Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Body mass index Michigan Genomics Initiative Freeze 3 (MGI) PheWAS analysis

Body mass index — Michigan Genomics Initiative Freeze 3 (MGI) PRS PheWAS

PRS model
PRS ID exprsweb-bmi-23104-raw-dbslmm-mgi-freeze3-20211120Legacy DBSLMMDBSLMMUK Biobank GWAS

Evaluation cohort: Michigan Genomics Initiative Freeze 3 (MGI).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: normal-range subset (18.5-24.9).

For this ExPRS, the exclusion sensitivity scan keeps only the study's normal-range subset for Body mass index (18.5-24.9) before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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661 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.05 1.01 – 1.09 0.0166 3004 29292 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.12 1.05 – 1.19 0.000196 1322 13162 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.1 1.03 – 1.18 0.00371 1046 10455 all phecode
008.6 Viral Enteritis Infectious Diseases 1.1 1.02 – 1.18 0.0182 770 7676 all phecode
010 Tuberculosis Infectious Diseases 1.08 0.942 – 1.23 0.281 244 2425 all phecode
031 Diseases due to other mycobacteria Infectious Diseases 1.04 0.827 – 1.31 0.73 86 855 all phecode
038 Septicemia Infectious Diseases 1.14 1.09 – 1.19 9.06e-10 2582 24779 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.14 1.04 – 1.25 0.00438 568 5629 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.24 1.09 – 1.43 0.00175 235 2350 all phecode
038.3 Bacteremia Infectious Diseases 1.15 1.08 – 1.22 8.48e-06 1210 12079 all phecode
041 Bacterial infection NOS Infectious Diseases 1.11 1.08 – 1.14 7.03e-13 5750 38799 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.19 1.13 – 1.25 5.94e-11 1707 16977 all phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.22 1.14 – 1.31 1.15e-08 920 9192 all phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.21 1.12 – 1.3 1.26e-06 783 7812 all phecode
041.2 Streptococcus infection Infectious Diseases 1.13 1.07 – 1.19 8.76e-06 1632 16287 all phecode
041.21 Rheumatic fever / chorea Infectious Diseases 1.06 0.927 – 1.21 0.401 257 2554 all phecode
041.4 E. coli Infectious Diseases 1.11 1.04 – 1.18 0.00153 1175 11680 all phecode
041.8 H. pylori Infectious Diseases 1.23 1.07 – 1.41 0.00354 257 2521 all phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.24 1.11 – 1.38 0.000101 387 3864 all phecode
053 Herpes zoster Infectious Diseases 0.947 0.897 – 0.999 0.0478 1560 15184 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.899 0.779 – 1.04 0.145 220 2169 all phecode
054 Herpes simplex Infectious Diseases 0.945 0.896 – 0.997 0.038 1593 15600 all phecode
070 Viral hepatitis Infectious Diseases 1.07 0.992 – 1.15 0.079 829 8280 all phecode
070.1 Viral hepatitis A Infectious Diseases 0.945 0.756 – 1.18 0.616 87 860 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.05 0.91 – 1.21 0.499 215 2138 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.12 1.02 – 1.23 0.0159 528 5280 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.03 0.881 – 1.19 0.746 197 1964 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.05 0.983 – 1.11 0.153 1145 11381 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.07 0.904 – 1.27 0.418 145 1450 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.06 0.876 – 1.28 0.553 117 1163 all phecode
078 Viral warts & HPV Infectious Diseases 0.935 0.902 – 0.97 0.000326 3434 29624 all phecode
079 Viral infection Infectious Diseases 0.964 0.938 – 0.99 0.00754 6664 35342 all phecode
079.1 Varicella infection Infectious Diseases 0.915 0.883 – 0.947 5.53e-07 3793 31251 all phecode
079.2 Infectious mononucleosis Infectious Diseases 0.907 0.8 – 1.03 0.127 283 2723 all phecode
079.9 Viremia, NOS Infectious Diseases 1.04 0.965 – 1.12 0.312 838 8253 all phecode
080 Postoperative infection Infectious Diseases 1.16 1.11 – 1.21 3.64e-12 2619 26065 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.14 1.08 – 1.2 1.08e-06 1589 15884 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1 0.937 – 1.07 0.944 965 9630 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.05 1.01 – 1.08 0.0166 3544 30054 all phecode
110.1 Dermatophytosis Infectious Diseases 1.05 1.01 – 1.09 0.00785 3241 27244 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.06 1.01 – 1.11 0.027 2044 16765 all phecode
110.12 Althete's foot Infectious Diseases 1.08 1 – 1.16 0.0456 899 8043 all phecode
110.13 Dermatophytosis of the body Infectious Diseases 1.09 1.01 – 1.18 0.0244 790 7827 all phecode
110.2 Dermatomycoses Infectious Diseases 0.987 0.888 – 1.1 0.805 398 3971 all phecode
112 Candidiasis Infectious Diseases 1.08 1.04 – 1.11 5.02e-05 3685 30495 all phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.22 1.13 – 1.33 9.65e-07 682 6732 all phecode
117 Mycoses Infectious Diseases 1.04 0.959 – 1.14 0.313 608 6069 all phecode
117.1 Histoplasmosis Infectious Diseases 0.953 0.754 – 1.2 0.687 81 801 all phecode
117.4 Aspergillosis Infectious Diseases 1.1 0.919 – 1.31 0.3 140 1387 all phecode
130 Spirochetal infection Infectious Diseases 0.947 0.805 – 1.11 0.508 168 1677 all phecode
130.1 Lyme disease Infectious Diseases 0.904 0.742 – 1.1 0.315 116 1160 all phecode
131 Protozoan infection Infectious Diseases 1.21 0.938 – 1.55 0.144 61 610 all phecode
132 Infestation (lice, mites) Infectious Diseases 1.18 1.01 – 1.36 0.0324 195 1948 all phecode
134 Helminthiases Infectious Diseases 1.08 0.858 – 1.36 0.506 83 812 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.17 0.871 – 1.56 0.302 53 513 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.06 1.02 – 1.1 0.00119 3279 32486 all phecode
145 Cancer of mouth Neoplasms 1.01 0.96 – 1.07 0.613 1481 14725 all phecode
145.1 Cancer of lip Neoplasms 1.15 0.912 – 1.45 0.236 76 750 all phecode
145.2 Cancer of tongue Neoplasms 0.985 0.907 – 1.07 0.712 645 6430 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.01 0.901 – 1.13 0.898 361 3597 all phecode
145.4 Cancer of the gums Neoplasms 1.03 0.875 – 1.22 0.697 166 1632 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.09 0.938 – 1.26 0.268 206 2048 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.01 0.948 – 1.07 0.854 1290 12873 all phecode
149.1 Cancer of oropharynx Neoplasms 1.04 0.93 – 1.16 0.492 350 3499 all phecode
149.2 Cancer of nasopharynx Neoplasms 0.996 0.805 – 1.23 0.968 100 1000 all phecode
149.3 Cancer of hypopharynx Neoplasms 0.843 0.666 – 1.07 0.154 82 819 all phecode
149.4 Cancer of larynx Neoplasms 1.06 0.951 – 1.18 0.293 386 3857 all phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 1.07 0.978 – 1.17 0.142 552 5505 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.86 0.752 – 0.983 0.0275 240 2398 all phecode
150 Cancer of esophagus Neoplasms 1.24 1.12 – 1.37 2.79e-05 433 4315 all phecode
151 Cancer of stomach Neoplasms 1.13 1.02 – 1.24 0.014 498 4962 all phecode
153 Colorectal cancer Neoplasms 1.04 0.981 – 1.1 0.198 1458 14383 all phecode
153.2 Colon cancer Neoplasms 1.05 0.984 – 1.11 0.144 1160 11472 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.975 0.905 – 1.05 0.5 815 8093 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.07 0.974 – 1.18 0.161 511 5097 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.08 0.959 – 1.2 0.213 344 3433 all phecode
157 Pancreatic cancer Neoplasms 0.995 0.904 – 1.09 0.911 503 5005 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.05 0.992 – 1.1 0.0941 1623 15759 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.04 0.987 – 1.09 0.146 1818 17869 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.02 0.891 – 1.18 0.734 221 2206 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.09 0.924 – 1.29 0.297 158 1578 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.03 0.912 – 1.17 0.615 293 2920 all phecode
164 Cancer of intrathoracic organs Neoplasms 0.899 0.752 – 1.07 0.24 133 1324 all phecode
165 Cancer within the respiratory system Neoplasms 1.05 0.989 – 1.11 0.114 1336 13340 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.04 0.976 – 1.11 0.219 1057 10552 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.96 0.913 – 1.01 0.106 1792 17850 all phecode
170.1 Bone cancer Neoplasms 0.959 0.889 – 1.03 0.278 773 7690 all phecode
170.2 Cancer of connective tissue Neoplasms 0.964 0.908 – 1.02 0.218 1266 12632 all phecode
172 Skin cancer Neoplasms 0.942 0.918 – 0.966 4.43e-06 8608 33186 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.929 0.901 – 0.958 2.99e-06 5330 30106 all phecode
172.11 Melanomas of skin Neoplasms 0.931 0.896 – 0.968 0.000297 3100 25064 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.938 0.913 – 0.965 7.01e-06 7095 30462 all phecode
172.21 Basal cell carcinoma Neoplasms 0.888 0.856 – 0.921 1.7e-10 3690 23868 all phecode
172.22 Squamous cell carcinoma Neoplasms 0.984 0.941 – 1.03 0.479 2414 17683 all phecode
172.3 Carcinoma in situ of skin Neoplasms 0.909 0.86 – 0.962 0.000927 1482 12326 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.928 0.885 – 0.974 0.00223 1997 18755 all phecode
174 Breast cancer Neoplasms 0.914 0.878 – 0.952 1.22e-05 3186 15514 all phecode
174.1 Breast cancer [female] Neoplasms 0.913 0.877 – 0.952 1.66e-05 3036 14701 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.914 0.877 – 0.953 2.3e-05 2991 14639 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.877 0.765 – 1.01 0.0627 233 2307 all phecode
175 Acquired absence of breast Neoplasms 0.931 0.867 – 0.999 0.0468 919 8920 all phecode
180 Cervical cancer and dysplasia Neoplasms 0.987 0.933 – 1.04 0.652 1431 12185 all phecode
180.1 Cervical cancer Neoplasms 1.06 0.967 – 1.17 0.208 500 4982 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.953 0.892 – 1.02 0.15 1048 9323 all phecode
182 Malignant neoplasm of uterus Neoplasms 1.11 1.03 – 1.2 0.00646 765 7613 all phecode
184 Cancer of other female genital organs Neoplasms 1.04 0.976 – 1.1 0.233 1191 11592 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.01 0.924 – 1.1 0.831 573 5719 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.975 0.881 – 1.08 0.626 432 4309 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.11 1.02 – 1.21 0.0192 608 6057 all phecode
185 Cancer of prostate Neoplasms 0.932 0.891 – 0.974 0.00176 2901 10342 all phecode
187 Cancer of other male genital organs Neoplasms 0.94 0.839 – 1.05 0.29 339 3384 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.971 0.798 – 1.18 0.766 115 1141 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.935 0.802 – 1.09 0.388 183 1830 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.851 0.645 – 1.12 0.255 57 562 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.12 1.07 – 1.16 5.06e-08 2923 23541 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.12 1.06 – 1.19 6.28e-05 1450 14437 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.14 1.07 – 1.21 2.24e-05 1267 12655 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.1 0.95 – 1.26 0.209 237 2347 all phecode
189.2 Cancer of bladder Neoplasms 1.12 1.07 – 1.18 1.01e-05 1783 15224 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.12 1.07 – 1.18 1.71e-05 1657 14178 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.11 1.02 – 1.2 0.0173 678 6586 all phecode
190 Cancer of eye Neoplasms 0.941 0.786 – 1.13 0.504 138 1374 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.967 0.907 – 1.03 0.313 1078 10771 all phecode
191.1 Cancer of brain and nervous system Neoplasms 0.936 0.865 – 1.01 0.101 706 7052 all phecode
191.11 Cancer of brain Neoplasms 0.929 0.853 – 1.01 0.0916 600 5996 all phecode
193 Thyroid cancer Neoplasms 0.993 0.926 – 1.06 0.837 945 9393 all phecode
194 Cancer of other endocrine glands Neoplasms 1.02 0.937 – 1.12 0.609 579 5759 all phecode
195 Cancer, suspected or other Neoplasms 1.01 0.986 – 1.03 0.48 16962 26401 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.01 0.984 – 1.03 0.643 16670 26384 all phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1.01 0.947 – 1.08 0.771 1103 9766 all phecode
196 Radiotherapy Neoplasms 0.96 0.918 – 1 0.0688 2427 17006 all phecode
197 Chemotherapy Neoplasms 1.01 0.981 – 1.05 0.418 4952 23797 all phecode
198 Secondary malignant neoplasm Neoplasms 1.02 0.987 – 1.05 0.253 5801 23481 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.991 0.955 – 1.03 0.611 3677 21489 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.05 0.985 – 1.12 0.136 1072 10334 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.06 0.991 – 1.14 0.0849 866 8538 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.03 0.958 – 1.12 0.39 767 7558 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.943 0.867 – 1.03 0.173 640 6338 all phecode
198.6 Secondary malignancy of bone Neoplasms 0.96 0.893 – 1.03 0.263 866 8307 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.918 0.819 – 1.03 0.143 336 3253 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.01 0.975 – 1.04 0.745 5693 25767 all phecode
199.4 Neurofibromatosis Neoplasms 0.918 0.743 – 1.13 0.427 88 880 all phecode
200 Myeloproliferative disease Neoplasms 1.04 0.977 – 1.11 0.213 1113 11098 all phecode
200.1 Polycythemia vera Neoplasms 1.11 0.962 – 1.27 0.157 231 2310 all phecode
201 Hodgkin's disease Neoplasms 1.15 0.982 – 1.35 0.0826 172 1705 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.03 0.98 – 1.09 0.228 1559 15571 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.03 0.97 – 1.09 0.345 1329 13268 all phecode
202.21 Nodular lymphoma Neoplasms 1 0.925 – 1.09 0.944 693 6923 all phecode
202.22 Reticulosarcoma Neoplasms 1.13 0.963 – 1.32 0.135 170 1693 all phecode
202.24 Large cell lymphoma Neoplasms 1.09 0.921 – 1.29 0.322 160 1586 all phecode
204 Leukemia Neoplasms 1.04 0.958 – 1.13 0.347 689 6876 all phecode
204.1 Lymphoid leukemia Neoplasms 0.979 0.852 – 1.12 0.762 236 2354 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.86 0.674 – 1.1 0.224 74 734 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.01 0.858 – 1.19 0.903 173 1724 all phecode
204.2 Myeloid leukemia Neoplasms 1.05 0.921 – 1.2 0.461 265 2633 all phecode
204.21 Myeloid leukemia, acute Neoplasms 1.06 0.893 – 1.26 0.501 153 1516 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.992 0.752 – 1.31 0.956 61 610 all phecode
204.4 Multiple myeloma Neoplasms 1.15 0.997 – 1.33 0.0557 217 2162 all phecode
208 Benign neoplasm of colon Neoplasms 0.994 0.971 – 1.02 0.583 10303 34953 all phecode
209 Neuroendocrine tumors Neoplasms 1.01 0.885 – 1.15 0.898 258 2580 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.963 0.917 – 1.01 0.124 1891 18839 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.08 1.05 – 1.11 3.28e-09 7329 36606 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.04 0.99 – 1.09 0.115 1843 18412 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.981 0.931 – 1.03 0.459 1677 15527 all phecode
214 Lipoma Neoplasms 0.973 0.92 – 1.03 0.341 1437 14132 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.956 0.889 – 1.03 0.219 883 8710 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.01 0.977 – 1.04 0.611 4528 39509 all phecode
216 Benign neoplasm of skin Neoplasms 0.93 0.91 – 0.951 8.21e-11 11528 34919 all phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 0.897 0.764 – 1.05 0.181 174 1701 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.884 0.84 – 0.93 2.01e-06 1786 17184 all phecode
217.1 Nevus, non-neoplastic Neoplasms 0.881 0.836 – 0.929 2.31e-06 1679 16116 all phecode
218 Benign neoplasm of uterus Neoplasms 0.988 0.954 – 1.02 0.496 4301 16661 all phecode
218.1 Uterine leiomyoma Neoplasms 0.973 0.925 – 1.02 0.282 1835 15733 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.985 0.947 – 1.02 0.427 3403 16447 all phecode
220 Benign neoplasm of ovary Neoplasms 1.02 0.947 – 1.09 0.632 893 8783 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.02 0.97 – 1.07 0.474 2042 14248 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.912 0.857 – 0.971 0.00401 1133 10663 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.05 1 – 1.11 0.0468 1801 12657 all phecode
224 Benign neoplasm of eye Neoplasms 0.951 0.877 – 1.03 0.219 691 6752 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.934 0.857 – 1.02 0.127 595 5773 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.02 0.96 – 1.08 0.513 1209 12074 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.01 0.94 – 1.08 0.855 947 9454 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.05 0.922 – 1.19 0.49 289 2890 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.02 0.963 – 1.08 0.493 1329 13264 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.02 0.967 – 1.07 0.502 1690 16896 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.16 1.05 – 1.28 0.00257 467 4644 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.93 0.862 – 1 0.0573 795 7941 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.03 0.928 – 1.14 0.611 435 4350 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.898 0.858 – 0.941 4.98e-06 2149 20946 all phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.883 0.833 – 0.935 2.62e-05 1356 13336 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.982 0.958 – 1.01 0.166 7767 36615 all phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.984 0.956 – 1.01 0.263 5743 34218 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.07 1 – 1.15 0.0393 1031 9761 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.04 0.999 – 1.08 0.053 2910 22227 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.03 0.987 – 1.08 0.159 2265 19902 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.04 0.979 – 1.1 0.207 1304 12479 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.05 0.995 – 1.12 0.0739 1400 13425 all phecode
242.1 Graves' disease Endocrine/metabolic 1 0.914 – 1.1 0.929 515 5068 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.09 0.897 – 1.32 0.393 124 1224 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.03 0.914 – 1.17 0.599 292 2898 all phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.987 0.828 – 1.18 0.884 144 1432 all phecode
244 Hypothyroidism Endocrine/metabolic 1.06 1.03 – 1.09 6.17e-06 8099 32717 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.992 0.943 – 1.04 0.751 1762 17230 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.07 1.01 – 1.14 0.0228 1261 11982 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.06 1.03 – 1.09 1.17e-05 7542 32208 all phecode
245 Thyroiditis Endocrine/metabolic 1.06 0.983 – 1.14 0.13 832 7882 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.06 0.979 – 1.15 0.15 686 6517 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.05 0.968 – 1.14 0.24 679 6449 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.05 1.02 – 1.08 0.00164 6129 30240 all phecode
246.2 Thyroid cyst Endocrine/metabolic 1.04 0.844 – 1.29 0.687 101 960 all phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1.02 0.951 – 1.1 0.558 886 8696 all phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.28 1.19 – 1.37 2.77e-11 1150 8340 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.22 1.2 – 1.25 6.15e-70 13947 31815 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.29 1.21 – 1.37 4.23e-16 2364 11758 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.09 0.918 – 1.31 0.313 262 960 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.18 1.04 – 1.33 0.00734 551 2686 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.18 1.06 – 1.31 0.00288 784 3018 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.2 1.07 – 1.35 0.00233 638 2675 all phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 1.13 0.92 – 1.4 0.239 155 850 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.3 1.27 – 1.34 5.85e-88 9843 29688 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.21 1.04 – 1.41 0.015 282 1327 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.44 1.36 – 1.53 3.01e-36 1941 13510 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.37 1.28 – 1.46 2.39e-20 1643 9668 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.42 1.35 – 1.49 7.14e-41 2557 16502 all phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.45 1.33 – 1.58 2.5e-18 860 6143 all phecode
250.3 Insulin pump user Endocrine/metabolic 1.39 1.33 – 1.45 1.53e-46 3496 20809 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.15 1.12 – 1.18 1.79e-22 8385 30645 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.11 1.06 – 1.17 5.02e-05 1870 15861 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.15 1.12 – 1.19 4.57e-22 7553 30071 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.23 1.02 – 1.49 0.0343 136 1067 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.42 1.34 – 1.51 2.07e-33 2132 13390 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.19 1.13 – 1.26 1.24e-09 1691 10517 all phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.1 1.02 – 1.17 0.00752 991 8469 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.18 1.1 – 1.27 2.81e-06 1207 8570 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.09 1.04 – 1.13 0.000342 2282 22119 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.08 1.03 – 1.13 0.00161 2088 20335 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.05 0.96 – 1.16 0.271 508 5073 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.04 0.968 – 1.12 0.285 859 8544 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.08 0.954 – 1.23 0.219 263 2621 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.04 0.829 – 1.3 0.744 83 826 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.04 0.903 – 1.19 0.603 226 2250 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.09 0.872 – 1.37 0.438 86 860 all phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 1.07 0.885 – 1.29 0.486 121 1209 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.03 0.846 – 1.26 0.747 108 1080 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.14 1.08 – 1.2 2.91e-06 1506 14869 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.02 0.91 – 1.13 0.786 373 3730 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.987 0.847 – 1.15 0.872 183 1830 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.984 0.82 – 1.18 0.867 135 1350 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.05 0.965 – 1.14 0.259 626 6239 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.05 0.958 – 1.14 0.318 596 5941 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.13 1.06 – 1.2 0.000144 1146 10513 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.28 1.19 – 1.39 5.33e-10 742 7128 all phecode
257 Testicular dysfunction Endocrine/metabolic 1.02 0.953 – 1.09 0.592 1015 9238 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.01 0.946 – 1.08 0.734 983 8933 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.15 0.929 – 1.42 0.202 91 910 all phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.972 0.793 – 1.19 0.785 109 1090 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.05 0.983 – 1.12 0.148 1038 10259 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.05 1.01 – 1.09 0.0135 2880 26812 all phecode
260.1 Cachexia Endocrine/metabolic 1.01 0.89 – 1.14 0.91 292 2911 all phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.07 1.02 – 1.13 0.00751 1691 16847 all phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.13 1.03 – 1.23 0.00669 614 6140 all phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.05 0.963 – 1.14 0.274 629 6236 all phecode
260.6 Anorexia Endocrine/metabolic 1.05 0.98 – 1.13 0.16 868 8591 all phecode
260.7 Polyphagia Endocrine/metabolic 1.07 0.817 – 1.4 0.628 65 643 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.12 1.09 – 1.15 1.39e-16 7718 35203 all phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1.09 0.847 – 1.41 0.496 69 690 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.22 1.14 – 1.31 6.39e-08 857 8405 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.11 1.09 – 1.15 1.88e-15 7255 35225 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.01 0.747 – 1.36 0.958 52 511 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.16 1.09 – 1.23 4.87e-06 1182 11676 all phecode
263 Other nutritional deficiency Endocrine/metabolic 1.07 1.01 – 1.12 0.0168 1651 15788 all phecode
264 Lack of normal physiological development Endocrine/metabolic 0.964 0.843 – 1.1 0.596 239 2301 all phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 0.91 0.757 – 1.09 0.317 122 1220 all phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 0.963 0.772 – 1.2 0.736 81 772 all phecode
269 Proteinuria Endocrine/metabolic 1.23 1.17 – 1.3 5.4e-15 1694 13981 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.07 0.996 – 1.14 0.0657 967 9575 all phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 1.01 0.861 – 1.2 0.866 170 1697 all phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 1.08 0.896 – 1.29 0.429 134 1334 all phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 1.23 1 – 1.51 0.0484 96 954 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.04 0.966 – 1.13 0.273 737 7303 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.08 0.971 – 1.2 0.155 384 3781 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.02 0.797 – 1.32 0.851 71 695 all phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 0.859 0.666 – 1.11 0.241 69 690 all phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.03 0.915 – 1.17 0.6 299 2984 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.03 0.986 – 1.07 0.199 2907 28132 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.02 0.978 – 1.06 0.372 2827 27425 all phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.17 0.96 – 1.43 0.12 102 1007 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.09 1.07 – 1.11 5.52e-16 18881 26670 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.09 1.07 – 1.12 4.63e-16 18843 26654 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.05 1.02 – 1.08 0.00238 5928 21600 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.12 1.06 – 1.19 0.000159 1360 11837 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.11 1.07 – 1.16 8.84e-08 3538 18449 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.953 0.845 – 1.08 0.436 313 3011 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.14 1.09 – 1.19 8.82e-10 2524 22729 all phecode
274.1 Gout Endocrine/metabolic 1.15 1.1 – 1.2 1.58e-10 2409 21991 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.12 1.05 – 1.2 0.00037 1082 10576 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.966 0.828 – 1.13 0.658 195 1890 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.952 0.813 – 1.12 0.545 183 1772 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.08 1.05 – 1.12 3.53e-06 4357 37091 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.891 0.771 – 1.03 0.114 218 2180 all phecode
275.11 Hereditary hemochromatosis Hematopoietic 0.921 0.745 – 1.14 0.449 99 990 all phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 0.967 0.749 – 1.25 0.796 62 614 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.13 1.06 – 1.2 0.000153 1154 11504 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.08 1.04 – 1.12 5.43e-05 3369 31544 all phecode
275.51 Hypocalcemia Endocrine/metabolic 1.08 1.01 – 1.16 0.028 898 8969 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.1 1.04 – 1.17 0.000817 1366 13634 all phecode
275.6 Hypercalcemia Endocrine/metabolic 1.04 0.981 – 1.1 0.199 1468 14183 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.1 1.08 – 1.13 3.45e-16 9238 37046 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.11 1.08 – 1.15 5.24e-14 6352 34366 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.12 1.03 – 1.23 0.0118 550 5434 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.09 1.04 – 1.13 0.000135 2514 23219 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.18 1.13 – 1.22 3.81e-16 2992 25216 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.08 1.03 – 1.13 0.00156 2148 20909 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.14 1.08 – 1.19 8.33e-08 2086 20332 all phecode
276.41 Acidosis Endocrine/metabolic 1.14 1.08 – 1.2 4.32e-07 1788 17572 all phecode
276.42 Alkalosis Endocrine/metabolic 1.15 1.04 – 1.27 0.00426 476 4741 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.1 1.07 – 1.14 1.61e-09 4574 34527 all phecode
276.6 Fluid overload Endocrine/metabolic 1.26 1.19 – 1.33 4.49e-15 1384 13211 all phecode
276.8 Polydipsia Endocrine/metabolic 0.967 0.805 – 1.16 0.722 124 1240 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.11 1.07 – 1.15 9.91e-10 4112 35070 all phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.37 1.23 – 1.52 6.98e-09 403 3991 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.993 0.918 – 1.07 0.857 720 7161 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.1 1.02 – 1.18 0.00916 936 9270 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.14 1.05 – 1.23 0.000917 773 7668 all phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.27 1.19 – 1.37 1.87e-11 916 8359 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.49 1.46 – 1.52 1.87e-327 19419 27331 all phecode
278.1 Obesity Endocrine/metabolic 1.56 1.53 – 1.6 3.56e-378 17129 27321 all phecode
278.11 Morbid obesity Endocrine/metabolic 1.8 1.75 – 1.85 2.73e-377 8280 27172 all phecode
278.3 Localized adiposity Endocrine/metabolic 1.67 1.48 – 1.88 7.28e-17 324 3228 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.31 1.25 – 1.37 3.75e-28 2104 17411 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.04 1 – 1.08 0.0409 2934 28612 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1.03 0.964 – 1.09 0.43 1161 11571 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.01 0.903 – 1.14 0.83 330 3278 all phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 1.04 0.962 – 1.12 0.331 754 7516 all phecode
279.7 Other immunological findings Endocrine/metabolic 0.992 0.962 – 1.02 0.627 4885 36552 all phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 0.993 0.911 – 1.08 0.869 601 5988 all phecode
280 Iron deficiency anemias Hematopoietic 1.11 1.08 – 1.15 5.47e-11 4626 30873 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.11 1.08 – 1.15 7.26e-11 4484 30649 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.1 1.04 – 1.15 0.000321 1771 17196 all phecode
281 Other deficiency anemia Hematopoietic 1.02 0.925 – 1.11 0.746 519 5120 all phecode
281.1 Megaloblastic anemia Hematopoietic 0.999 0.874 – 1.14 0.99 253 2497 all phecode
281.11 Pernicious anemia Hematopoietic 1.16 0.949 – 1.42 0.146 114 1108 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.988 0.848 – 1.15 0.877 187 1817 all phecode
281.9 Deficiency anemias Hematopoietic 1.06 0.933 – 1.2 0.385 285 2830 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.1 0.976 – 1.23 0.12 323 3188 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.1 0.952 – 1.27 0.198 216 2113 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.13 0.974 – 1.32 0.107 192 1920 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.23 1.04 – 1.45 0.0183 155 1550 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.17 0.903 – 1.53 0.231 64 633 all phecode
284 Aplastic anemia Hematopoietic 1.02 0.94 – 1.1 0.656 697 6943 all phecode
284.1 Pancytopenia Hematopoietic 1.04 0.951 – 1.13 0.418 612 6100 all phecode
285 Other anemias Hematopoietic 1.09 1.07 – 1.12 2.04e-15 11794 33591 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.11 1.07 – 1.15 5.22e-08 3325 27709 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.15 1.1 – 1.21 3.27e-09 2055 19939 all phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.27 1.18 – 1.36 1.81e-11 932 9106 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.03 0.949 – 1.12 0.488 690 6892 all phecode
286 Coagulation defects Hematopoietic 1.07 1.04 – 1.11 8.04e-05 3844 33384 all phecode
286.1 Congenital coagulation defects Hematopoietic 1.06 0.924 – 1.21 0.427 250 2466 all phecode
286.11 Von willebrand's disease Hematopoietic 1.02 0.811 – 1.28 0.88 83 822 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.04 0.866 – 1.24 0.693 126 1260 all phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.09 1.05 – 1.14 2.52e-06 3354 25918 all phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 0.946 0.76 – 1.18 0.623 97 962 all phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 1.08 0.948 – 1.23 0.249 254 2529 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.09 0.91 – 1.3 0.355 132 1294 all phecode
286.6 Defibrination syndrome Hematopoietic 1.08 1.04 – 1.13 0.000307 2579 25377 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.07 1.03 – 1.11 0.000811 3014 29294 all phecode
286.8 Hypercoagulable state Hematopoietic 1.07 0.998 – 1.15 0.0571 846 8437 all phecode
286.81 Primary hypercoagulable state Hematopoietic 1.07 0.996 – 1.16 0.0636 813 8111 all phecode
286.9 Abnormal coagulation profile Hematopoietic 1.1 1.04 – 1.17 0.0018 1182 11487 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.05 1.01 – 1.09 0.00628 3288 28474 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.06 0.92 – 1.22 0.42 211 2094 all phecode
287.3 Thrombocytopenia Hematopoietic 1.05 1.01 – 1.1 0.00824 2938 26323 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.07 0.98 – 1.16 0.134 601 5994 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.03 0.945 – 1.13 0.469 569 5686 all phecode
287.4 Qualitative platelet defects Hematopoietic 1.17 0.961 – 1.43 0.117 112 1120 all phecode
288 Diseases of white blood cells Hematopoietic 1.08 1.05 – 1.11 1.03e-06 4886 36527 all phecode
288.1 Decreased white blood cell count Hematopoietic 1.01 0.959 – 1.07 0.68 1599 15951 all phecode
288.11 Neutropenia Hematopoietic 1.01 0.944 – 1.07 0.861 1106 11041 all phecode
288.2 Elevated white blood cell count Hematopoietic 1.09 1.06 – 1.13 1.07e-07 4082 35079 all phecode
288.3 Eosinophilia Hematopoietic 0.882 0.755 – 1.03 0.112 187 1866 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.06 1.01 – 1.12 0.0211 1757 17434 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.02 0.952 – 1.1 0.55 918 9087 all phecode
289.4 Lymphadenitis Hematopoietic 1.04 1 – 1.07 0.0313 3888 34715 all phecode
289.5 Diseases of spleen Hematopoietic 0.978 0.878 – 1.09 0.691 393 3913 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.12 0.988 – 1.28 0.0766 255 2550 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.14 1.02 – 1.27 0.017 385 3813 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1 0.942 – 1.06 0.995 1318 11547 all phecode
290.1 Dementias Mental Disorders 0.922 0.841 – 1.01 0.0815 541 4910 all phecode
290.11 Alzheimer's disease Mental Disorders 1 0.841 – 1.19 0.993 151 1389 all phecode
290.12 Dementia with cerebral degenerations Mental Disorders 0.88 0.702 – 1.1 0.264 88 846 all phecode
290.13 Senile dementia Mental Disorders 0.9 0.802 – 1.01 0.0747 340 3078 all phecode
290.16 Vascular dementia Mental Disorders 0.923 0.733 – 1.16 0.497 81 777 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.03 0.955 – 1.12 0.421 750 7358 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.945 0.881 – 1.01 0.12 886 8618 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.997 0.956 – 1.04 0.888 2550 24810 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.929 0.793 – 1.09 0.358 175 1750 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.991 0.901 – 1.09 0.848 484 4807 all phecode
291.8 Alteration of consciousness Mental Disorders 1.01 0.962 – 1.06 0.725 2036 19974 all phecode
292 Neurological disorders Mental Disorders 1.01 0.981 – 1.04 0.5 5733 38553 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.976 0.931 – 1.02 0.316 2013 19867 all phecode
292.11 Aphasia Mental Disorders 0.961 0.885 – 1.04 0.348 664 6581 all phecode
292.12 Symbolic dysfunction Mental Disorders 0.998 0.864 – 1.15 0.976 200 1988 all phecode
292.2 Mild cognitive impairment Mental Disorders 1.04 0.929 – 1.15 0.526 389 3731 all phecode
292.3 Memory loss Mental Disorders 0.964 0.919 – 1.01 0.141 1922 18158 all phecode
292.4 Altered mental status Mental Disorders 1.07 1.02 – 1.11 0.00385 2454 22725 all phecode
292.5 Transient alteration of awareness Mental Disorders 0.977 0.884 – 1.08 0.647 430 4285 all phecode
292.6 Hallucinations Mental Disorders 1.06 0.914 – 1.23 0.445 217 2147 all phecode
293 Symptoms involving head and neck Mental Disorders 0.904 0.816 – 1 0.0531 414 4127 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.01 0.975 – 1.04 0.679 4417 38609 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.07 0.995 – 1.15 0.0674 885 8229 all phecode
295.1 Schizophrenia Mental Disorders 0.918 0.764 – 1.1 0.356 138 1339 all phecode
295.2 Paranoid disorders Mental Disorders 1.08 0.893 – 1.32 0.414 118 1079 all phecode
295.3 Psychosis Mental Disorders 1.11 1.03 – 1.2 0.00989 716 6694 all phecode
296 Mood disorders Mental Disorders 1.07 1.05 – 1.09 1.6e-09 15356 20858 all phecode
296.1 Bipolar Mental Disorders 1.09 1.03 – 1.16 0.00446 1301 11264 all phecode
