Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Body mass index Michigan Genomics Initiative Freeze 3 (MGI) PheWAS analysis

Body mass index — Michigan Genomics Initiative Freeze 3 (MGI) PRS PheWAS

PRS model
PRS ID exprsweb-bmi-23104-irnt-lassosum-mgi-freeze3-20211120Legacy LASSOSUMlassosumUK Biobank GWAS

Evaluation cohort: Michigan Genomics Initiative Freeze 3 (MGI).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: normal-range subset (18.5-24.9).

For this ExPRS, the exclusion sensitivity scan keeps only the study's normal-range subset for Body mass index (18.5-24.9) before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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712 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.05 1.01 – 1.09 0.0229 3004 29292 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.12 1.06 – 1.19 0.000113 1322 13162 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.12 1.05 – 1.2 0.000516 1046 10455 all phecode
008.6 Viral Enteritis Infectious Diseases 1.1 1.02 – 1.19 0.0135 770 7676 all phecode
010 Tuberculosis Infectious Diseases 1.13 0.99 – 1.3 0.0696 244 2425 all phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.958 0.76 – 1.21 0.717 86 855 all phecode
038 Septicemia Infectious Diseases 1.14 1.09 – 1.19 1.49e-09 2582 24779 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.15 1.05 – 1.26 0.00235 568 5629 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.21 1.05 – 1.38 0.00733 235 2350 all phecode
038.3 Bacteremia Infectious Diseases 1.13 1.06 – 1.2 0.000107 1210 12079 all phecode
041 Bacterial infection NOS Infectious Diseases 1.09 1.06 – 1.13 4.85e-10 5750 38799 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.2 1.14 – 1.27 1.3e-12 1707 16977 all phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.23 1.15 – 1.32 3.93e-09 920 9192 all phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.18 1.09 – 1.27 2.3e-05 783 7812 all phecode
041.2 Streptococcus infection Infectious Diseases 1.1 1.05 – 1.16 0.000232 1632 16287 all phecode
041.21 Rheumatic fever / chorea Infectious Diseases 0.993 0.871 – 1.13 0.915 257 2554 all phecode
041.4 E. coli Infectious Diseases 1.11 1.04 – 1.18 0.000965 1175 11680 all phecode
041.8 H. pylori Infectious Diseases 1.03 0.901 – 1.18 0.665 257 2521 all phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.24 1.11 – 1.38 9.07e-05 387 3864 all phecode
053 Herpes zoster Infectious Diseases 0.919 0.871 – 0.97 0.00213 1560 15184 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.873 0.757 – 1.01 0.0625 220 2169 all phecode
054 Herpes simplex Infectious Diseases 0.9 0.853 – 0.949 9.27e-05 1593 15600 all phecode
070 Viral hepatitis Infectious Diseases 1.03 0.961 – 1.11 0.371 829 8280 all phecode
070.1 Viral hepatitis A Infectious Diseases 0.986 0.79 – 1.23 0.898 87 860 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.01 0.875 – 1.17 0.881 215 2138 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.05 0.955 – 1.15 0.327 528 5280 all phecode
070.4 Chronic hepatitis Infectious Diseases 0.983 0.844 – 1.15 0.826 197 1964 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.01 0.953 – 1.08 0.651 1145 11381 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.12 0.943 – 1.32 0.2 145 1450 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.09 0.906 – 1.31 0.363 117 1163 all phecode
078 Viral warts & HPV Infectious Diseases 0.909 0.877 – 0.943 2.56e-07 3434 29624 all phecode
079 Viral infection Infectious Diseases 0.941 0.916 – 0.967 9.27e-06 6664 35342 all phecode
079.1 Varicella infection Infectious Diseases 0.878 0.848 – 0.909 2.8e-13 3793 31251 all phecode
079.2 Infectious mononucleosis Infectious Diseases 0.926 0.818 – 1.05 0.228 283 2723 all phecode
079.9 Viremia, NOS Infectious Diseases 1.06 0.988 – 1.14 0.102 838 8253 all phecode
080 Postoperative infection Infectious Diseases 1.18 1.13 – 1.23 1.65e-15 2619 26065 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.13 1.07 – 1.19 6.48e-06 1589 15884 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.996 0.931 – 1.07 0.907 965 9630 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.02 0.979 – 1.05 0.407 3544 30054 all phecode
110.1 Dermatophytosis Infectious Diseases 1.02 0.987 – 1.06 0.208 3241 27244 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.04 0.99 – 1.09 0.121 2044 16765 all phecode
110.12 Althete's foot Infectious Diseases 1.06 0.984 – 1.13 0.129 899 8043 all phecode
110.13 Dermatophytosis of the body Infectious Diseases 1.04 0.961 – 1.12 0.361 790 7827 all phecode
110.2 Dermatomycoses Infectious Diseases 0.967 0.871 – 1.07 0.525 398 3971 all phecode
112 Candidiasis Infectious Diseases 1.1 1.06 – 1.14 4.94e-08 3685 30495 all phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.29 1.19 – 1.4 6.13e-10 682 6732 all phecode
117 Mycoses Infectious Diseases 1.01 0.932 – 1.1 0.738 608 6069 all phecode
117.1 Histoplasmosis Infectious Diseases 1.06 0.843 – 1.33 0.624 81 801 all phecode
117.4 Aspergillosis Infectious Diseases 1.04 0.878 – 1.24 0.625 140 1387 all phecode
130 Spirochetal infection Infectious Diseases 0.896 0.765 – 1.05 0.169 168 1677 all phecode
130.1 Lyme disease Infectious Diseases 0.854 0.705 – 1.03 0.107 116 1160 all phecode
131 Protozoan infection Infectious Diseases 1.35 1.05 – 1.73 0.0174 61 610 all phecode
132 Infestation (lice, mites) Infectious Diseases 1.18 1.01 – 1.36 0.0315 195 1948 all phecode
134 Helminthiases Infectious Diseases 0.981 0.782 – 1.23 0.866 83 812 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.07 0.805 – 1.41 0.656 53 513 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.03 0.997 – 1.07 0.0705 3279 32486 all phecode
145 Cancer of mouth Neoplasms 1.05 0.994 – 1.11 0.0801 1481 14725 all phecode
145.1 Cancer of lip Neoplasms 1.21 0.958 – 1.53 0.109 76 750 all phecode
145.2 Cancer of tongue Neoplasms 1.01 0.93 – 1.1 0.814 645 6430 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.03 0.925 – 1.15 0.563 361 3597 all phecode
145.4 Cancer of the gums Neoplasms 1.1 0.929 – 1.3 0.271 166 1632 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.07 0.921 – 1.23 0.391 206 2048 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.05 0.987 – 1.11 0.128 1290 12873 all phecode
149.1 Cancer of oropharynx Neoplasms 1.08 0.966 – 1.21 0.176 350 3499 all phecode
149.2 Cancer of nasopharynx Neoplasms 1.12 0.911 – 1.38 0.279 100 1000 all phecode
149.3 Cancer of hypopharynx Neoplasms 0.96 0.754 – 1.22 0.741 82 819 all phecode
149.4 Cancer of larynx Neoplasms 1.19 1.07 – 1.32 0.00195 386 3857 all phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 1.06 0.97 – 1.16 0.193 552 5505 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.929 0.811 – 1.06 0.288 240 2398 all phecode
150 Cancer of esophagus Neoplasms 1.25 1.13 – 1.39 9.89e-06 433 4315 all phecode
151 Cancer of stomach Neoplasms 1.11 1.01 – 1.22 0.0357 498 4962 all phecode
153 Colorectal cancer Neoplasms 0.997 0.944 – 1.05 0.928 1458 14383 all phecode
153.2 Colon cancer Neoplasms 1 0.94 – 1.06 0.995 1160 11472 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.96 0.891 – 1.03 0.283 815 8093 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.06 0.965 – 1.16 0.227 511 5097 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.1 0.982 – 1.23 0.0983 344 3433 all phecode
157 Pancreatic cancer Neoplasms 0.967 0.88 – 1.06 0.491 503 5005 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.01 0.958 – 1.06 0.717 1623 15759 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.04 0.989 – 1.09 0.128 1818 17869 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.04 0.895 – 1.2 0.639 221 2206 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.987 0.835 – 1.17 0.88 158 1578 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.04 0.922 – 1.18 0.492 293 2920 all phecode
164 Cancer of intrathoracic organs Neoplasms 0.952 0.798 – 1.14 0.585 133 1324 all phecode
165 Cancer within the respiratory system Neoplasms 1.06 1 – 1.12 0.0516 1336 13340 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.05 0.987 – 1.13 0.116 1057 10552 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.984 0.937 – 1.03 0.531 1792 17850 all phecode
170.1 Bone cancer Neoplasms 0.973 0.903 – 1.05 0.483 773 7690 all phecode
170.2 Cancer of connective tissue Neoplasms 0.986 0.929 – 1.05 0.628 1266 12632 all phecode
172 Skin cancer Neoplasms 0.922 0.899 – 0.945 3.24e-10 8608 33186 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.901 0.874 – 0.929 3.25e-11 5330 30106 all phecode
172.11 Melanomas of skin Neoplasms 0.909 0.874 – 0.944 1.11e-06 3100 25064 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.92 0.894 – 0.945 2.84e-09 7095 30462 all phecode
172.21 Basal cell carcinoma Neoplasms 0.874 0.843 – 0.907 5.45e-13 3690 23868 all phecode
172.22 Squamous cell carcinoma Neoplasms 0.957 0.915 – 1 0.0523 2414 17683 all phecode
172.3 Carcinoma in situ of skin Neoplasms 0.881 0.832 – 0.931 9.02e-06 1482 12326 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.892 0.85 – 0.935 2.53e-06 1997 18755 all phecode
174 Breast cancer Neoplasms 0.89 0.855 – 0.927 1.39e-08 3186 15514 all phecode
174.1 Breast cancer [female] Neoplasms 0.89 0.854 – 0.927 2.48e-08 3036 14701 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.891 0.855 – 0.929 4.61e-08 2991 14639 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.796 0.694 – 0.914 0.0012 233 2307 all phecode
175 Acquired absence of breast Neoplasms 0.912 0.849 – 0.979 0.0105 919 8920 all phecode
180 Cervical cancer and dysplasia Neoplasms 1.02 0.967 – 1.08 0.427 1431 12185 all phecode
180.1 Cervical cancer Neoplasms 1.12 1.02 – 1.23 0.0182 500 4982 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.967 0.906 – 1.03 0.316 1048 9323 all phecode
182 Malignant neoplasm of uterus Neoplasms 1.13 1.04 – 1.21 0.00261 765 7613 all phecode
184 Cancer of other female genital organs Neoplasms 1.03 0.971 – 1.1 0.299 1191 11592 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.01 0.921 – 1.1 0.863 573 5719 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.984 0.888 – 1.09 0.761 432 4309 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.09 0.997 – 1.18 0.0576 608 6057 all phecode
185 Cancer of prostate Neoplasms 0.927 0.887 – 0.97 0.000901 2901 10342 all phecode
187 Cancer of other male genital organs Neoplasms 0.97 0.866 – 1.09 0.598 339 3384 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.14 0.934 – 1.38 0.2 115 1141 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.957 0.822 – 1.11 0.575 183 1830 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.793 0.603 – 1.04 0.0976 57 562 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.1 1.06 – 1.15 1.67e-06 2923 23541 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.12 1.06 – 1.19 5.3e-05 1450 14437 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.14 1.08 – 1.21 1.4e-05 1267 12655 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.01 0.881 – 1.17 0.837 237 2347 all phecode
189.2 Cancer of bladder Neoplasms 1.08 1.03 – 1.14 0.00288 1783 15224 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.08 1.03 – 1.14 0.00309 1657 14178 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.05 0.971 – 1.15 0.204 678 6586 all phecode
190 Cancer of eye Neoplasms 0.924 0.769 – 1.11 0.396 138 1374 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1 0.94 – 1.07 0.966 1078 10771 all phecode
191.1 Cancer of brain and nervous system Neoplasms 0.96 0.888 – 1.04 0.306 706 7052 all phecode
191.11 Cancer of brain Neoplasms 0.945 0.868 – 1.03 0.186 600 5996 all phecode
193 Thyroid cancer Neoplasms 1.03 0.963 – 1.1 0.383 945 9393 all phecode
194 Cancer of other endocrine glands Neoplasms 1.03 0.942 – 1.12 0.545 579 5759 all phecode
195 Cancer, suspected or other Neoplasms 0.996 0.975 – 1.02 0.697 16962 26401 all phecode
195.1 Malignant neoplasm, other Neoplasms 0.994 0.973 – 1.02 0.557 16670 26384 all phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1.02 0.955 – 1.08 0.599 1103 9766 all phecode
196 Radiotherapy Neoplasms 0.916 0.877 – 0.957 9.14e-05 2427 17006 all phecode
197 Chemotherapy Neoplasms 0.992 0.96 – 1.02 0.609 4952 23797 all phecode
198 Secondary malignant neoplasm Neoplasms 1.01 0.978 – 1.04 0.597 5801 23481 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.986 0.95 – 1.02 0.433 3677 21489 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.04 0.974 – 1.11 0.245 1072 10334 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1 0.931 – 1.07 0.995 866 8538 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 0.998 0.925 – 1.08 0.963 767 7558 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.968 0.891 – 1.05 0.45 640 6338 all phecode
198.6 Secondary malignancy of bone Neoplasms 0.983 0.915 – 1.06 0.644 866 8307 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.989 0.881 – 1.11 0.845 336 3253 all phecode
199 Neoplasm of uncertain behavior Neoplasms 0.993 0.963 – 1.02 0.634 5693 25767 all phecode
199.4 Neurofibromatosis Neoplasms 0.913 0.741 – 1.13 0.396 88 880 all phecode
200 Myeloproliferative disease Neoplasms 1.07 1 – 1.14 0.0517 1113 11098 all phecode
200.1 Polycythemia vera Neoplasms 1.15 1 – 1.32 0.0471 231 2310 all phecode
201 Hodgkin's disease Neoplasms 1.17 0.994 – 1.37 0.0599 172 1705 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.02 0.967 – 1.08 0.471 1559 15571 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1 0.945 – 1.06 0.962 1329 13268 all phecode
202.21 Nodular lymphoma Neoplasms 0.964 0.89 – 1.04 0.375 693 6923 all phecode
202.22 Reticulosarcoma Neoplasms 1.15 0.979 – 1.35 0.0895 170 1693 all phecode
202.24 Large cell lymphoma Neoplasms 1.11 0.942 – 1.31 0.21 160 1586 all phecode
204 Leukemia Neoplasms 1.05 0.967 – 1.14 0.248 689 6876 all phecode
204.1 Lymphoid leukemia Neoplasms 0.973 0.848 – 1.12 0.702 236 2354 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.892 0.702 – 1.13 0.353 74 734 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.957 0.813 – 1.13 0.595 173 1724 all phecode
204.2 Myeloid leukemia Neoplasms 1.11 0.975 – 1.27 0.112 265 2633 all phecode
204.21 Myeloid leukemia, acute Neoplasms 1.14 0.956 – 1.36 0.146 153 1516 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.927 0.7 – 1.23 0.598 61 610 all phecode
204.4 Multiple myeloma Neoplasms 1.14 0.987 – 1.32 0.0756 217 2162 all phecode
208 Benign neoplasm of colon Neoplasms 0.98 0.958 – 1 0.0863 10303 34953 all phecode
209 Neuroendocrine tumors Neoplasms 0.974 0.853 – 1.11 0.701 258 2580 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.977 0.93 – 1.02 0.335 1891 18839 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.09 1.06 – 1.12 9.63e-11 7329 36606 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.06 1.01 – 1.12 0.013 1843 18412 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.984 0.935 – 1.04 0.548 1677 15527 all phecode
214 Lipoma Neoplasms 0.982 0.929 – 1.04 0.527 1437 14132 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.944 0.879 – 1.01 0.119 883 8710 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.02 0.985 – 1.05 0.299 4528 39509 all phecode
216 Benign neoplasm of skin Neoplasms 0.916 0.896 – 0.936 2.29e-15 11528 34919 all phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 0.883 0.753 – 1.03 0.124 174 1701 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.813 0.773 – 0.856 1.8e-15 1786 17184 all phecode
217.1 Nevus, non-neoplastic Neoplasms 0.809 0.768 – 0.853 2.46e-15 1679 16116 all phecode
218 Benign neoplasm of uterus Neoplasms 1.01 0.971 – 1.04 0.773 4301 16661 all phecode
218.1 Uterine leiomyoma Neoplasms 0.982 0.934 – 1.03 0.47 1835 15733 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.01 0.969 – 1.05 0.729 3403 16447 all phecode
220 Benign neoplasm of ovary Neoplasms 1.04 0.973 – 1.12 0.228 893 8783 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.02 0.969 – 1.07 0.509 2042 14248 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.903 0.848 – 0.961 0.00133 1133 10663 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.03 0.98 – 1.09 0.23 1801 12657 all phecode
224 Benign neoplasm of eye Neoplasms 0.934 0.86 – 1.01 0.0986 691 6752 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.925 0.848 – 1.01 0.0837 595 5773 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.05 0.985 – 1.11 0.14 1209 12074 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.04 0.97 – 1.11 0.271 947 9454 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.04 0.919 – 1.18 0.536 289 2890 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.989 0.934 – 1.05 0.715 1329 13264 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.02 0.969 – 1.07 0.451 1690 16896 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.18 1.07 – 1.31 0.000791 467 4644 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.934 0.867 – 1.01 0.0734 795 7941 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.01 0.916 – 1.12 0.796 435 4350 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.852 0.813 – 0.892 8.63e-12 2149 20946 all phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.821 0.775 – 0.871 4.27e-11 1356 13336 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.982 0.958 – 1.01 0.166 7767 36615 all phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.973 0.946 – 1 0.0653 5743 34218 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.04 0.971 – 1.11 0.277 1031 9761 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.05 1.01 – 1.09 0.0221 2910 22227 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.04 0.996 – 1.09 0.0717 2265 19902 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.06 1 – 1.13 0.0374 1304 12479 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.05 0.989 – 1.11 0.115 1400 13425 all phecode
242.1 Graves' disease Endocrine/metabolic 1.07 0.979 – 1.18 0.13 515 5068 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.05 0.866 – 1.27 0.632 124 1224 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.06 0.934 – 1.19 0.383 292 2898 all phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 1.06 0.889 – 1.27 0.507 144 1432 all phecode
244 Hypothyroidism Endocrine/metabolic 1.07 1.04 – 1.1 4.9e-07 8099 32717 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.996 0.947 – 1.05 0.871 1762 17230 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.05 0.985 – 1.11 0.141 1261 11982 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.07 1.04 – 1.1 5.58e-07 7542 32208 all phecode
245 Thyroiditis Endocrine/metabolic 1.06 0.982 – 1.14 0.137 832 7882 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.06 0.978 – 1.15 0.157 686 6517 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.05 0.968 – 1.14 0.236 679 6449 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.05 1.02 – 1.08 0.00182 6129 30240 all phecode
246.2 Thyroid cyst Endocrine/metabolic 0.923 0.75 – 1.14 0.448 101 960 all phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1.02 0.946 – 1.09 0.677 886 8696 all phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.37 1.27 – 1.47 1.67e-17 1150 8340 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.28 1.25 – 1.31 2.4e-102 13947 31815 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.3 1.23 – 1.39 5e-18 2364 11758 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.02 0.856 – 1.22 0.824 262 960 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.14 1.01 – 1.28 0.0277 551 2686 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.24 1.11 – 1.38 0.000163 784 3018 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.22 1.08 – 1.37 0.00108 638 2675 all phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 1.06 0.871 – 1.29 0.552 155 850 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.39 1.36 – 1.43 2.01e-134 9843 29688 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.2 1.03 – 1.41 0.0226 282 1327 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.52 1.43 – 1.61 2.22e-46 1941 13510 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.4 1.31 – 1.5 1.05e-22 1643 9668 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.5 1.43 – 1.58 1.35e-54 2557 16502 all phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.48 1.36 – 1.61 1.34e-19 860 6143 all phecode
250.3 Insulin pump user Endocrine/metabolic 1.46 1.4 – 1.53 2.77e-61 3496 20809 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.17 1.13 – 1.2 6.14e-28 8385 30645 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.11 1.05 – 1.17 9.29e-05 1870 15861 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.17 1.14 – 1.21 1.01e-27 7553 30071 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.2 0.987 – 1.46 0.0672 136 1067 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.5 1.42 – 1.59 3.46e-43 2132 13390 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.19 1.12 – 1.26 1.85e-09 1691 10517 all phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.1 1.03 – 1.18 0.00569 991 8469 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.19 1.11 – 1.28 1.02e-06 1207 8570 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.08 1.03 – 1.12 0.00125 2282 22119 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.07 1.02 – 1.12 0.00722 2088 20335 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.04 0.942 – 1.14 0.471 508 5073 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1 0.935 – 1.08 0.894 859 8544 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.09 0.962 – 1.25 0.17 263 2621 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.16 0.921 – 1.46 0.207 83 826 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.01 0.877 – 1.16 0.926 226 2250 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.18 0.945 – 1.47 0.146 86 860 all phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 1.08 0.897 – 1.31 0.406 121 1209 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.945 0.774 – 1.15 0.579 108 1080 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.16 1.1 – 1.22 1.48e-07 1506 14869 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.06 0.949 – 1.18 0.31 373 3730 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.07 0.914 – 1.26 0.398 183 1830 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.04 0.871 – 1.25 0.653 135 1350 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.06 0.971 – 1.15 0.2 626 6239 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.06 0.971 – 1.15 0.198 596 5941 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.15 1.08 – 1.22 1.59e-05 1146 10513 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.31 1.21 – 1.42 9.38e-12 742 7128 all phecode
257 Testicular dysfunction Endocrine/metabolic 0.988 0.925 – 1.06 0.73 1015 9238 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.982 0.918 – 1.05 0.607 983 8933 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.2 0.97 – 1.48 0.093 91 910 all phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.992 0.81 – 1.21 0.937 109 1090 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.06 0.994 – 1.13 0.0756 1038 10259 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.03 0.987 – 1.07 0.182 2880 26812 all phecode
260.1 Cachexia Endocrine/metabolic 0.933 0.825 – 1.06 0.272 292 2911 all phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.05 0.993 – 1.1 0.0887 1691 16847 all phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.08 0.992 – 1.18 0.0739 614 6140 all phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.02 0.942 – 1.11 0.573 629 6236 all phecode
260.6 Anorexia Endocrine/metabolic 1.01 0.941 – 1.09 0.758 868 8591 all phecode
260.7 Polyphagia Endocrine/metabolic 1.09 0.844 – 1.42 0.496 65 643 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.13 1.1 – 1.16 3.48e-19 7718 35203 all phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1.24 0.946 – 1.61 0.121 69 690 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.25 1.16 – 1.34 2.55e-09 857 8405 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.13 1.1 – 1.16 1.86e-18 7255 35225 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.991 0.735 – 1.34 0.953 52 511 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.18 1.11 – 1.26 6.84e-08 1182 11676 all phecode
263 Other nutritional deficiency Endocrine/metabolic 1.1 1.04 – 1.15 0.000588 1651 15788 all phecode
264 Lack of normal physiological development Endocrine/metabolic 0.951 0.83 – 1.09 0.464 239 2301 all phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 0.955 0.791 – 1.15 0.633 122 1220 all phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 0.891 0.71 – 1.12 0.322 81 772 all phecode
269 Proteinuria Endocrine/metabolic 1.21 1.15 – 1.28 4.06e-13 1694 13981 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.07 1 – 1.15 0.041 967 9575 all phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.98 0.828 – 1.16 0.815 170 1697 all phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 1.01 0.839 – 1.22 0.906 134 1334 all phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 1.2 0.973 – 1.49 0.0872 96 954 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.06 0.98 – 1.15 0.143 737 7303 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.11 0.997 – 1.24 0.0564 384 3781 all phecode
270.33 Amyloidosis Endocrine/metabolic 0.936 0.733 – 1.19 0.595 71 695 all phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 0.857 0.66 – 1.11 0.245 69 690 all phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.04 0.922 – 1.18 0.518 299 2984 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.02 0.984 – 1.06 0.254 2907 28132 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.02 0.979 – 1.06 0.352 2827 27425 all phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.05 0.856 – 1.28 0.665 102 1007 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.12 1.09 – 1.14 1.59e-24 18881 26670 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.12 1.09 – 1.14 1.75e-24 18843 26654 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.08 1.04 – 1.11 4.99e-06 5928 21600 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.14 1.07 – 1.2 1.78e-05 1360 11837 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.15 1.1 – 1.19 8.75e-12 3538 18449 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.03 0.918 – 1.17 0.572 313 3011 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.19 1.14 – 1.24 1.16e-15 2524 22729 all phecode
274.1 Gout Endocrine/metabolic 1.2 1.15 – 1.25 4.92e-16 2409 21991 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.19 1.11 – 1.27 2.4e-07 1082 10576 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.07 0.917 – 1.25 0.383 195 1890 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.08 0.922 – 1.27 0.337 183 1772 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.07 1.04 – 1.11 1.16e-05 4357 37091 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.898 0.778 – 1.04 0.145 218 2180 all phecode
275.11 Hereditary hemochromatosis Hematopoietic 0.915 0.742 – 1.13 0.405 99 990 all phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 1.07 0.83 – 1.39 0.588 62 614 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.16 1.09 – 1.24 2.53e-06 1154 11504 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.07 1.03 – 1.11 0.00049 3369 31544 all phecode
275.51 Hypocalcemia Endocrine/metabolic 1.07 0.998 – 1.15 0.0558 898 8969 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.08 1.02 – 1.14 0.0115 1366 13634 all phecode
275.6 Hypercalcemia Endocrine/metabolic 1.04 0.987 – 1.1 0.134 1468 14183 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.12 1.09 – 1.15 1.38e-20 9238 37046 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.14 1.1 – 1.17 3.92e-19 6352 34366 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.2 1.1 – 1.31 8.07e-05 550 5434 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.1 1.05 – 1.14 1.79e-05 2514 23219 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.18 1.13 – 1.22 4.1e-16 2992 25216 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.11 1.06 – 1.16 4.64e-06 2148 20909 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.13 1.08 – 1.19 1.04e-07 2086 20332 all phecode
276.41 Acidosis Endocrine/metabolic 1.13 1.07 – 1.19 1.7e-06 1788 17572 all phecode
276.42 Alkalosis Endocrine/metabolic 1.15 1.04 – 1.26 0.00451 476 4741 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.1 1.06 – 1.13 1.63e-08 4574 34527 all phecode
276.6 Fluid overload Endocrine/metabolic 1.27 1.2 – 1.34 4.99e-16 1384 13211 all phecode
276.8 Polydipsia Endocrine/metabolic 0.867 0.723 – 1.04 0.123 124 1240 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.14 1.1 – 1.18 3.01e-14 4112 35070 all phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.4 1.26 – 1.55 3.87e-10 403 3991 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.96 0.888 – 1.04 0.31 720 7161 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.11 1.04 – 1.19 0.0032 936 9270 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.14 1.05 – 1.22 0.000946 773 7668 all phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.36 1.26 – 1.46 3.44e-17 916 8359 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.61 1.58 – 1.64 1.74e-456 19419 27331 all phecode
278.1 Obesity Endocrine/metabolic 1.71 1.68 – 1.75 3.14e-524 17129 27321 all phecode
278.11 Morbid obesity Endocrine/metabolic 2.03 1.98 – 2.09 1.95e-522 8280 27172 all phecode
278.3 Localized adiposity Endocrine/metabolic 1.85 1.64 – 2.09 3.74e-23 324 3228 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.41 1.34 – 1.48 1.62e-44 2104 17411 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.03 0.988 – 1.07 0.174 2934 28612 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1 0.944 – 1.07 0.895 1161 11571 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.956 0.852 – 1.07 0.441 330 3278 all phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 1.02 0.942 – 1.1 0.645 754 7516 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.01 0.975 – 1.04 0.711 4885 36552 all phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 0.993 0.911 – 1.08 0.869 601 5988 all phecode
280 Iron deficiency anemias Hematopoietic 1.13 1.09 – 1.16 1.81e-13 4626 30873 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.13 1.09 – 1.16 4.81e-13 4484 30649 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.1 1.04 – 1.15 0.000383 1771 17196 all phecode
281 Other deficiency anemia Hematopoietic 1.01 0.924 – 1.11 0.771 519 5120 all phecode
281.1 Megaloblastic anemia Hematopoietic 0.978 0.856 – 1.12 0.738 253 2497 all phecode
281.11 Pernicious anemia Hematopoietic 1.01 0.831 – 1.24 0.893 114 1108 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.955 0.819 – 1.11 0.56 187 1817 all phecode
281.9 Deficiency anemias Hematopoietic 1.02 0.899 – 1.15 0.78 285 2830 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.14 1.01 – 1.28 0.0305 323 3188 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.17 1.01 – 1.35 0.0405 216 2113 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.21 1.04 – 1.41 0.0125 192 1920 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.2 1.01 – 1.41 0.0368 155 1550 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.28 0.985 – 1.67 0.0642 64 633 all phecode
284 Aplastic anemia Hematopoietic 1.07 0.985 – 1.15 0.112 697 6943 all phecode
284.1 Pancytopenia Hematopoietic 1.08 0.994 – 1.18 0.0681 612 6100 all phecode
285 Other anemias Hematopoietic 1.1 1.08 – 1.12 2.63e-17 11794 33591 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.11 1.07 – 1.15 8.71e-08 3325 27709 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.15 1.1 – 1.21 3.49e-09 2055 19939 all phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.23 1.15 – 1.32 4.3e-09 932 9106 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.07 0.989 – 1.16 0.0916 690 6892 all phecode
286 Coagulation defects Hematopoietic 1.1 1.06 – 1.14 9.24e-08 3844 33384 all phecode
286.1 Congenital coagulation defects Hematopoietic 1.05 0.923 – 1.2 0.445 250 2466 all phecode
286.11 Von willebrand's disease Hematopoietic 1.17 0.941 – 1.45 0.161 83 822 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.995 0.828 – 1.19 0.954 126 1260 all phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.12 1.08 – 1.16 3.66e-09 3354 25918 all phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 0.968 0.779 – 1.2 0.768 97 962 all phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 1.18 1.04 – 1.35 0.0126 254 2529 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.15 0.962 – 1.37 0.126 132 1294 all phecode
286.6 Defibrination syndrome Hematopoietic 1.1 1.06 – 1.15 2.73e-06 2579 25377 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.1 1.06 – 1.14 1.1e-06 3014 29294 all phecode
286.8 Hypercoagulable state Hematopoietic 1.05 0.981 – 1.13 0.148 846 8437 all phecode
286.81 Primary hypercoagulable state Hematopoietic 1.05 0.975 – 1.13 0.194 813 8111 all phecode
286.9 Abnormal coagulation profile Hematopoietic 1.14 1.08 – 1.22 2e-05 1182 11487 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.06 1.03 – 1.1 0.000945 3288 28474 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.02 0.885 – 1.17 0.794 211 2094 all phecode
287.3 Thrombocytopenia Hematopoietic 1.06 1.02 – 1.1 0.00278 2938 26323 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.07 0.982 – 1.17 0.122 601 5994 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.06 0.972 – 1.16 0.184 569 5686 all phecode
287.4 Qualitative platelet defects Hematopoietic 1.17 0.96 – 1.41 0.121 112 1120 all phecode
288 Diseases of white blood cells Hematopoietic 1.06 1.03 – 1.09 0.000135 4886 36527 all phecode
288.1 Decreased white blood cell count Hematopoietic 0.994 0.944 – 1.05 0.83 1599 15951 all phecode
288.11 Neutropenia Hematopoietic 1 0.942 – 1.07 0.917 1106 11041 all phecode
288.2 Elevated white blood cell count Hematopoietic 1.07 1.04 – 1.11 2.93e-05 4082 35079 all phecode
288.3 Eosinophilia Hematopoietic 0.854 0.732 – 0.996 0.045 187 1866 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.03 0.983 – 1.09 0.189 1757 17434 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1 0.933 – 1.07 0.977 918 9087 all phecode
289.4 Lymphadenitis Hematopoietic 1.04 1.01 – 1.08 0.0236 3888 34715 all phecode
289.5 Diseases of spleen Hematopoietic 1.05 0.94 – 1.17 0.406 393 3913 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.1 0.966 – 1.25 0.148 255 2550 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.14 1.02 – 1.27 0.0182 385 3813 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.04 0.976 – 1.1 0.244 1318 11547 all phecode
290.1 Dementias Mental Disorders 0.985 0.899 – 1.08 0.753 541 4910 all phecode
290.11 Alzheimer's disease Mental Disorders 1.02 0.857 – 1.22 0.804 151 1389 all phecode
290.12 Dementia with cerebral degenerations Mental Disorders 1.06 0.844 – 1.34 0.609 88 846 all phecode
290.13 Senile dementia Mental Disorders 0.989 0.88 – 1.11 0.855 340 3078 all phecode
290.16 Vascular dementia Mental Disorders 1.04 0.825 – 1.32 0.729 81 777 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.04 0.964 – 1.13 0.293 750 7358 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.935 0.871 – 1 0.0639 886 8618 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.01 0.973 – 1.06 0.512 2550 24810 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.906 0.775 – 1.06 0.217 175 1750 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.965 0.877 – 1.06 0.463 484 4807 all phecode
291.8 Alteration of consciousness Mental Disorders 1.03 0.98 – 1.08 0.266 2036 19974 all phecode
292 Neurological disorders Mental Disorders 1.02 0.992 – 1.05 0.168 5733 38553 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1 0.955 – 1.05 0.97 2013 19867 all phecode
292.11 Aphasia Mental Disorders 1.01 0.928 – 1.09 0.85 664 6581 all phecode
292.12 Symbolic dysfunction Mental Disorders 1.05 0.909 – 1.22 0.485 200 1988 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.966 0.867 – 1.08 0.529 389 3731 all phecode
292.3 Memory loss Mental Disorders 0.954 0.909 – 1 0.0555 1922 18158 all phecode
292.4 Altered mental status Mental Disorders 1.08 1.03 – 1.13 0.000424 2454 22725 all phecode
292.5 Transient alteration of awareness Mental Disorders 1 0.91 – 1.11 0.926 430 4285 all phecode
292.6 Hallucinations Mental Disorders 1.12 0.966 – 1.29 0.135 217 2147 all phecode
293 Symptoms involving head and neck Mental Disorders 0.919 0.83 – 1.02 0.102 414 4127 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.02 0.989 – 1.05 0.203 4417 38609 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.06 0.983 – 1.13 0.138 885 8229 all phecode
295.1 Schizophrenia Mental Disorders 0.885 0.74 – 1.06 0.181 138 1339 all phecode
295.2 Paranoid disorders Mental Disorders 1.12 0.924 – 1.36 0.249 118 1079 all phecode
295.3 Psychosis Mental Disorders 1.08 0.998 – 1.17 0.0552 716 6694 all phecode
296 Mood disorders Mental Disorders 1.08 1.06 – 1.11 5.62e-13 15356 20858 all phecode
296.1 Bipolar Mental Disorders 1.13 1.06 – 1.2 7.89e-05 1301 11264 all phecode
296.2 Depression Mental Disorders 1.09 1.06 – 1.11 3.72e-13 14833 20856 all phecode
