Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Body mass index Michigan Genomics Initiative Freeze 3 (MGI) PheWAS analysis

Body mass index — Michigan Genomics Initiative Freeze 3 (MGI) PRS PheWAS

PRS model
PRS ID exprsweb-bmi-23104-raw-lassosum-mgi-freeze3-20211120Legacy LASSOSUMlassosumUK Biobank GWAS

Evaluation cohort: Michigan Genomics Initiative Freeze 3 (MGI).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: normal-range subset (18.5-24.9).

For this ExPRS, the exclusion sensitivity scan keeps only the study's normal-range subset for Body mass index (18.5-24.9) before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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710 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.04 1 – 1.08 0.04 3004 29292 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.12 1.05 – 1.18 0.00025 1322 13162 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.11 1.04 – 1.19 0.00117 1046 10455 all phecode
008.6 Viral Enteritis Infectious Diseases 1.08 1.01 – 1.17 0.0345 770 7676 all phecode
010 Tuberculosis Infectious Diseases 1.1 0.964 – 1.26 0.152 244 2425 all phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.961 0.762 – 1.21 0.737 86 855 all phecode
038 Septicemia Infectious Diseases 1.14 1.09 – 1.18 2.87e-09 2582 24779 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.15 1.05 – 1.26 0.00228 568 5629 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.2 1.04 – 1.38 0.00975 235 2350 all phecode
038.3 Bacteremia Infectious Diseases 1.13 1.06 – 1.2 0.000101 1210 12079 all phecode
041 Bacterial infection NOS Infectious Diseases 1.09 1.06 – 1.13 4.76e-10 5750 38799 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.2 1.14 – 1.27 1.66e-12 1707 16977 all phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.23 1.15 – 1.32 4.26e-09 920 9192 all phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.17 1.09 – 1.27 2.79e-05 783 7812 all phecode
041.2 Streptococcus infection Infectious Diseases 1.11 1.05 – 1.17 0.000175 1632 16287 all phecode
041.21 Rheumatic fever / chorea Infectious Diseases 0.993 0.87 – 1.13 0.913 257 2554 all phecode
041.4 E. coli Infectious Diseases 1.11 1.04 – 1.18 0.00161 1175 11680 all phecode
041.8 H. pylori Infectious Diseases 1.03 0.901 – 1.18 0.672 257 2521 all phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.23 1.11 – 1.37 0.000158 387 3864 all phecode
053 Herpes zoster Infectious Diseases 0.92 0.872 – 0.971 0.00242 1560 15184 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.871 0.755 – 1 0.0575 220 2169 all phecode
054 Herpes simplex Infectious Diseases 0.903 0.856 – 0.952 0.000157 1593 15600 all phecode
070 Viral hepatitis Infectious Diseases 1.04 0.962 – 1.11 0.356 829 8280 all phecode
070.1 Viral hepatitis A Infectious Diseases 0.988 0.792 – 1.23 0.918 87 860 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.04 0.898 – 1.2 0.617 215 2138 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.05 0.953 – 1.15 0.346 528 5280 all phecode
070.4 Chronic hepatitis Infectious Diseases 0.983 0.844 – 1.14 0.823 197 1964 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.01 0.95 – 1.08 0.717 1145 11381 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.12 0.95 – 1.33 0.174 145 1450 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.1 0.917 – 1.33 0.299 117 1163 all phecode
078 Viral warts & HPV Infectious Diseases 0.91 0.877 – 0.944 3.56e-07 3434 29624 all phecode
079 Viral infection Infectious Diseases 0.94 0.915 – 0.966 7.54e-06 6664 35342 all phecode
079.1 Varicella infection Infectious Diseases 0.882 0.852 – 0.913 1.81e-12 3793 31251 all phecode
079.2 Infectious mononucleosis Infectious Diseases 0.926 0.818 – 1.05 0.224 283 2723 all phecode
079.9 Viremia, NOS Infectious Diseases 1.05 0.979 – 1.13 0.163 838 8253 all phecode
080 Postoperative infection Infectious Diseases 1.18 1.13 – 1.23 2.2e-15 2619 26065 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.13 1.07 – 1.19 6.56e-06 1589 15884 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.997 0.932 – 1.07 0.924 965 9630 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.02 0.982 – 1.06 0.335 3544 30054 all phecode
110.1 Dermatophytosis Infectious Diseases 1.03 0.989 – 1.07 0.17 3241 27244 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.04 0.992 – 1.09 0.105 2044 16765 all phecode
110.12 Althete's foot Infectious Diseases 1.06 0.991 – 1.14 0.0862 899 8043 all phecode
110.13 Dermatophytosis of the body Infectious Diseases 1.03 0.958 – 1.11 0.401 790 7827 all phecode
110.2 Dermatomycoses Infectious Diseases 0.969 0.873 – 1.08 0.554 398 3971 all phecode
112 Candidiasis Infectious Diseases 1.11 1.07 – 1.15 2.51e-08 3685 30495 all phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.31 1.2 – 1.42 1.27e-10 682 6732 all phecode
117 Mycoses Infectious Diseases 1.01 0.932 – 1.1 0.747 608 6069 all phecode
117.1 Histoplasmosis Infectious Diseases 1.08 0.857 – 1.35 0.53 81 801 all phecode
117.4 Aspergillosis Infectious Diseases 1.04 0.877 – 1.24 0.635 140 1387 all phecode
130 Spirochetal infection Infectious Diseases 0.887 0.758 – 1.04 0.135 168 1677 all phecode
130.1 Lyme disease Infectious Diseases 0.835 0.689 – 1.01 0.0664 116 1160 all phecode
131 Protozoan infection Infectious Diseases 1.34 1.05 – 1.72 0.019 61 610 all phecode
132 Infestation (lice, mites) Infectious Diseases 1.17 1.01 – 1.36 0.0391 195 1948 all phecode
134 Helminthiases Infectious Diseases 0.984 0.783 – 1.24 0.887 83 812 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.07 0.808 – 1.43 0.627 53 513 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.04 1 – 1.08 0.0392 3279 32486 all phecode
145 Cancer of mouth Neoplasms 1.05 0.998 – 1.11 0.0579 1481 14725 all phecode
145.1 Cancer of lip Neoplasms 1.19 0.942 – 1.51 0.144 76 750 all phecode
145.2 Cancer of tongue Neoplasms 1.01 0.934 – 1.1 0.734 645 6430 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.04 0.929 – 1.16 0.508 361 3597 all phecode
145.4 Cancer of the gums Neoplasms 1.1 0.934 – 1.31 0.246 166 1632 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.08 0.932 – 1.25 0.305 206 2048 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.06 0.998 – 1.12 0.0602 1290 12873 all phecode
149.1 Cancer of oropharynx Neoplasms 1.1 0.984 – 1.23 0.0916 350 3499 all phecode
149.2 Cancer of nasopharynx Neoplasms 1.14 0.924 – 1.4 0.226 100 1000 all phecode
149.3 Cancer of hypopharynx Neoplasms 0.992 0.777 – 1.27 0.946 82 819 all phecode
149.4 Cancer of larynx Neoplasms 1.21 1.08 – 1.35 0.000642 386 3857 all phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 1.07 0.982 – 1.17 0.118 552 5505 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.931 0.812 – 1.07 0.3 240 2398 all phecode
150 Cancer of esophagus Neoplasms 1.26 1.14 – 1.4 5.64e-06 433 4315 all phecode
151 Cancer of stomach Neoplasms 1.12 1.01 – 1.23 0.0239 498 4962 all phecode
153 Colorectal cancer Neoplasms 0.997 0.943 – 1.05 0.916 1458 14383 all phecode
153.2 Colon cancer Neoplasms 1 0.942 – 1.07 0.938 1160 11472 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.947 0.879 – 1.02 0.152 815 8093 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.08 0.981 – 1.19 0.116 511 5097 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.12 0.998 – 1.25 0.0538 344 3433 all phecode
157 Pancreatic cancer Neoplasms 0.977 0.888 – 1.07 0.626 503 5005 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.02 0.963 – 1.07 0.562 1623 15759 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.04 0.986 – 1.09 0.161 1818 17869 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.02 0.882 – 1.18 0.786 221 2206 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.992 0.838 – 1.17 0.928 158 1578 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.03 0.907 – 1.16 0.671 293 2920 all phecode
164 Cancer of intrathoracic organs Neoplasms 0.973 0.815 – 1.16 0.764 133 1324 all phecode
165 Cancer within the respiratory system Neoplasms 1.06 0.998 – 1.12 0.0581 1336 13340 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.05 0.981 – 1.12 0.164 1057 10552 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.985 0.937 – 1.04 0.548 1792 17850 all phecode
170.1 Bone cancer Neoplasms 0.977 0.906 – 1.05 0.545 773 7690 all phecode
170.2 Cancer of connective tissue Neoplasms 0.986 0.93 – 1.05 0.635 1266 12632 all phecode
172 Skin cancer Neoplasms 0.925 0.902 – 0.949 2.06e-09 8608 33186 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.904 0.877 – 0.932 1.27e-10 5330 30106 all phecode
172.11 Melanomas of skin Neoplasms 0.912 0.877 – 0.948 2.84e-06 3100 25064 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.923 0.898 – 0.949 1.58e-08 7095 30462 all phecode
172.21 Basal cell carcinoma Neoplasms 0.876 0.844 – 0.908 1.24e-12 3690 23868 all phecode
172.22 Squamous cell carcinoma Neoplasms 0.963 0.921 – 1.01 0.0966 2414 17683 all phecode
172.3 Carcinoma in situ of skin Neoplasms 0.881 0.833 – 0.932 1.07e-05 1482 12326 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.892 0.85 – 0.936 2.91e-06 1997 18755 all phecode
174 Breast cancer Neoplasms 0.893 0.858 – 0.93 3.42e-08 3186 15514 all phecode
174.1 Breast cancer [female] Neoplasms 0.891 0.855 – 0.929 4.11e-08 3036 14701 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.893 0.857 – 0.931 8.03e-08 2991 14639 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.802 0.698 – 0.921 0.00174 233 2307 all phecode
175 Acquired absence of breast Neoplasms 0.914 0.851 – 0.981 0.0129 919 8920 all phecode
180 Cervical cancer and dysplasia Neoplasms 1.02 0.965 – 1.08 0.462 1431 12185 all phecode
180.1 Cervical cancer Neoplasms 1.12 1.02 – 1.24 0.0153 500 4982 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.961 0.9 – 1.03 0.234 1048 9323 all phecode
182 Malignant neoplasm of uterus Neoplasms 1.13 1.05 – 1.23 0.00137 765 7613 all phecode
184 Cancer of other female genital organs Neoplasms 1.03 0.966 – 1.09 0.383 1191 11592 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.01 0.925 – 1.11 0.801 573 5719 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.982 0.886 – 1.09 0.731 432 4309 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.08 0.986 – 1.17 0.0997 608 6057 all phecode
185 Cancer of prostate Neoplasms 0.925 0.885 – 0.967 0.000625 2901 10342 all phecode
187 Cancer of other male genital organs Neoplasms 0.963 0.859 – 1.08 0.517 339 3384 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.13 0.93 – 1.38 0.215 115 1141 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.944 0.81 – 1.1 0.457 183 1830 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.779 0.59 – 1.03 0.0784 57 562 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.11 1.06 – 1.15 5.14e-07 2923 23541 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.13 1.07 – 1.19 2.52e-05 1450 14437 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.15 1.08 – 1.22 8.79e-06 1267 12655 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.02 0.886 – 1.17 0.779 237 2347 all phecode
189.2 Cancer of bladder Neoplasms 1.09 1.03 – 1.14 0.00179 1783 15224 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.09 1.03 – 1.15 0.00168 1657 14178 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.05 0.969 – 1.14 0.231 678 6586 all phecode
190 Cancer of eye Neoplasms 0.927 0.773 – 1.11 0.417 138 1374 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1 0.938 – 1.07 0.99 1078 10771 all phecode
191.1 Cancer of brain and nervous system Neoplasms 0.951 0.88 – 1.03 0.211 706 7052 all phecode
191.11 Cancer of brain Neoplasms 0.939 0.862 – 1.02 0.141 600 5996 all phecode
193 Thyroid cancer Neoplasms 1.02 0.954 – 1.09 0.553 945 9393 all phecode
194 Cancer of other endocrine glands Neoplasms 1.03 0.94 – 1.12 0.566 579 5759 all phecode
195 Cancer, suspected or other Neoplasms 1 0.979 – 1.02 0.982 16962 26401 all phecode
195.1 Malignant neoplasm, other Neoplasms 0.998 0.977 – 1.02 0.846 16670 26384 all phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1.03 0.969 – 1.1 0.314 1103 9766 all phecode
196 Radiotherapy Neoplasms 0.923 0.883 – 0.965 0.000396 2427 17006 all phecode
197 Chemotherapy Neoplasms 0.997 0.965 – 1.03 0.844 4952 23797 all phecode
198 Secondary malignant neoplasm Neoplasms 1.01 0.984 – 1.05 0.347 5801 23481 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.993 0.957 – 1.03 0.699 3677 21489 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.04 0.98 – 1.11 0.184 1072 10334 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1 0.934 – 1.08 0.919 866 8538 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.01 0.935 – 1.09 0.802 767 7558 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.978 0.899 – 1.06 0.593 640 6338 all phecode
198.6 Secondary malignancy of bone Neoplasms 0.997 0.927 – 1.07 0.925 866 8307 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1 0.894 – 1.13 0.948 336 3253 all phecode
199 Neoplasm of uncertain behavior Neoplasms 0.998 0.969 – 1.03 0.92 5693 25767 all phecode
199.4 Neurofibromatosis Neoplasms 0.931 0.754 – 1.15 0.502 88 880 all phecode
200 Myeloproliferative disease Neoplasms 1.05 0.988 – 1.12 0.111 1113 11098 all phecode
200.1 Polycythemia vera Neoplasms 1.12 0.974 – 1.29 0.112 231 2310 all phecode
201 Hodgkin's disease Neoplasms 1.18 1 – 1.39 0.045 172 1705 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.03 0.975 – 1.09 0.299 1559 15571 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.01 0.951 – 1.07 0.798 1329 13268 all phecode
202.21 Nodular lymphoma Neoplasms 0.974 0.899 – 1.06 0.527 693 6923 all phecode
202.22 Reticulosarcoma Neoplasms 1.14 0.972 – 1.34 0.107 170 1693 all phecode
202.24 Large cell lymphoma Neoplasms 1.11 0.937 – 1.31 0.232 160 1586 all phecode
204 Leukemia Neoplasms 1.06 0.973 – 1.15 0.189 689 6876 all phecode
204.1 Lymphoid leukemia Neoplasms 0.996 0.868 – 1.14 0.953 236 2354 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.922 0.725 – 1.17 0.503 74 734 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.984 0.836 – 1.16 0.844 173 1724 all phecode
204.2 Myeloid leukemia Neoplasms 1.11 0.976 – 1.27 0.11 265 2633 all phecode
204.21 Myeloid leukemia, acute Neoplasms 1.12 0.945 – 1.34 0.186 153 1516 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.997 0.753 – 1.32 0.983 61 610 all phecode
204.4 Multiple myeloma Neoplasms 1.14 0.99 – 1.32 0.0673 217 2162 all phecode
208 Benign neoplasm of colon Neoplasms 0.98 0.957 – 1 0.0837 10303 34953 all phecode
209 Neuroendocrine tumors Neoplasms 0.974 0.853 – 1.11 0.7 258 2580 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.974 0.928 – 1.02 0.284 1891 18839 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.09 1.06 – 1.12 1.27e-10 7329 36606 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.07 1.02 – 1.12 0.00902 1843 18412 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.994 0.944 – 1.05 0.817 1677 15527 all phecode
214 Lipoma Neoplasms 0.985 0.932 – 1.04 0.603 1437 14132 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.947 0.881 – 1.02 0.137 883 8710 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.02 0.985 – 1.05 0.31 4528 39509 all phecode
216 Benign neoplasm of skin Neoplasms 0.917 0.897 – 0.937 7.9e-15 11528 34919 all phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 0.887 0.757 – 1.04 0.139 174 1701 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.817 0.777 – 0.86 9.61e-15 1786 17184 all phecode
217.1 Nevus, non-neoplastic Neoplasms 0.813 0.771 – 0.857 1.13e-14 1679 16116 all phecode
218 Benign neoplasm of uterus Neoplasms 0.998 0.964 – 1.03 0.931 4301 16661 all phecode
218.1 Uterine leiomyoma Neoplasms 0.972 0.925 – 1.02 0.276 1835 15733 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 1 0.963 – 1.04 0.988 3403 16447 all phecode
220 Benign neoplasm of ovary Neoplasms 1.04 0.969 – 1.12 0.28 893 8783 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.01 0.963 – 1.06 0.672 2042 14248 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.901 0.846 – 0.959 0.00113 1133 10663 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.03 0.983 – 1.09 0.194 1801 12657 all phecode
224 Benign neoplasm of eye Neoplasms 0.942 0.868 – 1.02 0.15 691 6752 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.933 0.855 – 1.02 0.123 595 5773 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.05 0.988 – 1.12 0.114 1209 12074 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.04 0.973 – 1.12 0.236 947 9454 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.03 0.914 – 1.17 0.594 289 2890 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.997 0.941 – 1.06 0.921 1329 13264 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.02 0.971 – 1.08 0.391 1690 16896 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.18 1.07 – 1.31 0.000788 467 4644 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.937 0.869 – 1.01 0.0863 795 7941 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.02 0.92 – 1.13 0.724 435 4350 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.856 0.817 – 0.896 3.94e-11 2149 20946 all phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.826 0.779 – 0.876 1.72e-10 1356 13336 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.98 0.956 – 1.01 0.121 7767 36615 all phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.972 0.944 – 1 0.0549 5743 34218 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.05 0.978 – 1.12 0.191 1031 9761 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.05 1.01 – 1.09 0.0214 2910 22227 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.04 0.993 – 1.09 0.0949 2265 19902 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.06 1 – 1.13 0.0426 1304 12479 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.05 0.988 – 1.11 0.119 1400 13425 all phecode
242.1 Graves' disease Endocrine/metabolic 1.07 0.973 – 1.17 0.168 515 5068 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.05 0.87 – 1.27 0.594 124 1224 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.05 0.93 – 1.19 0.419 292 2898 all phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 1.07 0.898 – 1.28 0.439 144 1432 all phecode
244 Hypothyroidism Endocrine/metabolic 1.07 1.04 – 1.1 4.34e-07 8099 32717 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.997 0.948 – 1.05 0.911 1762 17230 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.04 0.977 – 1.1 0.232 1261 11982 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.07 1.04 – 1.1 3.49e-07 7542 32208 all phecode
245 Thyroiditis Endocrine/metabolic 1.06 0.982 – 1.14 0.14 832 7882 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.06 0.974 – 1.15 0.188 686 6517 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.05 0.964 – 1.14 0.275 679 6449 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.05 1.02 – 1.08 0.00181 6129 30240 all phecode
246.2 Thyroid cyst Endocrine/metabolic 0.9 0.732 – 1.11 0.318 101 960 all phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1.02 0.947 – 1.09 0.66 886 8696 all phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.35 1.25 – 1.45 4.55e-16 1150 8340 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.27 1.24 – 1.3 5.86e-97 13947 31815 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.29 1.21 – 1.37 1.76e-16 2364 11758 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.02 0.857 – 1.22 0.808 262 960 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.13 1.01 – 1.27 0.0385 551 2686 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.22 1.09 – 1.36 0.000427 784 3018 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.21 1.07 – 1.36 0.00168 638 2675 all phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 1.07 0.878 – 1.3 0.51 155 850 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.38 1.34 – 1.42 1.2e-126 9843 29688 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.19 1.02 – 1.4 0.0283 282 1327 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.52 1.43 – 1.61 3.6e-46 1941 13510 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.4 1.31 – 1.5 4.68e-23 1643 9668 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.5 1.42 – 1.58 1.38e-53 2557 16502 all phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.45 1.34 – 1.58 2.8e-18 860 6143 all phecode
250.3 Insulin pump user Endocrine/metabolic 1.45 1.39 – 1.52 1.09e-59 3496 20809 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.16 1.13 – 1.19 1.47e-26 8385 30645 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.11 1.05 – 1.17 9.66e-05 1870 15861 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.17 1.14 – 1.2 3.08e-26 7553 30071 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.22 1.01 – 1.48 0.0435 136 1067 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.5 1.41 – 1.59 8.54e-43 2132 13390 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.18 1.12 – 1.25 5.34e-09 1691 10517 all phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.1 1.03 – 1.18 0.0053 991 8469 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.19 1.11 – 1.28 1.36e-06 1207 8570 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.08 1.03 – 1.13 0.000722 2282 22119 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.07 1.02 – 1.12 0.0042 2088 20335 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.03 0.94 – 1.14 0.497 508 5073 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.01 0.944 – 1.09 0.69 859 8544 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.11 0.974 – 1.26 0.119 263 2621 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.18 0.938 – 1.49 0.156 83 826 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.03 0.898 – 1.18 0.673 226 2250 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.16 0.933 – 1.45 0.18 86 860 all phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 1.12 0.932 – 1.36 0.221 121 1209 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.946 0.775 – 1.15 0.581 108 1080 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.16 1.1 – 1.23 8.83e-08 1506 14869 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.05 0.946 – 1.18 0.338 373 3730 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.06 0.906 – 1.24 0.459 183 1830 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.03 0.862 – 1.23 0.734 135 1350 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.06 0.973 – 1.15 0.189 626 6239 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.06 0.97 – 1.15 0.204 596 5941 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.14 1.07 – 1.22 2.96e-05 1146 10513 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.32 1.22 – 1.43 2.66e-12 742 7128 all phecode
257 Testicular dysfunction Endocrine/metabolic 1.01 0.947 – 1.08 0.727 1015 9238 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.01 0.94 – 1.08 0.872 983 8933 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.22 0.989 – 1.51 0.0631 91 910 all phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.97 0.79 – 1.19 0.767 109 1090 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.06 0.996 – 1.14 0.0656 1038 10259 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.03 0.991 – 1.07 0.136 2880 26812 all phecode
260.1 Cachexia Endocrine/metabolic 0.946 0.836 – 1.07 0.377 292 2911 all phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.05 1 – 1.11 0.0489 1691 16847 all phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.09 1 – 1.19 0.0508 614 6140 all phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.02 0.94 – 1.11 0.593 629 6236 all phecode
260.6 Anorexia Endocrine/metabolic 1 0.931 – 1.08 0.992 868 8591 all phecode
260.7 Polyphagia Endocrine/metabolic 1.08 0.833 – 1.4 0.565 65 643 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.13 1.1 – 1.15 5.22e-19 7718 35203 all phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1.23 0.946 – 1.6 0.123 69 690 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.24 1.15 – 1.33 1.53e-08 857 8405 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.13 1.1 – 1.16 2.5e-18 7255 35225 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.02 0.755 – 1.37 0.918 52 511 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.18 1.11 – 1.26 1.01e-07 1182 11676 all phecode
263 Other nutritional deficiency Endocrine/metabolic 1.1 1.04 – 1.16 0.000425 1651 15788 all phecode
264 Lack of normal physiological development Endocrine/metabolic 0.949 0.829 – 1.09 0.452 239 2301 all phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 0.97 0.804 – 1.17 0.751 122 1220 all phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 0.881 0.702 – 1.11 0.277 81 772 all phecode
269 Proteinuria Endocrine/metabolic 1.21 1.15 – 1.28 9.49e-13 1694 13981 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.08 1.01 – 1.16 0.021 967 9575 all phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.98 0.829 – 1.16 0.813 170 1697 all phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 1.01 0.839 – 1.22 0.905 134 1334 all phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 1.22 0.985 – 1.5 0.069 96 954 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.07 0.991 – 1.16 0.0841 737 7303 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.13 1.01 – 1.26 0.0332 384 3781 all phecode
270.33 Amyloidosis Endocrine/metabolic 0.931 0.73 – 1.19 0.565 71 695 all phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 0.856 0.66 – 1.11 0.245 69 690 all phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.06 0.938 – 1.2 0.351 299 2984 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.01 0.975 – 1.06 0.484 2907 28132 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.01 0.97 – 1.05 0.624 2827 27425 all phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.05 0.862 – 1.29 0.61 102 1007 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.11 1.09 – 1.14 7.5e-24 18881 26670 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.11 1.09 – 1.14 8.06e-24 18843 26654 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.07 1.04 – 1.11 2.01e-05 5928 21600 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.13 1.07 – 1.2 3.51e-05 1360 11837 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.14 1.1 – 1.19 3.3e-11 3538 18449 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.03 0.915 – 1.16 0.614 313 3011 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.19 1.14 – 1.24 1.05e-15 2524 22729 all phecode
274.1 Gout Endocrine/metabolic 1.2 1.15 – 1.25 3.64e-16 2409 21991 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.18 1.11 – 1.26 3.62e-07 1082 10576 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.04 0.891 – 1.22 0.616 195 1890 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.05 0.897 – 1.24 0.53 183 1772 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.07 1.04 – 1.11 2.71e-05 4357 37091 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.892 0.772 – 1.03 0.121 218 2180 all phecode
275.11 Hereditary hemochromatosis Hematopoietic 0.901 0.731 – 1.11 0.331 99 990 all phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 1.08 0.834 – 1.4 0.561 62 614 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.15 1.08 – 1.22 1.46e-05 1154 11504 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.07 1.03 – 1.1 0.000711 3369 31544 all phecode
275.51 Hypocalcemia Endocrine/metabolic 1.07 0.993 – 1.14 0.0788 898 8969 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.07 1.01 – 1.14 0.0146 1366 13634 all phecode
275.6 Hypercalcemia Endocrine/metabolic 1.04 0.983 – 1.1 0.174 1468 14183 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.12 1.09 – 1.15 5.69e-21 9238 37046 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.13 1.1 – 1.17 8.14e-19 6352 34366 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.19 1.09 – 1.3 0.000152 550 5434 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.1 1.05 – 1.15 1.52e-05 2514 23219 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.18 1.13 – 1.23 1.85e-16 2992 25216 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.11 1.06 – 1.16 6.68e-06 2148 20909 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.13 1.08 – 1.18 2.74e-07 2086 20332 all phecode
276.41 Acidosis Endocrine/metabolic 1.12 1.07 – 1.18 4.34e-06 1788 17572 all phecode
276.42 Alkalosis Endocrine/metabolic 1.15 1.04 – 1.26 0.00443 476 4741 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.1 1.06 – 1.13 9.04e-09 4574 34527 all phecode
276.6 Fluid overload Endocrine/metabolic 1.26 1.19 – 1.33 6.54e-15 1384 13211 all phecode
276.8 Polydipsia Endocrine/metabolic 0.864 0.72 – 1.04 0.116 124 1240 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.14 1.1 – 1.18 7.45e-15 4112 35070 all phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.39 1.25 – 1.54 1.04e-09 403 3991 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.976 0.903 – 1.06 0.552 720 7161 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.1 1.03 – 1.18 0.00682 936 9270 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.13 1.05 – 1.22 0.00105 773 7668 all phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.36 1.26 – 1.46 2.55e-17 916 8359 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.61 1.58 – 1.64 3.72e-456 19419 27331 all phecode
278.1 Obesity Endocrine/metabolic 1.72 1.68 – 1.75 9.31e-525 17129 27321 all phecode
278.11 Morbid obesity Endocrine/metabolic 2.04 1.98 – 2.1 1.39e-524 8280 27172 all phecode
278.3 Localized adiposity Endocrine/metabolic 1.91 1.69 – 2.16 2.14e-25 324 3228 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.41 1.34 – 1.48 2.19e-44 2104 17411 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.03 0.986 – 1.07 0.203 2934 28612 all phecode
279.1 Immunity deficiency Endocrine/metabolic 0.994 0.935 – 1.06 0.86 1161 11571 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.962 0.857 – 1.08 0.508 330 3278 all phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 1.02 0.942 – 1.1 0.65 754 7516 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.01 0.975 – 1.04 0.723 4885 36552 all phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 0.989 0.907 – 1.08 0.795 601 5988 all phecode
280 Iron deficiency anemias Hematopoietic 1.13 1.09 – 1.16 3.71e-13 4626 30873 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.13 1.09 – 1.16 8.4e-13 4484 30649 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.09 1.03 – 1.14 0.000989 1771 17196 all phecode
281 Other deficiency anemia Hematopoietic 1.01 0.918 – 1.11 0.873 519 5120 all phecode
281.1 Megaloblastic anemia Hematopoietic 0.987 0.864 – 1.13 0.852 253 2497 all phecode
281.11 Pernicious anemia Hematopoietic 1.03 0.844 – 1.26 0.772 114 1108 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.975 0.835 – 1.14 0.745 187 1817 all phecode
281.9 Deficiency anemias Hematopoietic 1 0.887 – 1.14 0.944 285 2830 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.14 1.01 – 1.28 0.0332 323 3188 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.17 1.01 – 1.36 0.0365 216 2113 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.21 1.04 – 1.41 0.0149 192 1920 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.2 1.01 – 1.42 0.0367 155 1550 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.24 0.95 – 1.62 0.114 64 633 all phecode
284 Aplastic anemia Hematopoietic 1.07 0.985 – 1.16 0.111 697 6943 all phecode
284.1 Pancytopenia Hematopoietic 1.08 0.996 – 1.18 0.0633 612 6100 all phecode
285 Other anemias Hematopoietic 1.1 1.08 – 1.13 2.25e-18 11794 33591 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.11 1.07 – 1.15 1.14e-07 3325 27709 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.16 1.1 – 1.21 1.71e-09 2055 19939 all phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.22 1.14 – 1.31 9.68e-09 932 9106 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.08 0.998 – 1.18 0.055 690 6892 all phecode
286 Coagulation defects Hematopoietic 1.09 1.06 – 1.13 2.41e-07 3844 33384 all phecode
286.1 Congenital coagulation defects Hematopoietic 1.06 0.931 – 1.21 0.368 250 2466 all phecode
286.11 Von willebrand's disease Hematopoietic 1.16 0.938 – 1.44 0.168 83 822 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.03 0.857 – 1.24 0.755 126 1260 all phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.12 1.08 – 1.16 4.27e-09 3354 25918 all phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 0.964 0.775 – 1.2 0.741 97 962 all phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 1.17 1.02 – 1.33 0.0203 254 2529 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.18 0.989 – 1.4 0.0659 132 1294 all phecode
286.6 Defibrination syndrome Hematopoietic 1.1 1.06 – 1.15 4.57e-06 2579 25377 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.1 1.05 – 1.14 3.35e-06 3014 29294 all phecode
286.8 Hypercoagulable state Hematopoietic 1.05 0.98 – 1.13 0.154 846 8437 all phecode
286.81 Primary hypercoagulable state Hematopoietic 1.05 0.975 – 1.13 0.196 813 8111 all phecode
286.9 Abnormal coagulation profile Hematopoietic 1.14 1.07 – 1.21 3.43e-05 1182 11487 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.06 1.02 – 1.1 0.00176 3288 28474 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.02 0.883 – 1.17 0.823 211 2094 all phecode
287.3 Thrombocytopenia Hematopoietic 1.06 1.02 – 1.1 0.00522 2938 26323 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.06 0.971 – 1.15 0.2 601 5994 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.05 0.964 – 1.15 0.247 569 5686 all phecode
287.4 Qualitative platelet defects Hematopoietic 1.17 0.961 – 1.42 0.118 112 1120 all phecode
288 Diseases of white blood cells Hematopoietic 1.06 1.03 – 1.09 0.000138 4886 36527 all phecode
288.1 Decreased white blood cell count Hematopoietic 1 0.949 – 1.05 0.99 1599 15951 all phecode
288.11 Neutropenia Hematopoietic 1.01 0.944 – 1.07 0.862 1106 11041 all phecode
288.2 Elevated white blood cell count Hematopoietic 1.07 1.04 – 1.11 3.33e-05 4082 35079 all phecode
288.3 Eosinophilia Hematopoietic 0.85 0.728 – 0.992 0.0394 187 1866 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.05 0.996 – 1.1 0.0737 1757 17434 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.02 0.951 – 1.09 0.579 918 9087 all phecode
289.4 Lymphadenitis Hematopoietic 1.04 1.01 – 1.08 0.0132 3888 34715 all phecode
289.5 Diseases of spleen Hematopoietic 1.06 0.95 – 1.18 0.303 393 3913 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.09 0.956 – 1.24 0.201 255 2550 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.13 1.01 – 1.26 0.0297 385 3813 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.03 0.968 – 1.09 0.38 1318 11547 all phecode
290.1 Dementias Mental Disorders 0.975 0.889 – 1.07 0.584 541 4910 all phecode
290.11 Alzheimer's disease Mental Disorders 1.01 0.849 – 1.21 0.889 151 1389 all phecode
290.12 Dementia with cerebral degenerations Mental Disorders 1.04 0.832 – 1.31 0.712 88 846 all phecode
290.13 Senile dementia Mental Disorders 0.982 0.873 – 1.1 0.758 340 3078 all phecode
290.16 Vascular dementia Mental Disorders 1.03 0.819 – 1.3 0.781 81 777 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.04 0.959 – 1.12 0.364 750 7358 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.929 0.865 – 0.997 0.0413 886 8618 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.01 0.971 – 1.06 0.562 2550 24810 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.921 0.786 – 1.08 0.307 175 1750 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.962 0.875 – 1.06 0.431 484 4807 all phecode
291.8 Alteration of consciousness Mental Disorders 1.03 0.979 – 1.08 0.279 2036 19974 all phecode
292 Neurological disorders Mental Disorders 1.02 0.988 – 1.05 0.263 5733 38553 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.996 0.95 – 1.04 0.863 2013 19867 all phecode
292.11 Aphasia Mental Disorders 0.997 0.918 – 1.08 0.942 664 6581 all phecode
292.12 Symbolic dysfunction Mental Disorders 1.06 0.913 – 1.23 0.455 200 1988 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.967 0.868 – 1.08 0.544 389 3731 all phecode
292.3 Memory loss Mental Disorders 0.956 0.911 – 1 0.0653 1922 18158 all phecode
292.4 Altered mental status Mental Disorders 1.07 1.03 – 1.12 0.00133 2454 22725 all phecode
292.5 Transient alteration of awareness Mental Disorders 0.99 0.897 – 1.09 0.84 430 4285 all phecode
292.6 Hallucinations Mental Disorders 1.12 0.975 – 1.3 0.108 217 2147 all phecode
293 Symptoms involving head and neck Mental Disorders 0.915 0.826 – 1.01 0.0877 414 4127 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.03 0.993 – 1.06 0.12 4417 38609 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.05 0.976 – 1.13 0.196 885 8229 all phecode
295.1 Schizophrenia Mental Disorders 0.888 0.742 – 1.06 0.195 138 1339 all phecode
295.2 Paranoid disorders Mental Disorders 1.11 0.918 – 1.35 0.274 118 1079 all phecode
295.3 Psychosis Mental Disorders 1.07 0.993 – 1.16 0.0759 716 6694 all phecode
296 Mood disorders Mental Disorders 1.08 1.06 – 1.11 6.21e-13 15356 20858 all phecode
296.1 Bipolar Mental Disorders 1.13 1.07 – 1.2 5.37e-05 1301 11264 all phecode
296.2 Depression Mental Disorders 1.09 1.06 – 1.11 3.81e-13 14833 20856 all phecode
