Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Body mass index Michigan Genomics Initiative Freeze 3 (MGI) PheWAS analysis

Body mass index — Michigan Genomics Initiative Freeze 3 (MGI) PRS PheWAS

PRS model
PRS ID exprsweb-bmi-21001-irnt-pt-mgi-freeze3-20211120Legacy PTC+T (DS)UK Biobank GWAS

Evaluation cohort: Michigan Genomics Initiative Freeze 3 (MGI).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: normal-range subset (18.5-24.9).

For this ExPRS, the exclusion sensitivity scan keeps only the study's normal-range subset for Body mass index (18.5-24.9) before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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732 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.02 0.984 – 1.07 0.245 3004 29292 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.11 1.05 – 1.18 0.000608 1322 13162 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.11 1.04 – 1.19 0.00211 1046 10455 all phecode
008.6 Viral Enteritis Infectious Diseases 1.1 1.02 – 1.19 0.0151 770 7676 all phecode
010 Tuberculosis Infectious Diseases 1.1 0.956 – 1.26 0.183 244 2425 all phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.948 0.753 – 1.19 0.646 86 855 all phecode
038 Septicemia Infectious Diseases 1.13 1.09 – 1.18 9.88e-09 2582 24779 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.13 1.03 – 1.24 0.00784 568 5629 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.2 1.04 – 1.38 0.0111 235 2350 all phecode
038.3 Bacteremia Infectious Diseases 1.16 1.09 – 1.23 3.75e-06 1210 12079 all phecode
041 Bacterial infection NOS Infectious Diseases 1.09 1.06 – 1.12 1.77e-08 5750 38799 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.17 1.11 – 1.23 4.2e-09 1707 16977 all phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.2 1.11 – 1.28 6.68e-07 920 9192 all phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.2 1.11 – 1.3 3.06e-06 783 7812 all phecode
041.2 Streptococcus infection Infectious Diseases 1.1 1.04 – 1.16 0.000456 1632 16287 all phecode
041.21 Rheumatic fever / chorea Infectious Diseases 0.992 0.867 – 1.13 0.905 257 2554 all phecode
041.4 E. coli Infectious Diseases 1.1 1.03 – 1.17 0.00279 1175 11680 all phecode
041.8 H. pylori Infectious Diseases 1.03 0.899 – 1.18 0.674 257 2521 all phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.2 1.08 – 1.34 0.00119 387 3864 all phecode
053 Herpes zoster Infectious Diseases 0.944 0.894 – 0.998 0.0411 1560 15184 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.883 0.762 – 1.02 0.0965 220 2169 all phecode
054 Herpes simplex Infectious Diseases 0.936 0.886 – 0.988 0.0174 1593 15600 all phecode
070 Viral hepatitis Infectious Diseases 1.07 0.993 – 1.16 0.0738 829 8280 all phecode
070.1 Viral hepatitis A Infectious Diseases 1.11 0.88 – 1.4 0.379 87 860 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.07 0.925 – 1.24 0.354 215 2138 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.08 0.983 – 1.19 0.11 528 5280 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.09 0.93 – 1.27 0.294 197 1964 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.02 0.952 – 1.08 0.644 1145 11381 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.09 0.914 – 1.29 0.35 145 1450 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.03 0.852 – 1.25 0.758 117 1163 all phecode
078 Viral warts & HPV Infectious Diseases 0.921 0.887 – 0.956 1.54e-05 3434 29624 all phecode
079 Viral infection Infectious Diseases 0.961 0.934 – 0.988 0.00462 6664 35342 all phecode
079.1 Varicella infection Infectious Diseases 0.9 0.869 – 0.933 8.48e-09 3793 31251 all phecode
079.2 Infectious mononucleosis Infectious Diseases 0.877 0.771 – 0.998 0.0462 283 2723 all phecode
079.9 Viremia, NOS Infectious Diseases 1.07 0.99 – 1.15 0.0901 838 8253 all phecode
080 Postoperative infection Infectious Diseases 1.15 1.1 – 1.2 7.05e-11 2619 26065 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.12 1.06 – 1.18 3.36e-05 1589 15884 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.998 0.932 – 1.07 0.964 965 9630 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.01 0.973 – 1.05 0.601 3544 30054 all phecode
110.1 Dermatophytosis Infectious Diseases 1.02 0.98 – 1.06 0.341 3241 27244 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.04 0.992 – 1.1 0.0982 2044 16765 all phecode
110.12 Althete's foot Infectious Diseases 1.04 0.966 – 1.12 0.309 899 8043 all phecode
110.13 Dermatophytosis of the body Infectious Diseases 1.04 0.959 – 1.12 0.373 790 7827 all phecode
110.2 Dermatomycoses Infectious Diseases 0.947 0.85 – 1.05 0.318 398 3971 all phecode
112 Candidiasis Infectious Diseases 1.11 1.07 – 1.15 7.05e-09 3685 30495 all phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.28 1.17 – 1.39 1.51e-08 682 6732 all phecode
117 Mycoses Infectious Diseases 1.02 0.932 – 1.11 0.713 608 6069 all phecode
117.1 Histoplasmosis Infectious Diseases 1.06 0.839 – 1.34 0.621 81 801 all phecode
117.4 Aspergillosis Infectious Diseases 1.05 0.874 – 1.25 0.622 140 1387 all phecode
130 Spirochetal infection Infectious Diseases 0.895 0.762 – 1.05 0.174 168 1677 all phecode
130.1 Lyme disease Infectious Diseases 0.885 0.73 – 1.07 0.212 116 1160 all phecode
131 Protozoan infection Infectious Diseases 1.34 1.03 – 1.73 0.0272 61 610 all phecode
132 Infestation (lice, mites) Infectious Diseases 1.12 0.964 – 1.3 0.139 195 1948 all phecode
134 Helminthiases Infectious Diseases 0.982 0.779 – 1.24 0.875 83 812 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.14 0.85 – 1.54 0.375 53 513 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.04 1.01 – 1.08 0.0253 3279 32486 all phecode
145 Cancer of mouth Neoplasms 1.02 0.961 – 1.07 0.573 1481 14725 all phecode
145.1 Cancer of lip Neoplasms 0.98 0.77 – 1.25 0.866 76 750 all phecode
145.2 Cancer of tongue Neoplasms 1.01 0.926 – 1.1 0.846 645 6430 all phecode
145.3 Cancer of major salivary glands Neoplasms 0.968 0.865 – 1.08 0.579 361 3597 all phecode
145.4 Cancer of the gums Neoplasms 1.02 0.861 – 1.21 0.823 166 1632 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.05 0.905 – 1.22 0.528 206 2048 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.02 0.961 – 1.08 0.519 1290 12873 all phecode
149.1 Cancer of oropharynx Neoplasms 0.996 0.889 – 1.12 0.945 350 3499 all phecode
149.2 Cancer of nasopharynx Neoplasms 1.11 0.897 – 1.37 0.338 100 1000 all phecode
149.3 Cancer of hypopharynx Neoplasms 1.03 0.805 – 1.32 0.819 82 819 all phecode
149.4 Cancer of larynx Neoplasms 1.14 1.02 – 1.27 0.0186 386 3857 all phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 1.01 0.92 – 1.1 0.863 552 5505 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.928 0.807 – 1.07 0.292 240 2398 all phecode
150 Cancer of esophagus Neoplasms 1.27 1.14 – 1.4 6.6e-06 433 4315 all phecode
151 Cancer of stomach Neoplasms 1.11 1 – 1.22 0.0417 498 4962 all phecode
153 Colorectal cancer Neoplasms 0.992 0.937 – 1.05 0.796 1458 14383 all phecode
153.2 Colon cancer Neoplasms 1 0.942 – 1.07 0.885 1160 11472 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.986 0.913 – 1.06 0.711 815 8093 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.08 0.979 – 1.19 0.126 511 5097 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.13 1.01 – 1.27 0.0308 344 3433 all phecode
157 Pancreatic cancer Neoplasms 1.03 0.936 – 1.13 0.551 503 5005 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.02 0.97 – 1.08 0.39 1623 15759 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.05 0.995 – 1.1 0.0786 1818 17869 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.08 0.934 – 1.25 0.298 221 2206 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.02 0.866 – 1.21 0.787 158 1578 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.03 0.908 – 1.17 0.625 293 2920 all phecode
164 Cancer of intrathoracic organs Neoplasms 0.956 0.796 – 1.15 0.628 133 1324 all phecode
165 Cancer within the respiratory system Neoplasms 1.07 1.01 – 1.13 0.0325 1336 13340 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.06 0.99 – 1.13 0.0935 1057 10552 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.98 0.931 – 1.03 0.43 1792 17850 all phecode
170.1 Bone cancer Neoplasms 0.966 0.895 – 1.04 0.385 773 7690 all phecode
170.2 Cancer of connective tissue Neoplasms 0.98 0.922 – 1.04 0.503 1266 12632 all phecode
172 Skin cancer Neoplasms 0.939 0.915 – 0.964 2.28e-06 8608 33186 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.92 0.891 – 0.949 1.78e-07 5330 30106 all phecode
172.11 Melanomas of skin Neoplasms 0.921 0.885 – 0.958 3.98e-05 3100 25064 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.933 0.907 – 0.96 1.49e-06 7095 30462 all phecode
172.21 Basal cell carcinoma Neoplasms 0.907 0.874 – 0.941 2.44e-07 3690 23868 all phecode
172.22 Squamous cell carcinoma Neoplasms 0.961 0.919 – 1.01 0.0885 2414 17683 all phecode
172.3 Carcinoma in situ of skin Neoplasms 0.878 0.829 – 0.93 8.74e-06 1482 12326 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.915 0.872 – 0.961 0.000372 1997 18755 all phecode
174 Breast cancer Neoplasms 0.923 0.886 – 0.962 0.000154 3186 15514 all phecode
174.1 Breast cancer [female] Neoplasms 0.918 0.88 – 0.958 8.17e-05 3036 14701 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.922 0.883 – 0.962 0.000168 2991 14639 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.814 0.706 – 0.939 0.00485 233 2307 all phecode
175 Acquired absence of breast Neoplasms 0.961 0.893 – 1.03 0.289 919 8920 all phecode
180 Cervical cancer and dysplasia Neoplasms 1.02 0.959 – 1.08 0.578 1431 12185 all phecode
180.1 Cervical cancer Neoplasms 1.11 1.01 – 1.22 0.0382 500 4982 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.974 0.911 – 1.04 0.444 1048 9323 all phecode
182 Malignant neoplasm of uterus Neoplasms 1.12 1.03 – 1.21 0.00531 765 7613 all phecode
184 Cancer of other female genital organs Neoplasms 1.01 0.945 – 1.07 0.834 1191 11592 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.972 0.887 – 1.07 0.543 573 5719 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.945 0.851 – 1.05 0.289 432 4309 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.04 0.953 – 1.14 0.376 608 6057 all phecode
185 Cancer of prostate Neoplasms 0.942 0.9 – 0.985 0.00904 2901 10342 all phecode
187 Cancer of other male genital organs Neoplasms 0.948 0.845 – 1.06 0.368 339 3384 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.07 0.88 – 1.31 0.481 115 1141 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.915 0.784 – 1.07 0.26 183 1830 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.879 0.657 – 1.18 0.383 57 562 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.1 1.05 – 1.14 9.06e-06 2923 23541 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.1 1.04 – 1.17 0.000878 1450 14437 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.12 1.06 – 1.19 0.000198 1267 12655 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.07 0.928 – 1.23 0.358 237 2347 all phecode
189.2 Cancer of bladder Neoplasms 1.08 1.03 – 1.14 0.0029 1783 15224 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.08 1.02 – 1.14 0.00458 1657 14178 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.08 0.996 – 1.18 0.0605 678 6586 all phecode
190 Cancer of eye Neoplasms 0.829 0.69 – 0.998 0.0471 138 1374 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.985 0.923 – 1.05 0.65 1078 10771 all phecode
191.1 Cancer of brain and nervous system Neoplasms 0.975 0.901 – 1.06 0.54 706 7052 all phecode
191.11 Cancer of brain Neoplasms 0.959 0.879 – 1.05 0.344 600 5996 all phecode
193 Thyroid cancer Neoplasms 1.02 0.955 – 1.1 0.503 945 9393 all phecode
194 Cancer of other endocrine glands Neoplasms 1.02 0.936 – 1.12 0.606 579 5759 all phecode
195 Cancer, suspected or other Neoplasms 1.01 0.984 – 1.03 0.596 16962 26401 all phecode
195.1 Malignant neoplasm, other Neoplasms 1 0.981 – 1.02 0.831 16670 26384 all phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1.02 0.953 – 1.09 0.613 1103 9766 all phecode
196 Radiotherapy Neoplasms 0.923 0.882 – 0.965 0.000473 2427 17006 all phecode
197 Chemotherapy Neoplasms 1.01 0.978 – 1.04 0.537 4952 23797 all phecode
198 Secondary malignant neoplasm Neoplasms 1.02 0.989 – 1.05 0.196 5801 23481 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.999 0.963 – 1.04 0.965 3677 21489 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.06 0.996 – 1.14 0.0669 1072 10334 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.05 0.976 – 1.13 0.188 866 8538 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.03 0.955 – 1.12 0.422 767 7558 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.02 0.933 – 1.11 0.71 640 6338 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.01 0.936 – 1.08 0.86 866 8307 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.961 0.854 – 1.08 0.508 336 3253 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.01 0.977 – 1.04 0.613 5693 25767 all phecode
199.4 Neurofibromatosis Neoplasms 1.03 0.825 – 1.28 0.817 88 880 all phecode
200 Myeloproliferative disease Neoplasms 1.09 1.02 – 1.16 0.0137 1113 11098 all phecode
200.1 Polycythemia vera Neoplasms 1.22 1.06 – 1.41 0.00596 231 2310 all phecode
201 Hodgkin's disease Neoplasms 1.18 1 – 1.39 0.0453 172 1705 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.02 0.97 – 1.08 0.389 1559 15571 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.02 0.962 – 1.08 0.501 1329 13268 all phecode
202.21 Nodular lymphoma Neoplasms 0.959 0.883 – 1.04 0.317 693 6923 all phecode
202.22 Reticulosarcoma Neoplasms 1.2 1.02 – 1.42 0.0303 170 1693 all phecode
202.24 Large cell lymphoma Neoplasms 1.07 0.906 – 1.27 0.411 160 1586 all phecode
204 Leukemia Neoplasms 1.05 0.969 – 1.14 0.227 689 6876 all phecode
204.1 Lymphoid leukemia Neoplasms 0.889 0.772 – 1.02 0.103 236 2354 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.821 0.641 – 1.05 0.12 74 734 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.876 0.74 – 1.04 0.126 173 1724 all phecode
204.2 Myeloid leukemia Neoplasms 1.14 0.998 – 1.31 0.0532 265 2633 all phecode
204.21 Myeloid leukemia, acute Neoplasms 1.22 1.02 – 1.46 0.0264 153 1516 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.09 0.813 – 1.46 0.563 61 610 all phecode
204.4 Multiple myeloma Neoplasms 1.18 1.02 – 1.36 0.0284 217 2162 all phecode
208 Benign neoplasm of colon Neoplasms 0.997 0.974 – 1.02 0.793 10303 34953 all phecode
209 Neuroendocrine tumors Neoplasms 1.06 0.929 – 1.22 0.371 258 2580 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.987 0.939 – 1.04 0.593 1891 18839 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.09 1.06 – 1.12 5.07e-11 7329 36606 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.06 1.01 – 1.11 0.0297 1843 18412 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1 0.948 – 1.05 0.987 1677 15527 all phecode
214 Lipoma Neoplasms 0.984 0.929 – 1.04 0.584 1437 14132 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.953 0.885 – 1.03 0.203 883 8710 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.01 0.977 – 1.04 0.562 4528 39509 all phecode
216 Benign neoplasm of skin Neoplasms 0.934 0.913 – 0.955 2.43e-09 11528 34919 all phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 0.879 0.744 – 1.04 0.129 174 1701 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.845 0.803 – 0.89 2e-10 1786 17184 all phecode
217.1 Nevus, non-neoplastic Neoplasms 0.848 0.804 – 0.894 1.29e-09 1679 16116 all phecode
218 Benign neoplasm of uterus Neoplasms 0.989 0.955 – 1.03 0.562 4301 16661 all phecode
218.1 Uterine leiomyoma Neoplasms 0.952 0.904 – 1 0.0645 1835 15733 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.995 0.957 – 1.03 0.797 3403 16447 all phecode
220 Benign neoplasm of ovary Neoplasms 1.03 0.956 – 1.11 0.459 893 8783 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.01 0.963 – 1.06 0.646 2042 14248 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.911 0.855 – 0.971 0.00431 1133 10663 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.07 1.01 – 1.12 0.0184 1801 12657 all phecode
224 Benign neoplasm of eye Neoplasms 0.95 0.874 – 1.03 0.23 691 6752 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.921 0.842 – 1.01 0.0705 595 5773 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.03 0.971 – 1.1 0.296 1209 12074 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.02 0.947 – 1.09 0.664 947 9454 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.05 0.927 – 1.2 0.429 289 2890 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.01 0.953 – 1.07 0.709 1329 13264 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.01 0.956 – 1.06 0.785 1690 16896 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.17 1.06 – 1.29 0.00184 467 4644 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.905 0.838 – 0.978 0.0114 795 7941 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.03 0.925 – 1.14 0.63 435 4350 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.855 0.815 – 0.896 6.7e-11 2149 20946 all phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.827 0.779 – 0.878 4.46e-10 1356 13336 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.998 0.972 – 1.02 0.861 7767 36615 all phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.985 0.956 – 1.01 0.3 5743 34218 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.01 0.947 – 1.08 0.705 1031 9761 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.05 1 – 1.09 0.0293 2910 22227 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.04 0.995 – 1.09 0.0842 2265 19902 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.07 1.01 – 1.14 0.0197 1304 12479 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.06 1 – 1.12 0.0456 1400 13425 all phecode
242.1 Graves' disease Endocrine/metabolic 1.09 0.988 – 1.2 0.0886 515 5068 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.16 0.952 – 1.41 0.142 124 1224 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.03 0.907 – 1.17 0.667 292 2898 all phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 1.11 0.923 – 1.33 0.271 144 1432 all phecode
244 Hypothyroidism Endocrine/metabolic 1.07 1.04 – 1.09 3.13e-06 8099 32717 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.01 0.964 – 1.07 0.574 1762 17230 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.07 1.01 – 1.14 0.0244 1261 11982 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.07 1.04 – 1.1 3.51e-06 7542 32208 all phecode
245 Thyroiditis Endocrine/metabolic 1.11 1.03 – 1.2 0.00603 832 7882 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.11 1.02 – 1.21 0.0134 686 6517 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.1 1.02 – 1.2 0.0207 679 6449 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.05 1.02 – 1.08 0.00299 6129 30240 all phecode
246.2 Thyroid cyst Endocrine/metabolic 0.88 0.711 – 1.09 0.242 101 960 all phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1.04 0.97 – 1.12 0.255 886 8696 all phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.39 1.29 – 1.49 3.4e-18 1150 8340 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.27 1.24 – 1.3 3.27e-91 13947 31815 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.33 1.25 – 1.41 2.63e-19 2364 11758 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.12 0.938 – 1.34 0.209 262 960 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.2 1.06 – 1.36 0.00307 551 2686 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.28 1.14 – 1.44 1.89e-05 784 3018 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.27 1.13 – 1.44 9.6e-05 638 2675 all phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 1.08 0.885 – 1.32 0.447 155 850 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.38 1.35 – 1.42 6.82e-123 9843 29688 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.38 1.17 – 1.62 9.37e-05 282 1327 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.54 1.45 – 1.63 2.14e-46 1941 13510 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.43 1.34 – 1.54 7.26e-25 1643 9668 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.54 1.46 – 1.63 1.28e-58 2557 16502 all phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.52 1.39 – 1.65 5.92e-21 860 6143 all phecode
250.3 Insulin pump user Endocrine/metabolic 1.46 1.39 – 1.53 1.13e-57 3496 20809 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.16 1.13 – 1.19 4.76e-25 8385 30645 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.1 1.04 – 1.16 0.000503 1870 15861 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.17 1.13 – 1.2 5.75e-25 7553 30071 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.19 0.972 – 1.45 0.093 136 1067 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.55 1.46 – 1.65 3.8e-48 2132 13390 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.22 1.15 – 1.3 1.02e-11 1691 10517 all phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.11 1.03 – 1.19 0.00449 991 8469 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.22 1.13 – 1.31 1.07e-07 1207 8570 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.06 1.01 – 1.11 0.0125 2282 22119 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.05 1 – 1.1 0.0377 2088 20335 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.01 0.915 – 1.11 0.874 508 5073 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.982 0.912 – 1.06 0.625 859 8544 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.03 0.903 – 1.18 0.653 263 2621 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.09 0.866 – 1.38 0.459 83 826 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.991 0.861 – 1.14 0.896 226 2250 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.02 0.813 – 1.29 0.844 86 860 all phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 1.03 0.845 – 1.25 0.791 121 1209 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.943 0.769 – 1.16 0.574 108 1080 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.12 1.06 – 1.19 5.12e-05 1506 14869 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.999 0.894 – 1.12 0.99 373 3730 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.02 0.873 – 1.2 0.785 183 1830 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1 0.832 – 1.2 0.998 135 1350 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.06 0.969 – 1.15 0.209 626 6239 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.07 0.975 – 1.16 0.165 596 5941 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.14 1.07 – 1.22 6.08e-05 1146 10513 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.26 1.17 – 1.37 1.34e-08 742 7128 all phecode
257 Testicular dysfunction Endocrine/metabolic 1 0.936 – 1.07 0.967 1015 9238 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.997 0.931 – 1.07 0.939 983 8933 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.24 0.995 – 1.55 0.0555 91 910 all phecode
258.1 Postablative ovarian failure Endocrine/metabolic 1.05 0.855 – 1.3 0.621 109 1090 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.06 0.989 – 1.13 0.104 1038 10259 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.06 1.01 – 1.1 0.0084 2880 26812 all phecode
260.1 Cachexia Endocrine/metabolic 1.01 0.886 – 1.14 0.925 292 2911 all phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.08 1.02 – 1.14 0.00419 1691 16847 all phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.08 0.985 – 1.17 0.106 614 6140 all phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.06 0.971 – 1.15 0.193 629 6236 all phecode
260.6 Anorexia Endocrine/metabolic 1.04 0.967 – 1.12 0.291 868 8591 all phecode
260.7 Polyphagia Endocrine/metabolic 1.13 0.862 – 1.47 0.382 65 643 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.13 1.1 – 1.16 1.32e-19 7718 35203 all phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1.18 0.902 – 1.54 0.227 69 690 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.25 1.16 – 1.35 7.23e-09 857 8405 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.13 1.1 – 1.16 2.08e-18 7255 35225 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.906 0.681 – 1.21 0.497 52 511 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.19 1.12 – 1.27 1.03e-07 1182 11676 all phecode
263 Other nutritional deficiency Endocrine/metabolic 1.08 1.03 – 1.14 0.0033 1651 15788 all phecode
264 Lack of normal physiological development Endocrine/metabolic 0.995 0.867 – 1.14 0.949 239 2301 all phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 0.992 0.818 – 1.2 0.932 122 1220 all phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 0.98 0.775 – 1.24 0.866 81 772 all phecode
269 Proteinuria Endocrine/metabolic 1.17 1.11 – 1.24 5.21e-09 1694 13981 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.05 0.983 – 1.13 0.139 967 9575 all phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.923 0.778 – 1.09 0.358 170 1697 all phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.936 0.775 – 1.13 0.487 134 1334 all phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 1.17 0.944 – 1.46 0.15 96 954 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.05 0.972 – 1.14 0.206 737 7303 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.1 0.981 – 1.23 0.104 384 3781 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.02 0.791 – 1.31 0.892 71 695 all phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 0.804 0.616 – 1.05 0.109 69 690 all phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.07 0.95 – 1.22 0.254 299 2984 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.02 0.981 – 1.06 0.313 2907 28132 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.02 0.977 – 1.06 0.396 2827 27425 all phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.06 0.861 – 1.31 0.576 102 1007 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.11 1.08 – 1.13 1.22e-19 18881 26670 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.11 1.08 – 1.13 1.23e-19 18843 26654 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.07 1.04 – 1.11 1.4e-05 5928 21600 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.15 1.08 – 1.22 7.77e-06 1360 11837 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.13 1.09 – 1.18 2.12e-09 3538 18449 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.03 0.909 – 1.16 0.658 313 3011 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.19 1.14 – 1.24 1.48e-14 2524 22729 all phecode
274.1 Gout Endocrine/metabolic 1.19 1.14 – 1.25 4.74e-15 2409 21991 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.18 1.1 – 1.26 9.02e-07 1082 10576 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.04 0.889 – 1.22 0.611 195 1890 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.02 0.869 – 1.2 0.789 183 1772 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.08 1.04 – 1.11 7.9e-06 4357 37091 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.949 0.819 – 1.1 0.486 218 2180 all phecode
275.11 Hereditary hemochromatosis Hematopoietic 0.938 0.755 – 1.17 0.564 99 990 all phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 1.05 0.8 – 1.37 0.738 62 614 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.2 1.13 – 1.28 1.95e-08 1154 11504 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.07 1.03 – 1.11 0.000777 3369 31544 all phecode
275.51 Hypocalcemia Endocrine/metabolic 1.02 0.948 – 1.1 0.608 898 8969 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.1 1.04 – 1.17 0.00136 1366 13634 all phecode
275.6 Hypercalcemia Endocrine/metabolic 1.06 0.999 – 1.12 0.0552 1468 14183 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.12 1.09 – 1.15 1.38e-19 9238 37046 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.13 1.09 – 1.16 6.65e-16 6352 34366 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.21 1.1 – 1.33 6.78e-05 550 5434 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.11 1.06 – 1.15 6.23e-06 2514 23219 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.17 1.12 – 1.22 2.04e-14 2992 25216 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.11 1.06 – 1.16 2.48e-05 2148 20909 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.17 1.11 – 1.23 1.01e-10 2086 20332 all phecode
276.41 Acidosis Endocrine/metabolic 1.16 1.1 – 1.22 9.79e-09 1788 17572 all phecode
276.42 Alkalosis Endocrine/metabolic 1.22 1.1 – 1.34 8.59e-05 476 4741 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.13 1.09 – 1.17 4.18e-13 4574 34527 all phecode
276.6 Fluid overload Endocrine/metabolic 1.28 1.21 – 1.36 3.19e-16 1384 13211 all phecode
276.8 Polydipsia Endocrine/metabolic 0.843 0.698 – 1.02 0.077 124 1240 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.13 1.09 – 1.17 5.27e-12 4112 35070 all phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.42 1.27 – 1.58 1.96e-10 403 3991 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.937 0.865 – 1.02 0.114 720 7161 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.07 0.997 – 1.15 0.0615 936 9270 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.12 1.03 – 1.21 0.00577 773 7668 all phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.33 1.24 – 1.44 1.97e-14 916 8359 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.57 1.54 – 1.6 4.88e-398 19419 27331 all phecode
278.1 Obesity Endocrine/metabolic 1.67 1.63 – 1.7 9.01e-458 17129 27321 all phecode
278.11 Morbid obesity Endocrine/metabolic 1.95 1.89 – 2 1.16e-450 8280 27172 all phecode
278.3 Localized adiposity Endocrine/metabolic 1.69 1.49 – 1.91 6.63e-17 324 3228 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.42 1.35 – 1.49 2.73e-43 2104 17411 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.04 1 – 1.09 0.0337 2934 28612 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1.01 0.952 – 1.08 0.672 1161 11571 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.96 0.852 – 1.08 0.5 330 3278 all phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 1.01 0.934 – 1.1 0.78 754 7516 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.01 0.974 – 1.04 0.743 4885 36552 all phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 0.994 0.91 – 1.09 0.903 601 5988 all phecode
280 Iron deficiency anemias Hematopoietic 1.12 1.08 – 1.16 2.66e-11 4626 30873 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.12 1.08 – 1.16 6.34e-11 4484 30649 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.1 1.04 – 1.16 0.000417 1771 17196 all phecode
281 Other deficiency anemia Hematopoietic 1.05 0.951 – 1.15 0.353 519 5120 all phecode
281.1 Megaloblastic anemia Hematopoietic 0.994 0.867 – 1.14 0.934 253 2497 all phecode
281.11 Pernicious anemia Hematopoietic 1.08 0.878 – 1.32 0.479 114 1108 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.964 0.823 – 1.13 0.645 187 1817 all phecode
281.9 Deficiency anemias Hematopoietic 1.06 0.929 – 1.2 0.399 285 2830 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.09 0.967 – 1.24 0.154 323 3188 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.07 0.924 – 1.25 0.351 216 2113 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.18 1.01 – 1.38 0.0417 192 1920 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.15 0.963 – 1.37 0.123 155 1550 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.27 0.957 – 1.68 0.0983 64 633 all phecode
284 Aplastic anemia Hematopoietic 1.06 0.98 – 1.15 0.144 697 6943 all phecode
284.1 Pancytopenia Hematopoietic 1.07 0.977 – 1.16 0.151 612 6100 all phecode
285 Other anemias Hematopoietic 1.09 1.06 – 1.11 1.51e-13 11794 33591 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.11 1.06 – 1.15 1.93e-07 3325 27709 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.14 1.08 – 1.19 1.28e-07 2055 19939 all phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.23 1.14 – 1.32 1.91e-08 932 9106 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.05 0.962 – 1.14 0.298 690 6892 all phecode
286 Coagulation defects Hematopoietic 1.1 1.06 – 1.14 6.85e-08 3844 33384 all phecode
286.1 Congenital coagulation defects Hematopoietic 1.04 0.91 – 1.2 0.543 250 2466 all phecode
286.11 Von willebrand's disease Hematopoietic 1.14 0.91 – 1.43 0.257 83 822 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.99 0.819 – 1.2 0.919 126 1260 all phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.12 1.07 – 1.16 1.95e-08 3354 25918 all phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 0.912 0.726 – 1.15 0.432 97 962 all phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 1.18 1.03 – 1.36 0.0149 254 2529 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.1 0.915 – 1.31 0.321 132 1294 all phecode
286.6 Defibrination syndrome Hematopoietic 1.1 1.05 – 1.15 1.31e-05 2579 25377 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.1 1.06 – 1.14 2.48e-06 3014 29294 all phecode
286.8 Hypercoagulable state Hematopoietic 1.09 1.01 – 1.17 0.0318 846 8437 all phecode
286.81 Primary hypercoagulable state Hematopoietic 1.07 0.995 – 1.16 0.0679 813 8111 all phecode
286.9 Abnormal coagulation profile Hematopoietic 1.14 1.07 – 1.22 3.09e-05 1182 11487 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.06 1.02 – 1.11 0.00131 3288 28474 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.02 0.88 – 1.18 0.811 211 2094 all phecode
287.3 Thrombocytopenia Hematopoietic 1.06 1.02 – 1.1 0.00695 2938 26323 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.07 0.982 – 1.17 0.119 601 5994 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.02 0.932 – 1.12 0.659 569 5686 all phecode
287.4 Qualitative platelet defects Hematopoietic 1.22 0.996 – 1.48 0.0547 112 1120 all phecode
288 Diseases of white blood cells Hematopoietic 1.08 1.04 – 1.11 6.5e-06 4886 36527 all phecode
288.1 Decreased white blood cell count Hematopoietic 1 0.949 – 1.06 0.964 1599 15951 all phecode
288.11 Neutropenia Hematopoietic 1.01 0.946 – 1.08 0.787 1106 11041 all phecode
288.2 Elevated white blood cell count Hematopoietic 1.09 1.05 – 1.13 4.84e-07 4082 35079 all phecode
288.3 Eosinophilia Hematopoietic 0.868 0.74 – 1.02 0.0801 187 1866 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.03 0.981 – 1.09 0.217 1757 17434 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.01 0.941 – 1.09 0.76 918 9087 all phecode
289.4 Lymphadenitis Hematopoietic 1.06 1.02 – 1.1 0.0014 3888 34715 all phecode
289.5 Diseases of spleen Hematopoietic 1.03 0.921 – 1.14 0.638 393 3913 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.11 0.974 – 1.27 0.116 255 2550 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.11 0.992 – 1.24 0.0693 385 3813 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.03 0.971 – 1.1 0.31 1318 11547 all phecode
290.1 Dementias Mental Disorders 1.02 0.925 – 1.12 0.74 541 4910 all phecode
290.11 Alzheimer's disease Mental Disorders 1.02 0.849 – 1.22 0.857 151 1389 all phecode
290.12 Dementia with cerebral degenerations Mental Disorders 1.06 0.842 – 1.34 0.605 88 846 all phecode
290.13 Senile dementia Mental Disorders 0.992 0.881 – 1.12 0.89 340 3078 all phecode
290.16 Vascular dementia Mental Disorders 0.835 0.66 – 1.06 0.131 81 777 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.03 0.955 – 1.12 0.411 750 7358 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.932 0.867 – 1 0.0538 886 8618 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.02 0.98 – 1.07 0.3 2550 24810 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.956 0.811 – 1.13 0.589 175 1750 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.958 0.869 – 1.06 0.383 484 4807 all phecode
291.8 Alteration of consciousness Mental Disorders 1.04 0.993 – 1.09 0.0927 2036 19974 all phecode
292 Neurological disorders Mental Disorders 1.03 0.999 – 1.06 0.0613 5733 38553 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.993 0.947 – 1.04 0.777 2013 19867 all phecode
292.11 Aphasia Mental Disorders 1 0.92 – 1.09 0.986 664 6581 all phecode
292.12 Symbolic dysfunction Mental Disorders 1.01 0.871 – 1.18 0.864 200 1988 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.954 0.855 – 1.06 0.402 389 3731 all phecode
292.3 Memory loss Mental Disorders 0.961 0.915 – 1.01 0.113 1922 18158 all phecode
292.4 Altered mental status Mental Disorders 1.08 1.04 – 1.13 0.000335 2454 22725 all phecode
292.5 Transient alteration of awareness Mental Disorders 1.03 0.929 – 1.14 0.586 430 4285 all phecode
292.6 Hallucinations Mental Disorders 1.1 0.944 – 1.27 0.23 217 2147 all phecode
293 Symptoms involving head and neck Mental Disorders 0.899 0.809 – 1 0.0493 414 4127 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.02 0.984 – 1.05 0.333 4417 38609 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.07 0.998 – 1.15 0.0577 885 8229 all phecode
295.1 Schizophrenia Mental Disorders 0.933 0.778 – 1.12 0.459 138 1339 all phecode
295.2 Paranoid disorders Mental Disorders 1.1 0.897 – 1.34 0.369 118 1079 all phecode
295.3 Psychosis Mental Disorders 1.09 1.01 – 1.19 0.0317 716 6694 all phecode
296 Mood disorders Mental Disorders 1.08 1.06 – 1.1 1.94e-11 15356 20858 all phecode
296.1 Bipolar Mental Disorders 1.15 1.08 – 1.22 9.79e-06 1301 11264 all phecode
296.2 Depression Mental Disorders 1.08 1.05 – 1.1 4.82e-11 14833 20856 all phecode
