Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Body mass index Michigan Genomics Initiative Freeze 3 (MGI) PheWAS analysis

Body mass index — Michigan Genomics Initiative Freeze 3 (MGI) PRS PheWAS

PRS model
PRS ID exprsweb-bmi-21001-raw-plink-mgi-freeze3-20211120Legacy PLINKC+T (GT)UK Biobank GWAS

Evaluation cohort: Michigan Genomics Initiative Freeze 3 (MGI).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: normal-range subset (18.5-24.9).

For this ExPRS, the exclusion sensitivity scan keeps only the study's normal-range subset for Body mass index (18.5-24.9) before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.

688 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.02 0.983 – 1.06 0.271 3004 29292 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.11 1.05 – 1.18 0.000591 1322 13162 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.11 1.04 – 1.19 0.00172 1046 10455 all phecode
008.6 Viral Enteritis Infectious Diseases 1.07 0.986 – 1.15 0.107 770 7676 all phecode
010 Tuberculosis Infectious Diseases 1.05 0.915 – 1.21 0.476 244 2425 all phecode
031 Diseases due to other mycobacteria Infectious Diseases 1.05 0.835 – 1.32 0.684 86 855 all phecode
038 Septicemia Infectious Diseases 1.11 1.07 – 1.16 6.66e-07 2582 24779 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.13 1.03 – 1.24 0.00723 568 5629 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.34 1.16 – 1.54 4.69e-05 235 2350 all phecode
038.3 Bacteremia Infectious Diseases 1.13 1.06 – 1.2 0.000168 1210 12079 all phecode
041 Bacterial infection NOS Infectious Diseases 1.08 1.05 – 1.12 5.02e-08 5750 38799 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.18 1.12 – 1.24 8.47e-10 1707 16977 all phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.22 1.14 – 1.31 2.18e-08 920 9192 all phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.22 1.13 – 1.31 6.41e-07 783 7812 all phecode
041.2 Streptococcus infection Infectious Diseases 1.09 1.03 – 1.15 0.00168 1632 16287 all phecode
041.21 Rheumatic fever / chorea Infectious Diseases 1 0.877 – 1.14 0.994 257 2554 all phecode
041.4 E. coli Infectious Diseases 1.09 1.03 – 1.16 0.0065 1175 11680 all phecode
041.8 H. pylori Infectious Diseases 1.1 0.959 – 1.26 0.178 257 2521 all phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.17 1.05 – 1.3 0.00572 387 3864 all phecode
053 Herpes zoster Infectious Diseases 0.948 0.897 – 1 0.0555 1560 15184 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.958 0.829 – 1.11 0.559 220 2169 all phecode
054 Herpes simplex Infectious Diseases 0.953 0.903 – 1.01 0.0887 1593 15600 all phecode
070 Viral hepatitis Infectious Diseases 1.08 0.999 – 1.16 0.0521 829 8280 all phecode
070.1 Viral hepatitis A Infectious Diseases 1.24 0.976 – 1.58 0.0774 87 860 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.09 0.944 – 1.27 0.231 215 2138 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.08 0.982 – 1.19 0.112 528 5280 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.09 0.934 – 1.27 0.271 197 1964 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.02 0.959 – 1.09 0.492 1145 11381 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.15 0.969 – 1.37 0.109 145 1450 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.14 0.944 – 1.38 0.173 117 1163 all phecode
078 Viral warts & HPV Infectious Diseases 0.909 0.876 – 0.944 5.75e-07 3434 29624 all phecode
079 Viral infection Infectious Diseases 0.95 0.924 – 0.977 0.000293 6664 35342 all phecode
079.1 Varicella infection Infectious Diseases 0.906 0.875 – 0.939 7.34e-08 3793 31251 all phecode
079.2 Infectious mononucleosis Infectious Diseases 0.855 0.753 – 0.972 0.0167 283 2723 all phecode
079.9 Viremia, NOS Infectious Diseases 1.06 0.98 – 1.14 0.153 838 8253 all phecode
080 Postoperative infection Infectious Diseases 1.15 1.11 – 1.2 3.05e-11 2619 26065 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.14 1.08 – 1.2 2.93e-06 1589 15884 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.02 0.949 – 1.09 0.631 965 9630 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.01 0.977 – 1.05 0.471 3544 30054 all phecode
110.1 Dermatophytosis Infectious Diseases 1.02 0.985 – 1.07 0.223 3241 27244 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.03 0.978 – 1.08 0.29 2044 16765 all phecode
110.12 Althete's foot Infectious Diseases 1.06 0.986 – 1.14 0.11 899 8043 all phecode
110.13 Dermatophytosis of the body Infectious Diseases 1.07 0.988 – 1.15 0.0974 790 7827 all phecode
110.2 Dermatomycoses Infectious Diseases 0.939 0.843 – 1.05 0.247 398 3971 all phecode
112 Candidiasis Infectious Diseases 1.09 1.05 – 1.13 5.8e-06 3685 30495 all phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.28 1.18 – 1.39 6.6e-09 682 6732 all phecode
117 Mycoses Infectious Diseases 0.987 0.905 – 1.08 0.776 608 6069 all phecode
117.1 Histoplasmosis Infectious Diseases 1.12 0.882 – 1.42 0.354 81 801 all phecode
117.4 Aspergillosis Infectious Diseases 1.1 0.922 – 1.32 0.281 140 1387 all phecode
130 Spirochetal infection Infectious Diseases 0.889 0.756 – 1.05 0.155 168 1677 all phecode
130.1 Lyme disease Infectious Diseases 0.895 0.734 – 1.09 0.27 116 1160 all phecode
131 Protozoan infection Infectious Diseases 1.48 1.13 – 1.93 0.00424 61 610 all phecode
132 Infestation (lice, mites) Infectious Diseases 1.12 0.961 – 1.3 0.148 195 1948 all phecode
134 Helminthiases Infectious Diseases 0.937 0.742 – 1.18 0.581 83 812 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.07 0.8 – 1.43 0.657 53 513 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.06 1.02 – 1.1 0.00429 3279 32486 all phecode
145 Cancer of mouth Neoplasms 1.03 0.973 – 1.09 0.319 1481 14725 all phecode
145.1 Cancer of lip Neoplasms 1.13 0.879 – 1.45 0.344 76 750 all phecode
145.2 Cancer of tongue Neoplasms 1.02 0.934 – 1.11 0.692 645 6430 all phecode
145.3 Cancer of major salivary glands Neoplasms 0.983 0.877 – 1.1 0.769 361 3597 all phecode
145.4 Cancer of the gums Neoplasms 1.08 0.914 – 1.28 0.357 166 1632 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.13 0.969 – 1.31 0.123 206 2048 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.03 0.966 – 1.09 0.396 1290 12873 all phecode
149.1 Cancer of oropharynx Neoplasms 1.04 0.928 – 1.17 0.497 350 3499 all phecode
149.2 Cancer of nasopharynx Neoplasms 1.08 0.873 – 1.34 0.477 100 1000 all phecode
149.3 Cancer of hypopharynx Neoplasms 0.947 0.739 – 1.21 0.667 82 819 all phecode
149.4 Cancer of larynx Neoplasms 1.15 1.03 – 1.28 0.0156 386 3857 all phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 1.01 0.924 – 1.11 0.78 552 5505 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.943 0.819 – 1.09 0.412 240 2398 all phecode
150 Cancer of esophagus Neoplasms 1.23 1.11 – 1.36 9.03e-05 433 4315 all phecode
151 Cancer of stomach Neoplasms 1.07 0.968 – 1.17 0.193 498 4962 all phecode
153 Colorectal cancer Neoplasms 0.982 0.927 – 1.04 0.528 1458 14383 all phecode
153.2 Colon cancer Neoplasms 0.988 0.926 – 1.05 0.71 1160 11472 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.968 0.897 – 1.05 0.412 815 8093 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.06 0.96 – 1.16 0.26 511 5097 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.08 0.967 – 1.22 0.167 344 3433 all phecode
157 Pancreatic cancer Neoplasms 0.951 0.864 – 1.05 0.308 503 5005 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1 0.949 – 1.06 0.939 1623 15759 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.01 0.955 – 1.06 0.847 1818 17869 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.984 0.85 – 1.14 0.835 221 2206 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.03 0.869 – 1.22 0.752 158 1578 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.998 0.877 – 1.14 0.979 293 2920 all phecode
164 Cancer of intrathoracic organs Neoplasms 0.954 0.795 – 1.15 0.617 133 1324 all phecode
165 Cancer within the respiratory system Neoplasms 1.05 0.993 – 1.12 0.0812 1336 13340 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.04 0.968 – 1.11 0.307 1057 10552 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.976 0.927 – 1.03 0.346 1792 17850 all phecode
170.1 Bone cancer Neoplasms 0.985 0.911 – 1.06 0.697 773 7690 all phecode
170.2 Cancer of connective tissue Neoplasms 0.969 0.912 – 1.03 0.303 1266 12632 all phecode
172 Skin cancer Neoplasms 0.936 0.912 – 0.961 7.41e-07 8608 33186 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.912 0.884 – 0.941 1.16e-08 5330 30106 all phecode
172.11 Melanomas of skin Neoplasms 0.912 0.876 – 0.949 5.35e-06 3100 25064 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.936 0.909 – 0.963 4.41e-06 7095 30462 all phecode
172.21 Basal cell carcinoma Neoplasms 0.902 0.869 – 0.936 6.43e-08 3690 23868 all phecode
172.22 Squamous cell carcinoma Neoplasms 0.973 0.93 – 1.02 0.235 2414 17683 all phecode
172.3 Carcinoma in situ of skin Neoplasms 0.876 0.827 – 0.927 5.76e-06 1482 12326 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.913 0.869 – 0.959 0.000273 1997 18755 all phecode
174 Breast cancer Neoplasms 0.919 0.882 – 0.957 5.64e-05 3186 15514 all phecode
174.1 Breast cancer [female] Neoplasms 0.916 0.878 – 0.956 5.14e-05 3036 14701 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.919 0.88 – 0.959 9.39e-05 2991 14639 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.812 0.703 – 0.937 0.0043 233 2307 all phecode
175 Acquired absence of breast Neoplasms 0.947 0.88 – 1.02 0.142 919 8920 all phecode
180 Cervical cancer and dysplasia Neoplasms 1.02 0.965 – 1.08 0.459 1431 12185 all phecode
180.1 Cervical cancer Neoplasms 1.1 0.996 – 1.21 0.0596 500 4982 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.995 0.931 – 1.06 0.889 1048 9323 all phecode
182 Malignant neoplasm of uterus Neoplasms 1.14 1.05 – 1.24 0.00117 765 7613 all phecode
184 Cancer of other female genital organs Neoplasms 1.02 0.953 – 1.08 0.638 1191 11592 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.983 0.896 – 1.08 0.713 573 5719 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.953 0.857 – 1.06 0.376 432 4309 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.08 0.985 – 1.18 0.104 608 6057 all phecode
185 Cancer of prostate Neoplasms 0.95 0.908 – 0.994 0.0263 2901 10342 all phecode
187 Cancer of other male genital organs Neoplasms 0.998 0.888 – 1.12 0.967 339 3384 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.13 0.919 – 1.38 0.253 115 1141 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.956 0.815 – 1.12 0.578 183 1830 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.886 0.662 – 1.19 0.416 57 562 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.1 1.06 – 1.15 3.52e-06 2923 23541 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.13 1.07 – 1.2 2.35e-05 1450 14437 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.15 1.08 – 1.22 1.07e-05 1267 12655 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.06 0.924 – 1.23 0.384 237 2347 all phecode
189.2 Cancer of bladder Neoplasms 1.07 1.02 – 1.13 0.0112 1783 15224 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.07 1.01 – 1.12 0.0217 1657 14178 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.04 0.953 – 1.13 0.403 678 6586 all phecode
190 Cancer of eye Neoplasms 0.947 0.787 – 1.14 0.568 138 1374 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.989 0.927 – 1.06 0.747 1078 10771 all phecode
191.1 Cancer of brain and nervous system Neoplasms 0.969 0.894 – 1.05 0.439 706 7052 all phecode
191.11 Cancer of brain Neoplasms 0.936 0.858 – 1.02 0.134 600 5996 all phecode
193 Thyroid cancer Neoplasms 1.04 0.973 – 1.12 0.237 945 9393 all phecode
194 Cancer of other endocrine glands Neoplasms 1.04 0.956 – 1.14 0.334 579 5759 all phecode
195 Cancer, suspected or other Neoplasms 1.01 0.984 – 1.03 0.595 16962 26401 all phecode
195.1 Malignant neoplasm, other Neoplasms 1 0.981 – 1.02 0.835 16670 26384 all phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1.03 0.963 – 1.1 0.413 1103 9766 all phecode
196 Radiotherapy Neoplasms 0.918 0.877 – 0.96 0.000217 2427 17006 all phecode
197 Chemotherapy Neoplasms 0.997 0.964 – 1.03 0.848 4952 23797 all phecode
198 Secondary malignant neoplasm Neoplasms 1.01 0.979 – 1.04 0.536 5801 23481 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.992 0.955 – 1.03 0.663 3677 21489 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.03 0.963 – 1.1 0.401 1072 10334 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.03 0.96 – 1.11 0.381 866 8538 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.03 0.951 – 1.11 0.487 767 7558 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.01 0.924 – 1.1 0.881 640 6338 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.01 0.935 – 1.08 0.869 866 8307 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.943 0.836 – 1.06 0.341 336 3253 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.01 0.975 – 1.04 0.716 5693 25767 all phecode
199.4 Neurofibromatosis Neoplasms 1.06 0.847 – 1.32 0.615 88 880 all phecode
200 Myeloproliferative disease Neoplasms 1.07 1.01 – 1.15 0.0321 1113 11098 all phecode
200.1 Polycythemia vera Neoplasms 1.18 1.02 – 1.36 0.0241 231 2310 all phecode
201 Hodgkin's disease Neoplasms 1.14 0.963 – 1.34 0.131 172 1705 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1 0.946 – 1.06 0.993 1559 15571 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.985 0.928 – 1.05 0.621 1329 13268 all phecode
202.21 Nodular lymphoma Neoplasms 0.944 0.869 – 1.03 0.17 693 6923 all phecode
202.22 Reticulosarcoma Neoplasms 1.2 1.02 – 1.41 0.0294 170 1693 all phecode
202.24 Large cell lymphoma Neoplasms 1.06 0.891 – 1.26 0.517 160 1586 all phecode
204 Leukemia Neoplasms 1.07 0.982 – 1.16 0.127 689 6876 all phecode
204.1 Lymphoid leukemia Neoplasms 0.89 0.775 – 1.02 0.101 236 2354 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.879 0.694 – 1.11 0.289 74 734 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.852 0.723 – 1 0.0559 173 1724 all phecode
204.2 Myeloid leukemia Neoplasms 1.09 0.954 – 1.25 0.202 265 2633 all phecode
204.21 Myeloid leukemia, acute Neoplasms 1.08 0.908 – 1.3 0.372 153 1516 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.2 0.896 – 1.61 0.22 61 610 all phecode
204.4 Multiple myeloma Neoplasms 1.21 1.05 – 1.4 0.0076 217 2162 all phecode
208 Benign neoplasm of colon Neoplasms 0.976 0.953 – 1 0.0467 10303 34953 all phecode
209 Neuroendocrine tumors Neoplasms 0.982 0.857 – 1.12 0.794 258 2580 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.991 0.943 – 1.04 0.732 1891 18839 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.07 1.04 – 1.1 2.27e-07 7329 36606 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.07 1.02 – 1.13 0.00738 1843 18412 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.02 0.969 – 1.08 0.422 1677 15527 all phecode
214 Lipoma Neoplasms 0.983 0.927 – 1.04 0.553 1437 14132 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.964 0.895 – 1.04 0.331 883 8710 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.02 0.983 – 1.05 0.353 4528 39509 all phecode
216 Benign neoplasm of skin Neoplasms 0.93 0.91 – 0.951 2.65e-10 11528 34919 all phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 0.845 0.717 – 0.995 0.044 174 1701 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.849 0.806 – 0.895 7.53e-10 1786 17184 all phecode
217.1 Nevus, non-neoplastic Neoplasms 0.849 0.805 – 0.896 2.27e-09 1679 16116 all phecode
218 Benign neoplasm of uterus Neoplasms 0.984 0.949 – 1.02 0.362 4301 16661 all phecode
218.1 Uterine leiomyoma Neoplasms 0.932 0.885 – 0.981 0.0072 1835 15733 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.997 0.959 – 1.04 0.885 3403 16447 all phecode
220 Benign neoplasm of ovary Neoplasms 1.02 0.949 – 1.1 0.587 893 8783 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1 0.956 – 1.05 0.876 2042 14248 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.919 0.862 – 0.98 0.00961 1133 10663 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.05 0.995 – 1.11 0.0772 1801 12657 all phecode
224 Benign neoplasm of eye Neoplasms 0.941 0.865 – 1.02 0.154 691 6752 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.939 0.858 – 1.03 0.166 595 5773 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.04 0.976 – 1.11 0.229 1209 12074 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.03 0.956 – 1.1 0.482 947 9454 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.07 0.94 – 1.21 0.319 289 2890 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.02 0.965 – 1.09 0.424 1329 13264 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.03 0.979 – 1.09 0.249 1690 16896 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.18 1.06 – 1.3 0.00184 467 4644 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.938 0.869 – 1.01 0.104 795 7941 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.08 0.976 – 1.2 0.132 435 4350 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.855 0.816 – 0.897 9.27e-11 2149 20946 all phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.842 0.793 – 0.894 1.54e-08 1356 13336 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.985 0.96 – 1.01 0.253 7767 36615 all phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.976 0.947 – 1 0.103 5743 34218 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.02 0.954 – 1.09 0.549 1031 9761 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.04 0.998 – 1.08 0.0643 2910 22227 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.03 0.988 – 1.08 0.145 2265 19902 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.08 1.02 – 1.15 0.0106 1304 12479 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.06 1 – 1.12 0.0519 1400 13425 all phecode
242.1 Graves' disease Endocrine/metabolic 1.07 0.972 – 1.18 0.169 515 5068 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.07 0.875 – 1.3 0.522 124 1224 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.09 0.963 – 1.24 0.169 292 2898 all phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 1.14 0.951 – 1.36 0.156 144 1432 all phecode
244 Hypothyroidism Endocrine/metabolic 1.08 1.05 – 1.11 6.36e-08 8099 32717 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.02 0.972 – 1.08 0.387 1762 17230 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.06 0.996 – 1.13 0.0685 1261 11982 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.08 1.05 – 1.11 3.7e-08 7542 32208 all phecode
245 Thyroiditis Endocrine/metabolic 1.1 1.02 – 1.18 0.0185 832 7882 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.09 1 – 1.19 0.0413 686 6517 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.09 1 – 1.18 0.0496 679 6449 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.05 1.02 – 1.08 0.00144 6129 30240 all phecode
246.2 Thyroid cyst Endocrine/metabolic 0.87 0.703 – 1.08 0.199 101 960 all phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 0.995 0.926 – 1.07 0.902 886 8696 all phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.31 1.22 – 1.41 2.34e-13 1150 8340 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.25 1.22 – 1.28 2.11e-79 13947 31815 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.28 1.2 – 1.36 5.12e-15 2364 11758 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.14 0.959 – 1.37 0.135 262 960 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.19 1.06 – 1.35 0.00364 551 2686 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.26 1.13 – 1.41 5.32e-05 784 3018 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.26 1.12 – 1.42 0.000126 638 2675 all phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 1.17 0.961 – 1.42 0.118 155 850 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.34 1.3 – 1.37 2.81e-100 9843 29688 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.28 1.1 – 1.5 0.00195 282 1327 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.48 1.4 – 1.57 9.52e-40 1941 13510 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.39 1.3 – 1.49 1.89e-21 1643 9668 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.49 1.42 – 1.57 1.62e-50 2557 16502 all phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.46 1.34 – 1.6 8.58e-18 860 6143 all phecode
250.3 Insulin pump user Endocrine/metabolic 1.41 1.35 – 1.48 1.72e-49 3496 20809 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.15 1.12 – 1.18 1.49e-22 8385 30645 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.08 1.03 – 1.14 0.00342 1870 15861 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.16 1.13 – 1.19 1.25e-22 7553 30071 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.2 0.989 – 1.44 0.065 136 1067 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.49 1.41 – 1.58 9.73e-41 2132 13390 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.2 1.13 – 1.27 1.14e-09 1691 10517 all phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.07 0.997 – 1.15 0.0618 991 8469 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.17 1.09 – 1.26 1.5e-05 1207 8570 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.06 1.01 – 1.1 0.0214 2282 22119 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.05 0.998 – 1.1 0.0599 2088 20335 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.03 0.937 – 1.14 0.526 508 5073 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.06 0.982 – 1.14 0.14 859 8544 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.1 0.961 – 1.25 0.173 263 2621 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.16 0.918 – 1.46 0.215 83 826 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.992 0.86 – 1.14 0.91 226 2250 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.15 0.91 – 1.45 0.246 86 860 all phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 1.1 0.908 – 1.32 0.341 121 1209 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.04 0.853 – 1.28 0.679 108 1080 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.14 1.08 – 1.2 6.74e-06 1506 14869 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.03 0.923 – 1.15 0.582 373 3730 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.07 0.915 – 1.26 0.381 183 1830 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.02 0.843 – 1.23 0.859 135 1350 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.07 0.982 – 1.17 0.121 626 6239 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.08 0.987 – 1.18 0.0969 596 5941 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.17 1.1 – 1.25 1.81e-06 1146 10513 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.33 1.23 – 1.44 1.85e-12 742 7128 all phecode
257 Testicular dysfunction Endocrine/metabolic 1.02 0.951 – 1.09 0.602 1015 9238 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.01 0.947 – 1.09 0.675 983 8933 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.29 1.03 – 1.61 0.025 91 910 all phecode
258.1 Postablative ovarian failure Endocrine/metabolic 1.03 0.837 – 1.27 0.767 109 1090 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.08 1.01 – 1.16 0.0228 1038 10259 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.05 1.01 – 1.1 0.0134 2880 26812 all phecode
260.1 Cachexia Endocrine/metabolic 0.944 0.831 – 1.07 0.376 292 2911 all phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.07 1.01 – 1.13 0.0136 1691 16847 all phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.05 0.961 – 1.15 0.287 614 6140 all phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.08 0.988 – 1.18 0.0914 629 6236 all phecode
260.6 Anorexia Endocrine/metabolic 1.01 0.938 – 1.09 0.791 868 8591 all phecode
260.7 Polyphagia Endocrine/metabolic 1.15 0.881 – 1.5 0.304 65 643 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.12 1.09 – 1.15 1.15e-15 7718 35203 all phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1.19 0.909 – 1.56 0.203 69 690 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.27 1.17 – 1.36 1.03e-09 857 8405 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.11 1.08 – 1.15 1.14e-14 7255 35225 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.99 0.746 – 1.31 0.945 52 511 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.18 1.11 – 1.26 2.58e-07 1182 11676 all phecode
263 Other nutritional deficiency Endocrine/metabolic 1.1 1.04 – 1.16 0.000631 1651 15788 all phecode
264 Lack of normal physiological development Endocrine/metabolic 0.94 0.82 – 1.08 0.377 239 2301 all phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 0.893 0.737 – 1.08 0.25 122 1220 all phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 0.955 0.76 – 1.2 0.695 81 772 all phecode
269 Proteinuria Endocrine/metabolic 1.19 1.13 – 1.25 3.51e-10 1694 13981 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.06 0.986 – 1.13 0.119 967 9575 all phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.916 0.776 – 1.08 0.294 170 1697 all phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.925 0.77 – 1.11 0.405 134 1334 all phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 1.1 0.89 – 1.37 0.372 96 954 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.07 0.992 – 1.16 0.0777 737 7303 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.12 1 – 1.25 0.047 384 3781 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.03 0.791 – 1.33 0.849 71 695 all phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 0.808 0.619 – 1.05 0.116 69 690 all phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.11 0.979 – 1.26 0.103 299 2984 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.02 0.979 – 1.06 0.338 2907 28132 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.02 0.977 – 1.06 0.401 2827 27425 all phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.02 0.828 – 1.27 0.829 102 1007 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.09 1.07 – 1.12 1.21e-15 18881 26670 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.09 1.07 – 1.12 1.01e-15 18843 26654 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.06 1.02 – 1.09 0.000776 5928 21600 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.1 1.03 – 1.16 0.00247 1360 11837 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.12 1.07 – 1.16 1.29e-07 3538 18449 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.02 0.898 – 1.15 0.799 313 3011 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.21 1.16 – 1.26 2.98e-17 2524 22729 all phecode
274.1 Gout Endocrine/metabolic 1.22 1.16 – 1.27 4.98e-18 2409 21991 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.2 1.12 – 1.28 6.03e-08 1082 10576 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.03 0.881 – 1.21 0.705 195 1890 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.02 0.869 – 1.2 0.797 183 1772 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.06 1.02 – 1.09 0.00104 4357 37091 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.872 0.753 – 1.01 0.065 218 2180 all phecode
275.11 Hereditary hemochromatosis Hematopoietic 0.812 0.658 – 1 0.0508 99 990 all phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 0.984 0.747 – 1.3 0.909 62 614 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.16 1.09 – 1.24 6.85e-06 1154 11504 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.05 1.01 – 1.09 0.00774 3369 31544 all phecode
275.51 Hypocalcemia Endocrine/metabolic 1.03 0.959 – 1.11 0.405 898 8969 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.12 1.06 – 1.19 0.000166 1366 13634 all phecode
275.6 Hypercalcemia Endocrine/metabolic 1 0.949 – 1.06 0.866 1468 14183 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.12 1.09 – 1.15 3.16e-19 9238 37046 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.13 1.1 – 1.17 7.81e-18 6352 34366 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.16 1.06 – 1.27 0.00172 550 5434 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.12 1.07 – 1.17 4.65e-07 2514 23219 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.17 1.12 – 1.22 4.42e-14 2992 25216 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.12 1.07 – 1.17 4.17e-06 2148 20909 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.12 1.07 – 1.18 1.59e-06 2086 20332 all phecode
276.41 Acidosis Endocrine/metabolic 1.12 1.06 – 1.18 1.88e-05 1788 17572 all phecode
276.42 Alkalosis Endocrine/metabolic 1.16 1.05 – 1.28 0.00378 476 4741 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.11 1.07 – 1.14 1.1e-09 4574 34527 all phecode
276.6 Fluid overload Endocrine/metabolic 1.27 1.2 – 1.35 7.24e-16 1384 13211 all phecode
276.8 Polydipsia Endocrine/metabolic 0.835 0.69 – 1.01 0.0662 124 1240 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.13 1.09 – 1.17 5.9e-12 4112 35070 all phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.48 1.33 – 1.65 1.54e-12 403 3991 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.959 0.885 – 1.04 0.299 720 7161 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.05 0.982 – 1.13 0.142 936 9270 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.12 1.03 – 1.21 0.00477 773 7668 all phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.32 1.22 – 1.42 1.7e-13 916 8359 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.53 1.5 – 1.56 3.5e-358 19419 27331 all phecode
278.1 Obesity Endocrine/metabolic 1.62 1.59 – 1.66 2.69e-417 17129 27321 all phecode
278.11 Morbid obesity Endocrine/metabolic 1.9 1.84 – 1.95 8.77e-420 8280 27172 all phecode
278.3 Localized adiposity Endocrine/metabolic 1.77 1.57 – 2.01 9.03e-20 324 3228 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.34 1.27 – 1.41 2.13e-31 2104 17411 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.04 0.999 – 1.08 0.0543 2934 28612 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1.01 0.951 – 1.08 0.676 1161 11571 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.967 0.859 – 1.09 0.586 330 3278 all phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 1.03 0.956 – 1.12 0.396 754 7516 all phecode
279.7 Other immunological findings Endocrine/metabolic 1 0.971 – 1.03 0.909 4885 36552 all phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 1.01 0.925 – 1.11 0.804 601 5988 all phecode
280 Iron deficiency anemias Hematopoietic 1.11 1.08 – 1.15 3.23e-10 4626 30873 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.11 1.07 – 1.15 1.52e-09 4484 30649 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.11 1.05 – 1.17 8.3e-05 1771 17196 all phecode
281 Other deficiency anemia Hematopoietic 1.1 0.995 – 1.21 0.0638 519 5120 all phecode
281.1 Megaloblastic anemia Hematopoietic 1.08 0.944 – 1.25 0.253 253 2497 all phecode
281.11 Pernicious anemia Hematopoietic 1.12 0.915 – 1.38 0.266 114 1108 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.1 0.935 – 1.29 0.253 187 1817 all phecode
281.9 Deficiency anemias Hematopoietic 1.06 0.936 – 1.21 0.341 285 2830 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.2 1.06 – 1.36 0.00387 323 3188 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.2 1.03 – 1.4 0.0187 216 2113 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.25 1.07 – 1.47 0.00474 192 1920 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.17 0.989 – 1.4 0.0673 155 1550 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.23 0.936 – 1.62 0.137 64 633 all phecode
284 Aplastic anemia Hematopoietic 1.05 0.966 – 1.14 0.26 697 6943 all phecode
284.1 Pancytopenia Hematopoietic 1.05 0.963 – 1.15 0.268 612 6100 all phecode
285 Other anemias Hematopoietic 1.08 1.06 – 1.11 9.01e-12 11794 33591 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.1 1.06 – 1.14 1.65e-06 3325 27709 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.14 1.09 – 1.2 9.82e-08 2055 19939 all phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.22 1.14 – 1.31 2.52e-08 932 9106 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.06 0.973 – 1.15 0.186 690 6892 all phecode
286 Coagulation defects Hematopoietic 1.1 1.06 – 1.14 3.16e-07 3844 33384 all phecode
286.1 Congenital coagulation defects Hematopoietic 1.06 0.927 – 1.22 0.387 250 2466 all phecode
286.11 Von willebrand's disease Hematopoietic 1.15 0.916 – 1.45 0.228 83 822 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.08 0.897 – 1.31 0.402 126 1260 all phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.13 1.09 – 1.18 1.39e-10 3354 25918 all phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 0.858 0.684 – 1.08 0.186 97 962 all phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 1.15 1 – 1.32 0.0442 254 2529 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.13 0.941 – 1.36 0.19 132 1294 all phecode
286.6 Defibrination syndrome Hematopoietic 1.11 1.06 – 1.16 2.76e-06 2579 25377 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.09 1.05 – 1.13 1.69e-05 3014 29294 all phecode
286.8 Hypercoagulable state Hematopoietic 1.11 1.03 – 1.2 0.00628 846 8437 all phecode
286.81 Primary hypercoagulable state Hematopoietic 1.11 1.03 – 1.19 0.00916 813 8111 all phecode
286.9 Abnormal coagulation profile Hematopoietic 1.14 1.07 – 1.21 8e-05 1182 11487 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.07 1.03 – 1.11 0.00028 3288 28474 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.05 0.909 – 1.22 0.492 211 2094 all phecode
287.3 Thrombocytopenia Hematopoietic 1.07 1.02 – 1.11 0.00203 2938 26323 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.11 1.01 – 1.21 0.0237 601 5994 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.04 0.946 – 1.14 0.437 569 5686 all phecode
287.4 Qualitative platelet defects Hematopoietic 1.27 1.04 – 1.55 0.0199 112 1120 all phecode
288 Diseases of white blood cells Hematopoietic 1.06 1.03 – 1.1 0.000116 4886 36527 all phecode
288.1 Decreased white blood cell count Hematopoietic 0.991 0.938 – 1.05 0.73 1599 15951 all phecode
288.11 Neutropenia Hematopoietic 0.981 0.919 – 1.05 0.557 1106 11041 all phecode
288.2 Elevated white blood cell count Hematopoietic 1.08 1.05 – 1.12 4.67e-06 4082 35079 all phecode
288.3 Eosinophilia Hematopoietic 0.893 0.764 – 1.04 0.153 187 1866 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.03 0.977 – 1.08 0.289 1757 17434 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.991 0.922 – 1.06 0.805 918 9087 all phecode
289.4 Lymphadenitis Hematopoietic 1.05 1.02 – 1.09 0.00479 3888 34715 all phecode
289.5 Diseases of spleen Hematopoietic 1.03 0.924 – 1.15 0.57 393 3913 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.15 1.01 – 1.32 0.037 255 2550 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.12 1 – 1.25 0.0413 385 3813 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.02 0.959 – 1.08 0.549 1318 11547 all phecode
290.1 Dementias Mental Disorders 0.962 0.876 – 1.06 0.419 541 4910 all phecode
290.11 Alzheimer's disease Mental Disorders 1.02 0.851 – 1.22 0.841 151 1389 all phecode
290.12 Dementia with cerebral degenerations Mental Disorders 0.971 0.772 – 1.22 0.805 88 846 all phecode
290.13 Senile dementia Mental Disorders 0.918 0.816 – 1.03 0.15 340 3078 all phecode
290.16 Vascular dementia Mental Disorders 0.85 0.672 – 1.08 0.176 81 777 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.05 0.97 – 1.14 0.231 750 7358 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.935 0.869 – 1.01 0.0686 886 8618 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.02 0.975 – 1.06 0.428 2550 24810 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.96 0.816 – 1.13 0.623 175 1750 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.963 0.874 – 1.06 0.454 484 4807 all phecode
291.8 Alteration of consciousness Mental Disorders 1.04 0.99 – 1.09 0.123 2036 19974 all phecode
292 Neurological disorders Mental Disorders 1.03 0.996 – 1.06 0.0878 5733 38553 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.01 0.961 – 1.06 0.72 2013 19867 all phecode
292.11 Aphasia Mental Disorders 0.991 0.911 – 1.08 0.825 664 6581 all phecode
292.12 Symbolic dysfunction Mental Disorders 1.07 0.921 – 1.24 0.383 200 1988 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.942 0.845 – 1.05 0.289 389 3731 all phecode
292.3 Memory loss Mental Disorders 0.969 0.923 – 1.02 0.219 1922 18158 all phecode
292.4 Altered mental status Mental Disorders 1.07 1.03 – 1.12 0.00176 2454 22725 all phecode
292.5 Transient alteration of awareness Mental Disorders 0.975 0.88 – 1.08 0.63 430 4285 all phecode
292.6 Hallucinations Mental Disorders 1.06 0.911 – 1.22 0.469 217 2147 all phecode
293 Symptoms involving head and neck Mental Disorders 0.839 0.755 – 0.933 0.00114 414 4127 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.03 0.992 – 1.06 0.136 4417 38609 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.06 0.981 – 1.14 0.148 885 8229 all phecode
295.1 Schizophrenia Mental Disorders 1.02 0.848 – 1.22 0.856 138 1339 all phecode
295.2 Paranoid disorders Mental Disorders 1.06 0.86 – 1.29 0.606 118 1079 all phecode
295.3 Psychosis Mental Disorders 1.08 0.997 – 1.17 0.0593 716 6694 all phecode
296 Mood disorders Mental Disorders 1.08 1.05 – 1.1 4.88e-11 15356 20858 all phecode
296.1 Bipolar Mental Disorders 1.15 1.09 – 1.23 4.23e-06 1301 11264 all phecode
