Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Body mass index Michigan Genomics Initiative Freeze 3 (MGI) PheWAS analysis

Body mass index — Michigan Genomics Initiative Freeze 3 (MGI) PRS PheWAS

PRS model
PRS ID exprsweb-bmi-23104-irnt-plink-mgi-freeze3-20211120Legacy PLINKC+T (GT)UK Biobank GWAS

Evaluation cohort: Michigan Genomics Initiative Freeze 3 (MGI).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: normal-range subset (18.5-24.9).

For this ExPRS, the exclusion sensitivity scan keeps only the study's normal-range subset for Body mass index (18.5-24.9) before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.

680 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.03 0.987 – 1.07 0.191 3004 29292 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.1 1.03 – 1.17 0.00213 1322 13162 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.09 1.02 – 1.17 0.00999 1046 10455 all phecode
008.6 Viral Enteritis Infectious Diseases 1.09 1.01 – 1.18 0.0224 770 7676 all phecode
010 Tuberculosis Infectious Diseases 1.06 0.924 – 1.22 0.396 244 2425 all phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.977 0.78 – 1.22 0.843 86 855 all phecode
038 Septicemia Infectious Diseases 1.12 1.07 – 1.16 4.5e-07 2582 24779 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.13 1.03 – 1.24 0.00862 568 5629 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.2 1.04 – 1.38 0.0103 235 2350 all phecode
038.3 Bacteremia Infectious Diseases 1.14 1.07 – 1.22 2.92e-05 1210 12079 all phecode
041 Bacterial infection NOS Infectious Diseases 1.08 1.05 – 1.12 5.57e-08 5750 38799 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.16 1.1 – 1.22 1.42e-08 1707 16977 all phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.19 1.11 – 1.28 1.45e-06 920 9192 all phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.21 1.12 – 1.31 8.15e-07 783 7812 all phecode
041.2 Streptococcus infection Infectious Diseases 1.09 1.03 – 1.15 0.00135 1632 16287 all phecode
041.21 Rheumatic fever / chorea Infectious Diseases 0.963 0.844 – 1.1 0.577 257 2554 all phecode
041.4 E. coli Infectious Diseases 1.1 1.04 – 1.18 0.00223 1175 11680 all phecode
041.8 H. pylori Infectious Diseases 1.04 0.913 – 1.2 0.528 257 2521 all phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.17 1.05 – 1.3 0.00571 387 3864 all phecode
053 Herpes zoster Infectious Diseases 0.944 0.894 – 0.998 0.0411 1560 15184 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.913 0.788 – 1.06 0.223 220 2169 all phecode
054 Herpes simplex Infectious Diseases 0.959 0.908 – 1.01 0.133 1593 15600 all phecode
070 Viral hepatitis Infectious Diseases 1.1 1.02 – 1.18 0.0166 829 8280 all phecode
070.1 Viral hepatitis A Infectious Diseases 1.15 0.903 – 1.46 0.262 87 860 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.15 0.993 – 1.34 0.0609 215 2138 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.1 1 – 1.21 0.0487 528 5280 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.08 0.922 – 1.27 0.34 197 1964 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.03 0.968 – 1.1 0.345 1145 11381 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.1 0.929 – 1.3 0.271 145 1450 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.04 0.864 – 1.25 0.672 117 1163 all phecode
078 Viral warts & HPV Infectious Diseases 0.909 0.876 – 0.943 4.8e-07 3434 29624 all phecode
079 Viral infection Infectious Diseases 0.957 0.931 – 0.984 0.00189 6664 35342 all phecode
079.1 Varicella infection Infectious Diseases 0.904 0.872 – 0.936 2.29e-08 3793 31251 all phecode
079.2 Infectious mononucleosis Infectious Diseases 0.892 0.785 – 1.01 0.0813 283 2723 all phecode
079.9 Viremia, NOS Infectious Diseases 1.07 0.993 – 1.15 0.0752 838 8253 all phecode
080 Postoperative infection Infectious Diseases 1.16 1.11 – 1.21 5.06e-12 2619 26065 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.14 1.08 – 1.2 3.34e-06 1589 15884 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.998 0.932 – 1.07 0.963 965 9630 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.02 0.984 – 1.06 0.279 3544 30054 all phecode
110.1 Dermatophytosis Infectious Diseases 1.03 0.989 – 1.07 0.163 3241 27244 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.04 0.994 – 1.1 0.084 2044 16765 all phecode
110.12 Althete's foot Infectious Diseases 1.05 0.973 – 1.13 0.222 899 8043 all phecode
110.13 Dermatophytosis of the body Infectious Diseases 1.08 0.997 – 1.16 0.0581 790 7827 all phecode
110.2 Dermatomycoses Infectious Diseases 0.982 0.883 – 1.09 0.744 398 3971 all phecode
112 Candidiasis Infectious Diseases 1.09 1.05 – 1.13 3.34e-06 3685 30495 all phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.25 1.15 – 1.35 2.41e-07 682 6732 all phecode
117 Mycoses Infectious Diseases 1.02 0.936 – 1.11 0.647 608 6069 all phecode
117.1 Histoplasmosis Infectious Diseases 1.22 0.964 – 1.54 0.0987 81 801 all phecode
117.4 Aspergillosis Infectious Diseases 1.04 0.873 – 1.25 0.641 140 1387 all phecode
130 Spirochetal infection Infectious Diseases 0.896 0.763 – 1.05 0.18 168 1677 all phecode
130.1 Lyme disease Infectious Diseases 0.877 0.724 – 1.06 0.179 116 1160 all phecode
131 Protozoan infection Infectious Diseases 1.29 1 – 1.67 0.0502 61 610 all phecode
132 Infestation (lice, mites) Infectious Diseases 1.04 0.899 – 1.21 0.582 195 1948 all phecode
134 Helminthiases Infectious Diseases 1.03 0.813 – 1.29 0.834 83 812 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.16 0.866 – 1.55 0.321 53 513 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.04 0.998 – 1.08 0.0639 3279 32486 all phecode
145 Cancer of mouth Neoplasms 1.05 0.992 – 1.11 0.0961 1481 14725 all phecode
145.1 Cancer of lip Neoplasms 1.13 0.886 – 1.43 0.332 76 750 all phecode
145.2 Cancer of tongue Neoplasms 1.05 0.961 – 1.14 0.302 645 6430 all phecode
145.3 Cancer of major salivary glands Neoplasms 0.964 0.862 – 1.08 0.524 361 3597 all phecode
145.4 Cancer of the gums Neoplasms 1 0.847 – 1.19 0.957 166 1632 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.01 0.872 – 1.18 0.86 206 2048 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.03 0.975 – 1.1 0.267 1290 12873 all phecode
149.1 Cancer of oropharynx Neoplasms 1.04 0.929 – 1.17 0.488 350 3499 all phecode
149.2 Cancer of nasopharynx Neoplasms 1.12 0.908 – 1.37 0.295 100 1000 all phecode
149.3 Cancer of hypopharynx Neoplasms 0.991 0.776 – 1.27 0.942 82 819 all phecode
149.4 Cancer of larynx Neoplasms 1.12 1.01 – 1.25 0.04 386 3857 all phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 1.06 0.965 – 1.16 0.235 552 5505 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.925 0.806 – 1.06 0.266 240 2398 all phecode
150 Cancer of esophagus Neoplasms 1.23 1.11 – 1.36 5.01e-05 433 4315 all phecode
151 Cancer of stomach Neoplasms 1.08 0.982 – 1.19 0.11 498 4962 all phecode
153 Colorectal cancer Neoplasms 0.992 0.937 – 1.05 0.773 1458 14383 all phecode
153.2 Colon cancer Neoplasms 1.01 0.951 – 1.08 0.668 1160 11472 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.966 0.895 – 1.04 0.37 815 8093 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.05 0.953 – 1.15 0.333 511 5097 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.06 0.945 – 1.19 0.318 344 3433 all phecode
157 Pancreatic cancer Neoplasms 0.973 0.884 – 1.07 0.575 503 5005 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1 0.951 – 1.06 0.889 1623 15759 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.03 0.976 – 1.08 0.305 1818 17869 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.05 0.905 – 1.21 0.54 221 2206 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.02 0.867 – 1.21 0.776 158 1578 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.04 0.917 – 1.18 0.527 293 2920 all phecode
164 Cancer of intrathoracic organs Neoplasms 0.992 0.826 – 1.19 0.934 133 1324 all phecode
165 Cancer within the respiratory system Neoplasms 1.05 0.987 – 1.11 0.13 1336 13340 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.04 0.97 – 1.11 0.285 1057 10552 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.992 0.943 – 1.04 0.749 1792 17850 all phecode
170.1 Bone cancer Neoplasms 0.985 0.911 – 1.06 0.692 773 7690 all phecode
170.2 Cancer of connective tissue Neoplasms 0.989 0.931 – 1.05 0.712 1266 12632 all phecode
172 Skin cancer Neoplasms 0.943 0.919 – 0.968 9.05e-06 8608 33186 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.92 0.892 – 0.95 2.01e-07 5330 30106 all phecode
172.11 Melanomas of skin Neoplasms 0.917 0.882 – 0.954 1.49e-05 3100 25064 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.94 0.914 – 0.967 1.58e-05 7095 30462 all phecode
172.21 Basal cell carcinoma Neoplasms 0.915 0.882 – 0.95 2.86e-06 3690 23868 all phecode
172.22 Squamous cell carcinoma Neoplasms 0.971 0.929 – 1.02 0.201 2414 17683 all phecode
172.3 Carcinoma in situ of skin Neoplasms 0.893 0.844 – 0.945 9.84e-05 1482 12326 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.919 0.875 – 0.965 0.000648 1997 18755 all phecode
174 Breast cancer Neoplasms 0.935 0.898 – 0.974 0.0014 3186 15514 all phecode
174.1 Breast cancer [female] Neoplasms 0.933 0.894 – 0.973 0.00114 3036 14701 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.934 0.895 – 0.974 0.00155 2991 14639 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.82 0.711 – 0.946 0.00652 233 2307 all phecode
175 Acquired absence of breast Neoplasms 0.975 0.907 – 1.05 0.5 919 8920 all phecode
180 Cervical cancer and dysplasia Neoplasms 1.01 0.95 – 1.07 0.833 1431 12185 all phecode
180.1 Cervical cancer Neoplasms 1.09 0.989 – 1.2 0.0824 500 4982 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.961 0.9 – 1.03 0.245 1048 9323 all phecode
182 Malignant neoplasm of uterus Neoplasms 1.12 1.04 – 1.21 0.00419 765 7613 all phecode
184 Cancer of other female genital organs Neoplasms 0.996 0.935 – 1.06 0.9 1191 11592 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.981 0.895 – 1.08 0.685 573 5719 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.924 0.832 – 1.03 0.138 432 4309 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.05 0.959 – 1.14 0.301 608 6057 all phecode
185 Cancer of prostate Neoplasms 0.935 0.894 – 0.978 0.00339 2901 10342 all phecode
187 Cancer of other male genital organs Neoplasms 0.99 0.882 – 1.11 0.87 339 3384 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.12 0.914 – 1.37 0.276 115 1141 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.949 0.812 – 1.11 0.51 183 1830 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.943 0.711 – 1.25 0.682 57 562 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.08 1.04 – 1.12 0.00022 2923 23541 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.09 1.03 – 1.15 0.00402 1450 14437 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.11 1.05 – 1.18 0.000654 1267 12655 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.06 0.923 – 1.23 0.391 237 2347 all phecode
189.2 Cancer of bladder Neoplasms 1.08 1.02 – 1.13 0.00544 1783 15224 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.07 1.01 – 1.13 0.0136 1657 14178 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.04 0.96 – 1.13 0.319 678 6586 all phecode
190 Cancer of eye Neoplasms 0.935 0.779 – 1.12 0.466 138 1374 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.999 0.937 – 1.07 0.984 1078 10771 all phecode
191.1 Cancer of brain and nervous system Neoplasms 0.979 0.904 – 1.06 0.611 706 7052 all phecode
191.11 Cancer of brain Neoplasms 0.952 0.873 – 1.04 0.273 600 5996 all phecode
193 Thyroid cancer Neoplasms 1.03 0.96 – 1.1 0.422 945 9393 all phecode
194 Cancer of other endocrine glands Neoplasms 1.03 0.946 – 1.13 0.465 579 5759 all phecode
195 Cancer, suspected or other Neoplasms 1.01 0.985 – 1.03 0.554 16962 26401 all phecode
195.1 Malignant neoplasm, other Neoplasms 1 0.981 – 1.02 0.795 16670 26384 all phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1.03 0.97 – 1.1 0.3 1103 9766 all phecode
196 Radiotherapy Neoplasms 0.924 0.883 – 0.966 0.000545 2427 17006 all phecode
197 Chemotherapy Neoplasms 1.01 0.982 – 1.05 0.399 4952 23797 all phecode
198 Secondary malignant neoplasm Neoplasms 1.02 0.984 – 1.05 0.333 5801 23481 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.999 0.963 – 1.04 0.977 3677 21489 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.07 1 – 1.14 0.0386 1072 10334 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.04 0.966 – 1.12 0.3 866 8538 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.05 0.971 – 1.13 0.22 767 7558 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.988 0.907 – 1.08 0.78 640 6338 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.01 0.942 – 1.09 0.717 866 8307 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.958 0.853 – 1.08 0.474 336 3253 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.01 0.981 – 1.04 0.472 5693 25767 all phecode
199.4 Neurofibromatosis Neoplasms 1.01 0.814 – 1.27 0.895 88 880 all phecode
200 Myeloproliferative disease Neoplasms 1.06 0.99 – 1.13 0.095 1113 11098 all phecode
200.1 Polycythemia vera Neoplasms 1.21 1.05 – 1.39 0.00982 231 2310 all phecode
201 Hodgkin's disease Neoplasms 1.13 0.958 – 1.33 0.149 172 1705 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.01 0.959 – 1.07 0.634 1559 15571 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.01 0.953 – 1.07 0.715 1329 13268 all phecode
202.21 Nodular lymphoma Neoplasms 0.955 0.88 – 1.04 0.27 693 6923 all phecode
202.22 Reticulosarcoma Neoplasms 1.22 1.03 – 1.43 0.0205 170 1693 all phecode
202.24 Large cell lymphoma Neoplasms 1.09 0.918 – 1.29 0.326 160 1586 all phecode
204 Leukemia Neoplasms 1.06 0.98 – 1.16 0.138 689 6876 all phecode
204.1 Lymphoid leukemia Neoplasms 0.898 0.779 – 1.04 0.137 236 2354 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.859 0.672 – 1.1 0.224 74 734 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.874 0.739 – 1.03 0.118 173 1724 all phecode
204.2 Myeloid leukemia Neoplasms 1.07 0.935 – 1.22 0.329 265 2633 all phecode
204.21 Myeloid leukemia, acute Neoplasms 1.12 0.94 – 1.34 0.2 153 1516 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.08 0.809 – 1.45 0.59 61 610 all phecode
204.4 Multiple myeloma Neoplasms 1.23 1.06 – 1.42 0.00502 217 2162 all phecode
208 Benign neoplasm of colon Neoplasms 0.981 0.958 – 1 0.108 10303 34953 all phecode
209 Neuroendocrine tumors Neoplasms 0.995 0.87 – 1.14 0.945 258 2580 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.997 0.949 – 1.05 0.916 1891 18839 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.08 1.05 – 1.11 2.84e-08 7329 36606 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.05 1 – 1.11 0.0499 1843 18412 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.988 0.938 – 1.04 0.66 1677 15527 all phecode
214 Lipoma Neoplasms 0.974 0.92 – 1.03 0.368 1437 14132 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.964 0.895 – 1.04 0.329 883 8710 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.02 0.986 – 1.05 0.272 4528 39509 all phecode
216 Benign neoplasm of skin Neoplasms 0.93 0.909 – 0.951 1.67e-10 11528 34919 all phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 0.874 0.74 – 1.03 0.115 174 1701 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.834 0.792 – 0.878 5.7e-12 1786 17184 all phecode
217.1 Nevus, non-neoplastic Neoplasms 0.834 0.791 – 0.88 2.37e-11 1679 16116 all phecode
218 Benign neoplasm of uterus Neoplasms 0.989 0.955 – 1.02 0.541 4301 16661 all phecode
218.1 Uterine leiomyoma Neoplasms 0.957 0.909 – 1.01 0.0936 1835 15733 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.998 0.96 – 1.04 0.905 3403 16447 all phecode
220 Benign neoplasm of ovary Neoplasms 1.03 0.957 – 1.11 0.441 893 8783 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.01 0.96 – 1.06 0.759 2042 14248 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.904 0.848 – 0.963 0.00179 1133 10663 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.05 0.995 – 1.1 0.0746 1801 12657 all phecode
224 Benign neoplasm of eye Neoplasms 0.97 0.893 – 1.05 0.469 691 6752 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.962 0.88 – 1.05 0.4 595 5773 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.03 0.967 – 1.09 0.374 1209 12074 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.02 0.949 – 1.09 0.619 947 9454 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.02 0.902 – 1.16 0.718 289 2890 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 1 0.944 – 1.06 0.965 1329 13264 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.994 0.943 – 1.05 0.815 1690 16896 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.09 0.984 – 1.2 0.0991 467 4644 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.904 0.837 – 0.976 0.00993 795 7941 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.05 0.943 – 1.16 0.397 435 4350 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.858 0.818 – 0.899 1.55e-10 2149 20946 all phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.822 0.775 – 0.873 1.12e-10 1356 13336 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.986 0.961 – 1.01 0.273 7767 36615 all phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.973 0.944 – 1 0.064 5743 34218 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.02 0.953 – 1.09 0.581 1031 9761 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.03 0.99 – 1.07 0.142 2910 22227 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.02 0.979 – 1.07 0.301 2265 19902 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.07 1.01 – 1.14 0.0265 1304 12479 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.06 0.999 – 1.12 0.0527 1400 13425 all phecode
242.1 Graves' disease Endocrine/metabolic 1.07 0.969 – 1.17 0.188 515 5068 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.1 0.905 – 1.33 0.339 124 1224 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.05 0.923 – 1.19 0.48 292 2898 all phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 1.13 0.941 – 1.35 0.194 144 1432 all phecode
244 Hypothyroidism Endocrine/metabolic 1.07 1.04 – 1.09 2.56e-06 8099 32717 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.01 0.963 – 1.07 0.604 1762 17230 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.05 0.986 – 1.11 0.133 1261 11982 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.07 1.04 – 1.1 5.06e-06 7542 32208 all phecode
245 Thyroiditis Endocrine/metabolic 1.11 1.03 – 1.2 0.00746 832 7882 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.12 1.03 – 1.21 0.00995 686 6517 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.11 1.02 – 1.21 0.0146 679 6449 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.04 1.01 – 1.07 0.00684 6129 30240 all phecode
246.2 Thyroid cyst Endocrine/metabolic 0.841 0.679 – 1.04 0.112 101 960 all phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1.04 0.97 – 1.12 0.254 886 8696 all phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.36 1.26 – 1.46 2.03e-16 1150 8340 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.25 1.22 – 1.28 1.36e-81 13947 31815 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.29 1.21 – 1.37 5.17e-16 2364 11758 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.09 0.912 – 1.3 0.344 262 960 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.2 1.07 – 1.35 0.00269 551 2686 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.29 1.15 – 1.44 9.18e-06 784 3018 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.28 1.14 – 1.44 4.18e-05 638 2675 all phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 1.15 0.938 – 1.41 0.178 155 850 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.35 1.31 – 1.38 7.79e-107 9843 29688 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.34 1.14 – 1.58 0.000372 282 1327 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.48 1.4 – 1.57 6.99e-40 1941 13510 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.39 1.3 – 1.49 5.03e-21 1643 9668 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.49 1.41 – 1.57 2.15e-50 2557 16502 all phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.52 1.4 – 1.66 2.4e-21 860 6143 all phecode
250.3 Insulin pump user Endocrine/metabolic 1.41 1.35 – 1.48 1.27e-49 3496 20809 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.15 1.12 – 1.18 2.61e-22 8385 30645 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.09 1.03 – 1.15 0.00139 1870 15861 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.16 1.13 – 1.19 8.97e-23 7553 30071 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.15 0.953 – 1.4 0.143 136 1067 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.52 1.43 – 1.61 2.48e-44 2132 13390 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.19 1.12 – 1.26 6.95e-09 1691 10517 all phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.07 0.997 – 1.15 0.0621 991 8469 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.18 1.1 – 1.27 4.86e-06 1207 8570 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.05 1.01 – 1.1 0.0263 2282 22119 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.04 0.995 – 1.09 0.0762 2088 20335 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.01 0.918 – 1.11 0.84 508 5073 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.01 0.939 – 1.09 0.783 859 8544 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.03 0.907 – 1.18 0.62 263 2621 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.09 0.864 – 1.38 0.457 83 826 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.994 0.863 – 1.15 0.939 226 2250 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.14 0.91 – 1.43 0.253 86 860 all phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 1.07 0.882 – 1.29 0.511 121 1209 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.956 0.779 – 1.17 0.663 108 1080 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.11 1.05 – 1.18 0.000154 1506 14869 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.99 0.886 – 1.11 0.853 373 3730 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.08 0.921 – 1.26 0.35 183 1830 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.908 0.755 – 1.09 0.304 135 1350 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.07 0.983 – 1.17 0.114 626 6239 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.09 0.996 – 1.19 0.0614 596 5941 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.17 1.1 – 1.24 1.74e-06 1146 10513 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.27 1.17 – 1.37 3.7e-09 742 7128 all phecode
257 Testicular dysfunction Endocrine/metabolic 0.993 0.928 – 1.06 0.827 1015 9238 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.988 0.923 – 1.06 0.734 983 8933 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.15 0.926 – 1.44 0.202 91 910 all phecode
258.1 Postablative ovarian failure Endocrine/metabolic 1.04 0.844 – 1.27 0.733 109 1090 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.06 0.995 – 1.14 0.0686 1038 10259 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.06 1.02 – 1.1 0.00652 2880 26812 all phecode
260.1 Cachexia Endocrine/metabolic 1.01 0.888 – 1.14 0.901 292 2911 all phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.07 1.02 – 1.13 0.00755 1691 16847 all phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.08 0.986 – 1.17 0.101 614 6140 all phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.05 0.96 – 1.14 0.307 629 6236 all phecode
260.6 Anorexia Endocrine/metabolic 1.01 0.934 – 1.08 0.891 868 8591 all phecode
260.7 Polyphagia Endocrine/metabolic 1.15 0.886 – 1.49 0.296 65 643 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.11 1.08 – 1.14 2.7e-15 7718 35203 all phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1.15 0.884 – 1.5 0.296 69 690 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.23 1.14 – 1.33 4.48e-08 857 8405 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.11 1.08 – 1.14 2.4e-14 7255 35225 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.963 0.726 – 1.28 0.797 52 511 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.14 1.07 – 1.22 2.73e-05 1182 11676 all phecode
263 Other nutritional deficiency Endocrine/metabolic 1.07 1.02 – 1.13 0.00923 1651 15788 all phecode
264 Lack of normal physiological development Endocrine/metabolic 0.971 0.845 – 1.12 0.68 239 2301 all phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 0.912 0.752 – 1.11 0.349 122 1220 all phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 1.05 0.832 – 1.32 0.684 81 772 all phecode
269 Proteinuria Endocrine/metabolic 1.18 1.12 – 1.24 2.27e-09 1694 13981 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.04 0.971 – 1.12 0.257 967 9575 all phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 1.01 0.855 – 1.19 0.91 170 1697 all phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 1.02 0.849 – 1.22 0.845 134 1334 all phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 1.17 0.942 – 1.47 0.154 96 954 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.03 0.948 – 1.11 0.517 737 7303 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.09 0.978 – 1.22 0.116 384 3781 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.01 0.786 – 1.3 0.935 71 695 all phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 0.813 0.626 – 1.06 0.121 69 690 all phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1 0.884 – 1.13 0.986 299 2984 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1 0.961 – 1.04 0.984 2907 28132 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.995 0.955 – 1.04 0.828 2827 27425 all phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.11 0.902 – 1.37 0.323 102 1007 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.09 1.07 – 1.11 3.24e-15 18881 26670 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.09 1.07 – 1.11 3.35e-15 18843 26654 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.05 1.02 – 1.09 0.00116 5928 21600 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.12 1.06 – 1.19 0.000172 1360 11837 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.11 1.07 – 1.16 3.48e-07 3538 18449 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.04 0.918 – 1.17 0.558 313 3011 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.19 1.14 – 1.24 1.11e-14 2524 22729 all phecode
274.1 Gout Endocrine/metabolic 1.2 1.15 – 1.25 1.19e-15 2409 21991 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.19 1.11 – 1.27 2.81e-07 1082 10576 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.998 0.853 – 1.17 0.982 195 1890 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.982 0.836 – 1.15 0.819 183 1772 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.08 1.04 – 1.12 6.15e-06 4357 37091 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.946 0.815 – 1.1 0.462 218 2180 all phecode
275.11 Hereditary hemochromatosis Hematopoietic 1.04 0.831 – 1.29 0.757 99 990 all phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 1.08 0.822 – 1.42 0.581 62 614 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.2 1.12 – 1.28 2.83e-08 1154 11504 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.07 1.03 – 1.11 0.000814 3369 31544 all phecode
275.51 Hypocalcemia Endocrine/metabolic 1.03 0.962 – 1.11 0.358 898 8969 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.11 1.05 – 1.18 0.000381 1366 13634 all phecode
275.6 Hypercalcemia Endocrine/metabolic 1.04 0.98 – 1.1 0.201 1468 14183 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.12 1.09 – 1.14 1.65e-18 9238 37046 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.13 1.1 – 1.16 6.12e-17 6352 34366 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.16 1.05 – 1.27 0.002 550 5434 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.12 1.07 – 1.17 1.94e-07 2514 23219 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.16 1.11 – 1.21 7.4e-13 2992 25216 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.12 1.07 – 1.17 3.88e-06 2148 20909 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.15 1.09 – 1.2 1.49e-08 2086 20332 all phecode
276.41 Acidosis Endocrine/metabolic 1.14 1.08 – 1.2 3.53e-07 1788 17572 all phecode
276.42 Alkalosis Endocrine/metabolic 1.2 1.09 – 1.32 0.000279 476 4741 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.11 1.08 – 1.15 8.14e-11 4574 34527 all phecode
276.6 Fluid overload Endocrine/metabolic 1.28 1.21 – 1.36 2.52e-16 1384 13211 all phecode
276.8 Polydipsia Endocrine/metabolic 0.919 0.761 – 1.11 0.38 124 1240 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.11 1.07 – 1.15 2.54e-09 4112 35070 all phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.35 1.22 – 1.51 3.13e-08 403 3991 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.975 0.9 – 1.06 0.535 720 7161 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.03 0.963 – 1.11 0.365 936 9270 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.08 1 – 1.17 0.0491 773 7668 all phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.3 1.2 – 1.39 4.8e-12 916 8359 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.52 1.49 – 1.55 6.69e-350 19419 27331 all phecode
278.1 Obesity Endocrine/metabolic 1.6 1.57 – 1.64 5.98e-404 17129 27321 all phecode
278.11 Morbid obesity Endocrine/metabolic 1.85 1.8 – 1.9 3.58e-400 8280 27172 all phecode
278.3 Localized adiposity Endocrine/metabolic 1.65 1.46 – 1.86 3.98e-16 324 3228 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.35 1.29 – 1.42 9.53e-34 2104 17411 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.04 0.999 – 1.08 0.0574 2934 28612 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1.02 0.958 – 1.09 0.529 1161 11571 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.936 0.831 – 1.05 0.273 330 3278 all phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 1.01 0.931 – 1.09 0.87 754 7516 all phecode
279.7 Other immunological findings Endocrine/metabolic 1 0.973 – 1.04 0.802 4885 36552 all phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 0.984 0.901 – 1.07 0.716 601 5988 all phecode
280 Iron deficiency anemias Hematopoietic 1.12 1.08 – 1.15 5.85e-11 4626 30873 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.12 1.08 – 1.15 1.07e-10 4484 30649 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.1 1.05 – 1.16 0.000177 1771 17196 all phecode
281 Other deficiency anemia Hematopoietic 1.07 0.974 – 1.18 0.154 519 5120 all phecode
281.1 Megaloblastic anemia Hematopoietic 1.04 0.905 – 1.19 0.597 253 2497 all phecode
281.11 Pernicious anemia Hematopoietic 1.09 0.892 – 1.33 0.403 114 1108 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.05 0.896 – 1.23 0.55 187 1817 all phecode
281.9 Deficiency anemias Hematopoietic 1.05 0.919 – 1.19 0.493 285 2830 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.17 1.03 – 1.32 0.0134 323 3188 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.12 0.963 – 1.3 0.142 216 2113 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.24 1.06 – 1.46 0.00638 192 1920 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.19 1 – 1.41 0.0486 155 1550 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.27 0.972 – 1.67 0.0794 64 633 all phecode
284 Aplastic anemia Hematopoietic 1.04 0.958 – 1.13 0.354 697 6943 all phecode
284.1 Pancytopenia Hematopoietic 1.04 0.955 – 1.14 0.359 612 6100 all phecode
285 Other anemias Hematopoietic 1.08 1.06 – 1.11 8.18e-12 11794 33591 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.09 1.05 – 1.13 6.82e-06 3325 27709 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.14 1.09 – 1.19 9.46e-08 2055 19939 all phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.22 1.13 – 1.31 6.36e-08 932 9106 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.03 0.948 – 1.12 0.485 690 6892 all phecode
286 Coagulation defects Hematopoietic 1.08 1.05 – 1.12 8.31e-06 3844 33384 all phecode
286.1 Congenital coagulation defects Hematopoietic 1.07 0.937 – 1.23 0.309 250 2466 all phecode
286.11 Von willebrand's disease Hematopoietic 1.16 0.926 – 1.45 0.197 83 822 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.03 0.849 – 1.24 0.787 126 1260 all phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.11 1.06 – 1.15 2.36e-07 3354 25918 all phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 0.775 0.615 – 0.977 0.0309 97 962 all phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 1.13 0.991 – 1.3 0.0666 254 2529 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.04 0.875 – 1.24 0.64 132 1294 all phecode
286.6 Defibrination syndrome Hematopoietic 1.09 1.05 – 1.14 4.61e-05 2579 25377 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.09 1.04 – 1.13 3.49e-05 3014 29294 all phecode
286.8 Hypercoagulable state Hematopoietic 1.06 0.982 – 1.14 0.135 846 8437 all phecode
286.81 Primary hypercoagulable state Hematopoietic 1.05 0.971 – 1.13 0.232 813 8111 all phecode
286.9 Abnormal coagulation profile Hematopoietic 1.12 1.05 – 1.19 0.000676 1182 11487 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.05 1.01 – 1.09 0.00734 3288 28474 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.987 0.853 – 1.14 0.863 211 2094 all phecode
287.3 Thrombocytopenia Hematopoietic 1.04 1 – 1.09 0.0309 2938 26323 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.06 0.974 – 1.16 0.172 601 5994 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.99 0.904 – 1.08 0.83 569 5686 all phecode
287.4 Qualitative platelet defects Hematopoietic 1.19 0.971 – 1.45 0.0941 112 1120 all phecode
288 Diseases of white blood cells Hematopoietic 1.07 1.03 – 1.1 6.57e-05 4886 36527 all phecode
288.1 Decreased white blood cell count Hematopoietic 1.01 0.954 – 1.06 0.808 1599 15951 all phecode
288.11 Neutropenia Hematopoietic 1 0.942 – 1.07 0.89 1106 11041 all phecode
288.2 Elevated white blood cell count Hematopoietic 1.08 1.05 – 1.12 3.51e-06 4082 35079 all phecode
288.3 Eosinophilia Hematopoietic 0.835 0.713 – 0.978 0.0249 187 1866 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.02 0.971 – 1.08 0.393 1757 17434 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.992 0.924 – 1.07 0.836 918 9087 all phecode
289.4 Lymphadenitis Hematopoietic 1.05 1.02 – 1.09 0.00399 3888 34715 all phecode
289.5 Diseases of spleen Hematopoietic 0.999 0.896 – 1.11 0.982 393 3913 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.13 0.99 – 1.29 0.0702 255 2550 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.13 1.01 – 1.26 0.0327 385 3813 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.03 0.974 – 1.1 0.264 1318 11547 all phecode
290.1 Dementias Mental Disorders 1 0.914 – 1.1 0.947 541 4910 all phecode
290.11 Alzheimer's disease Mental Disorders 1.05 0.879 – 1.27 0.569 151 1389 all phecode
290.12 Dementia with cerebral degenerations Mental Disorders 0.97 0.77 – 1.22 0.798 88 846 all phecode
290.13 Senile dementia Mental Disorders 0.98 0.871 – 1.1 0.738 340 3078 all phecode
290.16 Vascular dementia Mental Disorders 0.823 0.646 – 1.05 0.115 81 777 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.06 0.98 – 1.15 0.144 750 7358 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.958 0.892 – 1.03 0.246 886 8618 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.02 0.982 – 1.07 0.259 2550 24810 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.97 0.827 – 1.14 0.713 175 1750 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.976 0.886 – 1.08 0.631 484 4807 all phecode
291.8 Alteration of consciousness Mental Disorders 1.03 0.987 – 1.09 0.16 2036 19974 all phecode
292 Neurological disorders Mental Disorders 1.03 1 – 1.06 0.0501 5733 38553 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.01 0.962 – 1.06 0.723 2013 19867 all phecode
292.11 Aphasia Mental Disorders 1.01 0.929 – 1.1 0.829 664 6581 all phecode
292.12 Symbolic dysfunction Mental Disorders 1.05 0.908 – 1.22 0.489 200 1988 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.98 0.878 – 1.09 0.72 389 3731 all phecode
292.3 Memory loss Mental Disorders 0.97 0.924 – 1.02 0.224 1922 18158 all phecode
292.4 Altered mental status Mental Disorders 1.08 1.03 – 1.13 0.000709 2454 22725 all phecode
292.5 Transient alteration of awareness Mental Disorders 0.999 0.903 – 1.11 0.99 430 4285 all phecode
292.6 Hallucinations Mental Disorders 1.09 0.941 – 1.26 0.253 217 2147 all phecode
293 Symptoms involving head and neck Mental Disorders 0.864 0.777 – 0.96 0.0065 414 4127 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.02 0.989 – 1.06 0.196 4417 38609 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.07 0.997 – 1.15 0.0613 885 8229 all phecode
295.1 Schizophrenia Mental Disorders 1.04 0.868 – 1.25 0.653 138 1339 all phecode
295.2 Paranoid disorders Mental Disorders 1.11 0.911 – 1.36 0.295 118 1079 all phecode
295.3 Psychosis Mental Disorders 1.08 0.999 – 1.18 0.0523 716 6694 all phecode
296 Mood disorders Mental Disorders 1.08 1.05 – 1.1 3.04e-11 15356 20858 all phecode
296.1 Bipolar Mental Disorders 1.14 1.07 – 1.21 4.34e-05 1301 11264 all phecode
296.2 Depression Mental Disorders 1.08 1.06 – 1.1 4.15e-11 14833 20856 all phecode