296.22 Major depressive disorder Mental Disorders 1.09 1.06 – 1.11 5.98e-13 13850 20853 all phecode
297 Suicidal ideation or attempt Mental Disorders 1.11 1.04 – 1.19 0.00284 985 9050 all phecode
297.1 Suicidal ideation Mental Disorders 1.1 1.02 – 1.18 0.0155 788 7310 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.05 0.93 – 1.19 0.415 285 2654 all phecode
300 Anxiety disorders Mental Disorders 1.05 1.03 – 1.08 2.19e-06 15419 20850 all phecode
300.1 Anxiety disorder Mental Disorders 1.06 1.03 – 1.08 8.13e-07 14517 20855 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1.04 1 – 1.07 0.0255 5546 20512 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.04 0.979 – 1.1 0.211 1360 11377 all phecode
300.13 Phobia Mental Disorders 1.07 0.998 – 1.14 0.0554 1051 9542 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.954 0.849 – 1.07 0.424 328 3018 all phecode
300.4 Dysthymic disorder Mental Disorders 1.06 1.01 – 1.1 0.0182 2420 16552 all phecode
300.8 Acute reaction to stress Mental Disorders 1.06 0.962 – 1.17 0.239 504 4825 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.12 1.04 – 1.21 0.00203 843 7909 all phecode
301 Personality disorders Mental Disorders 1.12 1.02 – 1.24 0.0201 477 4539 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.04 0.913 – 1.19 0.53 254 2393 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.968 0.932 – 1.01 0.0936 3700 13808 all phecode
302.1 Decreased libido Mental Disorders 0.92 0.833 – 1.02 0.0995 447 4331 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.927 0.9 – 0.954 2.65e-07 6808 20043 all phecode
303.1 Dissociative disorder Mental Disorders 1.29 1.08 – 1.53 0.00399 161 1573 all phecode
303.3 Psychogenic disorder Mental Disorders 0.916 0.89 – 0.944 8.25e-09 6487 19888 all phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.927 0.84 – 1.02 0.134 471 4623 all phecode
303.4 Somatoform disorder Mental Disorders 1 0.944 – 1.07 0.884 1177 11180 all phecode
304 Adjustment reaction Mental Disorders 1.02 0.985 – 1.06 0.248 3888 20475 all phecode
305.2 Eating disorder Mental Disorders 1.31 1.22 – 1.4 1.45e-13 901 8329 all phecode
306 Other mental disorder Mental Disorders 1.04 0.984 – 1.09 0.178 1815 14133 all phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.09 0.99 – 1.19 0.0796 587 3527 all phecode
306.9 Tension headache Mental Disorders 1.03 0.948 – 1.11 0.533 753 7277 all phecode
312 Conduct disorders Mental Disorders 1.12 0.983 – 1.27 0.0883 254 2501 all phecode
312.3 Impulse control disorder Mental Disorders 1.1 0.872 – 1.38 0.426 74 736 all phecode
313 Pervasive developmental disorders Mental Disorders 1.04 0.985 – 1.09 0.159 1571 14633 all phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1.03 0.977 – 1.09 0.258 1392 13190 all phecode
313.2 Tics and stuttering Mental Disorders 1.16 0.922 – 1.46 0.204 77 770 all phecode
313.3 Autism Mental Disorders 0.953 0.736 – 1.23 0.716 64 621 all phecode
315 Develomental delays and disorders Mental Disorders 1.09 1 – 1.18 0.0414 684 6788 all phecode
315.1 Learning disorder Mental Disorders 1.17 0.946 – 1.45 0.147 87 860 all phecode
315.2 Speech and language disorder Mental Disorders 0.944 0.826 – 1.08 0.39 254 2539 all phecode
316 Substance addiction and disorders Mental Disorders 1.12 1.08 – 1.16 9.63e-11 3682 32680 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.01 0.926 – 1.09 0.879 634 6331 all phecode
317 Alcohol-related disorders Mental Disorders 1.03 0.988 – 1.07 0.157 2525 22920 all phecode
317.1 Alcoholism Mental Disorders 1.02 0.976 – 1.07 0.339 1986 19339 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.02 0.917 – 1.13 0.748 408 4080 all phecode
318 Tobacco use disorder Mental Disorders 1.19 1.16 – 1.22 7.86e-43 8622 34842 all phecode
320 Meningitis Neurological 1.04 0.936 – 1.16 0.444 382 3820 all phecode
323 Encephalitis Neurological 1.07 0.92 – 1.25 0.372 181 1809 all phecode
323.8 Encephalitis, non-infectious Neurological 1.07 0.904 – 1.26 0.447 153 1527 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.12 0.989 – 1.27 0.0733 288 2880 all phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 0.965 0.73 – 1.27 0.8 53 530 all phecode
327 Sleep disorders Neurological 1.18 1.16 – 1.2 3.14e-57 14941 31602 all phecode
327.1 Hypersomnia Neurological 1.1 1.05 – 1.15 7.52e-05 2061 19110 all phecode
327.3 Sleep apnea Neurological 1.26 1.24 – 1.29 1.96e-88 10909 31304 all phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1.05 0.956 – 1.15 0.308 492 4784 all phecode
327.32 Obstructive sleep apnea Neurological 1.27 1.24 – 1.3 5.73e-78 8744 30530 all phecode
327.4 Insomnia Neurological 1.06 1.03 – 1.1 3.91e-05 5524 30960 all phecode
327.41 Organic or persistent insomnia Neurological 1.01 0.947 – 1.07 0.862 1265 12120 all phecode
327.5 Parasomnia Neurological 1.15 1.06 – 1.25 0.00105 604 5913 all phecode
327.6 Circadian rhythm sleep disorder Neurological 1.06 0.931 – 1.2 0.388 274 2666 all phecode
327.7 Sleep related movement disorders Neurological 1.15 1.1 – 1.21 2.94e-08 1786 17323 all phecode
327.71 Restless legs syndrome Neurological 1.17 1.11 – 1.23 1.99e-08 1570 15360 all phecode
327.72 Sleep related leg cramps Neurological 1.06 0.841 – 1.33 0.625 83 822 all phecode
331 Other cerebral degenerations Neurological 0.918 0.848 – 0.993 0.033 717 7024 all phecode
331.1 Hydrocephalus Neurological 0.932 0.825 – 1.05 0.26 284 2836 all phecode
331.9 Cerebral degeneration, unspecified Neurological 0.934 0.843 – 1.04 0.196 419 4026 all phecode
332 Parkinson's disease Neurological 0.873 0.787 – 0.968 0.00969 415 4128 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.05 1.01 – 1.09 0.0213 2868 26583 all phecode
333.1 Essential tremor Neurological 0.957 0.884 – 1.03 0.269 725 7163 all phecode
333.2 Myoclonus Neurological 1.19 1.01 – 1.4 0.0333 159 1590 all phecode
333.4 Torsion dystonia Neurological 0.852 0.762 – 0.954 0.00548 352 3504 all phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 0.856 0.69 – 1.06 0.161 89 890 all phecode
334 Degenerative disease of the spinal cord Neurological 1.08 1.01 – 1.15 0.0301 1058 10562 all phecode
334.1 Spinocerebellar disease Neurological 1.09 0.856 – 1.38 0.499 79 790 all phecode
334.2 Anterior horn cell disease Neurological 0.997 0.815 – 1.22 0.973 110 1080 all phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 0.938 0.732 – 1.2 0.611 71 693 all phecode
335 Multiple sclerosis Neurological 1.1 0.988 – 1.22 0.0832 396 3951 all phecode
337 Disorders of the autonomic nervous system Neurological 0.999 0.928 – 1.07 0.971 808 7413 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.07 0.961 – 1.19 0.216 370 3164 all phecode
338 Pain Neurological 1.08 1.06 – 1.1 2.88e-14 20346 26417 all phecode
338.1 Acute pain Neurological 1.06 1.04 – 1.09 3.53e-09 15582 26313 all phecode
338.2 Chronic pain Neurological 1.12 1.09 – 1.15 5.29e-22 10994 26368 all phecode
339 Other headache syndromes Neurological 1.04 1.02 – 1.07 0.000854 9242 34658 all phecode
340 Migraine Neurological 1.05 1.02 – 1.08 0.00112 6708 30587 all phecode
340.1 Migrain with aura Neurological 1.04 0.999 – 1.07 0.055 3624 23684 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.18 0.985 – 1.41 0.0722 133 1330 all phecode
342 Hemiplegia Neurological 1.03 0.933 – 1.13 0.578 464 4607 all phecode
343 Infantile cerebral palsy Neurological 1.07 0.853 – 1.33 0.575 85 847 all phecode
344 Other paralytic syndromes Neurological 1.05 0.968 – 1.14 0.242 682 6808 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.04 0.995 – 1.08 0.0856 2553 25307 all phecode
345.1 Epilepsy Neurological 1 0.931 – 1.08 0.902 747 7465 all phecode
345.11 Generalized convulsive epilepsy Neurological 1.02 0.887 – 1.16 0.822 233 2330 all phecode
345.12 Partial epilepsy Neurological 1.01 0.924 – 1.11 0.815 534 5335 all phecode
345.3 Convulsions Neurological 1.04 0.999 – 1.09 0.0561 2396 23796 all phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.98 0.842 – 1.14 0.788 183 1824 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.01 0.958 – 1.07 0.659 1472 14587 all phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.864 0.718 – 1.04 0.122 120 1181 all phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 0.88 0.72 – 1.08 0.213 110 1100 all phecode
347 Cataplexy and narcolepsy Neurological 1.08 0.88 – 1.34 0.449 101 1010 all phecode
348 Other conditions of brain Neurological 1.06 1.01 – 1.11 0.0199 1793 17894 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.04 0.97 – 1.11 0.278 905 9034 all phecode
348.4 Cerebral cysts Neurological 0.965 0.839 – 1.11 0.617 229 2290 all phecode
348.7 Coma Neurological 0.951 0.829 – 1.09 0.469 229 2275 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.09 1.02 – 1.18 0.0168 853 8479 all phecode
348.9 Other conditions of brain, NOS Neurological 1 0.96 – 1.05 0.911 2341 23287 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.06 0.987 – 1.13 0.11 941 9385 all phecode
350 Abnormal movement Neurological 1.03 0.999 – 1.05 0.0641 6706 38762 all phecode
350.1 Abnormal involuntary movements Neurological 1.03 0.992 – 1.07 0.118 3273 30524 all phecode
350.2 Abnormality of gait Neurological 1.02 0.989 – 1.06 0.177 3920 30520 all phecode
350.3 Lack of coordination Neurological 0.964 0.904 – 1.03 0.265 1062 10554 all phecode
350.5 Abnormal reflex Neurological 1.01 0.871 – 1.17 0.898 200 1988 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.974 0.891 – 1.06 0.557 558 5576 all phecode
351 Other peripheral nerve disorders Neurological 1.09 1.06 – 1.12 3.35e-10 7401 34460 all phecode
352 Disorders of other cranial nerves Neurological 1.03 0.978 – 1.08 0.274 1714 17106 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1 0.915 – 1.1 0.944 535 5344 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.07 0.995 – 1.16 0.0691 783 7826 all phecode
353 Nerve root and plexus disorders Neurological 1.07 1.03 – 1.1 0.000125 4256 33369 all phecode
353.1 Nerve plexus lesions Neurological 1.06 0.95 – 1.18 0.302 390 3900 all phecode
353.2 Nerve root lesions Neurological 1.07 0.891 – 1.29 0.459 130 1287 all phecode
355 Complex regional/central pain syndrome Neurological 1.04 0.945 – 1.14 0.456 531 5295 all phecode
355.1 Chronic pain syndrome Neurological 1.16 1.08 – 1.24 9.45e-05 843 8386 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.05 1.01 – 1.1 0.0184 2335 20731 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.09 1.05 – 1.13 9.63e-06 3472 29956 all phecode
358 Myoneural disorders Neurological 1.1 1.04 – 1.17 0.00223 1147 11391 all phecode
358.1 Myasthenia gravis Neurological 0.877 0.715 – 1.07 0.206 109 1082 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.945 0.887 – 1.01 0.0786 1134 11274 all phecode
359.1 Muscular dystrophies Neurological 0.909 0.686 – 1.2 0.505 64 632 all phecode
359.2 Myopathy Neurological 0.949 0.89 – 1.01 0.114 1092 10843 all phecode
360 Disorders of the globe Sense Organs 0.873 0.725 – 1.05 0.149 131 1276 all phecode
360.2 Progressive myopia Sense Organs 0.787 0.605 – 1.02 0.0735 65 640 all phecode
361 Retinal detachments and defects Sense Organs 0.927 0.857 – 1 0.0605 733 7131 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.865 0.765 – 0.978 0.0211 302 2962 all phecode
362 Other retinal disorders Sense Organs 0.97 0.935 – 1.01 0.116 3569 22997 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.949 0.905 – 0.995 0.0296 2172 15483 all phecode
362.21 Macular degeneration, dry Sense Organs 0.871 0.78 – 0.971 0.0132 419 3438 all phecode
362.22 Macular degeneration, wet Sense Organs 0.909 0.759 – 1.09 0.295 148 1184 all phecode
362.23 Cystoid macular degeneration of retina Sense Organs 0.873 0.786 – 0.971 0.0125 408 3839 all phecode
362.26 Macular puckering of retina Sense Organs 0.918 0.857 – 0.983 0.0138 976 8610 all phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.895 0.812 – 0.987 0.0264 488 4558 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.954 0.907 – 1 0.0703 1883 13955 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.02 0.949 – 1.09 0.639 976 8527 all phecode
362.31 Separation of retinal layers Sense Organs 0.936 0.844 – 1.04 0.21 413 4056 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.966 0.888 – 1.05 0.41 662 5933 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.919 0.825 – 1.02 0.122 392 3787 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.969 0.839 – 1.12 0.665 215 2103 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.05 0.916 – 1.2 0.489 241 2368 all phecode
362.9 Retinal edema Sense Organs 1.12 0.992 – 1.25 0.0676 324 2936 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.929 0.844 – 1.02 0.133 492 4746 all phecode
363.3 Chorioretinal scars Sense Organs 0.864 0.77 – 0.968 0.012 332 3184 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.944 0.885 – 1.01 0.0751 1132 10772 all phecode
364.1 Corneal opacity Sense Organs 0.957 0.862 – 1.06 0.416 394 3846 all phecode
364.2 Corneal edema Sense Organs 1.08 0.898 – 1.3 0.408 123 1208 all phecode
364.4 Corneal degenerations Sense Organs 0.94 0.847 – 1.04 0.25 402 3962 all phecode
364.41 Keratoconus Sense Organs 0.798 0.625 – 1.02 0.0716 75 739 all phecode
364.5 Corneal dystrophy Sense Organs 0.942 0.855 – 1.04 0.226 502 4682 all phecode
364.51 Fuchs' dystrophy Sense Organs 0.888 0.777 – 1.02 0.0819 266 2521 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.881 0.705 – 1.1 0.262 91 885 all phecode
365 Glaucoma Sense Organs 0.942 0.904 – 0.983 0.00568 2672 21326 all phecode
365.1 Open-angle glaucoma Sense Organs 0.901 0.831 – 0.976 0.0109 705 6491 all phecode
365.11 Primary open angle glaucoma Sense Organs 0.866 0.778 – 0.964 0.00824 403 3681 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.92 0.802 – 1.05 0.231 251 2370 all phecode
366 Cataract Sense Organs 0.967 0.941 – 0.993 0.0142 8611 28043 all phecode
366.1 Nonsenile Cataract Sense Organs 0.885 0.764 – 1.03 0.105 207 1979 all phecode
366.2 Senile cataract Sense Organs 0.95 0.92 – 0.981 0.00168 5480 24980 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.96 0.937 – 0.983 0.000908 8967 37779 all phecode
367.1 Myopia Sense Organs 0.943 0.914 – 0.972 0.000192 5014 34677 all phecode
367.2 Astigmatism Sense Organs 0.93 0.899 – 0.962 2.55e-05 4161 32463 all phecode
367.8 Hypermetropia Sense Organs 0.933 0.889 – 0.978 0.00377 2039 18599 all phecode
367.9 Blindness and low vision Sense Organs 1.04 0.977 – 1.1 0.234 1277 12356 all phecode
368 Visual disturbances Sense Organs 0.994 0.966 – 1.02 0.689 5715 39599 all phecode
368.1 Amblyopia Sense Organs 1.02 0.934 – 1.1 0.72 651 6479 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.985 0.924 – 1.05 0.651 1087 10786 all phecode
368.3 Anisometropia Sense Organs 0.877 0.761 – 1.01 0.073 219 2168 all phecode
368.4 Visual field defects Sense Organs 0.99 0.93 – 1.05 0.765 1132 11173 all phecode
368.9 Subjective visual disturbances Sense Organs 1.03 0.964 – 1.1 0.404 1070 10620 all phecode
368.91 Psychophysical visual disturbances Sense Organs 1.23 1.01 – 1.49 0.038 120 1171 all phecode
369 Infection of the eye Sense Organs 0.944 0.909 – 0.98 0.00272 3185 28240 all phecode
369.2 Eye infection, viral Sense Organs 0.93 0.845 – 1.02 0.135 502 4954 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.944 0.906 – 0.983 0.0058 2716 24970 all phecode
370 Keratitis Sense Organs 0.929 0.877 – 0.983 0.0112 1365 13169 all phecode
370.1 Corneal ulcer Sense Organs 0.932 0.812 – 1.07 0.321 223 2194 all phecode
370.2 Superficial keratitis Sense Organs 0.884 0.809 – 0.967 0.00702 546 5393 all phecode
370.3 Keratoconjunctivitis Sense Organs 1 0.92 – 1.09 0.998 649 6263 all phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.935 0.796 – 1.1 0.416 179 1677 all phecode
371 Inflammation of the eye Sense Organs 0.942 0.912 – 0.974 0.000381 4414 32310 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.979 0.894 – 1.07 0.638 541 5278 all phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.956 0.891 – 1.03 0.207 906 8939 all phecode
371.21 Allergic conjunctivitis Sense Organs 0.94 0.87 – 1.01 0.111 756 7515 all phecode
371.3 Inflammation of eyelids Sense Organs 0.929 0.895 – 0.964 9.4e-05 3398 26983 all phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 0.868 0.72 – 1.05 0.138 133 1291 all phecode
372 Disorders of conjunctiva Sense Organs 0.935 0.878 – 0.996 0.0378 1118 10728 all phecode
374 Other disorders of eyelids Sense Organs 0.935 0.898 – 0.973 0.000882 2940 24188 all phecode
374.1 Ectropion or entropion Sense Organs 0.884 0.798 – 0.98 0.019 431 4084 all phecode
374.2 Lagophthalmos Sense Organs 1.05 0.918 – 1.21 0.454 235 2335 all phecode
374.3 Ptosis of eyelid Sense Organs 0.942 0.883 – 1 0.0684 1102 10734 all phecode
374.6 Dermatochalasis Sense Organs 0.984 0.921 – 1.05 0.642 1040 9720 all phecode
375 Disorders of lacrimal system Sense Organs 0.956 0.922 – 0.991 0.0153 3694 26045 all phecode
375.1 Dry eyes Sense Organs 0.956 0.923 – 0.99 0.0111 4040 26751 all phecode
375.2 Epiphora Sense Organs 0.925 0.835 – 1.02 0.133 442 4354 all phecode
376 Disorders of the orbit Sense Organs 1.05 0.936 – 1.17 0.425 352 3508 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.02 0.955 – 1.1 0.507 913 9021 all phecode
377.1 Optic atrophy Sense Organs 0.945 0.832 – 1.07 0.388 283 2793 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.03 0.948 – 1.13 0.449 585 5775 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.961 0.906 – 1.02 0.195 1275 12460 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.964 0.895 – 1.04 0.332 828 8130 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.01 0.858 – 1.18 0.944 170 1686 all phecode
378.5 Paralytic strabismus Sense Organs 0.894 0.798 – 1 0.0518 349 3437 all phecode
379 Other disorders of eye Sense Organs 0.939 0.909 – 0.969 9.04e-05 5046 29999 all phecode
379.1 Scleritis and episcleritis Sense Organs 0.86 0.732 – 1.01 0.0646 176 1743 all phecode
379.2 Disorders of vitreous body Sense Organs 0.926 0.892 – 0.961 4.76e-05 3634 23186 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.821 0.687 – 0.982 0.0309 135 1258 all phecode
379.4 Anomalies of pupillary function Sense Organs 0.894 0.79 – 1.01 0.0788 287 2833 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.05 0.936 – 1.19 0.389 304 2948 all phecode
379.51 Pigmentary iris degeneration Sense Organs 1.02 0.795 – 1.3 0.89 77 731 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.982 0.921 – 1.05 0.568 1129 11130 all phecode
380 Disorders of external ear Sense Organs 0.89 0.851 – 0.931 3.76e-07 2242 20393 all phecode
380.1 Otitis externa Sense Organs 0.98 0.928 – 1.04 0.477 1469 14580 all phecode
380.4 Impacted cerumen Sense Organs 0.887 0.851 – 0.925 1.73e-08 2648 23557 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.01 0.973 – 1.04 0.75 4255 36417 all phecode
381.1 Otitis media Sense Organs 1.05 1.01 – 1.09 0.0102 3079 29813 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.06 1.01 – 1.1 0.00822 2610 25602 all phecode
381.2 Eustachian tube disorders Sense Organs 0.925 0.88 – 0.972 0.00207 1816 17827 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.11 0.939 – 1.31 0.222 153 1530 all phecode
381.9 Otorrhea Sense Organs 1.06 0.951 – 1.18 0.3 372 3713 all phecode
382 Otalgia Sense Organs 1.03 0.983 – 1.08 0.209 1884 18673 all phecode
383 Otosclerosis Sense Organs 0.936 0.774 – 1.13 0.495 124 1240 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.03 0.941 – 1.13 0.504 516 5156 all phecode
384.1 Myringitis Sense Organs 0.942 0.707 – 1.26 0.685 51 502 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.03 0.931 – 1.14 0.547 403 4029 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.02 0.919 – 1.12 0.763 432 4320 all phecode
385.3 Cholesteatoma Sense Organs 1.03 0.913 – 1.17 0.597 277 2770 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.01 0.839 – 1.22 0.891 118 1180 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.994 0.947 – 1.04 0.82 1882 18186 all phecode
386.1 Meniere's disease Sense Organs 0.975 0.866 – 1.1 0.671 319 3156 all phecode
386.2 Peripheral or central vertigo Sense Organs 0.998 0.946 – 1.05 0.954 1586 15423 all phecode
386.21 Central origin vertigo Sense Organs 1.01 0.949 – 1.07 0.771 1208 11844 all phecode
386.3 Labyrinthitis Sense Organs 1 0.949 – 1.06 0.93 1482 14530 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.01 0.988 – 1.04 0.287 6933 38286 all phecode
388 Other disorders of ear Sense Organs 0.972 0.908 – 1.04 0.417 960 9501 all phecode
389 Hearing loss Sense Organs 0.981 0.957 – 1.01 0.134 8182 38069 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.927 0.896 – 0.959 1.36e-05 4107 29258 all phecode
389.2 Conductive hearing loss Sense Organs 0.97 0.905 – 1.04 0.387 905 9042 all phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.943 0.811 – 1.1 0.449 192 1808 all phecode
389.4 Tinnitus Sense Organs 0.919 0.879 – 0.96 0.000168 2291 22130 all phecode
389.5 Disorders of acoustic nerve Sense Organs 1.01 0.839 – 1.22 0.906 124 1229 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.06 1 – 1.12 0.0423 1458 13732 all phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 1.06 0.95 – 1.19 0.283 350 3415 all phecode
394.2 Mitral valve disease Circulatory System 1.06 0.957 – 1.16 0.276 462 4560 all phecode
394.3 Aortic valve disease Circulatory System 1.02 0.869 – 1.2 0.795 176 1691 all phecode
394.4 Acute rheumatic heart disease Circulatory System 1.14 0.86 – 1.5 0.367 55 546 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.06 0.974 – 1.16 0.172 587 5739 all phecode
395 Heart valve disorders Circulatory System 1.02 0.986 – 1.06 0.247 3976 28748 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.961 0.918 – 1.01 0.0862 2175 20441 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.09 1.04 – 1.15 0.000226 2060 17194 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.05 0.957 – 1.16 0.289 493 4864 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.998 0.815 – 1.22 0.983 108 1080 all phecode
395.6 Heart valve replaced Circulatory System 1.12 1.05 – 1.19 0.000633 1177 10833 all phecode
396 Abnormal heart sounds Circulatory System 0.992 0.962 – 1.02 0.635 4718 34395 all phecode
401 Hypertension Circulatory System 1.31 1.28 – 1.34 2.11e-131 23317 23367 all phecode
401.1 Essential hypertension Circulatory System 1.31 1.28 – 1.34 7.37e-133 23158 23364 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.44 1.38 – 1.5 1.19e-65 3503 14616 all phecode
401.21 Hypertensive heart disease Circulatory System 1.4 1.3 – 1.5 1.53e-18 893 6607 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.43 1.36 – 1.49 5.22e-50 2584 13072 all phecode
401.3 Other hypertensive complications Circulatory System 1.31 1.25 – 1.37 4.72e-33 2679 15833 all phecode
411 Ischemic Heart Disease Circulatory System 1.18 1.15 – 1.21 4.11e-35 8807 30299 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.18 1.1 – 1.26 5.48e-06 937 8574 all phecode
411.2 Myocardial infarction Circulatory System 1.24 1.19 – 1.28 6.72e-29 3594 21716 all phecode
411.3 Angina pectoris Circulatory System 1.19 1.14 – 1.24 3.79e-15 2485 18304 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.18 1.15 – 1.22 8.13e-32 7555 27492 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.16 0.979 – 1.38 0.086 156 1529 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.2 1.17 – 1.24 9.69e-34 6331 25741 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.21 1.09 – 1.33 0.000254 442 4211 all phecode
414 Other forms of chronic heart disease Circulatory System 1.12 1.08 – 1.16 1.24e-08 3101 22616 all phecode
414.2 ASCVD Circulatory System 1.11 1.03 – 1.2 0.00796 718 6816 all phecode
415 Pulmonary heart disease Circulatory System 1.16 1.12 – 1.21 1.62e-15 3366 30208 all phecode
415.1 Acute pulmonary heart disease Circulatory System 1.14 1.09 – 1.2 1.5e-07 1912 19014 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.14 1.09 – 1.2 1.17e-07 1906 18953 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.18 1.12 – 1.24 7.51e-11 1808 17605 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.13 1.05 – 1.23 0.00188 706 7032 all phecode
416 Cardiomegaly Circulatory System 1.09 1.03 – 1.16 0.00401 1254 12372 all phecode
418 Nonspecific chest pain Circulatory System 1.05 1.03 – 1.07 2.73e-06 12650 33952 all phecode
418.1 Precordial pain Circulatory System 1.04 0.986 – 1.1 0.139 1471 13782 all phecode
420 Carditis Circulatory System 1.08 1.03 – 1.14 0.00356 1588 15680 all phecode
420.1 Myocarditis Circulatory System 1.18 0.944 – 1.46 0.148 97 958 all phecode
420.2 Pericarditis Circulatory System 1.06 0.987 – 1.14 0.109 842 8402 all phecode
420.21 Acute pericarditis Circulatory System 1.14 0.977 – 1.33 0.0947 177 1764 all phecode
420.22 Chronic pericarditis Circulatory System 1.27 1.04 – 1.55 0.0198 117 1153 all phecode
420.3 Endocarditis Circulatory System 1.13 1.04 – 1.22 0.00218 764 7535 all phecode
425 Cardiomyopathy Circulatory System 1.14 1.09 – 1.19 6.91e-08 2078 19881 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.15 1.09 – 1.2 1.86e-08 1989 19025 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.07 0.923 – 1.24 0.38 208 2050 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.11 0.961 – 1.29 0.152 201 1992 all phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.04 0.926 – 1.17 0.49 317 3170 all phecode
425.8 Other cardiomyopathy Circulatory System 0.986 0.785 – 1.24 0.906 95 931 all phecode
426 Cardiac conduction disorders Circulatory System 1.08 1.06 – 1.11 8.15e-11 12327 25440 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.12 1.07 – 1.18 7.28e-06 1903 11501 all phecode
426.21 First degree AV block Circulatory System 1.1 1.04 – 1.17 0.00198 1313 8899 all phecode
426.22 Mobitz II AV block Circulatory System 0.943 0.717 – 1.24 0.674 64 553 all phecode
426.23 Second degree AV block Circulatory System 0.971 0.84 – 1.12 0.696 216 1925 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.07 0.97 – 1.19 0.175 461 3823 all phecode
426.25 Other heart block Circulatory System 1.02 0.881 – 1.18 0.779 203 1803 all phecode
426.3 Bundle branch block Circulatory System 1.07 1.02 – 1.12 0.00306 2306 13999 all phecode
426.31 Right bundle branch block Circulatory System 1.07 1.01 – 1.14 0.0166 1423 10758 all phecode
426.32 Left bundle branch block Circulatory System 1.09 1.02 – 1.17 0.01 969 8110 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.988 0.791 – 1.23 0.917 82 820 all phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.08 1.05 – 1.11 7.52e-10 10577 25186 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.06 0.981 – 1.15 0.136 679 6650 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.1 1.04 – 1.16 0.000476 1754 11536 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.11 1.04 – 1.19 0.00102 1171 8184 all phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.11 1.04 – 1.2 0.00387 846 7320 all phecode
427 Cardiac dysrhythmias Circulatory System 1.05 1.03 – 1.07 1.99e-06 17397 25735 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.04 0.999 – 1.09 0.056 2474 18178 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.04 0.984 – 1.09 0.177 1595 14293 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.08 1.01 – 1.14 0.0219 1181 9915 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.1 1.06 – 1.13 9.8e-08 5313 18688 all phecode
427.21 Atrial fibrillation Circulatory System 1.09 1.06 – 1.13 1.95e-07 5188 18409 all phecode
427.22 Atrial flutter Circulatory System 1.06 1.01 – 1.12 0.0283 1693 11042 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.05 1.03 – 1.08 0.000102 8688 25552 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.05 0.96 – 1.15 0.278 536 5233 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.89 0.771 – 1.03 0.113 216 2118 all phecode
427.42 Cardiac arrest Circulatory System 1.14 1.03 – 1.26 0.0141 410 4034 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.04 1.01 – 1.07 0.00414 6905 25457 all phecode
427.6 Premature beats Circulatory System 1.02 0.978 – 1.07 0.332 2359 16248 all phecode
427.61 Supraventricular premature beats Circulatory System 1.05 0.968 – 1.14 0.236 670 6287 all phecode
427.7 Tachycardia NOS Circulatory System 1.09 1.05 – 1.12 9.15e-08 5124 25531 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.06 0.984 – 1.13 0.132 912 7501 all phecode
427.9 Palpitations Circulatory System 0.98 0.948 – 1.01 0.236 4430 24505 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.23 1.19 – 1.27 1.18e-31 4300 23663 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.24 1.2 – 1.29 1.07e-30 3756 22446 all phecode
428.2 Heart failure NOS Circulatory System 1.27 1.22 – 1.32 1.2e-35 3701 21722 all phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.22 1.16 – 1.29 1.28e-14 1765 14476 all phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.31 1.24 – 1.38 1.25e-22 1648 13395 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.07 1.04 – 1.09 3.22e-09 12635 32504 all phecode
429.1 Heart transplant/surgery Circulatory System 1.08 1.02 – 1.15 0.0146 1219 11696 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.1 1.07 – 1.14 3.22e-11 6322 29232 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.05 1.03 – 1.08 1.61e-05 9650 32421 all phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.1 1.02 – 1.19 0.0155 723 7072 all phecode
430 Intracranial hemorrhage Circulatory System 0.931 0.863 – 1 0.061 789 7842 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.933 0.818 – 1.06 0.3 261 2610 all phecode
430.2 Intracerebral hemorrhage Circulatory System 0.965 0.864 – 1.08 0.521 368 3671 all phecode
430.3 Subdural hemorrhage Circulatory System 0.833 0.734 – 0.945 0.00451 272 2680 all phecode
433 Cerebrovascular disease Circulatory System 1.09 1.05 – 1.12 6.6e-08 5463 32242 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.1 1.04 – 1.15 0.000245 1978 16212 all phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.18 1.03 – 1.35 0.016 260 2517 all phecode
433.12 Cerebral atherosclerosis Circulatory System 0.989 0.783 – 1.25 0.923 80 789 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.09 1.05 – 1.14 4.2e-05 2437 21732 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.09 1.05 – 1.14 5.17e-05 2357 21103 all phecode
433.3 Cerebral ischemia Circulatory System 1.05 1.01 – 1.1 0.0159 2780 22868 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.07 1.03 – 1.12 0.00185 2409 20762 all phecode
433.5 Cerebral aneurysm Circulatory System 1.06 0.958 – 1.16 0.271 474 4724 all phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.13 1.02 – 1.25 0.0188 464 4518 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.1 1.02 – 1.2 0.0151 695 6822 all phecode
440 Atherosclerosis Circulatory System 1.16 1.11 – 1.21 4.36e-11 2477 19724 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.11 0.964 – 1.27 0.15 231 2291 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.15 1.09 – 1.22 4.91e-07 1516 13532 all phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.27 1.12 – 1.44 0.000204 274 2669 all phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.14 1.07 – 1.22 0.000121 1040 9647 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.18 1.09 – 1.27 1.34e-05 846 8124 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.07 0.977 – 1.18 0.142 515 5115 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.04 0.906 – 1.19 0.599 240 2387 all phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.11 0.935 – 1.31 0.241 154 1536 all phecode
442 Other aneurysm Circulatory System 1.11 1.07 – 1.16 2.71e-07 2779 21466 all phecode
442.1 Aortic aneurysm Circulatory System 1.12 1.06 – 1.17 5.34e-06 2054 16492 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.12 1.05 – 1.19 0.000385 1189 10558 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.13 0.968 – 1.31 0.124 202 2002 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.04 0.888 – 1.21 0.641 179 1765 all phecode
442.4 Arterial dissection Circulatory System 0.938 0.803 – 1.1 0.422 184 1840 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.13 1.02 – 1.26 0.0188 399 3978 all phecode
443 Peripheral vascular disease Circulatory System 1.1 1.06 – 1.14 1.89e-06 3086 24814 all phecode
443.1 Raynaud's syndrome Circulatory System 0.875 0.81 – 0.946 0.000763 742 7390 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.33 1.15 – 1.53 9.23e-05 220 2087 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.1 1.06 – 1.15 4.68e-06 2557 21985 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.16 1.11 – 1.21 5.16e-11 2341 18862 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.11 1.03 – 1.19 0.00505 848 8423 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.995 0.881 – 1.12 0.93 313 3099 all phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 0.995 0.84 – 1.18 0.958 155 1548 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.02 0.925 – 1.13 0.67 460 4559 all phecode
446.4 Wegener's granulomatosis Circulatory System 0.89 0.727 – 1.09 0.26 109 1075 all phecode
446.5 Giant cell arteritis Circulatory System 0.884 0.697 – 1.12 0.306 79 749 all phecode
446.9 Arteritis NOS Circulatory System 1.05 0.928 – 1.19 0.431 289 2876 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.1 1.05 – 1.14 1.27e-05 2647 22765 all phecode
447.1 Stricture of artery Circulatory System 1.19 1.09 – 1.31 0.000215 523 5163 all phecode
447.7 Aortic ectasia Circulatory System 1.06 0.981 – 1.14 0.148 804 7938 all phecode
448 Disease of capillaries Circulatory System 0.854 0.804 – 0.908 3.62e-07 1237 12127 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.08 1.03 – 1.13 0.00159 2104 20985 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.03 0.956 – 1.11 0.414 738 7355 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.06 0.927 – 1.21 0.395 244 2437 all phecode
452 Other venous embolism and thrombosis Circulatory System 1.13 1.09 – 1.16 3.01e-14 4957 29867 all phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1.12 0.985 – 1.27 0.0836 276 2747 all phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1.13 1.09 – 1.18 7.99e-11 3260 26940 all phecode
452.8 Postphlebitic syndrome Circulatory System 1.24 1.05 – 1.46 0.012 154 1529 all phecode
453 Chronic venous hypertension Circulatory System 1.19 1.04 – 1.38 0.0149 220 2168 all phecode
454 Varicose veins Circulatory System 1.06 1.02 – 1.11 0.00335 2827 24555 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1.09 1.04 – 1.14 9.26e-05 2469 21426 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.1 1.04 – 1.16 0.000726 1565 15056 all phecode
455 Hemorrhoids Circulatory System 0.959 0.931 – 0.988 0.00525 5799 29818 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.11 1.07 – 1.16 6.35e-08 3097 24898 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.12 1.07 – 1.17 3e-06 2095 15309 all phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.16 1.03 – 1.31 0.0122 324 3221 all phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.12 1.07 – 1.18 3.87e-06 1973 14689 all phecode
458 Hypotension Circulatory System 1.11 1.08 – 1.14 4.7e-11 5091 32185 all phecode
458.1 Orthostatic hypotension Circulatory System 1.05 0.992 – 1.11 0.0891 1344 12938 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.13 1.06 – 1.2 0.00021 1109 11012 all phecode
458.9 Hypotension NOS Circulatory System 1.11 1.08 – 1.15 1.9e-10 4618 31186 all phecode
459 Other disorders of circulatory system Circulatory System 1.09 1.06 – 1.12 2.02e-11 7825 34792 all phecode
459.1 Hemorrhage NOS Circulatory System 1.01 0.943 – 1.09 0.71 834 8215 all phecode
459.7 Blood vessel replaced Circulatory System 1.14 1.08 – 1.21 7.51e-06 1305 13023 all phecode
459.9 Circulatory disease NEC Circulatory System 1.1 1.07 – 1.13 7.16e-11 6706 33592 all phecode
464 Acute sinusitis Respiratory 0.967 0.937 – 0.998 0.0351 4792 32137 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.969 0.946 – 0.992 0.00846 9601 35915 all phecode
465.2 Acute pharyngitis Respiratory 0.948 0.919 – 0.977 0.000466 5310 32365 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.04 0.937 – 1.15 0.483 443 4428 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.927 0.882 – 0.974 0.00271 1797 17640 all phecode
471 Nasal polyps Respiratory 0.956 0.877 – 1.04 0.312 592 5881 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.963 0.916 – 1.01 0.142 1797 16986 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1 0.963 – 1.04 0.926 2983 25244 all phecode
473.1 Chronic laryngitis Respiratory 1.14 0.893 – 1.46 0.288 68 674 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.998 0.916 – 1.09 0.955 628 6254 all phecode
473.4 Voice disturbance Respiratory 1 0.961 – 1.05 0.857 2336 21975 all phecode
474 Acute and chronic tonsillitis Respiratory 1.04 0.964 – 1.11 0.335 880 7892 all phecode
474.1 Acute tonsillitis Respiratory 0.928 0.827 – 1.04 0.205 335 3181 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.07 0.985 – 1.15 0.113 700 6445 all phecode
