Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Body mass index Michigan Genomics Initiative Freeze 3 (MGI) PheWAS analysis

Body mass index — Michigan Genomics Initiative Freeze 3 (MGI) PRS PheWAS

PRS model
PRS ID exprsweb-bmi-23104-raw-plink-mgi-freeze3-20211120Legacy PLINKC+T (GT)UK Biobank GWAS

Evaluation cohort: Michigan Genomics Initiative Freeze 3 (MGI).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: normal-range subset (18.5-24.9).

For this ExPRS, the exclusion sensitivity scan keeps only the study's normal-range subset for Body mass index (18.5-24.9) before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.

674 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.03 0.986 – 1.07 0.215 3004 29292 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.11 1.05 – 1.18 0.000664 1322 13162 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.1 1.03 – 1.18 0.00491 1046 10455 all phecode
008.6 Viral Enteritis Infectious Diseases 1.09 1 – 1.17 0.0383 770 7676 all phecode
010 Tuberculosis Infectious Diseases 1.03 0.899 – 1.19 0.64 244 2425 all phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.977 0.781 – 1.22 0.843 86 855 all phecode
038 Septicemia Infectious Diseases 1.1 1.06 – 1.15 9.31e-06 2582 24779 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.12 1.02 – 1.22 0.0158 568 5629 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.21 1.05 – 1.39 0.00827 235 2350 all phecode
038.3 Bacteremia Infectious Diseases 1.13 1.06 – 1.2 0.000119 1210 12079 all phecode
041 Bacterial infection NOS Infectious Diseases 1.08 1.05 – 1.11 3.93e-07 5750 38799 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.15 1.09 – 1.21 8.49e-08 1707 16977 all phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.2 1.12 – 1.28 4.9e-07 920 9192 all phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.18 1.09 – 1.28 1.92e-05 783 7812 all phecode
041.2 Streptococcus infection Infectious Diseases 1.09 1.04 – 1.15 0.000974 1632 16287 all phecode
041.21 Rheumatic fever / chorea Infectious Diseases 0.978 0.856 – 1.12 0.738 257 2554 all phecode
041.4 E. coli Infectious Diseases 1.09 1.03 – 1.16 0.00632 1175 11680 all phecode
041.8 H. pylori Infectious Diseases 1.1 0.958 – 1.26 0.18 257 2521 all phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.13 1.01 – 1.26 0.0275 387 3864 all phecode
053 Herpes zoster Infectious Diseases 0.937 0.887 – 0.99 0.0202 1560 15184 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.905 0.782 – 1.05 0.185 220 2169 all phecode
054 Herpes simplex Infectious Diseases 0.947 0.897 – 1 0.0506 1593 15600 all phecode
070 Viral hepatitis Infectious Diseases 1.09 1.01 – 1.17 0.0347 829 8280 all phecode
070.1 Viral hepatitis A Infectious Diseases 1.16 0.909 – 1.47 0.239 87 860 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.15 0.99 – 1.34 0.0676 215 2138 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.07 0.978 – 1.18 0.134 528 5280 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.11 0.944 – 1.3 0.212 197 1964 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.02 0.954 – 1.08 0.614 1145 11381 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.15 0.976 – 1.37 0.0938 145 1450 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.16 0.961 – 1.39 0.124 117 1163 all phecode
078 Viral warts & HPV Infectious Diseases 0.91 0.876 – 0.944 5.73e-07 3434 29624 all phecode
079 Viral infection Infectious Diseases 0.951 0.925 – 0.978 4e-04 6664 35342 all phecode
079.1 Varicella infection Infectious Diseases 0.904 0.872 – 0.936 2.5e-08 3793 31251 all phecode
079.2 Infectious mononucleosis Infectious Diseases 0.871 0.766 – 0.989 0.0334 283 2723 all phecode
079.9 Viremia, NOS Infectious Diseases 1.07 0.994 – 1.16 0.0697 838 8253 all phecode
080 Postoperative infection Infectious Diseases 1.14 1.09 – 1.18 3.3e-09 2619 26065 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.12 1.06 – 1.18 4.89e-05 1589 15884 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.04 0.969 – 1.11 0.293 965 9630 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.02 0.984 – 1.06 0.262 3544 30054 all phecode
110.1 Dermatophytosis Infectious Diseases 1.03 0.988 – 1.07 0.17 3241 27244 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.04 0.992 – 1.09 0.102 2044 16765 all phecode
110.12 Althete's foot Infectious Diseases 1.05 0.978 – 1.13 0.171 899 8043 all phecode
110.13 Dermatophytosis of the body Infectious Diseases 1.07 0.993 – 1.16 0.0742 790 7827 all phecode
110.2 Dermatomycoses Infectious Diseases 0.976 0.877 – 1.09 0.651 398 3971 all phecode
112 Candidiasis Infectious Diseases 1.09 1.05 – 1.13 4.39e-06 3685 30495 all phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.25 1.15 – 1.35 2.52e-07 682 6732 all phecode
117 Mycoses Infectious Diseases 1.02 0.933 – 1.11 0.702 608 6069 all phecode
117.1 Histoplasmosis Infectious Diseases 1.21 0.96 – 1.54 0.105 81 801 all phecode
117.4 Aspergillosis Infectious Diseases 1.07 0.893 – 1.28 0.473 140 1387 all phecode
130 Spirochetal infection Infectious Diseases 0.918 0.781 – 1.08 0.299 168 1677 all phecode
130.1 Lyme disease Infectious Diseases 0.905 0.747 – 1.1 0.309 116 1160 all phecode
131 Protozoan infection Infectious Diseases 1.36 1.05 – 1.75 0.0206 61 610 all phecode
132 Infestation (lice, mites) Infectious Diseases 1.06 0.911 – 1.23 0.465 195 1948 all phecode
134 Helminthiases Infectious Diseases 0.985 0.782 – 1.24 0.896 83 812 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.13 0.844 – 1.52 0.407 53 513 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.05 1.01 – 1.09 0.0114 3279 32486 all phecode
145 Cancer of mouth Neoplasms 1.03 0.979 – 1.09 0.229 1481 14725 all phecode
145.1 Cancer of lip Neoplasms 1.15 0.898 – 1.46 0.275 76 750 all phecode
145.2 Cancer of tongue Neoplasms 1.02 0.94 – 1.11 0.592 645 6430 all phecode
145.3 Cancer of major salivary glands Neoplasms 0.98 0.876 – 1.1 0.732 361 3597 all phecode
145.4 Cancer of the gums Neoplasms 1.04 0.872 – 1.23 0.69 166 1632 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.05 0.907 – 1.23 0.49 206 2048 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.02 0.96 – 1.08 0.535 1290 12873 all phecode
149.1 Cancer of oropharynx Neoplasms 1.03 0.919 – 1.15 0.606 350 3499 all phecode
149.2 Cancer of nasopharynx Neoplasms 1.08 0.877 – 1.33 0.467 100 1000 all phecode
149.3 Cancer of hypopharynx Neoplasms 1.01 0.789 – 1.29 0.94 82 819 all phecode
149.4 Cancer of larynx Neoplasms 1.11 1 – 1.24 0.0503 386 3857 all phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 1.03 0.938 – 1.12 0.574 552 5505 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.918 0.799 – 1.05 0.225 240 2398 all phecode
150 Cancer of esophagus Neoplasms 1.23 1.11 – 1.36 6.3e-05 433 4315 all phecode
151 Cancer of stomach Neoplasms 1.09 0.995 – 1.2 0.0638 498 4962 all phecode
153 Colorectal cancer Neoplasms 0.99 0.935 – 1.05 0.73 1458 14383 all phecode
153.2 Colon cancer Neoplasms 1 0.938 – 1.07 0.996 1160 11472 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.968 0.897 – 1.05 0.408 815 8093 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.06 0.963 – 1.17 0.234 511 5097 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.09 0.97 – 1.22 0.149 344 3433 all phecode
157 Pancreatic cancer Neoplasms 0.984 0.893 – 1.08 0.741 503 5005 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1 0.95 – 1.06 0.914 1623 15759 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.02 0.974 – 1.08 0.351 1818 17869 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.02 0.885 – 1.18 0.754 221 2206 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.02 0.862 – 1.21 0.812 158 1578 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.02 0.901 – 1.16 0.717 293 2920 all phecode
164 Cancer of intrathoracic organs Neoplasms 0.952 0.792 – 1.15 0.605 133 1324 all phecode
165 Cancer within the respiratory system Neoplasms 1.05 0.986 – 1.11 0.138 1336 13340 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.03 0.964 – 1.1 0.375 1057 10552 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.973 0.925 – 1.02 0.293 1792 17850 all phecode
170.1 Bone cancer Neoplasms 0.958 0.886 – 1.04 0.279 773 7690 all phecode
170.2 Cancer of connective tissue Neoplasms 0.97 0.914 – 1.03 0.327 1266 12632 all phecode
172 Skin cancer Neoplasms 0.941 0.916 – 0.965 3.86e-06 8608 33186 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.919 0.89 – 0.948 1.12e-07 5330 30106 all phecode
172.11 Melanomas of skin Neoplasms 0.92 0.884 – 0.957 3.28e-05 3100 25064 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.94 0.914 – 0.967 1.75e-05 7095 30462 all phecode
172.21 Basal cell carcinoma Neoplasms 0.907 0.874 – 0.942 2.76e-07 3690 23868 all phecode
172.22 Squamous cell carcinoma Neoplasms 0.971 0.928 – 1.02 0.195 2414 17683 all phecode
172.3 Carcinoma in situ of skin Neoplasms 0.883 0.834 – 0.934 1.73e-05 1482 12326 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.912 0.869 – 0.958 0.000218 1997 18755 all phecode
174 Breast cancer Neoplasms 0.92 0.883 – 0.958 6.75e-05 3186 15514 all phecode
174.1 Breast cancer [female] Neoplasms 0.918 0.88 – 0.958 7.03e-05 3036 14701 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.92 0.882 – 0.96 0.00011 2991 14639 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.795 0.688 – 0.919 0.00187 233 2307 all phecode
175 Acquired absence of breast Neoplasms 0.954 0.887 – 1.03 0.205 919 8920 all phecode
180 Cervical cancer and dysplasia Neoplasms 1.01 0.956 – 1.07 0.68 1431 12185 all phecode
180.1 Cervical cancer Neoplasms 1.08 0.984 – 1.19 0.102 500 4982 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.969 0.907 – 1.04 0.358 1048 9323 all phecode
182 Malignant neoplasm of uterus Neoplasms 1.14 1.05 – 1.23 0.00168 765 7613 all phecode
184 Cancer of other female genital organs Neoplasms 1 0.941 – 1.07 0.925 1191 11592 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.987 0.9 – 1.08 0.779 573 5719 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.946 0.852 – 1.05 0.301 432 4309 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.05 0.965 – 1.15 0.24 608 6057 all phecode
185 Cancer of prostate Neoplasms 0.937 0.896 – 0.981 0.00489 2901 10342 all phecode
187 Cancer of other male genital organs Neoplasms 0.982 0.874 – 1.1 0.764 339 3384 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.12 0.913 – 1.38 0.276 115 1141 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.971 0.829 – 1.14 0.713 183 1830 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.89 0.668 – 1.19 0.424 57 562 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.1 1.05 – 1.14 9.59e-06 2923 23541 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.11 1.05 – 1.18 0.000183 1450 14437 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.13 1.06 – 1.2 9.32e-05 1267 12655 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.09 0.948 – 1.26 0.221 237 2347 all phecode
189.2 Cancer of bladder Neoplasms 1.09 1.04 – 1.15 0.00108 1783 15224 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.08 1.03 – 1.14 0.00399 1657 14178 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.05 0.963 – 1.14 0.284 678 6586 all phecode
190 Cancer of eye Neoplasms 0.92 0.766 – 1.1 0.37 138 1374 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.987 0.925 – 1.05 0.689 1078 10771 all phecode
191.1 Cancer of brain and nervous system Neoplasms 0.96 0.886 – 1.04 0.32 706 7052 all phecode
191.11 Cancer of brain Neoplasms 0.932 0.855 – 1.02 0.108 600 5996 all phecode
193 Thyroid cancer Neoplasms 1.01 0.942 – 1.08 0.779 945 9393 all phecode
194 Cancer of other endocrine glands Neoplasms 1.03 0.947 – 1.13 0.456 579 5759 all phecode
195 Cancer, suspected or other Neoplasms 1 0.979 – 1.02 0.933 16962 26401 all phecode
195.1 Malignant neoplasm, other Neoplasms 0.997 0.976 – 1.02 0.82 16670 26384 all phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1.02 0.96 – 1.09 0.467 1103 9766 all phecode
196 Radiotherapy Neoplasms 0.921 0.88 – 0.964 0.000368 2427 17006 all phecode
197 Chemotherapy Neoplasms 0.998 0.965 – 1.03 0.883 4952 23797 all phecode
198 Secondary malignant neoplasm Neoplasms 1.01 0.982 – 1.05 0.405 5801 23481 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.994 0.958 – 1.03 0.768 3677 21489 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.04 0.978 – 1.12 0.196 1072 10334 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.02 0.949 – 1.1 0.574 866 8538 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.02 0.942 – 1.1 0.633 767 7558 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.99 0.909 – 1.08 0.814 640 6338 all phecode
198.6 Secondary malignancy of bone Neoplasms 0.985 0.916 – 1.06 0.695 866 8307 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.976 0.867 – 1.1 0.692 336 3253 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.01 0.976 – 1.04 0.658 5693 25767 all phecode
199.4 Neurofibromatosis Neoplasms 1.05 0.84 – 1.32 0.662 88 880 all phecode
200 Myeloproliferative disease Neoplasms 1.05 0.982 – 1.12 0.159 1113 11098 all phecode
200.1 Polycythemia vera Neoplasms 1.15 0.998 – 1.33 0.0529 231 2310 all phecode
201 Hodgkin's disease Neoplasms 1.09 0.926 – 1.28 0.301 172 1705 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.02 0.961 – 1.07 0.589 1559 15571 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1 0.945 – 1.06 0.925 1329 13268 all phecode
202.21 Nodular lymphoma Neoplasms 0.945 0.871 – 1.03 0.181 693 6923 all phecode
202.22 Reticulosarcoma Neoplasms 1.2 1.01 – 1.41 0.0338 170 1693 all phecode
202.24 Large cell lymphoma Neoplasms 1.08 0.912 – 1.28 0.363 160 1586 all phecode
204 Leukemia Neoplasms 1.06 0.973 – 1.15 0.191 689 6876 all phecode
204.1 Lymphoid leukemia Neoplasms 0.91 0.791 – 1.05 0.186 236 2354 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.899 0.706 – 1.14 0.387 74 734 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.865 0.732 – 1.02 0.0881 173 1724 all phecode
204.2 Myeloid leukemia Neoplasms 1.08 0.943 – 1.23 0.273 265 2633 all phecode
204.21 Myeloid leukemia, acute Neoplasms 1.14 0.962 – 1.36 0.128 153 1516 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.17 0.876 – 1.57 0.286 61 610 all phecode
204.4 Multiple myeloma Neoplasms 1.22 1.06 – 1.41 0.00698 217 2162 all phecode
208 Benign neoplasm of colon Neoplasms 0.978 0.956 – 1 0.0709 10303 34953 all phecode
209 Neuroendocrine tumors Neoplasms 0.986 0.862 – 1.13 0.842 258 2580 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.981 0.933 – 1.03 0.437 1891 18839 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.08 1.05 – 1.11 8.13e-09 7329 36606 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.06 1 – 1.11 0.0337 1843 18412 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.996 0.945 – 1.05 0.875 1677 15527 all phecode
214 Lipoma Neoplasms 0.964 0.91 – 1.02 0.209 1437 14132 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.951 0.884 – 1.02 0.184 883 8710 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1 0.972 – 1.04 0.833 4528 39509 all phecode
216 Benign neoplasm of skin Neoplasms 0.93 0.91 – 0.951 2.32e-10 11528 34919 all phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 0.874 0.74 – 1.03 0.114 174 1701 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.843 0.801 – 0.888 8.87e-11 1786 17184 all phecode
217.1 Nevus, non-neoplastic Neoplasms 0.843 0.8 – 0.889 3.52e-10 1679 16116 all phecode
218 Benign neoplasm of uterus Neoplasms 0.982 0.948 – 1.02 0.316 4301 16661 all phecode
218.1 Uterine leiomyoma Neoplasms 0.939 0.892 – 0.989 0.017 1835 15733 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.995 0.957 – 1.03 0.786 3403 16447 all phecode
220 Benign neoplasm of ovary Neoplasms 1.02 0.952 – 1.1 0.528 893 8783 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.01 0.959 – 1.06 0.786 2042 14248 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.89 0.835 – 0.949 0.00033 1133 10663 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.06 1 – 1.11 0.0438 1801 12657 all phecode
224 Benign neoplasm of eye Neoplasms 0.956 0.879 – 1.04 0.289 691 6752 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.949 0.868 – 1.04 0.253 595 5773 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.02 0.961 – 1.09 0.484 1209 12074 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.01 0.94 – 1.08 0.806 947 9454 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.04 0.916 – 1.18 0.55 289 2890 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.02 0.958 – 1.08 0.588 1329 13264 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.01 0.958 – 1.06 0.734 1690 16896 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.1 0.998 – 1.22 0.0539 467 4644 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.933 0.864 – 1.01 0.0774 795 7941 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.04 0.941 – 1.16 0.418 435 4350 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.872 0.831 – 0.914 1.01e-08 2149 20946 all phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.847 0.798 – 0.899 4.27e-08 1356 13336 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.989 0.964 – 1.01 0.391 7767 36615 all phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.976 0.947 – 1 0.101 5743 34218 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.03 0.962 – 1.1 0.405 1031 9761 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.03 0.99 – 1.07 0.14 2910 22227 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.03 0.98 – 1.07 0.265 2265 19902 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.06 0.995 – 1.12 0.0699 1304 12479 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.04 0.982 – 1.1 0.181 1400 13425 all phecode
242.1 Graves' disease Endocrine/metabolic 1.04 0.947 – 1.15 0.402 515 5068 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.05 0.868 – 1.27 0.608 124 1224 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.04 0.914 – 1.17 0.586 292 2898 all phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 1.07 0.899 – 1.28 0.428 144 1432 all phecode
244 Hypothyroidism Endocrine/metabolic 1.07 1.04 – 1.1 1.82e-06 8099 32717 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1 0.953 – 1.06 0.898 1762 17230 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.05 0.987 – 1.12 0.125 1261 11982 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.07 1.04 – 1.1 1.68e-06 7542 32208 all phecode
245 Thyroiditis Endocrine/metabolic 1.11 1.03 – 1.19 0.00902 832 7882 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.1 1.01 – 1.2 0.0217 686 6517 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.1 1.01 – 1.19 0.0318 679 6449 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.04 1.01 – 1.07 0.00767 6129 30240 all phecode
246.2 Thyroid cyst Endocrine/metabolic 0.846 0.686 – 1.04 0.116 101 960 all phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1.01 0.944 – 1.09 0.701 886 8696 all phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.32 1.23 – 1.42 8.97e-14 1150 8340 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.24 1.22 – 1.27 5.17e-78 13947 31815 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.27 1.19 – 1.35 4.27e-14 2364 11758 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.17 0.977 – 1.39 0.0889 262 960 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.19 1.06 – 1.35 0.0036 551 2686 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.31 1.17 – 1.46 3.3e-06 784 3018 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.29 1.15 – 1.46 2.28e-05 638 2675 all phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 1.21 0.982 – 1.48 0.0734 155 850 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.33 1.3 – 1.37 1.44e-98 9843 29688 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.31 1.11 – 1.53 0.00103 282 1327 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.45 1.37 – 1.53 5.74e-36 1941 13510 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.4 1.31 – 1.5 1.35e-22 1643 9668 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.48 1.4 – 1.56 5.58e-49 2557 16502 all phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.45 1.33 – 1.58 5.63e-17 860 6143 all phecode
250.3 Insulin pump user Endocrine/metabolic 1.39 1.33 – 1.45 1.04e-44 3496 20809 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.15 1.12 – 1.18 1.15e-22 8385 30645 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.11 1.06 – 1.17 7.92e-05 1870 15861 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.16 1.12 – 1.19 1.46e-22 7553 30071 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.15 0.948 – 1.39 0.156 136 1067 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.5 1.42 – 1.59 6.72e-42 2132 13390 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.21 1.14 – 1.28 1.53e-10 1691 10517 all phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.05 0.983 – 1.13 0.142 991 8469 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.16 1.08 – 1.25 3.74e-05 1207 8570 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.05 1.01 – 1.1 0.0287 2282 22119 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.05 1 – 1.1 0.043 2088 20335 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.999 0.908 – 1.1 0.991 508 5073 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.05 0.973 – 1.13 0.219 859 8544 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.1 0.969 – 1.26 0.135 263 2621 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.16 0.909 – 1.48 0.234 83 826 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.01 0.881 – 1.17 0.843 226 2250 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.14 0.906 – 1.43 0.267 86 860 all phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 1.1 0.912 – 1.32 0.32 121 1209 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.955 0.78 – 1.17 0.655 108 1080 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.14 1.08 – 1.21 2.69e-06 1506 14869 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.03 0.923 – 1.15 0.607 373 3730 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.14 0.972 – 1.33 0.109 183 1830 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.943 0.784 – 1.13 0.528 135 1350 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.08 0.991 – 1.18 0.0793 626 6239 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.09 0.997 – 1.19 0.0575 596 5941 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.17 1.1 – 1.25 8.15e-07 1146 10513 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.3 1.2 – 1.41 6.91e-11 742 7128 all phecode
257 Testicular dysfunction Endocrine/metabolic 1.01 0.946 – 1.08 0.735 1015 9238 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.01 0.94 – 1.08 0.85 983 8933 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.18 0.942 – 1.47 0.152 91 910 all phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.968 0.786 – 1.19 0.761 109 1090 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.08 1.01 – 1.15 0.026 1038 10259 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.05 1.01 – 1.1 0.0112 2880 26812 all phecode
260.1 Cachexia Endocrine/metabolic 0.976 0.86 – 1.11 0.703 292 2911 all phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.07 1.02 – 1.13 0.00947 1691 16847 all phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.06 0.974 – 1.16 0.169 614 6140 all phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.06 0.977 – 1.16 0.151 629 6236 all phecode
260.6 Anorexia Endocrine/metabolic 1 0.931 – 1.08 0.953 868 8591 all phecode
260.7 Polyphagia Endocrine/metabolic 1.17 0.896 – 1.52 0.254 65 643 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.11 1.08 – 1.14 2.92e-14 7718 35203 all phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1.07 0.827 – 1.4 0.589 69 690 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.22 1.13 – 1.31 2.13e-07 857 8405 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.11 1.08 – 1.14 1.76e-13 7255 35225 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.973 0.732 – 1.29 0.853 52 511 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.16 1.09 – 1.23 5.82e-06 1182 11676 all phecode
263 Other nutritional deficiency Endocrine/metabolic 1.07 1.02 – 1.13 0.00788 1651 15788 all phecode
264 Lack of normal physiological development Endocrine/metabolic 0.926 0.807 – 1.06 0.271 239 2301 all phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 0.89 0.734 – 1.08 0.235 122 1220 all phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 0.959 0.761 – 1.21 0.726 81 772 all phecode
269 Proteinuria Endocrine/metabolic 1.17 1.11 – 1.23 9.11e-09 1694 13981 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.05 0.983 – 1.13 0.141 967 9575 all phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 1.01 0.859 – 1.19 0.887 170 1697 all phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 1.03 0.857 – 1.23 0.763 134 1334 all phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 1.12 0.898 – 1.38 0.322 96 954 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.05 0.966 – 1.13 0.266 737 7303 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.11 0.995 – 1.24 0.0613 384 3781 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.01 0.781 – 1.3 0.959 71 695 all phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 0.829 0.635 – 1.08 0.167 69 690 all phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.02 0.905 – 1.16 0.711 299 2984 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.01 0.972 – 1.05 0.551 2907 28132 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.01 0.971 – 1.05 0.591 2827 27425 all phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.02 0.826 – 1.26 0.863 102 1007 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.09 1.06 – 1.11 8.19e-14 18881 26670 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.09 1.06 – 1.11 7.99e-14 18843 26654 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.05 1.02 – 1.08 0.00294 5928 21600 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.11 1.05 – 1.18 0.000368 1360 11837 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.1 1.06 – 1.15 4.42e-06 3538 18449 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.01 0.897 – 1.14 0.837 313 3011 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.18 1.13 – 1.24 2.35e-14 2524 22729 all phecode
274.1 Gout Endocrine/metabolic 1.2 1.15 – 1.25 1.55e-15 2409 21991 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.19 1.11 – 1.27 2.33e-07 1082 10576 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.99 0.847 – 1.16 0.899 195 1890 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.962 0.821 – 1.13 0.633 183 1772 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.07 1.03 – 1.1 0.000174 4357 37091 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.904 0.781 – 1.05 0.173 218 2180 all phecode
275.11 Hereditary hemochromatosis Hematopoietic 0.963 0.779 – 1.19 0.732 99 990 all phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 0.901 0.684 – 1.19 0.461 62 614 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.15 1.08 – 1.22 2.43e-05 1154 11504 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.06 1.02 – 1.1 0.00308 3369 31544 all phecode
275.51 Hypocalcemia Endocrine/metabolic 1.04 0.965 – 1.11 0.326 898 8969 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.1 1.03 – 1.16 0.00198 1366 13634 all phecode
275.6 Hypercalcemia Endocrine/metabolic 1.04 0.984 – 1.1 0.16 1468 14183 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.11 1.08 – 1.14 1.72e-16 9238 37046 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.12 1.09 – 1.15 8.8e-15 6352 34366 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.15 1.05 – 1.26 0.00297 550 5434 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.11 1.06 – 1.16 3.53e-06 2514 23219 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.16 1.11 – 1.2 1.56e-12 2992 25216 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.1 1.05 – 1.16 3.51e-05 2148 20909 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.12 1.07 – 1.17 4.5e-06 2086 20332 all phecode
276.41 Acidosis Endocrine/metabolic 1.11 1.06 – 1.17 3.56e-05 1788 17572 all phecode
276.42 Alkalosis Endocrine/metabolic 1.14 1.04 – 1.26 0.0068 476 4741 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.1 1.07 – 1.14 6.37e-09 4574 34527 all phecode
276.6 Fluid overload Endocrine/metabolic 1.26 1.19 – 1.34 1.39e-14 1384 13211 all phecode
276.8 Polydipsia Endocrine/metabolic 0.882 0.729 – 1.07 0.195 124 1240 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.1 1.07 – 1.14 1.46e-08 4112 35070 all phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.4 1.25 – 1.56 1.27e-09 403 3991 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.976 0.901 – 1.06 0.554 720 7161 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.03 0.96 – 1.11 0.403 936 9270 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.08 1 – 1.17 0.0391 773 7668 all phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.29 1.2 – 1.39 5.18e-12 916 8359 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.53 1.5 – 1.56 1.81e-356 19419 27331 all phecode
278.1 Obesity Endocrine/metabolic 1.61 1.58 – 1.65 8.09e-410 17129 27321 all phecode
278.11 Morbid obesity Endocrine/metabolic 1.87 1.81 – 1.92 2.2e-406 8280 27172 all phecode
278.3 Localized adiposity Endocrine/metabolic 1.71 1.51 – 1.93 1.28e-17 324 3228 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.35 1.28 – 1.41 3.25e-33 2104 17411 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.03 0.986 – 1.07 0.21 2934 28612 all phecode
279.1 Immunity deficiency Endocrine/metabolic 0.999 0.938 – 1.06 0.974 1161 11571 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.976 0.867 – 1.1 0.693 330 3278 all phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 1.02 0.94 – 1.1 0.674 754 7516 all phecode
279.7 Other immunological findings Endocrine/metabolic 1 0.968 – 1.03 0.978 4885 36552 all phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 0.99 0.906 – 1.08 0.816 601 5988 all phecode
280 Iron deficiency anemias Hematopoietic 1.11 1.07 – 1.14 1.64e-09 4626 30873 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.1 1.07 – 1.14 4.22e-09 4484 30649 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.09 1.04 – 1.15 0.000691 1771 17196 all phecode
281 Other deficiency anemia Hematopoietic 1.07 0.973 – 1.18 0.159 519 5120 all phecode
281.1 Megaloblastic anemia Hematopoietic 1.07 0.934 – 1.23 0.325 253 2497 all phecode
281.11 Pernicious anemia Hematopoietic 1.13 0.921 – 1.39 0.242 114 1108 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.07 0.917 – 1.26 0.372 187 1817 all phecode
281.9 Deficiency anemias Hematopoietic 1.03 0.905 – 1.17 0.659 285 2830 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.19 1.05 – 1.35 0.00599 323 3188 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.17 1.01 – 1.37 0.0375 216 2113 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.28 1.09 – 1.5 0.00245 192 1920 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.22 1.03 – 1.46 0.0244 155 1550 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.22 0.93 – 1.61 0.149 64 633 all phecode