296.2 Depression Mental Disorders 1.07 1.05 – 1.1 9.9e-10 14833 20856 all phecode
296.22 Major depressive disorder Mental Disorders 1.07 1.05 – 1.1 4.2e-09 13850 20853 all phecode
297 Suicidal ideation or attempt Mental Disorders 1.08 1.01 – 1.16 0.0248 985 9050 all phecode
297.1 Suicidal ideation Mental Disorders 1.08 1 – 1.16 0.0468 788 7310 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.01 0.895 – 1.15 0.839 285 2654 all phecode
300 Anxiety disorders Mental Disorders 1.04 1.02 – 1.06 0.000664 15419 20850 all phecode
300.1 Anxiety disorder Mental Disorders 1.04 1.02 – 1.07 0.000209 14517 20855 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1.01 0.983 – 1.05 0.38 5546 20512 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.04 0.983 – 1.11 0.158 1360 11377 all phecode
300.13 Phobia Mental Disorders 1.06 0.989 – 1.13 0.102 1051 9542 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.886 0.788 – 0.996 0.0423 328 3018 all phecode
300.4 Dysthymic disorder Mental Disorders 1.05 1 – 1.09 0.0466 2420 16552 all phecode
300.8 Acute reaction to stress Mental Disorders 1.01 0.918 – 1.12 0.804 504 4825 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.13 1.05 – 1.21 0.00161 843 7909 all phecode
301 Personality disorders Mental Disorders 1.11 1.01 – 1.23 0.0313 477 4539 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.07 0.937 – 1.23 0.311 254 2393 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.986 0.949 – 1.02 0.483 3700 13808 all phecode
302.1 Decreased libido Mental Disorders 0.966 0.875 – 1.07 0.501 447 4331 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.94 0.913 – 0.968 3.51e-05 6808 20043 all phecode
303.1 Dissociative disorder Mental Disorders 1.2 1.02 – 1.41 0.0321 161 1573 all phecode
303.3 Psychogenic disorder Mental Disorders 0.932 0.905 – 0.96 3.8e-06 6487 19888 all phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.89 0.806 – 0.983 0.021 471 4623 all phecode
303.4 Somatoform disorder Mental Disorders 0.99 0.93 – 1.05 0.745 1177 11180 all phecode
304 Adjustment reaction Mental Disorders 1.03 0.993 – 1.07 0.114 3888 20475 all phecode
305.2 Eating disorder Mental Disorders 1.24 1.16 – 1.33 2.64e-09 901 8329 all phecode
306 Other mental disorder Mental Disorders 1.03 0.975 – 1.08 0.317 1815 14133 all phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.02 0.931 – 1.12 0.661 587 3527 all phecode
306.9 Tension headache Mental Disorders 0.964 0.891 – 1.04 0.358 753 7277 all phecode
312 Conduct disorders Mental Disorders 1.06 0.929 – 1.21 0.388 254 2501 all phecode
312.3 Impulse control disorder Mental Disorders 1.09 0.863 – 1.39 0.458 74 736 all phecode
313 Pervasive developmental disorders Mental Disorders 1.01 0.955 – 1.06 0.798 1571 14633 all phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1.01 0.951 – 1.06 0.823 1392 13190 all phecode
313.2 Tics and stuttering Mental Disorders 1 0.794 – 1.26 0.997 77 770 all phecode
313.3 Autism Mental Disorders 1.1 0.843 – 1.43 0.489 64 621 all phecode
315 Develomental delays and disorders Mental Disorders 1.05 0.964 – 1.14 0.278 684 6788 all phecode
315.1 Learning disorder Mental Disorders 0.923 0.741 – 1.15 0.473 87 860 all phecode
315.2 Speech and language disorder Mental Disorders 0.945 0.827 – 1.08 0.405 254 2539 all phecode
316 Substance addiction and disorders Mental Disorders 1.13 1.09 – 1.17 1.47e-11 3682 32680 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.04 0.958 – 1.13 0.341 634 6331 all phecode
317 Alcohol-related disorders Mental Disorders 1.01 0.966 – 1.05 0.715 2525 22920 all phecode
317.1 Alcoholism Mental Disorders 1.01 0.959 – 1.05 0.824 1986 19339 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.03 0.928 – 1.14 0.587 408 4080 all phecode
318 Tobacco use disorder Mental Disorders 1.17 1.15 – 1.2 1.08e-37 8622 34842 all phecode
320 Meningitis Neurological 1.06 0.955 – 1.19 0.26 382 3820 all phecode
323 Encephalitis Neurological 1.01 0.863 – 1.17 0.938 181 1809 all phecode
323.8 Encephalitis, non-infectious Neurological 1.01 0.859 – 1.2 0.863 153 1527 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.08 0.95 – 1.22 0.248 288 2880 all phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 0.975 0.737 – 1.29 0.858 53 530 all phecode
327 Sleep disorders Neurological 1.14 1.12 – 1.16 5.16e-37 14941 31602 all phecode
327.1 Hypersomnia Neurological 1.09 1.04 – 1.14 0.000555 2061 19110 all phecode
327.3 Sleep apnea Neurological 1.21 1.18 – 1.24 4.01e-58 10909 31304 all phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1.1 1 – 1.21 0.0455 492 4784 all phecode
327.32 Obstructive sleep apnea Neurological 1.21 1.18 – 1.25 4.42e-52 8744 30530 all phecode
327.4 Insomnia Neurological 1.05 1.02 – 1.08 0.000955 5524 30960 all phecode
327.41 Organic or persistent insomnia Neurological 1.06 0.998 – 1.13 0.0579 1265 12120 all phecode
327.5 Parasomnia Neurological 1.15 1.06 – 1.26 0.00102 604 5913 all phecode
327.6 Circadian rhythm sleep disorder Neurological 1.02 0.894 – 1.16 0.769 274 2666 all phecode
327.7 Sleep related movement disorders Neurological 1.13 1.08 – 1.19 1.24e-06 1786 17323 all phecode
327.71 Restless legs syndrome Neurological 1.13 1.07 – 1.2 5.1e-06 1570 15360 all phecode
327.72 Sleep related leg cramps Neurological 1.08 0.854 – 1.36 0.533 83 822 all phecode
331 Other cerebral degenerations Neurological 0.947 0.874 – 1.03 0.183 717 7024 all phecode
331.1 Hydrocephalus Neurological 0.96 0.848 – 1.09 0.519 284 2836 all phecode
331.9 Cerebral degeneration, unspecified Neurological 0.952 0.858 – 1.06 0.352 419 4026 all phecode
332 Parkinson's disease Neurological 0.929 0.838 – 1.03 0.162 415 4128 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.04 1 – 1.08 0.0416 2868 26583 all phecode
333.1 Essential tremor Neurological 0.978 0.904 – 1.06 0.579 725 7163 all phecode
333.2 Myoclonus Neurological 1.18 0.998 – 1.39 0.0523 159 1590 all phecode
333.4 Torsion dystonia Neurological 0.868 0.775 – 0.971 0.0137 352 3504 all phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 0.965 0.773 – 1.21 0.757 89 890 all phecode
334 Degenerative disease of the spinal cord Neurological 1.02 0.955 – 1.09 0.566 1058 10562 all phecode
334.1 Spinocerebellar disease Neurological 0.951 0.75 – 1.21 0.678 79 790 all phecode
334.2 Anterior horn cell disease Neurological 0.962 0.785 – 1.18 0.711 110 1080 all phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 0.903 0.701 – 1.16 0.428 71 693 all phecode
335 Multiple sclerosis Neurological 1.07 0.958 – 1.19 0.239 396 3951 all phecode
337 Disorders of the autonomic nervous system Neurological 1 0.932 – 1.08 0.921 808 7413 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.07 0.961 – 1.19 0.215 370 3164 all phecode
338 Pain Neurological 1.07 1.05 – 1.09 7e-12 20346 26417 all phecode
338.1 Acute pain Neurological 1.05 1.03 – 1.08 3.07e-07 15582 26313 all phecode
338.2 Chronic pain Neurological 1.11 1.08 – 1.13 2.32e-17 10994 26368 all phecode
339 Other headache syndromes Neurological 1.03 1 – 1.05 0.021 9242 34658 all phecode
340 Migraine Neurological 1.02 0.995 – 1.05 0.116 6708 30587 all phecode
340.1 Migrain with aura Neurological 1.01 0.969 – 1.04 0.771 3624 23684 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.05 0.874 – 1.25 0.621 133 1330 all phecode
342 Hemiplegia Neurological 0.995 0.903 – 1.1 0.914 464 4607 all phecode
343 Infantile cerebral palsy Neurological 1.07 0.856 – 1.35 0.535 85 847 all phecode
344 Other paralytic syndromes Neurological 1.04 0.961 – 1.13 0.319 682 6808 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.01 0.968 – 1.05 0.673 2553 25307 all phecode
345.1 Epilepsy Neurological 0.985 0.912 – 1.06 0.692 747 7465 all phecode
345.11 Generalized convulsive epilepsy Neurological 0.972 0.851 – 1.11 0.68 233 2330 all phecode
345.12 Partial epilepsy Neurological 0.969 0.885 – 1.06 0.493 534 5335 all phecode
345.3 Convulsions Neurological 1 0.959 – 1.05 0.943 2396 23796 all phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.935 0.8 – 1.09 0.401 183 1824 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.945 0.894 – 0.999 0.0456 1472 14587 all phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.836 0.691 – 1.01 0.0671 120 1181 all phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 0.875 0.72 – 1.06 0.18 110 1100 all phecode
347 Cataplexy and narcolepsy Neurological 1.15 0.936 – 1.42 0.18 101 1010 all phecode
348 Other conditions of brain Neurological 1.03 0.979 – 1.08 0.268 1793 17894 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.01 0.942 – 1.08 0.779 905 9034 all phecode
348.4 Cerebral cysts Neurological 0.937 0.814 – 1.08 0.368 229 2290 all phecode
348.7 Coma Neurological 0.958 0.834 – 1.1 0.548 229 2275 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.07 0.997 – 1.15 0.0606 853 8479 all phecode
348.9 Other conditions of brain, NOS Neurological 0.961 0.919 – 1 0.0735 2341 23287 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.07 0.997 – 1.14 0.0615 941 9385 all phecode
350 Abnormal movement Neurological 1.02 0.993 – 1.05 0.155 6706 38762 all phecode
350.1 Abnormal involuntary movements Neurological 1.01 0.974 – 1.05 0.557 3273 30524 all phecode
350.2 Abnormality of gait Neurological 1.03 0.99 – 1.06 0.161 3920 30520 all phecode
350.3 Lack of coordination Neurological 0.943 0.884 – 1.01 0.0727 1062 10554 all phecode
350.5 Abnormal reflex Neurological 1 0.865 – 1.16 0.966 200 1988 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.97 0.887 – 1.06 0.506 558 5576 all phecode
351 Other peripheral nerve disorders Neurological 1.07 1.04 – 1.1 1.76e-07 7401 34460 all phecode
352 Disorders of other cranial nerves Neurological 0.996 0.947 – 1.05 0.892 1714 17106 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.95 0.867 – 1.04 0.27 535 5344 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.03 0.951 – 1.11 0.51 783 7826 all phecode
353 Nerve root and plexus disorders Neurological 1.06 1.02 – 1.09 0.00101 4256 33369 all phecode
353.1 Nerve plexus lesions Neurological 1.06 0.952 – 1.18 0.289 390 3900 all phecode
353.2 Nerve root lesions Neurological 0.961 0.797 – 1.16 0.677 130 1287 all phecode
355 Complex regional/central pain syndrome Neurological 1.03 0.937 – 1.13 0.557 531 5295 all phecode
355.1 Chronic pain syndrome Neurological 1.13 1.05 – 1.22 0.00101 843 8386 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.07 1.03 – 1.12 0.0018 2335 20731 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.09 1.05 – 1.13 4.86e-06 3472 29956 all phecode
358 Myoneural disorders Neurological 1.07 1 – 1.14 0.0398 1147 11391 all phecode
358.1 Myasthenia gravis Neurological 0.832 0.681 – 1.02 0.0698 109 1082 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.967 0.907 – 1.03 0.29 1134 11274 all phecode
359.1 Muscular dystrophies Neurological 1.09 0.833 – 1.43 0.521 64 632 all phecode
359.2 Myopathy Neurological 0.967 0.907 – 1.03 0.311 1092 10843 all phecode
360 Disorders of the globe Sense Organs 0.873 0.725 – 1.05 0.15 131 1276 all phecode
360.2 Progressive myopia Sense Organs 0.837 0.64 – 1.09 0.193 65 640 all phecode
361 Retinal detachments and defects Sense Organs 0.967 0.894 – 1.05 0.408 733 7131 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.9 0.795 – 1.02 0.0938 302 2962 all phecode
362 Other retinal disorders Sense Organs 0.999 0.962 – 1.04 0.957 3569 22997 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.972 0.927 – 1.02 0.238 2172 15483 all phecode
362.21 Macular degeneration, dry Sense Organs 0.89 0.8 – 0.991 0.0336 419 3438 all phecode
362.22 Macular degeneration, wet Sense Organs 0.988 0.827 – 1.18 0.897 148 1184 all phecode
362.23 Cystoid macular degeneration of retina Sense Organs 0.928 0.834 – 1.03 0.168 408 3839 all phecode
362.26 Macular puckering of retina Sense Organs 0.965 0.901 – 1.03 0.314 976 8610 all phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.917 0.833 – 1.01 0.0805 488 4558 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.977 0.928 – 1.03 0.36 1883 13955 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.05 0.982 – 1.13 0.147 976 8527 all phecode
362.31 Separation of retinal layers Sense Organs 0.973 0.878 – 1.08 0.602 413 4056 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.02 0.942 – 1.11 0.589 662 5933 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.942 0.846 – 1.05 0.272 392 3787 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.05 0.909 – 1.21 0.507 215 2103 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.15 1 – 1.32 0.0493 241 2368 all phecode
362.9 Retinal edema Sense Organs 1.13 1 – 1.27 0.0433 324 2936 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.973 0.884 – 1.07 0.574 492 4746 all phecode
363.3 Chorioretinal scars Sense Organs 0.927 0.826 – 1.04 0.193 332 3184 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.953 0.894 – 1.01 0.132 1132 10772 all phecode
364.1 Corneal opacity Sense Organs 0.988 0.888 – 1.1 0.832 394 3846 all phecode
364.2 Corneal edema Sense Organs 1.02 0.847 – 1.24 0.811 123 1208 all phecode
364.4 Corneal degenerations Sense Organs 0.96 0.864 – 1.07 0.443 402 3962 all phecode
364.41 Keratoconus Sense Organs 0.806 0.631 – 1.03 0.0831 75 739 all phecode
364.5 Corneal dystrophy Sense Organs 0.983 0.894 – 1.08 0.73 502 4682 all phecode
364.51 Fuchs' dystrophy Sense Organs 0.924 0.809 – 1.05 0.239 266 2521 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.841 0.671 – 1.05 0.132 91 885 all phecode
365 Glaucoma Sense Organs 0.96 0.92 – 1 0.0566 2672 21326 all phecode
365.1 Open-angle glaucoma Sense Organs 0.941 0.869 – 1.02 0.141 705 6491 all phecode
365.11 Primary open angle glaucoma Sense Organs 0.887 0.798 – 0.987 0.0278 403 3681 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.01 0.883 – 1.15 0.888 251 2370 all phecode
366 Cataract Sense Organs 0.985 0.959 – 1.01 0.262 8611 28043 all phecode
366.1 Nonsenile Cataract Sense Organs 0.894 0.769 – 1.04 0.145 207 1979 all phecode
366.2 Senile cataract Sense Organs 0.97 0.939 – 1 0.0568 5480 24980 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.974 0.95 – 0.998 0.0323 8967 37779 all phecode
367.1 Myopia Sense Organs 0.955 0.926 – 0.985 0.00363 5014 34677 all phecode
367.2 Astigmatism Sense Organs 0.947 0.915 – 0.979 0.00144 4161 32463 all phecode
367.8 Hypermetropia Sense Organs 0.959 0.915 – 1.01 0.0842 2039 18599 all phecode
367.9 Blindness and low vision Sense Organs 1.05 0.992 – 1.12 0.0892 1277 12356 all phecode
368 Visual disturbances Sense Organs 1 0.974 – 1.03 0.873 5715 39599 all phecode
368.1 Amblyopia Sense Organs 0.996 0.916 – 1.08 0.917 651 6479 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.984 0.923 – 1.05 0.619 1087 10786 all phecode
368.3 Anisometropia Sense Organs 0.893 0.775 – 1.03 0.117 219 2168 all phecode
368.4 Visual field defects Sense Organs 1.02 0.954 – 1.08 0.625 1132 11173 all phecode
368.9 Subjective visual disturbances Sense Organs 0.981 0.919 – 1.05 0.557 1070 10620 all phecode
368.91 Psychophysical visual disturbances Sense Organs 1.14 0.947 – 1.37 0.168 120 1171 all phecode
369 Infection of the eye Sense Organs 0.973 0.937 – 1.01 0.152 3185 28240 all phecode
369.2 Eye infection, viral Sense Organs 1.01 0.922 – 1.12 0.779 502 4954 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.966 0.927 – 1.01 0.1 2716 24970 all phecode
370 Keratitis Sense Organs 0.936 0.884 – 0.992 0.0247 1365 13169 all phecode
370.1 Corneal ulcer Sense Organs 0.964 0.838 – 1.11 0.61 223 2194 all phecode
370.2 Superficial keratitis Sense Organs 0.926 0.847 – 1.01 0.0951 546 5393 all phecode
370.3 Keratoconjunctivitis Sense Organs 0.972 0.893 – 1.06 0.503 649 6263 all phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.98 0.836 – 1.15 0.803 179 1677 all phecode
371 Inflammation of the eye Sense Organs 0.952 0.921 – 0.984 0.00335 4414 32310 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.972 0.889 – 1.06 0.542 541 5278 all phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.975 0.909 – 1.05 0.49 906 8939 all phecode
371.21 Allergic conjunctivitis Sense Organs 0.951 0.88 – 1.03 0.205 756 7515 all phecode
371.3 Inflammation of eyelids Sense Organs 0.947 0.913 – 0.983 0.00442 3398 26983 all phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 0.884 0.736 – 1.06 0.186 133 1291 all phecode
372 Disorders of conjunctiva Sense Organs 0.946 0.888 – 1.01 0.0843 1118 10728 all phecode
374 Other disorders of eyelids Sense Organs 0.96 0.922 – 0.999 0.0438 2940 24188 all phecode
374.1 Ectropion or entropion Sense Organs 0.901 0.814 – 0.998 0.0464 431 4084 all phecode
374.2 Lagophthalmos Sense Organs 1.05 0.912 – 1.2 0.523 235 2335 all phecode
374.3 Ptosis of eyelid Sense Organs 0.978 0.917 – 1.04 0.502 1102 10734 all phecode
374.6 Dermatochalasis Sense Organs 1.01 0.943 – 1.08 0.821 1040 9720 all phecode
375 Disorders of lacrimal system Sense Organs 0.961 0.927 – 0.997 0.0317 3694 26045 all phecode
375.1 Dry eyes Sense Organs 0.954 0.922 – 0.988 0.00898 4040 26751 all phecode
375.2 Epiphora Sense Organs 0.94 0.85 – 1.04 0.234 442 4354 all phecode
376 Disorders of the orbit Sense Organs 1.04 0.931 – 1.17 0.475 352 3508 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.02 0.956 – 1.1 0.494 913 9021 all phecode
377.1 Optic atrophy Sense Organs 0.991 0.872 – 1.12 0.883 283 2793 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.01 0.924 – 1.1 0.857 585 5775 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.957 0.902 – 1.01 0.141 1275 12460 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.953 0.885 – 1.03 0.195 828 8130 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.984 0.84 – 1.15 0.837 170 1686 all phecode
378.5 Paralytic strabismus Sense Organs 0.815 0.726 – 0.915 0.00055 349 3437 all phecode
379 Other disorders of eye Sense Organs 0.976 0.946 – 1.01 0.134 5046 29999 all phecode
379.1 Scleritis and episcleritis Sense Organs 0.96 0.819 – 1.12 0.611 176 1743 all phecode
379.2 Disorders of vitreous body Sense Organs 0.963 0.927 – 0.999 0.0443 3634 23186 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.875 0.728 – 1.05 0.154 135 1258 all phecode
379.4 Anomalies of pupillary function Sense Organs 0.942 0.831 – 1.07 0.352 287 2833 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.07 0.949 – 1.21 0.262 304 2948 all phecode
379.51 Pigmentary iris degeneration Sense Organs 0.848 0.663 – 1.09 0.19 77 731 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.988 0.928 – 1.05 0.714 1129 11130 all phecode
380 Disorders of external ear Sense Organs 0.91 0.87 – 0.952 4.42e-05 2242 20393 all phecode
380.1 Otitis externa Sense Organs 0.966 0.915 – 1.02 0.221 1469 14580 all phecode
380.4 Impacted cerumen Sense Organs 0.907 0.87 – 0.946 5.02e-06 2648 23557 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.01 0.978 – 1.04 0.55 4255 36417 all phecode
381.1 Otitis media Sense Organs 1.04 1.01 – 1.08 0.0265 3079 29813 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.05 1 – 1.09 0.0288 2610 25602 all phecode
381.2 Eustachian tube disorders Sense Organs 0.944 0.898 – 0.993 0.0255 1816 17827 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.18 0.996 – 1.4 0.0563 153 1530 all phecode
381.9 Otorrhea Sense Organs 1.1 0.985 – 1.23 0.0901 372 3713 all phecode
382 Otalgia Sense Organs 1.02 0.972 – 1.07 0.402 1884 18673 all phecode
383 Otosclerosis Sense Organs 0.957 0.792 – 1.16 0.65 124 1240 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.04 0.951 – 1.15 0.366 516 5156 all phecode
384.1 Myringitis Sense Organs 0.849 0.638 – 1.13 0.264 51 502 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.06 0.951 – 1.18 0.301 403 4029 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.966 0.873 – 1.07 0.496 432 4320 all phecode
385.3 Cholesteatoma Sense Organs 1.01 0.889 – 1.14 0.913 277 2770 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.884 0.733 – 1.07 0.198 118 1180 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.02 0.972 – 1.07 0.417 1882 18186 all phecode
386.1 Meniere's disease Sense Organs 1 0.888 – 1.13 0.979 319 3156 all phecode
386.2 Peripheral or central vertigo Sense Organs 1.01 0.959 – 1.07 0.661 1586 15423 all phecode
386.21 Central origin vertigo Sense Organs 1.04 0.976 – 1.1 0.236 1208 11844 all phecode
386.3 Labyrinthitis Sense Organs 1.05 0.99 – 1.11 0.109 1482 14530 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.01 0.985 – 1.04 0.4 6933 38286 all phecode
388 Other disorders of ear Sense Organs 0.991 0.926 – 1.06 0.787 960 9501 all phecode
389 Hearing loss Sense Organs 0.98 0.956 – 1.01 0.124 8182 38069 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.936 0.905 – 0.969 0.000149 4107 29258 all phecode
389.2 Conductive hearing loss Sense Organs 0.953 0.888 – 1.02 0.174 905 9042 all phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.967 0.829 – 1.13 0.673 192 1808 all phecode
389.4 Tinnitus Sense Organs 0.933 0.893 – 0.976 0.00231 2291 22130 all phecode
389.5 Disorders of acoustic nerve Sense Organs 1.03 0.851 – 1.23 0.793 124 1229 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.04 0.981 – 1.1 0.198 1458 13732 all phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 1.05 0.941 – 1.18 0.369 350 3415 all phecode
394.2 Mitral valve disease Circulatory System 1 0.909 – 1.1 0.975 462 4560 all phecode
394.3 Aortic valve disease Circulatory System 1.1 0.935 – 1.29 0.252 176 1691 all phecode
394.4 Acute rheumatic heart disease Circulatory System 1.07 0.805 – 1.44 0.625 55 546 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.08 0.989 – 1.18 0.0845 587 5739 all phecode
395 Heart valve disorders Circulatory System 1.02 0.988 – 1.06 0.208 3976 28748 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.951 0.909 – 0.996 0.0327 2175 20441 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.09 1.04 – 1.14 0.000577 2060 17194 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.03 0.934 – 1.13 0.583 493 4864 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.16 0.952 – 1.42 0.138 108 1080 all phecode
395.6 Heart valve replaced Circulatory System 1.09 1.02 – 1.16 0.00686 1177 10833 all phecode
396 Abnormal heart sounds Circulatory System 1.01 0.983 – 1.05 0.357 4718 34395 all phecode
401 Hypertension Circulatory System 1.27 1.24 – 1.3 7.86e-104 23317 23367 all phecode
401.1 Essential hypertension Circulatory System 1.27 1.24 – 1.3 3.51e-104 23158 23364 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.38 1.32 – 1.44 1.09e-51 3503 14616 all phecode
401.21 Hypertensive heart disease Circulatory System 1.32 1.22 – 1.42 5.18e-13 893 6607 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.37 1.3 – 1.43 1.64e-39 2584 13072 all phecode
401.3 Other hypertensive complications Circulatory System 1.27 1.22 – 1.33 2.36e-26 2679 15833 all phecode
411 Ischemic Heart Disease Circulatory System 1.16 1.13 – 1.19 1.12e-27 8807 30299 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.17 1.09 – 1.25 1.1e-05 937 8574 all phecode
411.2 Myocardial infarction Circulatory System 1.21 1.16 – 1.25 1.02e-22 3594 21716 all phecode
411.3 Angina pectoris Circulatory System 1.15 1.1 – 1.2 1.87e-10 2485 18304 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.16 1.13 – 1.19 6.41e-25 7555 27492 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.07 0.899 – 1.26 0.46 156 1529 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.16 1.13 – 1.2 5.3e-23 6331 25741 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.21 1.1 – 1.34 0.000219 442 4211 all phecode
414 Other forms of chronic heart disease Circulatory System 1.1 1.06 – 1.15 1.3e-06 3101 22616 all phecode
414.2 ASCVD Circulatory System 1.09 1.01 – 1.18 0.0369 718 6816 all phecode
415 Pulmonary heart disease Circulatory System 1.14 1.1 – 1.19 1.39e-12 3366 30208 all phecode
415.1 Acute pulmonary heart disease Circulatory System 1.11 1.06 – 1.17 1.62e-05 1912 19014 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.11 1.06 – 1.17 2.23e-05 1906 18953 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.17 1.12 – 1.23 3.81e-10 1808 17605 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.16 1.07 – 1.25 0.000367 706 7032 all phecode
416 Cardiomegaly Circulatory System 1.08 1.02 – 1.15 0.00791 1254 12372 all phecode
418 Nonspecific chest pain Circulatory System 1.04 1.02 – 1.07 8.26e-05 12650 33952 all phecode
418.1 Precordial pain Circulatory System 1.05 0.989 – 1.11 0.112 1471 13782 all phecode
420 Carditis Circulatory System 1.09 1.03 – 1.15 0.00256 1588 15680 all phecode
420.1 Myocarditis Circulatory System 1.03 0.835 – 1.27 0.775 97 958 all phecode
420.2 Pericarditis Circulatory System 1.04 0.971 – 1.12 0.243 842 8402 all phecode
420.21 Acute pericarditis Circulatory System 1.19 1.01 – 1.4 0.0322 177 1764 all phecode
420.22 Chronic pericarditis Circulatory System 1.11 0.916 – 1.34 0.289 117 1153 all phecode
420.3 Endocarditis Circulatory System 1.17 1.09 – 1.27 5.31e-05 764 7535 all phecode
425 Cardiomyopathy Circulatory System 1.11 1.06 – 1.16 1.96e-05 2078 19881 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.11 1.06 – 1.16 3.07e-05 1989 19025 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.04 0.906 – 1.2 0.552 208 2050 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.07 0.931 – 1.24 0.328 201 1992 all phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.07 0.948 – 1.2 0.285 317 3170 all phecode
425.8 Other cardiomyopathy Circulatory System 1.15 0.914 – 1.44 0.235 95 931 all phecode
426 Cardiac conduction disorders Circulatory System 1.06 1.04 – 1.09 1.1e-06 12327 25440 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.11 1.05 – 1.17 7.57e-05 1903 11501 all phecode
426.21 First degree AV block Circulatory System 1.07 1.01 – 1.14 0.0218 1313 8899 all phecode
426.22 Mobitz II AV block Circulatory System 0.92 0.701 – 1.21 0.551 64 553 all phecode
426.23 Second degree AV block Circulatory System 1.03 0.887 – 1.19 0.723 216 1925 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.11 1 – 1.23 0.046 461 3823 all phecode
426.25 Other heart block Circulatory System 0.979 0.847 – 1.13 0.78 203 1803 all phecode
426.3 Bundle branch block Circulatory System 1.08 1.03 – 1.13 0.00186 2306 13999 all phecode
426.31 Right bundle branch block Circulatory System 1.07 1.01 – 1.14 0.0145 1423 10758 all phecode
426.32 Left bundle branch block Circulatory System 1.12 1.04 – 1.2 0.00163 969 8110 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1 0.794 – 1.26 0.99 82 820 all phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.06 1.03 – 1.09 5.15e-06 10577 25186 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.06 0.976 – 1.15 0.168 679 6650 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.09 1.03 – 1.15 0.00195 1754 11536 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.09 1.02 – 1.16 0.00768 1171 8184 all phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.12 1.04 – 1.21 0.00253 846 7320 all phecode
427 Cardiac dysrhythmias Circulatory System 1.03 1.01 – 1.06 0.00113 17397 25735 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.02 0.976 – 1.06 0.391 2474 18178 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.01 0.955 – 1.06 0.794 1595 14293 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.05 0.988 – 1.12 0.116 1181 9915 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.09 1.05 – 1.12 1.27e-06 5313 18688 all phecode
427.21 Atrial fibrillation Circulatory System 1.09 1.05 – 1.12 1.96e-06 5188 18409 all phecode
427.22 Atrial flutter Circulatory System 1.06 1 – 1.12 0.0344 1693 11042 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.03 1.01 – 1.06 0.018 8688 25552 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.11 1.01 – 1.22 0.0231 536 5233 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.979 0.848 – 1.13 0.776 216 2118 all phecode
427.42 Cardiac arrest Circulatory System 1.2 1.08 – 1.34 0.000523 410 4034 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.02 0.993 – 1.05 0.134 6905 25457 all phecode
427.6 Premature beats Circulatory System 0.998 0.954 – 1.04 0.919 2359 16248 all phecode
427.61 Supraventricular premature beats Circulatory System 1.07 0.982 – 1.16 0.127 670 6287 all phecode
427.7 Tachycardia NOS Circulatory System 1.07 1.04 – 1.11 9.15e-06 5124 25531 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.06 0.985 – 1.14 0.125 912 7501 all phecode
427.9 Palpitations Circulatory System 0.973 0.941 – 1.01 0.105 4430 24505 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.19 1.15 – 1.24 9.66e-24 4300 23663 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.21 1.16 – 1.25 4.73e-24 3756 22446 all phecode
428.2 Heart failure NOS Circulatory System 1.22 1.17 – 1.26 2.31e-25 3701 21722 all phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.21 1.15 – 1.27 1e-12 1765 14476 all phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.25 1.18 – 1.32 6.77e-16 1648 13395 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.05 1.03 – 1.08 3.45e-06 12635 32504 all phecode
429.1 Heart transplant/surgery Circulatory System 1.09 1.02 – 1.15 0.00723 1219 11696 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.09 1.06 – 1.12 1.86e-08 6322 29232 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.04 1.01 – 1.06 0.00159 9650 32421 all phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.1 1.01 – 1.18 0.0222 723 7072 all phecode
430 Intracranial hemorrhage Circulatory System 0.916 0.849 – 0.988 0.023 789 7842 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.935 0.82 – 1.07 0.31 261 2610 all phecode
430.2 Intracerebral hemorrhage Circulatory System 0.92 0.824 – 1.03 0.142 368 3671 all phecode
430.3 Subdural hemorrhage Circulatory System 0.821 0.722 – 0.933 0.00263 272 2680 all phecode
433 Cerebrovascular disease Circulatory System 1.05 1.02 – 1.08 0.0034 5463 32242 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.06 1.01 – 1.11 0.019 1978 16212 all phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.14 1 – 1.31 0.0485 260 2517 all phecode
433.12 Cerebral atherosclerosis Circulatory System 0.957 0.764 – 1.2 0.704 80 789 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.05 1.01 – 1.1 0.0205 2437 21732 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.05 1.01 – 1.1 0.018 2357 21103 all phecode
433.3 Cerebral ischemia Circulatory System 1.01 0.971 – 1.05 0.578 2780 22868 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.03 0.989 – 1.08 0.14 2409 20762 all phecode
433.5 Cerebral aneurysm Circulatory System 0.962 0.872 – 1.06 0.439 474 4724 all phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.03 0.935 – 1.14 0.538 464 4518 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.08 0.999 – 1.17 0.0542 695 6822 all phecode
440 Atherosclerosis Circulatory System 1.13 1.08 – 1.18 2.21e-08 2477 19724 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.02 0.886 – 1.17 0.795 231 2291 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.12 1.06 – 1.19 3.51e-05 1516 13532 all phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.22 1.07 – 1.38 0.00254 274 2669 all phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.09 1.02 – 1.17 0.00966 1040 9647 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.14 1.06 – 1.23 0.00042 846 8124 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.06 0.965 – 1.16 0.229 515 5115 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.11 0.972 – 1.27 0.12 240 2387 all phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.06 0.895 – 1.25 0.522 154 1536 all phecode
442 Other aneurysm Circulatory System 1.11 1.06 – 1.15 1.69e-06 2779 21466 all phecode
442.1 Aortic aneurysm Circulatory System 1.12 1.07 – 1.18 1.35e-06 2054 16492 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.13 1.06 – 1.2 0.000197 1189 10558 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.1 0.95 – 1.28 0.201 202 2002 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.03 0.88 – 1.2 0.727 179 1765 all phecode
442.4 Arterial dissection Circulatory System 0.942 0.809 – 1.1 0.436 184 1840 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.05 0.945 – 1.17 0.351 399 3978 all phecode
443 Peripheral vascular disease Circulatory System 1.08 1.04 – 1.12 0.000119 3086 24814 all phecode
443.1 Raynaud's syndrome Circulatory System 0.898 0.831 – 0.971 0.0068 742 7390 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.36 1.18 – 1.57 3.35e-05 220 2087 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.07 1.03 – 1.12 0.000918 2557 21985 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.12 1.08 – 1.18 2.62e-07 2341 18862 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.05 0.978 – 1.13 0.177 848 8423 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.947 0.839 – 1.07 0.376 313 3099 all phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 0.949 0.801 – 1.12 0.544 155 1548 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.01 0.917 – 1.12 0.826 460 4559 all phecode
446.4 Wegener's granulomatosis Circulatory System 0.954 0.779 – 1.17 0.652 109 1075 all phecode
446.5 Giant cell arteritis Circulatory System 0.818 0.649 – 1.03 0.0893 79 749 all phecode
446.9 Arteritis NOS Circulatory System 1.03 0.911 – 1.16 0.638 289 2876 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.07 1.02 – 1.11 0.00299 2647 22765 all phecode
447.1 Stricture of artery Circulatory System 1.12 1.02 – 1.23 0.0139 523 5163 all phecode
447.7 Aortic ectasia Circulatory System 1.07 0.996 – 1.16 0.0641 804 7938 all phecode
448 Disease of capillaries Circulatory System 0.913 0.859 – 0.97 0.00325 1237 12127 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.06 1.01 – 1.11 0.0186 2104 20985 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.07 0.988 – 1.15 0.0962 738 7355 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.06 0.931 – 1.21 0.37 244 2437 all phecode
452 Other venous embolism and thrombosis Circulatory System 1.11 1.08 – 1.15 4.46e-11 4957 29867 all phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1.15 1.02 – 1.31 0.0279 276 2747 all phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1.11 1.07 – 1.15 9.62e-08 3260 26940 all phecode
452.8 Postphlebitic syndrome Circulatory System 1.18 0.996 – 1.39 0.056 154 1529 all phecode
453 Chronic venous hypertension Circulatory System 1.23 1.07 – 1.42 0.00388 220 2168 all phecode
454 Varicose veins Circulatory System 1.06 1.02 – 1.1 0.00591 2827 24555 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1.07 1.03 – 1.12 0.00159 2469 21426 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.08 1.02 – 1.14 0.00601 1565 15056 all phecode
455 Hemorrhoids Circulatory System 0.961 0.933 – 0.99 0.00778 5799 29818 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.1 1.06 – 1.15 4.49e-07 3097 24898 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.1 1.05 – 1.15 7.73e-05 2095 15309 all phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.11 0.991 – 1.24 0.0723 324 3221 all phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.1 1.05 – 1.15 0.000145 1973 14689 all phecode
458 Hypotension Circulatory System 1.11 1.08 – 1.14 3.53e-11 5091 32185 all phecode
458.1 Orthostatic hypotension Circulatory System 1.06 1 – 1.12 0.0491 1344 12938 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.14 1.07 – 1.21 7.64e-05 1109 11012 all phecode
458.9 Hypotension NOS Circulatory System 1.11 1.07 – 1.14 7.42e-10 4618 31186 all phecode
459 Other disorders of circulatory system Circulatory System 1.09 1.06 – 1.11 3.63e-10 7825 34792 all phecode
459.1 Hemorrhage NOS Circulatory System 1.04 0.964 – 1.12 0.326 834 8215 all phecode
459.7 Blood vessel replaced Circulatory System 1.12 1.05 – 1.19 0.000216 1305 13023 all phecode
459.9 Circulatory disease NEC Circulatory System 1.09 1.06 – 1.12 1.18e-09 6706 33592 all phecode
464 Acute sinusitis Respiratory 0.981 0.951 – 1.01 0.24 4792 32137 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.979 0.956 – 1 0.0755 9601 35915 all phecode
465.2 Acute pharyngitis Respiratory 0.966 0.938 – 0.996 0.0272 5310 32365 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.998 0.901 – 1.11 0.977 443 4428 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.926 0.881 – 0.973 0.0024 1797 17640 all phecode
471 Nasal polyps Respiratory 0.952 0.873 – 1.04 0.273 592 5881 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.943 0.897 – 0.992 0.0225 1797 16986 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1 0.963 – 1.04 0.958 2983 25244 all phecode
473.1 Chronic laryngitis Respiratory 1.12 0.878 – 1.44 0.351 68 674 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.03 0.944 – 1.12 0.521 628 6254 all phecode
473.4 Voice disturbance Respiratory 0.994 0.951 – 1.04 0.798 2336 21975 all phecode
474 Acute and chronic tonsillitis Respiratory 0.996 0.928 – 1.07 0.919 880 7892 all phecode
474.1 Acute tonsillitis Respiratory 0.906 0.81 – 1.01 0.0886 335 3181 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.01 0.937 – 1.1 0.72 700 6445 all phecode
475 Chronic sinusitis Respiratory 0.953 0.922 – 0.985 0.00389 4378 27891 all phecode