296.2 Depression Mental Disorders 1.08 1.06 – 1.1 4.89e-11 14833 20856 all phecode
296.22 Major depressive disorder Mental Disorders 1.08 1.06 – 1.11 5.15e-11 13850 20853 all phecode
297 Suicidal ideation or attempt Mental Disorders 1.12 1.04 – 1.2 0.00213 985 9050 all phecode
297.1 Suicidal ideation Mental Disorders 1.1 1.02 – 1.19 0.017 788 7310 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.09 0.961 – 1.24 0.179 285 2654 all phecode
300 Anxiety disorders Mental Disorders 1.05 1.02 – 1.07 4.54e-05 15419 20850 all phecode
300.1 Anxiety disorder Mental Disorders 1.05 1.03 – 1.08 8.03e-06 14517 20855 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1.04 1.01 – 1.08 0.0131 5546 20512 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.03 0.972 – 1.1 0.291 1360 11377 all phecode
300.13 Phobia Mental Disorders 1.04 0.968 – 1.11 0.294 1051 9542 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.904 0.802 – 1.02 0.0992 328 3018 all phecode
300.4 Dysthymic disorder Mental Disorders 1.04 0.995 – 1.09 0.0785 2420 16552 all phecode
300.8 Acute reaction to stress Mental Disorders 1.01 0.911 – 1.11 0.912 504 4825 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.11 1.03 – 1.2 0.00691 843 7909 all phecode
301 Personality disorders Mental Disorders 1.13 1.02 – 1.25 0.0148 477 4539 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.15 1 – 1.32 0.0446 254 2393 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.986 0.949 – 1.03 0.489 3700 13808 all phecode
302.1 Decreased libido Mental Disorders 0.935 0.845 – 1.04 0.198 447 4331 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.936 0.908 – 0.964 1.16e-05 6808 20043 all phecode
303.1 Dissociative disorder Mental Disorders 1.1 0.924 – 1.3 0.29 161 1573 all phecode
303.3 Psychogenic disorder Mental Disorders 0.928 0.901 – 0.957 1.55e-06 6487 19888 all phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.95 0.86 – 1.05 0.312 471 4623 all phecode
303.4 Somatoform disorder Mental Disorders 1 0.94 – 1.07 0.947 1177 11180 all phecode
304 Adjustment reaction Mental Disorders 1.02 0.987 – 1.06 0.208 3888 20475 all phecode
305.2 Eating disorder Mental Disorders 1.3 1.21 – 1.4 2.84e-12 901 8329 all phecode
306 Other mental disorder Mental Disorders 1.02 0.967 – 1.07 0.494 1815 14133 all phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.09 0.991 – 1.19 0.078 587 3527 all phecode
306.9 Tension headache Mental Disorders 1.01 0.933 – 1.09 0.802 753 7277 all phecode
312 Conduct disorders Mental Disorders 1.09 0.949 – 1.24 0.23 254 2501 all phecode
312.3 Impulse control disorder Mental Disorders 1.05 0.826 – 1.35 0.672 74 736 all phecode
313 Pervasive developmental disorders Mental Disorders 1.06 1 – 1.12 0.0456 1571 14633 all phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1.05 0.994 – 1.12 0.0783 1392 13190 all phecode
313.2 Tics and stuttering Mental Disorders 1.19 0.939 – 1.52 0.148 77 770 all phecode
313.3 Autism Mental Disorders 0.948 0.724 – 1.24 0.696 64 621 all phecode
315 Develomental delays and disorders Mental Disorders 1.08 0.993 – 1.17 0.0713 684 6788 all phecode
315.1 Learning disorder Mental Disorders 1.16 0.935 – 1.44 0.179 87 860 all phecode
315.2 Speech and language disorder Mental Disorders 0.991 0.865 – 1.13 0.893 254 2539 all phecode
316 Substance addiction and disorders Mental Disorders 1.13 1.09 – 1.17 1.02e-10 3682 32680 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.975 0.895 – 1.06 0.566 634 6331 all phecode
317 Alcohol-related disorders Mental Disorders 1.04 0.999 – 1.09 0.0529 2525 22920 all phecode
317.1 Alcoholism Mental Disorders 1.03 0.982 – 1.08 0.225 1986 19339 all phecode
317.11 Alcoholic liver damage Mental Disorders 0.99 0.89 – 1.1 0.849 408 4080 all phecode
318 Tobacco use disorder Mental Disorders 1.16 1.13 – 1.19 1.37e-32 8622 34842 all phecode
320 Meningitis Neurological 1.03 0.919 – 1.15 0.644 382 3820 all phecode
323 Encephalitis Neurological 1.02 0.871 – 1.2 0.782 181 1809 all phecode
323.8 Encephalitis, non-infectious Neurological 1.02 0.859 – 1.22 0.793 153 1527 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.12 0.984 – 1.27 0.0882 288 2880 all phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 1.16 0.866 – 1.56 0.316 53 530 all phecode
327 Sleep disorders Neurological 1.17 1.14 – 1.19 6.32e-48 14941 31602 all phecode
327.1 Hypersomnia Neurological 1.1 1.05 – 1.16 8.59e-05 2061 19110 all phecode
327.3 Sleep apnea Neurological 1.24 1.22 – 1.27 1.81e-73 10909 31304 all phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1.06 0.959 – 1.16 0.265 492 4784 all phecode
327.32 Obstructive sleep apnea Neurological 1.26 1.22 – 1.29 1.98e-67 8744 30530 all phecode
327.4 Insomnia Neurological 1.07 1.04 – 1.1 2.4e-05 5524 30960 all phecode
327.41 Organic or persistent insomnia Neurological 1.03 0.965 – 1.09 0.414 1265 12120 all phecode
327.5 Parasomnia Neurological 1.17 1.08 – 1.28 0.000368 604 5913 all phecode
327.6 Circadian rhythm sleep disorder Neurological 1.08 0.949 – 1.24 0.233 274 2666 all phecode
327.7 Sleep related movement disorders Neurological 1.13 1.07 – 1.19 6.54e-06 1786 17323 all phecode
327.71 Restless legs syndrome Neurological 1.13 1.07 – 1.19 1.44e-05 1570 15360 all phecode
327.72 Sleep related leg cramps Neurological 1.03 0.81 – 1.3 0.821 83 822 all phecode
331 Other cerebral degenerations Neurological 0.959 0.884 – 1.04 0.309 717 7024 all phecode
331.1 Hydrocephalus Neurological 0.964 0.85 – 1.09 0.571 284 2836 all phecode
331.9 Cerebral degeneration, unspecified Neurological 0.984 0.886 – 1.09 0.756 419 4026 all phecode
332 Parkinson's disease Neurological 0.959 0.863 – 1.07 0.432 415 4128 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.04 1 – 1.09 0.0393 2868 26583 all phecode
333.1 Essential tremor Neurological 0.998 0.921 – 1.08 0.956 725 7163 all phecode
333.2 Myoclonus Neurological 1.17 0.993 – 1.38 0.0612 159 1590 all phecode
333.4 Torsion dystonia Neurological 0.827 0.736 – 0.93 0.00144 352 3504 all phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 0.961 0.77 – 1.2 0.728 89 890 all phecode
334 Degenerative disease of the spinal cord Neurological 1.14 1.06 – 1.22 0.000163 1058 10562 all phecode
334.1 Spinocerebellar disease Neurological 1.16 0.914 – 1.48 0.221 79 790 all phecode
334.2 Anterior horn cell disease Neurological 1.13 0.924 – 1.39 0.23 110 1080 all phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 0.996 0.774 – 1.28 0.974 71 693 all phecode
335 Multiple sclerosis Neurological 1.09 0.981 – 1.22 0.107 396 3951 all phecode
337 Disorders of the autonomic nervous system Neurological 1.03 0.95 – 1.11 0.517 808 7413 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.07 0.955 – 1.19 0.251 370 3164 all phecode
338 Pain Neurological 1.07 1.05 – 1.09 1.29e-11 20346 26417 all phecode
338.1 Acute pain Neurological 1.06 1.04 – 1.08 1.07e-07 15582 26313 all phecode
338.2 Chronic pain Neurological 1.11 1.09 – 1.14 6.51e-19 10994 26368 all phecode
339 Other headache syndromes Neurological 1.03 1 – 1.05 0.0249 9242 34658 all phecode
340 Migraine Neurological 1.02 0.996 – 1.05 0.0946 6708 30587 all phecode
340.1 Migrain with aura Neurological 1.02 0.98 – 1.06 0.372 3624 23684 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.08 0.896 – 1.29 0.432 133 1330 all phecode
342 Hemiplegia Neurological 1 0.909 – 1.11 0.938 464 4607 all phecode
343 Infantile cerebral palsy Neurological 1.04 0.826 – 1.31 0.736 85 847 all phecode
344 Other paralytic syndromes Neurological 1.04 0.955 – 1.13 0.387 682 6808 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.02 0.977 – 1.06 0.387 2553 25307 all phecode
345.1 Epilepsy Neurological 1.03 0.947 – 1.11 0.538 747 7465 all phecode
345.11 Generalized convulsive epilepsy Neurological 0.997 0.866 – 1.15 0.962 233 2330 all phecode
345.12 Partial epilepsy Neurological 1 0.916 – 1.1 0.923 534 5335 all phecode
345.3 Convulsions Neurological 1.02 0.978 – 1.07 0.334 2396 23796 all phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.927 0.792 – 1.09 0.349 183 1824 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.01 0.951 – 1.06 0.826 1472 14587 all phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.894 0.735 – 1.09 0.261 120 1181 all phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 0.964 0.777 – 1.19 0.736 110 1100 all phecode
347 Cataplexy and narcolepsy Neurological 1.15 0.925 – 1.44 0.206 101 1010 all phecode
348 Other conditions of brain Neurological 1.06 1.01 – 1.12 0.0205 1793 17894 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.06 0.987 – 1.14 0.108 905 9034 all phecode
348.4 Cerebral cysts Neurological 1.01 0.869 – 1.17 0.932 229 2290 all phecode
348.7 Coma Neurological 0.987 0.857 – 1.14 0.859 229 2275 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.1 1.02 – 1.18 0.0155 853 8479 all phecode
348.9 Other conditions of brain, NOS Neurological 0.986 0.943 – 1.03 0.529 2341 23287 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.05 0.976 – 1.12 0.199 941 9385 all phecode
350 Abnormal movement Neurological 1.03 1 – 1.06 0.0261 6706 38762 all phecode
350.1 Abnormal involuntary movements Neurological 1.04 0.997 – 1.08 0.0687 3273 30524 all phecode
350.2 Abnormality of gait Neurological 1.05 1.01 – 1.08 0.0141 3920 30520 all phecode
350.3 Lack of coordination Neurological 0.948 0.887 – 1.01 0.11 1062 10554 all phecode
350.5 Abnormal reflex Neurological 0.968 0.831 – 1.13 0.674 200 1988 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.962 0.877 – 1.05 0.406 558 5576 all phecode
351 Other peripheral nerve disorders Neurological 1.09 1.06 – 1.12 7.46e-11 7401 34460 all phecode
352 Disorders of other cranial nerves Neurological 1.02 0.97 – 1.08 0.417 1714 17106 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1 0.915 – 1.1 0.924 535 5344 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.05 0.973 – 1.13 0.211 783 7826 all phecode
353 Nerve root and plexus disorders Neurological 1.07 1.04 – 1.11 6.39e-05 4256 33369 all phecode
353.1 Nerve plexus lesions Neurological 1.08 0.967 – 1.2 0.173 390 3900 all phecode
353.2 Nerve root lesions Neurological 1.04 0.858 – 1.26 0.678 130 1287 all phecode
355 Complex regional/central pain syndrome Neurological 1.11 1.01 – 1.22 0.031 531 5295 all phecode
355.1 Chronic pain syndrome Neurological 1.17 1.09 – 1.26 3.03e-05 843 8386 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.06 1.01 – 1.11 0.0161 2335 20731 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.09 1.05 – 1.13 3.47e-06 3472 29956 all phecode
358 Myoneural disorders Neurological 1.1 1.03 – 1.17 0.0029 1147 11391 all phecode
358.1 Myasthenia gravis Neurological 0.918 0.747 – 1.13 0.414 109 1082 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.955 0.895 – 1.02 0.163 1134 11274 all phecode
359.1 Muscular dystrophies Neurological 0.963 0.722 – 1.28 0.794 64 632 all phecode
359.2 Myopathy Neurological 0.967 0.905 – 1.03 0.322 1092 10843 all phecode
360 Disorders of the globe Sense Organs 0.893 0.741 – 1.08 0.231 131 1276 all phecode
360.2 Progressive myopia Sense Organs 0.806 0.616 – 1.05 0.116 65 640 all phecode
361 Retinal detachments and defects Sense Organs 0.95 0.877 – 1.03 0.207 733 7131 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.873 0.769 – 0.991 0.0359 302 2962 all phecode
362 Other retinal disorders Sense Organs 0.978 0.941 – 1.02 0.249 3569 22997 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.964 0.918 – 1.01 0.137 2172 15483 all phecode
362.21 Macular degeneration, dry Sense Organs 0.869 0.777 – 0.971 0.0131 419 3438 all phecode
362.22 Macular degeneration, wet Sense Organs 0.968 0.804 – 1.16 0.728 148 1184 all phecode
362.23 Cystoid macular degeneration of retina Sense Organs 0.939 0.843 – 1.05 0.256 408 3839 all phecode
362.26 Macular puckering of retina Sense Organs 0.967 0.902 – 1.04 0.353 976 8610 all phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.875 0.791 – 0.968 0.00985 488 4558 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.964 0.915 – 1.02 0.166 1883 13955 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.04 0.965 – 1.11 0.332 976 8527 all phecode
362.31 Separation of retinal layers Sense Organs 1.01 0.907 – 1.12 0.904 413 4056 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.01 0.928 – 1.1 0.803 662 5933 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.89 0.796 – 0.994 0.0395 392 3787 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.928 0.801 – 1.08 0.321 215 2103 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.21 1.05 – 1.39 0.00655 241 2368 all phecode
362.9 Retinal edema Sense Organs 1.17 1.04 – 1.32 0.0111 324 2936 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.911 0.826 – 1 0.0619 492 4746 all phecode
363.3 Chorioretinal scars Sense Organs 0.873 0.776 – 0.982 0.0239 332 3184 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.962 0.901 – 1.03 0.244 1132 10772 all phecode
364.1 Corneal opacity Sense Organs 0.961 0.863 – 1.07 0.474 394 3846 all phecode
364.2 Corneal edema Sense Organs 1.1 0.912 – 1.33 0.31 123 1208 all phecode
364.4 Corneal degenerations Sense Organs 0.944 0.848 – 1.05 0.297 402 3962 all phecode
364.41 Keratoconus Sense Organs 0.74 0.578 – 0.949 0.0176 75 739 all phecode
364.5 Corneal dystrophy Sense Organs 0.998 0.903 – 1.1 0.965 502 4682 all phecode
364.51 Fuchs' dystrophy Sense Organs 0.946 0.823 – 1.09 0.434 266 2521 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.887 0.708 – 1.11 0.298 91 885 all phecode
365 Glaucoma Sense Organs 0.966 0.925 – 1.01 0.119 2672 21326 all phecode
365.1 Open-angle glaucoma Sense Organs 0.959 0.883 – 1.04 0.321 705 6491 all phecode
365.11 Primary open angle glaucoma Sense Organs 0.927 0.831 – 1.03 0.176 403 3681 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.949 0.823 – 1.09 0.47 251 2370 all phecode
366 Cataract Sense Organs 0.987 0.96 – 1.01 0.348 8611 28043 all phecode
366.1 Nonsenile Cataract Sense Organs 0.904 0.776 – 1.05 0.196 207 1979 all phecode
366.2 Senile cataract Sense Organs 0.974 0.942 – 1.01 0.108 5480 24980 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.969 0.945 – 0.994 0.0142 8967 37779 all phecode
367.1 Myopia Sense Organs 0.948 0.919 – 0.979 0.00111 5014 34677 all phecode
367.2 Astigmatism Sense Organs 0.947 0.915 – 0.98 0.00206 4161 32463 all phecode
367.8 Hypermetropia Sense Organs 0.935 0.89 – 0.981 0.00652 2039 18599 all phecode
367.9 Blindness and low vision Sense Organs 1.03 0.972 – 1.1 0.29 1277 12356 all phecode
368 Visual disturbances Sense Organs 1.01 0.982 – 1.04 0.47 5715 39599 all phecode
368.1 Amblyopia Sense Organs 1.04 0.959 – 1.14 0.323 651 6479 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.02 0.954 – 1.09 0.588 1087 10786 all phecode
368.3 Anisometropia Sense Organs 0.86 0.744 – 0.995 0.0426 219 2168 all phecode
368.4 Visual field defects Sense Organs 1.01 0.943 – 1.07 0.869 1132 11173 all phecode
368.9 Subjective visual disturbances Sense Organs 0.999 0.935 – 1.07 0.979 1070 10620 all phecode
368.91 Psychophysical visual disturbances Sense Organs 1.16 0.952 – 1.41 0.142 120 1171 all phecode
369 Infection of the eye Sense Organs 0.937 0.901 – 0.974 0.00102 3185 28240 all phecode
369.2 Eye infection, viral Sense Organs 0.938 0.85 – 1.03 0.198 502 4954 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.938 0.899 – 0.978 0.00273 2716 24970 all phecode
370 Keratitis Sense Organs 0.933 0.879 – 0.989 0.0205 1365 13169 all phecode
370.1 Corneal ulcer Sense Organs 0.937 0.812 – 1.08 0.372 223 2194 all phecode
370.2 Superficial keratitis Sense Organs 0.938 0.856 – 1.03 0.175 546 5393 all phecode
370.3 Keratoconjunctivitis Sense Organs 0.968 0.889 – 1.05 0.46 649 6263 all phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.951 0.806 – 1.12 0.555 179 1677 all phecode
371 Inflammation of the eye Sense Organs 0.948 0.916 – 0.98 0.00181 4414 32310 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.994 0.906 – 1.09 0.903 541 5278 all phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.964 0.897 – 1.04 0.316 906 8939 all phecode
371.21 Allergic conjunctivitis Sense Organs 0.956 0.883 – 1.03 0.261 756 7515 all phecode
371.3 Inflammation of eyelids Sense Organs 0.935 0.9 – 0.972 0.000586 3398 26983 all phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 0.798 0.658 – 0.967 0.0216 133 1291 all phecode
372 Disorders of conjunctiva Sense Organs 0.944 0.884 – 1.01 0.079 1118 10728 all phecode
374 Other disorders of eyelids Sense Organs 0.931 0.893 – 0.969 0.000564 2940 24188 all phecode
374.1 Ectropion or entropion Sense Organs 0.87 0.784 – 0.965 0.00872 431 4084 all phecode
374.2 Lagophthalmos Sense Organs 0.972 0.844 – 1.12 0.689 235 2335 all phecode
374.3 Ptosis of eyelid Sense Organs 0.93 0.871 – 0.993 0.0297 1102 10734 all phecode
374.6 Dermatochalasis Sense Organs 0.98 0.916 – 1.05 0.566 1040 9720 all phecode
375 Disorders of lacrimal system Sense Organs 0.971 0.936 – 1.01 0.127 3694 26045 all phecode
375.1 Dry eyes Sense Organs 0.97 0.936 – 1.01 0.0997 4040 26751 all phecode
375.2 Epiphora Sense Organs 0.946 0.853 – 1.05 0.299 442 4354 all phecode
376 Disorders of the orbit Sense Organs 1 0.895 – 1.13 0.938 352 3508 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.07 0.992 – 1.15 0.0832 913 9021 all phecode
377.1 Optic atrophy Sense Organs 0.975 0.855 – 1.11 0.706 283 2793 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.09 1 – 1.2 0.0493 585 5775 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.969 0.912 – 1.03 0.309 1275 12460 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.981 0.91 – 1.06 0.622 828 8130 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.932 0.791 – 1.1 0.398 170 1686 all phecode
378.5 Paralytic strabismus Sense Organs 0.948 0.845 – 1.06 0.356 349 3437 all phecode
379 Other disorders of eye Sense Organs 0.957 0.926 – 0.989 0.00802 5046 29999 all phecode
379.1 Scleritis and episcleritis Sense Organs 0.945 0.8 – 1.12 0.506 176 1743 all phecode
379.2 Disorders of vitreous body Sense Organs 0.944 0.909 – 0.981 0.00333 3634 23186 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.865 0.718 – 1.04 0.126 135 1258 all phecode
379.4 Anomalies of pupillary function Sense Organs 0.988 0.871 – 1.12 0.852 287 2833 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.06 0.936 – 1.2 0.359 304 2948 all phecode
379.51 Pigmentary iris degeneration Sense Organs 0.853 0.659 – 1.1 0.226 77 731 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.02 0.953 – 1.09 0.617 1129 11130 all phecode
380 Disorders of external ear Sense Organs 0.907 0.866 – 0.95 3.5e-05 2242 20393 all phecode
380.1 Otitis externa Sense Organs 0.985 0.931 – 1.04 0.593 1469 14580 all phecode
380.4 Impacted cerumen Sense Organs 0.9 0.863 – 0.94 1.53e-06 2648 23557 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1 0.968 – 1.04 0.95 4255 36417 all phecode
381.1 Otitis media Sense Organs 1.03 0.994 – 1.07 0.0934 3079 29813 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.03 0.988 – 1.07 0.168 2610 25602 all phecode
381.2 Eustachian tube disorders Sense Organs 0.922 0.876 – 0.97 0.00173 1816 17827 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.11 0.932 – 1.32 0.244 153 1530 all phecode
381.9 Otorrhea Sense Organs 1.14 1.02 – 1.27 0.025 372 3713 all phecode
382 Otalgia Sense Organs 1.01 0.961 – 1.06 0.696 1884 18673 all phecode
383 Otosclerosis Sense Organs 0.906 0.749 – 1.1 0.31 124 1240 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.01 0.915 – 1.1 0.907 516 5156 all phecode
384.1 Myringitis Sense Organs 0.812 0.597 – 1.1 0.183 51 502 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.03 0.925 – 1.15 0.599 403 4029 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1 0.904 – 1.11 0.965 432 4320 all phecode
385.3 Cholesteatoma Sense Organs 1.02 0.894 – 1.15 0.809 277 2770 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.991 0.818 – 1.2 0.929 118 1180 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.03 0.981 – 1.09 0.227 1882 18186 all phecode
386.1 Meniere's disease Sense Organs 1.05 0.926 – 1.19 0.463 319 3156 all phecode
386.2 Peripheral or central vertigo Sense Organs 1.04 0.981 – 1.1 0.196 1586 15423 all phecode
386.21 Central origin vertigo Sense Organs 1.05 0.984 – 1.12 0.148 1208 11844 all phecode
386.3 Labyrinthitis Sense Organs 1.03 0.975 – 1.09 0.272 1482 14530 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.03 1 – 1.06 0.0311 6933 38286 all phecode
388 Other disorders of ear Sense Organs 0.986 0.919 – 1.06 0.692 960 9501 all phecode
389 Hearing loss Sense Organs 0.982 0.957 – 1.01 0.179 8182 38069 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.938 0.906 – 0.971 0.000337 4107 29258 all phecode
389.2 Conductive hearing loss Sense Organs 0.971 0.905 – 1.04 0.426 905 9042 all phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.913 0.78 – 1.07 0.257 192 1808 all phecode
389.4 Tinnitus Sense Organs 0.926 0.884 – 0.969 0.000867 2291 22130 all phecode
389.5 Disorders of acoustic nerve Sense Organs 1.03 0.856 – 1.25 0.734 124 1229 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.06 1 – 1.13 0.0348 1458 13732 all phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 1.11 0.986 – 1.24 0.0844 350 3415 all phecode
394.2 Mitral valve disease Circulatory System 1.01 0.915 – 1.12 0.819 462 4560 all phecode
394.3 Aortic valve disease Circulatory System 1.11 0.936 – 1.31 0.236 176 1691 all phecode
394.4 Acute rheumatic heart disease Circulatory System 1 0.761 – 1.32 0.98 55 546 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.06 0.971 – 1.16 0.184 587 5739 all phecode
395 Heart valve disorders Circulatory System 1.02 0.988 – 1.06 0.196 3976 28748 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.966 0.922 – 1.01 0.145 2175 20441 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.09 1.04 – 1.15 0.000492 2060 17194 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.05 0.949 – 1.16 0.359 493 4864 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.09 0.885 – 1.34 0.418 108 1080 all phecode
395.6 Heart valve replaced Circulatory System 1.06 0.997 – 1.13 0.061 1177 10833 all phecode
396 Abnormal heart sounds Circulatory System 1.03 1 – 1.07 0.041 4718 34395 all phecode
401 Hypertension Circulatory System 1.27 1.25 – 1.3 1.26e-102 23317 23367 all phecode
401.1 Essential hypertension Circulatory System 1.28 1.25 – 1.3 2.16e-103 23158 23364 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.4 1.34 – 1.46 1.66e-52 3503 14616 all phecode
401.21 Hypertensive heart disease Circulatory System 1.34 1.24 – 1.44 6.95e-14 893 6607 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.38 1.31 – 1.45 1.25e-39 2584 13072 all phecode
401.3 Other hypertensive complications Circulatory System 1.26 1.21 – 1.32 4.62e-24 2679 15833 all phecode
411 Ischemic Heart Disease Circulatory System 1.17 1.13 – 1.2 3.82e-29 8807 30299 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.21 1.13 – 1.31 1.62e-07 937 8574 all phecode
411.2 Myocardial infarction Circulatory System 1.2 1.15 – 1.24 2.3e-20 3594 21716 all phecode
411.3 Angina pectoris Circulatory System 1.2 1.15 – 1.25 1.95e-15 2485 18304 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.16 1.13 – 1.2 4.06e-25 7555 27492 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.17 0.981 – 1.39 0.0801 156 1529 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.17 1.13 – 1.21 2.36e-23 6331 25741 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.22 1.1 – 1.35 0.000191 442 4211 all phecode
414 Other forms of chronic heart disease Circulatory System 1.12 1.08 – 1.17 1.45e-08 3101 22616 all phecode
414.2 ASCVD Circulatory System 1.12 1.03 – 1.22 0.00597 718 6816 all phecode
415 Pulmonary heart disease Circulatory System 1.15 1.1 – 1.19 9.15e-13 3366 30208 all phecode
415.1 Acute pulmonary heart disease Circulatory System 1.14 1.08 – 1.2 3.12e-07 1912 19014 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.14 1.08 – 1.2 2.86e-07 1906 18953 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.17 1.11 – 1.23 2.23e-09 1808 17605 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.12 1.04 – 1.22 0.00489 706 7032 all phecode
416 Cardiomegaly Circulatory System 1.11 1.04 – 1.18 0.00135 1254 12372 all phecode
418 Nonspecific chest pain Circulatory System 1.05 1.03 – 1.07 1.75e-05 12650 33952 all phecode
418.1 Precordial pain Circulatory System 1.03 0.972 – 1.09 0.329 1471 13782 all phecode
420 Carditis Circulatory System 1.05 0.998 – 1.11 0.061 1588 15680 all phecode
420.1 Myocarditis Circulatory System 1.16 0.929 – 1.45 0.189 97 958 all phecode
420.2 Pericarditis Circulatory System 1.05 0.969 – 1.13 0.249 842 8402 all phecode
420.21 Acute pericarditis Circulatory System 1.2 1.02 – 1.41 0.0296 177 1764 all phecode
420.22 Chronic pericarditis Circulatory System 1.26 1.03 – 1.53 0.026 117 1153 all phecode
420.3 Endocarditis Circulatory System 1.09 1.01 – 1.18 0.0289 764 7535 all phecode
425 Cardiomyopathy Circulatory System 1.11 1.06 – 1.17 1.16e-05 2078 19881 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.12 1.07 – 1.18 4.79e-06 1989 19025 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.05 0.906 – 1.22 0.513 208 2050 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.1 0.942 – 1.27 0.238 201 1992 all phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.01 0.893 – 1.14 0.877 317 3170 all phecode
425.8 Other cardiomyopathy Circulatory System 1.09 0.87 – 1.37 0.454 95 931 all phecode
426 Cardiac conduction disorders Circulatory System 1.08 1.05 – 1.1 3.2e-09 12327 25440 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.14 1.08 – 1.2 2.48e-06 1903 11501 all phecode
426.21 First degree AV block Circulatory System 1.1 1.03 – 1.17 0.00286 1313 8899 all phecode
426.22 Mobitz II AV block Circulatory System 0.876 0.658 – 1.17 0.365 64 553 all phecode
426.23 Second degree AV block Circulatory System 1 0.862 – 1.16 0.99 216 1925 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.09 0.984 – 1.21 0.0963 461 3823 all phecode
426.25 Other heart block Circulatory System 1.05 0.902 – 1.23 0.513 203 1803 all phecode
426.3 Bundle branch block Circulatory System 1.1 1.05 – 1.16 4.47e-05 2306 13999 all phecode
426.31 Right bundle branch block Circulatory System 1.09 1.03 – 1.16 0.0047 1423 10758 all phecode
426.32 Left bundle branch block Circulatory System 1.14 1.06 – 1.23 0.000283 969 8110 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.937 0.741 – 1.19 0.589 82 820 all phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.08 1.05 – 1.1 2.06e-08 10577 25186 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.16 1.07 – 1.26 0.000595 679 6650 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.12 1.06 – 1.18 5.25e-05 1754 11536 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.13 1.06 – 1.2 0.000393 1171 8184 all phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.11 1.03 – 1.2 0.00518 846 7320 all phecode
427 Cardiac dysrhythmias Circulatory System 1.06 1.04 – 1.08 1.48e-07 17397 25735 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.05 1.01 – 1.1 0.0192 2474 18178 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.05 0.997 – 1.11 0.0634 1595 14293 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.08 1.01 – 1.15 0.0248 1181 9915 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.11 1.08 – 1.15 1.25e-09 5313 18688 all phecode
427.21 Atrial fibrillation Circulatory System 1.11 1.07 – 1.15 5.18e-09 5188 18409 all phecode
427.22 Atrial flutter Circulatory System 1.1 1.04 – 1.16 0.00122 1693 11042 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.06 1.03 – 1.09 5.25e-05 8688 25552 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.04 0.948 – 1.14 0.393 536 5233 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.903 0.781 – 1.04 0.17 216 2118 all phecode
427.42 Cardiac arrest Circulatory System 1.07 0.959 – 1.19 0.227 410 4034 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.05 1.02 – 1.08 0.000561 6905 25457 all phecode
427.6 Premature beats Circulatory System 1.02 0.977 – 1.07 0.333 2359 16248 all phecode
427.61 Supraventricular premature beats Circulatory System 1.07 0.985 – 1.17 0.106 670 6287 all phecode
427.7 Tachycardia NOS Circulatory System 1.1 1.06 – 1.13 7.3e-09 5124 25531 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.08 0.999 – 1.16 0.0529 912 7501 all phecode
427.9 Palpitations Circulatory System 0.994 0.961 – 1.03 0.747 4430 24505 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.22 1.18 – 1.26 1.84e-27 4300 23663 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.22 1.18 – 1.27 3.74e-26 3756 22446 all phecode
428.2 Heart failure NOS Circulatory System 1.25 1.2 – 1.29 1.06e-29 3701 21722 all phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.19 1.13 – 1.26 6.58e-11 1765 14476 all phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.3 1.23 – 1.37 3.47e-20 1648 13395 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.07 1.05 – 1.09 3.98e-09 12635 32504 all phecode
429.1 Heart transplant/surgery Circulatory System 1.1 1.03 – 1.17 0.00243 1219 11696 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.1 1.07 – 1.13 4.56e-10 6322 29232 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.06 1.03 – 1.08 4.81e-06 9650 32421 all phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.11 1.02 – 1.2 0.0109 723 7072 all phecode
430 Intracranial hemorrhage Circulatory System 0.974 0.902 – 1.05 0.496 789 7842 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.968 0.848 – 1.11 0.634 261 2610 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1.03 0.92 – 1.16 0.594 368 3671 all phecode
430.3 Subdural hemorrhage Circulatory System 0.903 0.793 – 1.03 0.126 272 2680 all phecode
433 Cerebrovascular disease Circulatory System 1.07 1.04 – 1.1 3.02e-05 5463 32242 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.06 1.01 – 1.12 0.0182 1978 16212 all phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.14 0.994 – 1.31 0.0605 260 2517 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.11 0.872 – 1.42 0.389 80 789 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.1 1.05 – 1.14 5.08e-05 2437 21732 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.09 1.05 – 1.14 9.09e-05 2357 21103 all phecode
433.3 Cerebral ischemia Circulatory System 1.03 0.985 – 1.07 0.218 2780 22868 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.05 1 – 1.09 0.0495 2409 20762 all phecode
433.5 Cerebral aneurysm Circulatory System 0.987 0.894 – 1.09 0.802 474 4724 all phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.05 0.953 – 1.17 0.308 464 4518 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.11 1.02 – 1.2 0.0153 695 6822 all phecode
440 Atherosclerosis Circulatory System 1.13 1.08 – 1.18 9.82e-08 2477 19724 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.993 0.861 – 1.15 0.925 231 2291 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.13 1.07 – 1.2 1.91e-05 1516 13532 all phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.23 1.08 – 1.4 0.00153 274 2669 all phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.11 1.04 – 1.19 0.00264 1040 9647 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.18 1.09 – 1.27 2.39e-05 846 8124 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.04 0.949 – 1.15 0.378 515 5115 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.06 0.921 – 1.21 0.429 240 2387 all phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1 0.843 – 1.19 0.984 154 1536 all phecode
442 Other aneurysm Circulatory System 1.08 1.04 – 1.13 0.000179 2779 21466 all phecode
442.1 Aortic aneurysm Circulatory System 1.09 1.04 – 1.15 0.000289 2054 16492 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.07 1 – 1.14 0.0346 1189 10558 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.13 0.972 – 1.32 0.11 202 2002 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.991 0.843 – 1.16 0.908 179 1765 all phecode
442.4 Arterial dissection Circulatory System 0.919 0.784 – 1.08 0.294 184 1840 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.05 0.945 – 1.17 0.35 399 3978 all phecode
443 Peripheral vascular disease Circulatory System 1.08 1.04 – 1.12 0.000241 3086 24814 all phecode
443.1 Raynaud's syndrome Circulatory System 0.872 0.804 – 0.945 0.000847 742 7390 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.33 1.15 – 1.54 0.000118 220 2087 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.08 1.03 – 1.13 0.000534 2557 21985 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.14 1.09 – 1.2 1.1e-08 2341 18862 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.1 1.02 – 1.19 0.00933 848 8423 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.05 0.931 – 1.18 0.431 313 3099 all phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 1.05 0.886 – 1.24 0.577 155 1548 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.979 0.884 – 1.08 0.674 460 4559 all phecode
446.4 Wegener's granulomatosis Circulatory System 0.801 0.652 – 0.984 0.0345 109 1075 all phecode
446.5 Giant cell arteritis Circulatory System 0.794 0.62 – 1.02 0.0673 79 749 all phecode
446.9 Arteritis NOS Circulatory System 1.05 0.927 – 1.19 0.441 289 2876 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.08 1.04 – 1.13 0.000316 2647 22765 all phecode
447.1 Stricture of artery Circulatory System 1.11 1.01 – 1.22 0.0297 523 5163 all phecode
447.7 Aortic ectasia Circulatory System 1.05 0.972 – 1.13 0.223 804 7938 all phecode
448 Disease of capillaries Circulatory System 0.864 0.812 – 0.92 4.63e-06 1237 12127 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.08 1.03 – 1.13 0.0014 2104 20985 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.03 0.951 – 1.12 0.465 738 7355 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.06 0.92 – 1.22 0.432 244 2437 all phecode
452 Other venous embolism and thrombosis Circulatory System 1.12 1.09 – 1.16 8.31e-13 4957 29867 all phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1.02 0.894 – 1.16 0.798 276 2747 all phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1.12 1.08 – 1.17 3.77e-09 3260 26940 all phecode
452.8 Postphlebitic syndrome Circulatory System 1.13 0.952 – 1.33 0.164 154 1529 all phecode
453 Chronic venous hypertension Circulatory System 1.07 0.925 – 1.24 0.351 220 2168 all phecode
454 Varicose veins Circulatory System 1.06 1.02 – 1.11 0.00353 2827 24555 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1.09 1.04 – 1.14 0.000164 2469 21426 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.1 1.04 – 1.16 0.000535 1565 15056 all phecode
455 Hemorrhoids Circulatory System 0.969 0.94 – 0.999 0.0398 5799 29818 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.1 1.06 – 1.14 4.09e-06 3097 24898 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.11 1.06 – 1.16 3.77e-05 2095 15309 all phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.11 0.989 – 1.25 0.0745 324 3221 all phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.1 1.05 – 1.16 0.000102 1973 14689 all phecode
458 Hypotension Circulatory System 1.12 1.09 – 1.16 1.75e-12 5091 32185 all phecode
458.1 Orthostatic hypotension Circulatory System 1.09 1.02 – 1.15 0.00641 1344 12938 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.12 1.05 – 1.2 0.000532 1109 11012 all phecode
458.9 Hypotension NOS Circulatory System 1.12 1.09 – 1.16 5.64e-12 4618 31186 all phecode
459 Other disorders of circulatory system Circulatory System 1.09 1.07 – 1.12 3.11e-11 7825 34792 all phecode
459.1 Hemorrhage NOS Circulatory System 1.02 0.948 – 1.1 0.566 834 8215 all phecode
459.7 Blood vessel replaced Circulatory System 1.19 1.12 – 1.27 1.09e-08 1305 13023 all phecode
459.9 Circulatory disease NEC Circulatory System 1.09 1.06 – 1.12 1.19e-09 6706 33592 all phecode
464 Acute sinusitis Respiratory 0.967 0.936 – 0.999 0.041 4792 32137 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.967 0.944 – 0.991 0.00708 9601 35915 all phecode
465.2 Acute pharyngitis Respiratory 0.963 0.933 – 0.993 0.0163 5310 32365 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.04 0.938 – 1.15 0.456 443 4428 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.915 0.869 – 0.963 0.000623 1797 17640 all phecode
471 Nasal polyps Respiratory 0.945 0.865 – 1.03 0.207 592 5881 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.967 0.919 – 1.02 0.207 1797 16986 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1.02 0.985 – 1.07 0.23 2983 25244 all phecode
473.1 Chronic laryngitis Respiratory 1.01 0.787 – 1.29 0.963 68 674 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.984 0.903 – 1.07 0.711 628 6254 all phecode
473.4 Voice disturbance Respiratory 1.03 0.986 – 1.08 0.184 2336 21975 all phecode
474 Acute and chronic tonsillitis Respiratory 1 0.933 – 1.08 0.925 880 7892 all phecode
474.1 Acute tonsillitis Respiratory 0.87 0.772 – 0.979 0.0213 335 3181 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.03 0.952 – 1.12 0.436 700 6445 all phecode
475 Chronic sinusitis Respiratory 0.96 0.928 – 0.993 0.0184 4378 27891 all phecode