296.22 Major depressive disorder Mental Disorders 1.09 1.06 – 1.11 4.91e-13 13850 20853 all phecode
297 Suicidal ideation or attempt Mental Disorders 1.1 1.03 – 1.18 0.00464 985 9050 all phecode
297.1 Suicidal ideation Mental Disorders 1.09 1.01 – 1.18 0.0214 788 7310 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.05 0.929 – 1.19 0.424 285 2654 all phecode
300 Anxiety disorders Mental Disorders 1.05 1.03 – 1.08 2.88e-06 15419 20850 all phecode
300.1 Anxiety disorder Mental Disorders 1.06 1.03 – 1.08 1.33e-06 14517 20855 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1.03 1 – 1.07 0.0387 5546 20512 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.03 0.975 – 1.1 0.263 1360 11377 all phecode
300.13 Phobia Mental Disorders 1.06 0.994 – 1.14 0.0753 1051 9542 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.942 0.839 – 1.06 0.311 328 3018 all phecode
300.4 Dysthymic disorder Mental Disorders 1.05 1.01 – 1.1 0.024 2420 16552 all phecode
300.8 Acute reaction to stress Mental Disorders 1.06 0.964 – 1.17 0.229 504 4825 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.12 1.04 – 1.21 0.00279 843 7909 all phecode
301 Personality disorders Mental Disorders 1.12 1.02 – 1.24 0.0196 477 4539 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.04 0.914 – 1.19 0.523 254 2393 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.968 0.932 – 1.01 0.0907 3700 13808 all phecode
302.1 Decreased libido Mental Disorders 0.923 0.836 – 1.02 0.115 447 4331 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.926 0.9 – 0.954 2.29e-07 6808 20043 all phecode
303.1 Dissociative disorder Mental Disorders 1.27 1.07 – 1.5 0.00659 161 1573 all phecode
303.3 Psychogenic disorder Mental Disorders 0.915 0.889 – 0.943 4.91e-09 6487 19888 all phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.93 0.843 – 1.03 0.151 471 4623 all phecode
303.4 Somatoform disorder Mental Disorders 1.01 0.945 – 1.07 0.862 1177 11180 all phecode
304 Adjustment reaction Mental Disorders 1.02 0.982 – 1.05 0.331 3888 20475 all phecode
305.2 Eating disorder Mental Disorders 1.31 1.22 – 1.41 1.12e-13 901 8329 all phecode
306 Other mental disorder Mental Disorders 1.04 0.989 – 1.1 0.123 1815 14133 all phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.06 0.967 – 1.16 0.212 587 3527 all phecode
306.9 Tension headache Mental Disorders 1.03 0.954 – 1.12 0.43 753 7277 all phecode
312 Conduct disorders Mental Disorders 1.11 0.978 – 1.26 0.106 254 2501 all phecode
312.3 Impulse control disorder Mental Disorders 1.08 0.859 – 1.36 0.503 74 736 all phecode
313 Pervasive developmental disorders Mental Disorders 1.04 0.986 – 1.09 0.156 1571 14633 all phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1.03 0.975 – 1.09 0.285 1392 13190 all phecode
313.2 Tics and stuttering Mental Disorders 1.19 0.945 – 1.49 0.142 77 770 all phecode
313.3 Autism Mental Disorders 0.934 0.719 – 1.21 0.608 64 621 all phecode
315 Develomental delays and disorders Mental Disorders 1.09 1.01 – 1.18 0.0356 684 6788 all phecode
315.1 Learning disorder Mental Disorders 1.14 0.922 – 1.4 0.229 87 860 all phecode
315.2 Speech and language disorder Mental Disorders 0.954 0.836 – 1.09 0.488 254 2539 all phecode
316 Substance addiction and disorders Mental Disorders 1.12 1.09 – 1.16 3.86e-11 3682 32680 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.995 0.915 – 1.08 0.904 634 6331 all phecode
317 Alcohol-related disorders Mental Disorders 1.04 0.994 – 1.08 0.0912 2525 22920 all phecode
317.1 Alcoholism Mental Disorders 1.03 0.983 – 1.08 0.211 1986 19339 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.02 0.924 – 1.14 0.653 408 4080 all phecode
318 Tobacco use disorder Mental Disorders 1.19 1.16 – 1.22 1.15e-44 8622 34842 all phecode
320 Meningitis Neurological 1.04 0.93 – 1.16 0.511 382 3820 all phecode
323 Encephalitis Neurological 1.09 0.937 – 1.27 0.26 181 1809 all phecode
323.8 Encephalitis, non-infectious Neurological 1.08 0.918 – 1.28 0.347 153 1527 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.15 1.01 – 1.3 0.0284 288 2880 all phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 0.932 0.705 – 1.23 0.619 53 530 all phecode
327 Sleep disorders Neurological 1.18 1.16 – 1.21 2.25e-58 14941 31602 all phecode
327.1 Hypersomnia Neurological 1.11 1.05 – 1.16 2.78e-05 2061 19110 all phecode
327.3 Sleep apnea Neurological 1.27 1.24 – 1.3 1.53e-89 10909 31304 all phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1.05 0.952 – 1.15 0.356 492 4784 all phecode
327.32 Obstructive sleep apnea Neurological 1.27 1.24 – 1.3 1.37e-78 8744 30530 all phecode
327.4 Insomnia Neurological 1.06 1.03 – 1.1 3.8e-05 5524 30960 all phecode
327.41 Organic or persistent insomnia Neurological 1.01 0.951 – 1.07 0.763 1265 12120 all phecode
327.5 Parasomnia Neurological 1.16 1.07 – 1.27 0.000507 604 5913 all phecode
327.6 Circadian rhythm sleep disorder Neurological 1.06 0.936 – 1.21 0.347 274 2666 all phecode
327.7 Sleep related movement disorders Neurological 1.15 1.09 – 1.21 7.65e-08 1786 17323 all phecode
327.71 Restless legs syndrome Neurological 1.17 1.1 – 1.23 2.82e-08 1570 15360 all phecode
327.72 Sleep related leg cramps Neurological 1.03 0.817 – 1.29 0.823 83 822 all phecode
331 Other cerebral degenerations Neurological 0.923 0.854 – 0.999 0.0477 717 7024 all phecode
331.1 Hydrocephalus Neurological 0.935 0.828 – 1.06 0.279 284 2836 all phecode
331.9 Cerebral degeneration, unspecified Neurological 0.938 0.846 – 1.04 0.223 419 4026 all phecode
332 Parkinson's disease Neurological 0.881 0.794 – 0.976 0.0158 415 4128 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.04 1 – 1.09 0.03 2868 26583 all phecode
333.1 Essential tremor Neurological 0.955 0.883 – 1.03 0.249 725 7163 all phecode
333.2 Myoclonus Neurological 1.2 1.02 – 1.41 0.0255 159 1590 all phecode
333.4 Torsion dystonia Neurological 0.846 0.756 – 0.946 0.0035 352 3504 all phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 0.889 0.715 – 1.1 0.286 89 890 all phecode
334 Degenerative disease of the spinal cord Neurological 1.05 0.987 – 1.12 0.12 1058 10562 all phecode
334.1 Spinocerebellar disease Neurological 1.08 0.855 – 1.37 0.514 79 790 all phecode
334.2 Anterior horn cell disease Neurological 0.977 0.799 – 1.19 0.823 110 1080 all phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 0.912 0.711 – 1.17 0.47 71 693 all phecode
335 Multiple sclerosis Neurological 1.09 0.986 – 1.21 0.0892 396 3951 all phecode
337 Disorders of the autonomic nervous system Neurological 1.01 0.935 – 1.08 0.869 808 7413 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.08 0.971 – 1.21 0.155 370 3164 all phecode
338 Pain Neurological 1.07 1.05 – 1.09 7.75e-14 20346 26417 all phecode
338.1 Acute pain Neurological 1.06 1.04 – 1.08 4.9e-09 15582 26313 all phecode
338.2 Chronic pain Neurological 1.12 1.09 – 1.14 3.28e-21 10994 26368 all phecode
339 Other headache syndromes Neurological 1.04 1.02 – 1.07 0.00135 9242 34658 all phecode
340 Migraine Neurological 1.04 1.02 – 1.07 0.00206 6708 30587 all phecode
340.1 Migrain with aura Neurological 1.04 0.999 – 1.07 0.0589 3624 23684 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.17 0.979 – 1.4 0.0838 133 1330 all phecode
342 Hemiplegia Neurological 1.04 0.943 – 1.14 0.439 464 4607 all phecode
343 Infantile cerebral palsy Neurological 1.04 0.831 – 1.29 0.752 85 847 all phecode
344 Other paralytic syndromes Neurological 1.05 0.966 – 1.13 0.27 682 6808 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.04 0.994 – 1.08 0.0929 2553 25307 all phecode
345.1 Epilepsy Neurological 1.01 0.933 – 1.09 0.847 747 7465 all phecode
345.11 Generalized convulsive epilepsy Neurological 1.01 0.887 – 1.16 0.83 233 2330 all phecode
345.12 Partial epilepsy Neurological 1.02 0.93 – 1.11 0.712 534 5335 all phecode
345.3 Convulsions Neurological 1.04 0.998 – 1.09 0.0636 2396 23796 all phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.985 0.847 – 1.15 0.849 183 1824 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.01 0.954 – 1.07 0.767 1472 14587 all phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.865 0.719 – 1.04 0.128 120 1181 all phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 0.886 0.724 – 1.08 0.236 110 1100 all phecode
347 Cataplexy and narcolepsy Neurological 1.14 0.92 – 1.4 0.238 101 1010 all phecode
348 Other conditions of brain Neurological 1.06 1.01 – 1.12 0.0174 1793 17894 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.03 0.964 – 1.11 0.352 905 9034 all phecode
348.4 Cerebral cysts Neurological 0.946 0.823 – 1.09 0.436 229 2290 all phecode
348.7 Coma Neurological 0.966 0.843 – 1.11 0.62 229 2275 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.1 1.02 – 1.18 0.0101 853 8479 all phecode
348.9 Other conditions of brain, NOS Neurological 1 0.959 – 1.05 0.951 2341 23287 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.06 0.991 – 1.14 0.089 941 9385 all phecode
350 Abnormal movement Neurological 1.02 0.996 – 1.05 0.0918 6706 38762 all phecode
350.1 Abnormal involuntary movements Neurological 1.03 0.989 – 1.06 0.172 3273 30524 all phecode
350.2 Abnormality of gait Neurological 1.02 0.985 – 1.06 0.262 3920 30520 all phecode
350.3 Lack of coordination Neurological 0.959 0.9 – 1.02 0.205 1062 10554 all phecode
350.5 Abnormal reflex Neurological 1.03 0.887 – 1.19 0.714 200 1988 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.954 0.873 – 1.04 0.304 558 5576 all phecode
351 Other peripheral nerve disorders Neurological 1.09 1.06 – 1.12 1.19e-10 7401 34460 all phecode
352 Disorders of other cranial nerves Neurological 1.03 0.975 – 1.08 0.315 1714 17106 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.01 0.919 – 1.11 0.869 535 5344 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.06 0.984 – 1.14 0.127 783 7826 all phecode
353 Nerve root and plexus disorders Neurological 1.07 1.03 – 1.1 9.96e-05 4256 33369 all phecode
353.1 Nerve plexus lesions Neurological 1.06 0.95 – 1.18 0.307 390 3900 all phecode
353.2 Nerve root lesions Neurological 1.03 0.858 – 1.24 0.74 130 1287 all phecode
355 Complex regional/central pain syndrome Neurological 1.02 0.934 – 1.12 0.626 531 5295 all phecode
355.1 Chronic pain syndrome Neurological 1.15 1.07 – 1.24 0.000198 843 8386 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.05 1.01 – 1.1 0.028 2335 20731 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.08 1.04 – 1.12 2.86e-05 3472 29956 all phecode
358 Myoneural disorders Neurological 1.1 1.04 – 1.17 0.00218 1147 11391 all phecode
358.1 Myasthenia gravis Neurological 0.865 0.707 – 1.06 0.16 109 1082 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.937 0.879 – 0.998 0.0423 1134 11274 all phecode
359.1 Muscular dystrophies Neurological 0.897 0.678 – 1.19 0.447 64 632 all phecode
359.2 Myopathy Neurological 0.94 0.882 – 1 0.0616 1092 10843 all phecode
360 Disorders of the globe Sense Organs 0.877 0.728 – 1.06 0.166 131 1276 all phecode
360.2 Progressive myopia Sense Organs 0.805 0.619 – 1.05 0.103 65 640 all phecode
361 Retinal detachments and defects Sense Organs 0.921 0.852 – 0.997 0.0415 733 7131 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.863 0.763 – 0.976 0.0186 302 2962 all phecode
362 Other retinal disorders Sense Organs 0.97 0.935 – 1.01 0.114 3569 22997 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.952 0.908 – 0.998 0.0422 2172 15483 all phecode
362.21 Macular degeneration, dry Sense Organs 0.874 0.784 – 0.975 0.0159 419 3438 all phecode
362.22 Macular degeneration, wet Sense Organs 0.926 0.774 – 1.11 0.402 148 1184 all phecode
362.23 Cystoid macular degeneration of retina Sense Organs 0.898 0.807 – 0.998 0.0452 408 3839 all phecode
362.26 Macular puckering of retina Sense Organs 0.916 0.855 – 0.981 0.0118 976 8610 all phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.897 0.814 – 0.989 0.0289 488 4558 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.957 0.91 – 1.01 0.087 1883 13955 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.02 0.956 – 1.1 0.51 976 8527 all phecode
362.31 Separation of retinal layers Sense Organs 0.932 0.84 – 1.03 0.179 413 4056 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.969 0.892 – 1.05 0.465 662 5933 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.915 0.822 – 1.02 0.102 392 3787 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.962 0.834 – 1.11 0.597 215 2103 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.05 0.918 – 1.2 0.465 241 2368 all phecode
362.9 Retinal edema Sense Organs 1.11 0.989 – 1.25 0.0769 324 2936 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.923 0.839 – 1.02 0.102 492 4746 all phecode
363.3 Chorioretinal scars Sense Organs 0.858 0.766 – 0.962 0.00844 332 3184 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.944 0.886 – 1.01 0.0755 1132 10772 all phecode
364.1 Corneal opacity Sense Organs 0.955 0.86 – 1.06 0.388 394 3846 all phecode
364.2 Corneal edema Sense Organs 1.08 0.897 – 1.3 0.414 123 1208 all phecode
364.4 Corneal degenerations Sense Organs 0.946 0.852 – 1.05 0.297 402 3962 all phecode
364.41 Keratoconus Sense Organs 0.825 0.646 – 1.05 0.124 75 739 all phecode
364.5 Corneal dystrophy Sense Organs 0.941 0.854 – 1.04 0.22 502 4682 all phecode
364.51 Fuchs' dystrophy Sense Organs 0.892 0.78 – 1.02 0.0941 266 2521 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.895 0.716 – 1.12 0.327 91 885 all phecode
365 Glaucoma Sense Organs 0.941 0.902 – 0.981 0.00427 2672 21326 all phecode
365.1 Open-angle glaucoma Sense Organs 0.89 0.822 – 0.965 0.00459 705 6491 all phecode
365.11 Primary open angle glaucoma Sense Organs 0.857 0.77 – 0.953 0.00443 403 3681 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.925 0.807 – 1.06 0.266 251 2370 all phecode
366 Cataract Sense Organs 0.969 0.944 – 0.995 0.0217 8611 28043 all phecode
366.1 Nonsenile Cataract Sense Organs 0.865 0.746 – 1 0.055 207 1979 all phecode
366.2 Senile cataract Sense Organs 0.953 0.923 – 0.984 0.00304 5480 24980 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.959 0.936 – 0.982 0.000647 8967 37779 all phecode
367.1 Myopia Sense Organs 0.943 0.914 – 0.972 0.000184 5014 34677 all phecode
367.2 Astigmatism Sense Organs 0.931 0.9 – 0.963 2.91e-05 4161 32463 all phecode
367.8 Hypermetropia Sense Organs 0.929 0.886 – 0.973 0.00205 2039 18599 all phecode
367.9 Blindness and low vision Sense Organs 1.04 0.976 – 1.1 0.253 1277 12356 all phecode
368 Visual disturbances Sense Organs 0.992 0.964 – 1.02 0.598 5715 39599 all phecode
368.1 Amblyopia Sense Organs 1.02 0.941 – 1.11 0.592 651 6479 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.983 0.922 – 1.05 0.605 1087 10786 all phecode
368.3 Anisometropia Sense Organs 0.874 0.756 – 1.01 0.0662 219 2168 all phecode
368.4 Visual field defects Sense Organs 0.999 0.939 – 1.06 0.987 1132 11173 all phecode
368.9 Subjective visual disturbances Sense Organs 1.02 0.96 – 1.09 0.475 1070 10620 all phecode
368.91 Psychophysical visual disturbances Sense Organs 1.21 0.994 – 1.46 0.0574 120 1171 all phecode
369 Infection of the eye Sense Organs 0.947 0.912 – 0.983 0.00432 3185 28240 all phecode
369.2 Eye infection, viral Sense Organs 0.938 0.853 – 1.03 0.191 502 4954 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.946 0.908 – 0.985 0.00752 2716 24970 all phecode
370 Keratitis Sense Organs 0.929 0.878 – 0.984 0.0118 1365 13169 all phecode
370.1 Corneal ulcer Sense Organs 0.927 0.808 – 1.06 0.279 223 2194 all phecode
370.2 Superficial keratitis Sense Organs 0.887 0.811 – 0.97 0.00836 546 5393 all phecode
370.3 Keratoconjunctivitis Sense Organs 1 0.924 – 1.09 0.934 649 6263 all phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.944 0.803 – 1.11 0.486 179 1677 all phecode
371 Inflammation of the eye Sense Organs 0.942 0.912 – 0.973 0.000351 4414 32310 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.976 0.892 – 1.07 0.598 541 5278 all phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.954 0.889 – 1.02 0.191 906 8939 all phecode
371.21 Allergic conjunctivitis Sense Organs 0.94 0.871 – 1.02 0.114 756 7515 all phecode
371.3 Inflammation of eyelids Sense Organs 0.932 0.898 – 0.967 0.000175 3398 26983 all phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 0.862 0.716 – 1.04 0.118 133 1291 all phecode
372 Disorders of conjunctiva Sense Organs 0.944 0.886 – 1 0.071 1118 10728 all phecode
374 Other disorders of eyelids Sense Organs 0.941 0.905 – 0.98 0.00292 2940 24188 all phecode
374.1 Ectropion or entropion Sense Organs 0.891 0.805 – 0.988 0.028 431 4084 all phecode
374.2 Lagophthalmos Sense Organs 1.06 0.926 – 1.22 0.387 235 2335 all phecode
374.3 Ptosis of eyelid Sense Organs 0.955 0.896 – 1.02 0.161 1102 10734 all phecode
374.6 Dermatochalasis Sense Organs 0.987 0.923 – 1.05 0.692 1040 9720 all phecode
375 Disorders of lacrimal system Sense Organs 0.955 0.921 – 0.99 0.0128 3694 26045 all phecode
375.1 Dry eyes Sense Organs 0.957 0.924 – 0.991 0.014 4040 26751 all phecode
375.2 Epiphora Sense Organs 0.928 0.838 – 1.03 0.149 442 4354 all phecode
376 Disorders of the orbit Sense Organs 1.05 0.938 – 1.17 0.409 352 3508 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.02 0.956 – 1.1 0.497 913 9021 all phecode
377.1 Optic atrophy Sense Organs 0.949 0.836 – 1.08 0.416 283 2793 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.04 0.95 – 1.13 0.426 585 5775 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.964 0.908 – 1.02 0.225 1275 12460 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.966 0.898 – 1.04 0.361 828 8130 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.994 0.848 – 1.16 0.938 170 1686 all phecode
378.5 Paralytic strabismus Sense Organs 0.889 0.794 – 0.995 0.04 349 3437 all phecode
379 Other disorders of eye Sense Organs 0.936 0.907 – 0.966 4.2e-05 5046 29999 all phecode
379.1 Scleritis and episcleritis Sense Organs 0.854 0.729 – 1 0.0514 176 1743 all phecode
379.2 Disorders of vitreous body Sense Organs 0.922 0.888 – 0.956 1.61e-05 3634 23186 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.818 0.684 – 0.978 0.0278 135 1258 all phecode
379.4 Anomalies of pupillary function Sense Organs 0.877 0.775 – 0.994 0.0395 287 2833 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.04 0.923 – 1.17 0.527 304 2948 all phecode
379.51 Pigmentary iris degeneration Sense Organs 0.957 0.749 – 1.22 0.721 77 731 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.979 0.92 – 1.04 0.52 1129 11130 all phecode
380 Disorders of external ear Sense Organs 0.89 0.851 – 0.931 3.88e-07 2242 20393 all phecode
380.1 Otitis externa Sense Organs 0.981 0.928 – 1.04 0.482 1469 14580 all phecode
380.4 Impacted cerumen Sense Organs 0.884 0.848 – 0.922 6.11e-09 2648 23557 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1 0.968 – 1.03 0.998 4255 36417 all phecode
381.1 Otitis media Sense Organs 1.05 1.01 – 1.09 0.019 3079 29813 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.05 1.01 – 1.1 0.0158 2610 25602 all phecode
381.2 Eustachian tube disorders Sense Organs 0.918 0.874 – 0.965 0.000738 1816 17827 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.11 0.935 – 1.31 0.237 153 1530 all phecode
381.9 Otorrhea Sense Organs 1.05 0.947 – 1.17 0.341 372 3713 all phecode
382 Otalgia Sense Organs 1.03 0.98 – 1.08 0.252 1884 18673 all phecode
383 Otosclerosis Sense Organs 0.933 0.772 – 1.13 0.473 124 1240 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.02 0.931 – 1.12 0.671 516 5156 all phecode
384.1 Myringitis Sense Organs 0.904 0.675 – 1.21 0.498 51 502 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.03 0.926 – 1.14 0.615 403 4029 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.01 0.917 – 1.12 0.802 432 4320 all phecode
385.3 Cholesteatoma Sense Organs 1.03 0.906 – 1.16 0.687 277 2770 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.02 0.847 – 1.23 0.823 118 1180 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.989 0.942 – 1.04 0.674 1882 18186 all phecode
386.1 Meniere's disease Sense Organs 0.969 0.86 – 1.09 0.598 319 3156 all phecode
386.2 Peripheral or central vertigo Sense Organs 0.993 0.942 – 1.05 0.811 1586 15423 all phecode
386.21 Central origin vertigo Sense Organs 1 0.942 – 1.06 0.958 1208 11844 all phecode
386.3 Labyrinthitis Sense Organs 0.998 0.944 – 1.05 0.94 1482 14530 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.01 0.988 – 1.04 0.275 6933 38286 all phecode
388 Other disorders of ear Sense Organs 0.978 0.914 – 1.05 0.519 960 9501 all phecode
389 Hearing loss Sense Organs 0.978 0.954 – 1 0.0801 8182 38069 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.926 0.895 – 0.958 9.25e-06 4107 29258 all phecode
389.2 Conductive hearing loss Sense Organs 0.961 0.896 – 1.03 0.254 905 9042 all phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.957 0.822 – 1.11 0.565 192 1808 all phecode
389.4 Tinnitus Sense Organs 0.909 0.87 – 0.95 2.24e-05 2291 22130 all phecode
389.5 Disorders of acoustic nerve Sense Organs 1.02 0.844 – 1.23 0.851 124 1229 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.05 0.995 – 1.11 0.0739 1458 13732 all phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 1.05 0.938 – 1.18 0.396 350 3415 all phecode
394.2 Mitral valve disease Circulatory System 1.04 0.946 – 1.15 0.392 462 4560 all phecode
394.3 Aortic valve disease Circulatory System 1.01 0.863 – 1.19 0.877 176 1691 all phecode
394.4 Acute rheumatic heart disease Circulatory System 1.11 0.836 – 1.46 0.483 55 546 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.06 0.972 – 1.16 0.186 587 5739 all phecode
395 Heart valve disorders Circulatory System 1.02 0.981 – 1.05 0.374 3976 28748 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.952 0.909 – 0.996 0.0324 2175 20441 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.09 1.04 – 1.15 0.000255 2060 17194 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.05 0.956 – 1.16 0.3 493 4864 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.988 0.806 – 1.21 0.908 108 1080 all phecode
395.6 Heart valve replaced Circulatory System 1.11 1.05 – 1.19 0.000709 1177 10833 all phecode
396 Abnormal heart sounds Circulatory System 0.992 0.961 – 1.02 0.598 4718 34395 all phecode
401 Hypertension Circulatory System 1.31 1.28 – 1.34 2.82e-134 23317 23367 all phecode
401.1 Essential hypertension Circulatory System 1.31 1.29 – 1.34 1.06e-135 23158 23364 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.45 1.39 – 1.51 4.36e-67 3503 14616 all phecode
401.21 Hypertensive heart disease Circulatory System 1.39 1.29 – 1.5 1.77e-18 893 6607 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.43 1.36 – 1.5 4.47e-51 2584 13072 all phecode
401.3 Other hypertensive complications Circulatory System 1.31 1.25 – 1.37 2.27e-33 2679 15833 all phecode
411 Ischemic Heart Disease Circulatory System 1.18 1.15 – 1.21 4.49e-36 8807 30299 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.18 1.1 – 1.27 2.39e-06 937 8574 all phecode
411.2 Myocardial infarction Circulatory System 1.24 1.2 – 1.29 2.89e-30 3594 21716 all phecode
411.3 Angina pectoris Circulatory System 1.19 1.14 – 1.24 3.21e-15 2485 18304 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.19 1.15 – 1.22 6.27e-33 7555 27492 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.19 0.996 – 1.41 0.055 156 1529 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.21 1.17 – 1.24 1.32e-34 6331 25741 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.2 1.08 – 1.33 0.000387 442 4211 all phecode
414 Other forms of chronic heart disease Circulatory System 1.12 1.08 – 1.17 1.03e-08 3101 22616 all phecode
414.2 ASCVD Circulatory System 1.12 1.03 – 1.21 0.00649 718 6816 all phecode
415 Pulmonary heart disease Circulatory System 1.16 1.12 – 1.2 5.53e-15 3366 30208 all phecode
415.1 Acute pulmonary heart disease Circulatory System 1.13 1.08 – 1.19 3.96e-07 1912 19014 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.13 1.08 – 1.19 3.1e-07 1906 18953 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.18 1.12 – 1.24 7.99e-11 1808 17605 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.14 1.05 – 1.23 0.00126 706 7032 all phecode
416 Cardiomegaly Circulatory System 1.1 1.04 – 1.17 0.00149 1254 12372 all phecode
418 Nonspecific chest pain Circulatory System 1.05 1.03 – 1.08 1.92e-06 12650 33952 all phecode
418.1 Precordial pain Circulatory System 1.04 0.987 – 1.1 0.135 1471 13782 all phecode
420 Carditis Circulatory System 1.08 1.03 – 1.14 0.00356 1588 15680 all phecode
420.1 Myocarditis Circulatory System 1.16 0.932 – 1.44 0.184 97 958 all phecode
420.2 Pericarditis Circulatory System 1.06 0.984 – 1.14 0.123 842 8402 all phecode
420.21 Acute pericarditis Circulatory System 1.18 1.01 – 1.37 0.0409 177 1764 all phecode
420.22 Chronic pericarditis Circulatory System 1.29 1.05 – 1.57 0.0133 117 1153 all phecode
420.3 Endocarditis Circulatory System 1.13 1.05 – 1.22 0.00202 764 7535 all phecode
425 Cardiomyopathy Circulatory System 1.13 1.08 – 1.19 1.19e-07 2078 19881 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.14 1.09 – 1.2 4.09e-08 1989 19025 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.06 0.918 – 1.23 0.424 208 2050 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.12 0.963 – 1.29 0.145 201 1992 all phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.02 0.909 – 1.15 0.706 317 3170 all phecode
425.8 Other cardiomyopathy Circulatory System 1.01 0.808 – 1.27 0.909 95 931 all phecode
426 Cardiac conduction disorders Circulatory System 1.08 1.05 – 1.11 1.76e-10 12327 25440 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.12 1.06 – 1.17 2.73e-05 1903 11501 all phecode
426.21 First degree AV block Circulatory System 1.09 1.03 – 1.16 0.00392 1313 8899 all phecode
426.22 Mobitz II AV block Circulatory System 0.944 0.718 – 1.24 0.682 64 553 all phecode
426.23 Second degree AV block Circulatory System 0.969 0.837 – 1.12 0.671 216 1925 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.07 0.966 – 1.18 0.2 461 3823 all phecode
426.25 Other heart block Circulatory System 1.02 0.877 – 1.18 0.823 203 1803 all phecode
426.3 Bundle branch block Circulatory System 1.07 1.02 – 1.12 0.0054 2306 13999 all phecode
426.31 Right bundle branch block Circulatory System 1.07 1.01 – 1.13 0.0312 1423 10758 all phecode
426.32 Left bundle branch block Circulatory System 1.09 1.02 – 1.17 0.0134 969 8110 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1 0.801 – 1.25 0.987 82 820 all phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.08 1.05 – 1.11 1.71e-09 10577 25186 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.07 0.984 – 1.16 0.115 679 6650 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.1 1.04 – 1.16 0.000473 1754 11536 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.11 1.04 – 1.19 0.00106 1171 8184 all phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.11 1.03 – 1.19 0.00602 846 7320 all phecode
427 Cardiac dysrhythmias Circulatory System 1.05 1.03 – 1.07 7.64e-06 17397 25735 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.04 0.998 – 1.09 0.0638 2474 18178 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.03 0.981 – 1.09 0.21 1595 14293 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.07 1.01 – 1.14 0.0285 1181 9915 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.09 1.05 – 1.13 4.49e-07 5313 18688 all phecode
427.21 Atrial fibrillation Circulatory System 1.09 1.05 – 1.13 8.81e-07 5188 18409 all phecode
427.22 Atrial flutter Circulatory System 1.06 1 – 1.11 0.044 1693 11042 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.05 1.02 – 1.08 0.000259 8688 25552 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.05 0.955 – 1.15 0.332 536 5233 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.887 0.768 – 1.02 0.104 216 2118 all phecode
427.42 Cardiac arrest Circulatory System 1.13 1.02 – 1.26 0.0188 410 4034 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.04 1.01 – 1.07 0.0072 6905 25457 all phecode
427.6 Premature beats Circulatory System 1.02 0.978 – 1.07 0.327 2359 16248 all phecode
427.61 Supraventricular premature beats Circulatory System 1.06 0.974 – 1.15 0.185 670 6287 all phecode
427.7 Tachycardia NOS Circulatory System 1.09 1.05 – 1.12 2.05e-07 5124 25531 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.06 0.991 – 1.14 0.0854 912 7501 all phecode
427.9 Palpitations Circulatory System 0.976 0.944 – 1.01 0.144 4430 24505 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.23 1.18 – 1.27 6.12e-31 4300 23663 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.24 1.19 – 1.28 9.35e-30 3756 22446 all phecode
428.2 Heart failure NOS Circulatory System 1.26 1.22 – 1.31 4.55e-35 3701 21722 all phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.22 1.16 – 1.29 1.35e-14 1765 14476 all phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.31 1.24 – 1.38 2.01e-22 1648 13395 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.06 1.04 – 1.09 1.43e-08 12635 32504 all phecode
429.1 Heart transplant/surgery Circulatory System 1.07 1.01 – 1.14 0.0201 1219 11696 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.1 1.07 – 1.13 3.03e-11 6322 29232 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.05 1.03 – 1.08 5.91e-05 9650 32421 all phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.08 1 – 1.17 0.0471 723 7072 all phecode
430 Intracranial hemorrhage Circulatory System 0.924 0.857 – 0.996 0.0386 789 7842 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.929 0.815 – 1.06 0.275 261 2610 all phecode
430.2 Intracerebral hemorrhage Circulatory System 0.957 0.858 – 1.07 0.434 368 3671 all phecode
430.3 Subdural hemorrhage Circulatory System 0.825 0.727 – 0.937 0.00304 272 2680 all phecode
433 Cerebrovascular disease Circulatory System 1.09 1.06 – 1.13 8.51e-09 5463 32242 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.11 1.05 – 1.16 4.91e-05 1978 16212 all phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.2 1.05 – 1.38 0.00761 260 2517 all phecode
433.12 Cerebral atherosclerosis Circulatory System 0.991 0.785 – 1.25 0.941 80 789 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.1 1.05 – 1.15 1.13e-05 2437 21732 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.1 1.05 – 1.15 1.69e-05 2357 21103 all phecode
433.3 Cerebral ischemia Circulatory System 1.06 1.02 – 1.1 0.00697 2780 22868 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.08 1.03 – 1.13 0.000708 2409 20762 all phecode
433.5 Cerebral aneurysm Circulatory System 1.08 0.979 – 1.19 0.125 474 4724 all phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.13 1.03 – 1.25 0.0138 464 4518 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.12 1.03 – 1.21 0.00742 695 6822 all phecode
440 Atherosclerosis Circulatory System 1.16 1.11 – 1.22 1.04e-11 2477 19724 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.12 0.977 – 1.29 0.103 231 2291 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.15 1.09 – 1.22 4.72e-07 1516 13532 all phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.28 1.13 – 1.46 0.000131 274 2669 all phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.14 1.07 – 1.22 0.000104 1040 9647 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.19 1.11 – 1.28 2.3e-06 846 8124 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.09 0.991 – 1.19 0.0753 515 5115 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.04 0.911 – 1.19 0.551 240 2387 all phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.12 0.948 – 1.33 0.182 154 1536 all phecode
442 Other aneurysm Circulatory System 1.12 1.07 – 1.16 1.26e-07 2779 21466 all phecode
442.1 Aortic aneurysm Circulatory System 1.12 1.07 – 1.17 3.18e-06 2054 16492 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.12 1.06 – 1.2 0.000269 1189 10558 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.12 0.962 – 1.3 0.144 202 2002 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.05 0.895 – 1.22 0.565 179 1765 all phecode
442.4 Arterial dissection Circulatory System 0.95 0.813 – 1.11 0.516 184 1840 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.14 1.03 – 1.27 0.013 399 3978 all phecode
443 Peripheral vascular disease Circulatory System 1.1 1.05 – 1.14 3.29e-06 3086 24814 all phecode
443.1 Raynaud's syndrome Circulatory System 0.864 0.8 – 0.933 0.000203 742 7390 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.32 1.15 – 1.53 0.000125 220 2087 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.1 1.06 – 1.15 7.49e-06 2557 21985 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.16 1.11 – 1.22 2.52e-11 2341 18862 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.11 1.04 – 1.2 0.00374 848 8423 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1 0.89 – 1.13 0.954 313 3099 all phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 1.01 0.854 – 1.2 0.897 155 1548 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.02 0.928 – 1.13 0.631 460 4559 all phecode
446.4 Wegener's granulomatosis Circulatory System 0.904 0.74 – 1.11 0.326 109 1075 all phecode
446.5 Giant cell arteritis Circulatory System 0.877 0.691 – 1.11 0.282 79 749 all phecode
446.9 Arteritis NOS Circulatory System 1.04 0.915 – 1.17 0.577 289 2876 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.1 1.06 – 1.15 5.02e-06 2647 22765 all phecode
447.1 Stricture of artery Circulatory System 1.2 1.09 – 1.32 0.00012 523 5163 all phecode
447.7 Aortic ectasia Circulatory System 1.06 0.984 – 1.14 0.123 804 7938 all phecode
448 Disease of capillaries Circulatory System 0.847 0.797 – 0.9 8.33e-08 1237 12127 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.07 1.02 – 1.12 0.00443 2104 20985 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.03 0.954 – 1.11 0.444 738 7355 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.05 0.922 – 1.2 0.439 244 2437 all phecode
452 Other venous embolism and thrombosis Circulatory System 1.12 1.09 – 1.16 2.86e-13 4957 29867 all phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1.1 0.97 – 1.25 0.135 276 2747 all phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1.13 1.09 – 1.17 3.51e-10 3260 26940 all phecode
452.8 Postphlebitic syndrome Circulatory System 1.21 1.03 – 1.43 0.0222 154 1529 all phecode
453 Chronic venous hypertension Circulatory System 1.17 1.01 – 1.35 0.0317 220 2168 all phecode
454 Varicose veins Circulatory System 1.06 1.02 – 1.1 0.0064 2827 24555 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1.08 1.04 – 1.13 0.00028 2469 21426 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.09 1.04 – 1.15 0.00121 1565 15056 all phecode
455 Hemorrhoids Circulatory System 0.957 0.93 – 0.986 0.0034 5799 29818 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.11 1.07 – 1.15 8.62e-08 3097 24898 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.12 1.07 – 1.18 1.25e-06 2095 15309 all phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.19 1.05 – 1.33 0.00443 324 3221 all phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.12 1.07 – 1.18 2.26e-06 1973 14689 all phecode
458 Hypotension Circulatory System 1.11 1.07 – 1.14 7.93e-11 5091 32185 all phecode
458.1 Orthostatic hypotension Circulatory System 1.05 0.987 – 1.11 0.13 1344 12938 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.13 1.06 – 1.21 0.000108 1109 11012 all phecode
458.9 Hypotension NOS Circulatory System 1.11 1.07 – 1.15 2.81e-10 4618 31186 all phecode
459 Other disorders of circulatory system Circulatory System 1.09 1.06 – 1.12 1.52e-11 7825 34792 all phecode
459.1 Hemorrhage NOS Circulatory System 1.01 0.942 – 1.09 0.718 834 8215 all phecode
459.7 Blood vessel replaced Circulatory System 1.15 1.09 – 1.22 2.71e-06 1305 13023 all phecode
459.9 Circulatory disease NEC Circulatory System 1.1 1.07 – 1.13 5.18e-11 6706 33592 all phecode
464 Acute sinusitis Respiratory 0.969 0.939 – 1 0.0526 4792 32137 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.971 0.949 – 0.994 0.0145 9601 35915 all phecode
465.2 Acute pharyngitis Respiratory 0.948 0.92 – 0.977 0.000552 5310 32365 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.04 0.937 – 1.15 0.489 443 4428 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.924 0.879 – 0.971 0.00188 1797 17640 all phecode
471 Nasal polyps Respiratory 0.96 0.88 – 1.05 0.35 592 5881 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.957 0.911 – 1.01 0.0877 1797 16986 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1 0.963 – 1.04 0.933 2983 25244 all phecode
473.1 Chronic laryngitis Respiratory 1.14 0.892 – 1.45 0.299 68 674 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.996 0.915 – 1.08 0.928 628 6254 all phecode
473.4 Voice disturbance Respiratory 1 0.959 – 1.05 0.925 2336 21975 all phecode
474 Acute and chronic tonsillitis Respiratory 1.03 0.958 – 1.1 0.437 880 7892 all phecode
474.1 Acute tonsillitis Respiratory 0.93 0.829 – 1.04 0.222 335 3181 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.06 0.976 – 1.14 0.17 700 6445 all phecode