475.9 Postnasal drip Respiratory 0.883 0.823 – 0.947 0.000509 922 9017 all phecode
476 Allergic rhinitis Respiratory 0.984 0.963 – 1.01 0.141 12687 28117 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.03 0.971 – 1.1 0.303 1150 11318 all phecode
478 Throat pain Respiratory 0.944 0.852 – 1.05 0.266 426 4195 all phecode
479 Other upper respiratory disease Respiratory 1.02 0.986 – 1.05 0.318 5627 28048 all phecode
480 Pneumonia Respiratory 1.08 1.05 – 1.11 4.55e-08 5947 37034 all phecode
480.1 Bacterial pneumonia Respiratory 1.06 0.997 – 1.13 0.0604 1155 11495 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.11 1.01 – 1.21 0.0241 568 5644 all phecode
480.12 Pseudomonal pneumonia Respiratory 0.932 0.783 – 1.11 0.426 153 1523 all phecode
480.13 MRSA pneumonia Respiratory 1.05 0.864 – 1.27 0.644 117 1165 all phecode
480.2 Viral pneumonia Respiratory 1.11 0.961 – 1.29 0.154 202 1992 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.1 0.93 – 1.29 0.271 159 1590 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.05 0.877 – 1.26 0.585 135 1312 all phecode
481 Influenza Respiratory 1.04 0.982 – 1.1 0.183 1355 13284 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.04 1.01 – 1.08 0.0225 3412 29871 all phecode
495 Asthma Respiratory 1.1 1.07 – 1.13 6.81e-14 8671 33569 all phecode
495.1 Chronic obstructive asthma Respiratory 1.19 1.07 – 1.33 0.00118 397 3925 all phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 1.14 0.892 – 1.44 0.303 81 802 all phecode
495.2 Asthma with exacerbation Respiratory 1.02 0.971 – 1.08 0.387 1629 16033 all phecode
496 Chronic airway obstruction Respiratory 1.19 1.15 – 1.22 2.02e-27 5343 28343 all phecode
496.1 Emphysema Respiratory 1.16 1.1 – 1.21 6.34e-10 2134 19414 all phecode
496.2 Chronic bronchitis Respiratory 1.22 1.18 – 1.27 1.75e-30 4128 26624 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.23 1.19 – 1.28 1.79e-30 3747 25467 all phecode
496.3 Bronchiectasis Respiratory 1.01 0.919 – 1.1 0.898 549 5453 all phecode
497 Bronchitis Respiratory 1.07 1.02 – 1.12 0.00848 1946 18824 all phecode
498 Acute bronchospasm Respiratory 1.28 1.16 – 1.41 5.13e-07 496 4943 all phecode
499 Cystic fibrosis Respiratory 1 0.847 – 1.18 0.985 151 1510 all phecode
500 Lung disease due to external agents Respiratory 1.06 0.974 – 1.16 0.168 557 5551 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.02 0.812 – 1.27 0.879 92 920 all phecode
500.2 Pneumoconiosis Respiratory 1.11 0.879 – 1.4 0.378 78 764 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.08 0.996 – 1.18 0.0627 634 6225 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.06 0.982 – 1.14 0.136 815 8076 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.19 1.1 – 1.28 4.83e-06 835 8243 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.08 0.992 – 1.18 0.0762 595 5878 all phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 1.06 0.942 – 1.2 0.323 311 3084 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.16 1.1 – 1.22 4.9e-08 1638 15749 all phecode
506 Empyema and pneumothorax Respiratory 1.08 1.04 – 1.13 9.79e-05 2894 25235 all phecode
507 Pleurisy; pleural effusion Respiratory 1.1 1.06 – 1.15 6.74e-07 2916 26208 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.12 1.07 – 1.17 3.27e-07 2382 22588 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.12 1.09 – 1.16 2.59e-11 4032 29477 all phecode
509.1 Respiratory failure Respiratory 1.14 1.09 – 1.2 9.09e-08 1937 18949 all phecode
509.2 Respiratory insufficiency Respiratory 1.13 1.06 – 1.2 0.000185 1174 11679 all phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.09 1.04 – 1.15 0.000976 1689 16489 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.18 1.12 – 1.24 1.57e-10 1741 17249 all phecode
510 Other diseases of lung Respiratory 1.04 1.01 – 1.07 0.0178 5503 35907 all phecode
510.2 Lung transplant Respiratory 1.05 0.896 – 1.23 0.537 176 1757 all phecode
512 Other symptoms of respiratory system Respiratory 1.08 1.06 – 1.1 8.52e-14 18621 28154 all phecode
512.1 Wheezing Respiratory 1.19 1.13 – 1.26 7.7e-10 1409 13516 all phecode
512.2 Painful respiration Respiratory 1.04 0.996 – 1.09 0.0737 2309 21263 all phecode
512.3 Abnormal chest sounds Respiratory 1.06 0.935 – 1.2 0.374 291 2845 all phecode
512.7 Shortness of breath Respiratory 1.12 1.09 – 1.15 8.31e-20 10034 28081 all phecode
512.8 Cough Respiratory 1.06 1.03 – 1.09 4.02e-06 9501 28148 all phecode
512.9 Other dyspnea Respiratory 1.1 1.08 – 1.13 6.23e-17 10804 28104 all phecode
513 Respiratory abnormalities Respiratory 1.11 1.09 – 1.13 7.6e-22 12932 33822 all phecode
513.3 Hypoventilation Respiratory 1.19 1.11 – 1.28 1.08e-06 880 8646 all phecode
513.31 Apnea Respiratory 1.09 0.99 – 1.21 0.0776 462 4607 all phecode
513.32 Orthopnea Respiratory 1.12 0.974 – 1.29 0.113 220 2160 all phecode
513.4 Hyperventilation Respiratory 1.19 1.08 – 1.31 0.000295 515 5124 all phecode
513.8 Disorders of diaphragm Respiratory 1.06 0.929 – 1.21 0.389 258 2557 all phecode
514 Abnormal findings examination of lungs Respiratory 1.05 1.02 – 1.08 0.00113 5365 34834 all phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 0.96 0.843 – 1.09 0.541 258 2580 all phecode
514.2 Solitary pulmonary nodule Respiratory 1.05 1.01 – 1.09 0.00977 3018 27338 all phecode
516 Abnormal sputum Respiratory 1.09 1.01 – 1.18 0.0324 735 7332 all phecode
516.1 Hemoptysis Respiratory 1.09 1 – 1.19 0.0427 611 6080 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.06 1.03 – 1.09 5.95e-05 6458 39057 all phecode
519.1 Tracheostomy complications Respiratory 1.12 0.972 – 1.29 0.119 214 2136 all phecode
519.2 Respiratory complications Respiratory 1.07 0.967 – 1.18 0.195 445 4430 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.02 0.967 – 1.07 0.488 1588 15787 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.06 1.03 – 1.09 0.000279 4706 34489 all phecode
520 Disorders of tooth development Digestive 1.09 0.979 – 1.22 0.113 369 3690 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.32 1.12 – 1.56 0.00117 165 1642 all phecode
520.2 Disturbances in tooth eruption Digestive 0.981 0.855 – 1.13 0.788 218 2172 all phecode
521 Diseases of hard tissues of teeth Digestive 1.18 1.1 – 1.26 4.95e-06 898 8954 all phecode
521.1 Dental caries Digestive 1.19 1.1 – 1.27 4.18e-06 837 8349 all phecode
521.2 Dental abrasion, erosion and attrition Digestive 1.13 0.852 – 1.49 0.406 52 510 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.15 1.05 – 1.26 0.00191 535 5340 all phecode
522.5 Periapical abscess Digestive 1.18 1.07 – 1.31 0.000825 459 4583 all phecode
523 Gingival and periodontal diseases Digestive 1.15 1.06 – 1.24 0.000472 718 7180 all phecode
523.1 Gingivitis Digestive 1.05 0.89 – 1.25 0.544 142 1418 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.2 1.08 – 1.34 0.000968 364 3636 all phecode
523.31 Acute periodontitis Digestive 1.17 1.04 – 1.31 0.00987 311 3109 all phecode
523.32 Chronic periodontitis Digestive 1.28 1.06 – 1.55 0.00991 122 1204 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.904 0.808 – 1.01 0.0769 363 3630 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.913 0.794 – 1.05 0.202 220 2200 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.16 1.08 – 1.23 1.46e-05 1039 10382 all phecode
525.1 Loss of teeth or edentulism Digestive 1.17 1.05 – 1.3 0.00587 374 3731 all phecode
526 Diseases of the jaws Digestive 0.956 0.918 – 0.996 0.0308 2680 26455 all phecode
526.1 Cysts of the jaws Digestive 0.935 0.818 – 1.07 0.323 247 2470 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.844 0.737 – 0.967 0.0147 241 2383 all phecode
526.4 Temporomandibular joint disorders Digestive 0.95 0.9 – 1 0.0687 1504 15025 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.963 0.906 – 1.02 0.235 1187 11858 all phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 0.926 0.856 – 1 0.0527 741 7400 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.972 0.86 – 1.1 0.656 287 2864 all phecode
526.8 Exostosis of jaw Digestive 1.05 0.786 – 1.41 0.728 53 521 all phecode
526.9 Jaw disease NOS Digestive 0.96 0.871 – 1.06 0.402 487 4867 all phecode
527 Diseases of the salivary glands Digestive 1.01 0.959 – 1.06 0.759 1781 17771 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.05 0.803 – 1.38 0.704 58 579 all phecode
527.2 Sialoadenitis Digestive 1.08 0.968 – 1.2 0.175 394 3936 all phecode
527.7 Disturbance of salivary secretion Digestive 0.983 0.918 – 1.05 0.619 952 9481 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.07 0.937 – 1.22 0.316 254 2540 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.977 0.937 – 1.02 0.265 2643 26197 all phecode
528.1 Stomatitis and mucositis Digestive 0.955 0.88 – 1.04 0.262 668 6657 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.09 0.943 – 1.26 0.243 211 2110 all phecode
528.12 Oral aphthae Digestive 0.977 0.849 – 1.12 0.743 215 2137 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.08 0.939 – 1.23 0.295 235 2338 all phecode
528.4 Cysts of oral soft tissues Digestive 0.821 0.682 – 0.989 0.0379 124 1229 all phecode
528.41 Cyst of the salivary gland Digestive 0.885 0.699 – 1.12 0.306 77 760 all phecode
528.5 Diseases of lips Digestive 0.958 0.869 – 1.06 0.392 462 4602 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.05 0.878 – 1.25 0.603 137 1370 all phecode
528.7 Sialolithiasis Digestive 0.973 0.824 – 1.15 0.744 163 1623 all phecode
529 Diseases and other conditions of the tongue Digestive 1.05 0.968 – 1.14 0.241 690 6878 all phecode
529.1 Glossitis Digestive 0.946 0.784 – 1.14 0.565 129 1281 all phecode
529.6 Glossodynia Digestive 1.16 0.992 – 1.36 0.0619 168 1652 all phecode
530 Diseases of esophagus Digestive 1.1 1.08 – 1.12 6.71e-20 17081 27931 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.1 1.08 – 1.12 9.13e-20 16572 27931 all phecode
530.11 GERD Digestive 1.1 1.08 – 1.12 7.56e-20 16143 27929 all phecode
530.12 Ulcer of esophagus Digestive 1.1 0.993 – 1.23 0.0669 400 3983 all phecode
530.13 Barrett's esophagus Digestive 1.13 1.05 – 1.23 0.00126 762 7584 all phecode
530.14 Reflux esophagitis Digestive 1.08 1.03 – 1.14 0.00116 1900 17495 all phecode
530.15 Eosinophilic esophagitis Digestive 1.08 0.935 – 1.24 0.302 221 2210 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.1 1.01 – 1.19 0.0223 651 6473 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.04 0.965 – 1.11 0.336 911 8971 all phecode
530.5 Disorders of esophageal motility Digestive 1.08 0.987 – 1.18 0.0925 548 5432 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.914 0.76 – 1.1 0.338 129 1265 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.01 0.803 – 1.26 0.952 82 812 all phecode
530.9 Heartburn Digestive 1.08 1.02 – 1.14 0.00524 1519 14928 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.08 1.03 – 1.13 0.00103 2073 20617 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.08 0.966 – 1.2 0.181 391 3883 all phecode
531.2 Gastric ulcer Digestive 1.11 1.05 – 1.18 0.000525 1201 11970 all phecode
531.3 Duodenal ulcer Digestive 1.04 0.945 – 1.15 0.394 467 4640 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.05 0.974 – 1.13 0.199 804 8018 all phecode
531.5 Gastrojejunal ulcer Digestive 1.12 0.946 – 1.33 0.187 150 1500 all phecode
532 Dysphagia Digestive 1.09 1.06 – 1.13 1.07e-08 5585 26852 all phecode
535 Gastritis and duodenitis Digestive 1.07 1.02 – 1.11 0.00162 2799 27335 all phecode
535.1 Acute gastritis Digestive 1.11 1.05 – 1.18 0.000675 1178 11750 all phecode
535.2 Atrophic gastritis Digestive 1.04 0.929 – 1.17 0.489 344 3413 all phecode
535.6 Duodenitis Digestive 1.06 0.95 – 1.19 0.284 334 3337 all phecode
535.8 Other specified gastritis Digestive 1.03 0.947 – 1.12 0.504 638 6354 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.02 0.964 – 1.09 0.44 1255 12511 all phecode
536 Disorders of function of stomach Digestive 1.03 0.988 – 1.07 0.173 2911 27685 all phecode
536.3 Gastroparesis Digestive 1.08 0.998 – 1.17 0.0556 706 6901 all phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.03 0.932 – 1.15 0.525 407 4059 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.02 0.971 – 1.06 0.473 2150 21094 all phecode
537 Other disorders of stomach and duodenum Digestive 1.08 1.04 – 1.12 5.06e-05 3183 30048 all phecode
537.1 Lesions of stomach and duodenum Digestive 1.1 0.94 – 1.29 0.237 173 1725 all phecode
539 Bariatric surgery Digestive 1.65 1.56 – 1.75 4.06e-70 1509 15074 all phecode
540 Appendiceal conditions Digestive 0.917 0.833 – 1.01 0.0768 495 4948 all phecode
540.1 Appendicitis Digestive 0.893 0.803 – 0.992 0.0343 425 4239 all phecode
540.11 Acute appendicitis Digestive 0.882 0.786 – 0.989 0.0323 353 3511 all phecode
550 Abdominal hernia Digestive 1.07 1.04 – 1.09 4.05e-06 6768 37731 all phecode
550.1 Inguinal hernia Digestive 0.853 0.811 – 0.898 8.32e-10 1744 16488 all phecode
550.2 Diaphragmatic hernia Digestive 1.08 1.03 – 1.12 0.00033 2817 25849 all phecode
550.3 Femoral hernia Digestive 0.808 0.671 – 0.972 0.024 131 1291 all phecode
550.4 Umbilical hernia Digestive 1.1 1.03 – 1.16 0.0021 1313 13110 all phecode
550.5 Ventral hernia Digestive 1.18 1.13 – 1.23 1.09e-12 2241 22163 all phecode
550.6 Incisional hernia Digestive 1.22 1.15 – 1.29 2.06e-11 1313 13111 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.03 0.978 – 1.09 0.248 1536 15153 all phecode
555.1 Regional enteritis Digestive 1.07 0.998 – 1.15 0.0555 919 9095 all phecode
555.2 Ulcerative colitis Digestive 0.959 0.895 – 1.03 0.234 937 9315 all phecode
555.21 Ulcerative colitis (chronic) Digestive 0.904 0.825 – 0.992 0.0331 537 5315 all phecode
556 Ulceration of the lower GI tract Digestive 1.07 0.983 – 1.16 0.117 632 6267 all phecode
556.1 Ulceration of intestine Digestive 1.05 0.964 – 1.15 0.248 551 5451 all phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 1.05 0.906 – 1.21 0.542 214 2093 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.19 1.13 – 1.25 6.74e-11 1716 16490 all phecode
557.1 Celiac disease Digestive 0.953 0.86 – 1.06 0.358 421 4026 all phecode
558 Noninfectious gastroenteritis Digestive 1.05 1.01 – 1.09 0.013 3458 26408 all phecode
559 Ileostomy status Digestive 1.06 0.986 – 1.13 0.118 957 9565 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.06 1.02 – 1.1 0.00291 3004 24851 all phecode
560.1 Paralytic ileus Digestive 1.05 0.999 – 1.11 0.0549 1627 15714 all phecode
560.2 Impaction of intestine Digestive 1.05 0.945 – 1.18 0.343 387 3779 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.01 0.885 – 1.14 0.921 266 2647 all phecode
560.4 Other intestinal obstruction Digestive 1.06 1.01 – 1.12 0.0219 1651 16170 all phecode
561 Symptoms involving digestive system Digestive 1.01 0.966 – 1.05 0.714 2608 21766 all phecode
562 Diverticulosis and diverticulitis Digestive 1.03 1 – 1.07 0.0257 6295 23431 all phecode
562.1 Diverticulosis Digestive 1.03 1 – 1.06 0.0293 6246 23383 all phecode
562.2 Diverticulitis Digestive 1.06 1 – 1.12 0.0348 1611 15162 all phecode
564 Functional digestive disorders Digestive 1.06 1.03 – 1.08 3.15e-06 11411 28676 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.03 0.996 – 1.07 0.0761 3457 22266 all phecode
564.9 Personal history of diseases of digestive system Digestive 1.09 1.05 – 1.13 1.35e-05 3074 25861 all phecode
565 Anal and rectal conditions Digestive 0.994 0.958 – 1.03 0.729 3355 30757 all phecode
565.1 Anal and rectal polyp Digestive 1.02 0.961 – 1.08 0.515 1305 12649 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.14 1.08 – 1.21 4.27e-06 1364 13616 all phecode
568 Other disorders of peritoneum Digestive 1.15 1.09 – 1.21 2e-07 1705 17038 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.18 1.11 – 1.25 9.84e-08 1247 12468 all phecode
569 Other disorders of intestine Digestive 1.05 1.02 – 1.08 0.000126 8079 35231 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.01 0.901 – 1.14 0.838 326 3260 all phecode
569.2 Gastrointestinal complications Digestive 1.16 1.09 – 1.22 5.11e-07 1395 13933 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.11 1.07 – 1.14 5.46e-10 4610 32562 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.1 1.07 – 1.14 2.64e-09 4342 32234 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.14 1.07 – 1.22 8.68e-05 1018 10095 all phecode
571.6 Primary biliary cirrhosis Digestive 0.931 0.797 – 1.09 0.364 179 1790 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.13 1.05 – 1.21 0.000649 950 9498 all phecode
571.81 Portal hypertension Digestive 1.1 1.01 – 1.2 0.0331 573 5730 all phecode
572 Ascites (non malignant) Digestive 1.07 1.03 – 1.12 0.00149 2278 22675 all phecode
573 Other disorders of liver Digestive 1.07 1.04 – 1.11 2.01e-06 5599 33620 all phecode
573.1 Chronic passive congestion of liver Digestive 1.13 0.95 – 1.35 0.165 136 1359 all phecode
573.2 Liver replaced by transplant Digestive 1.07 0.944 – 1.2 0.305 292 2920 all phecode
573.3 Hepatomegaly Digestive 1.19 1.08 – 1.31 0.000368 470 4700 all phecode
573.4 Acute and subacute necrosis of liver Digestive 1.02 0.91 – 1.15 0.693 316 3149 all phecode
573.5 Jaundice (not of newborn) Digestive 1.01 0.944 – 1.08 0.752 958 9496 all phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.03 0.988 – 1.07 0.172 2756 26470 all phecode
573.7 Abnormal results of function study of liver Digestive 1.04 1 – 1.08 0.0329 3018 27774 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.03 1 – 1.07 0.0322 4679 33866 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.09 1.05 – 1.13 1.6e-05 3177 30809 all phecode
574.1 Cholelithiasis Digestive 1.09 1.05 – 1.14 8.03e-06 2924 28874 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.12 1 – 1.26 0.0468 342 3412 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.03 0.941 – 1.13 0.53 553 5501 all phecode
574.2 Calculus of bile duct Digestive 0.996 0.925 – 1.07 0.909 852 8503 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.08 1 – 1.16 0.041 822 8181 all phecode
575 Other biliary tract disease Digestive 1.04 0.991 – 1.08 0.121 2266 22555 all phecode
575.1 Cholangitis Digestive 0.986 0.882 – 1.1 0.804 354 3530 all phecode
575.2 Obstruction of bile duct Digestive 1.06 0.969 – 1.15 0.213 621 6201 all phecode
575.6 Cholesterolosis of gallbladder Digestive 1.03 0.896 – 1.19 0.65 207 2063 all phecode
575.7 Other disorders of gallbladder Digestive 0.979 0.914 – 1.05 0.543 939 9382 all phecode
575.8 Other disorders of biliary tract Digestive 1.07 1 – 1.14 0.0439 1154 11523 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.05 0.92 – 1.2 0.473 260 2600 all phecode
577 Diseases of pancreas Digestive 1.04 0.998 – 1.09 0.0635 2225 22106 all phecode
577.1 Acute pancreatitis Digestive 1.07 1 – 1.13 0.0352 1212 12110 all phecode
577.2 Chronic pancreatitis Digestive 1.17 1.06 – 1.29 0.00117 495 4950 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.07 0.974 – 1.17 0.163 570 5601 all phecode
578 Gastrointestinal hemorrhage Digestive 1.02 0.985 – 1.05 0.311 4554 37045 all phecode
578.1 Hematemesis Digestive 1.09 0.994 – 1.2 0.0669 485 4842 all phecode
578.2 Blood in stool Digestive 1.03 0.993 – 1.08 0.102 2743 26554 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.02 0.974 – 1.07 0.426 2210 21750 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.05 0.991 – 1.1 0.103 1562 15345 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.08 1.04 – 1.11 5.63e-06 4431 34209 all phecode
579.2 Splenomegaly Digestive 1.17 1.08 – 1.27 8.66e-05 730 7262 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.02 0.965 – 1.08 0.474 1410 13877 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.21 1.15 – 1.27 5.51e-14 1881 15516 all phecode
580.1 Glomerulonephritis Genitourinary 1.31 1.18 – 1.46 7.39e-07 401 3992 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.28 1.07 – 1.52 0.00637 146 1440 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.64 1.34 – 2.02 2.68e-06 114 1128 all phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.03 0.791 – 1.34 0.826 61 600 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.4 1.23 – 1.59 3.9e-07 277 2760 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.33 1.16 – 1.53 5e-05 221 2193 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.21 1.14 – 1.28 6.5e-11 1502 11930 all phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.26 1.18 – 1.35 1.14e-10 992 7228 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.15 1.06 – 1.25 0.000493 683 6612 all phecode
580.4 Renal sclerosis, NOS Genitourinary 1.33 1.19 – 1.5 1.29e-06 340 3400 all phecode
585 Renal failure Genitourinary 1.18 1.15 – 1.21 9.22e-33 7470 32340 all phecode
585.1 Acute renal failure Genitourinary 1.19 1.15 – 1.23 1.42e-23 4265 27230 all phecode
585.2 Renal failure NOS Genitourinary 1.18 1.1 – 1.27 1.24e-05 832 8162 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.19 1.16 – 1.23 4.72e-30 5580 29470 all phecode
585.31 Renal dialysis Genitourinary 1.26 1.16 – 1.36 9.42e-09 747 7423 all phecode
585.32 End stage renal disease Genitourinary 1.27 1.19 – 1.36 3.22e-12 1007 9783 all phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.2 1.15 – 1.25 2.3e-19 3209 21312 all phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.24 1.16 – 1.33 5.54e-10 977 9190 all phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.2 1.13 – 1.28 3.25e-09 1227 11191 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.11 1.08 – 1.14 4.17e-14 7628 34189 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.21 1.08 – 1.35 0.000985 349 3480 all phecode
586.11 Small kidney Genitourinary 1.27 1.1 – 1.47 0.00137 210 2093 all phecode
586.12 Vesicoureteral reflux Genitourinary 1.15 0.961 – 1.37 0.129 136 1360 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.05 0.991 – 1.11 0.0991 1381 12912 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.18 1.01 – 1.37 0.0358 187 1862 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.04 0.99 – 1.09 0.116 1821 17115 all phecode
587 Kidney replaced by transpant Genitourinary 1.17 1.09 – 1.26 2.63e-05 819 8134 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.26 1.17 – 1.34 8.16e-11 976 9389 all phecode
588.1 Renal osteodystrophy Genitourinary 1.16 1.02 – 1.32 0.0214 290 2900 all phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.26 1.16 – 1.36 8.99e-09 755 7275 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.17 1.09 – 1.25 6.18e-06 1007 9834 all phecode
590 Pyelonephritis Genitourinary 1.14 1.08 – 1.2 4.86e-06 1461 14350 all phecode
591 Urinary tract infection Genitourinary 1.03 1.01 – 1.05 0.0155 9873 32513 all phecode
592 Cystitis and urethritis Genitourinary 1.02 0.981 – 1.06 0.313 3038 24207 all phecode
592.1 Cystitis Genitourinary 1.02 0.983 – 1.07 0.257 2880 23279 all phecode
592.11 Acute cystitis Genitourinary 1.02 0.972 – 1.07 0.399 1783 16452 all phecode
592.12 Chronic cystitis Genitourinary 1.04 0.907 – 1.19 0.574 239 2343 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.977 0.882 – 1.08 0.652 431 4310 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.914 0.793 – 1.05 0.213 210 2093 all phecode
593 Hematuria Genitourinary 1.05 1.01 – 1.08 0.00389 4859 32063 all phecode
593.1 Gross hematuria Genitourinary 1.04 0.989 – 1.1 0.123 1585 14824 all phecode
593.2 Microscopic hematuria Genitourinary 0.996 0.933 – 1.06 0.903 1049 10301 all phecode
594 Urinary calculus Genitourinary 1.09 1.06 – 1.11 2.26e-09 6707 38209 all phecode
594.1 Calculus of kidney Genitourinary 1.09 1.06 – 1.12 2.08e-09 6273 38051 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.12 1 – 1.25 0.0441 366 3638 all phecode
594.3 Calculus of ureter Genitourinary 1.07 1.01 – 1.13 0.0263 1361 13561 all phecode
594.8 Renal colic Genitourinary 1.01 0.905 – 1.13 0.832 356 3560 all phecode
595 Hydronephrosis Genitourinary 1.05 0.999 – 1.11 0.0552 1670 16658 all phecode
596 Other disorders of bladder Genitourinary 1.04 1 – 1.08 0.0357 3074 28020 all phecode
596.1 Bladder neck obstruction Genitourinary 1.06 0.951 – 1.17 0.303 400 3942 all phecode
596.5 Functional disorders of bladder Genitourinary 1.04 0.983 – 1.09 0.186 1719 17049 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.995 0.936 – 1.06 0.865 1211 11998 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.989 0.912 – 1.07 0.785 661 6537 all phecode
597.2 Urinary complications NEC Genitourinary 1.05 0.98 – 1.12 0.175 1049 10479 all phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.02 0.881 – 1.19 0.763 189 1873 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.1 0.917 – 1.32 0.304 138 1356 all phecode
598.4 Other cells and casts in urine Genitourinary 1.06 0.875 – 1.29 0.548 122 1192 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.993 – 1.04 0.192 14168 30681 all phecode
599.1 Urinary obstruction Genitourinary 0.947 0.875 – 1.02 0.174 728 6861 all phecode
599.2 Retention of urine Genitourinary 1.01 0.974 – 1.04 0.736 5034 28305 all phecode
599.3 Dysuria Genitourinary 0.99 0.958 – 1.02 0.534 4397 27849 all phecode
599.4 Urinary incontinence Genitourinary 1.05 1.01 – 1.08 0.00417 5599 26960 all phecode
599.5 Frequency of urination and polyuria Genitourinary 0.992 0.962 – 1.02 0.587 5498 28723 all phecode
599.6 Oliguria and anuria Genitourinary 1.16 1.06 – 1.26 0.000938 599 5902 all phecode
599.7 Urethral discharge Genitourinary 1.11 0.912 – 1.34 0.305 118 1175 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.01 0.983 – 1.04 0.398 5446 27963 all phecode
599.9 Other abnormality of urination Genitourinary 0.98 0.943 – 1.02 0.318 3041 24877 all phecode
600 Hyperplasia of prostate Genitourinary 0.955 0.918 – 0.993 0.0208 4063 11364 all phecode
601 Inflammatory diseases of prostate Genitourinary 1 0.942 – 1.07 0.882 1044 9665 all phecode
601.1 Prostatitis Genitourinary 0.89 0.809 – 0.98 0.0175 477 4596 all phecode
601.11 Acute prostatitis Genitourinary 0.909 0.752 – 1.1 0.323 124 1200 all phecode
601.12 Chronic prostatitis Genitourinary 1.09 0.877 – 1.35 0.448 95 943 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.08 0.968 – 1.19 0.177 389 3822 all phecode
601.4 Balanoposthitis Genitourinary 0.997 0.827 – 1.2 0.972 127 1224 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.18 1 – 1.39 0.0462 161 1591 all phecode
602 Other disorders of prostate Genitourinary 0.909 0.813 – 1.02 0.0901 361 3399 all phecode
602.3 Dysplasia of prostate Genitourinary 1.03 0.81 – 1.32 0.789 77 730 all phecode
603 Other disorders of testis Genitourinary 1.03 0.93 – 1.13 0.608 440 4354 all phecode
603.1 Hydrocele Genitourinary 1.03 0.916 – 1.16 0.595 293 2882 all phecode
603.2 Spermatocele Genitourinary 0.94 0.798 – 1.11 0.458 156 1539 all phecode
604 Disorders of penis Genitourinary 0.963 0.889 – 1.04 0.354 685 6748 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.17 0.986 – 1.38 0.0725 155 1540 all phecode
604.3 Peyronie's disease Genitourinary 0.912 0.792 – 1.05 0.196 215 2132 all phecode
605 Erectile dysfunction [ED] Genitourinary 0.962 0.926 – 0.999 0.0429 3776 12700 all phecode
608 Other disorders of male genital organs Genitourinary 0.982 0.932 – 1.04 0.505 1645 13758 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.941 0.852 – 1.04 0.235 424 4196 all phecode
609.1 Infertility, male Genitourinary 0.946 0.842 – 1.06 0.352 302 2992 all phecode
609.11 Azoospermia and oligospermia Genitourinary 1.15 0.93 – 1.42 0.198 95 950 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.952 0.803 – 1.13 0.57 154 1519 all phecode
610 Benign mammary dysplasias Genitourinary 0.925 0.891 – 0.96 4.17e-05 3683 16548 all phecode
610.1 Cystic mastopathy Genitourinary 0.91 0.863 – 0.96 0.000529 1633 14191 all phecode
610.2 Fibroadenosis of breast Genitourinary 0.839 0.642 – 1.1 0.199 60 600 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.921 0.883 – 0.96 1e-04 2837 16430 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.907 0.854 – 0.964 0.00153 1269 12191 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.925 0.897 – 0.954 6.8e-07 6067 18690 all phecode
611.1 Abnormal mammogram Genitourinary 0.911 0.881 – 0.942 4.86e-08 4980 16120 all phecode
611.11 Mammographic microcalcification Genitourinary 0.86 0.806 – 0.917 4.38e-06 1122 10394 all phecode
611.3 Lump or mass in breast Genitourinary 0.925 0.891 – 0.96 4.59e-05 3549 18572 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.955 0.895 – 1.02 0.167 1051 10425 all phecode
612.1 Galactorrhea Genitourinary 1.02 0.855 – 1.21 0.831 139 1390 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.98 0.909 – 1.06 0.6 800 7962 all phecode
612.3 Congenital anomalies of breast Genitourinary 0.75 0.587 – 0.959 0.0219 83 810 all phecode
613 Other nonmalignant breast conditions Genitourinary 0.976 0.942 – 1.01 0.177 3897 22072 all phecode
613.1 Inflammatory disease of breast Genitourinary 0.976 0.895 – 1.06 0.582 593 5874 all phecode
613.5 Mastodynia Genitourinary 0.989 0.939 – 1.04 0.691 1675 16203 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.909 0.846 – 0.976 0.00893 883 8754 all phecode
613.8 Other specified disorders of breast Genitourinary 0.897 0.836 – 0.962 0.00238 932 9248 all phecode
613.9 Breast disorder NOS Genitourinary 0.964 0.912 – 1.02 0.203 1465 14174 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.01 0.971 – 1.04 0.701 3715 19647 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.967 0.863 – 1.08 0.569 337 3370 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.1 0.999 – 1.21 0.0529 478 4773 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.07 0.857 – 1.33 0.565 94 933 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1 0.857 – 1.17 0.972 186 1842 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.06 0.927 – 1.21 0.394 246 2460 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.05 0.89 – 1.23 0.578 165 1639 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1 0.962 – 1.04 0.972 3180 19539 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.959 0.841 – 1.09 0.535 264 2640 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.994 0.953 – 1.04 0.776 2732 18924 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.18 0.981 – 1.42 0.0787 132 1311 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.05 0.917 – 1.21 0.463 225 2244 all phecode
615 Endometriosis Genitourinary 0.984 0.933 – 1.04 0.558 1585 14666 all phecode
618 Genital prolapse Genitourinary 0.956 0.912 – 1 0.0635 2079 17915 all phecode
618.1 Prolapse of vaginal walls Genitourinary 0.929 0.878 – 0.984 0.0117 1408 13456 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.932 0.85 – 1.02 0.13 542 5390 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.881 0.78 – 0.994 0.0399 317 3162 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.01 0.913 – 1.12 0.842 441 4394 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.978 0.948 – 1.01 0.155 5728 18687 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.978 0.921 – 1.04 0.464 1233 12082 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1.03 0.945 – 1.13 0.485 591 5897 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.921 0.836 – 1.01 0.0948 483 4823 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.968 0.927 – 1.01 0.136 2525 18404 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.995 0.935 – 1.06 0.871 1189 11717 all phecode
620 Dysplasia of female genital organs Genitourinary 0.988 0.889 – 1.1 0.824 395 3950 all phecode
620.1 Dysplasia of cervix Genitourinary 0.915 0.781 – 1.07 0.271 178 1780 all phecode
621 Endometrial hyperplasia Genitourinary 1.1 0.989 – 1.21 0.0815 437 4370 all phecode
622 Polyp of female genital organs Genitourinary 0.952 0.9 – 1.01 0.0865 1449 14264 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.968 0.908 – 1.03 0.316 1132 11189 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.901 0.813 – 0.998 0.0459 445 4444 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.01 0.941 – 1.09 0.723 824 8165 all phecode
624 Symptoms involving female genital tract Genitourinary 0.964 0.91 – 1.02 0.21 1348 12518 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.954 0.824 – 1.1 0.528 216 2155 all phecode
624.2 Atrophy of female genital tract Genitourinary 1.04 0.799 – 1.35 0.779 64 615 all phecode
624.9 stress incontinence, female Genitourinary 1.01 0.96 – 1.06 0.729 1935 15408 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.965 0.935 – 0.996 0.0252 5653 17303 all phecode
625.1 Dyspareunia Genitourinary 0.913 0.86 – 0.969 0.00272 1267 12474 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.985 0.954 – 1.02 0.351 5940 15585 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.988 0.953 – 1.02 0.512 4315 14604 all phecode
626.11 Absent or infrequent menstruation Genitourinary 1.01 0.949 – 1.08 0.694 1062 8531 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1 0.955 – 1.05 0.946 2097 11991 all phecode
626.13 Irregular menstrual cycle Genitourinary 0.971 0.924 – 1.02 0.241 1957 12265 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.977 0.912 – 1.05 0.501 970 8996 all phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.965 0.866 – 1.07 0.511 394 3789 all phecode
626.2 Dysmenorrhea Genitourinary 1.02 0.961 – 1.08 0.534 1373 9857 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.909 0.809 – 1.02 0.104 336 3308 all phecode
626.8 Infertility, female Genitourinary 0.958 0.889 – 1.03 0.267 817 6741 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.938 0.906 – 0.971 0.000335 4560 14557 all phecode
627.1 Postmenopausal bleeding Genitourinary 0.992 0.93 – 1.06 0.795 1146 10338 all phecode
627.2 Symptomatic menopause Genitourinary 0.918 0.881 – 0.957 4.81e-05 3017 13763 all phecode
627.21 Symptomatic artificial menopause Genitourinary 0.921 0.775 – 1.1 0.353 152 1514 all phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.796 0.71 – 0.892 8.85e-05 356 3513 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.911 0.851 – 0.976 0.00753 997 9484 all phecode
627.4 Premenopausal menorrhagia Genitourinary 1.01 0.9 – 1.13 0.906 361 3580 all phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.853 0.756 – 0.963 0.0102 309 3082 all phecode
628 Ovarian cyst Genitourinary 0.984 0.937 – 1.03 0.52 1945 13838 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.965 0.897 – 1.04 0.348 826 8047 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.909 0.798 – 1.03 0.147 273 2715 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.11 0.915 – 1.36 0.281 117 1170 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.904 0.826 – 0.989 0.0272 563 5309 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.893 0.8 – 0.998 0.0453 370 3629 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.879 0.776 – 0.996 0.0433 288 2850 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.959 0.898 – 1.02 0.212 1080 7870 all phecode
636.1 Threatened premature labor Pregnancy Complications 0.952 0.854 – 1.06 0.381 380 3799 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.991 0.873 – 1.12 0.89 288 2868 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.977 0.883 – 1.08 0.645 441 4365 all phecode
636.8 Cervical incompetence Pregnancy Complications 0.908 0.72 – 1.14 0.413 77 770 all phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1 0.801 – 1.26 0.97 85 850 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.07 0.978 – 1.16 0.144 585 5725 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.03 0.909 – 1.16 0.66 302 3013 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.17 1.02 – 1.34 0.0207 252 2506 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.19 0.98 – 1.45 0.0793 119 1190 all phecode
644 Anemia during pregnancy Pregnancy Complications 1.1 0.953 – 1.27 0.194 224 2224 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.01 0.937 – 1.09 0.805 855 6531 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.978 0.847 – 1.13 0.762 211 2093 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.04 0.9 – 1.19 0.619 222 2213 all phecode
647.3 Major puerperal infection Pregnancy Complications 1.04 0.811 – 1.33 0.761 65 650 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.981 0.922 – 1.04 0.538 1275 8010 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1 0.92 – 1.09 0.991 649 5687 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.968 0.886 – 1.06 0.471 587 5463 all phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.05 0.905 – 1.22 0.523 207 2055 all phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 0.97 0.834 – 1.13 0.689 204 2040 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.905 0.857 – 0.956 0.000336 1624 10064 all phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 0.928 0.852 – 1.01 0.092 616 5533 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.05 0.98 – 1.13 0.162 898 7014 all phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 1.16 0.895 – 1.5 0.265 66 660 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.978 0.909 – 1.05 0.539 887 6802 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.975 0.851 – 1.12 0.714 236 2351 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.09 0.923 – 1.28 0.316 158 1580 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.895 0.768 – 1.04 0.152 184 1814 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.11 1.08 – 1.14 3.83e-14 6500 38394 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.04 0.98 – 1.11 0.19 1256 11462 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.14 1.06 – 1.22 0.000148 1007 9981 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.14 1.09 – 1.2 9.2e-09 2123 19952 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.16 1.11 – 1.22 2.64e-11 2252 20944 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.16 1.1 – 1.22 4.47e-09 1820 16893 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.18 1.12 – 1.25 7.24e-10 1572 15588 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.11 1.06 – 1.16 6.27e-06 2257 21750 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.05 0.963 – 1.15 0.251 558 5504 all phecode