284 Aplastic anemia Hematopoietic 1.03 0.951 – 1.12 0.454 697 6943 all phecode
284.1 Pancytopenia Hematopoietic 1.04 0.952 – 1.13 0.398 612 6100 all phecode
285 Other anemias Hematopoietic 1.08 1.05 – 1.1 7.44e-11 11794 33591 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.08 1.04 – 1.12 9.26e-05 3325 27709 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.12 1.07 – 1.18 2.28e-06 2055 19939 all phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.2 1.11 – 1.28 7.72e-07 932 9106 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.04 0.955 – 1.13 0.388 690 6892 all phecode
286 Coagulation defects Hematopoietic 1.08 1.05 – 1.12 6.76e-06 3844 33384 all phecode
286.1 Congenital coagulation defects Hematopoietic 1.05 0.92 – 1.21 0.452 250 2466 all phecode
286.11 Von willebrand's disease Hematopoietic 1.13 0.902 – 1.42 0.288 83 822 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.03 0.853 – 1.25 0.747 126 1260 all phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.11 1.07 – 1.15 5.45e-08 3354 25918 all phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 0.796 0.631 – 1.01 0.0557 97 962 all phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 1.14 0.995 – 1.3 0.0598 254 2529 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.14 0.953 – 1.37 0.152 132 1294 all phecode
286.6 Defibrination syndrome Hematopoietic 1.09 1.05 – 1.14 3.57e-05 2579 25377 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.08 1.04 – 1.12 0.000103 3014 29294 all phecode
286.8 Hypercoagulable state Hematopoietic 1.1 1.02 – 1.19 0.0126 846 8437 all phecode
286.81 Primary hypercoagulable state Hematopoietic 1.09 1.01 – 1.18 0.0219 813 8111 all phecode
286.9 Abnormal coagulation profile Hematopoietic 1.13 1.06 – 1.2 0.000237 1182 11487 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.06 1.02 – 1.1 0.00286 3288 28474 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.01 0.868 – 1.17 0.927 211 2094 all phecode
287.3 Thrombocytopenia Hematopoietic 1.05 1.01 – 1.1 0.0125 2938 26323 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.08 0.988 – 1.18 0.0896 601 5994 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.979 0.893 – 1.07 0.641 569 5686 all phecode
287.4 Qualitative platelet defects Hematopoietic 1.22 0.998 – 1.5 0.0526 112 1120 all phecode
288 Diseases of white blood cells Hematopoietic 1.05 1.02 – 1.09 0.00109 4886 36527 all phecode
288.1 Decreased white blood cell count Hematopoietic 0.987 0.935 – 1.04 0.627 1599 15951 all phecode
288.11 Neutropenia Hematopoietic 0.98 0.919 – 1.05 0.55 1106 11041 all phecode
288.2 Elevated white blood cell count Hematopoietic 1.07 1.04 – 1.11 4.27e-05 4082 35079 all phecode
288.3 Eosinophilia Hematopoietic 0.835 0.713 – 0.979 0.0261 187 1866 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.01 0.963 – 1.07 0.585 1757 17434 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.971 0.904 – 1.04 0.419 918 9087 all phecode
289.4 Lymphadenitis Hematopoietic 1.07 1.03 – 1.1 0.000352 3888 34715 all phecode
289.5 Diseases of spleen Hematopoietic 1.03 0.921 – 1.15 0.624 393 3913 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.1 0.964 – 1.26 0.155 255 2550 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.1 0.987 – 1.23 0.0856 385 3813 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.02 0.956 – 1.08 0.608 1318 11547 all phecode
290.1 Dementias Mental Disorders 0.964 0.877 – 1.06 0.439 541 4910 all phecode
290.11 Alzheimer's disease Mental Disorders 0.985 0.82 – 1.18 0.874 151 1389 all phecode
290.12 Dementia with cerebral degenerations Mental Disorders 0.967 0.769 – 1.22 0.773 88 846 all phecode
290.13 Senile dementia Mental Disorders 0.915 0.813 – 1.03 0.139 340 3078 all phecode
290.16 Vascular dementia Mental Disorders 0.858 0.675 – 1.09 0.209 81 777 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.05 0.971 – 1.14 0.219 750 7358 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.947 0.881 – 1.02 0.135 886 8618 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.03 0.984 – 1.07 0.219 2550 24810 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.978 0.833 – 1.15 0.781 175 1750 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.982 0.892 – 1.08 0.716 484 4807 all phecode
291.8 Alteration of consciousness Mental Disorders 1.04 0.993 – 1.09 0.0909 2036 19974 all phecode
292 Neurological disorders Mental Disorders 1.03 1 – 1.06 0.0471 5733 38553 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.01 0.959 – 1.06 0.815 2013 19867 all phecode
292.11 Aphasia Mental Disorders 1.01 0.933 – 1.1 0.735 664 6581 all phecode
292.12 Symbolic dysfunction Mental Disorders 1.06 0.909 – 1.23 0.467 200 1988 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.966 0.866 – 1.08 0.537 389 3731 all phecode
292.3 Memory loss Mental Disorders 0.983 0.936 – 1.03 0.504 1922 18158 all phecode
292.4 Altered mental status Mental Disorders 1.07 1.02 – 1.12 0.00241 2454 22725 all phecode
292.5 Transient alteration of awareness Mental Disorders 0.979 0.884 – 1.08 0.688 430 4285 all phecode
292.6 Hallucinations Mental Disorders 1.11 0.956 – 1.28 0.176 217 2147 all phecode
293 Symptoms involving head and neck Mental Disorders 0.894 0.805 – 0.994 0.0383 414 4127 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.03 0.997 – 1.06 0.0798 4417 38609 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.09 1.01 – 1.17 0.0229 885 8229 all phecode
295.1 Schizophrenia Mental Disorders 1.08 0.895 – 1.29 0.438 138 1339 all phecode
295.2 Paranoid disorders Mental Disorders 1.15 0.942 – 1.41 0.168 118 1079 all phecode
295.3 Psychosis Mental Disorders 1.1 1.02 – 1.2 0.0193 716 6694 all phecode
296 Mood disorders Mental Disorders 1.08 1.05 – 1.1 5.53e-11 15356 20858 all phecode
296.1 Bipolar Mental Disorders 1.16 1.09 – 1.23 1.55e-06 1301 11264 all phecode
296.2 Depression Mental Disorders 1.08 1.05 – 1.1 5.85e-11 14833 20856 all phecode
296.22 Major depressive disorder Mental Disorders 1.08 1.05 – 1.1 1.43e-10 13850 20853 all phecode
297 Suicidal ideation or attempt Mental Disorders 1.13 1.05 – 1.21 0.000601 985 9050 all phecode
297.1 Suicidal ideation Mental Disorders 1.12 1.04 – 1.21 0.00361 788 7310 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.08 0.953 – 1.23 0.22 285 2654 all phecode
300 Anxiety disorders Mental Disorders 1.05 1.03 – 1.08 9.81e-06 15419 20850 all phecode
300.1 Anxiety disorder Mental Disorders 1.06 1.04 – 1.08 8.24e-07 14517 20855 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1.05 1.01 – 1.08 0.00695 5546 20512 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.04 0.978 – 1.11 0.216 1360 11377 all phecode
300.13 Phobia Mental Disorders 1.06 0.985 – 1.13 0.124 1051 9542 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.916 0.812 – 1.03 0.153 328 3018 all phecode
300.4 Dysthymic disorder Mental Disorders 1.05 1.01 – 1.1 0.0262 2420 16552 all phecode
300.8 Acute reaction to stress Mental Disorders 1.01 0.911 – 1.11 0.92 504 4825 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.12 1.03 – 1.2 0.00449 843 7909 all phecode
301 Personality disorders Mental Disorders 1.15 1.04 – 1.27 0.00711 477 4539 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.12 0.978 – 1.29 0.101 254 2393 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.974 0.936 – 1.01 0.178 3700 13808 all phecode
302.1 Decreased libido Mental Disorders 0.934 0.844 – 1.03 0.19 447 4331 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.937 0.909 – 0.965 1.52e-05 6808 20043 all phecode
303.1 Dissociative disorder Mental Disorders 1.11 0.939 – 1.32 0.216 161 1573 all phecode
303.3 Psychogenic disorder Mental Disorders 0.928 0.9 – 0.956 1.08e-06 6487 19888 all phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.933 0.845 – 1.03 0.167 471 4623 all phecode
303.4 Somatoform disorder Mental Disorders 1.01 0.952 – 1.08 0.65 1177 11180 all phecode
304 Adjustment reaction Mental Disorders 1.03 0.992 – 1.07 0.132 3888 20475 all phecode
305.2 Eating disorder Mental Disorders 1.31 1.22 – 1.41 3.64e-13 901 8329 all phecode
306 Other mental disorder Mental Disorders 1.03 0.983 – 1.09 0.196 1815 14133 all phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.1 1.01 – 1.21 0.0379 587 3527 all phecode
306.9 Tension headache Mental Disorders 1.03 0.948 – 1.11 0.515 753 7277 all phecode
312 Conduct disorders Mental Disorders 1.09 0.95 – 1.24 0.227 254 2501 all phecode
312.3 Impulse control disorder Mental Disorders 1.09 0.859 – 1.4 0.465 74 736 all phecode
313 Pervasive developmental disorders Mental Disorders 1.04 0.984 – 1.1 0.167 1571 14633 all phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1.05 0.988 – 1.11 0.122 1392 13190 all phecode
313.2 Tics and stuttering Mental Disorders 1.01 0.796 – 1.29 0.917 77 770 all phecode
313.3 Autism Mental Disorders 0.876 0.67 – 1.14 0.33 64 621 all phecode
315 Develomental delays and disorders Mental Disorders 1.07 0.98 – 1.16 0.136 684 6788 all phecode
315.1 Learning disorder Mental Disorders 1.23 0.991 – 1.52 0.0606 87 860 all phecode
315.2 Speech and language disorder Mental Disorders 0.971 0.848 – 1.11 0.67 254 2539 all phecode
316 Substance addiction and disorders Mental Disorders 1.14 1.1 – 1.18 2.75e-12 3682 32680 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.996 0.914 – 1.09 0.927 634 6331 all phecode
317 Alcohol-related disorders Mental Disorders 1.05 1 – 1.09 0.0411 2525 22920 all phecode
317.1 Alcoholism Mental Disorders 1.03 0.981 – 1.08 0.233 1986 19339 all phecode
317.11 Alcoholic liver damage Mental Disorders 0.984 0.886 – 1.09 0.769 408 4080 all phecode
318 Tobacco use disorder Mental Disorders 1.17 1.15 – 1.2 1.06e-36 8622 34842 all phecode
320 Meningitis Neurological 1.02 0.915 – 1.14 0.706 382 3820 all phecode
323 Encephalitis Neurological 1.08 0.92 – 1.26 0.355 181 1809 all phecode
323.8 Encephalitis, non-infectious Neurological 1.09 0.92 – 1.3 0.311 153 1527 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.06 0.937 – 1.21 0.34 288 2880 all phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 1.11 0.83 – 1.48 0.482 53 530 all phecode
327 Sleep disorders Neurological 1.16 1.14 – 1.19 2.19e-46 14941 31602 all phecode
327.1 Hypersomnia Neurological 1.08 1.03 – 1.13 0.00235 2061 19110 all phecode
327.3 Sleep apnea Neurological 1.23 1.2 – 1.26 2.74e-67 10909 31304 all phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1.06 0.965 – 1.17 0.221 492 4784 all phecode
327.32 Obstructive sleep apnea Neurological 1.24 1.21 – 1.27 2.24e-60 8744 30530 all phecode
327.4 Insomnia Neurological 1.07 1.04 – 1.1 1.06e-05 5524 30960 all phecode
327.41 Organic or persistent insomnia Neurological 1 0.945 – 1.07 0.875 1265 12120 all phecode
327.5 Parasomnia Neurological 1.16 1.06 – 1.26 0.000919 604 5913 all phecode
327.6 Circadian rhythm sleep disorder Neurological 1.04 0.911 – 1.19 0.552 274 2666 all phecode
327.7 Sleep related movement disorders Neurological 1.14 1.09 – 1.21 2.82e-07 1786 17323 all phecode
327.71 Restless legs syndrome Neurological 1.16 1.09 – 1.22 3.1e-07 1570 15360 all phecode
327.72 Sleep related leg cramps Neurological 1.02 0.802 – 1.29 0.892 83 822 all phecode
331 Other cerebral degenerations Neurological 0.929 0.856 – 1.01 0.0733 717 7024 all phecode
331.1 Hydrocephalus Neurological 0.933 0.823 – 1.06 0.278 284 2836 all phecode
331.9 Cerebral degeneration, unspecified Neurological 0.953 0.857 – 1.06 0.37 419 4026 all phecode
332 Parkinson's disease Neurological 0.99 0.89 – 1.1 0.845 415 4128 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.05 1.01 – 1.09 0.0158 2868 26583 all phecode
333.1 Essential tremor Neurological 0.979 0.904 – 1.06 0.608 725 7163 all phecode
333.2 Myoclonus Neurological 1.15 0.975 – 1.36 0.0968 159 1590 all phecode
333.4 Torsion dystonia Neurological 0.843 0.752 – 0.946 0.00356 352 3504 all phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 0.895 0.713 – 1.12 0.337 89 890 all phecode
334 Degenerative disease of the spinal cord Neurological 1.12 1.05 – 1.2 0.00114 1058 10562 all phecode
334.1 Spinocerebellar disease Neurological 1.07 0.842 – 1.36 0.58 79 790 all phecode
334.2 Anterior horn cell disease Neurological 1.1 0.896 – 1.36 0.355 110 1080 all phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 1.03 0.801 – 1.33 0.802 71 693 all phecode
335 Multiple sclerosis Neurological 1.07 0.959 – 1.19 0.235 396 3951 all phecode
337 Disorders of the autonomic nervous system Neurological 1.04 0.96 – 1.12 0.367 808 7413 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.07 0.954 – 1.19 0.258 370 3164 all phecode
338 Pain Neurological 1.07 1.05 – 1.09 3.83e-12 20346 26417 all phecode
338.1 Acute pain Neurological 1.06 1.04 – 1.08 8.79e-08 15582 26313 all phecode
338.2 Chronic pain Neurological 1.11 1.09 – 1.14 8.31e-19 10994 26368 all phecode
339 Other headache syndromes Neurological 1.05 1.02 – 1.07 0.000172 9242 34658 all phecode
340 Migraine Neurological 1.04 1.01 – 1.07 0.00692 6708 30587 all phecode
340.1 Migrain with aura Neurological 1.03 0.996 – 1.07 0.0775 3624 23684 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.1 0.914 – 1.33 0.31 133 1330 all phecode
342 Hemiplegia Neurological 1.02 0.927 – 1.13 0.641 464 4607 all phecode
343 Infantile cerebral palsy Neurological 0.969 0.772 – 1.22 0.783 85 847 all phecode
344 Other paralytic syndromes Neurological 1.04 0.959 – 1.13 0.342 682 6808 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.02 0.973 – 1.06 0.476 2553 25307 all phecode
345.1 Epilepsy Neurological 1 0.925 – 1.08 0.973 747 7465 all phecode
345.11 Generalized convulsive epilepsy Neurological 0.972 0.845 – 1.12 0.689 233 2330 all phecode
345.12 Partial epilepsy Neurological 0.998 0.909 – 1.09 0.96 534 5335 all phecode
345.3 Convulsions Neurological 1.02 0.972 – 1.06 0.486 2396 23796 all phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.975 0.833 – 1.14 0.748 183 1824 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.99 0.936 – 1.05 0.724 1472 14587 all phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.909 0.746 – 1.11 0.342 120 1181 all phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 0.98 0.797 – 1.2 0.847 110 1100 all phecode
347 Cataplexy and narcolepsy Neurological 1.12 0.899 – 1.4 0.312 101 1010 all phecode
348 Other conditions of brain Neurological 1.06 1.01 – 1.11 0.0283 1793 17894 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.05 0.978 – 1.13 0.178 905 9034 all phecode
348.4 Cerebral cysts Neurological 1.03 0.892 – 1.19 0.678 229 2290 all phecode
348.7 Coma Neurological 1.03 0.894 – 1.19 0.686 229 2275 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.09 1.01 – 1.17 0.0212 853 8479 all phecode
348.9 Other conditions of brain, NOS Neurological 0.982 0.939 – 1.03 0.418 2341 23287 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.07 0.998 – 1.15 0.0555 941 9385 all phecode
350 Abnormal movement Neurological 1.04 1.01 – 1.07 0.00894 6706 38762 all phecode
350.1 Abnormal involuntary movements Neurological 1.04 1.01 – 1.09 0.0232 3273 30524 all phecode
350.2 Abnormality of gait Neurological 1.05 1.01 – 1.09 0.00949 3920 30520 all phecode
350.3 Lack of coordination Neurological 0.96 0.899 – 1.02 0.216 1062 10554 all phecode
350.5 Abnormal reflex Neurological 0.994 0.855 – 1.16 0.941 200 1988 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 1 0.915 – 1.1 0.937 558 5576 all phecode
351 Other peripheral nerve disorders Neurological 1.1 1.07 – 1.13 9.91e-12 7401 34460 all phecode
352 Disorders of other cranial nerves Neurological 1.02 0.966 – 1.07 0.5 1714 17106 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.975 0.888 – 1.07 0.602 535 5344 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.05 0.973 – 1.13 0.209 783 7826 all phecode
353 Nerve root and plexus disorders Neurological 1.07 1.03 – 1.11 0.000105 4256 33369 all phecode
353.1 Nerve plexus lesions Neurological 1.07 0.963 – 1.2 0.197 390 3900 all phecode
353.2 Nerve root lesions Neurological 0.986 0.816 – 1.19 0.88 130 1287 all phecode
355 Complex regional/central pain syndrome Neurological 1.08 0.98 – 1.18 0.124 531 5295 all phecode
355.1 Chronic pain syndrome Neurological 1.16 1.07 – 1.24 0.000118 843 8386 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.07 1.02 – 1.12 0.00328 2335 20731 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.09 1.05 – 1.13 5.67e-06 3472 29956 all phecode
358 Myoneural disorders Neurological 1.09 1.02 – 1.16 0.00709 1147 11391 all phecode
358.1 Myasthenia gravis Neurological 0.94 0.769 – 1.15 0.547 109 1082 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.954 0.895 – 1.02 0.158 1134 11274 all phecode
359.1 Muscular dystrophies Neurological 0.82 0.615 – 1.09 0.177 64 632 all phecode
359.2 Myopathy Neurological 0.969 0.907 – 1.04 0.355 1092 10843 all phecode
360 Disorders of the globe Sense Organs 0.921 0.764 – 1.11 0.392 131 1276 all phecode
360.2 Progressive myopia Sense Organs 0.836 0.64 – 1.09 0.189 65 640 all phecode
361 Retinal detachments and defects Sense Organs 0.951 0.878 – 1.03 0.216 733 7131 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.871 0.769 – 0.988 0.0315 302 2962 all phecode
362 Other retinal disorders Sense Organs 0.99 0.953 – 1.03 0.603 3569 22997 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.981 0.935 – 1.03 0.443 2172 15483 all phecode
362.21 Macular degeneration, dry Sense Organs 0.896 0.802 – 1 0.0504 419 3438 all phecode
362.22 Macular degeneration, wet Sense Organs 1.07 0.887 – 1.29 0.483 148 1184 all phecode
362.23 Cystoid macular degeneration of retina Sense Organs 0.926 0.832 – 1.03 0.162 408 3839 all phecode
362.26 Macular puckering of retina Sense Organs 0.978 0.912 – 1.05 0.525 976 8610 all phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.889 0.805 – 0.983 0.0217 488 4558 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.986 0.936 – 1.04 0.588 1883 13955 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.05 0.983 – 1.13 0.14 976 8527 all phecode
362.31 Separation of retinal layers Sense Organs 0.987 0.889 – 1.1 0.801 413 4056 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.988 0.908 – 1.08 0.784 662 5933 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.898 0.804 – 1 0.0548 392 3787 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.911 0.786 – 1.06 0.215 215 2103 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.18 1.03 – 1.36 0.0178 241 2368 all phecode
362.9 Retinal edema Sense Organs 1.17 1.04 – 1.32 0.0113 324 2936 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.913 0.828 – 1.01 0.0678 492 4746 all phecode
363.3 Chorioretinal scars Sense Organs 0.863 0.767 – 0.971 0.0139 332 3184 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.96 0.899 – 1.02 0.221 1132 10772 all phecode
364.1 Corneal opacity Sense Organs 0.956 0.859 – 1.06 0.413 394 3846 all phecode
364.2 Corneal edema Sense Organs 1.1 0.912 – 1.33 0.31 123 1208 all phecode
364.4 Corneal degenerations Sense Organs 0.976 0.877 – 1.09 0.663 402 3962 all phecode
364.41 Keratoconus Sense Organs 0.726 0.564 – 0.933 0.0124 75 739 all phecode
364.5 Corneal dystrophy Sense Organs 0.958 0.867 – 1.06 0.407 502 4682 all phecode
364.51 Fuchs' dystrophy Sense Organs 0.902 0.786 – 1.04 0.143 266 2521 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.912 0.728 – 1.14 0.424 91 885 all phecode
365 Glaucoma Sense Organs 0.976 0.935 – 1.02 0.274 2672 21326 all phecode
365.1 Open-angle glaucoma Sense Organs 0.944 0.869 – 1.02 0.169 705 6491 all phecode
365.11 Primary open angle glaucoma Sense Organs 0.909 0.815 – 1.01 0.0879 403 3681 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.982 0.852 – 1.13 0.802 251 2370 all phecode
366 Cataract Sense Organs 0.992 0.965 – 1.02 0.574 8611 28043 all phecode
366.1 Nonsenile Cataract Sense Organs 0.93 0.798 – 1.08 0.352 207 1979 all phecode
366.2 Senile cataract Sense Organs 0.984 0.952 – 1.02 0.319 5480 24980 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.974 0.951 – 0.999 0.0413 8967 37779 all phecode
367.1 Myopia Sense Organs 0.942 0.912 – 0.972 0.000215 5014 34677 all phecode
367.2 Astigmatism Sense Organs 0.948 0.916 – 0.982 0.00256 4161 32463 all phecode
367.8 Hypermetropia Sense Organs 0.953 0.908 – 1 0.0503 2039 18599 all phecode
367.9 Blindness and low vision Sense Organs 1.06 0.994 – 1.12 0.0782 1277 12356 all phecode
368 Visual disturbances Sense Organs 1.02 0.99 – 1.05 0.202 5715 39599 all phecode
368.1 Amblyopia Sense Organs 1.06 0.971 – 1.15 0.204 651 6479 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.04 0.971 – 1.11 0.287 1087 10786 all phecode
368.3 Anisometropia Sense Organs 0.85 0.734 – 0.984 0.0295 219 2168 all phecode
368.4 Visual field defects Sense Organs 0.99 0.929 – 1.06 0.756 1132 11173 all phecode
368.9 Subjective visual disturbances Sense Organs 1.01 0.949 – 1.08 0.675 1070 10620 all phecode
368.91 Psychophysical visual disturbances Sense Organs 1.24 1.02 – 1.5 0.0322 120 1171 all phecode
369 Infection of the eye Sense Organs 0.953 0.917 – 0.991 0.0154 3185 28240 all phecode
369.2 Eye infection, viral Sense Organs 0.936 0.849 – 1.03 0.18 502 4954 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.957 0.917 – 0.997 0.0371 2716 24970 all phecode
370 Keratitis Sense Organs 0.926 0.874 – 0.982 0.0107 1365 13169 all phecode
370.1 Corneal ulcer Sense Organs 0.874 0.758 – 1.01 0.0661 223 2194 all phecode
370.2 Superficial keratitis Sense Organs 0.944 0.861 – 1.04 0.222 546 5393 all phecode
370.3 Keratoconjunctivitis Sense Organs 0.977 0.898 – 1.06 0.591 649 6263 all phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.97 0.823 – 1.14 0.713 179 1677 all phecode
371 Inflammation of the eye Sense Organs 0.957 0.925 – 0.989 0.00944 4414 32310 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.01 0.924 – 1.11 0.772 541 5278 all phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.958 0.891 – 1.03 0.241 906 8939 all phecode
371.21 Allergic conjunctivitis Sense Organs 0.954 0.881 – 1.03 0.243 756 7515 all phecode
371.3 Inflammation of eyelids Sense Organs 0.949 0.913 – 0.985 0.00662 3398 26983 all phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 0.826 0.682 – 1 0.0496 133 1291 all phecode
372 Disorders of conjunctiva Sense Organs 0.944 0.885 – 1.01 0.08 1118 10728 all phecode
374 Other disorders of eyelids Sense Organs 0.933 0.896 – 0.972 0.000818 2940 24188 all phecode
374.1 Ectropion or entropion Sense Organs 0.847 0.762 – 0.941 0.002 431 4084 all phecode
374.2 Lagophthalmos Sense Organs 0.958 0.832 – 1.1 0.552 235 2335 all phecode
374.3 Ptosis of eyelid Sense Organs 0.946 0.886 – 1.01 0.0975 1102 10734 all phecode
374.6 Dermatochalasis Sense Organs 0.987 0.922 – 1.06 0.713 1040 9720 all phecode
375 Disorders of lacrimal system Sense Organs 0.983 0.947 – 1.02 0.356 3694 26045 all phecode
375.1 Dry eyes Sense Organs 0.975 0.941 – 1.01 0.162 4040 26751 all phecode
375.2 Epiphora Sense Organs 0.978 0.88 – 1.09 0.673 442 4354 all phecode
376 Disorders of the orbit Sense Organs 0.99 0.883 – 1.11 0.866 352 3508 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.06 0.983 – 1.13 0.136 913 9021 all phecode
377.1 Optic atrophy Sense Organs 0.97 0.852 – 1.1 0.649 283 2793 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.08 0.983 – 1.18 0.113 585 5775 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.982 0.924 – 1.04 0.554 1275 12460 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1 0.93 – 1.08 0.955 828 8130 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.974 0.826 – 1.15 0.75 170 1686 all phecode
378.5 Paralytic strabismus Sense Organs 0.939 0.838 – 1.05 0.277 349 3437 all phecode
379 Other disorders of eye Sense Organs 0.968 0.937 – 1 0.0485 5046 29999 all phecode
379.1 Scleritis and episcleritis Sense Organs 0.919 0.778 – 1.08 0.318 176 1743 all phecode
379.2 Disorders of vitreous body Sense Organs 0.958 0.923 – 0.995 0.0282 3634 23186 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.909 0.759 – 1.09 0.301 135 1258 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.01 0.887 – 1.14 0.911 287 2833 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.09 0.962 – 1.23 0.184 304 2948 all phecode
379.51 Pigmentary iris degeneration Sense Organs 0.852 0.66 – 1.1 0.222 77 731 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.01 0.95 – 1.08 0.684 1129 11130 all phecode
380 Disorders of external ear Sense Organs 0.926 0.884 – 0.97 0.00107 2242 20393 all phecode
380.1 Otitis externa Sense Organs 0.974 0.921 – 1.03 0.364 1469 14580 all phecode
380.4 Impacted cerumen Sense Organs 0.919 0.881 – 0.959 0.000107 2648 23557 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.998 0.965 – 1.03 0.909 4255 36417 all phecode
381.1 Otitis media Sense Organs 1.03 0.991 – 1.07 0.138 3079 29813 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.04 0.994 – 1.08 0.0925 2610 25602 all phecode
381.2 Eustachian tube disorders Sense Organs 0.926 0.88 – 0.974 0.003 1816 17827 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.16 0.98 – 1.38 0.0837 153 1530 all phecode
381.9 Otorrhea Sense Organs 1.13 1.01 – 1.27 0.0262 372 3713 all phecode
382 Otalgia Sense Organs 1.03 0.975 – 1.08 0.327 1884 18673 all phecode
383 Otosclerosis Sense Organs 0.933 0.77 – 1.13 0.475 124 1240 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.02 0.929 – 1.12 0.685 516 5156 all phecode
384.1 Myringitis Sense Organs 0.835 0.618 – 1.13 0.241 51 502 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.03 0.925 – 1.14 0.608 403 4029 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.01 0.909 – 1.11 0.905 432 4320 all phecode
385.3 Cholesteatoma Sense Organs 1.03 0.909 – 1.17 0.631 277 2770 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.946 0.781 – 1.15 0.57 118 1180 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.03 0.98 – 1.08 0.244 1882 18186 all phecode
386.1 Meniere's disease Sense Organs 1.07 0.95 – 1.21 0.255 319 3156 all phecode
386.2 Peripheral or central vertigo Sense Organs 1.03 0.979 – 1.09 0.23 1586 15423 all phecode
386.21 Central origin vertigo Sense Organs 1.05 0.987 – 1.12 0.122 1208 11844 all phecode
386.3 Labyrinthitis Sense Organs 1.04 0.978 – 1.1 0.231 1482 14530 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.04 1.01 – 1.06 0.0109 6933 38286 all phecode
388 Other disorders of ear Sense Organs 0.99 0.924 – 1.06 0.773 960 9501 all phecode
389 Hearing loss Sense Organs 0.983 0.958 – 1.01 0.181 8182 38069 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.944 0.912 – 0.977 0.00117 4107 29258 all phecode
389.2 Conductive hearing loss Sense Organs 0.976 0.909 – 1.05 0.499 905 9042 all phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.914 0.781 – 1.07 0.264 192 1808 all phecode
389.4 Tinnitus Sense Organs 0.924 0.883 – 0.966 0.000557 2291 22130 all phecode
389.5 Disorders of acoustic nerve Sense Organs 1.06 0.876 – 1.27 0.572 124 1229 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.06 1 – 1.12 0.0357 1458 13732 all phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 1.08 0.96 – 1.21 0.205 350 3415 all phecode
394.2 Mitral valve disease Circulatory System 1.01 0.913 – 1.11 0.863 462 4560 all phecode
394.3 Aortic valve disease Circulatory System 1.14 0.963 – 1.34 0.13 176 1691 all phecode
394.4 Acute rheumatic heart disease Circulatory System 0.961 0.728 – 1.27 0.778 55 546 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.07 0.978 – 1.17 0.142 587 5739 all phecode
395 Heart valve disorders Circulatory System 1.02 0.98 – 1.05 0.405 3976 28748 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.967 0.923 – 1.01 0.156 2175 20441 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.06 1.01 – 1.12 0.0135 2060 17194 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.03 0.935 – 1.14 0.537 493 4864 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.09 0.884 – 1.34 0.419 108 1080 all phecode
395.6 Heart valve replaced Circulatory System 1.08 1.02 – 1.16 0.013 1177 10833 all phecode
396 Abnormal heart sounds Circulatory System 1.02 0.989 – 1.05 0.206 4718 34395 all phecode
401 Hypertension Circulatory System 1.26 1.23 – 1.29 3.33e-94 23317 23367 all phecode
401.1 Essential hypertension Circulatory System 1.26 1.23 – 1.29 1.47e-95 23158 23364 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.36 1.31 – 1.42 1.51e-46 3503 14616 all phecode
401.21 Hypertensive heart disease Circulatory System 1.31 1.22 – 1.42 1.11e-12 893 6607 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.34 1.28 – 1.41 2.08e-34 2584 13072 all phecode
401.3 Other hypertensive complications Circulatory System 1.25 1.19 – 1.31 3.32e-22 2679 15833 all phecode
411 Ischemic Heart Disease Circulatory System 1.15 1.12 – 1.18 6.9e-24 8807 30299 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.16 1.08 – 1.25 3.63e-05 937 8574 all phecode
411.2 Myocardial infarction Circulatory System 1.18 1.14 – 1.22 1.2e-17 3594 21716 all phecode
411.3 Angina pectoris Circulatory System 1.18 1.13 – 1.23 5.21e-13 2485 18304 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.15 1.12 – 1.18 2.79e-21 7555 27492 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.18 0.993 – 1.4 0.06 156 1529 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.15 1.12 – 1.19 1.93e-19 6331 25741 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.19 1.08 – 1.32 0.000628 442 4211 all phecode
414 Other forms of chronic heart disease Circulatory System 1.12 1.07 – 1.16 6.66e-08 3101 22616 all phecode
414.2 ASCVD Circulatory System 1.1 1.01 – 1.19 0.0256 718 6816 all phecode
415 Pulmonary heart disease Circulatory System 1.13 1.09 – 1.17 2e-10 3366 30208 all phecode
415.1 Acute pulmonary heart disease Circulatory System 1.12 1.06 – 1.18 9.54e-06 1912 19014 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.12 1.06 – 1.18 9.8e-06 1906 18953 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.16 1.1 – 1.22 1.59e-08 1808 17605 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.1 1.01 – 1.19 0.0269 706 7032 all phecode
416 Cardiomegaly Circulatory System 1.1 1.03 – 1.17 0.00267 1254 12372 all phecode
418 Nonspecific chest pain Circulatory System 1.05 1.02 – 1.07 3.64e-05 12650 33952 all phecode
418.1 Precordial pain Circulatory System 1.03 0.974 – 1.09 0.295 1471 13782 all phecode
420 Carditis Circulatory System 1.05 0.999 – 1.11 0.0549 1588 15680 all phecode
420.1 Myocarditis Circulatory System 1.22 0.982 – 1.53 0.0726 97 958 all phecode
420.2 Pericarditis Circulatory System 1.03 0.96 – 1.12 0.372 842 8402 all phecode
420.21 Acute pericarditis Circulatory System 1.21 1.03 – 1.42 0.0224 177 1764 all phecode
420.22 Chronic pericarditis Circulatory System 1.16 0.953 – 1.42 0.137 117 1153 all phecode
420.3 Endocarditis Circulatory System 1.09 1.01 – 1.18 0.0252 764 7535 all phecode
425 Cardiomyopathy Circulatory System 1.12 1.07 – 1.18 2.45e-06 2078 19881 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.13 1.07 – 1.18 1.38e-06 1989 19025 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.09 0.94 – 1.26 0.259 208 2050 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.15 0.987 – 1.33 0.0735 201 1992 all phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.06 0.937 – 1.2 0.357 317 3170 all phecode