296.22 Major depressive disorder Mental Disorders 1.08 1.05 – 1.1 1.67e-10 13850 20853 all phecode
297 Suicidal ideation or attempt Mental Disorders 1.11 1.04 – 1.19 0.00276 985 9050 all phecode
297.1 Suicidal ideation Mental Disorders 1.1 1.02 – 1.19 0.0124 788 7310 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.05 0.927 – 1.2 0.424 285 2654 all phecode
300 Anxiety disorders Mental Disorders 1.05 1.03 – 1.08 4.78e-06 15419 20850 all phecode
300.1 Anxiety disorder Mental Disorders 1.06 1.04 – 1.08 6.85e-07 14517 20855 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1.05 1.01 – 1.08 0.00712 5546 20512 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.02 0.963 – 1.09 0.446 1360 11377 all phecode
300.13 Phobia Mental Disorders 1.08 1 – 1.15 0.0376 1051 9542 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.928 0.823 – 1.04 0.216 328 3018 all phecode
300.4 Dysthymic disorder Mental Disorders 1.06 1.01 – 1.11 0.019 2420 16552 all phecode
300.8 Acute reaction to stress Mental Disorders 1 0.907 – 1.11 0.979 504 4825 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.1 1.02 – 1.18 0.0151 843 7909 all phecode
301 Personality disorders Mental Disorders 1.1 0.998 – 1.22 0.0552 477 4539 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.08 0.947 – 1.24 0.24 254 2393 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.97 0.933 – 1.01 0.124 3700 13808 all phecode
302.1 Decreased libido Mental Disorders 0.925 0.836 – 1.02 0.135 447 4331 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.934 0.906 – 0.962 5.11e-06 6808 20043 all phecode
303.1 Dissociative disorder Mental Disorders 1.13 0.956 – 1.34 0.15 161 1573 all phecode
303.3 Psychogenic disorder Mental Disorders 0.923 0.895 – 0.951 1.77e-07 6487 19888 all phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.936 0.848 – 1.03 0.194 471 4623 all phecode
303.4 Somatoform disorder Mental Disorders 1 0.94 – 1.07 0.962 1177 11180 all phecode
304 Adjustment reaction Mental Disorders 1.03 0.989 – 1.06 0.174 3888 20475 all phecode
305.2 Eating disorder Mental Disorders 1.28 1.19 – 1.38 2.54e-11 901 8329 all phecode
306 Other mental disorder Mental Disorders 1.05 0.996 – 1.11 0.0692 1815 14133 all phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.09 0.996 – 1.2 0.0599 587 3527 all phecode
306.9 Tension headache Mental Disorders 1.06 0.976 – 1.14 0.174 753 7277 all phecode
312 Conduct disorders Mental Disorders 1.12 0.98 – 1.28 0.0976 254 2501 all phecode
312.3 Impulse control disorder Mental Disorders 1.11 0.871 – 1.41 0.404 74 736 all phecode
313 Pervasive developmental disorders Mental Disorders 1.02 0.971 – 1.08 0.373 1571 14633 all phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1.03 0.971 – 1.09 0.34 1392 13190 all phecode
313.2 Tics and stuttering Mental Disorders 1.06 0.837 – 1.34 0.627 77 770 all phecode
313.3 Autism Mental Disorders 0.907 0.693 – 1.19 0.473 64 621 all phecode
315 Develomental delays and disorders Mental Disorders 1.05 0.968 – 1.14 0.231 684 6788 all phecode
315.1 Learning disorder Mental Disorders 1.17 0.944 – 1.45 0.152 87 860 all phecode
315.2 Speech and language disorder Mental Disorders 0.938 0.82 – 1.07 0.351 254 2539 all phecode
316 Substance addiction and disorders Mental Disorders 1.14 1.1 – 1.18 6.36e-13 3682 32680 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.01 0.931 – 1.11 0.737 634 6331 all phecode
317 Alcohol-related disorders Mental Disorders 1.05 1.01 – 1.1 0.0159 2525 22920 all phecode
317.1 Alcoholism Mental Disorders 1.04 0.992 – 1.09 0.101 1986 19339 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.02 0.918 – 1.13 0.725 408 4080 all phecode
318 Tobacco use disorder Mental Disorders 1.17 1.14 – 1.2 3.88e-36 8622 34842 all phecode
320 Meningitis Neurological 0.989 0.886 – 1.1 0.846 382 3820 all phecode
323 Encephalitis Neurological 1.05 0.901 – 1.23 0.515 181 1809 all phecode
323.8 Encephalitis, non-infectious Neurological 1.09 0.918 – 1.29 0.334 153 1527 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.05 0.929 – 1.19 0.421 288 2880 all phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 1.04 0.785 – 1.39 0.765 53 530 all phecode
327 Sleep disorders Neurological 1.16 1.14 – 1.19 7.33e-46 14941 31602 all phecode
327.1 Hypersomnia Neurological 1.09 1.03 – 1.14 0.000785 2061 19110 all phecode
327.3 Sleep apnea Neurological 1.23 1.21 – 1.26 1.59e-69 10909 31304 all phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1.07 0.972 – 1.18 0.168 492 4784 all phecode
327.32 Obstructive sleep apnea Neurological 1.25 1.21 – 1.28 1.35e-63 8744 30530 all phecode
327.4 Insomnia Neurological 1.06 1.03 – 1.1 5.02e-05 5524 30960 all phecode
327.41 Organic or persistent insomnia Neurological 1.02 0.962 – 1.09 0.483 1265 12120 all phecode
327.5 Parasomnia Neurological 1.15 1.05 – 1.25 0.00155 604 5913 all phecode
327.6 Circadian rhythm sleep disorder Neurological 1.06 0.93 – 1.21 0.376 274 2666 all phecode
327.7 Sleep related movement disorders Neurological 1.15 1.09 – 1.21 2.32e-07 1786 17323 all phecode
327.71 Restless legs syndrome Neurological 1.17 1.1 – 1.23 5.82e-08 1570 15360 all phecode
327.72 Sleep related leg cramps Neurological 0.963 0.765 – 1.21 0.746 83 822 all phecode
331 Other cerebral degenerations Neurological 0.954 0.88 – 1.03 0.245 717 7024 all phecode
331.1 Hydrocephalus Neurological 0.976 0.861 – 1.11 0.704 284 2836 all phecode
331.9 Cerebral degeneration, unspecified Neurological 0.955 0.86 – 1.06 0.386 419 4026 all phecode
332 Parkinson's disease Neurological 0.965 0.868 – 1.07 0.517 415 4128 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.05 1 – 1.09 0.0283 2868 26583 all phecode
333.1 Essential tremor Neurological 0.952 0.879 – 1.03 0.228 725 7163 all phecode
333.2 Myoclonus Neurological 1.15 0.978 – 1.36 0.0898 159 1590 all phecode
333.4 Torsion dystonia Neurological 0.827 0.738 – 0.927 0.0011 352 3504 all phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 0.903 0.721 – 1.13 0.373 89 890 all phecode
334 Degenerative disease of the spinal cord Neurological 1.1 1.03 – 1.18 0.00425 1058 10562 all phecode
334.1 Spinocerebellar disease Neurological 1.04 0.82 – 1.31 0.756 79 790 all phecode
334.2 Anterior horn cell disease Neurological 1.07 0.871 – 1.31 0.518 110 1080 all phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 0.97 0.755 – 1.25 0.81 71 693 all phecode
335 Multiple sclerosis Neurological 1.06 0.951 – 1.18 0.304 396 3951 all phecode
337 Disorders of the autonomic nervous system Neurological 1.04 0.96 – 1.12 0.355 808 7413 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.1 0.982 – 1.23 0.0995 370 3164 all phecode
338 Pain Neurological 1.08 1.05 – 1.1 1.41e-13 20346 26417 all phecode
338.1 Acute pain Neurological 1.06 1.04 – 1.08 1.46e-08 15582 26313 all phecode
338.2 Chronic pain Neurological 1.11 1.09 – 1.14 2.91e-19 10994 26368 all phecode
339 Other headache syndromes Neurological 1.04 1.02 – 1.07 0.000498 9242 34658 all phecode
340 Migraine Neurological 1.04 1.01 – 1.07 0.00622 6708 30587 all phecode
340.1 Migrain with aura Neurological 1.03 0.991 – 1.07 0.142 3624 23684 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.1 0.919 – 1.33 0.289 133 1330 all phecode
342 Hemiplegia Neurological 1.02 0.923 – 1.13 0.695 464 4607 all phecode
343 Infantile cerebral palsy Neurological 0.953 0.759 – 1.2 0.679 85 847 all phecode
344 Other paralytic syndromes Neurological 1.03 0.951 – 1.12 0.452 682 6808 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.02 0.974 – 1.06 0.471 2553 25307 all phecode
345.1 Epilepsy Neurological 0.985 0.91 – 1.07 0.699 747 7465 all phecode
345.11 Generalized convulsive epilepsy Neurological 0.96 0.836 – 1.1 0.566 233 2330 all phecode
345.12 Partial epilepsy Neurological 0.997 0.909 – 1.09 0.942 534 5335 all phecode
345.3 Convulsions Neurological 1.02 0.974 – 1.06 0.429 2396 23796 all phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.95 0.812 – 1.11 0.524 183 1824 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.99 0.936 – 1.05 0.715 1472 14587 all phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.907 0.745 – 1.1 0.332 120 1181 all phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 1.04 0.845 – 1.27 0.723 110 1100 all phecode
347 Cataplexy and narcolepsy Neurological 1.09 0.877 – 1.36 0.428 101 1010 all phecode
348 Other conditions of brain Neurological 1.06 1.01 – 1.12 0.0242 1793 17894 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.05 0.976 – 1.12 0.202 905 9034 all phecode
348.4 Cerebral cysts Neurological 1.02 0.888 – 1.18 0.737 229 2290 all phecode
348.7 Coma Neurological 0.977 0.848 – 1.13 0.753 229 2275 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.09 1.02 – 1.18 0.0183 853 8479 all phecode
348.9 Other conditions of brain, NOS Neurological 0.981 0.939 – 1.03 0.409 2341 23287 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.06 0.984 – 1.13 0.13 941 9385 all phecode
350 Abnormal movement Neurological 1.03 1.01 – 1.06 0.0152 6706 38762 all phecode
350.1 Abnormal involuntary movements Neurological 1.04 1 – 1.08 0.0388 3273 30524 all phecode
350.2 Abnormality of gait Neurological 1.04 1 – 1.07 0.0415 3920 30520 all phecode
350.3 Lack of coordination Neurological 0.975 0.914 – 1.04 0.444 1062 10554 all phecode
350.5 Abnormal reflex Neurological 1.02 0.88 – 1.19 0.752 200 1988 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.02 0.932 – 1.12 0.652 558 5576 all phecode
351 Other peripheral nerve disorders Neurological 1.09 1.06 – 1.12 1.99e-10 7401 34460 all phecode
352 Disorders of other cranial nerves Neurological 1 0.949 – 1.05 0.997 1714 17106 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.944 0.859 – 1.04 0.233 535 5344 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.02 0.946 – 1.1 0.591 783 7826 all phecode
353 Nerve root and plexus disorders Neurological 1.06 1.03 – 1.1 0.000372 4256 33369 all phecode
353.1 Nerve plexus lesions Neurological 1.08 0.967 – 1.2 0.174 390 3900 all phecode
353.2 Nerve root lesions Neurological 0.959 0.793 – 1.16 0.665 130 1287 all phecode
355 Complex regional/central pain syndrome Neurological 1.05 0.952 – 1.15 0.351 531 5295 all phecode
355.1 Chronic pain syndrome Neurological 1.1 1.03 – 1.19 0.008 843 8386 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.06 1.01 – 1.11 0.0117 2335 20731 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.09 1.05 – 1.13 1.71e-05 3472 29956 all phecode
358 Myoneural disorders Neurological 1.09 1.02 – 1.16 0.00759 1147 11391 all phecode
358.1 Myasthenia gravis Neurological 0.871 0.714 – 1.06 0.175 109 1082 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.942 0.883 – 1 0.0678 1134 11274 all phecode
359.1 Muscular dystrophies Neurological 0.806 0.607 – 1.07 0.135 64 632 all phecode
359.2 Myopathy Neurological 0.953 0.893 – 1.02 0.154 1092 10843 all phecode
360 Disorders of the globe Sense Organs 0.885 0.732 – 1.07 0.203 131 1276 all phecode
360.2 Progressive myopia Sense Organs 0.82 0.628 – 1.07 0.146 65 640 all phecode
361 Retinal detachments and defects Sense Organs 0.951 0.878 – 1.03 0.22 733 7131 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.869 0.767 – 0.984 0.0271 302 2962 all phecode
362 Other retinal disorders Sense Organs 0.978 0.942 – 1.02 0.259 3569 22997 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.972 0.926 – 1.02 0.254 2172 15483 all phecode
362.21 Macular degeneration, dry Sense Organs 0.903 0.811 – 1.01 0.0665 419 3438 all phecode
362.22 Macular degeneration, wet Sense Organs 1.09 0.904 – 1.31 0.366 148 1184 all phecode
362.23 Cystoid macular degeneration of retina Sense Organs 0.91 0.817 – 1.01 0.0837 408 3839 all phecode
362.26 Macular puckering of retina Sense Organs 0.966 0.9 – 1.04 0.327 976 8610 all phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.868 0.785 – 0.96 0.00598 488 4558 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.983 0.933 – 1.03 0.51 1883 13955 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.04 0.968 – 1.11 0.29 976 8527 all phecode
362.31 Separation of retinal layers Sense Organs 0.988 0.889 – 1.1 0.817 413 4056 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.983 0.903 – 1.07 0.698 662 5933 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.903 0.81 – 1.01 0.068 392 3787 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.889 0.768 – 1.03 0.116 215 2103 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.13 0.984 – 1.3 0.0842 241 2368 all phecode
362.9 Retinal edema Sense Organs 1.1 0.975 – 1.24 0.121 324 2936 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.897 0.814 – 0.989 0.0292 492 4746 all phecode
363.3 Chorioretinal scars Sense Organs 0.845 0.751 – 0.95 0.00476 332 3184 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.942 0.882 – 1.01 0.0718 1132 10772 all phecode
364.1 Corneal opacity Sense Organs 0.934 0.839 – 1.04 0.216 394 3846 all phecode
364.2 Corneal edema Sense Organs 1.06 0.877 – 1.28 0.543 123 1208 all phecode
364.4 Corneal degenerations Sense Organs 0.963 0.864 – 1.07 0.49 402 3962 all phecode
364.41 Keratoconus Sense Organs 0.735 0.575 – 0.939 0.0139 75 739 all phecode
364.5 Corneal dystrophy Sense Organs 0.932 0.844 – 1.03 0.166 502 4682 all phecode
364.51 Fuchs' dystrophy Sense Organs 0.876 0.764 – 1 0.0587 266 2521 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.877 0.7 – 1.1 0.256 91 885 all phecode
365 Glaucoma Sense Organs 0.969 0.928 – 1.01 0.148 2672 21326 all phecode
365.1 Open-angle glaucoma Sense Organs 0.929 0.856 – 1.01 0.0778 705 6491 all phecode
365.11 Primary open angle glaucoma Sense Organs 0.906 0.812 – 1.01 0.0735 403 3681 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.985 0.856 – 1.13 0.835 251 2370 all phecode
366 Cataract Sense Organs 0.987 0.961 – 1.01 0.358 8611 28043 all phecode
366.1 Nonsenile Cataract Sense Organs 0.892 0.766 – 1.04 0.14 207 1979 all phecode
366.2 Senile cataract Sense Organs 0.975 0.944 – 1.01 0.129 5480 24980 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.962 0.938 – 0.986 0.00195 8967 37779 all phecode
367.1 Myopia Sense Organs 0.936 0.907 – 0.966 4.38e-05 5014 34677 all phecode
367.2 Astigmatism Sense Organs 0.934 0.902 – 0.966 8.74e-05 4161 32463 all phecode
367.8 Hypermetropia Sense Organs 0.941 0.896 – 0.987 0.013 2039 18599 all phecode
367.9 Blindness and low vision Sense Organs 1.03 0.97 – 1.09 0.338 1277 12356 all phecode
368 Visual disturbances Sense Organs 1.02 0.989 – 1.05 0.216 5715 39599 all phecode
368.1 Amblyopia Sense Organs 1.05 0.961 – 1.14 0.302 651 6479 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.04 0.972 – 1.11 0.272 1087 10786 all phecode
368.3 Anisometropia Sense Organs 0.846 0.731 – 0.981 0.0263 219 2168 all phecode
368.4 Visual field defects Sense Organs 0.983 0.923 – 1.05 0.607 1132 11173 all phecode
368.9 Subjective visual disturbances Sense Organs 1.03 0.963 – 1.1 0.392 1070 10620 all phecode
368.91 Psychophysical visual disturbances Sense Organs 1.28 1.05 – 1.55 0.0157 120 1171 all phecode
369 Infection of the eye Sense Organs 0.948 0.912 – 0.985 0.00628 3185 28240 all phecode
369.2 Eye infection, viral Sense Organs 0.948 0.86 – 1.04 0.28 502 4954 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.947 0.909 – 0.988 0.0109 2716 24970 all phecode
370 Keratitis Sense Organs 0.937 0.884 – 0.994 0.0301 1365 13169 all phecode
370.1 Corneal ulcer Sense Organs 0.871 0.755 – 1 0.0574 223 2194 all phecode
370.2 Superficial keratitis Sense Organs 0.941 0.858 – 1.03 0.195 546 5393 all phecode
370.3 Keratoconjunctivitis Sense Organs 1.01 0.925 – 1.1 0.875 649 6263 all phecode
370.31 Keratoconjunctivitis sicca Sense Organs 1.01 0.856 – 1.19 0.932 179 1677 all phecode
371 Inflammation of the eye Sense Organs 0.946 0.915 – 0.979 0.00127 4414 32310 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1 0.913 – 1.1 0.955 541 5278 all phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.941 0.876 – 1.01 0.0981 906 8939 all phecode
371.21 Allergic conjunctivitis Sense Organs 0.932 0.861 – 1.01 0.0788 756 7515 all phecode
371.3 Inflammation of eyelids Sense Organs 0.94 0.905 – 0.976 0.0013 3398 26983 all phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 0.785 0.65 – 0.949 0.0125 133 1291 all phecode
372 Disorders of conjunctiva Sense Organs 0.964 0.904 – 1.03 0.264 1118 10728 all phecode
374 Other disorders of eyelids Sense Organs 0.936 0.899 – 0.975 0.00147 2940 24188 all phecode
374.1 Ectropion or entropion Sense Organs 0.89 0.802 – 0.988 0.029 431 4084 all phecode
374.2 Lagophthalmos Sense Organs 0.96 0.836 – 1.1 0.56 235 2335 all phecode
374.3 Ptosis of eyelid Sense Organs 0.963 0.902 – 1.03 0.261 1102 10734 all phecode
374.6 Dermatochalasis Sense Organs 0.985 0.921 – 1.05 0.67 1040 9720 all phecode
375 Disorders of lacrimal system Sense Organs 0.972 0.937 – 1.01 0.138 3694 26045 all phecode
375.1 Dry eyes Sense Organs 0.968 0.934 – 1 0.0752 4040 26751 all phecode
375.2 Epiphora Sense Organs 0.955 0.859 – 1.06 0.386 442 4354 all phecode
376 Disorders of the orbit Sense Organs 0.984 0.877 – 1.1 0.786 352 3508 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.03 0.962 – 1.11 0.371 913 9021 all phecode
377.1 Optic atrophy Sense Organs 0.941 0.827 – 1.07 0.351 283 2793 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.06 0.965 – 1.15 0.236 585 5775 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.987 0.93 – 1.05 0.682 1275 12460 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.01 0.939 – 1.09 0.759 828 8130 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.921 0.781 – 1.09 0.327 170 1686 all phecode
378.5 Paralytic strabismus Sense Organs 0.958 0.855 – 1.07 0.462 349 3437 all phecode
379 Other disorders of eye Sense Organs 0.959 0.929 – 0.991 0.0112 5046 29999 all phecode
379.1 Scleritis and episcleritis Sense Organs 0.891 0.756 – 1.05 0.169 176 1743 all phecode
379.2 Disorders of vitreous body Sense Organs 0.948 0.912 – 0.984 0.00538 3634 23186 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.892 0.743 – 1.07 0.221 135 1258 all phecode
379.4 Anomalies of pupillary function Sense Organs 0.95 0.837 – 1.08 0.429 287 2833 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.09 0.965 – 1.23 0.163 304 2948 all phecode
379.51 Pigmentary iris degeneration Sense Organs 0.867 0.672 – 1.12 0.271 77 731 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.992 0.93 – 1.06 0.818 1129 11130 all phecode
380 Disorders of external ear Sense Organs 0.908 0.867 – 0.951 4.26e-05 2242 20393 all phecode
380.1 Otitis externa Sense Organs 0.956 0.904 – 1.01 0.114 1469 14580 all phecode
380.4 Impacted cerumen Sense Organs 0.901 0.863 – 0.94 1.4e-06 2648 23557 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.996 0.963 – 1.03 0.808 4255 36417 all phecode
381.1 Otitis media Sense Organs 1.03 0.987 – 1.07 0.202 3079 29813 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.03 0.985 – 1.07 0.212 2610 25602 all phecode
381.2 Eustachian tube disorders Sense Organs 0.929 0.883 – 0.977 0.00422 1816 17827 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.11 0.942 – 1.32 0.207 153 1530 all phecode
381.9 Otorrhea Sense Organs 1.12 1 – 1.25 0.0463 372 3713 all phecode
382 Otalgia Sense Organs 1.01 0.958 – 1.06 0.793 1884 18673 all phecode
383 Otosclerosis Sense Organs 0.984 0.814 – 1.19 0.868 124 1240 all phecode
384 Other disorders of tympanic membrane Sense Organs 0.999 0.909 – 1.1 0.986 516 5156 all phecode
384.1 Myringitis Sense Organs 0.713 0.525 – 0.969 0.0309 51 502 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.01 0.906 – 1.12 0.884 403 4029 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.997 0.901 – 1.1 0.95 432 4320 all phecode
385.3 Cholesteatoma Sense Organs 1.02 0.904 – 1.16 0.704 277 2770 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.96 0.792 – 1.16 0.679 118 1180 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.01 0.959 – 1.06 0.736 1882 18186 all phecode
386.1 Meniere's disease Sense Organs 1.07 0.943 – 1.2 0.31 319 3156 all phecode
386.2 Peripheral or central vertigo Sense Organs 1.02 0.962 – 1.07 0.56 1586 15423 all phecode
386.21 Central origin vertigo Sense Organs 1.04 0.975 – 1.11 0.237 1208 11844 all phecode
386.3 Labyrinthitis Sense Organs 1.02 0.963 – 1.08 0.525 1482 14530 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.02 0.994 – 1.05 0.123 6933 38286 all phecode
388 Other disorders of ear Sense Organs 0.967 0.903 – 1.04 0.337 960 9501 all phecode
389 Hearing loss Sense Organs 0.976 0.952 – 1 0.0681 8182 38069 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.94 0.908 – 0.973 0.00045 4107 29258 all phecode
389.2 Conductive hearing loss Sense Organs 0.971 0.905 – 1.04 0.421 905 9042 all phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.9 0.77 – 1.05 0.183 192 1808 all phecode
389.4 Tinnitus Sense Organs 0.916 0.876 – 0.958 0.000138 2291 22130 all phecode
389.5 Disorders of acoustic nerve Sense Organs 1.03 0.855 – 1.24 0.748 124 1229 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.07 1.01 – 1.13 0.0198 1458 13732 all phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 1.08 0.961 – 1.21 0.201 350 3415 all phecode
394.2 Mitral valve disease Circulatory System 0.965 0.874 – 1.07 0.485 462 4560 all phecode
394.3 Aortic valve disease Circulatory System 1.2 1.02 – 1.42 0.0311 176 1691 all phecode
394.4 Acute rheumatic heart disease Circulatory System 0.891 0.675 – 1.18 0.419 55 546 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.09 1 – 1.19 0.0474 587 5739 all phecode
395 Heart valve disorders Circulatory System 1.02 0.98 – 1.05 0.404 3976 28748 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.96 0.916 – 1.01 0.0832 2175 20441 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.07 1.02 – 1.12 0.00913 2060 17194 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.06 0.966 – 1.17 0.207 493 4864 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.03 0.838 – 1.27 0.77 108 1080 all phecode
395.6 Heart valve replaced Circulatory System 1.08 1.01 – 1.15 0.0179 1177 10833 all phecode
396 Abnormal heart sounds Circulatory System 1.02 0.986 – 1.05 0.264 4718 34395 all phecode
401 Hypertension Circulatory System 1.27 1.24 – 1.3 3.49e-102 23317 23367 all phecode
401.1 Essential hypertension Circulatory System 1.27 1.25 – 1.3 1.86e-103 23158 23364 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.39 1.33 – 1.45 2.81e-51 3503 14616 all phecode
401.21 Hypertensive heart disease Circulatory System 1.32 1.22 – 1.42 1.01e-12 893 6607 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.38 1.31 – 1.44 1.04e-39 2584 13072 all phecode
401.3 Other hypertensive complications Circulatory System 1.27 1.22 – 1.33 1.04e-25 2679 15833 all phecode
411 Ischemic Heart Disease Circulatory System 1.15 1.12 – 1.18 2.39e-24 8807 30299 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.17 1.09 – 1.26 9.43e-06 937 8574 all phecode
411.2 Myocardial infarction Circulatory System 1.19 1.15 – 1.24 1.28e-19 3594 21716 all phecode
411.3 Angina pectoris Circulatory System 1.17 1.12 – 1.22 3.14e-12 2485 18304 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.15 1.12 – 1.18 1.93e-21 7555 27492 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.16 0.974 – 1.38 0.0961 156 1529 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.15 1.12 – 1.19 7.61e-20 6331 25741 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.19 1.07 – 1.32 0.000864 442 4211 all phecode
414 Other forms of chronic heart disease Circulatory System 1.1 1.06 – 1.15 1.51e-06 3101 22616 all phecode
414.2 ASCVD Circulatory System 1.07 0.991 – 1.16 0.0831 718 6816 all phecode
415 Pulmonary heart disease Circulatory System 1.14 1.1 – 1.18 4.25e-12 3366 30208 all phecode
415.1 Acute pulmonary heart disease Circulatory System 1.13 1.07 – 1.18 2.22e-06 1912 19014 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.13 1.07 – 1.18 2.21e-06 1906 18953 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.17 1.11 – 1.23 1.32e-09 1808 17605 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.12 1.04 – 1.22 0.0044 706 7032 all phecode
416 Cardiomegaly Circulatory System 1.09 1.03 – 1.16 0.004 1254 12372 all phecode
418 Nonspecific chest pain Circulatory System 1.04 1.02 – 1.07 8.05e-05 12650 33952 all phecode
418.1 Precordial pain Circulatory System 1.03 0.971 – 1.09 0.343 1471 13782 all phecode
420 Carditis Circulatory System 1.05 0.994 – 1.11 0.084 1588 15680 all phecode
420.1 Myocarditis Circulatory System 1.06 0.852 – 1.32 0.606 97 958 all phecode
420.2 Pericarditis Circulatory System 1.04 0.964 – 1.12 0.316 842 8402 all phecode
420.21 Acute pericarditis Circulatory System 1.23 1.04 – 1.45 0.0135 177 1764 all phecode
420.22 Chronic pericarditis Circulatory System 1.18 0.967 – 1.44 0.103 117 1153 all phecode
420.3 Endocarditis Circulatory System 1.1 1.01 – 1.18 0.0221 764 7535 all phecode
425 Cardiomyopathy Circulatory System 1.12 1.06 – 1.17 5.34e-06 2078 19881 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.12 1.07 – 1.18 4.77e-06 1989 19025 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.08 0.935 – 1.25 0.286 208 2050 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.11 0.955 – 1.3 0.17 201 1992 all phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.07 0.946 – 1.21 0.288 317 3170 all phecode
425.8 Other cardiomyopathy Circulatory System 1.13 0.897 – 1.41 0.306 95 931 all phecode
426 Cardiac conduction disorders Circulatory System 1.08 1.05 – 1.1 1.24e-09 12327 25440 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.11 1.06 – 1.17 6.12e-05 1903 11501 all phecode
426.21 First degree AV block Circulatory System 1.1 1.04 – 1.17 0.00229 1313 8899 all phecode
426.22 Mobitz II AV block Circulatory System 1.05 0.781 – 1.4 0.766 64 553 all phecode
426.23 Second degree AV block Circulatory System 1 0.863 – 1.16 0.974 216 1925 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.07 0.964 – 1.19 0.204 461 3823 all phecode
426.25 Other heart block Circulatory System 1.03 0.887 – 1.2 0.7 203 1803 all phecode
426.3 Bundle branch block Circulatory System 1.08 1.03 – 1.13 0.00154 2306 13999 all phecode
426.31 Right bundle branch block Circulatory System 1.06 0.997 – 1.12 0.0619 1423 10758 all phecode
426.32 Left bundle branch block Circulatory System 1.13 1.05 – 1.21 0.000925 969 8110 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.02 0.804 – 1.28 0.895 82 820 all phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.08 1.05 – 1.11 4.68e-09 10577 25186 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.15 1.05 – 1.25 0.00176 679 6650 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.1 1.04 – 1.16 0.000535 1754 11536 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.11 1.04 – 1.19 0.00148 1171 8184 all phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.09 1.01 – 1.18 0.0207 846 7320 all phecode
427 Cardiac dysrhythmias Circulatory System 1.05 1.03 – 1.07 5.19e-06 17397 25735 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.05 1 – 1.1 0.0321 2474 18178 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.05 0.994 – 1.11 0.0817 1595 14293 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.07 1 – 1.14 0.037 1181 9915 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.09 1.05 – 1.13 5.94e-07 5313 18688 all phecode
427.21 Atrial fibrillation Circulatory System 1.09 1.05 – 1.13 2.5e-06 5188 18409 all phecode
427.22 Atrial flutter Circulatory System 1.07 1.01 – 1.13 0.0178 1693 11042 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.06 1.03 – 1.09 3.75e-05 8688 25552 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.07 0.978 – 1.18 0.132 536 5233 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.908 0.786 – 1.05 0.186 216 2118 all phecode
427.42 Cardiac arrest Circulatory System 1.13 1.01 – 1.26 0.0281 410 4034 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.04 1.01 – 1.07 0.0165 6905 25457 all phecode
427.6 Premature beats Circulatory System 1.02 0.976 – 1.07 0.358 2359 16248 all phecode
427.61 Supraventricular premature beats Circulatory System 1.06 0.97 – 1.15 0.209 670 6287 all phecode
427.7 Tachycardia NOS Circulatory System 1.09 1.06 – 1.12 1.18e-07 5124 25531 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.09 1.01 – 1.17 0.0231 912 7501 all phecode
427.9 Palpitations Circulatory System 0.989 0.956 – 1.02 0.514 4430 24505 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.2 1.16 – 1.24 1.54e-23 4300 23663 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.21 1.16 – 1.25 4.75e-23 3756 22446 all phecode
428.2 Heart failure NOS Circulatory System 1.22 1.18 – 1.27 2.37e-25 3701 21722 all phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.2 1.14 – 1.27 2.84e-12 1765 14476 all phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.26 1.19 – 1.33 2.82e-16 1648 13395 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.06 1.04 – 1.09 2.75e-08 12635 32504 all phecode
429.1 Heart transplant/surgery Circulatory System 1.07 1.01 – 1.14 0.0293 1219 11696 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.1 1.06 – 1.13 9.66e-10 6322 29232 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.05 1.03 – 1.08 2.9e-05 9650 32421 all phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.11 1.02 – 1.2 0.0134 723 7072 all phecode
430 Intracranial hemorrhage Circulatory System 0.932 0.863 – 1.01 0.0745 789 7842 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.967 0.845 – 1.11 0.621 261 2610 all phecode
430.2 Intracerebral hemorrhage Circulatory System 0.965 0.862 – 1.08 0.534 368 3671 all phecode
430.3 Subdural hemorrhage Circulatory System 0.867 0.761 – 0.987 0.0316 272 2680 all phecode
433 Cerebrovascular disease Circulatory System 1.08 1.04 – 1.11 2.3e-06 5463 32242 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.06 1.01 – 1.11 0.0218 1978 16212 all phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.15 1 – 1.32 0.0459 260 2517 all phecode
433.12 Cerebral atherosclerosis Circulatory System 0.934 0.733 – 1.19 0.585 80 789 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.1 1.06 – 1.15 1.07e-05 2437 21732 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.1 1.06 – 1.15 1.44e-05 2357 21103 all phecode
433.3 Cerebral ischemia Circulatory System 1.05 1.01 – 1.09 0.0239 2780 22868 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.07 1.02 – 1.12 0.00389 2409 20762 all phecode
433.5 Cerebral aneurysm Circulatory System 1.05 0.951 – 1.16 0.334 474 4724 all phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.1 0.998 – 1.22 0.0552 464 4518 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.12 1.03 – 1.21 0.00786 695 6822 all phecode
440 Atherosclerosis Circulatory System 1.14 1.09 – 1.19 1.11e-08 2477 19724 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.04 0.903 – 1.2 0.587 231 2291 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.14 1.08 – 1.21 5.31e-06 1516 13532 all phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.22 1.07 – 1.39 0.00309 274 2669 all phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.11 1.04 – 1.19 0.00211 1040 9647 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.14 1.06 – 1.23 0.00041 846 8124 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.07 0.972 – 1.18 0.171 515 5115 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.12 0.976 – 1.29 0.105 240 2387 all phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.04 0.87 – 1.24 0.689 154 1536 all phecode
442 Other aneurysm Circulatory System 1.11 1.06 – 1.15 2.01e-06 2779 21466 all phecode
442.1 Aortic aneurysm Circulatory System 1.11 1.06 – 1.16 2.55e-05 2054 16492 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.1 1.03 – 1.17 0.00341 1189 10558 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.07 0.918 – 1.24 0.388 202 2002 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.984 0.838 – 1.16 0.845 179 1765 all phecode
442.4 Arterial dissection Circulatory System 1.03 0.876 – 1.2 0.757 184 1840 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.12 1.01 – 1.25 0.0395 399 3978 all phecode
443 Peripheral vascular disease Circulatory System 1.07 1.03 – 1.11 0.00063 3086 24814 all phecode
443.1 Raynaud's syndrome Circulatory System 0.845 0.781 – 0.915 3.13e-05 742 7390 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.32 1.14 – 1.53 0.000236 220 2087 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.07 1.03 – 1.12 0.00153 2557 21985 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.15 1.1 – 1.2 3.28e-09 2341 18862 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.12 1.04 – 1.2 0.00365 848 8423 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.08 0.961 – 1.22 0.189 313 3099 all phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 1.08 0.907 – 1.28 0.396 155 1548 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.01 0.913 – 1.12 0.843 460 4559 all phecode
446.4 Wegener's granulomatosis Circulatory System 0.818 0.664 – 1.01 0.059 109 1075 all phecode
446.5 Giant cell arteritis Circulatory System 0.852 0.669 – 1.08 0.192 79 749 all phecode
446.9 Arteritis NOS Circulatory System 1.06 0.931 – 1.2 0.4 289 2876 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.07 1.02 – 1.11 0.00268 2647 22765 all phecode
447.1 Stricture of artery Circulatory System 1.11 1.01 – 1.22 0.0316 523 5163 all phecode
447.7 Aortic ectasia Circulatory System 1.02 0.949 – 1.1 0.54 804 7938 all phecode
448 Disease of capillaries Circulatory System 0.861 0.809 – 0.917 2.62e-06 1237 12127 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.08 1.03 – 1.13 0.00121 2104 20985 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.03 0.951 – 1.11 0.476 738 7355 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.07 0.933 – 1.23 0.325 244 2437 all phecode
452 Other venous embolism and thrombosis Circulatory System 1.12 1.09 – 1.16 1.96e-12 4957 29867 all phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1.01 0.893 – 1.15 0.832 276 2747 all phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1.12 1.08 – 1.16 8.21e-09 3260 26940 all phecode
452.8 Postphlebitic syndrome Circulatory System 1.07 0.902 – 1.26 0.453 154 1529 all phecode
453 Chronic venous hypertension Circulatory System 1.14 0.984 – 1.32 0.0809 220 2168 all phecode
454 Varicose veins Circulatory System 1.05 1.01 – 1.09 0.022 2827 24555 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1.06 1.02 – 1.11 0.0051 2469 21426 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.08 1.02 – 1.14 0.00542 1565 15056 all phecode
455 Hemorrhoids Circulatory System 0.955 0.927 – 0.984 0.00266 5799 29818 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.08 1.03 – 1.12 0.000298 3097 24898 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.09 1.04 – 1.15 0.000286 2095 15309 all phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.12 0.999 – 1.27 0.0529 324 3221 all phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.09 1.04 – 1.14 0.000884 1973 14689 all phecode
458 Hypotension Circulatory System 1.1 1.07 – 1.14 1.11e-09 5091 32185 all phecode
458.1 Orthostatic hypotension Circulatory System 1.06 0.998 – 1.12 0.0581 1344 12938 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.12 1.05 – 1.19 0.000669 1109 11012 all phecode
458.9 Hypotension NOS Circulatory System 1.1 1.07 – 1.14 3.03e-09 4618 31186 all phecode
459 Other disorders of circulatory system Circulatory System 1.09 1.06 – 1.12 5.77e-11 7825 34792 all phecode
459.1 Hemorrhage NOS Circulatory System 1.02 0.946 – 1.1 0.617 834 8215 all phecode
459.7 Blood vessel replaced Circulatory System 1.19 1.12 – 1.26 1.8e-08 1305 13023 all phecode
459.9 Circulatory disease NEC Circulatory System 1.09 1.06 – 1.12 1.48e-09 6706 33592 all phecode
464 Acute sinusitis Respiratory 0.971 0.94 – 1 0.0698 4792 32137 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.973 0.95 – 0.996 0.0232 9601 35915 all phecode
465.2 Acute pharyngitis Respiratory 0.959 0.93 – 0.989 0.008 5310 32365 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.02 0.92 – 1.13 0.712 443 4428 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.91 0.864 – 0.957 0.00026 1797 17640 all phecode
471 Nasal polyps Respiratory 0.916 0.839 – 1 0.0498 592 5881 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.943 0.896 – 0.993 0.0256 1797 16986 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1.02 0.977 – 1.06 0.4 2983 25244 all phecode
473.1 Chronic laryngitis Respiratory 1.11 0.863 – 1.44 0.408 68 674 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.986 0.905 – 1.07 0.756 628 6254 all phecode
473.4 Voice disturbance Respiratory 1.01 0.969 – 1.06 0.574 2336 21975 all phecode
474 Acute and chronic tonsillitis Respiratory 1 0.933 – 1.08 0.912 880 7892 all phecode
474.1 Acute tonsillitis Respiratory 0.869 0.772 – 0.978 0.02 335 3181 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.04 0.954 – 1.12 0.405 700 6445 all phecode
475 Chronic sinusitis Respiratory 0.965 0.933 – 0.998 0.0385 4378 27891 all phecode