296.22 Major depressive disorder Mental Disorders 1.08 1.06 – 1.11 4.38e-11 13850 20853 all phecode
297 Suicidal ideation or attempt Mental Disorders 1.09 1.02 – 1.17 0.0169 985 9050 all phecode
297.1 Suicidal ideation Mental Disorders 1.09 1.01 – 1.17 0.0344 788 7310 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.02 0.899 – 1.16 0.756 285 2654 all phecode
300 Anxiety disorders Mental Disorders 1.05 1.03 – 1.08 7.71e-06 15419 20850 all phecode
300.1 Anxiety disorder Mental Disorders 1.06 1.04 – 1.08 9e-07 14517 20855 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1.05 1.02 – 1.08 0.00362 5546 20512 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.05 0.988 – 1.12 0.114 1360 11377 all phecode
300.13 Phobia Mental Disorders 1.07 0.996 – 1.14 0.0659 1051 9542 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.906 0.805 – 1.02 0.0997 328 3018 all phecode
300.4 Dysthymic disorder Mental Disorders 1.07 1.02 – 1.12 0.00589 2420 16552 all phecode
300.8 Acute reaction to stress Mental Disorders 1.02 0.926 – 1.13 0.662 504 4825 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.12 1.04 – 1.21 0.00222 843 7909 all phecode
301 Personality disorders Mental Disorders 1.1 0.997 – 1.22 0.0567 477 4539 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.09 0.949 – 1.25 0.227 254 2393 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.972 0.935 – 1.01 0.149 3700 13808 all phecode
302.1 Decreased libido Mental Disorders 0.921 0.833 – 1.02 0.108 447 4331 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.936 0.908 – 0.964 1.03e-05 6808 20043 all phecode
303.1 Dissociative disorder Mental Disorders 1.14 0.962 – 1.35 0.13 161 1573 all phecode
303.3 Psychogenic disorder Mental Disorders 0.925 0.897 – 0.953 4.16e-07 6487 19888 all phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.943 0.854 – 1.04 0.249 471 4623 all phecode
303.4 Somatoform disorder Mental Disorders 0.994 0.933 – 1.06 0.85 1177 11180 all phecode
304 Adjustment reaction Mental Disorders 1.03 0.993 – 1.07 0.119 3888 20475 all phecode
305.2 Eating disorder Mental Disorders 1.29 1.2 – 1.38 1.71e-11 901 8329 all phecode
306 Other mental disorder Mental Disorders 1.03 0.981 – 1.09 0.215 1815 14133 all phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.05 0.958 – 1.16 0.282 587 3527 all phecode
306.9 Tension headache Mental Disorders 1.04 0.964 – 1.13 0.289 753 7277 all phecode
312 Conduct disorders Mental Disorders 1.07 0.937 – 1.22 0.318 254 2501 all phecode
312.3 Impulse control disorder Mental Disorders 0.95 0.748 – 1.21 0.675 74 736 all phecode
313 Pervasive developmental disorders Mental Disorders 1.05 0.994 – 1.11 0.084 1571 14633 all phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1.04 0.983 – 1.1 0.166 1392 13190 all phecode
313.2 Tics and stuttering Mental Disorders 1.16 0.912 – 1.47 0.227 77 770 all phecode
313.3 Autism Mental Disorders 0.903 0.694 – 1.17 0.448 64 621 all phecode
315 Develomental delays and disorders Mental Disorders 1.06 0.975 – 1.15 0.17 684 6788 all phecode
315.1 Learning disorder Mental Disorders 1.12 0.904 – 1.38 0.306 87 860 all phecode
315.2 Speech and language disorder Mental Disorders 0.936 0.818 – 1.07 0.342 254 2539 all phecode
316 Substance addiction and disorders Mental Disorders 1.13 1.09 – 1.17 8.5e-12 3682 32680 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.976 0.896 – 1.06 0.579 634 6331 all phecode
317 Alcohol-related disorders Mental Disorders 1.06 1.02 – 1.11 0.00432 2525 22920 all phecode
317.1 Alcoholism Mental Disorders 1.06 1.01 – 1.11 0.0212 1986 19339 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.02 0.922 – 1.14 0.659 408 4080 all phecode
318 Tobacco use disorder Mental Disorders 1.19 1.16 – 1.22 4.2e-42 8622 34842 all phecode
320 Meningitis Neurological 1.01 0.908 – 1.13 0.802 382 3820 all phecode
323 Encephalitis Neurological 1.03 0.883 – 1.21 0.677 181 1809 all phecode
323.8 Encephalitis, non-infectious Neurological 1.05 0.881 – 1.24 0.611 153 1527 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.17 1.03 – 1.33 0.016 288 2880 all phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 1 0.751 – 1.33 0.999 53 530 all phecode
327 Sleep disorders Neurological 1.18 1.15 – 1.2 1.65e-52 14941 31602 all phecode
327.1 Hypersomnia Neurological 1.09 1.04 – 1.15 0.000268 2061 19110 all phecode
327.3 Sleep apnea Neurological 1.26 1.23 – 1.29 7.35e-80 10909 31304 all phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1.05 0.954 – 1.16 0.32 492 4784 all phecode
327.32 Obstructive sleep apnea Neurological 1.26 1.23 – 1.3 4.38e-71 8744 30530 all phecode
327.4 Insomnia Neurological 1.07 1.03 – 1.1 4.32e-05 5524 30960 all phecode
327.41 Organic or persistent insomnia Neurological 1.02 0.957 – 1.08 0.576 1265 12120 all phecode
327.5 Parasomnia Neurological 1.17 1.07 – 1.27 0.000624 604 5913 all phecode
327.6 Circadian rhythm sleep disorder Neurological 1.09 0.953 – 1.24 0.213 274 2666 all phecode
327.7 Sleep related movement disorders Neurological 1.15 1.1 – 1.21 7.04e-08 1786 17323 all phecode
327.71 Restless legs syndrome Neurological 1.17 1.1 – 1.23 6.62e-08 1570 15360 all phecode
327.72 Sleep related leg cramps Neurological 0.999 0.787 – 1.27 0.993 83 822 all phecode
331 Other cerebral degenerations Neurological 0.923 0.852 – 1 0.0504 717 7024 all phecode
331.1 Hydrocephalus Neurological 0.939 0.828 – 1.06 0.322 284 2836 all phecode
331.9 Cerebral degeneration, unspecified Neurological 0.949 0.855 – 1.05 0.324 419 4026 all phecode
332 Parkinson's disease Neurological 0.894 0.803 – 0.996 0.0415 415 4128 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.05 1 – 1.09 0.0304 2868 26583 all phecode
333.1 Essential tremor Neurological 0.981 0.906 – 1.06 0.645 725 7163 all phecode
333.2 Myoclonus Neurological 1.15 0.975 – 1.36 0.0971 159 1590 all phecode
333.4 Torsion dystonia Neurological 0.865 0.77 – 0.971 0.0143 352 3504 all phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 0.858 0.686 – 1.07 0.18 89 890 all phecode
334 Degenerative disease of the spinal cord Neurological 1.09 1.01 – 1.16 0.017 1058 10562 all phecode
334.1 Spinocerebellar disease Neurological 1.11 0.877 – 1.42 0.377 79 790 all phecode
334.2 Anterior horn cell disease Neurological 0.963 0.783 – 1.18 0.721 110 1080 all phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 0.892 0.69 – 1.15 0.384 71 693 all phecode
335 Multiple sclerosis Neurological 1.12 1 – 1.25 0.0403 396 3951 all phecode
337 Disorders of the autonomic nervous system Neurological 1.05 0.976 – 1.14 0.183 808 7413 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.13 1.01 – 1.27 0.0313 370 3164 all phecode
338 Pain Neurological 1.07 1.05 – 1.09 2.58e-12 20346 26417 all phecode
338.1 Acute pain Neurological 1.06 1.04 – 1.08 4.69e-08 15582 26313 all phecode
338.2 Chronic pain Neurological 1.12 1.09 – 1.14 1.56e-19 10994 26368 all phecode
339 Other headache syndromes Neurological 1.04 1.01 – 1.07 0.00232 9242 34658 all phecode
340 Migraine Neurological 1.04 1.01 – 1.07 0.00305 6708 30587 all phecode
340.1 Migrain with aura Neurological 1.04 1 – 1.08 0.0285 3624 23684 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.07 0.891 – 1.29 0.47 133 1330 all phecode
342 Hemiplegia Neurological 1.04 0.945 – 1.15 0.402 464 4607 all phecode
343 Infantile cerebral palsy Neurological 0.968 0.772 – 1.21 0.776 85 847 all phecode
344 Other paralytic syndromes Neurological 1.05 0.964 – 1.14 0.278 682 6808 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.03 0.985 – 1.07 0.209 2553 25307 all phecode
345.1 Epilepsy Neurological 1 0.927 – 1.08 0.946 747 7465 all phecode
345.11 Generalized convulsive epilepsy Neurological 0.977 0.851 – 1.12 0.741 233 2330 all phecode
345.12 Partial epilepsy Neurological 0.999 0.91 – 1.1 0.983 534 5335 all phecode
345.3 Convulsions Neurological 1.03 0.985 – 1.08 0.194 2396 23796 all phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.979 0.837 – 1.15 0.795 183 1824 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1 0.946 – 1.06 0.971 1472 14587 all phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.93 0.768 – 1.13 0.457 120 1181 all phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 1 0.812 – 1.23 1 110 1100 all phecode
347 Cataplexy and narcolepsy Neurological 1.17 0.937 – 1.46 0.167 101 1010 all phecode
348 Other conditions of brain Neurological 1.07 1.02 – 1.13 0.00753 1793 17894 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.04 0.968 – 1.12 0.285 905 9034 all phecode
348.4 Cerebral cysts Neurological 1.01 0.879 – 1.17 0.845 229 2290 all phecode
348.7 Coma Neurological 1.02 0.882 – 1.17 0.83 229 2275 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.13 1.05 – 1.22 0.00125 853 8479 all phecode
348.9 Other conditions of brain, NOS Neurological 0.983 0.94 – 1.03 0.455 2341 23287 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.05 0.974 – 1.12 0.217 941 9385 all phecode
350 Abnormal movement Neurological 1.03 1 – 1.06 0.0276 6706 38762 all phecode
350.1 Abnormal involuntary movements Neurological 1.03 0.987 – 1.07 0.199 3273 30524 all phecode
350.2 Abnormality of gait Neurological 1.04 1 – 1.08 0.0403 3920 30520 all phecode
350.3 Lack of coordination Neurological 0.964 0.903 – 1.03 0.27 1062 10554 all phecode
350.5 Abnormal reflex Neurological 0.983 0.845 – 1.14 0.82 200 1988 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.969 0.884 – 1.06 0.502 558 5576 all phecode
351 Other peripheral nerve disorders Neurological 1.1 1.07 – 1.13 1.85e-12 7401 34460 all phecode
352 Disorders of other cranial nerves Neurological 1.02 0.968 – 1.08 0.45 1714 17106 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.981 0.893 – 1.08 0.694 535 5344 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.04 0.962 – 1.12 0.326 783 7826 all phecode
353 Nerve root and plexus disorders Neurological 1.08 1.05 – 1.12 5.41e-06 4256 33369 all phecode
353.1 Nerve plexus lesions Neurological 1.1 0.987 – 1.23 0.0834 390 3900 all phecode
353.2 Nerve root lesions Neurological 1.03 0.856 – 1.25 0.734 130 1287 all phecode
355 Complex regional/central pain syndrome Neurological 1.07 0.97 – 1.17 0.188 531 5295 all phecode
355.1 Chronic pain syndrome Neurological 1.15 1.07 – 1.24 0.000161 843 8386 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.08 1.03 – 1.13 0.00114 2335 20731 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.11 1.07 – 1.16 1.17e-08 3472 29956 all phecode
358 Myoneural disorders Neurological 1.11 1.04 – 1.18 0.00201 1147 11391 all phecode
358.1 Myasthenia gravis Neurological 0.882 0.719 – 1.08 0.228 109 1082 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.967 0.907 – 1.03 0.316 1134 11274 all phecode
359.1 Muscular dystrophies Neurological 0.937 0.7 – 1.25 0.662 64 632 all phecode
359.2 Myopathy Neurological 0.977 0.914 – 1.04 0.489 1092 10843 all phecode
360 Disorders of the globe Sense Organs 0.881 0.729 – 1.06 0.19 131 1276 all phecode
360.2 Progressive myopia Sense Organs 0.783 0.6 – 1.02 0.0701 65 640 all phecode
361 Retinal detachments and defects Sense Organs 0.928 0.856 – 1.01 0.0701 733 7131 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.83 0.73 – 0.943 0.00426 302 2962 all phecode
362 Other retinal disorders Sense Organs 0.982 0.945 – 1.02 0.358 3569 22997 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.963 0.917 – 1.01 0.124 2172 15483 all phecode
362.21 Macular degeneration, dry Sense Organs 0.868 0.776 – 0.97 0.0122 419 3438 all phecode
362.22 Macular degeneration, wet Sense Organs 0.978 0.816 – 1.17 0.814 148 1184 all phecode
362.23 Cystoid macular degeneration of retina Sense Organs 0.916 0.821 – 1.02 0.114 408 3839 all phecode
362.26 Macular puckering of retina Sense Organs 0.951 0.886 – 1.02 0.157 976 8610 all phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.893 0.807 – 0.988 0.0286 488 4558 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.971 0.922 – 1.02 0.27 1883 13955 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.05 0.977 – 1.13 0.185 976 8527 all phecode
362.31 Separation of retinal layers Sense Organs 0.976 0.877 – 1.09 0.656 413 4056 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.01 0.93 – 1.1 0.769 662 5933 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.872 0.781 – 0.974 0.0157 392 3787 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.916 0.791 – 1.06 0.239 215 2103 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.15 1 – 1.32 0.0458 241 2368 all phecode
362.9 Retinal edema Sense Organs 1.09 0.969 – 1.23 0.151 324 2936 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.897 0.813 – 0.989 0.0291 492 4746 all phecode
363.3 Chorioretinal scars Sense Organs 0.849 0.755 – 0.956 0.00658 332 3184 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.971 0.909 – 1.04 0.377 1132 10772 all phecode
364.1 Corneal opacity Sense Organs 0.937 0.841 – 1.04 0.237 394 3846 all phecode
364.2 Corneal edema Sense Organs 1.07 0.883 – 1.29 0.505 123 1208 all phecode
364.4 Corneal degenerations Sense Organs 0.968 0.868 – 1.08 0.563 402 3962 all phecode
364.41 Keratoconus Sense Organs 0.784 0.612 – 1.01 0.056 75 739 all phecode
364.5 Corneal dystrophy Sense Organs 0.986 0.892 – 1.09 0.776 502 4682 all phecode
364.51 Fuchs' dystrophy Sense Organs 0.912 0.796 – 1.04 0.183 266 2521 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.896 0.718 – 1.12 0.331 91 885 all phecode
365 Glaucoma Sense Organs 0.975 0.934 – 1.02 0.245 2672 21326 all phecode
365.1 Open-angle glaucoma Sense Organs 0.927 0.853 – 1.01 0.0715 705 6491 all phecode
365.11 Primary open angle glaucoma Sense Organs 0.899 0.806 – 1 0.0568 403 3681 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.974 0.844 – 1.12 0.717 251 2370 all phecode
366 Cataract Sense Organs 0.977 0.95 – 1 0.0905 8611 28043 all phecode
366.1 Nonsenile Cataract Sense Organs 0.921 0.792 – 1.07 0.288 207 1979 all phecode
366.2 Senile cataract Sense Organs 0.96 0.929 – 0.992 0.0134 5480 24980 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.965 0.941 – 0.989 0.00456 8967 37779 all phecode
367.1 Myopia Sense Organs 0.939 0.909 – 0.969 9.78e-05 5014 34677 all phecode
367.2 Astigmatism Sense Organs 0.93 0.898 – 0.962 3.36e-05 4161 32463 all phecode
367.8 Hypermetropia Sense Organs 0.938 0.894 – 0.985 0.0101 2039 18599 all phecode
367.9 Blindness and low vision Sense Organs 1.04 0.98 – 1.11 0.189 1277 12356 all phecode
368 Visual disturbances Sense Organs 1.02 0.986 – 1.05 0.313 5715 39599 all phecode
368.1 Amblyopia Sense Organs 1.03 0.949 – 1.13 0.441 651 6479 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.997 0.934 – 1.06 0.928 1087 10786 all phecode
368.3 Anisometropia Sense Organs 0.812 0.701 – 0.941 0.00573 219 2168 all phecode
368.4 Visual field defects Sense Organs 1.02 0.957 – 1.09 0.533 1132 11173 all phecode
368.9 Subjective visual disturbances Sense Organs 1.03 0.96 – 1.1 0.445 1070 10620 all phecode
368.91 Psychophysical visual disturbances Sense Organs 1.27 1.04 – 1.54 0.0184 120 1171 all phecode
369 Infection of the eye Sense Organs 0.944 0.908 – 0.982 0.00397 3185 28240 all phecode
369.2 Eye infection, viral Sense Organs 0.941 0.853 – 1.04 0.232 502 4954 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.948 0.909 – 0.989 0.0126 2716 24970 all phecode
370 Keratitis Sense Organs 0.917 0.865 – 0.973 0.0039 1365 13169 all phecode
370.1 Corneal ulcer Sense Organs 0.899 0.779 – 1.04 0.15 223 2194 all phecode
370.2 Superficial keratitis Sense Organs 0.909 0.829 – 0.997 0.0431 546 5393 all phecode
370.3 Keratoconjunctivitis Sense Organs 0.977 0.897 – 1.06 0.595 649 6263 all phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.958 0.811 – 1.13 0.611 179 1677 all phecode
371 Inflammation of the eye Sense Organs 0.939 0.908 – 0.971 0.000244 4414 32310 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.984 0.897 – 1.08 0.731 541 5278 all phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.942 0.877 – 1.01 0.107 906 8939 all phecode
371.21 Allergic conjunctivitis Sense Organs 0.929 0.858 – 1.01 0.0672 756 7515 all phecode
371.3 Inflammation of eyelids Sense Organs 0.927 0.893 – 0.963 0.000105 3398 26983 all phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 0.846 0.699 – 1.02 0.0858 133 1291 all phecode
372 Disorders of conjunctiva Sense Organs 0.957 0.897 – 1.02 0.186 1118 10728 all phecode
374 Other disorders of eyelids Sense Organs 0.933 0.896 – 0.972 0.00087 2940 24188 all phecode
374.1 Ectropion or entropion Sense Organs 0.903 0.814 – 1 0.0544 431 4084 all phecode
374.2 Lagophthalmos Sense Organs 0.987 0.857 – 1.14 0.855 235 2335 all phecode
374.3 Ptosis of eyelid Sense Organs 0.947 0.887 – 1.01 0.104 1102 10734 all phecode
374.6 Dermatochalasis Sense Organs 0.948 0.886 – 1.01 0.124 1040 9720 all phecode
375 Disorders of lacrimal system Sense Organs 0.962 0.927 – 0.998 0.041 3694 26045 all phecode
375.1 Dry eyes Sense Organs 0.962 0.928 – 0.997 0.0346 4040 26751 all phecode
375.2 Epiphora Sense Organs 0.966 0.87 – 1.07 0.525 442 4354 all phecode
376 Disorders of the orbit Sense Organs 0.988 0.881 – 1.11 0.841 352 3508 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.04 0.969 – 1.12 0.278 913 9021 all phecode
377.1 Optic atrophy Sense Organs 0.969 0.85 – 1.1 0.633 283 2793 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.05 0.963 – 1.15 0.255 585 5775 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.949 0.893 – 1.01 0.0887 1275 12460 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.957 0.887 – 1.03 0.25 828 8130 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.957 0.813 – 1.13 0.6 170 1686 all phecode
378.5 Paralytic strabismus Sense Organs 0.894 0.797 – 1 0.0567 349 3437 all phecode
379 Other disorders of eye Sense Organs 0.945 0.915 – 0.976 0.000662 5046 29999 all phecode
379.1 Scleritis and episcleritis Sense Organs 0.867 0.734 – 1.02 0.0947 176 1743 all phecode
379.2 Disorders of vitreous body Sense Organs 0.932 0.897 – 0.968 0.000285 3634 23186 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.823 0.682 – 0.993 0.042 135 1258 all phecode
379.4 Anomalies of pupillary function Sense Organs 0.972 0.857 – 1.1 0.665 287 2833 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.05 0.927 – 1.18 0.461 304 2948 all phecode
379.51 Pigmentary iris degeneration Sense Organs 0.814 0.634 – 1.04 0.104 77 731 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.987 0.925 – 1.05 0.693 1129 11130 all phecode
380 Disorders of external ear Sense Organs 0.922 0.88 – 0.965 0.000564 2242 20393 all phecode
380.1 Otitis externa Sense Organs 0.986 0.932 – 1.04 0.626 1469 14580 all phecode
380.4 Impacted cerumen Sense Organs 0.917 0.879 – 0.957 6.91e-05 2648 23557 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.999 0.966 – 1.03 0.962 4255 36417 all phecode
381.1 Otitis media Sense Organs 1.04 0.997 – 1.08 0.0737 3079 29813 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.04 0.996 – 1.08 0.0781 2610 25602 all phecode
381.2 Eustachian tube disorders Sense Organs 0.923 0.877 – 0.972 0.00218 1816 17827 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.11 0.937 – 1.32 0.223 153 1530 all phecode
381.9 Otorrhea Sense Organs 1.12 1 – 1.25 0.0437 372 3713 all phecode
382 Otalgia Sense Organs 1.03 0.979 – 1.08 0.265 1884 18673 all phecode
383 Otosclerosis Sense Organs 0.984 0.816 – 1.19 0.865 124 1240 all phecode
384 Other disorders of tympanic membrane Sense Organs 0.969 0.882 – 1.07 0.517 516 5156 all phecode
384.1 Myringitis Sense Organs 0.79 0.582 – 1.07 0.13 51 502 all phecode
384.4 Perforation of tympanic membrane Sense Organs 0.981 0.882 – 1.09 0.719 403 4029 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.01 0.917 – 1.12 0.775 432 4320 all phecode
385.3 Cholesteatoma Sense Organs 1.02 0.901 – 1.16 0.726 277 2770 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.02 0.845 – 1.24 0.826 118 1180 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.01 0.96 – 1.06 0.7 1882 18186 all phecode
386.1 Meniere's disease Sense Organs 1.05 0.926 – 1.19 0.457 319 3156 all phecode
386.2 Peripheral or central vertigo Sense Organs 1.01 0.951 – 1.06 0.849 1586 15423 all phecode
386.21 Central origin vertigo Sense Organs 1.02 0.954 – 1.08 0.612 1208 11844 all phecode
386.3 Labyrinthitis Sense Organs 1.01 0.954 – 1.07 0.737 1482 14530 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.04 1.01 – 1.07 0.00635 6933 38286 all phecode
388 Other disorders of ear Sense Organs 0.976 0.91 – 1.05 0.486 960 9501 all phecode
389 Hearing loss Sense Organs 0.982 0.958 – 1.01 0.178 8182 38069 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.936 0.904 – 0.969 0.00018 4107 29258 all phecode
389.2 Conductive hearing loss Sense Organs 0.972 0.905 – 1.04 0.435 905 9042 all phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.866 0.74 – 1.01 0.0748 192 1808 all phecode
389.4 Tinnitus Sense Organs 0.919 0.879 – 0.962 0.000272 2291 22130 all phecode
389.5 Disorders of acoustic nerve Sense Organs 1.1 0.911 – 1.33 0.318 124 1229 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.04 0.984 – 1.1 0.156 1458 13732 all phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 1.02 0.904 – 1.14 0.785 350 3415 all phecode
394.2 Mitral valve disease Circulatory System 0.997 0.901 – 1.1 0.948 462 4560 all phecode
394.3 Aortic valve disease Circulatory System 1.07 0.908 – 1.27 0.406 176 1691 all phecode
394.4 Acute rheumatic heart disease Circulatory System 0.97 0.733 – 1.28 0.832 55 546 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.07 0.982 – 1.17 0.119 587 5739 all phecode
395 Heart valve disorders Circulatory System 1.01 0.974 – 1.05 0.603 3976 28748 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.952 0.908 – 0.997 0.0382 2175 20441 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.08 1.03 – 1.14 0.00174 2060 17194 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.05 0.948 – 1.15 0.377 493 4864 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1 0.815 – 1.24 0.967 108 1080 all phecode
395.6 Heart valve replaced Circulatory System 1.06 0.998 – 1.13 0.0576 1177 10833 all phecode
396 Abnormal heart sounds Circulatory System 1.02 0.984 – 1.05 0.341 4718 34395 all phecode
401 Hypertension Circulatory System 1.3 1.27 – 1.33 2.4e-120 23317 23367 all phecode
401.1 Essential hypertension Circulatory System 1.3 1.27 – 1.33 2.21e-121 23158 23364 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.43 1.37 – 1.49 5.92e-61 3503 14616 all phecode
401.21 Hypertensive heart disease Circulatory System 1.32 1.22 – 1.42 5.98e-13 893 6607 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.44 1.37 – 1.51 2.22e-49 2584 13072 all phecode
401.3 Other hypertensive complications Circulatory System 1.3 1.24 – 1.36 4.33e-30 2679 15833 all phecode
411 Ischemic Heart Disease Circulatory System 1.16 1.13 – 1.19 3.67e-28 8807 30299 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.2 1.11 – 1.29 8.17e-07 937 8574 all phecode
411.2 Myocardial infarction Circulatory System 1.21 1.17 – 1.26 3.05e-23 3594 21716 all phecode
411.3 Angina pectoris Circulatory System 1.18 1.12 – 1.23 1.19e-12 2485 18304 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.16 1.13 – 1.2 6.59e-25 7555 27492 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.15 0.96 – 1.38 0.13 156 1529 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.17 1.14 – 1.21 1.89e-24 6331 25741 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.18 1.07 – 1.31 0.0014 442 4211 all phecode
414 Other forms of chronic heart disease Circulatory System 1.11 1.06 – 1.15 8.34e-07 3101 22616 all phecode
414.2 ASCVD Circulatory System 1.09 1 – 1.18 0.0377 718 6816 all phecode
415 Pulmonary heart disease Circulatory System 1.15 1.11 – 1.19 2.77e-13 3366 30208 all phecode
415.1 Acute pulmonary heart disease Circulatory System 1.13 1.07 – 1.18 1.96e-06 1912 19014 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.13 1.07 – 1.19 1.78e-06 1906 18953 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.18 1.12 – 1.25 1.26e-10 1808 17605 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.16 1.07 – 1.25 0.000522 706 7032 all phecode
416 Cardiomegaly Circulatory System 1.1 1.03 – 1.17 0.00272 1254 12372 all phecode
418 Nonspecific chest pain Circulatory System 1.05 1.03 – 1.07 6.77e-06 12650 33952 all phecode
418.1 Precordial pain Circulatory System 1.04 0.985 – 1.1 0.15 1471 13782 all phecode
420 Carditis Circulatory System 1.07 1.01 – 1.13 0.0221 1588 15680 all phecode
420.1 Myocarditis Circulatory System 1.03 0.828 – 1.28 0.792 97 958 all phecode
420.2 Pericarditis Circulatory System 1.07 0.988 – 1.15 0.0983 842 8402 all phecode
420.21 Acute pericarditis Circulatory System 1.24 1.06 – 1.46 0.00884 177 1764 all phecode
420.22 Chronic pericarditis Circulatory System 1.25 1.03 – 1.53 0.0267 117 1153 all phecode
420.3 Endocarditis Circulatory System 1.11 1.02 – 1.2 0.0108 764 7535 all phecode
425 Cardiomyopathy Circulatory System 1.12 1.07 – 1.18 1.8e-06 2078 19881 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.13 1.08 – 1.19 4.69e-07 1989 19025 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.05 0.908 – 1.22 0.491 208 2050 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.1 0.941 – 1.28 0.241 201 1992 all phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.02 0.901 – 1.15 0.765 317 3170 all phecode
425.8 Other cardiomyopathy Circulatory System 1.12 0.891 – 1.4 0.336 95 931 all phecode
426 Cardiac conduction disorders Circulatory System 1.09 1.06 – 1.11 1.62e-11 12327 25440 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.13 1.07 – 1.19 1.11e-05 1903 11501 all phecode
426.21 First degree AV block Circulatory System 1.11 1.05 – 1.18 0.000798 1313 8899 all phecode
426.22 Mobitz II AV block Circulatory System 0.954 0.72 – 1.26 0.741 64 553 all phecode
426.23 Second degree AV block Circulatory System 0.993 0.854 – 1.16 0.932 216 1925 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.05 0.945 – 1.16 0.381 461 3823 all phecode
426.25 Other heart block Circulatory System 1.03 0.883 – 1.19 0.732 203 1803 all phecode
426.3 Bundle branch block Circulatory System 1.08 1.03 – 1.13 0.00249 2306 13999 all phecode
426.31 Right bundle branch block Circulatory System 1.06 1 – 1.12 0.0505 1423 10758 all phecode
426.32 Left bundle branch block Circulatory System 1.12 1.04 – 1.2 0.00172 969 8110 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.04 0.825 – 1.31 0.74 82 820 all phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.09 1.06 – 1.12 1e-10 10577 25186 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.13 1.04 – 1.23 0.00557 679 6650 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.1 1.04 – 1.16 0.000523 1754 11536 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.12 1.05 – 1.2 0.000783 1171 8184 all phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.1 1.02 – 1.19 0.013 846 7320 all phecode
427 Cardiac dysrhythmias Circulatory System 1.05 1.03 – 1.08 5.89e-07 17397 25735 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.05 1.01 – 1.1 0.0189 2474 18178 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.06 1 – 1.12 0.0497 1595 14293 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.08 1.01 – 1.15 0.0176 1181 9915 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.09 1.06 – 1.13 2.84e-07 5313 18688 all phecode
427.21 Atrial fibrillation Circulatory System 1.09 1.05 – 1.13 1.19e-06 5188 18409 all phecode
427.22 Atrial flutter Circulatory System 1.08 1.03 – 1.14 0.00355 1693 11042 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.06 1.03 – 1.09 1.55e-05 8688 25552 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.06 0.961 – 1.16 0.257 536 5233 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.907 0.784 – 1.05 0.185 216 2118 all phecode
427.42 Cardiac arrest Circulatory System 1.11 0.996 – 1.23 0.0586 410 4034 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.04 1.01 – 1.07 0.00681 6905 25457 all phecode
427.6 Premature beats Circulatory System 1.03 0.983 – 1.08 0.217 2359 16248 all phecode
427.61 Supraventricular premature beats Circulatory System 1.08 0.991 – 1.17 0.0798 670 6287 all phecode
427.7 Tachycardia NOS Circulatory System 1.1 1.06 – 1.13 8.84e-09 5124 25531 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.09 1.01 – 1.17 0.0189 912 7501 all phecode
427.9 Palpitations Circulatory System 0.993 0.959 – 1.03 0.668 4430 24505 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.22 1.18 – 1.26 4.26e-28 4300 23663 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.22 1.18 – 1.27 1.06e-25 3756 22446 all phecode
428.2 Heart failure NOS Circulatory System 1.25 1.2 – 1.3 3.81e-30 3701 21722 all phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.2 1.14 – 1.26 1.15e-11 1765 14476 all phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.29 1.22 – 1.36 2.81e-19 1648 13395 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.07 1.04 – 1.09 7.7e-09 12635 32504 all phecode
429.1 Heart transplant/surgery Circulatory System 1.09 1.02 – 1.16 0.00939 1219 11696 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.1 1.07 – 1.13 3.7e-10 6322 29232 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.06 1.04 – 1.09 1.8e-06 9650 32421 all phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.1 1.02 – 1.19 0.0179 723 7072 all phecode
430 Intracranial hemorrhage Circulatory System 0.936 0.867 – 1.01 0.0896 789 7842 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 1 0.877 – 1.15 0.966 261 2610 all phecode
430.2 Intracerebral hemorrhage Circulatory System 0.972 0.868 – 1.09 0.621 368 3671 all phecode
430.3 Subdural hemorrhage Circulatory System 0.861 0.757 – 0.979 0.022 272 2680 all phecode
433 Cerebrovascular disease Circulatory System 1.09 1.06 – 1.13 1.18e-08 5463 32242 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.09 1.04 – 1.15 0.000461 1978 16212 all phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.26 1.1 – 1.45 0.000927 260 2517 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.11 0.869 – 1.42 0.4 80 789 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.13 1.08 – 1.18 6.06e-08 2437 21732 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.13 1.08 – 1.18 9.51e-08 2357 21103 all phecode
433.3 Cerebral ischemia Circulatory System 1.07 1.03 – 1.11 0.00173 2780 22868 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.09 1.04 – 1.14 0.000118 2409 20762 all phecode
433.5 Cerebral aneurysm Circulatory System 1.02 0.92 – 1.12 0.754 474 4724 all phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.14 1.03 – 1.26 0.0138 464 4518 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.14 1.05 – 1.24 0.00117 695 6822 all phecode
440 Atherosclerosis Circulatory System 1.15 1.1 – 1.2 1.06e-09 2477 19724 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.05 0.915 – 1.22 0.464 231 2291 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.13 1.07 – 1.2 1.14e-05 1516 13532 all phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.22 1.07 – 1.4 0.00239 274 2669 all phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.13 1.05 – 1.21 0.000501 1040 9647 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.2 1.12 – 1.3 1.51e-06 846 8124 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.07 0.977 – 1.18 0.14 515 5115 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.08 0.939 – 1.23 0.289 240 2387 all phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.1 0.924 – 1.31 0.288 154 1536 all phecode
442 Other aneurysm Circulatory System 1.1 1.05 – 1.14 1.37e-05 2779 21466 all phecode
442.1 Aortic aneurysm Circulatory System 1.1 1.05 – 1.15 0.000106 2054 16492 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.08 1.01 – 1.15 0.0174 1189 10558 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.15 0.985 – 1.34 0.0778 202 2002 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1 0.856 – 1.18 0.971 179 1765 all phecode
442.4 Arterial dissection Circulatory System 1.01 0.865 – 1.18 0.891 184 1840 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.13 1.01 – 1.25 0.0332 399 3978 all phecode
443 Peripheral vascular disease Circulatory System 1.08 1.03 – 1.12 0.00032 3086 24814 all phecode
443.1 Raynaud's syndrome Circulatory System 0.863 0.797 – 0.935 0.000286 742 7390 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.36 1.17 – 1.58 6.49e-05 220 2087 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.08 1.03 – 1.13 0.000507 2557 21985 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.14 1.09 – 1.19 1.39e-08 2341 18862 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.11 1.03 – 1.19 0.00807 848 8423 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.02 0.902 – 1.15 0.755 313 3099 all phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 1.04 0.875 – 1.23 0.667 155 1548 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.02 0.918 – 1.12 0.757 460 4559 all phecode
446.4 Wegener's granulomatosis Circulatory System 0.837 0.682 – 1.03 0.0905 109 1075 all phecode
446.5 Giant cell arteritis Circulatory System 0.835 0.653 – 1.07 0.148 79 749 all phecode
446.9 Arteritis NOS Circulatory System 1.04 0.917 – 1.18 0.529 289 2876 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.09 1.04 – 1.13 0.000134 2647 22765 all phecode
447.1 Stricture of artery Circulatory System 1.13 1.03 – 1.24 0.0123 523 5163 all phecode
447.7 Aortic ectasia Circulatory System 1.04 0.96 – 1.12 0.369 804 7938 all phecode
448 Disease of capillaries Circulatory System 0.862 0.81 – 0.918 3.13e-06 1237 12127 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.06 1.02 – 1.12 0.00992 2104 20985 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.03 0.952 – 1.12 0.449 738 7355 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.09 0.948 – 1.25 0.225 244 2437 all phecode
452 Other venous embolism and thrombosis Circulatory System 1.11 1.08 – 1.15 3.88e-11 4957 29867 all phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1.02 0.895 – 1.16 0.785 276 2747 all phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1.11 1.07 – 1.15 1.37e-07 3260 26940 all phecode
452.8 Postphlebitic syndrome Circulatory System 1.09 0.922 – 1.29 0.316 154 1529 all phecode
453 Chronic venous hypertension Circulatory System 1.18 1.02 – 1.37 0.0252 220 2168 all phecode
454 Varicose veins Circulatory System 1.06 1.02 – 1.11 0.00398 2827 24555 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1.08 1.03 – 1.13 0.000871 2469 21426 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.08 1.03 – 1.15 0.00381 1565 15056 all phecode
455 Hemorrhoids Circulatory System 0.965 0.936 – 0.994 0.0199 5799 29818 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.08 1.04 – 1.12 0.000161 3097 24898 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.11 1.05 – 1.16 4.51e-05 2095 15309 all phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.14 1.01 – 1.29 0.0292 324 3221 all phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.1 1.05 – 1.16 0.000145 1973 14689 all phecode
458 Hypotension Circulatory System 1.11 1.07 – 1.14 1.95e-10 5091 32185 all phecode
458.1 Orthostatic hypotension Circulatory System 1.07 1.01 – 1.14 0.0177 1344 12938 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.14 1.07 – 1.21 0.000111 1109 11012 all phecode
458.9 Hypotension NOS Circulatory System 1.11 1.07 – 1.15 8.82e-10 4618 31186 all phecode
459 Other disorders of circulatory system Circulatory System 1.09 1.06 – 1.12 7.25e-11 7825 34792 all phecode
459.1 Hemorrhage NOS Circulatory System 1.03 0.955 – 1.11 0.445 834 8215 all phecode
459.7 Blood vessel replaced Circulatory System 1.18 1.11 – 1.25 8.06e-08 1305 13023 all phecode
459.9 Circulatory disease NEC Circulatory System 1.09 1.06 – 1.12 2.12e-09 6706 33592 all phecode
464 Acute sinusitis Respiratory 0.97 0.939 – 1 0.0676 4792 32137 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.969 0.946 – 0.992 0.00925 9601 35915 all phecode
465.2 Acute pharyngitis Respiratory 0.951 0.922 – 0.981 0.00153 5310 32365 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.03 0.929 – 1.14 0.583 443 4428 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.915 0.87 – 0.963 0.000671 1797 17640 all phecode
471 Nasal polyps Respiratory 0.93 0.852 – 1.02 0.108 592 5881 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.975 0.926 – 1.03 0.326 1797 16986 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1.01 0.968 – 1.05 0.731 2983 25244 all phecode
473.1 Chronic laryngitis Respiratory 1.1 0.852 – 1.41 0.476 68 674 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.987 0.906 – 1.07 0.757 628 6254 all phecode
473.4 Voice disturbance Respiratory 1.01 0.966 – 1.06 0.663 2336 21975 all phecode
474 Acute and chronic tonsillitis Respiratory 1.03 0.956 – 1.11 0.451 880 7892 all phecode
474.1 Acute tonsillitis Respiratory 0.885 0.785 – 0.996 0.0436 335 3181 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.07 0.982 – 1.16 0.127 700 6445 all phecode