475 Chronic sinusitis Respiratory 0.964 0.933 – 0.996 0.0284 4378 27891 all phecode
475.9 Postnasal drip Respiratory 0.89 0.829 – 0.955 0.00113 922 9017 all phecode
476 Allergic rhinitis Respiratory 0.981 0.959 – 1 0.0761 12687 28117 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.07 1 – 1.14 0.0359 1150 11318 all phecode
478 Throat pain Respiratory 1.02 0.925 – 1.13 0.645 426 4195 all phecode
479 Other upper respiratory disease Respiratory 1.01 0.977 – 1.04 0.657 5627 28048 all phecode
480 Pneumonia Respiratory 1.08 1.05 – 1.11 5.9e-08 5947 37034 all phecode
480.1 Bacterial pneumonia Respiratory 1.06 0.994 – 1.13 0.0752 1155 11495 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.08 0.987 – 1.18 0.0962 568 5644 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.03 0.87 – 1.23 0.707 153 1523 all phecode
480.13 MRSA pneumonia Respiratory 1.19 0.982 – 1.43 0.0765 117 1165 all phecode
480.2 Viral pneumonia Respiratory 1.18 1.02 – 1.36 0.03 202 1992 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.02 0.864 – 1.2 0.846 159 1590 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.09 0.909 – 1.3 0.362 135 1312 all phecode
481 Influenza Respiratory 1.04 0.978 – 1.1 0.232 1355 13284 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.02 0.987 – 1.06 0.213 3412 29871 all phecode
495 Asthma Respiratory 1.13 1.11 – 1.16 1.18e-23 8671 33569 all phecode
495.1 Chronic obstructive asthma Respiratory 1.24 1.12 – 1.38 6.06e-05 397 3925 all phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 1.14 0.9 – 1.46 0.27 81 802 all phecode
495.2 Asthma with exacerbation Respiratory 1.08 1.02 – 1.14 0.00471 1629 16033 all phecode
496 Chronic airway obstruction Respiratory 1.2 1.17 – 1.24 1.03e-32 5343 28343 all phecode
496.1 Emphysema Respiratory 1.18 1.12 – 1.23 6.79e-12 2134 19414 all phecode
496.2 Chronic bronchitis Respiratory 1.25 1.21 – 1.3 3.95e-38 4128 26624 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.27 1.22 – 1.31 6.91e-38 3747 25467 all phecode
496.3 Bronchiectasis Respiratory 0.971 0.887 – 1.06 0.527 549 5453 all phecode
497 Bronchitis Respiratory 1.1 1.05 – 1.15 9.4e-05 1946 18824 all phecode
498 Acute bronchospasm Respiratory 1.29 1.17 – 1.42 2.75e-07 496 4943 all phecode
499 Cystic fibrosis Respiratory 0.918 0.776 – 1.09 0.32 151 1510 all phecode
500 Lung disease due to external agents Respiratory 1.1 1 – 1.2 0.039 557 5551 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.972 0.78 – 1.21 0.798 92 920 all phecode
500.2 Pneumoconiosis Respiratory 1.35 1.06 – 1.71 0.015 78 764 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.1 1.01 – 1.19 0.0311 634 6225 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.06 0.979 – 1.14 0.159 815 8076 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.21 1.12 – 1.3 5.06e-07 835 8243 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.07 0.983 – 1.17 0.116 595 5878 all phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 1.01 0.893 – 1.13 0.916 311 3084 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.14 1.08 – 1.2 8.51e-07 1638 15749 all phecode
506 Empyema and pneumothorax Respiratory 1.08 1.04 – 1.12 0.00022 2894 25235 all phecode
507 Pleurisy; pleural effusion Respiratory 1.13 1.09 – 1.18 8.65e-10 2916 26208 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.12 1.07 – 1.17 2.47e-07 2382 22588 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.14 1.11 – 1.18 7.28e-15 4032 29477 all phecode
509.1 Respiratory failure Respiratory 1.16 1.11 – 1.22 1.66e-09 1937 18949 all phecode
509.2 Respiratory insufficiency Respiratory 1.12 1.06 – 1.2 0.000239 1174 11679 all phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.1 1.05 – 1.16 2e-04 1689 16489 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.2 1.14 – 1.27 1.12e-12 1741 17249 all phecode
510 Other diseases of lung Respiratory 1.03 1 – 1.06 0.0356 5503 35907 all phecode
510.2 Lung transplant Respiratory 0.933 0.798 – 1.09 0.388 176 1757 all phecode
512 Other symptoms of respiratory system Respiratory 1.07 1.05 – 1.1 2.27e-13 18621 28154 all phecode
512.1 Wheezing Respiratory 1.22 1.16 – 1.3 1.82e-12 1409 13516 all phecode
512.2 Painful respiration Respiratory 1.03 0.987 – 1.08 0.173 2309 21263 all phecode
512.3 Abnormal chest sounds Respiratory 1.04 0.917 – 1.17 0.561 291 2845 all phecode
512.7 Shortness of breath Respiratory 1.13 1.1 – 1.16 4.19e-24 10034 28081 all phecode
512.8 Cough Respiratory 1.06 1.03 – 1.08 1.24e-05 9501 28148 all phecode
512.9 Other dyspnea Respiratory 1.11 1.08 – 1.14 8.1e-19 10804 28104 all phecode
513 Respiratory abnormalities Respiratory 1.12 1.1 – 1.14 2.87e-26 12932 33822 all phecode
513.3 Hypoventilation Respiratory 1.15 1.07 – 1.24 8.53e-05 880 8646 all phecode
513.31 Apnea Respiratory 1.06 0.958 – 1.17 0.273 462 4607 all phecode
513.32 Orthopnea Respiratory 1.13 0.983 – 1.3 0.0848 220 2160 all phecode
513.4 Hyperventilation Respiratory 1.26 1.14 – 1.38 2.15e-06 515 5124 all phecode
513.8 Disorders of diaphragm Respiratory 1.03 0.903 – 1.18 0.642 258 2557 all phecode
514 Abnormal findings examination of lungs Respiratory 1.04 1.01 – 1.07 0.00775 5365 34834 all phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 1.02 0.894 – 1.16 0.775 258 2580 all phecode
514.2 Solitary pulmonary nodule Respiratory 1.03 0.989 – 1.07 0.167 3018 27338 all phecode
516 Abnormal sputum Respiratory 1.09 1.01 – 1.18 0.0263 735 7332 all phecode
516.1 Hemoptysis Respiratory 1.11 1.02 – 1.21 0.0195 611 6080 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.07 1.05 – 1.1 2.39e-07 6458 39057 all phecode
519.1 Tracheostomy complications Respiratory 1.23 1.07 – 1.42 0.00365 214 2136 all phecode
519.2 Respiratory complications Respiratory 1.07 0.966 – 1.18 0.199 445 4430 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.03 0.974 – 1.08 0.319 1588 15787 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.08 1.04 – 1.11 3.47e-06 4706 34489 all phecode
520 Disorders of tooth development Digestive 1.1 0.99 – 1.23 0.0742 369 3690 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.27 1.08 – 1.49 0.00412 165 1642 all phecode
520.2 Disturbances in tooth eruption Digestive 1.03 0.894 – 1.18 0.699 218 2172 all phecode
521 Diseases of hard tissues of teeth Digestive 1.13 1.06 – 1.22 0.000335 898 8954 all phecode
521.1 Dental caries Digestive 1.15 1.07 – 1.24 0.00011 837 8349 all phecode
521.2 Dental abrasion, erosion and attrition Digestive 1.07 0.813 – 1.42 0.614 52 510 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.2 1.1 – 1.32 6.27e-05 535 5340 all phecode
522.5 Periapical abscess Digestive 1.22 1.11 – 1.35 5.55e-05 459 4583 all phecode
523 Gingival and periodontal diseases Digestive 1.16 1.07 – 1.25 0.000163 718 7180 all phecode
523.1 Gingivitis Digestive 1.04 0.877 – 1.23 0.659 142 1418 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.19 1.07 – 1.33 0.00132 364 3636 all phecode
523.31 Acute periodontitis Digestive 1.19 1.06 – 1.34 0.00379 311 3109 all phecode
523.32 Chronic periodontitis Digestive 1.17 0.971 – 1.41 0.0978 122 1204 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.905 0.811 – 1.01 0.0775 363 3630 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.872 0.76 – 1 0.0522 220 2200 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.18 1.11 – 1.26 3.67e-07 1039 10382 all phecode
525.1 Loss of teeth or edentulism Digestive 1.15 1.03 – 1.28 0.0105 374 3731 all phecode
526 Diseases of the jaws Digestive 0.949 0.911 – 0.988 0.0116 2680 26455 all phecode
526.1 Cysts of the jaws Digestive 0.907 0.795 – 1.04 0.148 247 2470 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.847 0.739 – 0.971 0.0172 241 2383 all phecode
526.4 Temporomandibular joint disorders Digestive 0.914 0.866 – 0.965 0.00121 1504 15025 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.93 0.875 – 0.989 0.0201 1187 11858 all phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 0.889 0.822 – 0.961 0.00296 741 7400 all phecode
526.5 Inflammatory conditions of jaw Digestive 1.08 0.959 – 1.23 0.198 287 2864 all phecode
526.8 Exostosis of jaw Digestive 1.26 0.928 – 1.71 0.139 53 521 all phecode
526.9 Jaw disease NOS Digestive 0.995 0.903 – 1.09 0.912 487 4867 all phecode
527 Diseases of the salivary glands Digestive 1.01 0.961 – 1.06 0.705 1781 17771 all phecode
527.1 Hypertrophy of salivary gland Digestive 0.924 0.712 – 1.2 0.552 58 579 all phecode
527.2 Sialoadenitis Digestive 1.02 0.919 – 1.14 0.69 394 3936 all phecode
527.7 Disturbance of salivary secretion Digestive 0.989 0.923 – 1.06 0.751 952 9481 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.13 0.991 – 1.29 0.0688 254 2540 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.966 0.928 – 1.01 0.104 2643 26197 all phecode
528.1 Stomatitis and mucositis Digestive 0.939 0.865 – 1.02 0.13 668 6657 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.06 0.917 – 1.22 0.436 211 2110 all phecode
528.12 Oral aphthae Digestive 0.891 0.772 – 1.03 0.116 215 2137 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.11 0.973 – 1.27 0.121 235 2338 all phecode
528.4 Cysts of oral soft tissues Digestive 0.774 0.641 – 0.934 0.00764 124 1229 all phecode
528.41 Cyst of the salivary gland Digestive 0.857 0.678 – 1.08 0.198 77 760 all phecode
528.5 Diseases of lips Digestive 0.99 0.898 – 1.09 0.846 462 4602 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1 0.838 – 1.2 0.987 137 1370 all phecode
528.7 Sialolithiasis Digestive 1.03 0.875 – 1.22 0.711 163 1623 all phecode
529 Diseases and other conditions of the tongue Digestive 1.03 0.949 – 1.12 0.483 690 6878 all phecode
529.1 Glossitis Digestive 0.964 0.799 – 1.16 0.697 129 1281 all phecode
529.6 Glossodynia Digestive 1.09 0.931 – 1.28 0.274 168 1652 all phecode
530 Diseases of esophagus Digestive 1.13 1.1 – 1.15 4.24e-31 17081 27931 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.13 1.1 – 1.15 4.08e-31 16572 27931 all phecode
530.11 GERD Digestive 1.13 1.11 – 1.15 5.74e-32 16143 27929 all phecode
530.12 Ulcer of esophagus Digestive 1.14 1.02 – 1.26 0.0188 400 3983 all phecode
530.13 Barrett's esophagus Digestive 1.18 1.09 – 1.28 1.98e-05 762 7584 all phecode
530.14 Reflux esophagitis Digestive 1.09 1.03 – 1.14 0.000958 1900 17495 all phecode
530.15 Eosinophilic esophagitis Digestive 1.1 0.96 – 1.27 0.165 221 2210 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.12 1.04 – 1.22 0.00471 651 6473 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.05 0.976 – 1.12 0.206 911 8971 all phecode
530.5 Disorders of esophageal motility Digestive 1.11 1.02 – 1.22 0.0202 548 5432 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.941 0.778 – 1.14 0.534 129 1265 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.99 0.789 – 1.24 0.929 82 812 all phecode
530.9 Heartburn Digestive 1.09 1.04 – 1.16 0.00101 1519 14928 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.11 1.06 – 1.16 9.91e-06 2073 20617 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.991 0.89 – 1.1 0.865 391 3883 all phecode
531.2 Gastric ulcer Digestive 1.15 1.08 – 1.22 1.12e-05 1201 11970 all phecode
531.3 Duodenal ulcer Digestive 1.04 0.942 – 1.14 0.447 467 4640 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.1 1.02 – 1.18 0.017 804 8018 all phecode
531.5 Gastrojejunal ulcer Digestive 1.27 1.07 – 1.51 0.00568 150 1500 all phecode
532 Dysphagia Digestive 1.11 1.07 – 1.14 6.03e-11 5585 26852 all phecode
535 Gastritis and duodenitis Digestive 1.06 1.01 – 1.1 0.00757 2799 27335 all phecode
535.1 Acute gastritis Digestive 1.13 1.07 – 1.21 6.51e-05 1178 11750 all phecode
535.2 Atrophic gastritis Digestive 0.991 0.885 – 1.11 0.88 344 3413 all phecode
535.6 Duodenitis Digestive 1.04 0.925 – 1.16 0.539 334 3337 all phecode
535.8 Other specified gastritis Digestive 1.01 0.93 – 1.1 0.794 638 6354 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.997 0.94 – 1.06 0.925 1255 12511 all phecode
536 Disorders of function of stomach Digestive 1.02 0.979 – 1.06 0.37 2911 27685 all phecode
536.3 Gastroparesis Digestive 1.08 1 – 1.17 0.045 706 6901 all phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.03 0.926 – 1.14 0.622 407 4059 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.01 0.963 – 1.05 0.744 2150 21094 all phecode
537 Other disorders of stomach and duodenum Digestive 1.08 1.04 – 1.12 5.07e-05 3183 30048 all phecode
537.1 Lesions of stomach and duodenum Digestive 1.17 1 – 1.37 0.0498 173 1725 all phecode
539 Bariatric surgery Digestive 1.84 1.74 – 1.94 1.37e-98 1509 15074 all phecode
540 Appendiceal conditions Digestive 0.986 0.897 – 1.08 0.778 495 4948 all phecode
540.1 Appendicitis Digestive 0.954 0.861 – 1.06 0.372 425 4239 all phecode
540.11 Acute appendicitis Digestive 0.942 0.842 – 1.06 0.304 353 3511 all phecode
550 Abdominal hernia Digestive 1.05 1.02 – 1.07 0.00118 6768 37731 all phecode
550.1 Inguinal hernia Digestive 0.81 0.77 – 0.853 4.7e-16 1744 16488 all phecode
550.2 Diaphragmatic hernia Digestive 1.06 1.02 – 1.11 0.00308 2817 25849 all phecode
550.3 Femoral hernia Digestive 0.762 0.636 – 0.913 0.00321 131 1291 all phecode
550.4 Umbilical hernia Digestive 1.08 1.02 – 1.14 0.00867 1313 13110 all phecode
550.5 Ventral hernia Digestive 1.18 1.13 – 1.24 1.24e-13 2241 22163 all phecode
550.6 Incisional hernia Digestive 1.2 1.13 – 1.27 1.02e-09 1313 13111 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.05 0.991 – 1.1 0.0991 1536 15153 all phecode
555.1 Regional enteritis Digestive 1.08 1.01 – 1.16 0.0237 919 9095 all phecode
555.2 Ulcerative colitis Digestive 0.973 0.908 – 1.04 0.43 937 9315 all phecode
555.21 Ulcerative colitis (chronic) Digestive 0.897 0.818 – 0.984 0.021 537 5315 all phecode
556 Ulceration of the lower GI tract Digestive 1.05 0.967 – 1.15 0.241 632 6267 all phecode
556.1 Ulceration of intestine Digestive 1.06 0.966 – 1.16 0.222 551 5451 all phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 0.999 0.865 – 1.15 0.993 214 2093 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.21 1.15 – 1.27 2.14e-13 1716 16490 all phecode
557.1 Celiac disease Digestive 0.956 0.863 – 1.06 0.393 421 4026 all phecode
558 Noninfectious gastroenteritis Digestive 1.04 1 – 1.08 0.027 3458 26408 all phecode
559 Ileostomy status Digestive 1.04 0.968 – 1.11 0.311 957 9565 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.06 1.02 – 1.1 0.0024 3004 24851 all phecode
560.1 Paralytic ileus Digestive 1.06 1 – 1.11 0.0375 1627 15714 all phecode
560.2 Impaction of intestine Digestive 1.04 0.934 – 1.16 0.467 387 3779 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.949 0.833 – 1.08 0.437 266 2647 all phecode
560.4 Other intestinal obstruction Digestive 1.07 1.01 – 1.12 0.0165 1651 16170 all phecode
561 Symptoms involving digestive system Digestive 0.995 0.954 – 1.04 0.803 2608 21766 all phecode
562 Diverticulosis and diverticulitis Digestive 1.02 0.99 – 1.05 0.192 6295 23431 all phecode
562.1 Diverticulosis Digestive 1.02 0.99 – 1.05 0.2 6246 23383 all phecode
562.2 Diverticulitis Digestive 1.06 1.01 – 1.12 0.0308 1611 15162 all phecode
564 Functional digestive disorders Digestive 1.04 1.02 – 1.07 0.000253 11411 28676 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.02 0.978 – 1.05 0.421 3457 22266 all phecode
564.9 Personal history of diseases of digestive system Digestive 1.07 1.03 – 1.12 0.000302 3074 25861 all phecode
565 Anal and rectal conditions Digestive 0.97 0.935 – 1.01 0.104 3355 30757 all phecode
565.1 Anal and rectal polyp Digestive 0.987 0.931 – 1.05 0.671 1305 12649 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.15 1.08 – 1.21 2.74e-06 1364 13616 all phecode
568 Other disorders of peritoneum Digestive 1.14 1.08 – 1.2 3.93e-07 1705 17038 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.15 1.09 – 1.22 2.69e-06 1247 12468 all phecode
569 Other disorders of intestine Digestive 1.05 1.03 – 1.08 6.83e-05 8079 35231 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1 0.892 – 1.13 0.96 326 3260 all phecode
569.2 Gastrointestinal complications Digestive 1.19 1.12 – 1.26 1.64e-09 1395 13933 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.13 1.09 – 1.17 3.96e-14 4610 32562 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.13 1.09 – 1.17 3.9e-13 4342 32234 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.16 1.09 – 1.24 8.82e-06 1018 10095 all phecode
571.6 Primary biliary cirrhosis Digestive 0.966 0.827 – 1.13 0.66 179 1790 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.14 1.06 – 1.22 0.000274 950 9498 all phecode
571.81 Portal hypertension Digestive 1.09 0.997 – 1.19 0.0578 573 5730 all phecode
572 Ascites (non malignant) Digestive 1.07 1.03 – 1.12 0.00217 2278 22675 all phecode
573 Other disorders of liver Digestive 1.08 1.05 – 1.11 4.64e-07 5599 33620 all phecode
573.1 Chronic passive congestion of liver Digestive 1.23 1.04 – 1.47 0.0181 136 1359 all phecode
573.2 Liver replaced by transplant Digestive 1.05 0.932 – 1.19 0.406 292 2920 all phecode
573.3 Hepatomegaly Digestive 1.2 1.09 – 1.31 0.00024 470 4700 all phecode
573.4 Acute and subacute necrosis of liver Digestive 0.983 0.873 – 1.11 0.772 316 3149 all phecode
573.5 Jaundice (not of newborn) Digestive 1.04 0.969 – 1.11 0.295 958 9496 all phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.05 1.01 – 1.09 0.0207 2756 26470 all phecode
573.7 Abnormal results of function study of liver Digestive 1.04 1 – 1.09 0.0278 3018 27774 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.05 1.01 – 1.08 0.00433 4679 33866 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.12 1.07 – 1.16 1.39e-08 3177 30809 all phecode
574.1 Cholelithiasis Digestive 1.12 1.08 – 1.16 2.38e-08 2924 28874 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.23 1.1 – 1.37 0.00038 342 3412 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.09 0.994 – 1.19 0.0673 553 5501 all phecode
574.2 Calculus of bile duct Digestive 1.04 0.967 – 1.12 0.288 852 8503 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.14 1.06 – 1.23 0.000315 822 8181 all phecode
575 Other biliary tract disease Digestive 1.05 1 – 1.09 0.046 2266 22555 all phecode
575.1 Cholangitis Digestive 0.975 0.872 – 1.09 0.659 354 3530 all phecode
575.2 Obstruction of bile duct Digestive 1.09 1.01 – 1.19 0.0364 621 6201 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.962 0.834 – 1.11 0.6 207 2063 all phecode
575.7 Other disorders of gallbladder Digestive 1.03 0.958 – 1.1 0.456 939 9382 all phecode
575.8 Other disorders of biliary tract Digestive 1.06 0.999 – 1.13 0.0539 1154 11523 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.09 0.956 – 1.24 0.201 260 2600 all phecode
577 Diseases of pancreas Digestive 1.07 1.02 – 1.11 0.00574 2225 22106 all phecode
577.1 Acute pancreatitis Digestive 1.13 1.06 – 1.2 6.95e-05 1212 12110 all phecode
577.2 Chronic pancreatitis Digestive 1.2 1.09 – 1.32 2e-04 495 4950 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.03 0.938 – 1.12 0.568 570 5601 all phecode
578 Gastrointestinal hemorrhage Digestive 1.03 1 – 1.07 0.0343 4554 37045 all phecode
578.1 Hematemesis Digestive 1.13 1.03 – 1.24 0.00987 485 4842 all phecode
578.2 Blood in stool Digestive 1.05 1.01 – 1.09 0.0195 2743 26554 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.03 0.987 – 1.08 0.166 2210 21750 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.06 1.01 – 1.12 0.0251 1562 15345 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.1 1.06 – 1.13 1.66e-08 4431 34209 all phecode
579.2 Splenomegaly Digestive 1.22 1.13 – 1.32 5.74e-07 730 7262 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1 0.946 – 1.06 1 1410 13877 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.24 1.18 – 1.31 2.42e-17 1881 15516 all phecode
580.1 Glomerulonephritis Genitourinary 1.27 1.15 – 1.41 4.88e-06 401 3992 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.18 0.991 – 1.4 0.0627 146 1440 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.46 1.2 – 1.77 0.000162 114 1128 all phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.03 0.796 – 1.34 0.816 61 600 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.39 1.23 – 1.58 2.61e-07 277 2760 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.25 1.09 – 1.44 0.00126 221 2193 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.24 1.18 – 1.32 2.6e-14 1502 11930 all phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.31 1.22 – 1.41 2.16e-14 992 7228 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.15 1.06 – 1.25 0.000697 683 6612 all phecode
580.4 Renal sclerosis, NOS Genitourinary 1.22 1.09 – 1.37 0.000848 340 3400 all phecode
585 Renal failure Genitourinary 1.21 1.17 – 1.24 1.72e-42 7470 32340 all phecode
585.1 Acute renal failure Genitourinary 1.21 1.17 – 1.25 4.47e-28 4265 27230 all phecode
585.2 Renal failure NOS Genitourinary 1.24 1.15 – 1.34 9.28e-09 832 8162 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.22 1.18 – 1.26 1.38e-37 5580 29470 all phecode
585.31 Renal dialysis Genitourinary 1.21 1.12 – 1.31 8.02e-07 747 7423 all phecode
585.32 End stage renal disease Genitourinary 1.27 1.19 – 1.36 1.05e-12 1007 9783 all phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.25 1.2 – 1.3 6.28e-28 3209 21312 all phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.25 1.17 – 1.34 9.07e-11 977 9190 all phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.25 1.18 – 1.33 7.56e-13 1227 11191 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.12 1.09 – 1.15 7.59e-18 7628 34189 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.11 0.991 – 1.24 0.0701 349 3480 all phecode
586.11 Small kidney Genitourinary 1.14 0.985 – 1.31 0.0802 210 2093 all phecode
586.12 Vesicoureteral reflux Genitourinary 1.09 0.908 – 1.3 0.366 136 1360 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.05 0.989 – 1.11 0.11 1381 12912 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.13 0.972 – 1.32 0.113 187 1862 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.04 0.987 – 1.09 0.154 1821 17115 all phecode
587 Kidney replaced by transpant Genitourinary 1.14 1.06 – 1.23 0.00039 819 8134 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.22 1.14 – 1.31 8.68e-09 976 9389 all phecode
588.1 Renal osteodystrophy Genitourinary 1.12 0.991 – 1.27 0.0689 290 2900 all phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.21 1.12 – 1.31 1.1e-06 755 7275 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.18 1.1 – 1.26 1.58e-06 1007 9834 all phecode
590 Pyelonephritis Genitourinary 1.12 1.06 – 1.18 9.45e-05 1461 14350 all phecode
591 Urinary tract infection Genitourinary 1.03 1 – 1.05 0.0272 9873 32513 all phecode
592 Cystitis and urethritis Genitourinary 1.01 0.972 – 1.05 0.603 3038 24207 all phecode
592.1 Cystitis Genitourinary 1.01 0.974 – 1.06 0.497 2880 23279 all phecode
592.11 Acute cystitis Genitourinary 1.01 0.964 – 1.07 0.589 1783 16452 all phecode
592.12 Chronic cystitis Genitourinary 1.04 0.907 – 1.2 0.56 239 2343 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.954 0.862 – 1.06 0.364 431 4310 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.989 0.857 – 1.14 0.885 210 2093 all phecode
593 Hematuria Genitourinary 1.03 1 – 1.06 0.0495 4859 32063 all phecode
593.1 Gross hematuria Genitourinary 1.02 0.965 – 1.07 0.528 1585 14824 all phecode
593.2 Microscopic hematuria Genitourinary 1.02 0.951 – 1.08 0.639 1049 10301 all phecode
594 Urinary calculus Genitourinary 1.08 1.05 – 1.11 4.97e-09 6707 38209 all phecode
594.1 Calculus of kidney Genitourinary 1.09 1.06 – 1.12 2.69e-09 6273 38051 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.08 0.965 – 1.2 0.19 366 3638 all phecode
594.3 Calculus of ureter Genitourinary 1.08 1.02 – 1.14 0.011 1361 13561 all phecode
594.8 Renal colic Genitourinary 1.09 0.972 – 1.21 0.147 356 3560 all phecode
595 Hydronephrosis Genitourinary 1.06 1 – 1.11 0.0346 1670 16658 all phecode
596 Other disorders of bladder Genitourinary 0.996 0.958 – 1.03 0.823 3074 28020 all phecode
596.1 Bladder neck obstruction Genitourinary 0.969 0.872 – 1.08 0.56 400 3942 all phecode
596.5 Functional disorders of bladder Genitourinary 1 0.95 – 1.05 0.994 1719 17049 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.983 0.926 – 1.04 0.58 1211 11998 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.943 0.87 – 1.02 0.158 661 6537 all phecode
597.2 Urinary complications NEC Genitourinary 1.01 0.949 – 1.08 0.697 1049 10479 all phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.11 0.956 – 1.3 0.169 189 1873 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.11 0.925 – 1.33 0.264 138 1356 all phecode
598.4 Other cells and casts in urine Genitourinary 1.08 0.889 – 1.31 0.445 122 1192 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.986 – 1.03 0.531 14168 30681 all phecode
599.1 Urinary obstruction Genitourinary 0.877 0.81 – 0.949 0.00112 728 6861 all phecode
599.2 Retention of urine Genitourinary 0.996 0.965 – 1.03 0.78 5034 28305 all phecode
599.3 Dysuria Genitourinary 0.994 0.962 – 1.03 0.702 4397 27849 all phecode
599.4 Urinary incontinence Genitourinary 1.03 1 – 1.07 0.0286 5599 26960 all phecode
599.5 Frequency of urination and polyuria Genitourinary 0.981 0.952 – 1.01 0.208 5498 28723 all phecode
599.6 Oliguria and anuria Genitourinary 1.11 1.02 – 1.21 0.018 599 5902 all phecode
599.7 Urethral discharge Genitourinary 0.991 0.819 – 1.2 0.926 118 1175 all phecode
599.8 Other symptoms involving urinary system Genitourinary 0.986 0.956 – 1.02 0.352 5446 27963 all phecode
599.9 Other abnormality of urination Genitourinary 0.963 0.926 – 1 0.0549 3041 24877 all phecode
600 Hyperplasia of prostate Genitourinary 0.925 0.89 – 0.962 0.000111 4063 11364 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.945 0.886 – 1.01 0.0869 1044 9665 all phecode
601.1 Prostatitis Genitourinary 0.82 0.745 – 0.903 5.32e-05 477 4596 all phecode
601.11 Acute prostatitis Genitourinary 0.964 0.796 – 1.17 0.712 124 1200 all phecode
601.12 Chronic prostatitis Genitourinary 0.916 0.739 – 1.14 0.427 95 943 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.06 0.955 – 1.18 0.276 389 3822 all phecode
601.4 Balanoposthitis Genitourinary 0.93 0.77 – 1.12 0.45 127 1224 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.11 0.941 – 1.3 0.223 161 1591 all phecode
602 Other disorders of prostate Genitourinary 0.872 0.779 – 0.975 0.0162 361 3399 all phecode
602.3 Dysplasia of prostate Genitourinary 1.01 0.8 – 1.28 0.923 77 730 all phecode
603 Other disorders of testis Genitourinary 0.99 0.897 – 1.09 0.845 440 4354 all phecode
603.1 Hydrocele Genitourinary 0.976 0.864 – 1.1 0.695 293 2882 all phecode
603.2 Spermatocele Genitourinary 0.901 0.766 – 1.06 0.213 156 1539 all phecode
604 Disorders of penis Genitourinary 0.94 0.868 – 1.02 0.129 685 6748 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.22 1.03 – 1.45 0.0195 155 1540 all phecode
604.3 Peyronie's disease Genitourinary 0.832 0.722 – 0.958 0.0106 215 2132 all phecode
605 Erectile dysfunction [ED] Genitourinary 0.96 0.924 – 0.997 0.0354 3776 12700 all phecode
608 Other disorders of male genital organs Genitourinary 0.957 0.909 – 1.01 0.103 1645 13758 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.885 0.8 – 0.978 0.017 424 4196 all phecode
609.1 Infertility, male Genitourinary 0.931 0.828 – 1.05 0.232 302 2992 all phecode
609.11 Azoospermia and oligospermia Genitourinary 1.19 0.962 – 1.48 0.108 95 950 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.778 0.657 – 0.92 0.00341 154 1519 all phecode
610 Benign mammary dysplasias Genitourinary 0.908 0.874 – 0.942 3.66e-07 3683 16548 all phecode
610.1 Cystic mastopathy Genitourinary 0.9 0.853 – 0.949 0.000102 1633 14191 all phecode
610.2 Fibroadenosis of breast Genitourinary 0.869 0.666 – 1.13 0.303 60 600 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.892 0.856 – 0.93 7.42e-08 2837 16430 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.9 0.848 – 0.956 0.00066 1269 12191 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.906 0.879 – 0.934 1.94e-10 6067 18690 all phecode
611.1 Abnormal mammogram Genitourinary 0.887 0.858 – 0.918 2.58e-12 4980 16120 all phecode
611.11 Mammographic microcalcification Genitourinary 0.825 0.774 – 0.88 4.96e-09 1122 10394 all phecode
611.3 Lump or mass in breast Genitourinary 0.903 0.87 – 0.937 8.41e-08 3549 18572 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.976 0.914 – 1.04 0.47 1051 10425 all phecode
612.1 Galactorrhea Genitourinary 1.09 0.91 – 1.31 0.351 139 1390 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.995 0.923 – 1.07 0.905 800 7962 all phecode
612.3 Congenital anomalies of breast Genitourinary 0.692 0.54 – 0.887 0.00361 83 810 all phecode
613 Other nonmalignant breast conditions Genitourinary 0.959 0.926 – 0.994 0.0205 3897 22072 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.02 0.936 – 1.11 0.658 593 5874 all phecode
613.5 Mastodynia Genitourinary 0.969 0.92 – 1.02 0.241 1675 16203 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.893 0.831 – 0.959 0.00188 883 8754 all phecode
613.8 Other specified disorders of breast Genitourinary 0.897 0.837 – 0.962 0.00231 932 9248 all phecode
613.9 Breast disorder NOS Genitourinary 0.916 0.866 – 0.968 0.00189 1465 14174 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.987 0.952 – 1.02 0.474 3715 19647 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.02 0.908 – 1.14 0.747 337 3370 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.07 0.967 – 1.18 0.2 478 4773 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.23 0.98 – 1.54 0.0743 94 933 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.941 0.804 – 1.1 0.454 186 1842 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.01 0.881 – 1.16 0.879 246 2460 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.04 0.887 – 1.23 0.6 165 1639 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.974 0.937 – 1.01 0.186 3180 19539 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.03 0.9 – 1.17 0.69 264 2640 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.964 0.925 – 1.01 0.0849 2732 18924 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.11 0.926 – 1.33 0.257 132 1311 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.09 0.943 – 1.25 0.254 225 2244 all phecode
615 Endometriosis Genitourinary 0.978 0.927 – 1.03 0.413 1585 14666 all phecode
618 Genital prolapse Genitourinary 0.96 0.916 – 1.01 0.0856 2079 17915 all phecode
618.1 Prolapse of vaginal walls Genitourinary 0.926 0.875 – 0.98 0.00764 1408 13456 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.92 0.84 – 1.01 0.0724 542 5390 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.898 0.796 – 1.01 0.0793 317 3162 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.03 0.936 – 1.14 0.508 441 4394 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.984 0.954 – 1.01 0.304 5728 18687 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.02 0.965 – 1.09 0.427 1233 12082 all phecode
619.2 Disorders of uterus, NEC Genitourinary 0.964 0.883 – 1.05 0.409 591 5897 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.958 0.871 – 1.05 0.378 483 4823 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.984 0.943 – 1.03 0.473 2525 18404 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.01 0.949 – 1.07 0.763 1189 11717 all phecode
620 Dysplasia of female genital organs Genitourinary 1.05 0.945 – 1.16 0.372 395 3950 all phecode
620.1 Dysplasia of cervix Genitourinary 1.04 0.889 – 1.22 0.628 178 1780 all phecode
621 Endometrial hyperplasia Genitourinary 1.12 1.01 – 1.24 0.0303 437 4370 all phecode
622 Polyp of female genital organs Genitourinary 0.955 0.903 – 1.01 0.101 1449 14264 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.971 0.911 – 1.03 0.351 1132 11189 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.893 0.807 – 0.988 0.0286 445 4444 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.02 0.944 – 1.09 0.67 824 8165 all phecode
624 Symptoms involving female genital tract Genitourinary 0.975 0.921 – 1.03 0.393 1348 12518 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.919 0.797 – 1.06 0.248 216 2155 all phecode
624.2 Atrophy of female genital tract Genitourinary 1.1 0.839 – 1.44 0.495 64 615 all phecode
624.9 stress incontinence, female Genitourinary 1.03 0.984 – 1.08 0.195 1935 15408 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.982 0.952 – 1.01 0.25 5653 17303 all phecode
625.1 Dyspareunia Genitourinary 0.94 0.885 – 0.998 0.0417 1267 12474 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.991 0.96 – 1.02 0.566 5940 15585 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.995 0.96 – 1.03 0.798 4315 14604 all phecode
626.11 Absent or infrequent menstruation Genitourinary 1.03 0.963 – 1.1 0.404 1062 8531 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.02 0.975 – 1.07 0.348 2097 11991 all phecode
626.13 Irregular menstrual cycle Genitourinary 0.994 0.946 – 1.04 0.803 1957 12265 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.991 0.926 – 1.06 0.791 970 8996 all phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.997 0.897 – 1.11 0.959 394 3789 all phecode
626.2 Dysmenorrhea Genitourinary 1.03 0.971 – 1.09 0.332 1373 9857 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.953 0.85 – 1.07 0.409 336 3308 all phecode
626.8 Infertility, female Genitourinary 0.95 0.882 – 1.02 0.181 817 6741 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.922 0.891 – 0.955 4.87e-06 4560 14557 all phecode
627.1 Postmenopausal bleeding Genitourinary 0.943 0.886 – 1.01 0.0714 1146 10338 all phecode
627.2 Symptomatic menopause Genitourinary 0.906 0.869 – 0.944 2.55e-06 3017 13763 all phecode
627.21 Symptomatic artificial menopause Genitourinary 0.886 0.745 – 1.05 0.17 152 1514 all phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.759 0.677 – 0.852 2.64e-06 356 3513 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.875 0.817 – 0.936 0.000116 997 9484 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.953 0.852 – 1.07 0.397 361 3580 all phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.866 0.768 – 0.976 0.0185 309 3082 all phecode
628 Ovarian cyst Genitourinary 0.997 0.95 – 1.05 0.917 1945 13838 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.988 0.918 – 1.06 0.742 826 8047 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.954 0.84 – 1.08 0.467 273 2715 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.1 0.903 – 1.34 0.348 117 1170 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.897 0.821 – 0.98 0.0166 563 5309 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.902 0.808 – 1.01 0.0671 370 3629 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.865 0.764 – 0.979 0.0216 288 2850 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.952 0.892 – 1.02 0.14 1080 7870 all phecode
636.1 Threatened premature labor Pregnancy Complications 0.925 0.831 – 1.03 0.151 380 3799 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.956 0.845 – 1.08 0.481 288 2868 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.965 0.873 – 1.07 0.486 441 4365 all phecode
636.8 Cervical incompetence Pregnancy Complications 1.05 0.828 – 1.33 0.7 77 770 all phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.18 0.945 – 1.49 0.142 85 850 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.03 0.941 – 1.12 0.565 585 5725 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.02 0.904 – 1.15 0.755 302 3013 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.12 0.984 – 1.28 0.0841 252 2506 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.13 0.937 – 1.37 0.196 119 1190 all phecode
644 Anemia during pregnancy Pregnancy Complications 1.07 0.927 – 1.23 0.358 224 2224 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.02 0.947 – 1.1 0.61 855 6531 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.925 0.803 – 1.07 0.282 211 2093 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1 0.873 – 1.16 0.951 222 2213 all phecode
647.3 Major puerperal infection Pregnancy Complications 1.11 0.861 – 1.44 0.414 65 650 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.966 0.909 – 1.03 0.273 1275 8010 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.03 0.951 – 1.12 0.436 649 5687 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.987 0.904 – 1.08 0.76 587 5463 all phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.992 0.854 – 1.15 0.913 207 2055 all phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 0.994 0.857 – 1.15 0.938 204 2040 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.925 0.877 – 0.977 0.00483 1624 10064 all phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 0.931 0.854 – 1.01 0.0999 616 5533 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.02 0.953 – 1.1 0.534 898 7014 all phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 1.09 0.851 – 1.4 0.484 66 660 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.948 0.882 – 1.02 0.143 887 6802 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.04 0.908 – 1.18 0.594 236 2351 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.15 0.974 – 1.35 0.1 158 1580 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.838 0.719 – 0.977 0.0239 184 1814 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.13 1.1 – 1.16 8.99e-19 6500 38394 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.04 0.98 – 1.1 0.198 1256 11462 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.12 1.05 – 1.2 0.000663 1007 9981 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.16 1.11 – 1.22 1.64e-10 2123 19952 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.17 1.12 – 1.23 3.36e-12 2252 20944 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.17 1.12 – 1.23 2.73e-10 1820 16893 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.21 1.15 – 1.28 1.62e-12 1572 15588 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.11 1.06 – 1.16 2.65e-06 2257 21750 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.1 1 – 1.2 0.0472 558 5504 all phecode