475.9 Postnasal drip Respiratory 0.885 0.824 – 0.951 0.000861 922 9017 all phecode
476 Allergic rhinitis Respiratory 0.985 0.964 – 1.01 0.193 12687 28117 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.1 1.03 – 1.17 0.00283 1150 11318 all phecode
478 Throat pain Respiratory 0.995 0.898 – 1.1 0.928 426 4195 all phecode
479 Other upper respiratory disease Respiratory 0.994 0.965 – 1.02 0.717 5627 28048 all phecode
480 Pneumonia Respiratory 1.07 1.04 – 1.1 2e-06 5947 37034 all phecode
480.1 Bacterial pneumonia Respiratory 1.08 1.01 – 1.15 0.0234 1155 11495 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.12 1.02 – 1.23 0.0135 568 5644 all phecode
480.12 Pseudomonal pneumonia Respiratory 0.965 0.81 – 1.15 0.693 153 1523 all phecode
480.13 MRSA pneumonia Respiratory 1.1 0.907 – 1.34 0.324 117 1165 all phecode
480.2 Viral pneumonia Respiratory 1.15 0.986 – 1.33 0.0752 202 1992 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.08 0.909 – 1.28 0.386 159 1590 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.13 0.94 – 1.36 0.19 135 1312 all phecode
481 Influenza Respiratory 0.998 0.941 – 1.06 0.958 1355 13284 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.03 0.996 – 1.07 0.0781 3412 29871 all phecode
495 Asthma Respiratory 1.1 1.08 – 1.13 1.23e-14 8671 33569 all phecode
495.1 Chronic obstructive asthma Respiratory 1.23 1.1 – 1.37 0.000184 397 3925 all phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 1.14 0.891 – 1.45 0.301 81 802 all phecode
495.2 Asthma with exacerbation Respiratory 1.07 1.01 – 1.13 0.0131 1629 16033 all phecode
496 Chronic airway obstruction Respiratory 1.18 1.14 – 1.22 6.45e-25 5343 28343 all phecode
496.1 Emphysema Respiratory 1.16 1.1 – 1.21 1.88e-09 2134 19414 all phecode
496.2 Chronic bronchitis Respiratory 1.23 1.19 – 1.27 5.06e-31 4128 26624 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.24 1.2 – 1.29 3.22e-31 3747 25467 all phecode
496.3 Bronchiectasis Respiratory 0.976 0.89 – 1.07 0.612 549 5453 all phecode
497 Bronchitis Respiratory 1.07 1.02 – 1.12 0.0105 1946 18824 all phecode
498 Acute bronchospasm Respiratory 1.24 1.12 – 1.37 2.27e-05 496 4943 all phecode
499 Cystic fibrosis Respiratory 1.06 0.888 – 1.25 0.538 151 1510 all phecode
500 Lung disease due to external agents Respiratory 1.1 1.01 – 1.21 0.0341 557 5551 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.996 0.8 – 1.24 0.972 92 920 all phecode
500.2 Pneumoconiosis Respiratory 1.06 0.835 – 1.35 0.627 78 764 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.1 1.01 – 1.2 0.0323 634 6225 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.03 0.954 – 1.11 0.449 815 8076 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.2 1.12 – 1.3 1.18e-06 835 8243 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.04 0.947 – 1.13 0.44 595 5878 all phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 0.951 0.842 – 1.07 0.42 311 3084 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.12 1.06 – 1.18 5.39e-05 1638 15749 all phecode
506 Empyema and pneumothorax Respiratory 1.07 1.03 – 1.11 0.00107 2894 25235 all phecode
507 Pleurisy; pleural effusion Respiratory 1.11 1.06 – 1.15 6.7e-07 2916 26208 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.1 1.05 – 1.15 2.24e-05 2382 22588 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.12 1.09 – 1.16 3.97e-11 4032 29477 all phecode
509.1 Respiratory failure Respiratory 1.15 1.1 – 1.21 1.48e-08 1937 18949 all phecode
509.2 Respiratory insufficiency Respiratory 1.09 1.02 – 1.16 0.00754 1174 11679 all phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.09 1.04 – 1.15 0.00103 1689 16489 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.17 1.11 – 1.23 5.33e-09 1741 17249 all phecode
510 Other diseases of lung Respiratory 1.04 1.01 – 1.07 0.0129 5503 35907 all phecode
510.2 Lung transplant Respiratory 0.966 0.822 – 1.13 0.67 176 1757 all phecode
512 Other symptoms of respiratory system Respiratory 1.07 1.05 – 1.09 2.2e-12 18621 28154 all phecode
512.1 Wheezing Respiratory 1.19 1.12 – 1.26 6.77e-09 1409 13516 all phecode
512.2 Painful respiration Respiratory 1.04 0.99 – 1.08 0.131 2309 21263 all phecode
512.3 Abnormal chest sounds Respiratory 1.01 0.893 – 1.14 0.873 291 2845 all phecode
512.7 Shortness of breath Respiratory 1.12 1.09 – 1.15 5.24e-20 10034 28081 all phecode
512.8 Cough Respiratory 1.07 1.04 – 1.1 1.6e-07 9501 28148 all phecode
512.9 Other dyspnea Respiratory 1.1 1.07 – 1.12 1.55e-14 10804 28104 all phecode
513 Respiratory abnormalities Respiratory 1.1 1.08 – 1.13 1.49e-19 12932 33822 all phecode
513.3 Hypoventilation Respiratory 1.18 1.1 – 1.27 6.96e-06 880 8646 all phecode
513.31 Apnea Respiratory 1.12 1.01 – 1.23 0.0303 462 4607 all phecode
513.32 Orthopnea Respiratory 1.15 0.992 – 1.33 0.0645 220 2160 all phecode
513.4 Hyperventilation Respiratory 1.21 1.1 – 1.33 0.000134 515 5124 all phecode
513.8 Disorders of diaphragm Respiratory 1.03 0.901 – 1.18 0.652 258 2557 all phecode
514 Abnormal findings examination of lungs Respiratory 1.04 1.01 – 1.07 0.0206 5365 34834 all phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 0.924 0.809 – 1.06 0.244 258 2580 all phecode
514.2 Solitary pulmonary nodule Respiratory 1.03 0.987 – 1.07 0.196 3018 27338 all phecode
516 Abnormal sputum Respiratory 1.14 1.05 – 1.23 0.00169 735 7332 all phecode
516.1 Hemoptysis Respiratory 1.14 1.05 – 1.25 0.0029 611 6080 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.06 1.03 – 1.09 1.26e-05 6458 39057 all phecode
519.1 Tracheostomy complications Respiratory 1.23 1.06 – 1.42 0.00503 214 2136 all phecode
519.2 Respiratory complications Respiratory 1.03 0.934 – 1.14 0.523 445 4430 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.01 0.958 – 1.07 0.689 1588 15787 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.08 1.04 – 1.11 9.82e-06 4706 34489 all phecode
520 Disorders of tooth development Digestive 1.01 0.903 – 1.12 0.895 369 3690 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.12 0.95 – 1.32 0.178 165 1642 all phecode
520.2 Disturbances in tooth eruption Digestive 0.961 0.836 – 1.1 0.574 218 2172 all phecode
521 Diseases of hard tissues of teeth Digestive 1.18 1.1 – 1.27 3.78e-06 898 8954 all phecode
521.1 Dental caries Digestive 1.19 1.11 – 1.28 1.73e-06 837 8349 all phecode
521.2 Dental abrasion, erosion and attrition Digestive 1.19 0.889 – 1.6 0.239 52 510 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.2 1.1 – 1.32 7.89e-05 535 5340 all phecode
522.5 Periapical abscess Digestive 1.22 1.11 – 1.35 7.05e-05 459 4583 all phecode
523 Gingival and periodontal diseases Digestive 1.16 1.07 – 1.25 0.000234 718 7180 all phecode
523.1 Gingivitis Digestive 1.08 0.908 – 1.29 0.373 142 1418 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.21 1.08 – 1.35 0.000738 364 3636 all phecode
523.31 Acute periodontitis Digestive 1.19 1.06 – 1.34 0.00377 311 3109 all phecode
523.32 Chronic periodontitis Digestive 1.23 1.02 – 1.5 0.0343 122 1204 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.8 0.713 – 0.898 0.000145 363 3630 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.774 0.67 – 0.894 0.000509 220 2200 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.15 1.07 – 1.23 5.22e-05 1039 10382 all phecode
525.1 Loss of teeth or edentulism Digestive 1.15 1.03 – 1.28 0.0142 374 3731 all phecode
526 Diseases of the jaws Digestive 0.931 0.893 – 0.97 0.000751 2680 26455 all phecode
526.1 Cysts of the jaws Digestive 0.827 0.723 – 0.946 0.00572 247 2470 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.749 0.651 – 0.862 5.57e-05 241 2383 all phecode
526.4 Temporomandibular joint disorders Digestive 0.926 0.876 – 0.979 0.00698 1504 15025 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.927 0.871 – 0.986 0.0167 1187 11858 all phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 0.886 0.818 – 0.958 0.00255 741 7400 all phecode
526.5 Inflammatory conditions of jaw Digestive 1.01 0.893 – 1.14 0.862 287 2864 all phecode
526.8 Exostosis of jaw Digestive 1.02 0.756 – 1.37 0.904 53 521 all phecode
526.9 Jaw disease NOS Digestive 0.951 0.863 – 1.05 0.314 487 4867 all phecode
527 Diseases of the salivary glands Digestive 1.01 0.964 – 1.07 0.592 1781 17771 all phecode
527.1 Hypertrophy of salivary gland Digestive 0.946 0.723 – 1.24 0.686 58 579 all phecode
527.2 Sialoadenitis Digestive 1.05 0.937 – 1.17 0.425 394 3936 all phecode
527.7 Disturbance of salivary secretion Digestive 1 0.937 – 1.08 0.911 952 9481 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.12 0.973 – 1.28 0.117 254 2540 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.971 0.931 – 1.01 0.178 2643 26197 all phecode
528.1 Stomatitis and mucositis Digestive 0.964 0.887 – 1.05 0.393 668 6657 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.08 0.928 – 1.25 0.331 211 2110 all phecode
528.12 Oral aphthae Digestive 0.997 0.861 – 1.15 0.968 215 2137 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.18 1.03 – 1.36 0.0174 235 2338 all phecode
528.4 Cysts of oral soft tissues Digestive 0.738 0.609 – 0.893 0.00181 124 1229 all phecode
528.41 Cyst of the salivary gland Digestive 0.831 0.653 – 1.06 0.132 77 760 all phecode
528.5 Diseases of lips Digestive 0.986 0.891 – 1.09 0.777 462 4602 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.04 0.867 – 1.26 0.647 137 1370 all phecode
528.7 Sialolithiasis Digestive 1.05 0.882 – 1.24 0.605 163 1623 all phecode
529 Diseases and other conditions of the tongue Digestive 1.08 0.992 – 1.17 0.0761 690 6878 all phecode
529.1 Glossitis Digestive 1.15 0.946 – 1.39 0.165 129 1281 all phecode
529.6 Glossodynia Digestive 1.13 0.957 – 1.32 0.154 168 1652 all phecode
530 Diseases of esophagus Digestive 1.1 1.08 – 1.13 4.22e-21 17081 27931 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.1 1.08 – 1.13 5.95e-21 16572 27931 all phecode
530.11 GERD Digestive 1.11 1.08 – 1.13 1.76e-21 16143 27929 all phecode
530.12 Ulcer of esophagus Digestive 1.06 0.954 – 1.18 0.272 400 3983 all phecode
530.13 Barrett's esophagus Digestive 1.17 1.08 – 1.26 0.000116 762 7584 all phecode
530.14 Reflux esophagitis Digestive 1.06 1 – 1.11 0.0319 1900 17495 all phecode
530.15 Eosinophilic esophagitis Digestive 1.01 0.877 – 1.17 0.849 221 2210 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.09 0.999 – 1.18 0.0527 651 6473 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.09 1.01 – 1.17 0.0221 911 8971 all phecode
530.5 Disorders of esophageal motility Digestive 1.09 0.993 – 1.19 0.0706 548 5432 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.874 0.724 – 1.05 0.158 129 1265 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.01 0.805 – 1.28 0.901 82 812 all phecode
530.9 Heartburn Digestive 1.07 1.02 – 1.14 0.0126 1519 14928 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.09 1.04 – 1.15 0.00016 2073 20617 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.03 0.923 – 1.15 0.606 391 3883 all phecode
531.2 Gastric ulcer Digestive 1.13 1.06 – 1.2 0.000172 1201 11970 all phecode
531.3 Duodenal ulcer Digestive 1.03 0.93 – 1.13 0.594 467 4640 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.06 0.982 – 1.15 0.134 804 8018 all phecode
531.5 Gastrojejunal ulcer Digestive 1.25 1.05 – 1.49 0.0141 150 1500 all phecode
532 Dysphagia Digestive 1.09 1.06 – 1.13 1.14e-08 5585 26852 all phecode
535 Gastritis and duodenitis Digestive 1.07 1.02 – 1.11 0.00212 2799 27335 all phecode
535.1 Acute gastritis Digestive 1.14 1.08 – 1.22 2.22e-05 1178 11750 all phecode
535.2 Atrophic gastritis Digestive 0.959 0.853 – 1.08 0.483 344 3413 all phecode
535.6 Duodenitis Digestive 0.999 0.888 – 1.12 0.98 334 3337 all phecode
535.8 Other specified gastritis Digestive 0.991 0.91 – 1.08 0.828 638 6354 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.997 0.938 – 1.06 0.916 1255 12511 all phecode
536 Disorders of function of stomach Digestive 1.02 0.976 – 1.06 0.448 2911 27685 all phecode
536.3 Gastroparesis Digestive 1.06 0.978 – 1.15 0.155 706 6901 all phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.03 0.93 – 1.15 0.547 407 4059 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1 0.956 – 1.05 0.955 2150 21094 all phecode
537 Other disorders of stomach and duodenum Digestive 1.08 1.04 – 1.12 0.000183 3183 30048 all phecode
537.1 Lesions of stomach and duodenum Digestive 1.08 0.918 – 1.26 0.364 173 1725 all phecode
539 Bariatric surgery Digestive 1.71 1.61 – 1.81 7.13e-75 1509 15074 all phecode
540 Appendiceal conditions Digestive 1.01 0.915 – 1.11 0.848 495 4948 all phecode
540.1 Appendicitis Digestive 0.979 0.88 – 1.09 0.691 425 4239 all phecode
540.11 Acute appendicitis Digestive 0.941 0.838 – 1.06 0.307 353 3511 all phecode
550 Abdominal hernia Digestive 1.04 1.01 – 1.07 0.00311 6768 37731 all phecode
550.1 Inguinal hernia Digestive 0.83 0.788 – 0.874 1.61e-12 1744 16488 all phecode
550.2 Diaphragmatic hernia Digestive 1.06 1.02 – 1.11 0.00283 2817 25849 all phecode
550.3 Femoral hernia Digestive 0.769 0.638 – 0.928 0.006 131 1291 all phecode
550.4 Umbilical hernia Digestive 1.04 0.978 – 1.1 0.217 1313 13110 all phecode
550.5 Ventral hernia Digestive 1.18 1.12 – 1.23 2.92e-12 2241 22163 all phecode
550.6 Incisional hernia Digestive 1.18 1.11 – 1.26 3.08e-08 1313 13111 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.07 1.01 – 1.13 0.0136 1536 15153 all phecode
555.1 Regional enteritis Digestive 1.11 1.03 – 1.19 0.00419 919 9095 all phecode
555.2 Ulcerative colitis Digestive 0.994 0.926 – 1.07 0.862 937 9315 all phecode
555.21 Ulcerative colitis (chronic) Digestive 0.942 0.859 – 1.03 0.213 537 5315 all phecode
556 Ulceration of the lower GI tract Digestive 1.11 1.02 – 1.21 0.016 632 6267 all phecode
556.1 Ulceration of intestine Digestive 1.1 1 – 1.2 0.0501 551 5451 all phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 1.01 0.871 – 1.17 0.907 214 2093 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.22 1.15 – 1.28 2.05e-13 1716 16490 all phecode
557.1 Celiac disease Digestive 0.973 0.876 – 1.08 0.604 421 4026 all phecode
558 Noninfectious gastroenteritis Digestive 1.07 1.03 – 1.11 0.00062 3458 26408 all phecode
559 Ileostomy status Digestive 1.09 1.02 – 1.17 0.0165 957 9565 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.05 1.01 – 1.1 0.00872 3004 24851 all phecode
560.1 Paralytic ileus Digestive 1.05 0.992 – 1.1 0.099 1627 15714 all phecode
560.2 Impaction of intestine Digestive 1.04 0.929 – 1.16 0.52 387 3779 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.959 0.84 – 1.09 0.536 266 2647 all phecode
560.4 Other intestinal obstruction Digestive 1.06 1.01 – 1.12 0.0304 1651 16170 all phecode
561 Symptoms involving digestive system Digestive 1.03 0.986 – 1.07 0.187 2608 21766 all phecode
562 Diverticulosis and diverticulitis Digestive 1.02 0.992 – 1.05 0.149 6295 23431 all phecode
562.1 Diverticulosis Digestive 1.02 0.992 – 1.05 0.152 6246 23383 all phecode
562.2 Diverticulitis Digestive 1.05 0.991 – 1.1 0.103 1611 15162 all phecode
564 Functional digestive disorders Digestive 1.06 1.04 – 1.09 5.74e-07 11411 28676 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.03 0.993 – 1.07 0.112 3457 22266 all phecode
564.9 Personal history of diseases of digestive system Digestive 1.08 1.04 – 1.12 0.000148 3074 25861 all phecode
565 Anal and rectal conditions Digestive 0.984 0.947 – 1.02 0.388 3355 30757 all phecode
565.1 Anal and rectal polyp Digestive 0.98 0.923 – 1.04 0.498 1305 12649 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.14 1.08 – 1.21 9.79e-06 1364 13616 all phecode
568 Other disorders of peritoneum Digestive 1.14 1.09 – 1.21 3.98e-07 1705 17038 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.18 1.11 – 1.25 1.03e-07 1247 12468 all phecode
569 Other disorders of intestine Digestive 1.06 1.03 – 1.08 2.56e-05 8079 35231 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.11 0.984 – 1.25 0.0911 326 3260 all phecode
569.2 Gastrointestinal complications Digestive 1.18 1.11 – 1.25 1.8e-08 1395 13933 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.12 1.08 – 1.16 1.07e-11 4610 32562 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.12 1.08 – 1.16 1.56e-11 4342 32234 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.08 1.01 – 1.16 0.0177 1018 10095 all phecode
571.6 Primary biliary cirrhosis Digestive 1.03 0.875 – 1.2 0.758 179 1790 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.09 1.02 – 1.17 0.0144 950 9498 all phecode
571.81 Portal hypertension Digestive 1.05 0.964 – 1.15 0.248 573 5730 all phecode
572 Ascites (non malignant) Digestive 1.06 1.01 – 1.11 0.0103 2278 22675 all phecode
573 Other disorders of liver Digestive 1.07 1.04 – 1.11 2.52e-06 5599 33620 all phecode
573.1 Chronic passive congestion of liver Digestive 1.34 1.12 – 1.61 0.00172 136 1359 all phecode
573.2 Liver replaced by transplant Digestive 1.07 0.938 – 1.21 0.33 292 2920 all phecode
573.3 Hepatomegaly Digestive 1.11 1.01 – 1.23 0.0317 470 4700 all phecode
573.4 Acute and subacute necrosis of liver Digestive 0.979 0.867 – 1.11 0.727 316 3149 all phecode
573.5 Jaundice (not of newborn) Digestive 1.06 0.987 – 1.13 0.114 958 9496 all phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.04 0.996 – 1.08 0.0735 2756 26470 all phecode
573.7 Abnormal results of function study of liver Digestive 1.03 0.986 – 1.07 0.205 3018 27774 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.03 0.997 – 1.06 0.0734 4679 33866 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.1 1.06 – 1.14 1.24e-06 3177 30809 all phecode
574.1 Cholelithiasis Digestive 1.09 1.05 – 1.14 1.08e-05 2924 28874 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.19 1.06 – 1.34 0.00311 342 3412 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.06 0.968 – 1.16 0.209 553 5501 all phecode
574.2 Calculus of bile duct Digestive 1.01 0.935 – 1.08 0.858 852 8503 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.14 1.06 – 1.23 0.000569 822 8181 all phecode
575 Other biliary tract disease Digestive 1.04 0.998 – 1.09 0.0612 2266 22555 all phecode
575.1 Cholangitis Digestive 0.987 0.881 – 1.11 0.824 354 3530 all phecode
575.2 Obstruction of bile duct Digestive 1.12 1.03 – 1.22 0.0082 621 6201 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.954 0.825 – 1.1 0.527 207 2063 all phecode
575.7 Other disorders of gallbladder Digestive 1.02 0.952 – 1.1 0.555 939 9382 all phecode
575.8 Other disorders of biliary tract Digestive 1.05 0.985 – 1.12 0.132 1154 11523 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.02 0.892 – 1.16 0.784 260 2600 all phecode
577 Diseases of pancreas Digestive 1.05 1 – 1.1 0.0371 2225 22106 all phecode
577.1 Acute pancreatitis Digestive 1.1 1.03 – 1.17 0.00297 1212 12110 all phecode
577.2 Chronic pancreatitis Digestive 1.18 1.07 – 1.3 0.00118 495 4950 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.01 0.919 – 1.11 0.866 570 5601 all phecode
578 Gastrointestinal hemorrhage Digestive 1.03 0.993 – 1.06 0.127 4554 37045 all phecode
578.1 Hematemesis Digestive 1.09 0.99 – 1.2 0.0782 485 4842 all phecode
578.2 Blood in stool Digestive 1.05 1.01 – 1.09 0.0223 2743 26554 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.01 0.96 – 1.05 0.828 2210 21750 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.05 0.997 – 1.11 0.0618 1562 15345 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.1 1.06 – 1.13 6.14e-08 4431 34209 all phecode
579.2 Splenomegaly Digestive 1.14 1.05 – 1.23 0.00143 730 7262 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.03 0.973 – 1.09 0.3 1410 13877 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.22 1.16 – 1.29 2.26e-14 1881 15516 all phecode
580.1 Glomerulonephritis Genitourinary 1.27 1.14 – 1.42 2.1e-05 401 3992 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.2 1 – 1.43 0.0475 146 1440 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.57 1.29 – 1.93 1.11e-05 114 1128 all phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.11 0.846 – 1.45 0.455 61 600 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.34 1.17 – 1.53 1.86e-05 277 2760 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.23 1.07 – 1.41 0.00417 221 2193 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.24 1.17 – 1.31 7.87e-13 1502 11930 all phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.3 1.21 – 1.4 1.38e-12 992 7228 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.16 1.07 – 1.26 0.000341 683 6612 all phecode
580.4 Renal sclerosis, NOS Genitourinary 1.19 1.05 – 1.33 0.00446 340 3400 all phecode
585 Renal failure Genitourinary 1.16 1.13 – 1.19 7.22e-27 7470 32340 all phecode
585.1 Acute renal failure Genitourinary 1.18 1.14 – 1.22 4.74e-21 4265 27230 all phecode
585.2 Renal failure NOS Genitourinary 1.21 1.12 – 1.31 6.04e-07 832 8162 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.18 1.15 – 1.22 2.16e-26 5580 29470 all phecode
585.31 Renal dialysis Genitourinary 1.18 1.09 – 1.27 6.87e-05 747 7423 all phecode
585.32 End stage renal disease Genitourinary 1.25 1.17 – 1.34 1.54e-10 1007 9783 all phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.22 1.17 – 1.27 1.68e-21 3209 21312 all phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.26 1.17 – 1.35 1.24e-10 977 9190 all phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.17 1.1 – 1.25 5.53e-07 1227 11191 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.1 1.07 – 1.13 1e-12 7628 34189 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.12 0.997 – 1.25 0.0557 349 3480 all phecode
586.11 Small kidney Genitourinary 1.17 1.01 – 1.36 0.0313 210 2093 all phecode
586.12 Vesicoureteral reflux Genitourinary 1.06 0.884 – 1.28 0.514 136 1360 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.02 0.96 – 1.08 0.558 1381 12912 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.19 1.02 – 1.39 0.0299 187 1862 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.02 0.974 – 1.08 0.344 1821 17115 all phecode
587 Kidney replaced by transpant Genitourinary 1.15 1.07 – 1.24 0.000251 819 8134 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.22 1.13 – 1.31 4.08e-08 976 9389 all phecode
588.1 Renal osteodystrophy Genitourinary 1.15 1.01 – 1.31 0.0324 290 2900 all phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.22 1.13 – 1.33 9.12e-07 755 7275 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.17 1.09 – 1.25 8.28e-06 1007 9834 all phecode
590 Pyelonephritis Genitourinary 1.12 1.06 – 1.18 7.8e-05 1461 14350 all phecode
591 Urinary tract infection Genitourinary 1.03 1.01 – 1.06 0.0147 9873 32513 all phecode
592 Cystitis and urethritis Genitourinary 1.01 0.967 – 1.05 0.752 3038 24207 all phecode
592.1 Cystitis Genitourinary 1.01 0.971 – 1.05 0.584 2880 23279 all phecode
592.11 Acute cystitis Genitourinary 1.01 0.959 – 1.06 0.719 1783 16452 all phecode
592.12 Chronic cystitis Genitourinary 0.972 0.847 – 1.12 0.692 239 2343 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.952 0.858 – 1.06 0.357 431 4310 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.964 0.83 – 1.12 0.629 210 2093 all phecode
593 Hematuria Genitourinary 1.03 0.999 – 1.06 0.0588 4859 32063 all phecode
593.1 Gross hematuria Genitourinary 1.05 0.997 – 1.11 0.0639 1585 14824 all phecode
593.2 Microscopic hematuria Genitourinary 1.01 0.949 – 1.08 0.664 1049 10301 all phecode
594 Urinary calculus Genitourinary 1.08 1.05 – 1.11 4.76e-08 6707 38209 all phecode
594.1 Calculus of kidney Genitourinary 1.08 1.05 – 1.11 5.22e-08 6273 38051 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.08 0.969 – 1.21 0.158 366 3638 all phecode
594.3 Calculus of ureter Genitourinary 1.05 0.995 – 1.12 0.0752 1361 13561 all phecode
594.8 Renal colic Genitourinary 1.09 0.973 – 1.22 0.136 356 3560 all phecode
595 Hydronephrosis Genitourinary 1.06 1.01 – 1.12 0.0233 1670 16658 all phecode
596 Other disorders of bladder Genitourinary 0.999 0.961 – 1.04 0.972 3074 28020 all phecode
596.1 Bladder neck obstruction Genitourinary 1.03 0.927 – 1.15 0.551 400 3942 all phecode
596.5 Functional disorders of bladder Genitourinary 0.994 0.944 – 1.05 0.82 1719 17049 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.98 0.922 – 1.04 0.529 1211 11998 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.967 0.89 – 1.05 0.424 661 6537 all phecode
597.2 Urinary complications NEC Genitourinary 1.01 0.942 – 1.08 0.855 1049 10479 all phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.07 0.915 – 1.25 0.4 189 1873 all phecode
598 Abnormal findings on examination of urine Genitourinary 1 0.835 – 1.2 0.997 138 1356 all phecode
598.4 Other cells and casts in urine Genitourinary 0.993 0.818 – 1.2 0.94 122 1192 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1 0.981 – 1.02 0.816 14168 30681 all phecode
599.1 Urinary obstruction Genitourinary 0.86 0.793 – 0.932 0.000248 728 6861 all phecode
599.2 Retention of urine Genitourinary 1 0.971 – 1.04 0.858 5034 28305 all phecode
599.3 Dysuria Genitourinary 0.994 0.961 – 1.03 0.724 4397 27849 all phecode
599.4 Urinary incontinence Genitourinary 1.03 0.994 – 1.06 0.109 5599 26960 all phecode
599.5 Frequency of urination and polyuria Genitourinary 0.972 0.942 – 1 0.0664 5498 28723 all phecode
599.6 Oliguria and anuria Genitourinary 1.12 1.03 – 1.23 0.0111 599 5902 all phecode
599.7 Urethral discharge Genitourinary 1.04 0.859 – 1.27 0.663 118 1175 all phecode
599.8 Other symptoms involving urinary system Genitourinary 0.993 0.963 – 1.02 0.661 5446 27963 all phecode
599.9 Other abnormality of urination Genitourinary 0.971 0.933 – 1.01 0.144 3041 24877 all phecode
600 Hyperplasia of prostate Genitourinary 0.927 0.891 – 0.964 0.000185 4063 11364 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.968 0.906 – 1.04 0.342 1044 9665 all phecode
601.1 Prostatitis Genitourinary 0.855 0.775 – 0.943 0.00179 477 4596 all phecode
601.11 Acute prostatitis Genitourinary 0.933 0.765 – 1.14 0.491 124 1200 all phecode
601.12 Chronic prostatitis Genitourinary 0.886 0.715 – 1.1 0.272 95 943 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.02 0.92 – 1.14 0.657 389 3822 all phecode
601.4 Balanoposthitis Genitourinary 1.04 0.859 – 1.26 0.68 127 1224 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.13 0.959 – 1.34 0.14 161 1591 all phecode
602 Other disorders of prostate Genitourinary 0.885 0.79 – 0.992 0.0356 361 3399 all phecode
602.3 Dysplasia of prostate Genitourinary 1.01 0.786 – 1.29 0.948 77 730 all phecode
603 Other disorders of testis Genitourinary 1.01 0.912 – 1.11 0.879 440 4354 all phecode
603.1 Hydrocele Genitourinary 1.01 0.897 – 1.14 0.84 293 2882 all phecode
603.2 Spermatocele Genitourinary 0.899 0.761 – 1.06 0.206 156 1539 all phecode
604 Disorders of penis Genitourinary 0.966 0.891 – 1.05 0.406 685 6748 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.34 1.13 – 1.58 0.000616 155 1540 all phecode
604.3 Peyronie's disease Genitourinary 0.86 0.743 – 0.995 0.0433 215 2132 all phecode
605 Erectile dysfunction [ED] Genitourinary 0.951 0.915 – 0.988 0.0103 3776 12700 all phecode
608 Other disorders of male genital organs Genitourinary 0.971 0.92 – 1.02 0.274 1645 13758 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.846 0.762 – 0.939 0.00165 424 4196 all phecode
609.1 Infertility, male Genitourinary 0.875 0.774 – 0.99 0.0346 302 2992 all phecode
609.11 Azoospermia and oligospermia Genitourinary 1.12 0.897 – 1.4 0.312 95 950 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.73 0.612 – 0.871 0.000474 154 1519 all phecode
610 Benign mammary dysplasias Genitourinary 0.918 0.883 – 0.953 1e-05 3683 16548 all phecode
610.1 Cystic mastopathy Genitourinary 0.917 0.869 – 0.969 0.00186 1633 14191 all phecode
610.2 Fibroadenosis of breast Genitourinary 0.796 0.602 – 1.05 0.109 60 600 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.903 0.865 – 0.942 2.38e-06 2837 16430 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.907 0.853 – 0.965 0.00195 1269 12191 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.911 0.883 – 0.94 5.08e-09 6067 18690 all phecode
611.1 Abnormal mammogram Genitourinary 0.893 0.863 – 0.924 7.82e-11 4980 16120 all phecode
611.11 Mammographic microcalcification Genitourinary 0.832 0.779 – 0.889 4.78e-08 1122 10394 all phecode
611.3 Lump or mass in breast Genitourinary 0.905 0.871 – 0.94 3.08e-07 3549 18572 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.974 0.911 – 1.04 0.435 1051 10425 all phecode
612.1 Galactorrhea Genitourinary 0.984 0.824 – 1.18 0.862 139 1390 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.03 0.95 – 1.11 0.522 800 7962 all phecode
612.3 Congenital anomalies of breast Genitourinary 0.606 0.471 – 0.778 8.74e-05 83 810 all phecode
613 Other nonmalignant breast conditions Genitourinary 0.965 0.931 – 1 0.0547 3897 22072 all phecode
613.1 Inflammatory disease of breast Genitourinary 0.99 0.907 – 1.08 0.829 593 5874 all phecode
613.5 Mastodynia Genitourinary 0.975 0.924 – 1.03 0.355 1675 16203 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.897 0.834 – 0.965 0.00367 883 8754 all phecode
613.8 Other specified disorders of breast Genitourinary 0.896 0.835 – 0.963 0.00274 932 9248 all phecode
613.9 Breast disorder NOS Genitourinary 0.928 0.877 – 0.982 0.01 1465 14174 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1 0.965 – 1.04 0.957 3715 19647 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1 0.892 – 1.13 0.969 337 3370 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.05 0.947 – 1.15 0.376 478 4773 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.14 0.918 – 1.43 0.229 94 933 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.943 0.804 – 1.11 0.474 186 1842 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.02 0.886 – 1.17 0.821 246 2460 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.1 0.932 – 1.31 0.253 165 1639 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.997 0.958 – 1.04 0.872 3180 19539 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.04 0.908 – 1.19 0.586 264 2640 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.981 0.94 – 1.02 0.37 2732 18924 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.13 0.939 – 1.36 0.194 132 1311 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.19 1.03 – 1.37 0.0218 225 2244 all phecode
615 Endometriosis Genitourinary 1.01 0.958 – 1.07 0.67 1585 14666 all phecode
618 Genital prolapse Genitourinary 0.967 0.921 – 1.01 0.17 2079 17915 all phecode
618.1 Prolapse of vaginal walls Genitourinary 0.924 0.871 – 0.979 0.00748 1408 13456 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.927 0.843 – 1.02 0.113 542 5390 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.932 0.823 – 1.06 0.269 317 3162 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.07 0.964 – 1.19 0.204 441 4394 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.981 0.95 – 1.01 0.221 5728 18687 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1 0.94 – 1.06 0.995 1233 12082 all phecode
619.2 Disorders of uterus, NEC Genitourinary 0.938 0.858 – 1.02 0.157 591 5897 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.931 0.843 – 1.03 0.153 483 4823 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.975 0.933 – 1.02 0.251 2525 18404 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1 0.943 – 1.07 0.891 1189 11717 all phecode
620 Dysplasia of female genital organs Genitourinary 1 0.901 – 1.11 0.97 395 3950 all phecode
620.1 Dysplasia of cervix Genitourinary 1.07 0.911 – 1.25 0.423 178 1780 all phecode
621 Endometrial hyperplasia Genitourinary 1.09 0.984 – 1.21 0.0993 437 4370 all phecode
622 Polyp of female genital organs Genitourinary 0.952 0.899 – 1.01 0.0917 1449 14264 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.979 0.918 – 1.04 0.519 1132 11189 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.88 0.793 – 0.977 0.0162 445 4444 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.02 0.942 – 1.1 0.679 824 8165 all phecode
624 Symptoms involving female genital tract Genitourinary 0.982 0.926 – 1.04 0.535 1348 12518 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.933 0.807 – 1.08 0.351 216 2155 all phecode
624.2 Atrophy of female genital tract Genitourinary 1.18 0.898 – 1.56 0.232 64 615 all phecode
624.9 stress incontinence, female Genitourinary 1.03 0.975 – 1.08 0.33 1935 15408 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.979 0.948 – 1.01 0.191 5653 17303 all phecode
625.1 Dyspareunia Genitourinary 0.948 0.892 – 1.01 0.0867 1267 12474 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1 0.969 – 1.03 0.97 5940 15585 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1 0.967 – 1.04 0.883 4315 14604 all phecode
626.11 Absent or infrequent menstruation Genitourinary 1.02 0.955 – 1.09 0.554 1062 8531 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.02 0.976 – 1.08 0.326 2097 11991 all phecode
626.13 Irregular menstrual cycle Genitourinary 1 0.955 – 1.06 0.849 1957 12265 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.967 0.902 – 1.04 0.34 970 8996 all phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.973 0.875 – 1.08 0.615 394 3789 all phecode
626.2 Dysmenorrhea Genitourinary 1.02 0.964 – 1.08 0.458 1373 9857 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.979 0.87 – 1.1 0.717 336 3308 all phecode
626.8 Infertility, female Genitourinary 0.998 0.925 – 1.08 0.95 817 6741 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.935 0.902 – 0.968 0.000191 4560 14557 all phecode
627.1 Postmenopausal bleeding Genitourinary 0.955 0.894 – 1.02 0.167 1146 10338 all phecode
627.2 Symptomatic menopause Genitourinary 0.915 0.877 – 0.955 3.84e-05 3017 13763 all phecode
627.21 Symptomatic artificial menopause Genitourinary 0.908 0.761 – 1.08 0.287 152 1514 all phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.776 0.689 – 0.874 2.92e-05 356 3513 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.887 0.827 – 0.952 0.000869 997 9484 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.954 0.852 – 1.07 0.418 361 3580 all phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.976 0.865 – 1.1 0.698 309 3082 all phecode
628 Ovarian cyst Genitourinary 1 0.956 – 1.06 0.852 1945 13838 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.996 0.925 – 1.07 0.916 826 8047 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.915 0.805 – 1.04 0.172 273 2715 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.977 0.8 – 1.19 0.816 117 1170 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.869 0.794 – 0.951 0.00236 563 5309 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.865 0.773 – 0.967 0.0107 370 3629 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.831 0.733 – 0.942 0.00394 288 2850 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.924 0.865 – 0.987 0.0187 1080 7870 all phecode
636.1 Threatened premature labor Pregnancy Complications 0.929 0.834 – 1.03 0.181 380 3799 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.926 0.816 – 1.05 0.231 288 2868 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.938 0.847 – 1.04 0.211 441 4365 all phecode
636.8 Cervical incompetence Pregnancy Complications 1.01 0.801 – 1.27 0.934 77 770 all phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.13 0.9 – 1.41 0.298 85 850 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.02 0.932 – 1.11 0.704 585 5725 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.03 0.91 – 1.16 0.665 302 3013 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.12 0.981 – 1.28 0.0934 252 2506 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.12 0.924 – 1.36 0.251 119 1190 all phecode
644 Anemia during pregnancy Pregnancy Complications 1.01 0.874 – 1.16 0.923 224 2224 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.979 0.909 – 1.05 0.579 855 6531 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.929 0.805 – 1.07 0.315 211 2093 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1 0.871 – 1.15 0.968 222 2213 all phecode