475.9 Postnasal drip Respiratory 0.865 0.805 – 0.93 8.47e-05 922 9017 all phecode
476 Allergic rhinitis Respiratory 0.984 0.963 – 1.01 0.169 12687 28117 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.09 1.02 – 1.16 0.00722 1150 11318 all phecode
478 Throat pain Respiratory 0.985 0.887 – 1.09 0.783 426 4195 all phecode
479 Other upper respiratory disease Respiratory 0.994 0.964 – 1.02 0.681 5627 28048 all phecode
480 Pneumonia Respiratory 1.08 1.05 – 1.12 6.12e-08 5947 37034 all phecode
480.1 Bacterial pneumonia Respiratory 1.1 1.04 – 1.18 0.0022 1155 11495 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.12 1.02 – 1.23 0.0147 568 5644 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.08 0.907 – 1.28 0.39 153 1523 all phecode
480.13 MRSA pneumonia Respiratory 1.14 0.939 – 1.39 0.185 117 1165 all phecode
480.2 Viral pneumonia Respiratory 1.24 1.06 – 1.44 0.00645 202 1992 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.06 0.892 – 1.25 0.52 159 1590 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.11 0.923 – 1.34 0.268 135 1312 all phecode
481 Influenza Respiratory 1.02 0.963 – 1.08 0.479 1355 13284 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.04 0.997 – 1.08 0.0702 3412 29871 all phecode
495 Asthma Respiratory 1.11 1.09 – 1.14 2.81e-17 8671 33569 all phecode
495.1 Chronic obstructive asthma Respiratory 1.22 1.09 – 1.36 0.00038 397 3925 all phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 1.23 0.961 – 1.58 0.0998 81 802 all phecode
495.2 Asthma with exacerbation Respiratory 1.08 1.02 – 1.14 0.0057 1629 16033 all phecode
496 Chronic airway obstruction Respiratory 1.17 1.13 – 1.21 2.28e-22 5343 28343 all phecode
496.1 Emphysema Respiratory 1.13 1.08 – 1.19 2.42e-07 2134 19414 all phecode
496.2 Chronic bronchitis Respiratory 1.21 1.17 – 1.26 1.97e-27 4128 26624 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.22 1.18 – 1.27 2.49e-27 3747 25467 all phecode
496.3 Bronchiectasis Respiratory 0.998 0.908 – 1.1 0.963 549 5453 all phecode
497 Bronchitis Respiratory 1.09 1.04 – 1.14 0.000841 1946 18824 all phecode
498 Acute bronchospasm Respiratory 1.29 1.17 – 1.43 3.72e-07 496 4943 all phecode
499 Cystic fibrosis Respiratory 1.05 0.886 – 1.26 0.551 151 1510 all phecode
500 Lung disease due to external agents Respiratory 1.12 1.02 – 1.23 0.0166 557 5551 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.06 0.851 – 1.32 0.609 92 920 all phecode
500.2 Pneumoconiosis Respiratory 1.13 0.896 – 1.43 0.3 78 764 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.12 1.02 – 1.22 0.0119 634 6225 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.04 0.964 – 1.12 0.312 815 8076 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.19 1.11 – 1.29 3.95e-06 835 8243 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.05 0.956 – 1.15 0.323 595 5878 all phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 0.999 0.884 – 1.13 0.993 311 3084 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.12 1.07 – 1.19 2.03e-05 1638 15749 all phecode
506 Empyema and pneumothorax Respiratory 1.09 1.05 – 1.14 3.06e-05 2894 25235 all phecode
507 Pleurisy; pleural effusion Respiratory 1.13 1.08 – 1.18 5.12e-09 2916 26208 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.11 1.06 – 1.16 7.26e-06 2382 22588 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.14 1.1 – 1.18 8.84e-14 4032 29477 all phecode
509.1 Respiratory failure Respiratory 1.18 1.12 – 1.24 7.63e-11 1937 18949 all phecode
509.2 Respiratory insufficiency Respiratory 1.12 1.05 – 1.19 0.000725 1174 11679 all phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.12 1.07 – 1.18 1.66e-05 1689 16489 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.19 1.13 – 1.26 4.08e-11 1741 17249 all phecode
510 Other diseases of lung Respiratory 1.04 1.01 – 1.07 0.0202 5503 35907 all phecode
510.2 Lung transplant Respiratory 0.936 0.796 – 1.1 0.423 176 1757 all phecode
512 Other symptoms of respiratory system Respiratory 1.07 1.05 – 1.09 1.03e-10 18621 28154 all phecode
512.1 Wheezing Respiratory 1.19 1.12 – 1.26 3.47e-09 1409 13516 all phecode
512.2 Painful respiration Respiratory 1.04 0.998 – 1.09 0.0586 2309 21263 all phecode
512.3 Abnormal chest sounds Respiratory 1.01 0.891 – 1.14 0.897 291 2845 all phecode
512.7 Shortness of breath Respiratory 1.12 1.09 – 1.15 9.45e-20 10034 28081 all phecode
512.8 Cough Respiratory 1.05 1.03 – 1.08 3.75e-05 9501 28148 all phecode
512.9 Other dyspnea Respiratory 1.1 1.07 – 1.12 1.51e-14 10804 28104 all phecode
513 Respiratory abnormalities Respiratory 1.11 1.08 – 1.13 1.45e-19 12932 33822 all phecode
513.3 Hypoventilation Respiratory 1.17 1.09 – 1.26 2.03e-05 880 8646 all phecode
513.31 Apnea Respiratory 1.1 0.998 – 1.22 0.0545 462 4607 all phecode
513.32 Orthopnea Respiratory 1.13 0.979 – 1.3 0.0951 220 2160 all phecode
513.4 Hyperventilation Respiratory 1.24 1.13 – 1.37 1.15e-05 515 5124 all phecode
513.8 Disorders of diaphragm Respiratory 1.05 0.913 – 1.2 0.512 258 2557 all phecode
514 Abnormal findings examination of lungs Respiratory 1.03 0.995 – 1.06 0.0954 5365 34834 all phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 0.936 0.818 – 1.07 0.331 258 2580 all phecode
514.2 Solitary pulmonary nodule Respiratory 1.02 0.984 – 1.07 0.252 3018 27338 all phecode
516 Abnormal sputum Respiratory 1.13 1.04 – 1.22 0.00334 735 7332 all phecode
516.1 Hemoptysis Respiratory 1.14 1.04 – 1.24 0.00342 611 6080 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.05 1.03 – 1.08 2e-04 6458 39057 all phecode
519.1 Tracheostomy complications Respiratory 1.25 1.08 – 1.45 0.00253 214 2136 all phecode
519.2 Respiratory complications Respiratory 1.05 0.947 – 1.16 0.364 445 4430 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.02 0.964 – 1.07 0.526 1588 15787 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.06 1.03 – 1.1 0.000344 4706 34489 all phecode
520 Disorders of tooth development Digestive 1.01 0.904 – 1.13 0.874 369 3690 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.12 0.944 – 1.32 0.199 165 1642 all phecode
520.2 Disturbances in tooth eruption Digestive 0.977 0.849 – 1.13 0.75 218 2172 all phecode
521 Diseases of hard tissues of teeth Digestive 1.17 1.09 – 1.26 1.23e-05 898 8954 all phecode
521.1 Dental caries Digestive 1.18 1.1 – 1.27 1.04e-05 837 8349 all phecode
521.2 Dental abrasion, erosion and attrition Digestive 1.08 0.812 – 1.45 0.582 52 510 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.2 1.09 – 1.31 0.000124 535 5340 all phecode
522.5 Periapical abscess Digestive 1.22 1.1 – 1.34 0.000111 459 4583 all phecode
523 Gingival and periodontal diseases Digestive 1.13 1.05 – 1.23 0.00182 718 7180 all phecode
523.1 Gingivitis Digestive 1.08 0.901 – 1.29 0.415 142 1418 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.19 1.07 – 1.33 0.00189 364 3636 all phecode
523.31 Acute periodontitis Digestive 1.17 1.04 – 1.32 0.00837 311 3109 all phecode
523.32 Chronic periodontitis Digestive 1.23 1.01 – 1.49 0.0388 122 1204 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.839 0.749 – 0.941 0.00261 363 3630 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.858 0.745 – 0.989 0.0347 220 2200 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.19 1.11 – 1.27 2.83e-07 1039 10382 all phecode
525.1 Loss of teeth or edentulism Digestive 1.13 1.02 – 1.27 0.026 374 3731 all phecode
526 Diseases of the jaws Digestive 0.946 0.907 – 0.986 0.00908 2680 26455 all phecode
526.1 Cysts of the jaws Digestive 0.916 0.799 – 1.05 0.209 247 2470 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.795 0.691 – 0.915 0.0014 241 2383 all phecode
526.4 Temporomandibular joint disorders Digestive 0.918 0.868 – 0.971 0.00287 1504 15025 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.927 0.871 – 0.988 0.0187 1187 11858 all phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 0.869 0.802 – 0.941 0.000562 741 7400 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.992 0.876 – 1.12 0.906 287 2864 all phecode
526.8 Exostosis of jaw Digestive 1.01 0.749 – 1.35 0.969 53 521 all phecode
526.9 Jaw disease NOS Digestive 0.952 0.863 – 1.05 0.32 487 4867 all phecode
527 Diseases of the salivary glands Digestive 1.04 0.984 – 1.09 0.176 1781 17771 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.01 0.766 – 1.32 0.971 58 579 all phecode
527.2 Sialoadenitis Digestive 1.07 0.955 – 1.19 0.254 394 3936 all phecode
527.7 Disturbance of salivary secretion Digestive 1 0.936 – 1.08 0.92 952 9481 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.13 0.988 – 1.3 0.0733 254 2540 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.98 0.94 – 1.02 0.351 2643 26197 all phecode
528.1 Stomatitis and mucositis Digestive 0.974 0.896 – 1.06 0.543 668 6657 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.09 0.939 – 1.27 0.255 211 2110 all phecode
528.12 Oral aphthae Digestive 0.974 0.842 – 1.13 0.721 215 2137 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.24 1.08 – 1.42 0.00226 235 2338 all phecode
528.4 Cysts of oral soft tissues Digestive 0.888 0.733 – 1.08 0.224 124 1229 all phecode
528.41 Cyst of the salivary gland Digestive 1 0.786 – 1.28 0.99 77 760 all phecode
528.5 Diseases of lips Digestive 1.01 0.912 – 1.12 0.858 462 4602 all phecode
528.6 Leukoplakia of oral mucosa Digestive 0.998 0.829 – 1.2 0.981 137 1370 all phecode
528.7 Sialolithiasis Digestive 1.09 0.919 – 1.29 0.324 163 1623 all phecode
529 Diseases and other conditions of the tongue Digestive 1.08 0.997 – 1.18 0.0586 690 6878 all phecode
529.1 Glossitis Digestive 1.1 0.905 – 1.33 0.348 129 1281 all phecode
529.6 Glossodynia Digestive 1.06 0.9 – 1.26 0.469 168 1652 all phecode
530 Diseases of esophagus Digestive 1.1 1.08 – 1.12 8.13e-20 17081 27931 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.1 1.08 – 1.12 6.73e-20 16572 27931 all phecode
530.11 GERD Digestive 1.1 1.08 – 1.13 1.98e-20 16143 27929 all phecode
530.12 Ulcer of esophagus Digestive 1.05 0.941 – 1.17 0.389 400 3983 all phecode
530.13 Barrett's esophagus Digestive 1.17 1.09 – 1.27 5.87e-05 762 7584 all phecode
530.14 Reflux esophagitis Digestive 1.06 1.01 – 1.12 0.014 1900 17495 all phecode
530.15 Eosinophilic esophagitis Digestive 1.09 0.938 – 1.26 0.272 221 2210 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.08 0.995 – 1.18 0.0657 651 6473 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.1 1.02 – 1.18 0.011 911 8971 all phecode
530.5 Disorders of esophageal motility Digestive 1.11 1.01 – 1.22 0.0268 548 5432 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.935 0.777 – 1.13 0.48 129 1265 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.14 0.903 – 1.43 0.278 82 812 all phecode
530.9 Heartburn Digestive 1.08 1.03 – 1.15 0.00456 1519 14928 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.09 1.04 – 1.14 0.000661 2073 20617 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.08 0.966 – 1.2 0.183 391 3883 all phecode
531.2 Gastric ulcer Digestive 1.12 1.05 – 1.19 0.000279 1201 11970 all phecode
531.3 Duodenal ulcer Digestive 1.03 0.934 – 1.14 0.54 467 4640 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.05 0.972 – 1.13 0.214 804 8018 all phecode
531.5 Gastrojejunal ulcer Digestive 1.18 0.992 – 1.41 0.0609 150 1500 all phecode
532 Dysphagia Digestive 1.1 1.07 – 1.13 1.98e-09 5585 26852 all phecode
535 Gastritis and duodenitis Digestive 1.08 1.03 – 1.12 0.000539 2799 27335 all phecode
535.1 Acute gastritis Digestive 1.13 1.06 – 1.2 0.000152 1178 11750 all phecode
535.2 Atrophic gastritis Digestive 1.03 0.912 – 1.15 0.679 344 3413 all phecode
535.6 Duodenitis Digestive 1.04 0.926 – 1.17 0.497 334 3337 all phecode
535.8 Other specified gastritis Digestive 1.01 0.925 – 1.1 0.853 638 6354 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.03 0.968 – 1.09 0.355 1255 12511 all phecode
536 Disorders of function of stomach Digestive 1.04 0.999 – 1.08 0.0582 2911 27685 all phecode
536.3 Gastroparesis Digestive 1.08 0.996 – 1.17 0.0613 706 6901 all phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.1 0.99 – 1.22 0.076 407 4059 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.02 0.977 – 1.07 0.322 2150 21094 all phecode
537 Other disorders of stomach and duodenum Digestive 1.08 1.04 – 1.13 3.63e-05 3183 30048 all phecode
537.1 Lesions of stomach and duodenum Digestive 1.16 0.984 – 1.36 0.0774 173 1725 all phecode
539 Bariatric surgery Digestive 1.71 1.61 – 1.81 3.22e-74 1509 15074 all phecode
540 Appendiceal conditions Digestive 0.971 0.88 – 1.07 0.55 495 4948 all phecode
540.1 Appendicitis Digestive 0.949 0.853 – 1.05 0.331 425 4239 all phecode
540.11 Acute appendicitis Digestive 0.913 0.813 – 1.03 0.127 353 3511 all phecode
550 Abdominal hernia Digestive 1.05 1.02 – 1.07 0.00171 6768 37731 all phecode
550.1 Inguinal hernia Digestive 0.835 0.793 – 0.88 1.19e-11 1744 16488 all phecode
550.2 Diaphragmatic hernia Digestive 1.05 1.01 – 1.09 0.0225 2817 25849 all phecode
550.3 Femoral hernia Digestive 0.833 0.686 – 1.01 0.0659 131 1291 all phecode
550.4 Umbilical hernia Digestive 1.1 1.04 – 1.17 0.00114 1313 13110 all phecode
550.5 Ventral hernia Digestive 1.18 1.12 – 1.23 4e-12 2241 22163 all phecode
550.6 Incisional hernia Digestive 1.16 1.09 – 1.23 8.03e-07 1313 13111 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.06 1.01 – 1.12 0.0276 1536 15153 all phecode
555.1 Regional enteritis Digestive 1.11 1.03 – 1.19 0.00533 919 9095 all phecode
555.2 Ulcerative colitis Digestive 0.996 0.928 – 1.07 0.904 937 9315 all phecode
555.21 Ulcerative colitis (chronic) Digestive 0.917 0.836 – 1.01 0.0676 537 5315 all phecode
556 Ulceration of the lower GI tract Digestive 1.08 0.989 – 1.18 0.0878 632 6267 all phecode
556.1 Ulceration of intestine Digestive 1.08 0.982 – 1.18 0.114 551 5451 all phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 1.01 0.874 – 1.17 0.869 214 2093 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.2 1.14 – 1.27 6.18e-12 1716 16490 all phecode
557.1 Celiac disease Digestive 0.946 0.851 – 1.05 0.296 421 4026 all phecode
558 Noninfectious gastroenteritis Digestive 1.05 1.02 – 1.09 0.00608 3458 26408 all phecode
559 Ileostomy status Digestive 1.05 0.977 – 1.12 0.192 957 9565 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.07 1.02 – 1.11 0.00187 3004 24851 all phecode
560.1 Paralytic ileus Digestive 1.05 0.996 – 1.11 0.0709 1627 15714 all phecode
560.2 Impaction of intestine Digestive 1.06 0.949 – 1.19 0.301 387 3779 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.939 0.822 – 1.07 0.359 266 2647 all phecode
560.4 Other intestinal obstruction Digestive 1.08 1.02 – 1.14 0.00493 1651 16170 all phecode
561 Symptoms involving digestive system Digestive 1.02 0.976 – 1.06 0.394 2608 21766 all phecode
562 Diverticulosis and diverticulitis Digestive 1.03 0.998 – 1.06 0.0716 6295 23431 all phecode
562.1 Diverticulosis Digestive 1.03 0.997 – 1.06 0.0829 6246 23383 all phecode
562.2 Diverticulitis Digestive 1.03 0.972 – 1.08 0.35 1611 15162 all phecode
564 Functional digestive disorders Digestive 1.05 1.03 – 1.08 2.48e-05 11411 28676 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.03 0.992 – 1.07 0.124 3457 22266 all phecode
564.9 Personal history of diseases of digestive system Digestive 1.07 1.03 – 1.11 0.000748 3074 25861 all phecode
565 Anal and rectal conditions Digestive 0.974 0.938 – 1.01 0.175 3355 30757 all phecode
565.1 Anal and rectal polyp Digestive 0.994 0.937 – 1.06 0.854 1305 12649 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.1 1.04 – 1.17 0.00137 1364 13616 all phecode
568 Other disorders of peritoneum Digestive 1.12 1.06 – 1.18 1.67e-05 1705 17038 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.14 1.07 – 1.21 3.28e-05 1247 12468 all phecode
569 Other disorders of intestine Digestive 1.05 1.02 – 1.08 0.000154 8079 35231 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.06 0.942 – 1.2 0.327 326 3260 all phecode
569.2 Gastrointestinal complications Digestive 1.17 1.1 – 1.24 1.77e-07 1395 13933 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.11 1.08 – 1.15 1.41e-10 4610 32562 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.12 1.08 – 1.16 3.73e-11 4342 32234 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.11 1.03 – 1.18 0.00376 1018 10095 all phecode
571.6 Primary biliary cirrhosis Digestive 0.931 0.796 – 1.09 0.373 179 1790 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.07 1 – 1.15 0.0476 950 9498 all phecode
571.81 Portal hypertension Digestive 1.05 0.964 – 1.15 0.244 573 5730 all phecode
572 Ascites (non malignant) Digestive 1.05 1.01 – 1.1 0.0223 2278 22675 all phecode
573 Other disorders of liver Digestive 1.07 1.04 – 1.1 1.35e-05 5599 33620 all phecode
573.1 Chronic passive congestion of liver Digestive 1.35 1.13 – 1.63 0.00126 136 1359 all phecode
573.2 Liver replaced by transplant Digestive 1.04 0.914 – 1.18 0.575 292 2920 all phecode
573.3 Hepatomegaly Digestive 1.18 1.06 – 1.3 0.00135 470 4700 all phecode
573.4 Acute and subacute necrosis of liver Digestive 0.988 0.874 – 1.12 0.845 316 3149 all phecode
573.5 Jaundice (not of newborn) Digestive 1.03 0.96 – 1.1 0.408 958 9496 all phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.02 0.982 – 1.07 0.269 2756 26470 all phecode
573.7 Abnormal results of function study of liver Digestive 1.02 0.981 – 1.06 0.302 3018 27774 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.04 1 – 1.07 0.0308 4679 33866 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.1 1.06 – 1.15 5.03e-07 3177 30809 all phecode
574.1 Cholelithiasis Digestive 1.1 1.06 – 1.15 2.09e-06 2924 28874 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.14 1.02 – 1.29 0.0244 342 3412 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.07 0.976 – 1.17 0.149 553 5501 all phecode
574.2 Calculus of bile duct Digestive 1.04 0.968 – 1.12 0.265 852 8503 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.13 1.05 – 1.22 0.00128 822 8181 all phecode
575 Other biliary tract disease Digestive 1.02 0.976 – 1.07 0.351 2266 22555 all phecode
575.1 Cholangitis Digestive 0.981 0.876 – 1.1 0.748 354 3530 all phecode
575.2 Obstruction of bile duct Digestive 1.08 0.993 – 1.18 0.0708 621 6201 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.926 0.8 – 1.07 0.309 207 2063 all phecode
575.7 Other disorders of gallbladder Digestive 0.985 0.918 – 1.06 0.677 939 9382 all phecode
575.8 Other disorders of biliary tract Digestive 1.05 0.984 – 1.12 0.139 1154 11523 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1 0.876 – 1.14 0.983 260 2600 all phecode
577 Diseases of pancreas Digestive 1.04 0.997 – 1.09 0.068 2225 22106 all phecode
577.1 Acute pancreatitis Digestive 1.1 1.03 – 1.17 0.00234 1212 12110 all phecode
577.2 Chronic pancreatitis Digestive 1.16 1.05 – 1.28 0.00357 495 4950 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1 0.916 – 1.1 0.922 570 5601 all phecode
578 Gastrointestinal hemorrhage Digestive 1.03 0.996 – 1.06 0.0902 4554 37045 all phecode
578.1 Hematemesis Digestive 1.16 1.05 – 1.28 0.00285 485 4842 all phecode
578.2 Blood in stool Digestive 1.05 1.01 – 1.1 0.0154 2743 26554 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.01 0.962 – 1.05 0.763 2210 21750 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.06 1.01 – 1.12 0.0274 1562 15345 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.1 1.06 – 1.13 4.3e-08 4431 34209 all phecode
579.2 Splenomegaly Digestive 1.16 1.07 – 1.25 4e-04 730 7262 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.05 0.992 – 1.11 0.0907 1410 13877 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.22 1.16 – 1.29 3.61e-14 1881 15516 all phecode
580.1 Glomerulonephritis Genitourinary 1.23 1.1 – 1.37 0.000298 401 3992 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.18 0.991 – 1.41 0.0626 146 1440 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.46 1.19 – 1.79 0.000317 114 1128 all phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.09 0.826 – 1.43 0.557 61 600 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.3 1.14 – 1.49 9.17e-05 277 2760 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.17 1.02 – 1.35 0.0291 221 2193 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.24 1.17 – 1.31 7.5e-13 1502 11930 all phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.3 1.21 – 1.4 8.63e-13 992 7228 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.18 1.08 – 1.28 0.000116 683 6612 all phecode
580.4 Renal sclerosis, NOS Genitourinary 1.21 1.07 – 1.37 0.00168 340 3400 all phecode
585 Renal failure Genitourinary 1.17 1.14 – 1.2 5.82e-28 7470 32340 all phecode
585.1 Acute renal failure Genitourinary 1.17 1.13 – 1.22 1.33e-19 4265 27230 all phecode
585.2 Renal failure NOS Genitourinary 1.2 1.11 – 1.29 2.71e-06 832 8162 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.2 1.16 – 1.23 5.37e-29 5580 29470 all phecode
585.31 Renal dialysis Genitourinary 1.19 1.1 – 1.29 1.78e-05 747 7423 all phecode
585.32 End stage renal disease Genitourinary 1.27 1.18 – 1.36 1.27e-11 1007 9783 all phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.22 1.17 – 1.27 1.56e-21 3209 21312 all phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.25 1.17 – 1.34 2.68e-10 977 9190 all phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.2 1.13 – 1.28 6.42e-09 1227 11191 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.11 1.08 – 1.14 1.45e-13 7628 34189 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.14 1.01 – 1.28 0.0311 349 3480 all phecode
586.11 Small kidney Genitourinary 1.17 1.01 – 1.36 0.0349 210 2093 all phecode
586.12 Vesicoureteral reflux Genitourinary 1.07 0.886 – 1.28 0.495 136 1360 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.03 0.973 – 1.09 0.301 1381 12912 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.21 1.03 – 1.41 0.0168 187 1862 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1 0.955 – 1.06 0.865 1821 17115 all phecode
587 Kidney replaced by transpant Genitourinary 1.11 1.03 – 1.2 0.00688 819 8134 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.24 1.16 – 1.33 2.1e-09 976 9389 all phecode
588.1 Renal osteodystrophy Genitourinary 1.15 1.01 – 1.31 0.0364 290 2900 all phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.24 1.15 – 1.35 1.22e-07 755 7275 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.16 1.09 – 1.25 1.79e-05 1007 9834 all phecode
590 Pyelonephritis Genitourinary 1.13 1.07 – 1.2 2.39e-05 1461 14350 all phecode
591 Urinary tract infection Genitourinary 1.03 1 – 1.05 0.0229 9873 32513 all phecode
592 Cystitis and urethritis Genitourinary 1.01 0.974 – 1.06 0.508 3038 24207 all phecode
592.1 Cystitis Genitourinary 1.02 0.977 – 1.06 0.389 2880 23279 all phecode
592.11 Acute cystitis Genitourinary 1.02 0.969 – 1.08 0.431 1783 16452 all phecode
592.12 Chronic cystitis Genitourinary 0.934 0.811 – 1.08 0.34 239 2343 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.95 0.856 – 1.06 0.34 431 4310 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.946 0.813 – 1.1 0.476 210 2093 all phecode
593 Hematuria Genitourinary 1.04 1.01 – 1.08 0.0135 4859 32063 all phecode
593.1 Gross hematuria Genitourinary 1.07 1.01 – 1.12 0.0229 1585 14824 all phecode
593.2 Microscopic hematuria Genitourinary 1.02 0.952 – 1.09 0.59 1049 10301 all phecode
594 Urinary calculus Genitourinary 1.08 1.05 – 1.11 1.3e-07 6707 38209 all phecode
594.1 Calculus of kidney Genitourinary 1.07 1.04 – 1.11 5.47e-07 6273 38051 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.1 0.983 – 1.23 0.0983 366 3638 all phecode
594.3 Calculus of ureter Genitourinary 1.03 0.975 – 1.1 0.262 1361 13561 all phecode
594.8 Renal colic Genitourinary 1.1 0.981 – 1.23 0.102 356 3560 all phecode
595 Hydronephrosis Genitourinary 1.06 1 – 1.12 0.0342 1670 16658 all phecode
596 Other disorders of bladder Genitourinary 0.995 0.956 – 1.03 0.793 3074 28020 all phecode
596.1 Bladder neck obstruction Genitourinary 1.02 0.912 – 1.13 0.78 400 3942 all phecode
596.5 Functional disorders of bladder Genitourinary 0.983 0.933 – 1.04 0.526 1719 17049 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.967 0.909 – 1.03 0.291 1211 11998 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.947 0.871 – 1.03 0.198 661 6537 all phecode
597.2 Urinary complications NEC Genitourinary 1.01 0.944 – 1.08 0.788 1049 10479 all phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.02 0.872 – 1.19 0.805 189 1873 all phecode
598 Abnormal findings on examination of urine Genitourinary 0.999 0.829 – 1.2 0.992 138 1356 all phecode
598.4 Other cells and casts in urine Genitourinary 0.994 0.814 – 1.21 0.951 122 1192 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.989 – 1.03 0.322 14168 30681 all phecode
599.1 Urinary obstruction Genitourinary 0.874 0.807 – 0.948 0.00109 728 6861 all phecode
599.2 Retention of urine Genitourinary 1.01 0.976 – 1.04 0.606 5034 28305 all phecode
599.3 Dysuria Genitourinary 1 0.969 – 1.04 0.909 4397 27849 all phecode
599.4 Urinary incontinence Genitourinary 1.03 1 – 1.06 0.0495 5599 26960 all phecode
599.5 Frequency of urination and polyuria Genitourinary 0.973 0.943 – 1 0.079 5498 28723 all phecode
599.6 Oliguria and anuria Genitourinary 1.13 1.03 – 1.23 0.00937 599 5902 all phecode
599.7 Urethral discharge Genitourinary 1.15 0.946 – 1.39 0.162 118 1175 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1 0.969 – 1.03 0.991 5446 27963 all phecode
599.9 Other abnormality of urination Genitourinary 0.972 0.934 – 1.01 0.169 3041 24877 all phecode
600 Hyperplasia of prostate Genitourinary 0.968 0.93 – 1.01 0.114 4063 11364 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.99 0.926 – 1.06 0.77 1044 9665 all phecode
601.1 Prostatitis Genitourinary 0.889 0.806 – 0.982 0.0199 477 4596 all phecode
601.11 Acute prostatitis Genitourinary 0.976 0.804 – 1.18 0.807 124 1200 all phecode
601.12 Chronic prostatitis Genitourinary 0.934 0.748 – 1.17 0.544 95 943 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.07 0.956 – 1.19 0.255 389 3822 all phecode
601.4 Balanoposthitis Genitourinary 1.03 0.849 – 1.25 0.762 127 1224 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.18 0.994 – 1.4 0.058 161 1591 all phecode
602 Other disorders of prostate Genitourinary 0.926 0.825 – 1.04 0.188 361 3399 all phecode
602.3 Dysplasia of prostate Genitourinary 1.06 0.825 – 1.37 0.644 77 730 all phecode
603 Other disorders of testis Genitourinary 0.991 0.896 – 1.1 0.858 440 4354 all phecode
603.1 Hydrocele Genitourinary 0.988 0.875 – 1.12 0.851 293 2882 all phecode
603.2 Spermatocele Genitourinary 0.898 0.757 – 1.07 0.219 156 1539 all phecode
604 Disorders of penis Genitourinary 1 0.923 – 1.09 0.971 685 6748 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.27 1.08 – 1.51 0.00517 155 1540 all phecode
604.3 Peyronie's disease Genitourinary 0.94 0.813 – 1.09 0.409 215 2132 all phecode
605 Erectile dysfunction [ED] Genitourinary 0.971 0.934 – 1.01 0.142 3776 12700 all phecode
608 Other disorders of male genital organs Genitourinary 0.96 0.91 – 1.01 0.139 1645 13758 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.839 0.756 – 0.93 0.000851 424 4196 all phecode
609.1 Infertility, male Genitourinary 0.825 0.731 – 0.932 0.00191 302 2992 all phecode
609.11 Azoospermia and oligospermia Genitourinary 1.06 0.847 – 1.32 0.628 95 950 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.817 0.688 – 0.969 0.0205 154 1519 all phecode
610 Benign mammary dysplasias Genitourinary 0.924 0.889 – 0.96 5e-05 3683 16548 all phecode
610.1 Cystic mastopathy Genitourinary 0.932 0.882 – 0.984 0.0117 1633 14191 all phecode
610.2 Fibroadenosis of breast Genitourinary 0.775 0.593 – 1.01 0.0628 60 600 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.903 0.865 – 0.943 3.18e-06 2837 16430 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.918 0.862 – 0.976 0.00665 1269 12191 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.919 0.891 – 0.948 1.45e-07 6067 18690 all phecode
611.1 Abnormal mammogram Genitourinary 0.905 0.874 – 0.936 1.16e-08 4980 16120 all phecode
611.11 Mammographic microcalcification Genitourinary 0.842 0.788 – 0.901 4.55e-07 1122 10394 all phecode
611.3 Lump or mass in breast Genitourinary 0.913 0.879 – 0.949 4e-06 3549 18572 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.965 0.902 – 1.03 0.306 1051 10425 all phecode
612.1 Galactorrhea Genitourinary 0.969 0.808 – 1.16 0.729 139 1390 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.01 0.937 – 1.09 0.767 800 7962 all phecode
612.3 Congenital anomalies of breast Genitourinary 0.662 0.516 – 0.85 0.00119 83 810 all phecode
613 Other nonmalignant breast conditions Genitourinary 0.961 0.927 – 0.997 0.0327 3897 22072 all phecode
613.1 Inflammatory disease of breast Genitourinary 0.96 0.878 – 1.05 0.363 593 5874 all phecode
613.5 Mastodynia Genitourinary 0.961 0.911 – 1.01 0.152 1675 16203 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.905 0.84 – 0.974 0.00792 883 8754 all phecode
613.8 Other specified disorders of breast Genitourinary 0.891 0.829 – 0.958 0.00167 932 9248 all phecode
613.9 Breast disorder NOS Genitourinary 0.95 0.897 – 1.01 0.0811 1465 14174 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.997 0.961 – 1.03 0.877 3715 19647 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.01 0.895 – 1.13 0.911 337 3370 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1 0.909 – 1.11 0.957 478 4773 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.1 0.885 – 1.37 0.388 94 933 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.917 0.783 – 1.07 0.286 186 1842 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.932 0.814 – 1.07 0.313 246 2460 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.09 0.922 – 1.29 0.308 165 1639 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.99 0.952 – 1.03 0.636 3180 19539 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.02 0.889 – 1.16 0.814 264 2640 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.972 0.931 – 1.01 0.186 2732 18924 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.22 1.01 – 1.47 0.041 132 1311 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.22 1.05 – 1.41 0.00815 225 2244 all phecode
615 Endometriosis Genitourinary 0.991 0.938 – 1.05 0.75 1585 14666 all phecode
618 Genital prolapse Genitourinary 0.979 0.932 – 1.03 0.383 2079 17915 all phecode
618.1 Prolapse of vaginal walls Genitourinary 0.934 0.881 – 0.99 0.0215 1408 13456 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.938 0.854 – 1.03 0.184 542 5390 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.956 0.844 – 1.08 0.485 317 3162 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.06 0.952 – 1.17 0.304 441 4394 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.992 0.962 – 1.02 0.638 5728 18687 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.997 0.937 – 1.06 0.919 1233 12082 all phecode
619.2 Disorders of uterus, NEC Genitourinary 0.93 0.85 – 1.02 0.113 591 5897 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.935 0.848 – 1.03 0.182 483 4823 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.999 0.956 – 1.04 0.979 2525 18404 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.04 0.977 – 1.11 0.218 1189 11717 all phecode
620 Dysplasia of female genital organs Genitourinary 1.05 0.944 – 1.17 0.362 395 3950 all phecode
620.1 Dysplasia of cervix Genitourinary 1.03 0.882 – 1.21 0.684 178 1780 all phecode
621 Endometrial hyperplasia Genitourinary 1.11 0.998 – 1.24 0.0543 437 4370 all phecode
622 Polyp of female genital organs Genitourinary 0.952 0.899 – 1.01 0.0957 1449 14264 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.978 0.916 – 1.04 0.496 1132 11189 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.886 0.798 – 0.983 0.0229 445 4444 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.04 0.966 – 1.12 0.285 824 8165 all phecode
624 Symptoms involving female genital tract Genitourinary 0.985 0.928 – 1.04 0.614 1348 12518 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.94 0.811 – 1.09 0.409 216 2155 all phecode
624.2 Atrophy of female genital tract Genitourinary 1.22 0.916 – 1.61 0.176 64 615 all phecode
624.9 stress incontinence, female Genitourinary 1.01 0.964 – 1.07 0.581 1935 15408 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.972 0.941 – 1 0.077 5653 17303 all phecode
625.1 Dyspareunia Genitourinary 0.932 0.876 – 0.991 0.0239 1267 12474 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.999 0.967 – 1.03 0.962 5940 15585 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.993 0.957 – 1.03 0.703 4315 14604 all phecode
626.11 Absent or infrequent menstruation Genitourinary 1.03 0.961 – 1.1 0.428 1062 8531 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.01 0.962 – 1.06 0.666 2097 11991 all phecode
626.13 Irregular menstrual cycle Genitourinary 1 0.951 – 1.05 0.988 1957 12265 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.954 0.889 – 1.02 0.182 970 8996 all phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.998 0.896 – 1.11 0.974 394 3789 all phecode
626.2 Dysmenorrhea Genitourinary 1.03 0.967 – 1.09 0.385 1373 9857 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.983 0.872 – 1.11 0.774 336 3308 all phecode
626.8 Infertility, female Genitourinary 0.971 0.9 – 1.05 0.447 817 6741 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.944 0.91 – 0.978 0.0015 4560 14557 all phecode
627.1 Postmenopausal bleeding Genitourinary 0.985 0.922 – 1.05 0.662 1146 10338 all phecode
627.2 Symptomatic menopause Genitourinary 0.927 0.888 – 0.967 0.000469 3017 13763 all phecode
627.21 Symptomatic artificial menopause Genitourinary 0.878 0.734 – 1.05 0.154 152 1514 all phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.752 0.668 – 0.848 2.84e-06 356 3513 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.894 0.833 – 0.959 0.00183 997 9484 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.962 0.858 – 1.08 0.509 361 3580 all phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.846 0.748 – 0.957 0.00796 309 3082 all phecode
628 Ovarian cyst Genitourinary 1 0.955 – 1.06 0.856 1945 13838 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1 0.93 – 1.08 0.965 826 8047 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.968 0.85 – 1.1 0.628 273 2715 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.01 0.827 – 1.23 0.921 117 1170 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.893 0.816 – 0.977 0.0138 563 5309 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.872 0.779 – 0.976 0.0169 370 3629 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.895 0.789 – 1.01 0.0839 288 2850 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.949 0.888 – 1.01 0.12 1080 7870 all phecode
636.1 Threatened premature labor Pregnancy Complications 0.946 0.848 – 1.06 0.319 380 3799 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.934 0.823 – 1.06 0.29 288 2868 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.969 0.876 – 1.07 0.545 441 4365 all phecode
636.8 Cervical incompetence Pregnancy Complications 1.08 0.851 – 1.37 0.529 77 770 all phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.13 0.894 – 1.42 0.311 85 850 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.03 0.94 – 1.12 0.549 585 5725 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.04 0.916 – 1.17 0.58 302 3013 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.07 0.935 – 1.22 0.333 252 2506 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.01 0.837 – 1.22 0.904 119 1190 all phecode
644 Anemia during pregnancy Pregnancy Complications 1.01 0.871 – 1.16 0.936 224 2224 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.01 0.934 – 1.08 0.882 855 6531 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.959 0.831 – 1.11 0.568 211 2093 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.02 0.889 – 1.18 0.745 222 2213 all phecode
647.3 Major puerperal infection Pregnancy Complications 1.04 0.803 – 1.35 0.762 65 650 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.982 0.923 – 1.05 0.569 1275 8010 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.03 0.947 – 1.12 0.484 649 5687 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.995 0.911 – 1.09 0.914 587 5463 all phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.985 0.846 – 1.15 0.846 207 2055 all phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 0.912 0.786 – 1.06 0.229 204 2040 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.949 0.898 – 1 0.0613 1624 10064 all phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 0.963 0.883 – 1.05 0.39 616 5533 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.992 0.923 – 1.07 0.825 898 7014 all phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 0.917 0.71 – 1.19 0.509 66 660 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.949 0.882 – 1.02 0.158 887 6802 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.09 0.951 – 1.26 0.208 236 2351 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.09 0.919 – 1.29 0.325 158 1580 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.859 0.735 – 1 0.0567 184 1814 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.13 1.1 – 1.17 6.82e-19 6500 38394 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.04 0.975 – 1.1 0.248 1256 11462 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.12 1.04 – 1.2 0.00129 1007 9981 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.18 1.12 – 1.23 1.89e-11 2123 19952 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.18 1.13 – 1.24 6.09e-13 2252 20944 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.19 1.13 – 1.25 6.14e-11 1820 16893 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.22 1.16 – 1.29 9.15e-13 1572 15588 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.08 1.04 – 1.14 5e-04 2257 21750 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.11 1.02 – 1.22 0.0205 558 5504 all phecode