686.2 Impetigo Dermatologic 1.04 0.939 – 1.16 0.433 414 4117 all phecode
686.3 Pilonidal cyst Dermatologic 1.17 0.992 – 1.38 0.0626 160 1594 all phecode
686.4 Pyogenic granuloma Dermatologic 0.999 0.847 – 1.18 0.99 158 1570 all phecode
686.5 Pyoderma Dermatologic 1.27 0.971 – 1.67 0.0809 63 630 all phecode
687 Symptoms affecting skin Dermatologic 0.967 0.918 – 1.02 0.204 1690 16343 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.998 0.972 – 1.03 0.91 7007 34623 all phecode
687.3 Changes in skin texture Dermatologic 1.07 0.968 – 1.19 0.18 415 4121 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.05 1.02 – 1.08 0.000956 6375 34216 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.927 0.905 – 0.949 3.11e-10 9311 37335 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.895 0.868 – 0.923 1.55e-12 5184 31581 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.895 0.868 – 0.923 1.74e-12 5174 31553 all phecode
691 Congenital anomalies of skin Dermatologic 0.978 0.893 – 1.07 0.629 541 5337 all phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 1 0.771 – 1.31 0.98 62 613 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.902 0.859 – 0.948 3.89e-05 1861 17936 all phecode
694.1 Vitiligo Dermatologic 1.05 0.88 – 1.26 0.58 137 1347 all phecode
694.2 Other dyschromia Dermatologic 0.894 0.849 – 0.941 2.09e-05 1674 16183 all phecode
694.3 Vascular disorders of skin Dermatologic 0.981 0.779 – 1.24 0.871 82 819 all phecode
695 Erythematous conditions Dermatologic 1.01 0.973 – 1.04 0.697 4120 30247 all phecode
695.1 Toxic erythema Dermatologic 1.12 0.877 – 1.42 0.374 70 688 all phecode
695.2 Bullous dermatoses Dermatologic 0.937 0.744 – 1.18 0.582 85 805 all phecode
695.3 Rosacea Dermatologic 0.89 0.847 – 0.935 4.49e-06 1816 17663 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.04 0.961 – 1.13 0.314 672 6686 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.1 0.96 – 1.25 0.172 247 2437 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.04 0.957 – 1.13 0.35 637 6337 all phecode
695.7 Prurigo and Lichen Dermatologic 0.968 0.889 – 1.06 0.465 605 5986 all phecode
695.8 Other specified erythematous conditions Dermatologic 1.15 1.07 – 1.24 0.000291 812 7980 all phecode
695.81 Erythema nodosum Dermatologic 0.857 0.645 – 1.14 0.288 55 550 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.11 1.03 – 1.21 0.00794 679 6756 all phecode
696 Psoriasis and related disorders Dermatologic 1.02 0.959 – 1.07 0.603 1401 13832 all phecode
696.3 Pityriasis Dermatologic 0.889 0.717 – 1.1 0.28 92 904 all phecode
696.4 Psoriasis Dermatologic 1.03 0.975 – 1.1 0.272 1311 12976 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.03 0.97 – 1.1 0.33 1200 11867 all phecode
696.42 Psoriatic arthropathy Dermatologic 0.967 0.853 – 1.1 0.599 282 2810 all phecode
697 Sarcoidosis Dermatologic 1.04 0.928 – 1.16 0.513 333 3330 all phecode
698 Pruritus and related conditions Dermatologic 0.995 0.952 – 1.04 0.832 2254 21889 all phecode
700 Corns and callosities Dermatologic 1.06 0.999 – 1.12 0.0552 1373 10894 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.992 0.967 – 1.02 0.525 7651 38050 all phecode
701.1 Keratoderma, acquired Dermatologic 1.03 0.946 – 1.13 0.467 567 5524 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.924 0.883 – 0.967 0.000636 2184 21550 all phecode
701.3 Circumscribed scleroderma Dermatologic 0.94 0.859 – 1.03 0.172 571 5660 all phecode
701.4 Keloid scar Dermatologic 0.927 0.849 – 1.01 0.0925 578 5716 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.09 0.986 – 1.21 0.0919 400 3982 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.875 0.851 – 0.9 4.89e-21 6956 29525 all phecode
702.1 Actinic keratosis Dermatologic 0.847 0.818 – 0.877 3.25e-21 4171 26529 all phecode
702.2 Seborrheic keratosis Dermatologic 0.871 0.846 – 0.898 4.52e-19 5480 31552 all phecode
702.4 Degenerative skin disorders Dermatologic 1.11 0.895 – 1.38 0.338 86 832 all phecode
703 Diseases of nail, NOS Dermatologic 1.01 0.958 – 1.06 0.721 1650 14562 all phecode
703.1 Ingrowing nail Dermatologic 1.05 0.976 – 1.12 0.208 920 8597 all phecode
704 Diseases of hair and hair follicles Dermatologic 0.941 0.906 – 0.978 0.00175 3118 29542 all phecode
704.1 Alopecia Dermatologic 0.904 0.854 – 0.957 0.000483 1408 13871 all phecode
704.11 Alopecia Areata Dermatologic 0.868 0.691 – 1.09 0.226 82 811 all phecode
704.12 Telogen effluvium Dermatologic 0.874 0.667 – 1.15 0.33 63 615 all phecode
704.2 Hirsutism Dermatologic 1.31 1.16 – 1.48 1.16e-05 299 2946 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.951 0.904 – 1 0.0508 1752 17189 all phecode
705 Disorders of sweat glands Dermatologic 1.18 1.08 – 1.28 0.000247 603 6012 all phecode
705.1 Dyshidrosis Dermatologic 1.01 0.849 – 1.2 0.901 154 1540 all phecode
705.3 Hidradenitis Dermatologic 1.41 1.23 – 1.62 7.11e-07 245 2440 all phecode
705.8 Hyperhidrosis Dermatologic 1.02 0.955 – 1.08 0.587 1112 10986 all phecode
706 Diseases of sebaceous glands Dermatologic 0.915 0.89 – 0.941 5.1e-10 5995 39748 all phecode
706.1 Acne Dermatologic 0.856 0.821 – 0.892 2.28e-13 2594 22570 all phecode
706.2 Sebaceous cyst Dermatologic 0.929 0.893 – 0.967 0.000315 2814 26819 all phecode
706.3 Seborrhea Dermatologic 0.845 0.645 – 1.11 0.219 59 582 all phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.959 0.91 – 1.01 0.114 1684 15289 all phecode
707 Chronic ulcer of skin Dermatologic 1.18 1.13 – 1.23 2.83e-16 2871 26816 all phecode
707.1 Decubitus ulcer Dermatologic 1.16 1.08 – 1.25 7.93e-05 825 8119 all phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.28 1.2 – 1.36 5.39e-14 1108 9992 all phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1.16 1.1 – 1.22 3.33e-08 1641 16172 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.981 0.928 – 1.04 0.49 1477 14427 all phecode
709.2 Sicca syndrome Dermatologic 0.997 0.908 – 1.1 0.957 505 4986 all phecode
709.3 Systemic sclerosis Dermatologic 0.852 0.744 – 0.976 0.0209 224 2209 all phecode
709.5 Dermatomyositis Dermatologic 1.13 0.919 – 1.4 0.243 92 892 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.05 0.835 – 1.31 0.696 90 892 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1 0.934 – 1.07 0.974 917 9089 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.2 1.13 – 1.27 2.47e-09 1254 12103 all phecode
710.1 Osteomyelitis Musculoskeletal 1.21 1.14 – 1.29 1.32e-09 1203 11636 all phecode
710.11 Acute osteomyelitis Musculoskeletal 1.36 1.25 – 1.49 4.38e-12 590 5708 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.23 1.12 – 1.35 1.4e-05 531 5163 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.21 1.14 – 1.29 1.17e-09 1153 11149 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.03 0.928 – 1.15 0.571 410 4099 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.15 1.02 – 1.3 0.0267 290 2900 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.28 1.09 – 1.51 0.00279 178 1776 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.16 1.03 – 1.31 0.0126 314 3028 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.23 1.06 – 1.44 0.00814 194 1824 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.11 1.06 – 1.17 1.05e-05 2086 18159 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.15 1.09 – 1.21 1.59e-07 1670 15087 all phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.02 0.812 – 1.29 0.848 77 767 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.13 1.06 – 1.2 0.000159 1209 11967 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.21 1.06 – 1.38 0.00453 262 2611 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.18 1.03 – 1.36 0.0211 219 2182 all phecode
716 Other arthropathies Musculoskeletal 1.12 1.1 – 1.15 1.19e-25 13482 31305 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.04 0.891 – 1.21 0.625 192 1920 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.933 0.776 – 1.12 0.466 131 1293 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.12 1.1 – 1.15 1.14e-25 13410 31294 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.933 0.817 – 1.06 0.302 261 2565 all phecode
720 Spinal stenosis Musculoskeletal 1.09 1.06 – 1.13 4.07e-07 3958 28539 all phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1.11 1.06 – 1.15 6.24e-07 2872 23656 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1.05 1.02 – 1.08 0.00213 5509 32391 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.04 1.01 – 1.07 0.016 5153 31896 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.07 0.996 – 1.15 0.0655 867 8629 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.2 1.06 – 1.37 0.00514 262 2600 all phecode
722 Intervertebral disc disorders Musculoskeletal 1.08 1.05 – 1.11 3.01e-08 6284 34317 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.07 1.03 – 1.1 0.000497 3591 31411 all phecode
722.3 Schmorl's nodes Musculoskeletal 1.11 0.911 – 1.35 0.3 126 1248 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.07 1.04 – 1.11 6.02e-05 3957 30744 all phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.06 0.967 – 1.17 0.208 515 5140 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.07 0.963 – 1.19 0.21 397 3968 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.03 0.984 – 1.08 0.192 1932 19288 all phecode
723 Other disorders of cervical region Musculoskeletal 0.996 0.93 – 1.07 0.906 952 9495 all phecode
723.1 Torticollis Musculoskeletal 0.999 0.876 – 1.14 0.986 254 2522 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.06 1.03 – 1.1 0.000383 4130 31954 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.07 1.03 – 1.12 0.00143 2307 21902 all phecode
724.2 Disorders of coccyx Musculoskeletal 1.07 0.966 – 1.19 0.189 426 4215 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.08 1.01 – 1.16 0.0282 931 9295 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.06 0.998 – 1.12 0.0575 1412 14087 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.979 0.956 – 1 0.0752 9917 30176 all phecode
726.1 Enthesopathy Musculoskeletal 0.973 0.947 – 0.998 0.038 7507 30106 all phecode
726.2 Synoviopathy Musculoskeletal 0.976 0.914 – 1.04 0.479 1015 9987 all phecode
726.3 Bursitis Musculoskeletal 0.947 0.901 – 0.996 0.033 1829 16722 all phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 1 0.942 – 1.06 0.964 1193 11485 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.986 0.96 – 1.01 0.294 7425 30105 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.995 0.957 – 1.03 0.803 3092 24998 all phecode
727.2 Bursitis disorders Musculoskeletal 0.98 0.883 – 1.09 0.7 419 4112 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.945 0.893 – 1 0.0525 1400 13621 all phecode
727.5 Rupture of synovium Musculoskeletal 1.08 0.983 – 1.19 0.108 480 4672 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.98 0.938 – 1.02 0.348 2461 21948 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.985 0.904 – 1.07 0.729 591 5893 all phecode
727.8 Plica syndrome Musculoskeletal 0.915 0.765 – 1.1 0.334 130 1264 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.02 0.988 – 1.05 0.222 4546 29473 all phecode
728.1 Muscular calcification and ossification Musculoskeletal 0.925 0.744 – 1.15 0.482 85 843 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.944 0.836 – 1.07 0.356 297 2949 all phecode
728.7 Fasciitis Musculoskeletal 0.969 0.931 – 1.01 0.13 2814 23463 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.811 0.731 – 0.899 7.22e-05 419 4138 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.11 1.07 – 1.15 7.32e-09 3642 27471 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1 0.784 – 1.28 0.976 74 726 all phecode
729.3 Panniculitis Musculoskeletal 1.38 1.14 – 1.67 0.00113 119 1174 all phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 1 0.778 – 1.29 1 67 664 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.23 1.07 – 1.42 0.00449 210 2091 all phecode
732 Osteochondropathies Musculoskeletal 1.12 1.01 – 1.26 0.0395 361 3604 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.22 1.05 – 1.42 0.00851 198 1969 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.05 0.839 – 1.31 0.686 90 882 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.909 0.879 – 0.94 1.79e-08 4543 26941 all phecode
733.2 Cyst of bone Musculoskeletal 0.923 0.794 – 1.07 0.297 190 1900 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.98 0.893 – 1.08 0.668 518 5160 all phecode
733.6 Costochondritis Musculoskeletal 0.921 0.825 – 1.03 0.145 357 3562 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.07 0.997 – 1.15 0.0595 822 8205 all phecode
733.9 Chondromalacia Musculoskeletal 0.954 0.774 – 1.18 0.664 96 960 all phecode
735 Acquired foot deformities Musculoskeletal 0.953 0.919 – 0.989 0.01 3417 29622 all phecode
735.1 Flat foot Musculoskeletal 0.959 0.881 – 1.04 0.328 620 6092 all phecode
735.2 Acquired toe deformities Musculoskeletal 0.965 0.909 – 1.02 0.235 1323 11983 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.986 0.914 – 1.06 0.709 825 7494 all phecode
735.23 Hallux rigidus Musculoskeletal 0.948 0.853 – 1.05 0.316 405 4005 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.903 0.855 – 0.954 0.000263 1470 14295 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.965 0.928 – 1 0.0859 2763 26555 all phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.842 0.686 – 1.03 0.101 104 1033 all phecode
736.2 Acquired deformities of finger Musculoskeletal 0.854 0.738 – 0.989 0.0353 215 2142 all phecode
736.3 Acquired deformities of hip Musculoskeletal 1.03 0.784 – 1.35 0.837 60 590 all phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.984 0.877 – 1.1 0.784 325 3247 all phecode
736.5 Acquired deformities of knee Musculoskeletal 0.948 0.833 – 1.08 0.416 246 2460 all phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.999 0.894 – 1.12 0.993 339 3365 all phecode
737 Curvature of spine Musculoskeletal 0.941 0.892 – 0.993 0.0259 1566 15543 all phecode
737.1 Kyphosis (acquired) Musculoskeletal 0.996 0.904 – 1.1 0.933 479 4748 all phecode
737.2 Lordosis (acquired) Musculoskeletal 1.32 1.02 – 1.7 0.0315 70 700 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.922 0.868 – 0.981 0.00968 1203 11982 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.01 0.968 – 1.05 0.626 2443 24187 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.1 1.03 – 1.18 0.00337 1057 10542 all phecode
739 Contracture of joint Musculoskeletal 0.985 0.906 – 1.07 0.732 621 6207 all phecode
740 Osteoarthrosis Musculoskeletal 1.14 1.11 – 1.16 1.53e-33 16169 30268 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.1 1.07 – 1.13 5.85e-12 7005 27422 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.09 1.06 – 1.12 1.26e-08 6176 26155 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.19 1.1 – 1.29 2.55e-05 713 7116 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.05 0.991 – 1.11 0.1 1609 12092 all phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 1.14 1.02 – 1.27 0.0224 373 3586 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.14 1.12 – 1.17 1.13e-34 15497 30141 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.01 0.983 – 1.03 0.555 8555 35884 all phecode
741.1 Ankylosis of joint Musculoskeletal 0.899 0.786 – 1.03 0.124 245 2445 all phecode
741.2 Stiffness of joint Musculoskeletal 0.914 0.861 – 0.97 0.00316 1268 12594 all phecode
741.3 Difficulty in walking Musculoskeletal 1.07 1.03 – 1.12 0.0011 2558 23116 all phecode
741.4 Joint effusions Musculoskeletal 0.995 0.953 – 1.04 0.809 2493 24199 all phecode
741.5 Hemarthrosis Musculoskeletal 1.05 0.841 – 1.3 0.689 94 937 all phecode
741.6 Villonodular synovitis Musculoskeletal 0.86 0.663 – 1.12 0.257 68 666 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.01 0.979 – 1.04 0.509 4404 33771 all phecode
742.1 Loose body in joint Musculoskeletal 1.27 1.08 – 1.5 0.00463 156 1554 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.92 0.813 – 1.04 0.183 280 2792 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.03 0.9 – 1.18 0.671 245 2450 all phecode
742.9 Other derangement of joint Musculoskeletal 1.01 0.978 – 1.05 0.501 4107 32972 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.926 0.903 – 0.949 8.02e-10 9223 36921 all phecode
743.1 Osteoporosis Musculoskeletal 0.897 0.863 – 0.931 1.69e-08 3712 19477 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.894 0.861 – 0.929 8.52e-09 3657 19276 all phecode
743.12 Senile osteoporosis Musculoskeletal 0.804 0.74 – 0.874 2.45e-07 703 5804 all phecode
743.13 Other specified osteoporosis Musculoskeletal 0.907 0.804 – 1.02 0.113 321 3141 all phecode
743.2 Pathologic fracture Musculoskeletal 0.946 0.887 – 1.01 0.0856 1112 10563 all phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 0.957 0.868 – 1.06 0.381 475 4629 all phecode
743.22 Pathologic fracture of femur Musculoskeletal 0.99 0.829 – 1.18 0.915 143 1391 all phecode
743.4 Stress fracture Musculoskeletal 0.94 0.847 – 1.04 0.252 407 4046 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.917 0.893 – 0.943 5.8e-10 6970 35237 all phecode
745 Pain in joint Musculoskeletal 0.99 0.972 – 1.01 0.303 19848 26918 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.02 0.977 – 1.07 0.345 2236 22256 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.06 1.01 – 1.11 0.0307 1767 17598 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.96 0.884 – 1.04 0.326 650 6497 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.07 0.988 – 1.16 0.0955 751 7480 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.14 1.03 – 1.26 0.0152 410 4090 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.921 0.84 – 1.01 0.0847 501 5010 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1 0.824 – 1.21 1 111 1110 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.914 0.837 – 0.999 0.0478 555 5549 all phecode
749.1 Cleft palate Congenital Anomalies 0.9 0.729 – 1.11 0.325 97 970 all phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 1.02 0.835 – 1.25 0.833 105 1041 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.947 0.882 – 1.02 0.127 893 8919 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.928 0.832 – 1.04 0.183 366 3655 all phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.896 0.74 – 1.08 0.259 119 1185 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.918 0.742 – 1.14 0.431 99 982 all phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 0.885 0.738 – 1.06 0.19 134 1332 all phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 1.12 0.854 – 1.47 0.41 60 593 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.937 0.855 – 1.03 0.16 531 5300 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.859 0.763 – 0.966 0.0115 313 3129 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.06 0.924 – 1.22 0.392 222 2214 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.985 0.94 – 1.03 0.516 2008 19975 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.986 0.904 – 1.08 0.751 574 5740 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.01 0.909 – 1.13 0.831 384 3840 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.949 0.806 – 1.12 0.527 153 1527 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.983 0.929 – 1.04 0.555 1379 13704 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.947 0.885 – 1.01 0.112 976 9685 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1 0.89 – 1.13 0.967 294 2927 all phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.1 0.943 – 1.28 0.233 182 1809 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.11 1.04 – 1.18 0.00125 1133 11313 all phecode
752.1 Neural tube defects Congenital Anomalies 1.14 1.07 – 1.23 0.000135 923 9209 all phecode
752.11 Spina bifida Congenital Anomalies 1.13 0.973 – 1.32 0.108 176 1760 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.994 0.869 – 1.14 0.924 232 2320 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.05 0.901 – 1.21 0.559 207 2051 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.908 0.694 – 1.19 0.482 58 580 all phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 1 0.757 – 1.33 0.974 56 546 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.09 1.03 – 1.16 0.00401 1216 12116 all phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 1.06 0.883 – 1.27 0.547 135 1333 all phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 1.08 0.984 – 1.18 0.107 558 5570 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.99 0.916 – 1.07 0.794 747 7458 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.977 0.877 – 1.09 0.665 368 3663 all phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 0.993 0.779 – 1.26 0.951 74 740 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.99 0.879 – 1.12 0.869 321 3205 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.07 0.909 – 1.25 0.435 185 1847 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.962 0.909 – 1.02 0.189 1358 13579 all phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.911 0.711 – 1.17 0.461 68 680 all phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 0.916 0.72 – 1.16 0.473 71 694 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.91 0.812 – 1.02 0.107 335 3346 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.984 0.921 – 1.05 0.622 1003 10014 all phecode
757 Congenital anomalies of the integument Congenital Anomalies 0.874 0.788 – 0.97 0.0114 401 4001 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.913 0.784 – 1.06 0.241 185 1845 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.882 0.737 – 1.05 0.169 135 1349 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.02 0.932 – 1.11 0.68 557 5566 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.933 0.726 – 1.2 0.589 71 710 all phecode
760 Back pain Symptoms 1.06 1.04 – 1.08 4.94e-09 16037 30719 all phecode
761 Cervicalgia Symptoms 0.995 0.968 – 1.02 0.693 6528 39755 all phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 1.04 1.01 – 1.08 0.0171 3657 32599 all phecode
764 Sciatica Symptoms 1.08 1.04 – 1.12 2.22e-05 3542 32015 all phecode
765 Cervical radiculitis Symptoms 0.986 0.938 – 1.04 0.578 1799 17851 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.05 1.02 – 1.09 0.000656 5124 37132 all phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 0.967 0.796 – 1.18 0.737 117 1168 all phecode
769 Nonallopathic lesions NEC Symptoms 0.964 0.905 – 1.03 0.255 1131 11220 all phecode
770 Myalgia and myositis unspecified Symptoms 1.05 1.02 – 1.08 0.00295 5533 34303 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.05 1.02 – 1.08 0.00235 4799 35575 all phecode
771.1 Swelling of limb Symptoms 1.13 1.1 – 1.16 9.75e-17 5743 35539 all phecode
771.2 Cramp of limb Symptoms 1.09 1.02 – 1.16 0.0103 1079 10568 all phecode
772 Symptoms of the muscles Symptoms 0.91 0.868 – 0.953 7.35e-05 2042 20221 all phecode
772.1 Muscular wasting and disuse atrophy Symptoms 0.99 0.894 – 1.1 0.847 422 4199 all phecode
772.2 Spasm of muscle Symptoms 1.01 0.967 – 1.06 0.65 2299 22726 all phecode
772.3 Muscle weakness Symptoms 1.04 1 – 1.08 0.048 2949 28064 all phecode
772.4 Rhabdomyolysis Symptoms 1.12 0.947 – 1.33 0.184 159 1572 all phecode
772.6 Facial weakness Symptoms 0.989 0.897 – 1.09 0.828 478 4742 all phecode
780 Hypothermia/Chills Symptoms 0.98 0.888 – 1.08 0.687 453 4514 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.02 0.978 – 1.06 0.387 2822 26225 all phecode
781.1 Loss of height Symptoms 0.996 0.823 – 1.21 0.965 130 1269 all phecode
781.2 Abnormal posture Symptoms 0.929 0.712 – 1.21 0.589 57 567 all phecode
782.3 Edema Symptoms 1.17 1.14 – 1.21 2.03e-27 5874 36788 all phecode
782.6 Pallor and flushing Symptoms 0.936 0.873 – 1 0.0623 927 9252 all phecode
783 Fever of unknown origin Symptoms 1.07 1.04 – 1.1 8.57e-06 5733 40720 all phecode
783.1 Postprocedural fever Symptoms 1.13 0.998 – 1.27 0.054 300 2992 all phecode
785 Abdominal pain Symptoms 1.04 1.02 – 1.06 2.97e-05 16458 30297 all phecode
788 Syncope and collapse Symptoms 1.02 0.99 – 1.06 0.162 3851 35832 all phecode
789 Nausea and vomiting Symptoms 1.05 1.03 – 1.07 2.2e-05 10568 36098 all phecode
789.1 Persistent vomiting Symptoms 1.14 1.06 – 1.23 0.000562 798 7924 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.08 1.03 – 1.13 0.000511 2363 22690 all phecode
790.1 Elevated sedimentation rate Symptoms 1.08 0.939 – 1.24 0.288 236 2322 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.07 1.04 – 1.1 1.96e-07 7539 37788 all phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.26 1.12 – 1.42 0.000169 309 3075 all phecode
790.9 Abnormal arterial blood gases Symptoms 1.23 1.04 – 1.46 0.0157 155 1521 all phecode
791 Gangrene Symptoms 1.21 1.07 – 1.36 0.00169 313 3115 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 0.968 0.929 – 1.01 0.128 2820 14872 all phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 0.982 0.921 – 1.05 0.58 1100 9861 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.965 0.88 – 1.06 0.45 515 5133 all phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 0.985 0.942 – 1.03 0.515 2182 20242 all phecode
795.8 Abnormal tumor markers Symptoms 0.919 0.874 – 0.967 0.00122 1745 15551 all phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 1.13 0.868 – 1.48 0.362 61 605 all phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 0.948 0.817 – 1.1 0.478 201 2000 all phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.869 0.827 – 0.913 2.46e-08 2125 9930 all phecode
797 Shock Symptoms 1.08 0.99 – 1.18 0.0839 605 6050 all phecode
797.1 Cardiogenic shock Symptoms 1.19 1.04 – 1.36 0.0115 242 2420 all phecode
798 Malaise and fatigue Symptoms 1 0.983 – 1.03 0.656 11539 35196 all phecode
798.1 Chronic fatigue syndrome Symptoms 0.998 0.95 – 1.05 0.938 1823 17795 all phecode
800 Fracture of lower limb Injuries & Poisonings 0.956 0.915 – 0.999 0.0426 2344 22951 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.979 0.891 – 1.08 0.662 512 4961 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.951 0.876 – 1.03 0.223 670 6582 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.974 0.908 – 1.04 0.456 898 8966 all phecode
800.4 Fracture of patella Injuries & Poisonings 0.913 0.816 – 1.02 0.107 346 3456 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.999 0.956 – 1.04 0.96 2358 22645 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.02 0.961 – 1.09 0.475 1120 11178 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.971 0.87 – 1.08 0.59 380 3765 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.932 0.89 – 0.976 0.00289 2051 20360 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.06 0.984 – 1.15 0.121 734 7322 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.893 0.839 – 0.951 0.00043 1112 11075 all phecode
803.21 Colles' fracture Injuries & Poisonings 0.85 0.753 – 0.96 0.0089 291 2904 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.857 0.781 – 0.94 0.00108 514 5140 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.902 0.856 – 0.95 9.39e-05 1628 16042 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1 0.946 – 1.06 0.938 1336 13242 all phecode
807 Fracture of ribs Injuries & Poisonings 0.975 0.901 – 1.06 0.534 683 6815 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.954 0.917 – 0.991 0.0164 2941 28633 all phecode
816 Cerebral laceration and contusion Injuries & Poisonings 1.16 0.871 – 1.53 0.316 54 531 all phecode
817 Concussion Injuries & Poisonings 0.994 0.931 – 1.06 0.847 1018 10149 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.85 0.755 – 0.956 0.00671 311 3104 all phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.881 0.711 – 1.09 0.251 90 895 all phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 0.989 0.798 – 1.22 0.916 97 970 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.958 0.917 – 1 0.0554 2287 22671 all phecode
830 Dislocation Injuries & Poisonings 0.957 0.925 – 0.991 0.0123 3862 34720 all phecode
835 Internal derangement of knee Injuries & Poisonings 0.99 0.947 – 1.03 0.651 2231 21628 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.1 0.997 – 1.21 0.0565 496 4954 all phecode
840 Sprains and strains Injuries & Poisonings 0.969 0.945 – 0.994 0.0136 7838 37998 all phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.981 0.895 – 1.07 0.68 537 5356 all phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 1.02 0.969 – 1.08 0.426 1640 16263 all phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.926 0.89 – 0.963 0.000129 2875 24879 all phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.976 0.925 – 1.03 0.361 1583 15592 all phecode
842 Other sprains and strains Injuries & Poisonings 0.949 0.897 – 1 0.0646 1407 13924 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.09 1.04 – 1.14 0.000267 2072 20649 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.15 1.1 – 1.19 5.74e-12 2982 27545 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.08 0.983 – 1.19 0.106 460 4600 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.14 1.09 – 1.2 2.59e-08 1985 19675 all phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.09 0.96 – 1.24 0.183 264 2640 all phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.07 0.943 – 1.21 0.305 293 2929 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.09 1.02 – 1.15 0.00585 1310 13087 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.07 1.03 – 1.12 0.00192 2213 21944 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.08 1.03 – 1.13 0.000705 2110 21070 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1.05 0.898 – 1.24 0.518 166 1660 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.03 1 – 1.07 0.0531 4117 36734 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.02 0.878 – 1.18 0.798 204 2026 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.919 0.774 – 1.09 0.334 144 1437 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.876 0.828 – 0.928 6.59e-06 1346 13301 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.924 0.799 – 1.07 0.285 207 2057 all phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 0.929 0.817 – 1.06 0.259 275 2724 all phecode
870.6 Open wound of neck Injuries & Poisonings 1 0.867 – 1.16 0.971 214 2128 all phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.15 0.971 – 1.36 0.105 144 1440 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.04 0.999 – 1.07 0.0541 3530 32903 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1 0.915 – 1.09 0.992 572 5701 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.928 0.868 – 0.992 0.0291 984 9772 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.23 1.12 – 1.36 1.35e-05 490 4843 all phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.1 0.972 – 1.24 0.13 295 2921 all phecode
872 Traumatic amputation Injuries & Poisonings 1.16 1.06 – 1.26 0.00144 551 5477 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.28 1.09 – 1.5 0.0022 170 1697 all phecode
875 Non-healing surgical wound Injuries & Poisonings 1.21 1.11 – 1.32 1.94e-05 572 5720 all phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.28 1.19 – 1.38 1.26e-10 802 8003 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.01 0.943 – 1.08 0.833 1010 10096 all phecode
910 Superficial injury, infected Injuries & Poisonings 0.944 0.78 – 1.14 0.555 119 1161 all phecode
911 Blister Injuries & Poisonings 1.14 1.01 – 1.29 0.0292 302 2996 all phecode
912 Insect bite Injuries & Poisonings 0.968 0.88 – 1.06 0.506 492 4886 all phecode
913 Toxic effect of venom Injuries & Poisonings 0.784 0.697 – 0.882 4.96e-05 337 3326 all phecode
916 Contusion Injuries & Poisonings 1.03 0.993 – 1.06 0.131 4296 38033 all phecode
930 Allergic reaction to food Injuries & Poisonings 1 0.929 – 1.08 0.937 763 7596 all phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.926 0.856 – 1 0.0556 714 7072 all phecode
938 Dermatitis due to solar radiation Dermatologic 0.881 0.855 – 0.908 1.7e-16 5567 29098 all phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 1.02 0.885 – 1.17 0.786 217 2164 all phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.873 0.847 – 0.9 6e-18 5307 28656 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.965 0.938 – 0.991 0.00968 6704 32389 all phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 1.04 0.831 – 1.31 0.715 91 870 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.15 0.986 – 1.33 0.0748 188 1880 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.03 0.904 – 1.18 0.646 269 2688 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.973 0.885 – 1.07 0.571 500 4940 all phecode
947 Urticaria Dermatologic 0.98 0.922 – 1.04 0.521 1177 11454 all phecode
949 Allergies, other Injuries & Poisonings 1.01 0.979 – 1.03 0.702 7251 32350 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.03 0.941 – 1.14 0.488 494 4940 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.891 0.747 – 1.06 0.201 136 1352 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.09 1.03 – 1.16 0.0035 1217 12158 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.04 0.885 – 1.23 0.619 169 1688 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.965 0.79 – 1.18 0.726 114 1140 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.14 1.09 – 1.19 1.22e-09 2479 22087 all phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 1.05 0.933 – 1.18 0.434 342 3403 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.17 1.11 – 1.23 8.87e-09 1636 16005 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.13 1.03 – 1.23 0.0106 528 5234 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.12 1.05 – 1.19 0.000862 1065 10347 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.07 0.989 – 1.15 0.0938 803 7976 all phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.94 – 1.17 0.401 379 3782 all phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 1.18 0.906 – 1.53 0.223 62 612 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.07 0.971 – 1.18 0.171 478 4773 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1 0.96 – 1.04 0.962 2533 24531 all phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.01 0.967 – 1.05 0.681 2469 24057 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.12 1.04 – 1.21 0.00348 743 7337 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.13 1.04 – 1.22 0.00291 712 7027 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.06 0.988 – 1.14 0.104 864 8601 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.14 1.08 – 1.21 1.61e-06 1469 14402 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.922 0.766 – 1.11 0.392 119 1182 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.976 0.797 – 1.2 0.813 103 1006 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.996 0.938 – 1.06 0.892 1254 12464 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.12 0.99 – 1.27 0.0714 281 2797 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.1 0.852 – 1.43 0.455 67 643 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.17 1.04 – 1.33 0.0109 288 2858 all phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 1.17 0.921 – 1.48 0.2 80 776 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.25 1.02 – 1.52 0.0288 104 1034 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.16 0.954 – 1.4 0.139 113 1130 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.04 0.825 – 1.32 0.728 81 810 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.13 0.876 – 1.45 0.356 71 703 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.11 1.05 – 1.17 5.67e-05 1763 16599 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.04 1.01 – 1.08 0.021 3448 30885 all phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 1.02 0.966 – 1.08 0.448 1391 13877 all phecode
985 Toxic effect of other metals Injuries & Poisonings 1.14 0.868 – 1.5 0.345 57 564 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.02 0.85 – 1.22 0.837 129 1275 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.01 0.98 – 1.05 0.418 3927 31223 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.14 1.09 – 1.19 1.02e-08 2192 21710 all phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.2 1.06 – 1.36 0.00462 291 2910 all phecode