647.3 Major puerperal infection Pregnancy Complications 1.19 0.92 – 1.54 0.186 65 650 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.967 0.909 – 1.03 0.283 1275 8010 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.01 0.929 – 1.1 0.801 649 5687 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.983 0.9 – 1.07 0.709 587 5463 all phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1 0.862 – 1.17 0.962 207 2055 all phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 0.898 0.774 – 1.04 0.153 204 2040 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.928 0.878 – 0.98 0.00728 1624 10064 all phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 0.943 0.865 – 1.03 0.185 616 5533 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.986 0.918 – 1.06 0.707 898 7014 all phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 1.01 0.778 – 1.3 0.965 66 660 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.931 0.866 – 1 0.0561 887 6802 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.05 0.919 – 1.21 0.452 236 2351 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.04 0.881 – 1.23 0.629 158 1580 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.855 0.732 – 0.999 0.0484 184 1814 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.14 1.11 – 1.17 1.98e-19 6500 38394 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.04 0.979 – 1.11 0.195 1256 11462 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.14 1.07 – 1.23 9.55e-05 1007 9981 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.17 1.11 – 1.22 1.81e-10 2123 19952 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.16 1.11 – 1.22 6.07e-11 2252 20944 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.17 1.11 – 1.23 7.01e-10 1820 16893 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.2 1.14 – 1.27 4.72e-11 1572 15588 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.09 1.04 – 1.14 0.000394 2257 21750 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.09 0.997 – 1.2 0.0585 558 5504 all phecode
686.2 Impetigo Dermatologic 1.07 0.96 – 1.19 0.225 414 4117 all phecode
686.3 Pilonidal cyst Dermatologic 1.03 0.871 – 1.22 0.727 160 1594 all phecode
686.4 Pyogenic granuloma Dermatologic 0.973 0.823 – 1.15 0.748 158 1570 all phecode
686.5 Pyoderma Dermatologic 1.28 0.968 – 1.69 0.0838 63 630 all phecode
687 Symptoms affecting skin Dermatologic 0.99 0.939 – 1.04 0.696 1690 16343 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.99 0.964 – 1.02 0.49 7007 34623 all phecode
687.3 Changes in skin texture Dermatologic 1.12 1.01 – 1.25 0.0317 415 4121 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.05 1.02 – 1.08 0.00119 6375 34216 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.934 0.912 – 0.957 4.19e-08 9311 37335 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.906 0.878 – 0.935 7.64e-10 5184 31581 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.906 0.878 – 0.935 7.22e-10 5174 31553 all phecode
691 Congenital anomalies of skin Dermatologic 0.985 0.898 – 1.08 0.751 541 5337 all phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 1.15 0.878 – 1.51 0.309 62 613 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.911 0.866 – 0.958 0.000279 1861 17936 all phecode
694.1 Vitiligo Dermatologic 1.05 0.876 – 1.26 0.593 137 1347 all phecode
694.2 Other dyschromia Dermatologic 0.899 0.853 – 0.948 8.83e-05 1674 16183 all phecode
694.3 Vascular disorders of skin Dermatologic 1.07 0.845 – 1.37 0.558 82 819 all phecode
695 Erythematous conditions Dermatologic 1.01 0.981 – 1.05 0.399 4120 30247 all phecode
695.1 Toxic erythema Dermatologic 1.14 0.888 – 1.47 0.301 70 688 all phecode
695.2 Bullous dermatoses Dermatologic 1.06 0.834 – 1.35 0.626 85 805 all phecode
695.3 Rosacea Dermatologic 0.899 0.855 – 0.947 4.71e-05 1816 17663 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.05 0.966 – 1.14 0.257 672 6686 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.09 0.949 – 1.25 0.228 247 2437 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.04 0.956 – 1.13 0.351 637 6337 all phecode
695.7 Prurigo and Lichen Dermatologic 0.976 0.894 – 1.07 0.595 605 5986 all phecode
695.8 Other specified erythematous conditions Dermatologic 1.12 1.03 – 1.2 0.0048 812 7980 all phecode
695.81 Erythema nodosum Dermatologic 0.902 0.675 – 1.2 0.481 55 550 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.15 1.06 – 1.25 0.00117 679 6756 all phecode
696 Psoriasis and related disorders Dermatologic 1.03 0.972 – 1.09 0.33 1401 13832 all phecode
696.3 Pityriasis Dermatologic 0.856 0.691 – 1.06 0.155 92 904 all phecode
696.4 Psoriasis Dermatologic 1.05 0.993 – 1.12 0.0824 1311 12976 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.05 0.983 – 1.11 0.157 1200 11867 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.02 0.894 – 1.16 0.794 282 2810 all phecode
697 Sarcoidosis Dermatologic 1.07 0.956 – 1.21 0.232 333 3330 all phecode
698 Pruritus and related conditions Dermatologic 0.984 0.94 – 1.03 0.5 2254 21889 all phecode
700 Corns and callosities Dermatologic 1.05 0.994 – 1.12 0.0804 1373 10894 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.99 0.964 – 1.02 0.439 7651 38050 all phecode
701.1 Keratoderma, acquired Dermatologic 1.02 0.936 – 1.12 0.602 567 5524 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.925 0.883 – 0.969 0.000976 2184 21550 all phecode
701.3 Circumscribed scleroderma Dermatologic 0.951 0.868 – 1.04 0.275 571 5660 all phecode
701.4 Keloid scar Dermatologic 0.922 0.843 – 1.01 0.0774 578 5716 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.06 0.95 – 1.18 0.311 400 3982 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.889 0.864 – 0.914 2.74e-16 6956 29525 all phecode
702.1 Actinic keratosis Dermatologic 0.857 0.827 – 0.888 6.07e-18 4171 26529 all phecode
702.2 Seborrheic keratosis Dermatologic 0.882 0.855 – 0.909 1.13e-15 5480 31552 all phecode
702.4 Degenerative skin disorders Dermatologic 1.13 0.902 – 1.42 0.285 86 832 all phecode
703 Diseases of nail, NOS Dermatologic 1.03 0.972 – 1.08 0.357 1650 14562 all phecode
703.1 Ingrowing nail Dermatologic 1.04 0.965 – 1.11 0.326 920 8597 all phecode
704 Diseases of hair and hair follicles Dermatologic 0.966 0.929 – 1 0.0828 3118 29542 all phecode
704.1 Alopecia Dermatologic 0.935 0.882 – 0.991 0.0232 1408 13871 all phecode
704.11 Alopecia Areata Dermatologic 0.943 0.742 – 1.2 0.631 82 811 all phecode
704.12 Telogen effluvium Dermatologic 0.822 0.628 – 1.08 0.155 63 615 all phecode
704.2 Hirsutism Dermatologic 1.31 1.16 – 1.49 1.96e-05 299 2946 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.968 0.919 – 1.02 0.215 1752 17189 all phecode
705 Disorders of sweat glands Dermatologic 1.19 1.09 – 1.29 0.000132 603 6012 all phecode
705.1 Dyshidrosis Dermatologic 0.983 0.825 – 1.17 0.851 154 1540 all phecode
705.3 Hidradenitis Dermatologic 1.39 1.21 – 1.59 3.63e-06 245 2440 all phecode
705.8 Hyperhidrosis Dermatologic 0.999 0.937 – 1.07 0.983 1112 10986 all phecode
706 Diseases of sebaceous glands Dermatologic 0.926 0.9 – 0.953 1.44e-07 5995 39748 all phecode
706.1 Acne Dermatologic 0.869 0.833 – 0.907 1.13e-10 2594 22570 all phecode
706.2 Sebaceous cyst Dermatologic 0.931 0.894 – 0.97 0.000615 2814 26819 all phecode
706.3 Seborrhea Dermatologic 0.839 0.635 – 1.11 0.215 59 582 all phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.981 0.93 – 1.03 0.479 1684 15289 all phecode
707 Chronic ulcer of skin Dermatologic 1.16 1.12 – 1.21 3.62e-13 2871 26816 all phecode
707.1 Decubitus ulcer Dermatologic 1.14 1.06 – 1.23 0.000471 825 8119 all phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.25 1.17 – 1.33 3.17e-11 1108 9992 all phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1.14 1.08 – 1.2 2.51e-06 1641 16172 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.99 0.936 – 1.05 0.734 1477 14427 all phecode
709.2 Sicca syndrome Dermatologic 1 0.91 – 1.1 0.961 505 4986 all phecode
709.3 Systemic sclerosis Dermatologic 0.817 0.707 – 0.943 0.00587 224 2209 all phecode
709.5 Dermatomyositis Dermatologic 1.12 0.901 – 1.39 0.307 92 892 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.98 0.775 – 1.24 0.865 90 892 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.01 0.941 – 1.09 0.761 917 9089 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.18 1.11 – 1.25 2.54e-07 1254 12103 all phecode
710.1 Osteomyelitis Musculoskeletal 1.17 1.1 – 1.24 1.15e-06 1203 11636 all phecode
710.11 Acute osteomyelitis Musculoskeletal 1.33 1.21 – 1.45 1.15e-09 590 5708 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.21 1.1 – 1.33 9.13e-05 531 5163 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.18 1.11 – 1.26 5.23e-07 1153 11149 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.02 0.912 – 1.13 0.769 410 4099 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.11 0.98 – 1.27 0.0981 290 2900 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.22 1.03 – 1.44 0.0199 178 1776 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.16 1.03 – 1.31 0.0164 314 3028 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.22 1.04 – 1.43 0.0139 194 1824 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.12 1.06 – 1.17 7.48e-06 2086 18159 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.15 1.09 – 1.21 6.51e-07 1670 15087 all phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.01 0.788 – 1.3 0.933 77 767 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.11 1.04 – 1.18 0.00167 1209 11967 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.15 1.01 – 1.31 0.0372 262 2611 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.24 1.07 – 1.43 0.00471 219 2182 all phecode
716 Other arthropathies Musculoskeletal 1.11 1.08 – 1.13 4.22e-20 13482 31305 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.13 0.962 – 1.32 0.14 192 1920 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.897 0.743 – 1.08 0.26 131 1293 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.11 1.09 – 1.13 2.75e-20 13410 31294 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.91 0.797 – 1.04 0.163 261 2565 all phecode
720 Spinal stenosis Musculoskeletal 1.09 1.05 – 1.13 1.17e-06 3958 28539 all phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1.11 1.06 – 1.15 1.26e-06 2872 23656 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1.05 1.02 – 1.08 0.00344 5509 32391 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.04 1.01 – 1.08 0.00956 5153 31896 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.09 1.01 – 1.17 0.0202 867 8629 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.22 1.07 – 1.4 0.00265 262 2600 all phecode
722 Intervertebral disc disorders Musculoskeletal 1.08 1.05 – 1.11 1.54e-07 6284 34317 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.06 1.02 – 1.1 0.00123 3591 31411 all phecode
722.3 Schmorl's nodes Musculoskeletal 1.04 0.86 – 1.27 0.662 126 1248 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.07 1.03 – 1.11 0.000138 3957 30744 all phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.08 0.98 – 1.19 0.124 515 5140 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.06 0.951 – 1.18 0.29 397 3968 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.07 1.02 – 1.12 0.0084 1932 19288 all phecode
723 Other disorders of cervical region Musculoskeletal 0.972 0.907 – 1.04 0.423 952 9495 all phecode
723.1 Torticollis Musculoskeletal 0.951 0.833 – 1.09 0.458 254 2522 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.03 0.999 – 1.07 0.0569 4130 31954 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.03 0.988 – 1.08 0.157 2307 21902 all phecode
724.2 Disorders of coccyx Musculoskeletal 0.983 0.885 – 1.09 0.755 426 4215 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.1 1.02 – 1.18 0.0122 931 9295 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.05 0.987 – 1.11 0.128 1412 14087 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.975 0.951 – 0.998 0.0365 9917 30176 all phecode
726.1 Enthesopathy Musculoskeletal 0.968 0.943 – 0.995 0.0187 7507 30106 all phecode
726.2 Synoviopathy Musculoskeletal 0.969 0.906 – 1.04 0.362 1015 9987 all phecode
726.3 Bursitis Musculoskeletal 0.957 0.909 – 1.01 0.088 1829 16722 all phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.982 0.922 – 1.05 0.565 1193 11485 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.992 0.966 – 1.02 0.564 7425 30105 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1 0.961 – 1.04 0.99 3092 24998 all phecode
727.2 Bursitis disorders Musculoskeletal 0.988 0.888 – 1.1 0.832 419 4112 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.954 0.9 – 1.01 0.107 1400 13621 all phecode
727.5 Rupture of synovium Musculoskeletal 1.12 1.01 – 1.24 0.0253 480 4672 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.961 0.92 – 1 0.0804 2461 21948 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.993 0.91 – 1.08 0.882 591 5893 all phecode
727.8 Plica syndrome Musculoskeletal 0.9 0.75 – 1.08 0.259 130 1264 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.02 0.987 – 1.05 0.244 4546 29473 all phecode
728.1 Muscular calcification and ossification Musculoskeletal 0.942 0.75 – 1.18 0.608 85 843 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.914 0.809 – 1.03 0.152 297 2949 all phecode
728.7 Fasciitis Musculoskeletal 0.971 0.932 – 1.01 0.164 2814 23463 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.808 0.726 – 0.9 9.66e-05 419 4138 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.11 1.07 – 1.15 9.87e-09 3642 27471 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.955 0.746 – 1.22 0.717 74 726 all phecode
729.3 Panniculitis Musculoskeletal 1.25 1.02 – 1.52 0.0308 119 1174 all phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 0.905 0.706 – 1.16 0.431 67 664 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.07 0.926 – 1.24 0.353 210 2091 all phecode
732 Osteochondropathies Musculoskeletal 1.08 0.964 – 1.21 0.186 361 3604 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.18 1.01 – 1.38 0.0327 198 1969 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.929 0.739 – 1.17 0.53 90 882 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.914 0.883 – 0.946 2.17e-07 4543 26941 all phecode
733.2 Cyst of bone Musculoskeletal 0.971 0.833 – 1.13 0.703 190 1900 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.982 0.893 – 1.08 0.701 518 5160 all phecode
733.6 Costochondritis Musculoskeletal 1 0.894 – 1.12 0.973 357 3562 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.05 0.973 – 1.13 0.209 822 8205 all phecode
733.9 Chondromalacia Musculoskeletal 0.97 0.785 – 1.2 0.778 96 960 all phecode
735 Acquired foot deformities Musculoskeletal 0.959 0.924 – 0.996 0.0294 3417 29622 all phecode
735.1 Flat foot Musculoskeletal 0.972 0.892 – 1.06 0.527 620 6092 all phecode
735.2 Acquired toe deformities Musculoskeletal 0.959 0.902 – 1.02 0.176 1323 11983 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.967 0.895 – 1.05 0.4 825 7494 all phecode
735.23 Hallux rigidus Musculoskeletal 0.978 0.878 – 1.09 0.691 405 4005 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.938 0.887 – 0.993 0.0268 1470 14295 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.981 0.941 – 1.02 0.352 2763 26555 all phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.915 0.739 – 1.13 0.414 104 1033 all phecode
736.2 Acquired deformities of finger Musculoskeletal 0.902 0.778 – 1.04 0.169 215 2142 all phecode
736.3 Acquired deformities of hip Musculoskeletal 1.17 0.882 – 1.54 0.28 60 590 all phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.975 0.867 – 1.1 0.676 325 3247 all phecode
736.5 Acquired deformities of knee Musculoskeletal 0.962 0.841 – 1.1 0.575 246 2460 all phecode
736.6 Unequal leg length (acquired) Musculoskeletal 1.02 0.906 – 1.14 0.764 339 3365 all phecode
737 Curvature of spine Musculoskeletal 0.934 0.884 – 0.986 0.0143 1566 15543 all phecode
737.1 Kyphosis (acquired) Musculoskeletal 1 0.905 – 1.1 0.995 479 4748 all phecode
737.2 Lordosis (acquired) Musculoskeletal 1.11 0.867 – 1.43 0.402 70 700 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.913 0.858 – 0.972 0.0042 1203 11982 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1 0.959 – 1.05 0.947 2443 24187 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.09 1.02 – 1.17 0.00981 1057 10542 all phecode
739 Contracture of joint Musculoskeletal 0.928 0.851 – 1.01 0.0957 621 6207 all phecode
740 Osteoarthrosis Musculoskeletal 1.12 1.1 – 1.14 6.95e-26 16169 30268 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.08 1.05 – 1.11 2.83e-07 7005 27422 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.06 1.03 – 1.1 4.71e-05 6176 26155 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.08 0.992 – 1.17 0.0778 713 7116 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.05 0.996 – 1.11 0.0669 1609 12092 all phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 1.18 1.05 – 1.32 0.00542 373 3586 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.13 1.1 – 1.15 2.88e-27 15497 30141 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.01 0.988 – 1.04 0.321 8555 35884 all phecode
741.1 Ankylosis of joint Musculoskeletal 0.897 0.782 – 1.03 0.123 245 2445 all phecode
741.2 Stiffness of joint Musculoskeletal 0.944 0.888 – 1 0.0616 1268 12594 all phecode
741.3 Difficulty in walking Musculoskeletal 1.06 1.02 – 1.11 0.00462 2558 23116 all phecode
741.4 Joint effusions Musculoskeletal 0.989 0.947 – 1.03 0.623 2493 24199 all phecode
741.5 Hemarthrosis Musculoskeletal 1.06 0.855 – 1.32 0.586 94 937 all phecode
741.6 Villonodular synovitis Musculoskeletal 0.909 0.702 – 1.18 0.469 68 666 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.995 0.962 – 1.03 0.747 4404 33771 all phecode
742.1 Loose body in joint Musculoskeletal 1.22 1.03 – 1.45 0.0218 156 1554 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.89 0.785 – 1.01 0.069 280 2792 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.01 0.878 – 1.16 0.914 245 2450 all phecode
742.9 Other derangement of joint Musculoskeletal 0.993 0.96 – 1.03 0.681 4107 32972 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.937 0.913 – 0.96 3.28e-07 9223 36921 all phecode
743.1 Osteoporosis Musculoskeletal 0.915 0.88 – 0.951 6.49e-06 3712 19477 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.913 0.878 – 0.949 4.03e-06 3657 19276 all phecode
743.12 Senile osteoporosis Musculoskeletal 0.847 0.778 – 0.922 0.000123 703 5804 all phecode
743.13 Other specified osteoporosis Musculoskeletal 0.897 0.793 – 1.01 0.0837 321 3141 all phecode
743.2 Pathologic fracture Musculoskeletal 0.946 0.886 – 1.01 0.0962 1112 10563 all phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 0.953 0.862 – 1.05 0.343 475 4629 all phecode
743.22 Pathologic fracture of femur Musculoskeletal 0.967 0.806 – 1.16 0.72 143 1391 all phecode
743.4 Stress fracture Musculoskeletal 0.879 0.789 – 0.98 0.0204 407 4046 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.929 0.903 – 0.955 2.17e-07 6970 35237 all phecode
745 Pain in joint Musculoskeletal 0.986 0.967 – 1.01 0.162 19848 26918 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.979 0.936 – 1.02 0.368 2236 22256 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.01 0.964 – 1.07 0.57 1767 17598 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.956 0.879 – 1.04 0.289 650 6497 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.08 0.994 – 1.16 0.0691 751 7480 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.02 0.921 – 1.14 0.664 410 4090 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.876 0.796 – 0.964 0.00664 501 5010 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.08 0.883 – 1.31 0.468 111 1110 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.897 0.82 – 0.983 0.0193 555 5549 all phecode
749.1 Cleft palate Congenital Anomalies 0.794 0.642 – 0.981 0.0328 97 970 all phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.993 0.808 – 1.22 0.945 105 1041 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.995 0.925 – 1.07 0.891 893 8919 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.934 0.835 – 1.04 0.23 366 3655 all phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 1.02 0.838 – 1.23 0.869 119 1185 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.907 0.732 – 1.12 0.369 99 982 all phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 0.939 0.783 – 1.13 0.496 134 1332 all phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 0.975 0.735 – 1.29 0.862 60 593 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.03 0.932 – 1.13 0.61 531 5300 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.954 0.843 – 1.08 0.454 313 3129 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.13 0.977 – 1.32 0.0987 222 2214 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.993 0.947 – 1.04 0.785 2008 19975 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.958 0.876 – 1.05 0.346 574 5740 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.96 0.861 – 1.07 0.465 384 3840 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.971 0.818 – 1.15 0.732 153 1527 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.01 0.953 – 1.07 0.751 1379 13704 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.981 0.915 – 1.05 0.582 976 9685 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.999 0.882 – 1.13 0.984 294 2927 all phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.03 0.883 – 1.21 0.676 182 1809 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.11 1.04 – 1.19 0.00112 1133 11313 all phecode
752.1 Neural tube defects Congenital Anomalies 1.12 1.04 – 1.2 0.00251 923 9209 all phecode
752.11 Spina bifida Congenital Anomalies 1.06 0.908 – 1.24 0.457 176 1760 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.08 0.94 – 1.24 0.276 232 2320 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.06 0.903 – 1.23 0.499 207 2051 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.943 0.708 – 1.25 0.685 58 580 all phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 1.13 0.845 – 1.5 0.415 56 546 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.07 1.01 – 1.14 0.0293 1216 12116 all phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 0.987 0.821 – 1.19 0.893 135 1333 all phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 1.1 0.999 – 1.2 0.0516 558 5570 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1 0.927 – 1.08 0.959 747 7458 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.957 0.857 – 1.07 0.438 368 3663 all phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 1.07 0.831 – 1.37 0.618 74 740 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1 0.887 – 1.13 0.997 321 3205 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.02 0.871 – 1.19 0.813 185 1847 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.954 0.9 – 1.01 0.113 1358 13579 all phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.944 0.73 – 1.22 0.661 68 680 all phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 1.04 0.808 – 1.33 0.773 71 694 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.916 0.815 – 1.03 0.142 335 3346 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.965 0.902 – 1.03 0.301 1003 10014 all phecode
757 Congenital anomalies of the integument Congenital Anomalies 0.885 0.796 – 0.985 0.0249 401 4001 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.877 0.75 – 1.03 0.0991 185 1845 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.885 0.737 – 1.06 0.188 135 1349 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.944 0.862 – 1.03 0.208 557 5566 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.915 0.712 – 1.18 0.486 71 710 all phecode
760 Back pain Symptoms 1.06 1.04 – 1.08 1.1e-07 16037 30719 all phecode
761 Cervicalgia Symptoms 1 0.975 – 1.03 0.89 6528 39755 all phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 1.03 0.998 – 1.07 0.0641 3657 32599 all phecode
764 Sciatica Symptoms 1.08 1.04 – 1.12 3.88e-05 3542 32015 all phecode
765 Cervical radiculitis Symptoms 0.99 0.94 – 1.04 0.69 1799 17851 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.05 1.02 – 1.08 0.00156 5124 37132 all phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 0.91 0.75 – 1.1 0.34 117 1168 all phecode
769 Nonallopathic lesions NEC Symptoms 0.984 0.923 – 1.05 0.631 1131 11220 all phecode
770 Myalgia and myositis unspecified Symptoms 1.05 1.02 – 1.08 0.000787 5533 34303 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.06 1.02 – 1.09 0.000873 4799 35575 all phecode
771.1 Swelling of limb Symptoms 1.13 1.1 – 1.16 3.92e-16 5743 35539 all phecode
771.2 Cramp of limb Symptoms 1.05 0.985 – 1.12 0.128 1079 10568 all phecode
772 Symptoms of the muscles Symptoms 0.912 0.869 – 0.957 0.000156 2042 20221 all phecode
772.1 Muscular wasting and disuse atrophy Symptoms 0.908 0.817 – 1.01 0.072 422 4199 all phecode
772.2 Spasm of muscle Symptoms 1.01 0.966 – 1.06 0.649 2299 22726 all phecode
772.3 Muscle weakness Symptoms 1.05 1.01 – 1.09 0.0264 2949 28064 all phecode
772.4 Rhabdomyolysis Symptoms 0.972 0.82 – 1.15 0.747 159 1572 all phecode
772.6 Facial weakness Symptoms 0.972 0.88 – 1.07 0.57 478 4742 all phecode
780 Hypothermia/Chills Symptoms 1.02 0.923 – 1.13 0.675 453 4514 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.04 0.996 – 1.08 0.0811 2822 26225 all phecode
781.1 Loss of height Symptoms 0.964 0.794 – 1.17 0.713 130 1269 all phecode
781.2 Abnormal posture Symptoms 0.953 0.724 – 1.25 0.729 57 567 all phecode
782.3 Edema Symptoms 1.16 1.12 – 1.19 3.15e-22 5874 36788 all phecode
782.6 Pallor and flushing Symptoms 0.949 0.884 – 1.02 0.155 927 9252 all phecode
783 Fever of unknown origin Symptoms 1.07 1.04 – 1.1 6.25e-06 5733 40720 all phecode
783.1 Postprocedural fever Symptoms 1.09 0.963 – 1.23 0.174 300 2992 all phecode
785 Abdominal pain Symptoms 1.03 1.01 – 1.05 0.00161 16458 30297 all phecode
788 Syncope and collapse Symptoms 1.01 0.979 – 1.05 0.441 3851 35832 all phecode
789 Nausea and vomiting Symptoms 1.05 1.03 – 1.08 5.44e-06 10568 36098 all phecode
789.1 Persistent vomiting Symptoms 1.17 1.09 – 1.26 3.61e-05 798 7924 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.06 1.01 – 1.11 0.0149 2363 22690 all phecode
790.1 Elevated sedimentation rate Symptoms 1.12 0.973 – 1.29 0.115 236 2322 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.05 1.02 – 1.08 0.000226 7539 37788 all phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.16 1.03 – 1.31 0.0158 309 3075 all phecode
790.9 Abnormal arterial blood gases Symptoms 1.21 1.02 – 1.44 0.0313 155 1521 all phecode
791 Gangrene Symptoms 1.1 0.975 – 1.25 0.121 313 3115 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 0.985 0.945 – 1.03 0.496 2820 14872 all phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 1 0.938 – 1.07 0.975 1100 9861 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.959 0.872 – 1.05 0.384 515 5133 all phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 0.995 0.95 – 1.04 0.833 2182 20242 all phecode
795.8 Abnormal tumor markers Symptoms 0.918 0.872 – 0.966 0.00113 1745 15551 all phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 1.08 0.835 – 1.4 0.55 61 605 all phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 0.954 0.821 – 1.11 0.543 201 2000 all phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.858 0.816 – 0.902 2.08e-09 2125 9930 all phecode
797 Shock Symptoms 1.05 0.967 – 1.15 0.23 605 6050 all phecode
797.1 Cardiogenic shock Symptoms 1.14 0.997 – 1.31 0.0553 242 2420 all phecode
798 Malaise and fatigue Symptoms 1.01 0.992 – 1.04 0.211 11539 35196 all phecode
798.1 Chronic fatigue syndrome Symptoms 1 0.952 – 1.05 0.955 1823 17795 all phecode
800 Fracture of lower limb Injuries & Poisonings 0.988 0.944 – 1.03 0.588 2344 22951 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.979 0.889 – 1.08 0.669 512 4961 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.938 0.862 – 1.02 0.131 670 6582 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.04 0.967 – 1.12 0.297 898 8966 all phecode
800.4 Fracture of patella Injuries & Poisonings 0.993 0.884 – 1.11 0.904 346 3456 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.02 0.979 – 1.07 0.296 2358 22645 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.03 0.965 – 1.1 0.376 1120 11178 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.939 0.841 – 1.05 0.27 380 3765 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.929 0.885 – 0.974 0.00229 2051 20360 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.01 0.929 – 1.09 0.872 734 7322 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.903 0.846 – 0.963 0.00201 1112 11075 all phecode
803.21 Colles' fracture Injuries & Poisonings 0.84 0.738 – 0.955 0.00785 291 2904 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.864 0.787 – 0.95 0.00239 514 5140 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.92 0.872 – 0.97 0.00218 1628 16042 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.998 0.941 – 1.06 0.941 1336 13242 all phecode
807 Fracture of ribs Injuries & Poisonings 0.944 0.87 – 1.02 0.163 683 6815 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.972 0.935 – 1.01 0.169 2941 28633 all phecode
816 Cerebral laceration and contusion Injuries & Poisonings 1.17 0.874 – 1.57 0.289 54 531 all phecode
817 Concussion Injuries & Poisonings 0.986 0.922 – 1.05 0.671 1018 10149 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.893 0.791 – 1.01 0.0671 311 3104 all phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.855 0.686 – 1.07 0.163 90 895 all phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 0.979 0.787 – 1.22 0.849 97 970 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.973 0.931 – 1.02 0.241 2287 22671 all phecode
830 Dislocation Injuries & Poisonings 0.956 0.923 – 0.99 0.0114 3862 34720 all phecode
835 Internal derangement of knee Injuries & Poisonings 0.995 0.95 – 1.04 0.825 2231 21628 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.05 0.95 – 1.15 0.352 496 4954 all phecode
840 Sprains and strains Injuries & Poisonings 0.969 0.944 – 0.994 0.0142 7838 37998 all phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.977 0.891 – 1.07 0.626 537 5356 all phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.989 0.938 – 1.04 0.698 1640 16263 all phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.948 0.91 – 0.987 0.00973 2875 24879 all phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.972 0.921 – 1.03 0.31 1583 15592 all phecode
842 Other sprains and strains Injuries & Poisonings 0.976 0.922 – 1.03 0.413 1407 13924 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.08 1.03 – 1.13 0.00117 2072 20649 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.15 1.11 – 1.2 1.81e-12 2982 27545 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.06 0.955 – 1.17 0.289 460 4600 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.14 1.09 – 1.2 5.66e-08 1985 19675 all phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.03 0.899 – 1.17 0.694 264 2640 all phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.08 0.952 – 1.23 0.228 293 2929 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.11 1.04 – 1.17 0.00083 1310 13087 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.07 1.02 – 1.12 0.00376 2213 21944 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.07 1.02 – 1.12 0.00414 2110 21070 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1.08 0.911 – 1.28 0.383 166 1660 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.05 1.02 – 1.09 0.00209 4117 36734 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.968 0.833 – 1.12 0.667 204 2026 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.938 0.787 – 1.12 0.479 144 1437 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.894 0.843 – 0.949 0.000209 1346 13301 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.979 0.845 – 1.13 0.776 207 2057 all phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 0.941 0.823 – 1.07 0.369 275 2724 all phecode
870.6 Open wound of neck Injuries & Poisonings 0.987 0.853 – 1.14 0.858 214 2128 all phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.23 1.03 – 1.47 0.02 144 1440 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.02 0.987 – 1.06 0.201 3530 32903 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.969 0.885 – 1.06 0.489 572 5701 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.903 0.843 – 0.968 0.00393 984 9772 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.23 1.12 – 1.36 2.28e-05 490 4843 all phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.15 1.01 – 1.3 0.0322 295 2921 all phecode
872 Traumatic amputation Injuries & Poisonings 1.14 1.04 – 1.24 0.00651 551 5477 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.21 1.03 – 1.43 0.0204 170 1697 all phecode
875 Non-healing surgical wound Injuries & Poisonings 1.22 1.12 – 1.34 9.32e-06 572 5720 all phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.22 1.13 – 1.32 2.24e-07 802 8003 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.03 0.961 – 1.1 0.425 1010 10096 all phecode
910 Superficial injury, infected Injuries & Poisonings 0.851 0.702 – 1.03 0.102 119 1161 all phecode
911 Blister Injuries & Poisonings 1.19 1.06 – 1.35 0.0049 302 2996 all phecode
912 Insect bite Injuries & Poisonings 0.99 0.898 – 1.09 0.845 492 4886 all phecode
913 Toxic effect of venom Injuries & Poisonings 0.805 0.715 – 0.906 0.000314 337 3326 all phecode
916 Contusion Injuries & Poisonings 1.04 1 – 1.07 0.0336 4296 38033 all phecode
930 Allergic reaction to food Injuries & Poisonings 1.01 0.933 – 1.09 0.822 763 7596 all phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.912 0.841 – 0.989 0.0264 714 7072 all phecode
938 Dermatitis due to solar radiation Dermatologic 0.897 0.87 – 0.925 3.56e-12 5567 29098 all phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.97 0.837 – 1.12 0.68 217 2164 all phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.889 0.862 – 0.918 2.26e-13 5307 28656 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.978 0.951 – 1.01 0.119 6704 32389 all phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 0.911 0.727 – 1.14 0.415 91 870 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.08 0.922 – 1.26 0.345 188 1880 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.06 0.924 – 1.21 0.426 269 2688 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.943 0.856 – 1.04 0.237 500 4940 all phecode
947 Urticaria Dermatologic 0.978 0.919 – 1.04 0.497 1177 11454 all phecode
949 Allergies, other Injuries & Poisonings 1.01 0.986 – 1.04 0.349 7251 32350 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.1 1 – 1.22 0.0499 494 4940 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.952 0.795 – 1.14 0.593 136 1352 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.05 0.985 – 1.11 0.139 1217 12158 all phecode
958.1 Postoperative shock Injuries & Poisonings 0.985 0.834 – 1.16 0.861 169 1688 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.02 0.836 – 1.25 0.83 114 1140 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.13 1.08 – 1.18 4.25e-08 2479 22087 all phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 1.19 1.06 – 1.34 0.00405 342 3403 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.14 1.08 – 1.2 2.87e-06 1636 16005 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.07 0.974 – 1.17 0.162 528 5234 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.11 1.04 – 1.18 0.0024 1065 10347 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.09 1.01 – 1.18 0.024 803 7976 all phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.12 0.998 – 1.25 0.0549 379 3782 all phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 1.28 0.976 – 1.67 0.0746 62 612 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.09 0.985 – 1.2 0.0954 478 4773 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.04 0.998 – 1.09 0.064 2533 24531 all phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.04 1 – 1.09 0.0487 2469 24057 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.08 0.996 – 1.17 0.0639 743 7337 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.08 0.998 – 1.17 0.0572 712 7027 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.04 0.966 – 1.12 0.299 864 8601 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.18 1.11 – 1.25 1.53e-08 1469 14402 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.01 0.831 – 1.23 0.912 119 1182 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.966 0.781 – 1.19 0.748 103 1006 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.99 0.932 – 1.05 0.759 1254 12464 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.19 1.04 – 1.35 0.0087 281 2797 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.23 0.949 – 1.59 0.119 67 643 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.16 1.02 – 1.32 0.0191 288 2858 all phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 1.24 0.979 – 1.56 0.0745 80 776 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.19 0.969 – 1.45 0.0981 104 1034 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.14 0.933 – 1.39 0.202 113 1130 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.15 0.907 – 1.45 0.253 81 810 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.28 0.995 – 1.64 0.0548 71 703 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.1 1.05 – 1.16 0.00022 1763 16599 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.04 1 – 1.08 0.0282 3448 30885 all phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 1 0.947 – 1.06 0.916 1391 13877 all phecode
985 Toxic effect of other metals Injuries & Poisonings 1.1 0.832 – 1.46 0.493 57 564 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.01 0.835 – 1.22 0.92 129 1275 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.04 1 – 1.07 0.0436 3927 31223 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.12 1.07 – 1.18 8.47e-07 2192 21710 all phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.17 1.04 – 1.33 0.0121 291 2910 all phecode
