary 0.996 0.866 – 1.14 0.95 222 3463 exclusion phecode
591 Urinary tract infection Genitourinary 0.972 0.929 – 1.02 0.227 2008 31358 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.02 0.929 – 1.11 0.739 534 7343 exclusion phecode
592.1 Cystitis Genitourinary 1.03 0.942 – 1.13 0.515 530 7173 exclusion phecode
592.11 Acute cystitis Genitourinary 1.06 0.711 – 1.58 0.775 24 353 exclusion phecode
592.12 Chronic cystitis Genitourinary 1.06 0.906 – 1.25 0.448 154 2221 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.19 0.901 – 1.58 0.218 53 576 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.826 0.557 – 1.22 0.34 25 449 exclusion phecode
593 Hematuria Genitourinary 1.02 0.981 – 1.05 0.371 3413 40838 exclusion phecode
594 Urinary calculus Genitourinary 0.952 0.9 – 1.01 0.089 1328 16182 exclusion phecode
594.1 Calculus of kidney Genitourinary 0.981 0.905 – 1.06 0.644 630 8051 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 0.951 0.805 – 1.12 0.551 152 1900 exclusion phecode
594.3 Calculus of ureter Genitourinary 0.973 0.889 – 1.06 0.545 502 6024 exclusion phecode
594.8 Renal colic Genitourinary 0.953 0.862 – 1.05 0.344 426 5162 exclusion phecode
595 Hydronephrosis Genitourinary 1.04 0.922 – 1.17 0.533 277 4943 exclusion phecode
596 Other disorders of bladder Genitourinary 0.956 0.912 – 1 0.0543 1938 24536 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 0.923 0.835 – 1.02 0.12 411 4916 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 0.967 0.855 – 1.09 0.596 270 4289 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.974 0.906 – 1.05 0.481 787 9812 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.991 0.916 – 1.07 0.825 662 8295 exclusion phecode
597.2 Urinary complications NEC Genitourinary 0.879 0.442 – 1.75 0.713 6 217 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.01 0.938 – 1.09 0.739 711 8899 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.16 0.858 – 1.56 0.336 46 723 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.98 0.947 – 1.01 0.257 3516 47518 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.867 0.597 – 1.26 0.454 33 397 exclusion phecode
599.2 Retention of urine Genitourinary 0.955 0.9 – 1.01 0.119 1192 17032 exclusion phecode
599.3 Dysuria Genitourinary 0.961 0.842 – 1.1 0.562 224 3072 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.976 0.927 – 1.03 0.346 1617 22789 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 0.988 0.918 – 1.06 0.749 762 10271 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.13 0.695 – 1.85 0.615 14 263 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.43 0.787 – 2.58 0.242 15 156 exclusion phecode
599.9 Other abnormality of urination Genitourinary 0.884 0.795 – 0.982 0.0212 351 4802 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.989 0.948 – 1.03 0.602 2428 22746 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 1.02 0.927 – 1.13 0.671 444 5263 exclusion phecode
601.1 Prostatitis Genitourinary 0.988 0.886 – 1.1 0.829 355 4038 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.804 0.6 – 1.08 0.143 51 627 exclusion phecode
601.12 Chronic prostatitis Genitourinary 0.983 0.852 – 1.13 0.811 206 2341 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 1.09 0.609 – 1.97 0.763 9 133 exclusion phecode
601.4 Balanoposthitis Genitourinary 1.02 0.763 – 1.37 0.88 47 658 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.34 1.01 – 1.77 0.043 50 740 exclusion phecode
602 Other disorders of prostate Genitourinary 0.906 0.805 – 1.02 0.0985 300 3301 exclusion phecode
603 Other disorders of testis Genitourinary 0.885 0.8 – 0.979 0.0179 407 5394 exclusion phecode
603.1 Hydrocele Genitourinary 0.865 0.764 – 0.978 0.021 272 3332 exclusion phecode
604 Disorders of penis Genitourinary 0.928 0.855 – 1.01 0.0755 617 8267 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.901 0.824 – 0.985 0.022 517 6883 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 1.04 0.778 – 1.39 0.785 48 689 exclusion phecode
608 Other disorders of male genital organs Genitourinary 1.03 0.941 – 1.12 0.57 567 7076 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.4 1.03 – 1.91 0.0316 54 490 exclusion phecode
609.1 Infertility, male Genitourinary 1.8 0.87 – 3.73 0.113 8 150 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 1.16 0.855 – 1.58 0.334 46 400 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.943 0.869 – 1.02 0.156 633 6566 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.855 0.749 – 0.977 0.0209 235 2348 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 0.798 0.634 – 1 0.0541 77 829 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 0.914 0.734 – 1.14 0.42 85 796 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.994 0.892 – 1.11 0.906 360 3654 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.11 0.935 – 1.32 0.23 141 1760 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.02 0.923 – 1.14 0.657 396 4173 exclusion phecode
611.1 Abnormal mammogram Genitourinary 1.05 0.574 – 1.91 0.88 10 148 exclusion phecode