475 Chronic sinusitis Respiratory 0.964 0.932 – 0.997 0.0326 4378 27891 all phecode
475.9 Postnasal drip Respiratory 0.898 0.836 – 0.966 0.00373 922 9017 all phecode
476 Allergic rhinitis Respiratory 0.981 0.959 – 1 0.0891 12687 28117 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.07 1.01 – 1.15 0.0264 1150 11318 all phecode
478 Throat pain Respiratory 0.957 0.862 – 1.06 0.414 426 4195 all phecode
479 Other upper respiratory disease Respiratory 0.997 0.968 – 1.03 0.857 5627 28048 all phecode
480 Pneumonia Respiratory 1.09 1.06 – 1.12 6.28e-09 5947 37034 all phecode
480.1 Bacterial pneumonia Respiratory 1.1 1.03 – 1.17 0.00412 1155 11495 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.12 1.02 – 1.23 0.0169 568 5644 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.05 0.881 – 1.26 0.57 153 1523 all phecode
480.13 MRSA pneumonia Respiratory 1.12 0.919 – 1.36 0.265 117 1165 all phecode
480.2 Viral pneumonia Respiratory 1.15 0.987 – 1.33 0.0731 202 1992 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.14 0.958 – 1.35 0.143 159 1590 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.08 0.895 – 1.3 0.433 135 1312 all phecode
481 Influenza Respiratory 1.02 0.959 – 1.08 0.551 1355 13284 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.03 0.994 – 1.07 0.101 3412 29871 all phecode
495 Asthma Respiratory 1.13 1.1 – 1.16 9e-22 8671 33569 all phecode
495.1 Chronic obstructive asthma Respiratory 1.27 1.14 – 1.41 2.05e-05 397 3925 all phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 1.21 0.942 – 1.55 0.137 81 802 all phecode
495.2 Asthma with exacerbation Respiratory 1.08 1.03 – 1.15 0.00316 1629 16033 all phecode
496 Chronic airway obstruction Respiratory 1.19 1.16 – 1.23 4.11e-28 5343 28343 all phecode
496.1 Emphysema Respiratory 1.15 1.1 – 1.21 4.98e-09 2134 19414 all phecode
496.2 Chronic bronchitis Respiratory 1.25 1.21 – 1.29 1.7e-35 4128 26624 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.26 1.21 – 1.31 4.95e-35 3747 25467 all phecode
496.3 Bronchiectasis Respiratory 1.02 0.933 – 1.12 0.631 549 5453 all phecode
497 Bronchitis Respiratory 1.08 1.03 – 1.13 0.00275 1946 18824 all phecode
498 Acute bronchospasm Respiratory 1.23 1.12 – 1.36 2.68e-05 496 4943 all phecode
499 Cystic fibrosis Respiratory 1.06 0.89 – 1.26 0.514 151 1510 all phecode
500 Lung disease due to external agents Respiratory 1.12 1.02 – 1.23 0.0149 557 5551 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1 0.805 – 1.25 0.981 92 920 all phecode
500.2 Pneumoconiosis Respiratory 1.24 0.981 – 1.58 0.0721 78 764 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.11 1.02 – 1.21 0.0158 634 6225 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.08 0.999 – 1.16 0.0541 815 8076 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.22 1.13 – 1.32 1.78e-07 835 8243 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.08 0.983 – 1.18 0.115 595 5878 all phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 1 0.886 – 1.13 0.982 311 3084 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.12 1.06 – 1.19 2.36e-05 1638 15749 all phecode
506 Empyema and pneumothorax Respiratory 1.09 1.04 – 1.13 6.07e-05 2894 25235 all phecode
507 Pleurisy; pleural effusion Respiratory 1.12 1.07 – 1.16 1.15e-07 2916 26208 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.12 1.07 – 1.17 1.2e-06 2382 22588 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.14 1.1 – 1.18 5.98e-14 4032 29477 all phecode
509.1 Respiratory failure Respiratory 1.17 1.11 – 1.23 6.1e-10 1937 18949 all phecode
509.2 Respiratory insufficiency Respiratory 1.12 1.05 – 1.2 0.000481 1174 11679 all phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.11 1.06 – 1.17 7.04e-05 1689 16489 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.21 1.15 – 1.28 8.37e-13 1741 17249 all phecode
510 Other diseases of lung Respiratory 1.05 1.02 – 1.08 0.00293 5503 35907 all phecode
510.2 Lung transplant Respiratory 0.982 0.836 – 1.15 0.826 176 1757 all phecode
512 Other symptoms of respiratory system Respiratory 1.08 1.06 – 1.1 2.31e-13 18621 28154 all phecode
512.1 Wheezing Respiratory 1.2 1.14 – 1.28 3.64e-10 1409 13516 all phecode
512.2 Painful respiration Respiratory 1.06 1.01 – 1.11 0.00974 2309 21263 all phecode
512.3 Abnormal chest sounds Respiratory 1.01 0.892 – 1.14 0.875 291 2845 all phecode
512.7 Shortness of breath Respiratory 1.13 1.1 – 1.16 6.26e-23 10034 28081 all phecode
512.8 Cough Respiratory 1.07 1.05 – 1.1 2.12e-08 9501 28148 all phecode
512.9 Other dyspnea Respiratory 1.1 1.08 – 1.13 4.51e-16 10804 28104 all phecode
513 Respiratory abnormalities Respiratory 1.12 1.09 – 1.14 4.44e-23 12932 33822 all phecode
513.3 Hypoventilation Respiratory 1.22 1.14 – 1.32 6e-08 880 8646 all phecode
513.31 Apnea Respiratory 1.11 1 – 1.22 0.0454 462 4607 all phecode
513.32 Orthopnea Respiratory 1.3 1.13 – 1.5 0.000332 220 2160 all phecode
513.4 Hyperventilation Respiratory 1.27 1.16 – 1.4 1.12e-06 515 5124 all phecode
513.8 Disorders of diaphragm Respiratory 1.04 0.905 – 1.19 0.599 258 2557 all phecode
514 Abnormal findings examination of lungs Respiratory 1.05 1.02 – 1.08 0.00277 5365 34834 all phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 0.936 0.818 – 1.07 0.333 258 2580 all phecode
514.2 Solitary pulmonary nodule Respiratory 1.05 1.01 – 1.09 0.0258 3018 27338 all phecode
516 Abnormal sputum Respiratory 1.12 1.03 – 1.21 0.00544 735 7332 all phecode
516.1 Hemoptysis Respiratory 1.14 1.05 – 1.25 0.00312 611 6080 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.07 1.04 – 1.1 1.4e-06 6458 39057 all phecode
519.1 Tracheostomy complications Respiratory 1.25 1.07 – 1.44 0.00362 214 2136 all phecode
519.2 Respiratory complications Respiratory 1.04 0.942 – 1.16 0.409 445 4430 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.01 0.955 – 1.06 0.758 1588 15787 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.09 1.05 – 1.12 4.19e-07 4706 34489 all phecode
520 Disorders of tooth development Digestive 1 0.899 – 1.12 0.95 369 3690 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.21 1.02 – 1.42 0.0263 165 1642 all phecode
520.2 Disturbances in tooth eruption Digestive 0.918 0.796 – 1.06 0.244 218 2172 all phecode
521 Diseases of hard tissues of teeth Digestive 1.17 1.09 – 1.26 8.62e-06 898 8954 all phecode
521.1 Dental caries Digestive 1.19 1.1 – 1.28 5.83e-06 837 8349 all phecode
521.2 Dental abrasion, erosion and attrition Digestive 1.13 0.858 – 1.5 0.376 52 510 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.25 1.14 – 1.37 3.33e-06 535 5340 all phecode
522.5 Periapical abscess Digestive 1.29 1.16 – 1.42 8.15e-07 459 4583 all phecode
523 Gingival and periodontal diseases Digestive 1.17 1.08 – 1.27 9.67e-05 718 7180 all phecode
523.1 Gingivitis Digestive 1.09 0.915 – 1.3 0.331 142 1418 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.24 1.11 – 1.38 0.000155 364 3636 all phecode
523.31 Acute periodontitis Digestive 1.24 1.1 – 1.39 0.000494 311 3109 all phecode
523.32 Chronic periodontitis Digestive 1.18 0.976 – 1.43 0.0875 122 1204 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.823 0.734 – 0.924 0.000928 363 3630 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.799 0.692 – 0.922 0.00219 220 2200 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.17 1.09 – 1.25 7.17e-06 1039 10382 all phecode
525.1 Loss of teeth or edentulism Digestive 1.13 1.02 – 1.27 0.0258 374 3731 all phecode
526 Diseases of the jaws Digestive 0.945 0.906 – 0.985 0.00784 2680 26455 all phecode
526.1 Cysts of the jaws Digestive 0.853 0.746 – 0.976 0.0202 247 2470 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.787 0.684 – 0.906 0.000858 241 2383 all phecode
526.4 Temporomandibular joint disorders Digestive 0.925 0.875 – 0.979 0.00673 1504 15025 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.919 0.863 – 0.979 0.00893 1187 11858 all phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 0.901 0.832 – 0.976 0.011 741 7400 all phecode
526.5 Inflammatory conditions of jaw Digestive 1.01 0.894 – 1.15 0.839 287 2864 all phecode
526.8 Exostosis of jaw Digestive 1.05 0.784 – 1.42 0.724 53 521 all phecode
526.9 Jaw disease NOS Digestive 0.951 0.863 – 1.05 0.307 487 4867 all phecode
527 Diseases of the salivary glands Digestive 1.02 0.97 – 1.07 0.425 1781 17771 all phecode
527.1 Hypertrophy of salivary gland Digestive 0.999 0.76 – 1.31 0.992 58 579 all phecode
527.2 Sialoadenitis Digestive 1.06 0.947 – 1.18 0.327 394 3936 all phecode
527.7 Disturbance of salivary secretion Digestive 0.994 0.927 – 1.07 0.865 952 9481 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.16 1.01 – 1.33 0.0346 254 2540 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.972 0.932 – 1.01 0.194 2643 26197 all phecode
528.1 Stomatitis and mucositis Digestive 0.959 0.882 – 1.04 0.332 668 6657 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.03 0.886 – 1.19 0.709 211 2110 all phecode
528.12 Oral aphthae Digestive 0.974 0.841 – 1.13 0.72 215 2137 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.13 0.982 – 1.3 0.0892 235 2338 all phecode
528.4 Cysts of oral soft tissues Digestive 0.763 0.629 – 0.926 0.00615 124 1229 all phecode
528.41 Cyst of the salivary gland Digestive 0.87 0.68 – 1.11 0.267 77 760 all phecode
528.5 Diseases of lips Digestive 1.01 0.911 – 1.11 0.89 462 4602 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.03 0.862 – 1.24 0.714 137 1370 all phecode
528.7 Sialolithiasis Digestive 1.11 0.938 – 1.32 0.223 163 1623 all phecode
529 Diseases and other conditions of the tongue Digestive 1.11 1.03 – 1.21 0.0107 690 6878 all phecode
529.1 Glossitis Digestive 1.11 0.915 – 1.34 0.293 129 1281 all phecode
529.6 Glossodynia Digestive 1.1 0.938 – 1.3 0.236 168 1652 all phecode
530 Diseases of esophagus Digestive 1.12 1.09 – 1.14 6.83e-26 17081 27931 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.12 1.09 – 1.14 7.71e-26 16572 27931 all phecode
530.11 GERD Digestive 1.12 1.1 – 1.14 4.76e-26 16143 27929 all phecode
530.12 Ulcer of esophagus Digestive 1.11 0.994 – 1.23 0.0641 400 3983 all phecode
530.13 Barrett's esophagus Digestive 1.17 1.08 – 1.27 7.04e-05 762 7584 all phecode
530.14 Reflux esophagitis Digestive 1.1 1.04 – 1.15 0.000278 1900 17495 all phecode
530.15 Eosinophilic esophagitis Digestive 1.02 0.88 – 1.18 0.811 221 2210 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.11 1.02 – 1.2 0.0183 651 6473 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.07 0.993 – 1.15 0.0757 911 8971 all phecode
530.5 Disorders of esophageal motility Digestive 1.08 0.981 – 1.18 0.119 548 5432 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.936 0.775 – 1.13 0.494 129 1265 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.14 0.898 – 1.45 0.281 82 812 all phecode
530.9 Heartburn Digestive 1.1 1.04 – 1.16 0.00136 1519 14928 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.09 1.04 – 1.15 0.000248 2073 20617 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.04 0.929 – 1.15 0.525 391 3883 all phecode
531.2 Gastric ulcer Digestive 1.12 1.05 – 1.19 0.000326 1201 11970 all phecode
531.3 Duodenal ulcer Digestive 1.05 0.951 – 1.16 0.339 467 4640 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.07 0.991 – 1.16 0.0835 804 8018 all phecode
531.5 Gastrojejunal ulcer Digestive 1.27 1.07 – 1.52 0.00775 150 1500 all phecode
532 Dysphagia Digestive 1.1 1.07 – 1.14 4.29e-10 5585 26852 all phecode
535 Gastritis and duodenitis Digestive 1.08 1.04 – 1.12 0.000286 2799 27335 all phecode
535.1 Acute gastritis Digestive 1.14 1.07 – 1.22 2.61e-05 1178 11750 all phecode
535.2 Atrophic gastritis Digestive 0.974 0.866 – 1.09 0.658 344 3413 all phecode
535.6 Duodenitis Digestive 1.01 0.896 – 1.13 0.923 334 3337 all phecode
535.8 Other specified gastritis Digestive 0.996 0.915 – 1.08 0.93 638 6354 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.02 0.961 – 1.09 0.485 1255 12511 all phecode
536 Disorders of function of stomach Digestive 1.03 0.993 – 1.08 0.101 2911 27685 all phecode
536.3 Gastroparesis Digestive 1.08 0.999 – 1.17 0.0544 706 6901 all phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.08 0.972 – 1.2 0.152 407 4059 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.01 0.967 – 1.06 0.585 2150 21094 all phecode
537 Other disorders of stomach and duodenum Digestive 1.1 1.06 – 1.14 2.66e-06 3183 30048 all phecode
537.1 Lesions of stomach and duodenum Digestive 1.18 1 – 1.39 0.0461 173 1725 all phecode
539 Bariatric surgery Digestive 1.77 1.67 – 1.87 4.31e-82 1509 15074 all phecode
540 Appendiceal conditions Digestive 0.96 0.869 – 1.06 0.412 495 4948 all phecode
540.1 Appendicitis Digestive 0.933 0.838 – 1.04 0.201 425 4239 all phecode
540.11 Acute appendicitis Digestive 0.914 0.813 – 1.03 0.132 353 3511 all phecode
550 Abdominal hernia Digestive 1.05 1.02 – 1.08 0.00128 6768 37731 all phecode
550.1 Inguinal hernia Digestive 0.83 0.788 – 0.874 1.65e-12 1744 16488 all phecode
550.2 Diaphragmatic hernia Digestive 1.07 1.02 – 1.11 0.00187 2817 25849 all phecode
550.3 Femoral hernia Digestive 0.718 0.592 – 0.872 0.000809 131 1291 all phecode
550.4 Umbilical hernia Digestive 1.05 0.991 – 1.12 0.0985 1313 13110 all phecode
550.5 Ventral hernia Digestive 1.19 1.13 – 1.24 3.75e-13 2241 22163 all phecode
550.6 Incisional hernia Digestive 1.18 1.11 – 1.26 3.79e-08 1313 13111 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.09 1.03 – 1.15 0.00352 1536 15153 all phecode
555.1 Regional enteritis Digestive 1.13 1.06 – 1.22 0.000501 919 9095 all phecode
555.2 Ulcerative colitis Digestive 1 0.935 – 1.08 0.932 937 9315 all phecode
555.21 Ulcerative colitis (chronic) Digestive 0.943 0.859 – 1.04 0.218 537 5315 all phecode
556 Ulceration of the lower GI tract Digestive 1.11 1.01 – 1.21 0.0228 632 6267 all phecode
556.1 Ulceration of intestine Digestive 1.1 1.01 – 1.21 0.0371 551 5451 all phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 1.02 0.877 – 1.18 0.83 214 2093 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.22 1.16 – 1.28 1.74e-13 1716 16490 all phecode
557.1 Celiac disease Digestive 0.934 0.841 – 1.04 0.204 421 4026 all phecode
558 Noninfectious gastroenteritis Digestive 1.08 1.04 – 1.12 6.83e-05 3458 26408 all phecode
559 Ileostomy status Digestive 1.06 0.99 – 1.14 0.093 957 9565 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.07 1.03 – 1.11 0.00127 3004 24851 all phecode
560.1 Paralytic ileus Digestive 1.06 1.01 – 1.12 0.0299 1627 15714 all phecode
560.2 Impaction of intestine Digestive 1.09 0.975 – 1.22 0.131 387 3779 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.96 0.84 – 1.1 0.547 266 2647 all phecode
560.4 Other intestinal obstruction Digestive 1.06 1.01 – 1.12 0.022 1651 16170 all phecode
561 Symptoms involving digestive system Digestive 1.02 0.982 – 1.07 0.263 2608 21766 all phecode
562 Diverticulosis and diverticulitis Digestive 1.04 1.01 – 1.07 0.0115 6295 23431 all phecode
562.1 Diverticulosis Digestive 1.04 1.01 – 1.07 0.0137 6246 23383 all phecode
562.2 Diverticulitis Digestive 1.04 0.986 – 1.1 0.144 1611 15162 all phecode
564 Functional digestive disorders Digestive 1.06 1.04 – 1.09 5.92e-07 11411 28676 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.04 1.01 – 1.09 0.0239 3457 22266 all phecode
564.9 Personal history of diseases of digestive system Digestive 1.08 1.03 – 1.12 0.000299 3074 25861 all phecode
565 Anal and rectal conditions Digestive 0.993 0.957 – 1.03 0.721 3355 30757 all phecode
565.1 Anal and rectal polyp Digestive 0.982 0.925 – 1.04 0.561 1305 12649 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.15 1.08 – 1.22 4.51e-06 1364 13616 all phecode
568 Other disorders of peritoneum Digestive 1.16 1.1 – 1.22 4.29e-08 1705 17038 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.19 1.12 – 1.26 2.63e-08 1247 12468 all phecode
569 Other disorders of intestine Digestive 1.07 1.04 – 1.1 3.34e-07 8079 35231 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.08 0.961 – 1.22 0.188 326 3260 all phecode
569.2 Gastrointestinal complications Digestive 1.19 1.12 – 1.26 5.74e-09 1395 13933 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.14 1.11 – 1.18 1.24e-15 4610 32562 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.15 1.11 – 1.18 1.81e-15 4342 32234 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.13 1.06 – 1.21 0.000235 1018 10095 all phecode
571.6 Primary biliary cirrhosis Digestive 1.03 0.878 – 1.21 0.725 179 1790 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.11 1.03 – 1.19 0.00345 950 9498 all phecode
571.81 Portal hypertension Digestive 1.08 0.986 – 1.18 0.0995 573 5730 all phecode
572 Ascites (non malignant) Digestive 1.08 1.03 – 1.13 0.00155 2278 22675 all phecode
573 Other disorders of liver Digestive 1.09 1.05 – 1.12 8.61e-08 5599 33620 all phecode
573.1 Chronic passive congestion of liver Digestive 1.25 1.05 – 1.5 0.0147 136 1359 all phecode
573.2 Liver replaced by transplant Digestive 1.1 0.967 – 1.25 0.147 292 2920 all phecode
573.3 Hepatomegaly Digestive 1.18 1.07 – 1.3 0.00122 470 4700 all phecode
573.4 Acute and subacute necrosis of liver Digestive 1.01 0.895 – 1.14 0.861 316 3149 all phecode
573.5 Jaundice (not of newborn) Digestive 1.06 0.993 – 1.14 0.0785 958 9496 all phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.06 1.02 – 1.11 0.00304 2756 26470 all phecode
573.7 Abnormal results of function study of liver Digestive 1.05 1.01 – 1.09 0.0266 3018 27774 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.05 1.01 – 1.08 0.00465 4679 33866 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.13 1.08 – 1.17 2.14e-09 3177 30809 all phecode
574.1 Cholelithiasis Digestive 1.13 1.08 – 1.17 4.23e-09 2924 28874 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.24 1.1 – 1.4 0.000295 342 3412 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.08 0.988 – 1.19 0.0898 553 5501 all phecode
574.2 Calculus of bile duct Digestive 1.06 0.982 – 1.14 0.139 852 8503 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.17 1.09 – 1.26 4.05e-05 822 8181 all phecode
575 Other biliary tract disease Digestive 1.05 1 – 1.1 0.0327 2266 22555 all phecode
575.1 Cholangitis Digestive 1.02 0.911 – 1.14 0.726 354 3530 all phecode
575.2 Obstruction of bile duct Digestive 1.15 1.05 – 1.25 0.00204 621 6201 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.948 0.818 – 1.1 0.476 207 2063 all phecode
575.7 Other disorders of gallbladder Digestive 1.03 0.963 – 1.11 0.357 939 9382 all phecode
575.8 Other disorders of biliary tract Digestive 1.06 0.997 – 1.13 0.0597 1154 11523 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.02 0.895 – 1.17 0.741 260 2600 all phecode
577 Diseases of pancreas Digestive 1.07 1.02 – 1.12 0.00277 2225 22106 all phecode
577.1 Acute pancreatitis Digestive 1.14 1.07 – 1.21 4.21e-05 1212 12110 all phecode
577.2 Chronic pancreatitis Digestive 1.17 1.06 – 1.29 0.00154 495 4950 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.01 0.918 – 1.11 0.875 570 5601 all phecode
578 Gastrointestinal hemorrhage Digestive 1.05 1.01 – 1.08 0.00753 4554 37045 all phecode
578.1 Hematemesis Digestive 1.16 1.05 – 1.28 0.00356 485 4842 all phecode
578.2 Blood in stool Digestive 1.07 1.03 – 1.12 0.000786 2743 26554 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.02 0.978 – 1.07 0.316 2210 21750 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.08 1.02 – 1.14 0.00616 1562 15345 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.11 1.07 – 1.15 4.89e-10 4431 34209 all phecode
579.2 Splenomegaly Digestive 1.19 1.1 – 1.29 1.32e-05 730 7262 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.05 0.996 – 1.12 0.0684 1410 13877 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.24 1.18 – 1.31 2e-16 1881 15516 all phecode
580.1 Glomerulonephritis Genitourinary 1.22 1.09 – 1.36 0.00036 401 3992 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.12 0.936 – 1.34 0.217 146 1440 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.51 1.23 – 1.85 6.44e-05 114 1128 all phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.05 0.802 – 1.37 0.73 61 600 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.28 1.13 – 1.46 0.000183 277 2760 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.2 1.04 – 1.38 0.0128 221 2193 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.26 1.19 – 1.33 1.37e-14 1502 11930 all phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.34 1.24 – 1.44 5.32e-15 992 7228 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.16 1.07 – 1.26 0.000469 683 6612 all phecode
580.4 Renal sclerosis, NOS Genitourinary 1.23 1.09 – 1.39 0.000521 340 3400 all phecode
585 Renal failure Genitourinary 1.19 1.16 – 1.23 1.84e-36 7470 32340 all phecode
585.1 Acute renal failure Genitourinary 1.2 1.16 – 1.25 5.84e-26 4265 27230 all phecode
585.2 Renal failure NOS Genitourinary 1.22 1.13 – 1.32 2.13e-07 832 8162 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.21 1.17 – 1.25 2.06e-33 5580 29470 all phecode
585.31 Renal dialysis Genitourinary 1.23 1.13 – 1.33 5.64e-07 747 7423 all phecode
585.32 End stage renal disease Genitourinary 1.29 1.2 – 1.38 7.76e-13 1007 9783 all phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.24 1.19 – 1.29 4.91e-25 3209 21312 all phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.26 1.18 – 1.35 6.81e-11 977 9190 all phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.24 1.16 – 1.32 2.88e-11 1227 11191 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.12 1.09 – 1.15 1.65e-16 7628 34189 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.13 1.01 – 1.27 0.0334 349 3480 all phecode
586.11 Small kidney Genitourinary 1.18 1.02 – 1.36 0.0263 210 2093 all phecode
586.12 Vesicoureteral reflux Genitourinary 1.08 0.893 – 1.29 0.443 136 1360 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.05 0.987 – 1.11 0.13 1381 12912 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.2 1.03 – 1.4 0.0179 187 1862 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.03 0.977 – 1.08 0.29 1821 17115 all phecode
587 Kidney replaced by transpant Genitourinary 1.17 1.08 – 1.26 6.62e-05 819 8134 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.22 1.13 – 1.3 3.96e-08 976 9389 all phecode
588.1 Renal osteodystrophy Genitourinary 1.16 1.02 – 1.32 0.0265 290 2900 all phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.23 1.13 – 1.33 4.3e-07 755 7275 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.18 1.1 – 1.27 1.69e-06 1007 9834 all phecode
590 Pyelonephritis Genitourinary 1.14 1.08 – 1.2 7.05e-06 1461 14350 all phecode
591 Urinary tract infection Genitourinary 1.04 1.01 – 1.06 0.00516 9873 32513 all phecode
592 Cystitis and urethritis Genitourinary 1.01 0.97 – 1.05 0.622 3038 24207 all phecode
592.1 Cystitis Genitourinary 1.02 0.975 – 1.06 0.46 2880 23279 all phecode
592.11 Acute cystitis Genitourinary 1.01 0.963 – 1.07 0.585 1783 16452 all phecode
592.12 Chronic cystitis Genitourinary 0.987 0.859 – 1.14 0.859 239 2343 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.955 0.86 – 1.06 0.386 431 4310 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.952 0.821 – 1.1 0.511 210 2093 all phecode
593 Hematuria Genitourinary 1.05 1.02 – 1.08 0.00292 4859 32063 all phecode
593.1 Gross hematuria Genitourinary 1.06 1 – 1.12 0.038 1585 14824 all phecode
593.2 Microscopic hematuria Genitourinary 1.04 0.973 – 1.11 0.247 1049 10301 all phecode
594 Urinary calculus Genitourinary 1.08 1.05 – 1.11 1.7e-07 6707 38209 all phecode
594.1 Calculus of kidney Genitourinary 1.08 1.05 – 1.11 3.12e-07 6273 38051 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.12 1 – 1.25 0.0427 366 3638 all phecode
594.3 Calculus of ureter Genitourinary 1.05 0.993 – 1.12 0.0847 1361 13561 all phecode
594.8 Renal colic Genitourinary 1.06 0.943 – 1.19 0.335 356 3560 all phecode
595 Hydronephrosis Genitourinary 1.07 1.02 – 1.13 0.00812 1670 16658 all phecode
596 Other disorders of bladder Genitourinary 1.01 0.972 – 1.05 0.593 3074 28020 all phecode
596.1 Bladder neck obstruction Genitourinary 1.01 0.904 – 1.12 0.897 400 3942 all phecode
596.5 Functional disorders of bladder Genitourinary 1 0.95 – 1.06 0.964 1719 17049 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.97 0.912 – 1.03 0.34 1211 11998 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.941 0.866 – 1.02 0.152 661 6537 all phecode
597.2 Urinary complications NEC Genitourinary 1.04 0.969 – 1.11 0.304 1049 10479 all phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.08 0.928 – 1.27 0.307 189 1873 all phecode
598 Abnormal findings on examination of urine Genitourinary 1 0.831 – 1.21 0.988 138 1356 all phecode
598.4 Other cells and casts in urine Genitourinary 0.987 0.809 – 1.2 0.899 122 1192 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.99 – 1.03 0.316 14168 30681 all phecode
599.1 Urinary obstruction Genitourinary 0.875 0.807 – 0.948 0.00112 728 6861 all phecode
599.2 Retention of urine Genitourinary 1.01 0.973 – 1.04 0.745 5034 28305 all phecode
599.3 Dysuria Genitourinary 1 0.968 – 1.04 0.947 4397 27849 all phecode
599.4 Urinary incontinence Genitourinary 1.03 0.999 – 1.06 0.0606 5599 26960 all phecode
599.5 Frequency of urination and polyuria Genitourinary 0.996 0.966 – 1.03 0.805 5498 28723 all phecode
599.6 Oliguria and anuria Genitourinary 1.13 1.04 – 1.24 0.00646 599 5902 all phecode
599.7 Urethral discharge Genitourinary 1.06 0.873 – 1.28 0.562 118 1175 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.01 0.976 – 1.04 0.686 5446 27963 all phecode
599.9 Other abnormality of urination Genitourinary 0.974 0.936 – 1.01 0.196 3041 24877 all phecode
600 Hyperplasia of prostate Genitourinary 0.946 0.909 – 0.984 0.00601 4063 11364 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.981 0.918 – 1.05 0.578 1044 9665 all phecode
601.1 Prostatitis Genitourinary 0.855 0.776 – 0.943 0.00166 477 4596 all phecode
601.11 Acute prostatitis Genitourinary 0.949 0.781 – 1.15 0.604 124 1200 all phecode
601.12 Chronic prostatitis Genitourinary 0.963 0.774 – 1.2 0.733 95 943 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.06 0.949 – 1.18 0.318 389 3822 all phecode
601.4 Balanoposthitis Genitourinary 1.01 0.831 – 1.22 0.943 127 1224 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.18 0.997 – 1.39 0.0536 161 1591 all phecode
602 Other disorders of prostate Genitourinary 0.918 0.818 – 1.03 0.146 361 3399 all phecode
602.3 Dysplasia of prostate Genitourinary 0.965 0.753 – 1.24 0.78 77 730 all phecode
603 Other disorders of testis Genitourinary 0.989 0.894 – 1.09 0.825 440 4354 all phecode
603.1 Hydrocele Genitourinary 1.01 0.892 – 1.14 0.898 293 2882 all phecode
603.2 Spermatocele Genitourinary 0.846 0.716 – 0.999 0.0488 156 1539 all phecode
604 Disorders of penis Genitourinary 0.963 0.888 – 1.04 0.363 685 6748 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.28 1.09 – 1.52 0.00314 155 1540 all phecode
604.3 Peyronie's disease Genitourinary 0.876 0.758 – 1.01 0.0711 215 2132 all phecode
605 Erectile dysfunction [ED] Genitourinary 0.967 0.931 – 1.01 0.0924 3776 12700 all phecode
608 Other disorders of male genital organs Genitourinary 0.976 0.925 – 1.03 0.373 1645 13758 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.872 0.787 – 0.967 0.00913 424 4196 all phecode
609.1 Infertility, male Genitourinary 0.912 0.808 – 1.03 0.136 302 2992 all phecode
609.11 Azoospermia and oligospermia Genitourinary 1.14 0.917 – 1.41 0.24 95 950 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.755 0.636 – 0.897 0.00141 154 1519 all phecode
610 Benign mammary dysplasias Genitourinary 0.919 0.884 – 0.955 1.5e-05 3683 16548 all phecode
610.1 Cystic mastopathy Genitourinary 0.928 0.878 – 0.98 0.00716 1633 14191 all phecode
610.2 Fibroadenosis of breast Genitourinary 0.853 0.647 – 1.12 0.259 60 600 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.901 0.864 – 0.941 1.98e-06 2837 16430 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.933 0.877 – 0.992 0.0278 1269 12191 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.909 0.881 – 0.938 2.77e-09 6067 18690 all phecode
611.1 Abnormal mammogram Genitourinary 0.894 0.863 – 0.925 1.54e-10 4980 16120 all phecode
611.11 Mammographic microcalcification Genitourinary 0.824 0.772 – 0.881 9.81e-09 1122 10394 all phecode
611.3 Lump or mass in breast Genitourinary 0.899 0.865 – 0.934 5.69e-08 3549 18572 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.964 0.901 – 1.03 0.291 1051 10425 all phecode
612.1 Galactorrhea Genitourinary 0.993 0.828 – 1.19 0.938 139 1390 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.01 0.937 – 1.09 0.76 800 7962 all phecode
612.3 Congenital anomalies of breast Genitourinary 0.571 0.442 – 0.739 2.09e-05 83 810 all phecode
613 Other nonmalignant breast conditions Genitourinary 0.963 0.929 – 0.999 0.0437 3897 22072 all phecode
613.1 Inflammatory disease of breast Genitourinary 0.97 0.888 – 1.06 0.499 593 5874 all phecode
613.5 Mastodynia Genitourinary 0.983 0.931 – 1.04 0.524 1675 16203 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.905 0.841 – 0.974 0.00813 883 8754 all phecode
613.8 Other specified disorders of breast Genitourinary 0.886 0.824 – 0.953 0.00116 932 9248 all phecode
613.9 Breast disorder NOS Genitourinary 0.935 0.883 – 0.99 0.0208 1465 14174 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.994 0.958 – 1.03 0.772 3715 19647 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1 0.892 – 1.13 0.947 337 3370 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.05 0.953 – 1.16 0.316 478 4773 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.19 0.95 – 1.49 0.131 94 933 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.938 0.8 – 1.1 0.434 186 1842 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.01 0.881 – 1.16 0.879 246 2460 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.04 0.876 – 1.23 0.662 165 1639 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.988 0.949 – 1.03 0.551 3180 19539 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.08 0.942 – 1.24 0.271 264 2640 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.973 0.932 – 1.02 0.208 2732 18924 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.13 0.936 – 1.37 0.2 132 1311 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.15 0.99 – 1.33 0.0668 225 2244 all phecode
615 Endometriosis Genitourinary 0.991 0.938 – 1.05 0.741 1585 14666 all phecode
618 Genital prolapse Genitourinary 0.954 0.909 – 1 0.0568 2079 17915 all phecode
618.1 Prolapse of vaginal walls Genitourinary 0.917 0.865 – 0.972 0.00351 1408 13456 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.913 0.831 – 1 0.06 542 5390 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.913 0.805 – 1.04 0.157 317 3162 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.06 0.957 – 1.18 0.262 441 4394 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.992 0.961 – 1.02 0.622 5728 18687 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.02 0.96 – 1.09 0.497 1233 12082 all phecode
619.2 Disorders of uterus, NEC Genitourinary 0.941 0.86 – 1.03 0.18 591 5897 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.96 0.87 – 1.06 0.421 483 4823 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.985 0.943 – 1.03 0.516 2525 18404 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.05 0.983 – 1.12 0.149 1189 11717 all phecode
620 Dysplasia of female genital organs Genitourinary 1.06 0.95 – 1.18 0.302 395 3950 all phecode
620.1 Dysplasia of cervix Genitourinary 1.04 0.886 – 1.22 0.626 178 1780 all phecode
621 Endometrial hyperplasia Genitourinary 1.09 0.979 – 1.21 0.116 437 4370 all phecode
622 Polyp of female genital organs Genitourinary 0.95 0.897 – 1.01 0.0829 1449 14264 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.986 0.924 – 1.05 0.66 1132 11189 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.867 0.782 – 0.963 0.00737 445 4444 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.04 0.968 – 1.13 0.259 824 8165 all phecode
624 Symptoms involving female genital tract Genitourinary 0.977 0.921 – 1.04 0.446 1348 12518 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.907 0.783 – 1.05 0.196 216 2155 all phecode
624.2 Atrophy of female genital tract Genitourinary 1.08 0.814 – 1.43 0.597 64 615 all phecode
624.9 stress incontinence, female Genitourinary 1.01 0.96 – 1.06 0.711 1935 15408 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.979 0.948 – 1.01 0.19 5653 17303 all phecode
625.1 Dyspareunia Genitourinary 0.921 0.866 – 0.98 0.00893 1267 12474 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.993 0.962 – 1.03 0.685 5940 15585 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.995 0.96 – 1.03 0.81 4315 14604 all phecode
626.11 Absent or infrequent menstruation Genitourinary 1.02 0.956 – 1.09 0.504 1062 8531 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.02 0.967 – 1.07 0.521 2097 11991 all phecode
626.13 Irregular menstrual cycle Genitourinary 1.01 0.958 – 1.06 0.759 1957 12265 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.962 0.897 – 1.03 0.28 970 8996 all phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.968 0.868 – 1.08 0.564 394 3789 all phecode
626.2 Dysmenorrhea Genitourinary 1.05 0.984 – 1.11 0.148 1373 9857 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.97 0.86 – 1.09 0.614 336 3308 all phecode
626.8 Infertility, female Genitourinary 0.968 0.896 – 1.04 0.401 817 6741 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.929 0.896 – 0.963 5.85e-05 4560 14557 all phecode
627.1 Postmenopausal bleeding Genitourinary 0.944 0.884 – 1.01 0.0852 1146 10338 all phecode
627.2 Symptomatic menopause Genitourinary 0.915 0.877 – 0.954 3.93e-05 3017 13763 all phecode
627.21 Symptomatic artificial menopause Genitourinary 0.868 0.724 – 1.04 0.124 152 1514 all phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.753 0.669 – 0.848 2.74e-06 356 3513 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.888 0.828 – 0.953 0.000959 997 9484 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.921 0.821 – 1.03 0.157 361 3580 all phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.895 0.792 – 1.01 0.0785 309 3082 all phecode
628 Ovarian cyst Genitourinary 1.01 0.956 – 1.06 0.825 1945 13838 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.98 0.909 – 1.06 0.592 826 8047 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.92 0.806 – 1.05 0.216 273 2715 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.979 0.802 – 1.19 0.833 117 1170 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.869 0.792 – 0.953 0.00276 563 5309 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.86 0.767 – 0.964 0.00958 370 3629 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.842 0.741 – 0.957 0.00839 288 2850 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.943 0.882 – 1.01 0.088 1080 7870 all phecode
636.1 Threatened premature labor Pregnancy Complications 0.955 0.855 – 1.07 0.414 380 3799 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.967 0.849 – 1.1 0.61 288 2868 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.947 0.854 – 1.05 0.299 441 4365 all phecode
636.8 Cervical incompetence Pregnancy Complications 1.13 0.891 – 1.44 0.308 77 770 all phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.08 0.858 – 1.36 0.519 85 850 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.03 0.938 – 1.12 0.57 585 5725 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.02 0.898 – 1.15 0.789 302 3013 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.08 0.942 – 1.24 0.268 252 2506 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.04 0.855 – 1.26 0.7 119 1190 all phecode
644 Anemia during pregnancy Pregnancy Complications 1 0.868 – 1.16 0.955 224 2224 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.98 0.909 – 1.06 0.606 855 6531 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.935 0.808 – 1.08 0.371 211 2093 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.01 0.874 – 1.16 0.906 222 2213 all phecode