994.2 Sepsis Injuries & Poisonings 1.11 1.06 – 1.17 6.56e-06 2086 20666 all phecode
994.21 Septic shock Injuries & Poisonings 1.13 1.04 – 1.23 0.00562 627 6260 all phecode
008 Intestinal infection Infectious Diseases 1.05 0.969 – 1.13 0.238 745 6950 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.22 1.08 – 1.37 0.00161 321 2987 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.19 1.04 – 1.37 0.012 251 2331 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.09 0.924 – 1.28 0.31 168 1792 exclusion phecode
010 Tuberculosis Infectious Diseases 1.03 0.791 – 1.33 0.841 61 539 exclusion phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.981 0.668 – 1.44 0.923 27 197 exclusion phecode
038 Septicemia Infectious Diseases 1.23 1.12 – 1.35 1.72e-05 551 5136 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.23 1.01 – 1.51 0.0419 115 1172 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.22 0.887 – 1.67 0.224 50 455 exclusion phecode
038.3 Bacteremia Infectious Diseases 1.23 1.08 – 1.41 0.00226 266 2396 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.1 1.04 – 1.17 0.00122 1319 9006 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.28 1.14 – 1.43 2.12e-05 349 3617 exclusion phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.3 1.11 – 1.52 0.00123 181 1916 exclusion phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.35 1.15 – 1.6 0.000398 157 1700 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.21 1.08 – 1.35 0.000753 381 3462 exclusion phecode
041.21 Rheumatic fever / chorea Infectious Diseases 0.928 0.685 – 1.26 0.628 50 554 exclusion phecode
041.4 E. coli Infectious Diseases 1.19 1.04 – 1.37 0.0136 260 2614 exclusion phecode
041.8 H. pylori Infectious Diseases 0.961 0.726 – 1.27 0.779 58 595 exclusion phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.29 1.02 – 1.62 0.0305 96 849 exclusion phecode
053 Herpes zoster Infectious Diseases 0.932 0.833 – 1.04 0.222 369 3324 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.11 0.821 – 1.51 0.492 50 459 exclusion phecode
054 Herpes simplex Infectious Diseases 1.01 0.906 – 1.12 0.905 422 3794 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.17 0.993 – 1.37 0.0616 193 1614 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.64 0.84 – 3.19 0.148 11 160 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 1.12 0.829 – 1.52 0.454 52 441 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.26 1.04 – 1.52 0.0181 129 966 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.17 0.858 – 1.59 0.323 53 395 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.21 1.05 – 1.39 0.0081 245 2187 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.42 1.07 – 1.9 0.017 59 289 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.41 1.03 – 1.91 0.0301 50 218 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.901 0.838 – 0.969 0.00473 911 7141 exclusion phecode
079 Viral infection Infectious Diseases 0.991 0.939 – 1.05 0.759 1707 8160 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.901 0.84 – 0.967 0.00388 975 7161 exclusion phecode
079.2 Infectious mononucleosis Infectious Diseases 0.875 0.707 – 1.08 0.22 106 885 exclusion phecode
079.9 Viremia, NOS Infectious Diseases 1.25 1.08 – 1.45 0.00315 214 2028 exclusion phecode
080 Postoperative infection Infectious Diseases 1.18 1.07 – 1.29 0.000547 540 5845 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.25 1.12 – 1.4 4.75e-05 389 3473 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.03 0.903 – 1.17 0.683 277 2444 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.999 0.917 – 1.09 0.973 644 6718 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.993 0.907 – 1.09 0.887 555 6022 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.964 0.857 – 1.08 0.533 340 3534 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.05 0.874 – 1.27 0.588 129 1645 exclusion phecode
110.13 Dermatophytosis of the body Infectious Diseases 0.99 0.826 – 1.19 0.917 131 1711 exclusion phecode
110.2 Dermatomycoses Infectious Diseases 1.16 0.931 – 1.43 0.19 103 952 exclusion phecode
112 Candidiasis Infectious Diseases 1.13 1.05 – 1.21 0.00119 876 7564 exclusion phecode
112.3 Candidiasis of skin and nails Infectious Diseases 0.941 0.717 – 1.24 0.664 57 1616 exclusion phecode
117 Mycoses Infectious Diseases 1.09 0.917 – 1.29 0.338 164 1439 exclusion phecode
117.1 Histoplasmosis Infectious Diseases 1.49 0.914 – 2.42 0.11 23 193 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.28 0.949 – 1.73 0.106 49 340 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.852 0.626 – 1.16 0.307 48 434 exclusion phecode
130.1 Lyme disease Infectious Diseases 0.884 0.631 – 1.24 0.474 38 309 exclusion phecode
131 Protozoan infection Infectious Diseases 1.39 0.762 – 2.52 0.285 11 163 exclusion phecode
132 Infestation (lice, mites) Infectious Diseases 1.18 0.877 – 1.59 0.275 46 468 exclusion phecode
134 Helminthiases Infectious Diseases 1.27 0.792 – 2.05 0.318 22 177 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.44 0.766 – 2.7 0.259 16 108 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.11 1.03 – 1.2 0.00509 854 7457 exclusion phecode
145 Cancer of mouth Neoplasms 1.3 1.16 – 1.45 3.58e-06 402 2723 exclusion phecode
145.1 Cancer of lip Neoplasms 1.37 0.828 – 2.28 0.219 16 137 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.39 1.17 – 1.64 0.000128 186 1121 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.922 0.726 – 1.17 0.507 79 717 exclusion phecode
145.4 Cancer of the gums Neoplasms 1.62 1.16 – 2.25 0.00424 54 343 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.53 1.16 – 2.02 0.00287 75 363 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.29 1.15 – 1.45 2.48e-05 355 2312 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.82 1.43 – 2.33 1.64e-06 105 568 exclusion phecode
149.2 Cancer of nasopharynx Neoplasms 1.35 0.91 – 2 0.136 33 211 exclusion phecode
149.3 Cancer of hypopharynx Neoplasms 1.35 0.911 – 2 0.136 28 154 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.3 1.05 – 1.61 0.0146 102 636 exclusion phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 1.4 1.16 – 1.68 0.000382 148 971 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.05 0.792 – 1.4 0.719 60 466 exclusion phecode
150 Cancer of esophagus Neoplasms 1.54 1.25 – 1.91 7.22e-05 99 751 exclusion phecode
151 Cancer of stomach Neoplasms 1.05 0.859 – 1.29 0.61 112 884 exclusion phecode
153 Colorectal cancer Neoplasms 1.04 0.922 – 1.18 0.506 307 2977 exclusion phecode
153.2 Colon cancer Neoplasms 1.09 0.941 – 1.26 0.257 224 2327 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.01 0.86 – 1.18 0.944 194 1749 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.21 0.983 – 1.5 0.0725 109 958 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.15 0.895 – 1.48 0.273 72 634 exclusion phecode
157 Pancreatic cancer Neoplasms 1.1 0.896 – 1.35 0.359 119 943 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1 0.894 – 1.12 0.97 366 3192 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.16 1.04 – 1.29 0.00957 398 3485 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.921 0.669 – 1.27 0.61 44 428 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.18 0.852 – 1.63 0.322 44 300 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.33 1.03 – 1.72 0.0298 74 624 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.92 0.629 – 1.35 0.669 36 255 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.09 0.965 – 1.23 0.169 327 2562 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.03 0.901 – 1.18 0.649 254 2026 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 1.11 1 – 1.24 0.0404 438 3720 exclusion phecode
170.1 Bone cancer Neoplasms 1.2 1.03 – 1.39 0.0185 205 1645 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1.09 0.964 – 1.24 0.163 295 2650 exclusion phecode
172 Skin cancer Neoplasms 0.958 0.908 – 1.01 0.116 2005 7136 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.904 0.846 – 0.966 0.00279 1183 6208 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.889 0.816 – 0.969 0.00745 622 5040 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.953 0.9 – 1.01 0.105 1698 6245 exclusion phecode
172.21 Basal cell carcinoma Neoplasms 0.895 0.83 – 0.965 0.00381 900 4642 exclusion phecode
172.22 Squamous cell carcinoma Neoplasms 1.03 0.938 – 1.13 0.55 583 3196 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.819 0.73 – 0.92 0.000753 363 2293 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.908 0.823 – 1 0.0573 472 3913 exclusion phecode
174 Breast cancer Neoplasms 0.941 0.872 – 1.01 0.112 942 4018 exclusion phecode
174.1 Breast cancer [female] Neoplasms 0.94 0.87 – 1.02 0.114 905 3840 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.943 0.872 – 1.02 0.136 886 3818 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.737 0.562 – 0.966 0.0269 65 592 exclusion phecode
175 Acquired absence of breast Neoplasms 0.923 0.813 – 1.05 0.212 301 2272 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.04 0.936 – 1.15 0.488 442 3333 exclusion phecode
180.1 Cervical cancer Neoplasms 1.09 0.908 – 1.31 0.352 135 1295 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.01 0.9 – 1.13 0.874 356 2584 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.933 0.761 – 1.14 0.5 105 1877 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.01 0.891 – 1.14 0.917 313 2979 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.962 0.806 – 1.15 0.665 151 1504 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.92 0.754 – 1.12 0.414 120 1139 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.09 0.914 – 1.31 0.329 150 1531 exclusion phecode
185 Cancer of prostate Neoplasms 0.842 0.744 – 0.952 0.00626 399 1589 exclusion phecode
187 Cancer of other male genital organs Neoplasms 0.98 0.75 – 1.28 0.881 66 631 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.948 0.546 – 1.65 0.85 14 181 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.898 0.656 – 1.23 0.502 42 389 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.43 0.744 – 2.76 0.282 12 97 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.05 0.951 – 1.16 0.334 474 4570 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.08 0.938 – 1.26 0.273 217 2783 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.1 0.94 – 1.29 0.229 179 2436 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.45 1.02 – 2.06 0.0379 43 421 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.07 0.944 – 1.21 0.291 307 2791 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.11 0.979 – 1.27 0.102 290 2565 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.24 1.02 – 1.52 0.0345 116 1178 exclusion phecode
190 Cancer of eye Neoplasms 0.926 0.655 – 1.31 0.664 44 274 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.01 0.886 – 1.15 0.872 257 2389 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.944 0.809 – 1.1 0.467 189 1564 exclusion phecode
191.11 Cancer of brain Neoplasms 1.01 0.852 – 1.19 0.944 166 1311 exclusion phecode
193 Thyroid cancer Neoplasms 1.07 0.909 – 1.25 0.435 180 2295 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.06 0.873 – 1.3 0.538 115 1361 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.01 0.969 – 1.06 0.538 3803 6337 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.01 0.965 – 1.06 0.653 3739 6336 exclusion phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1.29 1.13 – 1.47 0.000122 276 1686 exclusion phecode
196 Radiotherapy Neoplasms 0.977 0.889 – 1.07 0.629 560 3437 exclusion phecode
197 Chemotherapy Neoplasms 1.11 1.04 – 1.18 0.0028 1227 5333 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.09 1.02 – 1.16 0.00934 1285 5236 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.08 1 – 1.17 0.0505 840 4617 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.21 1.04 – 1.39 0.012 218 1968 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.11 0.956 – 1.29 0.171 220 1681 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.15 0.978 – 1.35 0.0911 193 1429 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.15 0.97 – 1.37 0.106 154 1229 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.32 1.13 – 1.55 0.000527 188 1540 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.07 0.841 – 1.37 0.568 81 608 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.03 0.965 – 1.1 0.363 1222 6068 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.44 0.984 – 2.1 0.0604 30 219 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.16 1.02 – 1.33 0.0288 259 2376 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.18 0.856 – 1.63 0.309 43 384 exclusion phecode
201 Hodgkin's disease Neoplasms 1.32 0.984 – 1.78 0.064 47 409 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.08 0.968 – 1.21 0.167 375 3286 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.09 0.969 – 1.23 0.149 318 2810 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.05 0.896 – 1.23 0.536 183 1510 exclusion phecode
202.22 Reticulosarcoma Neoplasms 0.975 0.685 – 1.39 0.89 36 352 exclusion phecode
202.24 Large cell lymphoma Neoplasms 0.926 0.645 – 1.33 0.675 38 319 exclusion phecode
204 Leukemia Neoplasms 1.06 0.889 – 1.26 0.535 153 1343 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1.07 0.794 – 1.44 0.655 58 448 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.12 0.696 – 1.8 0.639 21 173 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.01 0.701 – 1.46 0.951 38 313 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.14 0.871 – 1.49 0.34 62 505 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.993 0.686 – 1.44 0.97 36 268 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.19 0.697 – 2.04 0.52 16 128 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.1 0.802 – 1.5 0.56 42 438 exclusion phecode
208 Benign neoplasm of colon Neoplasms 0.981 0.933 – 1.03 0.465 2119 8346 exclusion phecode
209 Neuroendocrine tumors Neoplasms 0.964 0.693 – 1.34 0.828 41 515 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.06 0.962 – 1.17 0.235 499 4205 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.06 1 – 1.12 0.0335 1559 8697 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.1 0.991 – 1.22 0.074 437 3952 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.978 0.88 – 1.09 0.688 415 3699 exclusion phecode
214 Lipoma Neoplasms 1.04 0.907 – 1.19 0.59 260 3192 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.975 0.82 – 1.16 0.77 160 2008 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.01 0.939 – 1.08 0.883 1012 9144 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.907 0.867 – 0.949 2.62e-05 2817 8094 exclusion phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 1.26 0.891 – 1.78 0.191 45 416 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.823 0.746 – 0.908 0.000104 502 3752 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.821 0.741 – 0.909 0.000158 464 3438 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.94 0.878 – 1.01 0.0743 1154 4797 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.871 0.786 – 0.965 0.00806 461 4411 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.946 0.878 – 1.02 0.14 944 4715 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.905 0.785 – 1.04 0.173 226 2392 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.973 0.883 – 1.07 0.577 506 4088 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.759 0.647 – 0.891 0.000721 182 1720 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.08 0.96 – 1.22 0.191 326 2723 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.872 0.733 – 1.04 0.121 161 1399 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.895 0.742 – 1.08 0.249 134 1127 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.07 0.941 – 1.22 0.301 275 2764 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1 0.865 – 1.16 0.993 213 2174 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.24 0.963 – 1.58 0.0966 71 639 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.01 0.89 – 1.15 0.837 259 3226 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.975 0.86 – 1.11 0.699 283 3878 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.01 0.777 – 1.31 0.948 63 965 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.949 0.801 – 1.13 0.55 157 1863 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.919 0.71 – 1.19 0.519 63 1012 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.789 0.718 – 0.867 9.16e-07 538 4535 exclusion phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.733 0.651 – 0.824 2.25e-07 355 2832 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.98 0.927 – 1.04 0.463 1669 8554 exclusion phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.97 0.91 – 1.03 0.34 1210 7778 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.02 0.889 – 1.18 0.736 219 2530 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.02 0.933 – 1.11 0.661 605 5567 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.985 0.892 – 1.09 0.764 475 4945 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.06 0.923 – 1.22 0.415 236 3181 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.01 0.897 – 1.15 0.821 299 3335 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.849 0.694 – 1.04 0.11 118 1249 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.1 0.684 – 1.78 0.689 19 307 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.827 0.645 – 1.06 0.135 72 698 exclusion phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.861 0.608 – 1.22 0.398 38 356 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.04 0.98 – 1.1 0.205 1647 7677 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.958 0.855 – 1.07 0.46 351 4262 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.06 0.932 – 1.2 0.382 284 3037 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.04 0.979 – 1.1 0.212 1538 7562 exclusion phecode
245 Thyroiditis Endocrine/metabolic 1.18 1.01 – 1.39 0.0399 178 2110 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.3 1.09 – 1.56 0.00431 138 1770 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.3 1.08 – 1.56 0.00486 137 1751 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.01 0.952 – 1.08 0.651 1301 7120 exclusion phecode
246.2 Thyroid cyst Endocrine/metabolic 0.816 0.529 – 1.26 0.358 25 228 exclusion phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1.02 0.881 – 1.18 0.809 218 2156 exclusion phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.13 0.938 – 1.37 0.197 169 1894 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.11 1.04 – 1.17 0.000713 1798 8752 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.23 1.06 – 1.43 0.00607 469 2920 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.9 1.3 – 2.78 0.000939 103 226 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.28 1 – 1.63 0.0503 154 616 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.45 1.12 – 1.88 0.00463 189 705 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.59 1.24 – 2.05 0.000319 160 588 exclusion phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 1.62 1.07 – 2.45 0.0238 49 173 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.15 1.06 – 1.24 0.000417 1078 7827 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.97 1.3 – 3 0.00147 77 288 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.47 1.22 – 1.77 4.03e-05 173 3130 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.28 1.05 – 1.56 0.0151 207 2284 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.31 1.1 – 1.57 0.00297 215 3893 exclusion phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.3 0.994 – 1.7 0.0555 71 1331 exclusion phecode
250.3 Insulin pump user Endocrine/metabolic 1.3 1.14 – 1.49 0.000147 438 5081 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.08 1.01 – 1.16 0.0239 1238 8248 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.994 0.856 – 1.15 0.936 232 4125 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.1 1.02 – 1.18 0.012 1125 7996 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.72 1.06 – 2.81 0.0284 26 290 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.34 1.1 – 1.62 0.00305 205 3102 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.13 0.976 – 1.31 0.1 256 2093 exclusion phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.02 0.889 – 1.17 0.777 245 1974 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.08 0.937 – 1.25 0.279 310 2348 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.04 0.942 – 1.15 0.44 477 5165 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.03 0.926 – 1.14 0.613 435 4715 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.13 0.911 – 1.41 0.262 98 1179 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1 0.85 – 1.19 0.958 164 1895 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.04 0.767 – 1.42 0.792 48 670 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.874 0.511 – 1.49 0.622 11 203 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.909 0.635 – 1.3 0.603 32 477 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.27 0.767 – 2.11 0.352 15 182 exclusion phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 0.836 0.493 – 1.42 0.505 18 220 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.07 0.724 – 1.59 0.721 30 242 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.05 0.929 – 1.2 0.409 276 3379 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.951 0.722 – 1.25 0.721 56 924 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.827 0.553 – 1.24 0.353 26 495 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.09 0.659 – 1.79 0.748 15 281 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.15 0.952 – 1.4 0.145 131 1432 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.18 0.976 – 1.44 0.0866 123 1361 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.948 0.825 – 1.09 0.448 237 3240 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.784 0.618 – 0.995 0.0454 78 2257 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 0.99 0.824 – 1.19 0.913 127 1530 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.01 0.842 – 1.22 0.884 122 1469 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.53 0.93 – 2.53 0.0936 17 186 exclusion phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.991 0.677 – 1.45 0.963 31 330 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.986 0.851 – 1.14 0.856 201 2439 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.26 1.17 – 1.35 1.81e-10 988 5553 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.46 1.18 – 1.79 0.00036 147 559 exclusion phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.42 1.29 – 1.55 1.65e-13 600 3325 exclusion phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.48 1.27 – 1.74 1.07e-06 214 1201 exclusion phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.43 1.22 – 1.68 1.04e-05 210 1199 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.2 1.05 – 1.37 0.00895 264 1878 exclusion phecode
260.7 Polyphagia Endocrine/metabolic 0.749 0.429 – 1.31 0.309 16 167 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.11 1.04 – 1.17 0.000518 1599 8182 exclusion phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1.57 0.983 – 2.5 0.0588 22 160 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.26 1.07 – 1.48 0.006 175 1833 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.1 1.04 – 1.17 0.00109 1500 8199 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.864 0.523 – 1.42 0.566 14 118 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.12 0.985 – 1.28 0.0822 269 2874 exclusion phecode
263 Other nutritional deficiency Endocrine/metabolic 1.18 1.05 – 1.32 0.00433 368 3637 exclusion phecode
264 Lack of normal physiological development Endocrine/metabolic 1.14 0.912 – 1.43 0.248 103 699 exclusion phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.04 0.767 – 1.42 0.783 51 309 exclusion phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 1.2 0.856 – 1.69 0.287 38 286 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.34 1.18 – 1.52 8.08e-06 286 3036 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.12 0.96 – 1.3 0.151 201 2098 exclusion phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 1.04 0.729 – 1.48 0.829 34 418 exclusion phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.974 0.666 – 1.43 0.894 29 348 exclusion phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 1.12 0.634 – 1.99 0.692 10 223 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.15 0.973 – 1.36 0.0995 164 1518 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.1 0.855 – 1.42 0.457 72 737 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 0.628 0.372 – 1.06 0.0815 19 142 exclusion phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 0.703 0.397 – 1.25 0.227 18 134 exclusion phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.28 0.992 – 1.65 0.0574 76 663 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.985 0.887 – 1.09 0.773 417 6296 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.974 0.875 – 1.08 0.635 394 6130 exclusion phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.28 0.847 – 1.92 0.243 26 230 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.02 0.972 – 1.07 0.411 2862 7532 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.02 0.972 – 1.07 0.41 2851 7518 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1 0.927 – 1.08 0.969 885 5677 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.07 0.88 – 1.3 0.497 112 2933 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.01 0.906 – 1.13 0.843 426 4669 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.987 0.748 – 1.3 0.929 61 737 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.15 1.01 – 1.31 0.0301 266 4357 exclusion phecode
274.1 Gout Endocrine/metabolic 1.2 1.05 – 1.38 0.00952 232 4169 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.24 1.02 – 1.52 0.0351 106 2021 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.875 0.636 – 1.21 0.415 44 379 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.913 0.664 – 1.25 0.573 43 358 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.2 1.12 – 1.29 4.12e-07 945 8233 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.914 0.607 – 1.38 0.668 27 469 exclusion phecode
275.11 Hereditary hemochromatosis Hematopoietic 1.3 0.59 – 2.87 0.513 7 203 exclusion phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 1.04 0.597 – 1.81 0.889 15 153 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.5 1.32 – 1.71 1.46e-09 273 2426 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.15 1.07 – 1.25 0.000357 738 7005 exclusion phecode
275.51 Hypocalcemia Endocrine/metabolic 1.24 1.07 – 1.44 0.00482 218 1971 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.24 1.09 – 1.4 0.000637 320 2783 exclusion phecode
275.6 Hypercalcemia Endocrine/metabolic 1.17 1.03 – 1.32 0.0175 290 3120 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.22 1.16 – 1.29 1.73e-14 2041 8801 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.3 1.22 – 1.38 1.01e-16 1364 7723 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.23 1.01 – 1.5 0.0406 127 1035 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.34 1.22 – 1.46 1.35e-10 637 4587 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.36 1.24 – 1.48 3.3e-11 600 5079 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.34 1.21 – 1.49 1.66e-08 444 4590 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.23 1.11 – 1.36 0.000105 443 4136 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.24 1.11 – 1.39 0.000183 371 3556 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.36 1.12 – 1.66 0.00234 124 982 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.24 1.16 – 1.33 9.61e-11 1141 7954 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.46 1.27 – 1.69 2.36e-07 239 2587 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.05 0.686 – 1.6 0.828 24 289 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.08 0.995 – 1.17 0.0652 701 8379 exclusion phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.36 0.934 – 1.97 0.109 28 771 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.07 0.9 – 1.26 0.461 161 1518 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.931 0.782 – 1.11 0.422 143 2051 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.958 0.786 – 1.17 0.672 109 1709 exclusion phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.72 1.1 – 2.71 0.0184 17 1926 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.27 1.17 – 1.38 6.43e-09 678 10325 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.58 1.35 – 1.84 5.36e-09 177 10321 exclusion phecode
278.11 Morbid obesity Endocrine/metabolic 1.67 1.23 – 2.26 0.000981 40 10260 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 1.01 0.715 – 1.42 0.969 31 1298 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.16 1.03 – 1.31 0.0159 307 7284 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.08 0.997 – 1.16 0.0602 806 6578 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.13 1 – 1.27 0.0489 328 2565 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.04 0.822 – 1.31 0.76 93 720 exclusion phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 0.959 0.824 – 1.12 0.594 198 1809 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 0.997 0.933 – 1.06 0.921 1119 8305 exclusion phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 1.05 0.885 – 1.24 0.589 171 1473 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.14 1.07 – 1.22 9.18e-05 1078 7054 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.15 1.07 – 1.23 7.44e-05 1043 7020 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.19 1.07 – 1.32 0.0017 408 3775 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.29 1.05 – 1.58 0.0159 116 1161 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.22 0.926 – 1.62 0.156 62 579 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.51 0.992 – 2.29 0.0548 28 267 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.15 0.82 – 1.61 0.418 43 434 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.27 0.967 – 1.66 0.0855 63 652 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.14 0.883 – 1.46 0.321 69 693 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.07 0.772 – 1.47 0.7 46 437 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.4 1 – 1.95 0.0479 38 411 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.25 0.872 – 1.79 0.224 33 345 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.979 0.595 – 1.61 0.932 15 152 exclusion phecode
284 Aplastic anemia Hematopoietic 1.32 1.12 – 1.55 0.000697 181 1365 exclusion phecode
284.1 Pancytopenia Hematopoietic 1.32 1.11 – 1.57 0.0017 157 1208 exclusion phecode
285 Other anemias Hematopoietic 1.15 1.1 – 1.21 9.9e-10 2829 7835 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.18 1.09 – 1.28 2.27e-05 806 5912 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.4 1.28 – 1.54 4e-12 523 4091 exclusion phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.48 1.28 – 1.71 1.68e-07 221 1743 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.31 1.11 – 1.54 0.00119 182 1437 exclusion phecode
286 Coagulation defects Hematopoietic 1.09 1 – 1.17 0.0371 767 7586 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.92 0.678 – 1.25 0.594 50 594 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.712 0.445 – 1.14 0.156 20 197 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.09 0.696 – 1.71 0.702 22 307 exclusion phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.05 0.962 – 1.15 0.262 550 5391 exclusion phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 1 0.674 – 1.49 0.995 34 325 exclusion phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 1.07 0.793 – 1.43 0.676 50 500 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.912 0.625 – 1.33 0.632 24 279 exclusion phecode
286.6 Defibrination syndrome Hematopoietic 1.05 0.955 – 1.16 0.311 491 5592 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.05 0.958 – 1.14 0.321 588 6545 exclusion phecode
286.8 Hypercoagulable state Hematopoietic 1.03 0.864 – 1.22 0.771 158 1963 exclusion phecode
286.81 Primary hypercoagulable state Hematopoietic 0.995 0.834 – 1.19 0.953 150 1863 exclusion phecode
286.9 Abnormal coagulation profile Hematopoietic 1.27 1.1 – 1.47 0.000879 224 2405 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.08 0.997 – 1.17 0.0583 740 6201 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.743 0.555 – 0.994 0.0452 55 491 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.09 1.01 – 1.19 0.0355 671 5659 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.03 0.852 – 1.26 0.733 119 1303 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.18 0.98 – 1.43 0.0806 135 1209 exclusion phecode
287.4 Qualitative platelet defects Hematopoietic 1.12 0.729 – 1.72 0.605 23 267 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.15 1.08 – 1.22 1.87e-05 1201 8361 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.15 1.05 – 1.27 0.00337 515 3506 exclusion phecode
288.11 Neutropenia Hematopoietic 1.23 1.1 – 1.39 0.000531 341 2383 exclusion phecode
288.2 Elevated white blood cell count Hematopoietic 1.14 1.07 – 1.22 0.000191 962 7794 exclusion phecode
288.3 Eosinophilia Hematopoietic 0.871 0.636 – 1.19 0.392 46 411 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.06 0.952 – 1.17 0.304 440 3991 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.979 0.848 – 1.13 0.768 232 2168 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.06 0.988 – 1.14 0.103 946 7908 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1.22 0.958 – 1.54 0.108 79 834 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.29 0.91 – 1.82 0.154 40 463 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.4 1.12 – 1.75 0.00344 99 843 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.11 0.979 – 1.25 0.104 326 2192 exclusion phecode
290.1 Dementias Mental Disorders 0.94 0.769 – 1.15 0.55 116 945 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.953 0.636 – 1.43 0.813 32 269 exclusion phecode
290.12 Dementia with cerebral degenerations Mental Disorders 0.676 0.408 – 1.12 0.13 15 151 exclusion phecode
290.13 Senile dementia Mental Disorders 0.917 0.713 – 1.18 0.501 75 604 exclusion phecode
290.16 Vascular dementia Mental Disorders 0.997 0.581 – 1.71 0.992 20 144 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.14 0.975 – 1.34 0.0985 200 1357 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.06 0.916 – 1.23 0.43 208 1877 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.15 1.05 – 1.26 0.00225 540 5706 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.87 0.616 – 1.23 0.427 36 500 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.14 0.948 – 1.37 0.165 135 1160 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.16 1.05 – 1.29 0.0051 404 4403 exclusion phecode
292 Neurological disorders Mental Disorders 1.1 1.04 – 1.17 0.00204 1340 8914 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.12 1.02 – 1.23 0.0182 514 4104 exclusion phecode
292.11 Aphasia Mental Disorders 1.04 0.876 – 1.23 0.659 158 1414 exclusion phecode
292.12 Symbolic dysfunction Mental Disorders 0.903 0.664 – 1.23 0.514 45 448 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.955 0.759 – 1.2 0.693 83 779 exclusion phecode
292.3 Memory loss Mental Disorders 0.918 0.825 – 1.02 0.12 394 3874 exclusion phecode
292.4 Altered mental status Mental Disorders 1.21 1.1 – 1.32 8.65e-05 544 4644 exclusion phecode
292.5 Transient alteration of awareness Mental Disorders 1.03 0.838 – 1.28 0.755 105 944 exclusion phecode
292.6 Hallucinations Mental Disorders 1.3 0.961 – 1.77 0.0878 50 472 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.12 0.905 – 1.38 0.301 109 942 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.08 1.01 – 1.15 0.0285 1033 8730 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.14 0.984 – 1.32 0.0814 211 1890 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.14 0.785 – 1.65 0.493 30 327 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.29 0.847 – 1.97 0.235 24 252 exclusion phecode
295.3 Psychosis Mental Disorders 1.17 0.994 – 1.38 0.0589 175 1527 exclusion phecode
296 Mood disorders Mental Disorders 1.09 1.04 – 1.14 0.000196 3358 5135 exclusion phecode
296.1 Bipolar Mental Disorders 1.17 1.03 – 1.34 0.0153 288 3055 exclusion phecode
296.2 Depression Mental Disorders 1.09 1.04 – 1.14 0.000402 3217 5134 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.1 1.04 – 1.15 0.000209 2978 5134 exclusion phecode
297 Suicidal ideation or attempt Mental Disorders 1.32 1.15 – 1.5 5.07e-05 273 2462 exclusion phecode
297.1 Suicidal ideation Mental Disorders 1.29 1.11 – 1.5 0.000947 211 2001 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.35 1.08 – 1.69 0.00775 99 768 exclusion phecode