611.3 Lump or mass in breast Genitourinary 1.02 0.918 – 1.13 0.708 387 4023 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.03 0.886 – 1.2 0.686 179 2366 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.06 0.907 – 1.24 0.471 167 2246 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary – 16 198 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.988 0.891 – 1.1 0.813 393 4263 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.05 0.894 – 1.22 0.58 164 1805 exclusion phecode
613.5 Mastodynia Genitourinary 1.22 0.749 – 1.98 0.428 17 206 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary – 174 1745 exclusion phecode
613.8 Other specified disorders of breast Genitourinary – 63 857 exclusion phecode
613.9 Breast disorder NOS Genitourinary 0.769 0.597 – 0.99 0.0414 64 552 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1 0.947 – 1.06 0.923 1299 15483 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.93 0.853 – 1.01 0.0999 553 6746 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.99 0.849 – 1.15 0.893 178 2238 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.816 0.427 – 1.56 0.537 8 190 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.05 0.844 – 1.31 0.659 91 1113 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.02 0.811 – 1.29 0.852 74 920 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.3 0.991 – 1.69 0.058 63 751 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.03 0.948 – 1.12 0.483 618 7117 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.01 0.896 – 1.14 0.888 304 3576 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.18 0.952 – 1.46 0.131 97 1162 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.997 0.859 – 1.16 0.965 191 2028 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.13 0.839 – 1.52 0.426 48 723 exclusion phecode
615 Endometriosis Genitourinary 1.06 0.989 – 1.13 0.102 983 11050 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.06 0.805 – 1.39 0.684 54 782 exclusion phecode
618 Genital prolapse Genitourinary 0.959 0.921 – 0.998 0.0398 2592 29994 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.984 0.935 – 1.04 0.548 1583 18813 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.938 0.885 – 0.994 0.0301 1234 13805 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.09 0.914 – 1.3 0.331 130 1302 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.985 0.822 – 1.18 0.867 128 1754 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1.04 0.993 – 1.09 0.0947 2109 23263 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.18 1.01 – 1.38 0.0402 176 1935 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 0.969 0.901 – 1.04 0.399 802 8838 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.01 0.939 – 1.09 0.725 721 7726 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.06 0.958 – 1.17 0.263 424 4592 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.11 0.99 – 1.25 0.0739 320 3526 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 0.904 0.558 – 1.47 0.683 16 158 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.979 0.867 – 1.11 0.727 281 2913 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.974 0.936 – 1.01 0.193 2773 27717 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.99 0.946 – 1.04 0.673 2054 20820 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 0.917 0.856 – 0.982 0.0135 929 8888 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 0.942 0.84 – 1.06 0.309 321 3395 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.952 0.814 – 1.11 0.539 173 1982 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 1.01 0.759 – 1.35 0.929 48 580 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 0.836 0.681 – 1.03 0.0876 103 1118 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.996 0.94 – 1.06 0.906 1225 15344 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.06 0.975 – 1.14 0.18 663 7857 exclusion phecode
625.1 Dyspareunia Genitourinary 0.963 0.846 – 1.09 0.56 248 3240 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.04 1 – 1.07 0.0409 4001 32520 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.03 0.998 – 1.07 0.0638 3470 31274 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.842 0.544 – 1.3 0.442 21 326 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1.03 0.986 – 1.08 0.186 2267 25618 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 1.03 0.936 – 1.13 0.564 494 5369 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 1.06 0.99 – 1.13 0.1 1014 10779 exclusion phecode
626.2 Dysmenorrhea Genitourinary 1.06 0.957 – 1.18 0.257 387 4942 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 1.05 0.722 – 1.51 0.815 27 447 exclusion phecode
626.8 Infertility, female Genitourinary 1.11 1.01 – 1.24 0.0388 405 3754 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.996 0.956 – 1.04 0.85 2494 26982 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 0.99 0.947 – 1.03 0.651 2159 23326 exclusion phecode
627.2 Symptomatic menopause Genitourinary 1.05 0.765 – 1.45 0.755 43 460 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.95 0.829 – 1.09 0.454 232 2670 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 0.843 0.675 – 1.05 0.132 85 841 exclusion phecode