647.3 Major puerperal infection Pregnancy Complications 1.15 0.878 – 1.49 0.318 65 650 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.964 0.905 – 1.03 0.257 1275 8010 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.01 0.928 – 1.1 0.802 649 5687 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.982 0.897 – 1.07 0.685 587 5463 all phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.967 0.83 – 1.13 0.672 207 2055 all phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 0.902 0.775 – 1.05 0.185 204 2040 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.931 0.88 – 0.984 0.0118 1624 10064 all phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 0.948 0.868 – 1.04 0.236 616 5533 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.987 0.917 – 1.06 0.732 898 7014 all phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 1.12 0.859 – 1.45 0.408 66 660 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.936 0.869 – 1.01 0.0801 887 6802 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.06 0.924 – 1.22 0.394 236 2351 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.04 0.879 – 1.24 0.633 158 1580 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.806 0.688 – 0.946 0.00817 184 1814 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.14 1.1 – 1.17 3.11e-19 6500 38394 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.03 0.972 – 1.1 0.288 1256 11462 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.13 1.05 – 1.21 0.00062 1007 9981 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.16 1.11 – 1.22 3.34e-10 2123 19952 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.17 1.12 – 1.23 1.76e-11 2252 20944 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.17 1.11 – 1.23 1.66e-09 1820 16893 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.21 1.14 – 1.27 2.05e-11 1572 15588 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.09 1.04 – 1.14 0.00033 2257 21750 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.13 1.03 – 1.24 0.00956 558 5504 all phecode
686.2 Impetigo Dermatologic 1.09 0.975 – 1.21 0.132 414 4117 all phecode
686.3 Pilonidal cyst Dermatologic 1.08 0.909 – 1.27 0.395 160 1594 all phecode
686.4 Pyogenic granuloma Dermatologic 1.03 0.869 – 1.22 0.739 158 1570 all phecode
686.5 Pyoderma Dermatologic 1.21 0.924 – 1.58 0.166 63 630 all phecode
687 Symptoms affecting skin Dermatologic 0.991 0.94 – 1.05 0.747 1690 16343 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.992 0.966 – 1.02 0.581 7007 34623 all phecode
687.3 Changes in skin texture Dermatologic 1.14 1.03 – 1.27 0.0129 415 4121 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.05 1.02 – 1.08 0.000676 6375 34216 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.937 0.914 – 0.96 1.3e-07 9311 37335 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.907 0.879 – 0.936 1.42e-09 5184 31581 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.907 0.879 – 0.936 1.46e-09 5174 31553 all phecode
691 Congenital anomalies of skin Dermatologic 0.99 0.903 – 1.09 0.834 541 5337 all phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 1.17 0.893 – 1.53 0.255 62 613 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.912 0.867 – 0.959 0.000332 1861 17936 all phecode
694.1 Vitiligo Dermatologic 1.05 0.874 – 1.26 0.597 137 1347 all phecode
694.2 Other dyschromia Dermatologic 0.906 0.859 – 0.956 0.000277 1674 16183 all phecode
694.3 Vascular disorders of skin Dermatologic 0.98 0.768 – 1.25 0.873 82 819 all phecode
695 Erythematous conditions Dermatologic 1.01 0.98 – 1.05 0.431 4120 30247 all phecode
695.1 Toxic erythema Dermatologic 1.22 0.936 – 1.58 0.143 70 688 all phecode
695.2 Bullous dermatoses Dermatologic 0.989 0.781 – 1.25 0.927 85 805 all phecode
695.3 Rosacea Dermatologic 0.903 0.858 – 0.951 0.000102 1816 17663 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.03 0.947 – 1.12 0.498 672 6686 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.09 0.95 – 1.25 0.22 247 2437 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.02 0.934 – 1.11 0.695 637 6337 all phecode
695.7 Prurigo and Lichen Dermatologic 0.981 0.899 – 1.07 0.677 605 5986 all phecode
695.8 Other specified erythematous conditions Dermatologic 1.14 1.06 – 1.23 8e-04 812 7980 all phecode
695.81 Erythema nodosum Dermatologic 0.859 0.647 – 1.14 0.296 55 550 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.16 1.07 – 1.26 0.000483 679 6756 all phecode
696 Psoriasis and related disorders Dermatologic 1.04 0.984 – 1.11 0.155 1401 13832 all phecode
696.3 Pityriasis Dermatologic 0.867 0.698 – 1.08 0.198 92 904 all phecode
696.4 Psoriasis Dermatologic 1.07 1 – 1.13 0.0375 1311 12976 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.05 0.986 – 1.12 0.129 1200 11867 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.03 0.908 – 1.18 0.611 282 2810 all phecode
697 Sarcoidosis Dermatologic 1.07 0.948 – 1.2 0.286 333 3330 all phecode
698 Pruritus and related conditions Dermatologic 1.01 0.966 – 1.06 0.618 2254 21889 all phecode
700 Corns and callosities Dermatologic 1.04 0.982 – 1.11 0.175 1373 10894 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.998 0.972 – 1.02 0.855 7651 38050 all phecode
701.1 Keratoderma, acquired Dermatologic 0.994 0.907 – 1.09 0.891 567 5524 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.923 0.881 – 0.966 0.000679 2184 21550 all phecode
701.3 Circumscribed scleroderma Dermatologic 0.953 0.869 – 1.04 0.304 571 5660 all phecode
701.4 Keloid scar Dermatologic 0.973 0.889 – 1.06 0.555 578 5716 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.08 0.973 – 1.2 0.145 400 3982 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.89 0.865 – 0.916 1.14e-15 6956 29525 all phecode
702.1 Actinic keratosis Dermatologic 0.861 0.831 – 0.892 6.12e-17 4171 26529 all phecode
702.2 Seborrheic keratosis Dermatologic 0.882 0.855 – 0.91 1.79e-15 5480 31552 all phecode
702.4 Degenerative skin disorders Dermatologic 1.08 0.856 – 1.36 0.521 86 832 all phecode
703 Diseases of nail, NOS Dermatologic 1.05 0.992 – 1.1 0.0978 1650 14562 all phecode
703.1 Ingrowing nail Dermatologic 1.04 0.971 – 1.12 0.252 920 8597 all phecode
704 Diseases of hair and hair follicles Dermatologic 0.968 0.931 – 1.01 0.104 3118 29542 all phecode
704.1 Alopecia Dermatologic 0.942 0.889 – 0.999 0.045 1408 13871 all phecode
704.11 Alopecia Areata Dermatologic 0.856 0.678 – 1.08 0.193 82 811 all phecode
704.12 Telogen effluvium Dermatologic 0.812 0.616 – 1.07 0.14 63 615 all phecode
704.2 Hirsutism Dermatologic 1.35 1.19 – 1.53 2.42e-06 299 2946 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.969 0.92 – 1.02 0.229 1752 17189 all phecode
705 Disorders of sweat glands Dermatologic 1.16 1.07 – 1.27 0.00073 603 6012 all phecode
705.1 Dyshidrosis Dermatologic 1.05 0.88 – 1.25 0.587 154 1540 all phecode
705.3 Hidradenitis Dermatologic 1.38 1.2 – 1.59 7.86e-06 245 2440 all phecode
705.8 Hyperhidrosis Dermatologic 1.01 0.944 – 1.08 0.825 1112 10986 all phecode
706 Diseases of sebaceous glands Dermatologic 0.928 0.902 – 0.955 4.21e-07 5995 39748 all phecode
706.1 Acne Dermatologic 0.864 0.828 – 0.902 2.96e-11 2594 22570 all phecode
706.2 Sebaceous cyst Dermatologic 0.946 0.908 – 0.986 0.0085 2814 26819 all phecode
706.3 Seborrhea Dermatologic 0.755 0.572 – 0.996 0.0467 59 582 all phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.977 0.926 – 1.03 0.396 1684 15289 all phecode
707 Chronic ulcer of skin Dermatologic 1.15 1.11 – 1.2 8.64e-12 2871 26816 all phecode
707.1 Decubitus ulcer Dermatologic 1.13 1.05 – 1.22 0.00127 825 8119 all phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.25 1.17 – 1.33 2.14e-11 1108 9992 all phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1.13 1.07 – 1.2 5.33e-06 1641 16172 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.983 0.929 – 1.04 0.551 1477 14427 all phecode
709.2 Sicca syndrome Dermatologic 1.02 0.924 – 1.12 0.727 505 4986 all phecode
709.3 Systemic sclerosis Dermatologic 0.829 0.718 – 0.956 0.00997 224 2209 all phecode
709.5 Dermatomyositis Dermatologic 0.995 0.803 – 1.23 0.964 92 892 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.01 0.802 – 1.28 0.913 90 892 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.01 0.937 – 1.08 0.857 917 9089 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.18 1.11 – 1.25 2e-07 1254 12103 all phecode
710.1 Osteomyelitis Musculoskeletal 1.18 1.11 – 1.26 2.83e-07 1203 11636 all phecode
710.11 Acute osteomyelitis Musculoskeletal 1.31 1.19 – 1.43 1.08e-08 590 5708 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.19 1.09 – 1.31 0.00025 531 5163 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.19 1.12 – 1.27 9.14e-08 1153 11149 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.04 0.93 – 1.15 0.52 410 4099 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.11 0.974 – 1.26 0.119 290 2900 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.28 1.08 – 1.52 0.00456 178 1776 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.13 1 – 1.28 0.043 314 3028 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.18 1.01 – 1.39 0.0401 194 1824 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.13 1.07 – 1.18 1.75e-06 2086 18159 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.16 1.1 – 1.22 1.09e-07 1670 15087 all phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.05 0.822 – 1.35 0.686 77 767 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.12 1.05 – 1.19 0.000462 1209 11967 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.16 1.02 – 1.33 0.0231 262 2611 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.2 1.04 – 1.39 0.0126 219 2182 all phecode
716 Other arthropathies Musculoskeletal 1.12 1.09 – 1.14 2.5e-22 13482 31305 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.01 0.86 – 1.18 0.927 192 1920 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.934 0.775 – 1.12 0.471 131 1293 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.12 1.09 – 1.14 1.41e-22 13410 31294 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.979 0.855 – 1.12 0.761 261 2565 all phecode
720 Spinal stenosis Musculoskeletal 1.1 1.06 – 1.14 1.3e-07 3958 28539 all phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1.12 1.07 – 1.16 2.16e-07 2872 23656 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1.06 1.03 – 1.09 0.000131 5509 32391 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.06 1.02 – 1.09 0.000624 5153 31896 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.11 1.03 – 1.2 0.00491 867 8629 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.24 1.08 – 1.42 0.0016 262 2600 all phecode
722 Intervertebral disc disorders Musculoskeletal 1.09 1.06 – 1.12 1.02e-09 6284 34317 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.08 1.04 – 1.12 6.57e-05 3591 31411 all phecode
722.3 Schmorl's nodes Musculoskeletal 1.07 0.879 – 1.31 0.493 126 1248 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.09 1.05 – 1.13 2.38e-06 3957 30744 all phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.1 0.996 – 1.21 0.0591 515 5140 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.07 0.96 – 1.19 0.219 397 3968 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.07 1.02 – 1.13 0.00633 1932 19288 all phecode
723 Other disorders of cervical region Musculoskeletal 0.995 0.928 – 1.07 0.887 952 9495 all phecode
723.1 Torticollis Musculoskeletal 1.01 0.884 – 1.16 0.87 254 2522 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.05 1.02 – 1.09 0.00378 4130 31954 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.05 1 – 1.1 0.0361 2307 21902 all phecode
724.2 Disorders of coccyx Musculoskeletal 0.958 0.862 – 1.07 0.428 426 4215 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.14 1.06 – 1.23 0.000331 931 9295 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.06 1 – 1.12 0.0485 1412 14087 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.974 0.951 – 0.998 0.0348 9917 30176 all phecode
726.1 Enthesopathy Musculoskeletal 0.97 0.944 – 0.996 0.0245 7507 30106 all phecode
726.2 Synoviopathy Musculoskeletal 1.01 0.94 – 1.08 0.869 1015 9987 all phecode
726.3 Bursitis Musculoskeletal 0.947 0.9 – 0.997 0.0374 1829 16722 all phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.985 0.925 – 1.05 0.632 1193 11485 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.993 0.966 – 1.02 0.586 7425 30105 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1 0.964 – 1.04 0.864 3092 24998 all phecode
727.2 Bursitis disorders Musculoskeletal 0.992 0.89 – 1.1 0.878 419 4112 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.959 0.905 – 1.02 0.157 1400 13621 all phecode
727.5 Rupture of synovium Musculoskeletal 1.15 1.04 – 1.27 0.00616 480 4672 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.977 0.935 – 1.02 0.312 2461 21948 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.998 0.913 – 1.09 0.969 591 5893 all phecode
727.8 Plica syndrome Musculoskeletal 0.859 0.716 – 1.03 0.104 130 1264 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.02 0.991 – 1.06 0.162 4546 29473 all phecode
728.1 Muscular calcification and ossification Musculoskeletal 1.09 0.868 – 1.37 0.454 85 843 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.905 0.8 – 1.02 0.114 297 2949 all phecode
728.7 Fasciitis Musculoskeletal 0.974 0.934 – 1.02 0.211 2814 23463 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.822 0.739 – 0.915 0.000318 419 4138 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.12 1.08 – 1.16 7.56e-10 3642 27471 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.06 0.831 – 1.36 0.622 74 726 all phecode
729.3 Panniculitis Musculoskeletal 1.2 0.986 – 1.46 0.0686 119 1174 all phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 0.907 0.705 – 1.17 0.446 67 664 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.14 0.981 – 1.31 0.0881 210 2091 all phecode
732 Osteochondropathies Musculoskeletal 1.1 0.983 – 1.23 0.0968 361 3604 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.18 1.02 – 1.38 0.0306 198 1969 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.986 0.783 – 1.24 0.901 90 882 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.914 0.883 – 0.946 2.31e-07 4543 26941 all phecode
733.2 Cyst of bone Musculoskeletal 0.938 0.803 – 1.1 0.422 190 1900 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.973 0.885 – 1.07 0.574 518 5160 all phecode
733.6 Costochondritis Musculoskeletal 0.968 0.862 – 1.09 0.585 357 3562 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.06 0.98 – 1.14 0.154 822 8205 all phecode
733.9 Chondromalacia Musculoskeletal 0.957 0.77 – 1.19 0.691 96 960 all phecode
735 Acquired foot deformities Musculoskeletal 0.96 0.925 – 0.997 0.0335 3417 29622 all phecode
735.1 Flat foot Musculoskeletal 0.976 0.896 – 1.06 0.589 620 6092 all phecode
735.2 Acquired toe deformities Musculoskeletal 0.963 0.906 – 1.02 0.221 1323 11983 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.97 0.898 – 1.05 0.447 825 7494 all phecode
735.23 Hallux rigidus Musculoskeletal 0.959 0.861 – 1.07 0.444 405 4005 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.921 0.871 – 0.975 0.00452 1470 14295 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.982 0.943 – 1.02 0.395 2763 26555 all phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.935 0.761 – 1.15 0.522 104 1033 all phecode
736.2 Acquired deformities of finger Musculoskeletal 0.884 0.761 – 1.03 0.104 215 2142 all phecode
736.3 Acquired deformities of hip Musculoskeletal 1.12 0.849 – 1.49 0.412 60 590 all phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.972 0.864 – 1.09 0.637 325 3247 all phecode
736.5 Acquired deformities of knee Musculoskeletal 0.957 0.837 – 1.09 0.516 246 2460 all phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.996 0.887 – 1.12 0.946 339 3365 all phecode
737 Curvature of spine Musculoskeletal 0.941 0.89 – 0.994 0.0286 1566 15543 all phecode
737.1 Kyphosis (acquired) Musculoskeletal 1.01 0.915 – 1.12 0.826 479 4748 all phecode
737.2 Lordosis (acquired) Musculoskeletal 1.29 1 – 1.67 0.0499 70 700 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.919 0.863 – 0.979 0.0085 1203 11982 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.01 0.964 – 1.05 0.757 2443 24187 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.11 1.04 – 1.19 0.00235 1057 10542 all phecode
739 Contracture of joint Musculoskeletal 0.958 0.877 – 1.05 0.332 621 6207 all phecode
740 Osteoarthrosis Musculoskeletal 1.13 1.1 – 1.15 8.11e-29 16169 30268 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.09 1.06 – 1.12 1.18e-08 7005 27422 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.08 1.05 – 1.11 9.08e-07 6176 26155 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.1 1.02 – 1.2 0.0197 713 7116 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.06 0.998 – 1.12 0.0595 1609 12092 all phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 1.11 0.989 – 1.24 0.0754 373 3586 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.14 1.11 – 1.16 9.07e-31 15497 30141 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.01 0.988 – 1.04 0.316 8555 35884 all phecode
741.1 Ankylosis of joint Musculoskeletal 0.936 0.815 – 1.07 0.347 245 2445 all phecode
741.2 Stiffness of joint Musculoskeletal 0.938 0.882 – 0.997 0.0394 1268 12594 all phecode
741.3 Difficulty in walking Musculoskeletal 1.09 1.05 – 1.14 6.01e-05 2558 23116 all phecode
741.4 Joint effusions Musculoskeletal 1.01 0.969 – 1.06 0.586 2493 24199 all phecode
741.5 Hemarthrosis Musculoskeletal 0.963 0.769 – 1.21 0.744 94 937 all phecode
741.6 Villonodular synovitis Musculoskeletal 0.859 0.66 – 1.12 0.26 68 666 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.988 0.955 – 1.02 0.461 4404 33771 all phecode
742.1 Loose body in joint Musculoskeletal 1.16 0.974 – 1.37 0.0973 156 1554 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.894 0.788 – 1.01 0.0823 280 2792 all phecode
742.8 Articular cartilage disorder Musculoskeletal 0.955 0.832 – 1.1 0.513 245 2450 all phecode
742.9 Other derangement of joint Musculoskeletal 0.991 0.958 – 1.03 0.617 4107 32972 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.936 0.913 – 0.96 3.15e-07 9223 36921 all phecode
743.1 Osteoporosis Musculoskeletal 0.913 0.879 – 0.95 4.71e-06 3712 19477 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.912 0.877 – 0.948 3.46e-06 3657 19276 all phecode
743.12 Senile osteoporosis Musculoskeletal 0.831 0.763 – 0.905 1.99e-05 703 5804 all phecode
743.13 Other specified osteoporosis Musculoskeletal 0.914 0.808 – 1.03 0.151 321 3141 all phecode
743.2 Pathologic fracture Musculoskeletal 0.947 0.886 – 1.01 0.103 1112 10563 all phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 0.986 0.892 – 1.09 0.79 475 4629 all phecode
743.22 Pathologic fracture of femur Musculoskeletal 1.01 0.842 – 1.22 0.9 143 1391 all phecode
743.4 Stress fracture Musculoskeletal 0.948 0.851 – 1.06 0.331 407 4046 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.927 0.902 – 0.954 1.32e-07 6970 35237 all phecode
745 Pain in joint Musculoskeletal 0.991 0.972 – 1.01 0.343 19848 26918 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.985 0.941 – 1.03 0.529 2236 22256 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.02 0.971 – 1.08 0.397 1767 17598 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.952 0.876 – 1.04 0.256 650 6497 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.07 0.992 – 1.16 0.0777 751 7480 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.08 0.974 – 1.2 0.139 410 4090 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.873 0.793 – 0.961 0.00555 501 5010 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.04 0.853 – 1.27 0.698 111 1110 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.894 0.815 – 0.98 0.017 555 5549 all phecode
749.1 Cleft palate Congenital Anomalies 0.763 0.616 – 0.945 0.0134 97 970 all phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.953 0.771 – 1.18 0.657 105 1041 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.972 0.904 – 1.04 0.435 893 8919 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.912 0.816 – 1.02 0.109 366 3655 all phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.957 0.788 – 1.16 0.657 119 1185 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.903 0.725 – 1.12 0.359 99 982 all phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 0.844 0.703 – 1.01 0.0699 134 1332 all phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 1.02 0.772 – 1.36 0.869 60 593 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.993 0.903 – 1.09 0.888 531 5300 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.933 0.825 – 1.05 0.267 313 3129 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.08 0.929 – 1.25 0.322 222 2214 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.02 0.97 – 1.07 0.477 2008 19975 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.985 0.9 – 1.08 0.735 574 5740 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.01 0.902 – 1.13 0.894 384 3840 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.919 0.775 – 1.09 0.332 153 1527 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.04 0.977 – 1.1 0.235 1379 13704 all phecode
751.21 Cystic kidney disease Congenital Anomalies 1.02 0.953 – 1.1 0.545 976 9685 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.01 0.891 – 1.14 0.878 294 2927 all phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.04 0.893 – 1.22 0.588 182 1809 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.11 1.04 – 1.19 0.00107 1133 11313 all phecode
752.1 Neural tube defects Congenital Anomalies 1.13 1.05 – 1.21 0.000781 923 9209 all phecode
752.11 Spina bifida Congenital Anomalies 1.08 0.918 – 1.26 0.365 176 1760 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.04 0.903 – 1.19 0.601 232 2320 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.08 0.93 – 1.26 0.304 207 2051 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.08 0.815 – 1.44 0.577 58 580 all phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 1.08 0.81 – 1.45 0.594 56 546 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.11 1.04 – 1.18 0.00108 1216 12116 all phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 1.07 0.889 – 1.29 0.471 135 1333 all phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 1.08 0.985 – 1.18 0.103 558 5570 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.991 0.916 – 1.07 0.826 747 7458 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.984 0.88 – 1.1 0.773 368 3663 all phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 0.957 0.746 – 1.23 0.729 74 740 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.971 0.86 – 1.1 0.631 321 3205 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.01 0.862 – 1.18 0.897 185 1847 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.963 0.908 – 1.02 0.207 1358 13579 all phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.847 0.653 – 1.1 0.213 68 680 all phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 0.971 0.758 – 1.24 0.818 71 694 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.887 0.789 – 0.997 0.0443 335 3346 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.987 0.923 – 1.06 0.708 1003 10014 all phecode
757 Congenital anomalies of the integument Congenital Anomalies 0.869 0.779 – 0.968 0.0107 401 4001 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.88 0.754 – 1.03 0.107 185 1845 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.904 0.755 – 1.08 0.274 135 1349 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.966 0.882 – 1.06 0.456 557 5566 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.95 0.733 – 1.23 0.698 71 710 all phecode
760 Back pain Symptoms 1.07 1.05 – 1.09 1.09e-10 16037 30719 all phecode
761 Cervicalgia Symptoms 1.02 0.988 – 1.04 0.275 6528 39755 all phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 1.04 1.01 – 1.08 0.024 3657 32599 all phecode
764 Sciatica Symptoms 1.09 1.05 – 1.13 1.32e-05 3542 32015 all phecode
765 Cervical radiculitis Symptoms 1.03 0.977 – 1.08 0.293 1799 17851 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.06 1.03 – 1.09 0.000386 5124 37132 all phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.03 0.85 – 1.24 0.778 117 1168 all phecode
769 Nonallopathic lesions NEC Symptoms 0.985 0.923 – 1.05 0.646 1131 11220 all phecode
770 Myalgia and myositis unspecified Symptoms 1.06 1.03 – 1.09 0.000131 5533 34303 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.06 1.03 – 1.1 0.000117 4799 35575 all phecode
771.1 Swelling of limb Symptoms 1.13 1.1 – 1.17 1.75e-16 5743 35539 all phecode
771.2 Cramp of limb Symptoms 1.04 0.975 – 1.11 0.225 1079 10568 all phecode
772 Symptoms of the muscles Symptoms 0.914 0.871 – 0.959 0.000251 2042 20221 all phecode
772.1 Muscular wasting and disuse atrophy Symptoms 0.984 0.885 – 1.09 0.759 422 4199 all phecode
772.2 Spasm of muscle Symptoms 1.01 0.963 – 1.05 0.756 2299 22726 all phecode
772.3 Muscle weakness Symptoms 1.05 1.01 – 1.09 0.0195 2949 28064 all phecode
772.4 Rhabdomyolysis Symptoms 1.04 0.88 – 1.24 0.625 159 1572 all phecode
772.6 Facial weakness Symptoms 0.997 0.902 – 1.1 0.959 478 4742 all phecode
780 Hypothermia/Chills Symptoms 1.04 0.937 – 1.15 0.482 453 4514 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.03 0.992 – 1.08 0.12 2822 26225 all phecode
781.1 Loss of height Symptoms 0.968 0.797 – 1.18 0.745 130 1269 all phecode
781.2 Abnormal posture Symptoms 0.963 0.728 – 1.27 0.791 57 567 all phecode
782.3 Edema Symptoms 1.18 1.14 – 1.21 3.18e-27 5874 36788 all phecode
782.6 Pallor and flushing Symptoms 0.924 0.86 – 0.993 0.0305 927 9252 all phecode
783 Fever of unknown origin Symptoms 1.07 1.04 – 1.1 2.82e-06 5733 40720 all phecode
783.1 Postprocedural fever Symptoms 1.14 1.01 – 1.29 0.0367 300 2992 all phecode
785 Abdominal pain Symptoms 1.05 1.03 – 1.07 9.92e-06 16458 30297 all phecode
788 Syncope and collapse Symptoms 1.02 0.987 – 1.06 0.213 3851 35832 all phecode
789 Nausea and vomiting Symptoms 1.06 1.03 – 1.08 2.65e-06 10568 36098 all phecode
789.1 Persistent vomiting Symptoms 1.19 1.1 – 1.28 7.37e-06 798 7924 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.08 1.03 – 1.13 0.000794 2363 22690 all phecode
790.1 Elevated sedimentation rate Symptoms 1.18 1.02 – 1.36 0.0258 236 2322 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.07 1.04 – 1.1 2.3e-07 7539 37788 all phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.21 1.07 – 1.36 0.00267 309 3075 all phecode
790.9 Abnormal arterial blood gases Symptoms 1.25 1.05 – 1.49 0.0118 155 1521 all phecode
791 Gangrene Symptoms 1.08 0.959 – 1.22 0.198 313 3115 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 0.981 0.94 – 1.02 0.383 2820 14872 all phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 0.997 0.933 – 1.07 0.931 1100 9861 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.99 0.9 – 1.09 0.843 515 5133 all phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 0.984 0.939 – 1.03 0.489 2182 20242 all phecode
795.8 Abnormal tumor markers Symptoms 0.912 0.866 – 0.96 0.000492 1745 15551 all phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 1.17 0.9 – 1.53 0.239 61 605 all phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 0.917 0.787 – 1.07 0.267 201 2000 all phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.874 0.831 – 0.919 1.37e-07 2125 9930 all phecode
797 Shock Symptoms 1.1 1.01 – 1.21 0.028 605 6050 all phecode
797.1 Cardiogenic shock Symptoms 1.18 1.03 – 1.36 0.0148 242 2420 all phecode
798 Malaise and fatigue Symptoms 1.02 0.994 – 1.04 0.165 11539 35196 all phecode
798.1 Chronic fatigue syndrome Symptoms 1.01 0.957 – 1.06 0.783 1823 17795 all phecode
800 Fracture of lower limb Injuries & Poisonings 0.979 0.937 – 1.02 0.365 2344 22951 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.975 0.885 – 1.08 0.617 512 4961 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.958 0.88 – 1.04 0.311 670 6582 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.02 0.95 – 1.1 0.573 898 8966 all phecode
800.4 Fracture of patella Injuries & Poisonings 0.945 0.842 – 1.06 0.334 346 3456 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.01 0.965 – 1.06 0.693 2358 22645 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.02 0.96 – 1.09 0.46 1120 11178 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.911 0.814 – 1.02 0.103 380 3765 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.92 0.877 – 0.965 0.000615 2051 20360 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.03 0.948 – 1.11 0.518 734 7322 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.891 0.835 – 0.95 0.000457 1112 11075 all phecode
803.21 Colles' fracture Injuries & Poisonings 0.806 0.71 – 0.916 0.000907 291 2904 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.858 0.781 – 0.943 0.00142 514 5140 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.91 0.863 – 0.96 0.00056 1628 16042 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1 0.946 – 1.06 0.911 1336 13242 all phecode
807 Fracture of ribs Injuries & Poisonings 0.982 0.905 – 1.07 0.659 683 6815 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.962 0.924 – 1 0.0541 2941 28633 all phecode
816 Cerebral laceration and contusion Injuries & Poisonings 1.25 0.933 – 1.66 0.137 54 531 all phecode
817 Concussion Injuries & Poisonings 1 0.939 – 1.07 0.898 1018 10149 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.879 0.778 – 0.992 0.036 311 3104 all phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.879 0.705 – 1.1 0.253 90 895 all phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 0.933 0.751 – 1.16 0.531 97 970 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.968 0.926 – 1.01 0.16 2287 22671 all phecode
830 Dislocation Injuries & Poisonings 0.961 0.928 – 0.996 0.0276 3862 34720 all phecode
835 Internal derangement of knee Injuries & Poisonings 0.987 0.942 – 1.03 0.572 2231 21628 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.07 0.972 – 1.18 0.166 496 4954 all phecode
840 Sprains and strains Injuries & Poisonings 0.975 0.95 – 1 0.0554 7838 37998 all phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.998 0.909 – 1.1 0.967 537 5356 all phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 1.01 0.96 – 1.07 0.63 1640 16263 all phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.953 0.915 – 0.993 0.0212 2875 24879 all phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.98 0.928 – 1.04 0.469 1583 15592 all phecode
842 Other sprains and strains Injuries & Poisonings 0.978 0.923 – 1.04 0.44 1407 13924 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.08 1.03 – 1.13 0.00175 2072 20649 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.15 1.11 – 1.2 2.14e-12 2982 27545 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.06 0.962 – 1.17 0.234 460 4600 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.14 1.09 – 1.19 1.28e-07 1985 19675 all phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.05 0.916 – 1.19 0.512 264 2640 all phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.08 0.954 – 1.23 0.22 293 2929 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.11 1.04 – 1.18 0.000698 1310 13087 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.06 1.01 – 1.11 0.0151 2213 21944 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.08 1.03 – 1.13 0.00192 2110 21070 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1.07 0.907 – 1.26 0.425 166 1660 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.03 1 – 1.07 0.0473 4117 36734 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.03 0.885 – 1.2 0.705 204 2026 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.891 0.75 – 1.06 0.192 144 1437 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.878 0.828 – 0.931 1.51e-05 1346 13301 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.927 0.8 – 1.07 0.313 207 2057 all phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 0.879 0.77 – 1 0.0554 275 2724 all phecode
870.6 Open wound of neck Injuries & Poisonings 0.995 0.86 – 1.15 0.95 214 2128 all phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.18 0.992 – 1.41 0.0621 144 1440 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.03 0.997 – 1.07 0.075 3530 32903 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.997 0.911 – 1.09 0.95 572 5701 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.944 0.88 – 1.01 0.102 984 9772 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.28 1.16 – 1.41 7.58e-07 490 4843 all phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.13 0.993 – 1.28 0.0635 295 2921 all phecode
872 Traumatic amputation Injuries & Poisonings 1.18 1.07 – 1.29 0.000554 551 5477 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.2 1.02 – 1.42 0.025 170 1697 all phecode
875 Non-healing surgical wound Injuries & Poisonings 1.2 1.1 – 1.31 6.17e-05 572 5720 all phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.25 1.16 – 1.35 1.59e-08 802 8003 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.02 0.949 – 1.09 0.654 1010 10096 all phecode
910 Superficial injury, infected Injuries & Poisonings 0.884 0.725 – 1.08 0.227 119 1161 all phecode
911 Blister Injuries & Poisonings 1.21 1.07 – 1.37 0.00295 302 2996 all phecode
912 Insect bite Injuries & Poisonings 0.979 0.887 – 1.08 0.666 492 4886 all phecode
913 Toxic effect of venom Injuries & Poisonings 0.805 0.714 – 0.907 0.000356 337 3326 all phecode
916 Contusion Injuries & Poisonings 1.03 0.999 – 1.07 0.0601 4296 38033 all phecode
930 Allergic reaction to food Injuries & Poisonings 1 0.926 – 1.08 0.982 763 7596 all phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.916 0.844 – 0.994 0.0348 714 7072 all phecode
938 Dermatitis due to solar radiation Dermatologic 0.901 0.873 – 0.929 2.78e-11 5567 29098 all phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.963 0.832 – 1.12 0.614 217 2164 all phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.894 0.866 – 0.923 3.06e-12 5307 28656 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.987 0.959 – 1.01 0.347 6704 32389 all phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 0.983 0.78 – 1.24 0.884 91 870 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.11 0.946 – 1.3 0.202 188 1880 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.07 0.939 – 1.23 0.298 269 2688 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.947 0.86 – 1.04 0.27 500 4940 all phecode
947 Urticaria Dermatologic 0.989 0.927 – 1.05 0.724 1177 11454 all phecode
949 Allergies, other Injuries & Poisonings 1.02 0.992 – 1.05 0.157 7251 32350 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.07 0.973 – 1.18 0.162 494 4940 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.922 0.769 – 1.1 0.378 136 1352 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.07 1 – 1.14 0.0367 1217 12158 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.04 0.877 – 1.22 0.681 169 1688 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.997 0.818 – 1.22 0.978 114 1140 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.14 1.09 – 1.19 7.88e-09 2479 22087 all phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 1.16 1.03 – 1.31 0.0129 342 3403 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.14 1.08 – 1.21 9.94e-07 1636 16005 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.12 1.02 – 1.23 0.0142 528 5234 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.13 1.06 – 1.21 0.00021 1065 10347 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.1 1.02 – 1.19 0.0158 803 7976 all phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.13 1.01 – 1.27 0.0306 379 3782 all phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 1.25 0.954 – 1.65 0.104 62 612 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.1 0.995 – 1.21 0.0631 478 4773 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.03 0.983 – 1.07 0.239 2533 24531 all phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.03 0.988 – 1.08 0.152 2469 24057 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.11 1.02 – 1.2 0.0135 743 7337 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.12 1.03 – 1.21 0.00857 712 7027 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.05 0.976 – 1.13 0.188 864 8601 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.17 1.1 – 1.23 1.05e-07 1469 14402 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.946 0.777 – 1.15 0.579 119 1182 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.933 0.756 – 1.15 0.522 103 1006 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1 0.94 – 1.06 1 1254 12464 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.15 1.01 – 1.31 0.0353 281 2797 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.2 0.926 – 1.56 0.168 67 643 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.2 1.06 – 1.36 0.00518 288 2858 all phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 1.23 0.971 – 1.55 0.086 80 776 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.22 0.998 – 1.49 0.0522 104 1034 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.09 0.892 – 1.33 0.395 113 1130 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.1 0.874 – 1.39 0.41 81 810 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.18 0.914 – 1.53 0.201 71 703 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.12 1.06 – 1.18 3.74e-05 1763 16599 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.04 0.998 – 1.07 0.0655 3448 30885 all phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 1 0.945 – 1.06 0.971 1391 13877 all phecode
985 Toxic effect of other metals Injuries & Poisonings 1.19 0.9 – 1.58 0.221 57 564 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.975 0.807 – 1.18 0.788 129 1275 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.03 0.991 – 1.06 0.143 3927 31223 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.14 1.09 – 1.2 1.12e-08 2192 21710 all phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.15 1.01 – 1.31 0.0309 291 2910 all phecode