686.2 Impetigo Dermatologic 1.04 0.937 – 1.15 0.474 414 4117 all phecode
686.3 Pilonidal cyst Dermatologic 1.18 0.997 – 1.39 0.054 160 1594 all phecode
686.4 Pyogenic granuloma Dermatologic 0.916 0.777 – 1.08 0.296 158 1570 all phecode
686.5 Pyoderma Dermatologic 1.28 0.993 – 1.66 0.0562 63 630 all phecode
687 Symptoms affecting skin Dermatologic 1 0.95 – 1.05 0.999 1690 16343 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.01 0.98 – 1.03 0.614 7007 34623 all phecode
687.3 Changes in skin texture Dermatologic 1.11 1 – 1.24 0.0429 415 4121 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.03 0.999 – 1.06 0.0613 6375 34216 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.96 0.937 – 0.983 0.000679 9311 37335 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.933 0.905 – 0.962 9.51e-06 5184 31581 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.932 0.904 – 0.961 7.9e-06 5174 31553 all phecode
691 Congenital anomalies of skin Dermatologic 0.928 0.847 – 1.02 0.106 541 5337 all phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 0.946 0.727 – 1.23 0.678 62 613 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.928 0.884 – 0.975 0.00285 1861 17936 all phecode
694.1 Vitiligo Dermatologic 1.14 0.952 – 1.37 0.155 137 1347 all phecode
694.2 Other dyschromia Dermatologic 0.917 0.871 – 0.966 0.00104 1674 16183 all phecode
694.3 Vascular disorders of skin Dermatologic 0.985 0.782 – 1.24 0.896 82 819 all phecode
695 Erythematous conditions Dermatologic 1.01 0.974 – 1.04 0.663 4120 30247 all phecode
695.1 Toxic erythema Dermatologic 1.17 0.918 – 1.5 0.204 70 688 all phecode
695.2 Bullous dermatoses Dermatologic 1 0.783 – 1.28 0.999 85 805 all phecode
695.3 Rosacea Dermatologic 0.901 0.857 – 0.948 4.9e-05 1816 17663 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.08 0.994 – 1.17 0.0702 672 6686 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.04 0.906 – 1.19 0.588 247 2437 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.08 0.994 – 1.18 0.0673 637 6337 all phecode
695.7 Prurigo and Lichen Dermatologic 0.952 0.873 – 1.04 0.261 605 5986 all phecode
695.8 Other specified erythematous conditions Dermatologic 1.11 1.03 – 1.19 0.00646 812 7980 all phecode
695.81 Erythema nodosum Dermatologic 0.931 0.701 – 1.24 0.621 55 550 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.11 1.02 – 1.2 0.0111 679 6756 all phecode
696 Psoriasis and related disorders Dermatologic 1.05 0.992 – 1.11 0.0952 1401 13832 all phecode
696.3 Pityriasis Dermatologic 0.953 0.769 – 1.18 0.661 92 904 all phecode
696.4 Psoriasis Dermatologic 1.06 0.998 – 1.12 0.06 1311 12976 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.05 0.989 – 1.12 0.108 1200 11867 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.05 0.925 – 1.19 0.463 282 2810 all phecode
697 Sarcoidosis Dermatologic 1.05 0.933 – 1.17 0.437 333 3330 all phecode
698 Pruritus and related conditions Dermatologic 1 0.957 – 1.05 0.986 2254 21889 all phecode
700 Corns and callosities Dermatologic 1.08 1.01 – 1.14 0.015 1373 10894 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1 0.977 – 1.03 0.867 7651 38050 all phecode
701.1 Keratoderma, acquired Dermatologic 1.06 0.971 – 1.16 0.189 567 5524 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.942 0.9 – 0.985 0.00957 2184 21550 all phecode
701.3 Circumscribed scleroderma Dermatologic 0.988 0.903 – 1.08 0.798 571 5660 all phecode
701.4 Keloid scar Dermatologic 0.935 0.857 – 1.02 0.132 578 5716 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.1 0.988 – 1.22 0.081 400 3982 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.91 0.885 – 0.935 2.64e-11 6956 29525 all phecode
702.1 Actinic keratosis Dermatologic 0.881 0.851 – 0.912 5.44e-13 4171 26529 all phecode
702.2 Seborrheic keratosis Dermatologic 0.907 0.88 – 0.935 3.05e-10 5480 31552 all phecode
702.4 Degenerative skin disorders Dermatologic 1.13 0.899 – 1.42 0.292 86 832 all phecode
703 Diseases of nail, NOS Dermatologic 1.03 0.979 – 1.09 0.243 1650 14562 all phecode
703.1 Ingrowing nail Dermatologic 1.07 0.996 – 1.14 0.0662 920 8597 all phecode
704 Diseases of hair and hair follicles Dermatologic 0.948 0.912 – 0.985 0.00582 3118 29542 all phecode
704.1 Alopecia Dermatologic 0.912 0.862 – 0.965 0.0014 1408 13871 all phecode
704.11 Alopecia Areata Dermatologic 0.966 0.775 – 1.2 0.759 82 811 all phecode
704.12 Telogen effluvium Dermatologic 0.85 0.652 – 1.11 0.231 63 615 all phecode
704.2 Hirsutism Dermatologic 1.33 1.18 – 1.51 2.79e-06 299 2946 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.98 0.932 – 1.03 0.43 1752 17189 all phecode
705 Disorders of sweat glands Dermatologic 1.19 1.09 – 1.3 8.36e-05 603 6012 all phecode
705.1 Dyshidrosis Dermatologic 1.08 0.906 – 1.28 0.398 154 1540 all phecode
705.3 Hidradenitis Dermatologic 1.35 1.17 – 1.55 2.52e-05 245 2440 all phecode
705.8 Hyperhidrosis Dermatologic 0.999 0.938 – 1.07 0.984 1112 10986 all phecode
706 Diseases of sebaceous glands Dermatologic 0.938 0.911 – 0.964 7.26e-06 5995 39748 all phecode
706.1 Acne Dermatologic 0.891 0.854 – 0.929 6.45e-08 2594 22570 all phecode
706.2 Sebaceous cyst Dermatologic 0.959 0.921 – 0.998 0.039 2814 26819 all phecode
706.3 Seborrhea Dermatologic 0.9 0.689 – 1.18 0.442 59 582 all phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 1.01 0.957 – 1.06 0.774 1684 15289 all phecode
707 Chronic ulcer of skin Dermatologic 1.15 1.11 – 1.2 4.62e-12 2871 26816 all phecode
707.1 Decubitus ulcer Dermatologic 1.17 1.09 – 1.26 2.62e-05 825 8119 all phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.24 1.16 – 1.32 6.56e-11 1108 9992 all phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1.13 1.07 – 1.19 8.55e-06 1641 16172 all phecode
709 Diffuse diseases of connective tissue Dermatologic 1.01 0.959 – 1.07 0.644 1477 14427 all phecode
709.2 Sicca syndrome Dermatologic 1.01 0.92 – 1.11 0.836 505 4986 all phecode
709.3 Systemic sclerosis Dermatologic 0.883 0.769 – 1.01 0.0761 224 2209 all phecode
709.5 Dermatomyositis Dermatologic 1.17 0.949 – 1.45 0.14 92 892 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.13 0.903 – 1.42 0.285 90 892 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.02 0.952 – 1.09 0.563 917 9089 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.18 1.11 – 1.25 3.96e-08 1254 12103 all phecode
710.1 Osteomyelitis Musculoskeletal 1.18 1.11 – 1.25 1.47e-07 1203 11636 all phecode
710.11 Acute osteomyelitis Musculoskeletal 1.31 1.2 – 1.43 2.59e-09 590 5708 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.22 1.11 – 1.33 3.65e-05 531 5163 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.18 1.11 – 1.25 2.64e-07 1153 11149 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.14 1.03 – 1.27 0.0123 410 4099 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.27 1.12 – 1.44 0.00015 290 2900 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.26 1.07 – 1.48 0.00461 178 1776 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.19 1.05 – 1.34 0.00486 314 3028 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.26 1.08 – 1.47 0.00409 194 1824 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.12 1.06 – 1.17 5.2e-06 2086 18159 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.14 1.08 – 1.2 7.99e-07 1670 15087 all phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.05 0.838 – 1.32 0.661 77 767 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.11 1.04 – 1.18 0.00115 1209 11967 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.21 1.06 – 1.37 0.00431 262 2611 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.08 0.933 – 1.24 0.309 219 2182 all phecode
716 Other arthropathies Musculoskeletal 1.12 1.09 – 1.14 4.64e-23 13482 31305 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.04 0.894 – 1.21 0.601 192 1920 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.886 0.736 – 1.07 0.201 131 1293 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.12 1.09 – 1.14 3.4e-23 13410 31294 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.989 0.867 – 1.13 0.869 261 2565 all phecode
720 Spinal stenosis Musculoskeletal 1.09 1.05 – 1.13 1.52e-06 3958 28539 all phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1.11 1.07 – 1.16 3.79e-07 2872 23656 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1.05 1.02 – 1.08 0.000702 5509 32391 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.05 1.02 – 1.08 0.00152 5153 31896 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.03 0.959 – 1.11 0.407 867 8629 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.18 1.04 – 1.35 0.0116 262 2600 all phecode
722 Intervertebral disc disorders Musculoskeletal 1.07 1.04 – 1.1 1.53e-06 6284 34317 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.07 1.03 – 1.11 0.00014 3591 31411 all phecode
722.3 Schmorl's nodes Musculoskeletal 1 0.826 – 1.21 0.989 126 1248 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.07 1.03 – 1.11 0.000141 3957 30744 all phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.01 0.915 – 1.11 0.889 515 5140 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.06 0.953 – 1.18 0.29 397 3968 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.02 0.97 – 1.07 0.457 1932 19288 all phecode
723 Other disorders of cervical region Musculoskeletal 0.993 0.927 – 1.06 0.829 952 9495 all phecode
723.1 Torticollis Musculoskeletal 1.01 0.886 – 1.15 0.865 254 2522 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.05 1.02 – 1.09 0.00184 4130 31954 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.07 1.02 – 1.12 0.00289 2307 21902 all phecode
724.2 Disorders of coccyx Musculoskeletal 1.01 0.907 – 1.12 0.913 426 4215 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.1 1.03 – 1.18 0.00753 931 9295 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.04 0.984 – 1.1 0.16 1412 14087 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.98 0.957 – 1 0.0986 9917 30176 all phecode
726.1 Enthesopathy Musculoskeletal 0.974 0.949 – 1 0.052 7507 30106 all phecode
726.2 Synoviopathy Musculoskeletal 0.96 0.898 – 1.03 0.236 1015 9987 all phecode
726.3 Bursitis Musculoskeletal 0.984 0.936 – 1.03 0.52 1829 16722 all phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.992 0.933 – 1.05 0.795 1193 11485 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1 0.974 – 1.03 0.967 7425 30105 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.01 0.975 – 1.05 0.489 3092 24998 all phecode
727.2 Bursitis disorders Musculoskeletal 0.99 0.892 – 1.1 0.848 419 4112 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.964 0.911 – 1.02 0.206 1400 13621 all phecode
727.5 Rupture of synovium Musculoskeletal 1.07 0.971 – 1.18 0.167 480 4672 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.983 0.941 – 1.03 0.436 2461 21948 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.998 0.915 – 1.09 0.966 591 5893 all phecode
727.8 Plica syndrome Musculoskeletal 0.907 0.752 – 1.09 0.307 130 1264 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.02 0.988 – 1.05 0.217 4546 29473 all phecode
728.1 Muscular calcification and ossification Musculoskeletal 0.903 0.718 – 1.14 0.382 85 843 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.911 0.808 – 1.03 0.13 297 2949 all phecode
728.7 Fasciitis Musculoskeletal 0.977 0.938 – 1.02 0.265 2814 23463 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.844 0.761 – 0.936 0.00133 419 4138 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.1 1.06 – 1.14 2.54e-07 3642 27471 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.02 0.793 – 1.31 0.872 74 726 all phecode
729.3 Panniculitis Musculoskeletal 1.15 0.947 – 1.39 0.16 119 1174 all phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 1.02 0.784 – 1.32 0.897 67 664 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.24 1.07 – 1.43 0.00323 210 2091 all phecode
732 Osteochondropathies Musculoskeletal 1.14 1.02 – 1.27 0.0244 361 3604 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.21 1.04 – 1.41 0.0135 198 1969 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.01 0.812 – 1.27 0.897 90 882 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.924 0.894 – 0.955 3.48e-06 4543 26941 all phecode
733.2 Cyst of bone Musculoskeletal 1 0.859 – 1.17 0.974 190 1900 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.975 0.889 – 1.07 0.592 518 5160 all phecode
733.6 Costochondritis Musculoskeletal 0.923 0.826 – 1.03 0.158 357 3562 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.06 0.982 – 1.14 0.136 822 8205 all phecode
733.9 Chondromalacia Musculoskeletal 0.949 0.769 – 1.17 0.627 96 960 all phecode
735 Acquired foot deformities Musculoskeletal 0.979 0.944 – 1.02 0.255 3417 29622 all phecode
735.1 Flat foot Musculoskeletal 0.966 0.888 – 1.05 0.426 620 6092 all phecode
735.2 Acquired toe deformities Musculoskeletal 0.989 0.932 – 1.05 0.702 1323 11983 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.02 0.95 – 1.1 0.544 825 7494 all phecode
735.23 Hallux rigidus Musculoskeletal 0.94 0.847 – 1.04 0.245 405 4005 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.938 0.888 – 0.992 0.0244 1470 14295 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.993 0.954 – 1.03 0.745 2763 26555 all phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.931 0.756 – 1.15 0.504 104 1033 all phecode
736.2 Acquired deformities of finger Musculoskeletal 0.939 0.811 – 1.09 0.396 215 2142 all phecode
736.3 Acquired deformities of hip Musculoskeletal 0.977 0.741 – 1.29 0.869 60 590 all phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 1.01 0.9 – 1.14 0.851 325 3247 all phecode
736.5 Acquired deformities of knee Musculoskeletal 0.992 0.87 – 1.13 0.903 246 2460 all phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.967 0.864 – 1.08 0.561 339 3365 all phecode
737 Curvature of spine Musculoskeletal 0.956 0.906 – 1.01 0.103 1566 15543 all phecode
737.1 Kyphosis (acquired) Musculoskeletal 1.02 0.928 – 1.13 0.665 479 4748 all phecode
737.2 Lordosis (acquired) Musculoskeletal 1.21 0.934 – 1.56 0.149 70 700 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.94 0.884 – 0.999 0.0468 1203 11982 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.993 0.952 – 1.04 0.758 2443 24187 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.08 1.01 – 1.15 0.0237 1057 10542 all phecode
739 Contracture of joint Musculoskeletal 0.953 0.875 – 1.04 0.27 621 6207 all phecode
740 Osteoarthrosis Musculoskeletal 1.12 1.1 – 1.15 3.36e-28 16169 30268 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.09 1.06 – 1.12 4.23e-10 7005 27422 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.08 1.05 – 1.12 1.44e-07 6176 26155 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.13 1.04 – 1.22 0.00358 713 7116 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.05 0.995 – 1.11 0.0728 1609 12092 all phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 1.12 1 – 1.25 0.0475 373 3586 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.13 1.1 – 1.15 1.69e-28 15497 30141 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.02 0.992 – 1.04 0.188 8555 35884 all phecode
741.1 Ankylosis of joint Musculoskeletal 0.997 0.871 – 1.14 0.963 245 2445 all phecode
741.2 Stiffness of joint Musculoskeletal 0.974 0.917 – 1.03 0.386 1268 12594 all phecode
741.3 Difficulty in walking Musculoskeletal 1.07 1.02 – 1.11 0.00219 2558 23116 all phecode
741.4 Joint effusions Musculoskeletal 1.02 0.977 – 1.06 0.374 2493 24199 all phecode
741.5 Hemarthrosis Musculoskeletal 1.02 0.825 – 1.27 0.827 94 937 all phecode
741.6 Villonodular synovitis Musculoskeletal 0.88 0.673 – 1.15 0.35 68 666 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.01 0.977 – 1.04 0.576 4404 33771 all phecode
742.1 Loose body in joint Musculoskeletal 1.21 1.03 – 1.43 0.0218 156 1554 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.898 0.793 – 1.02 0.088 280 2792 all phecode
742.8 Articular cartilage disorder Musculoskeletal 0.951 0.83 – 1.09 0.471 245 2450 all phecode
742.9 Other derangement of joint Musculoskeletal 1.01 0.978 – 1.04 0.532 4107 32972 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.944 0.921 – 0.967 4.21e-06 9223 36921 all phecode
743.1 Osteoporosis Musculoskeletal 0.94 0.905 – 0.976 0.00134 3712 19477 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.936 0.901 – 0.972 0.000682 3657 19276 all phecode
743.12 Senile osteoporosis Musculoskeletal 0.841 0.774 – 0.913 3.57e-05 703 5804 all phecode
743.13 Other specified osteoporosis Musculoskeletal 0.951 0.846 – 1.07 0.399 321 3141 all phecode
743.2 Pathologic fracture Musculoskeletal 0.949 0.89 – 1.01 0.108 1112 10563 all phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 0.958 0.868 – 1.06 0.385 475 4629 all phecode
743.22 Pathologic fracture of femur Musculoskeletal 0.935 0.782 – 1.12 0.466 143 1391 all phecode
743.4 Stress fracture Musculoskeletal 0.951 0.856 – 1.06 0.345 407 4046 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.933 0.908 – 0.959 6.72e-07 6970 35237 all phecode
745 Pain in joint Musculoskeletal 0.994 0.975 – 1.01 0.537 19848 26918 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.98 0.937 – 1.02 0.37 2236 22256 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1 0.954 – 1.05 0.911 1767 17598 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.927 0.853 – 1.01 0.0729 650 6497 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.991 0.918 – 1.07 0.82 751 7480 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.11 0.998 – 1.23 0.054 410 4090 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.915 0.832 – 1.01 0.0674 501 5010 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.12 0.918 – 1.38 0.258 111 1110 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.945 0.864 – 1.03 0.211 555 5549 all phecode
749.1 Cleft palate Congenital Anomalies 0.88 0.717 – 1.08 0.218 97 970 all phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.932 0.763 – 1.14 0.487 105 1041 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.966 0.899 – 1.04 0.338 893 8919 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.968 0.865 – 1.08 0.562 366 3655 all phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.947 0.78 – 1.15 0.582 119 1185 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.873 0.707 – 1.08 0.21 99 982 all phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 0.932 0.778 – 1.12 0.446 134 1332 all phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 1.18 0.894 – 1.54 0.248 60 593 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.942 0.858 – 1.03 0.208 531 5300 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.866 0.77 – 0.976 0.0178 313 3129 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.08 0.939 – 1.25 0.273 222 2214 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1 0.958 – 1.05 0.856 2008 19975 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.974 0.892 – 1.06 0.551 574 5740 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.958 0.86 – 1.07 0.438 384 3840 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.997 0.843 – 1.18 0.975 153 1527 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.01 0.952 – 1.07 0.79 1379 13704 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.991 0.925 – 1.06 0.79 976 9685 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.01 0.891 – 1.14 0.919 294 2927 all phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.05 0.896 – 1.22 0.562 182 1809 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.11 1.04 – 1.18 0.0017 1133 11313 all phecode
752.1 Neural tube defects Congenital Anomalies 1.13 1.05 – 1.21 0.000939 923 9209 all phecode
752.11 Spina bifida Congenital Anomalies 1.08 0.916 – 1.26 0.377 176 1760 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.995 0.865 – 1.14 0.941 232 2320 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.08 0.928 – 1.26 0.319 207 2051 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.987 0.752 – 1.3 0.926 58 580 all phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 1.1 0.825 – 1.46 0.524 56 546 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.07 1.01 – 1.14 0.0215 1216 12116 all phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 1.13 0.944 – 1.36 0.179 135 1333 all phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 1.09 0.994 – 1.19 0.0674 558 5570 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.04 0.96 – 1.12 0.348 747 7458 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.955 0.856 – 1.07 0.416 368 3663 all phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 1.12 0.881 – 1.43 0.351 74 740 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.08 0.959 – 1.21 0.208 321 3205 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.09 0.934 – 1.27 0.275 185 1847 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.991 0.936 – 1.05 0.77 1358 13579 all phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 1.1 0.852 – 1.41 0.473 68 680 all phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 0.944 0.736 – 1.21 0.65 71 694 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.948 0.845 – 1.06 0.361 335 3346 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.01 0.947 – 1.08 0.721 1003 10014 all phecode
757 Congenital anomalies of the integument Congenital Anomalies 0.879 0.791 – 0.977 0.0163 401 4001 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.895 0.767 – 1.05 0.162 185 1845 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.822 0.687 – 0.984 0.0327 135 1349 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.02 0.931 – 1.11 0.694 557 5566 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.02 0.796 – 1.3 0.88 71 710 all phecode
760 Back pain Symptoms 1.05 1.03 – 1.07 2.32e-06 16037 30719 all phecode
761 Cervicalgia Symptoms 1 0.975 – 1.03 0.902 6528 39755 all phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 1.05 1.01 – 1.09 0.00897 3657 32599 all phecode
764 Sciatica Symptoms 1.08 1.04 – 1.12 6.12e-05 3542 32015 all phecode
765 Cervical radiculitis Symptoms 1 0.954 – 1.05 0.902 1799 17851 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.04 1.01 – 1.08 0.00584 5124 37132 all phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 0.926 0.764 – 1.12 0.438 117 1168 all phecode
769 Nonallopathic lesions NEC Symptoms 0.968 0.909 – 1.03 0.303 1131 11220 all phecode
770 Myalgia and myositis unspecified Symptoms 1.06 1.03 – 1.09 0.000205 5533 34303 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.05 1.02 – 1.09 0.000764 4799 35575 all phecode
771.1 Swelling of limb Symptoms 1.11 1.08 – 1.14 8.84e-13 5743 35539 all phecode
771.2 Cramp of limb Symptoms 1.03 0.964 – 1.1 0.401 1079 10568 all phecode
772 Symptoms of the muscles Symptoms 0.932 0.889 – 0.977 0.00315 2042 20221 all phecode
772.1 Muscular wasting and disuse atrophy Symptoms 0.96 0.866 – 1.06 0.442 422 4199 all phecode
772.2 Spasm of muscle Symptoms 1.01 0.97 – 1.06 0.539 2299 22726 all phecode
772.3 Muscle weakness Symptoms 1.03 0.995 – 1.08 0.0902 2949 28064 all phecode
772.4 Rhabdomyolysis Symptoms 1.2 1.01 – 1.42 0.0387 159 1572 all phecode
772.6 Facial weakness Symptoms 0.965 0.876 – 1.06 0.479 478 4742 all phecode
780 Hypothermia/Chills Symptoms 1 0.907 – 1.11 0.952 453 4514 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.01 0.973 – 1.05 0.542 2822 26225 all phecode
781.1 Loss of height Symptoms 0.987 0.814 – 1.2 0.891 130 1269 all phecode
781.2 Abnormal posture Symptoms 0.868 0.666 – 1.13 0.294 57 567 all phecode
782.3 Edema Symptoms 1.17 1.14 – 1.2 2.07e-26 5874 36788 all phecode
782.6 Pallor and flushing Symptoms 0.923 0.86 – 0.99 0.0247 927 9252 all phecode
783 Fever of unknown origin Symptoms 1.07 1.04 – 1.1 1.5e-06 5733 40720 all phecode
783.1 Postprocedural fever Symptoms 1.07 0.951 – 1.21 0.247 300 2992 all phecode
785 Abdominal pain Symptoms 1.04 1.02 – 1.06 3.85e-05 16458 30297 all phecode
788 Syncope and collapse Symptoms 1.01 0.975 – 1.04 0.625 3851 35832 all phecode
789 Nausea and vomiting Symptoms 1.03 1.01 – 1.05 0.00896 10568 36098 all phecode
789.1 Persistent vomiting Symptoms 1.12 1.04 – 1.2 0.00352 798 7924 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.09 1.04 – 1.14 0.000145 2363 22690 all phecode
790.1 Elevated sedimentation rate Symptoms 1.08 0.941 – 1.23 0.282 236 2322 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.07 1.04 – 1.1 7.72e-07 7539 37788 all phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.23 1.09 – 1.38 0.000662 309 3075 all phecode
790.9 Abnormal arterial blood gases Symptoms 1.3 1.1 – 1.55 0.00278 155 1521 all phecode
791 Gangrene Symptoms 1.25 1.11 – 1.41 0.000282 313 3115 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 0.973 0.934 – 1.01 0.207 2820 14872 all phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 0.968 0.908 – 1.03 0.329 1100 9861 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.95 0.865 – 1.04 0.279 515 5133 all phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 1 0.956 – 1.05 0.996 2182 20242 all phecode
795.8 Abnormal tumor markers Symptoms 0.921 0.875 – 0.969 0.00151 1745 15551 all phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 1.03 0.793 – 1.34 0.822 61 605 all phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 0.937 0.806 – 1.09 0.398 201 2000 all phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.885 0.842 – 0.93 1.16e-06 2125 9930 all phecode
797 Shock Symptoms 1.07 0.984 – 1.17 0.111 605 6050 all phecode
797.1 Cardiogenic shock Symptoms 1.17 1.03 – 1.35 0.0202 242 2420 all phecode
798 Malaise and fatigue Symptoms 1.01 0.989 – 1.03 0.347 11539 35196 all phecode
798.1 Chronic fatigue syndrome Symptoms 1.03 0.98 – 1.08 0.245 1823 17795 all phecode
800 Fracture of lower limb Injuries & Poisonings 0.988 0.945 – 1.03 0.579 2344 22951 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.957 0.872 – 1.05 0.356 512 4961 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.954 0.879 – 1.03 0.257 670 6582 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.02 0.95 – 1.09 0.589 898 8966 all phecode
800.4 Fracture of patella Injuries & Poisonings 0.981 0.877 – 1.1 0.74 346 3456 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.02 0.972 – 1.06 0.501 2358 22645 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.02 0.956 – 1.09 0.565 1120 11178 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.928 0.833 – 1.03 0.177 380 3765 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.936 0.893 – 0.98 0.00512 2051 20360 all phecode
803.1 Fracture of humerus Injuries & Poisonings 0.991 0.917 – 1.07 0.829 734 7322 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.92 0.864 – 0.979 0.00912 1112 11075 all phecode
803.21 Colles' fracture Injuries & Poisonings 0.864 0.765 – 0.976 0.0188 291 2904 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.888 0.809 – 0.974 0.0117 514 5140 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.94 0.892 – 0.991 0.0207 1628 16042 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.973 0.918 – 1.03 0.351 1336 13242 all phecode
807 Fracture of ribs Injuries & Poisonings 0.958 0.884 – 1.04 0.301 683 6815 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.965 0.928 – 1 0.0742 2941 28633 all phecode
816 Cerebral laceration and contusion Injuries & Poisonings 1.05 0.794 – 1.39 0.733 54 531 all phecode
817 Concussion Injuries & Poisonings 0.992 0.929 – 1.06 0.818 1018 10149 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.896 0.795 – 1.01 0.0691 311 3104 all phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.879 0.706 – 1.09 0.25 90 895 all phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 0.962 0.777 – 1.19 0.722 97 970 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.973 0.931 – 1.02 0.223 2287 22671 all phecode
830 Dislocation Injuries & Poisonings 0.967 0.934 – 1 0.0516 3862 34720 all phecode
835 Internal derangement of knee Injuries & Poisonings 0.993 0.95 – 1.04 0.769 2231 21628 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.08 0.983 – 1.19 0.108 496 4954 all phecode
840 Sprains and strains Injuries & Poisonings 0.974 0.949 – 0.998 0.0371 7838 37998 all phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.992 0.904 – 1.09 0.859 537 5356 all phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 1.01 0.954 – 1.06 0.851 1640 16263 all phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.937 0.9 – 0.975 0.00129 2875 24879 all phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.97 0.92 – 1.02 0.26 1583 15592 all phecode
842 Other sprains and strains Injuries & Poisonings 0.943 0.892 – 0.997 0.0405 1407 13924 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.1 1.05 – 1.15 4.06e-05 2072 20649 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.13 1.09 – 1.18 5.51e-10 2982 27545 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.09 0.991 – 1.2 0.0746 460 4600 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.15 1.1 – 1.21 5.91e-09 1985 19675 all phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.02 0.899 – 1.17 0.724 264 2640 all phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.05 0.929 – 1.19 0.426 293 2929 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.11 1.05 – 1.18 0.000298 1310 13087 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.06 1.01 – 1.1 0.0178 2213 21944 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.07 1.02 – 1.12 0.00291 2110 21070 all phecode
860 Bone marrow or stem cell transplant Neoplasms 0.952 0.808 – 1.12 0.553 166 1660 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.05 1.01 – 1.08 0.00526 4117 36734 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.01 0.871 – 1.17 0.897 204 2026 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.92 0.776 – 1.09 0.338 144 1437 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.909 0.858 – 0.963 0.0012 1346 13301 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.971 0.839 – 1.12 0.695 207 2057 all phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 0.895 0.788 – 1.02 0.0886 275 2724 all phecode
870.6 Open wound of neck Injuries & Poisonings 0.931 0.805 – 1.08 0.33 214 2128 all phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.17 0.98 – 1.39 0.0831 144 1440 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.04 0.999 – 1.07 0.0553 3530 32903 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.03 0.943 – 1.13 0.5 572 5701 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.938 0.876 – 1 0.0643 984 9772 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.22 1.11 – 1.34 4.86e-05 490 4843 all phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.19 1.05 – 1.34 0.00698 295 2921 all phecode
872 Traumatic amputation Injuries & Poisonings 1.16 1.06 – 1.27 0.0013 551 5477 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.25 1.07 – 1.47 0.0063 170 1697 all phecode
875 Non-healing surgical wound Injuries & Poisonings 1.18 1.08 – 1.29 0.000257 572 5720 all phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.24 1.15 – 1.34 1.27e-08 802 8003 all phecode
907 Injuries to the nervous system Injuries & Poisonings 0.971 0.909 – 1.04 0.393 1010 10096 all phecode
910 Superficial injury, infected Injuries & Poisonings 0.944 0.782 – 1.14 0.549 119 1161 all phecode
911 Blister Injuries & Poisonings 1.17 1.03 – 1.32 0.0119 302 2996 all phecode
912 Insect bite Injuries & Poisonings 0.993 0.903 – 1.09 0.886 492 4886 all phecode
913 Toxic effect of venom Injuries & Poisonings 0.855 0.763 – 0.957 0.00671 337 3326 all phecode
916 Contusion Injuries & Poisonings 1.02 0.989 – 1.06 0.204 4296 38033 all phecode
930 Allergic reaction to food Injuries & Poisonings 1.04 0.965 – 1.12 0.295 763 7596 all phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.979 0.904 – 1.06 0.595 714 7072 all phecode
938 Dermatitis due to solar radiation Dermatologic 0.919 0.892 – 0.947 4.54e-08 5567 29098 all phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.96 0.832 – 1.11 0.576 217 2164 all phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.913 0.886 – 0.942 7.89e-09 5307 28656 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.967 0.941 – 0.994 0.0164 6704 32389 all phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 0.935 0.742 – 1.18 0.571 91 870 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.08 0.932 – 1.26 0.296 188 1880 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.02 0.892 – 1.16 0.819 269 2688 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.967 0.88 – 1.06 0.483 500 4940 all phecode
947 Urticaria Dermatologic 0.971 0.913 – 1.03 0.357 1177 11454 all phecode
949 Allergies, other Injuries & Poisonings 1.01 0.982 – 1.04 0.523 7251 32350 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.06 0.965 – 1.17 0.223 494 4940 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.904 0.754 – 1.08 0.276 136 1352 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.08 1.02 – 1.15 0.0108 1217 12158 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.07 0.902 – 1.26 0.455 169 1688 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.83 0.682 – 1.01 0.0641 114 1140 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.11 1.07 – 1.16 7.76e-07 2479 22087 all phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 1.11 0.988 – 1.24 0.0806 342 3403 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.1 1.05 – 1.16 0.000241 1636 16005 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.09 0.998 – 1.2 0.0562 528 5234 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.1 1.03 – 1.18 0.00322 1065 10347 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.07 0.995 – 1.16 0.0668 803 7976 all phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.07 0.961 – 1.2 0.212 379 3782 all phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 1.19 0.925 – 1.54 0.173 62 612 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.954 – 1.16 0.308 478 4773 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.01 0.97 – 1.06 0.579 2533 24531 all phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.02 0.976 – 1.06 0.398 2469 24057 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.1 1.02 – 1.19 0.0177 743 7337 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.1 1.02 – 1.19 0.0177 712 7027 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.03 0.96 – 1.11 0.39 864 8601 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.16 1.1 – 1.23 1.8e-07 1469 14402 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.02 0.847 – 1.23 0.831 119 1182 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.947 0.774 – 1.16 0.597 103 1006 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.989 0.931 – 1.05 0.728 1254 12464 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.19 1.05 – 1.35 0.00608 281 2797 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.09 0.837 – 1.41 0.533 67 643 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.14 1.01 – 1.29 0.0412 288 2858 all phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 1.19 0.947 – 1.49 0.137 80 776 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.14 0.939 – 1.39 0.182 104 1034 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.05 0.868 – 1.27 0.608 113 1130 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.1 0.868 – 1.4 0.422 81 810 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.08 0.839 – 1.39 0.545 71 703 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.11 1.06 – 1.17 3.47e-05 1763 16599 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.04 1.01 – 1.08 0.0185 3448 30885 all phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 1.04 0.981 – 1.1 0.202 1391 13877 all phecode
985 Toxic effect of other metals Injuries & Poisonings 1 0.763 – 1.32 0.984 57 564 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.06 0.881 – 1.27 0.54 129 1275 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.01 0.978 – 1.05 0.476 3927 31223 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.15 1.1 – 1.2 1.59e-09 2192 21710 all phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.15 1.02 – 1.31 0.0221 291 2910 all phecode