628 Ovarian cyst Genitourinary 0.999 0.94 – 1.06 0.981 1098 12761 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.09 1.03 – 1.15 0.00459 1398 9828 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.06 0.946 – 1.19 0.313 318 3013 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.12 0.896 – 1.41 0.313 78 892 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1.01 0.92 – 1.11 0.857 524 4654 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.908 0.795 – 1.04 0.155 245 2277 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.07 0.954 – 1.2 0.244 324 3278 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.03 0.946 – 1.12 0.481 585 5315 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.989 0.842 – 1.16 0.893 164 1609 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.05 0.922 – 1.2 0.451 239 2847 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 1.24 0.735 – 2.1 0.419 14 188 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.893 0.792 – 1.01 0.065 300 2935 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.993 0.789 – 1.25 0.952 82 818 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.03 0.808 – 1.32 0.789 65 573 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1 0.752 – 1.34 0.978 46 397 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.07 0.961 – 1.19 0.218 371 3323 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.95 0.869 – 1.04 0.25 548 5584 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.05 0.679 – 1.64 0.814 18 186 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1 0.767 – 1.31 0.993 57 708 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.856 0.595 – 1.23 0.403 31 290 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.936 0.686 – 1.28 0.678 45 539 exclusion phecode
650 Normal delivery Pregnancy Complications 1.05 0.96 – 1.16 0.271 517 5050 exclusion phecode
651 Multiple gestation Pregnancy Complications 0.972 0.784 – 1.2 0.793 105 914 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1.04 0.942 – 1.14 0.466 473 4369 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.938 0.844 – 1.04 0.239 384 3680 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.2 0.754 – 1.92 0.436 18 205 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.985 0.926 – 1.05 0.63 1215 7855 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.996 0.667 – 1.49 0.985 26 282 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 1.01 0.936 – 1.1 0.737 707 4734 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.982 0.826 – 1.17 0.84 138 1387 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.999 0.945 – 1.06 0.968 1573 7729 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.02 0.941 – 1.1 0.675 741 5454 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.19 0.875 – 1.61 0.269 49 423 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.1 0.854 – 1.41 0.467 62 669 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.14 0.658 – 1.98 0.639 12 150 exclusion phecode
679 Complications of in utero procedures Dermatologic 0.842 0.491 – 1.45 0.533 11 149 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.01 0.955 – 1.07 0.674 1193 18300 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.11 0.906 – 1.36 0.316 99 1435 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.02 0.843 – 1.24 0.839 118 1315 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1 0.937 – 1.07 0.917 864 13866 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.01 0.941 – 1.08 0.821 866 13851 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1 0.936 – 1.07 0.937 859 13751 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.03 0.835 – 1.26 0.801 93 1475 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 0.879 0.77 – 1 0.055 230 3364 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 0.985 0.892 – 1.09 0.768 412 5929 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.1 0.906 – 1.34 0.333 103 1456 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.03 0.832 – 1.28 0.776 87 949 exclusion phecode
687 Symptoms affecting skin Dermatologic 1.12 0.923 – 1.35 0.258 109 1434 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.959 0.862 – 1.07 0.438 364 5491 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.02 0.794 – 1.3 0.897 65 720 exclusion phecode
687.3 Changes in skin texture Dermatologic 1.14 0.78 – 1.68 0.491 22 281 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.01 0.925 – 1.11 0.768 473 7543 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.993 0.938 – 1.05 0.803 1313 14415 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.833 0.464 – 1.5 0.542 12 188 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.781 0.412 – 1.48 0.449 9 141 exclusion phecode
691 Congenital anomalies of skin Dermatologic 1.07 0.738 – 1.54 0.734 30 304 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 1.07 0.934 – 1.21 0.346 242 2475 exclusion phecode
694.1 Vitiligo Dermatologic 1.07 0.633 – 1.79 0.813 14 163 exclusion phecode
694.2 Other dyschromia Dermatologic 1.08 0.931 – 1.24 0.322 201 1984 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.02 0.649 – 1.59 0.944 21 282 exclusion phecode
695 Erythematous conditions Dermatologic 0.999 0.909 – 1.1 0.985 473 6023 exclusion phecode
695.1 Toxic erythema Dermatologic 1.06 0.7 – 1.61 0.774 24 267 exclusion phecode
695.2 Bullous dermatoses Dermatologic 0.729 0.492 – 1.08 0.115 27 325 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 1.1 0.634 – 1.91 0.734 12 139 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.606 0.37 – 0.994 0.0472 16 175 exclusion phecode