686.2 Impetigo Dermatologic 1.09 0.982 – 1.22 0.105 414 4117 all phecode
686.3 Pilonidal cyst Dermatologic 1.08 0.912 – 1.28 0.376 160 1594 all phecode
686.4 Pyogenic granuloma Dermatologic 1.03 0.871 – 1.22 0.713 158 1570 all phecode
686.5 Pyoderma Dermatologic 1.21 0.913 – 1.59 0.188 63 630 all phecode
687 Symptoms affecting skin Dermatologic 0.987 0.936 – 1.04 0.619 1690 16343 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.997 0.97 – 1.02 0.841 7007 34623 all phecode
687.3 Changes in skin texture Dermatologic 1.11 0.998 – 1.23 0.0544 415 4121 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.04 1.01 – 1.07 0.00694 6375 34216 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.944 0.921 – 0.967 3.64e-06 9311 37335 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.909 0.881 – 0.939 3.91e-09 5184 31581 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.909 0.881 – 0.939 4.15e-09 5174 31553 all phecode
691 Congenital anomalies of skin Dermatologic 0.992 0.904 – 1.09 0.871 541 5337 all phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 1.03 0.791 – 1.33 0.84 62 613 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.931 0.885 – 0.979 0.00525 1861 17936 all phecode
694.1 Vitiligo Dermatologic 1.1 0.922 – 1.32 0.281 137 1347 all phecode
694.2 Other dyschromia Dermatologic 0.916 0.869 – 0.966 0.00129 1674 16183 all phecode
694.3 Vascular disorders of skin Dermatologic 1.16 0.907 – 1.47 0.242 82 819 all phecode
695 Erythematous conditions Dermatologic 1.02 0.987 – 1.06 0.231 4120 30247 all phecode
695.1 Toxic erythema Dermatologic 1.13 0.884 – 1.45 0.324 70 688 all phecode
695.2 Bullous dermatoses Dermatologic 1.17 0.922 – 1.49 0.197 85 805 all phecode
695.3 Rosacea Dermatologic 0.917 0.871 – 0.965 0.000968 1816 17663 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.07 0.988 – 1.17 0.0941 672 6686 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.14 0.997 – 1.31 0.0553 247 2437 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.06 0.975 – 1.16 0.168 637 6337 all phecode
695.7 Prurigo and Lichen Dermatologic 0.978 0.895 – 1.07 0.619 605 5986 all phecode
695.8 Other specified erythematous conditions Dermatologic 1.12 1.03 – 1.2 0.00518 812 7980 all phecode
695.81 Erythema nodosum Dermatologic 0.909 0.682 – 1.21 0.518 55 550 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.15 1.06 – 1.25 0.000739 679 6756 all phecode
696 Psoriasis and related disorders Dermatologic 1.05 0.987 – 1.11 0.126 1401 13832 all phecode
696.3 Pityriasis Dermatologic 0.913 0.734 – 1.14 0.412 92 904 all phecode
696.4 Psoriasis Dermatologic 1.07 1.01 – 1.13 0.032 1311 12976 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.06 0.992 – 1.12 0.0866 1200 11867 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.03 0.905 – 1.17 0.644 282 2810 all phecode
697 Sarcoidosis Dermatologic 1.06 0.94 – 1.19 0.36 333 3330 all phecode
698 Pruritus and related conditions Dermatologic 0.998 0.953 – 1.04 0.931 2254 21889 all phecode
700 Corns and callosities Dermatologic 1.06 0.994 – 1.12 0.08 1373 10894 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.997 0.971 – 1.02 0.794 7651 38050 all phecode
701.1 Keratoderma, acquired Dermatologic 1.05 0.961 – 1.15 0.27 567 5524 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.926 0.884 – 0.97 0.00124 2184 21550 all phecode
701.3 Circumscribed scleroderma Dermatologic 0.993 0.906 – 1.09 0.879 571 5660 all phecode
701.4 Keloid scar Dermatologic 1 0.917 – 1.1 0.949 578 5716 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.05 0.94 – 1.16 0.411 400 3982 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.894 0.868 – 0.919 1.05e-14 6956 29525 all phecode
702.1 Actinic keratosis Dermatologic 0.858 0.828 – 0.889 1.68e-17 4171 26529 all phecode
702.2 Seborrheic keratosis Dermatologic 0.886 0.859 – 0.914 2.21e-14 5480 31552 all phecode
702.4 Degenerative skin disorders Dermatologic 1.15 0.912 – 1.44 0.24 86 832 all phecode
703 Diseases of nail, NOS Dermatologic 1.03 0.977 – 1.09 0.258 1650 14562 all phecode
703.1 Ingrowing nail Dermatologic 1.04 0.97 – 1.12 0.263 920 8597 all phecode
704 Diseases of hair and hair follicles Dermatologic 0.956 0.92 – 0.994 0.0243 3118 29542 all phecode
704.1 Alopecia Dermatologic 0.954 0.9 – 1.01 0.112 1408 13871 all phecode
704.11 Alopecia Areata Dermatologic 0.889 0.703 – 1.12 0.325 82 811 all phecode
704.12 Telogen effluvium Dermatologic 0.824 0.626 – 1.08 0.167 63 615 all phecode
704.2 Hirsutism Dermatologic 1.43 1.26 – 1.62 2.7e-08 299 2946 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.947 0.899 – 0.997 0.0393 1752 17189 all phecode
705 Disorders of sweat glands Dermatologic 1.18 1.08 – 1.28 0.000307 603 6012 all phecode
705.1 Dyshidrosis Dermatologic 1.01 0.845 – 1.21 0.905 154 1540 all phecode
705.3 Hidradenitis Dermatologic 1.39 1.21 – 1.6 3.58e-06 245 2440 all phecode
705.8 Hyperhidrosis Dermatologic 1.01 0.947 – 1.08 0.756 1112 10986 all phecode
706 Diseases of sebaceous glands Dermatologic 0.929 0.903 – 0.956 5.56e-07 5995 39748 all phecode
706.1 Acne Dermatologic 0.865 0.829 – 0.903 3.33e-11 2594 22570 all phecode
706.2 Sebaceous cyst Dermatologic 0.949 0.911 – 0.989 0.0127 2814 26819 all phecode
706.3 Seborrhea Dermatologic 0.839 0.635 – 1.11 0.219 59 582 all phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.972 0.922 – 1.03 0.302 1684 15289 all phecode
707 Chronic ulcer of skin Dermatologic 1.16 1.12 – 1.21 5.81e-13 2871 26816 all phecode
707.1 Decubitus ulcer Dermatologic 1.16 1.08 – 1.25 8.18e-05 825 8119 all phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.25 1.17 – 1.33 2.03e-11 1108 9992 all phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1.15 1.09 – 1.21 6.12e-07 1641 16172 all phecode
709 Diffuse diseases of connective tissue Dermatologic 1.04 0.981 – 1.1 0.193 1477 14427 all phecode
709.2 Sicca syndrome Dermatologic 1.05 0.957 – 1.16 0.289 505 4986 all phecode
709.3 Systemic sclerosis Dermatologic 0.867 0.752 – 0.999 0.0481 224 2209 all phecode
709.5 Dermatomyositis Dermatologic 1.18 0.951 – 1.47 0.133 92 892 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.19 0.943 – 1.5 0.144 90 892 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.04 0.966 – 1.12 0.306 917 9089 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.2 1.13 – 1.28 8.35e-09 1254 12103 all phecode
710.1 Osteomyelitis Musculoskeletal 1.2 1.13 – 1.28 1.38e-08 1203 11636 all phecode
710.11 Acute osteomyelitis Musculoskeletal 1.34 1.22 – 1.47 4.1e-10 590 5708 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.24 1.13 – 1.37 6.86e-06 531 5163 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.21 1.14 – 1.3 3.71e-09 1153 11149 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.06 0.949 – 1.18 0.309 410 4099 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.14 1 – 1.3 0.0431 290 2900 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.32 1.11 – 1.56 0.0013 178 1776 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.22 1.08 – 1.37 0.00172 314 3028 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.27 1.09 – 1.49 0.00251 194 1824 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.14 1.08 – 1.19 1.56e-07 2086 18159 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.17 1.11 – 1.24 6.14e-09 1670 15087 all phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.06 0.834 – 1.35 0.635 77 767 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.13 1.06 – 1.21 0.000105 1209 11967 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.14 0.999 – 1.3 0.0513 262 2611 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.18 1.02 – 1.36 0.0273 219 2182 all phecode
716 Other arthropathies Musculoskeletal 1.12 1.09 – 1.14 4.67e-23 13482 31305 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.12 0.958 – 1.31 0.157 192 1920 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.995 0.825 – 1.2 0.961 131 1293 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.12 1.09 – 1.14 3.41e-23 13410 31294 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.978 0.854 – 1.12 0.744 261 2565 all phecode
720 Spinal stenosis Musculoskeletal 1.1 1.06 – 1.14 3.78e-07 3958 28539 all phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1.1 1.06 – 1.15 2.61e-06 2872 23656 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1.05 1.02 – 1.08 0.00136 5509 32391 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.05 1.01 – 1.08 0.0044 5153 31896 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.09 1.02 – 1.18 0.0184 867 8629 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.17 1.03 – 1.34 0.0196 262 2600 all phecode
722 Intervertebral disc disorders Musculoskeletal 1.08 1.05 – 1.11 7.72e-08 6284 34317 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.06 1.02 – 1.1 0.0025 3591 31411 all phecode
722.3 Schmorl's nodes Musculoskeletal 0.996 0.816 – 1.21 0.966 126 1248 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.07 1.03 – 1.1 0.000318 3957 30744 all phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.09 0.987 – 1.2 0.0917 515 5140 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.07 0.955 – 1.19 0.256 397 3968 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.06 1.01 – 1.11 0.0222 1932 19288 all phecode
723 Other disorders of cervical region Musculoskeletal 0.99 0.923 – 1.06 0.772 952 9495 all phecode
723.1 Torticollis Musculoskeletal 0.993 0.869 – 1.13 0.915 254 2522 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.04 1.01 – 1.08 0.0176 4130 31954 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.04 0.994 – 1.09 0.0906 2307 21902 all phecode
724.2 Disorders of coccyx Musculoskeletal 0.984 0.886 – 1.09 0.76 426 4215 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.08 1 – 1.16 0.0384 931 9295 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.07 1.01 – 1.13 0.0244 1412 14087 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.987 0.964 – 1.01 0.305 9917 30176 all phecode
726.1 Enthesopathy Musculoskeletal 0.983 0.957 – 1.01 0.225 7507 30106 all phecode
726.2 Synoviopathy Musculoskeletal 0.976 0.912 – 1.05 0.492 1015 9987 all phecode
726.3 Bursitis Musculoskeletal 0.981 0.932 – 1.03 0.47 1829 16722 all phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 1 0.944 – 1.07 0.882 1193 11485 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.01 0.981 – 1.04 0.547 7425 30105 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.01 0.972 – 1.05 0.578 3092 24998 all phecode
727.2 Bursitis disorders Musculoskeletal 1.03 0.926 – 1.15 0.577 419 4112 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.984 0.928 – 1.04 0.587 1400 13621 all phecode
727.5 Rupture of synovium Musculoskeletal 1.13 1.02 – 1.25 0.0162 480 4672 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.98 0.937 – 1.02 0.364 2461 21948 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.03 0.942 – 1.12 0.529 591 5893 all phecode
727.8 Plica syndrome Musculoskeletal 0.905 0.754 – 1.09 0.285 130 1264 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.05 1.01 – 1.08 0.00524 4546 29473 all phecode
728.1 Muscular calcification and ossification Musculoskeletal 0.927 0.736 – 1.17 0.52 85 843 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.912 0.806 – 1.03 0.147 297 2949 all phecode
728.7 Fasciitis Musculoskeletal 0.981 0.941 – 1.02 0.373 2814 23463 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.849 0.763 – 0.944 0.00247 419 4138 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.13 1.09 – 1.18 2.49e-11 3642 27471 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.04 0.816 – 1.34 0.729 74 726 all phecode
729.3 Panniculitis Musculoskeletal 1.25 1.02 – 1.53 0.0294 119 1174 all phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 0.98 0.757 – 1.27 0.881 67 664 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.11 0.963 – 1.29 0.146 210 2091 all phecode
732 Osteochondropathies Musculoskeletal 1.06 0.949 – 1.19 0.292 361 3604 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.22 1.04 – 1.43 0.0129 198 1969 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.867 0.69 – 1.09 0.22 90 882 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.924 0.893 – 0.956 5.28e-06 4543 26941 all phecode
733.2 Cyst of bone Musculoskeletal 1 0.858 – 1.17 0.98 190 1900 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.988 0.898 – 1.09 0.805 518 5160 all phecode
733.6 Costochondritis Musculoskeletal 0.973 0.868 – 1.09 0.64 357 3562 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.04 0.962 – 1.12 0.337 822 8205 all phecode
733.9 Chondromalacia Musculoskeletal 1.01 0.817 – 1.24 0.936 96 960 all phecode
735 Acquired foot deformities Musculoskeletal 0.972 0.936 – 1.01 0.138 3417 29622 all phecode
735.1 Flat foot Musculoskeletal 0.996 0.914 – 1.09 0.921 620 6092 all phecode
735.2 Acquired toe deformities Musculoskeletal 0.963 0.906 – 1.02 0.224 1323 11983 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.986 0.913 – 1.07 0.727 825 7494 all phecode
735.23 Hallux rigidus Musculoskeletal 0.925 0.83 – 1.03 0.159 405 4005 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.947 0.894 – 1 0.0586 1470 14295 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.986 0.946 – 1.03 0.5 2763 26555 all phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.929 0.754 – 1.14 0.487 104 1033 all phecode
736.2 Acquired deformities of finger Musculoskeletal 0.896 0.772 – 1.04 0.153 215 2142 all phecode
736.3 Acquired deformities of hip Musculoskeletal 1.13 0.855 – 1.5 0.387 60 590 all phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.98 0.871 – 1.1 0.732 325 3247 all phecode
736.5 Acquired deformities of knee Musculoskeletal 0.939 0.821 – 1.07 0.357 246 2460 all phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.974 0.868 – 1.09 0.66 339 3365 all phecode
737 Curvature of spine Musculoskeletal 0.939 0.889 – 0.992 0.0249 1566 15543 all phecode
737.1 Kyphosis (acquired) Musculoskeletal 0.959 0.867 – 1.06 0.408 479 4748 all phecode
737.2 Lordosis (acquired) Musculoskeletal 1.08 0.843 – 1.39 0.535 70 700 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.927 0.871 – 0.987 0.0179 1203 11982 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1 0.957 – 1.04 0.983 2443 24187 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.13 1.05 – 1.21 0.000497 1057 10542 all phecode
739 Contracture of joint Musculoskeletal 0.967 0.886 – 1.05 0.442 621 6207 all phecode
740 Osteoarthrosis Musculoskeletal 1.12 1.1 – 1.15 4.44e-27 16169 30268 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.09 1.06 – 1.13 6.76e-10 7005 27422 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.09 1.05 – 1.12 7.68e-08 6176 26155 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.1 1.02 – 1.2 0.0194 713 7116 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.07 1.01 – 1.13 0.0292 1609 12092 all phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 1.15 1.03 – 1.29 0.0157 373 3586 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.13 1.11 – 1.16 1.48e-28 15497 30141 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.02 0.997 – 1.05 0.0826 8555 35884 all phecode
741.1 Ankylosis of joint Musculoskeletal 0.962 0.838 – 1.1 0.584 245 2445 all phecode
741.2 Stiffness of joint Musculoskeletal 0.933 0.877 – 0.992 0.0261 1268 12594 all phecode
741.3 Difficulty in walking Musculoskeletal 1.08 1.04 – 1.13 0.000312 2558 23116 all phecode
741.4 Joint effusions Musculoskeletal 1.01 0.967 – 1.06 0.652 2493 24199 all phecode
741.5 Hemarthrosis Musculoskeletal 1.12 0.896 – 1.39 0.325 94 937 all phecode
741.6 Villonodular synovitis Musculoskeletal 0.945 0.73 – 1.22 0.669 68 666 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.989 0.956 – 1.02 0.499 4404 33771 all phecode
742.1 Loose body in joint Musculoskeletal 1.13 0.951 – 1.34 0.167 156 1554 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.865 0.762 – 0.981 0.0244 280 2792 all phecode
742.8 Articular cartilage disorder Musculoskeletal 0.988 0.861 – 1.13 0.868 245 2450 all phecode
742.9 Other derangement of joint Musculoskeletal 0.99 0.957 – 1.02 0.57 4107 32972 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.943 0.92 – 0.967 5.31e-06 9223 36921 all phecode
743.1 Osteoporosis Musculoskeletal 0.919 0.884 – 0.955 1.85e-05 3712 19477 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.919 0.884 – 0.956 2.23e-05 3657 19276 all phecode
743.12 Senile osteoporosis Musculoskeletal 0.842 0.773 – 0.917 7.57e-05 703 5804 all phecode
743.13 Other specified osteoporosis Musculoskeletal 0.889 0.786 – 1.01 0.0605 321 3141 all phecode
743.2 Pathologic fracture Musculoskeletal 0.937 0.878 – 1 0.0547 1112 10563 all phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 0.924 0.835 – 1.02 0.124 475 4629 all phecode
743.22 Pathologic fracture of femur Musculoskeletal 0.964 0.803 – 1.16 0.697 143 1391 all phecode
743.4 Stress fracture Musculoskeletal 0.896 0.805 – 0.998 0.0465 407 4046 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.934 0.908 – 0.961 1.85e-06 6970 35237 all phecode
745 Pain in joint Musculoskeletal 0.992 0.973 – 1.01 0.427 19848 26918 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.01 0.961 – 1.05 0.794 2236 22256 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.03 0.98 – 1.09 0.229 1767 17598 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.942 0.865 – 1.02 0.164 650 6497 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.09 1.01 – 1.18 0.026 751 7480 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.05 0.94 – 1.16 0.409 410 4090 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.937 0.853 – 1.03 0.182 501 5010 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.975 0.798 – 1.19 0.803 111 1110 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.895 0.817 – 0.98 0.0167 555 5549 all phecode
749.1 Cleft palate Congenital Anomalies 0.78 0.628 – 0.969 0.0247 97 970 all phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.908 0.74 – 1.11 0.353 105 1041 all phecode
750 Digestive congenital anomalies Congenital Anomalies 1 0.932 – 1.08 0.956 893 8919 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.978 0.874 – 1.09 0.695 366 3655 all phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 1.01 0.832 – 1.22 0.926 119 1185 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.927 0.747 – 1.15 0.493 99 982 all phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 0.992 0.827 – 1.19 0.933 134 1332 all phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 1.02 0.776 – 1.35 0.864 60 593 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.01 0.919 – 1.11 0.832 531 5300 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.01 0.892 – 1.14 0.895 313 3129 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.01 0.875 – 1.17 0.861 222 2214 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.998 0.951 – 1.05 0.945 2008 19975 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.979 0.894 – 1.07 0.642 574 5740 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.01 0.902 – 1.12 0.907 384 3840 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.953 0.803 – 1.13 0.579 153 1527 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.01 0.953 – 1.07 0.737 1379 13704 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.984 0.919 – 1.05 0.653 976 9685 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.988 0.874 – 1.12 0.854 294 2927 all phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 0.97 0.827 – 1.14 0.703 182 1809 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.13 1.06 – 1.21 0.00014 1133 11313 all phecode
752.1 Neural tube defects Congenital Anomalies 1.15 1.08 – 1.24 7.67e-05 923 9209 all phecode
752.11 Spina bifida Congenital Anomalies 1.1 0.934 – 1.29 0.262 176 1760 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.05 0.909 – 1.2 0.531 232 2320 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.1 0.943 – 1.28 0.228 207 2051 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.01 0.755 – 1.34 0.965 58 580 all phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 1.16 0.857 – 1.56 0.342 56 546 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.09 1.02 – 1.16 0.00749 1216 12116 all phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 1.03 0.858 – 1.25 0.722 135 1333 all phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 1.11 1.01 – 1.22 0.0251 558 5570 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.04 0.958 – 1.12 0.37 747 7458 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 1 0.898 – 1.12 0.939 368 3663 all phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 1.04 0.82 – 1.33 0.722 74 740 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.06 0.943 – 1.2 0.314 321 3205 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.07 0.913 – 1.26 0.395 185 1847 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.986 0.93 – 1.05 0.638 1358 13579 all phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.956 0.738 – 1.24 0.732 68 680 all phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 1.08 0.842 – 1.4 0.529 71 694 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.915 0.815 – 1.03 0.136 335 3346 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.994 0.929 – 1.06 0.87 1003 10014 all phecode
757 Congenital anomalies of the integument Congenital Anomalies 0.889 0.799 – 0.99 0.0321 401 4001 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.918 0.785 – 1.08 0.29 185 1845 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.915 0.762 – 1.1 0.337 135 1349 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.989 0.903 – 1.08 0.803 557 5566 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.945 0.735 – 1.21 0.657 71 710 all phecode
760 Back pain Symptoms 1.06 1.04 – 1.08 2.35e-08 16037 30719 all phecode
761 Cervicalgia Symptoms 1 0.976 – 1.03 0.831 6528 39755 all phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 1.04 1 – 1.08 0.0317 3657 32599 all phecode
764 Sciatica Symptoms 1.08 1.04 – 1.12 5.73e-05 3542 32015 all phecode
765 Cervical radiculitis Symptoms 1.02 0.971 – 1.08 0.397 1799 17851 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.05 1.02 – 1.09 0.000999 5124 37132 all phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.01 0.833 – 1.23 0.915 117 1168 all phecode
769 Nonallopathic lesions NEC Symptoms 0.996 0.933 – 1.06 0.898 1131 11220 all phecode
770 Myalgia and myositis unspecified Symptoms 1.06 1.03 – 1.09 8.98e-05 5533 34303 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.06 1.02 – 1.09 0.000541 4799 35575 all phecode
771.1 Swelling of limb Symptoms 1.13 1.1 – 1.16 9.09e-16 5743 35539 all phecode
771.2 Cramp of limb Symptoms 1.08 1.01 – 1.15 0.0282 1079 10568 all phecode
772 Symptoms of the muscles Symptoms 0.93 0.886 – 0.976 0.00306 2042 20221 all phecode
772.1 Muscular wasting and disuse atrophy Symptoms 0.933 0.84 – 1.04 0.198 422 4199 all phecode
772.2 Spasm of muscle Symptoms 1.02 0.971 – 1.06 0.485 2299 22726 all phecode
772.3 Muscle weakness Symptoms 1.08 1.04 – 1.12 0.000221 2949 28064 all phecode
772.4 Rhabdomyolysis Symptoms 1.07 0.907 – 1.27 0.404 159 1572 all phecode
772.6 Facial weakness Symptoms 0.956 0.865 – 1.06 0.381 478 4742 all phecode
780 Hypothermia/Chills Symptoms 1.05 0.951 – 1.17 0.321 453 4514 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.04 1 – 1.09 0.0378 2822 26225 all phecode
781.1 Loss of height Symptoms 0.958 0.79 – 1.16 0.664 130 1269 all phecode
781.2 Abnormal posture Symptoms 0.98 0.746 – 1.29 0.883 57 567 all phecode
782.3 Edema Symptoms 1.17 1.14 – 1.21 1.58e-26 5874 36788 all phecode
782.6 Pallor and flushing Symptoms 0.938 0.873 – 1.01 0.0816 927 9252 all phecode
783 Fever of unknown origin Symptoms 1.06 1.03 – 1.09 5.52e-05 5733 40720 all phecode
783.1 Postprocedural fever Symptoms 1.13 0.995 – 1.28 0.0599 300 2992 all phecode
785 Abdominal pain Symptoms 1.04 1.01 – 1.06 0.000771 16458 30297 all phecode
788 Syncope and collapse Symptoms 1.02 0.985 – 1.06 0.255 3851 35832 all phecode
789 Nausea and vomiting Symptoms 1.05 1.03 – 1.08 1.02e-05 10568 36098 all phecode
789.1 Persistent vomiting Symptoms 1.18 1.09 – 1.27 1.72e-05 798 7924 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.06 1.02 – 1.11 0.00618 2363 22690 all phecode
790.1 Elevated sedimentation rate Symptoms 1.13 0.98 – 1.3 0.0932 236 2322 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.06 1.03 – 1.09 4.24e-05 7539 37788 all phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.14 1.01 – 1.29 0.0318 309 3075 all phecode
790.9 Abnormal arterial blood gases Symptoms 1.23 1.03 – 1.46 0.024 155 1521 all phecode
791 Gangrene Symptoms 1.11 0.979 – 1.25 0.106 313 3115 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 0.992 0.95 – 1.03 0.695 2820 14872 all phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 1.01 0.948 – 1.08 0.731 1100 9861 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.02 0.924 – 1.12 0.739 515 5133 all phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 0.996 0.95 – 1.04 0.852 2182 20242 all phecode
795.8 Abnormal tumor markers Symptoms 0.933 0.885 – 0.983 0.00914 1745 15551 all phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 1.19 0.908 – 1.57 0.205 61 605 all phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 0.88 0.754 – 1.03 0.104 201 2000 all phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.891 0.847 – 0.937 7.52e-06 2125 9930 all phecode
797 Shock Symptoms 1.06 0.974 – 1.16 0.172 605 6050 all phecode
797.1 Cardiogenic shock Symptoms 1.12 0.977 – 1.29 0.104 242 2420 all phecode
798 Malaise and fatigue Symptoms 1.01 0.99 – 1.04 0.265 11539 35196 all phecode
798.1 Chronic fatigue syndrome Symptoms 1 0.95 – 1.05 0.985 1823 17795 all phecode
800 Fracture of lower limb Injuries & Poisonings 1.01 0.961 – 1.05 0.817 2344 22951 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.995 0.903 – 1.1 0.92 512 4961 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.957 0.879 – 1.04 0.306 670 6582 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.04 0.973 – 1.12 0.23 898 8966 all phecode
800.4 Fracture of patella Injuries & Poisonings 1.01 0.9 – 1.13 0.86 346 3456 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.01 0.97 – 1.06 0.54 2358 22645 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.03 0.963 – 1.1 0.414 1120 11178 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.978 0.875 – 1.09 0.692 380 3765 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.941 0.897 – 0.987 0.0122 2051 20360 all phecode
803.1 Fracture of humerus Injuries & Poisonings 0.991 0.915 – 1.07 0.829 734 7322 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.926 0.868 – 0.989 0.0211 1112 11075 all phecode
803.21 Colles' fracture Injuries & Poisonings 0.913 0.803 – 1.04 0.161 291 2904 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.893 0.812 – 0.982 0.0199 514 5140 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.937 0.888 – 0.989 0.0174 1628 16042 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.999 0.941 – 1.06 0.967 1336 13242 all phecode
807 Fracture of ribs Injuries & Poisonings 0.986 0.908 – 1.07 0.733 683 6815 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.965 0.927 – 1 0.0777 2941 28633 all phecode
816 Cerebral laceration and contusion Injuries & Poisonings 1.31 0.982 – 1.74 0.0668 54 531 all phecode
817 Concussion Injuries & Poisonings 1.01 0.946 – 1.08 0.732 1018 10149 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.915 0.81 – 1.03 0.151 311 3104 all phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 1.01 0.812 – 1.26 0.914 90 895 all phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 0.955 0.767 – 1.19 0.68 97 970 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.968 0.925 – 1.01 0.159 2287 22671 all phecode
830 Dislocation Injuries & Poisonings 0.948 0.916 – 0.982 0.003 3862 34720 all phecode
835 Internal derangement of knee Injuries & Poisonings 0.985 0.941 – 1.03 0.53 2231 21628 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.04 0.946 – 1.15 0.392 496 4954 all phecode
840 Sprains and strains Injuries & Poisonings 0.965 0.941 – 0.991 0.00727 7838 37998 all phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.959 0.873 – 1.05 0.382 537 5356 all phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 1.01 0.96 – 1.07 0.63 1640 16263 all phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.942 0.905 – 0.981 0.00401 2875 24879 all phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.967 0.915 – 1.02 0.227 1583 15592 all phecode
842 Other sprains and strains Injuries & Poisonings 0.967 0.913 – 1.02 0.26 1407 13924 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.08 1.03 – 1.14 0.000833 2072 20649 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.14 1.09 – 1.18 1.66e-10 2982 27545 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.07 0.967 – 1.18 0.193 460 4600 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.14 1.09 – 1.2 6.52e-08 1985 19675 all phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 0.995 0.871 – 1.14 0.938 264 2640 all phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.06 0.936 – 1.21 0.344 293 2929 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.11 1.05 – 1.18 0.000375 1310 13087 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.08 1.03 – 1.13 0.00138 2213 21944 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.08 1.03 – 1.13 0.00226 2110 21070 all phecode
860 Bone marrow or stem cell transplant Neoplasms 0.997 0.842 – 1.18 0.975 166 1660 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.05 1.02 – 1.09 0.00265 4117 36734 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.03 0.884 – 1.19 0.721 204 2026 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.967 0.811 – 1.15 0.705 144 1437 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.936 0.883 – 0.993 0.0293 1346 13301 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.948 0.817 – 1.1 0.48 207 2057 all phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 0.954 0.837 – 1.09 0.474 275 2724 all phecode
870.6 Open wound of neck Injuries & Poisonings 1.04 0.898 – 1.21 0.594 214 2128 all phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.16 0.971 – 1.39 0.101 144 1440 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.04 1 – 1.08 0.0374 3530 32903 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.977 0.891 – 1.07 0.611 572 5701 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.948 0.885 – 1.02 0.138 984 9772 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.32 1.2 – 1.45 2.99e-08 490 4843 all phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.25 1.1 – 1.42 0.000504 295 2921 all phecode
872 Traumatic amputation Injuries & Poisonings 1.12 1.02 – 1.23 0.0151 551 5477 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.24 1.05 – 1.45 0.0107 170 1697 all phecode
875 Non-healing surgical wound Injuries & Poisonings 1.19 1.09 – 1.31 0.00012 572 5720 all phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.27 1.18 – 1.37 6.82e-10 802 8003 all phecode
907 Injuries to the nervous system Injuries & Poisonings 0.996 0.93 – 1.07 0.901 1010 10096 all phecode
910 Superficial injury, infected Injuries & Poisonings 0.902 0.742 – 1.1 0.298 119 1161 all phecode
911 Blister Injuries & Poisonings 1.21 1.07 – 1.37 0.00269 302 2996 all phecode
912 Insect bite Injuries & Poisonings 1.03 0.93 – 1.13 0.61 492 4886 all phecode
913 Toxic effect of venom Injuries & Poisonings 0.791 0.701 – 0.891 0.000123 337 3326 all phecode
916 Contusion Injuries & Poisonings 1.04 1 – 1.07 0.0358 4296 38033 all phecode
930 Allergic reaction to food Injuries & Poisonings 1.01 0.932 – 1.09 0.846 763 7596 all phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.917 0.845 – 0.995 0.0367 714 7072 all phecode
938 Dermatitis due to solar radiation Dermatologic 0.907 0.879 – 0.936 6.86e-10 5567 29098 all phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.993 0.856 – 1.15 0.926 217 2164 all phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.899 0.871 – 0.928 5.02e-11 5307 28656 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.995 0.968 – 1.02 0.738 6704 32389 all phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 0.908 0.723 – 1.14 0.406 91 870 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.04 0.887 – 1.21 0.659 188 1880 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.1 0.963 – 1.26 0.161 269 2688 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.979 0.888 – 1.08 0.678 500 4940 all phecode
947 Urticaria Dermatologic 0.99 0.929 – 1.06 0.763 1177 11454 all phecode
949 Allergies, other Injuries & Poisonings 1.02 0.993 – 1.05 0.151 7251 32350 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.11 1 – 1.22 0.0414 494 4940 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.909 0.755 – 1.09 0.313 136 1352 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.05 0.987 – 1.12 0.125 1217 12158 all phecode
958.1 Postoperative shock Injuries & Poisonings 0.977 0.826 – 1.16 0.783 169 1688 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.07 0.867 – 1.31 0.541 114 1140 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.12 1.07 – 1.17 3.94e-07 2479 22087 all phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 1.18 1.04 – 1.33 0.0076 342 3403 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.11 1.06 – 1.18 9.37e-05 1636 16005 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.12 1.02 – 1.22 0.0206 528 5234 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.09 1.02 – 1.17 0.00827 1065 10347 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.07 0.991 – 1.16 0.0854 803 7976 all phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.08 0.963 – 1.2 0.194 379 3782 all phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 1.23 0.943 – 1.61 0.127 62 612 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.09 0.983 – 1.2 0.103 478 4773 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.03 0.987 – 1.08 0.175 2533 24531 all phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.03 0.991 – 1.08 0.124 2469 24057 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.13 1.04 – 1.22 0.00329 743 7337 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.13 1.04 – 1.23 0.00282 712 7027 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.04 0.966 – 1.12 0.299 864 8601 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.16 1.1 – 1.23 1.85e-07 1469 14402 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.965 0.791 – 1.18 0.727 119 1182 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.962 0.782 – 1.18 0.714 103 1006 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.997 0.938 – 1.06 0.936 1254 12464 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.14 1 – 1.3 0.0476 281 2797 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.16 0.898 – 1.51 0.251 67 643 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.19 1.05 – 1.35 0.00774 288 2858 all phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 1.2 0.953 – 1.52 0.12 80 776 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.2 0.974 – 1.47 0.0869 104 1034 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.01 0.826 – 1.23 0.923 113 1130 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.03 0.819 – 1.31 0.776 81 810 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.16 0.906 – 1.49 0.235 71 703 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.11 1.05 – 1.17 8.19e-05 1763 16599 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.05 1.01 – 1.09 0.0132 3448 30885 all phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 0.991 0.935 – 1.05 0.755 1391 13877 all phecode
985 Toxic effect of other metals Injuries & Poisonings 1.3 0.981 – 1.71 0.0677 57 564 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.05 0.873 – 1.27 0.589 129 1275 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.03 0.992 – 1.06 0.127 3927 31223 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.14 1.08 – 1.19 7.5e-08 2192 21710 all phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.16 1.02 – 1.32 0.0198 291 2910 all phecode