994.2 Sepsis Injuries & Poisonings 1.14 1.09 – 1.2 1.99e-08 2086 20666 all phecode
994.21 Septic shock Injuries & Poisonings 1.19 1.09 – 1.29 8.14e-05 627 6260 all phecode
008 Intestinal infection Infectious Diseases 1.02 0.945 – 1.1 0.595 745 6950 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.19 1.06 – 1.34 0.00347 321 2987 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.2 1.05 – 1.37 0.0069 251 2331 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.07 0.909 – 1.26 0.425 168 1792 exclusion phecode
010 Tuberculosis Infectious Diseases 1.13 0.875 – 1.47 0.344 61 539 exclusion phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.966 0.652 – 1.43 0.863 27 197 exclusion phecode
038 Septicemia Infectious Diseases 1.26 1.15 – 1.37 7.33e-07 551 5136 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.16 0.956 – 1.4 0.136 115 1172 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.52 1.13 – 2.03 0.00498 50 455 exclusion phecode
038.3 Bacteremia Infectious Diseases 1.2 1.06 – 1.37 0.00441 266 2396 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.15 1.08 – 1.21 6.15e-06 1319 9006 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.37 1.23 – 1.54 1.63e-08 349 3617 exclusion phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.38 1.19 – 1.61 3.44e-05 181 1916 exclusion phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.35 1.14 – 1.58 0.000395 157 1700 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.24 1.11 – 1.38 8.3e-05 381 3462 exclusion phecode
041.21 Rheumatic fever / chorea Infectious Diseases 1.11 0.825 – 1.51 0.48 50 554 exclusion phecode
041.4 E. coli Infectious Diseases 1.27 1.11 – 1.45 0.000448 260 2614 exclusion phecode
041.8 H. pylori Infectious Diseases 0.952 0.723 – 1.25 0.724 58 595 exclusion phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.43 1.14 – 1.8 0.00171 96 849 exclusion phecode
053 Herpes zoster Infectious Diseases 0.914 0.818 – 1.02 0.11 369 3324 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.951 0.712 – 1.27 0.73 50 459 exclusion phecode
054 Herpes simplex Infectious Diseases 0.934 0.842 – 1.04 0.196 422 3794 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.14 0.975 – 1.34 0.0996 193 1614 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.68 0.927 – 3.06 0.0871 11 160 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.891 0.666 – 1.19 0.436 52 441 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.27 1.05 – 1.54 0.0154 129 966 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.04 0.757 – 1.42 0.821 53 395 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.2 1.05 – 1.38 0.00792 245 2187 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.49 1.12 – 1.98 0.00658 59 289 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.5 1.1 – 2.05 0.0107 50 218 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.907 0.845 – 0.973 0.00676 911 7141 exclusion phecode
079 Viral infection Infectious Diseases 0.978 0.927 – 1.03 0.409 1707 8160 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.899 0.839 – 0.963 0.00247 975 7161 exclusion phecode
079.2 Infectious mononucleosis Infectious Diseases 0.864 0.702 – 1.06 0.168 106 885 exclusion phecode
079.9 Viremia, NOS Infectious Diseases 1.19 1.03 – 1.38 0.0162 214 2028 exclusion phecode
080 Postoperative infection Infectious Diseases 1.21 1.1 – 1.32 3.24e-05 540 5845 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.26 1.13 – 1.41 2.51e-05 389 3473 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.01 0.891 – 1.14 0.886 277 2444 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.95 0.875 – 1.03 0.221 644 6718 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.962 0.881 – 1.05 0.397 555 6022 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.932 0.832 – 1.05 0.23 340 3534 exclusion phecode
110.12 Althete's foot Infectious Diseases 1 0.835 – 1.2 0.988 129 1645 exclusion phecode
110.13 Dermatophytosis of the body Infectious Diseases 0.907 0.761 – 1.08 0.274 131 1711 exclusion phecode
110.2 Dermatomycoses Infectious Diseases 0.979 0.799 – 1.2 0.84 103 952 exclusion phecode
112 Candidiasis Infectious Diseases 1.13 1.05 – 1.21 0.000942 876 7564 exclusion phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.1 0.843 – 1.43 0.488 57 1616 exclusion phecode
117 Mycoses Infectious Diseases 1.16 0.981 – 1.37 0.0829 164 1439 exclusion phecode
117.1 Histoplasmosis Infectious Diseases 1.25 0.792 – 1.96 0.343 23 193 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.38 1.02 – 1.86 0.0375 49 340 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.837 0.628 – 1.12 0.224 48 434 exclusion phecode
130.1 Lyme disease Infectious Diseases 0.774 0.555 – 1.08 0.132 38 309 exclusion phecode
131 Protozoan infection Infectious Diseases 1.45 0.834 – 2.52 0.188 11 163 exclusion phecode
132 Infestation (lice, mites) Infectious Diseases 1.18 0.88 – 1.59 0.266 46 468 exclusion phecode
134 Helminthiases Infectious Diseases 1.13 0.714 – 1.79 0.599 22 177 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.33 0.764 – 2.33 0.312 16 108 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.12 1.04 – 1.2 0.00224 854 7457 exclusion phecode
145 Cancer of mouth Neoplasms 1.29 1.16 – 1.43 4.23e-06 402 2723 exclusion phecode
145.1 Cancer of lip Neoplasms 1.62 1 – 2.62 0.049 16 137 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.2 1.02 – 1.4 0.024 186 1121 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 1.03 0.816 – 1.3 0.809 79 717 exclusion phecode
145.4 Cancer of the gums Neoplasms 1.57 1.16 – 2.12 0.00373 54 343 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.54 1.19 – 2 0.00115 75 363 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.27 1.14 – 1.43 3.81e-05 355 2312 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.44 1.15 – 1.81 0.0014 105 568 exclusion phecode
149.2 Cancer of nasopharynx Neoplasms 1.42 0.958 – 2.11 0.0807 33 211 exclusion phecode
149.3 Cancer of hypopharynx Neoplasms 1.35 0.894 – 2.03 0.154 28 154 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.32 1.06 – 1.64 0.0127 102 636 exclusion phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 1.39 1.16 – 1.66 0.00036 148 971 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.12 0.832 – 1.49 0.464 60 466 exclusion phecode
150 Cancer of esophagus Neoplasms 1.43 1.16 – 1.75 0.000724 99 751 exclusion phecode
151 Cancer of stomach Neoplasms 1.11 0.899 – 1.36 0.342 112 884 exclusion phecode
153 Colorectal cancer Neoplasms 1.06 0.94 – 1.19 0.344 307 2977 exclusion phecode
153.2 Colon cancer Neoplasms 1.06 0.922 – 1.22 0.412 224 2327 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.01 0.865 – 1.17 0.939 194 1749 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.12 0.917 – 1.37 0.264 109 958 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.19 0.929 – 1.53 0.166 72 634 exclusion phecode
157 Pancreatic cancer Neoplasms 1.18 0.963 – 1.43 0.112 119 943 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.02 0.909 – 1.14 0.769 366 3192 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.11 0.997 – 1.24 0.0559 398 3485 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.904 0.655 – 1.25 0.541 44 428 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.21 0.881 – 1.66 0.239 44 300 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.17 0.918 – 1.49 0.206 74 624 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.85 0.602 – 1.2 0.358 36 255 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.17 1.04 – 1.32 0.00942 327 2562 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.13 0.992 – 1.29 0.0666 254 2026 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 1.12 1.01 – 1.24 0.0248 438 3720 exclusion phecode
170.1 Bone cancer Neoplasms 1.21 1.05 – 1.4 0.0102 205 1645 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1.11 0.98 – 1.25 0.102 295 2650 exclusion phecode
172 Skin cancer Neoplasms 0.953 0.904 – 1 0.0747 2005 7136 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.912 0.854 – 0.973 0.00547 1183 6208 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.92 0.846 – 1 0.0547 622 5040 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.952 0.899 – 1.01 0.09 1698 6245 exclusion phecode
172.21 Basal cell carcinoma Neoplasms 0.885 0.821 – 0.953 0.00121 900 4642 exclusion phecode
172.22 Squamous cell carcinoma Neoplasms 1.04 0.952 – 1.14 0.368 583 3196 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.885 0.789 – 0.993 0.0378 363 2293 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.917 0.831 – 1.01 0.0867 472 3913 exclusion phecode
174 Breast cancer Neoplasms 0.863 0.801 – 0.929 9.38e-05 942 4018 exclusion phecode
174.1 Breast cancer [female] Neoplasms 0.871 0.807 – 0.939 0.000327 905 3840 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.879 0.814 – 0.948 0.000854 886 3818 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.706 0.539 – 0.924 0.0111 65 592 exclusion phecode
175 Acquired absence of breast Neoplasms 0.84 0.742 – 0.951 0.00596 301 2272 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 0.993 0.898 – 1.1 0.895 442 3333 exclusion phecode
180.1 Cervical cancer Neoplasms 1.06 0.892 – 1.27 0.488 135 1295 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.946 0.845 – 1.06 0.337 356 2584 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.892 0.733 – 1.09 0.257 105 1877 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.01 0.892 – 1.14 0.913 313 2979 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.93 0.782 – 1.11 0.416 151 1504 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.959 0.788 – 1.17 0.676 120 1139 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.11 0.931 – 1.33 0.243 150 1531 exclusion phecode
185 Cancer of prostate Neoplasms 0.87 0.77 – 0.982 0.0241 399 1589 exclusion phecode
187 Cancer of other male genital organs Neoplasms 1 0.775 – 1.3 0.979 66 631 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.24 0.742 – 2.07 0.412 14 181 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.927 0.684 – 1.26 0.623 42 389 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.13 0.624 – 2.04 0.688 12 97 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.04 0.941 – 1.14 0.467 474 4570 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.08 0.933 – 1.24 0.314 217 2783 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.06 0.906 – 1.24 0.47 179 2436 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.2 0.861 – 1.68 0.278 43 421 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.03 0.914 – 1.17 0.599 307 2791 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.07 0.945 – 1.22 0.276 290 2565 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.21 0.992 – 1.47 0.0604 116 1178 exclusion phecode
190 Cancer of eye Neoplasms 1.09 0.776 – 1.54 0.613 44 274 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.09 0.96 – 1.24 0.179 257 2389 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.999 0.858 – 1.16 0.985 189 1564 exclusion phecode
191.11 Cancer of brain Neoplasms 1.04 0.886 – 1.22 0.629 166 1311 exclusion phecode
193 Thyroid cancer Neoplasms 1.14 0.978 – 1.33 0.0946 180 2295 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.17 0.968 – 1.42 0.103 115 1361 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.02 0.977 – 1.07 0.339 3803 6337 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.02 0.974 – 1.07 0.426 3739 6336 exclusion phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1.27 1.12 – 1.44 0.000281 276 1686 exclusion phecode
196 Radiotherapy Neoplasms 0.979 0.893 – 1.07 0.643 560 3437 exclusion phecode
197 Chemotherapy Neoplasms 1.1 1.03 – 1.17 0.00456 1227 5333 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.13 1.06 – 1.2 0.000306 1285 5236 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.09 1.01 – 1.18 0.0261 840 4617 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.28 1.11 – 1.48 0.000675 218 1968 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.06 0.918 – 1.22 0.426 220 1681 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.16 0.996 – 1.36 0.0561 193 1429 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.18 0.995 – 1.4 0.0569 154 1229 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.39 1.19 – 1.63 2.98e-05 188 1540 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.11 0.873 – 1.42 0.389 81 608 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.04 0.974 – 1.11 0.245 1222 6068 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.35 0.955 – 1.9 0.09 30 219 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.22 1.07 – 1.38 0.00317 259 2376 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.22 0.887 – 1.69 0.219 43 384 exclusion phecode
201 Hodgkin's disease Neoplasms 1.58 1.18 – 2.13 0.00246 47 409 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.16 1.04 – 1.3 0.00647 375 3286 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.15 1.02 – 1.29 0.0214 318 2810 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.12 0.957 – 1.32 0.157 183 1510 exclusion phecode
202.22 Reticulosarcoma Neoplasms 1.19 0.842 – 1.67 0.327 36 352 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.25 0.879 – 1.78 0.214 38 319 exclusion phecode
204 Leukemia Neoplasms 1.13 0.953 – 1.34 0.16 153 1343 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1.21 0.914 – 1.61 0.181 58 448 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.22 0.76 – 1.96 0.411 21 173 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.15 0.814 – 1.61 0.435 38 313 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.16 0.895 – 1.52 0.257 62 505 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 1.12 0.778 – 1.6 0.552 36 268 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.965 0.569 – 1.63 0.893 16 128 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.19 0.873 – 1.63 0.268 42 438 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1.01 0.958 – 1.06 0.773 2119 8346 exclusion phecode
209 Neuroendocrine tumors Neoplasms 1.04 0.758 – 1.43 0.809 41 515 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.992 0.902 – 1.09 0.877 499 4205 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.09 1.03 – 1.15 0.00169 1559 8697 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.19 1.08 – 1.32 0.000538 437 3952 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.08 0.971 – 1.19 0.163 415 3699 exclusion phecode
214 Lipoma Neoplasms 1.04 0.914 – 1.19 0.546 260 3192 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.997 0.844 – 1.18 0.972 160 2008 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.02 0.956 – 1.09 0.531 1012 9144 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.884 0.845 – 0.924 6.01e-08 2817 8094 exclusion phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 1.25 0.908 – 1.72 0.17 45 416 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.803 0.729 – 0.885 1.01e-05 502 3752 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.798 0.721 – 0.883 1.37e-05 464 3438 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.9 0.842 – 0.963 0.00212 1154 4797 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.839 0.759 – 0.927 0.000558 461 4411 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.898 0.835 – 0.965 0.0036 944 4715 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.884 0.767 – 1.02 0.0884 226 2392 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.924 0.84 – 1.02 0.104 506 4088 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.744 0.637 – 0.87 0.000215 182 1720 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.997 0.885 – 1.12 0.961 326 2723 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.91 0.766 – 1.08 0.288 161 1399 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.9 0.745 – 1.09 0.277 134 1127 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.2 1.06 – 1.35 0.00496 275 2764 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.13 0.984 – 1.31 0.083 213 2174 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.39 1.1 – 1.77 0.00684 71 639 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.967 0.85 – 1.1 0.617 259 3226 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.964 0.851 – 1.09 0.559 283 3878 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.12 0.868 – 1.44 0.388 63 965 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.941 0.797 – 1.11 0.468 157 1863 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.863 0.667 – 1.12 0.262 63 1012 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.801 0.73 – 0.88 3.24e-06 538 4535 exclusion phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.742 0.661 – 0.833 4.44e-07 355 2832 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.968 0.917 – 1.02 0.24 1669 8554 exclusion phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.964 0.906 – 1.03 0.245 1210 7778 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.06 0.925 – 1.23 0.381 219 2530 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.03 0.944 – 1.12 0.515 605 5567 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.997 0.904 – 1.1 0.947 475 4945 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.02 0.886 – 1.16 0.825 236 3181 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.02 0.907 – 1.15 0.725 299 3335 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.899 0.744 – 1.09 0.272 118 1249 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.08 0.67 – 1.73 0.763 19 307 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.895 0.702 – 1.14 0.369 72 698 exclusion phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.921 0.656 – 1.29 0.633 38 356 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.05 0.994 – 1.11 0.0827 1647 7677 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.99 0.887 – 1.11 0.861 351 4262 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.04 0.921 – 1.18 0.517 284 3037 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.05 0.99 – 1.11 0.104 1538 7562 exclusion phecode
245 Thyroiditis Endocrine/metabolic 1.19 1.02 – 1.4 0.0273 178 2110 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.24 1.04 – 1.48 0.017 138 1770 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.23 1.03 – 1.47 0.0239 137 1751 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.04 0.981 – 1.11 0.173 1301 7120 exclusion phecode
246.2 Thyroid cyst Endocrine/metabolic 0.956 0.64 – 1.43 0.827 25 228 exclusion phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1.03 0.897 – 1.19 0.653 218 2156 exclusion phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.26 1.04 – 1.52 0.0165 169 1894 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.1 1.04 – 1.16 0.00115 1798 8752 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.17 1.01 – 1.35 0.0365 469 2920 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.51 1.06 – 2.16 0.022 103 226 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.18 0.932 – 1.5 0.168 154 616 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.45 1.13 – 1.87 0.00373 189 705 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.4 1.1 – 1.79 0.00691 160 588 exclusion phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 1.21 0.843 – 1.74 0.3 49 173 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.16 1.07 – 1.25 0.000145 1078 7827 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.53 1.04 – 2.26 0.0316 77 288 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.46 1.22 – 1.75 3.66e-05 173 3130 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.17 0.963 – 1.41 0.115 207 2284 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.22 1.03 – 1.45 0.0237 215 3893 exclusion phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.14 0.881 – 1.46 0.327 71 1331 exclusion phecode
250.3 Insulin pump user Endocrine/metabolic 1.23 1.07 – 1.4 0.00255 438 5081 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.06 0.994 – 1.14 0.0753 1238 8248 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.934 0.806 – 1.08 0.362 232 4125 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.08 1 – 1.16 0.0426 1125 7996 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.77 1.08 – 2.89 0.0228 26 290 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.31 1.08 – 1.58 0.00574 205 3102 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.13 0.977 – 1.31 0.101 256 2093 exclusion phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.14 0.995 – 1.31 0.0596 245 1974 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.2 1.04 – 1.38 0.0126 310 2348 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.08 0.979 – 1.19 0.125 477 5165 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.06 0.954 – 1.17 0.295 435 4715 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.2 0.974 – 1.48 0.0874 98 1179 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.975 0.828 – 1.15 0.757 164 1895 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.07 0.79 – 1.45 0.666 48 670 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.819 0.465 – 1.44 0.49 11 203 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.731 0.521 – 1.03 0.0693 32 477 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.36 0.851 – 2.16 0.201 15 182 exclusion phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 0.743 0.44 – 1.25 0.266 18 220 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.11 0.764 – 1.62 0.575 30 242 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.19 1.05 – 1.34 0.00729 276 3379 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.03 0.786 – 1.34 0.841 56 924 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.754 0.508 – 1.12 0.16 26 495 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.32 0.832 – 2.11 0.236 15 281 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.19 0.99 – 1.42 0.0637 131 1432 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.2 0.997 – 1.45 0.0541 123 1361 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.897 0.783 – 1.03 0.119 237 3240 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.744 0.59 – 0.938 0.0123 78 2257 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 0.971 0.808 – 1.17 0.751 127 1530 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.971 0.805 – 1.17 0.754 122 1469 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.28 0.777 – 2.09 0.336 17 186 exclusion phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.903 0.624 – 1.31 0.586 31 330 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.958 0.827 – 1.11 0.564 201 2439 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.24 1.15 – 1.33 2.51e-09 988 5553 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.34 1.1 – 1.63 0.00343 147 559 exclusion phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.38 1.26 – 1.51 3.13e-12 600 3325 exclusion phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.46 1.25 – 1.7 1.35e-06 214 1201 exclusion phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.36 1.16 – 1.58 0.000107 210 1199 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.29 1.13 – 1.47 0.000206 264 1878 exclusion phecode
260.7 Polyphagia Endocrine/metabolic 0.736 0.439 – 1.23 0.246 16 167 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.11 1.05 – 1.18 0.000141 1599 8182 exclusion phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1.93 1.19 – 3.13 0.0075 22 160 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.3 1.11 – 1.53 0.00107 175 1833 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.11 1.05 – 1.17 0.000451 1500 8199 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.23 0.712 – 2.12 0.461 14 118 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.22 1.07 – 1.38 0.00242 269 2874 exclusion phecode
263 Other nutritional deficiency Endocrine/metabolic 1.13 1.01 – 1.26 0.0297 368 3637 exclusion phecode
264 Lack of normal physiological development Endocrine/metabolic 1.08 0.87 – 1.34 0.487 103 699 exclusion phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.17 0.866 – 1.58 0.307 51 309 exclusion phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 0.905 0.642 – 1.27 0.566 38 286 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.36 1.2 – 1.54 2.23e-06 286 3036 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.14 0.98 – 1.32 0.0916 201 2098 exclusion phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.846 0.591 – 1.21 0.364 34 418 exclusion phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.784 0.53 – 1.16 0.224 29 348 exclusion phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 1.22 0.71 – 2.1 0.471 10 223 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.22 1.03 – 1.44 0.0189 164 1518 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.08 0.845 – 1.39 0.527 72 737 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 0.818 0.499 – 1.34 0.426 19 142 exclusion phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 1.04 0.553 – 1.95 0.909 18 134 exclusion phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.43 1.11 – 1.83 0.00508 76 663 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.01 0.909 – 1.11 0.912 417 6296 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.994 0.895 – 1.1 0.907 394 6130 exclusion phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.32 0.866 – 2.02 0.195 26 230 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.04 0.993 – 1.09 0.0914 2862 7532 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.04 0.993 – 1.09 0.0953 2851 7518 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.02 0.941 – 1.1 0.69 885 5677 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.927 0.766 – 1.12 0.436 112 2933 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.997 0.896 – 1.11 0.957 426 4669 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.927 0.709 – 1.21 0.583 61 737 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.14 1.01 – 1.29 0.0411 266 4357 exclusion phecode
274.1 Gout Endocrine/metabolic 1.18 1.03 – 1.35 0.0182 232 4169 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.2 0.986 – 1.46 0.0683 106 2021 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.846 0.614 – 1.17 0.31 44 379 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.887 0.646 – 1.22 0.459 43 358 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.18 1.1 – 1.27 1.98e-06 945 8233 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.911 0.611 – 1.36 0.649 27 469 exclusion phecode
275.11 Hereditary hemochromatosis Hematopoietic 1.18 0.566 – 2.45 0.66 7 203 exclusion phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 1.68 0.937 – 3.02 0.0814 15 153 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.41 1.24 – 1.6 1.48e-07 273 2426 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.14 1.06 – 1.24 0.000607 738 7005 exclusion phecode
275.51 Hypocalcemia Endocrine/metabolic 1.33 1.15 – 1.54 9.15e-05 218 1971 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.21 1.08 – 1.37 0.00165 320 2783 exclusion phecode
275.6 Hypercalcemia Endocrine/metabolic 1.14 1.01 – 1.29 0.0338 290 3120 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.26 1.19 – 1.32 1.26e-18 2041 8801 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.31 1.23 – 1.39 1.71e-18 1364 7723 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.25 1.03 – 1.52 0.0223 127 1035 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.33 1.22 – 1.45 1.13e-10 637 4587 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.36 1.25 – 1.48 3.93e-12 600 5079 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.34 1.21 – 1.48 1e-08 444 4590 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.26 1.14 – 1.4 5.64e-06 443 4136 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.28 1.15 – 1.43 9.43e-06 371 3556 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.36 1.12 – 1.66 0.00197 124 982 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.25 1.17 – 1.33 1.78e-11 1141 7954 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.52 1.32 – 1.74 6.66e-09 239 2587 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 0.873 0.592 – 1.29 0.494 24 289 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.08 0.998 – 1.17 0.0562 701 8379 exclusion phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.33 0.929 – 1.92 0.118 28 771 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.983 0.834 – 1.16 0.835 161 1518 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.919 0.771 – 1.09 0.343 143 2051 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.917 0.752 – 1.12 0.394 109 1709 exclusion phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.31 0.862 – 1.99 0.206 17 1926 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.24 1.15 – 1.34 1.28e-07 678 10325 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.5 1.29 – 1.74 1.54e-07 177 10321 exclusion phecode
278.11 Morbid obesity Endocrine/metabolic 1.95 1.44 – 2.63 1.34e-05 40 10260 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 1.17 0.834 – 1.65 0.359 31 1298 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.14 1.02 – 1.29 0.024 307 7284 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.1 1.02 – 1.19 0.0114 806 6578 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.14 1.01 – 1.28 0.028 328 2565 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.07 0.849 – 1.34 0.584 93 720 exclusion phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 1 0.863 – 1.17 0.953 198 1809 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.02 0.956 – 1.09 0.552 1119 8305 exclusion phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 1.05 0.894 – 1.24 0.544 171 1473 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.16 1.09 – 1.24 6.15e-06 1078 7054 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.17 1.09 – 1.25 7.55e-06 1043 7020 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.18 1.07 – 1.31 0.00147 408 3775 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.16 0.953 – 1.42 0.136 116 1161 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.07 0.818 – 1.41 0.606 62 579 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.1 0.719 – 1.68 0.665 28 267 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.995 0.705 – 1.4 0.977 43 434 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.17 0.905 – 1.52 0.228 63 652 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.1 0.856 – 1.41 0.46 69 693 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.01 0.739 – 1.38 0.951 46 437 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.39 0.998 – 1.92 0.0511 38 411 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.27 0.894 – 1.8 0.184 33 345 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.847 0.5 – 1.43 0.538 15 152 exclusion phecode
284 Aplastic anemia Hematopoietic 1.29 1.1 – 1.5 0.00155 181 1365 exclusion phecode
284.1 Pancytopenia Hematopoietic 1.34 1.13 – 1.59 0.000787 157 1208 exclusion phecode
285 Other anemias Hematopoietic 1.17 1.12 – 1.23 2.69e-12 2829 7835 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.21 1.12 – 1.31 5.56e-07 806 5912 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.38 1.26 – 1.52 1.19e-11 523 4091 exclusion phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.42 1.24 – 1.64 7.09e-07 221 1743 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.28 1.09 – 1.5 0.00251 182 1437 exclusion phecode
286 Coagulation defects Hematopoietic 1.12 1.03 – 1.2 0.0049 767 7586 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.794 0.592 – 1.07 0.124 50 594 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.778 0.499 – 1.21 0.267 20 197 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.851 0.56 – 1.29 0.451 22 307 exclusion phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.1 1.01 – 1.2 0.0374 550 5391 exclusion phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 1.4 0.949 – 2.06 0.0897 34 325 exclusion phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 1.11 0.833 – 1.48 0.479 50 500 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.975 0.674 – 1.41 0.895 24 279 exclusion phecode
286.6 Defibrination syndrome Hematopoietic 1.09 0.995 – 1.2 0.0647 491 5592 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.09 1 – 1.19 0.0496 588 6545 exclusion phecode
286.8 Hypercoagulable state Hematopoietic 1.11 0.94 – 1.32 0.215 158 1963 exclusion phecode
286.81 Primary hypercoagulable state Hematopoietic 1.11 0.931 – 1.32 0.248 150 1863 exclusion phecode
286.9 Abnormal coagulation profile Hematopoietic 1.3 1.13 – 1.5 0.00018 224 2405 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.15 1.07 – 1.24 0.000379 740 6201 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.738 0.555 – 0.981 0.0366 55 491 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.18 1.09 – 1.28 7.18e-05 671 5659 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.17 0.969 – 1.41 0.102 119 1303 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.25 1.04 – 1.5 0.0182 135 1209 exclusion phecode
287.4 Qualitative platelet defects Hematopoietic 1.03 0.68 – 1.56 0.893 23 267 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.13 1.06 – 1.2 2e-04 1201 8361 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.11 1.01 – 1.22 0.0237 515 3506 exclusion phecode
288.11 Neutropenia Hematopoietic 1.2 1.07 – 1.35 0.00176 341 2383 exclusion phecode
288.2 Elevated white blood cell count Hematopoietic 1.11 1.04 – 1.19 0.00305 962 7794 exclusion phecode
288.3 Eosinophilia Hematopoietic 0.89 0.65 – 1.22 0.47 46 411 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.15 1.03 – 1.27 0.00905 440 3991 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.05 0.909 – 1.2 0.525 232 2168 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.04 0.97 – 1.11 0.277 946 7908 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1.17 0.922 – 1.48 0.198 79 834 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.38 0.998 – 1.92 0.0512 40 463 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.48 1.19 – 1.84 0.000414 99 843 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.15 1.02 – 1.3 0.0208 326 2192 exclusion phecode
290.1 Dementias Mental Disorders 0.922 0.758 – 1.12 0.417 116 945 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.92 0.628 – 1.35 0.667 32 269 exclusion phecode
290.12 Dementia with cerebral degenerations Mental Disorders 0.938 0.557 – 1.58 0.809 15 151 exclusion phecode
290.13 Senile dementia Mental Disorders 0.909 0.708 – 1.17 0.453 75 604 exclusion phecode
290.16 Vascular dementia Mental Disorders 1.09 0.646 – 1.85 0.742 20 144 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.19 1.02 – 1.39 0.0241 200 1357 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.94 0.814 – 1.09 0.403 208 1877 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.13 1.04 – 1.24 0.00601 540 5706 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.755 0.539 – 1.06 0.101 36 500 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.12 0.936 – 1.34 0.215 135 1160 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.14 1.03 – 1.26 0.0135 404 4403 exclusion phecode
292 Neurological disorders Mental Disorders 1.08 1.02 – 1.15 0.009 1340 8914 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.14 1.04 – 1.25 0.00608 514 4104 exclusion phecode
292.11 Aphasia Mental Disorders 0.987 0.836 – 1.17 0.882 158 1414 exclusion phecode
292.12 Symbolic dysfunction Mental Disorders 0.898 0.66 – 1.22 0.491 45 448 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.922 0.734 – 1.16 0.485 83 779 exclusion phecode
292.3 Memory loss Mental Disorders 0.913 0.822 – 1.02 0.0925 394 3874 exclusion phecode
292.4 Altered mental status Mental Disorders 1.2 1.1 – 1.32 6.58e-05 544 4644 exclusion phecode
292.5 Transient alteration of awareness Mental Disorders 1.05 0.861 – 1.28 0.636 105 944 exclusion phecode
292.6 Hallucinations Mental Disorders 1.35 0.986 – 1.85 0.0608 50 472 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.21 0.984 – 1.48 0.0714 109 942 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.08 1.01 – 1.16 0.0162 1033 8730 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.13 0.975 – 1.3 0.107 211 1890 exclusion phecode
295.1 Schizophrenia Mental Disorders 0.881 0.616 – 1.26 0.489 30 327 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.17 0.78 – 1.77 0.441 24 252 exclusion phecode
295.3 Psychosis Mental Disorders 1.18 1 – 1.38 0.0443 175 1527 exclusion phecode
296 Mood disorders Mental Disorders 1.08 1.04 – 1.14 0.000479 3358 5135 exclusion phecode
296.1 Bipolar Mental Disorders 1.22 1.08 – 1.39 0.00177 288 3055 exclusion phecode
296.2 Depression Mental Disorders 1.08 1.03 – 1.13 0.0019 3217 5134 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.08 1.03 – 1.14 0.000861 2978 5134 exclusion phecode
297 Suicidal ideation or attempt Mental Disorders 1.2 1.06 – 1.36 0.00536 273 2462 exclusion phecode
297.1 Suicidal ideation Mental Disorders 1.15 0.999 – 1.33 0.0517 211 2001 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.21 0.981 – 1.49 0.0752 99 768 exclusion phecode