695.3 Rosacea Dermatologic 0.963 0.762 – 1.22 0.753 72 734 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.19 0.944 – 1.51 0.14 74 1041 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.13 0.698 – 1.84 0.611 15 316 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.23 0.961 – 1.58 0.0993 68 869 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 1.04 0.89 – 1.21 0.643 176 2011 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1.05 0.789 – 1.4 0.741 47 608 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.718 0.442 – 1.17 0.182 19 208 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 0.872 0.669 – 1.14 0.312 61 1154 exclusion phecode
696 Psoriasis and related disorders Dermatologic 1.12 1.01 – 1.24 0.0316 385 5658 exclusion phecode
696.4 Psoriasis Dermatologic 1.12 1.01 – 1.25 0.0352 371 5537 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 1.14 1.01 – 1.29 0.0381 269 4216 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 1.04 0.866 – 1.25 0.662 119 1890 exclusion phecode
697 Sarcoidosis Dermatologic 0.894 0.738 – 1.08 0.249 114 1418 exclusion phecode
698 Pruritus and related conditions Dermatologic 1.16 0.983 – 1.36 0.0803 155 1991 exclusion phecode
700 Corns and callosities Dermatologic 1.13 0.85 – 1.5 0.398 51 695 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.1 1.03 – 1.17 0.0049 1030 11941 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.913 0.557 – 1.5 0.719 16 219 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.07 0.98 – 1.17 0.129 515 5983 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 1.24 0.657 – 2.33 0.511 11 143 exclusion phecode
701.4 Keloid scar Dermatologic 1.02 0.742 – 1.39 0.921 42 593 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1.14 0.932 – 1.4 0.202 98 1223 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 0.993 0.675 – 1.46 0.972 29 223 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.06 1 – 1.12 0.0503 1340 13590 exclusion phecode
702.1 Actinic keratosis Dermatologic 1.07 0.987 – 1.17 0.0963 607 6368 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 1.05 0.976 – 1.13 0.186 766 7624 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.04 0.83 – 1.31 0.723 70 884 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.947 0.804 – 1.12 0.514 150 2476 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.995 0.938 – 1.05 0.863 1188 13572 exclusion phecode
704.1 Alopecia Dermatologic 0.76 0.506 – 1.14 0.188 26 313 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.974 0.638 – 1.49 0.902 22 198 exclusion phecode
705 Disorders of sweat glands Dermatologic 1.04 0.765 – 1.41 0.811 40 595 exclusion phecode
705.3 Hidradenitis Dermatologic 1.11 0.791 – 1.55 0.552 32 486 exclusion phecode
705.8 Hyperhidrosis Dermatologic 0.858 0.706 – 1.04 0.126 102 1520 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1.01 0.965 – 1.06 0.632 1853 21297 exclusion phecode
706.1 Acne Dermatologic 1.33 0.799 – 2.22 0.272 13 197 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1.02 0.971 – 1.06 0.475 1951 22241 exclusion phecode
707 Chronic ulcer of skin Dermatologic 0.928 0.784 – 1.1 0.38 136 4786 exclusion phecode
707.1 Decubitus ulcer Dermatologic 0.807 0.595 – 1.1 0.171 37 2160 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.991 0.919 – 1.07 0.809 744 8736 exclusion phecode
709.2 Sicca syndrome Dermatologic 0.998 0.816 – 1.22 0.982 104 1309 exclusion phecode
709.3 Systemic sclerosis Dermatologic 1.13 0.803 – 1.58 0.49 32 454 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.77 0.957 – 3.26 0.0689 11 162 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.981 0.902 – 1.07 0.646 603 6920 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.96 0.787 – 1.17 0.691 100 1587 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 0.94 0.761 – 1.16 0.564 89 1483 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.905 0.627 – 1.3 0.591 35 482 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.01 0.781 – 1.29 0.968 59 1091 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 1.13 0.876 – 1.45 0.355 62 1159 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.21 0.908 – 1.62 0.193 46 894 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.28 0.806 – 2.03 0.294 15 216 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.35 0.806 – 2.26 0.255 13 387 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.19 0.447 – 3.17 0.727 0 181 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.03 0.954 – 1.11 0.468 746 12478 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.01 0.934 – 1.09 0.819 673 11266 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.01 0.887 – 1.14 0.92 258 4304 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.05 0.648 – 1.7 0.84 15 311 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.05 0.873 – 1.26 0.613 120 1575 exclusion phecode
716 Other arthropathies Musculoskeletal 1.05 1.02 – 1.08 0.000158 6812 71088 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.11 1.02 – 1.21 0.0176 587 9066 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.05 1.01 – 1.09 0.0207 2935 40438 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.05 1.02 – 1.07 0.000441 6514 70244 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.05 0.914 – 1.2 0.515 231 2682 exclusion phecode