994.2 Sepsis Injuries & Poisonings 1.13 1.08 – 1.18 5.36e-07 2086 20666 all phecode
994.21 Septic shock Injuries & Poisonings 1.14 1.04 – 1.24 0.00334 627 6260 all phecode
008 Intestinal infection Infectious Diseases 1.01 0.932 – 1.09 0.822 745 6950 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.22 1.08 – 1.38 0.0014 321 2987 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.21 1.05 – 1.39 0.00714 251 2331 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 0.947 0.804 – 1.12 0.515 168 1792 exclusion phecode
010 Tuberculosis Infectious Diseases 1 0.769 – 1.31 0.974 61 539 exclusion phecode
031 Diseases due to other mycobacteria Infectious Diseases 1.01 0.69 – 1.49 0.944 27 197 exclusion phecode
038 Septicemia Infectious Diseases 1.22 1.11 – 1.34 2.76e-05 551 5136 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.25 1.02 – 1.53 0.0288 115 1172 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.46 1.08 – 1.98 0.0142 50 455 exclusion phecode
038.3 Bacteremia Infectious Diseases 1.19 1.04 – 1.36 0.00931 266 2396 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.13 1.06 – 1.2 0.000115 1319 9006 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.3 1.16 – 1.46 4.62e-06 349 3617 exclusion phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.4 1.2 – 1.64 2.37e-05 181 1916 exclusion phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.37 1.16 – 1.62 0.000223 157 1700 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.2 1.07 – 1.34 0.00114 381 3462 exclusion phecode
041.21 Rheumatic fever / chorea Infectious Diseases 1.17 0.867 – 1.57 0.311 50 554 exclusion phecode
041.4 E. coli Infectious Diseases 1.21 1.05 – 1.39 0.00703 260 2614 exclusion phecode
041.8 H. pylori Infectious Diseases 0.971 0.738 – 1.28 0.833 58 595 exclusion phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.22 0.977 – 1.52 0.0798 96 849 exclusion phecode
053 Herpes zoster Infectious Diseases 0.954 0.852 – 1.07 0.42 369 3324 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.09 0.805 – 1.47 0.587 50 459 exclusion phecode
054 Herpes simplex Infectious Diseases 1 0.903 – 1.12 0.93 422 3794 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.11 0.946 – 1.3 0.202 193 1614 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 2.3 1.1 – 4.8 0.0269 11 160 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.96 0.705 – 1.31 0.794 52 441 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.27 1.05 – 1.54 0.0136 129 966 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.22 0.904 – 1.66 0.191 53 395 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.13 0.983 – 1.3 0.0857 245 2187 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.76 1.29 – 2.39 0.000312 59 289 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.85 1.33 – 2.59 0.000279 50 218 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.916 0.852 – 0.986 0.0187 911 7141 exclusion phecode
079 Viral infection Infectious Diseases 0.978 0.926 – 1.03 0.425 1707 8160 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.897 0.836 – 0.963 0.0028 975 7161 exclusion phecode
079.2 Infectious mononucleosis Infectious Diseases 0.762 0.617 – 0.941 0.0117 106 885 exclusion phecode
079.9 Viremia, NOS Infectious Diseases 1.21 1.05 – 1.4 0.011 214 2028 exclusion phecode
080 Postoperative infection Infectious Diseases 1.2 1.09 – 1.32 0.000103 540 5845 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.26 1.13 – 1.41 2.47e-05 389 3473 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.08 0.951 – 1.23 0.238 277 2444 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.997 0.915 – 1.09 0.948 644 6718 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 1 0.913 – 1.1 0.978 555 6022 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.996 0.885 – 1.12 0.948 340 3534 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.02 0.846 – 1.24 0.817 129 1645 exclusion phecode
110.13 Dermatophytosis of the body Infectious Diseases 0.951 0.792 – 1.14 0.588 131 1711 exclusion phecode
110.2 Dermatomycoses Infectious Diseases 1.03 0.835 – 1.28 0.761 103 952 exclusion phecode
112 Candidiasis Infectious Diseases 1.11 1.03 – 1.19 0.00526 876 7564 exclusion phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.02 0.784 – 1.33 0.87 57 1616 exclusion phecode
117 Mycoses Infectious Diseases 1.11 0.932 – 1.31 0.249 164 1439 exclusion phecode
117.1 Histoplasmosis Infectious Diseases 0.99 0.646 – 1.52 0.964 23 193 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.5 1.1 – 2.04 0.00975 49 340 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.793 0.582 – 1.08 0.141 48 434 exclusion phecode
130.1 Lyme disease Infectious Diseases 0.816 0.569 – 1.17 0.268 38 309 exclusion phecode
131 Protozoan infection Infectious Diseases 1.3 0.739 – 2.3 0.361 11 163 exclusion phecode
132 Infestation (lice, mites) Infectious Diseases 1.29 0.95 – 1.75 0.103 46 468 exclusion phecode
134 Helminthiases Infectious Diseases 1.1 0.696 – 1.73 0.693 22 177 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.17 0.667 – 2.07 0.578 16 108 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.13 1.05 – 1.22 0.00153 854 7457 exclusion phecode
145 Cancer of mouth Neoplasms 1.3 1.17 – 1.46 2.38e-06 402 2723 exclusion phecode
145.1 Cancer of lip Neoplasms 1.51 0.92 – 2.49 0.103 16 137 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.32 1.12 – 1.56 0.000927 186 1121 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.922 0.723 – 1.18 0.514 79 717 exclusion phecode
145.4 Cancer of the gums Neoplasms 1.7 1.24 – 2.34 0.000961 54 343 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.63 1.24 – 2.14 0.00043 75 363 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.33 1.18 – 1.5 2.58e-06 355 2312 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.66 1.31 – 2.1 3.06e-05 105 568 exclusion phecode
149.2 Cancer of nasopharynx Neoplasms 1.49 0.983 – 2.27 0.0599 33 211 exclusion phecode
149.3 Cancer of hypopharynx Neoplasms 1.31 0.868 – 1.97 0.199 28 154 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.37 1.11 – 1.7 0.00386 102 636 exclusion phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 1.42 1.18 – 1.71 0.000173 148 971 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.16 0.861 – 1.55 0.334 60 466 exclusion phecode
150 Cancer of esophagus Neoplasms 1.65 1.32 – 2.06 1.13e-05 99 751 exclusion phecode
151 Cancer of stomach Neoplasms 1.11 0.903 – 1.37 0.319 112 884 exclusion phecode
153 Colorectal cancer Neoplasms 1.01 0.891 – 1.14 0.915 307 2977 exclusion phecode
153.2 Colon cancer Neoplasms 0.992 0.86 – 1.14 0.913 224 2327 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.996 0.854 – 1.16 0.964 194 1749 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.16 0.943 – 1.44 0.157 109 958 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.09 0.854 – 1.4 0.477 72 634 exclusion phecode
157 Pancreatic cancer Neoplasms 1.07 0.869 – 1.33 0.506 119 943 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.05 0.934 – 1.18 0.417 366 3192 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.06 0.947 – 1.18 0.317 398 3485 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.813 0.583 – 1.13 0.224 44 428 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.11 0.787 – 1.58 0.541 44 300 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.16 0.893 – 1.51 0.263 74 624 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.892 0.619 – 1.29 0.541 36 255 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.11 0.98 – 1.25 0.101 327 2562 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.03 0.896 – 1.18 0.698 254 2026 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 1.11 1 – 1.23 0.0483 438 3720 exclusion phecode
170.1 Bone cancer Neoplasms 1.28 1.1 – 1.49 0.00152 205 1645 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1.06 0.933 – 1.2 0.376 295 2650 exclusion phecode
172 Skin cancer Neoplasms 0.949 0.898 – 1 0.0575 2005 7136 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.887 0.829 – 0.949 0.000488 1183 6208 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.874 0.801 – 0.954 0.00269 622 5040 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.949 0.895 – 1.01 0.0797 1698 6245 exclusion phecode
172.21 Basal cell carcinoma Neoplasms 0.877 0.812 – 0.947 0.000842 900 4642 exclusion phecode
172.22 Squamous cell carcinoma Neoplasms 1.03 0.942 – 1.14 0.481 583 3196 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.812 0.721 – 0.915 0.000652 363 2293 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.897 0.81 – 0.992 0.0351 472 3913 exclusion phecode
174 Breast cancer Neoplasms 0.923 0.856 – 0.996 0.0388 942 4018 exclusion phecode
174.1 Breast cancer [female] Neoplasms 0.926 0.857 – 1 0.0515 905 3840 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.931 0.861 – 1.01 0.0723 886 3818 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.624 0.471 – 0.826 0.000995 65 592 exclusion phecode
175 Acquired absence of breast Neoplasms 0.868 0.764 – 0.986 0.0292 301 2272 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.06 0.956 – 1.18 0.265 442 3333 exclusion phecode
180.1 Cervical cancer Neoplasms 1.12 0.93 – 1.35 0.233 135 1295 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.04 0.928 – 1.17 0.487 356 2584 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.949 0.773 – 1.17 0.618 105 1877 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.02 0.903 – 1.16 0.709 313 2979 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.943 0.786 – 1.13 0.524 151 1504 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.903 0.735 – 1.11 0.331 120 1139 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.1 0.917 – 1.32 0.299 150 1531 exclusion phecode
185 Cancer of prostate Neoplasms 0.854 0.754 – 0.967 0.013 399 1589 exclusion phecode
187 Cancer of other male genital organs Neoplasms 0.856 0.654 – 1.12 0.256 66 631 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.957 0.568 – 1.61 0.868 14 181 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.717 0.515 – 0.997 0.048 42 389 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.18 0.592 – 2.34 0.643 12 97 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.04 0.945 – 1.15 0.392 474 4570 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.09 0.939 – 1.26 0.258 217 2783 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.06 0.904 – 1.25 0.46 179 2436 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.34 0.935 – 1.91 0.111 43 421 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.04 0.917 – 1.18 0.546 307 2791 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.07 0.94 – 1.22 0.307 290 2565 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.14 0.93 – 1.39 0.211 116 1178 exclusion phecode
190 Cancer of eye Neoplasms 0.891 0.625 – 1.27 0.525 44 274 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.03 0.904 – 1.18 0.631 257 2389 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.984 0.842 – 1.15 0.841 189 1564 exclusion phecode
191.11 Cancer of brain Neoplasms 1.02 0.862 – 1.2 0.837 166 1311 exclusion phecode
193 Thyroid cancer Neoplasms 1.07 0.908 – 1.25 0.438 180 2295 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.14 0.931 – 1.39 0.206 115 1361 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.01 0.964 – 1.06 0.685 3803 6337 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1 0.959 – 1.05 0.854 3739 6336 exclusion phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1.31 1.14 – 1.49 7.99e-05 276 1686 exclusion phecode
196 Radiotherapy Neoplasms 0.95 0.862 – 1.05 0.297 560 3437 exclusion phecode
197 Chemotherapy Neoplasms 1.05 0.985 – 1.13 0.133 1227 5333 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.09 1.01 – 1.16 0.0167 1285 5236 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.08 0.994 – 1.16 0.0721 840 4617 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.14 0.98 – 1.32 0.0907 218 1968 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.05 0.902 – 1.22 0.538 220 1681 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.1 0.934 – 1.3 0.252 193 1429 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.14 0.952 – 1.36 0.158 154 1229 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.29 1.1 – 1.52 0.00175 188 1540 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.05 0.818 – 1.36 0.687 81 608 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.01 0.947 – 1.08 0.719 1222 6068 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.55 1.02 – 2.36 0.0394 30 219 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.19 1.04 – 1.36 0.0115 259 2376 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.24 0.896 – 1.72 0.195 43 384 exclusion phecode
201 Hodgkin's disease Neoplasms 1.25 0.926 – 1.68 0.146 47 409 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.09 0.971 – 1.21 0.148 375 3286 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.07 0.949 – 1.21 0.265 318 2810 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.06 0.902 – 1.25 0.464 183 1510 exclusion phecode
202.22 Reticulosarcoma Neoplasms 0.92 0.648 – 1.31 0.642 36 352 exclusion phecode
202.24 Large cell lymphoma Neoplasms 0.926 0.641 – 1.34 0.685 38 319 exclusion phecode
204 Leukemia Neoplasms 1.01 0.845 – 1.2 0.943 153 1343 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1.06 0.798 – 1.41 0.686 58 448 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.15 0.731 – 1.81 0.545 21 173 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.939 0.662 – 1.33 0.722 38 313 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.02 0.77 – 1.35 0.903 62 505 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.83 0.562 – 1.23 0.35 36 268 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.03 0.581 – 1.81 0.932 16 128 exclusion phecode
204.4 Multiple myeloma Neoplasms 0.996 0.727 – 1.36 0.98 42 438 exclusion phecode
208 Benign neoplasm of colon Neoplasms 0.985 0.936 – 1.04 0.57 2119 8346 exclusion phecode
209 Neuroendocrine tumors Neoplasms 0.996 0.72 – 1.38 0.98 41 515 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.04 0.945 – 1.15 0.402 499 4205 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.07 1.01 – 1.14 0.0146 1559 8697 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.1 0.996 – 1.22 0.0608 437 3952 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.05 0.944 – 1.17 0.37 415 3699 exclusion phecode
214 Lipoma Neoplasms 1.02 0.897 – 1.17 0.723 260 3192 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.977 0.825 – 1.16 0.785 160 2008 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.992 0.927 – 1.06 0.819 1012 9144 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.901 0.86 – 0.943 7.4e-06 2817 8094 exclusion phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 1.2 0.874 – 1.65 0.26 45 416 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.848 0.768 – 0.937 0.00118 502 3752 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.837 0.754 – 0.928 0.000735 464 3438 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.919 0.858 – 0.984 0.016 1154 4797 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.821 0.74 – 0.91 0.000166 461 4411 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.934 0.867 – 1.01 0.0736 944 4715 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.881 0.763 – 1.02 0.0867 226 2392 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.965 0.875 – 1.06 0.47 506 4088 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.777 0.662 – 0.913 0.0021 182 1720 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.07 0.945 – 1.21 0.288 326 2723 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.861 0.726 – 1.02 0.0857 161 1399 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.886 0.736 – 1.07 0.197 134 1127 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.06 0.927 – 1.2 0.414 275 2764 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1 0.868 – 1.16 0.951 213 2174 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.19 0.928 – 1.53 0.168 71 639 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.985 0.863 – 1.12 0.82 259 3226 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.08 0.955 – 1.23 0.211 283 3878 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.19 0.916 – 1.55 0.192 63 965 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.06 0.893 – 1.25 0.517 157 1863 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.02 0.792 – 1.32 0.858 63 1012 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.787 0.715 – 0.867 1.03e-06 538 4535 exclusion phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.743 0.659 – 0.837 1.11e-06 355 2832 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.949 0.897 – 1 0.0625 1669 8554 exclusion phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.946 0.888 – 1.01 0.0894 1210 7778 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.04 0.902 – 1.2 0.581 219 2530 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.02 0.93 – 1.11 0.725 605 5567 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.986 0.892 – 1.09 0.782 475 4945 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.999 0.869 – 1.15 0.987 236 3181 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.05 0.93 – 1.19 0.418 299 3335 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.993 0.818 – 1.21 0.944 118 1249 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.18 0.725 – 1.9 0.512 19 307 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.911 0.707 – 1.17 0.474 72 698 exclusion phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.952 0.674 – 1.34 0.781 38 356 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.05 0.989 – 1.11 0.116 1647 7677 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.977 0.871 – 1.1 0.689 351 4262 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.08 0.954 – 1.23 0.219 284 3037 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.05 0.991 – 1.12 0.0975 1538 7562 exclusion phecode
245 Thyroiditis Endocrine/metabolic 1.18 1.01 – 1.39 0.0406 178 2110 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.28 1.06 – 1.53 0.00849 138 1770 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.28 1.07 – 1.54 0.00812 137 1751 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.04 0.973 – 1.11 0.26 1301 7120 exclusion phecode
246.2 Thyroid cyst Endocrine/metabolic 0.754 0.489 – 1.16 0.201 25 228 exclusion phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1.03 0.892 – 1.19 0.674 218 2156 exclusion phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.05 0.871 – 1.28 0.589 169 1894 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.1 1.04 – 1.17 0.00119 1798 8752 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.2 1.04 – 1.4 0.0158 469 2920 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.85 1.27 – 2.69 0.00134 103 226 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.27 0.999 – 1.62 0.0511 154 616 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.39 1.07 – 1.79 0.0125 189 705 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.6 1.25 – 2.06 0.000211 160 588 exclusion phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 1.26 0.87 – 1.81 0.224 49 173 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.13 1.05 – 1.22 0.00159 1078 7827 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.74 1.16 – 2.62 0.00728 77 288 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.44 1.19 – 1.73 0.000124 173 3130 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.23 1.01 – 1.49 0.0385 207 2284 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.26 1.05 – 1.5 0.0124 215 3893 exclusion phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.31 1.01 – 1.71 0.0452 71 1331 exclusion phecode
250.3 Insulin pump user Endocrine/metabolic 1.29 1.12 – 1.48 0.000348 438 5081 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.08 1 – 1.15 0.0446 1238 8248 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.992 0.852 – 1.15 0.917 232 4125 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.09 1.01 – 1.17 0.0266 1125 7996 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 2.03 1.23 – 3.35 0.00555 26 290 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.29 1.06 – 1.56 0.0101 205 3102 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.16 1 – 1.35 0.0478 256 2093 exclusion phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.07 0.929 – 1.23 0.352 245 1974 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.12 0.964 – 1.29 0.141 310 2348 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.09 0.985 – 1.2 0.0976 477 5165 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.08 0.978 – 1.2 0.123 435 4715 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.17 0.938 – 1.45 0.168 98 1179 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.1 0.936 – 1.3 0.243 164 1895 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.17 0.863 – 1.58 0.313 48 670 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.93 0.549 – 1.57 0.786 11 203 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.97 0.685 – 1.37 0.864 32 477 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.36 0.832 – 2.21 0.222 15 182 exclusion phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 0.925 0.56 – 1.53 0.762 18 220 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.23 0.834 – 1.83 0.294 30 242 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.12 0.983 – 1.27 0.0893 276 3379 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.944 0.717 – 1.24 0.678 56 924 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.73 0.486 – 1.1 0.129 26 495 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.15 0.696 – 1.9 0.583 15 281 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.18 0.98 – 1.43 0.0804 131 1432 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.19 0.981 – 1.44 0.0768 123 1361 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.879 0.766 – 1.01 0.0655 237 3240 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.839 0.666 – 1.06 0.138 78 2257 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1.04 0.865 – 1.26 0.659 127 1530 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.05 0.869 – 1.27 0.603 122 1469 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.79 1.04 – 3.06 0.0346 17 186 exclusion phecode
258.1 Postablative ovarian failure Endocrine/metabolic 1.01 0.703 – 1.47 0.939 31 330 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 1.02 0.874 – 1.19 0.807 201 2439 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.26 1.18 – 1.36 1.26e-10 988 5553 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.32 1.08 – 1.62 0.00642 147 559 exclusion phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.41 1.29 – 1.55 2.14e-13 600 3325 exclusion phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.46 1.25 – 1.72 2.94e-06 214 1201 exclusion phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.42 1.21 – 1.66 1.61e-05 210 1199 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.25 1.09 – 1.43 0.00147 264 1878 exclusion phecode
260.7 Polyphagia Endocrine/metabolic 0.631 0.354 – 1.12 0.118 16 167 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.12 1.05 – 1.18 0.000164 1599 8182 exclusion phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1.69 1.05 – 2.72 0.0295 22 160 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.37 1.16 – 1.62 0.00026 175 1833 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.11 1.05 – 1.18 0.000335 1500 8199 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.06 0.635 – 1.77 0.823 14 118 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.14 0.998 – 1.3 0.0542 269 2874 exclusion phecode
263 Other nutritional deficiency Endocrine/metabolic 1.25 1.11 – 1.4 0.000122 368 3637 exclusion phecode
264 Lack of normal physiological development Endocrine/metabolic 1.01 0.808 – 1.26 0.95 103 699 exclusion phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.05 0.764 – 1.44 0.771 51 309 exclusion phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 0.904 0.644 – 1.27 0.558 38 286 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.33 1.17 – 1.51 1.11e-05 286 3036 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.13 0.969 – 1.31 0.119 201 2098 exclusion phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.896 0.632 – 1.27 0.538 34 418 exclusion phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.866 0.597 – 1.25 0.447 29 348 exclusion phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 1.1 0.614 – 1.98 0.744 10 223 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.19 1 – 1.4 0.0454 164 1518 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.07 0.834 – 1.38 0.583 72 737 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 0.724 0.448 – 1.17 0.188 19 142 exclusion phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 0.834 0.464 – 1.5 0.545 18 134 exclusion phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.38 1.07 – 1.77 0.0129 76 663 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.02 0.917 – 1.13 0.728 417 6296 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1 0.901 – 1.12 0.942 394 6130 exclusion phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.28 0.822 – 1.99 0.275 26 230 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.03 0.98 – 1.08 0.239 2862 7532 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.03 0.981 – 1.08 0.22 2851 7518 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.02 0.947 – 1.11 0.561 885 5677 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.03 0.846 – 1.26 0.763 112 2933 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.01 0.902 – 1.12 0.907 426 4669 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.979 0.738 – 1.3 0.882 61 737 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.21 1.06 – 1.38 0.00418 266 4357 exclusion phecode
274.1 Gout Endocrine/metabolic 1.24 1.08 – 1.43 0.0022 232 4169 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.17 0.957 – 1.43 0.127 106 2021 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.835 0.595 – 1.17 0.298 44 379 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.874 0.619 – 1.24 0.447 43 358 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.19 1.11 – 1.28 1.63e-06 945 8233 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.959 0.642 – 1.43 0.839 27 469 exclusion phecode
275.11 Hereditary hemochromatosis Hematopoietic 1.17 0.567 – 2.42 0.669 7 203 exclusion phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 1.08 0.606 – 1.93 0.789 15 153 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.33 1.17 – 1.52 1.51e-05 273 2426 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.18 1.09 – 1.27 5.27e-05 738 7005 exclusion phecode
275.51 Hypocalcemia Endocrine/metabolic 1.29 1.11 – 1.49 0.0011 218 1971 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.29 1.14 – 1.46 3.81e-05 320 2783 exclusion phecode
275.6 Hypercalcemia Endocrine/metabolic 1.19 1.04 – 1.35 0.00881 290 3120 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.22 1.15 – 1.28 1.47e-13 2041 8801 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.29 1.21 – 1.37 6.58e-16 1364 7723 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.22 0.996 – 1.49 0.0545 127 1035 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.31 1.19 – 1.43 3.89e-09 637 4587 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.34 1.22 – 1.46 1.59e-10 600 5079 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.34 1.21 – 1.48 2.87e-08 444 4590 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.18 1.06 – 1.3 0.00181 443 4136 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.2 1.07 – 1.34 0.00146 371 3556 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.19 0.974 – 1.45 0.0896 124 982 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.25 1.17 – 1.33 4.17e-11 1141 7954 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.45 1.26 – 1.67 2.1e-07 239 2587 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.01 0.658 – 1.55 0.966 24 289 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.15 1.06 – 1.25 0.000663 701 8379 exclusion phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.72 1.18 – 2.51 0.00482 28 771 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1 0.844 – 1.18 0.999 161 1518 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.964 0.807 – 1.15 0.688 143 2051 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.03 0.844 – 1.26 0.756 109 1709 exclusion phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 2 1.29 – 3.11 0.00197 17 1926 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.24 1.14 – 1.34 3.99e-07 678 10325 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.48 1.27 – 1.72 5.23e-07 177 10321 exclusion phecode
278.11 Morbid obesity Endocrine/metabolic 1.58 1.17 – 2.13 0.00302 40 10260 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 1.19 0.841 – 1.67 0.332 31 1298 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.15 1.02 – 1.29 0.0256 307 7284 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.11 1.03 – 1.2 0.00638 806 6578 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.14 1.01 – 1.29 0.0315 328 2565 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.12 0.896 – 1.4 0.316 93 720 exclusion phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 1.03 0.882 – 1.2 0.719 198 1809 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.04 0.97 – 1.11 0.291 1119 8305 exclusion phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 1.13 0.951 – 1.34 0.166 171 1473 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.15 1.07 – 1.23 7.99e-05 1078 7054 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.15 1.07 – 1.23 6.99e-05 1043 7020 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.21 1.08 – 1.34 0.000554 408 3775 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.31 1.07 – 1.62 0.0107 116 1161 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.3 0.979 – 1.74 0.0693 62 579 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.48 0.954 – 2.29 0.08 28 267 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.21 0.847 – 1.73 0.295 43 434 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.28 0.98 – 1.68 0.0696 63 652 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.24 0.959 – 1.61 0.1 69 693 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.23 0.886 – 1.7 0.217 46 437 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.52 1.08 – 2.13 0.015 38 411 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.44 1.01 – 2.07 0.0464 33 345 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.27 0.758 – 2.12 0.366 15 152 exclusion phecode
284 Aplastic anemia Hematopoietic 1.23 1.05 – 1.45 0.0112 181 1365 exclusion phecode
284.1 Pancytopenia Hematopoietic 1.22 1.02 – 1.45 0.0292 157 1208 exclusion phecode
285 Other anemias Hematopoietic 1.16 1.11 – 1.21 2.7e-10 2829 7835 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.19 1.1 – 1.28 1.86e-05 806 5912 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.39 1.27 – 1.54 1.29e-11 523 4091 exclusion phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.47 1.28 – 1.7 1.48e-07 221 1743 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.28 1.09 – 1.51 0.0031 182 1437 exclusion phecode
286 Coagulation defects Hematopoietic 1.09 1.01 – 1.18 0.0226 767 7586 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.828 0.606 – 1.13 0.236 50 594 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.635 0.378 – 1.07 0.0856 20 197 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.991 0.633 – 1.55 0.968 22 307 exclusion phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.09 0.993 – 1.19 0.0711 550 5391 exclusion phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 1.2 0.825 – 1.76 0.336 34 325 exclusion phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 0.991 0.734 – 1.34 0.951 50 500 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.957 0.643 – 1.42 0.828 24 279 exclusion phecode
286.6 Defibrination syndrome Hematopoietic 1.05 0.952 – 1.16 0.335 491 5592 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.05 0.96 – 1.15 0.288 588 6545 exclusion phecode
286.8 Hypercoagulable state Hematopoietic 1.05 0.888 – 1.25 0.558 158 1963 exclusion phecode
286.81 Primary hypercoagulable state Hematopoietic 1.03 0.866 – 1.23 0.727 150 1863 exclusion phecode
286.9 Abnormal coagulation profile Hematopoietic 1.28 1.11 – 1.48 0.000643 224 2405 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.09 1.01 – 1.18 0.0357 740 6201 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.804 0.6 – 1.08 0.143 55 491 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.1 1.01 – 1.2 0.0229 671 5659 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.1 0.909 – 1.34 0.321 119 1303 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.18 0.977 – 1.43 0.0855 135 1209 exclusion phecode
287.4 Qualitative platelet defects Hematopoietic 1.28 0.845 – 1.95 0.244 23 267 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.15 1.08 – 1.23 1.91e-05 1201 8361 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.1 1 – 1.22 0.0433 515 3506 exclusion phecode
288.11 Neutropenia Hematopoietic 1.17 1.04 – 1.31 0.0112 341 2383 exclusion phecode
288.2 Elevated white blood cell count Hematopoietic 1.16 1.08 – 1.24 4.87e-05 962 7794 exclusion phecode
288.3 Eosinophilia Hematopoietic 1.1 0.802 – 1.51 0.557 46 411 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.12 1.01 – 1.24 0.0373 440 3991 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.04 0.902 – 1.2 0.584 232 2168 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.05 0.975 – 1.12 0.214 946 7908 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1.21 0.958 – 1.54 0.109 79 834 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.52 1.07 – 2.17 0.0193 40 463 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.44 1.15 – 1.79 0.00129 99 843 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.08 0.96 – 1.22 0.192 326 2192 exclusion phecode
290.1 Dementias Mental Disorders 0.867 0.711 – 1.06 0.16 116 945 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.893 0.612 – 1.3 0.556 32 269 exclusion phecode
290.12 Dementia with cerebral degenerations Mental Disorders 0.583 0.342 – 0.994 0.0475 15 151 exclusion phecode
290.13 Senile dementia Mental Disorders 0.834 0.652 – 1.07 0.151 75 604 exclusion phecode
290.16 Vascular dementia Mental Disorders 0.944 0.601 – 1.48 0.804 20 144 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.16 0.99 – 1.35 0.0672 200 1357 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.01 0.874 – 1.17 0.864 208 1877 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.1 1 – 1.21 0.0426 540 5706 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.861 0.616 – 1.2 0.38 36 500 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.06 0.885 – 1.27 0.526 135 1160 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.14 1.02 – 1.26 0.0185 404 4403 exclusion phecode
292 Neurological disorders Mental Disorders 1.09 1.03 – 1.16 0.00487 1340 8914 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.11 1.01 – 1.23 0.0293 514 4104 exclusion phecode
292.11 Aphasia Mental Disorders 0.963 0.811 – 1.14 0.665 158 1414 exclusion phecode
292.12 Symbolic dysfunction Mental Disorders 0.801 0.58 – 1.11 0.18 45 448 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.987 0.789 – 1.23 0.907 83 779 exclusion phecode
292.3 Memory loss Mental Disorders 0.903 0.81 – 1.01 0.0643 394 3874 exclusion phecode
292.4 Altered mental status Mental Disorders 1.21 1.1 – 1.33 5.18e-05 544 4644 exclusion phecode
292.5 Transient alteration of awareness Mental Disorders 1.02 0.825 – 1.25 0.879 105 944 exclusion phecode
292.6 Hallucinations Mental Disorders 1.19 0.88 – 1.62 0.257 50 472 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.06 0.86 – 1.31 0.576 109 942 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.06 0.995 – 1.14 0.0691 1033 8730 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.12 0.963 – 1.3 0.142 211 1890 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.03 0.715 – 1.49 0.868 30 327 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.36 0.875 – 2.12 0.171 24 252 exclusion phecode
295.3 Psychosis Mental Disorders 1.18 1 – 1.39 0.0461 175 1527 exclusion phecode
296 Mood disorders Mental Disorders 1.09 1.04 – 1.14 0.000326 3358 5135 exclusion phecode
296.1 Bipolar Mental Disorders 1.21 1.06 – 1.38 0.00379 288 3055 exclusion phecode
296.2 Depression Mental Disorders 1.09 1.04 – 1.14 0.000444 3217 5134 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.09 1.04 – 1.15 0.000278 2978 5134 exclusion phecode
297 Suicidal ideation or attempt Mental Disorders 1.3 1.14 – 1.49 8.99e-05 273 2462 exclusion phecode