475 Chronic sinusitis Respiratory 0.961 0.93 – 0.993 0.0185 4378 27891 all phecode
475.9 Postnasal drip Respiratory 0.888 0.828 – 0.953 0.000959 922 9017 all phecode
476 Allergic rhinitis Respiratory 0.981 0.96 – 1 0.0921 12687 28117 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.07 1 – 1.14 0.0442 1150 11318 all phecode
478 Throat pain Respiratory 1.03 0.932 – 1.14 0.543 426 4195 all phecode
479 Other upper respiratory disease Respiratory 1.01 0.978 – 1.04 0.636 5627 28048 all phecode
480 Pneumonia Respiratory 1.08 1.05 – 1.11 8.74e-08 5947 37034 all phecode
480.1 Bacterial pneumonia Respiratory 1.06 0.992 – 1.12 0.0861 1155 11495 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.08 0.987 – 1.18 0.0956 568 5644 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.02 0.861 – 1.21 0.803 153 1523 all phecode
480.13 MRSA pneumonia Respiratory 1.16 0.959 – 1.39 0.128 117 1165 all phecode
480.2 Viral pneumonia Respiratory 1.16 1 – 1.34 0.048 202 1992 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.02 0.865 – 1.2 0.834 159 1590 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.08 0.908 – 1.29 0.37 135 1312 all phecode
481 Influenza Respiratory 1.04 0.979 – 1.1 0.214 1355 13284 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.02 0.987 – 1.06 0.203 3412 29871 all phecode
495 Asthma Respiratory 1.13 1.11 – 1.16 7.56e-24 8671 33569 all phecode
495.1 Chronic obstructive asthma Respiratory 1.24 1.11 – 1.38 9.16e-05 397 3925 all phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 1.13 0.892 – 1.44 0.305 81 802 all phecode
495.2 Asthma with exacerbation Respiratory 1.08 1.02 – 1.14 0.00537 1629 16033 all phecode
496 Chronic airway obstruction Respiratory 1.2 1.16 – 1.24 3.13e-31 5343 28343 all phecode
496.1 Emphysema Respiratory 1.17 1.12 – 1.23 2.52e-11 2134 19414 all phecode
496.2 Chronic bronchitis Respiratory 1.25 1.2 – 1.29 2.58e-36 4128 26624 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.26 1.21 – 1.31 3.16e-36 3747 25467 all phecode
496.3 Bronchiectasis Respiratory 0.972 0.888 – 1.06 0.54 549 5453 all phecode
497 Bronchitis Respiratory 1.09 1.04 – 1.14 0.000472 1946 18824 all phecode
498 Acute bronchospasm Respiratory 1.3 1.18 – 1.43 1.16e-07 496 4943 all phecode
499 Cystic fibrosis Respiratory 0.908 0.766 – 1.08 0.263 151 1510 all phecode
500 Lung disease due to external agents Respiratory 1.12 1.02 – 1.22 0.0141 557 5551 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1 0.804 – 1.25 0.979 92 920 all phecode
500.2 Pneumoconiosis Respiratory 1.36 1.07 – 1.73 0.0116 78 764 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.09 1 – 1.19 0.0431 634 6225 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.06 0.983 – 1.14 0.13 815 8076 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.2 1.11 – 1.29 1.19e-06 835 8243 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.08 0.985 – 1.17 0.103 595 5878 all phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 1.01 0.896 – 1.14 0.87 311 3084 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.14 1.08 – 1.2 1.55e-06 1638 15749 all phecode
506 Empyema and pneumothorax Respiratory 1.08 1.04 – 1.12 0.000203 2894 25235 all phecode
507 Pleurisy; pleural effusion Respiratory 1.13 1.08 – 1.17 2.45e-09 2916 26208 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.12 1.07 – 1.17 2.57e-07 2382 22588 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.14 1.11 – 1.18 1.16e-14 4032 29477 all phecode
509.1 Respiratory failure Respiratory 1.16 1.11 – 1.22 1.46e-09 1937 18949 all phecode
509.2 Respiratory insufficiency Respiratory 1.13 1.06 – 1.2 0.00021 1174 11679 all phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.1 1.04 – 1.16 0.000299 1689 16489 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.19 1.13 – 1.25 1.53e-11 1741 17249 all phecode
510 Other diseases of lung Respiratory 1.03 1 – 1.06 0.0444 5503 35907 all phecode
510.2 Lung transplant Respiratory 0.924 0.789 – 1.08 0.325 176 1757 all phecode
512 Other symptoms of respiratory system Respiratory 1.07 1.05 – 1.09 5.59e-13 18621 28154 all phecode
512.1 Wheezing Respiratory 1.22 1.16 – 1.3 2.1e-12 1409 13516 all phecode
512.2 Painful respiration Respiratory 1.04 0.99 – 1.08 0.125 2309 21263 all phecode
512.3 Abnormal chest sounds Respiratory 1.03 0.907 – 1.16 0.677 291 2845 all phecode
512.7 Shortness of breath Respiratory 1.13 1.11 – 1.16 4.37e-24 10034 28081 all phecode
512.8 Cough Respiratory 1.06 1.03 – 1.08 1.18e-05 9501 28148 all phecode
512.9 Other dyspnea Respiratory 1.11 1.08 – 1.13 2.85e-18 10804 28104 all phecode
513 Respiratory abnormalities Respiratory 1.12 1.1 – 1.14 1.36e-25 12932 33822 all phecode
513.3 Hypoventilation Respiratory 1.15 1.07 – 1.23 0.000153 880 8646 all phecode
513.31 Apnea Respiratory 1.06 0.959 – 1.17 0.264 462 4607 all phecode
513.32 Orthopnea Respiratory 1.11 0.963 – 1.27 0.154 220 2160 all phecode
513.4 Hyperventilation Respiratory 1.26 1.15 – 1.39 1.04e-06 515 5124 all phecode
513.8 Disorders of diaphragm Respiratory 1.03 0.902 – 1.18 0.652 258 2557 all phecode
514 Abnormal findings examination of lungs Respiratory 1.04 1.01 – 1.08 0.00472 5365 34834 all phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 1.01 0.887 – 1.15 0.856 258 2580 all phecode
514.2 Solitary pulmonary nodule Respiratory 1.03 0.99 – 1.07 0.152 3018 27338 all phecode
516 Abnormal sputum Respiratory 1.1 1.02 – 1.19 0.0135 735 7332 all phecode
516.1 Hemoptysis Respiratory 1.12 1.02 – 1.22 0.012 611 6080 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.08 1.05 – 1.11 1.5e-07 6458 39057 all phecode
519.1 Tracheostomy complications Respiratory 1.25 1.09 – 1.44 0.00173 214 2136 all phecode
519.2 Respiratory complications Respiratory 1.07 0.968 – 1.18 0.186 445 4430 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.03 0.974 – 1.08 0.318 1588 15787 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.08 1.04 – 1.11 4.81e-06 4706 34489 all phecode
520 Disorders of tooth development Digestive 1.1 0.987 – 1.22 0.0866 369 3690 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.28 1.09 – 1.51 0.00323 165 1642 all phecode
520.2 Disturbances in tooth eruption Digestive 1.02 0.884 – 1.17 0.824 218 2172 all phecode
521 Diseases of hard tissues of teeth Digestive 1.15 1.07 – 1.23 7.56e-05 898 8954 all phecode
521.1 Dental caries Digestive 1.17 1.09 – 1.25 2.56e-05 837 8349 all phecode
521.2 Dental abrasion, erosion and attrition Digestive 1.11 0.839 – 1.47 0.46 52 510 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.19 1.09 – 1.31 0.000122 535 5340 all phecode
522.5 Periapical abscess Digestive 1.22 1.1 – 1.34 9.91e-05 459 4583 all phecode
523 Gingival and periodontal diseases Digestive 1.17 1.09 – 1.27 5.66e-05 718 7180 all phecode
523.1 Gingivitis Digestive 1.07 0.901 – 1.27 0.448 142 1418 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.2 1.08 – 1.34 0.000912 364 3636 all phecode
523.31 Acute periodontitis Digestive 1.2 1.07 – 1.35 0.00204 311 3109 all phecode
523.32 Chronic periodontitis Digestive 1.18 0.982 – 1.43 0.0771 122 1204 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.921 0.825 – 1.03 0.144 363 3630 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.887 0.773 – 1.02 0.0904 220 2200 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.18 1.1 – 1.26 7.03e-07 1039 10382 all phecode
525.1 Loss of teeth or edentulism Digestive 1.15 1.03 – 1.29 0.0101 374 3731 all phecode
526 Diseases of the jaws Digestive 0.95 0.912 – 0.989 0.0132 2680 26455 all phecode
526.1 Cysts of the jaws Digestive 0.91 0.798 – 1.04 0.162 247 2470 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.856 0.746 – 0.982 0.0265 241 2383 all phecode
526.4 Temporomandibular joint disorders Digestive 0.916 0.867 – 0.967 0.00161 1504 15025 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.937 0.881 – 0.996 0.036 1187 11858 all phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 0.89 0.823 – 0.962 0.00343 741 7400 all phecode
526.5 Inflammatory conditions of jaw Digestive 1.09 0.966 – 1.24 0.159 287 2864 all phecode
526.8 Exostosis of jaw Digestive 1.27 0.94 – 1.73 0.118 53 521 all phecode
526.9 Jaw disease NOS Digestive 0.984 0.894 – 1.08 0.749 487 4867 all phecode
527 Diseases of the salivary glands Digestive 1.02 0.972 – 1.07 0.406 1781 17771 all phecode
527.1 Hypertrophy of salivary gland Digestive 0.911 0.702 – 1.18 0.484 58 579 all phecode
527.2 Sialoadenitis Digestive 1.04 0.933 – 1.15 0.495 394 3936 all phecode
527.7 Disturbance of salivary secretion Digestive 1.01 0.943 – 1.08 0.772 952 9481 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.14 0.998 – 1.3 0.0537 254 2540 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.974 0.935 – 1.01 0.207 2643 26197 all phecode
528.1 Stomatitis and mucositis Digestive 0.936 0.862 – 1.02 0.11 668 6657 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.03 0.895 – 1.2 0.65 211 2110 all phecode
528.12 Oral aphthae Digestive 0.909 0.788 – 1.05 0.194 215 2137 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.14 0.994 – 1.3 0.0604 235 2338 all phecode
528.4 Cysts of oral soft tissues Digestive 0.801 0.665 – 0.965 0.0193 124 1229 all phecode
528.41 Cyst of the salivary gland Digestive 0.897 0.712 – 1.13 0.359 77 760 all phecode
528.5 Diseases of lips Digestive 0.997 0.904 – 1.1 0.955 462 4602 all phecode
528.6 Leukoplakia of oral mucosa Digestive 0.985 0.823 – 1.18 0.865 137 1370 all phecode
528.7 Sialolithiasis Digestive 1.03 0.873 – 1.22 0.721 163 1623 all phecode
529 Diseases and other conditions of the tongue Digestive 1.04 0.957 – 1.13 0.375 690 6878 all phecode
529.1 Glossitis Digestive 0.974 0.807 – 1.18 0.781 129 1281 all phecode
529.6 Glossodynia Digestive 1.15 0.978 – 1.35 0.0913 168 1652 all phecode
530 Diseases of esophagus Digestive 1.12 1.1 – 1.15 1.61e-30 17081 27931 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.13 1.1 – 1.15 1.22e-30 16572 27931 all phecode
530.11 GERD Digestive 1.13 1.11 – 1.15 2.19e-31 16143 27929 all phecode
530.12 Ulcer of esophagus Digestive 1.11 0.999 – 1.24 0.0512 400 3983 all phecode
530.13 Barrett's esophagus Digestive 1.18 1.09 – 1.27 2.55e-05 762 7584 all phecode
530.14 Reflux esophagitis Digestive 1.09 1.03 – 1.14 0.00104 1900 17495 all phecode
530.15 Eosinophilic esophagitis Digestive 1.11 0.965 – 1.28 0.143 221 2210 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.13 1.04 – 1.22 0.00397 651 6473 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.04 0.974 – 1.12 0.225 911 8971 all phecode
530.5 Disorders of esophageal motility Digestive 1.11 1.02 – 1.22 0.0194 548 5432 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.944 0.781 – 1.14 0.554 129 1265 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.01 0.808 – 1.27 0.921 82 812 all phecode
530.9 Heartburn Digestive 1.1 1.04 – 1.16 0.000591 1519 14928 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.11 1.06 – 1.16 7.59e-06 2073 20617 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.995 0.893 – 1.11 0.927 391 3883 all phecode
531.2 Gastric ulcer Digestive 1.15 1.08 – 1.22 7.21e-06 1201 11970 all phecode
531.3 Duodenal ulcer Digestive 1.04 0.939 – 1.14 0.481 467 4640 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.09 1.01 – 1.18 0.0195 804 8018 all phecode
531.5 Gastrojejunal ulcer Digestive 1.29 1.09 – 1.53 0.00355 150 1500 all phecode
532 Dysphagia Digestive 1.11 1.07 – 1.14 6.79e-11 5585 26852 all phecode
535 Gastritis and duodenitis Digestive 1.06 1.01 – 1.1 0.00759 2799 27335 all phecode
535.1 Acute gastritis Digestive 1.13 1.06 – 1.2 7.97e-05 1178 11750 all phecode
535.2 Atrophic gastritis Digestive 0.997 0.889 – 1.12 0.958 344 3413 all phecode
535.6 Duodenitis Digestive 1.05 0.94 – 1.18 0.371 334 3337 all phecode
535.8 Other specified gastritis Digestive 1.02 0.938 – 1.11 0.642 638 6354 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.996 0.939 – 1.06 0.907 1255 12511 all phecode
536 Disorders of function of stomach Digestive 1.02 0.976 – 1.06 0.451 2911 27685 all phecode
536.3 Gastroparesis Digestive 1.09 1 – 1.18 0.0393 706 6901 all phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.03 0.925 – 1.14 0.626 407 4059 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1 0.959 – 1.05 0.872 2150 21094 all phecode
537 Other disorders of stomach and duodenum Digestive 1.08 1.04 – 1.12 6.55e-05 3183 30048 all phecode
537.1 Lesions of stomach and duodenum Digestive 1.16 0.989 – 1.36 0.0674 173 1725 all phecode
539 Bariatric surgery Digestive 1.85 1.74 – 1.95 1.56e-99 1509 15074 all phecode
540 Appendiceal conditions Digestive 0.981 0.893 – 1.08 0.697 495 4948 all phecode
540.1 Appendicitis Digestive 0.95 0.857 – 1.05 0.33 425 4239 all phecode
540.11 Acute appendicitis Digestive 0.936 0.836 – 1.05 0.252 353 3511 all phecode
550 Abdominal hernia Digestive 1.05 1.02 – 1.07 0.00129 6768 37731 all phecode
550.1 Inguinal hernia Digestive 0.808 0.768 – 0.85 2.08e-16 1744 16488 all phecode
550.2 Diaphragmatic hernia Digestive 1.06 1.02 – 1.1 0.00387 2817 25849 all phecode
550.3 Femoral hernia Digestive 0.775 0.645 – 0.93 0.00622 131 1291 all phecode
550.4 Umbilical hernia Digestive 1.09 1.03 – 1.15 0.00374 1313 13110 all phecode
550.5 Ventral hernia Digestive 1.18 1.13 – 1.23 5.92e-13 2241 22163 all phecode
550.6 Incisional hernia Digestive 1.2 1.13 – 1.27 1.82e-09 1313 13111 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.05 0.999 – 1.11 0.0552 1536 15153 all phecode
555.1 Regional enteritis Digestive 1.09 1.01 – 1.16 0.0183 919 9095 all phecode
555.2 Ulcerative colitis Digestive 0.985 0.919 – 1.06 0.661 937 9315 all phecode
555.21 Ulcerative colitis (chronic) Digestive 0.905 0.825 – 0.993 0.0343 537 5315 all phecode
556 Ulceration of the lower GI tract Digestive 1.07 0.979 – 1.16 0.141 632 6267 all phecode
556.1 Ulceration of intestine Digestive 1.07 0.977 – 1.17 0.145 551 5451 all phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 0.99 0.857 – 1.14 0.893 214 2093 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.22 1.15 – 1.28 7.44e-14 1716 16490 all phecode
557.1 Celiac disease Digestive 0.96 0.866 – 1.06 0.436 421 4026 all phecode
558 Noninfectious gastroenteritis Digestive 1.05 1.01 – 1.09 0.00856 3458 26408 all phecode
559 Ileostomy status Digestive 1.04 0.968 – 1.11 0.306 957 9565 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.06 1.02 – 1.11 0.00189 3004 24851 all phecode
560.1 Paralytic ileus Digestive 1.06 1 – 1.12 0.0331 1627 15714 all phecode
560.2 Impaction of intestine Digestive 1.03 0.922 – 1.15 0.619 387 3779 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.956 0.839 – 1.09 0.5 266 2647 all phecode
560.4 Other intestinal obstruction Digestive 1.07 1.02 – 1.13 0.0103 1651 16170 all phecode
561 Symptoms involving digestive system Digestive 0.997 0.956 – 1.04 0.888 2608 21766 all phecode
562 Diverticulosis and diverticulitis Digestive 1.02 0.992 – 1.05 0.153 6295 23431 all phecode
562.1 Diverticulosis Digestive 1.02 0.992 – 1.05 0.158 6246 23383 all phecode
562.2 Diverticulitis Digestive 1.06 1 – 1.12 0.0377 1611 15162 all phecode
564 Functional digestive disorders Digestive 1.05 1.02 – 1.07 5.2e-05 11411 28676 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.02 0.982 – 1.06 0.318 3457 22266 all phecode
564.9 Personal history of diseases of digestive system Digestive 1.08 1.04 – 1.12 0.000113 3074 25861 all phecode
565 Anal and rectal conditions Digestive 0.972 0.937 – 1.01 0.131 3355 30757 all phecode
565.1 Anal and rectal polyp Digestive 0.989 0.932 – 1.05 0.708 1305 12649 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.14 1.08 – 1.21 5.28e-06 1364 13616 all phecode
568 Other disorders of peritoneum Digestive 1.14 1.08 – 1.2 5.98e-07 1705 17038 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.15 1.08 – 1.22 6.27e-06 1247 12468 all phecode
569 Other disorders of intestine Digestive 1.05 1.02 – 1.08 0.000164 8079 35231 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1 0.89 – 1.12 0.992 326 3260 all phecode
569.2 Gastrointestinal complications Digestive 1.18 1.12 – 1.25 4.43e-09 1395 13933 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.13 1.1 – 1.17 2.32e-14 4610 32562 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.13 1.09 – 1.17 1.69e-13 4342 32234 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.16 1.09 – 1.24 6.99e-06 1018 10095 all phecode
571.6 Primary biliary cirrhosis Digestive 0.992 0.847 – 1.16 0.915 179 1790 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.13 1.05 – 1.21 0.000561 950 9498 all phecode
571.81 Portal hypertension Digestive 1.09 0.996 – 1.19 0.061 573 5730 all phecode
572 Ascites (non malignant) Digestive 1.07 1.02 – 1.12 0.00244 2278 22675 all phecode
573 Other disorders of liver Digestive 1.08 1.05 – 1.11 2.34e-07 5599 33620 all phecode
573.1 Chronic passive congestion of liver Digestive 1.23 1.04 – 1.47 0.0185 136 1359 all phecode
573.2 Liver replaced by transplant Digestive 1.03 0.913 – 1.17 0.619 292 2920 all phecode
573.3 Hepatomegaly Digestive 1.2 1.09 – 1.32 0.000142 470 4700 all phecode
573.4 Acute and subacute necrosis of liver Digestive 0.965 0.857 – 1.09 0.555 316 3149 all phecode
573.5 Jaundice (not of newborn) Digestive 1.04 0.973 – 1.11 0.245 958 9496 all phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.05 1 – 1.09 0.0284 2756 26470 all phecode
573.7 Abnormal results of function study of liver Digestive 1.05 1.01 – 1.09 0.0193 3018 27774 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.04 1.01 – 1.08 0.00848 4679 33866 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.11 1.07 – 1.15 4.63e-08 3177 30809 all phecode
574.1 Cholelithiasis Digestive 1.11 1.07 – 1.16 9.33e-08 2924 28874 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.22 1.09 – 1.36 0.000619 342 3412 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.08 0.985 – 1.18 0.101 553 5501 all phecode
574.2 Calculus of bile duct Digestive 1.03 0.962 – 1.11 0.359 852 8503 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.14 1.06 – 1.22 0.00059 822 8181 all phecode
575 Other biliary tract disease Digestive 1.05 1 – 1.09 0.0457 2266 22555 all phecode
575.1 Cholangitis Digestive 0.971 0.867 – 1.09 0.612 354 3530 all phecode
575.2 Obstruction of bile duct Digestive 1.09 1 – 1.19 0.0428 621 6201 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.946 0.82 – 1.09 0.451 207 2063 all phecode
575.7 Other disorders of gallbladder Digestive 1.03 0.961 – 1.1 0.413 939 9382 all phecode
575.8 Other disorders of biliary tract Digestive 1.06 1 – 1.13 0.0514 1154 11523 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.08 0.944 – 1.23 0.268 260 2600 all phecode
577 Diseases of pancreas Digestive 1.06 1.01 – 1.11 0.0106 2225 22106 all phecode
577.1 Acute pancreatitis Digestive 1.12 1.05 – 1.19 0.000295 1212 12110 all phecode
577.2 Chronic pancreatitis Digestive 1.19 1.08 – 1.31 0.000466 495 4950 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.02 0.934 – 1.12 0.628 570 5601 all phecode
578 Gastrointestinal hemorrhage Digestive 1.03 1 – 1.07 0.0348 4554 37045 all phecode
578.1 Hematemesis Digestive 1.13 1.03 – 1.24 0.0112 485 4842 all phecode
578.2 Blood in stool Digestive 1.05 1.01 – 1.09 0.0208 2743 26554 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.04 0.992 – 1.09 0.111 2210 21750 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.06 1 – 1.12 0.0409 1562 15345 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.1 1.06 – 1.13 1.48e-08 4431 34209 all phecode
579.2 Splenomegaly Digestive 1.22 1.13 – 1.31 8.08e-07 730 7262 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1 0.948 – 1.06 0.925 1410 13877 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.24 1.18 – 1.3 6.22e-17 1881 15516 all phecode
580.1 Glomerulonephritis Genitourinary 1.26 1.14 – 1.4 1.11e-05 401 3992 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.2 1.01 – 1.42 0.0436 146 1440 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.45 1.19 – 1.76 0.000221 114 1128 all phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.01 0.777 – 1.3 0.959 61 600 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.38 1.21 – 1.56 7.23e-07 277 2760 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.24 1.08 – 1.42 0.00257 221 2193 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.24 1.17 – 1.31 7.4e-14 1502 11930 all phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.3 1.22 – 1.4 8e-14 992 7228 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.15 1.06 – 1.24 0.00098 683 6612 all phecode
580.4 Renal sclerosis, NOS Genitourinary 1.24 1.1 – 1.39 0.00039 340 3400 all phecode
585 Renal failure Genitourinary 1.2 1.17 – 1.24 3.25e-41 7470 32340 all phecode
585.1 Acute renal failure Genitourinary 1.2 1.16 – 1.25 4.9e-27 4265 27230 all phecode
585.2 Renal failure NOS Genitourinary 1.24 1.15 – 1.33 1.59e-08 832 8162 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.22 1.18 – 1.25 1.85e-36 5580 29470 all phecode
585.31 Renal dialysis Genitourinary 1.21 1.12 – 1.31 1.05e-06 747 7423 all phecode
585.32 End stage renal disease Genitourinary 1.27 1.18 – 1.35 3.55e-12 1007 9783 all phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.24 1.19 – 1.29 2.32e-26 3209 21312 all phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.24 1.16 – 1.33 4.67e-10 977 9190 all phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.24 1.16 – 1.32 1.2e-11 1227 11191 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.12 1.09 – 1.15 6.62e-17 7628 34189 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.13 1.01 – 1.26 0.0362 349 3480 all phecode
586.11 Small kidney Genitourinary 1.15 0.999 – 1.33 0.0522 210 2093 all phecode
586.12 Vesicoureteral reflux Genitourinary 1.09 0.909 – 1.31 0.352 136 1360 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.04 0.984 – 1.1 0.163 1381 12912 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.11 0.957 – 1.3 0.163 187 1862 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.03 0.98 – 1.08 0.246 1821 17115 all phecode
587 Kidney replaced by transpant Genitourinary 1.13 1.05 – 1.22 0.000773 819 8134 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.22 1.14 – 1.31 8.15e-09 976 9389 all phecode
588.1 Renal osteodystrophy Genitourinary 1.12 0.992 – 1.27 0.0664 290 2900 all phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.21 1.12 – 1.31 1.25e-06 755 7275 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.17 1.09 – 1.25 4.79e-06 1007 9834 all phecode
590 Pyelonephritis Genitourinary 1.11 1.05 – 1.18 0.000114 1461 14350 all phecode
591 Urinary tract infection Genitourinary 1.03 1 – 1.05 0.0201 9873 32513 all phecode
592 Cystitis and urethritis Genitourinary 1.01 0.973 – 1.05 0.557 3038 24207 all phecode
592.1 Cystitis Genitourinary 1.01 0.975 – 1.06 0.471 2880 23279 all phecode
592.11 Acute cystitis Genitourinary 1.01 0.962 – 1.06 0.64 1783 16452 all phecode
592.12 Chronic cystitis Genitourinary 1.04 0.907 – 1.2 0.569 239 2343 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.968 0.875 – 1.07 0.53 431 4310 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.999 0.865 – 1.15 0.987 210 2093 all phecode
593 Hematuria Genitourinary 1.03 0.994 – 1.06 0.118 4859 32063 all phecode
593.1 Gross hematuria Genitourinary 1.02 0.964 – 1.07 0.54 1585 14824 all phecode
593.2 Microscopic hematuria Genitourinary 1.01 0.942 – 1.07 0.852 1049 10301 all phecode
594 Urinary calculus Genitourinary 1.08 1.05 – 1.11 1.09e-08 6707 38209 all phecode
594.1 Calculus of kidney Genitourinary 1.09 1.06 – 1.12 5.81e-09 6273 38051 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.08 0.968 – 1.2 0.171 366 3638 all phecode
594.3 Calculus of ureter Genitourinary 1.08 1.02 – 1.14 0.0109 1361 13561 all phecode
594.8 Renal colic Genitourinary 1.08 0.969 – 1.21 0.157 356 3560 all phecode
595 Hydronephrosis Genitourinary 1.06 1 – 1.11 0.0348 1670 16658 all phecode
596 Other disorders of bladder Genitourinary 1 0.962 – 1.04 0.998 3074 28020 all phecode
596.1 Bladder neck obstruction Genitourinary 0.985 0.886 – 1.1 0.786 400 3942 all phecode
596.5 Functional disorders of bladder Genitourinary 0.998 0.948 – 1.05 0.93 1719 17049 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.984 0.926 – 1.04 0.593 1211 11998 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.941 0.868 – 1.02 0.141 661 6537 all phecode
597.2 Urinary complications NEC Genitourinary 1.01 0.948 – 1.08 0.73 1049 10479 all phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.11 0.949 – 1.29 0.197 189 1873 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.08 0.898 – 1.29 0.42 138 1356 all phecode
598.4 Other cells and casts in urine Genitourinary 1.05 0.864 – 1.27 0.63 122 1192 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.985 – 1.03 0.561 14168 30681 all phecode
599.1 Urinary obstruction Genitourinary 0.883 0.816 – 0.956 0.00221 728 6861 all phecode
599.2 Retention of urine Genitourinary 0.993 0.962 – 1.02 0.655 5034 28305 all phecode
599.3 Dysuria Genitourinary 0.992 0.96 – 1.03 0.647 4397 27849 all phecode
599.4 Urinary incontinence Genitourinary 1.03 1 – 1.07 0.0324 5599 26960 all phecode
599.5 Frequency of urination and polyuria Genitourinary 0.983 0.954 – 1.01 0.27 5498 28723 all phecode
599.6 Oliguria and anuria Genitourinary 1.12 1.03 – 1.22 0.0112 599 5902 all phecode
599.7 Urethral discharge Genitourinary 1.01 0.838 – 1.22 0.892 118 1175 all phecode
599.8 Other symptoms involving urinary system Genitourinary 0.985 0.956 – 1.02 0.337 5446 27963 all phecode
599.9 Other abnormality of urination Genitourinary 0.96 0.923 – 0.998 0.0392 3041 24877 all phecode
600 Hyperplasia of prostate Genitourinary 0.928 0.893 – 0.966 0.000224 4063 11364 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.948 0.889 – 1.01 0.109 1044 9665 all phecode
601.1 Prostatitis Genitourinary 0.826 0.75 – 0.909 9.28e-05 477 4596 all phecode
601.11 Acute prostatitis Genitourinary 0.976 0.804 – 1.18 0.802 124 1200 all phecode
601.12 Chronic prostatitis Genitourinary 0.922 0.743 – 1.15 0.464 95 943 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.07 0.967 – 1.19 0.183 389 3822 all phecode
601.4 Balanoposthitis Genitourinary 0.935 0.775 – 1.13 0.488 127 1224 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.11 0.945 – 1.31 0.204 161 1591 all phecode
602 Other disorders of prostate Genitourinary 0.865 0.774 – 0.968 0.0115 361 3399 all phecode
602.3 Dysplasia of prostate Genitourinary 0.98 0.772 – 1.24 0.865 77 730 all phecode
603 Other disorders of testis Genitourinary 1 0.907 – 1.11 0.974 440 4354 all phecode
603.1 Hydrocele Genitourinary 0.977 0.865 – 1.1 0.706 293 2882 all phecode
603.2 Spermatocele Genitourinary 0.918 0.779 – 1.08 0.309 156 1539 all phecode
604 Disorders of penis Genitourinary 0.938 0.866 – 1.02 0.116 685 6748 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.25 1.05 – 1.48 0.0101 155 1540 all phecode
604.3 Peyronie's disease Genitourinary 0.826 0.716 – 0.953 0.00873 215 2132 all phecode
605 Erectile dysfunction [ED] Genitourinary 0.964 0.928 – 1 0.0561 3776 12700 all phecode
608 Other disorders of male genital organs Genitourinary 0.964 0.914 – 1.02 0.165 1645 13758 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.9 0.814 – 0.995 0.04 424 4196 all phecode
609.1 Infertility, male Genitourinary 0.934 0.83 – 1.05 0.259 302 2992 all phecode
609.11 Azoospermia and oligospermia Genitourinary 1.17 0.946 – 1.45 0.148 95 950 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.816 0.69 – 0.965 0.0172 154 1519 all phecode
610 Benign mammary dysplasias Genitourinary 0.908 0.874 – 0.942 4.14e-07 3683 16548 all phecode
610.1 Cystic mastopathy Genitourinary 0.895 0.848 – 0.944 4.75e-05 1633 14191 all phecode
610.2 Fibroadenosis of breast Genitourinary 0.88 0.675 – 1.15 0.346 60 600 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.892 0.855 – 0.93 7.39e-08 2837 16430 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.894 0.841 – 0.949 0.000272 1269 12191 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.905 0.878 – 0.934 2.01e-10 6067 18690 all phecode
611.1 Abnormal mammogram Genitourinary 0.887 0.857 – 0.917 2.05e-12 4980 16120 all phecode
611.11 Mammographic microcalcification Genitourinary 0.824 0.773 – 0.879 4.44e-09 1122 10394 all phecode
611.3 Lump or mass in breast Genitourinary 0.902 0.869 – 0.936 6.1e-08 3549 18572 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.974 0.912 – 1.04 0.427 1051 10425 all phecode
612.1 Galactorrhea Genitourinary 1.07 0.89 – 1.28 0.491 139 1390 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.996 0.924 – 1.07 0.927 800 7962 all phecode
612.3 Congenital anomalies of breast Genitourinary 0.703 0.549 – 0.9 0.00524 83 810 all phecode
613 Other nonmalignant breast conditions Genitourinary 0.962 0.928 – 0.996 0.0299 3897 22072 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.02 0.94 – 1.12 0.584 593 5874 all phecode
613.5 Mastodynia Genitourinary 0.972 0.923 – 1.02 0.29 1675 16203 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.889 0.827 – 0.955 0.00131 883 8754 all phecode
613.8 Other specified disorders of breast Genitourinary 0.896 0.835 – 0.961 0.00216 932 9248 all phecode
613.9 Breast disorder NOS Genitourinary 0.916 0.867 – 0.969 0.00218 1465 14174 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.988 0.952 – 1.02 0.498 3715 19647 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.01 0.901 – 1.14 0.845 337 3370 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.07 0.97 – 1.18 0.177 478 4773 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.24 0.993 – 1.56 0.0577 94 933 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.931 0.794 – 1.09 0.374 186 1842 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.01 0.882 – 1.16 0.865 246 2460 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.05 0.892 – 1.24 0.545 165 1639 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.976 0.939 – 1.01 0.222 3180 19539 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.03 0.899 – 1.17 0.709 264 2640 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.967 0.928 – 1.01 0.118 2732 18924 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.1 0.916 – 1.32 0.311 132 1311 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.09 0.949 – 1.26 0.217 225 2244 all phecode
615 Endometriosis Genitourinary 0.98 0.929 – 1.03 0.465 1585 14666 all phecode
618 Genital prolapse Genitourinary 0.96 0.916 – 1.01 0.0926 2079 17915 all phecode
618.1 Prolapse of vaginal walls Genitourinary 0.928 0.877 – 0.983 0.0105 1408 13456 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.925 0.844 – 1.01 0.0938 542 5390 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.895 0.793 – 1.01 0.0729 317 3162 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.03 0.936 – 1.14 0.513 441 4394 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.987 0.957 – 1.02 0.388 5728 18687 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.03 0.966 – 1.09 0.396 1233 12082 all phecode
619.2 Disorders of uterus, NEC Genitourinary 0.97 0.888 – 1.06 0.49 591 5897 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.965 0.877 – 1.06 0.47 483 4823 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.983 0.942 – 1.03 0.434 2525 18404 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.01 0.949 – 1.07 0.768 1189 11717 all phecode
620 Dysplasia of female genital organs Genitourinary 1.03 0.931 – 1.15 0.537 395 3950 all phecode
620.1 Dysplasia of cervix Genitourinary 1.04 0.885 – 1.21 0.664 178 1780 all phecode
621 Endometrial hyperplasia Genitourinary 1.12 1.01 – 1.24 0.033 437 4370 all phecode
622 Polyp of female genital organs Genitourinary 0.949 0.898 – 1 0.0666 1449 14264 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.966 0.907 – 1.03 0.278 1132 11189 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.881 0.796 – 0.975 0.014 445 4444 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.01 0.94 – 1.09 0.755 824 8165 all phecode
624 Symptoms involving female genital tract Genitourinary 0.97 0.915 – 1.03 0.296 1348 12518 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.89 0.771 – 1.03 0.112 216 2155 all phecode
624.2 Atrophy of female genital tract Genitourinary 1.11 0.841 – 1.46 0.469 64 615 all phecode
624.9 stress incontinence, female Genitourinary 1.03 0.985 – 1.09 0.18 1935 15408 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.978 0.947 – 1.01 0.154 5653 17303 all phecode
625.1 Dyspareunia Genitourinary 0.944 0.889 – 1 0.0595 1267 12474 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.993 0.962 – 1.02 0.646 5940 15585 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.994 0.959 – 1.03 0.734 4315 14604 all phecode
626.11 Absent or infrequent menstruation Genitourinary 1.03 0.967 – 1.1 0.337 1062 8531 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.02 0.975 – 1.07 0.365 2097 11991 all phecode
626.13 Irregular menstrual cycle Genitourinary 0.991 0.944 – 1.04 0.735 1957 12265 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.989 0.924 – 1.06 0.757 970 8996 all phecode
626.15 Infertility, female, associated with anovulation Genitourinary 1 0.899 – 1.11 0.998 394 3789 all phecode
626.2 Dysmenorrhea Genitourinary 1.04 0.977 – 1.1 0.235 1373 9857 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.961 0.857 – 1.08 0.502 336 3308 all phecode
626.8 Infertility, female Genitourinary 0.951 0.883 – 1.02 0.187 817 6741 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.92 0.889 – 0.953 2.81e-06 4560 14557 all phecode
627.1 Postmenopausal bleeding Genitourinary 0.943 0.885 – 1.01 0.0721 1146 10338 all phecode
627.2 Symptomatic menopause Genitourinary 0.903 0.866 – 0.941 1.23e-06 3017 13763 all phecode
627.21 Symptomatic artificial menopause Genitourinary 0.868 0.729 – 1.03 0.113 152 1514 all phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.758 0.676 – 0.85 2.32e-06 356 3513 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.866 0.809 – 0.927 3.74e-05 997 9484 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.944 0.844 – 1.06 0.312 361 3580 all phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.848 0.752 – 0.956 0.00721 309 3082 all phecode
628 Ovarian cyst Genitourinary 0.994 0.946 – 1.04 0.808 1945 13838 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.99 0.92 – 1.07 0.783 826 8047 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.952 0.838 – 1.08 0.451 273 2715 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.09 0.896 – 1.33 0.384 117 1170 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.908 0.831 – 0.993 0.0336 563 5309 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.91 0.815 – 1.02 0.0955 370 3629 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.884 0.781 – 1 0.052 288 2850 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.959 0.899 – 1.02 0.213 1080 7870 all phecode
636.1 Threatened premature labor Pregnancy Complications 0.925 0.831 – 1.03 0.156 380 3799 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.953 0.841 – 1.08 0.446 288 2868 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.979 0.886 – 1.08 0.682 441 4365 all phecode
636.8 Cervical incompetence Pregnancy Complications 1.03 0.815 – 1.31 0.792 77 770 all phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.15 0.92 – 1.44 0.218 85 850 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.03 0.942 – 1.12 0.549 585 5725 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.02 0.9 – 1.15 0.808 302 3013 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.14 1 – 1.31 0.0463 252 2506 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.18 0.977 – 1.43 0.0845 119 1190 all phecode
644 Anemia during pregnancy Pregnancy Complications 1.09 0.945 – 1.26 0.238 224 2224 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.03 0.959 – 1.11 0.403 855 6531 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.961 0.834 – 1.11 0.589 211 2093 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.04 0.899 – 1.19 0.631 222 2213 all phecode
647.3 Major puerperal infection Pregnancy Complications 1.13 0.875 – 1.46 0.348 65 650 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.983 0.925 – 1.05 0.586 1275 8010 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.04 0.955 – 1.13 0.377 649 5687 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.995 0.912 – 1.09 0.916 587 5463 all phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.01 0.866 – 1.17 0.943 207 2055 all phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 1 0.865 – 1.17 0.961 204 2040 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.931 0.882 – 0.983 0.0094 1624 10064 all phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 0.939 0.862 – 1.02 0.151 616 5533 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.03 0.955 – 1.1 0.486 898 7014 all phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 1.07 0.834 – 1.37 0.592 66 660 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.959 0.892 – 1.03 0.256 887 6802 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.06 0.923 – 1.21 0.427 236 2351 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.14 0.966 – 1.35 0.121 158 1580 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.854 0.732 – 0.997 0.0452 184 1814 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.13 1.1 – 1.17 9.01e-20 6500 38394 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.04 0.977 – 1.1 0.224 1256 11462 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.14 1.06 – 1.22 0.000157 1007 9981 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.17 1.12 – 1.23 2.34e-11 2123 19952 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.18 1.13 – 1.23 7.8e-13 2252 20944 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.17 1.12 – 1.23 2.51e-10 1820 16893 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.22 1.15 – 1.28 6.53e-13 1572 15588 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.12 1.07 – 1.17 9.28e-07 2257 21750 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.11 1.01 – 1.21 0.0267 558 5504 all phecode