720 Spinal stenosis Musculoskeletal 0.999 0.922 – 1.08 0.989 644 9271 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 0.99 0.935 – 1.05 0.73 1261 19608 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.97 0.904 – 1.04 0.395 819 12490 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.22 0.871 – 1.7 0.249 31 528 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 1.01 0.774 – 1.31 0.955 57 846 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.02 0.973 – 1.07 0.39 1726 23175 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.06 0.854 – 1.32 0.589 91 1320 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.07 0.973 – 1.17 0.171 503 7313 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 0.771 0.429 – 1.39 0.385 9 184 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.996 0.93 – 1.07 0.914 882 11262 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.24 0.988 – 1.55 0.0638 77 1272 exclusion phecode
723.1 Torticollis Musculoskeletal 1.31 0.835 – 2.06 0.239 17 256 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 0.973 0.875 – 1.08 0.617 363 5321 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 0.888 0.711 – 1.11 0.297 78 1055 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.901 0.72 – 1.13 0.36 78 1063 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 0.979 0.54 – 1.77 0.944 12 159 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.01 0.893 – 1.14 0.889 275 4164 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.04 1 – 1.08 0.0475 3016 38060 exclusion phecode
726.1 Enthesopathy Musculoskeletal 1 0.959 – 1.05 0.853 1987 24646 exclusion phecode
726.2 Synoviopathy Musculoskeletal 1 0.8 – 1.26 0.968 78 917 exclusion phecode
726.3 Bursitis Musculoskeletal 0.92 0.783 – 1.08 0.313 158 2156 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.01 0.964 – 1.07 0.573 1603 19040 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.952 0.872 – 1.04 0.269 553 7126 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.943 0.631 – 1.41 0.774 26 262 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.02 0.948 – 1.1 0.554 735 8150 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 1.23 1.02 – 1.47 0.0313 118 1511 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.24 0.972 – 1.59 0.0824 69 904 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.703 0.474 – 1.04 0.079 23 404 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.19 1.11 – 1.28 1.56e-06 810 9240 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.04 0.853 – 1.27 0.698 100 1114 exclusion phecode
728.7 Fasciitis Musculoskeletal 1.16 1.08 – 1.25 4.36e-05 828 9606 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.19 1.11 – 1.29 3.19e-06 767 8680 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.06 0.99 – 1.13 0.0976 958 15389 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.963 0.809 – 1.15 0.668 126 2631 exclusion phecode
729.3 Panniculitis Musculoskeletal 1.06 0.705 – 1.59 0.785 19 266 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.07 0.831 – 1.38 0.6 65 761 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.12 0.866 – 1.46 0.379 61 732 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.813 0.665 – 0.994 0.0436 105 1219 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.828 0.614 – 1.11 0.213 47 542 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.62 0.363 – 1.06 0.0799 13 155 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.02 0.915 – 1.13 0.757 371 4528 exclusion phecode
733.2 Cyst of bone Musculoskeletal 0.881 0.691 – 1.12 0.307 66 779 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.26 1.04 – 1.53 0.0168 109 1333 exclusion phecode
733.6 Costochondritis Musculoskeletal 1.06 0.637 – 1.76 0.824 13 333 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.987 0.866 – 1.12 0.842 237 3258 exclusion phecode
733.9 Chondromalacia Musculoskeletal 0.776 0.5 – 1.2 0.255 20 327 exclusion phecode
735 Acquired foot deformities Musculoskeletal 0.961 0.919 – 1 0.0781 2164 24807 exclusion phecode
735.1 Flat foot Musculoskeletal 1.04 0.785 – 1.38 0.786 51 528 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 0.948 0.891 – 1.01 0.0948 1083 12760 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.94 0.849 – 1.04 0.239 399 4877 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.935 0.837 – 1.04 0.234 344 3957 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.973 0.923 – 1.03 0.309 1517 17143 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1.05 0.933 – 1.17 0.437 320 4091 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 0.715 0.516 – 0.991 0.0438 40 603 exclusion phecode
737 Curvature of spine Musculoskeletal 0.926 0.8 – 1.07 0.298 188 2749 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.941 0.81 – 1.09 0.425 176 2556 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.95 0.853 – 1.06 0.357 350 4807 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.925 0.818 – 1.05 0.22 272 3722 exclusion phecode