994.2 Sepsis Injuries & Poisonings 1.15 1.1 – 1.21 3.29e-09 2086 20666 all phecode
994.21 Septic shock Injuries & Poisonings 1.16 1.07 – 1.26 0.000567 627 6260 all phecode
008 Intestinal infection Infectious Diseases 1.04 0.958 – 1.12 0.378 745 6950 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.24 1.1 – 1.4 0.000386 321 2987 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.25 1.09 – 1.43 0.00136 251 2331 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.09 0.926 – 1.28 0.3 168 1792 exclusion phecode
010 Tuberculosis Infectious Diseases 1.01 0.777 – 1.3 0.965 61 539 exclusion phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.877 0.582 – 1.32 0.53 27 197 exclusion phecode
038 Septicemia Infectious Diseases 1.27 1.16 – 1.39 2.15e-07 551 5136 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.29 1.06 – 1.57 0.0112 115 1172 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.55 1.15 – 2.1 0.00428 50 455 exclusion phecode
038.3 Bacteremia Infectious Diseases 1.25 1.1 – 1.42 0.000767 266 2396 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.14 1.07 – 1.21 2.45e-05 1319 9006 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.3 1.16 – 1.46 5.68e-06 349 3617 exclusion phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.35 1.16 – 1.58 0.000142 181 1916 exclusion phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.31 1.11 – 1.56 0.00191 157 1700 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.24 1.11 – 1.38 0.000124 381 3462 exclusion phecode
041.21 Rheumatic fever / chorea Infectious Diseases 1.02 0.761 – 1.37 0.897 50 554 exclusion phecode
041.4 E. coli Infectious Diseases 1.34 1.17 – 1.54 1.99e-05 260 2614 exclusion phecode
041.8 H. pylori Infectious Diseases 1.03 0.775 – 1.36 0.853 58 595 exclusion phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.46 1.17 – 1.83 0.00103 96 849 exclusion phecode
053 Herpes zoster Infectious Diseases 0.958 0.858 – 1.07 0.443 369 3324 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.01 0.752 – 1.36 0.94 50 459 exclusion phecode
054 Herpes simplex Infectious Diseases 1.02 0.922 – 1.14 0.668 422 3794 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.12 0.956 – 1.3 0.165 193 1614 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.69 0.874 – 3.25 0.119 11 160 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 1.04 0.778 – 1.39 0.784 52 441 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.18 0.979 – 1.42 0.0821 129 966 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.12 0.822 – 1.53 0.47 53 395 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.22 1.07 – 1.4 0.00405 245 2187 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.56 1.16 – 2.08 0.00282 59 289 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.54 1.1 – 2.15 0.0117 50 218 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.926 0.862 – 0.995 0.035 911 7141 exclusion phecode
079 Viral infection Infectious Diseases 0.998 0.946 – 1.05 0.946 1707 8160 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.933 0.871 – 1 0.0514 975 7161 exclusion phecode
079.2 Infectious mononucleosis Infectious Diseases 0.783 0.632 – 0.969 0.0245 106 885 exclusion phecode
079.9 Viremia, NOS Infectious Diseases 1.18 1.03 – 1.37 0.0216 214 2028 exclusion phecode
080 Postoperative infection Infectious Diseases 1.17 1.07 – 1.29 0.000523 540 5845 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.21 1.09 – 1.35 0.00057 389 3473 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.951 0.837 – 1.08 0.443 277 2444 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.01 0.925 – 1.09 0.896 644 6718 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 1.01 0.922 – 1.1 0.85 555 6022 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.986 0.878 – 1.11 0.808 340 3534 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.09 0.903 – 1.31 0.376 129 1645 exclusion phecode
110.13 Dermatophytosis of the body Infectious Diseases 0.828 0.692 – 0.992 0.0403 131 1711 exclusion phecode
110.2 Dermatomycoses Infectious Diseases 1.01 0.822 – 1.25 0.912 103 952 exclusion phecode
112 Candidiasis Infectious Diseases 1.14 1.06 – 1.23 0.000381 876 7564 exclusion phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.09 0.832 – 1.42 0.542 57 1616 exclusion phecode
117 Mycoses Infectious Diseases 1.13 0.962 – 1.34 0.133 164 1439 exclusion phecode
117.1 Histoplasmosis Infectious Diseases 0.927 0.611 – 1.41 0.723 23 193 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.46 1.07 – 1.99 0.0181 49 340 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.812 0.597 – 1.1 0.184 48 434 exclusion phecode
130.1 Lyme disease Infectious Diseases 0.788 0.553 – 1.12 0.186 38 309 exclusion phecode
131 Protozoan infection Infectious Diseases 1.23 0.67 – 2.24 0.508 11 163 exclusion phecode
132 Infestation (lice, mites) Infectious Diseases 1.32 0.976 – 1.77 0.0714 46 468 exclusion phecode
134 Helminthiases Infectious Diseases 1.52 0.905 – 2.56 0.113 22 177 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.56 0.836 – 2.92 0.162 16 108 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.09 1.02 – 1.17 0.0173 854 7457 exclusion phecode
145 Cancer of mouth Neoplasms 1.18 1.06 – 1.31 0.00263 402 2723 exclusion phecode
145.1 Cancer of lip Neoplasms 1.47 0.901 – 2.41 0.122 16 137 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.16 0.991 – 1.36 0.0642 186 1121 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.977 0.773 – 1.23 0.842 79 717 exclusion phecode
145.4 Cancer of the gums Neoplasms 1.35 0.994 – 1.84 0.0543 54 343 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.42 1.1 – 1.84 0.00765 75 363 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.21 1.08 – 1.35 0.00132 355 2312 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.33 1.07 – 1.65 0.00985 105 568 exclusion phecode
149.2 Cancer of nasopharynx Neoplasms 1.31 0.872 – 1.96 0.194 33 211 exclusion phecode
149.3 Cancer of hypopharynx Neoplasms 1.42 0.948 – 2.14 0.0888 28 154 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.29 1.05 – 1.6 0.0164 102 636 exclusion phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 1.33 1.12 – 1.58 0.00133 148 971 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.07 0.815 – 1.42 0.613 60 466 exclusion phecode
150 Cancer of esophagus Neoplasms 1.43 1.17 – 1.76 0.000639 99 751 exclusion phecode
151 Cancer of stomach Neoplasms 1.23 0.997 – 1.51 0.0532 112 884 exclusion phecode
153 Colorectal cancer Neoplasms 1.13 1 – 1.28 0.047 307 2977 exclusion phecode
153.2 Colon cancer Neoplasms 1.14 0.989 – 1.31 0.0706 224 2327 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.08 0.929 – 1.27 0.305 194 1749 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.22 0.993 – 1.49 0.0583 109 958 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.16 0.9 – 1.48 0.257 72 634 exclusion phecode
157 Pancreatic cancer Neoplasms 1.18 0.964 – 1.44 0.11 119 943 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.07 0.954 – 1.2 0.25 366 3192 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.14 1.02 – 1.26 0.0207 398 3485 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.962 0.707 – 1.31 0.803 44 428 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.18 0.858 – 1.62 0.31 44 300 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.12 0.871 – 1.43 0.384 74 624 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.781 0.548 – 1.11 0.172 36 255 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.24 1.1 – 1.4 0.000488 327 2562 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.2 1.05 – 1.37 0.00904 254 2026 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 1.04 0.944 – 1.16 0.402 438 3720 exclusion phecode
170.1 Bone cancer Neoplasms 1.13 0.973 – 1.31 0.109 205 1645 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1.05 0.933 – 1.19 0.393 295 2650 exclusion phecode
172 Skin cancer Neoplasms 0.969 0.918 – 1.02 0.238 2005 7136 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.925 0.867 – 0.987 0.0191 1183 6208 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.919 0.845 – 1 0.0524 622 5040 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.962 0.908 – 1.02 0.181 1698 6245 exclusion phecode
172.21 Basal cell carcinoma Neoplasms 0.899 0.835 – 0.969 0.00525 900 4642 exclusion phecode
172.22 Squamous cell carcinoma Neoplasms 1.06 0.964 – 1.16 0.236 583 3196 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.903 0.806 – 1.01 0.0808 363 2293 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.925 0.839 – 1.02 0.121 472 3913 exclusion phecode
174 Breast cancer Neoplasms 0.906 0.841 – 0.977 0.0101 942 4018 exclusion phecode
174.1 Breast cancer [female] Neoplasms 0.903 0.836 – 0.974 0.00854 905 3840 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.906 0.839 – 0.979 0.0123 886 3818 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.885 0.674 – 1.16 0.382 65 592 exclusion phecode
175 Acquired absence of breast Neoplasms 0.897 0.792 – 1.02 0.0898 301 2272 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.02 0.925 – 1.14 0.641 442 3333 exclusion phecode
180.1 Cervical cancer Neoplasms 1.1 0.915 – 1.32 0.314 135 1295 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1 0.891 – 1.12 0.994 356 2584 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.934 0.766 – 1.14 0.504 105 1877 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.07 0.952 – 1.21 0.244 313 2979 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.999 0.841 – 1.19 0.988 151 1504 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.964 0.794 – 1.17 0.713 120 1139 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.22 1.03 – 1.46 0.0247 150 1531 exclusion phecode
185 Cancer of prostate Neoplasms 0.857 0.759 – 0.968 0.0127 399 1589 exclusion phecode
187 Cancer of other male genital organs Neoplasms 0.924 0.714 – 1.2 0.549 66 631 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.03 0.614 – 1.74 0.901 14 181 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.888 0.648 – 1.22 0.46 42 389 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.828 0.436 – 1.57 0.563 12 97 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.11 1.01 – 1.23 0.0286 474 4570 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.11 0.959 – 1.28 0.166 217 2783 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.1 0.939 – 1.29 0.237 179 2436 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.23 0.878 – 1.72 0.23 43 421 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.18 1.04 – 1.33 0.0102 307 2791 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.2 1.05 – 1.36 0.00572 290 2565 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.34 1.1 – 1.64 0.00452 116 1178 exclusion phecode
190 Cancer of eye Neoplasms 0.995 0.716 – 1.38 0.976 44 274 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.08 0.948 – 1.23 0.243 257 2389 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 1.02 0.878 – 1.2 0.756 189 1564 exclusion phecode
191.11 Cancer of brain Neoplasms 1.03 0.873 – 1.21 0.748 166 1311 exclusion phecode
193 Thyroid cancer Neoplasms 0.995 0.851 – 1.16 0.955 180 2295 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.2 0.985 – 1.46 0.0697 115 1361 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.03 0.989 – 1.08 0.139 3803 6337 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.03 0.985 – 1.08 0.194 3739 6336 exclusion phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1.27 1.12 – 1.45 0.000327 276 1686 exclusion phecode
196 Radiotherapy Neoplasms 1.02 0.93 – 1.12 0.681 560 3437 exclusion phecode
197 Chemotherapy Neoplasms 1.15 1.08 – 1.23 3.09e-05 1227 5333 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.13 1.05 – 1.2 0.000417 1285 5236 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.1 1.02 – 1.19 0.0193 840 4617 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.37 1.18 – 1.58 3.27e-05 218 1968 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.13 0.98 – 1.31 0.0918 220 1681 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.31 1.12 – 1.53 0.000622 193 1429 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.16 0.974 – 1.38 0.0979 154 1229 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.35 1.16 – 1.58 0.000176 188 1540 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.995 0.782 – 1.27 0.966 81 608 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.07 1 – 1.14 0.046 1222 6068 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.37 0.954 – 1.97 0.0884 30 219 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.12 0.981 – 1.28 0.0946 259 2376 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.09 0.807 – 1.47 0.581 43 384 exclusion phecode
201 Hodgkin's disease Neoplasms 1.51 1.12 – 2.05 0.00761 47 409 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.11 0.993 – 1.23 0.068 375 3286 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.08 0.961 – 1.22 0.193 318 2810 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.07 0.911 – 1.25 0.429 183 1510 exclusion phecode
202.22 Reticulosarcoma Neoplasms 1.25 0.881 – 1.77 0.211 36 352 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.13 0.801 – 1.6 0.481 38 319 exclusion phecode
204 Leukemia Neoplasms 1.03 0.867 – 1.22 0.739 153 1343 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 0.958 0.734 – 1.25 0.75 58 448 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.11 0.714 – 1.74 0.636 21 173 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.854 0.614 – 1.19 0.347 38 313 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.1 0.835 – 1.44 0.505 62 505 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 1.06 0.741 – 1.51 0.762 36 268 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.739 0.389 – 1.4 0.356 16 128 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.19 0.872 – 1.62 0.272 42 438 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1.02 0.967 – 1.07 0.505 2119 8346 exclusion phecode
209 Neuroendocrine tumors Neoplasms 1.11 0.802 – 1.53 0.535 41 515 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.998 0.906 – 1.1 0.962 499 4205 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.09 1.03 – 1.15 0.00207 1559 8697 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.18 1.07 – 1.31 0.00108 437 3952 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.01 0.907 – 1.12 0.896 415 3699 exclusion phecode
214 Lipoma Neoplasms 0.998 0.873 – 1.14 0.973 260 3192 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.952 0.805 – 1.12 0.56 160 2008 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.01 0.943 – 1.08 0.809 1012 9144 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.902 0.862 – 0.943 6.54e-06 2817 8094 exclusion phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 1.08 0.78 – 1.48 0.656 45 416 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.861 0.782 – 0.949 0.00258 502 3752 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.861 0.779 – 0.953 0.00385 464 3438 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.918 0.858 – 0.982 0.0133 1154 4797 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.894 0.808 – 0.988 0.0287 461 4411 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.907 0.843 – 0.977 0.00977 944 4715 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.929 0.807 – 1.07 0.305 226 2392 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.01 0.913 – 1.11 0.909 506 4088 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.793 0.68 – 0.925 0.00317 182 1720 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.08 0.957 – 1.22 0.215 326 2723 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.922 0.781 – 1.09 0.335 161 1399 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.882 0.736 – 1.06 0.172 134 1127 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.14 1.01 – 1.3 0.0374 275 2764 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.09 0.94 – 1.25 0.262 213 2174 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.3 1.01 – 1.67 0.0434 71 639 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.994 0.873 – 1.13 0.925 259 3226 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.01 0.892 – 1.14 0.878 283 3878 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.25 0.967 – 1.6 0.0886 63 965 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.936 0.79 – 1.11 0.447 157 1863 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.959 0.745 – 1.23 0.745 63 1012 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.871 0.794 – 0.956 0.00369 538 4535 exclusion phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.822 0.734 – 0.922 0.000787 355 2832 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.988 0.936 – 1.04 0.668 1669 8554 exclusion phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 1 0.944 – 1.07 0.893 1210 7778 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.12 0.972 – 1.29 0.116 219 2530 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.04 0.957 – 1.14 0.329 605 5567 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1 0.908 – 1.11 0.968 475 4945 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.02 0.891 – 1.18 0.735 236 3181 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.04 0.92 – 1.17 0.54 299 3335 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.923 0.758 – 1.12 0.42 118 1249 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 0.938 0.599 – 1.47 0.78 19 307 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.959 0.754 – 1.22 0.735 72 698 exclusion phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.975 0.703 – 1.35 0.881 38 356 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.03 0.976 – 1.09 0.258 1647 7677 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.934 0.834 – 1.05 0.238 351 4262 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.03 0.908 – 1.16 0.678 284 3037 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.03 0.971 – 1.09 0.328 1538 7562 exclusion phecode
245 Thyroiditis Endocrine/metabolic 1.13 0.961 – 1.33 0.141 178 2110 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.17 0.981 – 1.4 0.0797 138 1770 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.18 0.985 – 1.41 0.0733 137 1751 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.02 0.954 – 1.08 0.617 1301 7120 exclusion phecode
246.2 Thyroid cyst Endocrine/metabolic 0.874 0.59 – 1.29 0.502 25 228 exclusion phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1.05 0.909 – 1.21 0.514 218 2156 exclusion phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.23 1.02 – 1.48 0.0276 169 1894 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.11 1.04 – 1.17 0.000621 1798 8752 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.21 1.05 – 1.41 0.0102 469 2920 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.89 1.27 – 2.82 0.00171 103 226 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.21 0.942 – 1.55 0.138 154 616 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.34 1.04 – 1.73 0.0215 189 705 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.36 1.06 – 1.74 0.0152 160 588 exclusion phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 1.22 0.822 – 1.8 0.328 49 173 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.14 1.05 – 1.22 0.000972 1078 7827 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.88 1.24 – 2.84 0.00283 77 288 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.31 1.09 – 1.57 0.00323 173 3130 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.24 1.03 – 1.51 0.0264 207 2284 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.19 1 – 1.41 0.0499 215 3893 exclusion phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.13 0.875 – 1.46 0.348 71 1331 exclusion phecode
250.3 Insulin pump user Endocrine/metabolic 1.18 1.04 – 1.35 0.0134 438 5081 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.09 1.02 – 1.17 0.0158 1238 8248 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.02 0.879 – 1.18 0.817 232 4125 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.09 1.01 – 1.17 0.0187 1125 7996 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.53 0.994 – 2.37 0.0531 26 290 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.25 1.03 – 1.51 0.023 205 3102 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.16 1.01 – 1.35 0.0418 256 2093 exclusion phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.1 0.962 – 1.26 0.164 245 1974 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.17 1.01 – 1.35 0.0303 310 2348 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.08 0.976 – 1.19 0.14 477 5165 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.04 0.94 – 1.15 0.437 435 4715 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.18 0.951 – 1.45 0.135 98 1179 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.03 0.878 – 1.22 0.698 164 1895 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.05 0.781 – 1.42 0.739 48 670 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.585 0.319 – 1.08 0.0842 11 203 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.83 0.59 – 1.17 0.285 32 477 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.58 0.925 – 2.69 0.0944 15 182 exclusion phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 0.853 0.519 – 1.4 0.529 18 220 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.43 0.959 – 2.13 0.0793 30 242 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.16 1.03 – 1.32 0.0188 276 3379 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.86 0.658 – 1.12 0.271 56 924 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.569 0.382 – 0.848 0.00559 26 495 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.4 0.83 – 2.36 0.207 15 281 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.09 0.908 – 1.32 0.348 131 1432 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.11 0.916 – 1.34 0.295 123 1361 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.856 0.748 – 0.981 0.0255 237 3240 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.747 0.592 – 0.944 0.0145 78 2257 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 0.961 0.801 – 1.15 0.669 127 1530 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.96 0.798 – 1.16 0.666 122 1469 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.22 0.754 – 1.99 0.413 17 186 exclusion phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.901 0.623 – 1.3 0.581 31 330 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 1.04 0.894 – 1.21 0.62 201 2439 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.24 1.15 – 1.33 2.4e-09 988 5553 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.39 1.15 – 1.69 0.000791 147 559 exclusion phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.38 1.26 – 1.52 3.1e-12 600 3325 exclusion phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.35 1.16 – 1.57 0.000126 214 1201 exclusion phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.32 1.13 – 1.55 0.000484 210 1199 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.37 1.2 – 1.57 4.32e-06 264 1878 exclusion phecode
260.7 Polyphagia Endocrine/metabolic 0.906 0.51 – 1.61 0.736 16 167 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.12 1.06 – 1.19 5.07e-05 1599 8182 exclusion phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1.35 0.902 – 2.03 0.144 22 160 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.34 1.14 – 1.57 0.000365 175 1833 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.11 1.05 – 1.18 0.000277 1500 8199 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.1 0.611 – 1.98 0.751 14 118 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.21 1.07 – 1.38 0.00337 269 2874 exclusion phecode
263 Other nutritional deficiency Endocrine/metabolic 1.11 0.994 – 1.24 0.0646 368 3637 exclusion phecode
264 Lack of normal physiological development Endocrine/metabolic 1 0.809 – 1.24 0.985 103 699 exclusion phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.09 0.809 – 1.46 0.583 51 309 exclusion phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 0.968 0.688 – 1.36 0.85 38 286 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.31 1.16 – 1.49 2.65e-05 286 3036 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.17 1.01 – 1.36 0.0412 201 2098 exclusion phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.955 0.667 – 1.37 0.801 34 418 exclusion phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.949 0.641 – 1.4 0.791 29 348 exclusion phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 1.37 0.762 – 2.46 0.293 10 223 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.23 1.03 – 1.46 0.0194 164 1518 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.21 0.935 – 1.57 0.148 72 737 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 0.875 0.542 – 1.41 0.584 19 142 exclusion phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 0.979 0.574 – 1.67 0.938 18 134 exclusion phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.33 1.04 – 1.7 0.0244 76 663 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.04 0.937 – 1.15 0.475 417 6296 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.01 0.905 – 1.12 0.913 394 6130 exclusion phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.51 1.02 – 2.25 0.0416 26 230 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.03 0.976 – 1.08 0.314 2862 7532 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.03 0.977 – 1.08 0.305 2851 7518 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.97 0.898 – 1.05 0.428 885 5677 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.961 0.794 – 1.16 0.68 112 2933 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.997 0.896 – 1.11 0.956 426 4669 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.82 0.623 – 1.08 0.155 61 737 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.08 0.95 – 1.22 0.249 266 4357 exclusion phecode
274.1 Gout Endocrine/metabolic 1.12 0.977 – 1.28 0.106 232 4169 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.07 0.879 – 1.3 0.51 106 2021 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.884 0.645 – 1.21 0.442 44 379 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.898 0.65 – 1.24 0.516 43 358 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.17 1.09 – 1.26 7.23e-06 945 8233 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.958 0.658 – 1.39 0.821 27 469 exclusion phecode
275.11 Hereditary hemochromatosis Hematopoietic 0.858 0.415 – 1.78 0.681 7 203 exclusion phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 1.37 0.805 – 2.32 0.247 15 153 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.32 1.16 – 1.51 2.51e-05 273 2426 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.14 1.05 – 1.23 0.00118 738 7005 exclusion phecode
275.51 Hypocalcemia Endocrine/metabolic 1.35 1.17 – 1.57 6.36e-05 218 1971 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.23 1.09 – 1.39 0.000813 320 2783 exclusion phecode
275.6 Hypercalcemia Endocrine/metabolic 1.12 0.989 – 1.27 0.074 290 3120 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.22 1.16 – 1.29 6.55e-15 2041 8801 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.27 1.2 – 1.35 7.2e-15 1364 7723 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.2 0.989 – 1.45 0.0642 127 1035 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.31 1.2 – 1.43 1.34e-09 637 4587 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.35 1.24 – 1.48 1.96e-11 600 5079 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.29 1.16 – 1.43 9.67e-07 444 4590 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.28 1.15 – 1.42 2.42e-06 443 4136 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.3 1.16 – 1.46 4.08e-06 371 3556 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.44 1.18 – 1.75 0.000357 124 982 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.25 1.17 – 1.34 9.04e-12 1141 7954 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.6 1.39 – 1.85 8.54e-11 239 2587 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.19 0.794 – 1.8 0.394 24 289 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.09 1 – 1.18 0.0375 701 8379 exclusion phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.61 1.12 – 2.32 0.0104 28 771 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.983 0.833 – 1.16 0.835 161 1518 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.05 0.883 – 1.25 0.581 143 2051 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.06 0.872 – 1.29 0.551 109 1709 exclusion phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.56 1.01 – 2.39 0.0433 17 1926 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.21 1.12 – 1.32 2.61e-06 678 10325 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.39 1.2 – 1.62 1.75e-05 177 10321 exclusion phecode
278.11 Morbid obesity Endocrine/metabolic 1.79 1.32 – 2.42 0.000158 40 10260 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 1.26 0.883 – 1.79 0.204 31 1298 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.15 1.02 – 1.29 0.0204 307 7284 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.16 1.08 – 1.25 0.000106 806 6578 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.22 1.08 – 1.37 0.00127 328 2565 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.25 0.994 – 1.57 0.0558 93 720 exclusion phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 1.06 0.912 – 1.24 0.427 198 1809 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.03 0.968 – 1.1 0.328 1119 8305 exclusion phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 1.07 0.909 – 1.27 0.403 171 1473 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.19 1.11 – 1.28 2.74e-07 1078 7054 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.2 1.12 – 1.29 8.95e-08 1043 7020 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.17 1.05 – 1.3 0.00368 408 3775 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.38 1.12 – 1.68 0.00201 116 1161 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.25 0.947 – 1.64 0.115 62 579 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.45 0.927 – 2.28 0.103 28 267 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.14 0.813 – 1.59 0.453 43 434 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.45 1.1 – 1.89 0.00773 63 652 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.15 0.895 – 1.47 0.277 69 693 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.05 0.776 – 1.43 0.739 46 437 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.28 0.93 – 1.76 0.13 38 411 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.48 1.04 – 2.11 0.0307 33 345 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.07 0.652 – 1.77 0.778 15 152 exclusion phecode
284 Aplastic anemia Hematopoietic 1.33 1.13 – 1.57 0.000531 181 1365 exclusion phecode
284.1 Pancytopenia Hematopoietic 1.37 1.15 – 1.64 0.000406 157 1208 exclusion phecode
285 Other anemias Hematopoietic 1.18 1.13 – 1.24 7.07e-13 2829 7835 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.23 1.14 – 1.33 1.63e-07 806 5912 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.38 1.25 – 1.52 4.36e-11 523 4091 exclusion phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.42 1.23 – 1.64 1.44e-06 221 1743 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.27 1.08 – 1.5 0.00344 182 1437 exclusion phecode
286 Coagulation defects Hematopoietic 1.13 1.04 – 1.22 0.0021 767 7586 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.809 0.597 – 1.1 0.172 50 594 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.797 0.491 – 1.29 0.357 20 197 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.9 0.59 – 1.37 0.624 22 307 exclusion phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.11 1.01 – 1.21 0.0285 550 5391 exclusion phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 1.14 0.773 – 1.69 0.5 34 325 exclusion phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 1.09 0.821 – 1.44 0.558 50 500 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.06 0.741 – 1.53 0.736 24 279 exclusion phecode
286.6 Defibrination syndrome Hematopoietic 1.14 1.04 – 1.25 0.00751 491 5592 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.11 1.02 – 1.21 0.0176 588 6545 exclusion phecode
286.8 Hypercoagulable state Hematopoietic 1.15 0.97 – 1.35 0.11 158 1963 exclusion phecode
286.81 Primary hypercoagulable state Hematopoietic 1.15 0.973 – 1.37 0.1 150 1863 exclusion phecode
286.9 Abnormal coagulation profile Hematopoietic 1.36 1.17 – 1.56 3.19e-05 224 2405 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.12 1.04 – 1.22 0.00318 740 6201 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.754 0.569 – 0.999 0.0495 55 491 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.16 1.06 – 1.26 0.000561 671 5659 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.19 0.981 – 1.45 0.0773 119 1303 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.23 1.02 – 1.49 0.0305 135 1209 exclusion phecode
287.4 Qualitative platelet defects Hematopoietic 1.13 0.753 – 1.69 0.56 23 267 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.15 1.08 – 1.22 1.96e-05 1201 8361 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.13 1.03 – 1.24 0.0112 515 3506 exclusion phecode
288.11 Neutropenia Hematopoietic 1.2 1.07 – 1.35 0.00191 341 2383 exclusion phecode
288.2 Elevated white blood cell count Hematopoietic 1.15 1.07 – 1.23 9.01e-05 962 7794 exclusion phecode
288.3 Eosinophilia Hematopoietic 1.02 0.736 – 1.41 0.909 46 411 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.19 1.08 – 1.32 0.000809 440 3991 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.12 0.97 – 1.29 0.123 232 2168 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.07 0.997 – 1.14 0.0618 946 7908 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1.21 0.964 – 1.52 0.1 79 834 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.36 0.974 – 1.91 0.0711 40 463 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.45 1.16 – 1.81 0.00107 99 843 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.21 1.08 – 1.37 0.00165 326 2192 exclusion phecode
290.1 Dementias Mental Disorders 0.968 0.797 – 1.17 0.74 116 945 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.983 0.668 – 1.45 0.93 32 269 exclusion phecode
290.12 Dementia with cerebral degenerations Mental Disorders 0.913 0.535 – 1.56 0.737 15 151 exclusion phecode
290.13 Senile dementia Mental Disorders 0.93 0.73 – 1.18 0.553 75 604 exclusion phecode
290.16 Vascular dementia Mental Disorders 1.22 0.753 – 1.96 0.424 20 144 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.33 1.13 – 1.55 0.000397 200 1357 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.04 0.901 – 1.21 0.577 208 1877 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.11 1.01 – 1.21 0.0284 540 5706 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.672 0.478 – 0.944 0.0219 36 500 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.18 0.977 – 1.42 0.0865 135 1160 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.13 1.02 – 1.25 0.0238 404 4403 exclusion phecode
292 Neurological disorders Mental Disorders 1.08 1.01 – 1.14 0.0153 1340 8914 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.07 0.976 – 1.18 0.144 514 4104 exclusion phecode
292.11 Aphasia Mental Disorders 1 0.846 – 1.18 1 158 1414 exclusion phecode
292.12 Symbolic dysfunction Mental Disorders 0.828 0.616 – 1.11 0.212 45 448 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 1.06 0.851 – 1.33 0.587 83 779 exclusion phecode
292.3 Memory loss Mental Disorders 0.894 0.803 – 0.995 0.0409 394 3874 exclusion phecode
292.4 Altered mental status Mental Disorders 1.27 1.16 – 1.39 3.83e-07 544 4644 exclusion phecode
292.5 Transient alteration of awareness Mental Disorders 1.09 0.888 – 1.33 0.414 105 944 exclusion phecode
292.6 Hallucinations Mental Disorders 1.3 0.943 – 1.79 0.109 50 472 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.17 0.945 – 1.45 0.149 109 942 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.07 0.999 – 1.14 0.0536 1033 8730 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.23 1.06 – 1.42 0.00621 211 1890 exclusion phecode
295.1 Schizophrenia Mental Disorders 0.946 0.654 – 1.37 0.768 30 327 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.17 0.759 – 1.79 0.482 24 252 exclusion phecode
295.3 Psychosis Mental Disorders 1.3 1.11 – 1.53 0.00145 175 1527 exclusion phecode
296 Mood disorders Mental Disorders 1.06 1.01 – 1.11 0.0119 3358 5135 exclusion phecode
296.1 Bipolar Mental Disorders 1.13 0.992 – 1.28 0.0667 288 3055 exclusion phecode
296.2 Depression Mental Disorders 1.06 1.01 – 1.11 0.0151 3217 5134 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.06 1.02 – 1.12 0.00999 2978 5134 exclusion phecode
297 Suicidal ideation or attempt Mental Disorders 1.17 1.03 – 1.33 0.0185 273 2462 exclusion phecode
297.1 Suicidal ideation Mental Disorders 1.1 0.951 – 1.27 0.2 211 2001 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.14 0.918 – 1.42 0.235 99 768 exclusion phecode