425.8 Other cardiomyopathy Circulatory System 1.17 0.93 – 1.47 0.18 95 931 all phecode
426 Cardiac conduction disorders Circulatory System 1.07 1.04 – 1.09 8.37e-08 12327 25440 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.12 1.07 – 1.18 1.34e-05 1903 11501 all phecode
426.21 First degree AV block Circulatory System 1.11 1.04 – 1.18 0.00171 1313 8899 all phecode
426.22 Mobitz II AV block Circulatory System 1.03 0.771 – 1.37 0.859 64 553 all phecode
426.23 Second degree AV block Circulatory System 1.03 0.89 – 1.2 0.655 216 1925 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.07 0.97 – 1.19 0.17 461 3823 all phecode
426.25 Other heart block Circulatory System 1.05 0.905 – 1.22 0.513 203 1803 all phecode
426.3 Bundle branch block Circulatory System 1.09 1.04 – 1.14 0.000652 2306 13999 all phecode
426.31 Right bundle branch block Circulatory System 1.07 1.01 – 1.14 0.0207 1423 10758 all phecode
426.32 Left bundle branch block Circulatory System 1.13 1.05 – 1.21 0.000823 969 8110 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.984 0.779 – 1.24 0.894 82 820 all phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.07 1.04 – 1.09 5.96e-07 10577 25186 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.13 1.04 – 1.23 0.00497 679 6650 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.1 1.04 – 1.16 0.000494 1754 11536 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.12 1.05 – 1.19 0.000971 1171 8184 all phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.1 1.02 – 1.18 0.0177 846 7320 all phecode
427 Cardiac dysrhythmias Circulatory System 1.04 1.02 – 1.06 0.000107 17397 25735 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.04 0.995 – 1.09 0.0786 2474 18178 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.04 0.99 – 1.1 0.113 1595 14293 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.07 0.999 – 1.14 0.0523 1181 9915 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.09 1.05 – 1.12 3.16e-06 5313 18688 all phecode
427.21 Atrial fibrillation Circulatory System 1.08 1.04 – 1.12 8.86e-06 5188 18409 all phecode
427.22 Atrial flutter Circulatory System 1.07 1.02 – 1.13 0.0103 1693 11042 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.05 1.02 – 1.08 0.000705 8688 25552 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.04 0.947 – 1.14 0.409 536 5233 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.888 0.769 – 1.02 0.104 216 2118 all phecode
427.42 Cardiac arrest Circulatory System 1.06 0.954 – 1.18 0.271 410 4034 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.03 1 – 1.06 0.0268 6905 25457 all phecode
427.6 Premature beats Circulatory System 1.01 0.966 – 1.06 0.622 2359 16248 all phecode
427.61 Supraventricular premature beats Circulatory System 1.06 0.971 – 1.15 0.199 670 6287 all phecode
427.7 Tachycardia NOS Circulatory System 1.09 1.05 – 1.12 2.77e-07 5124 25531 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.07 0.998 – 1.16 0.0554 912 7501 all phecode
427.9 Palpitations Circulatory System 0.991 0.957 – 1.03 0.593 4430 24505 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.2 1.16 – 1.25 2.15e-24 4300 23663 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.21 1.16 – 1.25 2.85e-23 3756 22446 all phecode
428.2 Heart failure NOS Circulatory System 1.23 1.19 – 1.28 3.41e-27 3701 21722 all phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.21 1.15 – 1.27 1.77e-12 1765 14476 all phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.28 1.21 – 1.35 2.33e-18 1648 13395 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.06 1.04 – 1.08 1.7e-07 12635 32504 all phecode
429.1 Heart transplant/surgery Circulatory System 1.08 1.01 – 1.15 0.019 1219 11696 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.09 1.06 – 1.12 1.73e-08 6322 29232 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.05 1.02 – 1.08 8.06e-05 9650 32421 all phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.12 1.03 – 1.21 0.00775 723 7072 all phecode
430 Intracranial hemorrhage Circulatory System 0.963 0.892 – 1.04 0.341 789 7842 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.994 0.87 – 1.14 0.931 261 2610 all phecode
430.2 Intracerebral hemorrhage Circulatory System 0.987 0.881 – 1.1 0.816 368 3671 all phecode
430.3 Subdural hemorrhage Circulatory System 0.916 0.803 – 1.04 0.188 272 2680 all phecode
433 Cerebrovascular disease Circulatory System 1.07 1.04 – 1.11 4.49e-06 5463 32242 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.07 1.02 – 1.12 0.00876 1978 16212 all phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.17 1.02 – 1.34 0.0284 260 2517 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.08 0.847 – 1.38 0.536 80 789 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.1 1.05 – 1.15 2.26e-05 2437 21732 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.1 1.05 – 1.15 5.47e-05 2357 21103 all phecode
433.3 Cerebral ischemia Circulatory System 1.04 1 – 1.09 0.0511 2780 22868 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.05 1.01 – 1.1 0.0277 2409 20762 all phecode
433.5 Cerebral aneurysm Circulatory System 1.02 0.921 – 1.12 0.737 474 4724 all phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.07 0.966 – 1.18 0.2 464 4518 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.12 1.04 – 1.22 0.00519 695 6822 all phecode
440 Atherosclerosis Circulatory System 1.12 1.07 – 1.17 2.66e-07 2477 19724 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.988 0.856 – 1.14 0.864 231 2291 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.13 1.06 – 1.19 4.08e-05 1516 13532 all phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.2 1.06 – 1.37 0.00497 274 2669 all phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.1 1.03 – 1.18 0.00567 1040 9647 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.16 1.08 – 1.25 1e-04 846 8124 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.06 0.96 – 1.16 0.262 515 5115 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.05 0.918 – 1.21 0.457 240 2387 all phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1 0.839 – 1.19 0.997 154 1536 all phecode
442 Other aneurysm Circulatory System 1.09 1.04 – 1.13 8.7e-05 2779 21466 all phecode
442.1 Aortic aneurysm Circulatory System 1.09 1.04 – 1.15 0.000363 2054 16492 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.07 1.01 – 1.14 0.0304 1189 10558 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.07 0.921 – 1.25 0.36 202 2002 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.962 0.818 – 1.13 0.638 179 1765 all phecode
442.4 Arterial dissection Circulatory System 0.965 0.825 – 1.13 0.661 184 1840 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.08 0.966 – 1.2 0.183 399 3978 all phecode
443 Peripheral vascular disease Circulatory System 1.08 1.04 – 1.13 0.00011 3086 24814 all phecode
443.1 Raynaud's syndrome Circulatory System 0.862 0.797 – 0.934 0.000254 742 7390 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.3 1.13 – 1.51 0.000387 220 2087 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.08 1.03 – 1.13 0.000591 2557 21985 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.16 1.11 – 1.21 2.79e-10 2341 18862 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.1 1.02 – 1.18 0.0139 848 8423 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.05 0.929 – 1.18 0.443 313 3099 all phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 1.07 0.905 – 1.28 0.412 155 1548 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.02 0.92 – 1.13 0.726 460 4559 all phecode
446.4 Wegener's granulomatosis Circulatory System 0.843 0.686 – 1.04 0.105 109 1075 all phecode
446.5 Giant cell arteritis Circulatory System 0.83 0.652 – 1.06 0.129 79 749 all phecode
446.9 Arteritis NOS Circulatory System 1.07 0.941 – 1.21 0.308 289 2876 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.07 1.03 – 1.12 0.000935 2647 22765 all phecode
447.1 Stricture of artery Circulatory System 1.1 1 – 1.21 0.0405 523 5163 all phecode
447.7 Aortic ectasia Circulatory System 1.02 0.948 – 1.1 0.562 804 7938 all phecode
448 Disease of capillaries Circulatory System 0.851 0.8 – 0.906 3.76e-07 1237 12127 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.08 1.03 – 1.13 0.0021 2104 20985 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.05 0.973 – 1.14 0.198 738 7355 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.09 0.946 – 1.25 0.241 244 2437 all phecode
452 Other venous embolism and thrombosis Circulatory System 1.12 1.08 – 1.15 4.6e-12 4957 29867 all phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1.01 0.891 – 1.15 0.843 276 2747 all phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1.12 1.08 – 1.16 1.29e-08 3260 26940 all phecode
452.8 Postphlebitic syndrome Circulatory System 1.09 0.919 – 1.29 0.325 154 1529 all phecode
453 Chronic venous hypertension Circulatory System 1.14 0.986 – 1.33 0.0758 220 2168 all phecode
454 Varicose veins Circulatory System 1.06 1.02 – 1.1 0.00644 2827 24555 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1.08 1.04 – 1.13 0.000304 2469 21426 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.1 1.04 – 1.16 0.00108 1565 15056 all phecode
455 Hemorrhoids Circulatory System 0.961 0.932 – 0.99 0.0089 5799 29818 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.08 1.04 – 1.12 0.000199 3097 24898 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.09 1.04 – 1.15 0.000299 2095 15309 all phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.11 0.989 – 1.25 0.0765 324 3221 all phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.09 1.04 – 1.14 0.00087 1973 14689 all phecode
458 Hypotension Circulatory System 1.11 1.07 – 1.14 1.43e-10 5091 32185 all phecode
458.1 Orthostatic hypotension Circulatory System 1.07 1.01 – 1.14 0.0203 1344 12938 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.09 1.02 – 1.16 0.0109 1109 11012 all phecode
458.9 Hypotension NOS Circulatory System 1.11 1.07 – 1.15 6.58e-10 4618 31186 all phecode
459 Other disorders of circulatory system Circulatory System 1.09 1.06 – 1.12 2.07e-10 7825 34792 all phecode
459.1 Hemorrhage NOS Circulatory System 1.01 0.936 – 1.09 0.801 834 8215 all phecode
459.7 Blood vessel replaced Circulatory System 1.17 1.1 – 1.24 4.94e-07 1305 13023 all phecode
459.9 Circulatory disease NEC Circulatory System 1.09 1.06 – 1.12 1.23e-09 6706 33592 all phecode
464 Acute sinusitis Respiratory 0.975 0.944 – 1.01 0.127 4792 32137 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.974 0.95 – 0.997 0.0285 9601 35915 all phecode
465.2 Acute pharyngitis Respiratory 0.963 0.933 – 0.993 0.0155 5310 32365 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.01 0.912 – 1.12 0.829 443 4428 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.927 0.881 – 0.976 0.0037 1797 17640 all phecode
471 Nasal polyps Respiratory 0.951 0.871 – 1.04 0.266 592 5881 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.965 0.917 – 1.02 0.169 1797 16986 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1.01 0.969 – 1.05 0.674 2983 25244 all phecode
473.1 Chronic laryngitis Respiratory 1.04 0.805 – 1.35 0.756 68 674 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.98 0.9 – 1.07 0.652 628 6254 all phecode
473.4 Voice disturbance Respiratory 1.01 0.962 – 1.05 0.801 2336 21975 all phecode
474 Acute and chronic tonsillitis Respiratory 1.01 0.941 – 1.09 0.735 880 7892 all phecode
474.1 Acute tonsillitis Respiratory 0.869 0.773 – 0.978 0.0196 335 3181 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.05 0.965 – 1.14 0.273 700 6445 all phecode
475 Chronic sinusitis Respiratory 0.97 0.937 – 1 0.0738 4378 27891 all phecode
475.9 Postnasal drip Respiratory 0.901 0.839 – 0.968 0.0046 922 9017 all phecode
476 Allergic rhinitis Respiratory 0.988 0.966 – 1.01 0.27 12687 28117 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.07 1.01 – 1.15 0.0278 1150 11318 all phecode
478 Throat pain Respiratory 0.965 0.87 – 1.07 0.5 426 4195 all phecode
479 Other upper respiratory disease Respiratory 1.01 0.977 – 1.04 0.668 5627 28048 all phecode
480 Pneumonia Respiratory 1.07 1.04 – 1.1 5.49e-06 5947 37034 all phecode
480.1 Bacterial pneumonia Respiratory 1.08 1.01 – 1.15 0.0219 1155 11495 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.1 1 – 1.2 0.0462 568 5644 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.03 0.862 – 1.22 0.779 153 1523 all phecode
480.13 MRSA pneumonia Respiratory 1.09 0.898 – 1.33 0.38 117 1165 all phecode
480.2 Viral pneumonia Respiratory 1.13 0.976 – 1.32 0.101 202 1992 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.06 0.896 – 1.26 0.481 159 1590 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.13 0.94 – 1.35 0.196 135 1312 all phecode
481 Influenza Respiratory 1.02 0.962 – 1.08 0.488 1355 13284 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.04 1 – 1.08 0.0396 3412 29871 all phecode
495 Asthma Respiratory 1.11 1.08 – 1.14 1.47e-16 8671 33569 all phecode
495.1 Chronic obstructive asthma Respiratory 1.2 1.08 – 1.33 0.000952 397 3925 all phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 1.07 0.839 – 1.37 0.586 81 802 all phecode
495.2 Asthma with exacerbation Respiratory 1.08 1.02 – 1.14 0.00467 1629 16033 all phecode
496 Chronic airway obstruction Respiratory 1.16 1.13 – 1.2 1.57e-21 5343 28343 all phecode
496.1 Emphysema Respiratory 1.14 1.09 – 1.19 5.52e-08 2134 19414 all phecode
496.2 Chronic bronchitis Respiratory 1.2 1.16 – 1.25 1.62e-25 4128 26624 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.21 1.17 – 1.26 1.07e-24 3747 25467 all phecode
496.3 Bronchiectasis Respiratory 0.963 0.877 – 1.06 0.432 549 5453 all phecode
497 Bronchitis Respiratory 1.09 1.03 – 1.14 0.00112 1946 18824 all phecode
498 Acute bronchospasm Respiratory 1.35 1.22 – 1.5 3.42e-09 496 4943 all phecode
499 Cystic fibrosis Respiratory 0.963 0.809 – 1.15 0.673 151 1510 all phecode
500 Lung disease due to external agents Respiratory 1.12 1.02 – 1.23 0.014 557 5551 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.04 0.832 – 1.29 0.746 92 920 all phecode
500.2 Pneumoconiosis Respiratory 1.1 0.874 – 1.39 0.411 78 764 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.1 1.01 – 1.2 0.0246 634 6225 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.02 0.946 – 1.1 0.591 815 8076 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.19 1.11 – 1.28 4.69e-06 835 8243 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.04 0.951 – 1.14 0.39 595 5878 all phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 0.959 0.848 – 1.08 0.499 311 3084 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.09 1.04 – 1.15 0.00118 1638 15749 all phecode
506 Empyema and pneumothorax Respiratory 1.07 1.03 – 1.12 0.000445 2894 25235 all phecode
507 Pleurisy; pleural effusion Respiratory 1.09 1.05 – 1.14 1.98e-05 2916 26208 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.09 1.04 – 1.14 0.000112 2382 22588 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.12 1.09 – 1.16 5.7e-11 4032 29477 all phecode
509.1 Respiratory failure Respiratory 1.15 1.1 – 1.21 1.47e-08 1937 18949 all phecode
509.2 Respiratory insufficiency Respiratory 1.11 1.04 – 1.18 0.00141 1174 11679 all phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.1 1.04 – 1.16 0.000545 1689 16489 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.17 1.11 – 1.23 3.92e-09 1741 17249 all phecode
510 Other diseases of lung Respiratory 1.03 1 – 1.07 0.0284 5503 35907 all phecode
510.2 Lung transplant Respiratory 0.949 0.807 – 1.12 0.524 176 1757 all phecode
512 Other symptoms of respiratory system Respiratory 1.07 1.05 – 1.09 1.31e-11 18621 28154 all phecode
512.1 Wheezing Respiratory 1.19 1.12 – 1.26 4.46e-09 1409 13516 all phecode
512.2 Painful respiration Respiratory 1.04 0.996 – 1.09 0.077 2309 21263 all phecode
512.3 Abnormal chest sounds Respiratory 0.962 0.851 – 1.09 0.533 291 2845 all phecode
512.7 Shortness of breath Respiratory 1.12 1.09 – 1.15 5.06e-19 10034 28081 all phecode
512.8 Cough Respiratory 1.07 1.04 – 1.09 5.06e-07 9501 28148 all phecode
512.9 Other dyspnea Respiratory 1.1 1.07 – 1.12 3.23e-14 10804 28104 all phecode
513 Respiratory abnormalities Respiratory 1.1 1.08 – 1.12 8.33e-18 12932 33822 all phecode
513.3 Hypoventilation Respiratory 1.16 1.08 – 1.25 7.54e-05 880 8646 all phecode
513.31 Apnea Respiratory 1.11 1 – 1.22 0.0463 462 4607 all phecode
513.32 Orthopnea Respiratory 1.11 0.964 – 1.29 0.141 220 2160 all phecode
513.4 Hyperventilation Respiratory 1.22 1.11 – 1.34 4.5e-05 515 5124 all phecode
513.8 Disorders of diaphragm Respiratory 1.01 0.881 – 1.16 0.888 258 2557 all phecode
514 Abnormal findings examination of lungs Respiratory 1.03 1 – 1.06 0.0474 5365 34834 all phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 0.92 0.804 – 1.05 0.22 258 2580 all phecode
514.2 Solitary pulmonary nodule Respiratory 1.03 0.987 – 1.07 0.189 3018 27338 all phecode
516 Abnormal sputum Respiratory 1.11 1.03 – 1.21 0.00797 735 7332 all phecode
516.1 Hemoptysis Respiratory 1.11 1.02 – 1.22 0.0157 611 6080 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.06 1.03 – 1.09 7.86e-05 6458 39057 all phecode
519.1 Tracheostomy complications Respiratory 1.24 1.07 – 1.43 0.00374 214 2136 all phecode
519.2 Respiratory complications Respiratory 1.04 0.941 – 1.15 0.434 445 4430 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.02 0.963 – 1.07 0.548 1588 15787 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.06 1.03 – 1.1 0.000296 4706 34489 all phecode
520 Disorders of tooth development Digestive 1.02 0.915 – 1.14 0.705 369 3690 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.11 0.942 – 1.32 0.207 165 1642 all phecode
520.2 Disturbances in tooth eruption Digestive 1 0.872 – 1.15 0.98 218 2172 all phecode
521 Diseases of hard tissues of teeth Digestive 1.17 1.09 – 1.26 1.28e-05 898 8954 all phecode
521.1 Dental caries Digestive 1.18 1.1 – 1.27 7.45e-06 837 8349 all phecode
521.2 Dental abrasion, erosion and attrition Digestive 1.09 0.81 – 1.46 0.576 52 510 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.22 1.11 – 1.34 2.22e-05 535 5340 all phecode
522.5 Periapical abscess Digestive 1.23 1.12 – 1.36 3.87e-05 459 4583 all phecode
523 Gingival and periodontal diseases Digestive 1.14 1.06 – 1.24 0.000881 718 7180 all phecode
523.1 Gingivitis Digestive 1.06 0.892 – 1.27 0.493 142 1418 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.21 1.08 – 1.35 0.000824 364 3636 all phecode
523.31 Acute periodontitis Digestive 1.21 1.08 – 1.37 0.00161 311 3109 all phecode
523.32 Chronic periodontitis Digestive 1.16 0.959 – 1.41 0.125 122 1204 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.821 0.732 – 0.92 0.000729 363 3630 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.818 0.709 – 0.943 0.00571 220 2200 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.15 1.08 – 1.23 2.35e-05 1039 10382 all phecode
525.1 Loss of teeth or edentulism Digestive 1.13 1.01 – 1.26 0.0308 374 3731 all phecode
526 Diseases of the jaws Digestive 0.95 0.911 – 0.991 0.0164 2680 26455 all phecode
526.1 Cysts of the jaws Digestive 0.921 0.806 – 1.05 0.227 247 2470 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.781 0.679 – 0.898 0.000521 241 2383 all phecode
526.4 Temporomandibular joint disorders Digestive 0.934 0.883 – 0.987 0.0159 1504 15025 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.942 0.885 – 1 0.0607 1187 11858 all phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 0.896 0.828 – 0.97 0.00675 741 7400 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.998 0.881 – 1.13 0.97 287 2864 all phecode
526.8 Exostosis of jaw Digestive 0.972 0.724 – 1.3 0.849 53 521 all phecode
526.9 Jaw disease NOS Digestive 0.928 0.842 – 1.02 0.133 487 4867 all phecode
527 Diseases of the salivary glands Digestive 1.04 0.992 – 1.1 0.0954 1781 17771 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.03 0.782 – 1.35 0.852 58 579 all phecode
527.2 Sialoadenitis Digestive 1.09 0.978 – 1.22 0.121 394 3936 all phecode
527.7 Disturbance of salivary secretion Digestive 1.03 0.961 – 1.1 0.406 952 9481 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.1 0.958 – 1.26 0.179 254 2540 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.98 0.94 – 1.02 0.353 2643 26197 all phecode
528.1 Stomatitis and mucositis Digestive 0.954 0.878 – 1.04 0.275 668 6657 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.03 0.887 – 1.19 0.709 211 2110 all phecode
528.12 Oral aphthae Digestive 0.98 0.847 – 1.13 0.786 215 2137 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.23 1.07 – 1.41 0.00357 235 2338 all phecode
528.4 Cysts of oral soft tissues Digestive 0.795 0.656 – 0.965 0.0203 124 1229 all phecode
528.41 Cyst of the salivary gland Digestive 0.908 0.709 – 1.16 0.443 77 760 all phecode
528.5 Diseases of lips Digestive 1.01 0.91 – 1.11 0.888 462 4602 all phecode
528.6 Leukoplakia of oral mucosa Digestive 0.97 0.806 – 1.17 0.747 137 1370 all phecode
528.7 Sialolithiasis Digestive 1.11 0.939 – 1.32 0.217 163 1623 all phecode
529 Diseases and other conditions of the tongue Digestive 1.09 1 – 1.19 0.038 690 6878 all phecode
529.1 Glossitis Digestive 1.14 0.938 – 1.38 0.189 129 1281 all phecode
529.6 Glossodynia Digestive 1.15 0.974 – 1.35 0.1 168 1652 all phecode
530 Diseases of esophagus Digestive 1.1 1.08 – 1.13 2.04e-21 17081 27931 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.11 1.08 – 1.13 2.68e-21 16572 27931 all phecode
530.11 GERD Digestive 1.11 1.08 – 1.13 7.97e-22 16143 27929 all phecode
530.12 Ulcer of esophagus Digestive 1.01 0.912 – 1.13 0.788 400 3983 all phecode
530.13 Barrett's esophagus Digestive 1.16 1.08 – 1.26 0.000145 762 7584 all phecode
530.14 Reflux esophagitis Digestive 1.07 1.02 – 1.13 0.00733 1900 17495 all phecode
530.15 Eosinophilic esophagitis Digestive 1.06 0.912 – 1.22 0.468 221 2210 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.1 1.01 – 1.19 0.0275 651 6473 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.09 1.02 – 1.17 0.0141 911 8971 all phecode
530.5 Disorders of esophageal motility Digestive 1.11 1.01 – 1.22 0.0294 548 5432 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.881 0.731 – 1.06 0.187 129 1265 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.07 0.846 – 1.34 0.587 82 812 all phecode
530.9 Heartburn Digestive 1.1 1.04 – 1.16 0.000818 1519 14928 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.09 1.04 – 1.14 0.000475 2073 20617 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.05 0.941 – 1.17 0.383 391 3883 all phecode
531.2 Gastric ulcer Digestive 1.13 1.06 – 1.2 0.000184 1201 11970 all phecode
531.3 Duodenal ulcer Digestive 1.03 0.935 – 1.14 0.522 467 4640 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.03 0.954 – 1.11 0.446 804 8018 all phecode
531.5 Gastrojejunal ulcer Digestive 1.25 1.05 – 1.49 0.012 150 1500 all phecode
532 Dysphagia Digestive 1.1 1.06 – 1.13 2.87e-09 5585 26852 all phecode
535 Gastritis and duodenitis Digestive 1.07 1.02 – 1.11 0.00175 2799 27335 all phecode
535.1 Acute gastritis Digestive 1.14 1.07 – 1.22 3.28e-05 1178 11750 all phecode
535.2 Atrophic gastritis Digestive 1.01 0.895 – 1.13 0.924 344 3413 all phecode
535.6 Duodenitis Digestive 1.01 0.899 – 1.14 0.862 334 3337 all phecode
535.8 Other specified gastritis Digestive 1.01 0.927 – 1.1 0.822 638 6354 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.01 0.95 – 1.07 0.745 1255 12511 all phecode
536 Disorders of function of stomach Digestive 1.03 0.985 – 1.07 0.217 2911 27685 all phecode
536.3 Gastroparesis Digestive 1.05 0.97 – 1.14 0.225 706 6901 all phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.07 0.961 – 1.19 0.222 407 4059 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.01 0.966 – 1.06 0.602 2150 21094 all phecode
537 Other disorders of stomach and duodenum Digestive 1.07 1.03 – 1.12 0.000245 3183 30048 all phecode
537.1 Lesions of stomach and duodenum Digestive 1.09 0.926 – 1.27 0.311 173 1725 all phecode
539 Bariatric surgery Digestive 1.71 1.62 – 1.81 3.71e-75 1509 15074 all phecode
540 Appendiceal conditions Digestive 0.997 0.904 – 1.1 0.952 495 4948 all phecode
540.1 Appendicitis Digestive 0.973 0.876 – 1.08 0.618 425 4239 all phecode
540.11 Acute appendicitis Digestive 0.933 0.831 – 1.05 0.238 353 3511 all phecode
550 Abdominal hernia Digestive 1.04 1.02 – 1.07 0.00207 6768 37731 all phecode
550.1 Inguinal hernia Digestive 0.838 0.796 – 0.882 2.11e-11 1744 16488 all phecode
550.2 Diaphragmatic hernia Digestive 1.06 1.02 – 1.11 0.00336 2817 25849 all phecode
550.3 Femoral hernia Digestive 0.817 0.674 – 0.991 0.0399 131 1291 all phecode
550.4 Umbilical hernia Digestive 1.06 1 – 1.13 0.0392 1313 13110 all phecode
550.5 Ventral hernia Digestive 1.17 1.12 – 1.23 9.66e-12 2241 22163 all phecode
550.6 Incisional hernia Digestive 1.19 1.12 – 1.26 9.34e-09 1313 13111 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.06 1 – 1.12 0.0445 1536 15153 all phecode
555.1 Regional enteritis Digestive 1.1 1.02 – 1.18 0.00818 919 9095 all phecode
555.2 Ulcerative colitis Digestive 0.986 0.919 – 1.06 0.696 937 9315 all phecode
555.21 Ulcerative colitis (chronic) Digestive 0.921 0.839 – 1.01 0.0814 537 5315 all phecode
556 Ulceration of the lower GI tract Digestive 1.1 1.01 – 1.2 0.0274 632 6267 all phecode
556.1 Ulceration of intestine Digestive 1.08 0.983 – 1.18 0.111 551 5451 all phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 0.977 0.844 – 1.13 0.758 214 2093 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.2 1.14 – 1.27 3.15e-12 1716 16490 all phecode
557.1 Celiac disease Digestive 0.977 0.88 – 1.08 0.658 421 4026 all phecode
558 Noninfectious gastroenteritis Digestive 1.06 1.03 – 1.1 0.00107 3458 26408 all phecode
559 Ileostomy status Digestive 1.06 0.986 – 1.13 0.119 957 9565 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.06 1.02 – 1.1 0.00688 3004 24851 all phecode
560.1 Paralytic ileus Digestive 1.05 0.991 – 1.1 0.106 1627 15714 all phecode
560.2 Impaction of intestine Digestive 1.07 0.956 – 1.19 0.244 387 3779 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.941 0.823 – 1.08 0.373 266 2647 all phecode
560.4 Other intestinal obstruction Digestive 1.06 1.01 – 1.12 0.0292 1651 16170 all phecode
561 Symptoms involving digestive system Digestive 1.02 0.976 – 1.06 0.386 2608 21766 all phecode
562 Diverticulosis and diverticulitis Digestive 1.03 0.999 – 1.06 0.058 6295 23431 all phecode
562.1 Diverticulosis Digestive 1.03 0.998 – 1.06 0.0641 6246 23383 all phecode
562.2 Diverticulitis Digestive 1.04 0.982 – 1.09 0.197 1611 15162 all phecode
564 Functional digestive disorders Digestive 1.06 1.03 – 1.08 2.49e-06 11411 28676 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.03 0.995 – 1.07 0.0939 3457 22266 all phecode
564.9 Personal history of diseases of digestive system Digestive 1.08 1.04 – 1.12 0.000142 3074 25861 all phecode
565 Anal and rectal conditions Digestive 0.989 0.952 – 1.03 0.547 3355 30757 all phecode
565.1 Anal and rectal polyp Digestive 1 0.943 – 1.06 0.965 1305 12649 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.12 1.06 – 1.19 0.000147 1364 13616 all phecode
568 Other disorders of peritoneum Digestive 1.12 1.07 – 1.18 1.01e-05 1705 17038 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.15 1.08 – 1.22 7.53e-06 1247 12468 all phecode
569 Other disorders of intestine Digestive 1.05 1.03 – 1.08 9.04e-05 8079 35231 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.06 0.945 – 1.2 0.302 326 3260 all phecode
569.2 Gastrointestinal complications Digestive 1.16 1.1 – 1.23 2.68e-07 1395 13933 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.11 1.08 – 1.15 6.39e-11 4610 32562 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.12 1.08 – 1.16 2.63e-11 4342 32234 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.09 1.02 – 1.17 0.00835 1018 10095 all phecode
571.6 Primary biliary cirrhosis Digestive 1.01 0.864 – 1.19 0.88 179 1790 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.08 1.01 – 1.16 0.0322 950 9498 all phecode
571.81 Portal hypertension Digestive 1.07 0.974 – 1.16 0.165 573 5730 all phecode
572 Ascites (non malignant) Digestive 1.05 1 – 1.1 0.0309 2278 22675 all phecode
573 Other disorders of liver Digestive 1.06 1.03 – 1.1 6e-05 5599 33620 all phecode
573.1 Chronic passive congestion of liver Digestive 1.38 1.14 – 1.66 0.000801 136 1359 all phecode
573.2 Liver replaced by transplant Digestive 1.06 0.936 – 1.21 0.346 292 2920 all phecode
573.3 Hepatomegaly Digestive 1.16 1.05 – 1.28 0.00281 470 4700 all phecode
573.4 Acute and subacute necrosis of liver Digestive 0.977 0.864 – 1.1 0.71 316 3149 all phecode
573.5 Jaundice (not of newborn) Digestive 1.05 0.977 – 1.12 0.194 958 9496 all phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.03 0.984 – 1.07 0.234 2756 26470 all phecode
573.7 Abnormal results of function study of liver Digestive 1.02 0.981 – 1.06 0.304 3018 27774 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.03 1 – 1.07 0.0517 4679 33866 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.1 1.06 – 1.14 8.93e-07 3177 30809 all phecode
574.1 Cholelithiasis Digestive 1.1 1.05 – 1.14 7.11e-06 2924 28874 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.15 1.03 – 1.3 0.0157 342 3412 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.06 0.964 – 1.16 0.241 553 5501 all phecode
574.2 Calculus of bile duct Digestive 1.03 0.954 – 1.11 0.466 852 8503 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.12 1.04 – 1.21 0.00242 822 8181 all phecode
575 Other biliary tract disease Digestive 1.05 0.999 – 1.09 0.0545 2266 22555 all phecode
575.1 Cholangitis Digestive 1.02 0.907 – 1.14 0.783 354 3530 all phecode
575.2 Obstruction of bile duct Digestive 1.16 1.06 – 1.26 0.00107 621 6201 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.901 0.777 – 1.04 0.167 207 2063 all phecode
575.7 Other disorders of gallbladder Digestive 1.02 0.947 – 1.09 0.661 939 9382 all phecode
575.8 Other disorders of biliary tract Digestive 1.07 1 – 1.14 0.0459 1154 11523 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.03 0.904 – 1.18 0.645 260 2600 all phecode
577 Diseases of pancreas Digestive 1.05 1 – 1.1 0.048 2225 22106 all phecode
577.1 Acute pancreatitis Digestive 1.1 1.03 – 1.17 0.00258 1212 12110 all phecode
577.2 Chronic pancreatitis Digestive 1.16 1.05 – 1.28 0.00327 495 4950 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.988 0.901 – 1.08 0.806 570 5601 all phecode
578 Gastrointestinal hemorrhage Digestive 1.03 0.993 – 1.06 0.122 4554 37045 all phecode
578.1 Hematemesis Digestive 1.12 1.01 – 1.23 0.0256 485 4842 all phecode
578.2 Blood in stool Digestive 1.05 1.01 – 1.09 0.0276 2743 26554 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.01 0.964 – 1.06 0.695 2210 21750 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.05 0.998 – 1.11 0.0572 1562 15345 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.09 1.06 – 1.13 1.67e-07 4431 34209 all phecode