300 Anxiety disorders Mental Disorders 1.1 1.06 – 1.15 1.36e-05 3742 5135 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.11 1.06 – 1.16 8.74e-06 3556 5135 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 1.07 1 – 1.14 0.0441 1339 4978 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.03 0.909 – 1.16 0.675 330 3115 exclusion phecode
300.13 Phobia Mental Disorders 1.15 1 – 1.32 0.0506 243 2450 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.781 0.618 – 0.987 0.0386 75 881 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.09 0.994 – 1.19 0.0675 590 4164 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.08 0.875 – 1.33 0.472 103 1260 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.22 1.05 – 1.42 0.0115 192 2136 exclusion phecode
301 Personality disorders Mental Disorders 1.14 0.932 – 1.39 0.204 110 1340 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.11 0.858 – 1.45 0.418 64 700 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 0.942 0.858 – 1.03 0.208 544 2894 exclusion phecode
302.1 Decreased libido Mental Disorders 0.829 0.67 – 1.02 0.0831 97 1003 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.914 0.861 – 0.971 0.0035 1620 4752 exclusion phecode
303.1 Dissociative disorder Mental Disorders 1.36 0.938 – 1.97 0.104 32 423 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.908 0.854 – 0.965 0.00192 1550 4697 exclusion phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.759 0.621 – 0.928 0.00706 120 1144 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.98 0.866 – 1.11 0.744 312 3000 exclusion phecode
304 Adjustment reaction Mental Disorders 1.03 0.963 – 1.11 0.352 930 4959 exclusion phecode
305.2 Eating disorder Mental Disorders 1.19 1 – 1.41 0.0481 145 2340 exclusion phecode
306 Other mental disorder Mental Disorders 1.04 0.938 – 1.15 0.475 464 3668 exclusion phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.03 0.862 – 1.22 0.778 156 1234 exclusion phecode
306.9 Tension headache Mental Disorders 1.02 0.879 – 1.19 0.759 189 2011 exclusion phecode
312 Conduct disorders Mental Disorders 1.22 0.955 – 1.57 0.11 74 661 exclusion phecode
312.3 Impulse control disorder Mental Disorders 0.883 0.569 – 1.37 0.58 23 218 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 1.1 0.996 – 1.21 0.06 467 4203 exclusion phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1.1 0.991 – 1.21 0.0755 423 3835 exclusion phecode
313.2 Tics and stuttering Mental Disorders 1.18 0.772 – 1.79 0.451 23 217 exclusion phecode
313.3 Autism Mental Disorders 1.15 0.656 – 2.03 0.619 12 202 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.06 0.902 – 1.25 0.475 167 1581 exclusion phecode
315.1 Learning disorder Mental Disorders 0.973 0.658 – 1.44 0.892 25 273 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.985 0.757 – 1.28 0.909 62 604 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.32 1.23 – 1.41 5.05e-15 963 7539 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.07 0.901 – 1.26 0.457 153 1360 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.22 1.13 – 1.33 1.41e-06 671 4789 exclusion phecode
317.1 Alcoholism Mental Disorders 1.25 1.14 – 1.37 9.4e-07 561 3801 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.42 1.12 – 1.8 0.00362 81 651 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.36 1.29 – 1.43 1.89e-31 2004 8160 exclusion phecode
320 Meningitis Neurological 1.2 0.97 – 1.47 0.0936 101 872 exclusion phecode
323 Encephalitis Neurological 1.52 1.11 – 2.08 0.00843 45 392 exclusion phecode
323.8 Encephalitis, non-infectious Neurological 1.5 1.06 – 2.12 0.0234 39 330 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.08 0.815 – 1.42 0.605 52 626 exclusion phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 0.859 0.439 – 1.68 0.659 10 118 exclusion phecode
327 Sleep disorders Neurological 1.04 0.988 – 1.09 0.137 2171 8803 exclusion phecode
327.1 Hypersomnia Neurological 1.01 0.889 – 1.14 0.908 266 5126 exclusion phecode
327.3 Sleep apnea Neurological 1.02 0.947 – 1.09 0.65 898 8640 exclusion phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1.11 0.887 – 1.38 0.365 81 1103 exclusion phecode
327.32 Obstructive sleep apnea Neurological 0.992 0.914 – 1.08 0.857 639 8241 exclusion phecode
327.4 Insomnia Neurological 1.02 0.957 – 1.08 0.586 1270 8485 exclusion phecode
327.41 Organic or persistent insomnia Neurological 0.987 0.873 – 1.12 0.835 286 3274 exclusion phecode
327.5 Parasomnia Neurological 0.916 0.73 – 1.15 0.451 74 1455 exclusion phecode
327.6 Circadian rhythm sleep disorder Neurological 0.918 0.695 – 1.21 0.545 54 740 exclusion phecode
327.7 Sleep related movement disorders Neurological 1.01 0.894 – 1.13 0.916 304 4527 exclusion phecode
327.71 Restless legs syndrome Neurological 1.01 0.893 – 1.15 0.831 263 4037 exclusion phecode
327.72 Sleep related leg cramps Neurological 1.11 0.699 – 1.76 0.661 18 181 exclusion phecode
331 Other cerebral degenerations Neurological 1.18 1.01 – 1.39 0.0372 175 1452 exclusion phecode
331.1 Hydrocephalus Neurological 1.18 0.935 – 1.5 0.16 69 663 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.19 0.97 – 1.46 0.0949 105 817 exclusion phecode
332 Parkinson's disease Neurological 0.951 0.773 – 1.17 0.638 99 706 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.04 0.958 – 1.14 0.328 607 5909 exclusion phecode
333.1 Essential tremor Neurological 1.06 0.902 – 1.26 0.458 163 1443 exclusion phecode
333.2 Myoclonus Neurological 1.2 0.867 – 1.67 0.268 39 365 exclusion phecode
333.4 Torsion dystonia Neurological 0.989 0.809 – 1.21 0.914 113 785 exclusion phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 0.767 0.503 – 1.17 0.217 29 168 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.05 0.912 – 1.21 0.499 223 2251 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.43 0.892 – 2.29 0.138 21 164 exclusion phecode
334.2 Anterior horn cell disease Neurological 1.08 0.703 – 1.67 0.717 25 213 exclusion phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 1.07 0.611 – 1.87 0.815 17 119 exclusion phecode
335 Multiple sclerosis Neurological 1.08 0.881 – 1.32 0.462 101 931 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.06 0.912 – 1.23 0.461 203 1628 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.37 1.07 – 1.76 0.0119 73 560 exclusion phecode
338 Pain Neurological 1.1 1.06 – 1.14 1.75e-06 4506 6507 exclusion phecode
338.1 Acute pain Neurological 1.11 1.07 – 1.16 5.12e-07 3556 6458 exclusion phecode
338.2 Chronic pain Neurological 1.12 1.07 – 1.18 7.92e-06 2162 6474 exclusion phecode
339 Other headache syndromes Neurological 1.04 0.989 – 1.09 0.133 2155 8099 exclusion phecode
340 Migraine Neurological 1.05 0.995 – 1.11 0.0728 1690 7395 exclusion phecode
340.1 Migrain with aura Neurological 1.08 1.01 – 1.16 0.0301 915 6012 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.38 0.99 – 1.91 0.0574 34 302 exclusion phecode
342 Hemiplegia Neurological 1.2 0.987 – 1.46 0.0673 110 966 exclusion phecode
343 Infantile cerebral palsy Neurological 1.24 0.839 – 1.83 0.281 25 246 exclusion phecode
344 Other paralytic syndromes Neurological 1.22 1.04 – 1.43 0.0165 171 1436 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.11 1.02 – 1.2 0.0123 654 5981 exclusion phecode
345.1 Epilepsy Neurological 1.11 0.957 – 1.29 0.167 194 1787 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.08 0.825 – 1.4 0.586 57 582 exclusion phecode
345.12 Partial epilepsy Neurological 1.07 0.896 – 1.28 0.456 138 1235 exclusion phecode
345.3 Convulsions Neurological 1.12 1.03 – 1.22 0.00635 620 5634 exclusion phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 1.06 0.759 – 1.47 0.749 40 423 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.08 0.961 – 1.21 0.2 338 3127 exclusion phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.951 0.649 – 1.39 0.796 28 262 exclusion phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 1.25 0.786 – 1.98 0.349 19 257 exclusion phecode
347 Cataplexy and narcolepsy Neurological 1.11 0.717 – 1.73 0.63 20 250 exclusion phecode
348 Other conditions of brain Neurological 1.09 0.987 – 1.21 0.0861 425 4047 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 0.992 0.862 – 1.14 0.914 215 2071 exclusion phecode
348.4 Cerebral cysts Neurological 0.783 0.594 – 1.03 0.0815 53 566 exclusion phecode
348.7 Coma Neurological 1.33 1.01 – 1.74 0.0408 57 529 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.38 1.18 – 1.6 3.41e-05 195 1750 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.09 0.993 – 1.19 0.0716 532 5180 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.12 0.974 – 1.28 0.114 234 2163 exclusion phecode
350 Abnormal movement Neurological 1.04 0.987 – 1.1 0.134 1494 9072 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.06 0.978 – 1.14 0.164 750 6804 exclusion phecode
350.2 Abnormality of gait Neurological 1.02 0.945 – 1.1 0.632 815 6558 exclusion phecode
350.3 Lack of coordination Neurological 1.03 0.911 – 1.16 0.651 293 2332 exclusion phecode
350.5 Abnormal reflex Neurological 1.24 0.905 – 1.71 0.179 43 453 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.87 0.716 – 1.06 0.159 118 1103 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.04 0.98 – 1.1 0.196 1352 8345 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.11 0.994 – 1.23 0.0651 379 4003 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.17 0.977 – 1.41 0.0864 125 1317 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.06 0.898 – 1.24 0.511 161 1792 exclusion phecode
353 Nerve root and plexus disorders Neurological 1.07 0.995 – 1.15 0.0665 843 7874 exclusion phecode
353.1 Nerve plexus lesions Neurological 1.1 0.895 – 1.35 0.363 110 956 exclusion phecode
353.2 Nerve root lesions Neurological 1.18 0.768 – 1.8 0.457 24 257 exclusion phecode
355 Complex regional/central pain syndrome Neurological 1.16 0.973 – 1.39 0.0963 131 1290 exclusion phecode
355.1 Chronic pain syndrome Neurological 1.14 0.982 – 1.33 0.0841 181 1965 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.12 1.01 – 1.24 0.0351 395 4283 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.11 1.02 – 1.21 0.0121 623 6312 exclusion phecode
358 Myoneural disorders Neurological 1.15 1.01 – 1.32 0.0411 248 2514 exclusion phecode
358.1 Myasthenia gravis Neurological 0.772 0.512 – 1.16 0.217 26 245 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.907 0.804 – 1.02 0.116 309 2559 exclusion phecode
359.1 Muscular dystrophies Neurological 0.877 0.54 – 1.42 0.596 22 153 exclusion phecode
359.2 Myopathy Neurological 0.906 0.801 – 1.03 0.119 294 2454 exclusion phecode
360 Disorders of the globe Sense Organs 0.844 0.581 – 1.23 0.375 30 266 exclusion phecode
360.2 Progressive myopia Sense Organs 0.726 0.461 – 1.14 0.166 19 128 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.957 0.81 – 1.13 0.601 156 1427 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.912 0.703 – 1.18 0.491 65 551 exclusion phecode
362 Other retinal disorders Sense Organs 0.971 0.896 – 1.05 0.48 747 4729 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.883 0.796 – 0.979 0.0183 450 3086 exclusion phecode
362.21 Macular degeneration, dry Sense Organs 0.879 0.694 – 1.11 0.287 89 722 exclusion phecode
362.22 Macular degeneration, wet Sense Organs 0.757 0.504 – 1.14 0.182 34 253 exclusion phecode
362.23 Cystoid macular degeneration of retina Sense Organs 0.9 0.725 – 1.12 0.338 88 800 exclusion phecode
362.26 Macular puckering of retina Sense Organs 0.852 0.726 – 0.999 0.0491 173 1667 exclusion phecode
362.27 Drusen (degenerative) of retina Sense Organs 1.02 0.838 – 1.25 0.815 114 930 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.887 0.795 – 0.989 0.0305 403 2769 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.08 0.922 – 1.27 0.337 174 1727 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1.17 0.945 – 1.46 0.147 87 771 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.917 0.763 – 1.1 0.356 134 1199 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.962 0.775 – 1.19 0.723 97 793 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.16 0.872 – 1.54 0.31 50 491 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.98 0.743 – 1.29 0.888 62 476 exclusion phecode
362.9 Retinal edema Sense Organs 1.05 0.801 – 1.39 0.707 59 565 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.919 0.754 – 1.12 0.402 114 962 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.854 0.673 – 1.08 0.195 73 644 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.918 0.809 – 1.04 0.185 283 2369 exclusion phecode
364.1 Corneal opacity Sense Organs 0.749 0.605 – 0.927 0.00785 104 821 exclusion phecode
364.2 Corneal edema Sense Organs 1.02 0.656 – 1.59 0.928 22 244 exclusion phecode
364.4 Corneal degenerations Sense Organs 0.902 0.741 – 1.1 0.301 118 907 exclusion phecode
364.41 Keratoconus Sense Organs 0.599 0.364 – 0.985 0.0435 21 155 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.945 0.774 – 1.15 0.583 106 998 exclusion phecode
364.51 Fuchs' dystrophy Sense Organs 1.04 0.789 – 1.38 0.772 60 530 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.736 0.439 – 1.23 0.243 17 188 exclusion phecode
365 Glaucoma Sense Organs 0.928 0.848 – 1.02 0.102 573 4343 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 0.939 0.793 – 1.11 0.468 166 1308 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.885 0.699 – 1.12 0.311 93 729 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.895 0.68 – 1.18 0.432 67 484 exclusion phecode
366 Cataract Sense Organs 0.981 0.924 – 1.04 0.519 1738 5909 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.885 0.669 – 1.17 0.394 56 430 exclusion phecode
366.2 Senile cataract Sense Organs 0.96 0.894 – 1.03 0.255 1076 5140 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.931 0.886 – 0.979 0.00532 2073 8929 exclusion phecode
367.1 Myopia Sense Organs 0.882 0.829 – 0.939 7.76e-05 1236 8271 exclusion phecode
367.2 Astigmatism Sense Organs 0.907 0.846 – 0.973 0.00605 963 7507 exclusion phecode
367.8 Hypermetropia Sense Organs 0.942 0.853 – 1.04 0.239 439 4193 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.06 0.93 – 1.2 0.405 276 2785 exclusion phecode
368 Visual disturbances Sense Organs 0.988 0.93 – 1.05 0.687 1304 9189 exclusion phecode
368.1 Amblyopia Sense Organs 1.1 0.919 – 1.31 0.305 142 1495 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.01 0.884 – 1.15 0.916 257 2306 exclusion phecode
368.3 Anisometropia Sense Organs 0.922 0.7 – 1.22 0.566 57 494 exclusion phecode
368.4 Visual field defects Sense Organs 0.934 0.809 – 1.08 0.355 202 2398 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.908 0.795 – 1.04 0.154 246 2456 exclusion phecode
368.91 Psychophysical visual disturbances Sense Organs 1.09 0.741 – 1.6 0.662 30 248 exclusion phecode
369 Infection of the eye Sense Organs 0.868 0.804 – 0.937 0.000284 768 6955 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.866 0.715 – 1.05 0.143 126 1209 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.862 0.793 – 0.936 0.000443 653 6187 exclusion phecode
370 Keratitis Sense Organs 0.833 0.746 – 0.931 0.00125 363 3031 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.751 0.579 – 0.975 0.0312 73 497 exclusion phecode
370.2 Superficial keratitis Sense Organs 0.817 0.684 – 0.977 0.0267 135 1226 exclusion phecode
370.3 Keratoconjunctivitis Sense Organs 0.968 0.824 – 1.14 0.688 170 1469 exclusion phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.769 0.571 – 1.04 0.0835 51 429 exclusion phecode
371 Inflammation of the eye Sense Organs 0.933 0.873 – 0.998 0.0424 1061 7190 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.971 0.806 – 1.17 0.754 126 1173 exclusion phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.941 0.815 – 1.09 0.406 208 2101 exclusion phecode
371.21 Allergic conjunctivitis Sense Organs 0.918 0.784 – 1.08 0.293 171 1761 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.928 0.861 – 1 0.0535 827 5881 exclusion phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 1.12 0.795 – 1.57 0.52 45 323 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.04 0.911 – 1.18 0.593 270 2280 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.924 0.851 – 1 0.064 666 5197 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.869 0.708 – 1.07 0.178 104 867 exclusion phecode
374.2 Lagophthalmos Sense Organs 1.22 0.957 – 1.57 0.108 71 518 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.989 0.865 – 1.13 0.866 248 2311 exclusion phecode
374.6 Dermatochalasis Sense Organs 0.949 0.818 – 1.1 0.49 193 2010 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.963 0.895 – 1.04 0.312 897 5809 exclusion phecode
375.1 Dry eyes Sense Organs 0.969 0.903 – 1.04 0.388 970 5921 exclusion phecode
375.2 Epiphora Sense Organs 0.885 0.725 – 1.08 0.227 109 943 exclusion phecode
376 Disorders of the orbit Sense Organs 1.11 0.898 – 1.38 0.329 85 816 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.02 0.876 – 1.19 0.807 187 2041 exclusion phecode
377.1 Optic atrophy Sense Organs 0.933 0.715 – 1.22 0.613 61 600 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.1 0.908 – 1.33 0.335 118 1325 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.12 0.994 – 1.26 0.0617 308 2832 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.05 0.903 – 1.21 0.551 195 1886 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.21 0.889 – 1.64 0.226 44 362 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.05 0.832 – 1.33 0.664 83 745 exclusion phecode
379 Other disorders of eye Sense Organs 0.955 0.893 – 1.02 0.176 1109 6488 exclusion phecode
379.1 Scleritis and episcleritis Sense Organs 0.881 0.644 – 1.21 0.43 45 414 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.94 0.869 – 1.02 0.126 783 4805 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.833 0.565 – 1.23 0.355 38 278 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 0.964 0.743 – 1.25 0.783 62 614 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.08 0.847 – 1.39 0.524 73 591 exclusion phecode
379.51 Pigmentary iris degeneration Sense Organs 0.753 0.455 – 1.25 0.269 18 138 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.91 0.8 – 1.04 0.152 268 2541 exclusion phecode
380 Disorders of external ear Sense Organs 0.904 0.824 – 0.99 0.0301 533 4433 exclusion phecode
380.1 Otitis externa Sense Organs 0.824 0.729 – 0.932 0.002 292 3392 exclusion phecode
380.4 Impacted cerumen Sense Organs 0.875 0.803 – 0.953 0.00218 622 5170 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.986 0.921 – 1.05 0.672 984 8885 exclusion phecode
381.1 Otitis media Sense Organs 1.01 0.93 – 1.09 0.879 692 7540 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.01 0.923 – 1.1 0.87 570 6551 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.906 0.821 – 1 0.0493 456 4389 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.874 0.609 – 1.25 0.466 30 367 exclusion phecode
381.9 Otorrhea Sense Organs 1.19 0.944 – 1.5 0.142 82 892 exclusion phecode
382 Otalgia Sense Organs 0.964 0.876 – 1.06 0.459 473 4795 exclusion phecode
383 Otosclerosis Sense Organs 1.04 0.727 – 1.48 0.842 33 289 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.06 0.878 – 1.27 0.56 126 1334 exclusion phecode
384.1 Myringitis Sense Organs 0.823 0.448 – 1.51 0.531 13 126 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.07 0.875 – 1.32 0.491 100 1050 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1 0.824 – 1.21 1 115 1063 exclusion phecode
385.3 Cholesteatoma Sense Organs 1.06 0.834 – 1.34 0.652 77 704 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.01 0.73 – 1.39 0.963 42 313 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.867 0.779 – 0.965 0.00894 389 4144 exclusion phecode
386.1 Meniere's disease Sense Organs 0.814 0.637 – 1.04 0.102 69 699 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.861 0.764 – 0.97 0.0136 313 3465 exclusion phecode
386.21 Central origin vertigo Sense Organs 0.848 0.74 – 0.971 0.0174 239 2681 exclusion phecode
386.3 Labyrinthitis Sense Organs 0.849 0.753 – 0.957 0.00759 305 3323 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.994 0.94 – 1.05 0.835 1533 8939 exclusion phecode
388 Other disorders of ear Sense Organs 1 0.874 – 1.15 0.989 235 2220 exclusion phecode
389 Hearing loss Sense Organs 0.978 0.927 – 1.03 0.415 1750 9108 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.915 0.851 – 0.985 0.018 866 6253 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1 0.876 – 1.15 0.946 231 2287 exclusion phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 1.21 0.856 – 1.7 0.281 45 353 exclusion phecode
389.4 Tinnitus Sense Organs 0.996 0.91 – 1.09 0.936 536 4740 exclusion phecode
389.5 Disorders of acoustic nerve Sense Organs 1.3 0.914 – 1.84 0.146 35 268 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.08 0.961 – 1.22 0.191 313 2691 exclusion phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 0.864 0.67 – 1.11 0.259 71 628 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.07 0.872 – 1.32 0.512 103 958 exclusion phecode
394.3 Aortic valve disease Circulatory System 0.878 0.589 – 1.31 0.522 25 304 exclusion phecode
394.4 Acute rheumatic heart disease Circulatory System 1.18 0.654 – 2.14 0.58 11 124 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.1 0.922 – 1.32 0.286 146 1151 exclusion phecode
395 Heart valve disorders Circulatory System 1.09 1.01 – 1.17 0.0193 885 6001 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.03 0.939 – 1.13 0.534 538 4304 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.23 1.1 – 1.37 0.000265 378 3214 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.09 0.898 – 1.32 0.387 121 1016 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.21 0.813 – 1.81 0.346 29 245 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.2 1.04 – 1.4 0.0151 205 2036 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.03 0.962 – 1.1 0.418 1089 7743 exclusion phecode
401 Hypertension Circulatory System 1.15 1.09 – 1.2 1.43e-08 3346 7626 exclusion phecode
401.1 Essential hypertension Circulatory System 1.14 1.09 – 1.2 3.58e-08 3302 7627 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.37 1.25 – 1.5 4.36e-11 559 4287 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.23 1.02 – 1.5 0.0327 115 1846 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.4 1.26 – 1.55 2.32e-10 433 3799 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.26 1.15 – 1.39 1.78e-06 489 4747 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.25 1.18 – 1.33 1.07e-12 1399 6875 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.02 0.838 – 1.24 0.834 114 1634 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.3 1.19 – 1.43 1.02e-08 581 4475 exclusion phecode
411.3 Angina pectoris Circulatory System 1.24 1.1 – 1.38 0.000235 351 3742 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.25 1.17 – 1.34 9.23e-11 1170 6026 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.09 0.71 – 1.67 0.696 22 310 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.29 1.2 – 1.39 1.83e-11 935 5489 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.26 0.989 – 1.6 0.0617 78 862 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.18 1.08 – 1.29 0.000409 537 4888 exclusion phecode
414.2 ASCVD Circulatory System 1.09 0.889 – 1.33 0.413 105 1390 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.23 1.12 – 1.34 4.65e-06 568 6409 exclusion phecode
415.1 Acute pulmonary heart disease Circulatory System 1.19 1.06 – 1.34 0.00414 307 4016 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.19 1.06 – 1.34 0.00421 306 3996 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.28 1.14 – 1.44 2.61e-05 325 3624 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.35 1.14 – 1.62 0.000751 141 1459 exclusion phecode
416 Cardiomegaly Circulatory System 1.17 1.02 – 1.35 0.03 223 2598 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.06 1.01 – 1.11 0.0139 2663 8303 exclusion phecode
418.1 Precordial pain Circulatory System 1 0.881 – 1.14 0.96 257 2916 exclusion phecode
420 Carditis Circulatory System 1.1 0.979 – 1.23 0.11 325 3199 exclusion phecode
420.1 Myocarditis Circulatory System 1.2 0.745 – 1.94 0.45 16 212 exclusion phecode
420.2 Pericarditis Circulatory System 1.03 0.876 – 1.21 0.733 176 1693 exclusion phecode
420.21 Acute pericarditis Circulatory System 0.965 0.71 – 1.31 0.822 43 368 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.12 0.69 – 1.82 0.642 21 235 exclusion phecode
420.3 Endocarditis Circulatory System 1.18 0.999 – 1.39 0.0518 162 1555 exclusion phecode
425 Cardiomyopathy Circulatory System 1.2 1.08 – 1.34 0.000956 365 3873 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.18 1.06 – 1.32 0.00301 347 3682 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.31 0.906 – 1.9 0.151 30 393 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.65 1.11 – 2.44 0.0128 26 421 exclusion phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.2 0.946 – 1.51 0.134 72 673 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.57 1 – 2.46 0.0501 24 212 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.11 1.05 – 1.17 7.2e-05 2393 6433 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.12 0.986 – 1.28 0.0802 282 2269 exclusion phecode
426.21 First degree AV block Circulatory System 1.07 0.91 – 1.25 0.42 184 1698 exclusion phecode
426.22 Mobitz II AV block Circulatory System 0.938 0.527 – 1.67 0.826 11 121 exclusion phecode
426.23 Second degree AV block Circulatory System 0.989 0.712 – 1.37 0.946 41 380 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1.01 0.796 – 1.28 0.952 85 744 exclusion phecode
426.25 Other heart block Circulatory System 1.26 0.896 – 1.77 0.185 38 337 exclusion phecode
426.3 Bundle branch block Circulatory System 1.12 1.01 – 1.25 0.0389 378 2927 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.06 0.92 – 1.21 0.439 235 2178 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.18 0.993 – 1.4 0.061 152 1610 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.837 0.558 – 1.26 0.391 24 216 exclusion phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.11 1.05 – 1.17 0.000178 2072 6305 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.27 1.06 – 1.52 0.00887 137 1431 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.19 1.05 – 1.35 0.00525 305 2302 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.24 1.06 – 1.46 0.0065 189 1569 exclusion phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.19 1.01 – 1.41 0.0382 150 1374 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.04 0.999 – 1.09 0.0561 3759 6569 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.08 0.985 – 1.19 0.101 517 4083 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.01 0.907 – 1.13 0.819 360 3264 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.19 1.03 – 1.38 0.0199 212 1952 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.06 0.983 – 1.15 0.128 880 4073 exclusion phecode
427.21 Atrial fibrillation Circulatory System 1.06 0.982 – 1.15 0.13 850 3984 exclusion phecode
427.22 Atrial flutter Circulatory System 0.986 0.867 – 1.12 0.833 270 2103 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.08 1.03 – 1.14 0.00406 1873 6497 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.946 0.756 – 1.18 0.63 89 1045 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.03 0.703 – 1.49 0.897 31 405 exclusion phecode
427.42 Cardiac arrest Circulatory System 0.995 0.78 – 1.27 0.97 76 797 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.05 0.986 – 1.11 0.134 1413 6465 exclusion phecode
427.6 Premature beats Circulatory System 0.928 0.838 – 1.03 0.151 451 3494 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 0.996 0.833 – 1.19 0.961 144 1322 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.13 1.06 – 1.2 0.000201 1198 6476 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.06 0.899 – 1.24 0.505 174 1536 exclusion phecode
427.9 Palpitations Circulatory System 0.911 0.851 – 0.974 0.00655 1079 6085 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.26 1.16 – 1.37 4.27e-08 692 5011 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.26 1.15 – 1.37 5.59e-07 592 4695 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.32 1.21 – 1.45 2.02e-09 568 4489 exclusion phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.31 1.16 – 1.48 9.14e-06 312 2812 exclusion phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.3 1.13 – 1.51 0.000344 207 2667 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.06 1.01 – 1.11 0.02 2642 8036 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.26 1.1 – 1.44 0.000743 243 2297 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.15 1.07 – 1.22 5.09e-05 1140 6729 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.03 0.984 – 1.09 0.181 2144 7990 exclusion phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.17 0.972 – 1.42 0.0971 123 1402 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.03 0.884 – 1.21 0.684 183 1622 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.14 0.871 – 1.5 0.335 60 542 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.1 0.877 – 1.37 0.417 87 759 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.01 0.788 – 1.29 0.952 73 525 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.15 1.08 – 1.23 3.54e-05 1116 6795 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.16 1.04 – 1.28 0.00618 418 3096 exclusion phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 0.941 0.712 – 1.24 0.668 60 505 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 0.696 0.41 – 1.18 0.179 16 154 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.16 1.05 – 1.27 0.00262 482 4311 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.16 1.05 – 1.28 0.0027 467 4173 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.1 1.01 – 1.21 0.0384 558 4590 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.13 1.02 – 1.24 0.0162 483 4143 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.32 1.09 – 1.59 0.00425 123 1079 exclusion phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.18 0.932 – 1.49 0.171 76 904 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.14 0.957 – 1.37 0.14 139 1421 exclusion phecode
440 Atherosclerosis Circulatory System 1.17 1.07 – 1.29 0.00124 483 3834 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.06 0.796 – 1.41 0.696 53 473 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.09 0.959 – 1.23 0.196 289 2602 exclusion phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.56 1.17 – 2.07 0.00246 57 444 exclusion phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.05 0.907 – 1.22 0.502 202 1833 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.21 1.02 – 1.43 0.0277 146 1519 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.25 1.05 – 1.49 0.0115 141 1086 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.04 0.805 – 1.34 0.763 64 493 exclusion phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.24 0.924 – 1.66 0.153 49 341 exclusion phecode
442 Other aneurysm Circulatory System 1.17 1.07 – 1.28 0.000734 538 4204 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.18 1.06 – 1.32 0.00356 359 3044 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.15 0.998 – 1.33 0.053 231 1842 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.06 0.698 – 1.63 0.771 26 331 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.21 0.821 – 1.79 0.332 26 317 exclusion phecode
442.4 Arterial dissection Circulatory System 0.833 0.602 – 1.15 0.271 41 360 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.2 0.964 – 1.49 0.103 97 829 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.11 1.03 – 1.2 0.00878 751 5181 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 0.993 0.874 – 1.13 0.915 299 1780 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.49 0.971 – 2.29 0.068 25 321 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.13 1.03 – 1.23 0.00674 633 4524 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.2 1.09 – 1.32 0.000301 470 3653 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.18 1.01 – 1.37 0.0325 205 1687 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.08 0.861 – 1.36 0.492 85 563 exclusion phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 0.908 0.626 – 1.32 0.61 33 254 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.06 0.869 – 1.3 0.552 112 996 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.814 0.552 – 1.2 0.298 29 233 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.28 0.74 – 2.23 0.374 17 155 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.02 0.802 – 1.31 0.845 74 611 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.19 1.08 – 1.3 0.000225 541 4593 exclusion phecode
447.1 Stricture of artery Circulatory System 1.26 1.04 – 1.52 0.016 127 1103 exclusion phecode
447.7 Aortic ectasia Circulatory System 1.26 1.04 – 1.53 0.0161 110 1448 exclusion phecode
448 Disease of capillaries Circulatory System 0.871 0.775 – 0.979 0.0206 338 2641 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.06 0.959 – 1.17 0.252 431 4714 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.961 0.816 – 1.13 0.629 154 1664 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.03 0.75 – 1.42 0.843 39 565 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1.09 1.02 – 1.17 0.0125 915 7002 exclusion phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1.24 0.881 – 1.73 0.219 32 571 exclusion phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1.07 0.983 – 1.17 0.117 596 6075 exclusion phecode
452.8 Postphlebitic syndrome Circulatory System 0.807 0.52 – 1.25 0.339 21 348 exclusion phecode
453 Chronic venous hypertension Circulatory System 0.932 0.681 – 1.27 0.657 47 476 exclusion phecode
454 Varicose veins Circulatory System 1.03 0.944 – 1.12 0.531 608 5675 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1.03 0.935 – 1.13 0.584 514 4894 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.969 0.861 – 1.09 0.606 316 3463 exclusion phecode
455 Hemorrhoids Circulatory System 0.931 0.875 – 0.99 0.023 1282 6964 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.982 0.899 – 1.07 0.683 567 5684 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.11 0.991 – 1.24 0.0726 364 3134 exclusion phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.16 0.876 – 1.53 0.305 55 598 exclusion phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.1 0.979 – 1.23 0.109 336 2996 exclusion phecode
458 Hypotension Circulatory System 1.25 1.18 – 1.34 5.52e-12 1176 7346 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.15 1.02 – 1.3 0.0191 332 2790 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.27 1.11 – 1.46 0.000478 240 2177 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.26 1.18 – 1.35 1.4e-11 1063 7007 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.16 1.09 – 1.23 5.56e-07 1488 8249 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.14 0.984 – 1.33 0.0793 198 1796 exclusion phecode
459.7 Blood vessel replaced Circulatory System 1.28 1.12 – 1.46 0.000217 270 2697 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.13 1.06 – 1.2 0.00018 1216 7763 exclusion phecode
464 Acute sinusitis Respiratory 0.943 0.882 – 1.01 0.0797 1058 7669 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.949 0.904 – 0.995 0.0302 2314 8379 exclusion phecode
465.2 Acute pharyngitis Respiratory 0.906 0.854 – 0.961 0.00112 1387 7845 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.05 0.849 – 1.29 0.665 99 1091 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.978 0.885 – 1.08 0.666 447 4242 exclusion phecode
471 Nasal polyps Respiratory 0.912 0.757 – 1.1 0.332 128 1347 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.865 0.777 – 0.964 0.00874 386 4089 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.1 1.01 – 1.18 0.0204 765 5620 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.58 0.915 – 2.72 0.101 15 141 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.19 1 – 1.42 0.0472 152 1442 exclusion phecode
473.4 Voice disturbance Respiratory 1.11 1.02 – 1.21 0.0181 621 4837 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1.01 0.893 – 1.15 0.856 289 2465 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.08 0.895 – 1.3 0.427 129 1165 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.982 0.853 – 1.13 0.803 220 2021 exclusion phecode
475 Chronic sinusitis Respiratory 1.02 0.948 – 1.09 0.67 987 6534 exclusion phecode
475.9 Postnasal drip Respiratory 1 0.86 – 1.16 0.999 196 1995 exclusion phecode
476 Allergic rhinitis Respiratory 0.945 0.903 – 0.989 0.0143 2895 6585 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.12 0.982 – 1.27 0.0915 266 2574 exclusion phecode
478 Throat pain Respiratory 1.14 0.941 – 1.39 0.177 120 1024 exclusion phecode
479 Other upper respiratory disease Respiratory 1.04 0.979 – 1.11 0.203 1311 6567 exclusion phecode