686.2 Impetigo Dermatologic 1.05 0.947 – 1.17 0.344 414 4117 all phecode
686.3 Pilonidal cyst Dermatologic 1.17 0.988 – 1.38 0.0692 160 1594 all phecode
686.4 Pyogenic granuloma Dermatologic 0.996 0.845 – 1.18 0.964 158 1570 all phecode
686.5 Pyoderma Dermatologic 1.24 0.943 – 1.62 0.125 63 630 all phecode
687 Symptoms affecting skin Dermatologic 0.969 0.92 – 1.02 0.228 1690 16343 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1 0.973 – 1.03 0.973 7007 34623 all phecode
687.3 Changes in skin texture Dermatologic 1.06 0.957 – 1.17 0.264 415 4121 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.05 1.02 – 1.08 0.000485 6375 34216 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.931 0.909 – 0.953 3.31e-09 9311 37335 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.897 0.87 – 0.925 4.32e-12 5184 31581 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.897 0.87 – 0.925 4.95e-12 5174 31553 all phecode
691 Congenital anomalies of skin Dermatologic 0.975 0.89 – 1.07 0.582 541 5337 all phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 0.97 0.746 – 1.26 0.823 62 613 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.899 0.856 – 0.944 2.15e-05 1861 17936 all phecode
694.1 Vitiligo Dermatologic 1.05 0.882 – 1.26 0.568 137 1347 all phecode
694.2 Other dyschromia Dermatologic 0.889 0.844 – 0.936 8.3e-06 1674 16183 all phecode
694.3 Vascular disorders of skin Dermatologic 1.02 0.807 – 1.28 0.882 82 819 all phecode
695 Erythematous conditions Dermatologic 1.01 0.98 – 1.05 0.428 4120 30247 all phecode
695.1 Toxic erythema Dermatologic 1.13 0.893 – 1.44 0.305 70 688 all phecode
695.2 Bullous dermatoses Dermatologic 0.946 0.75 – 1.19 0.64 85 805 all phecode
695.3 Rosacea Dermatologic 0.899 0.856 – 0.945 3.11e-05 1816 17663 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.06 0.973 – 1.15 0.191 672 6686 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.11 0.972 – 1.27 0.121 247 2437 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.05 0.969 – 1.15 0.223 637 6337 all phecode
695.7 Prurigo and Lichen Dermatologic 0.976 0.896 – 1.06 0.587 605 5986 all phecode
695.8 Other specified erythematous conditions Dermatologic 1.15 1.07 – 1.24 0.000215 812 7980 all phecode
695.81 Erythema nodosum Dermatologic 0.899 0.675 – 1.2 0.468 55 550 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.11 1.03 – 1.2 0.0101 679 6756 all phecode
696 Psoriasis and related disorders Dermatologic 1.02 0.965 – 1.08 0.475 1401 13832 all phecode
696.3 Pityriasis Dermatologic 0.903 0.728 – 1.12 0.356 92 904 all phecode
696.4 Psoriasis Dermatologic 1.04 0.979 – 1.1 0.216 1311 12976 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.04 0.974 – 1.1 0.257 1200 11867 all phecode
696.42 Psoriatic arthropathy Dermatologic 0.967 0.852 – 1.1 0.599 282 2810 all phecode
697 Sarcoidosis Dermatologic 1.04 0.928 – 1.16 0.509 333 3330 all phecode
698 Pruritus and related conditions Dermatologic 0.992 0.948 – 1.04 0.71 2254 21889 all phecode
700 Corns and callosities Dermatologic 1.05 0.991 – 1.11 0.0974 1373 10894 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.992 0.967 – 1.02 0.524 7651 38050 all phecode
701.1 Keratoderma, acquired Dermatologic 1.03 0.942 – 1.12 0.526 567 5524 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.926 0.885 – 0.969 0.00089 2184 21550 all phecode
701.3 Circumscribed scleroderma Dermatologic 0.921 0.842 – 1.01 0.0728 571 5660 all phecode
701.4 Keloid scar Dermatologic 0.925 0.846 – 1.01 0.0833 578 5716 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.08 0.979 – 1.2 0.122 400 3982 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.876 0.852 – 0.901 1.14e-20 6956 29525 all phecode
702.1 Actinic keratosis Dermatologic 0.845 0.817 – 0.875 1.58e-21 4171 26529 all phecode
702.2 Seborrheic keratosis Dermatologic 0.872 0.846 – 0.899 6.9e-19 5480 31552 all phecode
702.4 Degenerative skin disorders Dermatologic 1.12 0.898 – 1.39 0.322 86 832 all phecode
703 Diseases of nail, NOS Dermatologic 1 0.951 – 1.06 0.924 1650 14562 all phecode
703.1 Ingrowing nail Dermatologic 1.04 0.972 – 1.12 0.246 920 8597 all phecode
704 Diseases of hair and hair follicles Dermatologic 0.939 0.904 – 0.975 0.0011 3118 29542 all phecode
704.1 Alopecia Dermatologic 0.901 0.851 – 0.954 0.000316 1408 13871 all phecode
704.11 Alopecia Areata Dermatologic 0.864 0.688 – 1.08 0.207 82 811 all phecode
704.12 Telogen effluvium Dermatologic 0.89 0.679 – 1.17 0.4 63 615 all phecode
704.2 Hirsutism Dermatologic 1.34 1.19 – 1.52 1.92e-06 299 2946 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.948 0.901 – 0.998 0.0399 1752 17189 all phecode
705 Disorders of sweat glands Dermatologic 1.19 1.09 – 1.3 6.91e-05 603 6012 all phecode
705.1 Dyshidrosis Dermatologic 1.06 0.888 – 1.26 0.53 154 1540 all phecode
705.3 Hidradenitis Dermatologic 1.42 1.24 – 1.63 4.44e-07 245 2440 all phecode
705.8 Hyperhidrosis Dermatologic 1.02 0.96 – 1.09 0.486 1112 10986 all phecode
706 Diseases of sebaceous glands Dermatologic 0.916 0.891 – 0.942 1.07e-09 5995 39748 all phecode
706.1 Acne Dermatologic 0.865 0.829 – 0.902 8.84e-12 2594 22570 all phecode
706.2 Sebaceous cyst Dermatologic 0.929 0.893 – 0.967 0.000347 2814 26819 all phecode
706.3 Seborrhea Dermatologic 0.851 0.65 – 1.11 0.239 59 582 all phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.951 0.902 – 1 0.0576 1684 15289 all phecode
707 Chronic ulcer of skin Dermatologic 1.18 1.14 – 1.23 1.63e-16 2871 26816 all phecode
707.1 Decubitus ulcer Dermatologic 1.16 1.08 – 1.25 7.8e-05 825 8119 all phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.27 1.19 – 1.36 1.37e-13 1108 9992 all phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1.16 1.1 – 1.23 1.52e-08 1641 16172 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.992 0.939 – 1.05 0.776 1477 14427 all phecode
709.2 Sicca syndrome Dermatologic 1.01 0.922 – 1.11 0.794 505 4986 all phecode
709.3 Systemic sclerosis Dermatologic 0.868 0.758 – 0.995 0.0419 224 2209 all phecode
709.5 Dermatomyositis Dermatologic 1.14 0.927 – 1.41 0.213 92 892 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.07 0.85 – 1.35 0.562 90 892 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.01 0.946 – 1.09 0.688 917 9089 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.2 1.13 – 1.27 4.84e-09 1254 12103 all phecode
710.1 Osteomyelitis Musculoskeletal 1.2 1.13 – 1.28 3.65e-09 1203 11636 all phecode
710.11 Acute osteomyelitis Musculoskeletal 1.37 1.25 – 1.49 4.9e-12 590 5708 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.23 1.12 – 1.35 1.18e-05 531 5163 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.21 1.13 – 1.28 4.28e-09 1153 11149 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.05 0.947 – 1.17 0.343 410 4099 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.17 1.04 – 1.33 0.0121 290 2900 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.3 1.1 – 1.53 0.00186 178 1776 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.16 1.03 – 1.31 0.0138 314 3028 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.23 1.05 – 1.43 0.00954 194 1824 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.11 1.06 – 1.17 7.01e-06 2086 18159 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.15 1.09 – 1.22 1.16e-07 1670 15087 all phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.02 0.814 – 1.29 0.839 77 767 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.13 1.06 – 1.2 9.22e-05 1209 11967 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.23 1.08 – 1.4 0.00233 262 2611 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.18 1.02 – 1.36 0.0253 219 2182 all phecode
716 Other arthropathies Musculoskeletal 1.12 1.1 – 1.15 7.57e-26 13482 31305 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.05 0.903 – 1.23 0.507 192 1920 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.955 0.793 – 1.15 0.626 131 1293 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.12 1.1 – 1.15 7.62e-26 13410 31294 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.941 0.824 – 1.08 0.373 261 2565 all phecode
720 Spinal stenosis Musculoskeletal 1.09 1.06 – 1.13 4.08e-07 3958 28539 all phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1.1 1.06 – 1.15 1.54e-06 2872 23656 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1.05 1.02 – 1.08 0.00207 5509 32391 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.04 1.01 – 1.07 0.0158 5153 31896 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.07 0.999 – 1.16 0.0528 867 8629 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.21 1.06 – 1.38 0.0047 262 2600 all phecode
722 Intervertebral disc disorders Musculoskeletal 1.08 1.05 – 1.11 4.53e-08 6284 34317 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.07 1.03 – 1.1 0.000468 3591 31411 all phecode
722.3 Schmorl's nodes Musculoskeletal 1.19 0.973 – 1.45 0.0917 126 1248 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.07 1.03 – 1.11 9.59e-05 3957 30744 all phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.06 0.965 – 1.17 0.223 515 5140 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.07 0.965 – 1.19 0.193 397 3968 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.03 0.982 – 1.08 0.225 1932 19288 all phecode
723 Other disorders of cervical region Musculoskeletal 1 0.935 – 1.07 0.971 952 9495 all phecode
723.1 Torticollis Musculoskeletal 1 0.878 – 1.14 0.988 254 2522 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.06 1.03 – 1.1 0.000612 4130 31954 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.07 1.03 – 1.12 0.00149 2307 21902 all phecode
724.2 Disorders of coccyx Musculoskeletal 1.05 0.95 – 1.17 0.319 426 4215 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.08 1.01 – 1.16 0.0263 931 9295 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.06 0.999 – 1.12 0.0527 1412 14087 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.979 0.956 – 1 0.0828 9917 30176 all phecode
726.1 Enthesopathy Musculoskeletal 0.975 0.95 – 1 0.0577 7507 30106 all phecode
726.2 Synoviopathy Musculoskeletal 0.98 0.917 – 1.05 0.558 1015 9987 all phecode
726.3 Bursitis Musculoskeletal 0.954 0.908 – 1 0.0663 1829 16722 all phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 1.01 0.947 – 1.07 0.848 1193 11485 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.989 0.963 – 1.02 0.402 7425 30105 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.994 0.956 – 1.03 0.747 3092 24998 all phecode
727.2 Bursitis disorders Musculoskeletal 0.986 0.888 – 1.09 0.788 419 4112 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.943 0.891 – 0.998 0.0423 1400 13621 all phecode
727.5 Rupture of synovium Musculoskeletal 1.09 0.988 – 1.2 0.0851 480 4672 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.983 0.942 – 1.03 0.442 2461 21948 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.997 0.914 – 1.09 0.941 591 5893 all phecode
727.8 Plica syndrome Musculoskeletal 0.931 0.779 – 1.11 0.437 130 1264 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.02 0.989 – 1.06 0.191 4546 29473 all phecode
728.1 Muscular calcification and ossification Musculoskeletal 0.924 0.743 – 1.15 0.474 85 843 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.938 0.831 – 1.06 0.302 297 2949 all phecode
728.7 Fasciitis Musculoskeletal 0.971 0.933 – 1.01 0.157 2814 23463 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.811 0.731 – 0.899 7.16e-05 419 4138 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.12 1.08 – 1.16 2.94e-09 3642 27471 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.01 0.786 – 1.29 0.945 74 726 all phecode
729.3 Panniculitis Musculoskeletal 1.36 1.12 – 1.65 0.00168 119 1174 all phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 0.985 0.765 – 1.27 0.905 67 664 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.23 1.07 – 1.42 0.00421 210 2091 all phecode
732 Osteochondropathies Musculoskeletal 1.12 1 – 1.25 0.0418 361 3604 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.2 1.04 – 1.4 0.0154 198 1969 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.04 0.834 – 1.3 0.713 90 882 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.912 0.882 – 0.942 4.97e-08 4543 26941 all phecode
733.2 Cyst of bone Musculoskeletal 0.915 0.786 – 1.07 0.251 190 1900 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.981 0.894 – 1.08 0.689 518 5160 all phecode
733.6 Costochondritis Musculoskeletal 0.912 0.817 – 1.02 0.102 357 3562 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.07 0.998 – 1.16 0.0551 822 8205 all phecode
733.9 Chondromalacia Musculoskeletal 0.961 0.78 – 1.19 0.713 96 960 all phecode
735 Acquired foot deformities Musculoskeletal 0.958 0.923 – 0.993 0.0201 3417 29622 all phecode
735.1 Flat foot Musculoskeletal 0.971 0.892 – 1.06 0.489 620 6092 all phecode
735.2 Acquired toe deformities Musculoskeletal 0.969 0.913 – 1.03 0.294 1323 11983 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.993 0.921 – 1.07 0.85 825 7494 all phecode
735.23 Hallux rigidus Musculoskeletal 0.945 0.851 – 1.05 0.295 405 4005 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.912 0.863 – 0.963 0.00094 1470 14295 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.972 0.934 – 1.01 0.173 2763 26555 all phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.864 0.703 – 1.06 0.165 104 1033 all phecode
736.2 Acquired deformities of finger Musculoskeletal 0.866 0.748 – 1 0.0554 215 2142 all phecode
736.3 Acquired deformities of hip Musculoskeletal 1.01 0.771 – 1.33 0.937 60 590 all phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.98 0.873 – 1.1 0.729 325 3247 all phecode
736.5 Acquired deformities of knee Musculoskeletal 0.951 0.835 – 1.08 0.447 246 2460 all phecode
736.6 Unequal leg length (acquired) Musculoskeletal 1.01 0.899 – 1.12 0.926 339 3365 all phecode
737 Curvature of spine Musculoskeletal 0.947 0.897 – 0.999 0.0455 1566 15543 all phecode
737.1 Kyphosis (acquired) Musculoskeletal 1.01 0.918 – 1.12 0.817 479 4748 all phecode
737.2 Lordosis (acquired) Musculoskeletal 1.32 1.02 – 1.7 0.0335 70 700 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.929 0.874 – 0.988 0.0189 1203 11982 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.01 0.97 – 1.06 0.584 2443 24187 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.1 1.03 – 1.18 0.00367 1057 10542 all phecode
739 Contracture of joint Musculoskeletal 0.994 0.913 – 1.08 0.896 621 6207 all phecode
740 Osteoarthrosis Musculoskeletal 1.14 1.11 – 1.16 5.64e-34 16169 30268 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.1 1.07 – 1.13 6.29e-12 7005 27422 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.09 1.06 – 1.12 1.75e-08 6176 26155 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.18 1.09 – 1.28 6.72e-05 713 7116 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.05 0.989 – 1.1 0.119 1609 12092 all phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 1.12 1 – 1.25 0.0498 373 3586 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.14 1.12 – 1.17 4e-35 15497 30141 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.01 0.983 – 1.03 0.558 8555 35884 all phecode
741.1 Ankylosis of joint Musculoskeletal 0.917 0.801 – 1.05 0.211 245 2445 all phecode
741.2 Stiffness of joint Musculoskeletal 0.92 0.867 – 0.977 0.00649 1268 12594 all phecode
741.3 Difficulty in walking Musculoskeletal 1.07 1.02 – 1.12 0.00194 2558 23116 all phecode
741.4 Joint effusions Musculoskeletal 0.991 0.95 – 1.03 0.683 2493 24199 all phecode
741.5 Hemarthrosis Musculoskeletal 1.08 0.87 – 1.35 0.476 94 937 all phecode
741.6 Villonodular synovitis Musculoskeletal 0.89 0.685 – 1.16 0.385 68 666 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.01 0.979 – 1.04 0.497 4404 33771 all phecode
742.1 Loose body in joint Musculoskeletal 1.24 1.05 – 1.46 0.0115 156 1554 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.919 0.812 – 1.04 0.18 280 2792 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.04 0.908 – 1.19 0.578 245 2450 all phecode
742.9 Other derangement of joint Musculoskeletal 1.01 0.979 – 1.05 0.46 4107 32972 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.929 0.906 – 0.952 3.67e-09 9223 36921 all phecode
743.1 Osteoporosis Musculoskeletal 0.904 0.871 – 0.939 1.95e-07 3712 19477 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.901 0.868 – 0.937 1.04e-07 3657 19276 all phecode
743.12 Senile osteoporosis Musculoskeletal 0.798 0.735 – 0.867 9.82e-08 703 5804 all phecode
743.13 Other specified osteoporosis Musculoskeletal 0.911 0.808 – 1.03 0.129 321 3141 all phecode
743.2 Pathologic fracture Musculoskeletal 0.945 0.886 – 1.01 0.082 1112 10563 all phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 0.949 0.86 – 1.05 0.294 475 4629 all phecode
743.22 Pathologic fracture of femur Musculoskeletal 0.989 0.828 – 1.18 0.904 143 1391 all phecode
743.4 Stress fracture Musculoskeletal 0.947 0.853 – 1.05 0.313 407 4046 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.918 0.894 – 0.944 1.06e-09 6970 35237 all phecode
745 Pain in joint Musculoskeletal 0.991 0.972 – 1.01 0.345 19848 26918 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.02 0.98 – 1.07 0.29 2236 22256 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.06 1.01 – 1.12 0.0191 1767 17598 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.963 0.887 – 1.05 0.367 650 6497 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.06 0.984 – 1.15 0.12 751 7480 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.14 1.03 – 1.27 0.0115 410 4090 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.921 0.839 – 1.01 0.0846 501 5010 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.989 0.814 – 1.2 0.908 111 1110 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.921 0.842 – 1.01 0.0685 555 5549 all phecode
749.1 Cleft palate Congenital Anomalies 0.914 0.74 – 1.13 0.403 97 970 all phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 1.03 0.839 – 1.26 0.793 105 1041 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.933 0.87 – 1 0.0544 893 8919 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.932 0.835 – 1.04 0.204 366 3655 all phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.896 0.741 – 1.08 0.261 119 1185 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.906 0.733 – 1.12 0.358 99 982 all phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 0.88 0.734 – 1.06 0.168 134 1332 all phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 1.12 0.855 – 1.47 0.404 60 593 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.919 0.839 – 1.01 0.0713 531 5300 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.857 0.762 – 0.964 0.0102 313 3129 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.03 0.892 – 1.18 0.71 222 2214 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.979 0.935 – 1.03 0.383 2008 19975 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.982 0.9 – 1.07 0.682 574 5740 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.01 0.904 – 1.12 0.906 384 3840 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.939 0.797 – 1.11 0.449 153 1527 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.976 0.922 – 1.03 0.403 1379 13704 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.943 0.882 – 1.01 0.0911 976 9685 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.985 0.874 – 1.11 0.801 294 2927 all phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.1 0.943 – 1.28 0.229 182 1809 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.11 1.04 – 1.18 0.00151 1133 11313 all phecode
752.1 Neural tube defects Congenital Anomalies 1.14 1.06 – 1.22 0.000227 923 9209 all phecode
752.11 Spina bifida Congenital Anomalies 1.14 0.975 – 1.32 0.103 176 1760 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1 0.876 – 1.15 0.979 232 2320 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.05 0.905 – 1.22 0.517 207 2051 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.934 0.711 – 1.23 0.624 58 580 all phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 1.01 0.761 – 1.34 0.943 56 546 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.09 1.03 – 1.16 0.00461 1216 12116 all phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 1.07 0.89 – 1.27 0.491 135 1333 all phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 1.07 0.978 – 1.17 0.141 558 5570 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1 0.926 – 1.08 0.998 747 7458 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.995 0.894 – 1.11 0.929 368 3663 all phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 1.02 0.797 – 1.29 0.899 74 740 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.99 0.879 – 1.12 0.871 321 3205 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.05 0.896 – 1.23 0.552 185 1847 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.963 0.909 – 1.02 0.196 1358 13579 all phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.879 0.686 – 1.13 0.309 68 680 all phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 0.942 0.74 – 1.2 0.628 71 694 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.903 0.806 – 1.01 0.0818 335 3346 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.99 0.926 – 1.06 0.76 1003 10014 all phecode
757 Congenital anomalies of the integument Congenital Anomalies 0.87 0.784 – 0.966 0.00932 401 4001 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.905 0.776 – 1.05 0.201 185 1845 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.878 0.732 – 1.05 0.16 135 1349 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.01 0.924 – 1.1 0.827 557 5566 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.901 0.702 – 1.16 0.412 71 710 all phecode
760 Back pain Symptoms 1.06 1.04 – 1.08 9.44e-10 16037 30719 all phecode
761 Cervicalgia Symptoms 1 0.974 – 1.03 0.947 6528 39755 all phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 1.05 1.01 – 1.08 0.0146 3657 32599 all phecode
764 Sciatica Symptoms 1.08 1.04 – 1.12 3.65e-05 3542 32015 all phecode
765 Cervical radiculitis Symptoms 0.987 0.939 – 1.04 0.623 1799 17851 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.06 1.02 – 1.09 0.000468 5124 37132 all phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 0.937 0.772 – 1.14 0.512 117 1168 all phecode
769 Nonallopathic lesions NEC Symptoms 0.97 0.911 – 1.03 0.353 1131 11220 all phecode
770 Myalgia and myositis unspecified Symptoms 1.05 1.02 – 1.08 0.00159 5533 34303 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.05 1.02 – 1.09 0.000833 4799 35575 all phecode
771.1 Swelling of limb Symptoms 1.13 1.1 – 1.17 4.7e-17 5743 35539 all phecode
771.2 Cramp of limb Symptoms 1.09 1.02 – 1.16 0.0123 1079 10568 all phecode
772 Symptoms of the muscles Symptoms 0.915 0.873 – 0.959 0.00022 2042 20221 all phecode
772.1 Muscular wasting and disuse atrophy Symptoms 0.995 0.897 – 1.1 0.917 422 4199 all phecode
772.2 Spasm of muscle Symptoms 1.01 0.971 – 1.06 0.527 2299 22726 all phecode
772.3 Muscle weakness Symptoms 1.04 1 – 1.08 0.0367 2949 28064 all phecode
772.4 Rhabdomyolysis Symptoms 1.13 0.953 – 1.34 0.161 159 1572 all phecode
772.6 Facial weakness Symptoms 0.976 0.885 – 1.08 0.623 478 4742 all phecode
780 Hypothermia/Chills Symptoms 0.973 0.881 – 1.07 0.581 453 4514 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.01 0.974 – 1.06 0.495 2822 26225 all phecode
781.1 Loss of height Symptoms 1.01 0.836 – 1.23 0.899 130 1269 all phecode
781.2 Abnormal posture Symptoms 0.931 0.714 – 1.21 0.598 57 567 all phecode
782.3 Edema Symptoms 1.17 1.14 – 1.21 4.15e-27 5874 36788 all phecode
782.6 Pallor and flushing Symptoms 0.927 0.865 – 0.994 0.0337 927 9252 all phecode
783 Fever of unknown origin Symptoms 1.06 1.03 – 1.09 5.59e-05 5733 40720 all phecode
783.1 Postprocedural fever Symptoms 1.09 0.965 – 1.23 0.165 300 2992 all phecode
785 Abdominal pain Symptoms 1.04 1.02 – 1.06 1.95e-05 16458 30297 all phecode
788 Syncope and collapse Symptoms 1.02 0.988 – 1.06 0.213 3851 35832 all phecode
789 Nausea and vomiting Symptoms 1.05 1.03 – 1.07 1.6e-05 10568 36098 all phecode
789.1 Persistent vomiting Symptoms 1.15 1.07 – 1.24 0.000226 798 7924 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.08 1.03 – 1.13 0.000692 2363 22690 all phecode
790.1 Elevated sedimentation rate Symptoms 1.09 0.95 – 1.25 0.221 236 2322 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.07 1.04 – 1.1 2.2e-07 7539 37788 all phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.26 1.12 – 1.42 0.000124 309 3075 all phecode
790.9 Abnormal arterial blood gases Symptoms 1.21 1.02 – 1.44 0.028 155 1521 all phecode
791 Gangrene Symptoms 1.22 1.08 – 1.37 0.00113 313 3115 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 0.967 0.928 – 1.01 0.115 2820 14872 all phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 0.973 0.913 – 1.04 0.409 1100 9861 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.961 0.876 – 1.05 0.401 515 5133 all phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 0.989 0.945 – 1.03 0.631 2182 20242 all phecode
795.8 Abnormal tumor markers Symptoms 0.917 0.871 – 0.965 0.000901 1745 15551 all phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 1.16 0.889 – 1.51 0.274 61 605 all phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 0.944 0.814 – 1.1 0.447 201 2000 all phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.867 0.826 – 0.911 1.68e-08 2125 9930 all phecode
797 Shock Symptoms 1.07 0.98 – 1.17 0.132 605 6050 all phecode
797.1 Cardiogenic shock Symptoms 1.17 1.03 – 1.34 0.0192 242 2420 all phecode
798 Malaise and fatigue Symptoms 1.01 0.984 – 1.03 0.598 11539 35196 all phecode
798.1 Chronic fatigue syndrome Symptoms 0.998 0.949 – 1.05 0.935 1823 17795 all phecode
800 Fracture of lower limb Injuries & Poisonings 0.965 0.923 – 1.01 0.106 2344 22951 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.983 0.895 – 1.08 0.72 512 4961 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.955 0.88 – 1.04 0.27 670 6582 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.981 0.915 – 1.05 0.586 898 8966 all phecode
800.4 Fracture of patella Injuries & Poisonings 0.936 0.837 – 1.05 0.25 346 3456 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1 0.962 – 1.05 0.844 2358 22645 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.03 0.965 – 1.09 0.394 1120 11178 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.965 0.866 – 1.08 0.525 380 3765 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.936 0.894 – 0.981 0.00547 2051 20360 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.06 0.983 – 1.15 0.126 734 7322 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.898 0.844 – 0.956 0.00081 1112 11075 all phecode
803.21 Colles' fracture Injuries & Poisonings 0.862 0.764 – 0.973 0.0165 291 2904 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.862 0.786 – 0.946 0.00165 514 5140 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.906 0.861 – 0.955 0.000199 1628 16042 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.01 0.95 – 1.07 0.822 1336 13242 all phecode
807 Fracture of ribs Injuries & Poisonings 0.98 0.906 – 1.06 0.624 683 6815 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.957 0.921 – 0.995 0.0273 2941 28633 all phecode
816 Cerebral laceration and contusion Injuries & Poisonings 1.22 0.92 – 1.62 0.168 54 531 all phecode
817 Concussion Injuries & Poisonings 0.999 0.936 – 1.07 0.978 1018 10149 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.851 0.757 – 0.958 0.00739 311 3104 all phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.87 0.701 – 1.08 0.207 90 895 all phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 0.975 0.788 – 1.21 0.818 97 970 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.962 0.921 – 1.01 0.0856 2287 22671 all phecode
830 Dislocation Injuries & Poisonings 0.957 0.925 – 0.99 0.0109 3862 34720 all phecode
835 Internal derangement of knee Injuries & Poisonings 0.992 0.949 – 1.04 0.719 2231 21628 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.1 0.995 – 1.21 0.0633 496 4954 all phecode
840 Sprains and strains Injuries & Poisonings 0.97 0.946 – 0.995 0.0178 7838 37998 all phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.981 0.896 – 1.08 0.687 537 5356 all phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 1.03 0.978 – 1.09 0.257 1640 16263 all phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.921 0.886 – 0.959 5.03e-05 2875 24879 all phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.972 0.922 – 1.03 0.299 1583 15592 all phecode
842 Other sprains and strains Injuries & Poisonings 0.954 0.903 – 1.01 0.1 1407 13924 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.09 1.04 – 1.14 0.000376 2072 20649 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.14 1.1 – 1.19 1.36e-11 2982 27545 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.08 0.979 – 1.19 0.125 460 4600 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.14 1.09 – 1.2 3.55e-08 1985 19675 all phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.08 0.952 – 1.24 0.224 264 2640 all phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.06 0.94 – 1.2 0.327 293 2929 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.09 1.03 – 1.16 0.004 1310 13087 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.07 1.03 – 1.12 0.00183 2213 21944 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.08 1.03 – 1.13 0.000979 2110 21070 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1.07 0.907 – 1.25 0.441 166 1660 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.03 0.998 – 1.07 0.0629 4117 36734 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.995 0.856 – 1.16 0.943 204 2026 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.901 0.758 – 1.07 0.236 144 1437 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.885 0.835 – 0.937 3.13e-05 1346 13301 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.945 0.817 – 1.09 0.447 207 2057 all phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 0.943 0.829 – 1.07 0.369 275 2724 all phecode
870.6 Open wound of neck Injuries & Poisonings 0.999 0.864 – 1.16 0.993 214 2128 all phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.16 0.974 – 1.37 0.0979 144 1440 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.04 1 – 1.08 0.0277 3530 32903 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.993 0.908 – 1.09 0.873 572 5701 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.935 0.874 – 1 0.0507 984 9772 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.26 1.15 – 1.39 1.98e-06 490 4843 all phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.12 0.994 – 1.27 0.0632 295 2921 all phecode
872 Traumatic amputation Injuries & Poisonings 1.17 1.07 – 1.28 0.000743 551 5477 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.31 1.11 – 1.53 0.00101 170 1697 all phecode
875 Non-healing surgical wound Injuries & Poisonings 1.2 1.1 – 1.31 4.33e-05 572 5720 all phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.29 1.19 – 1.39 5.87e-11 802 8003 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.02 0.95 – 1.08 0.656 1010 10096 all phecode
910 Superficial injury, infected Injuries & Poisonings 0.936 0.774 – 1.13 0.499 119 1161 all phecode
911 Blister Injuries & Poisonings 1.15 1.02 – 1.29 0.0267 302 2996 all phecode
912 Insect bite Injuries & Poisonings 0.974 0.885 – 1.07 0.584 492 4886 all phecode
913 Toxic effect of venom Injuries & Poisonings 0.774 0.688 – 0.871 1.95e-05 337 3326 all phecode
916 Contusion Injuries & Poisonings 1.03 0.992 – 1.06 0.136 4296 38033 all phecode
930 Allergic reaction to food Injuries & Poisonings 1.01 0.94 – 1.1 0.714 763 7596 all phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.929 0.858 – 1.01 0.0673 714 7072 all phecode
938 Dermatitis due to solar radiation Dermatologic 0.882 0.856 – 0.909 3.89e-16 5567 29098 all phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 1.01 0.873 – 1.16 0.921 217 2164 all phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.874 0.847 – 0.901 1.2e-17 5307 28656 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.968 0.942 – 0.995 0.0193 6704 32389 all phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 1 0.795 – 1.26 0.998 91 870 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.13 0.97 – 1.31 0.118 188 1880 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.04 0.907 – 1.18 0.606 269 2688 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.975 0.887 – 1.07 0.603 500 4940 all phecode
947 Urticaria Dermatologic 0.978 0.919 – 1.04 0.479 1177 11454 all phecode
949 Allergies, other Injuries & Poisonings 1.01 0.982 – 1.04 0.546 7251 32350 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.04 0.947 – 1.15 0.403 494 4940 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.887 0.743 – 1.06 0.188 136 1352 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.09 1.02 – 1.15 0.00738 1217 12158 all phecode
958.1 Postoperative shock Injuries & Poisonings 1 0.85 – 1.18 0.99 169 1688 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.957 0.785 – 1.17 0.667 114 1140 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.14 1.09 – 1.19 1.95e-09 2479 22087 all phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 1.07 0.952 – 1.2 0.257 342 3403 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.16 1.1 – 1.22 2.21e-08 1636 16005 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.12 1.02 – 1.23 0.0147 528 5234 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.12 1.05 – 1.19 0.000936 1065 10347 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.06 0.986 – 1.15 0.111 803 7976 all phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.04 0.932 – 1.16 0.498 379 3782 all phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 1.18 0.91 – 1.54 0.21 62 612 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.07 0.97 – 1.18 0.179 478 4773 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1 0.961 – 1.05 0.892 2533 24531 all phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.01 0.968 – 1.05 0.625 2469 24057 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.12 1.04 – 1.22 0.00318 743 7337 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.13 1.04 – 1.22 0.00243 712 7027 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.07 0.997 – 1.15 0.0609 864 8601 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.15 1.09 – 1.21 1.19e-06 1469 14402 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.904 0.75 – 1.09 0.291 119 1182 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.967 0.788 – 1.19 0.745 103 1006 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.995 0.937 – 1.06 0.872 1254 12464 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.13 1 – 1.28 0.0502 281 2797 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.08 0.838 – 1.4 0.539 67 643 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.19 1.05 – 1.34 0.00673 288 2858 all phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 1.18 0.929 – 1.49 0.178 80 776 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.24 1.02 – 1.51 0.0323 104 1034 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.17 0.964 – 1.42 0.112 113 1130 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.07 0.846 – 1.35 0.573 81 810 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.12 0.868 – 1.44 0.388 71 703 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.11 1.05 – 1.16 9.03e-05 1763 16599 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.04 1.01 – 1.08 0.0218 3448 30885 all phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 1.02 0.967 – 1.08 0.43 1391 13877 all phecode
985 Toxic effect of other metals Injuries & Poisonings 1.18 0.897 – 1.56 0.235 57 564 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.01 0.842 – 1.21 0.919 129 1275 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.02 0.985 – 1.05 0.283 3927 31223 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.14 1.09 – 1.19 1.97e-08 2192 21710 all phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.18 1.04 – 1.34 0.00945 291 2910 all phecode