579.2 Splenomegaly Digestive 1.16 1.07 – 1.25 0.000386 730 7262 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.03 0.972 – 1.09 0.329 1410 13877 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.2 1.14 – 1.27 2.67e-12 1881 15516 all phecode
580.1 Glomerulonephritis Genitourinary 1.21 1.08 – 1.35 0.000883 401 3992 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.14 0.956 – 1.37 0.141 146 1440 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.4 1.14 – 1.72 0.00122 114 1128 all phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.12 0.847 – 1.47 0.434 61 600 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.27 1.11 – 1.45 0.000477 277 2760 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.13 0.976 – 1.3 0.104 221 2193 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.22 1.15 – 1.29 3.16e-11 1502 11930 all phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.29 1.2 – 1.38 6.97e-12 992 7228 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.14 1.05 – 1.24 0.00167 683 6612 all phecode
580.4 Renal sclerosis, NOS Genitourinary 1.15 1.02 – 1.29 0.0214 340 3400 all phecode
585 Renal failure Genitourinary 1.15 1.12 – 1.18 3.56e-23 7470 32340 all phecode
585.1 Acute renal failure Genitourinary 1.16 1.12 – 1.2 2.4e-16 4265 27230 all phecode
585.2 Renal failure NOS Genitourinary 1.19 1.1 – 1.28 6.16e-06 832 8162 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.18 1.14 – 1.21 2.14e-24 5580 29470 all phecode
585.31 Renal dialysis Genitourinary 1.14 1.05 – 1.23 0.00127 747 7423 all phecode
585.32 End stage renal disease Genitourinary 1.22 1.14 – 1.31 6.07e-09 1007 9783 all phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.2 1.15 – 1.25 3.1e-19 3209 21312 all phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.23 1.15 – 1.32 7.39e-09 977 9190 all phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.17 1.1 – 1.24 1.21e-06 1227 11191 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.1 1.07 – 1.13 1.98e-11 7628 34189 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.14 1.01 – 1.28 0.0291 349 3480 all phecode
586.11 Small kidney Genitourinary 1.16 1 – 1.34 0.0435 210 2093 all phecode
586.12 Vesicoureteral reflux Genitourinary 1.07 0.891 – 1.29 0.455 136 1360 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.02 0.962 – 1.08 0.498 1381 12912 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.17 0.999 – 1.36 0.052 187 1862 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.02 0.965 – 1.07 0.551 1821 17115 all phecode
587 Kidney replaced by transpant Genitourinary 1.11 1.03 – 1.2 0.00642 819 8134 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.22 1.14 – 1.31 1.73e-08 976 9389 all phecode
588.1 Renal osteodystrophy Genitourinary 1.1 0.966 – 1.25 0.151 290 2900 all phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.22 1.13 – 1.33 7.12e-07 755 7275 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.15 1.08 – 1.23 5.46e-05 1007 9834 all phecode
590 Pyelonephritis Genitourinary 1.12 1.06 – 1.18 9.44e-05 1461 14350 all phecode
591 Urinary tract infection Genitourinary 1.02 0.999 – 1.05 0.0585 9873 32513 all phecode
592 Cystitis and urethritis Genitourinary 1.01 0.969 – 1.05 0.684 3038 24207 all phecode
592.1 Cystitis Genitourinary 1.01 0.97 – 1.05 0.623 2880 23279 all phecode
592.11 Acute cystitis Genitourinary 1.01 0.956 – 1.06 0.796 1783 16452 all phecode
592.12 Chronic cystitis Genitourinary 0.937 0.815 – 1.08 0.359 239 2343 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.963 0.868 – 1.07 0.475 431 4310 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.981 0.843 – 1.14 0.801 210 2093 all phecode
593 Hematuria Genitourinary 1.03 1 – 1.07 0.0408 4859 32063 all phecode
593.1 Gross hematuria Genitourinary 1.07 1.01 – 1.13 0.0183 1585 14824 all phecode
593.2 Microscopic hematuria Genitourinary 1.02 0.951 – 1.09 0.632 1049 10301 all phecode
594 Urinary calculus Genitourinary 1.07 1.04 – 1.1 5.24e-07 6707 38209 all phecode
594.1 Calculus of kidney Genitourinary 1.07 1.04 – 1.1 1.25e-06 6273 38051 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.11 0.993 – 1.24 0.0666 366 3638 all phecode
594.3 Calculus of ureter Genitourinary 1.05 0.988 – 1.11 0.119 1361 13561 all phecode
594.8 Renal colic Genitourinary 1.15 1.02 – 1.28 0.0192 356 3560 all phecode
595 Hydronephrosis Genitourinary 1.06 1 – 1.11 0.0449 1670 16658 all phecode
596 Other disorders of bladder Genitourinary 0.994 0.956 – 1.03 0.772 3074 28020 all phecode
596.1 Bladder neck obstruction Genitourinary 1.02 0.912 – 1.13 0.765 400 3942 all phecode
596.5 Functional disorders of bladder Genitourinary 0.979 0.93 – 1.03 0.436 1719 17049 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.969 0.91 – 1.03 0.314 1211 11998 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.96 0.883 – 1.04 0.343 661 6537 all phecode
597.2 Urinary complications NEC Genitourinary 1 0.937 – 1.07 0.976 1049 10479 all phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.03 0.881 – 1.2 0.711 189 1873 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.03 0.853 – 1.24 0.783 138 1356 all phecode
598.4 Other cells and casts in urine Genitourinary 1.03 0.843 – 1.25 0.784 122 1192 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.987 – 1.03 0.43 14168 30681 all phecode
599.1 Urinary obstruction Genitourinary 0.888 0.819 – 0.963 0.00385 728 6861 all phecode
599.2 Retention of urine Genitourinary 1 0.97 – 1.03 0.898 5034 28305 all phecode
599.3 Dysuria Genitourinary 1 0.968 – 1.04 0.96 4397 27849 all phecode
599.4 Urinary incontinence Genitourinary 1.03 0.998 – 1.06 0.0677 5599 26960 all phecode
599.5 Frequency of urination and polyuria Genitourinary 0.978 0.948 – 1.01 0.159 5498 28723 all phecode
599.6 Oliguria and anuria Genitourinary 1.13 1.03 – 1.23 0.00966 599 5902 all phecode
599.7 Urethral discharge Genitourinary 1.09 0.898 – 1.33 0.376 118 1175 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1 0.972 – 1.03 0.883 5446 27963 all phecode
599.9 Other abnormality of urination Genitourinary 0.984 0.946 – 1.02 0.431 3041 24877 all phecode
600 Hyperplasia of prostate Genitourinary 0.949 0.912 – 0.988 0.0101 4063 11364 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.978 0.915 – 1.05 0.515 1044 9665 all phecode
601.1 Prostatitis Genitourinary 0.868 0.786 – 0.957 0.0046 477 4596 all phecode
601.11 Acute prostatitis Genitourinary 0.948 0.779 – 1.15 0.593 124 1200 all phecode
601.12 Chronic prostatitis Genitourinary 0.929 0.745 – 1.16 0.516 95 943 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.07 0.962 – 1.19 0.209 389 3822 all phecode
601.4 Balanoposthitis Genitourinary 1.05 0.871 – 1.27 0.59 127 1224 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.16 0.979 – 1.37 0.088 161 1591 all phecode
602 Other disorders of prostate Genitourinary 0.891 0.795 – 0.999 0.0483 361 3399 all phecode
602.3 Dysplasia of prostate Genitourinary 1.04 0.812 – 1.33 0.756 77 730 all phecode
603 Other disorders of testis Genitourinary 1.03 0.934 – 1.14 0.529 440 4354 all phecode
603.1 Hydrocele Genitourinary 1.04 0.917 – 1.17 0.574 293 2882 all phecode
603.2 Spermatocele Genitourinary 0.955 0.805 – 1.13 0.599 156 1539 all phecode
604 Disorders of penis Genitourinary 0.994 0.916 – 1.08 0.881 685 6748 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.34 1.13 – 1.59 0.000895 155 1540 all phecode
604.3 Peyronie's disease Genitourinary 0.899 0.777 – 1.04 0.153 215 2132 all phecode
605 Erectile dysfunction [ED] Genitourinary 0.962 0.926 – 1 0.0527 3776 12700 all phecode
608 Other disorders of male genital organs Genitourinary 0.996 0.945 – 1.05 0.896 1645 13758 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.861 0.776 – 0.956 0.00514 424 4196 all phecode
609.1 Infertility, male Genitourinary 0.876 0.774 – 0.99 0.0346 302 2992 all phecode
609.11 Azoospermia and oligospermia Genitourinary 1.11 0.888 – 1.39 0.354 95 950 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.757 0.635 – 0.904 0.00205 154 1519 all phecode
610 Benign mammary dysplasias Genitourinary 0.92 0.886 – 0.956 1.97e-05 3683 16548 all phecode
610.1 Cystic mastopathy Genitourinary 0.927 0.878 – 0.979 0.00639 1633 14191 all phecode
610.2 Fibroadenosis of breast Genitourinary 0.804 0.611 – 1.06 0.119 60 600 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.904 0.867 – 0.944 3.8e-06 2837 16430 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.911 0.856 – 0.969 0.00302 1269 12191 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.915 0.887 – 0.945 3.17e-08 6067 18690 all phecode
611.1 Abnormal mammogram Genitourinary 0.898 0.868 – 0.93 8.98e-10 4980 16120 all phecode
611.11 Mammographic microcalcification Genitourinary 0.841 0.787 – 0.899 2.95e-07 1122 10394 all phecode
611.3 Lump or mass in breast Genitourinary 0.907 0.873 – 0.943 6.63e-07 3549 18572 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.965 0.902 – 1.03 0.292 1051 10425 all phecode
612.1 Galactorrhea Genitourinary 0.983 0.822 – 1.18 0.853 139 1390 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.01 0.939 – 1.09 0.727 800 7962 all phecode
612.3 Congenital anomalies of breast Genitourinary 0.588 0.455 – 0.761 5.25e-05 83 810 all phecode
613 Other nonmalignant breast conditions Genitourinary 0.965 0.93 – 1 0.0515 3897 22072 all phecode
613.1 Inflammatory disease of breast Genitourinary 0.965 0.884 – 1.05 0.43 593 5874 all phecode
613.5 Mastodynia Genitourinary 0.963 0.913 – 1.02 0.172 1675 16203 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.928 0.863 – 0.999 0.0477 883 8754 all phecode
613.8 Other specified disorders of breast Genitourinary 0.883 0.822 – 0.948 0.000643 932 9248 all phecode
613.9 Breast disorder NOS Genitourinary 0.935 0.883 – 0.99 0.0217 1465 14174 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1 0.966 – 1.04 0.914 3715 19647 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.02 0.911 – 1.15 0.685 337 3370 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.02 0.929 – 1.13 0.629 478 4773 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.14 0.916 – 1.42 0.239 94 933 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.893 0.762 – 1.04 0.157 186 1842 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.999 0.871 – 1.15 0.988 246 2460 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.08 0.914 – 1.28 0.357 165 1639 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.998 0.959 – 1.04 0.917 3180 19539 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.06 0.928 – 1.21 0.388 264 2640 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.982 0.941 – 1.02 0.399 2732 18924 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.12 0.926 – 1.35 0.248 132 1311 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.17 1.01 – 1.35 0.0367 225 2244 all phecode
615 Endometriosis Genitourinary 1 0.952 – 1.06 0.861 1585 14666 all phecode
618 Genital prolapse Genitourinary 0.994 0.947 – 1.04 0.793 2079 17915 all phecode
618.1 Prolapse of vaginal walls Genitourinary 0.955 0.901 – 1.01 0.121 1408 13456 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.965 0.878 – 1.06 0.458 542 5390 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.945 0.834 – 1.07 0.373 317 3162 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.07 0.963 – 1.18 0.213 441 4394 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.988 0.957 – 1.02 0.446 5728 18687 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1 0.943 – 1.07 0.917 1233 12082 all phecode
619.2 Disorders of uterus, NEC Genitourinary 0.935 0.855 – 1.02 0.14 591 5897 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.935 0.847 – 1.03 0.18 483 4823 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.986 0.944 – 1.03 0.535 2525 18404 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.02 0.96 – 1.09 0.498 1189 11717 all phecode
620 Dysplasia of female genital organs Genitourinary 1.04 0.934 – 1.16 0.475 395 3950 all phecode
620.1 Dysplasia of cervix Genitourinary 1.05 0.897 – 1.23 0.542 178 1780 all phecode
621 Endometrial hyperplasia Genitourinary 1.05 0.947 – 1.17 0.352 437 4370 all phecode
622 Polyp of female genital organs Genitourinary 0.933 0.881 – 0.989 0.0187 1449 14264 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.954 0.894 – 1.02 0.16 1132 11189 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.866 0.78 – 0.962 0.00718 445 4444 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.03 0.954 – 1.11 0.457 824 8165 all phecode
624 Symptoms involving female genital tract Genitourinary 0.981 0.924 – 1.04 0.521 1348 12518 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.897 0.775 – 1.04 0.145 216 2155 all phecode
624.2 Atrophy of female genital tract Genitourinary 1.18 0.892 – 1.57 0.244 64 615 all phecode
624.9 stress incontinence, female Genitourinary 1.02 0.97 – 1.07 0.443 1935 15408 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.978 0.947 – 1.01 0.163 5653 17303 all phecode
625.1 Dyspareunia Genitourinary 0.934 0.878 – 0.993 0.0284 1267 12474 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1 0.968 – 1.03 0.998 5940 15585 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.995 0.96 – 1.03 0.795 4315 14604 all phecode
626.11 Absent or infrequent menstruation Genitourinary 1.02 0.95 – 1.09 0.658 1062 8531 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.01 0.966 – 1.07 0.571 2097 11991 all phecode
626.13 Irregular menstrual cycle Genitourinary 1 0.953 – 1.05 0.935 1957 12265 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.956 0.892 – 1.02 0.203 970 8996 all phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.966 0.868 – 1.08 0.529 394 3789 all phecode
626.2 Dysmenorrhea Genitourinary 1.03 0.973 – 1.1 0.294 1373 9857 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.97 0.861 – 1.09 0.608 336 3308 all phecode
626.8 Infertility, female Genitourinary 0.978 0.907 – 1.06 0.574 817 6741 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.941 0.908 – 0.975 0.000795 4560 14557 all phecode
627.1 Postmenopausal bleeding Genitourinary 0.967 0.906 – 1.03 0.315 1146 10338 all phecode
627.2 Symptomatic menopause Genitourinary 0.923 0.885 – 0.963 0.00022 3017 13763 all phecode
627.21 Symptomatic artificial menopause Genitourinary 0.852 0.712 – 1.02 0.08 152 1514 all phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.773 0.686 – 0.871 2.34e-05 356 3513 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.886 0.825 – 0.95 0.000716 997 9484 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.97 0.866 – 1.09 0.597 361 3580 all phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.93 0.823 – 1.05 0.241 309 3082 all phecode
628 Ovarian cyst Genitourinary 1 0.952 – 1.05 0.977 1945 13838 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.975 0.905 – 1.05 0.506 826 8047 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.913 0.803 – 1.04 0.162 273 2715 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.05 0.852 – 1.28 0.671 117 1170 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.869 0.794 – 0.951 0.00236 563 5309 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.856 0.765 – 0.958 0.00679 370 3629 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.844 0.743 – 0.957 0.00841 288 2850 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.926 0.867 – 0.99 0.0232 1080 7870 all phecode
636.1 Threatened premature labor Pregnancy Complications 0.933 0.837 – 1.04 0.213 380 3799 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.94 0.828 – 1.07 0.339 288 2868 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.948 0.857 – 1.05 0.307 441 4365 all phecode
636.8 Cervical incompetence Pregnancy Complications 1.03 0.815 – 1.31 0.779 77 770 all phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.15 0.914 – 1.45 0.23 85 850 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.02 0.933 – 1.11 0.671 585 5725 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.04 0.924 – 1.18 0.499 302 3013 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.09 0.948 – 1.24 0.234 252 2506 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.06 0.871 – 1.28 0.573 119 1190 all phecode
644 Anemia during pregnancy Pregnancy Complications 1 0.87 – 1.16 0.952 224 2224 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.02 0.945 – 1.1 0.64 855 6531 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.947 0.821 – 1.09 0.457 211 2093 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.03 0.889 – 1.18 0.732 222 2213 all phecode
647.3 Major puerperal infection Pregnancy Complications 1.14 0.883 – 1.47 0.314 65 650 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.988 0.928 – 1.05 0.702 1275 8010 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.04 0.951 – 1.13 0.419 649 5687 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1 0.915 – 1.09 0.995 587 5463 all phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.985 0.845 – 1.15 0.849 207 2055 all phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 0.915 0.788 – 1.06 0.247 204 2040 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.936 0.886 – 0.989 0.0195 1624 10064 all phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 0.97 0.89 – 1.06 0.498 616 5533 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.99 0.921 – 1.06 0.775 898 7014 all phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 1.02 0.789 – 1.31 0.891 66 660 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.932 0.866 – 1 0.0585 887 6802 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.04 0.905 – 1.19 0.583 236 2351 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.01 0.85 – 1.19 0.928 158 1580 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.875 0.748 – 1.02 0.0964 184 1814 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.13 1.1 – 1.16 3.99e-18 6500 38394 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.03 0.972 – 1.1 0.289 1256 11462 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.12 1.05 – 1.2 0.00101 1007 9981 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.17 1.11 – 1.22 1.67e-10 2123 19952 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.18 1.13 – 1.23 1.5e-12 2252 20944 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.18 1.12 – 1.24 4.12e-10 1820 16893 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.2 1.13 – 1.26 1e-10 1572 15588 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.08 1.03 – 1.13 0.000622 2257 21750 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.13 1.03 – 1.24 0.00777 558 5504 all phecode
686.2 Impetigo Dermatologic 1.09 0.977 – 1.21 0.125 414 4117 all phecode
686.3 Pilonidal cyst Dermatologic 1.05 0.885 – 1.24 0.595 160 1594 all phecode
686.4 Pyogenic granuloma Dermatologic 0.995 0.84 – 1.18 0.955 158 1570 all phecode
686.5 Pyoderma Dermatologic 1.23 0.934 – 1.61 0.141 63 630 all phecode
687 Symptoms affecting skin Dermatologic 0.972 0.922 – 1.03 0.299 1690 16343 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.999 0.972 – 1.03 0.927 7007 34623 all phecode
687.3 Changes in skin texture Dermatologic 1.08 0.973 – 1.2 0.15 415 4121 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.05 1.02 – 1.08 0.00102 6375 34216 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.939 0.917 – 0.962 3.85e-07 9311 37335 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.904 0.876 – 0.933 3.53e-10 5184 31581 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.904 0.876 – 0.933 3.51e-10 5174 31553 all phecode
691 Congenital anomalies of skin Dermatologic 0.962 0.877 – 1.05 0.406 541 5337 all phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 1.12 0.855 – 1.48 0.404 62 613 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.91 0.865 – 0.957 0.000247 1861 17936 all phecode
694.1 Vitiligo Dermatologic 1.06 0.882 – 1.27 0.546 137 1347 all phecode
694.2 Other dyschromia Dermatologic 0.899 0.852 – 0.948 8.14e-05 1674 16183 all phecode
694.3 Vascular disorders of skin Dermatologic 1.11 0.873 – 1.41 0.39 82 819 all phecode
695 Erythematous conditions Dermatologic 1.01 0.978 – 1.05 0.468 4120 30247 all phecode
695.1 Toxic erythema Dermatologic 1.11 0.868 – 1.43 0.394 70 688 all phecode
695.2 Bullous dermatoses Dermatologic 1.06 0.837 – 1.35 0.616 85 805 all phecode
695.3 Rosacea Dermatologic 0.904 0.859 – 0.951 0.000111 1816 17663 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.06 0.978 – 1.16 0.149 672 6686 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.12 0.975 – 1.28 0.11 247 2437 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.05 0.968 – 1.15 0.227 637 6337 all phecode
695.7 Prurigo and Lichen Dermatologic 0.971 0.889 – 1.06 0.511 605 5986 all phecode
695.8 Other specified erythematous conditions Dermatologic 1.09 1.01 – 1.18 0.0216 812 7980 all phecode
695.81 Erythema nodosum Dermatologic 0.887 0.665 – 1.18 0.413 55 550 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.15 1.05 – 1.24 0.0013 679 6756 all phecode
696 Psoriasis and related disorders Dermatologic 1.02 0.967 – 1.08 0.415 1401 13832 all phecode
696.3 Pityriasis Dermatologic 0.875 0.704 – 1.09 0.228 92 904 all phecode
696.4 Psoriasis Dermatologic 1.05 0.986 – 1.11 0.132 1311 12976 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.04 0.977 – 1.11 0.224 1200 11867 all phecode
696.42 Psoriatic arthropathy Dermatologic 0.983 0.863 – 1.12 0.791 282 2810 all phecode
697 Sarcoidosis Dermatologic 1.09 0.971 – 1.23 0.142 333 3330 all phecode
698 Pruritus and related conditions Dermatologic 0.981 0.937 – 1.03 0.418 2254 21889 all phecode
700 Corns and callosities Dermatologic 1.07 1.01 – 1.13 0.0321 1373 10894 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.992 0.967 – 1.02 0.564 7651 38050 all phecode
701.1 Keratoderma, acquired Dermatologic 1.04 0.949 – 1.14 0.413 567 5524 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.922 0.88 – 0.966 0.000576 2184 21550 all phecode
701.3 Circumscribed scleroderma Dermatologic 0.961 0.877 – 1.05 0.392 571 5660 all phecode
701.4 Keloid scar Dermatologic 0.939 0.858 – 1.03 0.17 578 5716 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.01 0.91 – 1.12 0.831 400 3982 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.886 0.861 – 0.911 5.41e-17 6956 29525 all phecode
702.1 Actinic keratosis Dermatologic 0.854 0.825 – 0.885 1.6e-18 4171 26529 all phecode
702.2 Seborrheic keratosis Dermatologic 0.88 0.853 – 0.908 5.17e-16 5480 31552 all phecode
702.4 Degenerative skin disorders Dermatologic 1.13 0.899 – 1.42 0.296 86 832 all phecode
703 Diseases of nail, NOS Dermatologic 1.03 0.976 – 1.09 0.284 1650 14562 all phecode
703.1 Ingrowing nail Dermatologic 1.04 0.964 – 1.11 0.336 920 8597 all phecode
704 Diseases of hair and hair follicles Dermatologic 0.971 0.934 – 1.01 0.135 3118 29542 all phecode
704.1 Alopecia Dermatologic 0.961 0.907 – 1.02 0.182 1408 13871 all phecode
704.11 Alopecia Areata Dermatologic 0.915 0.722 – 1.16 0.466 82 811 all phecode
704.12 Telogen effluvium Dermatologic 0.83 0.63 – 1.09 0.186 63 615 all phecode
704.2 Hirsutism Dermatologic 1.37 1.21 – 1.55 7.84e-07 299 2946 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.966 0.917 – 1.02 0.191 1752 17189 all phecode
705 Disorders of sweat glands Dermatologic 1.21 1.11 – 1.32 2.27e-05 603 6012 all phecode
705.1 Dyshidrosis Dermatologic 1.04 0.866 – 1.24 0.704 154 1540 all phecode
705.3 Hidradenitis Dermatologic 1.4 1.22 – 1.61 1.82e-06 245 2440 all phecode
705.8 Hyperhidrosis Dermatologic 1.01 0.948 – 1.08 0.737 1112 10986 all phecode
706 Diseases of sebaceous glands Dermatologic 0.926 0.9 – 0.953 1.58e-07 5995 39748 all phecode
706.1 Acne Dermatologic 0.866 0.83 – 0.904 4.26e-11 2594 22570 all phecode
706.2 Sebaceous cyst Dermatologic 0.932 0.895 – 0.971 0.000773 2814 26819 all phecode
706.3 Seborrhea Dermatologic 0.898 0.684 – 1.18 0.441 59 582 all phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.981 0.93 – 1.03 0.485 1684 15289 all phecode
707 Chronic ulcer of skin Dermatologic 1.16 1.12 – 1.21 3.39e-13 2871 26816 all phecode
707.1 Decubitus ulcer Dermatologic 1.13 1.05 – 1.22 0.000963 825 8119 all phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.26 1.18 – 1.34 4.32e-12 1108 9992 all phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1.15 1.09 – 1.21 3.41e-07 1641 16172 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.998 0.943 – 1.06 0.949 1477 14427 all phecode
709.2 Sicca syndrome Dermatologic 1.03 0.938 – 1.14 0.508 505 4986 all phecode
709.3 Systemic sclerosis Dermatologic 0.836 0.725 – 0.965 0.0145 224 2209 all phecode
709.5 Dermatomyositis Dermatologic 1.12 0.9 – 1.38 0.318 92 892 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.985 0.781 – 1.24 0.896 90 892 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.02 0.947 – 1.09 0.646 917 9089 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.16 1.09 – 1.24 1.24e-06 1254 12103 all phecode
710.1 Osteomyelitis Musculoskeletal 1.16 1.09 – 1.23 5.27e-06 1203 11636 all phecode
710.11 Acute osteomyelitis Musculoskeletal 1.31 1.19 – 1.43 1.03e-08 590 5708 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.2 1.09 – 1.32 0.000147 531 5163 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.17 1.1 – 1.25 1.47e-06 1153 11149 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.03 0.923 – 1.15 0.604 410 4099 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.12 0.988 – 1.28 0.0768 290 2900 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.24 1.05 – 1.47 0.0107 178 1776 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.24 1.1 – 1.4 0.000544 314 3028 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.33 1.14 – 1.57 0.000397 194 1824 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.14 1.09 – 1.2 7.97e-08 2086 18159 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.17 1.11 – 1.24 9.16e-09 1670 15087 all phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.04 0.808 – 1.33 0.773 77 767 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.14 1.07 – 1.21 6e-05 1209 11967 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.19 1.04 – 1.35 0.0106 262 2611 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.21 1.05 – 1.4 0.00941 219 2182 all phecode
716 Other arthropathies Musculoskeletal 1.11 1.09 – 1.14 1.27e-20 13482 31305 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.16 0.994 – 1.36 0.0597 192 1920 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.946 0.784 – 1.14 0.558 131 1293 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.11 1.09 – 1.14 1.01e-20 13410 31294 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.937 0.82 – 1.07 0.342 261 2565 all phecode
720 Spinal stenosis Musculoskeletal 1.1 1.07 – 1.14 4.39e-08 3958 28539 all phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1.11 1.07 – 1.16 2.73e-07 2872 23656 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1.05 1.02 – 1.09 0.000691 5509 32391 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.05 1.02 – 1.08 0.00295 5153 31896 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.1 1.02 – 1.18 0.014 867 8629 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.22 1.07 – 1.4 0.0027 262 2600 all phecode
722 Intervertebral disc disorders Musculoskeletal 1.08 1.05 – 1.12 2.06e-08 6284 34317 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.07 1.03 – 1.11 0.000154 3591 31411 all phecode
722.3 Schmorl's nodes Musculoskeletal 1.09 0.89 – 1.33 0.416 126 1248 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.07 1.03 – 1.11 0.000241 3957 30744 all phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.11 1.01 – 1.22 0.0348 515 5140 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.06 0.953 – 1.18 0.275 397 3968 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.07 1.02 – 1.13 0.00393 1932 19288 all phecode
723 Other disorders of cervical region Musculoskeletal 0.989 0.923 – 1.06 0.764 952 9495 all phecode
723.1 Torticollis Musculoskeletal 0.961 0.84 – 1.1 0.557 254 2522 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.04 1.01 – 1.08 0.0117 4130 31954 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.05 1 – 1.1 0.0333 2307 21902 all phecode
724.2 Disorders of coccyx Musculoskeletal 0.986 0.887 – 1.1 0.793 426 4215 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.09 1.01 – 1.17 0.0218 931 9295 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.07 1.01 – 1.13 0.0226 1412 14087 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.983 0.96 – 1.01 0.165 9917 30176 all phecode
726.1 Enthesopathy Musculoskeletal 0.976 0.95 – 1 0.0763 7507 30106 all phecode
726.2 Synoviopathy Musculoskeletal 0.964 0.9 – 1.03 0.283 1015 9987 all phecode
726.3 Bursitis Musculoskeletal 0.985 0.936 – 1.04 0.565 1829 16722 all phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 1.01 0.946 – 1.07 0.839 1193 11485 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1 0.974 – 1.03 0.933 7425 30105 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.01 0.974 – 1.05 0.498 3092 24998 all phecode
727.2 Bursitis disorders Musculoskeletal 1 0.899 – 1.11 0.981 419 4112 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.962 0.907 – 1.02 0.185 1400 13621 all phecode
727.5 Rupture of synovium Musculoskeletal 1.13 1.03 – 1.25 0.0142 480 4672 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.968 0.926 – 1.01 0.151 2461 21948 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.987 0.904 – 1.08 0.772 591 5893 all phecode
727.8 Plica syndrome Musculoskeletal 0.896 0.746 – 1.08 0.242 130 1264 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.04 1 – 1.07 0.0403 4546 29473 all phecode
728.1 Muscular calcification and ossification Musculoskeletal 0.928 0.739 – 1.17 0.52 85 843 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.91 0.805 – 1.03 0.134 297 2949 all phecode
728.7 Fasciitis Musculoskeletal 0.984 0.944 – 1.03 0.449 2814 23463 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.806 0.725 – 0.896 6.91e-05 419 4138 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.11 1.07 – 1.15 1.37e-08 3642 27471 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.07 0.838 – 1.37 0.578 74 726 all phecode
729.3 Panniculitis Musculoskeletal 1.21 0.991 – 1.49 0.0612 119 1174 all phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 0.944 0.735 – 1.21 0.653 67 664 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.09 0.94 – 1.26 0.256 210 2091 all phecode
732 Osteochondropathies Musculoskeletal 1.08 0.965 – 1.21 0.18 361 3604 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.19 1.02 – 1.39 0.0269 198 1969 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.913 0.727 – 1.15 0.431 90 882 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.921 0.89 – 0.953 2.15e-06 4543 26941 all phecode
733.2 Cyst of bone Musculoskeletal 0.985 0.845 – 1.15 0.847 190 1900 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.991 0.901 – 1.09 0.848 518 5160 all phecode