300 Anxiety disorders Mental Disorders 1.07 1.02 – 1.12 0.00373 3742 5135 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.08 1.03 – 1.13 0.00117 3556 5135 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 1.06 0.995 – 1.13 0.0709 1339 4978 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.02 0.898 – 1.15 0.806 330 3115 exclusion phecode
300.13 Phobia Mental Disorders 1.12 0.973 – 1.29 0.113 243 2450 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.836 0.659 – 1.06 0.139 75 881 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.09 0.991 – 1.19 0.0768 590 4164 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.04 0.84 – 1.3 0.7 103 1260 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.17 1 – 1.37 0.0489 192 2136 exclusion phecode
301 Personality disorders Mental Disorders 1.1 0.897 – 1.35 0.358 110 1340 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.09 0.833 – 1.42 0.531 64 700 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 0.978 0.89 – 1.07 0.635 544 2894 exclusion phecode
302.1 Decreased libido Mental Disorders 0.894 0.724 – 1.11 0.302 97 1003 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.907 0.853 – 0.964 0.00165 1620 4752 exclusion phecode
303.1 Dissociative disorder Mental Disorders 1.3 0.897 – 1.88 0.166 32 423 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.904 0.849 – 0.961 0.00136 1550 4697 exclusion phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.737 0.602 – 0.903 0.00325 120 1144 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.899 0.794 – 1.02 0.0953 312 3000 exclusion phecode
304 Adjustment reaction Mental Disorders 1.05 0.973 – 1.13 0.216 930 4959 exclusion phecode
305.2 Eating disorder Mental Disorders 1.16 0.974 – 1.38 0.0952 145 2340 exclusion phecode
306 Other mental disorder Mental Disorders 0.974 0.88 – 1.08 0.608 464 3668 exclusion phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 0.978 0.819 – 1.17 0.809 156 1234 exclusion phecode
306.9 Tension headache Mental Disorders 0.899 0.769 – 1.05 0.18 189 2011 exclusion phecode
312 Conduct disorders Mental Disorders 1.14 0.888 – 1.47 0.298 74 661 exclusion phecode
312.3 Impulse control disorder Mental Disorders 0.917 0.592 – 1.42 0.698 23 218 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 1.06 0.957 – 1.17 0.274 467 4203 exclusion phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1.04 0.937 – 1.15 0.476 423 3835 exclusion phecode
313.2 Tics and stuttering Mental Disorders 1.28 0.818 – 2.01 0.279 23 217 exclusion phecode
313.3 Autism Mental Disorders 1.2 0.654 – 2.21 0.553 12 202 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.11 0.939 – 1.32 0.216 167 1581 exclusion phecode
315.1 Learning disorder Mental Disorders 0.795 0.531 – 1.19 0.265 25 273 exclusion phecode
315.2 Speech and language disorder Mental Disorders 1.03 0.776 – 1.36 0.859 62 604 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.32 1.23 – 1.42 4.54e-15 963 7539 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.14 0.962 – 1.36 0.129 153 1360 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.14 1.05 – 1.24 0.00169 671 4789 exclusion phecode
317.1 Alcoholism Mental Disorders 1.16 1.06 – 1.27 0.00139 561 3801 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.28 1.01 – 1.63 0.044 81 651 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.34 1.27 – 1.41 5.4e-28 2004 8160 exclusion phecode
320 Meningitis Neurological 1.14 0.918 – 1.41 0.24 101 872 exclusion phecode
323 Encephalitis Neurological 1.41 1.03 – 1.94 0.0318 45 392 exclusion phecode
323.8 Encephalitis, non-infectious Neurological 1.41 0.998 – 2 0.0512 39 330 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.03 0.779 – 1.37 0.83 52 626 exclusion phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 0.672 0.362 – 1.25 0.207 10 118 exclusion phecode
327 Sleep disorders Neurological 1.03 0.981 – 1.08 0.236 2171 8803 exclusion phecode
327.1 Hypersomnia Neurological 0.953 0.841 – 1.08 0.457 266 5126 exclusion phecode
327.3 Sleep apnea Neurological 1.01 0.941 – 1.08 0.774 898 8640 exclusion phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1.01 0.807 – 1.26 0.947 81 1103 exclusion phecode
327.32 Obstructive sleep apnea Neurological 0.972 0.895 – 1.06 0.499 639 8241 exclusion phecode
327.4 Insomnia Neurological 1.04 0.979 – 1.11 0.194 1270 8485 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.06 0.935 – 1.2 0.368 286 3274 exclusion phecode
327.5 Parasomnia Neurological 0.859 0.684 – 1.08 0.189 74 1455 exclusion phecode
327.6 Circadian rhythm sleep disorder Neurological 0.911 0.692 – 1.2 0.509 54 740 exclusion phecode
327.7 Sleep related movement disorders Neurological 1.03 0.915 – 1.16 0.62 304 4527 exclusion phecode
327.71 Restless legs syndrome Neurological 1.04 0.913 – 1.18 0.574 263 4037 exclusion phecode
327.72 Sleep related leg cramps Neurological 1.1 0.683 – 1.78 0.692 18 181 exclusion phecode
331 Other cerebral degenerations Neurological 1.15 0.978 – 1.36 0.0906 175 1452 exclusion phecode
331.1 Hydrocephalus Neurological 1.08 0.845 – 1.39 0.53 69 663 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.19 0.964 – 1.47 0.106 105 817 exclusion phecode
332 Parkinson's disease Neurological 0.976 0.793 – 1.2 0.82 99 706 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.06 0.975 – 1.16 0.171 607 5909 exclusion phecode
333.1 Essential tremor Neurological 1.04 0.884 – 1.23 0.631 163 1443 exclusion phecode
333.2 Myoclonus Neurological 1.2 0.854 – 1.7 0.288 39 365 exclusion phecode
333.4 Torsion dystonia Neurological 0.998 0.816 – 1.22 0.981 113 785 exclusion phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 0.793 0.518 – 1.22 0.287 29 168 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.06 0.918 – 1.22 0.437 223 2251 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.19 0.759 – 1.87 0.444 21 164 exclusion phecode
334.2 Anterior horn cell disease Neurological 0.969 0.644 – 1.46 0.881 25 213 exclusion phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 1.22 0.7 – 2.12 0.485 17 119 exclusion phecode
335 Multiple sclerosis Neurological 1.13 0.912 – 1.4 0.259 101 931 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.09 0.935 – 1.26 0.282 203 1628 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.48 1.15 – 1.9 0.00247 73 560 exclusion phecode
338 Pain Neurological 1.1 1.06 – 1.15 1.81e-06 4506 6507 exclusion phecode
338.1 Acute pain Neurological 1.11 1.07 – 1.16 7.22e-07 3556 6458 exclusion phecode
338.2 Chronic pain Neurological 1.11 1.05 – 1.16 8.39e-05 2162 6474 exclusion phecode
339 Other headache syndromes Neurological 1.03 0.981 – 1.08 0.23 2155 8099 exclusion phecode
340 Migraine Neurological 1.01 0.96 – 1.07 0.608 1690 7395 exclusion phecode
340.1 Migrain with aura Neurological 1.07 0.99 – 1.15 0.09 915 6012 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.21 0.852 – 1.73 0.284 34 302 exclusion phecode
342 Hemiplegia Neurological 1.2 0.982 – 1.46 0.075 110 966 exclusion phecode
343 Infantile cerebral palsy Neurological 1.28 0.85 – 1.94 0.236 25 246 exclusion phecode
344 Other paralytic syndromes Neurological 1.19 1 – 1.4 0.0436 171 1436 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.05 0.967 – 1.14 0.242 654 5981 exclusion phecode
345.1 Epilepsy Neurological 1.05 0.901 – 1.22 0.552 194 1787 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.01 0.768 – 1.32 0.968 57 582 exclusion phecode
345.12 Partial epilepsy Neurological 1.02 0.849 – 1.22 0.862 138 1235 exclusion phecode
345.3 Convulsions Neurological 1.06 0.971 – 1.15 0.204 620 5634 exclusion phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.972 0.702 – 1.35 0.862 40 423 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.04 0.93 – 1.17 0.463 338 3127 exclusion phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.907 0.617 – 1.33 0.619 28 262 exclusion phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 1.07 0.697 – 1.66 0.745 19 257 exclusion phecode
347 Cataplexy and narcolepsy Neurological 0.853 0.541 – 1.35 0.494 20 250 exclusion phecode
348 Other conditions of brain Neurological 1.12 1.01 – 1.24 0.0357 425 4047 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.07 0.924 – 1.23 0.383 215 2071 exclusion phecode
348.4 Cerebral cysts Neurological 0.764 0.576 – 1.01 0.0624 53 566 exclusion phecode
348.7 Coma Neurological 1.09 0.826 – 1.43 0.549 57 529 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.34 1.14 – 1.56 0.000275 195 1750 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.06 0.97 – 1.16 0.193 532 5180 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.2 1.04 – 1.38 0.0112 234 2163 exclusion phecode
350 Abnormal movement Neurological 1.05 0.991 – 1.11 0.101 1494 9072 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.06 0.976 – 1.14 0.175 750 6804 exclusion phecode
350.2 Abnormality of gait Neurological 1.04 0.963 – 1.12 0.331 815 6558 exclusion phecode
350.3 Lack of coordination Neurological 1.06 0.935 – 1.2 0.373 293 2332 exclusion phecode
350.5 Abnormal reflex Neurological 1.15 0.839 – 1.57 0.389 43 453 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.948 0.783 – 1.15 0.589 118 1103 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.05 0.987 – 1.11 0.129 1352 8345 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.02 0.92 – 1.14 0.665 379 4003 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.969 0.809 – 1.16 0.736 125 1317 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.08 0.915 – 1.27 0.372 161 1792 exclusion phecode
353 Nerve root and plexus disorders Neurological 1.05 0.973 – 1.13 0.22 843 7874 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.988 0.803 – 1.22 0.906 110 956 exclusion phecode
353.2 Nerve root lesions Neurological 1.82 1.1 – 2.99 0.0188 24 257 exclusion phecode
355 Complex regional/central pain syndrome Neurological 1.04 0.863 – 1.25 0.69 131 1290 exclusion phecode
355.1 Chronic pain syndrome Neurological 1.2 1.03 – 1.41 0.0193 181 1965 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.13 1.02 – 1.26 0.0219 395 4283 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.14 1.05 – 1.24 0.00244 623 6312 exclusion phecode
358 Myoneural disorders Neurological 1.11 0.97 – 1.27 0.129 248 2514 exclusion phecode
358.1 Myasthenia gravis Neurological 0.777 0.524 – 1.15 0.208 26 245 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.969 0.859 – 1.09 0.605 309 2559 exclusion phecode
359.1 Muscular dystrophies Neurological 1.15 0.721 – 1.84 0.557 22 153 exclusion phecode
359.2 Myopathy Neurological 0.957 0.847 – 1.08 0.48 294 2454 exclusion phecode
360 Disorders of the globe Sense Organs 0.757 0.51 – 1.13 0.169 30 266 exclusion phecode
360.2 Progressive myopia Sense Organs 0.71 0.42 – 1.2 0.202 19 128 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.996 0.846 – 1.17 0.965 156 1427 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.83 0.643 – 1.07 0.152 65 551 exclusion phecode
362 Other retinal disorders Sense Organs 1.02 0.936 – 1.1 0.712 747 4729 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.964 0.869 – 1.07 0.487 450 3086 exclusion phecode
362.21 Macular degeneration, dry Sense Organs 0.941 0.744 – 1.19 0.616 89 722 exclusion phecode
362.22 Macular degeneration, wet Sense Organs 0.757 0.513 – 1.12 0.16 34 253 exclusion phecode
362.23 Cystoid macular degeneration of retina Sense Organs 0.974 0.78 – 1.22 0.818 88 800 exclusion phecode
362.26 Macular puckering of retina Sense Organs 0.966 0.82 – 1.14 0.681 173 1667 exclusion phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.968 0.79 – 1.19 0.75 114 930 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.959 0.86 – 1.07 0.458 403 2769 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.06 0.905 – 1.24 0.47 174 1727 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1.18 0.951 – 1.47 0.133 87 771 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.01 0.844 – 1.21 0.924 134 1199 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.97 0.779 – 1.21 0.784 97 793 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.34 1 – 1.78 0.0469 50 491 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.09 0.821 – 1.44 0.558 62 476 exclusion phecode
362.9 Retinal edema Sense Organs 0.993 0.757 – 1.3 0.959 59 565 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.929 0.762 – 1.13 0.466 114 962 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.832 0.654 – 1.06 0.135 73 644 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.954 0.84 – 1.08 0.462 283 2369 exclusion phecode
364.1 Corneal opacity Sense Organs 0.872 0.709 – 1.07 0.194 104 821 exclusion phecode
364.2 Corneal edema Sense Organs 0.883 0.574 – 1.36 0.573 22 244 exclusion phecode
364.4 Corneal degenerations Sense Organs 0.936 0.771 – 1.14 0.504 118 907 exclusion phecode
364.41 Keratoconus Sense Organs 0.647 0.397 – 1.05 0.0804 21 155 exclusion phecode
364.5 Corneal dystrophy Sense Organs 1.06 0.862 – 1.3 0.592 106 998 exclusion phecode
364.51 Fuchs' dystrophy Sense Organs 1.14 0.874 – 1.5 0.329 60 530 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.549 0.319 – 0.948 0.0313 17 188 exclusion phecode
365 Glaucoma Sense Organs 0.926 0.845 – 1.01 0.0951 573 4343 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 0.928 0.785 – 1.1 0.386 166 1308 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.793 0.627 – 1 0.0538 93 729 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.953 0.734 – 1.24 0.72 67 484 exclusion phecode
366 Cataract Sense Organs 0.982 0.925 – 1.04 0.548 1738 5909 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.74 0.555 – 0.987 0.0404 56 430 exclusion phecode
366.2 Senile cataract Sense Organs 0.944 0.879 – 1.01 0.115 1076 5140 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.943 0.897 – 0.992 0.0236 2073 8929 exclusion phecode
367.1 Myopia Sense Organs 0.909 0.854 – 0.968 0.00296 1236 8271 exclusion phecode
367.2 Astigmatism Sense Organs 0.918 0.856 – 0.985 0.0166 963 7507 exclusion phecode
367.8 Hypermetropia Sense Organs 0.905 0.819 – 1 0.0511 439 4193 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.06 0.931 – 1.2 0.399 276 2785 exclusion phecode
368 Visual disturbances Sense Organs 1.02 0.959 – 1.08 0.555 1304 9189 exclusion phecode
368.1 Amblyopia Sense Organs 1.03 0.86 – 1.22 0.777 142 1495 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.1 0.966 – 1.26 0.148 257 2306 exclusion phecode
368.3 Anisometropia Sense Organs 0.874 0.665 – 1.15 0.333 57 494 exclusion phecode
368.4 Visual field defects Sense Organs 0.993 0.859 – 1.15 0.922 202 2398 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.886 0.774 – 1.02 0.0813 246 2456 exclusion phecode
368.91 Psychophysical visual disturbances Sense Organs 1.06 0.735 – 1.54 0.743 30 248 exclusion phecode
369 Infection of the eye Sense Organs 0.965 0.893 – 1.04 0.364 768 6955 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.94 0.774 – 1.14 0.53 126 1209 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.96 0.882 – 1.04 0.341 653 6187 exclusion phecode
370 Keratitis Sense Organs 0.876 0.782 – 0.98 0.0211 363 3031 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.801 0.621 – 1.03 0.0866 73 497 exclusion phecode
370.2 Superficial keratitis Sense Organs 0.87 0.726 – 1.04 0.134 135 1226 exclusion phecode
370.3 Keratoconjunctivitis Sense Organs 1 0.85 – 1.19 0.966 170 1469 exclusion phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.839 0.621 – 1.13 0.252 51 429 exclusion phecode
371 Inflammation of the eye Sense Organs 0.942 0.881 – 1.01 0.0823 1061 7190 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.923 0.766 – 1.11 0.399 126 1173 exclusion phecode
371.2 Conjunctivitis, noninfectious Sense Organs 1.01 0.871 – 1.16 0.928 208 2101 exclusion phecode
371.21 Allergic conjunctivitis Sense Organs 0.986 0.839 – 1.16 0.861 171 1761 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.941 0.872 – 1.01 0.112 827 5881 exclusion phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 1.28 0.912 – 1.8 0.154 45 323 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.08 0.952 – 1.23 0.229 270 2280 exclusion phecode
374 Other disorders of eyelids Sense Organs 1 0.921 – 1.09 0.98 666 5197 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.922 0.749 – 1.14 0.449 104 867 exclusion phecode
374.2 Lagophthalmos Sense Organs 1.19 0.924 – 1.54 0.176 71 518 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 1.04 0.912 – 1.19 0.542 248 2311 exclusion phecode
374.6 Dermatochalasis Sense Organs 1.04 0.896 – 1.21 0.587 193 2010 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.945 0.878 – 1.02 0.134 897 5809 exclusion phecode
375.1 Dry eyes Sense Organs 0.961 0.895 – 1.03 0.281 970 5921 exclusion phecode
375.2 Epiphora Sense Organs 0.842 0.689 – 1.03 0.0924 109 943 exclusion phecode
376 Disorders of the orbit Sense Organs 1.1 0.883 – 1.37 0.395 85 816 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.984 0.848 – 1.14 0.836 187 2041 exclusion phecode
377.1 Optic atrophy Sense Organs 0.866 0.664 – 1.13 0.285 61 600 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.02 0.848 – 1.24 0.808 118 1325 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.06 0.939 – 1.19 0.355 308 2832 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.01 0.872 – 1.17 0.896 195 1886 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.19 0.878 – 1.62 0.26 44 362 exclusion phecode
378.5 Paralytic strabismus Sense Organs 0.896 0.706 – 1.14 0.366 83 745 exclusion phecode
379 Other disorders of eye Sense Organs 0.981 0.917 – 1.05 0.576 1109 6488 exclusion phecode
379.1 Scleritis and episcleritis Sense Organs 0.848 0.618 – 1.16 0.307 45 414 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.96 0.886 – 1.04 0.313 783 4805 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.898 0.626 – 1.29 0.56 38 278 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 0.996 0.768 – 1.29 0.973 62 614 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.977 0.759 – 1.26 0.857 73 591 exclusion phecode
379.51 Pigmentary iris degeneration Sense Organs 0.564 0.323 – 0.984 0.0439 18 138 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.964 0.847 – 1.1 0.584 268 2541 exclusion phecode
380 Disorders of external ear Sense Organs 0.934 0.851 – 1.02 0.149 533 4433 exclusion phecode
380.1 Otitis externa Sense Organs 0.83 0.734 – 0.939 0.00299 292 3392 exclusion phecode
380.4 Impacted cerumen Sense Organs 0.896 0.822 – 0.976 0.012 622 5170 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.985 0.92 – 1.05 0.659 984 8885 exclusion phecode
381.1 Otitis media Sense Organs 0.999 0.922 – 1.08 0.979 692 7540 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.01 0.924 – 1.1 0.83 570 6551 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.951 0.861 – 1.05 0.327 456 4389 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 1.06 0.74 – 1.53 0.737 30 367 exclusion phecode
381.9 Otorrhea Sense Organs 1.02 0.803 – 1.28 0.898 82 892 exclusion phecode
382 Otalgia Sense Organs 0.979 0.887 – 1.08 0.676 473 4795 exclusion phecode
383 Otosclerosis Sense Organs 1.17 0.817 – 1.67 0.395 33 289 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.01 0.836 – 1.22 0.905 126 1334 exclusion phecode
384.1 Myringitis Sense Organs 0.486 0.262 – 0.902 0.0222 13 126 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.06 0.856 – 1.31 0.603 100 1050 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.931 0.766 – 1.13 0.472 115 1063 exclusion phecode
385.3 Cholesteatoma Sense Organs 0.947 0.751 – 1.19 0.644 77 704 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.822 0.598 – 1.13 0.227 42 313 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.979 0.879 – 1.09 0.697 389 4144 exclusion phecode
386.1 Meniere's disease Sense Organs 0.88 0.683 – 1.13 0.321 69 699 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.956 0.848 – 1.08 0.462 313 3465 exclusion phecode
386.21 Central origin vertigo Sense Organs 0.934 0.814 – 1.07 0.334 239 2681 exclusion phecode
386.3 Labyrinthitis Sense Organs 0.971 0.86 – 1.1 0.635 305 3323 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.983 0.93 – 1.04 0.561 1533 8939 exclusion phecode
388 Other disorders of ear Sense Organs 0.951 0.828 – 1.09 0.474 235 2220 exclusion phecode
389 Hearing loss Sense Organs 0.967 0.917 – 1.02 0.223 1750 9108 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.919 0.854 – 0.989 0.0245 866 6253 exclusion phecode
389.2 Conductive hearing loss Sense Organs 0.977 0.852 – 1.12 0.734 231 2287 exclusion phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 1.04 0.735 – 1.46 0.844 45 353 exclusion phecode
389.4 Tinnitus Sense Organs 0.993 0.905 – 1.09 0.874 536 4740 exclusion phecode
389.5 Disorders of acoustic nerve Sense Organs 1.26 0.868 – 1.82 0.226 35 268 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.14 1.01 – 1.29 0.0377 313 2691 exclusion phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 1.02 0.792 – 1.31 0.89 71 628 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.08 0.872 – 1.34 0.475 103 958 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.15 0.761 – 1.74 0.505 25 304 exclusion phecode
394.4 Acute rheumatic heart disease Circulatory System 1.47 0.809 – 2.67 0.206 11 124 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.18 0.979 – 1.42 0.082 146 1151 exclusion phecode
395 Heart valve disorders Circulatory System 1.13 1.05 – 1.22 0.00111 885 6001 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.06 0.962 – 1.16 0.252 538 4304 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.29 1.15 – 1.44 1.04e-05 378 3214 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.09 0.894 – 1.33 0.391 121 1016 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.31 0.884 – 1.94 0.179 29 245 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.24 1.07 – 1.43 0.00519 205 2036 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.05 0.984 – 1.12 0.14 1089 7743 exclusion phecode
401 Hypertension Circulatory System 1.17 1.11 – 1.22 3.19e-10 3346 7626 exclusion phecode
401.1 Essential hypertension Circulatory System 1.16 1.11 – 1.22 8.21e-10 3302 7627 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.3 1.18 – 1.42 6.16e-08 559 4287 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.19 0.982 – 1.44 0.0758 115 1846 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.32 1.19 – 1.46 2.06e-07 433 3799 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.27 1.16 – 1.4 1.08e-06 489 4747 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.26 1.19 – 1.34 3.37e-13 1399 6875 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.08 0.888 – 1.31 0.449 114 1634 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.29 1.18 – 1.41 5.08e-08 581 4475 exclusion phecode
411.3 Angina pectoris Circulatory System 1.26 1.12 – 1.41 8.35e-05 351 3742 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.24 1.16 – 1.33 5.94e-10 1170 6026 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.24 0.783 – 1.96 0.362 22 310 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.26 1.17 – 1.36 1.3e-09 935 5489 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.2 0.947 – 1.53 0.13 78 862 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.18 1.08 – 1.3 0.000434 537 4888 exclusion phecode
414.2 ASCVD Circulatory System 1.13 0.919 – 1.38 0.253 105 1390 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.23 1.12 – 1.34 6.75e-06 568 6409 exclusion phecode
415.1 Acute pulmonary heart disease Circulatory System 1.17 1.04 – 1.32 0.0101 307 4016 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.16 1.03 – 1.31 0.0135 306 3996 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.31 1.16 – 1.47 8.18e-06 325 3624 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.37 1.14 – 1.66 0.000866 141 1459 exclusion phecode
416 Cardiomegaly Circulatory System 1.22 1.06 – 1.4 0.00701 223 2598 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.06 1.01 – 1.11 0.0159 2663 8303 exclusion phecode
418.1 Precordial pain Circulatory System 1.04 0.912 – 1.18 0.566 257 2916 exclusion phecode
420 Carditis Circulatory System 1.17 1.04 – 1.32 0.00901 325 3199 exclusion phecode
420.1 Myocarditis Circulatory System 0.859 0.531 – 1.39 0.537 16 212 exclusion phecode
420.2 Pericarditis Circulatory System 1.12 0.951 – 1.31 0.177 176 1693 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.16 0.831 – 1.62 0.381 43 368 exclusion phecode
420.22 Chronic pericarditis Circulatory System 0.931 0.589 – 1.47 0.759 21 235 exclusion phecode
420.3 Endocarditis Circulatory System 1.25 1.05 – 1.48 0.0102 162 1555 exclusion phecode
425 Cardiomyopathy Circulatory System 1.19 1.07 – 1.33 0.00165 365 3873 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.16 1.04 – 1.29 0.0101 347 3682 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.37 0.932 – 2.01 0.109 30 393 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.89 1.24 – 2.86 0.00281 26 421 exclusion phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.31 1.03 – 1.67 0.025 72 673 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.52 0.991 – 2.33 0.0551 24 212 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.09 1.03 – 1.14 0.0016 2393 6433 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.11 0.974 – 1.26 0.117 282 2269 exclusion phecode
426.21 First degree AV block Circulatory System 0.979 0.834 – 1.15 0.8 184 1698 exclusion phecode
426.22 Mobitz II AV block Circulatory System 1.23 0.652 – 2.34 0.518 11 121 exclusion phecode
426.23 Second degree AV block Circulatory System 1.15 0.829 – 1.59 0.404 41 380 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1.15 0.908 – 1.46 0.244 85 744 exclusion phecode
426.25 Other heart block Circulatory System 1.23 0.875 – 1.72 0.235 38 337 exclusion phecode
426.3 Bundle branch block Circulatory System 1.13 1.01 – 1.27 0.0264 378 2927 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.12 0.978 – 1.29 0.102 235 2178 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.14 0.957 – 1.35 0.144 152 1610 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.755 0.481 – 1.18 0.22 24 216 exclusion phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.09 1.04 – 1.15 0.00111 2072 6305 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.27 1.06 – 1.52 0.00947 137 1431 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.12 0.985 – 1.26 0.0838 305 2302 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.16 0.988 – 1.36 0.0697 189 1569 exclusion phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.19 0.999 – 1.41 0.0514 150 1374 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.03 0.991 – 1.08 0.118 3759 6569 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.05 0.956 – 1.15 0.307 517 4083 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.996 0.891 – 1.11 0.951 360 3264 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.15 0.996 – 1.33 0.0568 212 1952 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.08 0.996 – 1.17 0.063 880 4073 exclusion phecode
427.21 Atrial fibrillation Circulatory System 1.07 0.99 – 1.16 0.0841 850 3984 exclusion phecode
427.22 Atrial flutter Circulatory System 1.01 0.884 – 1.15 0.916 270 2103 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.05 0.993 – 1.11 0.0846 1873 6497 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.984 0.786 – 1.23 0.887 89 1045 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.09 0.748 – 1.58 0.661 31 405 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.02 0.803 – 1.31 0.85 76 797 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.01 0.949 – 1.07 0.777 1413 6465 exclusion phecode
427.6 Premature beats Circulatory System 0.904 0.816 – 1 0.0531 451 3494 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1.06 0.889 – 1.27 0.504 144 1322 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.11 1.04 – 1.18 0.00181 1198 6476 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.09 0.924 – 1.28 0.309 174 1536 exclusion phecode
427.9 Palpitations Circulatory System 0.927 0.866 – 0.992 0.029 1079 6085 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.29 1.18 – 1.4 4.27e-09 692 5011 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.29 1.18 – 1.41 4.49e-08 592 4695 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.32 1.2 – 1.45 3.93e-09 568 4489 exclusion phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.3 1.15 – 1.48 2.41e-05 312 2812 exclusion phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.38 1.18 – 1.6 3.13e-05 207 2667 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.05 1 – 1.1 0.0473 2642 8036 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.17 1.02 – 1.34 0.0236 243 2297 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.15 1.08 – 1.23 4.13e-05 1140 6729 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.03 0.981 – 1.08 0.221 2144 7990 exclusion phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.21 1.01 – 1.46 0.0431 123 1402 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.06 0.909 – 1.24 0.443 183 1622 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.1 0.827 – 1.46 0.515 60 542 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.08 0.862 – 1.34 0.515 87 759 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 0.997 0.781 – 1.27 0.983 73 525 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.1 1.03 – 1.17 0.0071 1116 6795 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.13 1.02 – 1.26 0.0222 418 3096 exclusion phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.13 0.86 – 1.49 0.377 60 505 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 0.921 0.548 – 1.55 0.758 16 154 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.14 1.03 – 1.26 0.00833 482 4311 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.14 1.03 – 1.26 0.00894 467 4173 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.05 0.958 – 1.15 0.295 558 4590 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.07 0.969 – 1.18 0.18 483 4143 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.14 0.937 – 1.39 0.189 123 1079 exclusion phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.08 0.854 – 1.36 0.523 76 904 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.12 0.938 – 1.33 0.211 139 1421 exclusion phecode
440 Atherosclerosis Circulatory System 1.17 1.06 – 1.29 0.00158 483 3834 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.916 0.695 – 1.21 0.531 53 473 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.13 1 – 1.28 0.0486 289 2602 exclusion phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.64 1.24 – 2.17 0.000571 57 444 exclusion phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.07 0.924 – 1.25 0.357 202 1833 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.22 1.02 – 1.45 0.0287 146 1519 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.14 0.952 – 1.36 0.154 141 1086 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.04 0.788 – 1.36 0.804 64 493 exclusion phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 0.93 0.695 – 1.25 0.627 49 341 exclusion phecode
442 Other aneurysm Circulatory System 1.17 1.07 – 1.29 0.000645 538 4204 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.21 1.08 – 1.35 0.00104 359 3044 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.14 0.987 – 1.31 0.0758 231 1842 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.12 0.75 – 1.68 0.572 26 331 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.06 0.716 – 1.57 0.769 26 317 exclusion phecode
442.4 Arterial dissection Circulatory System 0.829 0.602 – 1.14 0.251 41 360 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.14 0.91 – 1.43 0.253 97 829 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.09 1.01 – 1.18 0.0336 751 5181 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 0.997 0.876 – 1.13 0.96 299 1780 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.85 1.2 – 2.87 0.00566 25 321 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.09 1 – 1.19 0.0413 633 4524 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.15 1.04 – 1.27 0.00485 470 3653 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.11 0.961 – 1.29 0.154 205 1687 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.02 0.814 – 1.28 0.862 85 563 exclusion phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 0.868 0.593 – 1.27 0.467 33 254 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.1 0.907 – 1.34 0.328 112 996 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.93 0.636 – 1.36 0.71 29 233 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.09 0.668 – 1.78 0.73 17 155 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.05 0.823 – 1.34 0.699 74 611 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.11 1.02 – 1.22 0.0212 541 4593 exclusion phecode
447.1 Stricture of artery Circulatory System 1.2 0.994 – 1.44 0.0584 127 1103 exclusion phecode
447.7 Aortic ectasia Circulatory System 1.14 0.941 – 1.38 0.18 110 1448 exclusion phecode
448 Disease of capillaries Circulatory System 0.931 0.828 – 1.05 0.23 338 2641 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.1 0.994 – 1.22 0.066 431 4714 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.01 0.855 – 1.19 0.915 154 1664 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.945 0.681 – 1.31 0.733 39 565 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1.13 1.05 – 1.21 0.000628 915 7002 exclusion phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1.32 0.932 – 1.87 0.118 32 571 exclusion phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1.13 1.04 – 1.24 0.00421 596 6075 exclusion phecode
452.8 Postphlebitic syndrome Circulatory System 1.09 0.708 – 1.67 0.707 21 348 exclusion phecode
453 Chronic venous hypertension Circulatory System 1.03 0.762 – 1.39 0.85 47 476 exclusion phecode
454 Varicose veins Circulatory System 1.04 0.949 – 1.13 0.434 608 5675 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1.03 0.941 – 1.14 0.484 514 4894 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.02 0.901 – 1.14 0.802 316 3463 exclusion phecode
455 Hemorrhoids Circulatory System 0.959 0.901 – 1.02 0.181 1282 6964 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1 0.918 – 1.1 0.937 567 5684 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.05 0.938 – 1.17 0.406 364 3134 exclusion phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.14 0.861 – 1.5 0.368 55 598 exclusion phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.03 0.923 – 1.16 0.557 336 2996 exclusion phecode
458 Hypotension Circulatory System 1.24 1.17 – 1.33 3.8e-11 1176 7346 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.26 1.11 – 1.41 0.000192 332 2790 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.29 1.12 – 1.48 0.000264 240 2177 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.25 1.16 – 1.33 1.87e-10 1063 7007 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.15 1.08 – 1.22 3.42e-06 1488 8249 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.09 0.937 – 1.27 0.262 198 1796 exclusion phecode
459.7 Blood vessel replaced Circulatory System 1.25 1.09 – 1.42 0.00088 270 2697 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.14 1.07 – 1.21 6.37e-05 1216 7763 exclusion phecode
464 Acute sinusitis Respiratory 0.97 0.908 – 1.04 0.378 1058 7669 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.986 0.94 – 1.03 0.568 2314 8379 exclusion phecode
465.2 Acute pharyngitis Respiratory 0.962 0.906 – 1.02 0.203 1387 7845 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.02 0.825 – 1.27 0.838 99 1091 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.959 0.868 – 1.06 0.408 447 4242 exclusion phecode
471 Nasal polyps Respiratory 1 0.832 – 1.2 0.99 128 1347 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.931 0.837 – 1.04 0.193 386 4089 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.1 1.01 – 1.19 0.0205 765 5620 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.22 0.693 – 2.14 0.496 15 141 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.12 0.943 – 1.33 0.196 152 1442 exclusion phecode
473.4 Voice disturbance Respiratory 1.13 1.03 – 1.23 0.00731 621 4837 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1.02 0.899 – 1.15 0.774 289 2465 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.03 0.854 – 1.24 0.765 129 1165 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.992 0.861 – 1.14 0.912 220 2021 exclusion phecode
475 Chronic sinusitis Respiratory 1.02 0.95 – 1.09 0.61 987 6534 exclusion phecode
475.9 Postnasal drip Respiratory 0.97 0.835 – 1.13 0.695 196 1995 exclusion phecode
476 Allergic rhinitis Respiratory 0.954 0.912 – 0.998 0.0404 2895 6585 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.07 0.942 – 1.22 0.297 266 2574 exclusion phecode
478 Throat pain Respiratory 0.99 0.809 – 1.21 0.921 120 1024 exclusion phecode
479 Other upper respiratory disease Respiratory 1.05 0.987 – 1.12 0.121 1311 6567 exclusion phecode