994.2 Sepsis Injuries & Poisonings 1.14 1.09 – 1.19 3.24e-08 2086 20666 all phecode
994.21 Septic shock Injuries & Poisonings 1.17 1.08 – 1.28 0.000208 627 6260 all phecode
008 Intestinal infection Infectious Diseases 1.02 0.947 – 1.11 0.562 745 6950 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.18 1.05 – 1.33 0.00538 321 2987 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.2 1.05 – 1.37 0.00664 251 2331 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.06 0.904 – 1.25 0.457 168 1792 exclusion phecode
010 Tuberculosis Infectious Diseases 1.1 0.853 – 1.43 0.454 61 539 exclusion phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.915 0.616 – 1.36 0.659 27 197 exclusion phecode
038 Septicemia Infectious Diseases 1.26 1.15 – 1.38 4.49e-07 551 5136 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.15 0.955 – 1.39 0.138 115 1172 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.44 1.07 – 1.94 0.0147 50 455 exclusion phecode
038.3 Bacteremia Infectious Diseases 1.21 1.06 – 1.37 0.00399 266 2396 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.14 1.08 – 1.21 9.52e-06 1319 9006 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.37 1.23 – 1.53 2.78e-08 349 3617 exclusion phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.4 1.2 – 1.63 2.08e-05 181 1916 exclusion phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.33 1.13 – 1.57 0.00061 157 1700 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.24 1.12 – 1.38 7.43e-05 381 3462 exclusion phecode
041.21 Rheumatic fever / chorea Infectious Diseases 1.12 0.829 – 1.52 0.456 50 554 exclusion phecode
041.4 E. coli Infectious Diseases 1.24 1.08 – 1.41 0.00173 260 2614 exclusion phecode
041.8 H. pylori Infectious Diseases 0.925 0.701 – 1.22 0.58 58 595 exclusion phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.42 1.14 – 1.78 0.00208 96 849 exclusion phecode
053 Herpes zoster Infectious Diseases 0.925 0.828 – 1.03 0.168 369 3324 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.97 0.73 – 1.29 0.836 50 459 exclusion phecode
054 Herpes simplex Infectious Diseases 0.939 0.846 – 1.04 0.232 422 3794 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.15 0.98 – 1.35 0.087 193 1614 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.67 0.933 – 3 0.0843 11 160 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.903 0.675 – 1.21 0.49 52 441 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.27 1.05 – 1.54 0.0154 129 966 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.05 0.77 – 1.44 0.753 53 395 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.2 1.05 – 1.38 0.00805 245 2187 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.48 1.12 – 1.96 0.00661 59 289 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.48 1.09 – 2.01 0.0115 50 218 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.913 0.851 – 0.98 0.0118 911 7141 exclusion phecode
079 Viral infection Infectious Diseases 0.984 0.933 – 1.04 0.558 1707 8160 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.907 0.846 – 0.971 0.00544 975 7161 exclusion phecode
079.2 Infectious mononucleosis Infectious Diseases 0.856 0.695 – 1.05 0.142 106 885 exclusion phecode
079.9 Viremia, NOS Infectious Diseases 1.2 1.04 – 1.39 0.0122 214 2028 exclusion phecode
080 Postoperative infection Infectious Diseases 1.21 1.1 – 1.32 3.54e-05 540 5845 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.25 1.13 – 1.4 3.84e-05 389 3473 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.02 0.9 – 1.15 0.762 277 2444 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.957 0.881 – 1.04 0.296 644 6718 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.971 0.889 – 1.06 0.523 555 6022 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.936 0.835 – 1.05 0.256 340 3534 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.03 0.858 – 1.24 0.751 129 1645 exclusion phecode
110.13 Dermatophytosis of the body Infectious Diseases 0.919 0.771 – 1.09 0.343 131 1711 exclusion phecode
110.2 Dermatomycoses Infectious Diseases 0.97 0.791 – 1.19 0.774 103 952 exclusion phecode
112 Candidiasis Infectious Diseases 1.14 1.06 – 1.22 0.000402 876 7564 exclusion phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.09 0.832 – 1.42 0.544 57 1616 exclusion phecode
117 Mycoses Infectious Diseases 1.17 0.993 – 1.39 0.0599 164 1439 exclusion phecode
117.1 Histoplasmosis Infectious Diseases 1.27 0.815 – 1.99 0.287 23 193 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.37 1.02 – 1.84 0.039 49 340 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.83 0.622 – 1.11 0.206 48 434 exclusion phecode
130.1 Lyme disease Infectious Diseases 0.766 0.549 – 1.07 0.117 38 309 exclusion phecode
131 Protozoan infection Infectious Diseases 1.42 0.815 – 2.48 0.215 11 163 exclusion phecode
132 Infestation (lice, mites) Infectious Diseases 1.2 0.892 – 1.62 0.228 46 468 exclusion phecode
134 Helminthiases Infectious Diseases 1.17 0.739 – 1.84 0.509 22 177 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.39 0.804 – 2.41 0.239 16 108 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.13 1.05 – 1.21 0.00135 854 7457 exclusion phecode
145 Cancer of mouth Neoplasms 1.27 1.14 – 1.42 1.03e-05 402 2723 exclusion phecode
145.1 Cancer of lip Neoplasms 1.55 0.968 – 2.49 0.0681 16 137 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.2 1.03 – 1.41 0.0227 186 1121 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.996 0.79 – 1.26 0.97 79 717 exclusion phecode
145.4 Cancer of the gums Neoplasms 1.62 1.2 – 2.2 0.00181 54 343 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.58 1.22 – 2.06 0.000633 75 363 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.28 1.14 – 1.44 2.24e-05 355 2312 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.42 1.13 – 1.78 0.00222 105 568 exclusion phecode
149.2 Cancer of nasopharynx Neoplasms 1.43 0.97 – 2.11 0.0708 33 211 exclusion phecode
149.3 Cancer of hypopharynx Neoplasms 1.44 0.943 – 2.19 0.0915 28 154 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.36 1.1 – 1.69 0.00457 102 636 exclusion phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 1.38 1.16 – 1.65 0.000376 148 971 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.12 0.835 – 1.5 0.454 60 466 exclusion phecode
150 Cancer of esophagus Neoplasms 1.48 1.2 – 1.83 0.000217 99 751 exclusion phecode
151 Cancer of stomach Neoplasms 1.14 0.926 – 1.4 0.219 112 884 exclusion phecode
153 Colorectal cancer Neoplasms 1.1 0.972 – 1.23 0.136 307 2977 exclusion phecode
153.2 Colon cancer Neoplasms 1.1 0.954 – 1.26 0.192 224 2327 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.04 0.893 – 1.21 0.62 194 1749 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.12 0.912 – 1.37 0.28 109 958 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.21 0.935 – 1.55 0.15 72 634 exclusion phecode
157 Pancreatic cancer Neoplasms 1.21 0.99 – 1.48 0.0621 119 943 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.05 0.939 – 1.18 0.385 366 3192 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.14 1.03 – 1.27 0.0158 398 3485 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.904 0.652 – 1.25 0.544 44 428 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.28 0.927 – 1.77 0.134 44 300 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.15 0.902 – 1.46 0.26 74 624 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.886 0.628 – 1.25 0.49 36 255 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.17 1.04 – 1.32 0.00866 327 2562 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.13 0.99 – 1.29 0.0706 254 2026 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 1.13 1.02 – 1.24 0.0212 438 3720 exclusion phecode
170.1 Bone cancer Neoplasms 1.23 1.07 – 1.42 0.00477 205 1645 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1.11 0.984 – 1.25 0.0904 295 2650 exclusion phecode
172 Skin cancer Neoplasms 0.952 0.903 – 1 0.0703 2005 7136 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.907 0.849 – 0.968 0.00316 1183 6208 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.908 0.834 – 0.988 0.0256 622 5040 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.953 0.9 – 1.01 0.0947 1698 6245 exclusion phecode
172.21 Basal cell carcinoma Neoplasms 0.882 0.819 – 0.95 0.000897 900 4642 exclusion phecode
172.22 Squamous cell carcinoma Neoplasms 1.05 0.959 – 1.15 0.291 583 3196 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.894 0.797 – 1 0.057 363 2293 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.919 0.832 – 1.01 0.0937 472 3913 exclusion phecode
174 Breast cancer Neoplasms 0.859 0.797 – 0.925 6e-05 942 4018 exclusion phecode
174.1 Breast cancer [female] Neoplasms 0.866 0.803 – 0.934 0.000196 905 3840 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.874 0.81 – 0.943 0.000526 886 3818 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.703 0.537 – 0.92 0.0102 65 592 exclusion phecode
175 Acquired absence of breast Neoplasms 0.831 0.734 – 0.942 0.00369 301 2272 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1 0.906 – 1.11 0.964 442 3333 exclusion phecode
180.1 Cervical cancer Neoplasms 1.08 0.904 – 1.29 0.398 135 1295 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.953 0.851 – 1.07 0.401 356 2584 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.896 0.736 – 1.09 0.277 105 1877 exclusion phecode
184 Cancer of other female genital organs Neoplasms 0.992 0.879 – 1.12 0.9 313 2979 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.914 0.768 – 1.09 0.312 151 1504 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.935 0.767 – 1.14 0.503 120 1139 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.09 0.91 – 1.3 0.36 150 1531 exclusion phecode
185 Cancer of prostate Neoplasms 0.87 0.771 – 0.982 0.0239 399 1589 exclusion phecode
187 Cancer of other male genital organs Neoplasms 0.973 0.75 – 1.26 0.839 66 631 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.19 0.715 – 1.98 0.503 14 181 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.905 0.666 – 1.23 0.524 42 389 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.08 0.584 – 2.01 0.797 12 97 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.04 0.943 – 1.14 0.44 474 4570 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.09 0.941 – 1.25 0.259 217 2783 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.07 0.913 – 1.25 0.413 179 2436 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.26 0.902 – 1.77 0.175 43 421 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.04 0.916 – 1.17 0.574 307 2791 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.08 0.95 – 1.22 0.244 290 2565 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.21 0.997 – 1.48 0.0539 116 1178 exclusion phecode
190 Cancer of eye Neoplasms 1.09 0.779 – 1.52 0.62 44 274 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.09 0.959 – 1.24 0.188 257 2389 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.989 0.85 – 1.15 0.881 189 1564 exclusion phecode
191.11 Cancer of brain Neoplasms 1.03 0.878 – 1.21 0.707 166 1311 exclusion phecode
193 Thyroid cancer Neoplasms 1.13 0.973 – 1.32 0.108 180 2295 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.16 0.954 – 1.4 0.139 115 1361 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.03 0.982 – 1.07 0.248 3803 6337 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.02 0.977 – 1.07 0.34 3739 6336 exclusion phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1.27 1.12 – 1.45 0.000249 276 1686 exclusion phecode
196 Radiotherapy Neoplasms 0.984 0.898 – 1.08 0.731 560 3437 exclusion phecode
197 Chemotherapy Neoplasms 1.11 1.04 – 1.18 0.00159 1227 5333 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.14 1.07 – 1.21 0.000111 1285 5236 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.1 1.02 – 1.19 0.0119 840 4617 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.31 1.13 – 1.51 0.000238 218 1968 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.08 0.93 – 1.24 0.328 220 1681 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.18 1.01 – 1.38 0.0338 193 1429 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.19 1 – 1.41 0.049 154 1229 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.43 1.22 – 1.67 7.56e-06 188 1540 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.17 0.92 – 1.49 0.202 81 608 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.04 0.975 – 1.11 0.235 1222 6068 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.36 0.958 – 1.93 0.0858 30 219 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.21 1.07 – 1.38 0.00348 259 2376 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.17 0.854 – 1.62 0.323 43 384 exclusion phecode
201 Hodgkin's disease Neoplasms 1.57 1.17 – 2.11 0.00249 47 409 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.17 1.05 – 1.3 0.00479 375 3286 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.15 1.02 – 1.29 0.0216 318 2810 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.12 0.957 – 1.32 0.155 183 1510 exclusion phecode
202.22 Reticulosarcoma Neoplasms 1.13 0.801 – 1.58 0.496 36 352 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.19 0.841 – 1.69 0.324 38 319 exclusion phecode
204 Leukemia Neoplasms 1.15 0.974 – 1.37 0.0974 153 1343 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1.24 0.936 – 1.64 0.134 58 448 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.28 0.798 – 2.05 0.306 21 173 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.17 0.834 – 1.64 0.367 38 313 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.15 0.884 – 1.5 0.295 62 505 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 1.07 0.749 – 1.53 0.71 36 268 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.984 0.583 – 1.66 0.953 16 128 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.27 0.928 – 1.73 0.136 42 438 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1.01 0.959 – 1.06 0.75 2119 8346 exclusion phecode
209 Neuroendocrine tumors Neoplasms 1.07 0.784 – 1.46 0.668 41 515 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.985 0.896 – 1.08 0.762 499 4205 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.09 1.03 – 1.15 0.00232 1559 8697 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.2 1.09 – 1.33 0.000336 437 3952 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.09 0.98 – 1.21 0.117 415 3699 exclusion phecode
214 Lipoma Neoplasms 1.04 0.917 – 1.19 0.517 260 3192 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1 0.851 – 1.19 0.96 160 2008 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.02 0.958 – 1.09 0.486 1012 9144 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.884 0.845 – 0.924 5.99e-08 2817 8094 exclusion phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 1.25 0.91 – 1.72 0.167 45 416 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.808 0.733 – 0.89 1.75e-05 502 3752 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.801 0.723 – 0.887 1.96e-05 464 3438 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.891 0.833 – 0.953 0.000785 1154 4797 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.822 0.744 – 0.908 0.000121 461 4411 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.891 0.829 – 0.959 0.00195 944 4715 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.884 0.767 – 1.02 0.0891 226 2392 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.912 0.829 – 1 0.0587 506 4088 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.753 0.644 – 0.88 0.000354 182 1720 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.01 0.893 – 1.13 0.914 326 2723 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.915 0.771 – 1.09 0.309 161 1399 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.903 0.749 – 1.09 0.284 134 1127 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.2 1.06 – 1.36 0.00371 275 2764 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.14 0.987 – 1.31 0.075 213 2174 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.4 1.1 – 1.79 0.00647 71 639 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.988 0.869 – 1.12 0.856 259 3226 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.964 0.851 – 1.09 0.569 283 3878 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.12 0.872 – 1.45 0.367 63 965 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.935 0.793 – 1.1 0.429 157 1863 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.853 0.659 – 1.1 0.226 63 1012 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.807 0.735 – 0.886 6.51e-06 538 4535 exclusion phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.748 0.666 – 0.84 8.78e-07 355 2832 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.962 0.911 – 1.01 0.156 1669 8554 exclusion phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.961 0.903 – 1.02 0.205 1210 7778 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.07 0.929 – 1.23 0.346 219 2530 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.04 0.949 – 1.13 0.437 605 5567 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.998 0.905 – 1.1 0.964 475 4945 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.01 0.884 – 1.16 0.848 236 3181 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.05 0.929 – 1.18 0.452 299 3335 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.931 0.771 – 1.12 0.455 118 1249 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.05 0.659 – 1.68 0.83 19 307 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.909 0.713 – 1.16 0.443 72 698 exclusion phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.971 0.694 – 1.36 0.866 38 356 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.05 0.996 – 1.12 0.0688 1647 7677 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.99 0.886 – 1.11 0.858 351 4262 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.03 0.912 – 1.17 0.621 284 3037 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.05 0.993 – 1.12 0.0826 1538 7562 exclusion phecode
245 Thyroiditis Endocrine/metabolic 1.2 1.02 – 1.4 0.0263 178 2110 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.25 1.05 – 1.5 0.0139 138 1770 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.24 1.04 – 1.49 0.0183 137 1751 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.04 0.978 – 1.11 0.209 1301 7120 exclusion phecode
246.2 Thyroid cyst Endocrine/metabolic 0.891 0.596 – 1.33 0.574 25 228 exclusion phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1.04 0.905 – 1.2 0.568 218 2156 exclusion phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.24 1.02 – 1.49 0.0272 169 1894 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.1 1.04 – 1.16 0.00147 1798 8752 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.16 1.01 – 1.34 0.042 469 2920 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.5 1.05 – 2.15 0.0252 103 226 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.18 0.928 – 1.49 0.178 154 616 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.48 1.15 – 1.9 0.00224 189 705 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.41 1.1 – 1.8 0.00599 160 588 exclusion phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 1.16 0.811 – 1.66 0.415 49 173 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.14 1.06 – 1.23 0.000616 1078 7827 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.54 1.05 – 2.27 0.0277 77 288 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.44 1.21 – 1.73 6.21e-05 173 3130 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.21 1 – 1.47 0.0471 207 2284 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.23 1.03 – 1.46 0.0203 215 3893 exclusion phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.1 0.857 – 1.42 0.448 71 1331 exclusion phecode
250.3 Insulin pump user Endocrine/metabolic 1.22 1.06 – 1.39 0.00431 438 5081 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.06 0.992 – 1.14 0.0841 1238 8248 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.934 0.806 – 1.08 0.36 232 4125 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.08 1 – 1.16 0.0489 1125 7996 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.91 1.18 – 3.11 0.00887 26 290 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.32 1.09 – 1.59 0.00471 205 3102 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.16 0.999 – 1.34 0.0513 256 2093 exclusion phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.15 1 – 1.32 0.0502 245 1974 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.19 1.04 – 1.38 0.0136 310 2348 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.09 0.991 – 1.2 0.0743 477 5165 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.07 0.969 – 1.19 0.178 435 4715 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.16 0.945 – 1.43 0.154 98 1179 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.984 0.837 – 1.16 0.85 164 1895 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.05 0.775 – 1.43 0.746 48 670 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.762 0.429 – 1.35 0.352 11 203 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.742 0.531 – 1.04 0.0811 32 477 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.34 0.831 – 2.16 0.23 15 182 exclusion phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 0.853 0.51 – 1.43 0.544 18 220 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.15 0.794 – 1.68 0.454 30 242 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.19 1.05 – 1.35 0.00584 276 3379 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.03 0.789 – 1.34 0.83 56 924 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.781 0.528 – 1.15 0.215 26 495 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.31 0.83 – 2.07 0.245 15 281 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.2 1 – 1.44 0.0502 131 1432 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.2 0.993 – 1.44 0.059 123 1361 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.886 0.773 – 1.02 0.0822 237 3240 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.769 0.61 – 0.969 0.0259 78 2257 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 0.981 0.817 – 1.18 0.833 127 1530 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.977 0.811 – 1.18 0.803 122 1469 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.28 0.777 – 2.1 0.333 17 186 exclusion phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.888 0.61 – 1.29 0.533 31 330 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.971 0.839 – 1.12 0.695 201 2439 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.25 1.17 – 1.34 3.56e-10 988 5553 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.36 1.12 – 1.65 0.00218 147 559 exclusion phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.4 1.28 – 1.53 3.56e-13 600 3325 exclusion phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.46 1.25 – 1.7 1.45e-06 214 1201 exclusion phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.35 1.15 – 1.57 0.000156 210 1199 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.27 1.11 – 1.45 0.000438 264 1878 exclusion phecode
260.7 Polyphagia Endocrine/metabolic 0.71 0.428 – 1.18 0.184 16 167 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.12 1.06 – 1.19 6.22e-05 1599 8182 exclusion phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1.81 1.14 – 2.87 0.0115 22 160 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.31 1.12 – 1.53 0.000888 175 1833 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.11 1.05 – 1.18 0.000237 1500 8199 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.26 0.724 – 2.2 0.412 14 118 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.22 1.07 – 1.38 0.00264 269 2874 exclusion phecode
263 Other nutritional deficiency Endocrine/metabolic 1.14 1.02 – 1.27 0.0187 368 3637 exclusion phecode
264 Lack of normal physiological development Endocrine/metabolic 1.06 0.854 – 1.31 0.6 103 699 exclusion phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.17 0.865 – 1.58 0.31 51 309 exclusion phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 0.874 0.617 – 1.24 0.451 38 286 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.35 1.19 – 1.53 2.9e-06 286 3036 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.16 0.999 – 1.35 0.0509 201 2098 exclusion phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.902 0.631 – 1.29 0.572 34 418 exclusion phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.827 0.561 – 1.22 0.337 29 348 exclusion phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 1.24 0.713 – 2.15 0.448 10 223 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.25 1.05 – 1.47 0.00999 164 1518 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.14 0.885 – 1.46 0.313 72 737 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 0.787 0.481 – 1.29 0.34 19 142 exclusion phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 1.1 0.583 – 2.08 0.766 18 134 exclusion phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.41 1.11 – 1.81 0.00582 76 663 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.993 0.897 – 1.1 0.888 417 6296 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.981 0.883 – 1.09 0.713 394 6130 exclusion phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.31 0.854 – 2 0.217 26 230 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.05 0.996 – 1.1 0.0695 2862 7532 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.05 0.996 – 1.1 0.0739 2851 7518 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.01 0.933 – 1.09 0.856 885 5677 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.905 0.748 – 1.09 0.301 112 2933 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.999 0.898 – 1.11 0.981 426 4669 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.952 0.729 – 1.24 0.717 61 737 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.13 1 – 1.29 0.0501 266 4357 exclusion phecode
274.1 Gout Endocrine/metabolic 1.16 1.02 – 1.33 0.0275 232 4169 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.17 0.965 – 1.43 0.108 106 2021 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.855 0.623 – 1.17 0.335 44 379 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.895 0.654 – 1.23 0.489 43 358 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.18 1.1 – 1.27 1.68e-06 945 8233 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.944 0.633 – 1.41 0.78 27 469 exclusion phecode
275.11 Hereditary hemochromatosis Hematopoietic 1.24 0.582 – 2.63 0.58 7 203 exclusion phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 1.82 0.987 – 3.37 0.0553 15 153 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.39 1.23 – 1.59 3.82e-07 273 2426 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.15 1.06 – 1.24 0.000536 738 7005 exclusion phecode
275.51 Hypocalcemia Endocrine/metabolic 1.32 1.14 – 1.53 0.000158 218 1971 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.23 1.09 – 1.38 0.00077 320 2783 exclusion phecode
275.6 Hypercalcemia Endocrine/metabolic 1.13 1 – 1.28 0.0456 290 3120 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.26 1.19 – 1.32 1.17e-18 2041 8801 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.31 1.23 – 1.39 2.05e-18 1364 7723 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.24 1.02 – 1.51 0.03 127 1035 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.34 1.23 – 1.46 5.07e-11 637 4587 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.36 1.25 – 1.49 2.28e-12 600 5079 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.34 1.21 – 1.48 1.55e-08 444 4590 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.26 1.13 – 1.39 1.03e-05 443 4136 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.28 1.15 – 1.43 1.2e-05 371 3556 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.33 1.1 – 1.63 0.00423 124 982 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.25 1.17 – 1.33 2.16e-11 1141 7954 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.48 1.29 – 1.7 3.72e-08 239 2587 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 0.894 0.605 – 1.32 0.573 24 289 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.08 1 – 1.17 0.0472 701 8379 exclusion phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.3 0.911 – 1.87 0.147 28 771 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.982 0.833 – 1.16 0.83 161 1518 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.918 0.77 – 1.09 0.338 143 2051 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.917 0.751 – 1.12 0.392 109 1709 exclusion phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.32 0.866 – 2.01 0.197 17 1926 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.23 1.14 – 1.34 2.44e-07 678 10325 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.47 1.27 – 1.71 4.83e-07 177 10321 exclusion phecode
278.11 Morbid obesity Endocrine/metabolic 1.99 1.48 – 2.69 6.74e-06 40 10260 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 1.27 0.904 – 1.78 0.168 31 1298 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.14 1.01 – 1.28 0.0328 307 7284 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.12 1.04 – 1.2 0.00398 806 6578 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.15 1.02 – 1.29 0.0212 328 2565 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.11 0.886 – 1.39 0.365 93 720 exclusion phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 1.02 0.873 – 1.18 0.835 198 1809 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.03 0.97 – 1.1 0.307 1119 8305 exclusion phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 1.05 0.896 – 1.24 0.529 171 1473 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.17 1.09 – 1.24 6.06e-06 1078 7054 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.17 1.09 – 1.25 6.56e-06 1043 7020 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.18 1.06 – 1.31 0.00184 408 3775 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.14 0.935 – 1.39 0.195 116 1161 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.09 0.827 – 1.43 0.541 62 579 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.09 0.715 – 1.67 0.682 28 267 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.02 0.727 – 1.44 0.89 43 434 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.13 0.871 – 1.46 0.362 63 652 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.17 0.909 – 1.51 0.222 69 693 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.06 0.773 – 1.46 0.713 46 437 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.46 1.05 – 2.04 0.0252 38 411 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.33 0.933 – 1.91 0.114 33 345 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.9 0.531 – 1.53 0.697 15 152 exclusion phecode
284 Aplastic anemia Hematopoietic 1.26 1.07 – 1.47 0.00439 181 1365 exclusion phecode
284.1 Pancytopenia Hematopoietic 1.31 1.11 – 1.56 0.00195 157 1208 exclusion phecode
285 Other anemias Hematopoietic 1.18 1.13 – 1.23 6.16e-13 2829 7835 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.21 1.12 – 1.31 5.86e-07 806 5912 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.4 1.27 – 1.54 2.69e-12 523 4091 exclusion phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.4 1.22 – 1.61 2.23e-06 221 1743 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.32 1.13 – 1.55 0.000589 182 1437 exclusion phecode
286 Coagulation defects Hematopoietic 1.1 1.02 – 1.19 0.0113 767 7586 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.77 0.572 – 1.04 0.0838 50 594 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.797 0.514 – 1.24 0.311 20 197 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.8 0.523 – 1.22 0.302 22 307 exclusion phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.11 1.01 – 1.21 0.0263 550 5391 exclusion phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 1.37 0.925 – 2.04 0.116 34 325 exclusion phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 1.08 0.813 – 1.43 0.601 50 500 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.953 0.665 – 1.37 0.795 24 279 exclusion phecode
286.6 Defibrination syndrome Hematopoietic 1.08 0.98 – 1.18 0.124 491 5592 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.08 0.987 – 1.17 0.0944 588 6545 exclusion phecode
286.8 Hypercoagulable state Hematopoietic 1.1 0.932 – 1.3 0.256 158 1963 exclusion phecode
286.81 Primary hypercoagulable state Hematopoietic 1.1 0.923 – 1.31 0.29 150 1863 exclusion phecode
286.9 Abnormal coagulation profile Hematopoietic 1.31 1.14 – 1.5 0.00016 224 2405 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.15 1.06 – 1.24 0.000401 740 6201 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.724 0.545 – 0.963 0.0262 55 491 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.18 1.08 – 1.28 9.77e-05 671 5659 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.18 0.975 – 1.43 0.089 119 1303 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.22 1.02 – 1.47 0.0309 135 1209 exclusion phecode
287.4 Qualitative platelet defects Hematopoietic 1.04 0.69 – 1.57 0.851 23 267 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.13 1.06 – 1.2 0.000209 1201 8361 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.13 1.03 – 1.24 0.0107 515 3506 exclusion phecode
288.11 Neutropenia Hematopoietic 1.22 1.08 – 1.37 0.000946 341 2383 exclusion phecode
288.2 Elevated white blood cell count Hematopoietic 1.11 1.04 – 1.19 0.00228 962 7794 exclusion phecode
288.3 Eosinophilia Hematopoietic 0.894 0.649 – 1.23 0.494 46 411 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.17 1.05 – 1.29 0.00326 440 3991 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.08 0.936 – 1.24 0.302 232 2168 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.04 0.975 – 1.12 0.214 946 7908 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1.19 0.939 – 1.51 0.151 79 834 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.39 1 – 1.93 0.0496 40 463 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.51 1.21 – 1.88 0.000282 99 843 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.13 1.01 – 1.27 0.0402 326 2192 exclusion phecode
290.1 Dementias Mental Disorders 0.92 0.757 – 1.12 0.399 116 945 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.93 0.636 – 1.36 0.708 32 269 exclusion phecode
290.12 Dementia with cerebral degenerations Mental Disorders 0.889 0.526 – 1.5 0.662 15 151 exclusion phecode
290.13 Senile dementia Mental Disorders 0.917 0.717 – 1.17 0.489 75 604 exclusion phecode
290.16 Vascular dementia Mental Disorders 1.04 0.625 – 1.73 0.883 20 144 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.17 1.01 – 1.37 0.0399 200 1357 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.935 0.809 – 1.08 0.36 208 1877 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.13 1.03 – 1.23 0.00981 540 5706 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.76 0.544 – 1.06 0.108 36 500 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.12 0.933 – 1.34 0.229 135 1160 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.14 1.02 – 1.26 0.0169 404 4403 exclusion phecode
292 Neurological disorders Mental Disorders 1.08 1.02 – 1.15 0.00914 1340 8914 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.14 1.04 – 1.25 0.0069 514 4104 exclusion phecode
292.11 Aphasia Mental Disorders 0.981 0.831 – 1.16 0.82 158 1414 exclusion phecode
292.12 Symbolic dysfunction Mental Disorders 0.907 0.668 – 1.23 0.533 45 448 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.956 0.763 – 1.2 0.698 83 779 exclusion phecode
292.3 Memory loss Mental Disorders 0.93 0.837 – 1.03 0.175 394 3874 exclusion phecode
292.4 Altered mental status Mental Disorders 1.2 1.1 – 1.32 7.04e-05 544 4644 exclusion phecode
292.5 Transient alteration of awareness Mental Disorders 1.05 0.858 – 1.27 0.657 105 944 exclusion phecode
292.6 Hallucinations Mental Disorders 1.35 0.985 – 1.84 0.0624 50 472 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.2 0.975 – 1.47 0.0861 109 942 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.09 1.02 – 1.16 0.0121 1033 8730 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.14 0.985 – 1.32 0.0781 211 1890 exclusion phecode
295.1 Schizophrenia Mental Disorders 0.904 0.636 – 1.28 0.573 30 327 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.19 0.788 – 1.81 0.405 24 252 exclusion phecode
295.3 Psychosis Mental Disorders 1.19 1.02 – 1.4 0.032 175 1527 exclusion phecode
296 Mood disorders Mental Disorders 1.09 1.04 – 1.14 0.000335 3358 5135 exclusion phecode
296.1 Bipolar Mental Disorders 1.22 1.07 – 1.38 0.00233 288 3055 exclusion phecode
296.2 Depression Mental Disorders 1.08 1.03 – 1.13 0.00115 3217 5134 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.09 1.04 – 1.14 0.000631 2978 5134 exclusion phecode
297 Suicidal ideation or attempt Mental Disorders 1.21 1.06 – 1.37 0.00435 273 2462 exclusion phecode
297.1 Suicidal ideation Mental Disorders 1.15 0.992 – 1.32 0.0643 211 2001 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.22 0.993 – 1.51 0.0585 99 768 exclusion phecode