733.6 Costochondritis Musculoskeletal 0.998 0.891 – 1.12 0.976 357 3562 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.04 0.965 – 1.12 0.302 822 8205 all phecode
733.9 Chondromalacia Musculoskeletal 0.981 0.792 – 1.21 0.856 96 960 all phecode
735 Acquired foot deformities Musculoskeletal 0.979 0.943 – 1.02 0.256 3417 29622 all phecode
735.1 Flat foot Musculoskeletal 1 0.917 – 1.09 0.992 620 6092 all phecode
735.2 Acquired toe deformities Musculoskeletal 0.977 0.92 – 1.04 0.452 1323 11983 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.997 0.923 – 1.08 0.938 825 7494 all phecode
735.23 Hallux rigidus Musculoskeletal 0.959 0.861 – 1.07 0.442 405 4005 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.958 0.905 – 1.01 0.136 1470 14295 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.99 0.95 – 1.03 0.647 2763 26555 all phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.92 0.743 – 1.14 0.444 104 1033 all phecode
736.2 Acquired deformities of finger Musculoskeletal 0.906 0.782 – 1.05 0.19 215 2142 all phecode
736.3 Acquired deformities of hip Musculoskeletal 1.14 0.853 – 1.51 0.385 60 590 all phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 0.969 0.862 – 1.09 0.598 325 3247 all phecode
736.5 Acquired deformities of knee Musculoskeletal 0.923 0.807 – 1.05 0.239 246 2460 all phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.982 0.874 – 1.1 0.755 339 3365 all phecode
737 Curvature of spine Musculoskeletal 0.947 0.897 – 1 0.0521 1566 15543 all phecode
737.1 Kyphosis (acquired) Musculoskeletal 0.99 0.897 – 1.09 0.844 479 4748 all phecode
737.2 Lordosis (acquired) Musculoskeletal 1.14 0.886 – 1.46 0.312 70 700 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.939 0.882 – 0.999 0.0457 1203 11982 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.01 0.964 – 1.05 0.76 2443 24187 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.12 1.04 – 1.19 0.00141 1057 10542 all phecode
739 Contracture of joint Musculoskeletal 0.95 0.87 – 1.04 0.243 621 6207 all phecode
740 Osteoarthrosis Musculoskeletal 1.12 1.1 – 1.15 5.15e-27 16169 30268 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.09 1.06 – 1.12 1.04e-08 7005 27422 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.08 1.04 – 1.11 2.08e-06 6176 26155 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.1 1.01 – 1.19 0.0256 713 7116 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.06 0.999 – 1.12 0.055 1609 12092 all phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 1.18 1.05 – 1.32 0.00408 373 3586 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.13 1.11 – 1.15 2.49e-28 15497 30141 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.02 0.993 – 1.04 0.172 8555 35884 all phecode
741.1 Ankylosis of joint Musculoskeletal 0.887 0.773 – 1.02 0.0875 245 2445 all phecode
741.2 Stiffness of joint Musculoskeletal 0.955 0.899 – 1.02 0.14 1268 12594 all phecode
741.3 Difficulty in walking Musculoskeletal 1.06 1.02 – 1.11 0.00629 2558 23116 all phecode
741.4 Joint effusions Musculoskeletal 0.992 0.95 – 1.04 0.718 2493 24199 all phecode
741.5 Hemarthrosis Musculoskeletal 1.1 0.888 – 1.37 0.374 94 937 all phecode
741.6 Villonodular synovitis Musculoskeletal 0.903 0.694 – 1.17 0.447 68 666 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.998 0.965 – 1.03 0.887 4404 33771 all phecode
742.1 Loose body in joint Musculoskeletal 1.16 0.976 – 1.37 0.0921 156 1554 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.848 0.748 – 0.962 0.0102 280 2792 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.03 0.896 – 1.18 0.704 245 2450 all phecode
742.9 Other derangement of joint Musculoskeletal 0.998 0.965 – 1.03 0.912 4107 32972 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.941 0.917 – 0.965 1.79e-06 9223 36921 all phecode
743.1 Osteoporosis Musculoskeletal 0.924 0.889 – 0.961 6.39e-05 3712 19477 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.923 0.888 – 0.96 6.07e-05 3657 19276 all phecode
743.12 Senile osteoporosis Musculoskeletal 0.836 0.767 – 0.91 3.67e-05 703 5804 all phecode
743.13 Other specified osteoporosis Musculoskeletal 0.908 0.803 – 1.03 0.124 321 3141 all phecode
743.2 Pathologic fracture Musculoskeletal 0.945 0.885 – 1.01 0.0928 1112 10563 all phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 0.955 0.865 – 1.06 0.369 475 4629 all phecode
743.22 Pathologic fracture of femur Musculoskeletal 0.955 0.795 – 1.15 0.622 143 1391 all phecode
743.4 Stress fracture Musculoskeletal 0.87 0.781 – 0.969 0.0117 407 4046 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.93 0.905 – 0.957 4.4e-07 6970 35237 all phecode
745 Pain in joint Musculoskeletal 0.989 0.97 – 1.01 0.246 19848 26918 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1 0.957 – 1.05 0.923 2236 22256 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.04 0.985 – 1.09 0.169 1767 17598 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.988 0.908 – 1.07 0.769 650 6497 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.09 1.01 – 1.18 0.029 751 7480 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.04 0.939 – 1.16 0.426 410 4090 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.91 0.828 – 1 0.0523 501 5010 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.01 0.824 – 1.23 0.959 111 1110 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.905 0.827 – 0.992 0.0321 555 5549 all phecode
749.1 Cleft palate Congenital Anomalies 0.79 0.638 – 0.978 0.0307 97 970 all phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.966 0.785 – 1.19 0.744 105 1041 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.974 0.907 – 1.05 0.478 893 8919 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.952 0.852 – 1.06 0.379 366 3655 all phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 1.05 0.866 – 1.28 0.617 119 1185 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.871 0.702 – 1.08 0.21 99 982 all phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 0.981 0.819 – 1.17 0.83 134 1332 all phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 0.995 0.753 – 1.31 0.97 60 593 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.993 0.903 – 1.09 0.877 531 5300 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.941 0.833 – 1.06 0.325 313 3129 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.07 0.924 – 1.24 0.365 222 2214 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.988 0.942 – 1.04 0.633 2008 19975 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.978 0.894 – 1.07 0.621 574 5740 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.01 0.907 – 1.13 0.841 384 3840 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.941 0.795 – 1.11 0.476 153 1527 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.994 0.938 – 1.05 0.851 1379 13704 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.977 0.912 – 1.05 0.515 976 9685 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.967 0.854 – 1.1 0.604 294 2927 all phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 0.996 0.85 – 1.17 0.961 182 1809 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.13 1.06 – 1.21 0.000115 1133 11313 all phecode
752.1 Neural tube defects Congenital Anomalies 1.14 1.07 – 1.23 0.000167 923 9209 all phecode
752.11 Spina bifida Congenital Anomalies 1.06 0.906 – 1.24 0.465 176 1760 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.07 0.934 – 1.23 0.315 232 2320 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.01 0.863 – 1.18 0.907 207 2051 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.88 0.657 – 1.18 0.391 58 580 all phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 1.12 0.836 – 1.51 0.444 56 546 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.09 1.03 – 1.16 0.00495 1216 12116 all phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 1.08 0.897 – 1.31 0.411 135 1333 all phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 1.12 1.02 – 1.23 0.0156 558 5570 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.03 0.952 – 1.12 0.455 747 7458 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.03 0.921 – 1.15 0.629 368 3663 all phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 1.05 0.822 – 1.35 0.684 74 740 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.02 0.903 – 1.15 0.779 321 3205 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.02 0.868 – 1.19 0.846 185 1847 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.953 0.899 – 1.01 0.107 1358 13579 all phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.958 0.742 – 1.24 0.745 68 680 all phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 1.04 0.812 – 1.34 0.733 71 694 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.912 0.812 – 1.02 0.121 335 3346 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.963 0.901 – 1.03 0.28 1003 10014 all phecode
757 Congenital anomalies of the integument Congenital Anomalies 0.872 0.783 – 0.97 0.0116 401 4001 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.882 0.754 – 1.03 0.115 185 1845 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.9 0.75 – 1.08 0.254 135 1349 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.951 0.869 – 1.04 0.276 557 5566 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.884 0.688 – 1.14 0.336 71 710 all phecode
760 Back pain Symptoms 1.06 1.04 – 1.08 4.06e-09 16037 30719 all phecode
761 Cervicalgia Symptoms 1.01 0.981 – 1.04 0.535 6528 39755 all phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 1.04 1 – 1.08 0.0316 3657 32599 all phecode
764 Sciatica Symptoms 1.08 1.04 – 1.12 1.79e-05 3542 32015 all phecode
765 Cervical radiculitis Symptoms 1.02 0.969 – 1.07 0.451 1799 17851 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.06 1.02 – 1.09 0.000582 5124 37132 all phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 0.996 0.823 – 1.2 0.964 117 1168 all phecode
769 Nonallopathic lesions NEC Symptoms 1 0.94 – 1.07 0.922 1131 11220 all phecode
770 Myalgia and myositis unspecified Symptoms 1.07 1.04 – 1.1 1.48e-05 5533 34303 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.07 1.03 – 1.1 8.26e-05 4799 35575 all phecode
771.1 Swelling of limb Symptoms 1.13 1.09 – 1.16 5.76e-15 5743 35539 all phecode
771.2 Cramp of limb Symptoms 1.06 0.993 – 1.13 0.0804 1079 10568 all phecode
772 Symptoms of the muscles Symptoms 0.927 0.884 – 0.973 0.002 2042 20221 all phecode
772.1 Muscular wasting and disuse atrophy Symptoms 0.902 0.811 – 1 0.056 422 4199 all phecode
772.2 Spasm of muscle Symptoms 1.01 0.962 – 1.05 0.771 2299 22726 all phecode
772.3 Muscle weakness Symptoms 1.07 1.03 – 1.12 0.000632 2949 28064 all phecode
772.4 Rhabdomyolysis Symptoms 1.02 0.856 – 1.21 0.855 159 1572 all phecode
772.6 Facial weakness Symptoms 0.985 0.892 – 1.09 0.765 478 4742 all phecode
780 Hypothermia/Chills Symptoms 1.04 0.939 – 1.15 0.454 453 4514 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.04 0.995 – 1.08 0.0897 2822 26225 all phecode
781.1 Loss of height Symptoms 0.967 0.799 – 1.17 0.731 130 1269 all phecode
781.2 Abnormal posture Symptoms 1.02 0.771 – 1.34 0.909 57 567 all phecode
782.3 Edema Symptoms 1.16 1.12 – 1.19 1.52e-22 5874 36788 all phecode
782.6 Pallor and flushing Symptoms 0.949 0.883 – 1.02 0.15 927 9252 all phecode
783 Fever of unknown origin Symptoms 1.06 1.03 – 1.09 3.85e-05 5733 40720 all phecode
783.1 Postprocedural fever Symptoms 1.08 0.953 – 1.22 0.233 300 2992 all phecode
785 Abdominal pain Symptoms 1.04 1.02 – 1.06 0.000424 16458 30297 all phecode
788 Syncope and collapse Symptoms 1.02 0.981 – 1.05 0.393 3851 35832 all phecode
789 Nausea and vomiting Symptoms 1.05 1.03 – 1.07 3.06e-05 10568 36098 all phecode
789.1 Persistent vomiting Symptoms 1.17 1.09 – 1.27 3.87e-05 798 7924 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.05 1.01 – 1.1 0.0247 2363 22690 all phecode
790.1 Elevated sedimentation rate Symptoms 1.12 0.974 – 1.3 0.11 236 2322 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.06 1.04 – 1.09 3.62e-06 7539 37788 all phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.15 1.01 – 1.3 0.0301 309 3075 all phecode
790.9 Abnormal arterial blood gases Symptoms 1.2 1 – 1.43 0.0491 155 1521 all phecode
791 Gangrene Symptoms 1.09 0.964 – 1.23 0.17 313 3115 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 0.987 0.946 – 1.03 0.551 2820 14872 all phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 1.01 0.942 – 1.07 0.868 1100 9861 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.981 0.892 – 1.08 0.691 515 5133 all phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 0.995 0.95 – 1.04 0.829 2182 20242 all phecode
795.8 Abnormal tumor markers Symptoms 0.925 0.878 – 0.974 0.00297 1745 15551 all phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 1.17 0.904 – 1.52 0.23 61 605 all phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 0.917 0.788 – 1.07 0.265 201 2000 all phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.869 0.827 – 0.914 4.17e-08 2125 9930 all phecode
797 Shock Symptoms 1.04 0.957 – 1.14 0.326 605 6050 all phecode
797.1 Cardiogenic shock Symptoms 1.14 0.994 – 1.31 0.0608 242 2420 all phecode
798 Malaise and fatigue Symptoms 1.01 0.991 – 1.04 0.233 11539 35196 all phecode
798.1 Chronic fatigue syndrome Symptoms 1.01 0.958 – 1.06 0.754 1823 17795 all phecode
800 Fracture of lower limb Injuries & Poisonings 1.01 0.967 – 1.06 0.636 2344 22951 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.987 0.895 – 1.09 0.783 512 4961 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.96 0.883 – 1.04 0.344 670 6582 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.08 1 – 1.16 0.0391 898 8966 all phecode
800.4 Fracture of patella Injuries & Poisonings 1.02 0.907 – 1.14 0.752 346 3456 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.02 0.977 – 1.07 0.35 2358 22645 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.05 0.983 – 1.12 0.147 1120 11178 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.948 0.848 – 1.06 0.343 380 3765 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.948 0.903 – 0.994 0.0266 2051 20360 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.01 0.93 – 1.09 0.866 734 7322 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.948 0.889 – 1.01 0.104 1112 11075 all phecode
803.21 Colles' fracture Injuries & Poisonings 0.897 0.79 – 1.02 0.0925 291 2904 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.869 0.791 – 0.955 0.00343 514 5140 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.937 0.889 – 0.988 0.0165 1628 16042 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.02 0.961 – 1.08 0.514 1336 13242 all phecode
807 Fracture of ribs Injuries & Poisonings 0.961 0.886 – 1.04 0.336 683 6815 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.975 0.937 – 1.01 0.208 2941 28633 all phecode
816 Cerebral laceration and contusion Injuries & Poisonings 1.27 0.95 – 1.71 0.106 54 531 all phecode
817 Concussion Injuries & Poisonings 1.01 0.942 – 1.08 0.843 1018 10149 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.904 0.801 – 1.02 0.105 311 3104 all phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.875 0.7 – 1.09 0.239 90 895 all phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 0.989 0.79 – 1.24 0.92 97 970 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.979 0.936 – 1.02 0.349 2287 22671 all phecode
830 Dislocation Injuries & Poisonings 0.953 0.92 – 0.987 0.0067 3862 34720 all phecode
835 Internal derangement of knee Injuries & Poisonings 0.984 0.94 – 1.03 0.503 2231 21628 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.06 0.96 – 1.16 0.259 496 4954 all phecode
840 Sprains and strains Injuries & Poisonings 0.969 0.945 – 0.994 0.0171 7838 37998 all phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 1.01 0.922 – 1.11 0.81 537 5356 all phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.994 0.942 – 1.05 0.827 1640 16263 all phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.942 0.904 – 0.981 0.00366 2875 24879 all phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.981 0.929 – 1.04 0.486 1583 15592 all phecode
842 Other sprains and strains Injuries & Poisonings 0.979 0.925 – 1.04 0.479 1407 13924 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.06 1.01 – 1.11 0.0122 2072 20649 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.14 1.09 – 1.18 1.76e-10 2982 27545 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.04 0.941 – 1.15 0.437 460 4600 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.14 1.09 – 1.2 5.83e-08 1985 19675 all phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.04 0.909 – 1.18 0.584 264 2640 all phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.04 0.914 – 1.18 0.563 293 2929 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.09 1.03 – 1.16 0.00458 1310 13087 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.07 1.03 – 1.12 0.00229 2213 21944 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.06 1.01 – 1.11 0.0112 2110 21070 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1.07 0.906 – 1.27 0.416 166 1660 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.04 1.01 – 1.08 0.0129 4117 36734 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.974 0.837 – 1.13 0.731 204 2026 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.976 0.817 – 1.17 0.788 144 1437 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.909 0.857 – 0.964 0.00149 1346 13301 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.973 0.839 – 1.13 0.716 207 2057 all phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 0.951 0.833 – 1.08 0.453 275 2724 all phecode
870.6 Open wound of neck Injuries & Poisonings 1 0.864 – 1.16 0.998 214 2128 all phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.28 1.07 – 1.53 0.00599 144 1440 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.04 1 – 1.08 0.0267 3530 32903 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.986 0.9 – 1.08 0.755 572 5701 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.945 0.882 – 1.01 0.108 984 9772 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.28 1.16 – 1.41 5.24e-07 490 4843 all phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.17 1.03 – 1.33 0.0147 295 2921 all phecode
872 Traumatic amputation Injuries & Poisonings 1.13 1.03 – 1.24 0.0106 551 5477 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.22 1.03 – 1.43 0.0186 170 1697 all phecode
875 Non-healing surgical wound Injuries & Poisonings 1.16 1.06 – 1.27 0.00133 572 5720 all phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.22 1.13 – 1.31 3.63e-07 802 8003 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.03 0.964 – 1.1 0.362 1010 10096 all phecode
910 Superficial injury, infected Injuries & Poisonings 0.891 0.734 – 1.08 0.245 119 1161 all phecode
911 Blister Injuries & Poisonings 1.21 1.07 – 1.37 0.00229 302 2996 all phecode
912 Insect bite Injuries & Poisonings 1.01 0.913 – 1.11 0.9 492 4886 all phecode
913 Toxic effect of venom Injuries & Poisonings 0.822 0.73 – 0.927 0.00133 337 3326 all phecode
916 Contusion Injuries & Poisonings 1.03 1 – 1.07 0.0463 4296 38033 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.985 0.912 – 1.06 0.707 763 7596 all phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.925 0.853 – 1 0.058 714 7072 all phecode
938 Dermatitis due to solar radiation Dermatologic 0.9 0.873 – 0.929 2.35e-11 5567 29098 all phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.944 0.815 – 1.09 0.445 217 2164 all phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.894 0.866 – 0.922 2.29e-12 5307 28656 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.993 0.966 – 1.02 0.644 6704 32389 all phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 0.949 0.755 – 1.19 0.655 91 870 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.01 0.868 – 1.19 0.859 188 1880 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.08 0.948 – 1.24 0.241 269 2688 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.95 0.862 – 1.05 0.297 500 4940 all phecode
947 Urticaria Dermatologic 1 0.941 – 1.07 0.942 1177 11454 all phecode
949 Allergies, other Injuries & Poisonings 1.02 0.99 – 1.05 0.217 7251 32350 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.11 1 – 1.22 0.0418 494 4940 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.927 0.773 – 1.11 0.413 136 1352 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.03 0.97 – 1.1 0.326 1217 12158 all phecode
958.1 Postoperative shock Injuries & Poisonings 0.964 0.817 – 1.14 0.659 169 1688 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.02 0.829 – 1.24 0.883 114 1140 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.12 1.07 – 1.17 8.69e-07 2479 22087 all phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 1.17 1.04 – 1.32 0.00957 342 3403 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.12 1.06 – 1.18 5.42e-05 1636 16005 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.09 0.992 – 1.19 0.0724 528 5234 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.1 1.03 – 1.18 0.00357 1065 10347 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.08 0.999 – 1.17 0.0522 803 7976 all phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.1 0.985 – 1.23 0.0903 379 3782 all phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 1.24 0.944 – 1.63 0.122 62 612 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.08 0.975 – 1.19 0.144 478 4773 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.03 0.982 – 1.07 0.256 2533 24531 all phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.03 0.983 – 1.07 0.232 2469 24057 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.06 0.98 – 1.15 0.141 743 7337 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.07 0.983 – 1.16 0.12 712 7027 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.04 0.967 – 1.12 0.278 864 8601 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.16 1.1 – 1.23 1.94e-07 1469 14402 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.02 0.836 – 1.24 0.856 119 1182 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.997 0.807 – 1.23 0.975 103 1006 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.98 0.922 – 1.04 0.52 1254 12464 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.15 1.01 – 1.31 0.0289 281 2797 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.25 0.966 – 1.61 0.0903 67 643 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.15 1.01 – 1.3 0.0348 288 2858 all phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 1.2 0.951 – 1.51 0.125 80 776 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.17 0.957 – 1.43 0.126 104 1034 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.05 0.858 – 1.28 0.655 113 1130 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.16 0.914 – 1.47 0.222 81 810 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.13 0.881 – 1.45 0.336 71 703 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.1 1.04 – 1.16 0.000341 1763 16599 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.04 1 – 1.08 0.0464 3448 30885 all phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 0.996 0.94 – 1.06 0.882 1391 13877 all phecode
985 Toxic effect of other metals Injuries & Poisonings 1.2 0.905 – 1.58 0.208 57 564 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.02 0.849 – 1.24 0.798 129 1275 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.03 0.995 – 1.07 0.0906 3927 31223 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.12 1.07 – 1.17 1.47e-06 2192 21710 all phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.16 1.02 – 1.31 0.0246 291 2910 all phecode
994.2 Sepsis Injuries & Poisonings 1.11 1.06 – 1.16 1.41e-05 2086 20666 all phecode
994.21 Septic shock Injuries & Poisonings 1.12 1.03 – 1.22 0.00816 627 6260 all phecode
008 Intestinal infection Infectious Diseases 1.05 0.972 – 1.14 0.212 745 6950 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.26 1.11 – 1.42 0.000278 321 2987 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.24 1.08 – 1.43 0.00216 251 2331 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.09 0.921 – 1.28 0.325 168 1792 exclusion phecode
010 Tuberculosis Infectious Diseases 0.962 0.736 – 1.26 0.775 61 539 exclusion phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.957 0.645 – 1.42 0.827 27 197 exclusion phecode
038 Septicemia Infectious Diseases 1.25 1.14 – 1.37 3.48e-06 551 5136 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.29 1.05 – 1.57 0.0132 115 1172 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.19 0.876 – 1.6 0.271 50 455 exclusion phecode
038.3 Bacteremia Infectious Diseases 1.26 1.1 – 1.43 0.000838 266 2396 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.11 1.05 – 1.18 0.000424 1319 9006 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.26 1.12 – 1.41 7.27e-05 349 3617 exclusion phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.36 1.16 – 1.6 0.00014 181 1916 exclusion phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.3 1.1 – 1.54 0.00224 157 1700 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.21 1.08 – 1.35 0.000914 381 3462 exclusion phecode
041.21 Rheumatic fever / chorea Infectious Diseases 1.11 0.812 – 1.51 0.517 50 554 exclusion phecode
041.4 E. coli Infectious Diseases 1.18 1.03 – 1.35 0.0208 260 2614 exclusion phecode
041.8 H. pylori Infectious Diseases 0.956 0.719 – 1.27 0.756 58 595 exclusion phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.28 1.03 – 1.61 0.0279 96 849 exclusion phecode
053 Herpes zoster Infectious Diseases 0.931 0.831 – 1.04 0.211 369 3324 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.11 0.814 – 1.51 0.511 50 459 exclusion phecode
054 Herpes simplex Infectious Diseases 0.991 0.892 – 1.1 0.866 422 3794 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.16 0.984 – 1.36 0.0769 193 1614 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.89 0.93 – 3.85 0.0783 11 160 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 1.21 0.886 – 1.65 0.232 52 441 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.25 1.03 – 1.51 0.0224 129 966 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.27 0.935 – 1.74 0.125 53 395 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.15 1 – 1.32 0.0479 245 2187 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.63 1.21 – 2.19 0.00121 59 289 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.66 1.22 – 2.26 0.00135 50 218 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.903 0.84 – 0.971 0.00603 911 7141 exclusion phecode
079 Viral infection Infectious Diseases 0.999 0.946 – 1.06 0.982 1707 8160 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.916 0.854 – 0.983 0.0154 975 7161 exclusion phecode
079.2 Infectious mononucleosis Infectious Diseases 0.851 0.689 – 1.05 0.136 106 885 exclusion phecode
079.9 Viremia, NOS Infectious Diseases 1.27 1.09 – 1.47 0.00181 214 2028 exclusion phecode
080 Postoperative infection Infectious Diseases 1.13 1.03 – 1.24 0.00806 540 5845 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.23 1.11 – 1.38 0.000169 389 3473 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.07 0.945 – 1.22 0.279 277 2444 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.99 0.909 – 1.08 0.817 644 6718 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.98 0.895 – 1.07 0.669 555 6022 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.976 0.868 – 1.1 0.68 340 3534 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.04 0.865 – 1.26 0.648 129 1645 exclusion phecode
110.13 Dermatophytosis of the body Infectious Diseases 0.909 0.755 – 1.1 0.316 131 1711 exclusion phecode
110.2 Dermatomycoses Infectious Diseases 1.11 0.896 – 1.38 0.334 103 952 exclusion phecode
112 Candidiasis Infectious Diseases 1.15 1.06 – 1.23 0.000282 876 7564 exclusion phecode
112.3 Candidiasis of skin and nails Infectious Diseases 0.964 0.737 – 1.26 0.789 57 1616 exclusion phecode
117 Mycoses Infectious Diseases 1.17 0.987 – 1.39 0.0706 164 1439 exclusion phecode
117.1 Histoplasmosis Infectious Diseases 1.25 0.807 – 1.94 0.316 23 193 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.4 1.04 – 1.89 0.0261 49 340 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.945 0.698 – 1.28 0.713 48 434 exclusion phecode
130.1 Lyme disease Infectious Diseases 0.974 0.698 – 1.36 0.877 38 309 exclusion phecode
131 Protozoan infection Infectious Diseases 1.68 0.937 – 3.02 0.0814 11 163 exclusion phecode
132 Infestation (lice, mites) Infectious Diseases 1.23 0.915 – 1.67 0.168 46 468 exclusion phecode
134 Helminthiases Infectious Diseases 1.16 0.733 – 1.83 0.532 22 177 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.38 0.757 – 2.52 0.292 16 108 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.15 1.07 – 1.24 0.000158 854 7457 exclusion phecode
145 Cancer of mouth Neoplasms 1.32 1.18 – 1.47 7.83e-07 402 2723 exclusion phecode
145.1 Cancer of lip Neoplasms 1.57 0.941 – 2.62 0.084 16 137 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.35 1.15 – 1.6 0.000279 186 1121 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.925 0.726 – 1.18 0.528 79 717 exclusion phecode
145.4 Cancer of the gums Neoplasms 1.82 1.31 – 2.53 0.000371 54 343 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.56 1.2 – 2.04 0.00104 75 363 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.31 1.17 – 1.47 6.26e-06 355 2312 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.81 1.41 – 2.31 2.37e-06 105 568 exclusion phecode
149.2 Cancer of nasopharynx Neoplasms 1.36 0.903 – 2.04 0.141 33 211 exclusion phecode
149.3 Cancer of hypopharynx Neoplasms 1.36 0.913 – 2.04 0.129 28 154 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.34 1.09 – 1.65 0.00581 102 636 exclusion phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 1.45 1.21 – 1.74 6.05e-05 148 971 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.07 0.796 – 1.43 0.661 60 466 exclusion phecode
150 Cancer of esophagus Neoplasms 1.59 1.28 – 1.98 3.09e-05 99 751 exclusion phecode
151 Cancer of stomach Neoplasms 1.13 0.918 – 1.39 0.251 112 884 exclusion phecode
153 Colorectal cancer Neoplasms 1.06 0.939 – 1.2 0.337 307 2977 exclusion phecode
153.2 Colon cancer Neoplasms 1.08 0.939 – 1.25 0.269 224 2327 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.02 0.874 – 1.2 0.77 194 1749 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.22 0.986 – 1.51 0.0678 109 958 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.16 0.896 – 1.5 0.259 72 634 exclusion phecode
157 Pancreatic cancer Neoplasms 1.17 0.953 – 1.44 0.133 119 943 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.03 0.922 – 1.16 0.56 366 3192 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.14 1.02 – 1.27 0.0212 398 3485 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.925 0.67 – 1.28 0.635 44 428 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.24 0.876 – 1.76 0.225 44 300 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.19 0.918 – 1.54 0.189 74 624 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.968 0.665 – 1.41 0.864 36 255 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.12 0.992 – 1.26 0.0677 327 2562 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.06 0.925 – 1.21 0.405 254 2026 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 1.12 1.01 – 1.25 0.0277 438 3720 exclusion phecode