480 Pneumonia Respiratory 1.14 1.08 – 1.21 1.5e-05 1287 8722 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.12 0.997 – 1.26 0.0554 309 2487 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.31 1.09 – 1.57 0.00361 139 1193 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.22 0.894 – 1.66 0.213 50 359 exclusion phecode
480.13 MRSA pneumonia Respiratory 1.27 0.802 – 2.01 0.309 20 272 exclusion phecode
480.2 Viral pneumonia Respiratory 1.39 0.996 – 1.94 0.0531 41 379 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.51 1.11 – 2.07 0.00972 47 332 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.29 0.897 – 1.86 0.169 39 297 exclusion phecode
481 Influenza Respiratory 1.07 0.944 – 1.21 0.298 298 3205 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.01 0.93 – 1.1 0.796 646 7069 exclusion phecode
495 Asthma Respiratory 1.07 1.01 – 1.13 0.0145 1770 8173 exclusion phecode
495.1 Chronic obstructive asthma Respiratory 1.49 1.15 – 1.94 0.00286 66 857 exclusion phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 1.39 0.615 – 3.15 0.427 8 159 exclusion phecode
495.2 Asthma with exacerbation Respiratory 0.971 0.863 – 1.09 0.625 321 4419 exclusion phecode
496 Chronic airway obstruction Respiratory 1.31 1.22 – 1.4 1.32e-15 1192 6161 exclusion phecode
496.1 Emphysema Respiratory 1.37 1.25 – 1.5 3.72e-11 559 3825 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.42 1.31 – 1.53 5.35e-19 840 5653 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.47 1.35 – 1.59 9.31e-21 770 5285 exclusion phecode
496.3 Bronchiectasis Respiratory 1.14 0.967 – 1.35 0.117 170 1143 exclusion phecode
497 Bronchitis Respiratory 1.08 0.971 – 1.21 0.152 365 4623 exclusion phecode
498 Acute bronchospasm Respiratory 1.27 1.03 – 1.58 0.0258 97 1271 exclusion phecode
499 Cystic fibrosis Respiratory 1.02 0.77 – 1.36 0.871 57 408 exclusion phecode
500 Lung disease due to external agents Respiratory 1.28 1.05 – 1.56 0.0143 122 1106 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.25 0.758 – 2.07 0.38 23 203 exclusion phecode
500.2 Pneumoconiosis Respiratory 1.06 0.512 – 2.2 0.872 10 121 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.39 1.17 – 1.64 0.000151 173 1183 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.15 0.972 – 1.35 0.105 165 1637 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.29 1.09 – 1.52 0.00299 164 1657 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.2 0.987 – 1.45 0.0679 126 1197 exclusion phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 1.18 0.901 – 1.55 0.229 66 623 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.2 1.07 – 1.35 0.00181 342 3215 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.2 1.11 – 1.3 9.17e-06 701 5222 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.21 1.11 – 1.31 9.99e-06 659 5524 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.23 1.11 – 1.35 3.38e-05 475 4713 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.21 1.12 – 1.31 6.64e-07 808 6265 exclusion phecode
509.1 Respiratory failure Respiratory 1.32 1.19 – 1.47 2.08e-07 427 3812 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.12 0.984 – 1.28 0.0855 269 2349 exclusion phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.2 1.08 – 1.34 0.000982 385 3241 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.29 1.15 – 1.46 3.12e-05 317 3416 exclusion phecode
510 Other diseases of lung Respiratory 1.1 1.03 – 1.17 0.00332 1194 7846 exclusion phecode
510.2 Lung transplant Respiratory 1.55 1.12 – 2.14 0.00806 51 373 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.11 1.07 – 1.16 5.47e-07 3890 7132 exclusion phecode
512.1 Wheezing Respiratory 1.32 1.15 – 1.52 0.000127 215 3292 exclusion phecode
512.2 Painful respiration Respiratory 1.12 1.02 – 1.22 0.0179 552 5258 exclusion phecode
512.3 Abnormal chest sounds Respiratory 1.28 0.986 – 1.65 0.0643 73 608 exclusion phecode
512.7 Shortness of breath Respiratory 1.14 1.08 – 1.2 8.91e-07 1926 7104 exclusion phecode
512.8 Cough Respiratory 1.09 1.04 – 1.15 0.000981 2033 7127 exclusion phecode
512.9 Other dyspnea Respiratory 1.11 1.06 – 1.17 4.41e-05 1997 7106 exclusion phecode
513 Respiratory abnormalities Respiratory 1.11 1.06 – 1.17 5.81e-06 2470 8537 exclusion phecode
513.3 Hypoventilation Respiratory 1.14 0.952 – 1.37 0.153 128 1878 exclusion phecode
513.31 Apnea Respiratory 1.13 0.883 – 1.44 0.337 76 960 exclusion phecode
513.32 Orthopnea Respiratory 1.13 0.768 – 1.65 0.545 28 412 exclusion phecode
513.4 Hyperventilation Respiratory 1.12 0.905 – 1.4 0.293 94 1120 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.45 1.04 – 2.02 0.0292 40 488 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.16 1.08 – 1.23 7.93e-06 1193 7434 exclusion phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 0.967 0.727 – 1.29 0.819 52 543 exclusion phecode
514.2 Solitary pulmonary nodule Respiratory 1.16 1.07 – 1.26 0.000531 652 5644 exclusion phecode
516 Abnormal sputum Respiratory 1.17 0.995 – 1.37 0.058 169 1494 exclusion phecode
516.1 Hemoptysis Respiratory 1.18 0.983 – 1.41 0.0761 137 1263 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.1 1.04 – 1.16 0.00168 1418 9074 exclusion phecode
519.1 Tracheostomy complications Respiratory 1.25 0.953 – 1.63 0.108 64 431 exclusion phecode
519.2 Respiratory complications Respiratory 1.01 0.814 – 1.25 0.931 94 928 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.04 0.934 – 1.16 0.475 382 3472 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.13 1.06 – 1.21 0.000322 1037 7618 exclusion phecode
520 Disorders of tooth development Digestive 1.07 0.883 – 1.3 0.487 120 952 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.34 0.993 – 1.81 0.0559 52 380 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 1.01 0.803 – 1.28 0.902 77 638 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.41 1.23 – 1.62 1e-06 250 1935 exclusion phecode
521.1 Dental caries Digestive 1.38 1.2 – 1.59 9.04e-06 234 1781 exclusion phecode
521.2 Dental abrasion, erosion and attrition Digestive 1.48 0.758 – 2.88 0.252 8 116 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.3 1.07 – 1.58 0.00889 111 1178 exclusion phecode
522.5 Periapical abscess Digestive 1.44 1.16 – 1.78 0.00081 95 1040 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.25 1.06 – 1.47 0.00859 163 1547 exclusion phecode
523.1 Gingivitis Digestive 1.08 0.782 – 1.5 0.627 38 340 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.6 1.24 – 2.05 0.000251 71 779 exclusion phecode
523.31 Acute periodontitis Digestive 1.47 1.12 – 1.92 0.00521 56 663 exclusion phecode
523.32 Chronic periodontitis Digestive 1.76 1.17 – 2.64 0.00658 30 246 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.981 0.818 – 1.18 0.833 160 1055 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.966 0.779 – 1.2 0.756 110 683 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.28 1.13 – 1.45 0.000145 278 2423 exclusion phecode
525.1 Loss of teeth or edentulism Digestive 1.3 1.06 – 1.6 0.012 105 894 exclusion phecode
526 Diseases of the jaws Digestive 1.02 0.95 – 1.1 0.532 817 6561 exclusion phecode
526.1 Cysts of the jaws Digestive 0.93 0.709 – 1.22 0.599 53 512 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.01 0.83 – 1.24 0.899 123 786 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 0.983 0.889 – 1.09 0.74 453 3884 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.969 0.867 – 1.08 0.574 371 3116 exclusion phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 1.03 0.894 – 1.18 0.707 237 2005 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 1.18 0.953 – 1.47 0.128 104 654 exclusion phecode
526.8 Exostosis of jaw Digestive 1.86 1.07 – 3.23 0.0279 21 98 exclusion phecode
526.9 Jaw disease NOS Digestive 1.12 0.954 – 1.32 0.161 173 1118 exclusion phecode
527 Diseases of the salivary glands Digestive 1.07 0.97 – 1.19 0.167 425 3834 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.27 0.703 – 2.29 0.43 14 141 exclusion phecode
527.2 Sialoadenitis Digestive 1.15 0.923 – 1.42 0.218 95 913 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.15 0.999 – 1.32 0.0521 226 1880 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 0.868 0.65 – 1.16 0.337 54 529 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.03 0.956 – 1.12 0.404 751 5899 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.09 0.938 – 1.27 0.263 200 1559 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.2 0.899 – 1.61 0.214 51 490 exclusion phecode
528.12 Oral aphthae Digestive 0.928 0.724 – 1.19 0.559 69 559 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.52 1.18 – 1.96 0.00115 74 528 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.719 0.497 – 1.04 0.0794 33 296 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.756 0.474 – 1.2 0.24 23 176 exclusion phecode
528.5 Diseases of lips Digestive 1 0.839 – 1.2 0.977 142 1063 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 0.952 0.67 – 1.35 0.782 34 277 exclusion phecode
528.7 Sialolithiasis Digestive 1.09 0.792 – 1.49 0.609 44 339 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.09 0.921 – 1.28 0.327 156 1409 exclusion phecode
529.1 Glossitis Digestive 1.16 0.802 – 1.67 0.434 30 268 exclusion phecode
529.6 Glossodynia Digestive 1.06 0.741 – 1.52 0.741 30 321 exclusion phecode
530 Diseases of esophagus Digestive 1.13 1.09 – 1.19 2.24e-08 3202 7330 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.13 1.08 – 1.18 7.58e-08 3046 7330 exclusion phecode
530.11 GERD Digestive 1.13 1.08 – 1.18 1.17e-07 2914 7329 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.22 0.976 – 1.53 0.0806 84 907 exclusion phecode
530.13 Barrett's esophagus Digestive 1.14 0.931 – 1.4 0.206 106 1472 exclusion phecode
530.14 Reflux esophagitis Digestive 1.15 1.03 – 1.28 0.0138 367 4224 exclusion phecode
530.15 Eosinophilic esophagitis Digestive 1.03 0.766 – 1.38 0.855 49 627 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.18 0.993 – 1.4 0.0601 137 1353 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1.12 0.969 – 1.29 0.124 217 2006 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.09 0.905 – 1.31 0.37 131 1344 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.03 0.73 – 1.44 0.886 43 257 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.7 1.09 – 2.65 0.0196 22 185 exclusion phecode
530.9 Heartburn Digestive 1.1 0.971 – 1.24 0.137 300 3782 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.14 1.03 – 1.26 0.0105 435 4455 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.2 0.947 – 1.51 0.133 81 733 exclusion phecode
531.2 Gastric ulcer Digestive 1.22 1.07 – 1.39 0.0038 247 2646 exclusion phecode
531.3 Duodenal ulcer Digestive 1.23 0.994 – 1.53 0.0566 99 883 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.07 0.914 – 1.26 0.389 180 1724 exclusion phecode
531.5 Gastrojejunal ulcer Digestive 1.14 0.827 – 1.58 0.422 38 323 exclusion phecode
532 Dysphagia Digestive 1.2 1.13 – 1.28 3.16e-09 1388 6859 exclusion phecode
535 Gastritis and duodenitis Digestive 1.07 0.983 – 1.17 0.116 611 6299 exclusion phecode
535.1 Acute gastritis Digestive 1.17 1.02 – 1.34 0.0216 238 2623 exclusion phecode
535.2 Atrophic gastritis Digestive 0.923 0.724 – 1.18 0.516 76 786 exclusion phecode
535.6 Duodenitis Digestive 1.04 0.817 – 1.32 0.753 67 710 exclusion phecode
535.8 Other specified gastritis Digestive 0.95 0.8 – 1.13 0.554 142 1439 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.05 0.933 – 1.19 0.402 294 2905 exclusion phecode
536 Disorders of function of stomach Digestive 1.12 1.04 – 1.21 0.004 771 6521 exclusion phecode
536.3 Gastroparesis Digestive 1.27 1.08 – 1.5 0.00342 184 1584 exclusion phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.22 1 – 1.48 0.0455 137 858 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.09 0.997 – 1.2 0.0572 544 4961 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.11 1.03 – 1.2 0.00936 746 6762 exclusion phecode
537.1 Lesions of stomach and duodenum Digestive 1.25 0.883 – 1.76 0.209 34 309 exclusion phecode
539 Bariatric surgery Digestive 2.15 1.69 – 2.73 4.02e-10 73 3739 exclusion phecode
540 Appendiceal conditions Digestive 0.837 0.693 – 1.01 0.0659 126 1222 exclusion phecode
540.1 Appendicitis Digestive 0.818 0.664 – 1.01 0.0573 110 1037 exclusion phecode
540.11 Acute appendicitis Digestive 0.79 0.631 – 0.989 0.0399 95 855 exclusion phecode
550 Abdominal hernia Digestive 1.02 0.961 – 1.09 0.486 1207 8816 exclusion phecode
550.1 Inguinal hernia Digestive 0.878 0.794 – 0.971 0.0112 445 3017 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.07 0.965 – 1.18 0.207 446 5737 exclusion phecode
550.3 Femoral hernia Digestive 0.808 0.576 – 1.13 0.215 51 272 exclusion phecode
550.4 Umbilical hernia Digestive 0.929 0.787 – 1.1 0.389 155 2658 exclusion phecode
550.5 Ventral hernia Digestive 1.14 1.02 – 1.28 0.0194 340 4744 exclusion phecode
550.6 Incisional hernia Digestive 1.21 1.04 – 1.41 0.0164 177 2826 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.14 1.03 – 1.26 0.00861 466 3704 exclusion phecode
555.1 Regional enteritis Digestive 1.25 1.11 – 1.41 0.00029 313 2269 exclusion phecode
555.2 Ulcerative colitis Digestive 1.02 0.894 – 1.16 0.776 273 2180 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 0.959 0.81 – 1.13 0.624 175 1300 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.1 0.933 – 1.29 0.257 159 1371 exclusion phecode
556.1 Ulceration of intestine Digestive 1.09 0.917 – 1.3 0.325 139 1217 exclusion phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 1.12 0.82 – 1.53 0.473 40 393 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.14 1.02 – 1.27 0.0172 381 4374 exclusion phecode
557.1 Celiac disease Digestive 1.09 0.914 – 1.3 0.337 155 1065 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.11 1.04 – 1.2 0.00373 893 6442 exclusion phecode
559 Ileostomy status Digestive 1.2 1.05 – 1.38 0.0073 248 2053 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.21 1.12 – 1.31 1.24e-06 792 5625 exclusion phecode
560.1 Paralytic ileus Digestive 1.16 1.04 – 1.29 0.00803 385 3274 exclusion phecode
560.2 Impaction of intestine Digestive 1.18 0.957 – 1.45 0.122 111 930 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.24 0.987 – 1.55 0.0645 90 613 exclusion phecode
560.4 Other intestinal obstruction Digestive 1.27 1.15 – 1.4 2.58e-06 482 3597 exclusion phecode
561 Symptoms involving digestive system Digestive 1.08 0.998 – 1.18 0.0564 672 5257 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1.05 0.975 – 1.13 0.202 1035 4936 exclusion phecode
562.1 Diverticulosis Digestive 1.04 0.97 – 1.12 0.26 1026 4925 exclusion phecode
562.2 Diverticulitis Digestive 1.18 1.03 – 1.34 0.0175 249 3143 exclusion phecode
564 Functional digestive disorders Digestive 1.12 1.07 – 1.17 2.43e-06 2747 6964 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.09 1.01 – 1.17 0.0206 904 5634 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.16 1.07 – 1.26 0.000418 685 5931 exclusion phecode
565 Anal and rectal conditions Digestive 1.03 0.956 – 1.11 0.435 818 6940 exclusion phecode
565.1 Anal and rectal polyp Digestive 0.982 0.856 – 1.13 0.791 236 2505 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.31 1.16 – 1.47 7.41e-06 336 2915 exclusion phecode
568 Other disorders of peritoneum Digestive 1.15 1.03 – 1.28 0.0109 372 3676 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.15 1.01 – 1.31 0.0331 262 2676 exclusion phecode
569 Other disorders of intestine Digestive 1.1 1.04 – 1.16 0.000798 1700 8326 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.26 0.994 – 1.6 0.056 81 697 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.24 1.1 – 1.4 0.000455 304 3101 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.14 1.05 – 1.23 0.00141 692 7454 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.13 1.04 – 1.23 0.00518 622 7333 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.23 1.05 – 1.43 0.00819 178 1964 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.34 0.966 – 1.86 0.0798 38 370 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.22 1.05 – 1.42 0.00762 201 1842 exclusion phecode
571.81 Portal hypertension Digestive 1.19 0.976 – 1.45 0.0853 106 1127 exclusion phecode
572 Ascites (non malignant) Digestive 1.17 1.07 – 1.28 0.000515 575 5073 exclusion phecode
573 Other disorders of liver Digestive 1.1 1.03 – 1.17 0.00648 1049 7805 exclusion phecode
573.1 Chronic passive congestion of liver Digestive 1.31 0.909 – 1.89 0.148 33 296 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.1 0.859 – 1.4 0.456 71 550 exclusion phecode
573.3 Hepatomegaly Digestive 1.38 1.12 – 1.7 0.00291 93 1082 exclusion phecode
573.4 Acute and subacute necrosis of liver Digestive 1.13 0.891 – 1.44 0.309 80 635 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.06 0.925 – 1.22 0.387 232 1937 exclusion phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.06 0.974 – 1.16 0.17 560 5842 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.12 1.02 – 1.22 0.0128 572 6092 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.09 1.02 – 1.17 0.0103 969 7954 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.08 0.987 – 1.19 0.0921 520 7209 exclusion phecode
574.1 Cholelithiasis Digestive 1.08 0.984 – 1.2 0.102 455 6806 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.932 0.697 – 1.25 0.632 46 772 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.03 0.812 – 1.3 0.821 77 1290 exclusion phecode
574.2 Calculus of bile duct Digestive 0.981 0.83 – 1.16 0.819 161 1979 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.14 0.949 – 1.36 0.166 137 1871 exclusion phecode
575 Other biliary tract disease Digestive 1.09 0.989 – 1.19 0.0835 496 5142 exclusion phecode
575.1 Cholangitis Digestive 1.08 0.878 – 1.33 0.471 101 731 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.09 0.923 – 1.28 0.322 173 1349 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.788 0.576 – 1.08 0.135 40 529 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.09 0.931 – 1.28 0.277 170 2192 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.12 0.989 – 1.26 0.0761 302 2508 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.925 0.694 – 1.23 0.593 56 590 exclusion phecode
577 Diseases of pancreas Digestive 1.13 1.03 – 1.23 0.0102 554 4716 exclusion phecode
577.1 Acute pancreatitis Digestive 1.2 1.06 – 1.36 0.00425 285 2551 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.48 1.22 – 1.78 5.22e-05 138 982 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.1 0.921 – 1.31 0.295 158 1167 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.06 0.987 – 1.13 0.114 1007 8632 exclusion phecode
578.1 Hematemesis Digestive 1.22 1.01 – 1.48 0.0372 117 1060 exclusion phecode
578.2 Blood in stool Digestive 1.08 0.99 – 1.18 0.0852 600 5938 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 0.992 0.901 – 1.09 0.878 476 5034 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.13 1.01 – 1.26 0.0372 349 3224 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.1 1.03 – 1.18 0.00624 975 7967 exclusion phecode
579.2 Splenomegaly Digestive 1.14 0.952 – 1.37 0.153 121 1577 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.13 1.01 – 1.27 0.0377 326 3092 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.23 1.09 – 1.38 0.000547 327 3423 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.26 1.01 – 1.58 0.0425 93 846 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.26 0.861 – 1.86 0.232 30 314 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.32 0.778 – 2.24 0.304 17 241 exclusion phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 0.943 0.549 – 1.62 0.833 13 135 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.38 1.07 – 1.79 0.0142 71 621 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.14 0.826 – 1.58 0.423 37 466 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.27 1.11 – 1.45 0.000556 249 2607 exclusion phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.28 1.07 – 1.53 0.0069 138 1500 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.24 1.04 – 1.47 0.0161 147 1449 exclusion phecode
580.4 Renal sclerosis, NOS Genitourinary 1.41 1.1 – 1.81 0.00751 71 754 exclusion phecode
585 Renal failure Genitourinary 1.24 1.16 – 1.31 1.03e-11 1352 7675 exclusion phecode
585.1 Acute renal failure Genitourinary 1.3 1.2 – 1.4 1.87e-11 803 6037 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.27 1.09 – 1.49 0.00298 182 1711 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.22 1.14 – 1.31 3.71e-08 985 6716 exclusion phecode
585.31 Renal dialysis Genitourinary 1.31 1.11 – 1.54 0.00118 176 1530 exclusion phecode
585.32 End stage renal disease Genitourinary 1.34 1.17 – 1.54 3.35e-05 238 2054 exclusion phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.21 1.09 – 1.33 0.00017 492 4489 exclusion phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.2 1.03 – 1.4 0.0195 187 1901 exclusion phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.24 1.08 – 1.43 0.00282 232 2389 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.11 1.05 – 1.18 0.000389 1476 8474 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.25 0.996 – 1.56 0.0541 86 891 exclusion phecode
586.11 Small kidney Genitourinary 1.16 0.855 – 1.58 0.335 45 515 exclusion phecode
586.12 Vesicoureteral reflux Genitourinary 1.21 0.891 – 1.65 0.22 40 401 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.05 0.923 – 1.2 0.443 257 2645 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.51 1.09 – 2.1 0.013 44 391 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.07 0.958 – 1.18 0.24 391 3829 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.36 1.18 – 1.57 2.16e-05 231 1742 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.35 1.16 – 1.56 6.54e-05 220 2000 exclusion phecode
588.1 Renal osteodystrophy Genitourinary 1.26 0.995 – 1.6 0.0555 85 582 exclusion phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.3 1.1 – 1.55 0.00258 155 1556 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.23 1.07 – 1.43 0.00503 210 2132 exclusion phecode
590 Pyelonephritis Genitourinary 1.1 0.979 – 1.24 0.11 326 3559 exclusion phecode
591 Urinary tract infection Genitourinary 1.01 0.959 – 1.06 0.783 2300 7506 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.04 0.961 – 1.13 0.327 740 5943 exclusion phecode
592.1 Cystitis Genitourinary 1.06 0.972 – 1.15 0.198 698 5747 exclusion phecode
592.11 Acute cystitis Genitourinary 1.05 0.943 – 1.16 0.39 421 4051 exclusion phecode
592.12 Chronic cystitis Genitourinary 1.25 0.925 – 1.7 0.145 49 587 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.14 0.95 – 1.38 0.156 139 1166 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.851 0.655 – 1.11 0.23 62 490 exclusion phecode
593 Hematuria Genitourinary 1.02 0.951 – 1.09 0.579 970 7381 exclusion phecode
593.1 Gross hematuria Genitourinary 1 0.887 – 1.13 0.97 285 2873 exclusion phecode
593.2 Microscopic hematuria Genitourinary 0.978 0.85 – 1.13 0.76 229 2282 exclusion phecode
594 Urinary calculus Genitourinary 1.06 0.997 – 1.13 0.0605 1206 9137 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.05 0.984 – 1.12 0.146 1117 9085 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.26 1.01 – 1.59 0.0445 80 715 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.09 0.948 – 1.24 0.232 234 3001 exclusion phecode
594.8 Renal colic Genitourinary 1.17 0.911 – 1.51 0.214 70 882 exclusion phecode
595 Hydronephrosis Genitourinary 1.16 1.04 – 1.29 0.00879 382 3817 exclusion phecode
596 Other disorders of bladder Genitourinary 1.04 0.956 – 1.13 0.366 673 5962 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.3 1.03 – 1.65 0.0281 75 680 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1.05 0.939 – 1.17 0.416 381 3817 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.976 0.861 – 1.11 0.708 278 2509 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.895 0.746 – 1.07 0.233 129 1171 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.13 0.974 – 1.3 0.109 217 2148 exclusion phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.15 0.841 – 1.57 0.381 40 454 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.43 0.915 – 2.24 0.116 25 281 exclusion phecode
598.4 Other cells and casts in urine Genitourinary 1.35 0.849 – 2.15 0.205 23 247 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.983 0.941 – 1.03 0.454 3011 7568 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.949 0.791 – 1.14 0.573 132 1245 exclusion phecode
599.2 Retention of urine Genitourinary 1.04 0.97 – 1.11 0.28 1038 6664 exclusion phecode
599.3 Dysuria Genitourinary 0.946 0.884 – 1.01 0.106 1049 6736 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.974 0.907 – 1.05 0.465 972 6365 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 0.981 0.918 – 1.05 0.574 1105 6871 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.22 1.02 – 1.46 0.0257 142 1204 exclusion phecode
599.7 Urethral discharge Genitourinary 1.03 0.626 – 1.68 0.922 18 194 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 0.967 0.905 – 1.03 0.316 1114 6590 exclusion phecode
599.9 Other abnormality of urination Genitourinary 0.959 0.881 – 1.04 0.337 621 5727 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.952 0.862 – 1.05 0.328 641 1750 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 0.961 0.815 – 1.13 0.637 157 1631 exclusion phecode
601.1 Prostatitis Genitourinary 0.937 0.734 – 1.2 0.602 76 724 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.94 0.632 – 1.4 0.762 31 199 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1.59 0.884 – 2.88 0.121 12 142 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.971 0.752 – 1.25 0.82 61 681 exclusion phecode
601.4 Balanoposthitis Genitourinary 0.803 0.479 – 1.35 0.405 13 226 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.13 0.758 – 1.69 0.548 23 286 exclusion phecode
602 Other disorders of prostate Genitourinary 0.878 0.676 – 1.14 0.332 67 483 exclusion phecode
602.3 Dysplasia of prostate Genitourinary 0.874 0.448 – 1.71 0.693 15 93 exclusion phecode
603 Other disorders of testis Genitourinary 0.984 0.794 – 1.22 0.885 86 836 exclusion phecode
603.1 Hydrocele Genitourinary 0.942 0.71 – 1.25 0.681 47 521 exclusion phecode
603.2 Spermatocele Genitourinary 0.917 0.663 – 1.27 0.599 40 283 exclusion phecode
604 Disorders of penis Genitourinary 1 0.843 – 1.19 0.968 133 1209 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.01 0.629 – 1.63 0.96 16 263 exclusion phecode
604.3 Peyronie's disease Genitourinary 0.961 0.722 – 1.28 0.784 48 330 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.924 0.836 – 1.02 0.117 496 2198 exclusion phecode
608 Other disorders of male genital organs Genitourinary 0.955 0.851 – 1.07 0.437 317 2629 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.05 0.841 – 1.31 0.666 77 860 exclusion phecode
609.1 Infertility, male Genitourinary 1.07 0.824 – 1.39 0.616 56 653 exclusion phecode
609.11 Azoospermia and oligospermia Genitourinary 1.6 0.978 – 2.63 0.0614 14 230 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.806 0.544 – 1.19 0.283 24 295 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.892 0.832 – 0.957 0.00136 1103 4593 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.876 0.794 – 0.967 0.00827 506 3675 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 0.581 0.347 – 0.972 0.0388 19 147 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.892 0.827 – 0.963 0.00348 879 4543 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.898 0.803 – 1 0.0561 390 3126 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.906 0.855 – 0.96 0.000784 1789 4939 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.882 0.828 – 0.939 9.73e-05 1489 4263 exclusion phecode
611.11 Mammographic microcalcification Genitourinary 0.847 0.754 – 0.952 0.00521 364 2535 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.894 0.834 – 0.958 0.0015 1089 4931 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.855 0.744 – 0.983 0.0282 232 2773 exclusion phecode
612.1 Galactorrhea Genitourinary 0.862 0.609 – 1.22 0.4 34 435 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.903 0.753 – 1.08 0.271 135 2033 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 0.816 0.549 – 1.21 0.314 36 230 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.941 0.88 – 1.01 0.0745 1132 5978 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 0.953 0.803 – 1.13 0.578 152 1564 exclusion phecode
613.5 Mastodynia Genitourinary 1.02 0.925 – 1.13 0.685 489 4210 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.84 0.738 – 0.956 0.00822 269 2329 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 0.853 0.748 – 0.973 0.0178 273 2469 exclusion phecode
613.9 Breast disorder NOS Genitourinary 0.954 0.859 – 1.06 0.387 424 3595 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.971 0.906 – 1.04 0.395 1089 5485 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.939 0.747 – 1.18 0.588 84 897 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.03 0.857 – 1.25 0.722 140 1356 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.23 0.836 – 1.81 0.295 31 282 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.12 0.841 – 1.5 0.436 61 500 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.934 0.722 – 1.21 0.607 72 687 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.86 0.637 – 1.16 0.326 52 476 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.961 0.894 – 1.03 0.291 944 5450 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.908 0.698 – 1.18 0.468 71 767 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.981 0.908 – 1.06 0.625 820 5315 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.21 0.85 – 1.72 0.291 37 368 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.764 0.581 – 1.01 0.0553 59 631 exclusion phecode
615 Endometriosis Genitourinary 0.996 0.898 – 1.1 0.937 433 3999 exclusion phecode
618 Genital prolapse Genitourinary 0.93 0.844 – 1.02 0.138 508 4723 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.893 0.796 – 1 0.0568 345 3445 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.905 0.76 – 1.08 0.265 145 1379 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.925 0.725 – 1.18 0.527 73 757 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.1 0.898 – 1.36 0.347 103 1118 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 0.996 0.94 – 1.06 0.901 1658 5216 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.975 0.869 – 1.09 0.664 344 3480 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 0.978 0.825 – 1.16 0.795 154 1622 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.871 0.734 – 1.03 0.112 163 1311 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.982 0.906 – 1.06 0.658 760 5121 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.06 0.938 – 1.19 0.362 326 3206 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1.09 0.897 – 1.32 0.386 118 1063 exclusion phecode
620.1 Dysplasia of cervix Genitourinary 0.918 0.698 – 1.21 0.54 57 513 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.912 0.706 – 1.18 0.48 63 1163 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.912 0.813 – 1.02 0.113 353 3805 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.844 0.739 – 0.964 0.0123 258 2965 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 0.951 0.779 – 1.16 0.621 123 1162 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 0.978 0.847 – 1.13 0.76 220 2246 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.983 0.886 – 1.09 0.74 437 3600 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.961 0.723 – 1.28 0.783 55 525 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 1.09 0.702 – 1.69 0.707 28 159 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.86 0.772 – 0.959 0.00663 388 3990 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.95 0.896 – 1.01 0.0862 1668 4852 exclusion phecode
625.1 Dyspareunia Genitourinary 0.908 0.815 – 1.01 0.0812 405 3480 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.906 0.853 – 0.963 0.00141 1676 4395 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.906 0.846 – 0.97 0.00466 1227 4097 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.95 0.838 – 1.08 0.424 304 2629 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 0.889 0.808 – 0.978 0.0153 547 3486 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.867 0.789 – 0.954 0.00344 552 3582 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.922 0.81 – 1.05 0.22 278 2647 exclusion phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.716 0.577 – 0.887 0.00229 108 1134 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.924 0.828 – 1.03 0.158 408 3005 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.789 0.638 – 0.976 0.0289 99 955 exclusion phecode
626.8 Infertility, female Genitourinary 0.799 0.697 – 0.916 0.00123 255 2068 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.887 0.829 – 0.95 0.000589 1243 3886 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 0.852 0.748 – 0.97 0.0156 277 2549 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.873 0.805 – 0.945 0.000865 834 3588 exclusion phecode
627.21 Symptomatic artificial menopause Genitourinary 1.05 0.73 – 1.5 0.809 40 402 exclusion phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.791 0.644 – 0.971 0.0248 113 855 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.865 0.764 – 0.979 0.0222 314 2315 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1.01 0.803 – 1.26 0.953 91 963 exclusion phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.878 0.72 – 1.07 0.202 118 838 exclusion phecode
628 Ovarian cyst Genitourinary 0.911 0.829 – 1 0.055 539 3925 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.02 0.891 – 1.17 0.752 244 2293 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.973 0.775 – 1.22 0.815 90 772 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.09 0.742 – 1.6 0.657 30 347 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.952 0.811 – 1.12 0.551 183 1632 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.977 0.801 – 1.19 0.817 122 1112 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.903 0.722 – 1.13 0.373 88 909 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.99 0.88 – 1.11 0.863 351 2386 exclusion phecode
636.1 Threatened premature labor Pregnancy Complications 1.04 0.858 – 1.26 0.68 131 1173 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.98 0.777 – 1.24 0.864 92 869 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.939 0.781 – 1.13 0.507 132 1359 exclusion phecode
636.8 Cervical incompetence Pregnancy Complications 0.841 0.539 – 1.31 0.447 22 245 exclusion phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.05 0.691 – 1.6 0.814 20 240 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.855 0.709 – 1.03 0.0995 129 1768 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.969 0.741 – 1.27 0.815 66 885 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.13 0.875 – 1.45 0.354 71 800 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.07 0.745 – 1.53 0.723 35 368 exclusion phecode
644 Anemia during pregnancy Pregnancy Complications 1.22 0.944 – 1.57 0.128 69 747 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.989 0.856 – 1.14 0.876 227 2138 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.01 0.777 – 1.3 0.964 75 655 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.998 0.758 – 1.31 0.989 63 712 exclusion phecode
647.3 Major puerperal infection Pregnancy Complications 1.08 0.707 – 1.66 0.709 20 204 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.947 0.843 – 1.06 0.359 367 2532 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.933 0.769 – 1.13 0.481 124 1610 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.995 0.839 – 1.18 0.951 163 1713 exclusion phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.1 0.832 – 1.45 0.508 54 637 exclusion phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 0.895 0.688 – 1.16 0.41 65 637 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.893 0.81 – 0.985 0.0241 514 3055 exclusion phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 0.88 0.75 – 1.03 0.117 188 1757 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.01 0.877 – 1.15 0.931 253 2170 exclusion phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 1.08 0.497 – 2.36 0.842 5 144 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.978 0.855 – 1.12 0.742 266 2143 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.08 0.824 – 1.42 0.575 64 707 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.891 0.649 – 1.22 0.475 44 543 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.808 0.623 – 1.05 0.105 63 580 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.15 1.08 – 1.22 4.43e-06 1331 9223 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.06 0.931 – 1.21 0.376 259 2612 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.24 1.07 – 1.42 0.00316 224 2219 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.27 1.15 – 1.42 8.11e-06 397 4472 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.25 1.13 – 1.39 2.95e-05 406 4641 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.3 1.16 – 1.46 1.05e-05 330 3685 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.21 1.06 – 1.37 0.00333 285 3560 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.11 1.01 – 1.22 0.0362 485 4893 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 0.895 0.734 – 1.09 0.269 114 1391 exclusion phecode