300 Anxiety disorders Mental Disorders 1.11 1.06 – 1.16 4.77e-06 3742 5135 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.11 1.06 – 1.16 2.95e-06 3556 5135 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 1.07 1.01 – 1.14 0.0302 1339 4978 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.02 0.899 – 1.15 0.801 330 3115 exclusion phecode
300.13 Phobia Mental Disorders 1.18 1.02 – 1.36 0.0212 243 2450 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.809 0.639 – 1.02 0.0785 75 881 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.09 0.994 – 1.19 0.066 590 4164 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.07 0.863 – 1.32 0.55 103 1260 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.21 1.04 – 1.42 0.0144 192 2136 exclusion phecode
301 Personality disorders Mental Disorders 1.15 0.944 – 1.41 0.162 110 1340 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.14 0.88 – 1.48 0.318 64 700 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 0.941 0.857 – 1.03 0.199 544 2894 exclusion phecode
302.1 Decreased libido Mental Disorders 0.815 0.658 – 1.01 0.0597 97 1003 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.916 0.863 – 0.973 0.0045 1620 4752 exclusion phecode
303.1 Dissociative disorder Mental Disorders 1.29 0.896 – 1.87 0.17 32 423 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.912 0.857 – 0.969 0.00311 1550 4697 exclusion phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.77 0.63 – 0.941 0.0105 120 1144 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.979 0.865 – 1.11 0.733 312 3000 exclusion phecode
304 Adjustment reaction Mental Disorders 1.05 0.974 – 1.13 0.217 930 4959 exclusion phecode
305.2 Eating disorder Mental Disorders 1.18 0.991 – 1.4 0.0634 145 2340 exclusion phecode
306 Other mental disorder Mental Disorders 1.03 0.933 – 1.14 0.546 464 3668 exclusion phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.06 0.889 – 1.26 0.528 156 1234 exclusion phecode
306.9 Tension headache Mental Disorders 1.01 0.862 – 1.17 0.946 189 2011 exclusion phecode
312 Conduct disorders Mental Disorders 1.23 0.959 – 1.59 0.102 74 661 exclusion phecode
312.3 Impulse control disorder Mental Disorders 0.923 0.596 – 1.43 0.719 23 218 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 1.1 0.995 – 1.21 0.0627 467 4203 exclusion phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1.1 0.991 – 1.22 0.073 423 3835 exclusion phecode
313.2 Tics and stuttering Mental Disorders 1.19 0.775 – 1.82 0.43 23 217 exclusion phecode
313.3 Autism Mental Disorders 1.1 0.627 – 1.91 0.748 12 202 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.07 0.908 – 1.25 0.43 167 1581 exclusion phecode
315.1 Learning disorder Mental Disorders 1.05 0.704 – 1.56 0.821 25 273 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.986 0.758 – 1.28 0.915 62 604 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.32 1.23 – 1.42 2.81e-15 963 7539 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.08 0.912 – 1.28 0.371 153 1360 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.22 1.12 – 1.33 2.05e-06 671 4789 exclusion phecode
317.1 Alcoholism Mental Disorders 1.25 1.14 – 1.37 9.96e-07 561 3801 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.41 1.11 – 1.79 0.00465 81 651 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.36 1.29 – 1.43 1.54e-31 2004 8160 exclusion phecode
320 Meningitis Neurological 1.2 0.972 – 1.48 0.0905 101 872 exclusion phecode
323 Encephalitis Neurological 1.52 1.11 – 2.08 0.00876 45 392 exclusion phecode
323.8 Encephalitis, non-infectious Neurological 1.52 1.07 – 2.16 0.0185 39 330 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.06 0.802 – 1.4 0.681 52 626 exclusion phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 0.886 0.453 – 1.73 0.723 10 118 exclusion phecode
327 Sleep disorders Neurological 1.03 0.984 – 1.08 0.196 2171 8803 exclusion phecode
327.1 Hypersomnia Neurological 0.999 0.881 – 1.13 0.99 266 5126 exclusion phecode
327.3 Sleep apnea Neurological 1.01 0.941 – 1.08 0.796 898 8640 exclusion phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1.09 0.873 – 1.36 0.451 81 1103 exclusion phecode
327.32 Obstructive sleep apnea Neurological 0.989 0.911 – 1.07 0.795 639 8241 exclusion phecode
327.4 Insomnia Neurological 1.02 0.955 – 1.08 0.629 1270 8485 exclusion phecode
327.41 Organic or persistent insomnia Neurological 0.977 0.864 – 1.1 0.711 286 3274 exclusion phecode
327.5 Parasomnia Neurological 0.88 0.702 – 1.1 0.271 74 1455 exclusion phecode
327.6 Circadian rhythm sleep disorder Neurological 0.886 0.671 – 1.17 0.391 54 740 exclusion phecode
327.7 Sleep related movement disorders Neurological 1.01 0.896 – 1.14 0.881 304 4527 exclusion phecode
327.71 Restless legs syndrome Neurological 1.02 0.894 – 1.15 0.809 263 4037 exclusion phecode
327.72 Sleep related leg cramps Neurological 1.11 0.701 – 1.77 0.648 18 181 exclusion phecode
331 Other cerebral degenerations Neurological 1.2 1.02 – 1.4 0.0285 175 1452 exclusion phecode
331.1 Hydrocephalus Neurological 1.2 0.942 – 1.52 0.142 69 663 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.2 0.983 – 1.47 0.0729 105 817 exclusion phecode
332 Parkinson's disease Neurological 0.941 0.766 – 1.16 0.562 99 706 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.05 0.968 – 1.15 0.227 607 5909 exclusion phecode
333.1 Essential tremor Neurological 1.08 0.915 – 1.27 0.364 163 1443 exclusion phecode
333.2 Myoclonus Neurological 1.22 0.879 – 1.68 0.237 39 365 exclusion phecode
333.4 Torsion dystonia Neurological 0.991 0.81 – 1.21 0.928 113 785 exclusion phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 0.755 0.495 – 1.15 0.192 29 168 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.08 0.935 – 1.24 0.305 223 2251 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.52 0.951 – 2.44 0.0799 21 164 exclusion phecode
334.2 Anterior horn cell disease Neurological 1.16 0.752 – 1.8 0.5 25 213 exclusion phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 1.2 0.682 – 2.1 0.531 17 119 exclusion phecode
335 Multiple sclerosis Neurological 1.07 0.873 – 1.31 0.51 101 931 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.05 0.908 – 1.22 0.497 203 1628 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.35 1.05 – 1.72 0.0175 73 560 exclusion phecode
338 Pain Neurological 1.11 1.07 – 1.15 2.92e-07 4506 6507 exclusion phecode
338.1 Acute pain Neurological 1.12 1.07 – 1.17 1.14e-07 3556 6458 exclusion phecode
338.2 Chronic pain Neurological 1.13 1.08 – 1.19 1.56e-06 2162 6474 exclusion phecode
339 Other headache syndromes Neurological 1.04 0.986 – 1.09 0.162 2155 8099 exclusion phecode
340 Migraine Neurological 1.05 0.997 – 1.11 0.0634 1690 7395 exclusion phecode
340.1 Migrain with aura Neurological 1.08 1.01 – 1.16 0.0313 915 6012 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.38 0.993 – 1.92 0.0551 34 302 exclusion phecode
342 Hemiplegia Neurological 1.19 0.983 – 1.45 0.0735 110 966 exclusion phecode
343 Infantile cerebral palsy Neurological 1.29 0.873 – 1.89 0.203 25 246 exclusion phecode
344 Other paralytic syndromes Neurological 1.24 1.05 – 1.46 0.0096 171 1436 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.11 1.02 – 1.2 0.0118 654 5981 exclusion phecode
345.1 Epilepsy Neurological 1.12 0.966 – 1.3 0.135 194 1787 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.08 0.832 – 1.41 0.556 57 582 exclusion phecode
345.12 Partial epilepsy Neurological 1.07 0.895 – 1.28 0.463 138 1235 exclusion phecode
345.3 Convulsions Neurological 1.13 1.04 – 1.22 0.00564 620 5634 exclusion phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 1.05 0.755 – 1.46 0.77 40 423 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.09 0.97 – 1.22 0.15 338 3127 exclusion phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.922 0.627 – 1.36 0.682 28 262 exclusion phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 1.26 0.798 – 1.99 0.32 19 257 exclusion phecode
347 Cataplexy and narcolepsy Neurological 1.02 0.653 – 1.61 0.917 20 250 exclusion phecode
348 Other conditions of brain Neurological 1.11 1 – 1.23 0.0466 425 4047 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.01 0.878 – 1.16 0.878 215 2071 exclusion phecode
348.4 Cerebral cysts Neurological 0.811 0.616 – 1.07 0.133 53 566 exclusion phecode
348.7 Coma Neurological 1.32 1.01 – 1.73 0.043 57 529 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.39 1.2 – 1.62 1.82e-05 195 1750 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.1 1 – 1.2 0.049 532 5180 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.13 0.982 – 1.29 0.0891 234 2163 exclusion phecode
350 Abnormal movement Neurological 1.05 0.992 – 1.11 0.0957 1494 9072 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.07 0.986 – 1.15 0.109 750 6804 exclusion phecode
350.2 Abnormality of gait Neurological 1.02 0.948 – 1.1 0.571 815 6558 exclusion phecode
350.3 Lack of coordination Neurological 1.04 0.921 – 1.17 0.53 293 2332 exclusion phecode
350.5 Abnormal reflex Neurological 1.2 0.873 – 1.65 0.259 43 453 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.883 0.726 – 1.07 0.211 118 1103 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.05 0.99 – 1.11 0.102 1352 8345 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.09 0.979 – 1.21 0.115 379 4003 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.14 0.948 – 1.37 0.164 125 1317 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.06 0.905 – 1.25 0.451 161 1792 exclusion phecode
353 Nerve root and plexus disorders Neurological 1.07 1 – 1.16 0.0516 843 7874 exclusion phecode
353.1 Nerve plexus lesions Neurological 1.13 0.919 – 1.39 0.245 110 956 exclusion phecode
353.2 Nerve root lesions Neurological 1.23 0.8 – 1.88 0.349 24 257 exclusion phecode
355 Complex regional/central pain syndrome Neurological 1.18 0.985 – 1.41 0.0727 131 1290 exclusion phecode
355.1 Chronic pain syndrome Neurological 1.15 0.99 – 1.35 0.0674 181 1965 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.11 1 – 1.23 0.0506 395 4283 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.12 1.03 – 1.22 0.00737 623 6312 exclusion phecode
358 Myoneural disorders Neurological 1.14 0.997 – 1.31 0.0548 248 2514 exclusion phecode
358.1 Myasthenia gravis Neurological 0.778 0.516 – 1.17 0.23 26 245 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.911 0.807 – 1.03 0.13 309 2559 exclusion phecode
359.1 Muscular dystrophies Neurological 0.925 0.568 – 1.51 0.754 22 153 exclusion phecode
359.2 Myopathy Neurological 0.91 0.805 – 1.03 0.134 294 2454 exclusion phecode
360 Disorders of the globe Sense Organs 0.789 0.542 – 1.15 0.217 30 266 exclusion phecode
360.2 Progressive myopia Sense Organs 0.687 0.432 – 1.09 0.114 19 128 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.958 0.812 – 1.13 0.611 156 1427 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.912 0.704 – 1.18 0.488 65 551 exclusion phecode
362 Other retinal disorders Sense Organs 0.975 0.899 – 1.06 0.532 747 4729 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.888 0.801 – 0.985 0.0244 450 3086 exclusion phecode
362.21 Macular degeneration, dry Sense Organs 0.884 0.698 – 1.12 0.306 89 722 exclusion phecode
362.22 Macular degeneration, wet Sense Organs 0.726 0.485 – 1.09 0.121 34 253 exclusion phecode
362.23 Cystoid macular degeneration of retina Sense Organs 0.879 0.708 – 1.09 0.244 88 800 exclusion phecode
362.26 Macular puckering of retina Sense Organs 0.863 0.736 – 1.01 0.068 173 1667 exclusion phecode
362.27 Drusen (degenerative) of retina Sense Organs 1.02 0.838 – 1.25 0.815 114 930 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.889 0.798 – 0.991 0.0338 403 2769 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.07 0.912 – 1.25 0.415 174 1727 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1.17 0.944 – 1.45 0.151 87 771 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.909 0.758 – 1.09 0.301 134 1199 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.97 0.782 – 1.2 0.781 97 793 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.16 0.872 – 1.53 0.314 50 491 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1 0.763 – 1.32 0.983 62 476 exclusion phecode
362.9 Retinal edema Sense Organs 1.09 0.826 – 1.43 0.549 59 565 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.924 0.758 – 1.13 0.436 114 962 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.854 0.673 – 1.09 0.197 73 644 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.928 0.817 – 1.05 0.246 283 2369 exclusion phecode
364.1 Corneal opacity Sense Organs 0.762 0.616 – 0.942 0.0121 104 821 exclusion phecode
364.2 Corneal edema Sense Organs 0.947 0.61 – 1.47 0.807 22 244 exclusion phecode
364.4 Corneal degenerations Sense Organs 0.915 0.751 – 1.11 0.375 118 907 exclusion phecode
364.41 Keratoconus Sense Organs 0.576 0.345 – 0.964 0.0357 21 155 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.964 0.789 – 1.18 0.717 106 998 exclusion phecode
364.51 Fuchs' dystrophy Sense Organs 1.08 0.818 – 1.43 0.585 60 530 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.716 0.43 – 1.19 0.198 17 188 exclusion phecode
365 Glaucoma Sense Organs 0.916 0.837 – 1 0.0572 573 4343 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 0.928 0.784 – 1.1 0.382 166 1308 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.86 0.68 – 1.09 0.21 93 729 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.884 0.672 – 1.16 0.378 67 484 exclusion phecode
366 Cataract Sense Organs 0.98 0.924 – 1.04 0.504 1738 5909 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.913 0.691 – 1.21 0.523 56 430 exclusion phecode
366.2 Senile cataract Sense Organs 0.954 0.889 – 1.02 0.198 1076 5140 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.929 0.884 – 0.977 0.00427 2073 8929 exclusion phecode
367.1 Myopia Sense Organs 0.881 0.828 – 0.938 7.04e-05 1236 8271 exclusion phecode
367.2 Astigmatism Sense Organs 0.903 0.842 – 0.968 0.00399 963 7507 exclusion phecode
367.8 Hypermetropia Sense Organs 0.937 0.848 – 1.04 0.203 439 4193 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.05 0.929 – 1.2 0.413 276 2785 exclusion phecode
368 Visual disturbances Sense Organs 0.99 0.932 – 1.05 0.732 1304 9189 exclusion phecode
368.1 Amblyopia Sense Organs 1.09 0.914 – 1.3 0.336 142 1495 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.02 0.892 – 1.16 0.796 257 2306 exclusion phecode
368.3 Anisometropia Sense Organs 0.933 0.709 – 1.23 0.621 57 494 exclusion phecode
368.4 Visual field defects Sense Organs 0.938 0.813 – 1.08 0.383 202 2398 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.915 0.801 – 1.04 0.189 246 2456 exclusion phecode
368.91 Psychophysical visual disturbances Sense Organs 1.14 0.767 – 1.68 0.525 30 248 exclusion phecode
369 Infection of the eye Sense Organs 0.874 0.81 – 0.944 0.000621 768 6955 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.87 0.718 – 1.05 0.153 126 1209 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.868 0.798 – 0.943 0.000818 653 6187 exclusion phecode
370 Keratitis Sense Organs 0.832 0.744 – 0.93 0.00118 363 3031 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.757 0.583 – 0.983 0.0369 73 497 exclusion phecode
370.2 Superficial keratitis Sense Organs 0.819 0.685 – 0.98 0.0289 135 1226 exclusion phecode
370.3 Keratoconjunctivitis Sense Organs 0.955 0.813 – 1.12 0.572 170 1469 exclusion phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.757 0.564 – 1.02 0.0642 51 429 exclusion phecode
371 Inflammation of the eye Sense Organs 0.938 0.878 – 1 0.0623 1061 7190 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.993 0.825 – 1.2 0.941 126 1173 exclusion phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.956 0.828 – 1.1 0.54 208 2101 exclusion phecode
371.21 Allergic conjunctivitis Sense Organs 0.933 0.796 – 1.09 0.389 171 1761 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.923 0.856 – 0.996 0.0384 827 5881 exclusion phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 1.12 0.8 – 1.57 0.508 45 323 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.04 0.911 – 1.18 0.599 270 2280 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.927 0.853 – 1.01 0.0742 666 5197 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.884 0.721 – 1.08 0.238 104 867 exclusion phecode
374.2 Lagophthalmos Sense Organs 1.22 0.953 – 1.57 0.115 71 518 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.985 0.862 – 1.13 0.829 248 2311 exclusion phecode
374.6 Dermatochalasis Sense Organs 0.957 0.824 – 1.11 0.561 193 2010 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.959 0.891 – 1.03 0.26 897 5809 exclusion phecode
375.1 Dry eyes Sense Organs 0.959 0.893 – 1.03 0.252 970 5921 exclusion phecode
375.2 Epiphora Sense Organs 0.895 0.734 – 1.09 0.27 109 943 exclusion phecode
376 Disorders of the orbit Sense Organs 1.13 0.914 – 1.4 0.256 85 816 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.996 0.856 – 1.16 0.954 187 2041 exclusion phecode
377.1 Optic atrophy Sense Organs 0.911 0.696 – 1.19 0.497 61 600 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.07 0.883 – 1.3 0.489 118 1325 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.14 1.01 – 1.28 0.0345 308 2832 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.07 0.925 – 1.24 0.354 195 1886 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.21 0.897 – 1.64 0.211 44 362 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.08 0.849 – 1.36 0.547 83 745 exclusion phecode
379 Other disorders of eye Sense Organs 0.955 0.893 – 1.02 0.179 1109 6488 exclusion phecode
379.1 Scleritis and episcleritis Sense Organs 0.877 0.639 – 1.2 0.417 45 414 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.945 0.873 – 1.02 0.162 783 4805 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.848 0.577 – 1.25 0.403 38 278 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 0.991 0.765 – 1.28 0.948 62 614 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.08 0.841 – 1.38 0.555 73 591 exclusion phecode
379.51 Pigmentary iris degeneration Sense Organs 0.779 0.468 – 1.3 0.336 18 138 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.895 0.786 – 1.02 0.0935 268 2541 exclusion phecode
380 Disorders of external ear Sense Organs 0.9 0.821 – 0.986 0.0242 533 4433 exclusion phecode
380.1 Otitis externa Sense Organs 0.824 0.73 – 0.932 0.00198 292 3392 exclusion phecode
380.4 Impacted cerumen Sense Organs 0.876 0.804 – 0.954 0.00234 622 5170 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.989 0.925 – 1.06 0.754 984 8885 exclusion phecode
381.1 Otitis media Sense Organs 1.01 0.935 – 1.1 0.771 692 7540 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.02 0.931 – 1.11 0.724 570 6551 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.914 0.828 – 1.01 0.0725 456 4389 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.854 0.594 – 1.23 0.397 30 367 exclusion phecode
381.9 Otorrhea Sense Organs 1.18 0.937 – 1.48 0.161 82 892 exclusion phecode
382 Otalgia Sense Organs 0.972 0.882 – 1.07 0.564 473 4795 exclusion phecode
383 Otosclerosis Sense Organs 1.02 0.715 – 1.44 0.929 33 289 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.06 0.883 – 1.28 0.516 126 1334 exclusion phecode
384.1 Myringitis Sense Organs 0.832 0.455 – 1.52 0.552 13 126 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.07 0.872 – 1.32 0.508 100 1050 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.997 0.821 – 1.21 0.975 115 1063 exclusion phecode
385.3 Cholesteatoma Sense Organs 1.03 0.816 – 1.31 0.787 77 704 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1 0.724 – 1.39 0.979 42 313 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.872 0.783 – 0.971 0.0124 389 4144 exclusion phecode
386.1 Meniere's disease Sense Organs 0.821 0.643 – 1.05 0.115 69 699 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.865 0.767 – 0.975 0.0173 313 3465 exclusion phecode
386.21 Central origin vertigo Sense Organs 0.847 0.739 – 0.971 0.0173 239 2681 exclusion phecode
386.3 Labyrinthitis Sense Organs 0.852 0.755 – 0.961 0.00906 305 3323 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.993 0.939 – 1.05 0.816 1533 8939 exclusion phecode
388 Other disorders of ear Sense Organs 0.995 0.869 – 1.14 0.946 235 2220 exclusion phecode
389 Hearing loss Sense Organs 0.979 0.928 – 1.03 0.426 1750 9108 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.921 0.856 – 0.991 0.0271 866 6253 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.01 0.882 – 1.16 0.868 231 2287 exclusion phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 1.17 0.837 – 1.64 0.357 45 353 exclusion phecode
389.4 Tinnitus Sense Organs 0.998 0.911 – 1.09 0.959 536 4740 exclusion phecode
389.5 Disorders of acoustic nerve Sense Organs 1.29 0.906 – 1.83 0.159 35 268 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.1 0.978 – 1.24 0.111 313 2691 exclusion phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 0.884 0.688 – 1.14 0.333 71 628 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.06 0.864 – 1.3 0.583 103 958 exclusion phecode
394.3 Aortic valve disease Circulatory System 0.898 0.605 – 1.33 0.594 25 304 exclusion phecode
394.4 Acute rheumatic heart disease Circulatory System 1.27 0.709 – 2.29 0.418 11 124 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.12 0.94 – 1.34 0.204 146 1151 exclusion phecode
395 Heart valve disorders Circulatory System 1.1 1.02 – 1.18 0.00984 885 6001 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.04 0.948 – 1.14 0.416 538 4304 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.23 1.1 – 1.38 0.000213 378 3214 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.08 0.889 – 1.3 0.45 121 1016 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.26 0.848 – 1.88 0.251 29 245 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.2 1.04 – 1.39 0.015 205 2036 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.02 0.957 – 1.09 0.522 1089 7743 exclusion phecode
401 Hypertension Circulatory System 1.14 1.09 – 1.2 2.65e-08 3346 7626 exclusion phecode
401.1 Essential hypertension Circulatory System 1.14 1.09 – 1.2 6.63e-08 3302 7627 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.36 1.24 – 1.49 1.36e-10 559 4287 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.26 1.04 – 1.52 0.0188 115 1846 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.38 1.25 – 1.54 8.02e-10 433 3799 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.26 1.15 – 1.39 2.25e-06 489 4747 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.25 1.18 – 1.33 9.44e-13 1399 6875 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1 0.823 – 1.22 1 114 1634 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.29 1.18 – 1.42 2.47e-08 581 4475 exclusion phecode
411.3 Angina pectoris Circulatory System 1.23 1.1 – 1.38 0.000287 351 3742 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.25 1.17 – 1.34 1.02e-10 1170 6026 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.07 0.694 – 1.64 0.767 22 310 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.28 1.19 – 1.38 3.71e-11 935 5489 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.24 0.977 – 1.57 0.0768 78 862 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.18 1.08 – 1.29 0.000367 537 4888 exclusion phecode
414.2 ASCVD Circulatory System 1.07 0.877 – 1.31 0.496 105 1390 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.23 1.13 – 1.35 2.73e-06 568 6409 exclusion phecode
415.1 Acute pulmonary heart disease Circulatory System 1.2 1.06 – 1.35 0.00295 307 4016 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.2 1.06 – 1.35 0.00286 306 3996 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.3 1.15 – 1.45 1.24e-05 325 3624 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.38 1.16 – 1.65 0.000318 141 1459 exclusion phecode
416 Cardiomegaly Circulatory System 1.14 0.993 – 1.32 0.0631 223 2598 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.06 1.01 – 1.11 0.0142 2663 8303 exclusion phecode
418.1 Precordial pain Circulatory System 1 0.881 – 1.14 0.955 257 2916 exclusion phecode
420 Carditis Circulatory System 1.09 0.973 – 1.23 0.136 325 3199 exclusion phecode
420.1 Myocarditis Circulatory System 1.21 0.751 – 1.94 0.434 16 212 exclusion phecode
420.2 Pericarditis Circulatory System 1.03 0.874 – 1.21 0.747 176 1693 exclusion phecode
420.21 Acute pericarditis Circulatory System 0.925 0.68 – 1.26 0.622 43 368 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.15 0.711 – 1.85 0.572 21 235 exclusion phecode
420.3 Endocarditis Circulatory System 1.15 0.975 – 1.35 0.0962 162 1555 exclusion phecode
425 Cardiomyopathy Circulatory System 1.19 1.07 – 1.33 0.00154 365 3873 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.18 1.06 – 1.32 0.00363 347 3682 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.31 0.902 – 1.9 0.156 30 393 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.62 1.09 – 2.41 0.0164 26 421 exclusion phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.2 0.947 – 1.51 0.134 72 673 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.35 0.864 – 2.12 0.187 24 212 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.11 1.05 – 1.17 7.66e-05 2393 6433 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.13 0.994 – 1.28 0.061 282 2269 exclusion phecode
426.21 First degree AV block Circulatory System 1.08 0.92 – 1.27 0.346 184 1698 exclusion phecode
426.22 Mobitz II AV block Circulatory System 0.991 0.549 – 1.79 0.976 11 121 exclusion phecode
426.23 Second degree AV block Circulatory System 0.987 0.715 – 1.36 0.938 41 380 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1 0.791 – 1.27 0.995 85 744 exclusion phecode
426.25 Other heart block Circulatory System 1.27 0.905 – 1.78 0.168 38 337 exclusion phecode
426.3 Bundle branch block Circulatory System 1.12 1 – 1.25 0.0463 378 2927 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.06 0.927 – 1.22 0.381 235 2178 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.15 0.97 – 1.36 0.107 152 1610 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.874 0.588 – 1.3 0.506 24 216 exclusion phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.11 1.05 – 1.17 0.000166 2072 6305 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.24 1.03 – 1.48 0.0219 137 1431 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.18 1.04 – 1.33 0.00895 305 2302 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.22 1.05 – 1.43 0.0114 189 1569 exclusion phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.2 1.01 – 1.42 0.0371 150 1374 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.05 1 – 1.09 0.0298 3759 6569 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.08 0.983 – 1.19 0.11 517 4083 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.02 0.914 – 1.14 0.712 360 3264 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.16 1 – 1.34 0.0504 212 1952 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.07 0.989 – 1.16 0.0898 880 4073 exclusion phecode
427.21 Atrial fibrillation Circulatory System 1.07 0.987 – 1.16 0.0999 850 3984 exclusion phecode
427.22 Atrial flutter Circulatory System 0.997 0.876 – 1.13 0.962 270 2103 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.09 1.03 – 1.15 0.00289 1873 6497 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.941 0.752 – 1.18 0.599 89 1045 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.01 0.698 – 1.47 0.942 31 405 exclusion phecode
427.42 Cardiac arrest Circulatory System 0.988 0.774 – 1.26 0.921 76 797 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.05 0.984 – 1.11 0.147 1413 6465 exclusion phecode
427.6 Premature beats Circulatory System 0.928 0.837 – 1.03 0.151 451 3494 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 0.964 0.805 – 1.15 0.685 144 1322 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.13 1.06 – 1.2 0.000192 1198 6476 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.05 0.897 – 1.24 0.525 174 1536 exclusion phecode
427.9 Palpitations Circulatory System 0.919 0.859 – 0.983 0.0141 1079 6085 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.26 1.16 – 1.37 7.59e-08 692 5011 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.25 1.15 – 1.37 6.21e-07 592 4695 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.32 1.2 – 1.44 4.83e-09 568 4489 exclusion phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.29 1.15 – 1.46 2.34e-05 312 2812 exclusion phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.3 1.13 – 1.51 0.000328 207 2667 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.06 1.01 – 1.11 0.0188 2642 8036 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.25 1.09 – 1.43 0.00114 243 2297 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.14 1.07 – 1.22 9.65e-05 1140 6729 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.03 0.984 – 1.09 0.189 2144 7990 exclusion phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.19 0.985 – 1.44 0.0721 123 1402 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.05 0.903 – 1.23 0.502 183 1622 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.13 0.865 – 1.49 0.363 60 542 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.14 0.908 – 1.43 0.262 87 759 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.02 0.797 – 1.3 0.89 73 525 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.13 1.06 – 1.21 0.00018 1116 6795 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.15 1.04 – 1.28 0.00745 418 3096 exclusion phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 0.928 0.705 – 1.22 0.595 60 505 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 0.719 0.423 – 1.22 0.223 16 154 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.14 1.03 – 1.25 0.00801 482 4311 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.14 1.04 – 1.26 0.00788 467 4173 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.09 0.994 – 1.19 0.0661 558 4590 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.12 1.01 – 1.23 0.0272 483 4143 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.28 1.06 – 1.55 0.0119 123 1079 exclusion phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.2 0.948 – 1.52 0.13 76 904 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.12 0.942 – 1.34 0.196 139 1421 exclusion phecode
440 Atherosclerosis Circulatory System 1.17 1.06 – 1.29 0.00169 483 3834 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.03 0.776 – 1.37 0.839 53 473 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.08 0.958 – 1.23 0.199 289 2602 exclusion phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.55 1.17 – 2.07 0.00258 57 444 exclusion phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.05 0.909 – 1.22 0.482 202 1833 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.21 1.02 – 1.43 0.0269 146 1519 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.24 1.04 – 1.47 0.0161 141 1086 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.05 0.811 – 1.35 0.727 64 493 exclusion phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.23 0.922 – 1.65 0.156 49 341 exclusion phecode
442 Other aneurysm Circulatory System 1.16 1.06 – 1.27 0.00107 538 4204 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.18 1.05 – 1.31 0.00369 359 3044 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.14 0.989 – 1.32 0.0696 231 1842 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.11 0.733 – 1.68 0.62 26 331 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.26 0.855 – 1.86 0.243 26 317 exclusion phecode
442.4 Arterial dissection Circulatory System 0.766 0.551 – 1.07 0.114 41 360 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.17 0.941 – 1.45 0.158 97 829 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.12 1.03 – 1.21 0.00704 751 5181 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.02 0.896 – 1.16 0.78 299 1780 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.5 0.979 – 2.29 0.0624 25 321 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.13 1.04 – 1.23 0.00585 633 4524 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.19 1.07 – 1.31 0.000653 470 3653 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.17 1 – 1.36 0.0433 205 1687 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.06 0.844 – 1.34 0.598 85 563 exclusion phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 0.865 0.598 – 1.25 0.441 33 254 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.07 0.877 – 1.32 0.489 112 996 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.78 0.526 – 1.16 0.216 29 233 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.34 0.777 – 2.3 0.294 17 155 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.06 0.825 – 1.35 0.664 74 611 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.18 1.07 – 1.29 0.000502 541 4593 exclusion phecode
447.1 Stricture of artery Circulatory System 1.28 1.05 – 1.54 0.012 127 1103 exclusion phecode
447.7 Aortic ectasia Circulatory System 1.24 1.02 – 1.5 0.0287 110 1448 exclusion phecode
448 Disease of capillaries Circulatory System 0.877 0.781 – 0.986 0.0278 338 2641 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.06 0.96 – 1.17 0.248 431 4714 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.941 0.799 – 1.11 0.462 154 1664 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.998 0.726 – 1.37 0.99 39 565 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1.1 1.03 – 1.19 0.00548 915 7002 exclusion phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1.3 0.923 – 1.83 0.133 32 571 exclusion phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1.08 0.994 – 1.18 0.0696 596 6075 exclusion phecode
452.8 Postphlebitic syndrome Circulatory System 0.793 0.509 – 1.24 0.307 21 348 exclusion phecode
453 Chronic venous hypertension Circulatory System 0.915 0.671 – 1.25 0.577 47 476 exclusion phecode
454 Varicose veins Circulatory System 1.02 0.939 – 1.11 0.602 608 5675 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1.03 0.938 – 1.13 0.54 514 4894 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.966 0.858 – 1.09 0.563 316 3463 exclusion phecode
455 Hemorrhoids Circulatory System 0.938 0.882 – 0.998 0.0439 1282 6964 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.978 0.896 – 1.07 0.625 567 5684 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.11 0.991 – 1.24 0.0719 364 3134 exclusion phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.1 0.834 – 1.46 0.492 55 598 exclusion phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.1 0.982 – 1.23 0.098 336 2996 exclusion phecode
458 Hypotension Circulatory System 1.26 1.18 – 1.34 3.84e-12 1176 7346 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.14 1.02 – 1.29 0.0255 332 2790 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.28 1.11 – 1.46 0.000423 240 2177 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.26 1.18 – 1.35 2.13e-11 1063 7007 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.16 1.1 – 1.23 4.43e-07 1488 8249 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.15 0.992 – 1.34 0.0646 198 1796 exclusion phecode
459.7 Blood vessel replaced Circulatory System 1.25 1.1 – 1.42 0.00068 270 2697 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.13 1.06 – 1.2 0.000155 1216 7763 exclusion phecode
464 Acute sinusitis Respiratory 0.95 0.889 – 1.02 0.129 1058 7669 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.953 0.908 – 0.999 0.0467 2314 8379 exclusion phecode
465.2 Acute pharyngitis Respiratory 0.907 0.855 – 0.963 0.00128 1387 7845 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.06 0.859 – 1.31 0.586 99 1091 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.98 0.886 – 1.08 0.69 447 4242 exclusion phecode
471 Nasal polyps Respiratory 0.914 0.759 – 1.1 0.344 128 1347 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.873 0.784 – 0.973 0.0139 386 4089 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.11 1.02 – 1.2 0.0104 765 5620 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.63 0.937 – 2.85 0.0833 15 141 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.2 1.01 – 1.43 0.0422 152 1442 exclusion phecode
473.4 Voice disturbance Respiratory 1.13 1.03 – 1.23 0.00633 621 4837 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1.03 0.913 – 1.17 0.596 289 2465 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.09 0.905 – 1.32 0.358 129 1165 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.01 0.878 – 1.16 0.884 220 2021 exclusion phecode
475 Chronic sinusitis Respiratory 1.02 0.948 – 1.09 0.67 987 6534 exclusion phecode
475.9 Postnasal drip Respiratory 1 0.86 – 1.16 0.996 196 1995 exclusion phecode
476 Allergic rhinitis Respiratory 0.952 0.91 – 0.996 0.0329 2895 6585 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.12 0.985 – 1.27 0.084 266 2574 exclusion phecode
478 Throat pain Respiratory 1.16 0.954 – 1.41 0.137 120 1024 exclusion phecode
479 Other upper respiratory disease Respiratory 1.05 0.984 – 1.11 0.151 1311 6567 exclusion phecode