170.1 Bone cancer Neoplasms 1.26 1.08 – 1.46 0.00294 205 1645 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1.07 0.948 – 1.22 0.261 295 2650 exclusion phecode
172 Skin cancer Neoplasms 0.957 0.907 – 1.01 0.11 2005 7136 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.898 0.84 – 0.959 0.00147 1183 6208 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.87 0.797 – 0.949 0.00161 622 5040 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.959 0.905 – 1.02 0.162 1698 6245 exclusion phecode
172.21 Basal cell carcinoma Neoplasms 0.881 0.817 – 0.951 0.00112 900 4642 exclusion phecode
172.22 Squamous cell carcinoma Neoplasms 1.04 0.945 – 1.14 0.452 583 3196 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.817 0.727 – 0.919 0.000739 363 2293 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.909 0.823 – 1 0.0607 472 3913 exclusion phecode
174 Breast cancer Neoplasms 0.925 0.858 – 0.997 0.0423 942 4018 exclusion phecode
174.1 Breast cancer [female] Neoplasms 0.926 0.857 – 1 0.051 905 3840 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.927 0.857 – 1 0.0543 886 3818 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.677 0.513 – 0.894 0.00597 65 592 exclusion phecode
175 Acquired absence of breast Neoplasms 0.884 0.779 – 1 0.0564 301 2272 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.06 0.953 – 1.17 0.298 442 3333 exclusion phecode
180.1 Cervical cancer Neoplasms 1.17 0.974 – 1.41 0.0934 135 1295 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.01 0.898 – 1.13 0.882 356 2584 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.963 0.785 – 1.18 0.721 105 1877 exclusion phecode
184 Cancer of other female genital organs Neoplasms 0.992 0.876 – 1.12 0.897 313 2979 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.924 0.771 – 1.11 0.386 151 1504 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.895 0.731 – 1.1 0.282 120 1139 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.08 0.905 – 1.3 0.381 150 1531 exclusion phecode
185 Cancer of prostate Neoplasms 0.894 0.791 – 1.01 0.0741 399 1589 exclusion phecode
187 Cancer of other male genital organs Neoplasms 0.951 0.724 – 1.25 0.715 66 631 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.02 0.573 – 1.81 0.95 14 181 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.8 0.579 – 1.11 0.177 42 389 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.52 0.779 – 2.96 0.22 12 97 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.08 0.981 – 1.19 0.117 474 4570 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.12 0.971 – 1.3 0.119 217 2783 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.11 0.945 – 1.3 0.207 179 2436 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.48 1.04 – 2.12 0.0313 43 421 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.1 0.968 – 1.24 0.149 307 2791 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.14 1 – 1.3 0.0433 290 2565 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.29 1.06 – 1.58 0.0127 116 1178 exclusion phecode
190 Cancer of eye Neoplasms 0.989 0.692 – 1.41 0.953 44 274 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.02 0.896 – 1.17 0.744 257 2389 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.962 0.824 – 1.12 0.619 189 1564 exclusion phecode
191.11 Cancer of brain Neoplasms 1 0.848 – 1.18 0.983 166 1311 exclusion phecode
193 Thyroid cancer Neoplasms 0.984 0.839 – 1.15 0.838 180 2295 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.04 0.853 – 1.27 0.682 115 1361 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.02 0.978 – 1.07 0.309 3803 6337 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.02 0.974 – 1.07 0.407 3739 6336 exclusion phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1.31 1.14 – 1.49 7.87e-05 276 1686 exclusion phecode
196 Radiotherapy Neoplasms 1 0.912 – 1.1 0.949 560 3437 exclusion phecode
197 Chemotherapy Neoplasms 1.1 1.03 – 1.17 0.00699 1227 5333 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.11 1.04 – 1.18 0.00275 1285 5236 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.09 1.01 – 1.18 0.0254 840 4617 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.21 1.04 – 1.4 0.0125 218 1968 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.08 0.931 – 1.26 0.303 220 1681 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.11 0.944 – 1.31 0.203 193 1429 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.17 0.984 – 1.4 0.0757 154 1229 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.33 1.13 – 1.56 0.000501 188 1540 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.15 0.898 – 1.49 0.262 81 608 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.03 0.968 – 1.11 0.32 1222 6068 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.48 0.993 – 2.21 0.0543 30 219 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.19 1.04 – 1.36 0.00958 259 2376 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.16 0.847 – 1.6 0.348 43 384 exclusion phecode
201 Hodgkin's disease Neoplasms 1.26 0.945 – 1.69 0.115 47 409 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.13 1.01 – 1.26 0.0301 375 3286 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.12 0.993 – 1.26 0.0652 318 2810 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.07 0.906 – 1.25 0.443 183 1510 exclusion phecode
202.22 Reticulosarcoma Neoplasms 0.94 0.658 – 1.34 0.733 36 352 exclusion phecode
202.24 Large cell lymphoma Neoplasms 0.974 0.68 – 1.39 0.886 38 319 exclusion phecode
204 Leukemia Neoplasms 1.04 0.88 – 1.24 0.62 153 1343 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1.06 0.796 – 1.42 0.68 58 448 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.16 0.735 – 1.82 0.53 21 173 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.95 0.667 – 1.35 0.774 38 313 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.08 0.83 – 1.41 0.566 62 505 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.896 0.617 – 1.3 0.563 36 268 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.05 0.629 – 1.75 0.851 16 128 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.18 0.854 – 1.63 0.317 42 438 exclusion phecode
208 Benign neoplasm of colon Neoplasms 0.997 0.947 – 1.05 0.895 2119 8346 exclusion phecode
209 Neuroendocrine tumors Neoplasms 1.07 0.779 – 1.48 0.661 41 515 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.06 0.959 – 1.17 0.257 499 4205 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.08 1.02 – 1.14 0.0113 1559 8697 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.14 1.03 – 1.27 0.01 437 3952 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1 0.899 – 1.11 0.994 415 3699 exclusion phecode
214 Lipoma Neoplasms 1.02 0.894 – 1.17 0.747 260 3192 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.963 0.812 – 1.14 0.663 160 2008 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.999 0.933 – 1.07 0.97 1012 9144 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.911 0.871 – 0.954 6.13e-05 2817 8094 exclusion phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 1.31 0.931 – 1.84 0.122 45 416 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.845 0.766 – 0.932 0.000781 502 3752 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.839 0.757 – 0.929 0.000763 464 3438 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.92 0.86 – 0.985 0.0172 1154 4797 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.851 0.768 – 0.942 0.00195 461 4411 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.93 0.864 – 1 0.0547 944 4715 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.894 0.775 – 1.03 0.123 226 2392 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.967 0.878 – 1.07 0.497 506 4088 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.761 0.649 – 0.893 0.000818 182 1720 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.08 0.955 – 1.22 0.223 326 2723 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.873 0.735 – 1.04 0.123 161 1399 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.895 0.742 – 1.08 0.247 134 1127 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.07 0.939 – 1.21 0.316 275 2764 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.995 0.861 – 1.15 0.951 213 2174 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.27 0.988 – 1.64 0.0619 71 639 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.02 0.898 – 1.17 0.728 259 3226 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.02 0.899 – 1.16 0.76 283 3878 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.08 0.827 – 1.4 0.587 63 965 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.974 0.822 – 1.15 0.759 157 1863 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.959 0.739 – 1.24 0.752 63 1012 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.823 0.748 – 0.905 5.66e-05 538 4535 exclusion phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.758 0.674 – 0.853 4.13e-06 355 2832 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.973 0.921 – 1.03 0.331 1669 8554 exclusion phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.97 0.911 – 1.03 0.35 1210 7778 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.08 0.932 – 1.24 0.32 219 2530 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.05 0.96 – 1.15 0.293 605 5567 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.02 0.923 – 1.13 0.703 475 4945 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.06 0.926 – 1.22 0.383 236 3181 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.01 0.897 – 1.15 0.816 299 3335 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.857 0.703 – 1.05 0.128 118 1249 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.15 0.708 – 1.86 0.579 19 307 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.883 0.687 – 1.14 0.332 72 698 exclusion phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.905 0.638 – 1.28 0.574 38 356 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.04 0.985 – 1.11 0.15 1647 7677 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.94 0.84 – 1.05 0.288 351 4262 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.11 0.977 – 1.26 0.109 284 3037 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.05 0.987 – 1.11 0.129 1538 7562 exclusion phecode
245 Thyroiditis Endocrine/metabolic 1.28 1.09 – 1.5 0.0028 178 2110 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.36 1.14 – 1.64 0.00086 138 1770 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.36 1.14 – 1.63 0.000888 137 1751 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.03 0.968 – 1.1 0.331 1301 7120 exclusion phecode
246.2 Thyroid cyst Endocrine/metabolic 0.824 0.539 – 1.26 0.369 25 228 exclusion phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1.05 0.91 – 1.22 0.483 218 2156 exclusion phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.12 0.929 – 1.36 0.23 169 1894 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.11 1.05 – 1.18 0.000565 1798 8752 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.23 1.06 – 1.43 0.00659 469 2920 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.91 1.31 – 2.8 0.000837 103 226 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.25 0.982 – 1.59 0.0699 154 616 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.43 1.11 – 1.84 0.00562 189 705 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.58 1.23 – 2.04 0.000397 160 588 exclusion phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 1.39 0.948 – 2.03 0.092 49 173 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.14 1.06 – 1.23 0.000757 1078 7827 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.77 1.19 – 2.64 0.00495 77 288 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.47 1.23 – 1.77 3.35e-05 173 3130 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.29 1.06 – 1.57 0.00961 207 2284 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.3 1.09 – 1.56 0.00364 215 3893 exclusion phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.21 0.932 – 1.57 0.154 71 1331 exclusion phecode
250.3 Insulin pump user Endocrine/metabolic 1.29 1.13 – 1.48 0.000229 438 5081 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.09 1.01 – 1.17 0.0193 1238 8248 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.04 0.892 – 1.2 0.64 232 4125 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.1 1.02 – 1.19 0.00979 1125 7996 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.88 1.16 – 3.04 0.0105 26 290 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.34 1.11 – 1.63 0.00267 205 3102 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.21 1.04 – 1.4 0.013 256 2093 exclusion phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.06 0.924 – 1.22 0.404 245 1974 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.12 0.972 – 1.3 0.114 310 2348 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.05 0.95 – 1.16 0.34 477 5165 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.05 0.944 – 1.16 0.381 435 4715 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.16 0.933 – 1.45 0.178 98 1179 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.06 0.899 – 1.25 0.485 164 1895 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.08 0.791 – 1.47 0.637 48 670 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.892 0.502 – 1.59 0.698 11 203 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.975 0.69 – 1.38 0.884 32 477 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.32 0.809 – 2.16 0.266 15 182 exclusion phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 0.983 0.598 – 1.62 0.946 18 220 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.06 0.716 – 1.56 0.784 30 242 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.14 1 – 1.29 0.0461 276 3379 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.02 0.78 – 1.34 0.866 56 924 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.796 0.533 – 1.19 0.266 26 495 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.13 0.683 – 1.87 0.633 15 281 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.22 1.01 – 1.48 0.0365 131 1432 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.24 1.02 – 1.5 0.0285 123 1361 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.925 0.806 – 1.06 0.268 237 3240 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.799 0.632 – 1.01 0.0611 78 2257 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1.05 0.874 – 1.26 0.596 127 1530 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.07 0.884 – 1.29 0.495 122 1469 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.48 0.881 – 2.48 0.138 17 186 exclusion phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.945 0.64 – 1.39 0.776 31 330 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 1 0.86 – 1.16 0.997 201 2439 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.27 1.19 – 1.37 2.67e-11 988 5553 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.48 1.2 – 1.82 0.000194 147 559 exclusion phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.42 1.3 – 1.56 8.7e-14 600 3325 exclusion phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.45 1.24 – 1.7 3.25e-06 214 1201 exclusion phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.43 1.22 – 1.67 1.33e-05 210 1199 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.2 1.05 – 1.37 0.00773 264 1878 exclusion phecode
260.7 Polyphagia Endocrine/metabolic 0.76 0.437 – 1.32 0.332 16 167 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.11 1.05 – 1.18 0.000229 1599 8182 exclusion phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1.43 0.907 – 2.24 0.125 22 160 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.24 1.06 – 1.47 0.00933 175 1833 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.11 1.05 – 1.18 0.000379 1500 8199 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.909 0.546 – 1.51 0.714 14 118 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.16 1.01 – 1.33 0.0297 269 2874 exclusion phecode
263 Other nutritional deficiency Endocrine/metabolic 1.21 1.08 – 1.35 0.00119 368 3637 exclusion phecode
264 Lack of normal physiological development Endocrine/metabolic 1.04 0.832 – 1.3 0.739 103 699 exclusion phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1 0.736 – 1.37 0.988 51 309 exclusion phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 1.06 0.749 – 1.49 0.756 38 286 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.32 1.16 – 1.5 2.04e-05 286 3036 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.17 1.01 – 1.36 0.0397 201 2098 exclusion phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 1.07 0.756 – 1.52 0.695 34 418 exclusion phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.98 0.672 – 1.43 0.917 29 348 exclusion phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 1.09 0.622 – 1.92 0.758 10 223 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.2 1.01 – 1.42 0.0367 164 1518 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.14 0.886 – 1.47 0.306 72 737 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 0.672 0.398 – 1.14 0.138 19 142 exclusion phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 0.817 0.467 – 1.43 0.479 18 134 exclusion phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.35 1.04 – 1.74 0.0217 76 663 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.01 0.909 – 1.12 0.865 417 6296 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.01 0.904 – 1.12 0.904 394 6130 exclusion phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.14 0.759 – 1.73 0.52 26 230 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.02 0.972 – 1.07 0.392 2862 7532 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.02 0.973 – 1.07 0.386 2851 7518 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.01 0.931 – 1.09 0.891 885 5677 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.04 0.855 – 1.26 0.709 112 2933 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.02 0.914 – 1.14 0.738 426 4669 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.06 0.797 – 1.4 0.706 61 737 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.18 1.03 – 1.34 0.0131 266 4357 exclusion phecode
274.1 Gout Endocrine/metabolic 1.23 1.07 – 1.41 0.00333 232 4169 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.19 0.98 – 1.46 0.079 106 2021 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.837 0.6 – 1.17 0.292 44 379 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.865 0.624 – 1.2 0.386 43 358 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.22 1.13 – 1.31 4.58e-08 945 8233 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.933 0.617 – 1.41 0.741 27 469 exclusion phecode
275.11 Hereditary hemochromatosis Hematopoietic 1.42 0.639 – 3.18 0.388 7 203 exclusion phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 0.844 0.477 – 1.49 0.559 15 153 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.48 1.3 – 1.69 6.22e-09 273 2426 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.18 1.09 – 1.27 5.54e-05 738 7005 exclusion phecode
275.51 Hypocalcemia Endocrine/metabolic 1.27 1.09 – 1.47 0.00189 218 1971 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.26 1.11 – 1.42 0.000253 320 2783 exclusion phecode
275.6 Hypercalcemia Endocrine/metabolic 1.22 1.08 – 1.39 0.00171 290 3120 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.23 1.17 – 1.29 5.29e-15 2041 8801 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.31 1.23 – 1.4 7.63e-18 1364 7723 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.26 1.03 – 1.54 0.0229 127 1035 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.35 1.23 – 1.47 4.05e-11 637 4587 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.36 1.25 – 1.49 1.28e-11 600 5079 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.39 1.26 – 1.55 3.79e-10 444 4590 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.23 1.11 – 1.36 9.51e-05 443 4136 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.24 1.11 – 1.39 0.00018 371 3556 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.34 1.1 – 1.63 0.00397 124 982 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.25 1.17 – 1.34 1.25e-11 1141 7954 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.47 1.27 – 1.69 1.67e-07 239 2587 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 0.942 0.627 – 1.41 0.773 24 289 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.12 1.03 – 1.21 0.00607 701 8379 exclusion phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.74 1.19 – 2.54 0.00443 28 771 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.04 0.882 – 1.23 0.624 161 1518 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.952 0.798 – 1.14 0.581 143 2051 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.981 0.803 – 1.2 0.852 109 1709 exclusion phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.79 1.14 – 2.8 0.011 17 1926 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.28 1.18 – 1.39 4.07e-09 678 10325 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.56 1.34 – 1.82 1.63e-08 177 10321 exclusion phecode
278.11 Morbid obesity Endocrine/metabolic 1.63 1.2 – 2.22 0.00167 40 10260 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 1.13 0.805 – 1.58 0.483 31 1298 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.17 1.04 – 1.32 0.00969 307 7284 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.1 1.02 – 1.19 0.0164 806 6578 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.17 1.04 – 1.32 0.0111 328 2565 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.16 0.924 – 1.46 0.199 93 720 exclusion phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 1.01 0.862 – 1.18 0.931 198 1809 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.02 0.956 – 1.09 0.544 1119 8305 exclusion phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 1.12 0.943 – 1.32 0.202 171 1473 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.16 1.08 – 1.24 2.21e-05 1078 7054 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.17 1.09 – 1.25 1.23e-05 1043 7020 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.19 1.07 – 1.32 0.00162 408 3775 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.31 1.06 – 1.61 0.0124 116 1161 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.36 1.02 – 1.8 0.0332 62 579 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.61 1.05 – 2.47 0.0297 28 267 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.26 0.887 – 1.78 0.198 43 434 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.2 0.915 – 1.58 0.186 63 652 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.21 0.937 – 1.57 0.142 69 693 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.16 0.839 – 1.6 0.374 46 437 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.55 1.11 – 2.18 0.0105 38 411 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.39 0.968 – 1.99 0.0744 33 345 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.1 0.677 – 1.8 0.692 15 152 exclusion phecode
284 Aplastic anemia Hematopoietic 1.3 1.11 – 1.52 0.00137 181 1365 exclusion phecode
284.1 Pancytopenia Hematopoietic 1.29 1.09 – 1.54 0.00365 157 1208 exclusion phecode
285 Other anemias Hematopoietic 1.16 1.1 – 1.21 6.9e-10 2829 7835 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.18 1.1 – 1.28 1.91e-05 806 5912 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.41 1.28 – 1.55 4.57e-12 523 4091 exclusion phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.5 1.29 – 1.73 8.08e-08 221 1743 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.31 1.11 – 1.54 0.00124 182 1437 exclusion phecode
286 Coagulation defects Hematopoietic 1.11 1.02 – 1.19 0.0116 767 7586 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.897 0.66 – 1.22 0.488 50 594 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.687 0.431 – 1.1 0.115 20 197 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.06 0.669 – 1.69 0.793 22 307 exclusion phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.08 0.988 – 1.19 0.0895 550 5391 exclusion phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 1.11 0.746 – 1.67 0.596 34 325 exclusion phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 1.05 0.78 – 1.41 0.749 50 500 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.966 0.663 – 1.41 0.856 24 279 exclusion phecode
286.6 Defibrination syndrome Hematopoietic 1.08 0.977 – 1.18 0.137 491 5592 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.07 0.978 – 1.17 0.146 588 6545 exclusion phecode
286.8 Hypercoagulable state Hematopoietic 1.09 0.916 – 1.29 0.337 158 1963 exclusion phecode
286.81 Primary hypercoagulable state Hematopoietic 1.07 0.894 – 1.27 0.475 150 1863 exclusion phecode
286.9 Abnormal coagulation profile Hematopoietic 1.28 1.11 – 1.48 0.00062 224 2405 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.11 1.02 – 1.2 0.0113 740 6201 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.763 0.563 – 1.03 0.0815 55 491 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.12 1.03 – 1.22 0.00768 671 5659 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.06 0.873 – 1.29 0.557 119 1303 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.14 0.945 – 1.38 0.169 135 1209 exclusion phecode
287.4 Qualitative platelet defects Hematopoietic 1.27 0.816 – 1.98 0.288 23 267 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.14 1.07 – 1.22 3.22e-05 1201 8361 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.14 1.04 – 1.26 0.00719 515 3506 exclusion phecode
288.11 Neutropenia Hematopoietic 1.23 1.09 – 1.38 0.00083 341 2383 exclusion phecode
288.2 Elevated white blood cell count Hematopoietic 1.14 1.06 – 1.22 0.000235 962 7794 exclusion phecode
288.3 Eosinophilia Hematopoietic 0.856 0.624 – 1.17 0.336 46 411 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.1 0.987 – 1.22 0.0858 440 3991 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.02 0.881 – 1.17 0.816 232 2168 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.08 1 – 1.15 0.0418 946 7908 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1.21 0.959 – 1.54 0.107 79 834 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.44 1.01 – 2.05 0.0419 40 463 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.46 1.16 – 1.83 0.00111 99 843 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.07 0.951 – 1.21 0.253 326 2192 exclusion phecode
290.1 Dementias Mental Disorders 0.91 0.746 – 1.11 0.356 116 945 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.975 0.658 – 1.45 0.901 32 269 exclusion phecode
290.12 Dementia with cerebral degenerations Mental Disorders 0.598 0.351 – 1.02 0.0583 15 151 exclusion phecode
290.13 Senile dementia Mental Disorders 0.879 0.687 – 1.12 0.304 75 604 exclusion phecode
290.16 Vascular dementia Mental Disorders 1.11 0.67 – 1.83 0.694 20 144 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.12 0.958 – 1.31 0.155 200 1357 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.03 0.891 – 1.2 0.674 208 1877 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.14 1.04 – 1.25 0.00455 540 5706 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.847 0.604 – 1.19 0.334 36 500 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.07 0.895 – 1.29 0.442 135 1160 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.18 1.06 – 1.31 0.0028 404 4403 exclusion phecode
292 Neurological disorders Mental Disorders 1.11 1.05 – 1.18 0.000493 1340 8914 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.13 1.03 – 1.24 0.0131 514 4104 exclusion phecode
292.11 Aphasia Mental Disorders 1.05 0.889 – 1.25 0.546 158 1414 exclusion phecode
292.12 Symbolic dysfunction Mental Disorders 0.888 0.648 – 1.22 0.459 45 448 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 1.02 0.813 – 1.28 0.862 83 779 exclusion phecode
292.3 Memory loss Mental Disorders 0.929 0.835 – 1.03 0.177 394 3874 exclusion phecode
292.4 Altered mental status Mental Disorders 1.24 1.13 – 1.36 6.19e-06 544 4644 exclusion phecode
292.5 Transient alteration of awareness Mental Disorders 1.02 0.826 – 1.26 0.853 105 944 exclusion phecode
292.6 Hallucinations Mental Disorders 1.36 0.998 – 1.86 0.0514 50 472 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.15 0.932 – 1.41 0.198 109 942 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.08 1.01 – 1.16 0.0237 1033 8730 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.18 1.02 – 1.37 0.0284 211 1890 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.14 0.786 – 1.66 0.485 30 327 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.49 0.944 – 2.34 0.087 24 252 exclusion phecode
295.3 Psychosis Mental Disorders 1.22 1.03 – 1.43 0.0211 175 1527 exclusion phecode
296 Mood disorders Mental Disorders 1.1 1.05 – 1.15 9.97e-05 3358 5135 exclusion phecode
296.1 Bipolar Mental Disorders 1.19 1.05 – 1.36 0.00784 288 3055 exclusion phecode
296.2 Depression Mental Disorders 1.09 1.04 – 1.15 0.000161 3217 5134 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.1 1.05 – 1.15 0.000135 2978 5134 exclusion phecode
297 Suicidal ideation or attempt Mental Disorders 1.33 1.17 – 1.52 2.73e-05 273 2462 exclusion phecode
297.1 Suicidal ideation Mental Disorders 1.29 1.11 – 1.5 0.000822 211 2001 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.36 1.09 – 1.7 0.00697 99 768 exclusion phecode
300 Anxiety disorders Mental Disorders 1.11 1.06 – 1.16 2.72e-06 3742 5135 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.12 1.07 – 1.18 5.67e-07 3556 5135 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 1.11 1.04 – 1.19 0.00136 1339 4978 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.05 0.925 – 1.19 0.456 330 3115 exclusion phecode
300.13 Phobia Mental Disorders 1.11 0.958 – 1.28 0.169 243 2450 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.749 0.578 – 0.971 0.0289 75 881 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.11 1.01 – 1.22 0.0263 590 4164 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.11 0.888 – 1.38 0.363 103 1260 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.17 0.998 – 1.37 0.0536 192 2136 exclusion phecode
301 Personality disorders Mental Disorders 1.24 1.01 – 1.53 0.0363 110 1340 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.27 0.97 – 1.66 0.0822 64 700 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 0.932 0.846 – 1.03 0.15 544 2894 exclusion phecode
302.1 Decreased libido Mental Disorders 0.757 0.606 – 0.947 0.0148 97 1003 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.926 0.87 – 0.984 0.0139 1620 4752 exclusion phecode
303.1 Dissociative disorder Mental Disorders 0.972 0.675 – 1.4 0.881 32 423 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.924 0.867 – 0.983 0.0129 1550 4697 exclusion phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.807 0.662 – 0.984 0.034 120 1144 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.984 0.868 – 1.12 0.805 312 3000 exclusion phecode