686.2 Impetigo Dermatologic 1.07 0.868 – 1.33 0.51 102 1017 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.25 0.869 – 1.8 0.23 28 403 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 0.818 0.579 – 1.16 0.254 34 380 exclusion phecode
686.5 Pyoderma Dermatologic 1.52 0.809 – 2.86 0.192 8 144 exclusion phecode
687 Symptoms affecting skin Dermatologic 0.984 0.89 – 1.09 0.757 449 3752 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.01 0.953 – 1.06 0.805 1623 8190 exclusion phecode
687.3 Changes in skin texture Dermatologic 1.04 0.83 – 1.32 0.71 85 837 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.05 0.992 – 1.12 0.0889 1359 8010 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.96 0.915 – 1.01 0.104 2241 8716 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.908 0.851 – 0.968 0.00312 1200 6764 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.907 0.851 – 0.968 0.0031 1200 6752 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.852 0.702 – 1.03 0.104 123 1322 exclusion phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 1.18 0.764 – 1.81 0.46 21 163 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.912 0.829 – 1 0.057 500 4084 exclusion phecode
694.1 Vitiligo Dermatologic 1.13 0.797 – 1.59 0.503 37 300 exclusion phecode
694.2 Other dyschromia Dermatologic 0.901 0.814 – 0.996 0.0424 447 3711 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.19 0.732 – 1.93 0.486 24 163 exclusion phecode
695 Erythematous conditions Dermatologic 0.981 0.912 – 1.06 0.617 844 6904 exclusion phecode
695.1 Toxic erythema Dermatologic 0.982 0.593 – 1.63 0.945 15 173 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.1 0.649 – 1.86 0.725 20 172 exclusion phecode
695.3 Rosacea Dermatologic 0.817 0.731 – 0.912 0.000343 366 3953 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.14 0.976 – 1.33 0.0986 185 1711 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.12 0.85 – 1.48 0.413 67 616 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.16 0.99 – 1.36 0.066 177 1613 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 0.927 0.759 – 1.13 0.456 113 1324 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1.03 0.841 – 1.25 0.802 105 1866 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.822 0.484 – 1.4 0.467 15 165 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.14 0.952 – 1.36 0.155 132 1504 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.97 0.855 – 1.1 0.632 275 3123 exclusion phecode
696.3 Pityriasis Dermatologic 0.708 0.484 – 1.04 0.0764 36 277 exclusion phecode
696.4 Psoriasis Dermatologic 1 0.874 – 1.15 0.993 238 2876 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.993 0.863 – 1.14 0.919 222 2603 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.892 0.655 – 1.21 0.466 41 615 exclusion phecode
697 Sarcoidosis Dermatologic 1.04 0.78 – 1.39 0.778 47 653 exclusion phecode
698 Pruritus and related conditions Dermatologic 0.984 0.899 – 1.08 0.727 557 5421 exclusion phecode
700 Corns and callosities Dermatologic 1.02 0.885 – 1.17 0.802 229 2355 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.967 0.916 – 1.02 0.218 1735 9024 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 1.07 0.892 – 1.28 0.469 141 1181 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.996 0.914 – 1.09 0.927 623 5144 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.948 0.789 – 1.14 0.57 133 1404 exclusion phecode
701.4 Keloid scar Dermatologic 0.916 0.774 – 1.09 0.311 158 1531 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1.03 0.824 – 1.3 0.771 91 904 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.903 0.852 – 0.958 0.000705 1588 6196 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.87 0.809 – 0.935 0.000171 950 5238 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.907 0.851 – 0.967 0.00268 1277 6486 exclusion phecode
702.4 Degenerative skin disorders Dermatologic 1.17 0.75 – 1.84 0.482 25 197 exclusion phecode
703 Diseases of nail, NOS Dermatologic 0.911 0.811 – 1.02 0.115 333 3307 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.913 0.776 – 1.07 0.267 167 1978 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.993 0.92 – 1.07 0.854 765 7325 exclusion phecode
704.1 Alopecia Dermatologic 0.955 0.859 – 1.06 0.391 409 3630 exclusion phecode
704.11 Alopecia Areata Dermatologic 1.23 0.779 – 1.93 0.379 21 179 exclusion phecode
704.12 Telogen effluvium Dermatologic 0.949 0.568 – 1.59 0.843 22 160 exclusion phecode
704.2 Hirsutism Dermatologic 1.17 0.873 – 1.58 0.288 45 882 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.03 0.925 – 1.15 0.575 375 3901 exclusion phecode
705 Disorders of sweat glands Dermatologic 1.09 0.894 – 1.32 0.399 115 1541 exclusion phecode
705.1 Dyshidrosis Dermatologic 0.889 0.611 – 1.3 0.541 33 340 exclusion phecode
705.3 Hidradenitis Dermatologic 1.19 0.841 – 1.7 0.32 33 639 exclusion phecode
705.8 Hyperhidrosis Dermatologic 0.926 0.813 – 1.06 0.25 263 2649 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 0.91 0.86 – 0.962 0.000983 1531 9248 exclusion phecode
706.1 Acne Dermatologic 0.883 0.82 – 0.952 0.00117 832 5978 exclusion phecode
706.2 Sebaceous cyst Dermatologic 0.937 0.862 – 1.02 0.13 644 6019 exclusion phecode
706.3 Seborrhea Dermatologic 0.88 0.505 – 1.53 0.652 16 137 exclusion phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.982 0.874 – 1.1 0.755 322 3244 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.25 1.15 – 1.36 4.39e-07 597 5738 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.41 1.21 – 1.65 8.27e-06 206 1652 exclusion phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.37 1.17 – 1.6 7.03e-05 180 1928 exclusion phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1.27 1.14 – 1.42 2.01e-05 356 3547 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 1.06 0.947 – 1.18 0.324 383 3529 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.01 0.845 – 1.21 0.911 132 1192 exclusion phecode
709.3 Systemic sclerosis Dermatologic 1.02 0.797 – 1.32 0.851 72 515 exclusion phecode
709.5 Dermatomyositis Dermatologic 1.24 0.793 – 1.94 0.347 18 210 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.74 1.11 – 2.73 0.0151 27 213 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.01 0.879 – 1.16 0.883 239 2277 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.26 1.11 – 1.42 0.000384 282 2616 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.26 1.11 – 1.43 0.000346 275 2462 exclusion phecode
710.11 Acute osteomyelitis Musculoskeletal 1.34 1.12 – 1.62 0.00163 130 1196 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.3 1.08 – 1.58 0.00578 126 1049 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.27 1.11 – 1.44 0.000385 258 2362 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 0.931 0.738 – 1.17 0.543 77 883 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.28 0.938 – 1.75 0.12 46 610 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.13 0.782 – 1.63 0.514 31 400 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.09 0.84 – 1.41 0.523 62 642 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.44 0.909 – 2.29 0.12 20 304 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.12 1.02 – 1.24 0.0234 468 4438 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.16 1.04 – 1.3 0.00614 386 3663 exclusion phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.31 0.93 – 1.84 0.123 33 237 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.07 0.933 – 1.22 0.345 244 2802 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.04 0.797 – 1.36 0.767 57 676 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.18 0.882 – 1.57 0.268 50 545 exclusion phecode
716 Other arthropathies Musculoskeletal 1.06 1.01 – 1.11 0.0211 2506 7939 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.868 0.605 – 1.24 0.44 33 432 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.888 0.575 – 1.37 0.594 20 272 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.06 1.01 – 1.12 0.0149 2492 7936 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.18 0.879 – 1.57 0.276 52 562 exclusion phecode
720 Spinal stenosis Musculoskeletal 1.07 0.984 – 1.16 0.114 649 6151 exclusion phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1.12 1.01 – 1.24 0.0375 428 4881 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1.07 1 – 1.15 0.0378 1075 7226 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.08 1 – 1.15 0.0373 1008 7068 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.07 0.899 – 1.28 0.442 152 1737 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 1.02 0.741 – 1.4 0.909 40 562 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.06 0.995 – 1.13 0.0702 1199 8037 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.06 0.98 – 1.16 0.137 659 7186 exclusion phecode
722.3 Schmorl's nodes Musculoskeletal 1.08 0.744 – 1.58 0.675 32 264 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.08 1 – 1.17 0.0409 752 6798 exclusion phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.1 0.874 – 1.38 0.421 92 1084 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.13 0.88 – 1.46 0.332 73 827 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.962 0.862 – 1.07 0.496 370 4256 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.01 0.883 – 1.17 0.835 230 2233 exclusion phecode
723.1 Torticollis Musculoskeletal 0.973 0.745 – 1.27 0.84 62 589 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.04 0.972 – 1.12 0.234 890 7601 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1.05 0.951 – 1.15 0.357 520 5376 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.88 0.708 – 1.09 0.25 98 1021 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.14 0.971 – 1.33 0.112 175 2182 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.07 0.948 – 1.22 0.266 288 3198 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.935 0.889 – 0.983 0.00881 2111 7342 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.924 0.873 – 0.977 0.00564 1605 7313 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.917 0.783 – 1.07 0.285 173 2098 exclusion phecode
726.3 Bursitis Musculoskeletal 0.877 0.786 – 0.979 0.0197 359 3818 exclusion phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.884 0.771 – 1.01 0.0779 228 2653 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.975 0.922 – 1.03 0.389 1618 7309 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.951 0.876 – 1.03 0.236 681 6062 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.913 0.725 – 1.15 0.438 80 907 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.98 0.875 – 1.1 0.722 347 3217 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.953 0.756 – 1.2 0.685 89 1092 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.963 0.87 – 1.07 0.469 420 4585 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.12 0.947 – 1.32 0.19 167 1482 exclusion phecode
727.8 Plica syndrome Musculoskeletal 0.969 0.712 – 1.32 0.842 50 385 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.977 0.912 – 1.05 0.512 988 7020 exclusion phecode
728.1 Muscular calcification and ossification Musculoskeletal 1.11 0.726 – 1.7 0.627 22 186 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.03 0.828 – 1.29 0.776 77 712 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.829 0.753 – 0.912 0.000117 473 5331 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.674 0.545 – 0.833 0.000259 108 781 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.1 1.01 – 1.19 0.0248 669 6222 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.76 1.08 – 2.86 0.0234 19 168 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.924 0.535 – 1.6 0.777 9 304 exclusion phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 1.01 0.6 – 1.69 0.981 21 155 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.52 1.07 – 2.18 0.0206 36 353 exclusion phecode
732 Osteochondropathies Musculoskeletal 1.13 0.904 – 1.42 0.279 91 1000 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.23 0.864 – 1.76 0.248 40 530 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.28 0.823 – 2 0.271 24 265 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.956 0.896 – 1.02 0.172 1259 6039 exclusion phecode
733.2 Cyst of bone Musculoskeletal 0.963 0.712 – 1.3 0.805 53 452 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.08 0.911 – 1.27 0.389 160 1061 exclusion phecode
733.6 Costochondritis Musculoskeletal 0.869 0.692 – 1.09 0.229 79 878 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.2 1.03 – 1.39 0.0171 207 1900 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.17 0.798 – 1.7 0.429 33 261 exclusion phecode
735 Acquired foot deformities Musculoskeletal 0.98 0.907 – 1.06 0.611 762 6663 exclusion phecode
735.1 Flat foot Musculoskeletal 0.893 0.735 – 1.08 0.254 109 1399 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 1.01 0.89 – 1.15 0.864 279 2535 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.16 0.974 – 1.37 0.0974 160 1562 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.997 0.808 – 1.23 0.979 103 848 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.916 0.817 – 1.03 0.133 348 3312 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 0.969 0.889 – 1.06 0.473 614 6048 exclusion phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.847 0.577 – 1.24 0.395 32 220 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.22 0.924 – 1.61 0.161 66 463 exclusion phecode
736.3 Acquired deformities of hip Musculoskeletal 0.751 0.436 – 1.29 0.301 16 188 exclusion phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 1.13 0.839 – 1.51 0.428 48 682 exclusion phecode
736.5 Acquired deformities of knee Musculoskeletal 0.962 0.685 – 1.35 0.821 32 499 exclusion phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.828 0.647 – 1.06 0.136 78 779 exclusion phecode
737 Curvature of spine Musculoskeletal 1.02 0.923 – 1.12 0.713 462 3890 exclusion phecode
737.1 Kyphosis (acquired) Musculoskeletal 1.07 0.879 – 1.29 0.51 110 1080 exclusion phecode
737.2 Lordosis (acquired) Musculoskeletal 1.96 1.06 – 3.65 0.0327 12 152 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.02 0.916 – 1.14 0.724 386 3060 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.09 1 – 1.19 0.0487 631 5535 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.1 0.95 – 1.28 0.197 198 2157 exclusion phecode
739 Contracture of joint Musculoskeletal 0.986 0.829 – 1.17 0.873 160 1370 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.04 0.991 – 1.09 0.112 2937 7929 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.955 0.893 – 1.02 0.178 1157 6673 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.953 0.888 – 1.02 0.184 1023 6187 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.07 0.888 – 1.29 0.477 122 1668 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.01 0.89 – 1.14 0.917 306 2887 exclusion phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 1.25 0.977 – 1.61 0.0757 71 857 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.04 0.991 – 1.09 0.11 2783 7867 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.01 0.955 – 1.06 0.841 1879 8544 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.922 0.702 – 1.21 0.555 54 599 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.02 0.907 – 1.15 0.727 323 2891 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 1.06 0.965 – 1.16 0.227 496 4936 exclusion phecode
741.4 Joint effusions Musculoskeletal 0.99 0.904 – 1.08 0.823 540 5845 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.1 0.696 – 1.75 0.673 18 199 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.94 0.497 – 1.78 0.849 11 169 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.995 0.931 – 1.06 0.886 1043 8142 exclusion phecode
742.1 Loose body in joint Musculoskeletal 1.02 0.71 – 1.46 0.922 28 422 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.964 0.775 – 1.2 0.745 85 933 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.02 0.789 – 1.31 0.887 62 634 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.998 0.932 – 1.07 0.953 985 8034 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.03 0.982 – 1.08 0.218 2537 8248 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.07 1 – 1.15 0.0468 1230 3995 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.07 0.999 – 1.15 0.0533 1217 3952 exclusion phecode
743.12 Senile osteoporosis Musculoskeletal 0.955 0.835 – 1.09 0.509 292 1134 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1.11 0.901 – 1.38 0.317 109 601 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 0.985 0.873 – 1.11 0.805 326 2028 exclusion phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 1.01 0.835 – 1.23 0.904 131 862 exclusion phecode
743.22 Pathologic fracture of femur Musculoskeletal 1.6 1.13 – 2.26 0.0086 43 267 exclusion phecode
743.4 Stress fracture Musculoskeletal 0.845 0.69 – 1.03 0.101 120 924 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.02 0.968 – 1.08 0.418 1853 7744 exclusion phecode
745 Pain in joint Musculoskeletal 0.966 0.928 – 1 0.0808 4517 6498 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.02 0.931 – 1.12 0.666 525 4965 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.04 0.938 – 1.16 0.438 389 3920 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.959 0.816 – 1.13 0.614 170 1512 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.06 0.885 – 1.28 0.514 128 1550 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.11 0.895 – 1.38 0.344 88 884 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.996 0.831 – 1.19 0.965 140 1163 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.47 0.963 – 2.23 0.0742 29 272 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.887 0.763 – 1.03 0.118 206 1544 exclusion phecode
749.1 Cleft palate Congenital Anomalies 0.853 0.633 – 1.15 0.299 43 310 exclusion phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.917 0.678 – 1.24 0.572 46 303 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 1.12 0.978 – 1.28 0.102 261 2050 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.972 0.777 – 1.22 0.807 88 858 exclusion phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.85 0.578 – 1.25 0.41 29 248 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.03 0.69 – 1.55 0.872 24 258 exclusion phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 0.819 0.583 – 1.15 0.249 39 269 exclusion phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 1.68 0.798 – 3.52 0.172 11 122 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.13 0.959 – 1.33 0.145 176 1251 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.15 0.942 – 1.4 0.169 110 720 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.23 0.944 – 1.61 0.124 69 509 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.01 0.921 – 1.11 0.815 518 4659 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.04 0.879 – 1.23 0.644 161 1548 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.09 0.888 – 1.33 0.424 116 1100 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.818 0.578 – 1.16 0.257 38 353 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.947 0.844 – 1.06 0.354 332 3026 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.973 0.846 – 1.12 0.702 227 2060 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.93 0.736 – 1.18 0.546 74 675 exclusion phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.14 0.868 – 1.49 0.348 62 532 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.09 0.943 – 1.25 0.25 227 2647 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.13 0.965 – 1.33 0.129 177 2072 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.872 0.634 – 1.2 0.402 42 500 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.9 0.675 – 1.2 0.474 58 599 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.09 0.794 – 1.5 0.584 52 476 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.6 0.347 – 1.04 0.0672 14 150 exclusion phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 1.18 0.652 – 2.12 0.588 14 144 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.07 0.935 – 1.23 0.326 247 2582 exclusion phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 0.791 0.536 – 1.17 0.237 27 305 exclusion phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 1.13 0.929 – 1.38 0.217 109 1222 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.11 0.94 – 1.3 0.224 175 1999 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.955 0.758 – 1.2 0.694 78 912 exclusion phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 1.21 0.73 – 2.01 0.46 18 180 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.21 0.953 – 1.52 0.12 84 961 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.24 0.91 – 1.68 0.174 50 565 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.04 0.931 – 1.17 0.468 354 3352 exclusion phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.966 0.601 – 1.55 0.885 21 172 exclusion phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 1.18 0.834 – 1.66 0.352 49 237 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.82 0.634 – 1.06 0.131 62 840 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.07 0.931 – 1.23 0.348 229 2290 exclusion phecode
757 Congenital anomalies of the integument Congenital Anomalies 1.04 0.843 – 1.29 0.7 103 926 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.01 0.753 – 1.35 0.958 58 491 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.953 0.678 – 1.34 0.784 38 363 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.944 0.801 – 1.11 0.49 160 1493 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.607 0.357 – 1.03 0.0638 14 188 exclusion phecode
760 Back pain Symptoms 1.07 1.02 – 1.11 0.00215 3440 7569 exclusion phecode
761 Cervicalgia Symptoms 1.01 0.959 – 1.07 0.628 1576 9228 exclusion phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 1 0.924 – 1.09 0.954 662 7263 exclusion phecode
764 Sciatica Symptoms 1.06 0.974 – 1.16 0.174 611 7266 exclusion phecode
765 Cervical radiculitis Symptoms 1.08 0.964 – 1.2 0.194 371 3862 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.03 0.965 – 1.1 0.358 1017 8661 exclusion phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.15 0.772 – 1.7 0.498 28 264 exclusion phecode
769 Nonallopathic lesions NEC Symptoms 1.04 0.916 – 1.18 0.552 292 2634 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.07 1 – 1.14 0.0374 1254 8242 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.07 1 – 1.15 0.0354 1015 8355 exclusion phecode
771.1 Swelling of limb Symptoms 1.1 1.03 – 1.18 0.00378 1061 8316 exclusion phecode
771.2 Cramp of limb Symptoms 0.986 0.86 – 1.13 0.84 233 2375 exclusion phecode
772 Symptoms of the muscles Symptoms 0.958 0.873 – 1.05 0.372 507 4726 exclusion phecode
772.1 Muscular wasting and disuse atrophy Symptoms 0.904 0.74 – 1.11 0.326 123 1091 exclusion phecode
772.2 Spasm of muscle Symptoms 1.06 0.964 – 1.16 0.244 542 5508 exclusion phecode
772.3 Muscle weakness Symptoms 1.05 0.961 – 1.14 0.298 640 6137 exclusion phecode
772.4 Rhabdomyolysis Symptoms 1.53 1.05 – 2.23 0.0268 38 338 exclusion phecode
772.6 Facial weakness Symptoms 1.01 0.813 – 1.25 0.954 96 1027 exclusion phecode
780 Hypothermia/Chills Symptoms 1.19 0.958 – 1.47 0.118 104 987 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.98 0.897 – 1.07 0.663 574 5709 exclusion phecode
781.1 Loss of height Symptoms 1.33 0.932 – 1.91 0.116 35 214 exclusion phecode
781.2 Abnormal posture Symptoms 0.812 0.474 – 1.39 0.448 14 123 exclusion phecode
782.3 Edema Symptoms 1.19 1.11 – 1.27 8.45e-07 976 8470 exclusion phecode
782.6 Pallor and flushing Symptoms 0.9 0.785 – 1.03 0.135 245 2410 exclusion phecode
783 Fever of unknown origin Symptoms 1.13 1.06 – 1.2 5.53e-05 1350 9562 exclusion phecode
783.1 Postprocedural fever Symptoms 0.973 0.738 – 1.28 0.845 58 642 exclusion phecode
785 Abdominal pain Symptoms 1.06 1.02 – 1.11 0.0027 3950 7061 exclusion phecode
788 Syncope and collapse Symptoms 1.03 0.962 – 1.11 0.372 887 8223 exclusion phecode
789 Nausea and vomiting Symptoms 1.06 1.01 – 1.11 0.0124 2685 8302 exclusion phecode
789.1 Persistent vomiting Symptoms 1.24 1.07 – 1.44 0.00395 203 1910 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.15 1.05 – 1.26 0.00377 499 4987 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.13 0.834 – 1.52 0.435 42 564 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.13 1.06 – 1.19 6.97e-05 1441 9098 exclusion phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.25 0.932 – 1.68 0.136 46 771 exclusion phecode
790.9 Abnormal arterial blood gases Symptoms 1.22 0.827 – 1.8 0.316 27 339 exclusion phecode
791 Gangrene Symptoms 1.25 0.988 – 1.58 0.0626 77 589 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 0.998 0.925 – 1.08 0.969 885 4183 exclusion phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 1.03 0.915 – 1.15 0.668 370 2793 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.959 0.773 – 1.19 0.705 96 1118 exclusion phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 1.07 0.985 – 1.17 0.109 639 5303 exclusion phecode
795.8 Abnormal tumor markers Symptoms 0.922 0.816 – 1.04 0.196 295 2567 exclusion phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 0.993 0.496 – 1.99 0.984 11 129 exclusion phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 1.05 0.789 – 1.4 0.737 59 490 exclusion phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.826 0.727 – 0.939 0.00357 314 1514 exclusion phecode
797 Shock Symptoms 1.18 0.969 – 1.42 0.1 129 1151 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.28 0.951 – 1.72 0.104 54 436 exclusion phecode
798 Malaise and fatigue Symptoms 1.05 1.01 – 1.1 0.0227 2655 8349 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1.09 0.976 – 1.21 0.129 383 4177 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.02 0.938 – 1.12 0.605 595 5364 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.11 0.932 – 1.32 0.246 151 1086 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.06 0.908 – 1.23 0.466 192 1460 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.03 0.893 – 1.19 0.69 221 2131 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.911 0.744 – 1.12 0.368 105 871 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.03 0.937 – 1.12 0.572 536 5414 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 0.981 0.859 – 1.12 0.781 249 2719 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 0.988 0.814 – 1.2 0.899 123 885 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.968 0.889 – 1.05 0.455 608 4860 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 0.934 0.797 – 1.09 0.394 177 1770 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.966 0.864 – 1.08 0.544 360 2789 exclusion phecode
803.21 Colles' fracture Injuries & Poisonings 0.97 0.779 – 1.21 0.784 93 688 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.974 0.835 – 1.14 0.743 176 1228 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 1.01 0.922 – 1.12 0.765 491 3985 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.05 0.933 – 1.17 0.432 347 2856 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.08 0.925 – 1.27 0.316 177 1371 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.998 0.926 – 1.07 0.954 829 6736 exclusion phecode
816 Cerebral laceration and contusion Injuries & Poisonings 1.01 0.581 – 1.75 0.973 16 101 exclusion phecode
817 Concussion Injuries & Poisonings 1.05 0.924 – 1.2 0.442 258 2679 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.17 0.929 – 1.46 0.185 85 688 exclusion phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 1.43 0.883 – 2.33 0.145 24 189 exclusion phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.21 0.781 – 1.88 0.391 24 203 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.05 0.966 – 1.15 0.242 607 5516 exclusion phecode
830 Dislocation Injuries & Poisonings 0.914 0.851 – 0.982 0.0144 868 8371 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.849 0.771 – 0.936 0.00098 465 5322 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.842 0.664 – 1.07 0.157 80 1028 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.911 0.864 – 0.96 0.000511 1782 9030 exclusion phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 1.05 0.831 – 1.32 0.703 82 1115 exclusion phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.9 0.789 – 1.03 0.114 253 3256 exclusion phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.857 0.792 – 0.927 0.000119 746 6296 exclusion phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.927 0.825 – 1.04 0.198 339 3848 exclusion phecode
842 Other sprains and strains Injuries & Poisonings 0.928 0.828 – 1.04 0.198 334 3490 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.19 1.07 – 1.31 0.000714 461 4470 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.23 1.13 – 1.33 7.89e-07 669 5863 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.39 1.12 – 1.71 0.00275 107 959 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.25 1.12 – 1.38 2.92e-05 412 4147 exclusion phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 0.937 0.71 – 1.24 0.644 54 619 exclusion phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.08 0.819 – 1.42 0.591 59 578 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.18 1.04 – 1.35 0.0122 269 3092 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.08 0.986 – 1.19 0.0973 517 5130 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.18 1.08 – 1.29 0.000287 567 4779 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.12 0.789 – 1.6 0.517 40 366 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.11 1.03 – 1.18 0.00358 997 8403 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.26 0.951 – 1.67 0.106 55 444 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 0.879 0.634 – 1.22 0.441 41 324 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.01 0.905 – 1.12 0.888 392 3010 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.08 0.821 – 1.42 0.584 60 476 exclusion phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 0.992 0.795 – 1.24 0.943 93 604 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 1.1 0.844 – 1.44 0.476 64 395 exclusion phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.22 0.88 – 1.68 0.236 38 391 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.08 1 – 1.16 0.0443 808 7420 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.963 0.798 – 1.16 0.696 128 1282 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.957 0.833 – 1.1 0.537 233 2284 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.48 1.18 – 1.87 0.000869 85 951 exclusion phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.32 0.977 – 1.79 0.0707 44 583 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.4 1.14 – 1.71 0.0012 109 1075 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.32 0.932 – 1.88 0.117 34 304 exclusion phecode
875 Non-healing surgical wound Injuries & Poisonings 1.22 1.01 – 1.46 0.0346 127 1275 exclusion phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.21 1.03 – 1.44 0.0245 148 1736 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.09 0.95 – 1.24 0.226 237 2291 exclusion phecode
910 Superficial injury, infected Injuries & Poisonings 1.1 0.715 – 1.7 0.656 22 268 exclusion phecode
911 Blister Injuries & Poisonings 1.01 0.764 – 1.33 0.962 50 571 exclusion phecode
912 Insect bite Injuries & Poisonings 0.995 0.818 – 1.21 0.957 112 1187 exclusion phecode
913 Toxic effect of venom Injuries & Poisonings 0.781 0.627 – 0.972 0.0265 85 744 exclusion phecode
916 Contusion Injuries & Poisonings 1.02 0.951 – 1.09 0.616 987 8993 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 1.14 0.977 – 1.34 0.096 184 2047 exclusion phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.98 0.82 – 1.17 0.822 149 1629 exclusion phecode
938 Dermatitis due to solar radiation Dermatologic 0.916 0.861 – 0.974 0.00536 1328 6321 exclusion phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.919 0.687 – 1.23 0.571 48 508 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.911 0.856 – 0.971 0.004 1269 6176 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.961 0.907 – 1.02 0.177 1492 7699 exclusion phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 1.48 0.935 – 2.34 0.0941 28 224 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.865 0.622 – 1.2 0.388 37 380 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.21 0.945 – 1.56 0.13 76 617 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.892 0.743 – 1.07 0.223 125 1147 exclusion phecode
947 Urticaria Dermatologic 0.922 0.815 – 1.04 0.196 287 2944 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.03 0.972 – 1.09 0.34 1617 7675 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.19 0.967 – 1.45 0.101 107 1049 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.7 0.476 – 1.03 0.0708 34 324 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.09 0.968 – 1.24 0.152 305 2721 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1 0.708 – 1.42 0.994 38 329 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.861 0.59 – 1.26 0.437 34 249 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.18 1.08 – 1.29 0.000351 552 5167 exclusion phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 1.05 0.839 – 1.32 0.653 88 767 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.19 1.06 – 1.33 0.00319 342 3712 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.28 1.06 – 1.53 0.00851 138 1185 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.21 1.06 – 1.39 0.0063 233 2385 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.16 0.992 – 1.37 0.0622 172 1659 exclusion phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.15 0.918 – 1.44 0.222 84 794 exclusion phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 1.85 0.983 – 3.47 0.0566 11 118 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.18 0.957 – 1.46 0.121 99 974 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.17 1.08 – 1.27 0.000175 662 5444 exclusion phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.19 1.09 – 1.29 8.38e-05 644 5337 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.29 1.07 – 1.56 0.00653 129 1472 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.28 1.06 – 1.55 0.0115 120 1391 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.14 0.98 – 1.33 0.0883 199 2115 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.33 1.18 – 1.49 3.78e-06 303 3397 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.01 0.68 – 1.5 0.956 27 247 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.14 0.763 – 1.7 0.527 28 229 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.07 0.948 – 1.21 0.273 305 2905 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.49 1.16 – 1.92 0.00158 74 697 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.29 0.751 – 2.23 0.354 18 124 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.32 0.991 – 1.75 0.0575 51 576 exclusion phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 1.12 0.66 – 1.89 0.682 13 157 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.78 1.06 – 2.97 0.0289 16 198 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.14 0.714 – 1.83 0.576 21 234 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1 0.564 – 1.79 0.991 14 199 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.806 0.456 – 1.42 0.457 15 160 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.13 1.02 – 1.26 0.0221 383 3849 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.17 1.08 – 1.26 6.45e-05 797 7171 exclusion phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 1.07 0.944 – 1.21 0.296 288 2809 exclusion phecode
985 Toxic effect of other metals Injuries & Poisonings 1.15 0.619 – 2.15 0.654 17 92 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.2 0.844 – 1.71 0.309 34 302 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.1 1.02 – 1.18 0.00837 954 6503 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.29 1.17 – 1.43 5.53e-07 461 4485 exclusion phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.19 0.915 – 1.54 0.196 74 650 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.29 1.16 – 1.43 1.38e-06 429 4266 exclusion phecode
994.21 Septic shock Injuries & Poisonings 1.29 1.07 – 1.55 0.00693 138 1270 exclusion phecode
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