480 Pneumonia Respiratory 1.11 1.04 – 1.18 0.000801 1287 8722 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.1 0.977 – 1.23 0.117 309 2487 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.21 1.01 – 1.44 0.0351 139 1193 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.12 0.825 – 1.51 0.474 50 359 exclusion phecode
480.13 MRSA pneumonia Respiratory 1.76 1.07 – 2.9 0.0258 20 272 exclusion phecode
480.2 Viral pneumonia Respiratory 1.28 0.921 – 1.77 0.143 41 379 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.27 0.932 – 1.73 0.13 47 332 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.39 0.995 – 1.93 0.0533 39 297 exclusion phecode
481 Influenza Respiratory 1.02 0.9 – 1.15 0.78 298 3205 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.942 0.868 – 1.02 0.156 646 7069 exclusion phecode
495 Asthma Respiratory 1.09 1.03 – 1.15 0.00157 1770 8173 exclusion phecode
495.1 Chronic obstructive asthma Respiratory 1.29 1.01 – 1.66 0.0422 66 857 exclusion phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 0.805 0.36 – 1.8 0.597 8 159 exclusion phecode
495.2 Asthma with exacerbation Respiratory 0.987 0.879 – 1.11 0.823 321 4419 exclusion phecode
496 Chronic airway obstruction Respiratory 1.34 1.26 – 1.43 1.58e-18 1192 6161 exclusion phecode
496.1 Emphysema Respiratory 1.4 1.28 – 1.54 4.86e-13 559 3825 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.44 1.34 – 1.56 4.99e-21 840 5653 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.47 1.36 – 1.59 1.52e-21 770 5285 exclusion phecode
496.3 Bronchiectasis Respiratory 1.07 0.905 – 1.26 0.439 170 1143 exclusion phecode
497 Bronchitis Respiratory 1.08 0.97 – 1.21 0.156 365 4623 exclusion phecode
498 Acute bronchospasm Respiratory 1.26 1.02 – 1.56 0.0324 97 1271 exclusion phecode
499 Cystic fibrosis Respiratory 1.06 0.795 – 1.41 0.703 57 408 exclusion phecode
500 Lung disease due to external agents Respiratory 1.29 1.06 – 1.57 0.00969 122 1106 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.25 0.779 – 2.02 0.35 23 203 exclusion phecode
500.2 Pneumoconiosis Respiratory 1.87 0.828 – 4.22 0.132 10 121 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.45 1.22 – 1.72 1.78e-05 173 1183 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.08 0.916 – 1.27 0.369 165 1637 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.2 1.02 – 1.41 0.0272 164 1657 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.06 0.877 – 1.28 0.544 126 1197 exclusion phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 0.938 0.724 – 1.22 0.629 66 623 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.14 1.02 – 1.27 0.0263 342 3215 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.16 1.07 – 1.25 0.000296 701 5222 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.22 1.13 – 1.33 1.62e-06 659 5524 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.26 1.14 – 1.38 3.18e-06 475 4713 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.22 1.13 – 1.32 2.21e-07 808 6265 exclusion phecode
509.1 Respiratory failure Respiratory 1.38 1.24 – 1.53 1.68e-09 427 3812 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.19 1.05 – 1.36 0.00851 269 2349 exclusion phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.21 1.08 – 1.35 0.000682 385 3241 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.28 1.13 – 1.44 5.52e-05 317 3416 exclusion phecode
510 Other diseases of lung Respiratory 1.1 1.03 – 1.17 0.00336 1194 7846 exclusion phecode
510.2 Lung transplant Respiratory 1.32 0.969 – 1.79 0.0785 51 373 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.1 1.05 – 1.14 8.39e-06 3890 7132 exclusion phecode
512.1 Wheezing Respiratory 1.39 1.2 – 1.6 5.46e-06 215 3292 exclusion phecode
512.2 Painful respiration Respiratory 1.09 0.995 – 1.19 0.0636 552 5258 exclusion phecode
512.3 Abnormal chest sounds Respiratory 1.25 0.975 – 1.61 0.0783 73 608 exclusion phecode
512.7 Shortness of breath Respiratory 1.15 1.09 – 1.21 3.05e-07 1926 7104 exclusion phecode
512.8 Cough Respiratory 1.05 1 – 1.11 0.0457 2033 7127 exclusion phecode
512.9 Other dyspnea Respiratory 1.12 1.06 – 1.18 1.65e-05 1997 7106 exclusion phecode
513 Respiratory abnormalities Respiratory 1.14 1.08 – 1.19 7.79e-08 2470 8537 exclusion phecode
513.3 Hypoventilation Respiratory 1.04 0.872 – 1.25 0.641 128 1878 exclusion phecode
513.31 Apnea Respiratory 1.02 0.804 – 1.29 0.873 76 960 exclusion phecode
513.32 Orthopnea Respiratory 1.08 0.755 – 1.56 0.661 28 412 exclusion phecode
513.4 Hyperventilation Respiratory 1.34 1.08 – 1.67 0.00823 94 1120 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.59 1.14 – 2.2 0.00614 40 488 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.12 1.06 – 1.2 0.000255 1193 7434 exclusion phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 0.891 0.669 – 1.19 0.428 52 543 exclusion phecode
514.2 Solitary pulmonary nodule Respiratory 1.11 1.02 – 1.21 0.0116 652 5644 exclusion phecode
516 Abnormal sputum Respiratory 1.14 0.969 – 1.34 0.114 169 1494 exclusion phecode
516.1 Hemoptysis Respiratory 1.16 0.968 – 1.38 0.109 137 1263 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.14 1.08 – 1.21 6.57e-06 1418 9074 exclusion phecode
519.1 Tracheostomy complications Respiratory 1.42 1.09 – 1.84 0.00849 64 431 exclusion phecode
519.2 Respiratory complications Respiratory 1.04 0.836 – 1.29 0.742 94 928 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.07 0.962 – 1.19 0.215 382 3472 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.19 1.12 – 1.28 1.91e-07 1037 7618 exclusion phecode
520 Disorders of tooth development Digestive 1.1 0.908 – 1.33 0.333 120 952 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.41 1.04 – 1.92 0.0285 52 380 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.997 0.791 – 1.26 0.982 77 638 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.42 1.24 – 1.62 3.75e-07 250 1935 exclusion phecode
521.1 Dental caries Digestive 1.43 1.24 – 1.64 5.84e-07 234 1781 exclusion phecode
521.2 Dental abrasion, erosion and attrition Digestive 0.96 0.517 – 1.78 0.897 8 116 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.37 1.13 – 1.66 0.00162 111 1178 exclusion phecode
522.5 Periapical abscess Digestive 1.51 1.22 – 1.87 0.000142 95 1040 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.31 1.11 – 1.54 0.00106 163 1547 exclusion phecode
523.1 Gingivitis Digestive 1.18 0.845 – 1.65 0.331 38 340 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.46 1.14 – 1.87 0.00247 71 779 exclusion phecode
523.31 Acute periodontitis Digestive 1.39 1.07 – 1.81 0.0128 56 663 exclusion phecode
523.32 Chronic periodontitis Digestive 1.51 1.02 – 2.25 0.0408 30 246 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.04 0.874 – 1.24 0.647 160 1055 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.979 0.794 – 1.21 0.84 110 683 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.4 1.23 – 1.59 2.04e-07 278 2423 exclusion phecode
525.1 Loss of teeth or edentulism Digestive 1.29 1.06 – 1.59 0.0134 105 894 exclusion phecode
526 Diseases of the jaws Digestive 1.04 0.967 – 1.12 0.278 817 6561 exclusion phecode
526.1 Cysts of the jaws Digestive 0.822 0.628 – 1.08 0.154 53 512 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.997 0.816 – 1.22 0.975 123 786 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 0.976 0.883 – 1.08 0.637 453 3884 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.987 0.884 – 1.1 0.814 371 3116 exclusion phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 1.01 0.879 – 1.16 0.89 237 2005 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 1.5 1.21 – 1.88 3e-04 104 654 exclusion phecode
526.8 Exostosis of jaw Digestive 1.73 1.05 – 2.86 0.0329 21 98 exclusion phecode
526.9 Jaw disease NOS Digestive 1.2 1.02 – 1.42 0.0276 173 1118 exclusion phecode
527 Diseases of the salivary glands Digestive 1.04 0.943 – 1.15 0.409 425 3834 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.02 0.603 – 1.72 0.943 14 141 exclusion phecode
527.2 Sialoadenitis Digestive 1.09 0.874 – 1.35 0.454 95 913 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.11 0.962 – 1.27 0.159 226 1880 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1 0.753 – 1.33 0.996 54 529 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.05 0.976 – 1.14 0.18 751 5899 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.01 0.872 – 1.18 0.871 200 1559 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.14 0.855 – 1.53 0.366 51 490 exclusion phecode
528.12 Oral aphthae Digestive 0.837 0.655 – 1.07 0.155 69 559 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.61 1.26 – 2.06 0.000122 74 528 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.678 0.466 – 0.986 0.0419 33 296 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.748 0.473 – 1.18 0.215 23 176 exclusion phecode
528.5 Diseases of lips Digestive 1.05 0.882 – 1.26 0.557 142 1063 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.09 0.762 – 1.56 0.64 34 277 exclusion phecode
528.7 Sialolithiasis Digestive 1.18 0.87 – 1.6 0.286 44 339 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 0.962 0.817 – 1.13 0.644 156 1409 exclusion phecode
529.1 Glossitis Digestive 1.06 0.732 – 1.54 0.754 30 268 exclusion phecode
529.6 Glossodynia Digestive 0.797 0.555 – 1.14 0.218 30 321 exclusion phecode
530 Diseases of esophagus Digestive 1.16 1.11 – 1.21 2.94e-11 3202 7330 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.16 1.11 – 1.21 1.14e-10 3046 7330 exclusion phecode
530.11 GERD Digestive 1.16 1.11 – 1.22 8.91e-11 2914 7329 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.27 1.01 – 1.58 0.0379 84 907 exclusion phecode
530.13 Barrett's esophagus Digestive 1.27 1.04 – 1.55 0.0177 106 1472 exclusion phecode
530.14 Reflux esophagitis Digestive 1.16 1.03 – 1.29 0.0105 367 4224 exclusion phecode
530.15 Eosinophilic esophagitis Digestive 1.08 0.8 – 1.45 0.626 49 627 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.27 1.06 – 1.51 0.00811 137 1353 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1.14 0.99 – 1.32 0.0692 217 2006 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.22 1.02 – 1.46 0.0305 131 1344 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.841 0.579 – 1.22 0.366 43 257 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.67 1.08 – 2.56 0.02 22 185 exclusion phecode
530.9 Heartburn Digestive 1.2 1.07 – 1.36 0.00242 300 3782 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.24 1.12 – 1.36 3.35e-05 435 4455 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.23 0.984 – 1.53 0.0686 81 733 exclusion phecode
531.2 Gastric ulcer Digestive 1.3 1.14 – 1.48 9.49e-05 247 2646 exclusion phecode
531.3 Duodenal ulcer Digestive 1.25 1.02 – 1.54 0.0329 99 883 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.22 1.05 – 1.43 0.0113 180 1724 exclusion phecode
531.5 Gastrojejunal ulcer Digestive 1.15 0.826 – 1.59 0.415 38 323 exclusion phecode
532 Dysphagia Digestive 1.26 1.18 – 1.33 2.6e-13 1388 6859 exclusion phecode
535 Gastritis and duodenitis Digestive 1.05 0.967 – 1.14 0.241 611 6299 exclusion phecode
535.1 Acute gastritis Digestive 1.22 1.07 – 1.39 0.00374 238 2623 exclusion phecode
535.2 Atrophic gastritis Digestive 0.937 0.737 – 1.19 0.599 76 786 exclusion phecode
535.6 Duodenitis Digestive 0.944 0.738 – 1.21 0.645 67 710 exclusion phecode
535.8 Other specified gastritis Digestive 1.02 0.863 – 1.21 0.787 142 1439 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.988 0.877 – 1.11 0.845 294 2905 exclusion phecode
536 Disorders of function of stomach Digestive 1.13 1.04 – 1.22 0.00223 771 6521 exclusion phecode
536.3 Gastroparesis Digestive 1.24 1.06 – 1.45 0.00717 184 1584 exclusion phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.33 1.1 – 1.6 0.00314 137 858 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.12 1.02 – 1.22 0.0184 544 4961 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.17 1.08 – 1.26 6.86e-05 746 6762 exclusion phecode
537.1 Lesions of stomach and duodenum Digestive 1.46 1.04 – 2.05 0.0279 34 309 exclusion phecode
539 Bariatric surgery Digestive 2.3 1.81 – 2.93 7.89e-12 73 3739 exclusion phecode
540 Appendiceal conditions Digestive 1 0.831 – 1.21 0.994 126 1222 exclusion phecode
540.1 Appendicitis Digestive 0.964 0.787 – 1.18 0.724 110 1037 exclusion phecode
540.11 Acute appendicitis Digestive 0.967 0.776 – 1.2 0.765 95 855 exclusion phecode
550 Abdominal hernia Digestive 0.994 0.935 – 1.06 0.858 1207 8816 exclusion phecode
550.1 Inguinal hernia Digestive 0.875 0.79 – 0.968 0.00972 445 3017 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.06 0.961 – 1.17 0.244 446 5737 exclusion phecode
550.3 Femoral hernia Digestive 0.838 0.611 – 1.15 0.27 51 272 exclusion phecode
550.4 Umbilical hernia Digestive 0.887 0.755 – 1.04 0.145 155 2658 exclusion phecode
550.5 Ventral hernia Digestive 1.12 1.01 – 1.26 0.0398 340 4744 exclusion phecode
550.6 Incisional hernia Digestive 1.17 1.01 – 1.36 0.0409 177 2826 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.17 1.06 – 1.29 0.00227 466 3704 exclusion phecode
555.1 Regional enteritis Digestive 1.31 1.15 – 1.48 1.97e-05 313 2269 exclusion phecode
555.2 Ulcerative colitis Digestive 1.04 0.912 – 1.18 0.563 273 2180 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 0.969 0.819 – 1.15 0.711 175 1300 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.13 0.956 – 1.33 0.154 159 1371 exclusion phecode
556.1 Ulceration of intestine Digestive 1.13 0.943 – 1.34 0.189 139 1217 exclusion phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 1.23 0.886 – 1.69 0.219 40 393 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.16 1.05 – 1.3 0.00576 381 4374 exclusion phecode
557.1 Celiac disease Digestive 1.15 0.961 – 1.37 0.127 155 1065 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.12 1.04 – 1.2 0.00243 893 6442 exclusion phecode
559 Ileostomy status Digestive 1.23 1.07 – 1.41 0.00264 248 2053 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.18 1.09 – 1.27 2.26e-05 792 5625 exclusion phecode
560.1 Paralytic ileus Digestive 1.14 1.02 – 1.27 0.0171 385 3274 exclusion phecode
560.2 Impaction of intestine Digestive 1.25 1.02 – 1.53 0.0283 111 930 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.14 0.904 – 1.43 0.274 90 613 exclusion phecode
560.4 Other intestinal obstruction Digestive 1.22 1.11 – 1.34 7.54e-05 482 3597 exclusion phecode
561 Symptoms involving digestive system Digestive 1.05 0.968 – 1.14 0.231 672 5257 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 0.974 0.906 – 1.05 0.465 1035 4936 exclusion phecode
562.1 Diverticulosis Digestive 0.968 0.901 – 1.04 0.37 1026 4925 exclusion phecode
562.2 Diverticulitis Digestive 1.14 0.996 – 1.3 0.0572 249 3143 exclusion phecode
564 Functional digestive disorders Digestive 1.08 1.03 – 1.13 0.000629 2747 6964 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.04 0.97 – 1.12 0.25 904 5634 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.13 1.04 – 1.23 0.00295 685 5931 exclusion phecode
565 Anal and rectal conditions Digestive 0.987 0.916 – 1.06 0.725 818 6940 exclusion phecode
565.1 Anal and rectal polyp Digestive 0.872 0.76 – 1 0.0508 236 2505 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.33 1.18 – 1.49 1.5e-06 336 2915 exclusion phecode
568 Other disorders of peritoneum Digestive 1.13 1.02 – 1.26 0.0242 372 3676 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.12 0.98 – 1.27 0.0988 262 2676 exclusion phecode
569 Other disorders of intestine Digestive 1.09 1.04 – 1.15 0.00117 1700 8326 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.25 0.983 – 1.58 0.0694 81 697 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.21 1.08 – 1.37 0.00152 304 3101 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.15 1.06 – 1.24 0.000737 692 7454 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.13 1.04 – 1.23 0.0031 622 7333 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.31 1.12 – 1.53 0.000789 178 1964 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.33 0.952 – 1.85 0.0945 38 370 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.34 1.15 – 1.55 0.000174 201 1842 exclusion phecode
571.81 Portal hypertension Digestive 1.35 1.1 – 1.66 0.00409 106 1127 exclusion phecode
572 Ascites (non malignant) Digestive 1.2 1.1 – 1.3 5.19e-05 575 5073 exclusion phecode
573 Other disorders of liver Digestive 1.11 1.04 – 1.18 0.00271 1049 7805 exclusion phecode
573.1 Chronic passive congestion of liver Digestive 1.64 1.09 – 2.45 0.017 33 296 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.2 0.94 – 1.53 0.143 71 550 exclusion phecode
573.3 Hepatomegaly Digestive 1.23 0.994 – 1.52 0.057 93 1082 exclusion phecode
573.4 Acute and subacute necrosis of liver Digestive 1.13 0.889 – 1.43 0.32 80 635 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.17 1.02 – 1.34 0.0269 232 1937 exclusion phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.13 1.03 – 1.23 0.00748 560 5842 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.09 0.996 – 1.19 0.0617 572 6092 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.12 1.04 – 1.19 0.0014 969 7954 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.13 1.03 – 1.24 0.0105 520 7209 exclusion phecode
574.1 Cholelithiasis Digestive 1.11 1.01 – 1.23 0.0308 455 6806 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.982 0.732 – 1.32 0.902 46 772 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.928 0.737 – 1.17 0.528 77 1290 exclusion phecode
574.2 Calculus of bile duct Digestive 1.04 0.885 – 1.23 0.608 161 1979 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.18 0.99 – 1.41 0.0651 137 1871 exclusion phecode
575 Other biliary tract disease Digestive 1.14 1.03 – 1.25 0.00735 496 5142 exclusion phecode
575.1 Cholangitis Digestive 1.2 0.98 – 1.48 0.0775 101 731 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.27 1.08 – 1.49 0.003 173 1349 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.759 0.555 – 1.04 0.0841 40 529 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.17 0.999 – 1.37 0.0511 170 2192 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.19 1.06 – 1.34 0.00426 302 2508 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1 0.761 – 1.33 0.975 56 590 exclusion phecode
577 Diseases of pancreas Digestive 1.17 1.07 – 1.27 0.00069 554 4716 exclusion phecode
577.1 Acute pancreatitis Digestive 1.29 1.14 – 1.46 5.85e-05 285 2551 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.53 1.27 – 1.84 8.14e-06 138 982 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.12 0.942 – 1.33 0.199 158 1167 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.07 1 – 1.15 0.0372 1007 8632 exclusion phecode
578.1 Hematemesis Digestive 1.23 1.03 – 1.48 0.025 117 1060 exclusion phecode
578.2 Blood in stool Digestive 1.08 0.993 – 1.18 0.0733 600 5938 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.02 0.926 – 1.12 0.708 476 5034 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.13 1.02 – 1.27 0.0255 349 3224 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.12 1.05 – 1.2 0.00123 975 7967 exclusion phecode
579.2 Splenomegaly Digestive 1.15 0.962 – 1.38 0.124 121 1577 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.11 0.991 – 1.25 0.0717 326 3092 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.28 1.14 – 1.44 3.31e-05 327 3423 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.35 1.09 – 1.68 0.00681 93 846 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.33 0.916 – 1.93 0.134 30 314 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.49 0.932 – 2.39 0.0955 17 241 exclusion phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.14 0.707 – 1.85 0.582 13 135 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.46 1.13 – 1.88 0.00363 71 621 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.13 0.827 – 1.54 0.444 37 466 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.32 1.15 – 1.51 4.9e-05 249 2607 exclusion phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.34 1.11 – 1.6 0.00174 138 1500 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.34 1.13 – 1.59 0.000746 147 1449 exclusion phecode
580.4 Renal sclerosis, NOS Genitourinary 1.39 1.09 – 1.79 0.00891 71 754 exclusion phecode
585 Renal failure Genitourinary 1.29 1.21 – 1.37 4.12e-16 1352 7675 exclusion phecode
585.1 Acute renal failure Genitourinary 1.34 1.24 – 1.45 2.92e-14 803 6037 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.26 1.08 – 1.47 0.00317 182 1711 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.27 1.18 – 1.36 3.15e-11 985 6716 exclusion phecode
585.31 Renal dialysis Genitourinary 1.39 1.19 – 1.64 5.44e-05 176 1530 exclusion phecode
585.32 End stage renal disease Genitourinary 1.48 1.29 – 1.7 3.02e-08 238 2054 exclusion phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.27 1.16 – 1.41 1e-06 492 4489 exclusion phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.3 1.11 – 1.51 0.000925 187 1901 exclusion phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.27 1.1 – 1.46 0.000829 232 2389 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.13 1.07 – 1.2 2.74e-05 1476 8474 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.22 0.975 – 1.52 0.0823 86 891 exclusion phecode
586.11 Small kidney Genitourinary 1.19 0.882 – 1.61 0.253 45 515 exclusion phecode
586.12 Vesicoureteral reflux Genitourinary 1.15 0.843 – 1.56 0.38 40 401 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.02 0.897 – 1.17 0.738 257 2645 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.2 0.879 – 1.64 0.25 44 391 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.06 0.958 – 1.18 0.243 391 3829 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.35 1.18 – 1.55 1.94e-05 231 1742 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.29 1.12 – 1.49 0.00042 220 2000 exclusion phecode
588.1 Renal osteodystrophy Genitourinary 1.27 1 – 1.6 0.0465 85 582 exclusion phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.25 1.06 – 1.47 0.00946 155 1556 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.22 1.05 – 1.41 0.00853 210 2132 exclusion phecode
590 Pyelonephritis Genitourinary 1.07 0.953 – 1.2 0.254 326 3559 exclusion phecode
591 Urinary tract infection Genitourinary 1 0.955 – 1.05 0.909 2300 7506 exclusion phecode
592 Cystitis and urethritis Genitourinary 0.995 0.92 – 1.08 0.905 740 5943 exclusion phecode
592.1 Cystitis Genitourinary 1.01 0.934 – 1.1 0.753 698 5747 exclusion phecode
592.11 Acute cystitis Genitourinary 0.999 0.9 – 1.11 0.979 421 4051 exclusion phecode
592.12 Chronic cystitis Genitourinary 1.1 0.814 – 1.49 0.536 49 587 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.04 0.869 – 1.25 0.646 139 1166 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.919 0.706 – 1.2 0.532 62 490 exclusion phecode
593 Hematuria Genitourinary 0.986 0.92 – 1.06 0.684 970 7381 exclusion phecode
593.1 Gross hematuria Genitourinary 0.888 0.785 – 1 0.0582 285 2873 exclusion phecode
593.2 Microscopic hematuria Genitourinary 0.945 0.818 – 1.09 0.438 229 2282 exclusion phecode
594 Urinary calculus Genitourinary 1.06 0.998 – 1.13 0.0579 1206 9137 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.05 0.986 – 1.12 0.128 1117 9085 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.02 0.816 – 1.29 0.835 80 715 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.01 0.884 – 1.16 0.871 234 3001 exclusion phecode
594.8 Renal colic Genitourinary 1.18 0.924 – 1.51 0.182 70 882 exclusion phecode
595 Hydronephrosis Genitourinary 1.16 1.04 – 1.3 0.0064 382 3817 exclusion phecode
596 Other disorders of bladder Genitourinary 0.964 0.888 – 1.05 0.375 673 5962 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.04 0.818 – 1.31 0.765 75 680 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 0.977 0.876 – 1.09 0.669 381 3817 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.969 0.855 – 1.1 0.617 278 2509 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.871 0.725 – 1.05 0.143 129 1171 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.04 0.904 – 1.2 0.57 217 2148 exclusion phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.19 0.871 – 1.61 0.28 40 454 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.41 0.934 – 2.13 0.102 25 281 exclusion phecode
598.4 Other cells and casts in urine Genitourinary 1.37 0.884 – 2.13 0.159 23 247 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.967 0.926 – 1.01 0.14 3011 7568 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.755 0.628 – 0.908 0.00281 132 1245 exclusion phecode
599.2 Retention of urine Genitourinary 0.986 0.92 – 1.06 0.68 1038 6664 exclusion phecode
599.3 Dysuria Genitourinary 0.98 0.916 – 1.05 0.544 1049 6736 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.959 0.894 – 1.03 0.243 972 6365 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 0.955 0.894 – 1.02 0.17 1105 6871 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.19 0.999 – 1.43 0.0519 142 1204 exclusion phecode
599.7 Urethral discharge Genitourinary 0.744 0.473 – 1.17 0.202 18 194 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 0.909 0.851 – 0.972 0.00493 1114 6590 exclusion phecode
599.9 Other abnormality of urination Genitourinary 0.892 0.819 – 0.972 0.0088 621 5727 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.889 0.805 – 0.983 0.0211 641 1750 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 0.964 0.82 – 1.13 0.657 157 1631 exclusion phecode
601.1 Prostatitis Genitourinary 0.908 0.714 – 1.16 0.434 76 724 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.952 0.632 – 1.43 0.814 31 199 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1.26 0.687 – 2.3 0.459 12 142 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.961 0.752 – 1.23 0.749 61 681 exclusion phecode
601.4 Balanoposthitis Genitourinary 1.03 0.607 – 1.76 0.9 13 226 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.12 0.759 – 1.65 0.568 23 286 exclusion phecode
602 Other disorders of prostate Genitourinary 1.03 0.785 – 1.34 0.843 67 483 exclusion phecode
602.3 Dysplasia of prostate Genitourinary 1.65 0.849 – 3.22 0.139 15 93 exclusion phecode
603 Other disorders of testis Genitourinary 1.03 0.836 – 1.27 0.767 86 836 exclusion phecode
603.1 Hydrocele Genitourinary 0.993 0.746 – 1.32 0.961 47 521 exclusion phecode
603.2 Spermatocele Genitourinary 0.893 0.659 – 1.21 0.466 40 283 exclusion phecode
604 Disorders of penis Genitourinary 0.989 0.833 – 1.18 0.901 133 1209 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.21 0.766 – 1.93 0.409 16 263 exclusion phecode
604.3 Peyronie's disease Genitourinary 0.88 0.656 – 1.18 0.395 48 330 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.923 0.836 – 1.02 0.112 496 2198 exclusion phecode
608 Other disorders of male genital organs Genitourinary 0.957 0.854 – 1.07 0.456 317 2629 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.981 0.792 – 1.21 0.858 77 860 exclusion phecode
609.1 Infertility, male Genitourinary 1.11 0.871 – 1.42 0.39 56 653 exclusion phecode
609.11 Azoospermia and oligospermia Genitourinary 1.5 0.948 – 2.37 0.0837 14 230 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.593 0.399 – 0.882 0.00989 24 295 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.871 0.812 – 0.933 9.35e-05 1103 4593 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.881 0.799 – 0.972 0.0112 506 3675 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 0.678 0.403 – 1.14 0.144 19 147 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.857 0.794 – 0.925 7.22e-05 879 4543 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.903 0.808 – 1.01 0.0709 390 3126 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.871 0.822 – 0.922 2.17e-06 1789 4939 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.84 0.789 – 0.895 5.06e-08 1489 4263 exclusion phecode
611.11 Mammographic microcalcification Genitourinary 0.829 0.739 – 0.931 0.0015 364 2535 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.887 0.828 – 0.95 0.000631 1089 4931 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.84 0.73 – 0.967 0.0152 232 2773 exclusion phecode
612.1 Galactorrhea Genitourinary 0.823 0.578 – 1.17 0.28 34 435 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.862 0.719 – 1.03 0.111 135 2033 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 0.651 0.435 – 0.974 0.0366 36 230 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.916 0.857 – 0.978 0.00906 1132 5978 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 0.933 0.789 – 1.1 0.42 152 1564 exclusion phecode
613.5 Mastodynia Genitourinary 0.98 0.889 – 1.08 0.681 489 4210 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.88 0.772 – 1 0.053 269 2329 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 0.854 0.751 – 0.972 0.017 273 2469 exclusion phecode
613.9 Breast disorder NOS Genitourinary 0.906 0.817 – 1.01 0.0652 424 3595 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.932 0.871 – 0.998 0.0433 1089 5485 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1 0.795 – 1.26 0.981 84 897 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.02 0.853 – 1.23 0.804 140 1356 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.07 0.707 – 1.61 0.758 31 282 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.06 0.798 – 1.4 0.699 61 500 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.962 0.751 – 1.23 0.758 72 687 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.937 0.692 – 1.27 0.671 52 476 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.909 0.845 – 0.977 0.0096 944 5450 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.03 0.796 – 1.32 0.838 71 767 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.917 0.849 – 0.99 0.0262 820 5315 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.01 0.712 – 1.43 0.954 37 368 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.745 0.567 – 0.979 0.0344 59 631 exclusion phecode
615 Endometriosis Genitourinary 0.953 0.859 – 1.06 0.354 433 3999 exclusion phecode
618 Genital prolapse Genitourinary 0.951 0.865 – 1.05 0.302 508 4723 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.937 0.835 – 1.05 0.265 345 3445 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.958 0.806 – 1.14 0.624 145 1379 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.941 0.734 – 1.21 0.63 73 757 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.01 0.827 – 1.24 0.894 103 1118 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 0.973 0.919 – 1.03 0.354 1658 5216 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.947 0.844 – 1.06 0.353 344 3480 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 1.01 0.849 – 1.19 0.944 154 1622 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.92 0.777 – 1.09 0.333 163 1311 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.961 0.888 – 1.04 0.327 760 5121 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1 0.89 – 1.13 0.981 326 3206 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1.1 0.904 – 1.33 0.346 118 1063 exclusion phecode
620.1 Dysplasia of cervix Genitourinary 0.983 0.745 – 1.3 0.904 57 513 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.765 0.593 – 0.988 0.0405 63 1163 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.879 0.786 – 0.984 0.0254 353 3805 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.827 0.725 – 0.943 0.00466 258 2965 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 0.942 0.778 – 1.14 0.543 123 1162 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 0.992 0.861 – 1.14 0.915 220 2246 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.973 0.878 – 1.08 0.602 437 3600 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.938 0.71 – 1.24 0.65 55 525 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 1.11 0.738 – 1.68 0.611 28 159 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.846 0.76 – 0.942 0.00237 388 3990 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.928 0.875 – 0.983 0.0113 1668 4852 exclusion phecode
625.1 Dyspareunia Genitourinary 0.895 0.804 – 0.997 0.0431 405 3480 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.891 0.839 – 0.945 0.000138 1676 4395 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.889 0.831 – 0.951 0.000603 1227 4097 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.912 0.805 – 1.03 0.144 304 2629 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 0.913 0.831 – 1 0.0555 547 3486 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.875 0.797 – 0.961 0.00544 552 3582 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.898 0.789 – 1.02 0.101 278 2647 exclusion phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.751 0.611 – 0.924 0.0068 108 1134 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.905 0.812 – 1.01 0.0692 408 3005 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.873 0.702 – 1.09 0.223 99 955 exclusion phecode
626.8 Infertility, female Genitourinary 0.833 0.729 – 0.953 0.00771 255 2068 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.869 0.813 – 0.93 4.58e-05 1243 3886 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 0.806 0.708 – 0.917 0.00103 277 2549 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.869 0.803 – 0.94 0.000487 834 3588 exclusion phecode
627.21 Symptomatic artificial menopause Genitourinary 0.84 0.601 – 1.17 0.307 40 402 exclusion phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.782 0.638 – 0.959 0.0183 113 855 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.818 0.724 – 0.925 0.00139 314 2315 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 0.873 0.692 – 1.1 0.255 91 963 exclusion phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.925 0.756 – 1.13 0.453 118 838 exclusion phecode
628 Ovarian cyst Genitourinary 0.888 0.808 – 0.975 0.0128 539 3925 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.11 0.969 – 1.27 0.133 244 2293 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.994 0.79 – 1.25 0.959 90 772 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.989 0.682 – 1.44 0.954 30 347 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.892 0.762 – 1.04 0.156 183 1632 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.91 0.752 – 1.1 0.337 122 1112 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.877 0.7 – 1.1 0.253 88 909 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.967 0.862 – 1.08 0.568 351 2386 exclusion phecode
636.1 Threatened premature labor Pregnancy Complications 0.963 0.8 – 1.16 0.693 131 1173 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.952 0.762 – 1.19 0.665 92 869 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.902 0.753 – 1.08 0.265 132 1359 exclusion phecode
636.8 Cervical incompetence Pregnancy Complications 1.11 0.714 – 1.73 0.639 22 245 exclusion phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.45 0.938 – 2.23 0.0946 20 240 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.868 0.723 – 1.04 0.132 129 1768 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.888 0.682 – 1.16 0.379 66 885 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.04 0.811 – 1.33 0.774 71 800 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.964 0.684 – 1.36 0.835 35 368 exclusion phecode
644 Anemia during pregnancy Pregnancy Complications 1.2 0.921 – 1.56 0.178 69 747 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.05 0.914 – 1.21 0.474 227 2138 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.01 0.79 – 1.29 0.94 75 655 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.947 0.72 – 1.24 0.694 63 712 exclusion phecode
647.3 Major puerperal infection Pregnancy Complications 1.18 0.721 – 1.93 0.51 20 204 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.981 0.876 – 1.1 0.749 367 2532 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.91 0.751 – 1.1 0.335 124 1610 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.04 0.882 – 1.23 0.623 163 1713 exclusion phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.04 0.781 – 1.38 0.791 54 637 exclusion phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 0.891 0.687 – 1.16 0.384 65 637 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.938 0.851 – 1.03 0.195 514 3055 exclusion phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 0.867 0.739 – 1.02 0.0766 188 1757 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.06 0.925 – 1.21 0.411 253 2170 exclusion phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 0.997 0.486 – 2.04 0.993 5 144 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.947 0.829 – 1.08 0.419 266 2143 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.12 0.858 – 1.46 0.402 64 707 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.95 0.686 – 1.32 0.758 44 543 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.73 0.56 – 0.951 0.0198 63 580 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.16 1.1 – 1.23 4.45e-07 1331 9223 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.09 0.962 – 1.24 0.173 259 2612 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.21 1.05 – 1.39 0.0072 224 2219 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.2 1.08 – 1.34 0.000499 397 4472 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.17 1.05 – 1.29 0.00286 406 4641 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.24 1.1 – 1.38 0.00026 330 3685 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.22 1.08 – 1.37 0.0017 285 3560 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.11 1.01 – 1.22 0.0294 485 4893 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 0.973 0.802 – 1.18 0.776 114 1391 exclusion phecode