994.2 Sepsis Injuries & Poisonings 1.14 1.09 – 1.2 4.13e-08 2086 20666 all phecode
994.21 Septic shock Injuries & Poisonings 1.19 1.09 – 1.3 9.49e-05 627 6260 all phecode
008 Intestinal infection Infectious Diseases 1.01 0.937 – 1.1 0.722 745 6950 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.19 1.05 – 1.34 0.00633 321 2987 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.19 1.03 – 1.36 0.0163 251 2331 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.08 0.919 – 1.28 0.343 168 1792 exclusion phecode
010 Tuberculosis Infectious Diseases 0.99 0.76 – 1.29 0.941 61 539 exclusion phecode
031 Diseases due to other mycobacteria Infectious Diseases 1.02 0.682 – 1.52 0.931 27 197 exclusion phecode
038 Septicemia Infectious Diseases 1.26 1.14 – 1.38 1.72e-06 551 5136 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.21 0.989 – 1.48 0.0642 115 1172 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.19 0.873 – 1.61 0.275 50 455 exclusion phecode
038.3 Bacteremia Infectious Diseases 1.23 1.08 – 1.41 0.0019 266 2396 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.13 1.06 – 1.2 8.6e-05 1319 9006 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.26 1.13 – 1.41 6.26e-05 349 3617 exclusion phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.28 1.1 – 1.5 0.00198 181 1916 exclusion phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.28 1.08 – 1.51 0.00357 157 1700 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.23 1.1 – 1.37 0.000362 381 3462 exclusion phecode
041.21 Rheumatic fever / chorea Infectious Diseases 0.964 0.708 – 1.31 0.815 50 554 exclusion phecode
041.4 E. coli Infectious Diseases 1.21 1.05 – 1.38 0.00794 260 2614 exclusion phecode
041.8 H. pylori Infectious Diseases 0.931 0.711 – 1.22 0.606 58 595 exclusion phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.37 1.08 – 1.73 0.00949 96 849 exclusion phecode
053 Herpes zoster Infectious Diseases 0.936 0.835 – 1.05 0.254 369 3324 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.04 0.761 – 1.42 0.812 50 459 exclusion phecode
054 Herpes simplex Infectious Diseases 0.986 0.886 – 1.1 0.795 422 3794 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.1 0.939 – 1.29 0.235 193 1614 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 2.02 1.04 – 3.95 0.0392 11 160 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 1.01 0.747 – 1.37 0.943 52 441 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.22 1.01 – 1.48 0.0415 129 966 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.23 0.896 – 1.7 0.198 53 395 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.22 1.06 – 1.4 0.00565 245 2187 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.51 1.12 – 2.02 0.00597 59 289 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.56 1.13 – 2.16 0.00663 50 218 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.909 0.845 – 0.977 0.00991 911 7141 exclusion phecode
079 Viral infection Infectious Diseases 1 0.948 – 1.06 0.951 1707 8160 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.893 0.831 – 0.959 0.00179 975 7161 exclusion phecode
079.2 Infectious mononucleosis Infectious Diseases 0.858 0.694 – 1.06 0.154 106 885 exclusion phecode
079.9 Viremia, NOS Infectious Diseases 1.3 1.12 – 1.51 0.000491 214 2028 exclusion phecode
080 Postoperative infection Infectious Diseases 1.21 1.1 – 1.33 5.12e-05 540 5845 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.23 1.11 – 1.38 0.000178 389 3473 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.04 0.909 – 1.18 0.598 277 2444 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.999 0.917 – 1.09 0.974 644 6718 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.997 0.911 – 1.09 0.955 555 6022 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.01 0.902 – 1.14 0.808 340 3534 exclusion phecode
110.12 Althete's foot Infectious Diseases 0.984 0.817 – 1.19 0.869 129 1645 exclusion phecode
110.13 Dermatophytosis of the body Infectious Diseases 0.904 0.753 – 1.08 0.276 131 1711 exclusion phecode
110.2 Dermatomycoses Infectious Diseases 1.08 0.871 – 1.33 0.489 103 952 exclusion phecode
112 Candidiasis Infectious Diseases 1.17 1.09 – 1.26 2.92e-05 876 7564 exclusion phecode
112.3 Candidiasis of skin and nails Infectious Diseases 0.98 0.747 – 1.29 0.885 57 1616 exclusion phecode
117 Mycoses Infectious Diseases 1.07 0.901 – 1.26 0.458 164 1439 exclusion phecode
117.1 Histoplasmosis Infectious Diseases 1.08 0.702 – 1.65 0.738 23 193 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.3 0.956 – 1.77 0.0945 49 340 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.877 0.646 – 1.19 0.4 48 434 exclusion phecode
130.1 Lyme disease Infectious Diseases 0.842 0.6 – 1.18 0.32 38 309 exclusion phecode
131 Protozoan infection Infectious Diseases 1.53 0.839 – 2.78 0.166 11 163 exclusion phecode
132 Infestation (lice, mites) Infectious Diseases 1.25 0.926 – 1.69 0.144 46 468 exclusion phecode
134 Helminthiases Infectious Diseases 1.27 0.811 – 2 0.293 22 177 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.41 0.798 – 2.5 0.236 16 108 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.15 1.07 – 1.24 0.000222 854 7457 exclusion phecode
145 Cancer of mouth Neoplasms 1.31 1.17 – 1.47 1.65e-06 402 2723 exclusion phecode
145.1 Cancer of lip Neoplasms 1.59 0.914 – 2.77 0.101 16 137 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.35 1.14 – 1.59 0.000476 186 1121 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.963 0.759 – 1.22 0.76 79 717 exclusion phecode
145.4 Cancer of the gums Neoplasms 1.6 1.18 – 2.19 0.00291 54 343 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.71 1.3 – 2.25 0.000124 75 363 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.34 1.19 – 1.51 1.26e-06 355 2312 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.59 1.26 – 2.01 0.000106 105 568 exclusion phecode
149.2 Cancer of nasopharynx Neoplasms 1.48 0.979 – 2.25 0.0631 33 211 exclusion phecode
149.3 Cancer of hypopharynx Neoplasms 1.51 0.992 – 2.3 0.0543 28 154 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.38 1.1 – 1.72 0.00483 102 636 exclusion phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 1.44 1.19 – 1.73 0.000121 148 971 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.24 0.918 – 1.67 0.162 60 466 exclusion phecode
150 Cancer of esophagus Neoplasms 1.59 1.29 – 1.97 1.63e-05 99 751 exclusion phecode
151 Cancer of stomach Neoplasms 1.08 0.879 – 1.34 0.449 112 884 exclusion phecode
153 Colorectal cancer Neoplasms 1.03 0.912 – 1.17 0.622 307 2977 exclusion phecode
153.2 Colon cancer Neoplasms 1.02 0.885 – 1.18 0.761 224 2327 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.01 0.861 – 1.18 0.929 194 1749 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.2 0.969 – 1.48 0.0944 109 958 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.14 0.884 – 1.48 0.309 72 634 exclusion phecode
157 Pancreatic cancer Neoplasms 1.25 1.02 – 1.53 0.0337 119 943 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.02 0.914 – 1.15 0.674 366 3192 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.14 1.02 – 1.27 0.0205 398 3485 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.93 0.665 – 1.3 0.673 44 428 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.08 0.782 – 1.49 0.64 44 300 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.23 0.951 – 1.59 0.114 74 624 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 1.01 0.697 – 1.47 0.953 36 255 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.2 1.07 – 1.36 0.00292 327 2562 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.13 0.989 – 1.3 0.0724 254 2026 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 1.11 1 – 1.23 0.0492 438 3720 exclusion phecode
170.1 Bone cancer Neoplasms 1.23 1.06 – 1.43 0.00546 205 1645 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1.06 0.936 – 1.2 0.355 295 2650 exclusion phecode
172 Skin cancer Neoplasms 0.967 0.916 – 1.02 0.223 2005 7136 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.917 0.858 – 0.981 0.0114 1183 6208 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.894 0.82 – 0.975 0.0116 622 5040 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.967 0.912 – 1.03 0.262 1698 6245 exclusion phecode
172.21 Basal cell carcinoma Neoplasms 0.906 0.84 – 0.978 0.0113 900 4642 exclusion phecode
172.22 Squamous cell carcinoma Neoplasms 1.05 0.953 – 1.15 0.347 583 3196 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.841 0.748 – 0.946 0.00404 363 2293 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.919 0.831 – 1.02 0.0991 472 3913 exclusion phecode
174 Breast cancer Neoplasms 0.926 0.858 – 0.998 0.0453 942 4018 exclusion phecode
174.1 Breast cancer [female] Neoplasms 0.926 0.857 – 1 0.0529 905 3840 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.936 0.866 – 1.01 0.0974 886 3818 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.669 0.508 – 0.88 0.00404 65 592 exclusion phecode
175 Acquired absence of breast Neoplasms 0.912 0.803 – 1.04 0.156 301 2272 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.03 0.929 – 1.14 0.575 442 3333 exclusion phecode
180.1 Cervical cancer Neoplasms 1.12 0.928 – 1.34 0.244 135 1295 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.987 0.878 – 1.11 0.82 356 2584 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.958 0.783 – 1.17 0.677 105 1877 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.03 0.911 – 1.17 0.637 313 2979 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.923 0.774 – 1.1 0.378 151 1504 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.916 0.751 – 1.12 0.384 120 1139 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.1 0.922 – 1.32 0.284 150 1531 exclusion phecode
185 Cancer of prostate Neoplasms 0.842 0.744 – 0.954 0.00677 399 1589 exclusion phecode
187 Cancer of other male genital organs Neoplasms 0.883 0.678 – 1.15 0.359 66 631 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.09 0.657 – 1.8 0.746 14 181 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.786 0.577 – 1.07 0.125 42 389 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.16 0.618 – 2.17 0.646 12 97 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.01 0.914 – 1.11 0.857 474 4570 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.03 0.889 – 1.19 0.699 217 2783 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.05 0.892 – 1.23 0.569 179 2436 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.35 0.961 – 1.89 0.0838 43 421 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.02 0.9 – 1.15 0.765 307 2791 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.06 0.93 – 1.2 0.39 290 2565 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.25 1.03 – 1.53 0.0246 116 1178 exclusion phecode
190 Cancer of eye Neoplasms 0.866 0.612 – 1.23 0.418 44 274 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.01 0.881 – 1.15 0.924 257 2389 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.974 0.835 – 1.14 0.738 189 1564 exclusion phecode
191.11 Cancer of brain Neoplasms 1.01 0.858 – 1.19 0.903 166 1311 exclusion phecode
193 Thyroid cancer Neoplasms 1.08 0.926 – 1.27 0.317 180 2295 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.09 0.887 – 1.33 0.427 115 1361 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.02 0.976 – 1.07 0.353 3803 6337 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.02 0.971 – 1.07 0.47 3739 6336 exclusion phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1.34 1.17 – 1.53 1.91e-05 276 1686 exclusion phecode
196 Radiotherapy Neoplasms 1.03 0.937 – 1.13 0.545 560 3437 exclusion phecode
197 Chemotherapy Neoplasms 1.12 1.05 – 1.2 0.000604 1227 5333 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.11 1.04 – 1.19 0.00176 1285 5236 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.1 1.02 – 1.19 0.0184 840 4617 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.27 1.09 – 1.47 0.00182 218 1968 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.08 0.931 – 1.25 0.316 220 1681 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.14 0.968 – 1.33 0.12 193 1429 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.2 1.01 – 1.43 0.0388 154 1229 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.31 1.11 – 1.53 0.000956 188 1540 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.11 0.865 – 1.42 0.419 81 608 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.04 0.977 – 1.12 0.202 1222 6068 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.57 1.06 – 2.31 0.024 30 219 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.26 1.1 – 1.44 0.00086 259 2376 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.37 0.987 – 1.91 0.0601 43 384 exclusion phecode
201 Hodgkin's disease Neoplasms 1.49 1.11 – 2 0.00786 47 409 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.19 1.07 – 1.34 0.00188 375 3286 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.21 1.07 – 1.37 0.00182 318 2810 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.19 1.01 – 1.39 0.0344 183 1510 exclusion phecode
202.22 Reticulosarcoma Neoplasms 1.08 0.756 – 1.55 0.665 36 352 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.03 0.718 – 1.47 0.878 38 319 exclusion phecode
204 Leukemia Neoplasms 1.11 0.937 – 1.32 0.223 153 1343 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1.18 0.874 – 1.6 0.277 58 448 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.22 0.747 – 1.99 0.429 21 173 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.06 0.735 – 1.52 0.762 38 313 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.22 0.93 – 1.6 0.152 62 505 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 1.13 0.778 – 1.64 0.519 36 268 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.22 0.687 – 2.15 0.501 16 128 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.12 0.821 – 1.54 0.463 42 438 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1.01 0.963 – 1.07 0.615 2119 8346 exclusion phecode
209 Neuroendocrine tumors Neoplasms 0.946 0.675 – 1.33 0.749 41 515 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.04 0.942 – 1.15 0.448 499 4205 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.09 1.03 – 1.16 0.00184 1559 8697 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.16 1.05 – 1.29 0.00478 437 3952 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.01 0.904 – 1.12 0.922 415 3699 exclusion phecode
214 Lipoma Neoplasms 1.02 0.894 – 1.17 0.752 260 3192 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.95 0.8 – 1.13 0.554 160 2008 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.975 0.911 – 1.04 0.461 1012 9144 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.92 0.879 – 0.963 0.00037 2817 8094 exclusion phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 1.16 0.841 – 1.61 0.359 45 416 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.838 0.76 – 0.925 0.000421 502 3752 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.842 0.76 – 0.932 0.00094 464 3438 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.927 0.865 – 0.993 0.0309 1154 4797 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.853 0.769 – 0.945 0.00245 461 4411 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.928 0.861 – 1 0.0503 944 4715 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.925 0.801 – 1.07 0.294 226 2392 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.956 0.868 – 1.05 0.372 506 4088 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.764 0.65 – 0.897 0.00106 182 1720 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.04 0.922 – 1.18 0.516 326 2723 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.846 0.711 – 1.01 0.0587 161 1399 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.846 0.702 – 1.02 0.0805 134 1127 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.08 0.949 – 1.23 0.248 275 2764 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.988 0.854 – 1.14 0.875 213 2174 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.32 1.03 – 1.7 0.0314 71 639 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.06 0.925 – 1.2 0.423 259 3226 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.993 0.875 – 1.13 0.914 283 3878 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.06 0.81 – 1.37 0.69 63 965 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.978 0.824 – 1.16 0.8 157 1863 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.879 0.678 – 1.14 0.326 63 1012 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.775 0.704 – 0.853 1.78e-07 538 4535 exclusion phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.73 0.648 – 0.822 2.24e-07 355 2832 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.985 0.932 – 1.04 0.593 1669 8554 exclusion phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.983 0.923 – 1.05 0.599 1210 7778 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.05 0.91 – 1.21 0.499 219 2530 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.02 0.931 – 1.11 0.7 605 5567 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.981 0.888 – 1.08 0.713 475 4945 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.06 0.923 – 1.22 0.403 236 3181 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.06 0.937 – 1.2 0.346 299 3335 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.914 0.748 – 1.12 0.379 118 1249 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.35 0.839 – 2.18 0.215 19 307 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.88 0.685 – 1.13 0.314 72 698 exclusion phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.903 0.633 – 1.29 0.573 38 356 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.03 0.977 – 1.1 0.244 1647 7677 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.01 0.903 – 1.13 0.847 351 4262 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.14 1.01 – 1.3 0.0384 284 3037 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.03 0.973 – 1.1 0.294 1538 7562 exclusion phecode
245 Thyroiditis Endocrine/metabolic 1.23 1.04 – 1.44 0.0137 178 2110 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.26 1.05 – 1.51 0.0134 138 1770 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.25 1.04 – 1.5 0.0153 137 1751 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.03 0.968 – 1.1 0.33 1301 7120 exclusion phecode
246.2 Thyroid cyst Endocrine/metabolic 0.875 0.57 – 1.34 0.542 25 228 exclusion phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1.04 0.896 – 1.2 0.625 218 2156 exclusion phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.25 1.03 – 1.52 0.0223 169 1894 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.09 1.03 – 1.16 0.00348 1798 8752 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.2 1.03 – 1.39 0.0185 469 2920 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.81 1.26 – 2.61 0.00138 103 226 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.25 0.982 – 1.59 0.0693 154 616 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.37 1.06 – 1.76 0.0149 189 705 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.49 1.16 – 1.91 0.00197 160 588 exclusion phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 1.37 0.939 – 2.01 0.101 49 173 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.14 1.06 – 1.24 0.000672 1078 7827 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.82 1.23 – 2.69 0.00274 77 288 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.47 1.22 – 1.77 4.62e-05 173 3130 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.2 0.988 – 1.46 0.0664 207 2284 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.25 1.05 – 1.5 0.0139 215 3893 exclusion phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.26 0.974 – 1.64 0.0781 71 1331 exclusion phecode
250.3 Insulin pump user Endocrine/metabolic 1.25 1.09 – 1.43 0.00138 438 5081 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.07 1 – 1.15 0.0477 1238 8248 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.965 0.831 – 1.12 0.638 232 4125 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.09 1.01 – 1.17 0.0272 1125 7996 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.85 1.1 – 3.12 0.0209 26 290 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.26 1.04 – 1.53 0.0172 205 3102 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.11 0.959 – 1.29 0.16 256 2093 exclusion phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.1 0.96 – 1.27 0.168 245 1974 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.14 0.988 – 1.32 0.0728 310 2348 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.05 0.952 – 1.16 0.325 477 5165 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.04 0.935 – 1.15 0.493 435 4715 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.16 0.934 – 1.44 0.18 98 1179 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1 0.848 – 1.18 0.989 164 1895 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.07 0.793 – 1.45 0.65 48 670 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.849 0.508 – 1.42 0.534 11 203 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.857 0.609 – 1.21 0.376 32 477 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.23 0.746 – 2.03 0.416 15 182 exclusion phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 0.772 0.47 – 1.27 0.307 18 220 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.22 0.806 – 1.86 0.343 30 242 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.07 0.944 – 1.22 0.284 276 3379 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.881 0.667 – 1.16 0.369 56 924 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.713 0.475 – 1.07 0.102 26 495 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.21 0.73 – 2.02 0.455 15 281 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.11 0.925 – 1.34 0.255 131 1432 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.15 0.946 – 1.39 0.165 123 1361 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.952 0.828 – 1.09 0.492 237 3240 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.808 0.636 – 1.03 0.0799 78 2257 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1.03 0.857 – 1.24 0.758 127 1530 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.03 0.855 – 1.24 0.755 122 1469 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.56 0.943 – 2.6 0.0834 17 186 exclusion phecode
258.1 Postablative ovarian failure Endocrine/metabolic 1 0.685 – 1.47 0.989 31 330 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 1.02 0.877 – 1.19 0.803 201 2439 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.29 1.2 – 1.39 3.23e-12 988 5553 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.48 1.21 – 1.83 0.000201 147 559 exclusion phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.45 1.32 – 1.59 6.82e-15 600 3325 exclusion phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.45 1.24 – 1.7 4.39e-06 214 1201 exclusion phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.5 1.28 – 1.76 7.32e-07 210 1199 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.35 1.18 – 1.55 1.28e-05 264 1878 exclusion phecode
260.7 Polyphagia Endocrine/metabolic 0.884 0.522 – 1.5 0.645 16 167 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.14 1.08 – 1.21 6.94e-06 1599 8182 exclusion phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1.67 1.03 – 2.7 0.0385 22 160 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.31 1.11 – 1.55 0.00143 175 1833 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.14 1.08 – 1.21 9.8e-06 1500 8199 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.856 0.511 – 1.43 0.555 14 118 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.16 1.02 – 1.33 0.0293 269 2874 exclusion phecode
263 Other nutritional deficiency Endocrine/metabolic 1.24 1.11 – 1.39 0.000155 368 3637 exclusion phecode
264 Lack of normal physiological development Endocrine/metabolic 1.15 0.924 – 1.44 0.209 103 699 exclusion phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.2 0.878 – 1.63 0.254 51 309 exclusion phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 1 0.703 – 1.43 0.993 38 286 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.37 1.2 – 1.56 1.74e-06 286 3036 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.18 1.01 – 1.37 0.0353 201 2098 exclusion phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.89 0.61 – 1.3 0.544 34 418 exclusion phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.816 0.543 – 1.22 0.326 29 348 exclusion phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 1.14 0.64 – 2.05 0.649 10 223 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.26 1.07 – 1.5 0.00698 164 1518 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.24 0.954 – 1.61 0.108 72 737 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 0.727 0.436 – 1.21 0.222 19 142 exclusion phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 0.85 0.473 – 1.53 0.586 18 134 exclusion phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.43 1.1 – 1.85 0.00672 76 663 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1 0.901 – 1.11 1 417 6296 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.983 0.883 – 1.09 0.759 394 6130 exclusion phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.35 0.884 – 2.06 0.165 26 230 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.04 0.986 – 1.09 0.158 2862 7532 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.04 0.986 – 1.09 0.165 2851 7518 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.04 0.962 – 1.12 0.323 885 5677 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.07 0.883 – 1.3 0.481 112 2933 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.03 0.924 – 1.15 0.599 426 4669 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.979 0.747 – 1.28 0.875 61 737 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.14 1 – 1.3 0.0491 266 4357 exclusion phecode
274.1 Gout Endocrine/metabolic 1.15 1.01 – 1.33 0.0408 232 4169 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.22 0.994 – 1.49 0.0578 106 2021 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.978 0.702 – 1.36 0.895 44 379 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.02 0.734 – 1.42 0.907 43 358 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.23 1.15 – 1.32 8.41e-09 945 8233 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.968 0.647 – 1.45 0.873 27 469 exclusion phecode
275.11 Hereditary hemochromatosis Hematopoietic 1.1 0.5 – 2.44 0.806 7 203 exclusion phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 1.07 0.612 – 1.88 0.807 15 153 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.48 1.29 – 1.69 1.02e-08 273 2426 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.2 1.11 – 1.3 3.96e-06 738 7005 exclusion phecode
275.51 Hypocalcemia Endocrine/metabolic 1.29 1.11 – 1.49 0.000618 218 1971 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.28 1.13 – 1.45 0.000112 320 2783 exclusion phecode
275.6 Hypercalcemia Endocrine/metabolic 1.22 1.07 – 1.38 0.00223 290 3120 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.25 1.19 – 1.32 1.2e-17 2041 8801 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.32 1.24 – 1.4 1.86e-18 1364 7723 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.28 1.05 – 1.56 0.0146 127 1035 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.34 1.22 – 1.46 1.93e-10 637 4587 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.37 1.25 – 1.49 9.08e-12 600 5079 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.35 1.22 – 1.5 1.28e-08 444 4590 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.3 1.17 – 1.45 5.69e-07 443 4136 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.32 1.18 – 1.48 1.94e-06 371 3556 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.4 1.14 – 1.72 0.00117 124 982 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.28 1.2 – 1.36 3.93e-13 1141 7954 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.51 1.3 – 1.74 2.5e-08 239 2587 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 0.956 0.63 – 1.45 0.834 24 289 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.14 1.05 – 1.24 0.0013 701 8379 exclusion phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.44 0.99 – 2.08 0.0566 28 771 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.05 0.889 – 1.25 0.553 161 1518 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.969 0.811 – 1.16 0.734 143 2051 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.991 0.809 – 1.21 0.931 109 1709 exclusion phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.81 1.16 – 2.83 0.00926 17 1926 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.29 1.19 – 1.4 1.4e-09 678 10325 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.6 1.37 – 1.87 1.91e-09 177 10321 exclusion phecode
278.11 Morbid obesity Endocrine/metabolic 1.78 1.31 – 2.41 0.00021 40 10260 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 0.981 0.69 – 1.39 0.916 31 1298 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.2 1.06 – 1.36 0.00315 307 7284 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.13 1.05 – 1.22 0.00179 806 6578 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.19 1.05 – 1.34 0.00533 328 2565 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.15 0.914 – 1.45 0.23 93 720 exclusion phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 1.02 0.874 – 1.19 0.814 198 1809 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1 0.937 – 1.07 0.985 1119 8305 exclusion phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 1.08 0.916 – 1.28 0.347 171 1473 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.16 1.09 – 1.25 1.44e-05 1078 7054 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.16 1.09 – 1.25 1.52e-05 1043 7020 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.21 1.08 – 1.34 0.000544 408 3775 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.24 1.01 – 1.53 0.0386 116 1161 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.13 0.856 – 1.49 0.392 62 579 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.34 0.876 – 2.04 0.178 28 267 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.99 0.703 – 1.4 0.956 43 434 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.32 1.01 – 1.74 0.0445 63 652 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.01 0.781 – 1.31 0.939 69 693 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 0.972 0.698 – 1.35 0.864 46 437 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.28 0.908 – 1.8 0.16 38 411 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.07 0.752 – 1.53 0.695 33 345 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.888 0.531 – 1.49 0.652 15 152 exclusion phecode
284 Aplastic anemia Hematopoietic 1.32 1.12 – 1.55 0.000697 181 1365 exclusion phecode
284.1 Pancytopenia Hematopoietic 1.31 1.1 – 1.56 0.00218 157 1208 exclusion phecode
285 Other anemias Hematopoietic 1.17 1.11 – 1.22 6.57e-11 2829 7835 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.21 1.12 – 1.31 1.33e-06 806 5912 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.39 1.27 – 1.53 1.14e-11 523 4091 exclusion phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.5 1.3 – 1.73 3.6e-08 221 1743 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.32 1.11 – 1.55 0.00124 182 1437 exclusion phecode
286 Coagulation defects Hematopoietic 1.13 1.04 – 1.22 0.00299 767 7586 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.781 0.573 – 1.06 0.117 50 594 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.628 0.376 – 1.05 0.0768 20 197 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.979 0.626 – 1.53 0.927 22 307 exclusion phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.06 0.963 – 1.16 0.248 550 5391 exclusion phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 1.09 0.749 – 1.6 0.643 34 325 exclusion phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 1.14 0.837 – 1.55 0.409 50 500 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.954 0.64 – 1.42 0.815 24 279 exclusion phecode
286.6 Defibrination syndrome Hematopoietic 1.05 0.955 – 1.16 0.299 491 5592 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.09 0.994 – 1.19 0.0691 588 6545 exclusion phecode
286.8 Hypercoagulable state Hematopoietic 1.05 0.884 – 1.25 0.568 158 1963 exclusion phecode
286.81 Primary hypercoagulable state Hematopoietic 1.01 0.84 – 1.2 0.956 150 1863 exclusion phecode
286.9 Abnormal coagulation profile Hematopoietic 1.27 1.1 – 1.47 0.00121 224 2405 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.1 1.01 – 1.19 0.0207 740 6201 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.867 0.656 – 1.15 0.319 55 491 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.12 1.03 – 1.21 0.00834 671 5659 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.04 0.854 – 1.26 0.723 119 1303 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.23 1.02 – 1.49 0.0329 135 1209 exclusion phecode
287.4 Qualitative platelet defects Hematopoietic 1.08 0.69 – 1.68 0.74 23 267 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.15 1.08 – 1.23 1.46e-05 1201 8361 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.15 1.04 – 1.26 0.00581 515 3506 exclusion phecode
288.11 Neutropenia Hematopoietic 1.27 1.13 – 1.43 9e-05 341 2383 exclusion phecode
288.2 Elevated white blood cell count Hematopoietic 1.13 1.05 – 1.21 0.000615 962 7794 exclusion phecode
288.3 Eosinophilia Hematopoietic 0.96 0.692 – 1.33 0.807 46 411 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.13 1.02 – 1.26 0.0183 440 3991 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.06 0.922 – 1.23 0.394 232 2168 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.09 1.02 – 1.17 0.0163 946 7908 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1.31 1.04 – 1.67 0.0241 79 834 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.53 1.08 – 2.17 0.0176 40 463 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.46 1.17 – 1.82 0.000713 99 843 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.1 0.969 – 1.24 0.146 326 2192 exclusion phecode
290.1 Dementias Mental Disorders 0.931 0.763 – 1.14 0.484 116 945 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.975 0.658 – 1.45 0.901 32 269 exclusion phecode
290.12 Dementia with cerebral degenerations Mental Disorders 0.694 0.424 – 1.14 0.146 15 151 exclusion phecode
290.13 Senile dementia Mental Disorders 0.936 0.729 – 1.2 0.604 75 604 exclusion phecode
290.16 Vascular dementia Mental Disorders 0.968 0.582 – 1.61 0.9 20 144 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.12 0.957 – 1.31 0.16 200 1357 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.01 0.877 – 1.17 0.843 208 1877 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.14 1.04 – 1.25 0.00409 540 5706 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.943 0.668 – 1.33 0.74 36 500 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.07 0.893 – 1.28 0.466 135 1160 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.18 1.06 – 1.31 0.00286 404 4403 exclusion phecode
292 Neurological disorders Mental Disorders 1.11 1.04 – 1.18 0.000791 1340 8914 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.12 1.02 – 1.24 0.0172 514 4104 exclusion phecode
292.11 Aphasia Mental Disorders 0.991 0.833 – 1.18 0.916 158 1414 exclusion phecode
292.12 Symbolic dysfunction Mental Disorders 0.85 0.625 – 1.15 0.298 45 448 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.926 0.739 – 1.16 0.503 83 779 exclusion phecode
292.3 Memory loss Mental Disorders 0.926 0.831 – 1.03 0.161 394 3874 exclusion phecode
292.4 Altered mental status Mental Disorders 1.22 1.11 – 1.34 2.97e-05 544 4644 exclusion phecode
292.5 Transient alteration of awareness Mental Disorders 1.08 0.874 – 1.33 0.48 105 944 exclusion phecode
292.6 Hallucinations Mental Disorders 1.37 1 – 1.89 0.0491 50 472 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.25 1.01 – 1.55 0.0366 109 942 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.08 1.01 – 1.16 0.0183 1033 8730 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.18 1.02 – 1.37 0.0274 211 1890 exclusion phecode
295.1 Schizophrenia Mental Disorders 0.961 0.667 – 1.38 0.831 30 327 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.28 0.838 – 1.96 0.252 24 252 exclusion phecode
295.3 Psychosis Mental Disorders 1.24 1.05 – 1.46 0.0104 175 1527 exclusion phecode
296 Mood disorders Mental Disorders 1.1 1.05 – 1.15 5.69e-05 3358 5135 exclusion phecode
296.1 Bipolar Mental Disorders 1.24 1.09 – 1.41 0.00124 288 3055 exclusion phecode
296.2 Depression Mental Disorders 1.09 1.04 – 1.15 0.000229 3217 5134 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.11 1.05 – 1.16 4.65e-05 2978 5134 exclusion phecode
297 Suicidal ideation or attempt Mental Disorders 1.2 1.05 – 1.37 0.00612 273 2462 exclusion phecode
297.1 Suicidal ideation Mental Disorders 1.16 1 – 1.35 0.0467 211 2001 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.28 1.03 – 1.59 0.0244 99 768 exclusion phecode