300 Anxiety disorders Mental Disorders 1.11 1.06 – 1.16 2.9e-06 3742 5135 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.12 1.07 – 1.17 1.86e-06 3556 5135 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 1.1 1.03 – 1.17 0.00392 1339 4978 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.05 0.928 – 1.19 0.429 330 3115 exclusion phecode
300.13 Phobia Mental Disorders 1.15 1 – 1.33 0.0469 243 2450 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.796 0.619 – 1.02 0.0769 75 881 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.08 0.99 – 1.19 0.0808 590 4164 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.1 0.883 – 1.37 0.391 103 1260 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.1 0.937 – 1.28 0.252 192 2136 exclusion phecode
301 Personality disorders Mental Disorders 1.19 0.967 – 1.46 0.101 110 1340 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.17 0.894 – 1.53 0.256 64 700 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 0.895 0.813 – 0.986 0.0251 544 2894 exclusion phecode
302.1 Decreased libido Mental Disorders 0.819 0.657 – 1.02 0.0759 97 1003 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.91 0.855 – 0.967 0.00251 1620 4752 exclusion phecode
303.1 Dissociative disorder Mental Disorders 1.07 0.734 – 1.55 0.734 32 423 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.901 0.847 – 0.959 0.00111 1550 4697 exclusion phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.802 0.66 – 0.975 0.0266 120 1144 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.964 0.85 – 1.09 0.562 312 3000 exclusion phecode
304 Adjustment reaction Mental Disorders 1.08 1 – 1.16 0.0453 930 4959 exclusion phecode
305.2 Eating disorder Mental Disorders 1.21 1.01 – 1.44 0.0356 145 2340 exclusion phecode
306 Other mental disorder Mental Disorders 1.03 0.931 – 1.14 0.553 464 3668 exclusion phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.04 0.867 – 1.24 0.686 156 1234 exclusion phecode
306.9 Tension headache Mental Disorders 0.954 0.816 – 1.12 0.556 189 2011 exclusion phecode
312 Conduct disorders Mental Disorders 1.26 0.975 – 1.62 0.0782 74 661 exclusion phecode
312.3 Impulse control disorder Mental Disorders 0.945 0.61 – 1.46 0.801 23 218 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 1.1 0.993 – 1.21 0.0699 467 4203 exclusion phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1.12 1 – 1.24 0.0412 423 3835 exclusion phecode
313.2 Tics and stuttering Mental Disorders 1.07 0.683 – 1.69 0.754 23 217 exclusion phecode
313.3 Autism Mental Disorders 0.971 0.563 – 1.68 0.917 12 202 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.01 0.854 – 1.2 0.903 167 1581 exclusion phecode
315.1 Learning disorder Mental Disorders 0.934 0.616 – 1.41 0.745 25 273 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.949 0.724 – 1.24 0.705 62 604 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.33 1.24 – 1.43 1.31e-15 963 7539 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.07 0.894 – 1.27 0.477 153 1360 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.25 1.14 – 1.36 3.73e-07 671 4789 exclusion phecode
317.1 Alcoholism Mental Disorders 1.24 1.13 – 1.36 4.18e-06 561 3801 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.14 0.893 – 1.45 0.294 81 651 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.32 1.25 – 1.39 1.44e-25 2004 8160 exclusion phecode
320 Meningitis Neurological 0.979 0.789 – 1.22 0.847 101 872 exclusion phecode
323 Encephalitis Neurological 1.28 0.937 – 1.76 0.12 45 392 exclusion phecode
323.8 Encephalitis, non-infectious Neurological 1.28 0.9 – 1.82 0.169 39 330 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.03 0.779 – 1.36 0.841 52 626 exclusion phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 1.17 0.553 – 2.45 0.687 10 118 exclusion phecode
327 Sleep disorders Neurological 1.03 0.979 – 1.08 0.265 2171 8803 exclusion phecode
327.1 Hypersomnia Neurological 1.01 0.886 – 1.14 0.923 266 5126 exclusion phecode
327.3 Sleep apnea Neurological 0.986 0.917 – 1.06 0.694 898 8640 exclusion phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1.13 0.9 – 1.42 0.296 81 1103 exclusion phecode
327.32 Obstructive sleep apnea Neurological 0.978 0.899 – 1.06 0.601 639 8241 exclusion phecode
327.4 Insomnia Neurological 1.04 0.979 – 1.11 0.192 1270 8485 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.01 0.894 – 1.15 0.835 286 3274 exclusion phecode
327.5 Parasomnia Neurological 1.01 0.803 – 1.27 0.927 74 1455 exclusion phecode
327.6 Circadian rhythm sleep disorder Neurological 0.834 0.616 – 1.13 0.24 54 740 exclusion phecode
327.7 Sleep related movement disorders Neurological 1.02 0.904 – 1.15 0.746 304 4527 exclusion phecode
327.71 Restless legs syndrome Neurological 1.03 0.907 – 1.18 0.63 263 4037 exclusion phecode
327.72 Sleep related leg cramps Neurological 0.968 0.611 – 1.54 0.892 18 181 exclusion phecode
331 Other cerebral degenerations Neurological 1.16 0.984 – 1.37 0.0769 175 1452 exclusion phecode
331.1 Hydrocephalus Neurological 1.13 0.885 – 1.46 0.319 69 663 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.15 0.929 – 1.42 0.2 105 817 exclusion phecode
332 Parkinson's disease Neurological 1.07 0.859 – 1.32 0.566 99 706 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.02 0.931 – 1.11 0.731 607 5909 exclusion phecode
333.1 Essential tremor Neurological 1.01 0.85 – 1.19 0.947 163 1443 exclusion phecode
333.2 Myoclonus Neurological 1.1 0.791 – 1.52 0.579 39 365 exclusion phecode
333.4 Torsion dystonia Neurological 0.947 0.771 – 1.16 0.603 113 785 exclusion phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 0.968 0.639 – 1.47 0.88 29 168 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.1 0.953 – 1.27 0.191 223 2251 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.25 0.767 – 2.03 0.373 21 164 exclusion phecode
334.2 Anterior horn cell disease Neurological 1.39 0.922 – 2.09 0.116 25 213 exclusion phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 1.44 0.845 – 2.46 0.179 17 119 exclusion phecode
335 Multiple sclerosis Neurological 1.03 0.84 – 1.27 0.752 101 931 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.06 0.91 – 1.23 0.456 203 1628 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.44 1.12 – 1.86 0.00477 73 560 exclusion phecode
338 Pain Neurological 1.1 1.06 – 1.15 1.68e-06 4506 6507 exclusion phecode
338.1 Acute pain Neurological 1.11 1.06 – 1.16 1.93e-06 3556 6458 exclusion phecode
338.2 Chronic pain Neurological 1.13 1.07 – 1.19 6.16e-06 2162 6474 exclusion phecode
339 Other headache syndromes Neurological 1.06 1.01 – 1.12 0.0182 2155 8099 exclusion phecode
340 Migraine Neurological 1.06 1 – 1.12 0.0361 1690 7395 exclusion phecode
340.1 Migrain with aura Neurological 1.11 1.03 – 1.2 0.00512 915 6012 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.04 0.727 – 1.49 0.823 34 302 exclusion phecode
342 Hemiplegia Neurological 1.11 0.91 – 1.37 0.293 110 966 exclusion phecode
343 Infantile cerebral palsy Neurological 1.36 0.911 – 2.04 0.131 25 246 exclusion phecode
344 Other paralytic syndromes Neurological 1.25 1.06 – 1.48 0.00848 171 1436 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.1 1.01 – 1.19 0.0335 654 5981 exclusion phecode
345.1 Epilepsy Neurological 1.06 0.907 – 1.24 0.458 194 1787 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.02 0.77 – 1.35 0.9 57 582 exclusion phecode
345.12 Partial epilepsy Neurological 1.04 0.863 – 1.25 0.69 138 1235 exclusion phecode
345.3 Convulsions Neurological 1.12 1.03 – 1.22 0.0114 620 5634 exclusion phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.997 0.711 – 1.4 0.988 40 423 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.04 0.924 – 1.16 0.536 338 3127 exclusion phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.941 0.627 – 1.41 0.767 28 262 exclusion phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 1.18 0.723 – 1.92 0.51 19 257 exclusion phecode
347 Cataplexy and narcolepsy Neurological 1.07 0.693 – 1.66 0.757 20 250 exclusion phecode
348 Other conditions of brain Neurological 1.13 1.02 – 1.25 0.0201 425 4047 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.08 0.936 – 1.25 0.289 215 2071 exclusion phecode
348.4 Cerebral cysts Neurological 0.779 0.582 – 1.04 0.092 53 566 exclusion phecode
348.7 Coma Neurological 1.32 0.998 – 1.76 0.0519 57 529 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.42 1.21 – 1.66 1.29e-05 195 1750 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.02 0.931 – 1.12 0.658 532 5180 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.17 1.02 – 1.34 0.0285 234 2163 exclusion phecode
350 Abnormal movement Neurological 1.07 1.01 – 1.13 0.0205 1494 9072 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.1 1.02 – 1.19 0.014 750 6804 exclusion phecode
350.2 Abnormality of gait Neurological 1.08 1 – 1.17 0.044 815 6558 exclusion phecode
350.3 Lack of coordination Neurological 0.991 0.875 – 1.12 0.891 293 2332 exclusion phecode
350.5 Abnormal reflex Neurological 1.22 0.882 – 1.69 0.229 43 453 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.998 0.816 – 1.22 0.987 118 1103 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.04 0.979 – 1.11 0.2 1352 8345 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.07 0.962 – 1.2 0.202 379 4003 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.11 0.913 – 1.34 0.305 125 1317 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.02 0.86 – 1.2 0.858 161 1792 exclusion phecode
353 Nerve root and plexus disorders Neurological 1.06 0.981 – 1.14 0.146 843 7874 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.963 0.783 – 1.18 0.72 110 956 exclusion phecode
353.2 Nerve root lesions Neurological 1.12 0.728 – 1.72 0.61 24 257 exclusion phecode
355 Complex regional/central pain syndrome Neurological 0.98 0.817 – 1.18 0.832 131 1290 exclusion phecode
355.1 Chronic pain syndrome Neurological 1.13 0.969 – 1.32 0.119 181 1965 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.09 0.982 – 1.22 0.102 395 4283 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.08 0.99 – 1.18 0.0837 623 6312 exclusion phecode
358 Myoneural disorders Neurological 1.07 0.938 – 1.23 0.302 248 2514 exclusion phecode
358.1 Myasthenia gravis Neurological 0.882 0.593 – 1.31 0.534 26 245 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.941 0.832 – 1.06 0.325 309 2559 exclusion phecode
359.1 Muscular dystrophies Neurological 0.841 0.495 – 1.43 0.521 22 153 exclusion phecode
359.2 Myopathy Neurological 0.942 0.831 – 1.07 0.345 294 2454 exclusion phecode
360 Disorders of the globe Sense Organs 0.98 0.669 – 1.43 0.917 30 266 exclusion phecode
360.2 Progressive myopia Sense Organs 0.812 0.503 – 1.31 0.395 19 128 exclusion phecode
361 Retinal detachments and defects Sense Organs 1.08 0.915 – 1.28 0.353 156 1427 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.01 0.775 – 1.32 0.939 65 551 exclusion phecode
362 Other retinal disorders Sense Organs 1.01 0.933 – 1.1 0.76 747 4729 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.967 0.87 – 1.08 0.537 450 3086 exclusion phecode
362.21 Macular degeneration, dry Sense Organs 1.03 0.812 – 1.3 0.815 89 722 exclusion phecode
362.22 Macular degeneration, wet Sense Organs 0.882 0.582 – 1.34 0.553 34 253 exclusion phecode
362.23 Cystoid macular degeneration of retina Sense Organs 0.976 0.783 – 1.22 0.826 88 800 exclusion phecode
362.26 Macular puckering of retina Sense Organs 0.881 0.746 – 1.04 0.136 173 1667 exclusion phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.978 0.795 – 1.2 0.836 114 930 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.977 0.874 – 1.09 0.682 403 2769 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.18 1 – 1.39 0.0443 174 1727 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1.47 1.18 – 1.83 0.00055 87 771 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.918 0.76 – 1.11 0.37 134 1199 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.927 0.749 – 1.15 0.489 97 793 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.999 0.736 – 1.36 0.996 50 491 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.1 0.822 – 1.46 0.53 62 476 exclusion phecode
362.9 Retinal edema Sense Organs 1.01 0.763 – 1.34 0.941 59 565 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.976 0.794 – 1.2 0.817 114 962 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.97 0.756 – 1.24 0.81 73 644 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1 0.878 – 1.14 0.998 283 2369 exclusion phecode
364.1 Corneal opacity Sense Organs 0.909 0.733 – 1.13 0.383 104 821 exclusion phecode
364.2 Corneal edema Sense Organs 1.05 0.693 – 1.6 0.807 22 244 exclusion phecode
364.4 Corneal degenerations Sense Organs 1.05 0.865 – 1.28 0.604 118 907 exclusion phecode
364.41 Keratoconus Sense Organs 0.644 0.396 – 1.05 0.0748 21 155 exclusion phecode
364.5 Corneal dystrophy Sense Organs 1.04 0.848 – 1.29 0.68 106 998 exclusion phecode
364.51 Fuchs' dystrophy Sense Organs 1.06 0.797 – 1.41 0.684 60 530 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.683 0.406 – 1.15 0.153 17 188 exclusion phecode
365 Glaucoma Sense Organs 0.982 0.895 – 1.08 0.694 573 4343 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 1.07 0.899 – 1.26 0.465 166 1308 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.959 0.761 – 1.21 0.723 93 729 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.892 0.67 – 1.19 0.435 67 484 exclusion phecode
366 Cataract Sense Organs 1 0.944 – 1.07 0.922 1738 5909 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.881 0.661 – 1.17 0.385 56 430 exclusion phecode
366.2 Senile cataract Sense Organs 0.98 0.912 – 1.05 0.582 1076 5140 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.945 0.898 – 0.995 0.0304 2073 8929 exclusion phecode
367.1 Myopia Sense Organs 0.901 0.845 – 0.96 0.0014 1236 8271 exclusion phecode
367.2 Astigmatism Sense Organs 0.912 0.849 – 0.979 0.0111 963 7507 exclusion phecode
367.8 Hypermetropia Sense Organs 0.925 0.834 – 1.03 0.138 439 4193 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.1 0.967 – 1.25 0.145 276 2785 exclusion phecode
368 Visual disturbances Sense Organs 1.02 0.958 – 1.08 0.562 1304 9189 exclusion phecode
368.1 Amblyopia Sense Organs 1.15 0.952 – 1.38 0.15 142 1495 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.02 0.894 – 1.17 0.75 257 2306 exclusion phecode
368.3 Anisometropia Sense Organs 0.878 0.658 – 1.17 0.375 57 494 exclusion phecode
368.4 Visual field defects Sense Organs 0.893 0.771 – 1.03 0.131 202 2398 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.991 0.866 – 1.14 0.9 246 2456 exclusion phecode
368.91 Psychophysical visual disturbances Sense Organs 1.31 0.867 – 1.99 0.198 30 248 exclusion phecode
369 Infection of the eye Sense Organs 0.898 0.83 – 0.971 0.00707 768 6955 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.895 0.736 – 1.09 0.267 126 1209 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.891 0.819 – 0.97 0.00794 653 6187 exclusion phecode
370 Keratitis Sense Organs 0.886 0.79 – 0.994 0.0383 363 3031 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.85 0.649 – 1.11 0.237 73 497 exclusion phecode
370.2 Superficial keratitis Sense Organs 0.899 0.743 – 1.09 0.269 135 1226 exclusion phecode
370.3 Keratoconjunctivitis Sense Organs 0.969 0.819 – 1.15 0.709 170 1469 exclusion phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.828 0.61 – 1.12 0.226 51 429 exclusion phecode
371 Inflammation of the eye Sense Organs 0.923 0.862 – 0.989 0.0224 1061 7190 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.07 0.886 – 1.3 0.468 126 1173 exclusion phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.987 0.848 – 1.15 0.86 208 2101 exclusion phecode
371.21 Allergic conjunctivitis Sense Organs 0.97 0.823 – 1.14 0.722 171 1761 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.906 0.839 – 0.978 0.0119 827 5881 exclusion phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 0.941 0.682 – 1.3 0.714 45 323 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.02 0.899 – 1.17 0.716 270 2280 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.929 0.853 – 1.01 0.0932 666 5197 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.837 0.677 – 1.03 0.0999 104 867 exclusion phecode
374.2 Lagophthalmos Sense Organs 1.12 0.87 – 1.44 0.382 71 518 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 1 0.873 – 1.15 0.97 248 2311 exclusion phecode
374.6 Dermatochalasis Sense Organs 0.965 0.829 – 1.12 0.65 193 2010 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.991 0.919 – 1.07 0.811 897 5809 exclusion phecode
375.1 Dry eyes Sense Organs 1 0.93 – 1.08 0.988 970 5921 exclusion phecode
375.2 Epiphora Sense Organs 0.882 0.713 – 1.09 0.244 109 943 exclusion phecode
376 Disorders of the orbit Sense Organs 0.936 0.737 – 1.19 0.584 85 816 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.07 0.916 – 1.25 0.396 187 2041 exclusion phecode
377.1 Optic atrophy Sense Organs 0.92 0.703 – 1.21 0.548 61 600 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.12 0.921 – 1.36 0.257 118 1325 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.1 0.972 – 1.24 0.132 308 2832 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.1 0.946 – 1.29 0.21 195 1886 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.953 0.689 – 1.32 0.771 44 362 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.08 0.844 – 1.37 0.557 83 745 exclusion phecode
379 Other disorders of eye Sense Organs 0.963 0.9 – 1.03 0.286 1109 6488 exclusion phecode
379.1 Scleritis and episcleritis Sense Organs 0.835 0.601 – 1.16 0.28 45 414 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.97 0.894 – 1.05 0.454 783 4805 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.88 0.607 – 1.27 0.499 38 278 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.01 0.777 – 1.32 0.917 62 614 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.01 0.785 – 1.3 0.933 73 591 exclusion phecode
379.51 Pigmentary iris degeneration Sense Organs 0.741 0.423 – 1.3 0.295 18 138 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.922 0.806 – 1.06 0.241 268 2541 exclusion phecode
380 Disorders of external ear Sense Organs 0.902 0.821 – 0.991 0.0315 533 4433 exclusion phecode
380.1 Otitis externa Sense Organs 0.844 0.745 – 0.956 0.00776 292 3392 exclusion phecode
380.4 Impacted cerumen Sense Organs 0.885 0.811 – 0.966 0.00618 622 5170 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.03 0.958 – 1.1 0.455 984 8885 exclusion phecode
381.1 Otitis media Sense Organs 1.03 0.948 – 1.12 0.498 692 7540 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.04 0.953 – 1.14 0.37 570 6551 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.961 0.869 – 1.06 0.436 456 4389 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 1.11 0.787 – 1.57 0.551 30 367 exclusion phecode
381.9 Otorrhea Sense Organs 1.22 0.961 – 1.54 0.103 82 892 exclusion phecode
382 Otalgia Sense Organs 0.97 0.878 – 1.07 0.54 473 4795 exclusion phecode
383 Otosclerosis Sense Organs 1.1 0.78 – 1.56 0.575 33 289 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 0.968 0.796 – 1.18 0.749 126 1334 exclusion phecode
384.1 Myringitis Sense Organs 0.759 0.435 – 1.33 0.333 13 126 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 0.938 0.754 – 1.17 0.568 100 1050 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.928 0.763 – 1.13 0.454 115 1063 exclusion phecode
385.3 Cholesteatoma Sense Organs 0.957 0.757 – 1.21 0.715 77 704 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.862 0.618 – 1.2 0.38 42 313 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.918 0.822 – 1.02 0.126 389 4144 exclusion phecode
386.1 Meniere's disease Sense Organs 0.913 0.702 – 1.19 0.494 69 699 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.912 0.807 – 1.03 0.142 313 3465 exclusion phecode
386.21 Central origin vertigo Sense Organs 0.896 0.778 – 1.03 0.13 239 2681 exclusion phecode
386.3 Labyrinthitis Sense Organs 0.896 0.792 – 1.01 0.0828 305 3323 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.994 0.938 – 1.05 0.825 1533 8939 exclusion phecode
388 Other disorders of ear Sense Organs 1.08 0.936 – 1.24 0.302 235 2220 exclusion phecode
389 Hearing loss Sense Organs 1.01 0.958 – 1.07 0.684 1750 9108 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.962 0.893 – 1.04 0.312 866 6253 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.01 0.88 – 1.17 0.86 231 2287 exclusion phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.887 0.632 – 1.25 0.488 45 353 exclusion phecode
389.4 Tinnitus Sense Organs 1.03 0.94 – 1.13 0.521 536 4740 exclusion phecode
389.5 Disorders of acoustic nerve Sense Organs 1.23 0.847 – 1.77 0.281 35 268 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.09 0.961 – 1.23 0.186 313 2691 exclusion phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 1.05 0.819 – 1.36 0.685 71 628 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.05 0.845 – 1.29 0.685 103 958 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.06 0.726 – 1.55 0.76 25 304 exclusion phecode
394.4 Acute rheumatic heart disease Circulatory System 0.775 0.446 – 1.35 0.366 11 124 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.04 0.87 – 1.25 0.645 146 1151 exclusion phecode
395 Heart valve disorders Circulatory System 1.09 1.01 – 1.18 0.02 885 6001 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.03 0.935 – 1.13 0.581 538 4304 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.19 1.06 – 1.33 0.00271 378 3214 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 0.972 0.794 – 1.19 0.783 121 1016 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.31 0.877 – 1.94 0.189 29 245 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.15 0.989 – 1.34 0.0697 205 2036 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.07 0.999 – 1.14 0.0547 1089 7743 exclusion phecode
401 Hypertension Circulatory System 1.15 1.1 – 1.21 5.69e-09 3346 7626 exclusion phecode
401.1 Essential hypertension Circulatory System 1.15 1.1 – 1.21 7.56e-09 3302 7627 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.39 1.26 – 1.53 2.19e-11 559 4287 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.17 0.964 – 1.43 0.111 115 1846 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.44 1.29 – 1.6 2.65e-11 433 3799 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.3 1.17 – 1.43 3.37e-07 489 4747 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.19 1.12 – 1.27 5.9e-08 1399 6875 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.06 0.871 – 1.3 0.548 114 1634 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.25 1.14 – 1.37 3.07e-06 581 4475 exclusion phecode
411.3 Angina pectoris Circulatory System 1.19 1.06 – 1.33 0.00308 351 3742 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.19 1.11 – 1.27 1.09e-06 1170 6026 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.29 0.833 – 2.01 0.252 22 310 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.21 1.12 – 1.3 1.16e-06 935 5489 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.22 0.957 – 1.55 0.109 78 862 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.17 1.07 – 1.29 0.000928 537 4888 exclusion phecode
414.2 ASCVD Circulatory System 1.11 0.904 – 1.37 0.317 105 1390 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.16 1.06 – 1.27 0.0013 568 6409 exclusion phecode
415.1 Acute pulmonary heart disease Circulatory System 1.14 1.01 – 1.29 0.0313 307 4016 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.14 1.01 – 1.29 0.0308 306 3996 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.18 1.05 – 1.33 0.00721 325 3624 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.23 1.02 – 1.48 0.0264 141 1459 exclusion phecode
416 Cardiomegaly Circulatory System 1.21 1.05 – 1.4 0.0101 223 2598 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.04 0.994 – 1.09 0.0888 2663 8303 exclusion phecode
418.1 Precordial pain Circulatory System 1.05 0.921 – 1.2 0.459 257 2916 exclusion phecode
420 Carditis Circulatory System 0.992 0.881 – 1.12 0.89 325 3199 exclusion phecode
420.1 Myocarditis Circulatory System 1.18 0.721 – 1.94 0.508 16 212 exclusion phecode
420.2 Pericarditis Circulatory System 0.973 0.826 – 1.15 0.74 176 1693 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.08 0.783 – 1.49 0.64 43 368 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.02 0.636 – 1.62 0.945 21 235 exclusion phecode
420.3 Endocarditis Circulatory System 0.984 0.831 – 1.17 0.853 162 1555 exclusion phecode
425 Cardiomyopathy Circulatory System 1.15 1.03 – 1.29 0.0123 365 3873 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.14 1.02 – 1.28 0.0229 347 3682 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.917 0.616 – 1.37 0.672 30 393 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.36 0.919 – 2.02 0.123 26 421 exclusion phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.13 0.884 – 1.45 0.326 72 673 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.81 1.14 – 2.88 0.012 24 212 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.1 1.05 – 1.16 0.000188 2393 6433 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.11 0.97 – 1.26 0.134 282 2269 exclusion phecode
426.21 First degree AV block Circulatory System 1.04 0.884 – 1.22 0.631 184 1698 exclusion phecode
426.22 Mobitz II AV block Circulatory System 1.42 0.735 – 2.75 0.296 11 121 exclusion phecode
426.23 Second degree AV block Circulatory System 1.15 0.824 – 1.61 0.407 41 380 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1.02 0.802 – 1.29 0.887 85 744 exclusion phecode
426.25 Other heart block Circulatory System 1.33 0.943 – 1.87 0.104 38 337 exclusion phecode
426.3 Bundle branch block Circulatory System 1.05 0.94 – 1.18 0.376 378 2927 exclusion phecode
426.31 Right bundle branch block Circulatory System 0.95 0.825 – 1.09 0.471 235 2178 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.17 0.983 – 1.39 0.0775 152 1610 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.823 0.535 – 1.26 0.374 24 216 exclusion phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.12 1.06 – 1.18 4.98e-05 2072 6305 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.28 1.06 – 1.55 0.0111 137 1431 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.14 1.01 – 1.3 0.0352 305 2302 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.24 1.05 – 1.45 0.00979 189 1569 exclusion phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.2 1.01 – 1.43 0.0384 150 1374 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.05 1 – 1.09 0.0458 3759 6569 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.05 0.958 – 1.16 0.283 517 4083 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.989 0.883 – 1.11 0.843 360 3264 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.16 0.999 – 1.35 0.0513 212 1952 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.03 0.946 – 1.11 0.537 880 4073 exclusion phecode
427.21 Atrial fibrillation Circulatory System 1.01 0.93 – 1.1 0.812 850 3984 exclusion phecode
427.22 Atrial flutter Circulatory System 0.907 0.794 – 1.04 0.149 270 2103 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.09 1.03 – 1.15 0.00322 1873 6497 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.02 0.817 – 1.28 0.836 89 1045 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.05 0.724 – 1.51 0.808 31 405 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.06 0.832 – 1.36 0.624 76 797 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.02 0.956 – 1.08 0.59 1413 6465 exclusion phecode
427.6 Premature beats Circulatory System 0.926 0.835 – 1.03 0.147 451 3494 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 0.97 0.81 – 1.16 0.742 144 1322 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.12 1.05 – 1.2 0.000359 1198 6476 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.02 0.863 – 1.2 0.845 174 1536 exclusion phecode
427.9 Palpitations Circulatory System 0.919 0.857 – 0.984 0.0162 1079 6085 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.21 1.12 – 1.32 7.23e-06 692 5011 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.2 1.1 – 1.32 6.89e-05 592 4695 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.24 1.13 – 1.36 6.01e-06 568 4489 exclusion phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.26 1.12 – 1.43 0.000196 312 2812 exclusion phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.27 1.09 – 1.47 0.00195 207 2667 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.07 1.02 – 1.12 0.00474 2642 8036 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.17 1.02 – 1.34 0.0207 243 2297 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.17 1.1 – 1.25 3.6e-06 1140 6729 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.06 1.01 – 1.11 0.028 2144 7990 exclusion phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.16 0.96 – 1.4 0.123 123 1402 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.02 0.872 – 1.2 0.769 183 1622 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.32 0.998 – 1.75 0.0513 60 542 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.02 0.808 – 1.29 0.875 87 759 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.12 0.875 – 1.44 0.361 73 525 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.12 1.05 – 1.2 0.000727 1116 6795 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.12 1 – 1.24 0.0437 418 3096 exclusion phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 0.969 0.731 – 1.28 0.828 60 505 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 0.732 0.42 – 1.28 0.273 16 154 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.16 1.05 – 1.28 0.00258 482 4311 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.18 1.06 – 1.3 0.00155 467 4173 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.04 0.951 – 1.14 0.371 558 4590 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.05 0.955 – 1.16 0.292 483 4143 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.21 1 – 1.47 0.0499 123 1079 exclusion phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1 0.789 – 1.27 0.987 76 904 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.08 0.901 – 1.3 0.398 139 1421 exclusion phecode
440 Atherosclerosis Circulatory System 1.16 1.05 – 1.28 0.00322 483 3834 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.05 0.777 – 1.41 0.771 53 473 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.05 0.926 – 1.19 0.441 289 2602 exclusion phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.27 0.947 – 1.7 0.111 57 444 exclusion phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 0.996 0.855 – 1.16 0.956 202 1833 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.16 0.969 – 1.38 0.107 146 1519 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.19 0.993 – 1.43 0.059 141 1086 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.11 0.854 – 1.44 0.442 64 493 exclusion phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.2 0.884 – 1.64 0.24 49 341 exclusion phecode
442 Other aneurysm Circulatory System 1.18 1.07 – 1.29 0.000535 538 4204 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.15 1.03 – 1.29 0.0141 359 3044 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.08 0.939 – 1.25 0.271 231 1842 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 0.927 0.625 – 1.38 0.707 26 331 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.25 0.839 – 1.87 0.271 26 317 exclusion phecode
442.4 Arterial dissection Circulatory System 0.918 0.667 – 1.26 0.599 41 360 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.44 1.15 – 1.81 0.0018 97 829 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.06 0.974 – 1.14 0.188 751 5181 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 0.915 0.804 – 1.04 0.183 299 1780 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.61 1.01 – 2.57 0.0465 25 321 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.07 0.98 – 1.17 0.13 633 4524 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.16 1.05 – 1.28 0.00367 470 3653 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.12 0.962 – 1.3 0.145 205 1687 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.08 0.853 – 1.37 0.515 85 563 exclusion phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 0.889 0.613 – 1.29 0.537 33 254 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.969 0.79 – 1.19 0.761 112 996 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.786 0.526 – 1.18 0.241 29 233 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.29 0.755 – 2.22 0.348 17 155 exclusion phecode
446.9 Arteritis NOS Circulatory System 0.971 0.756 – 1.25 0.819 74 611 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.11 1.01 – 1.22 0.0268 541 4593 exclusion phecode
447.1 Stricture of artery Circulatory System 1.11 0.915 – 1.35 0.287 127 1103 exclusion phecode
447.7 Aortic ectasia Circulatory System 1.13 0.923 – 1.38 0.241 110 1448 exclusion phecode
448 Disease of capillaries Circulatory System 0.817 0.724 – 0.922 0.00104 338 2641 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.1 0.996 – 1.22 0.0602 431 4714 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.891 0.75 – 1.06 0.189 154 1664 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.955 0.682 – 1.34 0.788 39 565 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1.07 0.997 – 1.15 0.0605 915 7002 exclusion phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 0.963 0.686 – 1.35 0.83 32 571 exclusion phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1.07 0.977 – 1.16 0.15 596 6075 exclusion phecode
452.8 Postphlebitic syndrome Circulatory System 0.698 0.449 – 1.09 0.112 21 348 exclusion phecode
453 Chronic venous hypertension Circulatory System 0.922 0.674 – 1.26 0.614 47 476 exclusion phecode
454 Varicose veins Circulatory System 1 0.919 – 1.1 0.939 608 5675 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 0.989 0.898 – 1.09 0.815 514 4894 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.94 0.833 – 1.06 0.312 316 3463 exclusion phecode
455 Hemorrhoids Circulatory System 0.936 0.879 – 0.997 0.0396 1282 6964 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.949 0.867 – 1.04 0.26 567 5684 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.04 0.929 – 1.16 0.495 364 3134 exclusion phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 0.975 0.735 – 1.29 0.863 55 598 exclusion phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.03 0.918 – 1.16 0.6 336 2996 exclusion phecode
458 Hypotension Circulatory System 1.2 1.13 – 1.28 3.22e-08 1176 7346 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.21 1.07 – 1.37 0.0022 332 2790 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.21 1.06 – 1.4 0.00631 240 2177 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.22 1.14 – 1.3 2.24e-08 1063 7007 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.13 1.07 – 1.2 2.88e-05 1488 8249 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.17 0.997 – 1.37 0.0551 198 1796 exclusion phecode
459.7 Blood vessel replaced Circulatory System 1.24 1.09 – 1.42 0.00122 270 2697 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.1 1.03 – 1.17 0.00439 1216 7763 exclusion phecode
464 Acute sinusitis Respiratory 0.971 0.908 – 1.04 0.398 1058 7669 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.983 0.936 – 1.03 0.494 2314 8379 exclusion phecode
465.2 Acute pharyngitis Respiratory 0.963 0.906 – 1.02 0.22 1387 7845 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.931 0.752 – 1.15 0.509 99 1091 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.964 0.87 – 1.07 0.475 447 4242 exclusion phecode
471 Nasal polyps Respiratory 0.867 0.72 – 1.04 0.134 128 1347 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.858 0.769 – 0.957 0.00607 386 4089 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.07 0.991 – 1.16 0.0813 765 5620 exclusion phecode
473.1 Chronic laryngitis Respiratory 0.845 0.46 – 1.55 0.588 15 141 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.02 0.852 – 1.21 0.859 152 1442 exclusion phecode
473.4 Voice disturbance Respiratory 1.09 1 – 1.19 0.0505 621 4837 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1.07 0.942 – 1.22 0.299 289 2465 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.01 0.838 – 1.23 0.889 129 1165 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.06 0.916 – 1.22 0.441 220 2021 exclusion phecode
475 Chronic sinusitis Respiratory 1.02 0.946 – 1.09 0.668 987 6534 exclusion phecode
475.9 Postnasal drip Respiratory 0.884 0.756 – 1.03 0.122 196 1995 exclusion phecode
476 Allergic rhinitis Respiratory 0.96 0.917 – 1.01 0.0855 2895 6585 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.22 1.07 – 1.39 0.00317 266 2574 exclusion phecode
478 Throat pain Respiratory 1.19 0.979 – 1.45 0.0807 120 1024 exclusion phecode
479 Other upper respiratory disease Respiratory 1.04 0.982 – 1.11 0.166 1311 6567 exclusion phecode