297.1 Suicidal ideation Mental Disorders 1.25 1.07 – 1.45 0.00423 211 2001 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.46 1.18 – 1.81 0.000548 99 768 exclusion phecode
300 Anxiety disorders Mental Disorders 1.11 1.06 – 1.16 1.07e-05 3742 5135 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.11 1.06 – 1.17 3.39e-06 3556 5135 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 1.1 1.03 – 1.17 0.00443 1339 4978 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.04 0.918 – 1.18 0.538 330 3115 exclusion phecode
300.13 Phobia Mental Disorders 1.11 0.96 – 1.28 0.159 243 2450 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.792 0.614 – 1.02 0.0711 75 881 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.08 0.985 – 1.19 0.0994 590 4164 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.04 0.834 – 1.3 0.729 103 1260 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.1 0.943 – 1.29 0.222 192 2136 exclusion phecode
301 Personality disorders Mental Disorders 1.24 1.01 – 1.52 0.0387 110 1340 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.4 1.07 – 1.83 0.0146 64 700 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 0.903 0.82 – 0.994 0.038 544 2894 exclusion phecode
302.1 Decreased libido Mental Disorders 0.829 0.666 – 1.03 0.093 97 1003 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.92 0.865 – 0.978 0.00774 1620 4752 exclusion phecode
303.1 Dissociative disorder Mental Disorders 0.972 0.669 – 1.41 0.882 32 423 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.918 0.862 – 0.977 0.00734 1550 4697 exclusion phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.823 0.676 – 1 0.0528 120 1144 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.97 0.856 – 1.1 0.64 312 3000 exclusion phecode
304 Adjustment reaction Mental Disorders 1.07 0.997 – 1.16 0.0583 930 4959 exclusion phecode
305.2 Eating disorder Mental Disorders 1.2 1.01 – 1.43 0.04 145 2340 exclusion phecode
306 Other mental disorder Mental Disorders 1.01 0.911 – 1.12 0.864 464 3668 exclusion phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.04 0.874 – 1.25 0.633 156 1234 exclusion phecode
306.9 Tension headache Mental Disorders 0.92 0.787 – 1.08 0.299 189 2011 exclusion phecode
312 Conduct disorders Mental Disorders 1.26 0.975 – 1.63 0.0772 74 661 exclusion phecode
312.3 Impulse control disorder Mental Disorders 0.984 0.624 – 1.55 0.943 23 218 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 1.13 1.02 – 1.25 0.0179 467 4203 exclusion phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1.14 1.02 – 1.26 0.017 423 3835 exclusion phecode
313.2 Tics and stuttering Mental Disorders 1.08 0.692 – 1.68 0.737 23 217 exclusion phecode
313.3 Autism Mental Disorders 0.93 0.535 – 1.62 0.796 12 202 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.04 0.884 – 1.23 0.616 167 1581 exclusion phecode
315.1 Learning disorder Mental Disorders 0.998 0.668 – 1.49 0.994 25 273 exclusion phecode
315.2 Speech and language disorder Mental Disorders 1.02 0.775 – 1.34 0.897 62 604 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.3 1.21 – 1.4 3.22e-13 963 7539 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.02 0.858 – 1.22 0.81 153 1360 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.21 1.11 – 1.32 8.44e-06 671 4789 exclusion phecode
317.1 Alcoholism Mental Disorders 1.23 1.12 – 1.35 1.02e-05 561 3801 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.19 0.934 – 1.52 0.158 81 651 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.29 1.22 – 1.36 1.34e-21 2004 8160 exclusion phecode
320 Meningitis Neurological 1.03 0.83 – 1.28 0.787 101 872 exclusion phecode
323 Encephalitis Neurological 1.1 0.802 – 1.52 0.544 45 392 exclusion phecode
323.8 Encephalitis, non-infectious Neurological 1.03 0.714 – 1.48 0.887 39 330 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.01 0.76 – 1.34 0.948 52 626 exclusion phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 1.01 0.5 – 2.05 0.975 10 118 exclusion phecode
327 Sleep disorders Neurological 1.02 0.968 – 1.07 0.484 2171 8803 exclusion phecode
327.1 Hypersomnia Neurological 1 0.883 – 1.14 0.941 266 5126 exclusion phecode
327.3 Sleep apnea Neurological 0.963 0.895 – 1.04 0.311 898 8640 exclusion phecode
327.31 Central/nonobstroctive sleep apnea Neurological 0.991 0.786 – 1.25 0.939 81 1103 exclusion phecode
327.32 Obstructive sleep apnea Neurological 0.954 0.876 – 1.04 0.275 639 8241 exclusion phecode
327.4 Insomnia Neurological 1.04 0.973 – 1.1 0.275 1270 8485 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.03 0.91 – 1.17 0.608 286 3274 exclusion phecode
327.5 Parasomnia Neurological 1.01 0.797 – 1.27 0.953 74 1455 exclusion phecode
327.6 Circadian rhythm sleep disorder Neurological 0.882 0.656 – 1.18 0.404 54 740 exclusion phecode
327.7 Sleep related movement disorders Neurological 1.04 0.918 – 1.17 0.55 304 4527 exclusion phecode
327.71 Restless legs syndrome Neurological 1.03 0.902 – 1.18 0.664 263 4037 exclusion phecode
327.72 Sleep related leg cramps Neurological 1.31 0.817 – 2.11 0.261 18 181 exclusion phecode
331 Other cerebral degenerations Neurological 1.26 1.07 – 1.49 0.0058 175 1452 exclusion phecode
331.1 Hydrocephalus Neurological 1.12 0.868 – 1.44 0.384 69 663 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.39 1.12 – 1.72 0.00309 105 817 exclusion phecode
332 Parkinson's disease Neurological 0.986 0.795 – 1.22 0.898 99 706 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.02 0.93 – 1.11 0.731 607 5909 exclusion phecode
333.1 Essential tremor Neurological 1.02 0.864 – 1.21 0.794 163 1443 exclusion phecode
333.2 Myoclonus Neurological 1.21 0.871 – 1.69 0.253 39 365 exclusion phecode
333.4 Torsion dystonia Neurological 0.91 0.738 – 1.12 0.38 113 785 exclusion phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 0.9 0.591 – 1.37 0.621 29 168 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.22 1.05 – 1.42 0.00792 223 2251 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.94 1.14 – 3.3 0.0151 21 164 exclusion phecode
334.2 Anterior horn cell disease Neurological 1.54 1 – 2.37 0.0502 25 213 exclusion phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 1.4 0.805 – 2.43 0.234 17 119 exclusion phecode
335 Multiple sclerosis Neurological 1.07 0.87 – 1.32 0.507 101 931 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.1 0.943 – 1.28 0.23 203 1628 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.49 1.16 – 1.91 0.00191 73 560 exclusion phecode
338 Pain Neurological 1.1 1.05 – 1.14 7.35e-06 4506 6507 exclusion phecode
338.1 Acute pain Neurological 1.11 1.06 – 1.16 2.14e-06 3556 6458 exclusion phecode
338.2 Chronic pain Neurological 1.14 1.08 – 1.2 1.39e-06 2162 6474 exclusion phecode
339 Other headache syndromes Neurological 1.03 0.983 – 1.09 0.197 2155 8099 exclusion phecode
340 Migraine Neurological 1.04 0.987 – 1.11 0.132 1690 7395 exclusion phecode
340.1 Migrain with aura Neurological 1.1 1.02 – 1.18 0.0122 915 6012 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.01 0.704 – 1.44 0.973 34 302 exclusion phecode
342 Hemiplegia Neurological 1.11 0.911 – 1.36 0.296 110 966 exclusion phecode
343 Infantile cerebral palsy Neurological 1.39 0.931 – 2.08 0.107 25 246 exclusion phecode
344 Other paralytic syndromes Neurological 1.28 1.08 – 1.51 0.00463 171 1436 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.08 0.988 – 1.17 0.0913 654 5981 exclusion phecode
345.1 Epilepsy Neurological 1.08 0.926 – 1.27 0.317 194 1787 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 0.924 0.694 – 1.23 0.592 57 582 exclusion phecode
345.12 Partial epilepsy Neurological 1.03 0.856 – 1.25 0.738 138 1235 exclusion phecode
345.3 Convulsions Neurological 1.09 1 – 1.19 0.0416 620 5634 exclusion phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.945 0.684 – 1.31 0.732 40 423 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.1 0.979 – 1.24 0.107 338 3127 exclusion phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.884 0.595 – 1.31 0.542 28 262 exclusion phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 1.09 0.663 – 1.78 0.745 19 257 exclusion phecode
347 Cataplexy and narcolepsy Neurological 1.21 0.765 – 1.9 0.419 20 250 exclusion phecode
348 Other conditions of brain Neurological 1.09 0.979 – 1.21 0.121 425 4047 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.09 0.941 – 1.26 0.258 215 2071 exclusion phecode
348.4 Cerebral cysts Neurological 0.767 0.57 – 1.03 0.0798 53 566 exclusion phecode
348.7 Coma Neurological 1.21 0.909 – 1.62 0.189 57 529 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.27 1.09 – 1.48 0.00264 195 1750 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.01 0.924 – 1.11 0.761 532 5180 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.13 0.985 – 1.3 0.0812 234 2163 exclusion phecode
350 Abnormal movement Neurological 1.07 1.01 – 1.14 0.02 1494 9072 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.1 1.02 – 1.19 0.0154 750 6804 exclusion phecode
350.2 Abnormality of gait Neurological 1.09 1.01 – 1.17 0.036 815 6558 exclusion phecode
350.3 Lack of coordination Neurological 1.03 0.908 – 1.17 0.644 293 2332 exclusion phecode
350.5 Abnormal reflex Neurological 1.17 0.853 – 1.6 0.331 43 453 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.907 0.74 – 1.11 0.347 118 1103 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.06 0.994 – 1.12 0.0777 1352 8345 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.1 0.988 – 1.23 0.0825 379 4003 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.21 1.01 – 1.47 0.0441 125 1317 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.04 0.883 – 1.23 0.633 161 1792 exclusion phecode
353 Nerve root and plexus disorders Neurological 1.07 0.997 – 1.16 0.0603 843 7874 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.975 0.791 – 1.2 0.813 110 956 exclusion phecode
353.2 Nerve root lesions Neurological 1.25 0.807 – 1.93 0.318 24 257 exclusion phecode
355 Complex regional/central pain syndrome Neurological 1.25 1.04 – 1.51 0.0181 131 1290 exclusion phecode
355.1 Chronic pain syndrome Neurological 1.28 1.09 – 1.49 0.00234 181 1965 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.13 1.01 – 1.25 0.0306 395 4283 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.11 1.01 – 1.21 0.0221 623 6312 exclusion phecode
358 Myoneural disorders Neurological 1.14 0.993 – 1.3 0.0627 248 2514 exclusion phecode
358.1 Myasthenia gravis Neurological 0.782 0.516 – 1.18 0.246 26 245 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.926 0.817 – 1.05 0.223 309 2559 exclusion phecode
359.1 Muscular dystrophies Neurological 1.18 0.698 – 1.99 0.54 22 153 exclusion phecode
359.2 Myopathy Neurological 0.917 0.808 – 1.04 0.176 294 2454 exclusion phecode
360 Disorders of the globe Sense Organs 0.955 0.644 – 1.42 0.821 30 266 exclusion phecode
360.2 Progressive myopia Sense Organs 0.75 0.44 – 1.28 0.289 19 128 exclusion phecode
361 Retinal detachments and defects Sense Organs 1.08 0.916 – 1.28 0.349 156 1427 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.969 0.739 – 1.27 0.817 65 551 exclusion phecode
362 Other retinal disorders Sense Organs 0.992 0.913 – 1.08 0.851 747 4729 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.92 0.826 – 1.02 0.13 450 3086 exclusion phecode
362.21 Macular degeneration, dry Sense Organs 0.816 0.639 – 1.04 0.103 89 722 exclusion phecode
362.22 Macular degeneration, wet Sense Organs 0.71 0.463 – 1.09 0.115 34 253 exclusion phecode
362.23 Cystoid macular degeneration of retina Sense Organs 1.01 0.81 – 1.27 0.914 88 800 exclusion phecode
362.26 Macular puckering of retina Sense Organs 0.866 0.734 – 1.02 0.0907 173 1667 exclusion phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.948 0.769 – 1.17 0.62 114 930 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.92 0.822 – 1.03 0.149 403 2769 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.14 0.972 – 1.34 0.106 174 1727 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1.37 1.11 – 1.69 0.00334 87 771 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.986 0.817 – 1.19 0.883 134 1199 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.989 0.794 – 1.23 0.92 97 793 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.02 0.756 – 1.38 0.9 50 491 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.1 0.832 – 1.45 0.51 62 476 exclusion phecode
362.9 Retinal edema Sense Organs 0.996 0.759 – 1.31 0.977 59 565 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.89 0.724 – 1.09 0.267 114 962 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.848 0.658 – 1.09 0.201 73 644 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.978 0.859 – 1.11 0.743 283 2369 exclusion phecode
364.1 Corneal opacity Sense Organs 0.927 0.749 – 1.15 0.484 104 821 exclusion phecode
364.2 Corneal edema Sense Organs 1.29 0.834 – 1.99 0.255 22 244 exclusion phecode
364.4 Corneal degenerations Sense Organs 0.965 0.794 – 1.17 0.725 118 907 exclusion phecode
364.41 Keratoconus Sense Organs 0.531 0.319 – 0.884 0.015 21 155 exclusion phecode
364.5 Corneal dystrophy Sense Organs 1.06 0.86 – 1.32 0.568 106 998 exclusion phecode
364.51 Fuchs' dystrophy Sense Organs 1.27 0.947 – 1.7 0.112 60 530 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.982 0.589 – 1.64 0.946 17 188 exclusion phecode
365 Glaucoma Sense Organs 0.944 0.86 – 1.04 0.226 573 4343 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 1.05 0.88 – 1.24 0.607 166 1308 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.878 0.694 – 1.11 0.277 93 729 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.857 0.644 – 1.14 0.292 67 484 exclusion phecode
366 Cataract Sense Organs 0.986 0.928 – 1.05 0.655 1738 5909 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.916 0.688 – 1.22 0.548 56 430 exclusion phecode
366.2 Senile cataract Sense Organs 0.944 0.878 – 1.02 0.125 1076 5140 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.953 0.905 – 1 0.067 2073 8929 exclusion phecode
367.1 Myopia Sense Organs 0.912 0.855 – 0.972 0.0047 1236 8271 exclusion phecode
367.2 Astigmatism Sense Organs 0.92 0.857 – 0.989 0.0234 963 7507 exclusion phecode
367.8 Hypermetropia Sense Organs 0.922 0.83 – 1.02 0.128 439 4193 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.11 0.972 – 1.26 0.127 276 2785 exclusion phecode
368 Visual disturbances Sense Organs 1.02 0.955 – 1.08 0.634 1304 9189 exclusion phecode
368.1 Amblyopia Sense Organs 1.14 0.954 – 1.36 0.15 142 1495 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.03 0.903 – 1.18 0.628 257 2306 exclusion phecode
368.3 Anisometropia Sense Organs 0.899 0.679 – 1.19 0.456 57 494 exclusion phecode
368.4 Visual field defects Sense Organs 0.91 0.784 – 1.06 0.218 202 2398 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.923 0.804 – 1.06 0.255 246 2456 exclusion phecode
368.91 Psychophysical visual disturbances Sense Organs 1.04 0.683 – 1.57 0.866 30 248 exclusion phecode
369 Infection of the eye Sense Organs 0.886 0.819 – 0.959 0.00279 768 6955 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.855 0.699 – 1.05 0.128 126 1209 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.891 0.818 – 0.971 0.00819 653 6187 exclusion phecode
370 Keratitis Sense Organs 0.86 0.765 – 0.966 0.0112 363 3031 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.874 0.673 – 1.14 0.313 73 497 exclusion phecode
370.2 Superficial keratitis Sense Organs 0.815 0.674 – 0.986 0.0356 135 1226 exclusion phecode
370.3 Keratoconjunctivitis Sense Organs 0.942 0.794 – 1.12 0.489 170 1469 exclusion phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.778 0.57 – 1.06 0.113 51 429 exclusion phecode
371 Inflammation of the eye Sense Organs 0.938 0.875 – 1 0.0673 1061 7190 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.03 0.851 – 1.25 0.75 126 1173 exclusion phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.99 0.853 – 1.15 0.893 208 2101 exclusion phecode
371.21 Allergic conjunctivitis Sense Organs 0.966 0.82 – 1.14 0.681 171 1761 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.915 0.847 – 0.989 0.0255 827 5881 exclusion phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 1.04 0.759 – 1.43 0.796 45 323 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.03 0.899 – 1.17 0.708 270 2280 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.908 0.833 – 0.99 0.028 666 5197 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.813 0.659 – 1 0.0548 104 867 exclusion phecode
374.2 Lagophthalmos Sense Organs 1.12 0.868 – 1.45 0.382 71 518 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.959 0.834 – 1.1 0.55 248 2311 exclusion phecode
374.6 Dermatochalasis Sense Organs 0.919 0.786 – 1.07 0.29 193 2010 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.966 0.895 – 1.04 0.367 897 5809 exclusion phecode
375.1 Dry eyes Sense Organs 0.967 0.899 – 1.04 0.374 970 5921 exclusion phecode
375.2 Epiphora Sense Organs 0.928 0.752 – 1.15 0.486 109 943 exclusion phecode
376 Disorders of the orbit Sense Organs 1.04 0.819 – 1.31 0.765 85 816 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.09 0.93 – 1.27 0.295 187 2041 exclusion phecode
377.1 Optic atrophy Sense Organs 1.01 0.761 – 1.34 0.952 61 600 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.15 0.948 – 1.4 0.155 118 1325 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.14 1.01 – 1.29 0.0393 308 2832 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.13 0.966 – 1.31 0.128 195 1886 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.01 0.733 – 1.4 0.94 44 362 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.08 0.851 – 1.37 0.523 83 745 exclusion phecode
379 Other disorders of eye Sense Organs 0.955 0.891 – 1.02 0.188 1109 6488 exclusion phecode
379.1 Scleritis and episcleritis Sense Organs 0.84 0.597 – 1.18 0.316 45 414 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.923 0.85 – 1 0.0572 783 4805 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.703 0.477 – 1.04 0.0744 38 278 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.13 0.868 – 1.46 0.374 62 614 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.09 0.838 – 1.41 0.526 73 591 exclusion phecode
379.51 Pigmentary iris degeneration Sense Organs 0.638 0.346 – 1.18 0.151 18 138 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.908 0.793 – 1.04 0.165 268 2541 exclusion phecode
380 Disorders of external ear Sense Organs 0.93 0.846 – 1.02 0.135 533 4433 exclusion phecode
380.1 Otitis externa Sense Organs 0.889 0.785 – 1.01 0.0653 292 3392 exclusion phecode
380.4 Impacted cerumen Sense Organs 0.91 0.833 – 0.994 0.0367 622 5170 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.03 0.964 – 1.11 0.364 984 8885 exclusion phecode
381.1 Otitis media Sense Organs 1.05 0.967 – 1.14 0.249 692 7540 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.05 0.962 – 1.15 0.267 570 6551 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.957 0.864 – 1.06 0.395 456 4389 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 1.18 0.811 – 1.71 0.391 30 367 exclusion phecode
381.9 Otorrhea Sense Organs 1.36 1.07 – 1.72 0.0129 82 892 exclusion phecode
382 Otalgia Sense Organs 1.01 0.919 – 1.12 0.775 473 4795 exclusion phecode
383 Otosclerosis Sense Organs 1.06 0.746 – 1.5 0.75 33 289 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.03 0.846 – 1.24 0.799 126 1334 exclusion phecode
384.1 Myringitis Sense Organs 0.697 0.369 – 1.32 0.266 13 126 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.03 0.83 – 1.28 0.792 100 1050 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.954 0.783 – 1.16 0.645 115 1063 exclusion phecode
385.3 Cholesteatoma Sense Organs 0.959 0.755 – 1.22 0.734 77 704 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.01 0.722 – 1.42 0.95 42 313 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.964 0.864 – 1.08 0.515 389 4144 exclusion phecode
386.1 Meniere's disease Sense Organs 1.03 0.791 – 1.34 0.836 69 699 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.945 0.836 – 1.07 0.365 313 3465 exclusion phecode
386.21 Central origin vertigo Sense Organs 0.938 0.815 – 1.08 0.369 239 2681 exclusion phecode
386.3 Labyrinthitis Sense Organs 0.951 0.841 – 1.08 0.423 305 3323 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.01 0.957 – 1.07 0.656 1533 8939 exclusion phecode
388 Other disorders of ear Sense Organs 1.08 0.933 – 1.24 0.311 235 2220 exclusion phecode
389 Hearing loss Sense Organs 1.01 0.96 – 1.07 0.608 1750 9108 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.976 0.904 – 1.05 0.526 866 6253 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.08 0.935 – 1.24 0.304 231 2287 exclusion phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.965 0.676 – 1.38 0.843 45 353 exclusion phecode
389.4 Tinnitus Sense Organs 1.01 0.916 – 1.11 0.899 536 4740 exclusion phecode
389.5 Disorders of acoustic nerve Sense Organs 1.19 0.825 – 1.71 0.355 35 268 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.14 1 – 1.29 0.0439 313 2691 exclusion phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 1.01 0.779 – 1.32 0.921 71 628 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.09 0.878 – 1.34 0.446 103 958 exclusion phecode
394.3 Aortic valve disease Circulatory System 0.904 0.602 – 1.36 0.627 25 304 exclusion phecode
394.4 Acute rheumatic heart disease Circulatory System 0.994 0.564 – 1.75 0.983 11 124 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.12 0.927 – 1.34 0.248 146 1151 exclusion phecode
395 Heart valve disorders Circulatory System 1.09 1.01 – 1.18 0.0197 885 6001 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.04 0.95 – 1.15 0.37 538 4304 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.22 1.09 – 1.37 0.000542 378 3214 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.04 0.843 – 1.28 0.722 121 1016 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.43 0.952 – 2.14 0.0848 29 245 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.11 0.947 – 1.29 0.205 205 2036 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.09 1.02 – 1.17 0.00841 1089 7743 exclusion phecode
401 Hypertension Circulatory System 1.17 1.11 – 1.23 4.08e-10 3346 7626 exclusion phecode
401.1 Essential hypertension Circulatory System 1.16 1.11 – 1.22 1.73e-09 3302 7627 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.32 1.2 – 1.45 1.67e-08 559 4287 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.06 0.87 – 1.29 0.563 115 1846 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.39 1.25 – 1.54 1.43e-09 433 3799 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.27 1.15 – 1.4 2.79e-06 489 4747 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.19 1.12 – 1.27 1.01e-07 1399 6875 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.05 0.863 – 1.29 0.602 114 1634 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.22 1.11 – 1.33 3.51e-05 581 4475 exclusion phecode
411.3 Angina pectoris Circulatory System 1.23 1.09 – 1.38 0.000525 351 3742 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.19 1.11 – 1.27 1.3e-06 1170 6026 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.08 0.705 – 1.66 0.717 22 310 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.21 1.13 – 1.31 4.47e-07 935 5489 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.12 0.881 – 1.41 0.364 78 862 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.16 1.06 – 1.28 0.00163 537 4888 exclusion phecode
414.2 ASCVD Circulatory System 1.08 0.877 – 1.34 0.461 105 1390 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.17 1.07 – 1.28 0.000481 568 6409 exclusion phecode
415.1 Acute pulmonary heart disease Circulatory System 1.16 1.03 – 1.31 0.0144 307 4016 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.17 1.03 – 1.32 0.0119 306 3996 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.25 1.11 – 1.4 0.00032 325 3624 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.25 1.04 – 1.51 0.0171 141 1459 exclusion phecode
416 Cardiomegaly Circulatory System 1.24 1.08 – 1.44 0.00322 223 2598 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.04 0.993 – 1.09 0.093 2663 8303 exclusion phecode
418.1 Precordial pain Circulatory System 1.03 0.905 – 1.18 0.618 257 2916 exclusion phecode
420 Carditis Circulatory System 1 0.887 – 1.13 0.995 325 3199 exclusion phecode
420.1 Myocarditis Circulatory System 1.39 0.849 – 2.29 0.19 16 212 exclusion phecode
420.2 Pericarditis Circulatory System 1.04 0.879 – 1.22 0.669 176 1693 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.11 0.799 – 1.54 0.541 43 368 exclusion phecode
420.22 Chronic pericarditis Circulatory System 0.984 0.601 – 1.61 0.949 21 235 exclusion phecode
420.3 Endocarditis Circulatory System 0.976 0.822 – 1.16 0.778 162 1555 exclusion phecode
425 Cardiomyopathy Circulatory System 1.14 1.02 – 1.27 0.0241 365 3873 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.13 1.01 – 1.27 0.0345 347 3682 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.89 0.603 – 1.31 0.556 30 393 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.33 0.884 – 2.01 0.17 26 421 exclusion phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.13 0.878 – 1.45 0.341 72 673 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.64 1.01 – 2.66 0.045 24 212 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.08 1.03 – 1.14 0.00345 2393 6433 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.07 0.937 – 1.22 0.319 282 2269 exclusion phecode
426.21 First degree AV block Circulatory System 0.985 0.835 – 1.16 0.855 184 1698 exclusion phecode
426.22 Mobitz II AV block Circulatory System 1.48 0.741 – 2.95 0.268 11 121 exclusion phecode
426.23 Second degree AV block Circulatory System 1.14 0.812 – 1.59 0.457 41 380 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 0.998 0.781 – 1.28 0.989 85 744 exclusion phecode
426.25 Other heart block Circulatory System 1.38 0.956 – 1.99 0.0855 38 337 exclusion phecode
426.3 Bundle branch block Circulatory System 1.07 0.955 – 1.2 0.237 378 2927 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.01 0.874 – 1.17 0.897 235 2178 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.14 0.948 – 1.36 0.166 152 1610 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.855 0.566 – 1.29 0.456 24 216 exclusion phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.09 1.03 – 1.15 0.0022 2072 6305 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.24 1.03 – 1.5 0.0256 137 1431 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.17 1.03 – 1.33 0.0146 305 2302 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.17 0.994 – 1.38 0.0585 189 1569 exclusion phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.24 1.04 – 1.49 0.0159 150 1374 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.05 1.01 – 1.1 0.0213 3759 6569 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.08 0.979 – 1.19 0.123 517 4083 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.05 0.935 – 1.18 0.412 360 3264 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.11 0.948 – 1.29 0.202 212 1952 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.05 0.969 – 1.14 0.225 880 4073 exclusion phecode
427.21 Atrial fibrillation Circulatory System 1.04 0.952 – 1.13 0.415 850 3984 exclusion phecode
427.22 Atrial flutter Circulatory System 0.978 0.853 – 1.12 0.744 270 2103 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.09 1.03 – 1.15 0.00324 1873 6497 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.951 0.755 – 1.2 0.666 89 1045 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.12 0.78 – 1.61 0.536 31 405 exclusion phecode
427.42 Cardiac arrest Circulatory System 0.899 0.698 – 1.16 0.412 76 797 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.04 0.978 – 1.11 0.209 1413 6465 exclusion phecode
427.6 Premature beats Circulatory System 0.911 0.819 – 1.01 0.0869 451 3494 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 0.975 0.811 – 1.17 0.788 144 1322 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.16 1.08 – 1.24 1.15e-05 1198 6476 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.989 0.836 – 1.17 0.898 174 1536 exclusion phecode
427.9 Palpitations Circulatory System 0.934 0.871 – 1 0.0571 1079 6085 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.18 1.08 – 1.28 0.000215 692 5011 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.17 1.06 – 1.28 0.00097 592 4695 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.22 1.11 – 1.34 4.68e-05 568 4489 exclusion phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.24 1.09 – 1.41 0.000739 312 2812 exclusion phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.24 1.07 – 1.45 0.00411 207 2667 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.07 1.02 – 1.12 0.00453 2642 8036 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.18 1.02 – 1.35 0.0223 243 2297 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.13 1.06 – 1.21 0.000407 1140 6729 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.06 1.01 – 1.12 0.0209 2144 7990 exclusion phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.19 0.986 – 1.44 0.0702 123 1402 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.1 0.933 – 1.29 0.264 183 1622 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.24 0.934 – 1.64 0.137 60 542 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.14 0.901 – 1.44 0.275 87 759 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.11 0.856 – 1.43 0.441 73 525 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.1 1.03 – 1.18 0.00628 1116 6795 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.09 0.979 – 1.21 0.115 418 3096 exclusion phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.02 0.771 – 1.34 0.906 60 505 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 0.907 0.543 – 1.52 0.71 16 154 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.16 1.05 – 1.28 0.00301 482 4311 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.17 1.06 – 1.29 0.0026 467 4173 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.05 0.952 – 1.15 0.347 558 4590 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.07 0.966 – 1.18 0.201 483 4143 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.08 0.885 – 1.32 0.443 123 1079 exclusion phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.02 0.799 – 1.3 0.89 76 904 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.06 0.888 – 1.27 0.502 139 1421 exclusion phecode
440 Atherosclerosis Circulatory System 1.17 1.06 – 1.3 0.00165 483 3834 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.02 0.752 – 1.38 0.915 53 473 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.08 0.954 – 1.23 0.217 289 2602 exclusion phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.37 1.03 – 1.83 0.0306 57 444 exclusion phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.01 0.868 – 1.17 0.904 202 1833 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.21 1.01 – 1.44 0.036 146 1519 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.21 1.01 – 1.45 0.042 141 1086 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.06 0.807 – 1.38 0.688 64 493 exclusion phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.17 0.862 – 1.59 0.316 49 341 exclusion phecode
442 Other aneurysm Circulatory System 1.13 1.03 – 1.25 0.00851 538 4204 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.12 1 – 1.26 0.0469 359 3044 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.03 0.892 – 1.19 0.677 231 1842 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.03 0.69 – 1.52 0.901 26 331 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.38 0.941 – 2.02 0.0994 26 317 exclusion phecode
442.4 Arterial dissection Circulatory System 0.839 0.604 – 1.17 0.297 41 360 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.13 0.902 – 1.41 0.288 97 829 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.12 1.03 – 1.22 0.00568 751 5181 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.02 0.892 – 1.16 0.784 299 1780 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.6 1.04 – 2.48 0.0337 25 321 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.16 1.06 – 1.26 0.00134 633 4524 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.2 1.09 – 1.33 0.00029 470 3653 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.19 1.02 – 1.38 0.0244 205 1687 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.14 0.902 – 1.44 0.27 85 563 exclusion phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 0.921 0.641 – 1.32 0.656 33 254 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.1 0.895 – 1.34 0.375 112 996 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.905 0.615 – 1.33 0.615 29 233 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.36 0.789 – 2.35 0.266 17 155 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.07 0.839 – 1.37 0.573 74 611 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.16 1.05 – 1.27 0.00221 541 4593 exclusion phecode
447.1 Stricture of artery Circulatory System 1.12 0.926 – 1.36 0.241 127 1103 exclusion phecode
447.7 Aortic ectasia Circulatory System 1.12 0.913 – 1.37 0.28 110 1448 exclusion phecode
448 Disease of capillaries Circulatory System 0.826 0.733 – 0.932 0.00187 338 2641 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.09 0.981 – 1.21 0.11 431 4714 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.924 0.778 – 1.1 0.372 154 1664 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.886 0.621 – 1.27 0.508 39 565 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1.08 1.01 – 1.16 0.0329 915 7002 exclusion phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1.02 0.724 – 1.43 0.915 32 571 exclusion phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1.08 0.993 – 1.18 0.0729 596 6075 exclusion phecode
452.8 Postphlebitic syndrome Circulatory System 0.69 0.431 – 1.1 0.122 21 348 exclusion phecode
453 Chronic venous hypertension Circulatory System 0.812 0.584 – 1.13 0.216 47 476 exclusion phecode
454 Varicose veins Circulatory System 1.01 0.929 – 1.11 0.744 608 5675 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1.01 0.917 – 1.11 0.834 514 4894 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.965 0.853 – 1.09 0.57 316 3463 exclusion phecode
455 Hemorrhoids Circulatory System 0.953 0.895 – 1.02 0.142 1282 6964 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.977 0.892 – 1.07 0.618 567 5684 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.08 0.963 – 1.21 0.193 364 3134 exclusion phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.04 0.784 – 1.39 0.767 55 598 exclusion phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.07 0.95 – 1.2 0.273 336 2996 exclusion phecode
458 Hypotension Circulatory System 1.24 1.16 – 1.32 1.74e-10 1176 7346 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.25 1.1 – 1.41 0.000371 332 2790 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.25 1.08 – 1.43 0.00229 240 2177 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.25 1.17 – 1.34 2.24e-10 1063 7007 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.11 1.04 – 1.18 0.000716 1488 8249 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.08 0.918 – 1.27 0.361 198 1796 exclusion phecode
459.7 Blood vessel replaced Circulatory System 1.18 1.03 – 1.34 0.0177 270 2697 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.09 1.02 – 1.16 0.01 1216 7763 exclusion phecode
464 Acute sinusitis Respiratory 1 0.937 – 1.07 0.916 1058 7669 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.97 0.924 – 1.02 0.225 2314 8379 exclusion phecode
465.2 Acute pharyngitis Respiratory 0.96 0.903 – 1.02 0.184 1387 7845 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.01 0.811 – 1.26 0.933 99 1091 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.961 0.868 – 1.06 0.445 447 4242 exclusion phecode
471 Nasal polyps Respiratory 0.917 0.761 – 1.11 0.364 128 1347 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.919 0.823 – 1.03 0.131 386 4089 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.09 1.01 – 1.18 0.0291 765 5620 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.01 0.584 – 1.74 0.981 15 141 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.05 0.876 – 1.26 0.593 152 1442 exclusion phecode
473.4 Voice disturbance Respiratory 1.11 1.02 – 1.21 0.0171 621 4837 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1.09 0.958 – 1.24 0.195 289 2465 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.08 0.889 – 1.3 0.452 129 1165 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.06 0.923 – 1.23 0.395 220 2021 exclusion phecode
475 Chronic sinusitis Respiratory 1.02 0.948 – 1.09 0.625 987 6534 exclusion phecode
475.9 Postnasal drip Respiratory 0.913 0.78 – 1.07 0.257 196 1995 exclusion phecode
476 Allergic rhinitis Respiratory 0.968 0.924 – 1.01 0.17 2895 6585 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.18 1.04 – 1.34 0.0121 266 2574 exclusion phecode
478 Throat pain Respiratory 1.14 0.942 – 1.38 0.178 120 1024 exclusion phecode