739 Contracture of joint Musculoskeletal 0.947 0.765 – 1.17 0.617 89 1208 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.02 0.99 – 1.05 0.21 5273 60354 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.02 0.989 – 1.06 0.184 3556 42723 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.02 0.976 – 1.07 0.336 1810 22083 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.999 0.786 – 1.27 0.994 69 913 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.773 0.607 – 0.985 0.0372 62 1582 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.02 0.974 – 1.07 0.406 2043 30776 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.997 0.921 – 1.08 0.939 658 9105 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 1.15 0.73 – 1.82 0.542 14 263 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.1 0.916 – 1.33 0.297 115 1565 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 1.09 0.633 – 1.89 0.748 10 392 exclusion phecode
741.4 Joint effusions Musculoskeletal 0.99 0.867 – 1.13 0.877 230 3651 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 0.771 0.505 – 1.18 0.229 18 288 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.654 0.366 – 1.17 0.151 10 127 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.997 0.918 – 1.08 0.949 604 7450 exclusion phecode
742.1 Loose body in joint Musculoskeletal 0.939 0.746 – 1.18 0.595 77 881 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.21 0.763 – 1.91 0.421 18 243 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 0.985 0.793 – 1.22 0.889 89 1332 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 1 0.908 – 1.11 0.97 429 5171 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.971 0.918 – 1.03 0.305 1317 18376 exclusion phecode
743.1 Osteoporosis Musculoskeletal 0.981 0.922 – 1.04 0.535 1089 15385 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 0.979 0.916 – 1.05 0.536 937 13345 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1.15 0.922 – 1.43 0.219 82 1292 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.07 0.833 – 1.37 0.605 66 1248 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.861 0.74 – 1 0.0535 180 2066 exclusion phecode
745 Pain in joint Musculoskeletal 1.05 0.995 – 1.11 0.0748 1406 20382 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.93 0.847 – 1.02 0.131 470 6788 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.954 0.865 – 1.05 0.341 432 6367 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.829 0.686 – 1 0.0505 118 1506 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.12 0.841 – 1.48 0.446 47 628 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.966 0.852 – 1.1 0.597 256 4210 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.69 0.485 – 0.981 0.039 34 428 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.17 0.706 – 1.94 0.541 12 134 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.06 0.825 – 1.37 0.641 69 744 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.837 0.712 – 0.985 0.0324 163 1718 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.779 0.609 – 0.997 0.0474 71 805 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.872 0.62 – 1.22 0.429 39 467 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.901 0.724 – 1.12 0.349 89 923 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.919 0.692 – 1.22 0.563 58 592 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.978 0.694 – 1.38 0.899 29 301 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.06 0.948 – 1.18 0.314 358 4024 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.29 1.1 – 1.51 0.00177 166 1875 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.32 1.08 – 1.6 0.00574 115 1265 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.4 1.05 – 1.87 0.0205 48 601 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.944 0.812 – 1.1 0.454 190 2143 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.943 0.76 – 1.17 0.599 88 1070 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.988 0.783 – 1.25 0.919 80 855 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.936 0.718 – 1.22 0.622 56 876 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 0.935 0.696 – 1.26 0.657 46 683 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.938 0.679 – 1.3 0.699 39 589 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.773 0.44 – 1.36 0.369 9 214 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.888 0.635 – 1.24 0.485 37 313 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.14 0.717 – 1.81 0.583 20 196 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.74 0.471 – 1.16 0.192 18 291 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.11 0.902 – 1.36 0.328 95 1160 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.3 0.966 – 1.76 0.0829 43 556 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.913 0.666 – 1.25 0.568 38 411 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.12 0.743 – 1.67 0.598 26 274 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.01 0.829 – 1.23 0.924 107 1542 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.99 0.645 – 1.52 0.963 21 212 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.985 0.778 – 1.25 0.897 74 1119 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.961 0.69 – 1.34 0.812 37 456 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.861 0.49 – 1.51 0.603 11 214 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.886 0.68 – 1.15 0.369 57 591 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.999 0.677 – 1.48 0.997 31 264 exclusion phecode
760 Back pain Symptoms 0.969 0.924 – 1.02 0.199 1792 28489 exclusion phecode