480 Pneumonia Respiratory 1.11 1.04 – 1.17 0.00098 1287 8722 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.09 0.974 – 1.23 0.127 309 2487 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.23 1.04 – 1.47 0.0183 139 1193 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.13 0.835 – 1.52 0.433 50 359 exclusion phecode
480.13 MRSA pneumonia Respiratory 1.62 1 – 2.62 0.0496 20 272 exclusion phecode
480.2 Viral pneumonia Respiratory 1.32 0.949 – 1.83 0.0994 41 379 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.33 0.978 – 1.81 0.0685 47 332 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.41 1.02 – 1.95 0.0393 39 297 exclusion phecode
481 Influenza Respiratory 1.03 0.912 – 1.16 0.628 298 3205 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.954 0.878 – 1.04 0.265 646 7069 exclusion phecode
495 Asthma Respiratory 1.09 1.04 – 1.15 0.00105 1770 8173 exclusion phecode
495.1 Chronic obstructive asthma Respiratory 1.29 1 – 1.66 0.0468 66 857 exclusion phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 0.763 0.337 – 1.72 0.516 8 159 exclusion phecode
495.2 Asthma with exacerbation Respiratory 0.979 0.871 – 1.1 0.714 321 4419 exclusion phecode
496 Chronic airway obstruction Respiratory 1.34 1.25 – 1.43 2.08e-18 1192 6161 exclusion phecode
496.1 Emphysema Respiratory 1.41 1.29 – 1.54 2.68e-13 559 3825 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.43 1.33 – 1.54 3.31e-20 840 5653 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.46 1.35 – 1.58 6.44e-21 770 5285 exclusion phecode
496.3 Bronchiectasis Respiratory 1.09 0.927 – 1.29 0.288 170 1143 exclusion phecode
497 Bronchitis Respiratory 1.07 0.955 – 1.19 0.256 365 4623 exclusion phecode
498 Acute bronchospasm Respiratory 1.28 1.03 – 1.58 0.0239 97 1271 exclusion phecode
499 Cystic fibrosis Respiratory 1.01 0.754 – 1.35 0.959 57 408 exclusion phecode
500 Lung disease due to external agents Respiratory 1.3 1.07 – 1.59 0.00794 122 1106 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.3 0.801 – 2.1 0.29 23 203 exclusion phecode
500.2 Pneumoconiosis Respiratory 1.68 0.755 – 3.74 0.203 10 121 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.45 1.23 – 1.72 1.76e-05 173 1183 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.09 0.927 – 1.28 0.296 165 1637 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.21 1.03 – 1.43 0.0198 164 1657 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.09 0.902 – 1.32 0.372 126 1197 exclusion phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 0.987 0.762 – 1.28 0.92 66 623 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.13 1.01 – 1.27 0.0304 342 3215 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.17 1.08 – 1.27 0.000128 701 5222 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.23 1.13 – 1.33 1.23e-06 659 5524 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.26 1.14 – 1.38 2.81e-06 475 4713 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.23 1.14 – 1.33 4.7e-08 808 6265 exclusion phecode
509.1 Respiratory failure Respiratory 1.39 1.26 – 1.55 4.54e-10 427 3812 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.21 1.06 – 1.38 0.00468 269 2349 exclusion phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.21 1.09 – 1.35 0.000475 385 3241 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.29 1.14 – 1.45 2.78e-05 317 3416 exclusion phecode
510 Other diseases of lung Respiratory 1.1 1.04 – 1.18 0.00197 1194 7846 exclusion phecode
510.2 Lung transplant Respiratory 1.35 0.992 – 1.83 0.0559 51 373 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.1 1.06 – 1.15 4.11e-06 3890 7132 exclusion phecode
512.1 Wheezing Respiratory 1.38 1.2 – 1.59 7.96e-06 215 3292 exclusion phecode
512.2 Painful respiration Respiratory 1.1 1 – 1.2 0.0423 552 5258 exclusion phecode
512.3 Abnormal chest sounds Respiratory 1.25 0.969 – 1.6 0.0868 73 608 exclusion phecode
512.7 Shortness of breath Respiratory 1.16 1.1 – 1.22 5.17e-08 1926 7104 exclusion phecode
512.8 Cough Respiratory 1.06 1.01 – 1.12 0.022 2033 7127 exclusion phecode
512.9 Other dyspnea Respiratory 1.13 1.07 – 1.19 5.03e-06 1997 7106 exclusion phecode
513 Respiratory abnormalities Respiratory 1.14 1.08 – 1.19 7.69e-08 2470 8537 exclusion phecode
513.3 Hypoventilation Respiratory 1.02 0.851 – 1.22 0.844 128 1878 exclusion phecode
513.31 Apnea Respiratory 1 0.787 – 1.27 0.997 76 960 exclusion phecode
513.32 Orthopnea Respiratory 1.05 0.731 – 1.5 0.8 28 412 exclusion phecode
513.4 Hyperventilation Respiratory 1.34 1.08 – 1.66 0.00895 94 1120 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.59 1.15 – 2.19 0.0051 40 488 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.14 1.07 – 1.21 5.96e-05 1193 7434 exclusion phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 0.936 0.703 – 1.25 0.649 52 543 exclusion phecode
514.2 Solitary pulmonary nodule Respiratory 1.12 1.03 – 1.21 0.00868 652 5644 exclusion phecode
516 Abnormal sputum Respiratory 1.17 0.992 – 1.37 0.0633 169 1494 exclusion phecode
516.1 Hemoptysis Respiratory 1.18 0.988 – 1.41 0.0676 137 1263 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.14 1.08 – 1.21 6.06e-06 1418 9074 exclusion phecode
519.1 Tracheostomy complications Respiratory 1.51 1.16 – 1.96 0.00206 64 431 exclusion phecode
519.2 Respiratory complications Respiratory 1.07 0.862 – 1.32 0.549 94 928 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.07 0.96 – 1.19 0.231 382 3472 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.19 1.11 – 1.27 3.14e-07 1037 7618 exclusion phecode
520 Disorders of tooth development Digestive 1.1 0.91 – 1.33 0.323 120 952 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.45 1.07 – 1.98 0.0179 52 380 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.985 0.782 – 1.24 0.896 77 638 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.43 1.25 – 1.64 2.13e-07 250 1935 exclusion phecode
521.1 Dental caries Digestive 1.44 1.25 – 1.65 3.6e-07 234 1781 exclusion phecode
521.2 Dental abrasion, erosion and attrition Digestive 1.01 0.54 – 1.9 0.969 8 116 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.4 1.15 – 1.7 0.00077 111 1178 exclusion phecode
522.5 Periapical abscess Digestive 1.56 1.26 – 1.94 5.3e-05 95 1040 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.33 1.13 – 1.57 0.000493 163 1547 exclusion phecode
523.1 Gingivitis Digestive 1.21 0.867 – 1.68 0.267 38 340 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.54 1.2 – 1.97 0.000665 71 779 exclusion phecode
523.31 Acute periodontitis Digestive 1.47 1.13 – 1.92 0.00407 56 663 exclusion phecode
523.32 Chronic periodontitis Digestive 1.58 1.06 – 2.35 0.0247 30 246 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.05 0.881 – 1.25 0.579 160 1055 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.991 0.803 – 1.22 0.936 110 683 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.4 1.24 – 1.59 1.59e-07 278 2423 exclusion phecode
525.1 Loss of teeth or edentulism Digestive 1.32 1.08 – 1.62 0.00741 105 894 exclusion phecode
526 Diseases of the jaws Digestive 1.04 0.964 – 1.12 0.32 817 6561 exclusion phecode
526.1 Cysts of the jaws Digestive 0.826 0.632 – 1.08 0.16 53 512 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.02 0.833 – 1.24 0.867 123 786 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 0.967 0.875 – 1.07 0.517 453 3884 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.972 0.87 – 1.09 0.611 371 3116 exclusion phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 0.996 0.866 – 1.15 0.958 237 2005 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 1.51 1.21 – 1.89 0.000226 104 654 exclusion phecode
526.8 Exostosis of jaw Digestive 1.73 1.04 – 2.88 0.0338 21 98 exclusion phecode
526.9 Jaw disease NOS Digestive 1.19 1.01 – 1.4 0.0412 173 1118 exclusion phecode
527 Diseases of the salivary glands Digestive 1.06 0.956 – 1.17 0.28 425 3834 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 0.987 0.593 – 1.64 0.96 14 141 exclusion phecode
527.2 Sialoadenitis Digestive 1.11 0.893 – 1.39 0.342 95 913 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.13 0.987 – 1.3 0.075 226 1880 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.02 0.764 – 1.35 0.908 54 529 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.06 0.982 – 1.15 0.132 751 5899 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.01 0.871 – 1.17 0.883 200 1559 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.12 0.834 – 1.49 0.46 51 490 exclusion phecode
528.12 Oral aphthae Digestive 0.856 0.669 – 1.09 0.215 69 559 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.63 1.28 – 2.08 8.98e-05 74 528 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.722 0.499 – 1.04 0.0836 33 296 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.785 0.499 – 1.24 0.295 23 176 exclusion phecode
528.5 Diseases of lips Digestive 1.09 0.913 – 1.31 0.334 142 1063 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.12 0.783 – 1.61 0.531 34 277 exclusion phecode
528.7 Sialolithiasis Digestive 1.19 0.876 – 1.62 0.263 44 339 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 0.955 0.81 – 1.13 0.585 156 1409 exclusion phecode
529.1 Glossitis Digestive 1.07 0.739 – 1.56 0.707 30 268 exclusion phecode
529.6 Glossodynia Digestive 0.827 0.577 – 1.19 0.302 30 321 exclusion phecode
530 Diseases of esophagus Digestive 1.16 1.11 – 1.21 2.3e-11 3202 7330 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.16 1.11 – 1.21 6.75e-11 3046 7330 exclusion phecode
530.11 GERD Digestive 1.16 1.11 – 1.22 6.68e-11 2914 7329 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.22 0.974 – 1.52 0.0843 84 907 exclusion phecode
530.13 Barrett's esophagus Digestive 1.22 1 – 1.48 0.0463 106 1472 exclusion phecode
530.14 Reflux esophagitis Digestive 1.16 1.04 – 1.3 0.00816 367 4224 exclusion phecode
530.15 Eosinophilic esophagitis Digestive 1.09 0.814 – 1.47 0.554 49 627 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.24 1.04 – 1.48 0.0166 137 1353 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1.15 0.999 – 1.33 0.052 217 2006 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.23 1.03 – 1.47 0.023 131 1344 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.841 0.581 – 1.22 0.36 43 257 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.69 1.1 – 2.58 0.0164 22 185 exclusion phecode
530.9 Heartburn Digestive 1.2 1.07 – 1.36 0.00256 300 3782 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.23 1.12 – 1.36 4.03e-05 435 4455 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.22 0.974 – 1.52 0.084 81 733 exclusion phecode
531.2 Gastric ulcer Digestive 1.29 1.13 – 1.47 0.000129 247 2646 exclusion phecode
531.3 Duodenal ulcer Digestive 1.24 1.01 – 1.52 0.0425 99 883 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.21 1.04 – 1.42 0.0149 180 1724 exclusion phecode
531.5 Gastrojejunal ulcer Digestive 1.14 0.825 – 1.58 0.424 38 323 exclusion phecode
532 Dysphagia Digestive 1.25 1.18 – 1.33 3.31e-13 1388 6859 exclusion phecode
535 Gastritis and duodenitis Digestive 1.05 0.963 – 1.14 0.274 611 6299 exclusion phecode
535.1 Acute gastritis Digestive 1.21 1.06 – 1.38 0.00496 238 2623 exclusion phecode
535.2 Atrophic gastritis Digestive 0.93 0.73 – 1.18 0.555 76 786 exclusion phecode
535.6 Duodenitis Digestive 0.948 0.74 – 1.21 0.675 67 710 exclusion phecode
535.8 Other specified gastritis Digestive 1.02 0.86 – 1.21 0.823 142 1439 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.985 0.873 – 1.11 0.8 294 2905 exclusion phecode
536 Disorders of function of stomach Digestive 1.12 1.04 – 1.21 0.00276 771 6521 exclusion phecode
536.3 Gastroparesis Digestive 1.21 1.04 – 1.42 0.0158 184 1584 exclusion phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.36 1.12 – 1.64 0.00165 137 858 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.11 1.02 – 1.22 0.0216 544 4961 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.15 1.07 – 1.24 0.000348 746 6762 exclusion phecode
537.1 Lesions of stomach and duodenum Digestive 1.42 1.01 – 1.99 0.0418 34 309 exclusion phecode
539 Bariatric surgery Digestive 2.32 1.82 – 2.95 6.13e-12 73 3739 exclusion phecode
540 Appendiceal conditions Digestive 1.01 0.838 – 1.22 0.917 126 1222 exclusion phecode
540.1 Appendicitis Digestive 0.97 0.792 – 1.19 0.769 110 1037 exclusion phecode
540.11 Acute appendicitis Digestive 0.971 0.779 – 1.21 0.791 95 855 exclusion phecode
550 Abdominal hernia Digestive 0.997 0.937 – 1.06 0.931 1207 8816 exclusion phecode
550.1 Inguinal hernia Digestive 0.873 0.788 – 0.966 0.0085 445 3017 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.06 0.962 – 1.17 0.232 446 5737 exclusion phecode
550.3 Femoral hernia Digestive 0.898 0.654 – 1.23 0.507 51 272 exclusion phecode
550.4 Umbilical hernia Digestive 0.888 0.756 – 1.04 0.149 155 2658 exclusion phecode
550.5 Ventral hernia Digestive 1.13 1.01 – 1.26 0.0375 340 4744 exclusion phecode
550.6 Incisional hernia Digestive 1.17 1.01 – 1.36 0.0387 177 2826 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.17 1.06 – 1.3 0.00165 466 3704 exclusion phecode
555.1 Regional enteritis Digestive 1.31 1.16 – 1.48 1.63e-05 313 2269 exclusion phecode
555.2 Ulcerative colitis Digestive 1.04 0.912 – 1.18 0.567 273 2180 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 0.978 0.826 – 1.16 0.791 175 1300 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.14 0.963 – 1.34 0.131 159 1371 exclusion phecode
556.1 Ulceration of intestine Digestive 1.13 0.945 – 1.35 0.181 139 1217 exclusion phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 1.23 0.886 – 1.7 0.219 40 393 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.17 1.05 – 1.3 0.00425 381 4374 exclusion phecode
557.1 Celiac disease Digestive 1.15 0.966 – 1.38 0.115 155 1065 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.13 1.05 – 1.21 0.000839 893 6442 exclusion phecode
559 Ileostomy status Digestive 1.25 1.09 – 1.43 0.00114 248 2053 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.2 1.11 – 1.29 4.55e-06 792 5625 exclusion phecode
560.1 Paralytic ileus Digestive 1.17 1.05 – 1.3 0.00473 385 3274 exclusion phecode
560.2 Impaction of intestine Digestive 1.22 1 – 1.49 0.0497 111 930 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.15 0.914 – 1.44 0.235 90 613 exclusion phecode
560.4 Other intestinal obstruction Digestive 1.25 1.13 – 1.38 9.78e-06 482 3597 exclusion phecode
561 Symptoms involving digestive system Digestive 1.06 0.971 – 1.15 0.205 672 5257 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 0.976 0.908 – 1.05 0.505 1035 4936 exclusion phecode
562.1 Diverticulosis Digestive 0.97 0.902 – 1.04 0.403 1026 4925 exclusion phecode
562.2 Diverticulitis Digestive 1.14 1 – 1.31 0.0487 249 3143 exclusion phecode
564 Functional digestive disorders Digestive 1.09 1.04 – 1.14 0.000216 2747 6964 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.05 0.974 – 1.13 0.212 904 5634 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.14 1.05 – 1.23 0.00172 685 5931 exclusion phecode
565 Anal and rectal conditions Digestive 0.991 0.92 – 1.07 0.818 818 6940 exclusion phecode
565.1 Anal and rectal polyp Digestive 0.871 0.759 – 0.999 0.0478 236 2505 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.33 1.18 – 1.5 1.65e-06 336 2915 exclusion phecode
568 Other disorders of peritoneum Digestive 1.13 1.01 – 1.25 0.0309 372 3676 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.11 0.976 – 1.27 0.111 262 2676 exclusion phecode
569 Other disorders of intestine Digestive 1.09 1.04 – 1.16 0.00104 1700 8326 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.21 0.956 – 1.54 0.112 81 697 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.22 1.08 – 1.37 0.00135 304 3101 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.15 1.06 – 1.25 0.000519 692 7454 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.14 1.05 – 1.24 0.00244 622 7333 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.28 1.1 – 1.5 0.00175 178 1964 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.37 0.981 – 1.92 0.0646 38 370 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.31 1.13 – 1.52 0.000442 201 1842 exclusion phecode
571.81 Portal hypertension Digestive 1.31 1.07 – 1.61 0.00955 106 1127 exclusion phecode
572 Ascites (non malignant) Digestive 1.2 1.1 – 1.31 4.7e-05 575 5073 exclusion phecode
573 Other disorders of liver Digestive 1.11 1.04 – 1.19 0.00215 1049 7805 exclusion phecode
573.1 Chronic passive congestion of liver Digestive 1.67 1.12 – 2.51 0.0123 33 296 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.18 0.922 – 1.5 0.191 71 550 exclusion phecode
573.3 Hepatomegaly Digestive 1.21 0.979 – 1.49 0.0772 93 1082 exclusion phecode
573.4 Acute and subacute necrosis of liver Digestive 1.08 0.852 – 1.38 0.511 80 635 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.16 1.01 – 1.34 0.0321 232 1937 exclusion phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.12 1.03 – 1.23 0.00973 560 5842 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.1 1.01 – 1.2 0.0373 572 6092 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.11 1.04 – 1.19 0.00189 969 7954 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.12 1.02 – 1.23 0.0131 520 7209 exclusion phecode
574.1 Cholelithiasis Digestive 1.1 1 – 1.22 0.0479 455 6806 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.94 0.699 – 1.27 0.685 46 772 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.909 0.72 – 1.15 0.421 77 1290 exclusion phecode
574.2 Calculus of bile duct Digestive 1.03 0.87 – 1.21 0.747 161 1979 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.17 0.976 – 1.39 0.0907 137 1871 exclusion phecode
575 Other biliary tract disease Digestive 1.13 1.03 – 1.25 0.00873 496 5142 exclusion phecode
575.1 Cholangitis Digestive 1.17 0.955 – 1.44 0.127 101 731 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.25 1.07 – 1.46 0.0059 173 1349 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.759 0.555 – 1.04 0.0858 40 529 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.18 1.01 – 1.38 0.0424 170 2192 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.18 1.05 – 1.33 0.00719 302 2508 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.983 0.745 – 1.3 0.905 56 590 exclusion phecode
577 Diseases of pancreas Digestive 1.15 1.05 – 1.25 0.00244 554 4716 exclusion phecode
577.1 Acute pancreatitis Digestive 1.25 1.11 – 1.42 0.000315 285 2551 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.47 1.22 – 1.76 4.63e-05 138 982 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.09 0.916 – 1.29 0.336 158 1167 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.06 0.995 – 1.14 0.0686 1007 8632 exclusion phecode
578.1 Hematemesis Digestive 1.23 1.02 – 1.48 0.0269 117 1060 exclusion phecode
578.2 Blood in stool Digestive 1.07 0.983 – 1.17 0.118 600 5938 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.01 0.917 – 1.11 0.861 476 5034 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.12 1.01 – 1.26 0.0382 349 3224 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.11 1.04 – 1.19 0.00188 975 7967 exclusion phecode
579.2 Splenomegaly Digestive 1.14 0.953 – 1.37 0.15 121 1577 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.08 0.966 – 1.21 0.173 326 3092 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.28 1.14 – 1.44 3.61e-05 327 3423 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.36 1.09 – 1.69 0.00586 93 846 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.33 0.913 – 1.95 0.136 30 314 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.59 0.98 – 2.58 0.0603 17 241 exclusion phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.16 0.713 – 1.87 0.557 13 135 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.49 1.15 – 1.92 0.0022 71 621 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.11 0.812 – 1.51 0.519 37 466 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.32 1.15 – 1.5 6.34e-05 249 2607 exclusion phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.33 1.11 – 1.59 0.0019 138 1500 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.32 1.11 – 1.57 0.00139 147 1449 exclusion phecode
580.4 Renal sclerosis, NOS Genitourinary 1.37 1.07 – 1.76 0.0121 71 754 exclusion phecode
585 Renal failure Genitourinary 1.28 1.2 – 1.36 3.53e-15 1352 7675 exclusion phecode
585.1 Acute renal failure Genitourinary 1.33 1.23 – 1.43 4.1e-13 803 6037 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.26 1.07 – 1.47 0.00406 182 1711 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.26 1.17 – 1.35 1.21e-10 985 6716 exclusion phecode
585.31 Renal dialysis Genitourinary 1.39 1.19 – 1.63 5.49e-05 176 1530 exclusion phecode
585.32 End stage renal disease Genitourinary 1.47 1.28 – 1.69 4.65e-08 238 2054 exclusion phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.26 1.14 – 1.39 3.05e-06 492 4489 exclusion phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.28 1.1 – 1.49 0.0017 187 1901 exclusion phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.26 1.09 – 1.45 0.00139 232 2389 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.12 1.06 – 1.19 6.18e-05 1476 8474 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.2 0.965 – 1.5 0.101 86 891 exclusion phecode
586.11 Small kidney Genitourinary 1.16 0.861 – 1.57 0.328 45 515 exclusion phecode
586.12 Vesicoureteral reflux Genitourinary 1.15 0.847 – 1.56 0.373 40 401 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.02 0.892 – 1.16 0.807 257 2645 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.17 0.857 – 1.61 0.316 44 391 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.05 0.94 – 1.16 0.414 391 3829 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.36 1.18 – 1.56 1.69e-05 231 1742 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.31 1.14 – 1.51 0.00016 220 2000 exclusion phecode
588.1 Renal osteodystrophy Genitourinary 1.29 1.02 – 1.63 0.0343 85 582 exclusion phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.27 1.07 – 1.49 0.00499 155 1556 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.22 1.06 – 1.42 0.00661 210 2132 exclusion phecode
590 Pyelonephritis Genitourinary 1.06 0.948 – 1.2 0.289 326 3559 exclusion phecode
591 Urinary tract infection Genitourinary 1 0.953 – 1.05 0.976 2300 7506 exclusion phecode
592 Cystitis and urethritis Genitourinary 0.997 0.922 – 1.08 0.95 740 5943 exclusion phecode
592.1 Cystitis Genitourinary 1.01 0.934 – 1.1 0.76 698 5747 exclusion phecode
592.11 Acute cystitis Genitourinary 0.99 0.892 – 1.1 0.843 421 4051 exclusion phecode
592.12 Chronic cystitis Genitourinary 1.09 0.806 – 1.47 0.586 49 587 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.06 0.878 – 1.27 0.565 139 1166 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.944 0.726 – 1.23 0.67 62 490 exclusion phecode
593 Hematuria Genitourinary 0.966 0.902 – 1.03 0.324 970 7381 exclusion phecode
593.1 Gross hematuria Genitourinary 0.893 0.79 – 1.01 0.0704 285 2873 exclusion phecode
593.2 Microscopic hematuria Genitourinary 0.923 0.8 – 1.07 0.276 229 2282 exclusion phecode
594 Urinary calculus Genitourinary 1.05 0.99 – 1.12 0.101 1206 9137 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.04 0.981 – 1.11 0.176 1117 9085 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.05 0.835 – 1.32 0.683 80 715 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.01 0.886 – 1.16 0.847 234 3001 exclusion phecode
594.8 Renal colic Genitourinary 1.1 0.861 – 1.41 0.44 70 882 exclusion phecode
595 Hydronephrosis Genitourinary 1.16 1.04 – 1.29 0.00874 382 3817 exclusion phecode
596 Other disorders of bladder Genitourinary 0.958 0.883 – 1.04 0.31 673 5962 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.03 0.817 – 1.31 0.778 75 680 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 0.971 0.871 – 1.08 0.595 381 3817 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.955 0.843 – 1.08 0.472 278 2509 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.855 0.712 – 1.03 0.0922 129 1171 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.01 0.88 – 1.17 0.846 217 2148 exclusion phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.16 0.849 – 1.59 0.352 40 454 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.4 0.918 – 2.13 0.119 25 281 exclusion phecode
598.4 Other cells and casts in urine Genitourinary 1.38 0.878 – 2.15 0.164 23 247 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.964 0.923 – 1.01 0.104 3011 7568 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.761 0.634 – 0.914 0.00352 132 1245 exclusion phecode
599.2 Retention of urine Genitourinary 0.97 0.906 – 1.04 0.389 1038 6664 exclusion phecode
599.3 Dysuria Genitourinary 0.967 0.905 – 1.03 0.331 1049 6736 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.954 0.889 – 1.02 0.192 972 6365 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 0.947 0.886 – 1.01 0.105 1105 6871 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.19 0.995 – 1.42 0.0561 142 1204 exclusion phecode
599.7 Urethral discharge Genitourinary 0.737 0.471 – 1.15 0.18 18 194 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 0.902 0.844 – 0.964 0.00234 1114 6590 exclusion phecode
599.9 Other abnormality of urination Genitourinary 0.879 0.807 – 0.958 0.0032 621 5727 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.891 0.807 – 0.984 0.0231 641 1750 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 0.958 0.815 – 1.13 0.606 157 1631 exclusion phecode
601.1 Prostatitis Genitourinary 0.892 0.702 – 1.13 0.348 76 724 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.922 0.614 – 1.39 0.697 31 199 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1.2 0.658 – 2.19 0.553 12 142 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.972 0.761 – 1.24 0.823 61 681 exclusion phecode
601.4 Balanoposthitis Genitourinary 1.01 0.601 – 1.71 0.956 13 226 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.15 0.78 – 1.69 0.482 23 286 exclusion phecode
602 Other disorders of prostate Genitourinary 1.02 0.786 – 1.33 0.86 67 483 exclusion phecode
602.3 Dysplasia of prostate Genitourinary 1.72 0.874 – 3.4 0.116 15 93 exclusion phecode
603 Other disorders of testis Genitourinary 1.03 0.835 – 1.28 0.764 86 836 exclusion phecode
603.1 Hydrocele Genitourinary 0.982 0.735 – 1.31 0.901 47 521 exclusion phecode
603.2 Spermatocele Genitourinary 0.901 0.662 – 1.23 0.508 40 283 exclusion phecode
604 Disorders of penis Genitourinary 0.977 0.822 – 1.16 0.795 133 1209 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.34 0.85 – 2.11 0.208 16 263 exclusion phecode
604.3 Peyronie's disease Genitourinary 0.838 0.619 – 1.13 0.252 48 330 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.922 0.835 – 1.02 0.106 496 2198 exclusion phecode
608 Other disorders of male genital organs Genitourinary 0.959 0.855 – 1.08 0.474 317 2629 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.981 0.792 – 1.22 0.863 77 860 exclusion phecode
609.1 Infertility, male Genitourinary 1.1 0.856 – 1.41 0.465 56 653 exclusion phecode
609.11 Azoospermia and oligospermia Genitourinary 1.44 0.905 – 2.29 0.124 14 230 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.624 0.421 – 0.926 0.019 24 295 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.871 0.812 – 0.933 9.48e-05 1103 4593 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.876 0.794 – 0.967 0.00828 506 3675 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 0.684 0.41 – 1.14 0.147 19 147 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.856 0.793 – 0.923 6.14e-05 879 4543 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.897 0.803 – 1 0.0566 390 3126 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.872 0.823 – 0.923 2.84e-06 1789 4939 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.838 0.787 – 0.892 3.12e-08 1489 4263 exclusion phecode
611.11 Mammographic microcalcification Genitourinary 0.826 0.735 – 0.928 0.00132 364 2535 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.89 0.831 – 0.954 0.000919 1089 4931 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.845 0.735 – 0.972 0.018 232 2773 exclusion phecode
612.1 Galactorrhea Genitourinary 0.832 0.586 – 1.18 0.305 34 435 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.871 0.728 – 1.04 0.132 135 2033 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 0.665 0.448 – 0.987 0.0428 36 230 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.92 0.861 – 0.983 0.0139 1132 5978 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 0.942 0.796 – 1.11 0.487 152 1564 exclusion phecode
613.5 Mastodynia Genitourinary 0.989 0.897 – 1.09 0.821 489 4210 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.869 0.763 – 0.99 0.0349 269 2329 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 0.858 0.753 – 0.977 0.0205 273 2469 exclusion phecode
613.9 Breast disorder NOS Genitourinary 0.911 0.82 – 1.01 0.0812 424 3595 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.934 0.873 – 1 0.0504 1089 5485 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.956 0.758 – 1.21 0.707 84 897 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.02 0.846 – 1.22 0.865 140 1356 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.05 0.694 – 1.58 0.826 31 282 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.05 0.79 – 1.39 0.744 61 500 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.948 0.741 – 1.21 0.675 72 687 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.937 0.693 – 1.27 0.67 52 476 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.915 0.851 – 0.984 0.0166 944 5450 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.05 0.817 – 1.35 0.702 71 767 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.926 0.857 – 1 0.0486 820 5315 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.993 0.7 – 1.41 0.966 37 368 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.76 0.579 – 0.996 0.047 59 631 exclusion phecode
615 Endometriosis Genitourinary 0.959 0.866 – 1.06 0.43 433 3999 exclusion phecode
618 Genital prolapse Genitourinary 0.96 0.872 – 1.06 0.4 508 4723 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.941 0.839 – 1.06 0.304 345 3445 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.981 0.825 – 1.17 0.824 145 1379 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.913 0.712 – 1.17 0.472 73 757 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.02 0.833 – 1.25 0.843 103 1118 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 0.977 0.922 – 1.04 0.437 1658 5216 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.942 0.839 – 1.06 0.31 344 3480 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 1.01 0.851 – 1.2 0.916 154 1622 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.917 0.774 – 1.09 0.315 163 1311 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.971 0.896 – 1.05 0.465 760 5121 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.988 0.878 – 1.11 0.841 326 3206 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1.08 0.892 – 1.31 0.423 118 1063 exclusion phecode
620.1 Dysplasia of cervix Genitourinary 0.976 0.743 – 1.28 0.865 57 513 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.749 0.578 – 0.97 0.0283 63 1163 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.876 0.782 – 0.981 0.0218 353 3805 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.824 0.722 – 0.941 0.00414 258 2965 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 0.936 0.773 – 1.13 0.501 123 1162 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 0.978 0.848 – 1.13 0.757 220 2246 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.976 0.88 – 1.08 0.637 437 3600 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.893 0.674 – 1.18 0.433 55 525 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 1.06 0.696 – 1.61 0.794 28 159 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.856 0.769 – 0.954 0.00486 388 3990 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.931 0.878 – 0.986 0.0156 1668 4852 exclusion phecode
625.1 Dyspareunia Genitourinary 0.905 0.813 – 1.01 0.0695 405 3480 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.896 0.844 – 0.951 0.000311 1676 4395 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.892 0.834 – 0.955 0.000947 1227 4097 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.935 0.826 – 1.06 0.29 304 2629 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 0.915 0.833 – 1.01 0.064 547 3486 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.883 0.804 – 0.97 0.00964 552 3582 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.903 0.794 – 1.03 0.122 278 2647 exclusion phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.752 0.611 – 0.925 0.00706 108 1134 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.913 0.819 – 1.02 0.0974 408 3005 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.876 0.704 – 1.09 0.235 99 955 exclusion phecode
626.8 Infertility, female Genitourinary 0.838 0.733 – 0.958 0.00976 255 2068 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.866 0.809 – 0.926 2.82e-05 1243 3886 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 0.795 0.698 – 0.905 0.000531 277 2549 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.862 0.797 – 0.933 0.000244 834 3588 exclusion phecode
627.21 Symptomatic artificial menopause Genitourinary 0.781 0.552 – 1.11 0.163 40 402 exclusion phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.79 0.645 – 0.968 0.0232 113 855 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.813 0.718 – 0.919 0.000962 314 2315 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 0.858 0.679 – 1.08 0.2 91 963 exclusion phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.896 0.732 – 1.1 0.289 118 838 exclusion phecode
628 Ovarian cyst Genitourinary 0.882 0.803 – 0.968 0.00846 539 3925 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.12 0.975 – 1.28 0.111 244 2293 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1 0.798 – 1.26 0.971 90 772 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.963 0.662 – 1.4 0.846 30 347 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.918 0.783 – 1.08 0.289 183 1632 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.94 0.775 – 1.14 0.528 122 1112 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.914 0.728 – 1.15 0.439 88 909 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.99 0.882 – 1.11 0.862 351 2386 exclusion phecode
636.1 Threatened premature labor Pregnancy Complications 0.986 0.818 – 1.19 0.883 131 1173 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.975 0.778 – 1.22 0.825 92 869 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.927 0.773 – 1.11 0.41 132 1359 exclusion phecode
636.8 Cervical incompetence Pregnancy Complications 1.07 0.687 – 1.67 0.765 22 245 exclusion phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.48 0.959 – 2.28 0.0765 20 240 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.875 0.728 – 1.05 0.154 129 1768 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.894 0.687 – 1.16 0.405 66 885 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.06 0.829 – 1.36 0.631 71 800 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1 0.71 – 1.42 0.982 35 368 exclusion phecode
644 Anemia during pregnancy Pregnancy Complications 1.25 0.962 – 1.63 0.095 69 747 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.07 0.927 – 1.23 0.363 227 2138 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.05 0.82 – 1.34 0.704 75 655 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.978 0.743 – 1.29 0.872 63 712 exclusion phecode
647.3 Major puerperal infection Pregnancy Complications 1.23 0.751 – 2 0.415 20 204 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.01 0.899 – 1.13 0.882 367 2532 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.937 0.773 – 1.14 0.508 124 1610 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.07 0.903 – 1.26 0.442 163 1713 exclusion phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.06 0.795 – 1.41 0.698 54 637 exclusion phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 0.911 0.703 – 1.18 0.481 65 637 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.951 0.863 – 1.05 0.317 514 3055 exclusion phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 0.893 0.762 – 1.05 0.161 188 1757 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.09 0.949 – 1.24 0.231 253 2170 exclusion phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 0.986 0.476 – 2.04 0.969 5 144 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.972 0.851 – 1.11 0.676 266 2143 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.18 0.899 – 1.54 0.236 64 707 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.959 0.691 – 1.33 0.802 44 543 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.759 0.582 – 0.991 0.0424 63 580 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.17 1.1 – 1.24 1.77e-07 1331 9223 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.1 0.964 – 1.25 0.162 259 2612 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.23 1.07 – 1.41 0.00376 224 2219 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.22 1.1 – 1.36 0.000151 397 4472 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.18 1.07 – 1.31 0.00104 406 4641 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.25 1.11 – 1.4 0.000128 330 3685 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.21 1.07 – 1.37 0.00193 285 3560 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.12 1.02 – 1.24 0.0156 485 4893 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 0.964 0.794 – 1.17 0.708 114 1391 exclusion phecode