479 Other upper respiratory disease Respiratory 1.07 1 – 1.13 0.0438 1311 6567 exclusion phecode
480 Pneumonia Respiratory 1.12 1.06 – 1.2 0.000199 1287 8722 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.17 1.04 – 1.32 0.00983 309 2487 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.28 1.07 – 1.53 0.00749 139 1193 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.32 0.96 – 1.82 0.0878 50 359 exclusion phecode
480.13 MRSA pneumonia Respiratory 1.64 0.975 – 2.77 0.0622 20 272 exclusion phecode
480.2 Viral pneumonia Respiratory 1.3 0.939 – 1.8 0.114 41 379 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.4 1.01 – 1.93 0.0404 47 332 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.44 1.01 – 2.06 0.0414 39 297 exclusion phecode
481 Influenza Respiratory 1.04 0.92 – 1.18 0.519 298 3205 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.978 0.898 – 1.07 0.614 646 7069 exclusion phecode
495 Asthma Respiratory 1.07 1.02 – 1.13 0.00918 1770 8173 exclusion phecode
495.1 Chronic obstructive asthma Respiratory 1.3 1 – 1.68 0.0483 66 857 exclusion phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 0.939 0.462 – 1.91 0.862 8 159 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.01 0.897 – 1.14 0.851 321 4419 exclusion phecode
496 Chronic airway obstruction Respiratory 1.29 1.21 – 1.38 4.92e-14 1192 6161 exclusion phecode
496.1 Emphysema Respiratory 1.33 1.21 – 1.46 3.96e-09 559 3825 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.38 1.28 – 1.49 2.69e-16 840 5653 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.42 1.3 – 1.53 4.89e-17 770 5285 exclusion phecode
496.3 Bronchiectasis Respiratory 1.15 0.971 – 1.36 0.105 170 1143 exclusion phecode
497 Bronchitis Respiratory 1.06 0.951 – 1.19 0.276 365 4623 exclusion phecode
498 Acute bronchospasm Respiratory 1.24 0.996 – 1.54 0.0548 97 1271 exclusion phecode
499 Cystic fibrosis Respiratory 1.3 0.973 – 1.73 0.0763 57 408 exclusion phecode
500 Lung disease due to external agents Respiratory 1.35 1.11 – 1.64 0.00299 122 1106 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.51 0.935 – 2.44 0.0917 23 203 exclusion phecode
500.2 Pneumoconiosis Respiratory 0.983 0.492 – 1.97 0.962 10 121 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.41 1.18 – 1.67 0.000102 173 1183 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.964 0.814 – 1.14 0.676 165 1637 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.23 1.05 – 1.46 0.0126 164 1657 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.995 0.817 – 1.21 0.961 126 1197 exclusion phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 0.9 0.684 – 1.18 0.452 66 623 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.13 1 – 1.27 0.0438 342 3215 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.18 1.09 – 1.28 8.14e-05 701 5222 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.17 1.08 – 1.28 0.000244 659 5524 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.18 1.07 – 1.31 0.000822 475 4713 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.2 1.11 – 1.3 3.19e-06 808 6265 exclusion phecode
509.1 Respiratory failure Respiratory 1.33 1.19 – 1.48 1.87e-07 427 3812 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.2 1.05 – 1.38 0.00626 269 2349 exclusion phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.18 1.06 – 1.32 0.00298 385 3241 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.25 1.1 – 1.41 0.000426 317 3416 exclusion phecode
510 Other diseases of lung Respiratory 1.06 0.992 – 1.13 0.0845 1194 7846 exclusion phecode
510.2 Lung transplant Respiratory 1.13 0.832 – 1.52 0.441 51 373 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.09 1.05 – 1.14 3.06e-05 3890 7132 exclusion phecode
512.1 Wheezing Respiratory 1.2 1.04 – 1.38 0.0134 215 3292 exclusion phecode
512.2 Painful respiration Respiratory 1.1 0.999 – 1.2 0.0524 552 5258 exclusion phecode
512.3 Abnormal chest sounds Respiratory 1.16 0.91 – 1.49 0.227 73 608 exclusion phecode
512.7 Shortness of breath Respiratory 1.14 1.08 – 1.2 4.29e-06 1926 7104 exclusion phecode
512.8 Cough Respiratory 1.06 1 – 1.11 0.0395 2033 7127 exclusion phecode
512.9 Other dyspnea Respiratory 1.1 1.04 – 1.16 0.000348 1997 7106 exclusion phecode
513 Respiratory abnormalities Respiratory 1.12 1.07 – 1.17 3.83e-06 2470 8537 exclusion phecode
513.3 Hypoventilation Respiratory 1.12 0.93 – 1.34 0.237 128 1878 exclusion phecode
513.31 Apnea Respiratory 1.15 0.906 – 1.46 0.251 76 960 exclusion phecode
513.32 Orthopnea Respiratory 1.16 0.792 – 1.69 0.449 28 412 exclusion phecode
513.4 Hyperventilation Respiratory 1.38 1.09 – 1.73 0.00699 94 1120 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.09 0.78 – 1.51 0.623 40 488 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.1 1.03 – 1.17 0.00488 1193 7434 exclusion phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 0.81 0.599 – 1.1 0.172 52 543 exclusion phecode
514.2 Solitary pulmonary nodule Respiratory 1.07 0.987 – 1.17 0.0977 652 5644 exclusion phecode
516 Abnormal sputum Respiratory 1.23 1.04 – 1.44 0.0145 169 1494 exclusion phecode
516.1 Hemoptysis Respiratory 1.22 1.02 – 1.47 0.0283 137 1263 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.08 1.02 – 1.15 0.00891 1418 9074 exclusion phecode
519.1 Tracheostomy complications Respiratory 1.65 1.25 – 2.18 0.000429 64 431 exclusion phecode
519.2 Respiratory complications Respiratory 1.08 0.87 – 1.33 0.5 94 928 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.06 0.952 – 1.19 0.274 382 3472 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.12 1.04 – 1.2 0.00129 1037 7618 exclusion phecode
520 Disorders of tooth development Digestive 0.978 0.809 – 1.18 0.816 120 952 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.13 0.829 – 1.55 0.432 52 380 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.945 0.752 – 1.19 0.625 77 638 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.46 1.27 – 1.67 4.15e-08 250 1935 exclusion phecode
521.1 Dental caries Digestive 1.43 1.25 – 1.65 4.38e-07 234 1781 exclusion phecode
521.2 Dental abrasion, erosion and attrition Digestive 0.983 0.537 – 1.8 0.956 8 116 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.37 1.13 – 1.67 0.00137 111 1178 exclusion phecode
522.5 Periapical abscess Digestive 1.52 1.23 – 1.88 8.92e-05 95 1040 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.28 1.08 – 1.52 0.00436 163 1547 exclusion phecode
523.1 Gingivitis Digestive 1.13 0.79 – 1.61 0.51 38 340 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.6 1.24 – 2.06 0.000331 71 779 exclusion phecode
523.31 Acute periodontitis Digestive 1.54 1.17 – 2.02 0.00196 56 663 exclusion phecode
523.32 Chronic periodontitis Digestive 1.75 1.15 – 2.67 0.00898 30 246 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.05 0.875 – 1.26 0.601 160 1055 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.06 0.85 – 1.31 0.623 110 683 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.37 1.21 – 1.56 1.1e-06 278 2423 exclusion phecode
525.1 Loss of teeth or edentulism Digestive 1.39 1.13 – 1.71 0.00206 105 894 exclusion phecode
526 Diseases of the jaws Digestive 1.07 0.987 – 1.15 0.104 817 6561 exclusion phecode
526.1 Cysts of the jaws Digestive 0.795 0.602 – 1.05 0.108 53 512 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.977 0.797 – 1.2 0.824 123 786 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.03 0.933 – 1.15 0.523 453 3884 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.03 0.916 – 1.15 0.654 371 3116 exclusion phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 1.01 0.876 – 1.16 0.891 237 2005 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 1.41 1.13 – 1.77 0.00248 104 654 exclusion phecode
526.8 Exostosis of jaw Digestive 1.5 0.887 – 2.54 0.13 21 98 exclusion phecode
526.9 Jaw disease NOS Digestive 1.13 0.956 – 1.33 0.155 173 1118 exclusion phecode
527 Diseases of the salivary glands Digestive 1.06 0.955 – 1.18 0.27 425 3834 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 0.883 0.499 – 1.56 0.667 14 141 exclusion phecode
527.2 Sialoadenitis Digestive 1.07 0.854 – 1.34 0.556 95 913 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.14 0.984 – 1.32 0.0812 226 1880 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.05 0.776 – 1.43 0.735 54 529 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.08 0.993 – 1.17 0.0742 751 5899 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.13 0.968 – 1.32 0.12 200 1559 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.28 0.949 – 1.72 0.106 51 490 exclusion phecode
528.12 Oral aphthae Digestive 0.96 0.744 – 1.24 0.757 69 559 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.81 1.39 – 2.34 7.32e-06 74 528 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.889 0.61 – 1.3 0.54 33 296 exclusion phecode
528.41 Cyst of the salivary gland Digestive 1.02 0.621 – 1.67 0.945 23 176 exclusion phecode
528.5 Diseases of lips Digestive 1.08 0.894 – 1.31 0.423 142 1063 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.1 0.759 – 1.6 0.613 34 277 exclusion phecode
528.7 Sialolithiasis Digestive 1.3 0.93 – 1.81 0.125 44 339 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 0.974 0.822 – 1.15 0.759 156 1409 exclusion phecode
529.1 Glossitis Digestive 1.29 0.884 – 1.9 0.185 30 268 exclusion phecode
529.6 Glossodynia Digestive 0.745 0.508 – 1.09 0.132 30 321 exclusion phecode
530 Diseases of esophagus Digestive 1.13 1.08 – 1.18 1.38e-07 3202 7330 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.12 1.07 – 1.18 5.8e-07 3046 7330 exclusion phecode
530.11 GERD Digestive 1.12 1.07 – 1.18 1.02e-06 2914 7329 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.16 0.915 – 1.46 0.224 84 907 exclusion phecode
530.13 Barrett's esophagus Digestive 1.36 1.11 – 1.66 0.00337 106 1472 exclusion phecode
530.14 Reflux esophagitis Digestive 1.13 1.01 – 1.27 0.0365 367 4224 exclusion phecode
530.15 Eosinophilic esophagitis Digestive 1.07 0.798 – 1.45 0.638 49 627 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.18 0.981 – 1.41 0.08 137 1353 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1.24 1.07 – 1.43 0.00468 217 2006 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.24 1.03 – 1.5 0.0237 131 1344 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.02 0.73 – 1.44 0.889 43 257 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.9 1.24 – 2.91 0.00319 22 185 exclusion phecode
530.9 Heartburn Digestive 1.12 0.994 – 1.27 0.0628 300 3782 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.15 1.04 – 1.28 0.00625 435 4455 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.2 0.947 – 1.52 0.131 81 733 exclusion phecode
531.2 Gastric ulcer Digestive 1.27 1.1 – 1.45 0.000699 247 2646 exclusion phecode
531.3 Duodenal ulcer Digestive 1.08 0.875 – 1.32 0.487 99 883 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.13 0.957 – 1.32 0.153 180 1724 exclusion phecode
531.5 Gastrojejunal ulcer Digestive 0.981 0.688 – 1.4 0.915 38 323 exclusion phecode
532 Dysphagia Digestive 1.27 1.19 – 1.35 1.28e-13 1388 6859 exclusion phecode
535 Gastritis and duodenitis Digestive 1.05 0.958 – 1.14 0.318 611 6299 exclusion phecode
535.1 Acute gastritis Digestive 1.18 1.03 – 1.36 0.017 238 2623 exclusion phecode
535.2 Atrophic gastritis Digestive 0.992 0.773 – 1.27 0.952 76 786 exclusion phecode
535.6 Duodenitis Digestive 0.877 0.672 – 1.14 0.333 67 710 exclusion phecode
535.8 Other specified gastritis Digestive 1.02 0.853 – 1.22 0.841 142 1439 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.01 0.889 – 1.14 0.909 294 2905 exclusion phecode
536 Disorders of function of stomach Digestive 1.13 1.05 – 1.22 0.00181 771 6521 exclusion phecode
536.3 Gastroparesis Digestive 1.22 1.04 – 1.43 0.0154 184 1584 exclusion phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.36 1.13 – 1.64 0.00136 137 858 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.11 1.01 – 1.22 0.026 544 4961 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.12 1.04 – 1.22 0.00359 746 6762 exclusion phecode
537.1 Lesions of stomach and duodenum Digestive 1.48 1.04 – 2.1 0.0273 34 309 exclusion phecode
539 Bariatric surgery Digestive 2.4 1.87 – 3.09 9.93e-12 73 3739 exclusion phecode
540 Appendiceal conditions Digestive 0.895 0.74 – 1.08 0.254 126 1222 exclusion phecode
540.1 Appendicitis Digestive 0.817 0.664 – 1 0.0542 110 1037 exclusion phecode
540.11 Acute appendicitis Digestive 0.791 0.632 – 0.991 0.0416 95 855 exclusion phecode
550 Abdominal hernia Digestive 1.01 0.949 – 1.08 0.712 1207 8816 exclusion phecode
550.1 Inguinal hernia Digestive 0.87 0.784 – 0.966 0.00905 445 3017 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.12 1.01 – 1.24 0.0323 446 5737 exclusion phecode
550.3 Femoral hernia Digestive 0.847 0.614 – 1.17 0.313 51 272 exclusion phecode
550.4 Umbilical hernia Digestive 0.909 0.768 – 1.08 0.267 155 2658 exclusion phecode
550.5 Ventral hernia Digestive 1.06 0.947 – 1.19 0.301 340 4744 exclusion phecode
550.6 Incisional hernia Digestive 1.07 0.915 – 1.25 0.4 177 2826 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.12 1.02 – 1.24 0.0223 466 3704 exclusion phecode
555.1 Regional enteritis Digestive 1.19 1.06 – 1.35 0.00431 313 2269 exclusion phecode
555.2 Ulcerative colitis Digestive 1.06 0.928 – 1.21 0.385 273 2180 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 0.993 0.84 – 1.18 0.939 175 1300 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.09 0.921 – 1.3 0.308 159 1371 exclusion phecode
556.1 Ulceration of intestine Digestive 1.08 0.899 – 1.29 0.422 139 1217 exclusion phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 1.3 0.923 – 1.82 0.134 40 393 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.23 1.1 – 1.37 0.000316 381 4374 exclusion phecode
557.1 Celiac disease Digestive 1.08 0.904 – 1.29 0.399 155 1065 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.12 1.04 – 1.2 0.00266 893 6442 exclusion phecode
559 Ileostomy status Digestive 1.14 0.994 – 1.31 0.06 248 2053 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.17 1.09 – 1.27 6.33e-05 792 5625 exclusion phecode
560.1 Paralytic ileus Digestive 1.12 1.01 – 1.26 0.0388 385 3274 exclusion phecode
560.2 Impaction of intestine Digestive 1.28 1.03 – 1.59 0.0235 111 930 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.17 0.928 – 1.48 0.181 90 613 exclusion phecode
560.4 Other intestinal obstruction Digestive 1.25 1.13 – 1.38 1.2e-05 482 3597 exclusion phecode
561 Symptoms involving digestive system Digestive 1.09 0.999 – 1.18 0.0533 672 5257 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1.01 0.935 – 1.08 0.86 1035 4936 exclusion phecode
562.1 Diverticulosis Digestive 1 0.929 – 1.08 0.982 1026 4925 exclusion phecode
562.2 Diverticulitis Digestive 1.13 0.983 – 1.29 0.0876 249 3143 exclusion phecode
564 Functional digestive disorders Digestive 1.11 1.06 – 1.17 8.23e-06 2747 6964 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.08 1.01 – 1.17 0.0361 904 5634 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.13 1.04 – 1.23 0.0031 685 5931 exclusion phecode
565 Anal and rectal conditions Digestive 1 0.928 – 1.08 0.966 818 6940 exclusion phecode
565.1 Anal and rectal polyp Digestive 0.934 0.811 – 1.07 0.339 236 2505 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.2 1.07 – 1.36 0.00245 336 2915 exclusion phecode
568 Other disorders of peritoneum Digestive 1.09 0.974 – 1.21 0.134 372 3676 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.15 1.01 – 1.31 0.039 262 2676 exclusion phecode
569 Other disorders of intestine Digestive 1.1 1.04 – 1.16 0.000957 1700 8326 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.18 0.909 – 1.52 0.216 81 697 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.23 1.09 – 1.39 0.000885 304 3101 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.15 1.06 – 1.25 0.000719 692 7454 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.14 1.05 – 1.25 0.00219 622 7333 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.25 1.07 – 1.47 0.00606 178 1964 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.3 0.933 – 1.82 0.121 38 370 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.17 1 – 1.36 0.0474 201 1842 exclusion phecode
571.81 Portal hypertension Digestive 1.11 0.901 – 1.37 0.327 106 1127 exclusion phecode
572 Ascites (non malignant) Digestive 1.14 1.04 – 1.25 0.0039 575 5073 exclusion phecode
573 Other disorders of liver Digestive 1.07 1 – 1.15 0.0394 1049 7805 exclusion phecode
573.1 Chronic passive congestion of liver Digestive 1.61 1.07 – 2.42 0.0233 33 296 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.06 0.83 – 1.36 0.637 71 550 exclusion phecode
573.3 Hepatomegaly Digestive 1.21 0.977 – 1.5 0.0799 93 1082 exclusion phecode
573.4 Acute and subacute necrosis of liver Digestive 1.19 0.927 – 1.53 0.172 80 635 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.18 1.02 – 1.36 0.0265 232 1937 exclusion phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.11 1.01 – 1.22 0.0228 560 5842 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.09 0.996 – 1.19 0.0614 572 6092 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.13 1.06 – 1.22 0.000483 969 7954 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.12 1.02 – 1.23 0.0172 520 7209 exclusion phecode
574.1 Cholelithiasis Digestive 1.11 1.01 – 1.23 0.0378 455 6806 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.973 0.721 – 1.31 0.857 46 772 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.962 0.759 – 1.22 0.746 77 1290 exclusion phecode
574.2 Calculus of bile duct Digestive 1.1 0.931 – 1.31 0.257 161 1979 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.21 1.01 – 1.46 0.0356 137 1871 exclusion phecode
575 Other biliary tract disease Digestive 1.11 1.01 – 1.23 0.0274 496 5142 exclusion phecode
575.1 Cholangitis Digestive 1.13 0.914 – 1.4 0.257 101 731 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.2 1.02 – 1.41 0.0325 173 1349 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.718 0.518 – 0.996 0.047 40 529 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.07 0.908 – 1.26 0.412 170 2192 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.21 1.07 – 1.36 0.00288 302 2508 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.89 0.67 – 1.18 0.418 56 590 exclusion phecode
577 Diseases of pancreas Digestive 1.14 1.04 – 1.25 0.00534 554 4716 exclusion phecode
577.1 Acute pancreatitis Digestive 1.26 1.11 – 1.43 0.000328 285 2551 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.58 1.3 – 1.91 3.58e-06 138 982 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.07 0.897 – 1.29 0.435 158 1167 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.08 1.01 – 1.16 0.0236 1007 8632 exclusion phecode
578.1 Hematemesis Digestive 1.36 1.12 – 1.65 0.00183 117 1060 exclusion phecode
578.2 Blood in stool Digestive 1.1 1.01 – 1.2 0.0351 600 5938 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.02 0.921 – 1.12 0.749 476 5034 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.16 1.03 – 1.3 0.011 349 3224 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.11 1.04 – 1.19 0.00307 975 7967 exclusion phecode
579.2 Splenomegaly Digestive 1.16 0.964 – 1.41 0.115 121 1577 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.12 0.995 – 1.26 0.0608 326 3092 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.18 1.05 – 1.33 0.00632 327 3423 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.35 1.07 – 1.7 0.0116 93 846 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.43 0.973 – 2.09 0.0687 30 314 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.67 1.01 – 2.77 0.0458 17 241 exclusion phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.25 0.714 – 2.2 0.433 13 135 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.46 1.12 – 1.92 0.00597 71 621 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.12 0.806 – 1.55 0.502 37 466 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.23 1.07 – 1.41 0.00273 249 2607 exclusion phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.14 0.955 – 1.37 0.144 138 1500 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.39 1.16 – 1.65 0.000268 147 1449 exclusion phecode
580.4 Renal sclerosis, NOS Genitourinary 1.21 0.938 – 1.55 0.144 71 754 exclusion phecode
585 Renal failure Genitourinary 1.22 1.14 – 1.29 6.42e-10 1352 7675 exclusion phecode
585.1 Acute renal failure Genitourinary 1.27 1.18 – 1.38 1.14e-09 803 6037 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.27 1.09 – 1.49 0.00283 182 1711 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.23 1.15 – 1.33 6.86e-09 985 6716 exclusion phecode
585.31 Renal dialysis Genitourinary 1.32 1.13 – 1.55 0.000694 176 1530 exclusion phecode
585.32 End stage renal disease Genitourinary 1.41 1.23 – 1.62 1.32e-06 238 2054 exclusion phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.23 1.11 – 1.36 3.95e-05 492 4489 exclusion phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.25 1.07 – 1.46 0.00416 187 1901 exclusion phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.27 1.1 – 1.46 0.00112 232 2389 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.12 1.06 – 1.19 0.000165 1476 8474 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.1 0.874 – 1.39 0.407 86 891 exclusion phecode
586.11 Small kidney Genitourinary 1.17 0.849 – 1.61 0.337 45 515 exclusion phecode
586.12 Vesicoureteral reflux Genitourinary 0.962 0.709 – 1.31 0.804 40 401 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.04 0.912 – 1.19 0.541 257 2645 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.22 0.886 – 1.68 0.225 44 391 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.03 0.925 – 1.15 0.579 391 3829 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.26 1.09 – 1.45 0.00131 231 1742 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.4 1.21 – 1.62 5.19e-06 220 2000 exclusion phecode
588.1 Renal osteodystrophy Genitourinary 1.3 1.02 – 1.65 0.0311 85 582 exclusion phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.32 1.11 – 1.57 0.00137 155 1556 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.17 1.01 – 1.36 0.0398 210 2132 exclusion phecode
590 Pyelonephritis Genitourinary 1.09 0.965 – 1.23 0.17 326 3559 exclusion phecode
591 Urinary tract infection Genitourinary 0.996 0.947 – 1.05 0.87 2300 7506 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.05 0.97 – 1.14 0.22 740 5943 exclusion phecode
592.1 Cystitis Genitourinary 1.07 0.983 – 1.16 0.117 698 5747 exclusion phecode
592.11 Acute cystitis Genitourinary 1.09 0.975 – 1.21 0.134 421 4051 exclusion phecode
592.12 Chronic cystitis Genitourinary 1.11 0.812 – 1.52 0.516 49 587 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.05 0.873 – 1.27 0.586 139 1166 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.926 0.697 – 1.23 0.595 62 490 exclusion phecode
593 Hematuria Genitourinary 0.99 0.922 – 1.06 0.781 970 7381 exclusion phecode
593.1 Gross hematuria Genitourinary 0.958 0.843 – 1.09 0.51 285 2873 exclusion phecode
593.2 Microscopic hematuria Genitourinary 1.02 0.88 – 1.18 0.812 229 2282 exclusion phecode
594 Urinary calculus Genitourinary 1.08 1.01 – 1.15 0.0183 1206 9137 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.07 1 – 1.14 0.0463 1117 9085 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.08 0.852 – 1.37 0.525 80 715 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.01 0.876 – 1.15 0.942 234 3001 exclusion phecode
594.8 Renal colic Genitourinary 1.19 0.932 – 1.51 0.166 70 882 exclusion phecode
595 Hydronephrosis Genitourinary 1.19 1.06 – 1.32 0.00241 382 3817 exclusion phecode
596 Other disorders of bladder Genitourinary 0.981 0.902 – 1.07 0.655 673 5962 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.1 0.859 – 1.4 0.461 75 680 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1.01 0.903 – 1.13 0.87 381 3817 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1 0.88 – 1.14 0.974 278 2509 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.98 0.811 – 1.19 0.839 129 1171 exclusion phecode
597.2 Urinary complications NEC Genitourinary 0.955 0.824 – 1.11 0.543 217 2148 exclusion phecode
597.8 Urethral hypermobility/ISD Genitourinary 1 0.726 – 1.39 0.978 40 454 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.72 1.09 – 2.73 0.0207 25 281 exclusion phecode
598.4 Other cells and casts in urine Genitourinary 1.53 0.962 – 2.43 0.0723 23 247 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.987 0.944 – 1.03 0.582 3011 7568 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.76 0.627 – 0.921 0.00516 132 1245 exclusion phecode
599.2 Retention of urine Genitourinary 1.01 0.946 – 1.09 0.696 1038 6664 exclusion phecode
599.3 Dysuria Genitourinary 0.961 0.898 – 1.03 0.26 1049 6736 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.966 0.899 – 1.04 0.355 972 6365 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 0.967 0.903 – 1.03 0.331 1105 6871 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.15 0.959 – 1.38 0.131 142 1204 exclusion phecode
599.7 Urethral discharge Genitourinary 1.08 0.679 – 1.71 0.749 18 194 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 0.958 0.895 – 1.03 0.218 1114 6590 exclusion phecode
599.9 Other abnormality of urination Genitourinary 0.917 0.84 – 1 0.0514 621 5727 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.887 0.801 – 0.983 0.0216 641 1750 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 0.933 0.787 – 1.11 0.428 157 1631 exclusion phecode
601.1 Prostatitis Genitourinary 0.856 0.666 – 1.1 0.222 76 724 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.916 0.61 – 1.37 0.671 31 199 exclusion phecode
601.12 Chronic prostatitis Genitourinary 0.857 0.444 – 1.65 0.646 12 142 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.901 0.692 – 1.17 0.442 61 681 exclusion phecode
601.4 Balanoposthitis Genitourinary 1.43 0.832 – 2.45 0.196 13 226 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.04 0.686 – 1.57 0.858 23 286 exclusion phecode
602 Other disorders of prostate Genitourinary 0.989 0.752 – 1.3 0.935 67 483 exclusion phecode
602.3 Dysplasia of prostate Genitourinary 1.58 0.827 – 3.02 0.166 15 93 exclusion phecode
603 Other disorders of testis Genitourinary 1.08 0.869 – 1.34 0.494 86 836 exclusion phecode
603.1 Hydrocele Genitourinary 0.939 0.698 – 1.26 0.675 47 521 exclusion phecode
603.2 Spermatocele Genitourinary 1.05 0.754 – 1.47 0.76 40 283 exclusion phecode
604 Disorders of penis Genitourinary 1.01 0.846 – 1.21 0.892 133 1209 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.32 0.816 – 2.13 0.26 16 263 exclusion phecode
604.3 Peyronie's disease Genitourinary 0.962 0.707 – 1.31 0.802 48 330 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.873 0.787 – 0.968 0.0101 496 2198 exclusion phecode
608 Other disorders of male genital organs Genitourinary 0.919 0.816 – 1.03 0.164 317 2629 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.945 0.755 – 1.18 0.624 77 860 exclusion phecode
609.1 Infertility, male Genitourinary 0.934 0.721 – 1.21 0.604 56 653 exclusion phecode
609.11 Azoospermia and oligospermia Genitourinary 1.28 0.793 – 2.06 0.314 14 230 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.864 0.578 – 1.29 0.475 24 295 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.903 0.841 – 0.969 0.00483 1103 4593 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.907 0.821 – 1 0.0556 506 3675 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 0.632 0.383 – 1.04 0.0733 19 147 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.901 0.834 – 0.974 0.00855 879 4543 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.898 0.802 – 1.01 0.0615 390 3126 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.902 0.851 – 0.957 0.000596 1789 4939 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.88 0.825 – 0.938 8.82e-05 1489 4263 exclusion phecode
611.11 Mammographic microcalcification Genitourinary 0.882 0.783 – 0.994 0.039 364 2535 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.913 0.851 – 0.979 0.0107 1089 4931 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.901 0.782 – 1.04 0.152 232 2773 exclusion phecode
612.1 Galactorrhea Genitourinary 0.847 0.592 – 1.21 0.361 34 435 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.989 0.824 – 1.19 0.908 135 2033 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 0.605 0.409 – 0.895 0.0119 36 230 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.933 0.871 – 0.998 0.0444 1132 5978 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 0.877 0.738 – 1.04 0.135 152 1564 exclusion phecode
613.5 Mastodynia Genitourinary 1.02 0.925 – 1.13 0.663 489 4210 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.858 0.751 – 0.981 0.0245 269 2329 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 0.865 0.759 – 0.986 0.0299 273 2469 exclusion phecode
613.9 Breast disorder NOS Genitourinary 0.953 0.857 – 1.06 0.38 424 3595 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.991 0.925 – 1.06 0.807 1089 5485 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1 0.79 – 1.27 0.979 84 897 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.975 0.81 – 1.17 0.787 140 1356 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.882 0.588 – 1.32 0.546 31 282 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.943 0.709 – 1.26 0.69 61 500 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.835 0.646 – 1.08 0.165 72 687 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1 0.745 – 1.35 0.992 52 476 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.982 0.913 – 1.06 0.638 944 5450 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.05 0.81 – 1.35 0.732 71 767 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.984 0.91 – 1.06 0.678 820 5315 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.39 0.959 – 2 0.0821 37 368 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.878 0.665 – 1.16 0.36 59 631 exclusion phecode
615 Endometriosis Genitourinary 1 0.903 – 1.11 0.968 433 3999 exclusion phecode
618 Genital prolapse Genitourinary 0.964 0.874 – 1.06 0.469 508 4723 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.941 0.835 – 1.06 0.316 345 3445 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.958 0.8 – 1.15 0.638 145 1379 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.972 0.753 – 1.26 0.828 73 757 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.969 0.779 – 1.21 0.779 103 1118 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1.01 0.948 – 1.07 0.864 1658 5216 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.93 0.827 – 1.04 0.219 344 3480 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 1.01 0.849 – 1.19 0.936 154 1622 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.924 0.778 – 1.1 0.372 163 1311 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.02 0.94 – 1.11 0.636 760 5121 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.02 0.903 – 1.15 0.765 326 3206 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1.11 0.916 – 1.35 0.279 118 1063 exclusion phecode
620.1 Dysplasia of cervix Genitourinary 1.01 0.769 – 1.34 0.918 57 513 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.874 0.671 – 1.14 0.315 63 1163 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.863 0.769 – 0.969 0.0124 353 3805 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.841 0.735 – 0.962 0.0117 258 2965 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 0.86 0.706 – 1.05 0.134 123 1162 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 0.966 0.835 – 1.12 0.642 220 2246 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 1.03 0.932 – 1.15 0.526 437 3600 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 1.03 0.772 – 1.37 0.852 55 525 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 1.28 0.821 – 1.98 0.278 28 159 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.916 0.82 – 1.02 0.123 388 3990 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.95 0.895 – 1.01 0.0934 1668 4852 exclusion phecode
625.1 Dyspareunia Genitourinary 0.919 0.823 – 1.03 0.132 405 3480 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.961 0.904 – 1.02 0.201 1676 4395 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.935 0.873 – 1 0.0537 1227 4097 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 1.06 0.938 – 1.2 0.34 304 2629 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 0.932 0.846 – 1.03 0.148 547 3486 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.919 0.835 – 1.01 0.0838 552 3582 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.911 0.798 – 1.04 0.164 278 2647 exclusion phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.844 0.687 – 1.04 0.107 108 1134 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.987 0.884 – 1.1 0.812 408 3005 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.976 0.783 – 1.22 0.829 99 955 exclusion phecode
626.8 Infertility, female Genitourinary 0.902 0.788 – 1.03 0.134 255 2068 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.92 0.859 – 0.986 0.0183 1243 3886 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 0.886 0.774 – 1.01 0.0769 277 2549 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.939 0.865 – 1.02 0.128 834 3588 exclusion phecode
627.21 Symptomatic artificial menopause Genitourinary 0.768 0.535 – 1.1 0.154 40 402 exclusion phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.833 0.672 – 1.03 0.0949 113 855 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.852 0.749 – 0.969 0.0149 314 2315 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1 0.793 – 1.26 0.998 91 963 exclusion phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.814 0.663 – 0.999 0.0491 118 838 exclusion phecode
628 Ovarian cyst Genitourinary 0.93 0.845 – 1.02 0.14 539 3925 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.08 0.939 – 1.23 0.291 244 2293 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.991 0.785 – 1.25 0.94 90 772 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.9 0.623 – 1.3 0.577 30 347 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.908 0.775 – 1.07 0.238 183 1632 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.886 0.729 – 1.08 0.221 122 1112 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.961 0.764 – 1.21 0.737 88 909 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.953 0.848 – 1.07 0.411 351 2386 exclusion phecode
636.1 Threatened premature labor Pregnancy Complications 1.05 0.873 – 1.27 0.587 131 1173 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 1.01 0.804 – 1.27 0.937 92 869 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.907 0.755 – 1.09 0.298 132 1359 exclusion phecode
636.8 Cervical incompetence Pregnancy Complications 1.26 0.812 – 1.96 0.303 22 245 exclusion phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.22 0.784 – 1.9 0.377 20 240 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.883 0.734 – 1.06 0.188 129 1768 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.931 0.717 – 1.21 0.595 66 885 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.936 0.729 – 1.2 0.608 71 800 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.826 0.583 – 1.17 0.28 35 368 exclusion phecode
644 Anemia during pregnancy Pregnancy Complications 1.04 0.804 – 1.35 0.756 69 747 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.997 0.864 – 1.15 0.971 227 2138 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.07 0.831 – 1.37 0.614 75 655 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.936 0.711 – 1.23 0.637 63 712 exclusion phecode
647.3 Major puerperal infection Pregnancy Complications 0.81 0.486 – 1.35 0.419 20 204 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.974 0.867 – 1.09 0.65 367 2532 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.976 0.807 – 1.18 0.801 124 1610 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.06 0.894 – 1.25 0.514 163 1713 exclusion phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.945 0.708 – 1.26 0.701 54 637 exclusion phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 0.888 0.684 – 1.15 0.375 65 637 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.948 0.86 – 1.05 0.291 514 3055 exclusion phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 0.952 0.812 – 1.12 0.542 188 1757 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.96 0.839 – 1.1 0.556 253 2170 exclusion phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 0.816 0.419 – 1.59 0.549 5 144 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.984 0.86 – 1.12 0.808 266 2143 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.21 0.92 – 1.6 0.17 64 707 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.969 0.699 – 1.34 0.85 44 543 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.794 0.604 – 1.04 0.0981 63 580 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.18 1.11 – 1.25 1.4e-07 1331 9223 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.03 0.903 – 1.18 0.654 259 2612 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.23 1.07 – 1.42 0.00453 224 2219 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.27 1.14 – 1.41 1.88e-05 397 4472 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.22 1.1 – 1.35 0.000266 406 4641 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.29 1.14 – 1.45 3.43e-05 330 3685 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.18 1.04 – 1.34 0.0115 285 3560 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.03 0.931 – 1.13 0.588 485 4893 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 0.968 0.796 – 1.18 0.749 114 1391 exclusion phecode