761 Cervicalgia Symptoms 1.01 0.896 – 1.14 0.86 282 4588 exclusion phecode
764 Sciatica Symptoms 1.06 0.962 – 1.17 0.236 435 6052 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.01 0.877 – 1.17 0.857 197 3005 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.03 0.844 – 1.25 0.788 99 1565 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.05 0.904 – 1.22 0.509 181 2216 exclusion phecode
771.1 Swelling of limb Symptoms 1.06 0.982 – 1.14 0.136 749 11658 exclusion phecode
772 Symptoms of the muscles Symptoms 1.09 0.887 – 1.33 0.418 96 1628 exclusion phecode
773 Pain in limb Symptoms 1.03 0.972 – 1.1 0.285 1056 15834 exclusion phecode
780 Hypothermia/Chills Symptoms 1.74 1.07 – 2.83 0.0261 16 428 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.924 0.82 – 1.04 0.194 282 4758 exclusion phecode
782.3 Edema Symptoms 1.08 0.918 – 1.27 0.356 148 4098 exclusion phecode
782.6 Pallor and flushing Symptoms 1.28 0.878 – 1.85 0.201 27 431 exclusion phecode
783 Fever of unknown origin Symptoms 0.989 0.912 – 1.07 0.782 651 10025 exclusion phecode
785 Abdominal pain Symptoms 0.99 0.967 – 1.01 0.386 8153 79337 exclusion phecode
788 Syncope and collapse Symptoms 0.962 0.914 – 1.01 0.141 1561 22542 exclusion phecode
789 Nausea and vomiting Symptoms 1.04 0.991 – 1.09 0.108 1740 29399 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 0.874 0.556 – 1.38 0.562 22 363 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.03 0.607 – 1.76 0.901 12 225 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 0.973 0.919 – 1.03 0.35 1275 15922 exclusion phecode
791 Gangrene Symptoms 0.812 0.633 – 1.04 0.102 59 1331 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1.03 0.629 – 1.69 0.904 16 230 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.43 0.885 – 2.32 0.144 19 351 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.05 0.867 – 1.28 0.609 109 1383 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.767 0.568 – 1.04 0.0837 45 328 exclusion phecode
797 Shock Symptoms 1.5 0.898 – 2.51 0.122 11 391 exclusion phecode
797.1 Cardiogenic shock Symptoms 3.94 1.37 – 11.3 0.011 3 255 exclusion phecode
798 Malaise and fatigue Symptoms 0.94 0.861 – 1.03 0.166 527 8785 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 0.876 0.731 – 1.05 0.155 117 1671 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1 0.949 – 1.06 0.947 1422 17634 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.946 0.847 – 1.06 0.331 329 4441 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.21 0.817 – 1.8 0.339 24 399 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.01 0.921 – 1.11 0.784 468 5497 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 1.22 1.04 – 1.44 0.0163 163 1946 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.06 0.968 – 1.16 0.205 506 5615 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.06 0.964 – 1.17 0.225 439 4704 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.06 0.899 – 1.26 0.48 151 1882 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 1.04 0.99 – 1.09 0.123 1818 20913 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1.02 0.906 – 1.15 0.76 308 4192 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.04 0.982 – 1.11 0.172 1191 13196 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.04 0.928 – 1.16 0.521 344 3979 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 1.05 0.972 – 1.13 0.22 742 8448 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.975 0.855 – 1.11 0.705 236 3560 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.07 0.911 – 1.25 0.416 156 1968 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.884 0.779 – 1 0.0555 256 3335 exclusion phecode
817 Concussion Injuries & Poisonings 1.05 0.81 – 1.36 0.708 63 593 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.01 0.791 – 1.28 0.967 66 1256 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.15 1.05 – 1.26 0.00208 505 7248 exclusion phecode
823 Torus fracture Injuries & Poisonings 1.03 0.924 – 1.14 0.617 377 4275 exclusion phecode
830 Dislocation Injuries & Poisonings 1.06 0.962 – 1.17 0.237 443 5155 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 1.05 1.01 – 1.08 0.013 3460 39215 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.927 0.748 – 1.15 0.488 89 1413 exclusion phecode
840 Sprains and strains Injuries & Poisonings 1.16 0.947 – 1.41 0.154 106 1188 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.99 0.928 – 1.06 0.749 979 13517 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.03 0.663 – 1.61 0.885 19 419 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 0.996 0.782 – 1.27 0.976 68 1353 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.1 0.967 – 1.26 0.146 233 4551 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.958 0.836 – 1.1 0.542 237 3304 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.03 0.951 – 1.12 0.434 611 7863 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.06 0.968 – 1.15 0.215 533 8246 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.13 0.596 – 2.13 0.712 10 174 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.06 0.97 – 1.16 0.199 512 8680 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.24 0.901 – 1.72 0.185 37 684 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 0.946 0.65 – 1.38 0.77 27 483 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.03 0.937 – 1.14 0.519 427 7159 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.08 0.768 – 1.51 0.666 34 530 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 1.13 0.653 – 1.95 0.664 11 155 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.04 0.963 – 1.11 0.345 785 10354 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.685 0.316 – 1.49 0.338 6 116 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.77 0.446 – 1.33 0.347 11 226 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.32 0.941 – 1.85 0.108 36 417 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 0.896 0.726 – 1.11 0.306 91 1187 exclusion phecode