480 Pneumonia Respiratory 1.11 1.05 – 1.18 0.000616 1287 8722 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.13 1 – 1.28 0.0453 309 2487 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.19 0.994 – 1.42 0.0581 139 1193 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.12 0.817 – 1.53 0.483 50 359 exclusion phecode
480.13 MRSA pneumonia Respiratory 1.57 0.936 – 2.63 0.0878 20 272 exclusion phecode
480.2 Viral pneumonia Respiratory 1.2 0.873 – 1.66 0.258 41 379 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.34 0.978 – 1.84 0.0682 47 332 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.34 0.939 – 1.9 0.107 39 297 exclusion phecode
481 Influenza Respiratory 0.953 0.841 – 1.08 0.448 298 3205 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.993 0.912 – 1.08 0.862 646 7069 exclusion phecode
495 Asthma Respiratory 1.04 0.989 – 1.1 0.121 1770 8173 exclusion phecode
495.1 Chronic obstructive asthma Respiratory 1.17 0.909 – 1.52 0.219 66 857 exclusion phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 0.874 0.428 – 1.78 0.71 8 159 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1 0.889 – 1.13 0.973 321 4419 exclusion phecode
496 Chronic airway obstruction Respiratory 1.29 1.21 – 1.38 5.37e-14 1192 6161 exclusion phecode
496.1 Emphysema Respiratory 1.38 1.26 – 1.51 1.86e-11 559 3825 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.38 1.28 – 1.5 1.19e-16 840 5653 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.43 1.32 – 1.54 5.5e-18 770 5285 exclusion phecode
496.3 Bronchiectasis Respiratory 1.14 0.963 – 1.35 0.127 170 1143 exclusion phecode
497 Bronchitis Respiratory 1.05 0.938 – 1.17 0.396 365 4623 exclusion phecode
498 Acute bronchospasm Respiratory 1.22 0.985 – 1.51 0.0684 97 1271 exclusion phecode
499 Cystic fibrosis Respiratory 1.2 0.901 – 1.6 0.211 57 408 exclusion phecode
500 Lung disease due to external agents Respiratory 1.36 1.12 – 1.66 0.00224 122 1106 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.48 0.911 – 2.4 0.114 23 203 exclusion phecode
500.2 Pneumoconiosis Respiratory 0.966 0.458 – 2.04 0.928 10 121 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.48 1.25 – 1.76 6.45e-06 173 1183 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.03 0.872 – 1.23 0.698 165 1637 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.21 1.02 – 1.43 0.0271 164 1657 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.04 0.857 – 1.27 0.669 126 1197 exclusion phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 0.905 0.689 – 1.19 0.477 66 623 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.05 0.936 – 1.18 0.387 342 3215 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.11 1.02 – 1.2 0.0135 701 5222 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.12 1.03 – 1.22 0.0066 659 5524 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.19 1.08 – 1.32 0.000402 475 4713 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.17 1.08 – 1.26 9.74e-05 808 6265 exclusion phecode
509.1 Respiratory failure Respiratory 1.28 1.15 – 1.42 6.61e-06 427 3812 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.14 0.997 – 1.3 0.0546 269 2349 exclusion phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.14 1.02 – 1.27 0.0241 385 3241 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.24 1.1 – 1.4 0.000574 317 3416 exclusion phecode
510 Other diseases of lung Respiratory 1.07 1.01 – 1.14 0.0325 1194 7846 exclusion phecode
510.2 Lung transplant Respiratory 1.25 0.915 – 1.71 0.16 51 373 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.11 1.06 – 1.15 1.35e-06 3890 7132 exclusion phecode
512.1 Wheezing Respiratory 1.16 1.01 – 1.34 0.0405 215 3292 exclusion phecode
512.2 Painful respiration Respiratory 1.09 0.992 – 1.19 0.0743 552 5258 exclusion phecode
512.3 Abnormal chest sounds Respiratory 1.17 0.904 – 1.52 0.23 73 608 exclusion phecode
512.7 Shortness of breath Respiratory 1.15 1.09 – 1.21 3.02e-07 1926 7104 exclusion phecode
512.8 Cough Respiratory 1.07 1.02 – 1.13 0.00962 2033 7127 exclusion phecode
512.9 Other dyspnea Respiratory 1.1 1.05 – 1.16 0.000302 1997 7106 exclusion phecode
513 Respiratory abnormalities Respiratory 1.12 1.07 – 1.18 1.83e-06 2470 8537 exclusion phecode
513.3 Hypoventilation Respiratory 1.12 0.934 – 1.35 0.22 128 1878 exclusion phecode
513.31 Apnea Respiratory 1.08 0.852 – 1.38 0.517 76 960 exclusion phecode
513.32 Orthopnea Respiratory 1.18 0.815 – 1.71 0.383 28 412 exclusion phecode
513.4 Hyperventilation Respiratory 1.29 1.03 – 1.61 0.029 94 1120 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.14 0.831 – 1.56 0.416 40 488 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.11 1.04 – 1.18 0.00186 1193 7434 exclusion phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 0.77 0.57 – 1.04 0.0873 52 543 exclusion phecode
514.2 Solitary pulmonary nodule Respiratory 1.07 0.988 – 1.17 0.0927 652 5644 exclusion phecode
516 Abnormal sputum Respiratory 1.2 1.02 – 1.42 0.0301 169 1494 exclusion phecode
516.1 Hemoptysis Respiratory 1.17 0.971 – 1.4 0.0998 137 1263 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.1 1.04 – 1.17 0.00128 1418 9074 exclusion phecode
519.1 Tracheostomy complications Respiratory 1.64 1.24 – 2.15 0.000434 64 431 exclusion phecode
519.2 Respiratory complications Respiratory 1.06 0.856 – 1.31 0.593 94 928 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.07 0.958 – 1.19 0.238 382 3472 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.14 1.06 – 1.22 0.000172 1037 7618 exclusion phecode
520 Disorders of tooth development Digestive 0.955 0.79 – 1.15 0.632 120 952 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.11 0.816 – 1.51 0.501 52 380 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.91 0.724 – 1.14 0.418 77 638 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.46 1.27 – 1.67 8.77e-08 250 1935 exclusion phecode
521.1 Dental caries Digestive 1.45 1.26 – 1.67 2.27e-07 234 1781 exclusion phecode
521.2 Dental abrasion, erosion and attrition Digestive 1.1 0.559 – 2.16 0.785 8 116 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.29 1.06 – 1.55 0.00978 111 1178 exclusion phecode
522.5 Periapical abscess Digestive 1.39 1.13 – 1.7 0.00174 95 1040 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.27 1.08 – 1.5 0.0046 163 1547 exclusion phecode
523.1 Gingivitis Digestive 1.15 0.806 – 1.64 0.444 38 340 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.45 1.14 – 1.86 0.00299 71 779 exclusion phecode
523.31 Acute periodontitis Digestive 1.43 1.09 – 1.86 0.00859 56 663 exclusion phecode
523.32 Chronic periodontitis Digestive 1.48 0.991 – 2.21 0.0557 30 246 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.01 0.843 – 1.21 0.919 160 1055 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.01 0.816 – 1.26 0.908 110 683 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.31 1.15 – 1.48 4.23e-05 278 2423 exclusion phecode
525.1 Loss of teeth or edentulism Digestive 1.4 1.13 – 1.73 0.00228 105 894 exclusion phecode
526 Diseases of the jaws Digestive 1.03 0.955 – 1.11 0.434 817 6561 exclusion phecode
526.1 Cysts of the jaws Digestive 0.684 0.517 – 0.905 0.00792 53 512 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.946 0.773 – 1.16 0.593 123 786 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 0.988 0.892 – 1.1 0.825 453 3884 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.978 0.874 – 1.1 0.703 371 3116 exclusion phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 0.987 0.856 – 1.14 0.852 237 2005 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 1.32 1.05 – 1.65 0.0152 104 654 exclusion phecode
526.8 Exostosis of jaw Digestive 1.36 0.803 – 2.3 0.253 21 98 exclusion phecode
526.9 Jaw disease NOS Digestive 1.1 0.927 – 1.3 0.282 173 1118 exclusion phecode
527 Diseases of the salivary glands Digestive 1.07 0.963 – 1.19 0.209 425 3834 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 0.949 0.544 – 1.65 0.852 14 141 exclusion phecode
527.2 Sialoadenitis Digestive 1.11 0.887 – 1.38 0.371 95 913 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.17 1.02 – 1.36 0.0282 226 1880 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.06 0.781 – 1.45 0.698 54 529 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.07 0.989 – 1.16 0.0895 751 5899 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.13 0.963 – 1.32 0.135 200 1559 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.18 0.872 – 1.59 0.285 51 490 exclusion phecode
528.12 Oral aphthae Digestive 0.922 0.711 – 1.2 0.543 69 559 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.68 1.3 – 2.17 8.17e-05 74 528 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.82 0.559 – 1.2 0.308 33 296 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.983 0.622 – 1.55 0.943 23 176 exclusion phecode
528.5 Diseases of lips Digestive 0.993 0.822 – 1.2 0.945 142 1063 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.18 0.816 – 1.7 0.385 34 277 exclusion phecode
528.7 Sialolithiasis Digestive 1.25 0.895 – 1.76 0.189 44 339 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.02 0.863 – 1.21 0.79 156 1409 exclusion phecode
529.1 Glossitis Digestive 1.46 0.98 – 2.19 0.0631 30 268 exclusion phecode
529.6 Glossodynia Digestive 1.03 0.706 – 1.49 0.894 30 321 exclusion phecode
530 Diseases of esophagus Digestive 1.11 1.06 – 1.16 5.62e-06 3202 7330 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.1 1.05 – 1.15 2.57e-05 3046 7330 exclusion phecode
530.11 GERD Digestive 1.1 1.05 – 1.15 5.83e-05 2914 7329 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.27 1.01 – 1.6 0.0401 84 907 exclusion phecode
530.13 Barrett's esophagus Digestive 1.38 1.12 – 1.7 0.0023 106 1472 exclusion phecode
530.14 Reflux esophagitis Digestive 1.09 0.976 – 1.22 0.124 367 4224 exclusion phecode
530.15 Eosinophilic esophagitis Digestive 1.07 0.789 – 1.45 0.66 49 627 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.21 1.01 – 1.46 0.0378 137 1353 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1.21 1.05 – 1.4 0.00958 217 2006 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.2 0.992 – 1.44 0.0607 131 1344 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.04 0.73 – 1.47 0.845 43 257 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.57 1.02 – 2.42 0.0426 22 185 exclusion phecode
530.9 Heartburn Digestive 1.08 0.958 – 1.23 0.199 300 3782 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.2 1.09 – 1.33 0.000368 435 4455 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.22 0.959 – 1.56 0.105 81 733 exclusion phecode
531.2 Gastric ulcer Digestive 1.31 1.14 – 1.5 0.000115 247 2646 exclusion phecode
531.3 Duodenal ulcer Digestive 1.14 0.932 – 1.4 0.198 99 883 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.13 0.955 – 1.33 0.159 180 1724 exclusion phecode
531.5 Gastrojejunal ulcer Digestive 1.05 0.746 – 1.49 0.765 38 323 exclusion phecode
532 Dysphagia Digestive 1.23 1.15 – 1.3 1.3e-10 1388 6859 exclusion phecode
535 Gastritis and duodenitis Digestive 1.05 0.967 – 1.15 0.228 611 6299 exclusion phecode
535.1 Acute gastritis Digestive 1.25 1.09 – 1.43 0.00134 238 2623 exclusion phecode
535.2 Atrophic gastritis Digestive 0.907 0.714 – 1.15 0.425 76 786 exclusion phecode
535.6 Duodenitis Digestive 0.882 0.68 – 1.15 0.347 67 710 exclusion phecode
535.8 Other specified gastritis Digestive 0.991 0.835 – 1.18 0.922 142 1439 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1 0.884 – 1.14 0.98 294 2905 exclusion phecode
536 Disorders of function of stomach Digestive 1.1 1.02 – 1.19 0.0143 771 6521 exclusion phecode
536.3 Gastroparesis Digestive 1.26 1.07 – 1.48 0.00484 184 1584 exclusion phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.28 1.06 – 1.54 0.0103 137 858 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.06 0.971 – 1.17 0.184 544 4961 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.13 1.04 – 1.22 0.00256 746 6762 exclusion phecode
537.1 Lesions of stomach and duodenum Digestive 1.62 1.11 – 2.36 0.0126 34 309 exclusion phecode
539 Bariatric surgery Digestive 2.12 1.66 – 2.72 2.13e-09 73 3739 exclusion phecode
540 Appendiceal conditions Digestive 0.904 0.746 – 1.1 0.304 126 1222 exclusion phecode
540.1 Appendicitis Digestive 0.838 0.681 – 1.03 0.0948 110 1037 exclusion phecode
540.11 Acute appendicitis Digestive 0.814 0.65 – 1.02 0.0723 95 855 exclusion phecode
550 Abdominal hernia Digestive 0.98 0.92 – 1.04 0.537 1207 8816 exclusion phecode
550.1 Inguinal hernia Digestive 0.869 0.784 – 0.964 0.00792 445 3017 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.05 0.951 – 1.16 0.321 446 5737 exclusion phecode
550.3 Femoral hernia Digestive 0.807 0.598 – 1.09 0.162 51 272 exclusion phecode
550.4 Umbilical hernia Digestive 0.915 0.774 – 1.08 0.298 155 2658 exclusion phecode
550.5 Ventral hernia Digestive 1.05 0.937 – 1.18 0.396 340 4744 exclusion phecode
550.6 Incisional hernia Digestive 1.07 0.919 – 1.26 0.366 177 2826 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.09 0.987 – 1.21 0.0861 466 3704 exclusion phecode
555.1 Regional enteritis Digestive 1.19 1.05 – 1.35 0.00608 313 2269 exclusion phecode
555.2 Ulcerative colitis Digestive 1.02 0.893 – 1.17 0.77 273 2180 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 0.938 0.795 – 1.11 0.452 175 1300 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.18 0.986 – 1.4 0.0712 159 1371 exclusion phecode
556.1 Ulceration of intestine Digestive 1.16 0.963 – 1.4 0.116 139 1217 exclusion phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 1.22 0.856 – 1.73 0.273 40 393 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.23 1.1 – 1.37 0.000284 381 4374 exclusion phecode
557.1 Celiac disease Digestive 1.13 0.944 – 1.34 0.186 155 1065 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.13 1.05 – 1.21 0.00156 893 6442 exclusion phecode
559 Ileostomy status Digestive 1.21 1.06 – 1.39 0.00637 248 2053 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.16 1.07 – 1.25 0.000233 792 5625 exclusion phecode
560.1 Paralytic ileus Digestive 1.15 1.03 – 1.29 0.0118 385 3274 exclusion phecode
560.2 Impaction of intestine Digestive 1.19 0.958 – 1.47 0.117 111 930 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.22 0.969 – 1.53 0.0914 90 613 exclusion phecode
560.4 Other intestinal obstruction Digestive 1.2 1.08 – 1.32 0.000497 482 3597 exclusion phecode
561 Symptoms involving digestive system Digestive 1.1 1.02 – 1.2 0.0207 672 5257 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 0.998 0.927 – 1.07 0.947 1035 4936 exclusion phecode
562.1 Diverticulosis Digestive 0.992 0.921 – 1.07 0.823 1026 4925 exclusion phecode
562.2 Diverticulitis Digestive 1.15 1 – 1.32 0.0437 249 3143 exclusion phecode
564 Functional digestive disorders Digestive 1.11 1.06 – 1.16 2.01e-05 2747 6964 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.06 0.986 – 1.14 0.112 904 5634 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.13 1.04 – 1.22 0.00487 685 5931 exclusion phecode
565 Anal and rectal conditions Digestive 0.978 0.906 – 1.05 0.559 818 6940 exclusion phecode
565.1 Anal and rectal polyp Digestive 0.863 0.751 – 0.991 0.0372 236 2505 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.23 1.09 – 1.38 0.00074 336 2915 exclusion phecode
568 Other disorders of peritoneum Digestive 1.12 1.01 – 1.25 0.0386 372 3676 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.19 1.04 – 1.36 0.00956 262 2676 exclusion phecode
569 Other disorders of intestine Digestive 1.09 1.03 – 1.15 0.00198 1700 8326 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.39 1.08 – 1.79 0.0102 81 697 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.24 1.1 – 1.41 0.000405 304 3101 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.16 1.07 – 1.25 0.000375 692 7454 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.13 1.04 – 1.23 0.00473 622 7333 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.21 1.03 – 1.42 0.0183 178 1964 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.41 1.01 – 1.97 0.0464 38 370 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.26 1.08 – 1.46 0.00311 201 1842 exclusion phecode
571.81 Portal hypertension Digestive 1.16 0.938 – 1.42 0.173 106 1127 exclusion phecode
572 Ascites (non malignant) Digestive 1.13 1.04 – 1.24 0.00552 575 5073 exclusion phecode
573 Other disorders of liver Digestive 1.07 0.999 – 1.14 0.0532 1049 7805 exclusion phecode
573.1 Chronic passive congestion of liver Digestive 1.66 1.1 – 2.51 0.0159 33 296 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.17 0.906 – 1.52 0.226 71 550 exclusion phecode
573.3 Hepatomegaly Digestive 1.26 1.01 – 1.57 0.0406 93 1082 exclusion phecode
573.4 Acute and subacute necrosis of liver Digestive 1.24 0.97 – 1.59 0.0861 80 635 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.22 1.06 – 1.4 0.00546 232 1937 exclusion phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.12 1.03 – 1.23 0.0107 560 5842 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.07 0.984 – 1.17 0.11 572 6092 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.13 1.06 – 1.21 0.000504 969 7954 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.1 1 – 1.21 0.0464 520 7209 exclusion phecode
574.1 Cholelithiasis Digestive 1.08 0.977 – 1.19 0.135 455 6806 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.991 0.742 – 1.33 0.954 46 772 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.942 0.743 – 1.19 0.618 77 1290 exclusion phecode
574.2 Calculus of bile duct Digestive 1.07 0.902 – 1.27 0.445 161 1979 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.26 1.05 – 1.52 0.0116 137 1871 exclusion phecode
575 Other biliary tract disease Digestive 1.13 1.03 – 1.25 0.00953 496 5142 exclusion phecode
575.1 Cholangitis Digestive 1.21 0.979 – 1.49 0.0785 101 731 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.29 1.09 – 1.51 0.0026 173 1349 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.758 0.544 – 1.05 0.0999 40 529 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.13 0.957 – 1.33 0.152 170 2192 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.19 1.05 – 1.35 0.0049 302 2508 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.862 0.651 – 1.14 0.299 56 590 exclusion phecode
577 Diseases of pancreas Digestive 1.17 1.07 – 1.28 0.000798 554 4716 exclusion phecode
577.1 Acute pancreatitis Digestive 1.32 1.17 – 1.51 1.71e-05 285 2551 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.59 1.31 – 1.92 2.14e-06 138 982 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.05 0.873 – 1.25 0.63 158 1167 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.05 0.983 – 1.13 0.146 1007 8632 exclusion phecode
578.1 Hematemesis Digestive 1.25 1.03 – 1.52 0.027 117 1060 exclusion phecode
578.2 Blood in stool Digestive 1.07 0.98 – 1.17 0.13 600 5938 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.01 0.912 – 1.11 0.913 476 5034 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.1 0.979 – 1.23 0.109 349 3224 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.08 1.01 – 1.16 0.0233 975 7967 exclusion phecode
579.2 Splenomegaly Digestive 1.19 0.985 – 1.43 0.0712 121 1577 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.07 0.948 – 1.2 0.282 326 3092 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.25 1.11 – 1.41 0.000305 327 3423 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.37 1.08 – 1.73 0.0091 93 846 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.44 0.977 – 2.11 0.0654 30 314 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.74 1.06 – 2.83 0.027 17 241 exclusion phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.37 0.789 – 2.4 0.262 13 135 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.44 1.1 – 1.89 0.00894 71 621 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.22 0.879 – 1.7 0.233 37 466 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.32 1.15 – 1.51 6.97e-05 249 2607 exclusion phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.3 1.09 – 1.56 0.00445 138 1500 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.41 1.18 – 1.68 0.000116 147 1449 exclusion phecode
580.4 Renal sclerosis, NOS Genitourinary 1.26 0.982 – 1.61 0.069 71 754 exclusion phecode
585 Renal failure Genitourinary 1.21 1.14 – 1.29 1.2e-09 1352 7675 exclusion phecode
585.1 Acute renal failure Genitourinary 1.29 1.19 – 1.39 1.57e-10 803 6037 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.23 1.05 – 1.45 0.0115 182 1711 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.21 1.13 – 1.3 1.79e-07 985 6716 exclusion phecode
585.31 Renal dialysis Genitourinary 1.34 1.14 – 1.58 0.000487 176 1530 exclusion phecode
585.32 End stage renal disease Genitourinary 1.44 1.25 – 1.66 5.24e-07 238 2054 exclusion phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.24 1.13 – 1.37 1.54e-05 492 4489 exclusion phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.28 1.1 – 1.5 0.00172 187 1901 exclusion phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.26 1.09 – 1.45 0.00172 232 2389 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.1 1.04 – 1.17 0.00155 1476 8474 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.11 0.882 – 1.4 0.375 86 891 exclusion phecode
586.11 Small kidney Genitourinary 1.15 0.845 – 1.57 0.373 45 515 exclusion phecode
586.12 Vesicoureteral reflux Genitourinary 1.05 0.77 – 1.42 0.772 40 401 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.03 0.904 – 1.18 0.644 257 2645 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.29 0.926 – 1.8 0.132 44 391 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.09 0.974 – 1.21 0.137 391 3829 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.32 1.14 – 1.52 0.000136 231 1742 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.34 1.16 – 1.56 8.63e-05 220 2000 exclusion phecode
588.1 Renal osteodystrophy Genitourinary 1.35 1.06 – 1.72 0.0136 85 582 exclusion phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.3 1.1 – 1.55 0.00268 155 1556 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.18 1.01 – 1.37 0.0358 210 2132 exclusion phecode
590 Pyelonephritis Genitourinary 1.08 0.955 – 1.21 0.226 326 3559 exclusion phecode
591 Urinary tract infection Genitourinary 1.01 0.966 – 1.07 0.559 2300 7506 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.04 0.959 – 1.13 0.344 740 5943 exclusion phecode
592.1 Cystitis Genitourinary 1.05 0.97 – 1.14 0.217 698 5747 exclusion phecode
592.11 Acute cystitis Genitourinary 1.08 0.966 – 1.2 0.183 421 4051 exclusion phecode
592.12 Chronic cystitis Genitourinary 1.24 0.909 – 1.69 0.175 49 587 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.01 0.837 – 1.22 0.923 139 1166 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.95 0.717 – 1.26 0.721 62 490 exclusion phecode
593 Hematuria Genitourinary 1.01 0.945 – 1.09 0.686 970 7381 exclusion phecode
593.1 Gross hematuria Genitourinary 0.976 0.86 – 1.11 0.709 285 2873 exclusion phecode
593.2 Microscopic hematuria Genitourinary 1.02 0.88 – 1.18 0.816 229 2282 exclusion phecode
594 Urinary calculus Genitourinary 1.08 1.02 – 1.15 0.0141 1206 9137 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.08 1.01 – 1.15 0.0283 1117 9085 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.05 0.83 – 1.33 0.687 80 715 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.01 0.884 – 1.16 0.841 234 3001 exclusion phecode
594.8 Renal colic Genitourinary 1.19 0.928 – 1.53 0.168 70 882 exclusion phecode
595 Hydronephrosis Genitourinary 1.18 1.06 – 1.32 0.00347 382 3817 exclusion phecode
596 Other disorders of bladder Genitourinary 1.01 0.929 – 1.1 0.815 673 5962 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.08 0.847 – 1.38 0.529 75 680 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1.03 0.926 – 1.16 0.544 381 3817 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.04 0.917 – 1.19 0.525 278 2509 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.02 0.846 – 1.23 0.84 129 1171 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.04 0.897 – 1.2 0.619 217 2148 exclusion phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.17 0.853 – 1.6 0.333 40 454 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.61 1.04 – 2.5 0.0311 25 281 exclusion phecode
598.4 Other cells and casts in urine Genitourinary 1.44 0.92 – 2.27 0.11 23 247 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.988 0.945 – 1.03 0.601 3011 7568 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.822 0.68 – 0.994 0.0435 132 1245 exclusion phecode
599.2 Retention of urine Genitourinary 1.02 0.952 – 1.09 0.574 1038 6664 exclusion phecode
599.3 Dysuria Genitourinary 0.97 0.906 – 1.04 0.379 1049 6736 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.972 0.905 – 1.05 0.447 972 6365 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 0.966 0.903 – 1.03 0.318 1105 6871 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.21 1.01 – 1.46 0.0386 142 1204 exclusion phecode
599.7 Urethral discharge Genitourinary 0.989 0.605 – 1.62 0.966 18 194 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 0.953 0.891 – 1.02 0.166 1114 6590 exclusion phecode
599.9 Other abnormality of urination Genitourinary 0.935 0.857 – 1.02 0.133 621 5727 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.887 0.802 – 0.982 0.0205 641 1750 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 0.929 0.784 – 1.1 0.393 157 1631 exclusion phecode
601.1 Prostatitis Genitourinary 0.866 0.675 – 1.11 0.26 76 724 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.754 0.49 – 1.16 0.198 31 199 exclusion phecode
601.12 Chronic prostatitis Genitourinary 0.816 0.431 – 1.55 0.533 12 142 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.885 0.683 – 1.14 0.351 61 681 exclusion phecode
601.4 Balanoposthitis Genitourinary 1.52 0.877 – 2.64 0.136 13 226 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.973 0.647 – 1.46 0.895 23 286 exclusion phecode
602 Other disorders of prostate Genitourinary 1.11 0.84 – 1.46 0.47 67 483 exclusion phecode
602.3 Dysplasia of prostate Genitourinary 1.31 0.674 – 2.53 0.429 15 93 exclusion phecode
603 Other disorders of testis Genitourinary 1.11 0.897 – 1.38 0.33 86 836 exclusion phecode
603.1 Hydrocele Genitourinary 1.04 0.784 – 1.39 0.774 47 521 exclusion phecode
603.2 Spermatocele Genitourinary 1.16 0.852 – 1.59 0.341 40 283 exclusion phecode
604 Disorders of penis Genitourinary 1.02 0.852 – 1.22 0.848 133 1209 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.34 0.846 – 2.13 0.21 16 263 exclusion phecode
604.3 Peyronie's disease Genitourinary 1.04 0.767 – 1.41 0.798 48 330 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.858 0.775 – 0.95 0.00335 496 2198 exclusion phecode
608 Other disorders of male genital organs Genitourinary 0.939 0.834 – 1.06 0.302 317 2629 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.947 0.752 – 1.19 0.641 77 860 exclusion phecode
609.1 Infertility, male Genitourinary 0.982 0.756 – 1.27 0.889 56 653 exclusion phecode
609.11 Azoospermia and oligospermia Genitourinary 1.37 0.864 – 2.17 0.18 14 230 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.751 0.493 – 1.15 0.184 24 295 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.904 0.843 – 0.97 0.00514 1103 4593 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.903 0.818 – 0.997 0.0428 506 3675 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 0.774 0.468 – 1.28 0.317 19 147 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.901 0.835 – 0.974 0.00834 879 4543 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.916 0.818 – 1.02 0.125 390 3126 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.904 0.853 – 0.958 0.000689 1789 4939 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.885 0.83 – 0.943 0.000156 1489 4263 exclusion phecode
611.11 Mammographic microcalcification Genitourinary 0.862 0.766 – 0.97 0.0134 364 2535 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.908 0.847 – 0.974 0.007 1089 4931 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.868 0.753 – 1 0.0527 232 2773 exclusion phecode
612.1 Galactorrhea Genitourinary 0.756 0.521 – 1.1 0.14 34 435 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.02 0.847 – 1.22 0.85 135 2033 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 0.482 0.317 – 0.731 0.000602 36 230 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.948 0.886 – 1.01 0.122 1132 5978 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 0.906 0.765 – 1.07 0.254 152 1564 exclusion phecode
613.5 Mastodynia Genitourinary 1.02 0.926 – 1.13 0.663 489 4210 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.875 0.766 – 1 0.0495 269 2329 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 0.888 0.78 – 1.01 0.0723 273 2469 exclusion phecode
613.9 Breast disorder NOS Genitourinary 0.932 0.838 – 1.04 0.189 424 3595 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1 0.938 – 1.08 0.891 1089 5485 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1 0.792 – 1.27 0.989 84 897 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.04 0.862 – 1.25 0.704 140 1356 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.06 0.706 – 1.59 0.782 31 282 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.956 0.712 – 1.29 0.767 61 500 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.959 0.746 – 1.23 0.743 72 687 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1 0.737 – 1.36 0.997 52 476 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.988 0.918 – 1.06 0.748 944 5450 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.14 0.878 – 1.47 0.329 71 767 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.99 0.916 – 1.07 0.805 820 5315 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.03 0.715 – 1.48 0.877 37 368 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.879 0.666 – 1.16 0.361 59 631 exclusion phecode
615 Endometriosis Genitourinary 1.03 0.931 – 1.15 0.539 433 3999 exclusion phecode
618 Genital prolapse Genitourinary 0.957 0.868 – 1.05 0.373 508 4723 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.932 0.829 – 1.05 0.243 345 3445 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.954 0.798 – 1.14 0.607 145 1379 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.957 0.739 – 1.24 0.743 73 757 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.955 0.77 – 1.18 0.674 103 1118 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 0.989 0.933 – 1.05 0.723 1658 5216 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.892 0.793 – 1 0.0581 344 3480 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 1.01 0.852 – 1.2 0.884 154 1622 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.939 0.789 – 1.12 0.481 163 1311 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.996 0.918 – 1.08 0.925 760 5121 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.02 0.907 – 1.16 0.699 326 3206 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1.08 0.891 – 1.31 0.425 118 1063 exclusion phecode
620.1 Dysplasia of cervix Genitourinary 1.02 0.775 – 1.35 0.88 57 513 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.848 0.653 – 1.1 0.216 63 1163 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.908 0.809 – 1.02 0.101 353 3805 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.871 0.762 – 0.996 0.0436 258 2965 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 0.92 0.754 – 1.12 0.416 123 1162 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.04 0.9 – 1.2 0.591 220 2246 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 1.03 0.928 – 1.14 0.58 437 3600 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 1.08 0.814 – 1.43 0.604 55 525 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 1.33 0.861 – 2.04 0.2 28 159 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.922 0.826 – 1.03 0.149 388 3990 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.976 0.92 – 1.04 0.428 1668 4852 exclusion phecode
625.1 Dyspareunia Genitourinary 0.953 0.854 – 1.06 0.384 405 3480 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.953 0.897 – 1.01 0.119 1676 4395 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.942 0.88 – 1.01 0.0894 1227 4097 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 1.01 0.894 – 1.15 0.833 304 2629 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 0.951 0.865 – 1.05 0.295 547 3486 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.945 0.859 – 1.04 0.249 552 3582 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.933 0.818 – 1.06 0.297 278 2647 exclusion phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.832 0.681 – 1.02 0.0726 108 1134 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.976 0.875 – 1.09 0.655 408 3005 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.9 0.721 – 1.12 0.353 99 955 exclusion phecode
626.8 Infertility, female Genitourinary 0.92 0.803 – 1.05 0.228 255 2068 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.917 0.856 – 0.982 0.0129 1243 3886 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 0.875 0.766 – 0.999 0.0481 277 2549 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.919 0.848 – 0.996 0.0394 834 3588 exclusion phecode
627.21 Symptomatic artificial menopause Genitourinary 0.854 0.594 – 1.23 0.393 40 402 exclusion phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.858 0.695 – 1.06 0.156 113 855 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.893 0.786 – 1.01 0.0804 314 2315 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1.04 0.822 – 1.31 0.766 91 963 exclusion phecode
627.5 Premature menopause and other ovarian failure Genitourinary 1.01 0.827 – 1.24 0.914 118 838 exclusion phecode
628 Ovarian cyst Genitourinary 0.932 0.847 – 1.03 0.149 539 3925 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.07 0.93 – 1.23 0.351 244 2293 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.937 0.743 – 1.18 0.584 90 772 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.818 0.572 – 1.17 0.27 30 347 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.866 0.736 – 1.02 0.0816 183 1632 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.864 0.709 – 1.05 0.147 122 1112 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.848 0.672 – 1.07 0.162 88 909 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.933 0.83 – 1.05 0.24 351 2386 exclusion phecode
636.1 Threatened premature labor Pregnancy Complications 1 0.832 – 1.21 0.964 131 1173 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.998 0.789 – 1.26 0.984 92 869 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.887 0.737 – 1.07 0.204 132 1359 exclusion phecode
636.8 Cervical incompetence Pregnancy Complications 1.16 0.742 – 1.81 0.517 22 245 exclusion phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.12 0.726 – 1.74 0.601 20 240 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.835 0.693 – 1.01 0.057 129 1768 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.889 0.683 – 1.16 0.379 66 885 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.01 0.784 – 1.3 0.947 71 800 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.869 0.608 – 1.24 0.441 35 368 exclusion phecode
644 Anemia during pregnancy Pregnancy Complications 0.904 0.696 – 1.18 0.453 69 747 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.937 0.81 – 1.08 0.375 227 2138 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.07 0.831 – 1.38 0.604 75 655 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.877 0.664 – 1.16 0.356 63 712 exclusion phecode
647.3 Major puerperal infection Pregnancy Complications 0.805 0.493 – 1.31 0.386 20 204 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.946 0.841 – 1.06 0.348 367 2532 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.92 0.76 – 1.11 0.391 124 1610 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.01 0.851 – 1.2 0.92 163 1713 exclusion phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.868 0.647 – 1.16 0.344 54 637 exclusion phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 0.794 0.607 – 1.04 0.0932 65 637 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.908 0.823 – 1 0.0567 514 3055 exclusion phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 0.888 0.757 – 1.04 0.145 188 1757 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.932 0.812 – 1.07 0.312 253 2170 exclusion phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 0.809 0.39 – 1.68 0.569 5 144 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.899 0.785 – 1.03 0.125 266 2143 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.08 0.822 – 1.43 0.568 64 707 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.861 0.614 – 1.21 0.387 44 543 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.705 0.533 – 0.933 0.0146 63 580 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.19 1.12 – 1.26 2.36e-08 1331 9223 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.07 0.938 – 1.22 0.313 259 2612 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.24 1.08 – 1.43 0.00317 224 2219 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.25 1.12 – 1.39 4.56e-05 397 4472 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.21 1.09 – 1.35 0.000301 406 4641 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.27 1.13 – 1.43 6.39e-05 330 3685 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.17 1.04 – 1.33 0.0122 285 3560 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.07 0.972 – 1.18 0.162 485 4893 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 0.982 0.808 – 1.19 0.854 114 1391 exclusion phecode