686.2 Impetigo Dermatologic 1.09 0.878 – 1.36 0.423 102 1017 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.19 0.834 – 1.7 0.337 28 403 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.03 0.731 – 1.46 0.856 34 380 exclusion phecode
686.5 Pyoderma Dermatologic 1.76 0.812 – 3.82 0.152 8 144 exclusion phecode
687 Symptoms affecting skin Dermatologic 0.941 0.848 – 1.04 0.255 449 3752 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.985 0.931 – 1.04 0.601 1623 8190 exclusion phecode
687.3 Changes in skin texture Dermatologic 1.02 0.802 – 1.29 0.898 85 837 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.01 0.948 – 1.07 0.823 1359 8010 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.918 0.873 – 0.965 0.000743 2241 8716 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.895 0.837 – 0.956 0.00102 1200 6764 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.894 0.836 – 0.955 0.000931 1200 6752 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.98 0.809 – 1.19 0.832 123 1322 exclusion phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 1.17 0.743 – 1.83 0.503 21 163 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.894 0.81 – 0.986 0.0248 500 4084 exclusion phecode
694.1 Vitiligo Dermatologic 1.55 1.08 – 2.23 0.0186 37 300 exclusion phecode
694.2 Other dyschromia Dermatologic 0.856 0.771 – 0.95 0.00339 447 3711 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.28 0.798 – 2.07 0.304 24 163 exclusion phecode
695 Erythematous conditions Dermatologic 0.977 0.906 – 1.05 0.555 844 6904 exclusion phecode
695.1 Toxic erythema Dermatologic 0.694 0.384 – 1.25 0.226 15 173 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.23 0.75 – 2.02 0.412 20 172 exclusion phecode
695.3 Rosacea Dermatologic 0.818 0.73 – 0.917 0.000542 366 3953 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.19 1.01 – 1.41 0.0352 185 1711 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.1 0.845 – 1.44 0.469 67 616 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.17 0.993 – 1.39 0.0606 177 1613 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 1.09 0.89 – 1.33 0.409 113 1324 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 0.983 0.803 – 1.2 0.871 105 1866 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.799 0.465 – 1.37 0.417 15 165 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.1 0.915 – 1.31 0.317 132 1504 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.949 0.835 – 1.08 0.428 275 3123 exclusion phecode
696.3 Pityriasis Dermatologic 0.867 0.6 – 1.25 0.45 36 277 exclusion phecode
696.4 Psoriasis Dermatologic 0.981 0.855 – 1.13 0.786 238 2876 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.96 0.834 – 1.11 0.573 222 2603 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.806 0.578 – 1.12 0.203 41 615 exclusion phecode
697 Sarcoidosis Dermatologic 1.05 0.783 – 1.42 0.727 47 653 exclusion phecode
698 Pruritus and related conditions Dermatologic 0.957 0.873 – 1.05 0.351 557 5421 exclusion phecode
700 Corns and callosities Dermatologic 0.95 0.823 – 1.1 0.486 229 2355 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.944 0.894 – 0.998 0.0404 1735 9024 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.983 0.822 – 1.18 0.854 141 1181 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.969 0.887 – 1.06 0.478 623 5144 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 1.06 0.878 – 1.29 0.531 133 1404 exclusion phecode
701.4 Keloid scar Dermatologic 0.986 0.83 – 1.17 0.873 158 1531 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 0.996 0.8 – 1.24 0.971 91 904 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.88 0.828 – 0.934 3.18e-05 1588 6196 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.816 0.756 – 0.879 1.07e-07 950 5238 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.891 0.835 – 0.951 0.000506 1277 6486 exclusion phecode
702.4 Degenerative skin disorders Dermatologic 1.27 0.787 – 2.04 0.33 25 197 exclusion phecode
703 Diseases of nail, NOS Dermatologic 0.963 0.856 – 1.08 0.528 333 3307 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.933 0.792 – 1.1 0.41 167 1978 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.914 0.845 – 0.988 0.0239 765 7325 exclusion phecode
704.1 Alopecia Dermatologic 0.878 0.788 – 0.978 0.0179 409 3630 exclusion phecode
704.11 Alopecia Areata Dermatologic 1.14 0.722 – 1.81 0.567 21 179 exclusion phecode
704.12 Telogen effluvium Dermatologic 0.785 0.481 – 1.28 0.331 22 160 exclusion phecode
704.2 Hirsutism Dermatologic 1.16 0.857 – 1.57 0.335 45 882 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.965 0.864 – 1.08 0.531 375 3901 exclusion phecode
705 Disorders of sweat glands Dermatologic 0.9 0.743 – 1.09 0.279 115 1541 exclusion phecode
705.1 Dyshidrosis Dermatologic 0.647 0.429 – 0.976 0.0378 33 340 exclusion phecode
705.3 Hidradenitis Dermatologic 1.01 0.724 – 1.41 0.947 33 639 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1 0.88 – 1.15 0.951 263 2649 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 0.892 0.842 – 0.945 8.96e-05 1531 9248 exclusion phecode
706.1 Acne Dermatologic 0.856 0.793 – 0.924 6.24e-05 832 5978 exclusion phecode
706.2 Sebaceous cyst Dermatologic 0.912 0.837 – 0.994 0.035 644 6019 exclusion phecode
706.3 Seborrhea Dermatologic 0.724 0.416 – 1.26 0.254 16 137 exclusion phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.909 0.806 – 1.03 0.122 322 3244 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.19 1.09 – 1.3 7.87e-05 597 5738 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.27 1.09 – 1.48 0.00182 206 1652 exclusion phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.24 1.06 – 1.45 0.00671 180 1928 exclusion phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1.17 1.05 – 1.31 0.00572 356 3547 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.994 0.89 – 1.11 0.922 383 3529 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.03 0.856 – 1.24 0.753 132 1192 exclusion phecode
709.3 Systemic sclerosis Dermatologic 0.927 0.723 – 1.19 0.551 72 515 exclusion phecode
709.5 Dermatomyositis Dermatologic 0.944 0.601 – 1.48 0.802 18 210 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.42 0.919 – 2.2 0.114 27 213 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.04 0.902 – 1.2 0.592 239 2277 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.3 1.14 – 1.47 6.84e-05 282 2616 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.3 1.14 – 1.49 6.99e-05 275 2462 exclusion phecode
710.11 Acute osteomyelitis Musculoskeletal 1.38 1.13 – 1.67 0.00121 130 1196 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.26 1.04 – 1.54 0.0191 126 1049 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.35 1.18 – 1.55 1.13e-05 258 2362 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 0.854 0.663 – 1.1 0.221 77 883 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.02 0.746 – 1.4 0.901 46 610 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.17 0.82 – 1.68 0.383 31 400 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.19 0.915 – 1.55 0.194 62 642 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.72 1.08 – 2.73 0.0216 20 304 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.12 1.02 – 1.25 0.0236 468 4438 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.19 1.06 – 1.33 0.00269 386 3663 exclusion phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.18 0.823 – 1.68 0.371 33 237 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.11 0.967 – 1.27 0.137 244 2802 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.03 0.777 – 1.36 0.84 57 676 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.16 0.872 – 1.55 0.304 50 545 exclusion phecode
716 Other arthropathies Musculoskeletal 1.06 1 – 1.11 0.0323 2506 7939 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.09 0.758 – 1.56 0.652 33 432 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.807 0.508 – 1.28 0.365 20 272 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.06 1.01 – 1.11 0.0271 2492 7936 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.972 0.722 – 1.31 0.849 52 562 exclusion phecode
720 Spinal stenosis Musculoskeletal 1.08 0.992 – 1.18 0.0768 649 6151 exclusion phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1.1 0.991 – 1.22 0.0721 428 4881 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1.07 1 – 1.15 0.0421 1075 7226 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.07 1 – 1.15 0.0499 1008 7068 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.19 1 – 1.42 0.0476 152 1737 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 0.869 0.62 – 1.22 0.415 40 562 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.09 1.02 – 1.16 0.00722 1199 8037 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.11 1.02 – 1.2 0.0186 659 7186 exclusion phecode
722.3 Schmorl's nodes Musculoskeletal 0.856 0.583 – 1.26 0.427 32 264 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.09 1 – 1.18 0.0405 752 6798 exclusion phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.35 1.07 – 1.7 0.01 92 1084 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.21 0.929 – 1.56 0.16 73 827 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.997 0.89 – 1.12 0.961 370 4256 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.03 0.897 – 1.19 0.643 230 2233 exclusion phecode
723.1 Torticollis Musculoskeletal 1.01 0.772 – 1.33 0.928 62 589 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.03 0.96 – 1.11 0.394 890 7601 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1.03 0.935 – 1.13 0.575 520 5376 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.871 0.703 – 1.08 0.205 98 1021 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.13 0.959 – 1.32 0.146 175 2182 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.1 0.971 – 1.25 0.131 288 3198 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.957 0.909 – 1.01 0.099 2111 7342 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.966 0.912 – 1.02 0.244 1605 7313 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.925 0.786 – 1.09 0.345 173 2098 exclusion phecode
726.3 Bursitis Musculoskeletal 0.897 0.8 – 1.01 0.0656 359 3818 exclusion phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.942 0.817 – 1.08 0.403 228 2653 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.01 0.953 – 1.07 0.741 1618 7309 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.02 0.942 – 1.11 0.577 681 6062 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.968 0.752 – 1.24 0.798 80 907 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.983 0.873 – 1.11 0.77 347 3217 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 1.06 0.847 – 1.33 0.603 89 1092 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.96 0.864 – 1.07 0.447 420 4585 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.16 0.988 – 1.37 0.0686 167 1482 exclusion phecode
727.8 Plica syndrome Musculoskeletal 0.881 0.651 – 1.19 0.413 50 385 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1 0.935 – 1.08 0.923 988 7020 exclusion phecode
728.1 Muscular calcification and ossification Musculoskeletal 1.19 0.763 – 1.86 0.443 22 186 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.04 0.825 – 1.31 0.748 77 712 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.876 0.793 – 0.967 0.00891 473 5331 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.794 0.642 – 0.983 0.0339 108 781 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.1 1.01 – 1.2 0.0252 669 6222 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.23 0.766 – 1.97 0.393 19 168 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.939 0.51 – 1.73 0.84 9 304 exclusion phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 0.972 0.61 – 1.55 0.905 21 155 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.29 0.921 – 1.82 0.137 36 353 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.966 0.772 – 1.21 0.763 91 1000 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.954 0.668 – 1.36 0.794 40 530 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.02 0.661 – 1.58 0.918 24 265 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.985 0.922 – 1.05 0.653 1259 6039 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.2 0.895 – 1.62 0.219 53 452 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.17 0.985 – 1.4 0.0732 160 1061 exclusion phecode
733.6 Costochondritis Musculoskeletal 1.1 0.87 – 1.39 0.428 79 878 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.31 1.13 – 1.52 0.000458 207 1900 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.11 0.758 – 1.63 0.588 33 261 exclusion phecode
735 Acquired foot deformities Musculoskeletal 0.959 0.886 – 1.04 0.305 762 6663 exclusion phecode
735.1 Flat foot Musculoskeletal 0.79 0.643 – 0.97 0.0246 109 1399 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 0.995 0.872 – 1.14 0.942 279 2535 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.07 0.901 – 1.28 0.426 160 1562 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 1.02 0.818 – 1.27 0.869 103 848 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.895 0.795 – 1.01 0.0675 348 3312 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 0.933 0.854 – 1.02 0.122 614 6048 exclusion phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.939 0.642 – 1.37 0.745 32 220 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.05 0.793 – 1.39 0.74 66 463 exclusion phecode
736.3 Acquired deformities of hip Musculoskeletal 1.01 0.587 – 1.75 0.961 16 188 exclusion phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 1.04 0.767 – 1.4 0.812 48 682 exclusion phecode
736.5 Acquired deformities of knee Musculoskeletal 0.916 0.644 – 1.3 0.623 32 499 exclusion phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.933 0.733 – 1.19 0.576 78 779 exclusion phecode
737 Curvature of spine Musculoskeletal 1.01 0.909 – 1.11 0.902 462 3890 exclusion phecode
737.1 Kyphosis (acquired) Musculoskeletal 1.06 0.865 – 1.31 0.56 110 1080 exclusion phecode
737.2 Lordosis (acquired) Musculoskeletal 0.994 0.541 – 1.83 0.984 12 152 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.978 0.876 – 1.09 0.701 386 3060 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.14 1.05 – 1.24 0.00311 631 5535 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.14 0.98 – 1.33 0.0883 198 2157 exclusion phecode
739 Contracture of joint Musculoskeletal 1.06 0.891 – 1.26 0.505 160 1370 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.05 1 – 1.1 0.049 2937 7929 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.989 0.923 – 1.06 0.754 1157 6673 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.984 0.915 – 1.06 0.668 1023 6187 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.11 0.914 – 1.34 0.297 122 1668 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.04 0.916 – 1.18 0.541 306 2887 exclusion phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 1.19 0.92 – 1.53 0.188 71 857 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.05 1 – 1.1 0.0452 2783 7867 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.01 0.961 – 1.07 0.635 1879 8544 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.929 0.698 – 1.24 0.612 54 599 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 0.968 0.859 – 1.09 0.595 323 2891 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 1.11 1.01 – 1.23 0.0291 496 4936 exclusion phecode
741.4 Joint effusions Musculoskeletal 0.994 0.907 – 1.09 0.891 540 5845 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.03 0.648 – 1.62 0.914 18 199 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 1.4 0.746 – 2.61 0.297 11 169 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.986 0.921 – 1.05 0.678 1043 8142 exclusion phecode
742.1 Loose body in joint Musculoskeletal 1.09 0.757 – 1.58 0.634 28 422 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.915 0.73 – 1.15 0.441 85 933 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.22 0.936 – 1.58 0.142 62 634 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.977 0.911 – 1.05 0.51 985 8034 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.04 0.99 – 1.09 0.118 2537 8248 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.07 0.992 – 1.15 0.0809 1230 3995 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.06 0.99 – 1.14 0.0932 1217 3952 exclusion phecode
743.12 Senile osteoporosis Musculoskeletal 0.958 0.834 – 1.1 0.543 292 1134 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1.11 0.885 – 1.39 0.372 109 601 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.05 0.931 – 1.19 0.405 326 2028 exclusion phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 1.08 0.885 – 1.31 0.464 131 862 exclusion phecode
743.22 Pathologic fracture of femur Musculoskeletal 1.42 1 – 2.02 0.049 43 267 exclusion phecode
743.4 Stress fracture Musculoskeletal 0.863 0.705 – 1.06 0.151 120 924 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.02 0.968 – 1.08 0.405 1853 7744 exclusion phecode
745 Pain in joint Musculoskeletal 0.959 0.921 – 0.998 0.0386 4517 6498 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.995 0.906 – 1.09 0.924 525 4965 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.03 0.924 – 1.15 0.598 389 3920 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.956 0.807 – 1.13 0.599 170 1512 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.1 0.905 – 1.33 0.342 128 1550 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.876 0.697 – 1.1 0.255 88 884 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.959 0.804 – 1.14 0.636 140 1163 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.822 0.553 – 1.22 0.332 29 272 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.887 0.761 – 1.03 0.127 206 1544 exclusion phecode
749.1 Cleft palate Congenital Anomalies 0.774 0.556 – 1.08 0.129 43 310 exclusion phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.874 0.628 – 1.22 0.426 46 303 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 1.22 1.07 – 1.4 0.00321 261 2050 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.05 0.841 – 1.32 0.654 88 858 exclusion phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.972 0.649 – 1.46 0.892 29 248 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.11 0.728 – 1.69 0.632 24 258 exclusion phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 1.09 0.775 – 1.52 0.629 39 269 exclusion phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 1.06 0.542 – 2.07 0.867 11 122 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.26 1.07 – 1.49 0.00605 176 1251 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.42 1.14 – 1.75 0.00144 110 720 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.11 0.838 – 1.46 0.474 69 509 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.03 0.94 – 1.14 0.493 518 4659 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.982 0.828 – 1.17 0.836 161 1548 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.08 0.883 – 1.32 0.453 116 1100 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.89 0.637 – 1.24 0.493 38 353 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.01 0.894 – 1.13 0.915 332 3026 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 1.05 0.911 – 1.21 0.505 227 2060 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.933 0.731 – 1.19 0.579 74 675 exclusion phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.31 0.981 – 1.74 0.0676 62 532 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.08 0.933 – 1.24 0.318 227 2647 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.11 0.951 – 1.31 0.182 177 2072 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.921 0.67 – 1.26 0.609 42 500 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.916 0.696 – 1.21 0.535 58 599 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.1 0.817 – 1.48 0.532 52 476 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.817 0.469 – 1.42 0.476 14 150 exclusion phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 0.885 0.518 – 1.51 0.655 14 144 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.04 0.907 – 1.19 0.57 247 2582 exclusion phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 0.902 0.6 – 1.36 0.619 27 305 exclusion phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 1.02 0.826 – 1.25 0.879 109 1222 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.04 0.886 – 1.23 0.62 175 1999 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.977 0.771 – 1.24 0.847 78 912 exclusion phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 1.15 0.708 – 1.86 0.578 18 180 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.08 0.852 – 1.37 0.521 84 961 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.06 0.777 – 1.45 0.71 50 565 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.09 0.974 – 1.22 0.132 354 3352 exclusion phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.737 0.453 – 1.2 0.22 21 172 exclusion phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 1.26 0.901 – 1.76 0.176 49 237 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.939 0.726 – 1.21 0.632 62 840 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.09 0.951 – 1.26 0.208 229 2290 exclusion phecode
757 Congenital anomalies of the integument Congenital Anomalies 0.838 0.671 – 1.05 0.121 103 926 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.17 0.874 – 1.55 0.296 58 491 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.18 0.832 – 1.67 0.356 38 363 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.909 0.767 – 1.08 0.271 160 1493 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.979 0.569 – 1.68 0.939 14 188 exclusion phecode
760 Back pain Symptoms 1.08 1.03 – 1.13 0.000432 3440 7569 exclusion phecode
761 Cervicalgia Symptoms 1.05 0.989 – 1.11 0.118 1576 9228 exclusion phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 1.02 0.938 – 1.11 0.645 662 7263 exclusion phecode
764 Sciatica Symptoms 1.07 0.982 – 1.17 0.121 611 7266 exclusion phecode
765 Cervical radiculitis Symptoms 1.06 0.946 – 1.18 0.328 371 3862 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.06 0.994 – 1.14 0.0724 1017 8661 exclusion phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.21 0.806 – 1.81 0.36 28 264 exclusion phecode
769 Nonallopathic lesions NEC Symptoms 0.99 0.87 – 1.13 0.884 292 2634 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.03 0.967 – 1.1 0.356 1254 8242 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.08 1.01 – 1.16 0.0308 1015 8355 exclusion phecode
771.1 Swelling of limb Symptoms 1.11 1.04 – 1.19 0.00252 1061 8316 exclusion phecode
771.2 Cramp of limb Symptoms 1.1 0.951 – 1.26 0.205 233 2375 exclusion phecode
772 Symptoms of the muscles Symptoms 0.933 0.847 – 1.03 0.155 507 4726 exclusion phecode
772.1 Muscular wasting and disuse atrophy Symptoms 1.03 0.848 – 1.25 0.767 123 1091 exclusion phecode
772.2 Spasm of muscle Symptoms 1 0.915 – 1.1 0.938 542 5508 exclusion phecode
772.3 Muscle weakness Symptoms 1.06 0.975 – 1.16 0.17 640 6137 exclusion phecode
772.4 Rhabdomyolysis Symptoms 1.45 1.02 – 2.07 0.041 38 338 exclusion phecode
772.6 Facial weakness Symptoms 0.854 0.687 – 1.06 0.156 96 1027 exclusion phecode
780 Hypothermia/Chills Symptoms 1.13 0.915 – 1.38 0.262 104 987 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1 0.915 – 1.1 0.977 574 5709 exclusion phecode
781.1 Loss of height Symptoms 1.23 0.84 – 1.8 0.288 35 214 exclusion phecode
781.2 Abnormal posture Symptoms 1.08 0.627 – 1.87 0.777 14 123 exclusion phecode
782.3 Edema Symptoms 1.18 1.1 – 1.26 4.93e-06 976 8470 exclusion phecode
782.6 Pallor and flushing Symptoms 0.904 0.787 – 1.04 0.155 245 2410 exclusion phecode
783 Fever of unknown origin Symptoms 1.13 1.06 – 1.19 1e-04 1350 9562 exclusion phecode
783.1 Postprocedural fever Symptoms 1.16 0.876 – 1.54 0.295 58 642 exclusion phecode
785 Abdominal pain Symptoms 1.04 1 – 1.09 0.0472 3950 7061 exclusion phecode
788 Syncope and collapse Symptoms 1.06 0.982 – 1.14 0.143 887 8223 exclusion phecode
789 Nausea and vomiting Symptoms 1.09 1.04 – 1.14 0.000293 2685 8302 exclusion phecode
789.1 Persistent vomiting Symptoms 1.28 1.1 – 1.49 0.00124 203 1910 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.07 0.975 – 1.18 0.147 499 4987 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.19 0.868 – 1.64 0.278 42 564 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.1 1.03 – 1.16 0.0024 1441 9098 exclusion phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.07 0.796 – 1.44 0.649 46 771 exclusion phecode
790.9 Abnormal arterial blood gases Symptoms 1.42 0.963 – 2.09 0.0766 27 339 exclusion phecode
791 Gangrene Symptoms 1.24 0.98 – 1.56 0.0738 77 589 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 1.04 0.967 – 1.13 0.265 885 4183 exclusion phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 1.08 0.967 – 1.21 0.17 370 2793 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.01 0.818 – 1.25 0.913 96 1118 exclusion phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 1.05 0.966 – 1.15 0.24 639 5303 exclusion phecode
795.8 Abnormal tumor markers Symptoms 0.892 0.785 – 1.01 0.0763 295 2567 exclusion phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 0.982 0.525 – 1.84 0.956 11 129 exclusion phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 1.03 0.768 – 1.38 0.845 59 490 exclusion phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.766 0.67 – 0.876 9.58e-05 314 1514 exclusion phecode
797 Shock Symptoms 1.18 0.965 – 1.43 0.108 129 1151 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.27 0.926 – 1.74 0.138 54 436 exclusion phecode
798 Malaise and fatigue Symptoms 1.04 0.997 – 1.09 0.069 2655 8349 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1.01 0.906 – 1.13 0.851 383 4177 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.1 1 – 1.2 0.0454 595 5364 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.22 1.02 – 1.47 0.0327 151 1086 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.09 0.927 – 1.27 0.31 192 1460 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.19 1.03 – 1.38 0.0163 221 2131 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.937 0.76 – 1.15 0.538 105 871 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.02 0.929 – 1.12 0.679 536 5414 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.06 0.922 – 1.21 0.434 249 2719 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.1 0.902 – 1.35 0.341 123 885 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.998 0.915 – 1.09 0.972 608 4860 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1.06 0.905 – 1.25 0.453 177 1770 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.968 0.862 – 1.09 0.585 360 2789 exclusion phecode
803.21 Colles' fracture Injuries & Poisonings 0.974 0.773 – 1.23 0.825 93 688 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.959 0.818 – 1.12 0.608 176 1228 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 1 0.908 – 1.1 0.977 491 3985 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.07 0.954 – 1.2 0.244 347 2856 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1 0.851 – 1.18 0.997 177 1371 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.992 0.92 – 1.07 0.837 829 6736 exclusion phecode
816 Cerebral laceration and contusion Injuries & Poisonings 1.7 0.96 – 3.03 0.0689 16 101 exclusion phecode
817 Concussion Injuries & Poisonings 1.03 0.898 – 1.17 0.696 258 2679 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.16 0.917 – 1.46 0.219 85 688 exclusion phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 1.45 0.903 – 2.31 0.125 24 189 exclusion phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.01 0.614 – 1.66 0.97 24 203 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.09 1 – 1.19 0.0466 607 5516 exclusion phecode
830 Dislocation Injuries & Poisonings 0.903 0.839 – 0.972 0.00651 868 8371 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.91 0.823 – 1 0.0617 465 5322 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.903 0.71 – 1.15 0.404 80 1028 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.923 0.875 – 0.974 0.00327 1782 9030 exclusion phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.967 0.765 – 1.22 0.776 82 1115 exclusion phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.97 0.847 – 1.11 0.661 253 3256 exclusion phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.899 0.83 – 0.973 0.00871 746 6296 exclusion phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.93 0.826 – 1.05 0.233 339 3848 exclusion phecode
842 Other sprains and strains Injuries & Poisonings 0.972 0.865 – 1.09 0.637 334 3490 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.14 1.03 – 1.26 0.0089 461 4470 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.22 1.12 – 1.32 3.25e-06 669 5863 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.39 1.13 – 1.71 0.00185 107 959 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.2 1.08 – 1.33 0.000706 412 4147 exclusion phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.06 0.788 – 1.42 0.713 54 619 exclusion phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.23 0.922 – 1.65 0.157 59 578 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.09 0.957 – 1.24 0.193 269 3092 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.15 1.04 – 1.26 0.00507 517 5130 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.21 1.11 – 1.33 3.85e-05 567 4779 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.16 0.81 – 1.66 0.418 40 366 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.11 1.03 – 1.18 0.004 997 8403 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.29 0.963 – 1.73 0.0873 55 444 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 0.85 0.61 – 1.19 0.338 41 324 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.05 0.941 – 1.17 0.379 392 3010 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.08 0.825 – 1.42 0.567 60 476 exclusion phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 1.23 0.972 – 1.55 0.0857 93 604 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 1.11 0.849 – 1.46 0.439 64 395 exclusion phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.1 0.774 – 1.57 0.584 38 391 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.09 1.01 – 1.18 0.0246 808 7420 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.02 0.846 – 1.24 0.809 128 1282 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.917 0.796 – 1.06 0.225 233 2284 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.53 1.22 – 1.93 0.000255 85 951 exclusion phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.32 0.966 – 1.81 0.0808 44 583 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.14 0.938 – 1.4 0.183 109 1075 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.45 1.03 – 2.05 0.0358 34 304 exclusion phecode
875 Non-healing surgical wound Injuries & Poisonings 1.15 0.958 – 1.39 0.132 127 1275 exclusion phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.12 0.942 – 1.32 0.204 148 1736 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.03 0.893 – 1.18 0.721 237 2291 exclusion phecode
910 Superficial injury, infected Injuries & Poisonings 0.955 0.613 – 1.49 0.84 22 268 exclusion phecode
911 Blister Injuries & Poisonings 1.09 0.804 – 1.47 0.589 50 571 exclusion phecode
912 Insect bite Injuries & Poisonings 1.06 0.867 – 1.29 0.585 112 1187 exclusion phecode
913 Toxic effect of venom Injuries & Poisonings 0.729 0.581 – 0.915 0.00638 85 744 exclusion phecode
916 Contusion Injuries & Poisonings 1.07 0.994 – 1.14 0.0726 987 8993 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 1.03 0.879 – 1.21 0.705 184 2047 exclusion phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.952 0.794 – 1.14 0.595 149 1629 exclusion phecode
938 Dermatitis due to solar radiation Dermatologic 0.906 0.85 – 0.966 0.00253 1328 6321 exclusion phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.908 0.67 – 1.23 0.531 48 508 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.9 0.843 – 0.96 0.00152 1269 6176 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1 0.945 – 1.06 0.929 1492 7699 exclusion phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 1.1 0.744 – 1.63 0.635 28 224 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.722 0.505 – 1.03 0.0737 37 380 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.44 1.1 – 1.89 0.00734 76 617 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.942 0.774 – 1.15 0.548 125 1147 exclusion phecode
947 Urticaria Dermatologic 0.986 0.869 – 1.12 0.822 287 2944 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.05 0.993 – 1.11 0.0828 1617 7675 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.15 0.94 – 1.41 0.175 107 1049 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.779 0.534 – 1.14 0.197 34 324 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.04 0.92 – 1.17 0.534 305 2721 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 0.758 0.528 – 1.09 0.133 38 329 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.37 0.93 – 2.01 0.111 34 249 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.21 1.1 – 1.33 5.17e-05 552 5167 exclusion phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 1.11 0.877 – 1.41 0.381 88 767 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.24 1.11 – 1.4 0.000264 342 3712 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.35 1.13 – 1.62 0.00121 138 1185 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.19 1.04 – 1.37 0.0145 233 2385 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.06 0.904 – 1.25 0.466 172 1659 exclusion phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.04 0.832 – 1.31 0.71 84 794 exclusion phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 1.69 0.88 – 3.24 0.115 11 118 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.847 – 1.29 0.674 99 974 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.12 1.03 – 1.22 0.00966 662 5444 exclusion phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.12 1.03 – 1.22 0.0103 644 5337 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.23 1.01 – 1.48 0.0351 129 1472 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.23 1.01 – 1.49 0.0423 120 1391 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.13 0.972 – 1.32 0.109 199 2115 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.31 1.16 – 1.48 1.76e-05 303 3397 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.999 0.672 – 1.49 0.998 27 247 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.53 1 – 2.34 0.0493 28 229 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.06 0.931 – 1.2 0.395 305 2905 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.58 1.22 – 2.05 0.000496 74 697 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.54 0.876 – 2.72 0.133 18 124 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.51 1.11 – 2.06 0.00922 51 576 exclusion phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 1.38 0.831 – 2.29 0.213 13 157 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.97 1.11 – 3.49 0.0204 16 198 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.44 0.911 – 2.29 0.118 21 234 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.863 0.514 – 1.45 0.576 14 199 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.777 0.444 – 1.36 0.377 15 160 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.15 1.03 – 1.29 0.0122 383 3849 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.15 1.07 – 1.24 0.000367 797 7171 exclusion phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 0.991 0.874 – 1.12 0.888 288 2809 exclusion phecode
985 Toxic effect of other metals Injuries & Poisonings 1.9 0.99 – 3.66 0.0537 17 92 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.17 0.831 – 1.66 0.363 34 302 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.11 1.03 – 1.19 0.00399 954 6503 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.26 1.14 – 1.39 9.85e-06 461 4485 exclusion phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.18 0.91 – 1.52 0.215 74 650 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.24 1.12 – 1.38 6.25e-05 429 4266 exclusion phecode
994.21 Septic shock Injuries & Poisonings 1.2 0.996 – 1.44 0.0554 138 1270 exclusion phecode
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