873 Broken tooth Injuries & Poisonings 0.856 0.654 – 1.12 0.257 56 590 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 0.442 0.267 – 0.731 0.00148 15 435 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.11 0.758 – 1.63 0.591 26 409 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.1 0.968 – 1.24 0.146 270 3320 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.05 0.966 – 1.13 0.274 662 10580 exclusion phecode
916 Contusion Injuries & Poisonings 1.03 0.897 – 1.18 0.704 220 3503 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 1.01 0.724 – 1.42 0.942 36 461 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.02 0.834 – 1.25 0.841 94 930 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.948 0.74 – 1.21 0.669 70 580 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.12 1.02 – 1.24 0.021 415 5310 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.27 0.952 – 1.68 0.105 45 568 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.755 0.427 – 1.33 0.334 10 249 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.09 0.902 – 1.31 0.382 115 1379 exclusion phecode
947 Urticaria Injuries & Poisonings 0.998 0.795 – 1.25 0.987 72 995 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.08 0.861 – 1.35 0.505 82 1052 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.91 0.728 – 1.14 0.406 81 1089 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.28 0.952 – 1.71 0.103 47 656 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.913 0.718 – 1.16 0.459 66 1222 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 0.89 0.433 – 1.83 0.751 10 131 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.19 0.688 – 2.06 0.535 11 197 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.985 0.953 – 1.02 0.386 3803 47343 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.992 0.958 – 1.03 0.675 3301 41458 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.12 0.916 – 1.36 0.274 105 1054 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.954 0.825 – 1.1 0.529 203 2332 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.09 0.826 – 1.43 0.555 53 935 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.06 0.804 – 1.39 0.699 53 902 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.05 0.717 – 1.53 0.809 27 563 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.935 0.686 – 1.27 0.671 38 728 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.939 0.688 – 1.28 0.691 37 709 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1 0.938 – 1.07 0.971 976 15764 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.898 0.781 – 1.03 0.131 212 3010 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.912 0.677 – 1.23 0.542 44 1293 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.12 0.833 – 1.49 0.462 46 1023 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.671 0.499 – 0.904 0.00867 44 1315 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.05 0.865 – 1.27 0.639 110 1491 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.07 0.913 – 1.25 0.414 169 5052 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.54 0.986 – 2.4 0.0578 20 485 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.83 0.564 – 1.22 0.342 21 733 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 3.27 1.24 – 8.6 0.0164 3 227 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.48 0.834 – 2.62 0.181 10 298 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.978 0.502 – 1.91 0.949 5 245 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.618 0.32 – 1.19 0.153 9 149 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.32 0.611 – 2.83 0.484 4 142 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.24 0.901 – 1.7 0.189 41 635 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.08 0.884 – 1.32 0.445 96 1841 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.679 0.436 – 1.06 0.0873 19 515 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 0.421 0.187 – 0.95 0.0372 9 147 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.06 0.563 – 1.98 0.865 9 258 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 1.17 0.772 – 1.78 0.456 24 282 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.78 0.456 – 1.34 0.365 10 229 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.17 1.07 – 1.29 0.000927 469 7684 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 0.986 0.877 – 1.11 0.82 284 7570 exclusion phecode
994.2 Sepsis Injuries & Poisonings 0.986 0.877 – 1.11 0.82 284 7570 exclusion phecode
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