300 Anxiety disorders Mental Disorders 1.11 1.06 – 1.16 2.99e-06 3742 5135 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.12 1.07 – 1.17 8.63e-07 3556 5135 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 1.11 1.04 – 1.18 0.00231 1339 4978 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.08 0.952 – 1.22 0.231 330 3115 exclusion phecode
300.13 Phobia Mental Disorders 1.14 0.991 – 1.32 0.0667 243 2450 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.719 0.558 – 0.927 0.011 75 881 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.13 1.03 – 1.24 0.00785 590 4164 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.17 0.934 – 1.46 0.175 103 1260 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.11 0.949 – 1.3 0.192 192 2136 exclusion phecode
301 Personality disorders Mental Disorders 1.18 0.962 – 1.44 0.114 110 1340 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.17 0.895 – 1.52 0.255 64 700 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 0.923 0.838 – 1.02 0.1 544 2894 exclusion phecode
302.1 Decreased libido Mental Disorders 0.847 0.683 – 1.05 0.132 97 1003 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.914 0.86 – 0.972 0.00429 1620 4752 exclusion phecode
303.1 Dissociative disorder Mental Disorders 1.14 0.788 – 1.64 0.492 32 423 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.906 0.851 – 0.964 0.00198 1550 4697 exclusion phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.808 0.662 – 0.987 0.0369 120 1144 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.98 0.864 – 1.11 0.751 312 3000 exclusion phecode
304 Adjustment reaction Mental Disorders 1.08 1 – 1.17 0.0372 930 4959 exclusion phecode
305.2 Eating disorder Mental Disorders 1.23 1.03 – 1.47 0.0252 145 2340 exclusion phecode
306 Other mental disorder Mental Disorders 1.03 0.93 – 1.14 0.57 464 3668 exclusion phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.04 0.869 – 1.25 0.656 156 1234 exclusion phecode
306.9 Tension headache Mental Disorders 0.986 0.842 – 1.16 0.866 189 2011 exclusion phecode
312 Conduct disorders Mental Disorders 1.17 0.909 – 1.52 0.218 74 661 exclusion phecode
312.3 Impulse control disorder Mental Disorders 0.842 0.545 – 1.3 0.44 23 218 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 1.15 1.04 – 1.27 0.00728 467 4203 exclusion phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1.16 1.04 – 1.29 0.00611 423 3835 exclusion phecode
313.2 Tics and stuttering Mental Disorders 1.03 0.649 – 1.63 0.903 23 217 exclusion phecode
313.3 Autism Mental Disorders 0.779 0.451 – 1.35 0.37 12 202 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.04 0.879 – 1.23 0.648 167 1581 exclusion phecode
315.1 Learning disorder Mental Disorders 0.977 0.656 – 1.45 0.91 25 273 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.916 0.7 – 1.2 0.525 62 604 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.31 1.22 – 1.41 3.65e-14 963 7539 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.01 0.844 – 1.2 0.944 153 1360 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.26 1.16 – 1.37 6.9e-08 671 4789 exclusion phecode
317.1 Alcoholism Mental Disorders 1.26 1.15 – 1.38 1.02e-06 561 3801 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.2 0.948 – 1.53 0.127 81 651 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.35 1.28 – 1.42 1.52e-28 2004 8160 exclusion phecode
320 Meningitis Neurological 1.09 0.882 – 1.34 0.429 101 872 exclusion phecode
323 Encephalitis Neurological 1.28 0.933 – 1.75 0.126 45 392 exclusion phecode
323.8 Encephalitis, non-infectious Neurological 1.2 0.848 – 1.7 0.305 39 330 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.11 0.837 – 1.47 0.474 52 626 exclusion phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 0.936 0.452 – 1.94 0.86 10 118 exclusion phecode
327 Sleep disorders Neurological 1.05 0.996 – 1.1 0.0732 2171 8803 exclusion phecode
327.1 Hypersomnia Neurological 1.01 0.888 – 1.15 0.88 266 5126 exclusion phecode
327.3 Sleep apnea Neurological 0.999 0.929 – 1.07 0.983 898 8640 exclusion phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1.1 0.883 – 1.38 0.384 81 1103 exclusion phecode
327.32 Obstructive sleep apnea Neurological 0.98 0.901 – 1.07 0.644 639 8241 exclusion phecode
327.4 Insomnia Neurological 1.06 0.992 – 1.13 0.0847 1270 8485 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.05 0.927 – 1.19 0.428 286 3274 exclusion phecode
327.5 Parasomnia Neurological 1.08 0.856 – 1.37 0.511 74 1455 exclusion phecode
327.6 Circadian rhythm sleep disorder Neurological 0.93 0.694 – 1.25 0.63 54 740 exclusion phecode
327.7 Sleep related movement disorders Neurological 0.999 0.884 – 1.13 0.986 304 4527 exclusion phecode
327.71 Restless legs syndrome Neurological 1 0.879 – 1.14 0.972 263 4037 exclusion phecode
327.72 Sleep related leg cramps Neurological 0.932 0.573 – 1.52 0.777 18 181 exclusion phecode
331 Other cerebral degenerations Neurological 1.09 0.923 – 1.28 0.319 175 1452 exclusion phecode
331.1 Hydrocephalus Neurological 1.03 0.802 – 1.32 0.816 69 663 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.15 0.932 – 1.42 0.192 105 817 exclusion phecode
332 Parkinson's disease Neurological 0.997 0.803 – 1.24 0.976 99 706 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.01 0.921 – 1.1 0.902 607 5909 exclusion phecode
333.1 Essential tremor Neurological 1.03 0.868 – 1.22 0.753 163 1443 exclusion phecode
333.2 Myoclonus Neurological 1.16 0.845 – 1.59 0.36 39 365 exclusion phecode
333.4 Torsion dystonia Neurological 0.991 0.805 – 1.22 0.929 113 785 exclusion phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 0.893 0.592 – 1.35 0.588 29 168 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.06 0.914 – 1.23 0.445 223 2251 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.25 0.757 – 2.05 0.386 21 164 exclusion phecode
334.2 Anterior horn cell disease Neurological 1.06 0.684 – 1.66 0.783 25 213 exclusion phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 0.985 0.558 – 1.74 0.958 17 119 exclusion phecode
335 Multiple sclerosis Neurological 1.04 0.848 – 1.29 0.683 101 931 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.12 0.961 – 1.3 0.147 203 1628 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.59 1.23 – 2.06 0.000445 73 560 exclusion phecode
338 Pain Neurological 1.09 1.05 – 1.14 1.73e-05 4506 6507 exclusion phecode
338.1 Acute pain Neurological 1.11 1.06 – 1.16 3.48e-06 3556 6458 exclusion phecode
338.2 Chronic pain Neurological 1.12 1.06 – 1.18 2.69e-05 2162 6474 exclusion phecode
339 Other headache syndromes Neurological 1.05 1 – 1.11 0.0419 2155 8099 exclusion phecode
340 Migraine Neurological 1.06 1 – 1.12 0.0448 1690 7395 exclusion phecode
340.1 Migrain with aura Neurological 1.13 1.05 – 1.21 0.00152 915 6012 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.07 0.748 – 1.52 0.72 34 302 exclusion phecode
342 Hemiplegia Neurological 1.18 0.966 – 1.44 0.105 110 966 exclusion phecode
343 Infantile cerebral palsy Neurological 1.2 0.807 – 1.8 0.362 25 246 exclusion phecode
344 Other paralytic syndromes Neurological 1.24 1.05 – 1.46 0.0107 171 1436 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.09 1 – 1.18 0.0445 654 5981 exclusion phecode
345.1 Epilepsy Neurological 1.03 0.885 – 1.2 0.681 194 1787 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.06 0.806 – 1.4 0.662 57 582 exclusion phecode
345.12 Partial epilepsy Neurological 0.987 0.82 – 1.19 0.888 138 1235 exclusion phecode
345.3 Convulsions Neurological 1.11 1.02 – 1.21 0.0158 620 5634 exclusion phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.978 0.704 – 1.36 0.897 40 423 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.04 0.927 – 1.17 0.496 338 3127 exclusion phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.947 0.641 – 1.4 0.782 28 262 exclusion phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 1.32 0.814 – 2.13 0.261 19 257 exclusion phecode
347 Cataplexy and narcolepsy Neurological 1.02 0.65 – 1.61 0.922 20 250 exclusion phecode
348 Other conditions of brain Neurological 1.12 1.01 – 1.24 0.0324 425 4047 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.03 0.893 – 1.19 0.674 215 2071 exclusion phecode
348.4 Cerebral cysts Neurological 0.88 0.66 – 1.17 0.38 53 566 exclusion phecode
348.7 Coma Neurological 1.3 0.988 – 1.71 0.0608 57 529 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.41 1.21 – 1.65 1.7e-05 195 1750 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.01 0.921 – 1.11 0.837 532 5180 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.13 0.983 – 1.3 0.0842 234 2163 exclusion phecode
350 Abnormal movement Neurological 1.07 1.01 – 1.13 0.033 1494 9072 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.07 0.991 – 1.16 0.0828 750 6804 exclusion phecode
350.2 Abnormality of gait Neurological 1.08 0.996 – 1.16 0.0632 815 6558 exclusion phecode
350.3 Lack of coordination Neurological 1.03 0.908 – 1.17 0.654 293 2332 exclusion phecode
350.5 Abnormal reflex Neurological 1.2 0.87 – 1.66 0.265 43 453 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.986 0.804 – 1.21 0.896 118 1103 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.06 1 – 1.13 0.0452 1352 8345 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.11 0.995 – 1.24 0.0607 379 4003 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.08 0.894 – 1.31 0.417 125 1317 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.08 0.919 – 1.28 0.338 161 1792 exclusion phecode
353 Nerve root and plexus disorders Neurological 1.1 1.02 – 1.19 0.0118 843 7874 exclusion phecode
353.1 Nerve plexus lesions Neurological 1.03 0.84 – 1.27 0.75 110 956 exclusion phecode
353.2 Nerve root lesions Neurological 1.17 0.76 – 1.79 0.482 24 257 exclusion phecode
355 Complex regional/central pain syndrome Neurological 1.08 0.896 – 1.29 0.431 131 1290 exclusion phecode
355.1 Chronic pain syndrome Neurological 1.32 1.13 – 1.55 0.000483 181 1965 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.11 0.995 – 1.23 0.0627 395 4283 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.13 1.04 – 1.23 0.00573 623 6312 exclusion phecode
358 Myoneural disorders Neurological 1.11 0.968 – 1.27 0.134 248 2514 exclusion phecode
358.1 Myasthenia gravis Neurological 0.903 0.599 – 1.36 0.627 26 245 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.975 0.862 – 1.1 0.693 309 2559 exclusion phecode
359.1 Muscular dystrophies Neurological 1.12 0.635 – 1.98 0.691 22 153 exclusion phecode
359.2 Myopathy Neurological 0.968 0.854 – 1.1 0.613 294 2454 exclusion phecode
360 Disorders of the globe Sense Organs 1.01 0.688 – 1.5 0.944 30 266 exclusion phecode
360.2 Progressive myopia Sense Organs 0.747 0.46 – 1.21 0.236 19 128 exclusion phecode
361 Retinal detachments and defects Sense Organs 1.03 0.866 – 1.22 0.765 156 1427 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.931 0.708 – 1.22 0.605 65 551 exclusion phecode
362 Other retinal disorders Sense Organs 0.979 0.902 – 1.06 0.623 747 4729 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.918 0.825 – 1.02 0.12 450 3086 exclusion phecode
362.21 Macular degeneration, dry Sense Organs 0.846 0.663 – 1.08 0.179 89 722 exclusion phecode
362.22 Macular degeneration, wet Sense Organs 0.802 0.527 – 1.22 0.303 34 253 exclusion phecode
362.23 Cystoid macular degeneration of retina Sense Organs 0.948 0.754 – 1.19 0.644 88 800 exclusion phecode
362.26 Macular puckering of retina Sense Organs 0.855 0.724 – 1.01 0.0653 173 1667 exclusion phecode
362.27 Drusen (degenerative) of retina Sense Organs 1.05 0.849 – 1.29 0.672 114 930 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.925 0.826 – 1.04 0.174 403 2769 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.11 0.94 – 1.3 0.224 174 1727 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1.34 1.07 – 1.67 0.0112 87 771 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.903 0.747 – 1.09 0.295 134 1199 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.896 0.723 – 1.11 0.319 97 793 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.955 0.707 – 1.29 0.762 50 491 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.05 0.787 – 1.39 0.751 62 476 exclusion phecode
362.9 Retinal edema Sense Organs 0.868 0.657 – 1.15 0.321 59 565 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.883 0.718 – 1.09 0.241 114 962 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.866 0.674 – 1.11 0.263 73 644 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.05 0.917 – 1.19 0.509 283 2369 exclusion phecode
364.1 Corneal opacity Sense Organs 0.852 0.685 – 1.06 0.151 104 821 exclusion phecode
364.2 Corneal edema Sense Organs 1.15 0.747 – 1.77 0.522 22 244 exclusion phecode
364.4 Corneal degenerations Sense Organs 1.04 0.855 – 1.27 0.679 118 907 exclusion phecode
364.41 Keratoconus Sense Organs 0.663 0.406 – 1.08 0.0996 21 155 exclusion phecode
364.5 Corneal dystrophy Sense Organs 1.06 0.86 – 1.3 0.589 106 998 exclusion phecode
364.51 Fuchs' dystrophy Sense Organs 1.15 0.866 – 1.54 0.327 60 530 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.751 0.441 – 1.28 0.292 17 188 exclusion phecode
365 Glaucoma Sense Organs 0.966 0.881 – 1.06 0.464 573 4343 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 0.99 0.832 – 1.18 0.905 166 1308 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.819 0.646 – 1.04 0.0983 93 729 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.822 0.611 – 1.11 0.197 67 484 exclusion phecode
366 Cataract Sense Organs 0.997 0.938 – 1.06 0.913 1738 5909 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.962 0.726 – 1.28 0.789 56 430 exclusion phecode
366.2 Senile cataract Sense Organs 0.969 0.901 – 1.04 0.398 1076 5140 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.941 0.894 – 0.991 0.0206 2073 8929 exclusion phecode
367.1 Myopia Sense Organs 0.897 0.842 – 0.957 0.000973 1236 8271 exclusion phecode
367.2 Astigmatism Sense Organs 0.905 0.843 – 0.973 0.0066 963 7507 exclusion phecode
367.8 Hypermetropia Sense Organs 0.928 0.837 – 1.03 0.154 439 4193 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.09 0.955 – 1.24 0.205 276 2785 exclusion phecode
368 Visual disturbances Sense Organs 1.03 0.973 – 1.1 0.273 1304 9189 exclusion phecode
368.1 Amblyopia Sense Organs 1.15 0.958 – 1.38 0.133 142 1495 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.02 0.893 – 1.16 0.772 257 2306 exclusion phecode
368.3 Anisometropia Sense Organs 0.827 0.624 – 1.1 0.187 57 494 exclusion phecode
368.4 Visual field defects Sense Organs 0.946 0.816 – 1.1 0.46 202 2398 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.969 0.845 – 1.11 0.658 246 2456 exclusion phecode
368.91 Psychophysical visual disturbances Sense Organs 1.09 0.717 – 1.64 0.698 30 248 exclusion phecode
369 Infection of the eye Sense Organs 0.898 0.829 – 0.971 0.0072 768 6955 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.853 0.697 – 1.04 0.123 126 1209 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.9 0.826 – 0.98 0.0152 653 6187 exclusion phecode
370 Keratitis Sense Organs 0.889 0.793 – 0.997 0.0439 363 3031 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.827 0.63 – 1.08 0.17 73 497 exclusion phecode
370.2 Superficial keratitis Sense Organs 0.9 0.747 – 1.08 0.264 135 1226 exclusion phecode
370.3 Keratoconjunctivitis Sense Organs 1.01 0.851 – 1.19 0.95 170 1469 exclusion phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.879 0.649 – 1.19 0.402 51 429 exclusion phecode
371 Inflammation of the eye Sense Organs 0.939 0.877 – 1.01 0.0724 1061 7190 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1 0.828 – 1.21 0.996 126 1173 exclusion phecode
371.2 Conjunctivitis, noninfectious Sense Organs 1.01 0.87 – 1.17 0.902 208 2101 exclusion phecode
371.21 Allergic conjunctivitis Sense Organs 0.983 0.835 – 1.16 0.836 171 1761 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.917 0.849 – 0.991 0.0283 827 5881 exclusion phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 1.05 0.759 – 1.47 0.75 45 323 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.04 0.914 – 1.19 0.542 270 2280 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.936 0.859 – 1.02 0.13 666 5197 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.853 0.691 – 1.05 0.139 104 867 exclusion phecode
374.2 Lagophthalmos Sense Organs 1.25 0.968 – 1.61 0.0868 71 518 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.993 0.865 – 1.14 0.923 248 2311 exclusion phecode
374.6 Dermatochalasis Sense Organs 0.914 0.783 – 1.07 0.252 193 2010 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.984 0.913 – 1.06 0.678 897 5809 exclusion phecode
375.1 Dry eyes Sense Organs 0.99 0.92 – 1.07 0.787 970 5921 exclusion phecode
375.2 Epiphora Sense Organs 0.946 0.766 – 1.17 0.606 109 943 exclusion phecode
376 Disorders of the orbit Sense Organs 1.08 0.857 – 1.36 0.514 85 816 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.08 0.93 – 1.27 0.301 187 2041 exclusion phecode
377.1 Optic atrophy Sense Organs 1.04 0.795 – 1.36 0.777 61 600 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.13 0.929 – 1.37 0.223 118 1325 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.09 0.966 – 1.23 0.163 308 2832 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.04 0.898 – 1.22 0.569 195 1886 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.02 0.737 – 1.4 0.924 44 362 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.04 0.82 – 1.32 0.737 83 745 exclusion phecode
379 Other disorders of eye Sense Organs 0.962 0.898 – 1.03 0.264 1109 6488 exclusion phecode
379.1 Scleritis and episcleritis Sense Organs 0.76 0.546 – 1.06 0.103 45 414 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.946 0.872 – 1.03 0.177 783 4805 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.763 0.518 – 1.12 0.172 38 278 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.07 0.819 – 1.4 0.617 62 614 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.1 0.858 – 1.42 0.443 73 591 exclusion phecode
379.51 Pigmentary iris degeneration Sense Organs 0.626 0.352 – 1.11 0.111 18 138 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.957 0.836 – 1.1 0.531 268 2541 exclusion phecode
380 Disorders of external ear Sense Organs 0.941 0.856 – 1.03 0.207 533 4433 exclusion phecode
380.1 Otitis externa Sense Organs 0.909 0.802 – 1.03 0.131 292 3392 exclusion phecode
380.4 Impacted cerumen Sense Organs 0.919 0.842 – 1 0.0605 622 5170 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.02 0.956 – 1.1 0.488 984 8885 exclusion phecode
381.1 Otitis media Sense Organs 1.02 0.943 – 1.11 0.587 692 7540 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.04 0.949 – 1.14 0.41 570 6551 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.965 0.872 – 1.07 0.497 456 4389 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 1.04 0.731 – 1.49 0.816 30 367 exclusion phecode
381.9 Otorrhea Sense Organs 1.37 1.07 – 1.76 0.0136 82 892 exclusion phecode
382 Otalgia Sense Organs 0.988 0.894 – 1.09 0.808 473 4795 exclusion phecode
383 Otosclerosis Sense Organs 1.15 0.821 – 1.6 0.421 33 289 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 0.96 0.79 – 1.17 0.684 126 1334 exclusion phecode
384.1 Myringitis Sense Organs 0.612 0.316 – 1.19 0.147 13 126 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 0.994 0.802 – 1.23 0.953 100 1050 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.952 0.782 – 1.16 0.625 115 1063 exclusion phecode
385.3 Cholesteatoma Sense Organs 0.975 0.768 – 1.24 0.833 77 704 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.963 0.699 – 1.33 0.82 42 313 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.931 0.833 – 1.04 0.203 389 4144 exclusion phecode
386.1 Meniere's disease Sense Organs 0.934 0.719 – 1.21 0.608 69 699 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.907 0.802 – 1.03 0.118 313 3465 exclusion phecode
386.21 Central origin vertigo Sense Organs 0.885 0.769 – 1.02 0.0899 239 2681 exclusion phecode
386.3 Labyrinthitis Sense Organs 0.894 0.789 – 1.01 0.0757 305 3323 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.03 0.969 – 1.09 0.371 1533 8939 exclusion phecode
388 Other disorders of ear Sense Organs 1.06 0.922 – 1.22 0.408 235 2220 exclusion phecode
389 Hearing loss Sense Organs 1.01 0.96 – 1.07 0.624 1750 9108 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.96 0.89 – 1.03 0.283 866 6253 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.04 0.902 – 1.19 0.605 231 2287 exclusion phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.999 0.71 – 1.41 0.997 45 353 exclusion phecode
389.4 Tinnitus Sense Organs 0.992 0.904 – 1.09 0.867 536 4740 exclusion phecode
389.5 Disorders of acoustic nerve Sense Organs 1.43 0.983 – 2.09 0.0612 35 268 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.05 0.926 – 1.19 0.453 313 2691 exclusion phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 0.943 0.732 – 1.22 0.65 71 628 exclusion phecode
394.2 Mitral valve disease Circulatory System 0.958 0.773 – 1.19 0.692 103 958 exclusion phecode
394.3 Aortic valve disease Circulatory System 0.94 0.634 – 1.39 0.759 25 304 exclusion phecode
394.4 Acute rheumatic heart disease Circulatory System 0.836 0.48 – 1.46 0.526 11 124 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.08 0.902 – 1.3 0.387 146 1151 exclusion phecode
395 Heart valve disorders Circulatory System 1.08 1.01 – 1.17 0.0359 885 6001 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.01 0.918 – 1.11 0.865 538 4304 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.21 1.08 – 1.36 0.000982 378 3214 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.06 0.863 – 1.29 0.595 121 1016 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.29 0.861 – 1.94 0.215 29 245 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.1 0.943 – 1.28 0.226 205 2036 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.08 1.01 – 1.15 0.0289 1089 7743 exclusion phecode
401 Hypertension Circulatory System 1.17 1.12 – 1.23 2.08e-10 3346 7626 exclusion phecode
401.1 Essential hypertension Circulatory System 1.17 1.11 – 1.23 4.34e-10 3302 7627 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.39 1.26 – 1.53 1.36e-11 559 4287 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.11 0.915 – 1.35 0.282 115 1846 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.45 1.31 – 1.62 5.51e-12 433 3799 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.29 1.17 – 1.43 3.42e-07 489 4747 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.2 1.13 – 1.28 1.55e-08 1399 6875 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.976 0.802 – 1.19 0.804 114 1634 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.23 1.12 – 1.35 8.49e-06 581 4475 exclusion phecode
411.3 Angina pectoris Circulatory System 1.15 1.02 – 1.29 0.0192 351 3742 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.2 1.12 – 1.29 1.57e-07 1170 6026 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.05 0.677 – 1.64 0.815 22 310 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.23 1.14 – 1.32 1.31e-07 935 5489 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.12 0.884 – 1.41 0.356 78 862 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.17 1.07 – 1.29 0.00105 537 4888 exclusion phecode
414.2 ASCVD Circulatory System 1.02 0.829 – 1.26 0.852 105 1390 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.19 1.09 – 1.3 0.000175 568 6409 exclusion phecode
415.1 Acute pulmonary heart disease Circulatory System 1.14 1.01 – 1.29 0.0317 307 4016 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.14 1.01 – 1.29 0.0332 306 3996 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.25 1.11 – 1.41 0.00025 325 3624 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.29 1.07 – 1.55 0.00665 141 1459 exclusion phecode
416 Cardiomegaly Circulatory System 1.22 1.05 – 1.4 0.00803 223 2598 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.06 1.01 – 1.11 0.0237 2663 8303 exclusion phecode
418.1 Precordial pain Circulatory System 1.04 0.914 – 1.19 0.539 257 2916 exclusion phecode
420 Carditis Circulatory System 1.05 0.929 – 1.18 0.455 325 3199 exclusion phecode
420.1 Myocarditis Circulatory System 0.996 0.586 – 1.7 0.99 16 212 exclusion phecode
420.2 Pericarditis Circulatory System 1.06 0.902 – 1.25 0.465 176 1693 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.04 0.763 – 1.42 0.802 43 368 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.13 0.71 – 1.8 0.605 21 235 exclusion phecode
420.3 Endocarditis Circulatory System 1.05 0.886 – 1.24 0.581 162 1555 exclusion phecode
425 Cardiomyopathy Circulatory System 1.17 1.05 – 1.31 0.0056 365 3873 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.16 1.03 – 1.3 0.0116 347 3682 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.99 0.673 – 1.46 0.96 30 393 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.3 0.885 – 1.91 0.182 26 421 exclusion phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.14 0.886 – 1.46 0.309 72 673 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.74 1.11 – 2.73 0.0164 24 212 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.14 1.08 – 1.2 2.12e-06 2393 6433 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.11 0.976 – 1.27 0.109 282 2269 exclusion phecode
426.21 First degree AV block Circulatory System 1.03 0.877 – 1.22 0.686 184 1698 exclusion phecode
426.22 Mobitz II AV block Circulatory System 1.2 0.623 – 2.3 0.589 11 121 exclusion phecode
426.23 Second degree AV block Circulatory System 1.13 0.805 – 1.6 0.472 41 380 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1.05 0.823 – 1.33 0.707 85 744 exclusion phecode
426.25 Other heart block Circulatory System 1.37 0.96 – 1.94 0.0828 38 337 exclusion phecode
426.3 Bundle branch block Circulatory System 1.12 1 – 1.26 0.0499 378 2927 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.05 0.911 – 1.21 0.504 235 2178 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.19 0.996 – 1.41 0.0552 152 1610 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.992 0.649 – 1.52 0.971 24 216 exclusion phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.15 1.08 – 1.21 1.54e-06 2072 6305 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.3 1.08 – 1.57 0.00575 137 1431 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.15 1.02 – 1.31 0.0263 305 2302 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.23 1.05 – 1.44 0.0125 189 1569 exclusion phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.21 1.02 – 1.44 0.0306 150 1374 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.06 1.01 – 1.11 0.00925 3759 6569 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.12 1.01 – 1.23 0.0269 517 4083 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.06 0.942 – 1.18 0.346 360 3264 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.21 1.04 – 1.4 0.0127 212 1952 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.08 0.992 – 1.17 0.0773 880 4073 exclusion phecode
427.21 Atrial fibrillation Circulatory System 1.06 0.977 – 1.15 0.158 850 3984 exclusion phecode
427.22 Atrial flutter Circulatory System 0.997 0.873 – 1.14 0.969 270 2103 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.1 1.04 – 1.17 0.000455 1873 6497 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.04 0.832 – 1.31 0.708 89 1045 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.05 0.736 – 1.51 0.777 31 405 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.09 0.846 – 1.39 0.521 76 797 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.05 0.989 – 1.12 0.109 1413 6465 exclusion phecode
427.6 Premature beats Circulatory System 0.966 0.871 – 1.07 0.515 451 3494 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1.03 0.862 – 1.23 0.742 144 1322 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.15 1.08 – 1.23 3.08e-05 1198 6476 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.07 0.911 – 1.27 0.395 174 1536 exclusion phecode
427.9 Palpitations Circulatory System 0.949 0.885 – 1.02 0.141 1079 6085 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.25 1.14 – 1.36 4.17e-07 692 5011 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.23 1.13 – 1.35 5.37e-06 592 4695 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.27 1.16 – 1.39 6.03e-07 568 4489 exclusion phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.25 1.11 – 1.42 0.000315 312 2812 exclusion phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.26 1.08 – 1.46 0.00249 207 2667 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.08 1.03 – 1.13 0.00168 2642 8036 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.26 1.1 – 1.45 0.000956 243 2297 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.17 1.09 – 1.25 6.42e-06 1140 6729 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.06 1.01 – 1.12 0.0165 2144 7990 exclusion phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.2 0.995 – 1.46 0.0561 123 1402 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.04 0.887 – 1.22 0.628 183 1622 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.26 0.958 – 1.65 0.0981 60 542 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.03 0.815 – 1.3 0.808 87 759 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.07 0.834 – 1.39 0.578 73 525 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.15 1.08 – 1.23 3.99e-05 1116 6795 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.16 1.04 – 1.29 0.00762 418 3096 exclusion phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.06 0.799 – 1.4 0.7 60 505 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 0.772 0.449 – 1.33 0.35 16 154 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.21 1.09 – 1.33 0.00019 482 4311 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.22 1.11 – 1.35 8.42e-05 467 4173 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.12 1.02 – 1.23 0.0175 558 4590 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.14 1.03 – 1.25 0.0124 483 4143 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.13 0.928 – 1.38 0.222 123 1079 exclusion phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.12 0.881 – 1.42 0.353 76 904 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.15 0.957 – 1.38 0.136 139 1421 exclusion phecode
440 Atherosclerosis Circulatory System 1.19 1.08 – 1.32 0.000562 483 3834 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.1 0.822 – 1.46 0.529 53 473 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.07 0.945 – 1.22 0.278 289 2602 exclusion phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.35 1.01 – 1.8 0.0453 57 444 exclusion phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.04 0.889 – 1.21 0.65 202 1833 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.23 1.03 – 1.46 0.0205 146 1519 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.22 1.02 – 1.46 0.0297 141 1086 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.1 0.842 – 1.44 0.479 64 493 exclusion phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.25 0.929 – 1.69 0.14 49 341 exclusion phecode
442 Other aneurysm Circulatory System 1.16 1.05 – 1.27 0.00214 538 4204 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.16 1.03 – 1.3 0.0113 359 3044 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.07 0.928 – 1.24 0.341 231 1842 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 0.923 0.623 – 1.37 0.691 26 331 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.21 0.806 – 1.81 0.36 26 317 exclusion phecode
442.4 Arterial dissection Circulatory System 0.99 0.719 – 1.36 0.952 41 360 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.26 1 – 1.59 0.0481 97 829 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.08 1 – 1.18 0.0496 751 5181 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 0.969 0.849 – 1.11 0.636 299 1780 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.65 1.06 – 2.59 0.0283 25 321 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.11 1.02 – 1.21 0.0187 633 4524 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.16 1.05 – 1.28 0.00316 470 3653 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.13 0.972 – 1.32 0.11 205 1687 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.04 0.818 – 1.31 0.767 85 563 exclusion phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 0.904 0.622 – 1.31 0.597 33 254 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.07 0.868 – 1.31 0.537 112 996 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.837 0.574 – 1.22 0.357 29 233 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.28 0.721 – 2.27 0.399 17 155 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.03 0.8 – 1.33 0.805 74 611 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.15 1.05 – 1.26 0.00303 541 4593 exclusion phecode
447.1 Stricture of artery Circulatory System 1.2 0.987 – 1.45 0.068 127 1103 exclusion phecode
447.7 Aortic ectasia Circulatory System 1.15 0.946 – 1.4 0.159 110 1448 exclusion phecode
448 Disease of capillaries Circulatory System 0.84 0.746 – 0.947 0.00426 338 2641 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.1 0.991 – 1.22 0.0739 431 4714 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.892 0.751 – 1.06 0.195 154 1664 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.985 0.698 – 1.39 0.932 39 565 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1.07 0.996 – 1.15 0.0649 915 7002 exclusion phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1.12 0.796 – 1.59 0.507 32 571 exclusion phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1.05 0.963 – 1.15 0.264 596 6075 exclusion phecode
452.8 Postphlebitic syndrome Circulatory System 0.557 0.35 – 0.885 0.0132 21 348 exclusion phecode
453 Chronic venous hypertension Circulatory System 0.921 0.668 – 1.27 0.613 47 476 exclusion phecode
454 Varicose veins Circulatory System 1.03 0.947 – 1.13 0.46 608 5675 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1.02 0.922 – 1.12 0.755 514 4894 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.958 0.848 – 1.08 0.489 316 3463 exclusion phecode
455 Hemorrhoids Circulatory System 0.949 0.89 – 1.01 0.104 1282 6964 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.943 0.861 – 1.03 0.205 567 5684 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.08 0.961 – 1.21 0.205 364 3134 exclusion phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.21 0.91 – 1.62 0.186 55 598 exclusion phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.06 0.944 – 1.2 0.314 336 2996 exclusion phecode
458 Hypotension Circulatory System 1.24 1.16 – 1.33 9.68e-11 1176 7346 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.25 1.11 – 1.42 0.000398 332 2790 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.24 1.08 – 1.43 0.00242 240 2177 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.26 1.18 – 1.35 5.53e-11 1063 7007 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.14 1.07 – 1.21 1.67e-05 1488 8249 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.16 0.992 – 1.37 0.0618 198 1796 exclusion phecode
459.7 Blood vessel replaced Circulatory System 1.3 1.13 – 1.48 0.000136 270 2697 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.1 1.03 – 1.18 0.00269 1216 7763 exclusion phecode
464 Acute sinusitis Respiratory 0.96 0.897 – 1.03 0.243 1058 7669 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.963 0.917 – 1.01 0.134 2314 8379 exclusion phecode
465.2 Acute pharyngitis Respiratory 0.929 0.874 – 0.988 0.0189 1387 7845 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.946 0.764 – 1.17 0.611 99 1091 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.01 0.909 – 1.11 0.898 447 4242 exclusion phecode
471 Nasal polyps Respiratory 0.924 0.769 – 1.11 0.404 128 1347 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.911 0.817 – 1.02 0.0971 386 4089 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.09 1.01 – 1.18 0.0252 765 5620 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.01 0.563 – 1.8 0.983 15 141 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.1 0.924 – 1.31 0.283 152 1442 exclusion phecode
473.4 Voice disturbance Respiratory 1.1 1.01 – 1.21 0.025 621 4837 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1.06 0.932 – 1.2 0.378 289 2465 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.04 0.859 – 1.26 0.686 129 1165 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.06 0.918 – 1.22 0.425 220 2021 exclusion phecode
475 Chronic sinusitis Respiratory 1.03 0.957 – 1.1 0.456 987 6534 exclusion phecode
475.9 Postnasal drip Respiratory 0.98 0.839 – 1.15 0.804 196 1995 exclusion phecode
476 Allergic rhinitis Respiratory 0.969 0.925 – 1.02 0.185 2895 6585 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.17 1.02 – 1.33 0.0198 266 2574 exclusion phecode
478 Throat pain Respiratory 1.19 0.975 – 1.45 0.0879 120 1024 exclusion phecode
479 Other upper respiratory disease Respiratory 1.08 1.01 – 1.15 0.0156 1311 6567 exclusion phecode