686.2 Impetigo Dermatologic 1.18 0.952 – 1.47 0.13 102 1017 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.39 0.957 – 2.01 0.0837 28 403 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.01 0.708 – 1.44 0.95 34 380 exclusion phecode
686.5 Pyoderma Dermatologic 2.17 1.06 – 4.45 0.0338 8 144 exclusion phecode
687 Symptoms affecting skin Dermatologic 0.947 0.856 – 1.05 0.295 449 3752 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.974 0.922 – 1.03 0.336 1623 8190 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.998 0.794 – 1.26 0.99 85 837 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.05 0.987 – 1.11 0.127 1359 8010 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.916 0.872 – 0.961 0.000374 2241 8716 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.897 0.841 – 0.956 0.000848 1200 6764 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.896 0.84 – 0.955 8e-04 1200 6752 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.934 0.773 – 1.13 0.485 123 1322 exclusion phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 1.48 0.907 – 2.41 0.117 21 163 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.834 0.758 – 0.918 0.000193 500 4084 exclusion phecode
694.1 Vitiligo Dermatologic 1.11 0.792 – 1.56 0.538 37 300 exclusion phecode
694.2 Other dyschromia Dermatologic 0.813 0.735 – 0.9 6.18e-05 447 3711 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 0.989 0.622 – 1.57 0.962 24 163 exclusion phecode
695 Erythematous conditions Dermatologic 0.982 0.912 – 1.06 0.633 844 6904 exclusion phecode
695.1 Toxic erythema Dermatologic 0.809 0.479 – 1.37 0.429 15 173 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.12 0.68 – 1.85 0.651 20 172 exclusion phecode
695.3 Rosacea Dermatologic 0.836 0.749 – 0.933 0.0014 366 3953 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.17 1 – 1.37 0.0468 185 1711 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.14 0.878 – 1.49 0.318 67 616 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.17 0.998 – 1.37 0.0527 177 1613 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 1.06 0.87 – 1.29 0.56 113 1324 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1.01 0.827 – 1.23 0.929 105 1866 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.823 0.504 – 1.34 0.436 15 165 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.05 0.877 – 1.25 0.617 132 1504 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.898 0.792 – 1.02 0.0948 275 3123 exclusion phecode
696.3 Pityriasis Dermatologic 0.681 0.464 – 0.999 0.0491 36 277 exclusion phecode
696.4 Psoriasis Dermatologic 0.95 0.829 – 1.09 0.466 238 2876 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.95 0.825 – 1.09 0.478 222 2603 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.857 0.624 – 1.18 0.339 41 615 exclusion phecode
697 Sarcoidosis Dermatologic 0.988 0.746 – 1.31 0.935 47 653 exclusion phecode
698 Pruritus and related conditions Dermatologic 0.946 0.865 – 1.03 0.223 557 5421 exclusion phecode
700 Corns and callosities Dermatologic 1.02 0.888 – 1.17 0.783 229 2355 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.952 0.903 – 1 0.0715 1735 9024 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 1.04 0.869 – 1.25 0.664 141 1181 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1 0.921 – 1.09 0.947 623 5144 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.936 0.778 – 1.13 0.486 133 1404 exclusion phecode
701.4 Keloid scar Dermatologic 0.861 0.727 – 1.02 0.0862 158 1531 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1.11 0.89 – 1.38 0.361 91 904 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.868 0.819 – 0.921 2.29e-06 1588 6196 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.834 0.775 – 0.897 1.14e-06 950 5238 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.875 0.821 – 0.932 3.55e-05 1277 6486 exclusion phecode
702.4 Degenerative skin disorders Dermatologic 1.04 0.684 – 1.57 0.868 25 197 exclusion phecode
703 Diseases of nail, NOS Dermatologic 0.893 0.796 – 1 0.0521 333 3307 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.906 0.773 – 1.06 0.221 167 1978 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.948 0.879 – 1.02 0.173 765 7325 exclusion phecode
704.1 Alopecia Dermatologic 0.886 0.797 – 0.984 0.0237 409 3630 exclusion phecode
704.11 Alopecia Areata Dermatologic 1.16 0.736 – 1.83 0.52 21 179 exclusion phecode
704.12 Telogen effluvium Dermatologic 0.86 0.531 – 1.39 0.542 22 160 exclusion phecode
704.2 Hirsutism Dermatologic 1.13 0.846 – 1.52 0.398 45 882 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.01 0.903 – 1.12 0.914 375 3901 exclusion phecode
705 Disorders of sweat glands Dermatologic 0.899 0.745 – 1.09 0.27 115 1541 exclusion phecode
705.1 Dyshidrosis Dermatologic 0.698 0.473 – 1.03 0.0706 33 340 exclusion phecode
705.3 Hidradenitis Dermatologic 1.11 0.808 – 1.53 0.511 33 639 exclusion phecode
705.8 Hyperhidrosis Dermatologic 0.971 0.853 – 1.11 0.656 263 2649 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 0.867 0.82 – 0.917 5.56e-07 1531 9248 exclusion phecode
706.1 Acne Dermatologic 0.833 0.774 – 0.897 1.43e-06 832 5978 exclusion phecode
706.2 Sebaceous cyst Dermatologic 0.911 0.838 – 0.99 0.0279 644 6019 exclusion phecode
706.3 Seborrhea Dermatologic 0.708 0.407 – 1.23 0.222 16 137 exclusion phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.856 0.76 – 0.963 0.00984 322 3244 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.22 1.12 – 1.33 3.87e-06 597 5738 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.29 1.11 – 1.49 0.000943 206 1652 exclusion phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.34 1.15 – 1.56 0.000195 180 1928 exclusion phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1.22 1.09 – 1.36 0.00046 356 3547 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.965 0.867 – 1.07 0.515 383 3529 exclusion phecode
709.2 Sicca syndrome Dermatologic 0.938 0.786 – 1.12 0.477 132 1192 exclusion phecode
709.3 Systemic sclerosis Dermatologic 1.03 0.81 – 1.3 0.823 72 515 exclusion phecode
709.5 Dermatomyositis Dermatologic 0.935 0.598 – 1.46 0.769 18 210 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.28 0.852 – 1.92 0.235 27 213 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.986 0.861 – 1.13 0.844 239 2277 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.29 1.14 – 1.46 5.09e-05 282 2616 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.3 1.15 – 1.48 3.44e-05 275 2462 exclusion phecode
710.11 Acute osteomyelitis Musculoskeletal 1.46 1.21 – 1.75 5.15e-05 130 1196 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.31 1.09 – 1.58 0.00446 126 1049 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.32 1.16 – 1.5 2.23e-05 258 2362 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 0.774 0.61 – 0.982 0.0348 77 883 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.04 0.771 – 1.41 0.787 46 610 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.05 0.734 – 1.5 0.79 31 400 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.1 0.845 – 1.42 0.486 62 642 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.62 1.01 – 2.61 0.0473 20 304 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.08 0.977 – 1.19 0.133 468 4438 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.12 1 – 1.24 0.0451 386 3663 exclusion phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.21 0.858 – 1.71 0.275 33 237 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.13 0.986 – 1.29 0.0803 244 2802 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.11 0.848 – 1.45 0.447 57 676 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.13 0.847 – 1.51 0.405 50 545 exclusion phecode
716 Other arthropathies Musculoskeletal 1.05 0.998 – 1.1 0.0587 2506 7939 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.735 0.508 – 1.06 0.103 33 432 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.931 0.607 – 1.43 0.743 20 272 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.05 0.999 – 1.1 0.056 2492 7936 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.966 0.713 – 1.31 0.823 52 562 exclusion phecode
720 Spinal stenosis Musculoskeletal 1.07 0.985 – 1.16 0.106 649 6151 exclusion phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1.11 1 – 1.22 0.0509 428 4881 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1.05 0.986 – 1.13 0.122 1075 7226 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.05 0.982 – 1.12 0.154 1008 7068 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.09 0.92 – 1.29 0.322 152 1737 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 1.09 0.79 – 1.52 0.587 40 562 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.07 1 – 1.14 0.0428 1199 8037 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.06 0.981 – 1.15 0.133 659 7186 exclusion phecode
722.3 Schmorl's nodes Musculoskeletal 1.05 0.731 – 1.5 0.804 32 264 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.09 1.01 – 1.17 0.0369 752 6798 exclusion phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.07 0.858 – 1.34 0.539 92 1084 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.12 0.877 – 1.42 0.37 73 827 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.963 0.863 – 1.08 0.506 370 4256 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.05 0.912 – 1.2 0.51 230 2233 exclusion phecode
723.1 Torticollis Musculoskeletal 0.963 0.744 – 1.25 0.777 62 589 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.04 0.97 – 1.12 0.267 890 7601 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1.02 0.926 – 1.11 0.748 520 5376 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.981 0.795 – 1.21 0.859 98 1021 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.11 0.954 – 1.3 0.173 175 2182 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.08 0.958 – 1.22 0.2 288 3198 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.927 0.882 – 0.975 0.00315 2111 7342 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.93 0.88 – 0.984 0.0113 1605 7313 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.906 0.775 – 1.06 0.217 173 2098 exclusion phecode
726.3 Bursitis Musculoskeletal 0.832 0.745 – 0.929 0.00113 359 3818 exclusion phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.837 0.73 – 0.96 0.011 228 2653 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.939 0.888 – 0.993 0.0271 1618 7309 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.938 0.865 – 1.02 0.128 681 6062 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.936 0.742 – 1.18 0.576 80 907 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.932 0.833 – 1.04 0.226 347 3217 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.966 0.775 – 1.2 0.757 89 1092 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.927 0.838 – 1.03 0.146 420 4585 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.05 0.891 – 1.23 0.571 167 1482 exclusion phecode
727.8 Plica syndrome Musculoskeletal 0.953 0.703 – 1.29 0.757 50 385 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.951 0.889 – 1.02 0.151 988 7020 exclusion phecode
728.1 Muscular calcification and ossification Musculoskeletal 1.15 0.761 – 1.75 0.503 22 186 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.05 0.838 – 1.3 0.691 77 712 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.821 0.746 – 0.903 4.92e-05 473 5331 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.663 0.538 – 0.817 0.000111 108 781 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.08 0.998 – 1.17 0.0569 669 6222 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.64 1 – 2.67 0.049 19 168 exclusion phecode
729.3 Panniculitis Musculoskeletal 1.03 0.576 – 1.84 0.923 9 304 exclusion phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 1.31 0.801 – 2.14 0.282 21 155 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.63 1.14 – 2.34 0.00758 36 353 exclusion phecode
732 Osteochondropathies Musculoskeletal 1.04 0.829 – 1.3 0.745 91 1000 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.08 0.773 – 1.52 0.638 40 530 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.25 0.813 – 1.92 0.309 24 265 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.94 0.882 – 1 0.0599 1259 6039 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.1 0.824 – 1.46 0.526 53 452 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.25 1.05 – 1.48 0.0101 160 1061 exclusion phecode
733.6 Costochondritis Musculoskeletal 0.864 0.684 – 1.09 0.223 79 878 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.21 1.05 – 1.4 0.00931 207 1900 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.01 0.692 – 1.48 0.95 33 261 exclusion phecode
735 Acquired foot deformities Musculoskeletal 0.955 0.884 – 1.03 0.241 762 6663 exclusion phecode
735.1 Flat foot Musculoskeletal 0.878 0.718 – 1.07 0.206 109 1399 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 0.976 0.858 – 1.11 0.716 279 2535 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.12 0.943 – 1.33 0.199 160 1562 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.926 0.747 – 1.15 0.486 103 848 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.862 0.769 – 0.965 0.0103 348 3312 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 0.95 0.872 – 1.03 0.234 614 6048 exclusion phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.951 0.661 – 1.37 0.786 32 220 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.03 0.786 – 1.34 0.846 66 463 exclusion phecode
736.3 Acquired deformities of hip Musculoskeletal 0.958 0.555 – 1.65 0.878 16 188 exclusion phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 1.01 0.748 – 1.35 0.971 48 682 exclusion phecode
736.5 Acquired deformities of knee Musculoskeletal 0.905 0.64 – 1.28 0.57 32 499 exclusion phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.903 0.714 – 1.14 0.396 78 779 exclusion phecode
737 Curvature of spine Musculoskeletal 1.02 0.923 – 1.13 0.708 462 3890 exclusion phecode
737.1 Kyphosis (acquired) Musculoskeletal 1.1 0.899 – 1.34 0.356 110 1080 exclusion phecode
737.2 Lordosis (acquired) Musculoskeletal 2.59 1.31 – 5.11 0.00608 12 152 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.979 0.878 – 1.09 0.7 386 3060 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.14 1.05 – 1.24 0.00219 631 5535 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.15 0.993 – 1.34 0.0618 198 2157 exclusion phecode
739 Contracture of joint Musculoskeletal 1.01 0.853 – 1.19 0.938 160 1370 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.03 0.986 – 1.08 0.177 2937 7929 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.952 0.891 – 1.02 0.145 1157 6673 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.932 0.869 – 1 0.0511 1023 6187 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.07 0.888 – 1.28 0.483 122 1668 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.01 0.889 – 1.14 0.916 306 2887 exclusion phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 1.13 0.885 – 1.45 0.322 71 857 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.04 0.99 – 1.09 0.119 2783 7867 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.999 0.949 – 1.05 0.955 1879 8544 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.757 0.571 – 1 0.0521 54 599 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 0.971 0.864 – 1.09 0.619 323 2891 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 1.11 1.01 – 1.22 0.0272 496 4936 exclusion phecode
741.4 Joint effusions Musculoskeletal 0.945 0.864 – 1.03 0.214 540 5845 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.05 0.669 – 1.64 0.838 18 199 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.836 0.437 – 1.6 0.587 11 169 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.01 0.944 – 1.08 0.804 1043 8142 exclusion phecode
742.1 Loose body in joint Musculoskeletal 0.946 0.665 – 1.35 0.759 28 422 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.863 0.693 – 1.08 0.189 85 933 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.21 0.932 – 1.57 0.154 62 634 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 1.01 0.94 – 1.08 0.873 985 8034 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.992 0.945 – 1.04 0.752 2537 8248 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.01 0.943 – 1.08 0.765 1230 3995 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.01 0.939 – 1.08 0.851 1217 3952 exclusion phecode
743.12 Senile osteoporosis Musculoskeletal 0.938 0.819 – 1.08 0.359 292 1134 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1.17 0.94 – 1.45 0.16 109 601 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.08 0.958 – 1.22 0.206 326 2028 exclusion phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 1.13 0.94 – 1.36 0.194 131 862 exclusion phecode
743.22 Pathologic fracture of femur Musculoskeletal 1.54 1.1 – 2.17 0.0131 43 267 exclusion phecode
743.4 Stress fracture Musculoskeletal 0.827 0.678 – 1.01 0.0628 120 924 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.975 0.923 – 1.03 0.358 1853 7744 exclusion phecode
745 Pain in joint Musculoskeletal 0.957 0.92 – 0.995 0.0254 4517 6498 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.04 0.952 – 1.14 0.371 525 4965 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.1 0.994 – 1.23 0.0637 389 3920 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.97 0.828 – 1.14 0.71 170 1512 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.16 0.96 – 1.39 0.126 128 1550 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.21 0.976 – 1.5 0.0816 88 884 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.948 0.797 – 1.13 0.543 140 1163 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.21 0.829 – 1.75 0.327 29 272 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.901 0.776 – 1.05 0.171 206 1544 exclusion phecode
749.1 Cleft palate Congenital Anomalies 0.888 0.648 – 1.22 0.462 43 310 exclusion phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.95 0.697 – 1.3 0.748 46 303 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 1.11 0.978 – 1.27 0.105 261 2050 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.908 0.728 – 1.13 0.39 88 858 exclusion phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.723 0.484 – 1.08 0.112 29 248 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.946 0.629 – 1.42 0.789 24 258 exclusion phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 0.929 0.674 – 1.28 0.653 39 269 exclusion phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 1.14 0.569 – 2.28 0.716 11 122 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.16 0.989 – 1.36 0.0674 176 1251 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.21 0.987 – 1.47 0.0672 110 720 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.13 0.859 – 1.47 0.39 69 509 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.01 0.922 – 1.11 0.81 518 4659 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.05 0.892 – 1.24 0.541 161 1548 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.15 0.943 – 1.4 0.168 116 1100 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.846 0.601 – 1.19 0.337 38 353 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.942 0.84 – 1.06 0.307 332 3026 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.9 0.783 – 1.03 0.137 227 2060 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.942 0.744 – 1.19 0.616 74 675 exclusion phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.39 1.06 – 1.82 0.0189 62 532 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 1 0.87 – 1.15 0.982 227 2647 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.09 0.93 – 1.28 0.289 177 2072 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.796 0.591 – 1.07 0.134 42 500 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.764 0.576 – 1.01 0.0615 58 599 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.16 0.867 – 1.55 0.318 52 476 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.836 0.512 – 1.36 0.474 14 150 exclusion phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 0.93 0.553 – 1.56 0.784 14 144 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.11 0.967 – 1.27 0.14 247 2582 exclusion phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 0.757 0.501 – 1.14 0.187 27 305 exclusion phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 1.15 0.942 – 1.41 0.169 109 1222 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.06 0.905 – 1.25 0.457 175 1999 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.938 0.747 – 1.18 0.586 78 912 exclusion phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 1.13 0.69 – 1.86 0.622 18 180 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.19 0.938 – 1.51 0.151 84 961 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.13 0.835 – 1.53 0.427 50 565 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.975 0.872 – 1.09 0.659 354 3352 exclusion phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.697 0.437 – 1.11 0.128 21 172 exclusion phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 1.16 0.838 – 1.59 0.378 49 237 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.826 0.639 – 1.07 0.146 62 840 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.99 0.864 – 1.13 0.884 229 2290 exclusion phecode
757 Congenital anomalies of the integument Congenital Anomalies 0.953 0.774 – 1.17 0.653 103 926 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1 0.75 – 1.33 0.998 58 491 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.944 0.667 – 1.34 0.745 38 363 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.02 0.87 – 1.2 0.789 160 1493 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.915 0.557 – 1.5 0.726 14 188 exclusion phecode
760 Back pain Symptoms 1.08 1.03 – 1.12 0.000394 3440 7569 exclusion phecode
761 Cervicalgia Symptoms 1.02 0.969 – 1.08 0.399 1576 9228 exclusion phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 1.03 0.944 – 1.11 0.554 662 7263 exclusion phecode
764 Sciatica Symptoms 1.07 0.981 – 1.16 0.128 611 7266 exclusion phecode
765 Cervical radiculitis Symptoms 1.05 0.941 – 1.17 0.388 371 3862 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.08 1.01 – 1.15 0.0296 1017 8661 exclusion phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.14 0.758 – 1.71 0.536 28 264 exclusion phecode
769 Nonallopathic lesions NEC Symptoms 1.03 0.908 – 1.17 0.646 292 2634 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.03 0.971 – 1.1 0.306 1254 8242 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.09 1.02 – 1.17 0.0109 1015 8355 exclusion phecode
771.1 Swelling of limb Symptoms 1.09 1.02 – 1.16 0.0115 1061 8316 exclusion phecode
771.2 Cramp of limb Symptoms 1.02 0.892 – 1.17 0.761 233 2375 exclusion phecode
772 Symptoms of the muscles Symptoms 0.959 0.873 – 1.05 0.373 507 4726 exclusion phecode
772.1 Muscular wasting and disuse atrophy Symptoms 1.09 0.896 – 1.32 0.399 123 1091 exclusion phecode
772.2 Spasm of muscle Symptoms 0.956 0.874 – 1.05 0.326 542 5508 exclusion phecode
772.3 Muscle weakness Symptoms 1.05 0.966 – 1.14 0.249 640 6137 exclusion phecode
772.4 Rhabdomyolysis Symptoms 1.39 0.982 – 1.98 0.0632 38 338 exclusion phecode
772.6 Facial weakness Symptoms 1.03 0.831 – 1.27 0.794 96 1027 exclusion phecode
780 Hypothermia/Chills Symptoms 1.01 0.829 – 1.24 0.887 104 987 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.995 0.911 – 1.09 0.908 574 5709 exclusion phecode
781.1 Loss of height Symptoms 1.18 0.817 – 1.7 0.38 35 214 exclusion phecode
781.2 Abnormal posture Symptoms 0.95 0.558 – 1.62 0.852 14 123 exclusion phecode
782.3 Edema Symptoms 1.21 1.13 – 1.3 2.89e-08 976 8470 exclusion phecode
782.6 Pallor and flushing Symptoms 0.881 0.768 – 1.01 0.0673 245 2410 exclusion phecode
783 Fever of unknown origin Symptoms 1.13 1.07 – 1.2 2.41e-05 1350 9562 exclusion phecode
783.1 Postprocedural fever Symptoms 1.22 0.932 – 1.59 0.15 58 642 exclusion phecode
785 Abdominal pain Symptoms 1.06 1.02 – 1.1 0.0044 3950 7061 exclusion phecode
788 Syncope and collapse Symptoms 1.05 0.977 – 1.13 0.186 887 8223 exclusion phecode
789 Nausea and vomiting Symptoms 1.07 1.03 – 1.12 0.00215 2685 8302 exclusion phecode
789.1 Persistent vomiting Symptoms 1.26 1.09 – 1.45 0.00207 203 1910 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.1 1 – 1.21 0.0458 499 4987 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.08 0.797 – 1.45 0.63 42 564 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.09 1.03 – 1.16 0.00326 1441 9098 exclusion phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.09 0.807 – 1.46 0.582 46 771 exclusion phecode
790.9 Abnormal arterial blood gases Symptoms 1.28 0.874 – 1.87 0.207 27 339 exclusion phecode
791 Gangrene Symptoms 1.31 1.04 – 1.65 0.0212 77 589 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 0.969 0.899 – 1.04 0.406 885 4183 exclusion phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 1.02 0.911 – 1.14 0.756 370 2793 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.944 0.762 – 1.17 0.598 96 1118 exclusion phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 1.03 0.95 – 1.13 0.431 639 5303 exclusion phecode
795.8 Abnormal tumor markers Symptoms 0.906 0.801 – 1.02 0.115 295 2567 exclusion phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 1.02 0.527 – 1.96 0.96 11 129 exclusion phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 1 0.755 – 1.33 0.992 59 490 exclusion phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.803 0.706 – 0.913 0.000819 314 1514 exclusion phecode
797 Shock Symptoms 1.16 0.952 – 1.4 0.142 129 1151 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.25 0.936 – 1.67 0.13 54 436 exclusion phecode
798 Malaise and fatigue Symptoms 1.06 1.01 – 1.11 0.0108 2655 8349 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1.04 0.934 – 1.16 0.477 383 4177 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.02 0.939 – 1.12 0.59 595 5364 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.14 0.96 – 1.35 0.137 151 1086 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.11 0.956 – 1.29 0.171 192 1460 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.04 0.906 – 1.2 0.556 221 2131 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.9 0.735 – 1.1 0.309 105 871 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1 0.918 – 1.1 0.924 536 5414 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.04 0.915 – 1.19 0.526 249 2719 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.09 0.902 – 1.33 0.363 123 885 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.991 0.91 – 1.08 0.83 608 4860 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1.21 1.03 – 1.41 0.0175 177 1770 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.941 0.842 – 1.05 0.281 360 2789 exclusion phecode
803.21 Colles' fracture Injuries & Poisonings 0.934 0.753 – 1.16 0.535 93 688 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.02 0.87 – 1.19 0.833 176 1228 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.956 0.87 – 1.05 0.351 491 3985 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.03 0.922 – 1.16 0.582 347 2856 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.16 0.996 – 1.36 0.0565 177 1371 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.01 0.939 – 1.09 0.785 829 6736 exclusion phecode
816 Cerebral laceration and contusion Injuries & Poisonings 1.33 0.76 – 2.32 0.318 16 101 exclusion phecode
817 Concussion Injuries & Poisonings 1.03 0.903 – 1.17 0.686 258 2679 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.25 0.999 – 1.55 0.0512 85 688 exclusion phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 1.44 0.929 – 2.24 0.103 24 189 exclusion phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.34 0.84 – 2.15 0.218 24 203 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.03 0.948 – 1.12 0.472 607 5516 exclusion phecode
830 Dislocation Injuries & Poisonings 0.919 0.856 – 0.988 0.0213 868 8371 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.886 0.804 – 0.975 0.0136 465 5322 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 1 0.794 – 1.27 0.979 80 1028 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.907 0.861 – 0.955 0.000243 1782 9030 exclusion phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.941 0.751 – 1.18 0.597 82 1115 exclusion phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.912 0.8 – 1.04 0.17 253 3256 exclusion phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.852 0.788 – 0.921 5.85e-05 746 6296 exclusion phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.959 0.855 – 1.07 0.472 339 3848 exclusion phecode
842 Other sprains and strains Injuries & Poisonings 0.907 0.811 – 1.02 0.0914 334 3490 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.15 1.05 – 1.27 0.0035 461 4470 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.25 1.15 – 1.35 5.77e-08 669 5863 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.59 1.29 – 1.95 8.94e-06 107 959 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.27 1.14 – 1.41 5.57e-06 412 4147 exclusion phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.14 0.867 – 1.5 0.346 54 619 exclusion phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.21 0.916 – 1.61 0.176 59 578 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.1 0.97 – 1.25 0.136 269 3092 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.15 1.05 – 1.26 0.00288 517 5130 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.2 1.09 – 1.31 7.13e-05 567 4779 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.28 0.913 – 1.8 0.151 40 366 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.08 1.01 – 1.15 0.0329 997 8403 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.25 0.936 – 1.66 0.131 55 444 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1.01 0.743 – 1.37 0.948 41 324 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.983 0.885 – 1.09 0.758 392 3010 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.08 0.831 – 1.41 0.555 60 476 exclusion phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 1.13 0.903 – 1.42 0.283 93 604 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 1.16 0.883 – 1.52 0.289 64 395 exclusion phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.1 0.795 – 1.54 0.554 38 391 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.07 0.998 – 1.16 0.0566 808 7420 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.994 0.828 – 1.19 0.951 128 1282 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.915 0.798 – 1.05 0.2 233 2284 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.38 1.11 – 1.73 0.0045 85 951 exclusion phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.27 0.925 – 1.73 0.141 44 583 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.18 0.979 – 1.42 0.0834 109 1075 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.48 1.06 – 2.07 0.0217 34 304 exclusion phecode
875 Non-healing surgical wound Injuries & Poisonings 1.23 1.03 – 1.47 0.0251 127 1275 exclusion phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.15 0.97 – 1.35 0.109 148 1736 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.08 0.948 – 1.24 0.239 237 2291 exclusion phecode
910 Superficial injury, infected Injuries & Poisonings 1.05 0.669 – 1.66 0.822 22 268 exclusion phecode
911 Blister Injuries & Poisonings 1.01 0.769 – 1.33 0.939 50 571 exclusion phecode
912 Insect bite Injuries & Poisonings 0.916 0.756 – 1.11 0.375 112 1187 exclusion phecode
913 Toxic effect of venom Injuries & Poisonings 0.775 0.624 – 0.963 0.0213 85 744 exclusion phecode
916 Contusion Injuries & Poisonings 1.04 0.97 – 1.11 0.289 987 8993 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 1.08 0.921 – 1.26 0.35 184 2047 exclusion phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.879 0.737 – 1.05 0.149 149 1629 exclusion phecode
938 Dermatitis due to solar radiation Dermatologic 0.879 0.826 – 0.935 4.21e-05 1328 6321 exclusion phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.964 0.711 – 1.31 0.812 48 508 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.869 0.816 – 0.926 1.43e-05 1269 6176 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.948 0.895 – 1 0.0692 1492 7699 exclusion phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 1.38 0.909 – 2.11 0.13 28 224 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1 0.72 – 1.4 0.977 37 380 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.39 1.07 – 1.8 0.0136 76 617 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.913 0.757 – 1.1 0.338 125 1147 exclusion phecode
947 Urticaria Dermatologic 0.955 0.844 – 1.08 0.468 287 2944 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.02 0.969 – 1.08 0.4 1617 7675 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.06 0.867 – 1.29 0.582 107 1049 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.627 0.427 – 0.922 0.0176 34 324 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.06 0.943 – 1.2 0.321 305 2721 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 0.877 0.612 – 1.26 0.474 38 329 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.923 0.624 – 1.37 0.69 34 249 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.2 1.1 – 1.31 7.63e-05 552 5167 exclusion phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 0.941 0.75 – 1.18 0.597 88 767 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.23 1.1 – 1.37 4e-04 342 3712 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.25 1.04 – 1.49 0.0164 138 1185 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.13 0.983 – 1.29 0.0872 233 2385 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.14 0.971 – 1.33 0.11 172 1659 exclusion phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.13 0.904 – 1.41 0.285 84 794 exclusion phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 2.12 1.04 – 4.35 0.0394 11 118 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.1 0.888 – 1.36 0.388 99 974 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.13 1.04 – 1.23 0.00324 662 5444 exclusion phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.15 1.06 – 1.25 0.00113 644 5337 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.21 1.01 – 1.46 0.0394 129 1472 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.21 1 – 1.47 0.05 120 1391 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.11 0.953 – 1.29 0.182 199 2115 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.31 1.16 – 1.47 1.1e-05 303 3397 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.92 0.614 – 1.38 0.685 27 247 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.31 0.889 – 1.93 0.172 28 229 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.13 0.998 – 1.27 0.0533 305 2905 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.47 1.15 – 1.89 0.00236 74 697 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.49 0.878 – 2.53 0.14 18 124 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.51 1.13 – 2.02 0.00566 51 576 exclusion phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 1.32 0.815 – 2.15 0.258 13 157 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.78 1.07 – 2.96 0.0254 16 198 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.28 0.819 – 2.01 0.276 21 234 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.873 0.502 – 1.52 0.631 14 199 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.847 0.502 – 1.43 0.535 15 160 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.16 1.04 – 1.29 0.0085 383 3849 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.15 1.06 – 1.24 0.000397 797 7171 exclusion phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 1.09 0.967 – 1.24 0.154 288 2809 exclusion phecode
985 Toxic effect of other metals Injuries & Poisonings 2.03 1.09 – 3.79 0.0264 17 92 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.32 0.937 – 1.86 0.112 34 302 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.09 1.01 – 1.16 0.0202 954 6503 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.26 1.14 – 1.38 5.35e-06 461 4485 exclusion phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.28 0.984 – 1.66 0.0658 74 650 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.23 1.11 – 1.36 4.71e-05 429 4266 exclusion phecode
994.21 Septic shock Injuries & Poisonings 1.31 1.09 – 1.58 0.00341 138 1270 exclusion phecode
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