686.2 Impetigo Dermatologic 1.17 0.938 – 1.45 0.167 102 1017 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.41 0.966 – 2.05 0.0755 28 403 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.07 0.748 – 1.52 0.718 34 380 exclusion phecode
686.5 Pyoderma Dermatologic 2.05 1.02 – 4.1 0.0437 8 144 exclusion phecode
687 Symptoms affecting skin Dermatologic 0.952 0.86 – 1.05 0.339 449 3752 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.974 0.922 – 1.03 0.349 1623 8190 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.969 0.77 – 1.22 0.792 85 837 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.06 0.997 – 1.12 0.0639 1359 8010 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.923 0.88 – 0.969 0.0013 2241 8716 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.905 0.849 – 0.965 0.00228 1200 6764 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.904 0.848 – 0.964 0.00218 1200 6752 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.958 0.792 – 1.16 0.663 123 1322 exclusion phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 1.43 0.886 – 2.32 0.143 21 163 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.841 0.764 – 0.925 0.000355 500 4084 exclusion phecode
694.1 Vitiligo Dermatologic 1.11 0.792 – 1.57 0.534 37 300 exclusion phecode
694.2 Other dyschromia Dermatologic 0.817 0.738 – 0.903 8.46e-05 447 3711 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.09 0.679 – 1.74 0.73 24 163 exclusion phecode
695 Erythematous conditions Dermatologic 0.995 0.924 – 1.07 0.896 844 6904 exclusion phecode
695.1 Toxic erythema Dermatologic 0.85 0.497 – 1.45 0.551 15 173 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.16 0.694 – 1.93 0.576 20 172 exclusion phecode
695.3 Rosacea Dermatologic 0.848 0.76 – 0.947 0.00353 366 3953 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.18 1.01 – 1.38 0.0375 185 1711 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.16 0.889 – 1.52 0.27 67 616 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.18 1.01 – 1.38 0.0428 177 1613 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 1.07 0.876 – 1.3 0.517 113 1324 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1.04 0.851 – 1.26 0.717 105 1866 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.895 0.546 – 1.47 0.658 15 165 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.06 0.888 – 1.27 0.513 132 1504 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.907 0.799 – 1.03 0.132 275 3123 exclusion phecode
696.3 Pityriasis Dermatologic 0.743 0.509 – 1.09 0.124 36 277 exclusion phecode
696.4 Psoriasis Dermatologic 0.949 0.827 – 1.09 0.457 238 2876 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.952 0.825 – 1.1 0.494 222 2603 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.858 0.625 – 1.18 0.343 41 615 exclusion phecode
697 Sarcoidosis Dermatologic 0.995 0.75 – 1.32 0.974 47 653 exclusion phecode
698 Pruritus and related conditions Dermatologic 0.954 0.872 – 1.04 0.299 557 5421 exclusion phecode
700 Corns and callosities Dermatologic 0.997 0.869 – 1.14 0.97 229 2355 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.953 0.903 – 1.01 0.0762 1735 9024 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 1.03 0.865 – 1.24 0.707 141 1181 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.998 0.916 – 1.09 0.959 623 5144 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.909 0.755 – 1.09 0.312 133 1404 exclusion phecode
701.4 Keloid scar Dermatologic 0.865 0.729 – 1.03 0.0969 158 1531 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1.12 0.899 – 1.39 0.316 91 904 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.873 0.823 – 0.926 5.98e-06 1588 6196 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.833 0.774 – 0.896 9.87e-07 950 5238 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.883 0.829 – 0.94 0.000114 1277 6486 exclusion phecode
702.4 Degenerative skin disorders Dermatologic 1.08 0.71 – 1.65 0.716 25 197 exclusion phecode
703 Diseases of nail, NOS Dermatologic 0.874 0.78 – 0.981 0.0219 333 3307 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.882 0.753 – 1.03 0.12 167 1978 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.944 0.874 – 1.02 0.138 765 7325 exclusion phecode
704.1 Alopecia Dermatologic 0.884 0.796 – 0.982 0.0218 409 3630 exclusion phecode
704.11 Alopecia Areata Dermatologic 1.13 0.717 – 1.79 0.594 21 179 exclusion phecode
704.12 Telogen effluvium Dermatologic 0.888 0.552 – 1.43 0.623 22 160 exclusion phecode
704.2 Hirsutism Dermatologic 1.19 0.887 – 1.59 0.246 45 882 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.01 0.903 – 1.12 0.914 375 3901 exclusion phecode
705 Disorders of sweat glands Dermatologic 0.925 0.764 – 1.12 0.42 115 1541 exclusion phecode
705.1 Dyshidrosis Dermatologic 0.755 0.507 – 1.12 0.165 33 340 exclusion phecode
705.3 Hidradenitis Dermatologic 1.15 0.831 – 1.58 0.403 33 639 exclusion phecode
705.8 Hyperhidrosis Dermatologic 0.982 0.862 – 1.12 0.783 263 2649 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 0.87 0.823 – 0.92 1.03e-06 1531 9248 exclusion phecode
706.1 Acne Dermatologic 0.839 0.779 – 0.904 3.9e-06 832 5978 exclusion phecode
706.2 Sebaceous cyst Dermatologic 0.91 0.837 – 0.99 0.0275 644 6019 exclusion phecode
706.3 Seborrhea Dermatologic 0.725 0.424 – 1.24 0.239 16 137 exclusion phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.848 0.754 – 0.955 0.00643 322 3244 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.22 1.12 – 1.33 7.62e-06 597 5738 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.27 1.1 – 1.48 0.00133 206 1652 exclusion phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.32 1.14 – 1.54 0.00034 180 1928 exclusion phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1.21 1.09 – 1.35 0.000531 356 3547 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.989 0.889 – 1.1 0.839 383 3529 exclusion phecode
709.2 Sicca syndrome Dermatologic 0.949 0.795 – 1.13 0.568 132 1192 exclusion phecode
709.3 Systemic sclerosis Dermatologic 1.05 0.83 – 1.34 0.67 72 515 exclusion phecode
709.5 Dermatomyositis Dermatologic 0.971 0.619 – 1.52 0.896 18 210 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.39 0.906 – 2.13 0.132 27 213 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.02 0.888 – 1.17 0.794 239 2277 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.27 1.12 – 1.44 0.000125 282 2616 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.29 1.14 – 1.46 7.12e-05 275 2462 exclusion phecode
710.11 Acute osteomyelitis Musculoskeletal 1.43 1.19 – 1.71 0.000119 130 1196 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.28 1.07 – 1.54 0.00847 126 1049 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.31 1.15 – 1.49 3.65e-05 258 2362 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 0.803 0.634 – 1.02 0.0697 77 883 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.03 0.76 – 1.39 0.857 46 610 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.07 0.753 – 1.52 0.703 31 400 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.06 0.817 – 1.37 0.664 62 642 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.5 0.947 – 2.38 0.0839 20 304 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.1 0.995 – 1.21 0.064 468 4438 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.14 1.02 – 1.27 0.0172 386 3663 exclusion phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.21 0.857 – 1.7 0.282 33 237 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.13 0.988 – 1.29 0.0742 244 2802 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.12 0.858 – 1.47 0.397 57 676 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.07 0.799 – 1.43 0.661 50 545 exclusion phecode
716 Other arthropathies Musculoskeletal 1.05 1 – 1.1 0.0419 2506 7939 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.753 0.518 – 1.09 0.136 33 432 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.996 0.645 – 1.54 0.985 20 272 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.05 1 – 1.1 0.0402 2492 7936 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.954 0.706 – 1.29 0.757 52 562 exclusion phecode
720 Spinal stenosis Musculoskeletal 1.07 0.981 – 1.16 0.13 649 6151 exclusion phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1.1 0.992 – 1.21 0.0714 428 4881 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1.05 0.987 – 1.13 0.116 1075 7226 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.05 0.982 – 1.12 0.154 1008 7068 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.09 0.92 – 1.29 0.316 152 1737 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 1.1 0.791 – 1.52 0.579 40 562 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.07 1 – 1.13 0.0477 1199 8037 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.07 0.983 – 1.16 0.119 659 7186 exclusion phecode
722.3 Schmorl's nodes Musculoskeletal 1.15 0.797 – 1.66 0.452 32 264 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.08 0.999 – 1.17 0.0542 752 6798 exclusion phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.08 0.862 – 1.35 0.512 92 1084 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.09 0.856 – 1.39 0.486 73 827 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.956 0.856 – 1.07 0.422 370 4256 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.05 0.917 – 1.21 0.458 230 2233 exclusion phecode
723.1 Torticollis Musculoskeletal 0.984 0.759 – 1.28 0.905 62 589 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.04 0.972 – 1.12 0.243 890 7601 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1.03 0.938 – 1.13 0.542 520 5376 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.962 0.779 – 1.19 0.716 98 1021 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.1 0.94 – 1.28 0.244 175 2182 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.07 0.95 – 1.21 0.253 288 3198 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.933 0.887 – 0.981 0.00696 2111 7342 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.937 0.886 – 0.992 0.0239 1605 7313 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.929 0.794 – 1.09 0.357 173 2098 exclusion phecode
726.3 Bursitis Musculoskeletal 0.847 0.759 – 0.947 0.00342 359 3818 exclusion phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.867 0.756 – 0.995 0.042 228 2653 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.95 0.898 – 1 0.0741 1618 7309 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.95 0.876 – 1.03 0.222 681 6062 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.942 0.747 – 1.19 0.613 80 907 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.94 0.839 – 1.05 0.28 347 3217 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.998 0.801 – 1.24 0.989 89 1092 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.931 0.841 – 1.03 0.17 420 4585 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.06 0.898 – 1.24 0.505 167 1482 exclusion phecode
727.8 Plica syndrome Musculoskeletal 0.948 0.696 – 1.29 0.738 50 385 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.958 0.895 – 1.03 0.216 988 7020 exclusion phecode
728.1 Muscular calcification and ossification Musculoskeletal 1.12 0.745 – 1.69 0.58 22 186 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.06 0.85 – 1.32 0.605 77 712 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.83 0.755 – 0.914 0.000139 473 5331 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.668 0.542 – 0.822 0.000144 108 781 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.09 1.01 – 1.19 0.0303 669 6222 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.79 1.08 – 2.97 0.025 19 168 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.972 0.543 – 1.74 0.924 9 304 exclusion phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 1.15 0.704 – 1.87 0.581 21 155 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.66 1.16 – 2.39 0.00603 36 353 exclusion phecode
732 Osteochondropathies Musculoskeletal 1.06 0.844 – 1.33 0.623 91 1000 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.1 0.783 – 1.55 0.579 40 530 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.28 0.823 – 1.98 0.276 24 265 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.944 0.885 – 1.01 0.0811 1259 6039 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.08 0.802 – 1.44 0.628 53 452 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.26 1.06 – 1.5 0.00746 160 1061 exclusion phecode
733.6 Costochondritis Musculoskeletal 0.834 0.659 – 1.05 0.129 79 878 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.2 1.04 – 1.38 0.014 207 1900 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.06 0.724 – 1.54 0.778 33 261 exclusion phecode
735 Acquired foot deformities Musculoskeletal 0.956 0.885 – 1.03 0.256 762 6663 exclusion phecode
735.1 Flat foot Musculoskeletal 0.872 0.712 – 1.07 0.186 109 1399 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 0.985 0.866 – 1.12 0.813 279 2535 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.15 0.972 – 1.37 0.103 160 1562 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.916 0.739 – 1.13 0.421 103 848 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.865 0.772 – 0.97 0.0129 348 3312 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 0.964 0.885 – 1.05 0.404 614 6048 exclusion phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.976 0.677 – 1.41 0.896 32 220 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.1 0.839 – 1.43 0.502 66 463 exclusion phecode
736.3 Acquired deformities of hip Musculoskeletal 0.904 0.519 – 1.57 0.721 16 188 exclusion phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.991 0.738 – 1.33 0.949 48 682 exclusion phecode
736.5 Acquired deformities of knee Musculoskeletal 0.91 0.645 – 1.28 0.59 32 499 exclusion phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.941 0.745 – 1.19 0.613 78 779 exclusion phecode
737 Curvature of spine Musculoskeletal 1.03 0.929 – 1.13 0.622 462 3890 exclusion phecode
737.1 Kyphosis (acquired) Musculoskeletal 1.11 0.905 – 1.35 0.326 110 1080 exclusion phecode
737.2 Lordosis (acquired) Musculoskeletal 2.08 1.09 – 3.95 0.0257 12 152 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.99 0.888 – 1.1 0.852 386 3060 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.14 1.04 – 1.24 0.00317 631 5535 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.14 0.984 – 1.33 0.0804 198 2157 exclusion phecode
739 Contracture of joint Musculoskeletal 1.03 0.874 – 1.22 0.71 160 1370 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.03 0.986 – 1.08 0.17 2937 7929 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.958 0.897 – 1.02 0.209 1157 6673 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.939 0.875 – 1.01 0.0798 1023 6187 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.07 0.89 – 1.29 0.466 122 1668 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.02 0.902 – 1.16 0.744 306 2887 exclusion phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 1.11 0.87 – 1.42 0.396 71 857 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.04 0.99 – 1.09 0.119 2783 7867 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.01 0.956 – 1.06 0.814 1879 8544 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.815 0.616 – 1.08 0.151 54 599 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 0.986 0.878 – 1.11 0.813 323 2891 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 1.1 1 – 1.21 0.039 496 4936 exclusion phecode
741.4 Joint effusions Musculoskeletal 0.941 0.86 – 1.03 0.18 540 5845 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.08 0.692 – 1.7 0.725 18 199 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.938 0.486 – 1.81 0.849 11 169 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.01 0.945 – 1.08 0.777 1043 8142 exclusion phecode
742.1 Loose body in joint Musculoskeletal 0.944 0.662 – 1.35 0.753 28 422 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.876 0.704 – 1.09 0.236 85 933 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.23 0.948 – 1.6 0.119 62 634 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 1.01 0.942 – 1.08 0.819 985 8034 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.999 0.951 – 1.05 0.964 2537 8248 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.03 0.958 – 1.1 0.457 1230 3995 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.02 0.953 – 1.1 0.533 1217 3952 exclusion phecode
743.12 Senile osteoporosis Musculoskeletal 0.932 0.813 – 1.07 0.306 292 1134 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1.2 0.966 – 1.5 0.0987 109 601 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.08 0.961 – 1.23 0.189 326 2028 exclusion phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 1.14 0.943 – 1.37 0.179 131 862 exclusion phecode
743.22 Pathologic fracture of femur Musculoskeletal 1.54 1.09 – 2.16 0.0143 43 267 exclusion phecode
743.4 Stress fracture Musculoskeletal 0.842 0.689 – 1.03 0.0925 120 924 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.98 0.928 – 1.03 0.464 1853 7744 exclusion phecode
745 Pain in joint Musculoskeletal 0.962 0.926 – 1 0.0536 4517 6498 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.05 0.957 – 1.15 0.308 525 4965 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.11 1 – 1.23 0.0502 389 3920 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.97 0.828 – 1.14 0.707 170 1512 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.16 0.963 – 1.4 0.118 128 1550 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.19 0.958 – 1.47 0.118 88 884 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.954 0.802 – 1.13 0.591 140 1163 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.24 0.852 – 1.81 0.258 29 272 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.904 0.778 – 1.05 0.186 206 1544 exclusion phecode
749.1 Cleft palate Congenital Anomalies 0.889 0.649 – 1.22 0.464 43 310 exclusion phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.972 0.712 – 1.33 0.858 46 303 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 1.08 0.95 – 1.24 0.232 261 2050 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.889 0.712 – 1.11 0.298 88 858 exclusion phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.707 0.474 – 1.05 0.0888 29 248 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.924 0.617 – 1.38 0.701 24 258 exclusion phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 0.854 0.617 – 1.18 0.344 39 269 exclusion phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 1.15 0.564 – 2.36 0.695 11 122 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.12 0.96 – 1.32 0.146 176 1251 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.19 0.979 – 1.45 0.081 110 720 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.07 0.816 – 1.41 0.623 69 509 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.01 0.918 – 1.1 0.887 518 4659 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.06 0.895 – 1.25 0.514 161 1548 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.15 0.944 – 1.4 0.167 116 1100 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.861 0.613 – 1.21 0.39 38 353 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.933 0.831 – 1.05 0.232 332 3026 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.896 0.779 – 1.03 0.121 227 2060 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.922 0.729 – 1.17 0.498 74 675 exclusion phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.39 1.06 – 1.81 0.0177 62 532 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.991 0.862 – 1.14 0.901 227 2647 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.08 0.921 – 1.26 0.35 177 2072 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.817 0.607 – 1.1 0.182 42 500 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.746 0.563 – 0.99 0.0426 58 599 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.15 0.859 – 1.54 0.35 52 476 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.866 0.527 – 1.42 0.57 14 150 exclusion phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 0.898 0.531 – 1.52 0.687 14 144 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.1 0.962 – 1.26 0.164 247 2582 exclusion phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 0.722 0.476 – 1.1 0.126 27 305 exclusion phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 1.14 0.931 – 1.39 0.208 109 1222 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.05 0.895 – 1.23 0.547 175 1999 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.93 0.74 – 1.17 0.533 78 912 exclusion phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 1.12 0.686 – 1.82 0.659 18 180 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.15 0.906 – 1.46 0.25 84 961 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.07 0.792 – 1.46 0.644 50 565 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.987 0.883 – 1.1 0.816 354 3352 exclusion phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.627 0.39 – 1.01 0.0532 21 172 exclusion phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 1.19 0.861 – 1.65 0.291 49 237 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.814 0.629 – 1.05 0.116 62 840 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.01 0.885 – 1.16 0.843 229 2290 exclusion phecode
757 Congenital anomalies of the integument Congenital Anomalies 0.944 0.767 – 1.16 0.59 103 926 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.03 0.766 – 1.38 0.859 58 491 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.961 0.674 – 1.37 0.826 38 363 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.01 0.86 – 1.19 0.889 160 1493 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.915 0.557 – 1.5 0.724 14 188 exclusion phecode
760 Back pain Symptoms 1.09 1.04 – 1.13 8.01e-05 3440 7569 exclusion phecode
761 Cervicalgia Symptoms 1.03 0.975 – 1.09 0.296 1576 9228 exclusion phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 1.03 0.953 – 1.12 0.42 662 7263 exclusion phecode
764 Sciatica Symptoms 1.07 0.983 – 1.16 0.119 611 7266 exclusion phecode
765 Cervical radiculitis Symptoms 1.03 0.929 – 1.15 0.536 371 3862 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.09 1.01 – 1.16 0.0169 1017 8661 exclusion phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.07 0.715 – 1.6 0.74 28 264 exclusion phecode
769 Nonallopathic lesions NEC Symptoms 1.04 0.916 – 1.18 0.544 292 2634 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.04 0.974 – 1.1 0.268 1254 8242 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.09 1.02 – 1.17 0.00954 1015 8355 exclusion phecode
771.1 Swelling of limb Symptoms 1.09 1.02 – 1.17 0.00824 1061 8316 exclusion phecode
771.2 Cramp of limb Symptoms 1.04 0.91 – 1.19 0.546 233 2375 exclusion phecode
772 Symptoms of the muscles Symptoms 0.96 0.874 – 1.05 0.388 507 4726 exclusion phecode
772.1 Muscular wasting and disuse atrophy Symptoms 1.1 0.908 – 1.34 0.326 123 1091 exclusion phecode
772.2 Spasm of muscle Symptoms 0.961 0.878 – 1.05 0.387 542 5508 exclusion phecode
772.3 Muscle weakness Symptoms 1.05 0.968 – 1.14 0.235 640 6137 exclusion phecode
772.4 Rhabdomyolysis Symptoms 1.39 0.977 – 1.98 0.067 38 338 exclusion phecode
772.6 Facial weakness Symptoms 1 0.813 – 1.24 0.968 96 1027 exclusion phecode
780 Hypothermia/Chills Symptoms 0.993 0.811 – 1.22 0.95 104 987 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.985 0.902 – 1.08 0.732 574 5709 exclusion phecode
781.1 Loss of height Symptoms 1.24 0.857 – 1.78 0.257 35 214 exclusion phecode
781.2 Abnormal posture Symptoms 0.949 0.56 – 1.61 0.844 14 123 exclusion phecode
782.3 Edema Symptoms 1.2 1.12 – 1.29 9.59e-08 976 8470 exclusion phecode
782.6 Pallor and flushing Symptoms 0.881 0.769 – 1.01 0.0686 245 2410 exclusion phecode
783 Fever of unknown origin Symptoms 1.13 1.07 – 1.2 2.24e-05 1350 9562 exclusion phecode
783.1 Postprocedural fever Symptoms 1.21 0.924 – 1.59 0.166 58 642 exclusion phecode
785 Abdominal pain Symptoms 1.06 1.02 – 1.1 0.00447 3950 7061 exclusion phecode
788 Syncope and collapse Symptoms 1.04 0.97 – 1.12 0.269 887 8223 exclusion phecode
789 Nausea and vomiting Symptoms 1.07 1.02 – 1.12 0.00449 2685 8302 exclusion phecode
789.1 Persistent vomiting Symptoms 1.24 1.07 – 1.43 0.00341 203 1910 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.12 1.02 – 1.23 0.021 499 4987 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.14 0.841 – 1.54 0.406 42 564 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.1 1.04 – 1.17 0.000849 1441 9098 exclusion phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.13 0.836 – 1.52 0.43 46 771 exclusion phecode
790.9 Abnormal arterial blood gases Symptoms 1.23 0.841 – 1.8 0.287 27 339 exclusion phecode
791 Gangrene Symptoms 1.31 1.04 – 1.65 0.0237 77 589 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 0.972 0.902 – 1.05 0.457 885 4183 exclusion phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 1.01 0.901 – 1.12 0.917 370 2793 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.915 0.738 – 1.13 0.418 96 1118 exclusion phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 1.04 0.952 – 1.13 0.406 639 5303 exclusion phecode
795.8 Abnormal tumor markers Symptoms 0.899 0.795 – 1.02 0.089 295 2567 exclusion phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 1.02 0.524 – 2 0.945 11 129 exclusion phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 1 0.757 – 1.33 0.977 59 490 exclusion phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.804 0.707 – 0.914 0.000841 314 1514 exclusion phecode
797 Shock Symptoms 1.14 0.938 – 1.38 0.189 129 1151 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.22 0.916 – 1.64 0.171 54 436 exclusion phecode
798 Malaise and fatigue Symptoms 1.06 1.01 – 1.11 0.0119 2655 8349 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1.05 0.942 – 1.17 0.39 383 4177 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.04 0.95 – 1.13 0.421 595 5364 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.13 0.949 – 1.34 0.173 151 1086 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.1 0.952 – 1.28 0.189 192 1460 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.05 0.911 – 1.21 0.496 221 2131 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.942 0.769 – 1.16 0.568 105 871 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.02 0.928 – 1.11 0.741 536 5414 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.05 0.921 – 1.19 0.474 249 2719 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.11 0.919 – 1.35 0.273 123 885 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.99 0.909 – 1.08 0.816 608 4860 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1.18 1.01 – 1.37 0.0421 177 1770 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.931 0.833 – 1.04 0.21 360 2789 exclusion phecode
803.21 Colles' fracture Injuries & Poisonings 0.936 0.755 – 1.16 0.543 93 688 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.03 0.879 – 1.2 0.728 176 1228 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.959 0.873 – 1.05 0.389 491 3985 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.05 0.937 – 1.17 0.408 347 2856 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.19 1.02 – 1.39 0.0252 177 1371 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.02 0.949 – 1.1 0.572 829 6736 exclusion phecode
816 Cerebral laceration and contusion Injuries & Poisonings 1.37 0.799 – 2.37 0.251 16 101 exclusion phecode
817 Concussion Injuries & Poisonings 1.03 0.903 – 1.17 0.678 258 2679 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.24 0.999 – 1.55 0.0515 85 688 exclusion phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 1.49 0.953 – 2.33 0.0803 24 189 exclusion phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.31 0.825 – 2.08 0.253 24 203 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.04 0.957 – 1.13 0.343 607 5516 exclusion phecode
830 Dislocation Injuries & Poisonings 0.918 0.855 – 0.987 0.02 868 8371 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.91 0.826 – 1 0.0557 465 5322 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 1.01 0.804 – 1.28 0.906 80 1028 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.909 0.863 – 0.958 0.000356 1782 9030 exclusion phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.947 0.757 – 1.18 0.632 82 1115 exclusion phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.921 0.808 – 1.05 0.218 253 3256 exclusion phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.847 0.783 – 0.916 3.06e-05 746 6296 exclusion phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.971 0.866 – 1.09 0.616 339 3848 exclusion phecode
842 Other sprains and strains Injuries & Poisonings 0.924 0.826 – 1.03 0.171 334 3490 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.14 1.04 – 1.26 0.00693 461 4470 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.24 1.14 – 1.34 1.55e-07 669 5863 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.6 1.3 – 1.96 7.22e-06 107 959 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.26 1.13 – 1.39 1.35e-05 412 4147 exclusion phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.12 0.844 – 1.47 0.444 54 619 exclusion phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.21 0.911 – 1.6 0.191 59 578 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.1 0.971 – 1.26 0.131 269 3092 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.15 1.05 – 1.27 0.00258 517 5130 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.19 1.09 – 1.3 9.54e-05 567 4779 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.34 0.949 – 1.88 0.0967 40 366 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.08 1.01 – 1.15 0.0277 997 8403 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.23 0.923 – 1.64 0.159 55 444 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1.02 0.75 – 1.38 0.912 41 324 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.999 0.898 – 1.11 0.978 392 3010 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.08 0.832 – 1.41 0.557 60 476 exclusion phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 1.14 0.91 – 1.43 0.254 93 604 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 1.16 0.884 – 1.52 0.286 64 395 exclusion phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.12 0.806 – 1.55 0.502 38 391 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.09 1.01 – 1.17 0.0211 808 7420 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.99 0.825 – 1.19 0.915 128 1282 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.924 0.806 – 1.06 0.258 233 2284 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.42 1.13 – 1.77 0.00222 85 951 exclusion phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.34 0.977 – 1.83 0.07 44 583 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.2 0.995 – 1.45 0.0571 109 1075 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.52 1.08 – 2.12 0.0157 34 304 exclusion phecode
875 Non-healing surgical wound Injuries & Poisonings 1.23 1.02 – 1.47 0.027 127 1275 exclusion phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.16 0.986 – 1.37 0.0734 148 1736 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.08 0.947 – 1.24 0.242 237 2291 exclusion phecode
910 Superficial injury, infected Injuries & Poisonings 1.12 0.706 – 1.77 0.638 22 268 exclusion phecode
911 Blister Injuries & Poisonings 1.09 0.829 – 1.44 0.533 50 571 exclusion phecode
912 Insect bite Injuries & Poisonings 0.917 0.756 – 1.11 0.382 112 1187 exclusion phecode
913 Toxic effect of venom Injuries & Poisonings 0.768 0.618 – 0.954 0.017 85 744 exclusion phecode
916 Contusion Injuries & Poisonings 1.04 0.969 – 1.11 0.293 987 8993 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 1.08 0.923 – 1.26 0.337 184 2047 exclusion phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.9 0.755 – 1.07 0.238 149 1629 exclusion phecode
938 Dermatitis due to solar radiation Dermatologic 0.879 0.826 – 0.935 4.69e-05 1328 6321 exclusion phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.955 0.705 – 1.29 0.767 48 508 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.87 0.816 – 0.927 1.65e-05 1269 6176 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.955 0.901 – 1.01 0.12 1492 7699 exclusion phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 1.29 0.854 – 1.94 0.228 28 224 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.959 0.689 – 1.34 0.804 37 380 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.39 1.07 – 1.8 0.0134 76 617 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.923 0.765 – 1.11 0.406 125 1147 exclusion phecode
947 Urticaria Dermatologic 0.951 0.839 – 1.08 0.427 287 2944 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.03 0.975 – 1.09 0.293 1617 7675 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.08 0.885 – 1.31 0.453 107 1049 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.624 0.426 – 0.914 0.0155 34 324 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.07 0.948 – 1.2 0.281 305 2721 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 0.856 0.595 – 1.23 0.401 38 329 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.974 0.663 – 1.43 0.894 34 249 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.19 1.09 – 1.31 0.000139 552 5167 exclusion phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 0.938 0.745 – 1.18 0.583 88 767 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.21 1.08 – 1.36 0.000768 342 3712 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.23 1.03 – 1.47 0.0246 138 1185 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.12 0.978 – 1.29 0.1 233 2385 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.15 0.977 – 1.34 0.0944 172 1659 exclusion phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.12 0.901 – 1.41 0.3 84 794 exclusion phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 2.26 1.09 – 4.68 0.0284 11 118 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.11 0.897 – 1.37 0.339 99 974 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.14 1.05 – 1.24 0.00179 662 5444 exclusion phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.16 1.06 – 1.26 0.00065 644 5337 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.21 1.01 – 1.45 0.0427 129 1472 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.21 0.998 – 1.46 0.0524 120 1391 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.1 0.948 – 1.28 0.206 199 2115 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.31 1.17 – 1.48 7.78e-06 303 3397 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.895 0.594 – 1.35 0.595 27 247 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.26 0.856 – 1.84 0.244 28 229 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.12 0.996 – 1.27 0.0586 305 2905 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.51 1.17 – 1.94 0.00135 74 697 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.39 0.83 – 2.33 0.21 18 124 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.47 1.1 – 1.96 0.00827 51 576 exclusion phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 1.36 0.844 – 2.18 0.207 13 157 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.83 1.1 – 3.03 0.0191 16 198 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.31 0.83 – 2.05 0.248 21 234 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.9 0.523 – 1.55 0.704 14 199 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.868 0.516 – 1.46 0.595 15 160 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.14 1.03 – 1.27 0.0153 383 3849 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.15 1.07 – 1.24 0.000259 797 7171 exclusion phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 1.09 0.963 – 1.23 0.175 288 2809 exclusion phecode
985 Toxic effect of other metals Injuries & Poisonings 1.89 1.03 – 3.45 0.0387 17 92 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.3 0.925 – 1.84 0.129 34 302 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.09 1.02 – 1.17 0.0108 954 6503 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.26 1.14 – 1.39 4.39e-06 461 4485 exclusion phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.29 0.996 – 1.68 0.0538 74 650 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.24 1.12 – 1.37 3.46e-05 429 4266 exclusion phecode
994.21 Septic shock Injuries & Poisonings 1.29 1.08 – 1.55 0.00569 138 1270 exclusion phecode
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