480 Pneumonia Respiratory 1.13 1.07 – 1.21 7.09e-05 1287 8722 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.19 1.05 – 1.35 0.00551 309 2487 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.3 1.08 – 1.57 0.00526 139 1193 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.34 0.971 – 1.86 0.0746 50 359 exclusion phecode
480.13 MRSA pneumonia Respiratory 1.53 0.918 – 2.54 0.103 20 272 exclusion phecode
480.2 Viral pneumonia Respiratory 1.31 0.94 – 1.81 0.112 41 379 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.47 1.06 – 2.03 0.0194 47 332 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.53 1.06 – 2.22 0.0237 39 297 exclusion phecode
481 Influenza Respiratory 1.04 0.921 – 1.19 0.494 298 3205 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.973 0.894 – 1.06 0.53 646 7069 exclusion phecode
495 Asthma Respiratory 1.1 1.04 – 1.16 0.000656 1770 8173 exclusion phecode
495.1 Chronic obstructive asthma Respiratory 1.21 0.936 – 1.57 0.144 66 857 exclusion phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 1.26 0.529 – 3.02 0.598 8 159 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.04 0.926 – 1.17 0.496 321 4419 exclusion phecode
496 Chronic airway obstruction Respiratory 1.33 1.24 – 1.42 1.32e-16 1192 6161 exclusion phecode
496.1 Emphysema Respiratory 1.4 1.27 – 1.54 2.73e-12 559 3825 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.43 1.33 – 1.55 1.52e-19 840 5653 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.47 1.35 – 1.59 3.82e-20 770 5285 exclusion phecode
496.3 Bronchiectasis Respiratory 1.17 0.992 – 1.39 0.0612 170 1143 exclusion phecode
497 Bronchitis Respiratory 1.12 1 – 1.26 0.0419 365 4623 exclusion phecode
498 Acute bronchospasm Respiratory 1.22 0.98 – 1.51 0.0753 97 1271 exclusion phecode
499 Cystic fibrosis Respiratory 1.21 0.898 – 1.62 0.212 57 408 exclusion phecode
500 Lung disease due to external agents Respiratory 1.39 1.14 – 1.71 0.00129 122 1106 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.53 0.938 – 2.49 0.0887 23 203 exclusion phecode
500.2 Pneumoconiosis Respiratory 1.14 0.56 – 2.34 0.711 10 121 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.44 1.22 – 1.71 2.91e-05 173 1183 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.05 0.886 – 1.24 0.585 165 1637 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.22 1.03 – 1.44 0.0218 164 1657 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.08 0.888 – 1.31 0.452 126 1197 exclusion phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 0.944 0.721 – 1.24 0.677 66 623 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.08 0.963 – 1.22 0.183 342 3215 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.18 1.09 – 1.28 8.41e-05 701 5222 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.17 1.08 – 1.28 0.000192 659 5524 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.23 1.11 – 1.36 4.26e-05 475 4713 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.22 1.13 – 1.31 6.07e-07 808 6265 exclusion phecode
509.1 Respiratory failure Respiratory 1.35 1.21 – 1.5 3.56e-08 427 3812 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.21 1.06 – 1.39 0.00534 269 2349 exclusion phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.19 1.06 – 1.32 0.00285 385 3241 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.28 1.14 – 1.45 6.01e-05 317 3416 exclusion phecode
510 Other diseases of lung Respiratory 1.12 1.05 – 1.19 0.000644 1194 7846 exclusion phecode
510.2 Lung transplant Respiratory 1.3 0.94 – 1.8 0.112 51 373 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.11 1.06 – 1.16 9.98e-07 3890 7132 exclusion phecode
512.1 Wheezing Respiratory 1.23 1.06 – 1.42 0.00541 215 3292 exclusion phecode
512.2 Painful respiration Respiratory 1.15 1.05 – 1.26 0.00321 552 5258 exclusion phecode
512.3 Abnormal chest sounds Respiratory 1.15 0.889 – 1.5 0.281 73 608 exclusion phecode
512.7 Shortness of breath Respiratory 1.16 1.1 – 1.22 9.66e-08 1926 7104 exclusion phecode
512.8 Cough Respiratory 1.08 1.02 – 1.14 0.00528 2033 7127 exclusion phecode
512.9 Other dyspnea Respiratory 1.12 1.06 – 1.18 2.51e-05 1997 7106 exclusion phecode
513 Respiratory abnormalities Respiratory 1.13 1.08 – 1.19 3.25e-07 2470 8537 exclusion phecode
513.3 Hypoventilation Respiratory 1.18 0.982 – 1.42 0.0772 128 1878 exclusion phecode
513.31 Apnea Respiratory 1.18 0.927 – 1.5 0.179 76 960 exclusion phecode
513.32 Orthopnea Respiratory 1.17 0.813 – 1.68 0.401 28 412 exclusion phecode
513.4 Hyperventilation Respiratory 1.49 1.18 – 1.89 0.000834 94 1120 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.38 1 – 1.9 0.0503 40 488 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.15 1.08 – 1.23 2.39e-05 1193 7434 exclusion phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 0.862 0.643 – 1.16 0.319 52 543 exclusion phecode
514.2 Solitary pulmonary nodule Respiratory 1.14 1.04 – 1.24 0.00297 652 5644 exclusion phecode
516 Abnormal sputum Respiratory 1.18 0.999 – 1.39 0.0517 169 1494 exclusion phecode
516.1 Hemoptysis Respiratory 1.14 0.952 – 1.38 0.151 137 1263 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.12 1.06 – 1.19 0.000114 1418 9074 exclusion phecode
519.1 Tracheostomy complications Respiratory 1.68 1.27 – 2.21 0.000248 64 431 exclusion phecode
519.2 Respiratory complications Respiratory 1.14 0.912 – 1.42 0.255 94 928 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.06 0.948 – 1.18 0.317 382 3472 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.18 1.1 – 1.26 2.79e-06 1037 7618 exclusion phecode
520 Disorders of tooth development Digestive 0.97 0.798 – 1.18 0.756 120 952 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.17 0.843 – 1.63 0.346 52 380 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.931 0.737 – 1.18 0.551 77 638 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.43 1.25 – 1.64 2.41e-07 250 1935 exclusion phecode
521.1 Dental caries Digestive 1.4 1.22 – 1.62 2.62e-06 234 1781 exclusion phecode
521.2 Dental abrasion, erosion and attrition Digestive 1.05 0.575 – 1.9 0.883 8 116 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.35 1.11 – 1.64 0.00246 111 1178 exclusion phecode
522.5 Periapical abscess Digestive 1.5 1.21 – 1.85 0.000161 95 1040 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.25 1.06 – 1.47 0.00914 163 1547 exclusion phecode
523.1 Gingivitis Digestive 1.15 0.81 – 1.63 0.44 38 340 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.42 1.1 – 1.82 0.00619 71 779 exclusion phecode
523.31 Acute periodontitis Digestive 1.34 1.03 – 1.75 0.0314 56 663 exclusion phecode
523.32 Chronic periodontitis Digestive 1.74 1.17 – 2.58 0.00611 30 246 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.04 0.868 – 1.25 0.674 160 1055 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.05 0.846 – 1.31 0.653 110 683 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.34 1.18 – 1.52 9.3e-06 278 2423 exclusion phecode
525.1 Loss of teeth or edentulism Digestive 1.37 1.1 – 1.69 0.00422 105 894 exclusion phecode
526 Diseases of the jaws Digestive 1.06 0.982 – 1.14 0.135 817 6561 exclusion phecode
526.1 Cysts of the jaws Digestive 0.714 0.539 – 0.946 0.0191 53 512 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.989 0.805 – 1.22 0.918 123 786 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.03 0.928 – 1.14 0.589 453 3884 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.994 0.887 – 1.11 0.912 371 3116 exclusion phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 1.06 0.915 – 1.22 0.458 237 2005 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 1.4 1.12 – 1.75 0.00283 104 654 exclusion phecode
526.8 Exostosis of jaw Digestive 1.53 0.878 – 2.67 0.134 21 98 exclusion phecode
526.9 Jaw disease NOS Digestive 1.13 0.96 – 1.34 0.138 173 1118 exclusion phecode
527 Diseases of the salivary glands Digestive 1.1 0.987 – 1.22 0.086 425 3834 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 0.957 0.565 – 1.62 0.869 14 141 exclusion phecode
527.2 Sialoadenitis Digestive 1.1 0.884 – 1.37 0.387 95 913 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.17 1.02 – 1.36 0.0293 226 1880 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.05 0.779 – 1.43 0.729 54 529 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.07 0.992 – 1.16 0.0768 751 5899 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.12 0.963 – 1.31 0.14 200 1559 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.29 0.95 – 1.76 0.103 51 490 exclusion phecode
528.12 Oral aphthae Digestive 0.904 0.698 – 1.17 0.445 69 559 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.74 1.33 – 2.28 4.52e-05 74 528 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.701 0.48 – 1.02 0.0662 33 296 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.844 0.529 – 1.35 0.479 23 176 exclusion phecode
528.5 Diseases of lips Digestive 1.02 0.849 – 1.24 0.799 142 1063 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.06 0.743 – 1.51 0.75 34 277 exclusion phecode
528.7 Sialolithiasis Digestive 1.34 0.962 – 1.86 0.0837 44 339 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.08 0.911 – 1.27 0.385 156 1409 exclusion phecode
529.1 Glossitis Digestive 1.21 0.833 – 1.76 0.315 30 268 exclusion phecode
529.6 Glossodynia Digestive 0.97 0.673 – 1.4 0.872 30 321 exclusion phecode
530 Diseases of esophagus Digestive 1.14 1.09 – 1.19 1.15e-08 3202 7330 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.14 1.09 – 1.19 4.24e-08 3046 7330 exclusion phecode
530.11 GERD Digestive 1.14 1.08 – 1.19 7.23e-08 2914 7329 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.26 1 – 1.58 0.0467 84 907 exclusion phecode
530.13 Barrett's esophagus Digestive 1.38 1.13 – 1.7 0.00203 106 1472 exclusion phecode
530.14 Reflux esophagitis Digestive 1.16 1.03 – 1.3 0.011 367 4224 exclusion phecode
530.15 Eosinophilic esophagitis Digestive 1.02 0.757 – 1.38 0.883 49 627 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.19 0.998 – 1.42 0.0524 137 1353 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1.24 1.07 – 1.43 0.00397 217 2006 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.22 1.01 – 1.47 0.0354 131 1344 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.926 0.653 – 1.31 0.666 43 257 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.93 1.21 – 3.07 0.00595 22 185 exclusion phecode
530.9 Heartburn Digestive 1.18 1.05 – 1.34 0.00693 300 3782 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.19 1.07 – 1.32 0.00106 435 4455 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.17 0.926 – 1.47 0.191 81 733 exclusion phecode
531.2 Gastric ulcer Digestive 1.25 1.1 – 1.44 0.000973 247 2646 exclusion phecode
531.3 Duodenal ulcer Digestive 1.12 0.907 – 1.37 0.297 99 883 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.2 1.02 – 1.42 0.0269 180 1724 exclusion phecode
531.5 Gastrojejunal ulcer Digestive 0.967 0.678 – 1.38 0.854 38 323 exclusion phecode
532 Dysphagia Digestive 1.28 1.2 – 1.36 1.02e-14 1388 6859 exclusion phecode
535 Gastritis and duodenitis Digestive 1.06 0.972 – 1.16 0.189 611 6299 exclusion phecode
535.1 Acute gastritis Digestive 1.21 1.06 – 1.39 0.00565 238 2623 exclusion phecode
535.2 Atrophic gastritis Digestive 0.936 0.735 – 1.19 0.593 76 786 exclusion phecode
535.6 Duodenitis Digestive 0.876 0.674 – 1.14 0.324 67 710 exclusion phecode
535.8 Other specified gastritis Digestive 1.04 0.874 – 1.23 0.686 142 1439 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.996 0.88 – 1.13 0.944 294 2905 exclusion phecode
536 Disorders of function of stomach Digestive 1.14 1.05 – 1.23 0.00128 771 6521 exclusion phecode
536.3 Gastroparesis Digestive 1.26 1.07 – 1.48 0.00544 184 1584 exclusion phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.39 1.15 – 1.68 0.00067 137 858 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.1 1 – 1.21 0.0438 544 4961 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.18 1.09 – 1.28 4.76e-05 746 6762 exclusion phecode
537.1 Lesions of stomach and duodenum Digestive 1.63 1.13 – 2.36 0.00911 34 309 exclusion phecode
539 Bariatric surgery Digestive 2.22 1.73 – 2.85 4.7e-10 73 3739 exclusion phecode
540 Appendiceal conditions Digestive 0.869 0.716 – 1.05 0.152 126 1222 exclusion phecode
540.1 Appendicitis Digestive 0.822 0.669 – 1.01 0.0626 110 1037 exclusion phecode
540.11 Acute appendicitis Digestive 0.837 0.67 – 1.04 0.116 95 855 exclusion phecode
550 Abdominal hernia Digestive 1.02 0.958 – 1.09 0.515 1207 8816 exclusion phecode
550.1 Inguinal hernia Digestive 0.907 0.818 – 1.01 0.0631 445 3017 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.12 1.01 – 1.24 0.0299 446 5737 exclusion phecode
550.3 Femoral hernia Digestive 0.817 0.594 – 1.12 0.215 51 272 exclusion phecode
550.4 Umbilical hernia Digestive 0.936 0.792 – 1.11 0.436 155 2658 exclusion phecode
550.5 Ventral hernia Digestive 1.12 0.999 – 1.26 0.0525 340 4744 exclusion phecode
550.6 Incisional hernia Digestive 1.16 0.989 – 1.35 0.0676 177 2826 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.17 1.05 – 1.29 0.00305 466 3704 exclusion phecode
555.1 Regional enteritis Digestive 1.27 1.13 – 1.44 0.000124 313 2269 exclusion phecode
555.2 Ulcerative colitis Digestive 1.06 0.93 – 1.21 0.38 273 2180 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 0.977 0.826 – 1.16 0.789 175 1300 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.21 1.02 – 1.45 0.0278 159 1371 exclusion phecode
556.1 Ulceration of intestine Digestive 1.22 1.01 – 1.46 0.0357 139 1217 exclusion phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 1.27 0.91 – 1.78 0.158 40 393 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.23 1.1 – 1.37 0.000226 381 4374 exclusion phecode
557.1 Celiac disease Digestive 1.07 0.896 – 1.28 0.445 155 1065 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.16 1.07 – 1.24 0.000116 893 6442 exclusion phecode
559 Ileostomy status Digestive 1.18 1.03 – 1.35 0.0172 248 2053 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.19 1.1 – 1.28 1.32e-05 792 5625 exclusion phecode
560.1 Paralytic ileus Digestive 1.13 1.01 – 1.26 0.0283 385 3274 exclusion phecode
560.2 Impaction of intestine Digestive 1.27 1.04 – 1.57 0.0224 111 930 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.18 0.943 – 1.49 0.145 90 613 exclusion phecode
560.4 Other intestinal obstruction Digestive 1.22 1.11 – 1.35 8.28e-05 482 3597 exclusion phecode
561 Symptoms involving digestive system Digestive 1.07 0.988 – 1.17 0.0941 672 5257 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1.01 0.94 – 1.09 0.768 1035 4936 exclusion phecode
562.1 Diverticulosis Digestive 1 0.933 – 1.08 0.917 1026 4925 exclusion phecode
562.2 Diverticulitis Digestive 1.13 0.989 – 1.3 0.0708 249 3143 exclusion phecode
564 Functional digestive disorders Digestive 1.14 1.08 – 1.19 1.59e-07 2747 6964 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.11 1.03 – 1.2 0.00458 904 5634 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.16 1.07 – 1.26 0.000463 685 5931 exclusion phecode
565 Anal and rectal conditions Digestive 0.995 0.922 – 1.07 0.887 818 6940 exclusion phecode
565.1 Anal and rectal polyp Digestive 0.861 0.75 – 0.989 0.0342 236 2505 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.26 1.12 – 1.42 0.000121 336 2915 exclusion phecode
568 Other disorders of peritoneum Digestive 1.16 1.03 – 1.29 0.0103 372 3676 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.21 1.06 – 1.38 0.00471 262 2676 exclusion phecode
569 Other disorders of intestine Digestive 1.12 1.06 – 1.19 4.83e-05 1700 8326 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.34 1.03 – 1.73 0.0272 81 697 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.26 1.12 – 1.42 0.000193 304 3101 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.18 1.09 – 1.28 5.72e-05 692 7454 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.17 1.07 – 1.27 0.00034 622 7333 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.26 1.08 – 1.48 0.00396 178 1964 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.36 0.964 – 1.91 0.0798 38 370 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.23 1.06 – 1.44 0.0075 201 1842 exclusion phecode
571.81 Portal hypertension Digestive 1.15 0.929 – 1.43 0.198 106 1127 exclusion phecode
572 Ascites (non malignant) Digestive 1.18 1.08 – 1.29 0.000264 575 5073 exclusion phecode
573 Other disorders of liver Digestive 1.11 1.04 – 1.19 0.00309 1049 7805 exclusion phecode
573.1 Chronic passive congestion of liver Digestive 1.45 0.973 – 2.15 0.0682 33 296 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.25 0.967 – 1.61 0.0882 71 550 exclusion phecode
573.3 Hepatomegaly Digestive 1.25 1.01 – 1.56 0.0447 93 1082 exclusion phecode
573.4 Acute and subacute necrosis of liver Digestive 1.26 0.986 – 1.62 0.0645 80 635 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.23 1.07 – 1.41 0.00386 232 1937 exclusion phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.15 1.05 – 1.25 0.00277 560 5842 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.11 1.02 – 1.22 0.019 572 6092 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.13 1.05 – 1.21 0.000728 969 7954 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.13 1.03 – 1.24 0.0127 520 7209 exclusion phecode
574.1 Cholelithiasis Digestive 1.12 1.01 – 1.24 0.0248 455 6806 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.07 0.8 – 1.44 0.635 46 772 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.924 0.728 – 1.17 0.518 77 1290 exclusion phecode
574.2 Calculus of bile duct Digestive 1.13 0.947 – 1.34 0.181 161 1979 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.3 1.08 – 1.56 0.00457 137 1871 exclusion phecode
575 Other biliary tract disease Digestive 1.13 1.03 – 1.24 0.0135 496 5142 exclusion phecode
575.1 Cholangitis Digestive 1.29 1.04 – 1.59 0.0193 101 731 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.29 1.09 – 1.51 0.00244 173 1349 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.766 0.554 – 1.06 0.105 40 529 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.18 0.999 – 1.38 0.0512 170 2192 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.21 1.07 – 1.36 0.00295 302 2508 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.896 0.676 – 1.19 0.447 56 590 exclusion phecode
577 Diseases of pancreas Digestive 1.19 1.09 – 1.31 0.000155 554 4716 exclusion phecode
577.1 Acute pancreatitis Digestive 1.34 1.18 – 1.52 6.27e-06 285 2551 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.54 1.27 – 1.86 8.11e-06 138 982 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.13 0.946 – 1.36 0.173 158 1167 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.09 1.02 – 1.17 0.0118 1007 8632 exclusion phecode
578.1 Hematemesis Digestive 1.35 1.1 – 1.65 0.00331 117 1060 exclusion phecode
578.2 Blood in stool Digestive 1.11 1.02 – 1.21 0.0214 600 5938 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.04 0.945 – 1.15 0.413 476 5034 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.15 1.02 – 1.29 0.0193 349 3224 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.12 1.05 – 1.21 0.00104 975 7967 exclusion phecode
579.2 Splenomegaly Digestive 1.25 1.03 – 1.51 0.0225 121 1577 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.14 1.02 – 1.29 0.0248 326 3092 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.26 1.12 – 1.42 0.000117 327 3423 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.32 1.06 – 1.65 0.0134 93 846 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.37 0.942 – 2.01 0.099 30 314 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.7 1.07 – 2.71 0.0241 17 241 exclusion phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.21 0.717 – 2.05 0.473 13 135 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.42 1.1 – 1.84 0.00686 71 621 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.17 0.85 – 1.61 0.337 37 466 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.32 1.15 – 1.51 4.85e-05 249 2607 exclusion phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.29 1.08 – 1.55 0.0054 138 1500 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.39 1.17 – 1.65 0.000156 147 1449 exclusion phecode
580.4 Renal sclerosis, NOS Genitourinary 1.31 1.03 – 1.67 0.0285 71 754 exclusion phecode
585 Renal failure Genitourinary 1.25 1.18 – 1.33 1.39e-12 1352 7675 exclusion phecode
585.1 Acute renal failure Genitourinary 1.32 1.22 – 1.43 1.72e-12 803 6037 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.28 1.09 – 1.5 0.00292 182 1711 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.25 1.16 – 1.34 1.08e-09 985 6716 exclusion phecode
585.31 Renal dialysis Genitourinary 1.38 1.18 – 1.63 9.3e-05 176 1530 exclusion phecode
585.32 End stage renal disease Genitourinary 1.47 1.27 – 1.69 8.09e-08 238 2054 exclusion phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.28 1.16 – 1.42 8.38e-07 492 4489 exclusion phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.3 1.12 – 1.52 0.000772 187 1901 exclusion phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.26 1.09 – 1.45 0.00178 232 2389 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.12 1.06 – 1.19 0.000118 1476 8474 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.18 0.942 – 1.47 0.151 86 891 exclusion phecode
586.11 Small kidney Genitourinary 1.22 0.905 – 1.65 0.19 45 515 exclusion phecode
586.12 Vesicoureteral reflux Genitourinary 1.03 0.758 – 1.39 0.87 40 401 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.04 0.916 – 1.19 0.515 257 2645 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.23 0.9 – 1.68 0.193 44 391 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.05 0.946 – 1.17 0.336 391 3829 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.42 1.23 – 1.64 1.11e-06 231 1742 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.35 1.17 – 1.56 4e-05 220 2000 exclusion phecode
588.1 Renal osteodystrophy Genitourinary 1.32 1.05 – 1.67 0.0178 85 582 exclusion phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.32 1.11 – 1.57 0.00138 155 1556 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.22 1.05 – 1.42 0.00887 210 2132 exclusion phecode
590 Pyelonephritis Genitourinary 1.08 0.958 – 1.22 0.205 326 3559 exclusion phecode
591 Urinary tract infection Genitourinary 1.03 0.976 – 1.08 0.312 2300 7506 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.04 0.96 – 1.13 0.335 740 5943 exclusion phecode
592.1 Cystitis Genitourinary 1.06 0.972 – 1.15 0.2 698 5747 exclusion phecode
592.11 Acute cystitis Genitourinary 1.08 0.971 – 1.2 0.158 421 4051 exclusion phecode
592.12 Chronic cystitis Genitourinary 1.14 0.84 – 1.55 0.399 49 587 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1 0.831 – 1.21 0.968 139 1166 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.966 0.734 – 1.27 0.802 62 490 exclusion phecode
593 Hematuria Genitourinary 1.03 0.956 – 1.1 0.481 970 7381 exclusion phecode
593.1 Gross hematuria Genitourinary 0.943 0.831 – 1.07 0.362 285 2873 exclusion phecode
593.2 Microscopic hematuria Genitourinary 1.04 0.902 – 1.21 0.568 229 2282 exclusion phecode
594 Urinary calculus Genitourinary 1.06 0.998 – 1.13 0.0586 1206 9137 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.06 0.989 – 1.13 0.104 1117 9085 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.12 0.881 – 1.41 0.363 80 715 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.02 0.887 – 1.16 0.818 234 3001 exclusion phecode
594.8 Renal colic Genitourinary 1.19 0.92 – 1.54 0.186 70 882 exclusion phecode
595 Hydronephrosis Genitourinary 1.23 1.1 – 1.37 0.00032 382 3817 exclusion phecode
596 Other disorders of bladder Genitourinary 0.965 0.887 – 1.05 0.402 673 5962 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.09 0.853 – 1.39 0.497 75 680 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 0.981 0.879 – 1.1 0.735 381 3817 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.03 0.909 – 1.18 0.609 278 2509 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.946 0.784 – 1.14 0.559 129 1171 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.04 0.902 – 1.21 0.565 217 2148 exclusion phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.21 0.883 – 1.66 0.235 40 454 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.37 0.898 – 2.1 0.144 25 281 exclusion phecode
598.4 Other cells and casts in urine Genitourinary 1.25 0.806 – 1.95 0.316 23 247 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.982 0.938 – 1.03 0.425 3011 7568 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.821 0.677 – 0.996 0.045 132 1245 exclusion phecode
599.2 Retention of urine Genitourinary 1.01 0.942 – 1.08 0.776 1038 6664 exclusion phecode
599.3 Dysuria Genitourinary 0.979 0.914 – 1.05 0.543 1049 6736 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.966 0.898 – 1.04 0.345 972 6365 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 0.986 0.922 – 1.05 0.68 1105 6871 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.27 1.06 – 1.52 0.01 142 1204 exclusion phecode
599.7 Urethral discharge Genitourinary 0.922 0.583 – 1.46 0.728 18 194 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 0.93 0.869 – 0.996 0.0373 1114 6590 exclusion phecode
599.9 Other abnormality of urination Genitourinary 0.902 0.826 – 0.984 0.0201 621 5727 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.884 0.798 – 0.978 0.0173 641 1750 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 0.903 0.764 – 1.07 0.23 157 1631 exclusion phecode
601.1 Prostatitis Genitourinary 0.863 0.672 – 1.11 0.249 76 724 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.865 0.572 – 1.31 0.491 31 199 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1.46 0.766 – 2.8 0.248 12 142 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.863 0.671 – 1.11 0.249 61 681 exclusion phecode
601.4 Balanoposthitis Genitourinary 1.19 0.691 – 2.06 0.525 13 226 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.13 0.761 – 1.68 0.542 23 286 exclusion phecode
602 Other disorders of prostate Genitourinary 1.1 0.838 – 1.45 0.482 67 483 exclusion phecode
602.3 Dysplasia of prostate Genitourinary 1.26 0.651 – 2.42 0.497 15 93 exclusion phecode
603 Other disorders of testis Genitourinary 0.998 0.804 – 1.24 0.984 86 836 exclusion phecode
603.1 Hydrocele Genitourinary 0.959 0.717 – 1.28 0.779 47 521 exclusion phecode
603.2 Spermatocele Genitourinary 0.966 0.712 – 1.31 0.826 40 283 exclusion phecode
604 Disorders of penis Genitourinary 0.956 0.798 – 1.14 0.62 133 1209 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.26 0.783 – 2.02 0.343 16 263 exclusion phecode
604.3 Peyronie's disease Genitourinary 0.935 0.687 – 1.27 0.666 48 330 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.888 0.801 – 0.983 0.0224 496 2198 exclusion phecode
608 Other disorders of male genital organs Genitourinary 0.948 0.843 – 1.07 0.373 317 2629 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.933 0.747 – 1.17 0.54 77 860 exclusion phecode
609.1 Infertility, male Genitourinary 0.983 0.763 – 1.27 0.892 56 653 exclusion phecode
609.11 Azoospermia and oligospermia Genitourinary 1.38 0.855 – 2.23 0.187 14 230 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.705 0.466 – 1.07 0.0978 24 295 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.898 0.837 – 0.964 0.00305 1103 4593 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.931 0.843 – 1.03 0.162 506 3675 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 0.66 0.388 – 1.12 0.126 19 147 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.888 0.822 – 0.96 0.00274 879 4543 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.957 0.855 – 1.07 0.439 390 3126 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.897 0.846 – 0.951 0.00029 1789 4939 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.872 0.817 – 0.929 2.65e-05 1489 4263 exclusion phecode
611.11 Mammographic microcalcification Genitourinary 0.844 0.751 – 0.949 0.00462 364 2535 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.907 0.846 – 0.973 0.00654 1089 4931 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.879 0.761 – 1.02 0.0802 232 2773 exclusion phecode
612.1 Galactorrhea Genitourinary 0.887 0.615 – 1.28 0.519 34 435 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.969 0.807 – 1.16 0.739 135 2033 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 0.464 0.301 – 0.715 0.000497 36 230 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.937 0.875 – 1 0.0603 1132 5978 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 0.909 0.767 – 1.08 0.271 152 1564 exclusion phecode
613.5 Mastodynia Genitourinary 1.04 0.945 – 1.15 0.397 489 4210 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.851 0.744 – 0.974 0.019 269 2329 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 0.873 0.764 – 0.998 0.0469 273 2469 exclusion phecode
613.9 Breast disorder NOS Genitourinary 0.933 0.838 – 1.04 0.206 424 3595 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.975 0.909 – 1.04 0.468 1089 5485 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.08 0.852 – 1.38 0.509 84 897 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1 0.832 – 1.2 0.996 140 1356 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.02 0.668 – 1.57 0.914 31 282 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.942 0.712 – 1.25 0.679 61 500 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.973 0.755 – 1.25 0.835 72 687 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.979 0.72 – 1.33 0.891 52 476 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.954 0.886 – 1.03 0.219 944 5450 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.998 0.767 – 1.3 0.988 71 767 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.957 0.885 – 1.04 0.279 820 5315 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.18 0.821 – 1.7 0.369 37 368 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.77 0.575 – 1.03 0.0795 59 631 exclusion phecode
615 Endometriosis Genitourinary 0.996 0.896 – 1.11 0.939 433 3999 exclusion phecode
618 Genital prolapse Genitourinary 0.947 0.859 – 1.04 0.274 508 4723 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.93 0.827 – 1.05 0.224 345 3445 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.986 0.825 – 1.18 0.876 145 1379 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.974 0.755 – 1.26 0.84 73 757 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1 0.811 – 1.24 0.986 103 1118 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 0.995 0.938 – 1.06 0.865 1658 5216 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.918 0.816 – 1.03 0.16 344 3480 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 0.972 0.818 – 1.15 0.745 154 1622 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.933 0.785 – 1.11 0.435 163 1311 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.981 0.903 – 1.07 0.645 760 5121 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.06 0.939 – 1.2 0.34 326 3206 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1.1 0.903 – 1.34 0.342 118 1063 exclusion phecode
620.1 Dysplasia of cervix Genitourinary 0.959 0.726 – 1.27 0.765 57 513 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.773 0.595 – 1 0.0536 63 1163 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.889 0.792 – 0.998 0.0469 353 3805 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.871 0.762 – 0.997 0.0444 258 2965 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 0.91 0.748 – 1.11 0.348 123 1162 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.04 0.898 – 1.21 0.596 220 2246 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 1.01 0.907 – 1.12 0.884 437 3600 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 1.01 0.76 – 1.33 0.96 55 525 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 1.21 0.775 – 1.89 0.403 28 159 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.942 0.843 – 1.05 0.286 388 3990 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.955 0.899 – 1.01 0.131 1668 4852 exclusion phecode
625.1 Dyspareunia Genitourinary 0.935 0.837 – 1.04 0.23 405 3480 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.937 0.881 – 0.996 0.0364 1676 4395 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.927 0.865 – 0.994 0.0324 1227 4097 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 1.04 0.914 – 1.18 0.559 304 2629 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 0.955 0.867 – 1.05 0.347 547 3486 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.92 0.835 – 1.01 0.0912 552 3582 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.906 0.794 – 1.03 0.143 278 2647 exclusion phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.852 0.694 – 1.05 0.126 108 1134 exclusion phecode
626.2 Dysmenorrhea Genitourinary 1 0.898 – 1.12 0.959 408 3005 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.886 0.708 – 1.11 0.288 99 955 exclusion phecode
626.8 Infertility, female Genitourinary 0.904 0.79 – 1.04 0.146 255 2068 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.9 0.839 – 0.964 0.0027 1243 3886 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 0.839 0.735 – 0.959 0.00982 277 2549 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.895 0.825 – 0.97 0.00729 834 3588 exclusion phecode
627.21 Symptomatic artificial menopause Genitourinary 0.802 0.557 – 1.15 0.236 40 402 exclusion phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.784 0.634 – 0.971 0.0258 113 855 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.868 0.764 – 0.986 0.0293 314 2315 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 0.983 0.782 – 1.24 0.886 91 963 exclusion phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.972 0.791 – 1.19 0.784 118 838 exclusion phecode
628 Ovarian cyst Genitourinary 0.923 0.838 – 1.02 0.103 539 3925 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.07 0.929 – 1.23 0.351 244 2293 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.924 0.728 – 1.17 0.515 90 772 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.795 0.55 – 1.15 0.225 30 347 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.867 0.735 – 1.02 0.0876 183 1632 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.874 0.715 – 1.07 0.19 122 1112 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.85 0.671 – 1.08 0.177 88 909 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.954 0.847 – 1.07 0.435 351 2386 exclusion phecode
636.1 Threatened premature labor Pregnancy Complications 1.06 0.873 – 1.29 0.56 131 1173 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 1 0.79 – 1.27 0.981 92 869 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.909 0.753 – 1.1 0.317 132 1359 exclusion phecode
636.8 Cervical incompetence Pregnancy Complications 1.39 0.888 – 2.18 0.149 22 245 exclusion phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.22 0.786 – 1.9 0.372 20 240 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.844 0.698 – 1.02 0.0813 129 1768 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.876 0.668 – 1.15 0.341 66 885 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.965 0.747 – 1.25 0.783 71 800 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.784 0.545 – 1.13 0.192 35 368 exclusion phecode
644 Anemia during pregnancy Pregnancy Complications 1.01 0.773 – 1.31 0.955 69 747 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.959 0.828 – 1.11 0.578 227 2138 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.14 0.887 – 1.48 0.301 75 655 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.955 0.719 – 1.27 0.752 63 712 exclusion phecode
647.3 Major puerperal infection Pregnancy Complications 0.92 0.567 – 1.49 0.736 20 204 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.97 0.862 – 1.09 0.615 367 2532 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.863 0.708 – 1.05 0.143 124 1610 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.01 0.845 – 1.2 0.951 163 1713 exclusion phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.907 0.677 – 1.21 0.512 54 637 exclusion phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 0.796 0.61 – 1.04 0.094 65 637 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.925 0.837 – 1.02 0.126 514 3055 exclusion phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 0.904 0.768 – 1.06 0.226 188 1757 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.939 0.818 – 1.08 0.376 253 2170 exclusion phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 1.01 0.499 – 2.06 0.969 5 144 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.929 0.81 – 1.07 0.291 266 2143 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.15 0.874 – 1.52 0.313 64 707 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.881 0.634 – 1.22 0.452 44 543 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.713 0.543 – 0.937 0.0153 63 580 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.16 1.1 – 1.24 7.58e-07 1331 9223 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.07 0.936 – 1.22 0.327 259 2612 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.31 1.13 – 1.52 0.000277 224 2219 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.21 1.08 – 1.35 0.000648 397 4472 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.16 1.04 – 1.29 0.00617 406 4641 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.21 1.07 – 1.36 0.00191 330 3685 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.17 1.03 – 1.32 0.0183 285 3560 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.08 0.98 – 1.19 0.121 485 4893 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.02 0.841 – 1.24 0.819 114 1391 exclusion phecode