686.2 Impetigo Dermatologic 1.1 0.885 – 1.37 0.389 102 1017 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.07 0.749 – 1.53 0.709 28 403 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 0.842 0.592 – 1.2 0.336 34 380 exclusion phecode
686.5 Pyoderma Dermatologic 1.77 0.873 – 3.6 0.113 8 144 exclusion phecode
687 Symptoms affecting skin Dermatologic 1.01 0.908 – 1.12 0.9 449 3752 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.981 0.928 – 1.04 0.503 1623 8190 exclusion phecode
687.3 Changes in skin texture Dermatologic 1.05 0.832 – 1.34 0.66 85 837 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.02 0.964 – 1.09 0.44 1359 8010 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.908 0.864 – 0.954 0.000136 2241 8716 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.887 0.831 – 0.947 0.000333 1200 6764 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.887 0.831 – 0.947 0.000326 1200 6752 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.952 0.787 – 1.15 0.611 123 1322 exclusion phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 1.4 0.866 – 2.27 0.169 21 163 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.859 0.78 – 0.947 0.00215 500 4084 exclusion phecode
694.1 Vitiligo Dermatologic 1.18 0.813 – 1.7 0.387 37 300 exclusion phecode
694.2 Other dyschromia Dermatologic 0.838 0.757 – 0.929 0.000727 447 3711 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.07 0.663 – 1.71 0.794 24 163 exclusion phecode
695 Erythematous conditions Dermatologic 0.968 0.898 – 1.04 0.391 844 6904 exclusion phecode
695.1 Toxic erythema Dermatologic 0.94 0.523 – 1.69 0.836 15 173 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.26 0.749 – 2.11 0.386 20 172 exclusion phecode
695.3 Rosacea Dermatologic 0.791 0.707 – 0.885 4.28e-05 366 3953 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.12 0.955 – 1.32 0.163 185 1711 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.08 0.826 – 1.41 0.582 67 616 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.11 0.945 – 1.31 0.198 177 1613 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 1.13 0.928 – 1.38 0.223 113 1324 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1.02 0.834 – 1.25 0.851 105 1866 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.864 0.507 – 1.47 0.59 15 165 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.06 0.881 – 1.27 0.549 132 1504 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.921 0.81 – 1.05 0.207 275 3123 exclusion phecode
696.3 Pityriasis Dermatologic 0.702 0.489 – 1.01 0.055 36 277 exclusion phecode
696.4 Psoriasis Dermatologic 0.98 0.854 – 1.12 0.774 238 2876 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.976 0.847 – 1.12 0.736 222 2603 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.741 0.529 – 1.04 0.0802 41 615 exclusion phecode
697 Sarcoidosis Dermatologic 1.09 0.806 – 1.47 0.583 47 653 exclusion phecode
698 Pruritus and related conditions Dermatologic 0.953 0.869 – 1.04 0.3 557 5421 exclusion phecode
700 Corns and callosities Dermatologic 1.01 0.879 – 1.17 0.85 229 2355 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.943 0.893 – 0.996 0.0355 1735 9024 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.955 0.794 – 1.15 0.625 141 1181 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.973 0.892 – 1.06 0.534 623 5144 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.957 0.792 – 1.16 0.648 133 1404 exclusion phecode
701.4 Keloid scar Dermatologic 0.916 0.77 – 1.09 0.325 158 1531 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1.05 0.843 – 1.32 0.642 91 904 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.86 0.81 – 0.913 8.4e-07 1588 6196 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.819 0.76 – 0.882 1.19e-07 950 5238 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.869 0.815 – 0.927 1.9e-05 1277 6486 exclusion phecode
702.4 Degenerative skin disorders Dermatologic 1.34 0.843 – 2.12 0.217 25 197 exclusion phecode
703 Diseases of nail, NOS Dermatologic 0.94 0.835 – 1.06 0.311 333 3307 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.919 0.78 – 1.08 0.318 167 1978 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.978 0.905 – 1.06 0.568 765 7325 exclusion phecode
704.1 Alopecia Dermatologic 0.888 0.798 – 0.987 0.0282 409 3630 exclusion phecode
704.11 Alopecia Areata Dermatologic 1.42 0.864 – 2.33 0.167 21 179 exclusion phecode
704.12 Telogen effluvium Dermatologic 0.729 0.438 – 1.21 0.223 22 160 exclusion phecode
704.2 Hirsutism Dermatologic 1.13 0.826 – 1.54 0.449 45 882 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.08 0.97 – 1.21 0.155 375 3901 exclusion phecode
705 Disorders of sweat glands Dermatologic 1.03 0.851 – 1.25 0.76 115 1541 exclusion phecode
705.1 Dyshidrosis Dermatologic 0.774 0.52 – 1.15 0.207 33 340 exclusion phecode
705.3 Hidradenitis Dermatologic 1.18 0.842 – 1.64 0.342 33 639 exclusion phecode
705.8 Hyperhidrosis Dermatologic 0.976 0.857 – 1.11 0.713 263 2649 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 0.895 0.846 – 0.948 0.000145 1531 9248 exclusion phecode
706.1 Acne Dermatologic 0.861 0.798 – 0.929 0.000109 832 5978 exclusion phecode
706.2 Sebaceous cyst Dermatologic 0.907 0.833 – 0.987 0.0241 644 6019 exclusion phecode
706.3 Seborrhea Dermatologic 0.528 0.306 – 0.912 0.0219 16 137 exclusion phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.931 0.824 – 1.05 0.247 322 3244 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.2 1.1 – 1.31 4.79e-05 597 5738 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.29 1.11 – 1.5 0.000991 206 1652 exclusion phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.25 1.06 – 1.46 0.00635 180 1928 exclusion phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1.17 1.05 – 1.32 0.00583 356 3547 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.976 0.875 – 1.09 0.668 383 3529 exclusion phecode
709.2 Sicca syndrome Dermatologic 1 0.835 – 1.2 0.982 132 1192 exclusion phecode
709.3 Systemic sclerosis Dermatologic 0.897 0.696 – 1.16 0.402 72 515 exclusion phecode
709.5 Dermatomyositis Dermatologic 0.808 0.507 – 1.29 0.372 18 210 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.23 0.801 – 1.89 0.344 27 213 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.986 0.857 – 1.14 0.848 239 2277 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.27 1.12 – 1.45 0.000202 282 2616 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.28 1.12 – 1.45 0.000217 275 2462 exclusion phecode
710.11 Acute osteomyelitis Musculoskeletal 1.4 1.15 – 1.69 0.000705 130 1196 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.24 1.02 – 1.51 0.0324 126 1049 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.3 1.14 – 1.49 0.000103 258 2362 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 0.808 0.631 – 1.04 0.0916 77 883 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.05 0.766 – 1.44 0.761 46 610 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 0.967 0.679 – 1.38 0.855 31 400 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.08 0.824 – 1.4 0.591 62 642 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.75 1.07 – 2.87 0.026 20 304 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.1 0.995 – 1.22 0.0639 468 4438 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.16 1.04 – 1.3 0.00902 386 3663 exclusion phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.02 0.705 – 1.48 0.916 33 237 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.07 0.935 – 1.23 0.317 244 2802 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.09 0.825 – 1.45 0.537 57 676 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.13 0.842 – 1.51 0.423 50 545 exclusion phecode
716 Other arthropathies Musculoskeletal 1.05 0.997 – 1.1 0.0677 2506 7939 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.9 0.625 – 1.3 0.57 33 432 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.691 0.441 – 1.08 0.108 20 272 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.05 0.998 – 1.1 0.062 2492 7936 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.951 0.711 – 1.27 0.735 52 562 exclusion phecode
720 Spinal stenosis Musculoskeletal 1.08 0.994 – 1.18 0.0692 649 6151 exclusion phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1.14 1.02 – 1.26 0.0155 428 4881 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1.08 1.01 – 1.16 0.0241 1075 7226 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.09 1.01 – 1.16 0.0197 1008 7068 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.14 0.959 – 1.35 0.137 152 1737 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 1.03 0.74 – 1.44 0.851 40 562 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.11 1.04 – 1.18 0.00175 1199 8037 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.11 1.02 – 1.21 0.0149 659 7186 exclusion phecode
722.3 Schmorl's nodes Musculoskeletal 0.887 0.612 – 1.29 0.526 32 264 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.1 1.02 – 1.19 0.0193 752 6798 exclusion phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.26 1 – 1.59 0.0493 92 1084 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.22 0.944 – 1.57 0.129 73 827 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.981 0.877 – 1.1 0.736 370 4256 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 0.993 0.861 – 1.14 0.921 230 2233 exclusion phecode
723.1 Torticollis Musculoskeletal 0.952 0.724 – 1.25 0.727 62 589 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.01 0.94 – 1.09 0.766 890 7601 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 0.996 0.906 – 1.1 0.941 520 5376 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.907 0.729 – 1.13 0.386 98 1021 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.1 0.937 – 1.29 0.244 175 2182 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.07 0.943 – 1.21 0.293 288 3198 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.958 0.91 – 1.01 0.103 2111 7342 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.959 0.905 – 1.02 0.149 1605 7313 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.924 0.788 – 1.09 0.337 173 2098 exclusion phecode
726.3 Bursitis Musculoskeletal 0.874 0.779 – 0.98 0.0212 359 3818 exclusion phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.918 0.798 – 1.06 0.231 228 2653 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.978 0.923 – 1.04 0.442 1618 7309 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.986 0.906 – 1.07 0.739 681 6062 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.949 0.744 – 1.21 0.677 80 907 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.974 0.866 – 1.1 0.659 347 3217 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.963 0.769 – 1.2 0.738 89 1092 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.908 0.819 – 1.01 0.0704 420 4585 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.09 0.927 – 1.29 0.289 167 1482 exclusion phecode
727.8 Plica syndrome Musculoskeletal 0.955 0.704 – 1.3 0.769 50 385 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.982 0.915 – 1.05 0.604 988 7020 exclusion phecode
728.1 Muscular calcification and ossification Musculoskeletal 1.24 0.785 – 1.96 0.355 22 186 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.01 0.801 – 1.28 0.909 77 712 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.872 0.791 – 0.962 0.00625 473 5331 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.708 0.571 – 0.878 0.00169 108 781 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.12 1.03 – 1.22 0.00641 669 6222 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.24 0.762 – 2.03 0.383 19 168 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.947 0.523 – 1.72 0.858 9 304 exclusion phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 0.918 0.579 – 1.46 0.716 21 155 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.21 0.838 – 1.74 0.311 36 353 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.981 0.783 – 1.23 0.865 91 1000 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.03 0.728 – 1.45 0.87 40 530 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.05 0.668 – 1.64 0.84 24 265 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.949 0.889 – 1.01 0.121 1259 6039 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.18 0.875 – 1.58 0.282 53 452 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.21 1.02 – 1.44 0.0304 160 1061 exclusion phecode
733.6 Costochondritis Musculoskeletal 1.11 0.879 – 1.41 0.376 79 878 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.31 1.13 – 1.52 0.000417 207 1900 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.08 0.731 – 1.6 0.694 33 261 exclusion phecode
735 Acquired foot deformities Musculoskeletal 0.937 0.866 – 1.01 0.106 762 6663 exclusion phecode
735.1 Flat foot Musculoskeletal 0.843 0.69 – 1.03 0.0961 109 1399 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 0.947 0.83 – 1.08 0.414 279 2535 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.01 0.848 – 1.2 0.923 160 1562 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 1.01 0.81 – 1.25 0.943 103 848 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.861 0.767 – 0.967 0.0118 348 3312 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 0.929 0.851 – 1.01 0.0966 614 6048 exclusion phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.914 0.612 – 1.36 0.659 32 220 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.05 0.8 – 1.39 0.712 66 463 exclusion phecode
736.3 Acquired deformities of hip Musculoskeletal 0.981 0.585 – 1.64 0.942 16 188 exclusion phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 1.2 0.893 – 1.61 0.229 48 682 exclusion phecode
736.5 Acquired deformities of knee Musculoskeletal 0.985 0.691 – 1.4 0.933 32 499 exclusion phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.904 0.709 – 1.15 0.417 78 779 exclusion phecode
737 Curvature of spine Musculoskeletal 1.03 0.926 – 1.14 0.632 462 3890 exclusion phecode
737.1 Kyphosis (acquired) Musculoskeletal 1.16 0.945 – 1.43 0.154 110 1080 exclusion phecode
737.2 Lordosis (acquired) Musculoskeletal 1.69 0.942 – 3.02 0.0785 12 152 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1 0.897 – 1.12 0.974 386 3060 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.12 1.03 – 1.22 0.00924 631 5535 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.18 1.01 – 1.37 0.0345 198 2157 exclusion phecode
739 Contracture of joint Musculoskeletal 0.986 0.828 – 1.17 0.874 160 1370 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.03 0.986 – 1.08 0.171 2937 7929 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.97 0.907 – 1.04 0.378 1157 6673 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.96 0.894 – 1.03 0.268 1023 6187 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.03 0.853 – 1.24 0.762 122 1668 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.05 0.925 – 1.19 0.451 306 2887 exclusion phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 1.22 0.952 – 1.57 0.116 71 857 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.04 0.987 – 1.09 0.151 2783 7867 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.02 0.966 – 1.07 0.513 1879 8544 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.891 0.671 – 1.18 0.427 54 599 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 0.976 0.866 – 1.1 0.685 323 2891 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 1.13 1.03 – 1.24 0.0132 496 4936 exclusion phecode
741.4 Joint effusions Musculoskeletal 0.978 0.892 – 1.07 0.635 540 5845 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.16 0.715 – 1.88 0.551 18 199 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 1.1 0.609 – 2 0.744 11 169 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.991 0.926 – 1.06 0.8 1043 8142 exclusion phecode
742.1 Loose body in joint Musculoskeletal 1.07 0.744 – 1.54 0.713 28 422 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.949 0.76 – 1.19 0.647 85 933 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.13 0.863 – 1.47 0.38 62 634 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.985 0.919 – 1.06 0.672 985 8034 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.01 0.966 – 1.07 0.56 2537 8248 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.03 0.961 – 1.11 0.38 1230 3995 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.03 0.957 – 1.1 0.445 1217 3952 exclusion phecode
743.12 Senile osteoporosis Musculoskeletal 0.958 0.833 – 1.1 0.541 292 1134 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1.04 0.831 – 1.3 0.729 109 601 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.04 0.923 – 1.18 0.497 326 2028 exclusion phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 1 0.831 – 1.21 0.972 131 862 exclusion phecode
743.22 Pathologic fracture of femur Musculoskeletal 1.41 0.994 – 2 0.0538 43 267 exclusion phecode
743.4 Stress fracture Musculoskeletal 0.822 0.67 – 1.01 0.0609 120 924 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.01 0.954 – 1.07 0.752 1853 7744 exclusion phecode
745 Pain in joint Musculoskeletal 0.96 0.923 – 0.999 0.0443 4517 6498 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.965 0.879 – 1.06 0.455 525 4965 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.02 0.914 – 1.13 0.747 389 3920 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1.02 0.869 – 1.2 0.781 170 1512 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.18 0.982 – 1.43 0.0776 128 1550 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.896 0.721 – 1.11 0.323 88 884 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.875 0.732 – 1.05 0.141 140 1163 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.996 0.67 – 1.48 0.985 29 272 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.966 0.829 – 1.13 0.662 206 1544 exclusion phecode
749.1 Cleft palate Congenital Anomalies 0.871 0.632 – 1.2 0.401 43 310 exclusion phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.973 0.706 – 1.34 0.868 46 303 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 1.14 0.995 – 1.3 0.06 261 2050 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.995 0.794 – 1.25 0.964 88 858 exclusion phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.826 0.552 – 1.24 0.354 29 248 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.07 0.705 – 1.61 0.764 24 258 exclusion phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 0.998 0.72 – 1.38 0.992 39 269 exclusion phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 0.955 0.48 – 1.9 0.896 11 122 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.16 0.981 – 1.36 0.0845 176 1251 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.17 0.951 – 1.45 0.135 110 720 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.15 0.872 – 1.52 0.323 69 509 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.02 0.926 – 1.12 0.7 518 4659 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.975 0.824 – 1.15 0.772 161 1548 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.06 0.868 – 1.3 0.554 116 1100 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.811 0.585 – 1.12 0.209 38 353 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1 0.889 – 1.12 0.996 332 3026 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 1.02 0.887 – 1.17 0.776 227 2060 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.912 0.709 – 1.17 0.471 74 675 exclusion phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.37 1.04 – 1.81 0.027 62 532 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.1 0.954 – 1.27 0.191 227 2647 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.13 0.961 – 1.32 0.142 177 2072 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.871 0.643 – 1.18 0.376 42 500 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.01 0.768 – 1.34 0.927 58 599 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.07 0.779 – 1.46 0.691 52 476 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.746 0.413 – 1.34 0.329 14 150 exclusion phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 1 0.573 – 1.76 0.99 14 144 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.08 0.939 – 1.23 0.293 247 2582 exclusion phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 0.841 0.568 – 1.25 0.389 27 305 exclusion phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 1.11 0.903 – 1.36 0.323 109 1222 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.04 0.887 – 1.22 0.631 175 1999 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.92 0.728 – 1.16 0.484 78 912 exclusion phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 1.14 0.699 – 1.87 0.592 18 180 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.09 0.86 – 1.39 0.47 84 961 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.05 0.774 – 1.43 0.745 50 565 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.04 0.93 – 1.17 0.478 354 3352 exclusion phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.579 0.35 – 0.959 0.0338 21 172 exclusion phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 1.17 0.836 – 1.63 0.364 49 237 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.993 0.765 – 1.29 0.959 62 840 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.06 0.918 – 1.21 0.449 229 2290 exclusion phecode
757 Congenital anomalies of the integument Congenital Anomalies 0.85 0.684 – 1.06 0.142 103 926 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.11 0.839 – 1.46 0.473 58 491 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.07 0.763 – 1.51 0.689 38 363 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.971 0.821 – 1.15 0.734 160 1493 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.934 0.559 – 1.56 0.795 14 188 exclusion phecode
760 Back pain Symptoms 1.09 1.04 – 1.13 0.000138 3440 7569 exclusion phecode
761 Cervicalgia Symptoms 1.06 0.997 – 1.12 0.0617 1576 9228 exclusion phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 1.04 0.956 – 1.13 0.365 662 7263 exclusion phecode
764 Sciatica Symptoms 1.1 1.01 – 1.2 0.0276 611 7266 exclusion phecode
765 Cervical radiculitis Symptoms 1.05 0.938 – 1.17 0.413 371 3862 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.07 1 – 1.15 0.0501 1017 8661 exclusion phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.08 0.705 – 1.65 0.729 28 264 exclusion phecode
769 Nonallopathic lesions NEC Symptoms 1.09 0.959 – 1.24 0.183 292 2634 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.03 0.965 – 1.09 0.408 1254 8242 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.1 1.02 – 1.17 0.00854 1015 8355 exclusion phecode
771.1 Swelling of limb Symptoms 1.13 1.06 – 1.21 0.00032 1061 8316 exclusion phecode
771.2 Cramp of limb Symptoms 1.06 0.921 – 1.22 0.414 233 2375 exclusion phecode
772 Symptoms of the muscles Symptoms 0.934 0.849 – 1.03 0.16 507 4726 exclusion phecode
772.1 Muscular wasting and disuse atrophy Symptoms 1.06 0.872 – 1.28 0.569 123 1091 exclusion phecode
772.2 Spasm of muscle Symptoms 0.977 0.891 – 1.07 0.615 542 5508 exclusion phecode
772.3 Muscle weakness Symptoms 1.04 0.955 – 1.13 0.368 640 6137 exclusion phecode
772.4 Rhabdomyolysis Symptoms 1.08 0.757 – 1.54 0.677 38 338 exclusion phecode
772.6 Facial weakness Symptoms 0.894 0.717 – 1.11 0.318 96 1027 exclusion phecode
780 Hypothermia/Chills Symptoms 1.17 0.946 – 1.44 0.15 104 987 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.02 0.934 – 1.12 0.649 574 5709 exclusion phecode
781.1 Loss of height Symptoms 1.22 0.825 – 1.8 0.321 35 214 exclusion phecode
781.2 Abnormal posture Symptoms 0.85 0.458 – 1.58 0.607 14 123 exclusion phecode
782.3 Edema Symptoms 1.18 1.1 – 1.26 3.84e-06 976 8470 exclusion phecode
782.6 Pallor and flushing Symptoms 0.959 0.834 – 1.1 0.553 245 2410 exclusion phecode
783 Fever of unknown origin Symptoms 1.15 1.08 – 1.22 5.44e-06 1350 9562 exclusion phecode
783.1 Postprocedural fever Symptoms 1.23 0.935 – 1.62 0.138 58 642 exclusion phecode
785 Abdominal pain Symptoms 1.04 0.997 – 1.08 0.0666 3950 7061 exclusion phecode
788 Syncope and collapse Symptoms 1.03 0.954 – 1.1 0.498 887 8223 exclusion phecode
789 Nausea and vomiting Symptoms 1.11 1.06 – 1.16 7.12e-06 2685 8302 exclusion phecode
789.1 Persistent vomiting Symptoms 1.3 1.11 – 1.51 0.000778 203 1910 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.08 0.98 – 1.19 0.123 499 4987 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.04 0.76 – 1.42 0.813 42 564 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.06 1 – 1.13 0.0386 1441 9098 exclusion phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.02 0.755 – 1.38 0.893 46 771 exclusion phecode
790.9 Abnormal arterial blood gases Symptoms 1.13 0.765 – 1.68 0.534 27 339 exclusion phecode
791 Gangrene Symptoms 1.16 0.911 – 1.47 0.229 77 589 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 1.05 0.976 – 1.14 0.184 885 4183 exclusion phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 1.08 0.964 – 1.21 0.184 370 2793 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.03 0.831 – 1.28 0.78 96 1118 exclusion phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 1.09 1 – 1.19 0.0506 639 5303 exclusion phecode
795.8 Abnormal tumor markers Symptoms 0.951 0.84 – 1.08 0.43 295 2567 exclusion phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 0.858 0.475 – 1.55 0.611 11 129 exclusion phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 1.09 0.822 – 1.45 0.545 59 490 exclusion phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.787 0.69 – 0.898 0.000378 314 1514 exclusion phecode
797 Shock Symptoms 1.22 1 – 1.48 0.0502 129 1151 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.35 0.974 – 1.88 0.0713 54 436 exclusion phecode
798 Malaise and fatigue Symptoms 1.07 1.02 – 1.12 0.00668 2655 8349 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1.01 0.908 – 1.13 0.822 383 4177 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.09 0.994 – 1.19 0.0663 595 5364 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.19 0.988 – 1.42 0.0668 151 1086 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.12 0.957 – 1.3 0.161 192 1460 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.19 1.03 – 1.38 0.0154 221 2131 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.894 0.726 – 1.1 0.294 105 871 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.03 0.941 – 1.13 0.498 536 5414 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.07 0.936 – 1.23 0.315 249 2719 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.01 0.828 – 1.23 0.93 123 885 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 1 0.919 – 1.09 0.949 608 4860 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1.09 0.924 – 1.28 0.309 177 1770 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.996 0.888 – 1.12 0.946 360 2789 exclusion phecode
803.21 Colles' fracture Injuries & Poisonings 0.898 0.713 – 1.13 0.362 93 688 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.953 0.814 – 1.12 0.548 176 1228 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.994 0.902 – 1.1 0.909 491 3985 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.07 0.949 – 1.2 0.282 347 2856 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 0.903 0.77 – 1.06 0.209 177 1371 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.01 0.941 – 1.09 0.701 829 6736 exclusion phecode
816 Cerebral laceration and contusion Injuries & Poisonings 1.58 0.897 – 2.77 0.114 16 101 exclusion phecode
817 Concussion Injuries & Poisonings 1.05 0.918 – 1.2 0.491 258 2679 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.18 0.94 – 1.49 0.151 85 688 exclusion phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 1.16 0.739 – 1.83 0.511 24 189 exclusion phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.03 0.639 – 1.65 0.908 24 203 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.09 1 – 1.19 0.0498 607 5516 exclusion phecode
830 Dislocation Injuries & Poisonings 0.927 0.861 – 0.997 0.0423 868 8371 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.913 0.827 – 1.01 0.0738 465 5322 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.965 0.758 – 1.23 0.771 80 1028 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.939 0.89 – 0.991 0.021 1782 9030 exclusion phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.895 0.708 – 1.13 0.353 82 1115 exclusion phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.921 0.803 – 1.05 0.234 253 3256 exclusion phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.899 0.83 – 0.974 0.009 746 6296 exclusion phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.917 0.815 – 1.03 0.151 339 3848 exclusion phecode
842 Other sprains and strains Injuries & Poisonings 1.02 0.907 – 1.15 0.739 334 3490 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.12 1.02 – 1.24 0.021 461 4470 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.26 1.16 – 1.37 4.44e-08 669 5863 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.31 1.07 – 1.61 0.0101 107 959 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.21 1.09 – 1.35 0.000302 412 4147 exclusion phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.05 0.793 – 1.4 0.722 54 619 exclusion phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.22 0.912 – 1.63 0.181 59 578 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.11 0.972 – 1.26 0.125 269 3092 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.12 1.02 – 1.23 0.0195 517 5130 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.19 1.08 – 1.3 0.000191 567 4779 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.4 0.977 – 1.99 0.0667 40 366 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.07 0.999 – 1.15 0.0534 997 8403 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.3 0.971 – 1.75 0.0777 55 444 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 0.768 0.548 – 1.08 0.126 41 324 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.97 0.868 – 1.08 0.593 392 3010 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.955 0.725 – 1.26 0.747 60 476 exclusion phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 1.16 0.919 – 1.46 0.212 93 604 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.931 0.716 – 1.21 0.595 64 395 exclusion phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.25 0.878 – 1.78 0.217 38 391 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.06 0.98 – 1.14 0.153 808 7420 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.941 0.782 – 1.13 0.517 128 1282 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.895 0.779 – 1.03 0.115 233 2284 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.33 1.06 – 1.68 0.0147 85 951 exclusion phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.33 0.969 – 1.83 0.0772 44 583 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.19 0.971 – 1.45 0.0944 109 1075 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.39 0.967 – 1.99 0.0759 34 304 exclusion phecode
875 Non-healing surgical wound Injuries & Poisonings 1.09 0.902 – 1.32 0.375 127 1275 exclusion phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.03 0.873 – 1.23 0.697 148 1736 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.1 0.961 – 1.27 0.161 237 2291 exclusion phecode
910 Superficial injury, infected Injuries & Poisonings 0.849 0.538 – 1.34 0.484 22 268 exclusion phecode
911 Blister Injuries & Poisonings 1.1 0.813 – 1.49 0.537 50 571 exclusion phecode
912 Insect bite Injuries & Poisonings 1 0.815 – 1.23 0.992 112 1187 exclusion phecode
913 Toxic effect of venom Injuries & Poisonings 0.753 0.602 – 0.942 0.013 85 744 exclusion phecode
916 Contusion Injuries & Poisonings 1.06 0.991 – 1.14 0.0875 987 8993 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.982 0.84 – 1.15 0.824 184 2047 exclusion phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.899 0.752 – 1.08 0.246 149 1629 exclusion phecode
938 Dermatitis due to solar radiation Dermatologic 0.878 0.824 – 0.935 4.87e-05 1328 6321 exclusion phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.907 0.669 – 1.23 0.529 48 508 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.867 0.813 – 0.925 1.42e-05 1269 6176 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.964 0.909 – 1.02 0.225 1492 7699 exclusion phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 1 0.682 – 1.48 0.982 28 224 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.14 0.796 – 1.63 0.475 37 380 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.27 0.977 – 1.65 0.0746 76 617 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.929 0.766 – 1.13 0.457 125 1147 exclusion phecode
947 Urticaria Dermatologic 1.02 0.897 – 1.15 0.795 287 2944 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.02 0.965 – 1.08 0.467 1617 7675 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.17 0.95 – 1.43 0.143 107 1049 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.701 0.487 – 1.01 0.0546 34 324 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.01 0.899 – 1.15 0.812 305 2721 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 0.782 0.547 – 1.12 0.176 38 329 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.24 0.854 – 1.82 0.255 34 249 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.23 1.12 – 1.35 1.14e-05 552 5167 exclusion phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 1.27 0.997 – 1.62 0.0528 88 767 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.24 1.1 – 1.4 0.000287 342 3712 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.28 1.07 – 1.54 0.00819 138 1185 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.23 1.07 – 1.42 0.00341 233 2385 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.11 0.94 – 1.31 0.22 172 1659 exclusion phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.09 0.865 – 1.38 0.457 84 794 exclusion phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 1.47 0.798 – 2.7 0.217 11 118 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.843 – 1.3 0.682 99 974 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.17 1.08 – 1.27 0.000248 662 5444 exclusion phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.17 1.08 – 1.28 0.000231 644 5337 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.17 0.969 – 1.42 0.102 129 1472 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.18 0.964 – 1.44 0.11 120 1391 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.17 1.01 – 1.37 0.0389 199 2115 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.33 1.17 – 1.5 6.37e-06 303 3397 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.13 0.75 – 1.71 0.558 27 247 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.31 0.851 – 2.02 0.22 28 229 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.02 0.9 – 1.16 0.751 305 2905 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.47 1.13 – 1.92 0.0038 74 697 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.49 0.903 – 2.46 0.118 18 124 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.34 0.992 – 1.8 0.0562 51 576 exclusion phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 1.23 0.758 – 1.99 0.404 13 157 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.88 1.09 – 3.25 0.0232 16 198 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.55 0.959 – 2.51 0.0736 21 234 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.916 0.543 – 1.55 0.743 14 199 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.02 0.59 – 1.75 0.953 15 160 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.12 0.998 – 1.25 0.0535 383 3849 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.18 1.09 – 1.27 3.49e-05 797 7171 exclusion phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 1.05 0.928 – 1.19 0.425 288 2809 exclusion phecode
985 Toxic effect of other metals Injuries & Poisonings 1.73 0.909 – 3.3 0.0948 17 92 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.36 0.938 – 1.98 0.105 34 302 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.14 1.06 – 1.22 0.00042 954 6503 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.23 1.11 – 1.36 6.99e-05 461 4485 exclusion phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.11 0.856 – 1.44 0.43 74 650 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.22 1.1 – 1.35 0.000231 429 4266 exclusion phecode
994.21 Septic shock Injuries & Poisonings 1.19 0.992 – 1.44 0.0602 138 1270 exclusion phecode
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