304 Adjustment reaction Mental Disorders 1.09 1.01 – 1.18 0.0188 930 4959 exclusion phecode
305.2 Eating disorder Mental Disorders 1.26 1.06 – 1.51 0.0106 145 2340 exclusion phecode
306 Other mental disorder Mental Disorders 1.05 0.944 – 1.16 0.398 464 3668 exclusion phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.05 0.876 – 1.26 0.604 156 1234 exclusion phecode
306.9 Tension headache Mental Disorders 0.966 0.825 – 1.13 0.664 189 2011 exclusion phecode
312 Conduct disorders Mental Disorders 1.21 0.934 – 1.57 0.15 74 661 exclusion phecode
312.3 Impulse control disorder Mental Disorders 0.995 0.635 – 1.56 0.982 23 218 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 1.06 0.962 – 1.17 0.236 467 4203 exclusion phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1.08 0.97 – 1.2 0.165 423 3835 exclusion phecode
313.2 Tics and stuttering Mental Disorders 0.91 0.574 – 1.44 0.689 23 217 exclusion phecode
313.3 Autism Mental Disorders 0.927 0.536 – 1.6 0.787 12 202 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.01 0.857 – 1.2 0.878 167 1581 exclusion phecode
315.1 Learning disorder Mental Disorders 0.974 0.651 – 1.46 0.897 25 273 exclusion phecode
315.2 Speech and language disorder Mental Disorders 1.01 0.772 – 1.32 0.934 62 604 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.32 1.23 – 1.42 1.21e-14 963 7539 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.993 0.834 – 1.18 0.936 153 1360 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.23 1.13 – 1.34 1.79e-06 671 4789 exclusion phecode
317.1 Alcoholism Mental Disorders 1.23 1.13 – 1.35 8.2e-06 561 3801 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.08 0.847 – 1.37 0.542 81 651 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.31 1.24 – 1.38 2.78e-24 2004 8160 exclusion phecode
320 Meningitis Neurological 1.01 0.817 – 1.26 0.893 101 872 exclusion phecode
323 Encephalitis Neurological 1.35 0.979 – 1.85 0.0671 45 392 exclusion phecode
323.8 Encephalitis, non-infectious Neurological 1.33 0.922 – 1.91 0.127 39 330 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.02 0.767 – 1.35 0.898 52 626 exclusion phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 1.32 0.647 – 2.69 0.444 10 118 exclusion phecode
327 Sleep disorders Neurological 1.03 0.982 – 1.09 0.207 2171 8803 exclusion phecode
327.1 Hypersomnia Neurological 0.992 0.874 – 1.13 0.908 266 5126 exclusion phecode
327.3 Sleep apnea Neurological 0.968 0.901 – 1.04 0.383 898 8640 exclusion phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1.1 0.871 – 1.38 0.436 81 1103 exclusion phecode
327.32 Obstructive sleep apnea Neurological 0.96 0.882 – 1.04 0.339 639 8241 exclusion phecode
327.4 Insomnia Neurological 1.05 0.985 – 1.12 0.135 1270 8485 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.01 0.894 – 1.15 0.832 286 3274 exclusion phecode
327.5 Parasomnia Neurological 1.06 0.842 – 1.34 0.614 74 1455 exclusion phecode
327.6 Circadian rhythm sleep disorder Neurological 0.84 0.622 – 1.13 0.255 54 740 exclusion phecode
327.7 Sleep related movement disorders Neurological 1.04 0.919 – 1.17 0.551 304 4527 exclusion phecode
327.71 Restless legs syndrome Neurological 1.05 0.919 – 1.19 0.488 263 4037 exclusion phecode
327.72 Sleep related leg cramps Neurological 0.969 0.606 – 1.55 0.894 18 181 exclusion phecode
331 Other cerebral degenerations Neurological 1.18 1 – 1.39 0.0503 175 1452 exclusion phecode
331.1 Hydrocephalus Neurological 1.14 0.889 – 1.47 0.3 69 663 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.2 0.967 – 1.49 0.0984 105 817 exclusion phecode
332 Parkinson's disease Neurological 1.07 0.869 – 1.33 0.507 99 706 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.03 0.947 – 1.13 0.454 607 5909 exclusion phecode
333.1 Essential tremor Neurological 1.03 0.87 – 1.21 0.754 163 1443 exclusion phecode
333.2 Myoclonus Neurological 1.09 0.78 – 1.53 0.606 39 365 exclusion phecode
333.4 Torsion dystonia Neurological 0.952 0.776 – 1.17 0.637 113 785 exclusion phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 0.85 0.552 – 1.31 0.462 29 168 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.15 0.993 – 1.33 0.0615 223 2251 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.44 0.885 – 2.36 0.141 21 164 exclusion phecode
334.2 Anterior horn cell disease Neurological 1.58 1.01 – 2.45 0.044 25 213 exclusion phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 1.61 0.906 – 2.85 0.104 17 119 exclusion phecode
335 Multiple sclerosis Neurological 1.01 0.815 – 1.24 0.956 101 931 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.08 0.924 – 1.25 0.344 203 1628 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.41 1.1 – 1.82 0.0072 73 560 exclusion phecode
338 Pain Neurological 1.11 1.06 – 1.15 5.26e-07 4506 6507 exclusion phecode
338.1 Acute pain Neurological 1.12 1.08 – 1.17 1.11e-07 3556 6458 exclusion phecode
338.2 Chronic pain Neurological 1.14 1.08 – 1.2 1.26e-06 2162 6474 exclusion phecode
339 Other headache syndromes Neurological 1.06 1.01 – 1.11 0.0274 2155 8099 exclusion phecode
340 Migraine Neurological 1.05 0.99 – 1.11 0.107 1690 7395 exclusion phecode
340.1 Migrain with aura Neurological 1.12 1.04 – 1.2 0.00369 915 6012 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.965 0.667 – 1.4 0.852 34 302 exclusion phecode
342 Hemiplegia Neurological 1.14 0.933 – 1.39 0.203 110 966 exclusion phecode
343 Infantile cerebral palsy Neurological 1.32 0.897 – 1.94 0.158 25 246 exclusion phecode
344 Other paralytic syndromes Neurological 1.26 1.06 – 1.49 0.00751 171 1436 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.1 1.01 – 1.2 0.0229 654 5981 exclusion phecode
345.1 Epilepsy Neurological 1.05 0.897 – 1.23 0.539 194 1787 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 0.901 0.679 – 1.2 0.469 57 582 exclusion phecode
345.12 Partial epilepsy Neurological 0.997 0.826 – 1.2 0.974 138 1235 exclusion phecode
345.3 Convulsions Neurological 1.11 1.02 – 1.22 0.014 620 5634 exclusion phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.979 0.706 – 1.36 0.896 40 423 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.06 0.943 – 1.19 0.334 338 3127 exclusion phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.914 0.612 – 1.37 0.663 28 262 exclusion phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 1.3 0.793 – 2.14 0.297 19 257 exclusion phecode
347 Cataplexy and narcolepsy Neurological 1.16 0.745 – 1.82 0.504 20 250 exclusion phecode
348 Other conditions of brain Neurological 1.14 1.03 – 1.26 0.0146 425 4047 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.09 0.942 – 1.26 0.252 215 2071 exclusion phecode
348.4 Cerebral cysts Neurological 0.816 0.612 – 1.09 0.168 53 566 exclusion phecode
348.7 Coma Neurological 1.4 1.05 – 1.86 0.0218 57 529 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.43 1.22 – 1.67 8.34e-06 195 1750 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.04 0.95 – 1.14 0.38 532 5180 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.18 1.02 – 1.36 0.0236 234 2163 exclusion phecode
350 Abnormal movement Neurological 1.09 1.03 – 1.15 0.00454 1494 9072 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.13 1.05 – 1.23 0.00181 750 6804 exclusion phecode
350.2 Abnormality of gait Neurological 1.1 1.02 – 1.18 0.0191 815 6558 exclusion phecode
350.3 Lack of coordination Neurological 1.04 0.915 – 1.18 0.569 293 2332 exclusion phecode
350.5 Abnormal reflex Neurological 1.12 0.821 – 1.53 0.471 43 453 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.989 0.809 – 1.21 0.917 118 1103 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.07 1 – 1.13 0.037 1352 8345 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.1 0.987 – 1.23 0.0852 379 4003 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.17 0.968 – 1.42 0.103 125 1317 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.05 0.891 – 1.24 0.553 161 1792 exclusion phecode
353 Nerve root and plexus disorders Neurological 1.07 0.997 – 1.16 0.0594 843 7874 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.982 0.8 – 1.21 0.863 110 956 exclusion phecode
353.2 Nerve root lesions Neurological 1.15 0.749 – 1.78 0.514 24 257 exclusion phecode
355 Complex regional/central pain syndrome Neurological 1.08 0.898 – 1.3 0.41 131 1290 exclusion phecode
355.1 Chronic pain syndrome Neurological 1.22 1.05 – 1.43 0.0119 181 1965 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.13 1.02 – 1.26 0.0228 395 4283 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.09 0.998 – 1.19 0.0562 623 6312 exclusion phecode
358 Myoneural disorders Neurological 1.1 0.959 – 1.26 0.173 248 2514 exclusion phecode
358.1 Myasthenia gravis Neurological 0.824 0.55 – 1.23 0.348 26 245 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.95 0.841 – 1.07 0.412 309 2559 exclusion phecode
359.1 Muscular dystrophies Neurological 0.954 0.572 – 1.59 0.858 22 153 exclusion phecode
359.2 Myopathy Neurological 0.948 0.837 – 1.07 0.403 294 2454 exclusion phecode
360 Disorders of the globe Sense Organs 1.03 0.699 – 1.52 0.873 30 266 exclusion phecode
360.2 Progressive myopia Sense Organs 0.786 0.472 – 1.31 0.356 19 128 exclusion phecode
361 Retinal detachments and defects Sense Organs 1.04 0.881 – 1.23 0.625 156 1427 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.926 0.706 – 1.21 0.58 65 551 exclusion phecode
362 Other retinal disorders Sense Organs 1.04 0.955 – 1.13 0.383 747 4729 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.964 0.867 – 1.07 0.5 450 3086 exclusion phecode
362.21 Macular degeneration, dry Sense Organs 0.903 0.711 – 1.15 0.407 89 722 exclusion phecode
362.22 Macular degeneration, wet Sense Organs 0.905 0.606 – 1.35 0.626 34 253 exclusion phecode
362.23 Cystoid macular degeneration of retina Sense Organs 0.971 0.777 – 1.21 0.798 88 800 exclusion phecode
362.26 Macular puckering of retina Sense Organs 0.901 0.763 – 1.06 0.214 173 1667 exclusion phecode
362.27 Drusen (degenerative) of retina Sense Organs 1.04 0.845 – 1.28 0.707 114 930 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.964 0.863 – 1.08 0.519 403 2769 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.19 1.02 – 1.4 0.0308 174 1727 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1.41 1.14 – 1.75 0.00189 87 771 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.982 0.815 – 1.18 0.852 134 1199 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.999 0.805 – 1.24 0.995 97 793 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.15 0.85 – 1.56 0.363 50 491 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.12 0.843 – 1.48 0.438 62 476 exclusion phecode
362.9 Retinal edema Sense Organs 1.13 0.857 – 1.48 0.393 59 565 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.963 0.783 – 1.19 0.724 114 962 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.953 0.741 – 1.23 0.708 73 644 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.986 0.866 – 1.12 0.831 283 2369 exclusion phecode
364.1 Corneal opacity Sense Organs 0.957 0.771 – 1.19 0.692 104 821 exclusion phecode
364.2 Corneal edema Sense Organs 1.15 0.761 – 1.75 0.498 22 244 exclusion phecode
364.4 Corneal degenerations Sense Organs 1.02 0.842 – 1.25 0.809 118 907 exclusion phecode
364.41 Keratoconus Sense Organs 0.565 0.337 – 0.948 0.0308 21 155 exclusion phecode
364.5 Corneal dystrophy Sense Organs 1.06 0.859 – 1.31 0.583 106 998 exclusion phecode
364.51 Fuchs' dystrophy Sense Organs 1.09 0.818 – 1.46 0.553 60 530 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.737 0.442 – 1.23 0.243 17 188 exclusion phecode
365 Glaucoma Sense Organs 0.983 0.896 – 1.08 0.721 573 4343 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 1.06 0.896 – 1.27 0.476 166 1308 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.961 0.758 – 1.22 0.743 93 729 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.919 0.688 – 1.23 0.57 67 484 exclusion phecode
366 Cataract Sense Organs 0.998 0.94 – 1.06 0.952 1738 5909 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.887 0.665 – 1.18 0.411 56 430 exclusion phecode
366.2 Senile cataract Sense Organs 0.97 0.902 – 1.04 0.41 1076 5140 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.946 0.899 – 0.996 0.0351 2073 8929 exclusion phecode
367.1 Myopia Sense Organs 0.904 0.848 – 0.963 0.00193 1236 8271 exclusion phecode
367.2 Astigmatism Sense Organs 0.916 0.853 – 0.984 0.0163 963 7507 exclusion phecode
367.8 Hypermetropia Sense Organs 0.936 0.844 – 1.04 0.206 439 4193 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.14 1 – 1.3 0.0435 276 2785 exclusion phecode
368 Visual disturbances Sense Organs 1.02 0.962 – 1.09 0.479 1304 9189 exclusion phecode
368.1 Amblyopia Sense Organs 1.15 0.955 – 1.37 0.143 142 1495 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.03 0.904 – 1.18 0.618 257 2306 exclusion phecode
368.3 Anisometropia Sense Organs 0.864 0.65 – 1.15 0.315 57 494 exclusion phecode
368.4 Visual field defects Sense Organs 0.952 0.821 – 1.1 0.516 202 2398 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.963 0.84 – 1.1 0.587 246 2456 exclusion phecode
368.91 Psychophysical visual disturbances Sense Organs 1.02 0.668 – 1.56 0.927 30 248 exclusion phecode
369 Infection of the eye Sense Organs 0.917 0.847 – 0.992 0.0301 768 6955 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.872 0.716 – 1.06 0.174 126 1209 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.913 0.839 – 0.994 0.0359 653 6187 exclusion phecode
370 Keratitis Sense Organs 0.881 0.784 – 0.989 0.0324 363 3031 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.875 0.669 – 1.14 0.328 73 497 exclusion phecode
370.2 Superficial keratitis Sense Organs 0.887 0.734 – 1.07 0.213 135 1226 exclusion phecode
370.3 Keratoconjunctivitis Sense Organs 0.976 0.824 – 1.16 0.775 170 1469 exclusion phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.893 0.658 – 1.21 0.466 51 429 exclusion phecode
371 Inflammation of the eye Sense Organs 0.956 0.893 – 1.02 0.202 1061 7190 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.04 0.856 – 1.26 0.701 126 1173 exclusion phecode
371.2 Conjunctivitis, noninfectious Sense Organs 1.04 0.893 – 1.21 0.629 208 2101 exclusion phecode
371.21 Allergic conjunctivitis Sense Organs 1.04 0.885 – 1.23 0.615 171 1761 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.931 0.862 – 1.01 0.0699 827 5881 exclusion phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 0.993 0.72 – 1.37 0.966 45 323 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.01 0.885 – 1.15 0.9 270 2280 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.917 0.842 – 0.999 0.0461 666 5197 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.817 0.661 – 1.01 0.0616 104 867 exclusion phecode
374.2 Lagophthalmos Sense Organs 1.16 0.895 – 1.5 0.262 71 518 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.987 0.859 – 1.13 0.852 248 2311 exclusion phecode
374.6 Dermatochalasis Sense Organs 0.937 0.803 – 1.09 0.413 193 2010 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.971 0.9 – 1.05 0.441 897 5809 exclusion phecode
375.1 Dry eyes Sense Organs 0.974 0.905 – 1.05 0.474 970 5921 exclusion phecode
375.2 Epiphora Sense Organs 0.941 0.762 – 1.16 0.571 109 943 exclusion phecode
376 Disorders of the orbit Sense Organs 1.04 0.824 – 1.31 0.741 85 816 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.1 0.942 – 1.29 0.226 187 2041 exclusion phecode
377.1 Optic atrophy Sense Organs 0.93 0.707 – 1.22 0.602 61 600 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.19 0.975 – 1.45 0.0866 118 1325 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.16 1.02 – 1.31 0.0218 308 2832 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.15 0.983 – 1.33 0.0822 195 1886 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.11 0.805 – 1.52 0.532 44 362 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.11 0.868 – 1.41 0.416 83 745 exclusion phecode
379 Other disorders of eye Sense Organs 0.987 0.922 – 1.06 0.716 1109 6488 exclusion phecode
379.1 Scleritis and episcleritis Sense Organs 0.865 0.62 – 1.21 0.394 45 414 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.967 0.891 – 1.05 0.412 783 4805 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.884 0.614 – 1.27 0.509 38 278 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.13 0.862 – 1.48 0.379 62 614 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.1 0.852 – 1.43 0.458 73 591 exclusion phecode
379.51 Pigmentary iris degeneration Sense Organs 0.773 0.44 – 1.36 0.37 18 138 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.933 0.814 – 1.07 0.314 268 2541 exclusion phecode
380 Disorders of external ear Sense Organs 0.942 0.857 – 1.04 0.214 533 4433 exclusion phecode
380.1 Otitis externa Sense Organs 0.857 0.756 – 0.97 0.015 292 3392 exclusion phecode
380.4 Impacted cerumen Sense Organs 0.909 0.833 – 0.992 0.0327 622 5170 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1 0.937 – 1.08 0.903 984 8885 exclusion phecode
381.1 Otitis media Sense Organs 1.03 0.947 – 1.11 0.523 692 7540 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.04 0.949 – 1.13 0.425 570 6551 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.93 0.842 – 1.03 0.158 456 4389 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 1.08 0.76 – 1.54 0.663 30 367 exclusion phecode
381.9 Otorrhea Sense Organs 1.2 0.944 – 1.53 0.137 82 892 exclusion phecode
382 Otalgia Sense Organs 0.999 0.905 – 1.1 0.992 473 4795 exclusion phecode
383 Otosclerosis Sense Organs 1.08 0.764 – 1.53 0.654 33 289 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 0.941 0.775 – 1.14 0.539 126 1334 exclusion phecode
384.1 Myringitis Sense Organs 0.781 0.433 – 1.41 0.41 13 126 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 0.904 0.728 – 1.12 0.364 100 1050 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.896 0.736 – 1.09 0.276 115 1063 exclusion phecode
385.3 Cholesteatoma Sense Organs 0.903 0.711 – 1.15 0.402 77 704 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.878 0.627 – 1.23 0.448 42 313 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.978 0.876 – 1.09 0.692 389 4144 exclusion phecode
386.1 Meniere's disease Sense Organs 1.01 0.777 – 1.3 0.961 69 699 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.972 0.86 – 1.1 0.65 313 3465 exclusion phecode
386.21 Central origin vertigo Sense Organs 0.944 0.82 – 1.09 0.421 239 2681 exclusion phecode
386.3 Labyrinthitis Sense Organs 0.938 0.83 – 1.06 0.311 305 3323 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.03 0.968 – 1.09 0.388 1533 8939 exclusion phecode
388 Other disorders of ear Sense Organs 1.1 0.956 – 1.27 0.184 235 2220 exclusion phecode
389 Hearing loss Sense Organs 1.01 0.957 – 1.07 0.698 1750 9108 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.98 0.909 – 1.06 0.597 866 6253 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.03 0.899 – 1.19 0.639 231 2287 exclusion phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.945 0.669 – 1.33 0.745 45 353 exclusion phecode
389.4 Tinnitus Sense Organs 1.05 0.953 – 1.15 0.342 536 4740 exclusion phecode
389.5 Disorders of acoustic nerve Sense Organs 1.16 0.811 – 1.65 0.422 35 268 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.12 0.987 – 1.26 0.0796 313 2691 exclusion phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 1.03 0.797 – 1.34 0.807 71 628 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.11 0.894 – 1.37 0.353 103 958 exclusion phecode
394.3 Aortic valve disease Circulatory System 0.981 0.666 – 1.45 0.923 25 304 exclusion phecode
394.4 Acute rheumatic heart disease Circulatory System 0.975 0.561 – 1.7 0.93 11 124 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.06 0.88 – 1.27 0.551 146 1151 exclusion phecode
395 Heart valve disorders Circulatory System 1.09 1.01 – 1.17 0.0278 885 6001 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.05 0.953 – 1.15 0.34 538 4304 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.17 1.04 – 1.31 0.00779 378 3214 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 0.964 0.786 – 1.18 0.728 121 1016 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.35 0.915 – 2 0.13 29 245 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.14 0.981 – 1.33 0.0859 205 2036 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.06 0.994 – 1.14 0.0725 1089 7743 exclusion phecode
401 Hypertension Circulatory System 1.15 1.1 – 1.21 1.8e-08 3346 7626 exclusion phecode
401.1 Essential hypertension Circulatory System 1.15 1.09 – 1.21 2.67e-08 3302 7627 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.36 1.24 – 1.5 2.59e-10 559 4287 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.14 0.936 – 1.38 0.196 115 1846 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.41 1.27 – 1.57 2.55e-10 433 3799 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.29 1.17 – 1.42 5.37e-07 489 4747 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.2 1.12 – 1.27 3.13e-08 1399 6875 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.01 0.832 – 1.23 0.908 114 1634 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.22 1.11 – 1.34 2.72e-05 581 4475 exclusion phecode
411.3 Angina pectoris Circulatory System 1.19 1.06 – 1.34 0.00286 351 3742 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.19 1.11 – 1.28 6.23e-07 1170 6026 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.14 0.734 – 1.75 0.569 22 310 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.21 1.12 – 1.3 6.46e-07 935 5489 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.2 0.942 – 1.52 0.142 78 862 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.19 1.09 – 1.31 0.000239 537 4888 exclusion phecode
414.2 ASCVD Circulatory System 1.13 0.916 – 1.39 0.258 105 1390 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.16 1.06 – 1.27 0.000866 568 6409 exclusion phecode
415.1 Acute pulmonary heart disease Circulatory System 1.16 1.03 – 1.31 0.0167 307 4016 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.16 1.03 – 1.31 0.0154 306 3996 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.19 1.06 – 1.34 0.00387 325 3624 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.18 0.986 – 1.42 0.0713 141 1459 exclusion phecode
416 Cardiomegaly Circulatory System 1.22 1.06 – 1.41 0.00676 223 2598 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.04 0.998 – 1.09 0.0634 2663 8303 exclusion phecode
418.1 Precordial pain Circulatory System 1.02 0.897 – 1.17 0.741 257 2916 exclusion phecode
420 Carditis Circulatory System 1.03 0.912 – 1.16 0.656 325 3199 exclusion phecode
420.1 Myocarditis Circulatory System 1.51 0.916 – 2.48 0.107 16 212 exclusion phecode
420.2 Pericarditis Circulatory System 1.01 0.86 – 1.19 0.888 176 1693 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.07 0.784 – 1.47 0.665 43 368 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.01 0.636 – 1.59 0.98 21 235 exclusion phecode
420.3 Endocarditis Circulatory System 0.994 0.837 – 1.18 0.946 162 1555 exclusion phecode
425 Cardiomyopathy Circulatory System 1.15 1.03 – 1.29 0.0148 365 3873 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.14 1.01 – 1.27 0.0284 347 3682 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.02 0.686 – 1.52 0.914 30 393 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.38 0.921 – 2.06 0.119 26 421 exclusion phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.14 0.894 – 1.46 0.284 72 673 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.83 1.11 – 3.03 0.0183 24 212 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.09 1.03 – 1.15 0.00155 2393 6433 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.08 0.944 – 1.23 0.271 282 2269 exclusion phecode
426.21 First degree AV block Circulatory System 1.03 0.872 – 1.21 0.744 184 1698 exclusion phecode
426.22 Mobitz II AV block Circulatory System 1.41 0.729 – 2.73 0.307 11 121 exclusion phecode
426.23 Second degree AV block Circulatory System 1.12 0.8 – 1.56 0.512 41 380 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 0.97 0.76 – 1.24 0.807 85 744 exclusion phecode
426.25 Other heart block Circulatory System 1.24 0.876 – 1.75 0.228 38 337 exclusion phecode
426.3 Bundle branch block Circulatory System 1.04 0.924 – 1.16 0.54 378 2927 exclusion phecode
426.31 Right bundle branch block Circulatory System 0.992 0.86 – 1.14 0.914 235 2178 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.07 0.9 – 1.28 0.438 152 1610 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.915 0.607 – 1.38 0.672 24 216 exclusion phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.1 1.04 – 1.17 0.000504 2072 6305 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.29 1.07 – 1.57 0.00922 137 1431 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.11 0.976 – 1.26 0.114 305 2302 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.15 0.976 – 1.35 0.0957 189 1569 exclusion phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.16 0.975 – 1.38 0.0951 150 1374 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.04 0.993 – 1.08 0.103 3759 6569 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.06 0.959 – 1.16 0.27 517 4083 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.01 0.9 – 1.13 0.879 360 3264 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.14 0.983 – 1.33 0.0829 212 1952 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.03 0.948 – 1.12 0.497 880 4073 exclusion phecode
427.21 Atrial fibrillation Circulatory System 1.01 0.933 – 1.1 0.756 850 3984 exclusion phecode
427.22 Atrial flutter Circulatory System 0.925 0.809 – 1.06 0.257 270 2103 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.07 1.01 – 1.13 0.0204 1873 6497 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.968 0.773 – 1.21 0.78 89 1045 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.01 0.704 – 1.46 0.947 31 405 exclusion phecode
427.42 Cardiac arrest Circulatory System 0.965 0.753 – 1.24 0.775 76 797 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.01 0.953 – 1.08 0.661 1413 6465 exclusion phecode
427.6 Premature beats Circulatory System 0.913 0.822 – 1.01 0.0917 451 3494 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 0.963 0.802 – 1.16 0.683 144 1322 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.13 1.06 – 1.21 0.000185 1198 6476 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.97 0.821 – 1.15 0.724 174 1536 exclusion phecode
427.9 Palpitations Circulatory System 0.917 0.856 – 0.984 0.0153 1079 6085 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.22 1.12 – 1.32 6.72e-06 692 5011 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.19 1.09 – 1.3 0.000164 592 4695 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.26 1.15 – 1.38 1.23e-06 568 4489 exclusion phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.26 1.11 – 1.43 0.000237 312 2812 exclusion phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.31 1.12 – 1.52 0.000479 207 2667 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.08 1.03 – 1.13 0.00231 2642 8036 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.16 1.01 – 1.33 0.0303 243 2297 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.16 1.09 – 1.24 1.23e-05 1140 6729 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.06 1.01 – 1.12 0.0178 2144 7990 exclusion phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.2 0.989 – 1.45 0.0648 123 1402 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.09 0.927 – 1.28 0.3 183 1622 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.35 1.02 – 1.79 0.0379 60 542 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.13 0.891 – 1.42 0.319 87 759 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.14 0.885 – 1.47 0.31 73 525 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.11 1.04 – 1.19 0.0019 1116 6795 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.13 1.01 – 1.25 0.0288 418 3096 exclusion phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.04 0.786 – 1.38 0.783 60 505 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 0.791 0.466 – 1.34 0.384 16 154 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.17 1.06 – 1.29 0.00236 482 4311 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.17 1.06 – 1.29 0.00255 467 4173 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.06 0.97 – 1.17 0.189 558 4590 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.06 0.964 – 1.18 0.215 483 4143 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.16 0.95 – 1.41 0.149 123 1079 exclusion phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 0.993 0.78 – 1.26 0.953 76 904 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.1 0.921 – 1.32 0.285 139 1421 exclusion phecode
440 Atherosclerosis Circulatory System 1.14 1.03 – 1.25 0.0121 483 3834 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.987 0.734 – 1.33 0.931 53 473 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.06 0.931 – 1.2 0.399 289 2602 exclusion phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.29 0.972 – 1.7 0.0781 57 444 exclusion phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 0.98 0.843 – 1.14 0.793 202 1833 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.14 0.953 – 1.35 0.156 146 1519 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.2 0.996 – 1.44 0.0552 141 1086 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.997 0.766 – 1.3 0.98 64 493 exclusion phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.14 0.833 – 1.55 0.42 49 341 exclusion phecode
442 Other aneurysm Circulatory System 1.14 1.04 – 1.25 0.00662 538 4204 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.1 0.98 – 1.23 0.106 359 3044 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.04 0.901 – 1.2 0.579 231 1842 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 0.926 0.618 – 1.39 0.709 26 331 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.2 0.812 – 1.78 0.36 26 317 exclusion phecode
442.4 Arterial dissection Circulatory System 0.911 0.662 – 1.25 0.567 41 360 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.35 1.07 – 1.7 0.0108 97 829 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.08 0.994 – 1.17 0.0708 751 5181 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 0.968 0.85 – 1.1 0.631 299 1780 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.54 0.993 – 2.39 0.0537 25 321 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.08 0.993 – 1.18 0.0714 633 4524 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.17 1.06 – 1.29 0.00205 470 3653 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.14 0.977 – 1.32 0.0982 205 1687 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.06 0.836 – 1.33 0.645 85 563 exclusion phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 0.991 0.683 – 1.44 0.96 33 254 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.04 0.844 – 1.27 0.739 112 996 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.86 0.575 – 1.29 0.462 29 233 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.13 0.68 – 1.89 0.629 17 155 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.02 0.794 – 1.32 0.86 74 611 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.13 1.03 – 1.24 0.00854 541 4593 exclusion phecode