686.2 Impetigo Dermatologic 1.14 0.915 – 1.42 0.243 102 1017 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.23 0.848 – 1.78 0.275 28 403 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.06 0.744 – 1.52 0.734 34 380 exclusion phecode
686.5 Pyoderma Dermatologic 2.13 1.02 – 4.45 0.0438 8 144 exclusion phecode
687 Symptoms affecting skin Dermatologic 1.01 0.906 – 1.12 0.912 449 3752 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.988 0.934 – 1.05 0.682 1623 8190 exclusion phecode
687.3 Changes in skin texture Dermatologic 1.09 0.857 – 1.38 0.49 85 837 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.04 0.982 – 1.11 0.171 1359 8010 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.922 0.877 – 0.969 0.00136 2241 8716 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.903 0.846 – 0.964 0.00239 1200 6764 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.903 0.845 – 0.964 0.00232 1200 6752 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.959 0.794 – 1.16 0.661 123 1322 exclusion phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 1.43 0.887 – 2.3 0.142 21 163 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.853 0.774 – 0.94 0.00131 500 4084 exclusion phecode
694.1 Vitiligo Dermatologic 1.14 0.793 – 1.64 0.48 37 300 exclusion phecode
694.2 Other dyschromia Dermatologic 0.837 0.755 – 0.927 0.000683 447 3711 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.08 0.666 – 1.74 0.767 24 163 exclusion phecode
695 Erythematous conditions Dermatologic 0.964 0.894 – 1.04 0.344 844 6904 exclusion phecode
695.1 Toxic erythema Dermatologic 1.1 0.623 – 1.94 0.742 15 173 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.17 0.689 – 1.97 0.567 20 172 exclusion phecode
695.3 Rosacea Dermatologic 0.804 0.719 – 0.9 0.000138 366 3953 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.11 0.944 – 1.31 0.204 185 1711 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.12 0.859 – 1.46 0.4 67 616 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.09 0.925 – 1.29 0.297 177 1613 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 1.04 0.856 – 1.27 0.678 113 1324 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1 0.818 – 1.22 0.996 105 1866 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.866 0.515 – 1.46 0.588 15 165 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.09 0.907 – 1.31 0.357 132 1504 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.973 0.856 – 1.11 0.67 275 3123 exclusion phecode
696.3 Pityriasis Dermatologic 0.711 0.49 – 1.03 0.0726 36 277 exclusion phecode
696.4 Psoriasis Dermatologic 1.02 0.893 – 1.18 0.731 238 2876 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 1.01 0.874 – 1.16 0.913 222 2603 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.88 0.636 – 1.22 0.44 41 615 exclusion phecode
697 Sarcoidosis Dermatologic 1.18 0.869 – 1.59 0.294 47 653 exclusion phecode
698 Pruritus and related conditions Dermatologic 0.984 0.897 – 1.08 0.725 557 5421 exclusion phecode
700 Corns and callosities Dermatologic 0.951 0.824 – 1.1 0.488 229 2355 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.958 0.907 – 1.01 0.121 1735 9024 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.959 0.798 – 1.15 0.655 141 1181 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.997 0.914 – 1.09 0.95 623 5144 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.965 0.797 – 1.17 0.713 133 1404 exclusion phecode
701.4 Keloid scar Dermatologic 0.934 0.786 – 1.11 0.44 158 1531 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1.13 0.901 – 1.41 0.294 91 904 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.87 0.82 – 0.924 6.14e-06 1588 6196 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.82 0.761 – 0.883 1.72e-07 950 5238 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.878 0.823 – 0.937 8.38e-05 1277 6486 exclusion phecode
702.4 Degenerative skin disorders Dermatologic 1.19 0.743 – 1.91 0.466 25 197 exclusion phecode
703 Diseases of nail, NOS Dermatologic 0.958 0.851 – 1.08 0.474 333 3307 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.979 0.83 – 1.15 0.797 167 1978 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.966 0.894 – 1.05 0.392 765 7325 exclusion phecode
704.1 Alopecia Dermatologic 0.896 0.804 – 0.998 0.0468 409 3630 exclusion phecode
704.11 Alopecia Areata Dermatologic 1.22 0.747 – 2 0.425 21 179 exclusion phecode
704.12 Telogen effluvium Dermatologic 0.792 0.477 – 1.31 0.366 22 160 exclusion phecode
704.2 Hirsutism Dermatologic 1.15 0.848 – 1.56 0.369 45 882 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.04 0.932 – 1.16 0.469 375 3901 exclusion phecode
705 Disorders of sweat glands Dermatologic 0.969 0.798 – 1.18 0.749 115 1541 exclusion phecode
705.1 Dyshidrosis Dermatologic 0.845 0.571 – 1.25 0.399 33 340 exclusion phecode
705.3 Hidradenitis Dermatologic 1.11 0.788 – 1.55 0.559 33 639 exclusion phecode
705.8 Hyperhidrosis Dermatologic 0.963 0.843 – 1.1 0.579 263 2649 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 0.9 0.85 – 0.953 0.000309 1531 9248 exclusion phecode
706.1 Acne Dermatologic 0.859 0.796 – 0.927 9.7e-05 832 5978 exclusion phecode
706.2 Sebaceous cyst Dermatologic 0.932 0.856 – 1.01 0.105 644 6019 exclusion phecode
706.3 Seborrhea Dermatologic 0.563 0.328 – 0.966 0.037 16 137 exclusion phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.934 0.827 – 1.05 0.27 322 3244 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.17 1.07 – 1.28 0.000571 597 5738 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.25 1.08 – 1.45 0.00367 206 1652 exclusion phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.22 1.04 – 1.43 0.0156 180 1928 exclusion phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1.13 1.01 – 1.27 0.0334 356 3547 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 1 0.898 – 1.12 0.963 383 3529 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.02 0.849 – 1.22 0.848 132 1192 exclusion phecode
709.3 Systemic sclerosis Dermatologic 0.967 0.76 – 1.23 0.784 72 515 exclusion phecode
709.5 Dermatomyositis Dermatologic 0.798 0.517 – 1.23 0.309 18 210 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.18 0.793 – 1.76 0.412 27 213 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.03 0.896 – 1.19 0.672 239 2277 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.27 1.12 – 1.45 0.000206 282 2616 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.28 1.12 – 1.45 0.000222 275 2462 exclusion phecode
710.11 Acute osteomyelitis Musculoskeletal 1.34 1.11 – 1.62 0.00239 130 1196 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.22 1 – 1.48 0.0477 126 1049 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.31 1.15 – 1.5 7.02e-05 258 2362 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 0.826 0.647 – 1.06 0.126 77 883 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.01 0.74 – 1.38 0.947 46 610 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.07 0.748 – 1.54 0.704 31 400 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.09 0.841 – 1.42 0.503 62 642 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.36 0.846 – 2.19 0.204 20 304 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.14 1.03 – 1.26 0.0113 468 4438 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.21 1.08 – 1.35 0.00114 386 3663 exclusion phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 0.988 0.69 – 1.41 0.946 33 237 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.08 0.942 – 1.24 0.268 244 2802 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.17 0.877 – 1.55 0.291 57 676 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.988 0.739 – 1.32 0.937 50 545 exclusion phecode
716 Other arthropathies Musculoskeletal 1.06 1.01 – 1.12 0.0159 2506 7939 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.815 0.562 – 1.18 0.281 33 432 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.743 0.48 – 1.15 0.185 20 272 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.06 1.01 – 1.12 0.014 2492 7936 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.01 0.753 – 1.37 0.926 52 562 exclusion phecode
720 Spinal stenosis Musculoskeletal 1.08 0.989 – 1.17 0.0882 649 6151 exclusion phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1.09 0.985 – 1.21 0.0947 428 4881 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1.09 1.02 – 1.17 0.0125 1075 7226 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.1 1.02 – 1.18 0.00866 1008 7068 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.14 0.959 – 1.36 0.137 152 1737 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 1.02 0.727 – 1.42 0.927 40 562 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.1 1.03 – 1.18 0.0028 1199 8037 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.12 1.03 – 1.22 0.00798 659 7186 exclusion phecode
722.3 Schmorl's nodes Musculoskeletal 1.01 0.692 – 1.47 0.966 32 264 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.11 1.03 – 1.2 0.0101 752 6798 exclusion phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.18 0.94 – 1.48 0.155 92 1084 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.14 0.888 – 1.46 0.305 73 827 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.01 0.9 – 1.13 0.904 370 4256 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.04 0.906 – 1.2 0.548 230 2233 exclusion phecode
723.1 Torticollis Musculoskeletal 1.14 0.864 – 1.5 0.36 62 589 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.03 0.953 – 1.1 0.507 890 7601 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1.01 0.918 – 1.11 0.844 520 5376 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.923 0.746 – 1.14 0.457 98 1021 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.13 0.966 – 1.33 0.124 175 2182 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.08 0.95 – 1.22 0.248 288 3198 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.95 0.902 – 1 0.0498 2111 7342 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.953 0.9 – 1.01 0.103 1605 7313 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.932 0.792 – 1.1 0.394 173 2098 exclusion phecode
726.3 Bursitis Musculoskeletal 0.839 0.748 – 0.942 0.00285 359 3818 exclusion phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.921 0.801 – 1.06 0.251 228 2653 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.974 0.919 – 1.03 0.365 1618 7309 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.994 0.913 – 1.08 0.88 681 6062 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.906 0.708 – 1.16 0.433 80 907 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.973 0.866 – 1.09 0.645 347 3217 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 1 0.797 – 1.26 0.993 89 1092 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.931 0.839 – 1.03 0.177 420 4585 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.05 0.892 – 1.24 0.541 167 1482 exclusion phecode
727.8 Plica syndrome Musculoskeletal 0.841 0.622 – 1.14 0.261 50 385 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.973 0.907 – 1.04 0.448 988 7020 exclusion phecode
728.1 Muscular calcification and ossification Musculoskeletal 1.41 0.904 – 2.19 0.13 22 186 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.05 0.83 – 1.33 0.689 77 712 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.871 0.79 – 0.961 0.00583 473 5331 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.688 0.555 – 0.852 0.000611 108 781 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.15 1.06 – 1.25 0.00133 669 6222 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.44 0.907 – 2.28 0.122 19 168 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.932 0.512 – 1.7 0.819 9 304 exclusion phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 1.04 0.66 – 1.64 0.861 21 155 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.33 0.923 – 1.91 0.126 36 353 exclusion phecode
732 Osteochondropathies Musculoskeletal 1.02 0.813 – 1.27 0.887 91 1000 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1 0.716 – 1.41 0.978 40 530 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.03 0.656 – 1.61 0.901 24 265 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.963 0.902 – 1.03 0.265 1259 6039 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.16 0.862 – 1.56 0.325 53 452 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.18 0.992 – 1.4 0.0609 160 1061 exclusion phecode
733.6 Costochondritis Musculoskeletal 1.1 0.862 – 1.4 0.449 79 878 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.31 1.13 – 1.52 0.000392 207 1900 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.28 0.876 – 1.86 0.204 33 261 exclusion phecode
735 Acquired foot deformities Musculoskeletal 0.94 0.869 – 1.02 0.127 762 6663 exclusion phecode
735.1 Flat foot Musculoskeletal 0.848 0.694 – 1.04 0.107 109 1399 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 0.956 0.838 – 1.09 0.501 279 2535 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.05 0.881 – 1.25 0.592 160 1562 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.984 0.789 – 1.23 0.883 103 848 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.848 0.754 – 0.953 0.00573 348 3312 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 0.928 0.85 – 1.01 0.0972 614 6048 exclusion phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.966 0.664 – 1.41 0.858 32 220 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.11 0.842 – 1.47 0.455 66 463 exclusion phecode
736.3 Acquired deformities of hip Musculoskeletal 0.932 0.538 – 1.61 0.802 16 188 exclusion phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 1.17 0.864 – 1.57 0.316 48 682 exclusion phecode
736.5 Acquired deformities of knee Musculoskeletal 0.947 0.672 – 1.33 0.754 32 499 exclusion phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.83 0.649 – 1.06 0.137 78 779 exclusion phecode
737 Curvature of spine Musculoskeletal 0.978 0.884 – 1.08 0.672 462 3890 exclusion phecode
737.1 Kyphosis (acquired) Musculoskeletal 1.07 0.87 – 1.32 0.52 110 1080 exclusion phecode
737.2 Lordosis (acquired) Musculoskeletal 2.12 1.12 – 4.02 0.0212 12 152 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.961 0.86 – 1.07 0.476 386 3060 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.16 1.06 – 1.26 0.00106 631 5535 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.22 1.05 – 1.42 0.00991 198 2157 exclusion phecode
739 Contracture of joint Musculoskeletal 1.05 0.882 – 1.25 0.59 160 1370 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.05 1 – 1.1 0.0374 2937 7929 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.992 0.926 – 1.06 0.813 1157 6673 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.986 0.917 – 1.06 0.699 1023 6187 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.1 0.909 – 1.33 0.327 122 1668 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.03 0.91 – 1.17 0.616 306 2887 exclusion phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 1.17 0.915 – 1.5 0.209 71 857 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.06 1.01 – 1.11 0.0288 2783 7867 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.01 0.958 – 1.06 0.719 1879 8544 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.947 0.717 – 1.25 0.704 54 599 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.01 0.899 – 1.14 0.825 323 2891 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 1.12 1.02 – 1.23 0.0234 496 4936 exclusion phecode
741.4 Joint effusions Musculoskeletal 1 0.916 – 1.1 0.936 540 5845 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 0.831 0.508 – 1.36 0.461 18 199 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 1.26 0.678 – 2.35 0.461 11 169 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.981 0.917 – 1.05 0.581 1043 8142 exclusion phecode
742.1 Loose body in joint Musculoskeletal 0.896 0.62 – 1.3 0.561 28 422 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.915 0.73 – 1.15 0.44 85 933 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.13 0.875 – 1.47 0.34 62 634 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.978 0.912 – 1.05 0.528 985 8034 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.02 0.973 – 1.07 0.382 2537 8248 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.04 0.971 – 1.12 0.248 1230 3995 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.04 0.969 – 1.12 0.273 1217 3952 exclusion phecode
743.12 Senile osteoporosis Musculoskeletal 0.969 0.843 – 1.11 0.655 292 1134 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1.14 0.906 – 1.43 0.264 109 601 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.06 0.941 – 1.2 0.321 326 2028 exclusion phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 1.09 0.904 – 1.32 0.358 131 862 exclusion phecode
743.22 Pathologic fracture of femur Musculoskeletal 1.69 1.19 – 2.41 0.0037 43 267 exclusion phecode
743.4 Stress fracture Musculoskeletal 0.888 0.73 – 1.08 0.236 120 924 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.01 0.958 – 1.07 0.64 1853 7744 exclusion phecode
745 Pain in joint Musculoskeletal 0.979 0.94 – 1.02 0.29 4517 6498 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.991 0.903 – 1.09 0.85 525 4965 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.06 0.951 – 1.18 0.299 389 3920 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1.02 0.869 – 1.2 0.788 170 1512 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.21 1.01 – 1.46 0.0402 128 1550 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.01 0.811 – 1.25 0.947 88 884 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.872 0.73 – 1.04 0.132 140 1163 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.04 0.705 – 1.54 0.84 29 272 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.919 0.786 – 1.07 0.288 206 1544 exclusion phecode
749.1 Cleft palate Congenital Anomalies 0.792 0.568 – 1.1 0.17 43 310 exclusion phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.92 0.66 – 1.28 0.622 46 303 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 1.15 1.01 – 1.32 0.0347 261 2050 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.988 0.791 – 1.24 0.919 88 858 exclusion phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.974 0.656 – 1.45 0.897 29 248 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.987 0.648 – 1.5 0.95 24 258 exclusion phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 1.03 0.739 – 1.42 0.882 39 269 exclusion phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 1 0.513 – 1.96 0.997 11 122 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.17 0.989 – 1.37 0.0667 176 1251 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.21 0.985 – 1.48 0.0697 110 720 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.09 0.833 – 1.43 0.526 69 509 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.04 0.948 – 1.15 0.392 518 4659 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.02 0.863 – 1.21 0.793 161 1548 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.12 0.914 – 1.38 0.267 116 1100 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.834 0.594 – 1.17 0.294 38 353 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.01 0.894 – 1.13 0.918 332 3026 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 1.06 0.923 – 1.22 0.394 227 2060 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.89 0.692 – 1.14 0.365 74 675 exclusion phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.3 0.98 – 1.74 0.0687 62 532 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.06 0.922 – 1.23 0.395 227 2647 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.11 0.949 – 1.31 0.189 177 2072 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.832 0.604 – 1.14 0.258 42 500 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.919 0.692 – 1.22 0.56 58 599 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.18 0.866 – 1.6 0.298 52 476 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1 0.57 – 1.75 0.999 14 150 exclusion phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 0.854 0.483 – 1.51 0.586 14 144 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.13 0.988 – 1.3 0.075 247 2582 exclusion phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 0.932 0.617 – 1.41 0.736 27 305 exclusion phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 1.08 0.883 – 1.33 0.444 109 1222 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.07 0.91 – 1.26 0.416 175 1999 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.905 0.713 – 1.15 0.415 78 912 exclusion phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 1.31 0.795 – 2.15 0.292 18 180 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.13 0.892 – 1.42 0.32 84 961 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.13 0.837 – 1.52 0.427 50 565 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.03 0.922 – 1.16 0.57 354 3352 exclusion phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.644 0.385 – 1.08 0.0932 21 172 exclusion phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 1.06 0.766 – 1.47 0.715 49 237 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.955 0.737 – 1.24 0.729 62 840 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.06 0.919 – 1.21 0.437 229 2290 exclusion phecode
757 Congenital anomalies of the integument Congenital Anomalies 0.82 0.66 – 1.02 0.0712 103 926 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.02 0.771 – 1.35 0.888 58 491 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.95 0.674 – 1.34 0.767 38 363 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.926 0.784 – 1.09 0.363 160 1493 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.803 0.477 – 1.35 0.407 14 188 exclusion phecode
760 Back pain Symptoms 1.09 1.05 – 1.14 3.72e-05 3440 7569 exclusion phecode
761 Cervicalgia Symptoms 1.08 1.02 – 1.14 0.0082 1576 9228 exclusion phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 1.05 0.966 – 1.14 0.247 662 7263 exclusion phecode
764 Sciatica Symptoms 1.09 0.999 – 1.19 0.0519 611 7266 exclusion phecode
765 Cervical radiculitis Symptoms 1.11 0.992 – 1.24 0.0679 371 3862 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.08 1.01 – 1.16 0.0209 1017 8661 exclusion phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.22 0.805 – 1.84 0.349 28 264 exclusion phecode
769 Nonallopathic lesions NEC Symptoms 1.04 0.909 – 1.18 0.588 292 2634 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.04 0.975 – 1.11 0.241 1254 8242 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.09 1.02 – 1.17 0.00964 1015 8355 exclusion phecode
771.1 Swelling of limb Symptoms 1.13 1.05 – 1.21 0.000502 1061 8316 exclusion phecode
771.2 Cramp of limb Symptoms 1.01 0.877 – 1.16 0.904 233 2375 exclusion phecode
772 Symptoms of the muscles Symptoms 0.969 0.881 – 1.07 0.523 507 4726 exclusion phecode
772.1 Muscular wasting and disuse atrophy Symptoms 1.13 0.929 – 1.36 0.226 123 1091 exclusion phecode
772.2 Spasm of muscle Symptoms 0.969 0.883 – 1.06 0.505 542 5508 exclusion phecode
772.3 Muscle weakness Symptoms 1.05 0.968 – 1.15 0.226 640 6137 exclusion phecode
772.4 Rhabdomyolysis Symptoms 1.11 0.774 – 1.6 0.564 38 338 exclusion phecode
772.6 Facial weakness Symptoms 0.974 0.781 – 1.21 0.815 96 1027 exclusion phecode
780 Hypothermia/Chills Symptoms 1.17 0.952 – 1.44 0.135 104 987 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.01 0.921 – 1.1 0.868 574 5709 exclusion phecode
781.1 Loss of height Symptoms 1.21 0.825 – 1.76 0.334 35 214 exclusion phecode
781.2 Abnormal posture Symptoms 0.868 0.493 – 1.53 0.624 14 123 exclusion phecode
782.3 Edema Symptoms 1.21 1.12 – 1.29 1.86e-07 976 8470 exclusion phecode
782.6 Pallor and flushing Symptoms 0.918 0.798 – 1.06 0.231 245 2410 exclusion phecode
783 Fever of unknown origin Symptoms 1.15 1.08 – 1.22 8.88e-06 1350 9562 exclusion phecode
783.1 Postprocedural fever Symptoms 1.22 0.925 – 1.62 0.157 58 642 exclusion phecode
785 Abdominal pain Symptoms 1.07 1.03 – 1.11 0.00167 3950 7061 exclusion phecode
788 Syncope and collapse Symptoms 1.05 0.98 – 1.13 0.157 887 8223 exclusion phecode
789 Nausea and vomiting Symptoms 1.11 1.06 – 1.16 1.21e-05 2685 8302 exclusion phecode
789.1 Persistent vomiting Symptoms 1.3 1.12 – 1.51 0.000544 203 1910 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.1 1 – 1.22 0.0442 499 4987 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.15 0.837 – 1.58 0.388 42 564 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.08 1.02 – 1.15 0.00771 1441 9098 exclusion phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 0.997 0.736 – 1.35 0.985 46 771 exclusion phecode
790.9 Abnormal arterial blood gases Symptoms 1.36 0.923 – 2.01 0.12 27 339 exclusion phecode
791 Gangrene Symptoms 1.21 0.959 – 1.53 0.108 77 589 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 1 0.929 – 1.08 0.941 885 4183 exclusion phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 1.05 0.936 – 1.18 0.404 370 2793 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.04 0.841 – 1.29 0.708 96 1118 exclusion phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 1.03 0.947 – 1.13 0.454 639 5303 exclusion phecode
795.8 Abnormal tumor markers Symptoms 0.916 0.808 – 1.04 0.165 295 2567 exclusion phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 0.91 0.503 – 1.64 0.755 11 129 exclusion phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 1.01 0.764 – 1.34 0.928 59 490 exclusion phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.795 0.695 – 0.908 0.000758 314 1514 exclusion phecode
797 Shock Symptoms 1.23 1.01 – 1.5 0.0386 129 1151 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.19 0.862 – 1.63 0.293 54 436 exclusion phecode
798 Malaise and fatigue Symptoms 1.09 1.04 – 1.14 0.000535 2655 8349 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1.06 0.95 – 1.18 0.295 383 4177 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.09 0.999 – 1.19 0.0529 595 5364 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.24 1.03 – 1.48 0.0209 151 1086 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.16 0.993 – 1.36 0.0614 192 1460 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.19 1.03 – 1.37 0.0202 221 2131 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.891 0.722 – 1.1 0.279 105 871 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.03 0.939 – 1.13 0.526 536 5414 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.08 0.942 – 1.23 0.274 249 2719 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.04 0.853 – 1.27 0.699 123 885 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 1 0.918 – 1.09 0.967 608 4860 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1.16 0.989 – 1.37 0.068 177 1770 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.988 0.88 – 1.11 0.832 360 2789 exclusion phecode
803.21 Colles' fracture Injuries & Poisonings 0.956 0.759 – 1.2 0.702 93 688 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.969 0.829 – 1.13 0.697 176 1228 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.988 0.896 – 1.09 0.812 491 3985 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.08 0.964 – 1.21 0.182 347 2856 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.07 0.909 – 1.25 0.433 177 1371 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.03 0.954 – 1.11 0.458 829 6736 exclusion phecode
816 Cerebral laceration and contusion Injuries & Poisonings 1.63 0.933 – 2.84 0.0861 16 101 exclusion phecode
817 Concussion Injuries & Poisonings 1.06 0.926 – 1.21 0.411 258 2679 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.14 0.907 – 1.44 0.257 85 688 exclusion phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 1.34 0.827 – 2.17 0.235 24 189 exclusion phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.03 0.634 – 1.66 0.916 24 203 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.06 0.976 – 1.16 0.157 607 5516 exclusion phecode
830 Dislocation Injuries & Poisonings 0.932 0.866 – 1 0.0594 868 8371 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.896 0.811 – 0.99 0.0304 465 5322 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.975 0.769 – 1.24 0.834 80 1028 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.949 0.9 – 1 0.0557 1782 9030 exclusion phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.994 0.785 – 1.26 0.96 82 1115 exclusion phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.942 0.822 – 1.08 0.392 253 3256 exclusion phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.914 0.843 – 0.99 0.0267 746 6296 exclusion phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.931 0.827 – 1.05 0.239 339 3848 exclusion phecode
842 Other sprains and strains Injuries & Poisonings 1.01 0.897 – 1.13 0.902 334 3490 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.14 1.03 – 1.26 0.00997 461 4470 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.26 1.16 – 1.37 3.82e-08 669 5863 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.36 1.11 – 1.66 0.00321 107 959 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.22 1.09 – 1.35 0.000264 412 4147 exclusion phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 0.993 0.749 – 1.32 0.962 54 619 exclusion phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.2 0.897 – 1.59 0.223 59 578 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.13 0.991 – 1.29 0.0676 269 3092 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.14 1.04 – 1.25 0.00744 517 5130 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.23 1.12 – 1.35 9.16e-06 567 4779 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.45 1.03 – 2.04 0.0352 40 366 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.08 1 – 1.15 0.0381 997 8403 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.41 1.05 – 1.89 0.0214 55 444 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 0.843 0.61 – 1.17 0.302 41 324 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1 0.898 – 1.12 0.964 392 3010 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.05 0.795 – 1.38 0.747 60 476 exclusion phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 1.11 0.885 – 1.4 0.357 93 604 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.934 0.716 – 1.22 0.611 64 395 exclusion phecode
870.8 Open wound of genital organs Injuries & Poisonings 1 0.705 – 1.43 0.988 38 391 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.08 1 – 1.17 0.0425 808 7420 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.04 0.865 – 1.25 0.669 128 1282 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.954 0.83 – 1.1 0.512 233 2284 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.44 1.14 – 1.81 0.00213 85 951 exclusion phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.19 0.857 – 1.66 0.296 44 583 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.27 1.04 – 1.55 0.0182 109 1075 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.3 0.927 – 1.83 0.128 34 304 exclusion phecode
875 Non-healing surgical wound Injuries & Poisonings 1.09 0.902 – 1.31 0.385 127 1275 exclusion phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.06 0.896 – 1.26 0.483 148 1736 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.12 0.973 – 1.28 0.116 237 2291 exclusion phecode
910 Superficial injury, infected Injuries & Poisonings 0.819 0.514 – 1.31 0.402 22 268 exclusion phecode
911 Blister Injuries & Poisonings 1.11 0.82 – 1.5 0.5 50 571 exclusion phecode
912 Insect bite Injuries & Poisonings 1.02 0.832 – 1.24 0.867 112 1187 exclusion phecode
913 Toxic effect of venom Injuries & Poisonings 0.806 0.646 – 1.01 0.0565 85 744 exclusion phecode
916 Contusion Injuries & Poisonings 1.06 0.994 – 1.14 0.0756 987 8993 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 1.03 0.881 – 1.21 0.698 184 2047 exclusion phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.931 0.775 – 1.12 0.442 149 1629 exclusion phecode
938 Dermatitis due to solar radiation Dermatologic 0.896 0.841 – 0.955 0.00072 1328 6321 exclusion phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.9 0.664 – 1.22 0.498 48 508 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.89 0.834 – 0.949 0.000402 1269 6176 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.01 0.951 – 1.07 0.778 1492 7699 exclusion phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 1.24 0.799 – 1.94 0.334 28 224 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.06 0.741 – 1.52 0.748 37 380 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.39 1.07 – 1.8 0.0137 76 617 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.944 0.78 – 1.14 0.552 125 1147 exclusion phecode
947 Urticaria Dermatologic 1.04 0.914 – 1.17 0.582 287 2944 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.05 0.996 – 1.12 0.0672 1617 7675 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.09 0.896 – 1.34 0.376 107 1049 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.709 0.485 – 1.04 0.0772 34 324 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.08 0.953 – 1.22 0.237 305 2721 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 0.947 0.662 – 1.35 0.764 38 329 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.11 0.759 – 1.62 0.59 34 249 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.23 1.12 – 1.35 1.47e-05 552 5167 exclusion phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 1.19 0.941 – 1.51 0.144 88 767 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.24 1.1 – 1.39 0.000314 342 3712 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.34 1.11 – 1.61 0.0025 138 1185 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.25 1.09 – 1.44 0.00199 233 2385 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.2 1.02 – 1.41 0.0321 172 1659 exclusion phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.26 0.999 – 1.58 0.0509 84 794 exclusion phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 2.08 1.03 – 4.2 0.0423 11 118 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.13 0.91 – 1.41 0.264 99 974 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.16 1.06 – 1.26 0.000727 662 5444 exclusion phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.17 1.07 – 1.27 0.000463 644 5337 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.2 0.99 – 1.46 0.0627 129 1472 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.19 0.975 – 1.46 0.0872 120 1391 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.18 1.02 – 1.38 0.0307 199 2115 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.34 1.19 – 1.52 2.11e-06 303 3397 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.03 0.686 – 1.54 0.889 27 247 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.29 0.831 – 2.01 0.255 28 229 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.07 0.942 – 1.21 0.306 305 2905 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.4 1.09 – 1.79 0.00783 74 697 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.46 0.861 – 2.46 0.161 18 124 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.48 1.09 – 2 0.0109 51 576 exclusion phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 1.24 0.749 – 2.05 0.404 13 157 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 2.03 1.19 – 3.48 0.00994 16 198 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.53 0.961 – 2.45 0.0728 21 234 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.786 0.456 – 1.35 0.385 14 199 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.813 0.454 – 1.45 0.485 15 160 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.17 1.05 – 1.31 0.00505 383 3849 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.18 1.09 – 1.28 2.43e-05 797 7171 exclusion phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 1 0.884 – 1.13 0.989 288 2809 exclusion phecode
985 Toxic effect of other metals Injuries & Poisonings 1.89 0.982 – 3.65 0.0568 17 92 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.15 0.814 – 1.62 0.431 34 302 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.14 1.06 – 1.22 0.000343 954 6503 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.27 1.14 – 1.4 6.04e-06 461 4485 exclusion phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.15 0.883 – 1.49 0.303 74 650 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.25 1.13 – 1.39 2.89e-05 429 4266 exclusion phecode
994.21 Septic shock Injuries & Poisonings 1.3 1.08 – 1.57 0.00549 138 1270 exclusion phecode
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