447.1 Stricture of artery Circulatory System 1.1 0.912 – 1.34 0.309 127 1103 exclusion phecode
447.7 Aortic ectasia Circulatory System 1.11 0.913 – 1.36 0.287 110 1448 exclusion phecode
448 Disease of capillaries Circulatory System 0.82 0.728 – 0.923 0.00102 338 2641 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.09 0.984 – 1.21 0.0999 431 4714 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.934 0.786 – 1.11 0.433 154 1664 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.932 0.658 – 1.32 0.693 39 565 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1.09 1.02 – 1.17 0.0158 915 7002 exclusion phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1.05 0.747 – 1.48 0.78 32 571 exclusion phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1.08 0.993 – 1.18 0.0709 596 6075 exclusion phecode
452.8 Postphlebitic syndrome Circulatory System 0.731 0.451 – 1.19 0.204 21 348 exclusion phecode
453 Chronic venous hypertension Circulatory System 0.969 0.703 – 1.33 0.845 47 476 exclusion phecode
454 Varicose veins Circulatory System 1.03 0.946 – 1.13 0.474 608 5675 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1.04 0.941 – 1.14 0.467 514 4894 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.994 0.88 – 1.12 0.916 316 3463 exclusion phecode
455 Hemorrhoids Circulatory System 0.947 0.889 – 1.01 0.0928 1282 6964 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.96 0.877 – 1.05 0.373 567 5684 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.07 0.959 – 1.2 0.219 364 3134 exclusion phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1 0.753 – 1.33 0.998 55 598 exclusion phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.07 0.95 – 1.2 0.271 336 2996 exclusion phecode
458 Hypotension Circulatory System 1.22 1.14 – 1.3 2.53e-09 1176 7346 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.2 1.06 – 1.35 0.00394 332 2790 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.19 1.03 – 1.37 0.0157 240 2177 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.23 1.15 – 1.32 3.24e-09 1063 7007 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.12 1.05 – 1.19 0.00019 1488 8249 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.1 0.941 – 1.29 0.227 198 1796 exclusion phecode
459.7 Blood vessel replaced Circulatory System 1.16 1.02 – 1.32 0.0272 270 2697 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.09 1.02 – 1.17 0.00726 1216 7763 exclusion phecode
464 Acute sinusitis Respiratory 1 0.937 – 1.07 0.929 1058 7669 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.974 0.928 – 1.02 0.288 2314 8379 exclusion phecode
465.2 Acute pharyngitis Respiratory 0.965 0.908 – 1.03 0.249 1387 7845 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.927 0.747 – 1.15 0.491 99 1091 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.973 0.878 – 1.08 0.595 447 4242 exclusion phecode
471 Nasal polyps Respiratory 0.88 0.729 – 1.06 0.185 128 1347 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.883 0.792 – 0.984 0.0244 386 4089 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.1 1.02 – 1.19 0.0146 765 5620 exclusion phecode
473.1 Chronic laryngitis Respiratory 0.943 0.516 – 1.72 0.85 15 141 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.05 0.881 – 1.26 0.572 152 1442 exclusion phecode
473.4 Voice disturbance Respiratory 1.12 1.03 – 1.22 0.0116 621 4837 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1.11 0.976 – 1.26 0.112 289 2465 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.05 0.867 – 1.26 0.64 129 1165 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.11 0.959 – 1.28 0.166 220 2021 exclusion phecode
475 Chronic sinusitis Respiratory 1.05 0.976 – 1.12 0.195 987 6534 exclusion phecode
475.9 Postnasal drip Respiratory 0.939 0.803 – 1.1 0.43 196 1995 exclusion phecode
476 Allergic rhinitis Respiratory 0.984 0.94 – 1.03 0.505 2895 6585 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.24 1.09 – 1.41 0.00132 266 2574 exclusion phecode
478 Throat pain Respiratory 1.16 0.958 – 1.42 0.127 120 1024 exclusion phecode
479 Other upper respiratory disease Respiratory 1.08 1.01 – 1.15 0.02 1311 6567 exclusion phecode
480 Pneumonia Respiratory 1.13 1.06 – 1.2 0.000136 1287 8722 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.18 1.05 – 1.33 0.00712 309 2487 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.29 1.08 – 1.54 0.00567 139 1193 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.23 0.895 – 1.69 0.201 50 359 exclusion phecode
480.13 MRSA pneumonia Respiratory 1.45 0.885 – 2.39 0.139 20 272 exclusion phecode
480.2 Viral pneumonia Respiratory 1.43 1.03 – 2 0.035 41 379 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.44 1.05 – 1.96 0.0231 47 332 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.29 0.912 – 1.83 0.149 39 297 exclusion phecode
481 Influenza Respiratory 0.996 0.879 – 1.13 0.947 298 3205 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 1 0.922 – 1.09 0.946 646 7069 exclusion phecode
495 Asthma Respiratory 1.07 1.01 – 1.13 0.0175 1770 8173 exclusion phecode
495.1 Chronic obstructive asthma Respiratory 1.21 0.939 – 1.57 0.139 66 857 exclusion phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 0.837 0.392 – 1.79 0.647 8 159 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.04 0.927 – 1.17 0.483 321 4419 exclusion phecode
496 Chronic airway obstruction Respiratory 1.31 1.22 – 1.4 2.33e-15 1192 6161 exclusion phecode
496.1 Emphysema Respiratory 1.39 1.27 – 1.53 5.99e-12 559 3825 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.38 1.27 – 1.49 5.46e-16 840 5653 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.41 1.3 – 1.52 1.09e-16 770 5285 exclusion phecode
496.3 Bronchiectasis Respiratory 1.19 1 – 1.41 0.0455 170 1143 exclusion phecode
497 Bronchitis Respiratory 1.07 0.958 – 1.2 0.228 365 4623 exclusion phecode
498 Acute bronchospasm Respiratory 1.35 1.09 – 1.68 0.00628 97 1271 exclusion phecode
499 Cystic fibrosis Respiratory 1.08 0.802 – 1.45 0.622 57 408 exclusion phecode
500 Lung disease due to external agents Respiratory 1.47 1.2 – 1.81 0.000187 122 1106 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.62 0.984 – 2.66 0.058 23 203 exclusion phecode
500.2 Pneumoconiosis Respiratory 0.959 0.484 – 1.9 0.904 10 121 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.48 1.25 – 1.76 9.06e-06 173 1183 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.01 0.854 – 1.2 0.897 165 1637 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.19 1.01 – 1.41 0.0396 164 1657 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.07 0.875 – 1.3 0.527 126 1197 exclusion phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 0.964 0.733 – 1.27 0.79 66 623 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.05 0.933 – 1.18 0.414 342 3215 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.17 1.07 – 1.27 0.000234 701 5222 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.14 1.05 – 1.24 0.00244 659 5524 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.2 1.08 – 1.32 0.000377 475 4713 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.2 1.11 – 1.29 5.66e-06 808 6265 exclusion phecode
509.1 Respiratory failure Respiratory 1.3 1.17 – 1.45 1.02e-06 427 3812 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.16 1.01 – 1.32 0.0311 269 2349 exclusion phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.16 1.04 – 1.3 0.00834 385 3241 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.26 1.11 – 1.42 0.000224 317 3416 exclusion phecode
510 Other diseases of lung Respiratory 1.08 1.01 – 1.15 0.0221 1194 7846 exclusion phecode
510.2 Lung transplant Respiratory 1.26 0.92 – 1.72 0.15 51 373 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.11 1.07 – 1.16 7.26e-07 3890 7132 exclusion phecode
512.1 Wheezing Respiratory 1.2 1.04 – 1.38 0.0146 215 3292 exclusion phecode
512.2 Painful respiration Respiratory 1.11 1.01 – 1.22 0.0274 552 5258 exclusion phecode
512.3 Abnormal chest sounds Respiratory 1.21 0.939 – 1.56 0.141 73 608 exclusion phecode
512.7 Shortness of breath Respiratory 1.15 1.09 – 1.22 1.94e-07 1926 7104 exclusion phecode
512.8 Cough Respiratory 1.08 1.02 – 1.14 0.00462 2033 7127 exclusion phecode
512.9 Other dyspnea Respiratory 1.12 1.06 – 1.18 4.67e-05 1997 7106 exclusion phecode
513 Respiratory abnormalities Respiratory 1.13 1.07 – 1.18 1.1e-06 2470 8537 exclusion phecode
513.3 Hypoventilation Respiratory 1.1 0.914 – 1.32 0.315 128 1878 exclusion phecode
513.31 Apnea Respiratory 1.03 0.81 – 1.3 0.824 76 960 exclusion phecode
513.32 Orthopnea Respiratory 1.24 0.847 – 1.82 0.267 28 412 exclusion phecode
513.4 Hyperventilation Respiratory 1.32 1.06 – 1.66 0.0152 94 1120 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.17 0.848 – 1.62 0.338 40 488 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.13 1.06 – 1.21 0.000123 1193 7434 exclusion phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 0.818 0.611 – 1.1 0.178 52 543 exclusion phecode
514.2 Solitary pulmonary nodule Respiratory 1.09 1.01 – 1.19 0.0366 652 5644 exclusion phecode
516 Abnormal sputum Respiratory 1.22 1.04 – 1.44 0.0162 169 1494 exclusion phecode
516.1 Hemoptysis Respiratory 1.2 1 – 1.44 0.0442 137 1263 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.1 1.04 – 1.17 0.0011 1418 9074 exclusion phecode
519.1 Tracheostomy complications Respiratory 1.53 1.17 – 2.01 0.0019 64 431 exclusion phecode
519.2 Respiratory complications Respiratory 1.05 0.851 – 1.3 0.647 94 928 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.07 0.957 – 1.19 0.237 382 3472 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.14 1.06 – 1.21 0.000255 1037 7618 exclusion phecode
520 Disorders of tooth development Digestive 0.982 0.812 – 1.19 0.855 120 952 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.2 0.873 – 1.64 0.265 52 380 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.935 0.744 – 1.17 0.564 77 638 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.46 1.28 – 1.68 5e-08 250 1935 exclusion phecode
521.1 Dental caries Digestive 1.45 1.26 – 1.67 3.25e-07 234 1781 exclusion phecode
521.2 Dental abrasion, erosion and attrition Digestive 0.929 0.485 – 1.78 0.823 8 116 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.26 1.04 – 1.53 0.0205 111 1178 exclusion phecode
522.5 Periapical abscess Digestive 1.36 1.1 – 1.68 0.00443 95 1040 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.23 1.04 – 1.45 0.0178 163 1547 exclusion phecode
523.1 Gingivitis Digestive 1.06 0.748 – 1.5 0.742 38 340 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.52 1.17 – 1.96 0.00142 71 779 exclusion phecode
523.31 Acute periodontitis Digestive 1.53 1.16 – 2.01 0.00258 56 663 exclusion phecode
523.32 Chronic periodontitis Digestive 1.45 0.963 – 2.18 0.075 30 246 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.02 0.848 – 1.22 0.858 160 1055 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.988 0.796 – 1.22 0.91 110 683 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.34 1.18 – 1.52 7.41e-06 278 2423 exclusion phecode
525.1 Loss of teeth or edentulism Digestive 1.41 1.14 – 1.75 0.00163 105 894 exclusion phecode
526 Diseases of the jaws Digestive 1.05 0.975 – 1.14 0.189 817 6561 exclusion phecode
526.1 Cysts of the jaws Digestive 0.755 0.574 – 0.994 0.045 53 512 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.953 0.778 – 1.17 0.643 123 786 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.01 0.911 – 1.12 0.865 453 3884 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.984 0.879 – 1.1 0.777 371 3116 exclusion phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 1.01 0.879 – 1.17 0.864 237 2005 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 1.38 1.09 – 1.73 0.00635 104 654 exclusion phecode
526.8 Exostosis of jaw Digestive 1.28 0.779 – 2.1 0.332 21 98 exclusion phecode
526.9 Jaw disease NOS Digestive 1.09 0.925 – 1.29 0.294 173 1118 exclusion phecode
527 Diseases of the salivary glands Digestive 1.08 0.973 – 1.2 0.146 425 3834 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 0.937 0.542 – 1.62 0.817 14 141 exclusion phecode
527.2 Sialoadenitis Digestive 1.1 0.883 – 1.38 0.384 95 913 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.2 1.04 – 1.38 0.0149 226 1880 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 0.97 0.716 – 1.31 0.844 54 529 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.07 0.988 – 1.16 0.0955 751 5899 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.08 0.928 – 1.27 0.309 200 1559 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.11 0.822 – 1.5 0.494 51 490 exclusion phecode
528.12 Oral aphthae Digestive 0.893 0.691 – 1.15 0.389 69 559 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.72 1.33 – 2.22 3.06e-05 74 528 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.808 0.545 – 1.2 0.29 33 296 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.908 0.55 – 1.5 0.705 23 176 exclusion phecode
528.5 Diseases of lips Digestive 1.02 0.847 – 1.23 0.819 142 1063 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.13 0.78 – 1.64 0.515 34 277 exclusion phecode
528.7 Sialolithiasis Digestive 1.27 0.908 – 1.78 0.162 44 339 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.04 0.875 – 1.23 0.667 156 1409 exclusion phecode
529.1 Glossitis Digestive 1.28 0.859 – 1.9 0.228 30 268 exclusion phecode
529.6 Glossodynia Digestive 0.859 0.584 – 1.26 0.438 30 321 exclusion phecode
530 Diseases of esophagus Digestive 1.12 1.07 – 1.17 6.04e-07 3202 7330 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.12 1.07 – 1.17 2.23e-06 3046 7330 exclusion phecode
530.11 GERD Digestive 1.11 1.06 – 1.17 5.48e-06 2914 7329 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.15 0.906 – 1.45 0.254 84 907 exclusion phecode
530.13 Barrett's esophagus Digestive 1.31 1.07 – 1.61 0.00938 106 1472 exclusion phecode
530.14 Reflux esophagitis Digestive 1.16 1.04 – 1.3 0.00951 367 4224 exclusion phecode
530.15 Eosinophilic esophagitis Digestive 1.06 0.784 – 1.44 0.699 49 627 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.21 1.01 – 1.45 0.0409 137 1353 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1.24 1.07 – 1.43 0.00466 217 2006 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.19 0.981 – 1.43 0.0784 131 1344 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1 0.707 – 1.42 0.996 43 257 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.78 1.14 – 2.79 0.0113 22 185 exclusion phecode
530.9 Heartburn Digestive 1.11 0.98 – 1.26 0.0998 300 3782 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.17 1.05 – 1.29 0.00305 435 4455 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.12 0.881 – 1.42 0.358 81 733 exclusion phecode
531.2 Gastric ulcer Digestive 1.27 1.11 – 1.46 0.00046 247 2646 exclusion phecode
531.3 Duodenal ulcer Digestive 1.12 0.909 – 1.37 0.296 99 883 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.07 0.907 – 1.26 0.431 180 1724 exclusion phecode
531.5 Gastrojejunal ulcer Digestive 1.02 0.72 – 1.44 0.917 38 323 exclusion phecode
532 Dysphagia Digestive 1.26 1.18 – 1.34 3.94e-13 1388 6859 exclusion phecode
535 Gastritis and duodenitis Digestive 1.05 0.964 – 1.15 0.257 611 6299 exclusion phecode
535.1 Acute gastritis Digestive 1.23 1.08 – 1.41 0.00226 238 2623 exclusion phecode
535.2 Atrophic gastritis Digestive 0.943 0.741 – 1.2 0.636 76 786 exclusion phecode
535.6 Duodenitis Digestive 0.828 0.636 – 1.08 0.16 67 710 exclusion phecode
535.8 Other specified gastritis Digestive 1.03 0.869 – 1.23 0.709 142 1439 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.02 0.899 – 1.15 0.784 294 2905 exclusion phecode
536 Disorders of function of stomach Digestive 1.14 1.05 – 1.23 0.00102 771 6521 exclusion phecode
536.3 Gastroparesis Digestive 1.25 1.06 – 1.47 0.00677 184 1584 exclusion phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.32 1.1 – 1.59 0.00302 137 858 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.11 1.01 – 1.22 0.0292 544 4961 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.12 1.04 – 1.21 0.00431 746 6762 exclusion phecode
537.1 Lesions of stomach and duodenum Digestive 1.47 1.03 – 2.1 0.0358 34 309 exclusion phecode
539 Bariatric surgery Digestive 2.33 1.81 – 2.98 3.18e-11 73 3739 exclusion phecode
540 Appendiceal conditions Digestive 0.918 0.759 – 1.11 0.379 126 1222 exclusion phecode
540.1 Appendicitis Digestive 0.841 0.685 – 1.03 0.0988 110 1037 exclusion phecode
540.11 Acute appendicitis Digestive 0.824 0.66 – 1.03 0.0864 95 855 exclusion phecode
550 Abdominal hernia Digestive 0.996 0.934 – 1.06 0.892 1207 8816 exclusion phecode
550.1 Inguinal hernia Digestive 0.874 0.788 – 0.969 0.0108 445 3017 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.09 0.988 – 1.21 0.0839 446 5737 exclusion phecode
550.3 Femoral hernia Digestive 0.824 0.6 – 1.13 0.233 51 272 exclusion phecode
550.4 Umbilical hernia Digestive 0.933 0.79 – 1.1 0.417 155 2658 exclusion phecode
550.5 Ventral hernia Digestive 1.05 0.933 – 1.17 0.443 340 4744 exclusion phecode
550.6 Incisional hernia Digestive 1.11 0.952 – 1.3 0.181 177 2826 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.11 1.01 – 1.23 0.0357 466 3704 exclusion phecode
555.1 Regional enteritis Digestive 1.21 1.07 – 1.37 0.00219 313 2269 exclusion phecode
555.2 Ulcerative colitis Digestive 1.04 0.911 – 1.19 0.559 273 2180 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 0.981 0.832 – 1.16 0.82 175 1300 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.19 1 – 1.41 0.0482 159 1371 exclusion phecode
556.1 Ulceration of intestine Digestive 1.16 0.965 – 1.39 0.115 139 1217 exclusion phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 1.22 0.856 – 1.73 0.275 40 393 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.19 1.07 – 1.33 0.00184 381 4374 exclusion phecode
557.1 Celiac disease Digestive 1.1 0.918 – 1.31 0.305 155 1065 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.14 1.06 – 1.23 0.000535 893 6442 exclusion phecode
559 Ileostomy status Digestive 1.21 1.06 – 1.39 0.00568 248 2053 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.18 1.09 – 1.28 3.19e-05 792 5625 exclusion phecode
560.1 Paralytic ileus Digestive 1.16 1.04 – 1.3 0.00789 385 3274 exclusion phecode
560.2 Impaction of intestine Digestive 1.25 1.01 – 1.55 0.0393 111 930 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.18 0.934 – 1.5 0.164 90 613 exclusion phecode
560.4 Other intestinal obstruction Digestive 1.23 1.11 – 1.36 6.71e-05 482 3597 exclusion phecode
561 Symptoms involving digestive system Digestive 1.12 1.03 – 1.22 0.00876 672 5257 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1.03 0.956 – 1.11 0.444 1035 4936 exclusion phecode
562.1 Diverticulosis Digestive 1.02 0.95 – 1.1 0.557 1026 4925 exclusion phecode
562.2 Diverticulitis Digestive 1.16 1.01 – 1.32 0.0367 249 3143 exclusion phecode
564 Functional digestive disorders Digestive 1.11 1.06 – 1.17 7.29e-06 2747 6964 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.09 1.01 – 1.17 0.024 904 5634 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.13 1.04 – 1.22 0.00523 685 5931 exclusion phecode
565 Anal and rectal conditions Digestive 1 0.929 – 1.08 0.958 818 6940 exclusion phecode
565.1 Anal and rectal polyp Digestive 0.913 0.794 – 1.05 0.201 236 2505 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.24 1.1 – 1.39 0.000488 336 2915 exclusion phecode
568 Other disorders of peritoneum Digestive 1.09 0.98 – 1.22 0.111 372 3676 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.16 1.02 – 1.33 0.0256 262 2676 exclusion phecode
569 Other disorders of intestine Digestive 1.09 1.03 – 1.15 0.00215 1700 8326 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.2 0.936 – 1.55 0.148 81 697 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.23 1.09 – 1.38 0.000968 304 3101 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.17 1.08 – 1.27 0.000137 692 7454 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.15 1.06 – 1.25 0.00108 622 7333 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.23 1.05 – 1.44 0.00936 178 1964 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.44 1.03 – 2.01 0.0345 38 370 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.23 1.06 – 1.44 0.00716 201 1842 exclusion phecode
571.81 Portal hypertension Digestive 1.21 0.979 – 1.48 0.078 106 1127 exclusion phecode
572 Ascites (non malignant) Digestive 1.16 1.06 – 1.27 0.00126 575 5073 exclusion phecode
573 Other disorders of liver Digestive 1.07 1 – 1.15 0.0389 1049 7805 exclusion phecode
573.1 Chronic passive congestion of liver Digestive 1.75 1.15 – 2.64 0.00866 33 296 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.2 0.934 – 1.55 0.152 71 550 exclusion phecode
573.3 Hepatomegaly Digestive 1.33 1.07 – 1.66 0.0102 93 1082 exclusion phecode
573.4 Acute and subacute necrosis of liver Digestive 1.22 0.952 – 1.56 0.116 80 635 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.22 1.06 – 1.4 0.00547 232 1937 exclusion phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.15 1.05 – 1.26 0.00215 560 5842 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.1 1.01 – 1.21 0.0296 572 6092 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.16 1.08 – 1.24 2.97e-05 969 7954 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.15 1.04 – 1.26 0.00435 520 7209 exclusion phecode
574.1 Cholelithiasis Digestive 1.13 1.02 – 1.25 0.0157 455 6806 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1 0.752 – 1.34 0.981 46 772 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.975 0.768 – 1.24 0.834 77 1290 exclusion phecode
574.2 Calculus of bile duct Digestive 1.08 0.908 – 1.28 0.392 161 1979 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.26 1.05 – 1.52 0.0117 137 1871 exclusion phecode
575 Other biliary tract disease Digestive 1.16 1.05 – 1.27 0.00319 496 5142 exclusion phecode
575.1 Cholangitis Digestive 1.27 1.02 – 1.57 0.029 101 731 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.32 1.11 – 1.56 0.00123 173 1349 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.722 0.519 – 1.01 0.0537 40 529 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.2 1.02 – 1.42 0.0256 170 2192 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.21 1.07 – 1.36 0.00302 302 2508 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.864 0.654 – 1.14 0.306 56 590 exclusion phecode
577 Diseases of pancreas Digestive 1.16 1.06 – 1.27 0.00168 554 4716 exclusion phecode
577.1 Acute pancreatitis Digestive 1.27 1.12 – 1.45 0.000194 285 2551 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.56 1.29 – 1.89 4.04e-06 138 982 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.07 0.897 – 1.29 0.438 158 1167 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.05 0.985 – 1.13 0.125 1007 8632 exclusion phecode
578.1 Hematemesis Digestive 1.2 0.988 – 1.46 0.0661 117 1060 exclusion phecode
578.2 Blood in stool Digestive 1.09 0.994 – 1.19 0.0689 600 5938 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 0.993 0.901 – 1.1 0.892 476 5034 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.1 0.978 – 1.23 0.114 349 3224 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.07 1 – 1.15 0.0423 975 7967 exclusion phecode
579.2 Splenomegaly Digestive 1.21 1 – 1.47 0.0495 121 1577 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.03 0.92 – 1.16 0.572 326 3092 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.29 1.14 – 1.45 4.23e-05 327 3423 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.43 1.13 – 1.81 0.00305 93 846 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.42 0.959 – 2.1 0.0802 30 314 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.7 1.03 – 2.8 0.0397 17 241 exclusion phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.57 0.885 – 2.79 0.123 13 135 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.49 1.13 – 1.96 0.00433 71 621 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.13 0.81 – 1.57 0.478 37 466 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.36 1.18 – 1.56 1.36e-05 249 2607 exclusion phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.29 1.08 – 1.56 0.00576 138 1500 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.48 1.24 – 1.76 1.18e-05 147 1449 exclusion phecode
580.4 Renal sclerosis, NOS Genitourinary 1.18 0.922 – 1.51 0.19 71 754 exclusion phecode
585 Renal failure Genitourinary 1.21 1.14 – 1.29 1.07e-09 1352 7675 exclusion phecode
585.1 Acute renal failure Genitourinary 1.28 1.18 – 1.38 5.94e-10 803 6037 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.3 1.1 – 1.53 0.00185 182 1711 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.21 1.13 – 1.3 1.53e-07 985 6716 exclusion phecode
585.31 Renal dialysis Genitourinary 1.33 1.13 – 1.57 0.000656 176 1530 exclusion phecode
585.32 End stage renal disease Genitourinary 1.45 1.26 – 1.67 3.07e-07 238 2054 exclusion phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.23 1.12 – 1.36 2.92e-05 492 4489 exclusion phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.32 1.13 – 1.54 0.000544 187 1901 exclusion phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.26 1.09 – 1.45 0.00174 232 2389 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.12 1.06 – 1.19 0.00015 1476 8474 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.1 0.879 – 1.38 0.397 86 891 exclusion phecode
586.11 Small kidney Genitourinary 1.1 0.811 – 1.49 0.538 45 515 exclusion phecode
586.12 Vesicoureteral reflux Genitourinary 1.02 0.753 – 1.39 0.876 40 401 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.08 0.948 – 1.23 0.241 257 2645 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.25 0.904 – 1.73 0.178 44 391 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.07 0.959 – 1.19 0.227 391 3829 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.34 1.16 – 1.54 7.09e-05 231 1742 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.41 1.21 – 1.63 5.52e-06 220 2000 exclusion phecode
588.1 Renal osteodystrophy Genitourinary 1.35 1.07 – 1.72 0.0131 85 582 exclusion phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.34 1.13 – 1.59 8e-04 155 1556 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.19 1.03 – 1.39 0.0225 210 2132 exclusion phecode
590 Pyelonephritis Genitourinary 1.11 0.986 – 1.25 0.0844 326 3559 exclusion phecode
591 Urinary tract infection Genitourinary 1.01 0.959 – 1.06 0.745 2300 7506 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.05 0.97 – 1.14 0.225 740 5943 exclusion phecode
592.1 Cystitis Genitourinary 1.06 0.977 – 1.15 0.161 698 5747 exclusion phecode
592.11 Acute cystitis Genitourinary 1.07 0.964 – 1.19 0.197 421 4051 exclusion phecode
592.12 Chronic cystitis Genitourinary 1.1 0.812 – 1.49 0.541 49 587 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.05 0.871 – 1.26 0.619 139 1166 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.04 0.778 – 1.38 0.812 62 490 exclusion phecode
593 Hematuria Genitourinary 1.01 0.937 – 1.08 0.871 970 7381 exclusion phecode
593.1 Gross hematuria Genitourinary 1.01 0.894 – 1.15 0.824 285 2873 exclusion phecode
593.2 Microscopic hematuria Genitourinary 1.02 0.881 – 1.18 0.803 229 2282 exclusion phecode
594 Urinary calculus Genitourinary 1.08 1.01 – 1.15 0.016 1206 9137 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.07 1 – 1.14 0.0381 1117 9085 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.17 0.923 – 1.47 0.198 80 715 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.03 0.902 – 1.18 0.638 234 3001 exclusion phecode
594.8 Renal colic Genitourinary 1.22 0.956 – 1.56 0.11 70 882 exclusion phecode
595 Hydronephrosis Genitourinary 1.18 1.06 – 1.32 0.00294 382 3817 exclusion phecode
596 Other disorders of bladder Genitourinary 0.981 0.902 – 1.07 0.645 673 5962 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.11 0.875 – 1.42 0.382 75 680 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 0.995 0.891 – 1.11 0.932 381 3817 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.01 0.885 – 1.15 0.905 278 2509 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.969 0.802 – 1.17 0.746 129 1171 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.01 0.876 – 1.17 0.846 217 2148 exclusion phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.19 0.859 – 1.65 0.296 40 454 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.94 1.21 – 3.11 0.00631 25 281 exclusion phecode
598.4 Other cells and casts in urine Genitourinary 1.69 1.05 – 2.73 0.0305 23 247 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.988 0.944 – 1.03 0.585 3011 7568 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.86 0.711 – 1.04 0.119 132 1245 exclusion phecode
599.2 Retention of urine Genitourinary 1.01 0.946 – 1.09 0.681 1038 6664 exclusion phecode
599.3 Dysuria Genitourinary 0.968 0.904 – 1.04 0.353 1049 6736 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.969 0.902 – 1.04 0.397 972 6365 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 0.967 0.903 – 1.03 0.328 1105 6871 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.16 0.969 – 1.4 0.105 142 1204 exclusion phecode
599.7 Urethral discharge Genitourinary 1.09 0.684 – 1.73 0.725 18 194 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 0.955 0.892 – 1.02 0.183 1114 6590 exclusion phecode
599.9 Other abnormality of urination Genitourinary 0.934 0.856 – 1.02 0.126 621 5727 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.904 0.817 – 0.999 0.0481 641 1750 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 0.932 0.786 – 1.11 0.421 157 1631 exclusion phecode
601.1 Prostatitis Genitourinary 0.873 0.679 – 1.12 0.288 76 724 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.798 0.531 – 1.2 0.28 31 199 exclusion phecode
601.12 Chronic prostatitis Genitourinary 0.881 0.46 – 1.69 0.702 12 142 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.96 0.737 – 1.25 0.761 61 681 exclusion phecode
601.4 Balanoposthitis Genitourinary 1.29 0.755 – 2.21 0.351 13 226 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.897 0.598 – 1.35 0.601 23 286 exclusion phecode
602 Other disorders of prostate Genitourinary 1.01 0.771 – 1.34 0.919 67 483 exclusion phecode
602.3 Dysplasia of prostate Genitourinary 1.24 0.659 – 2.32 0.51 15 93 exclusion phecode
603 Other disorders of testis Genitourinary 1.12 0.902 – 1.4 0.299 86 836 exclusion phecode
603.1 Hydrocele Genitourinary 1.03 0.769 – 1.37 0.851 47 521 exclusion phecode
603.2 Spermatocele Genitourinary 1.11 0.79 – 1.55 0.559 40 283 exclusion phecode
604 Disorders of penis Genitourinary 0.991 0.828 – 1.19 0.924 133 1209 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.29 0.814 – 2.05 0.278 16 263 exclusion phecode
604.3 Peyronie's disease Genitourinary 0.957 0.704 – 1.3 0.777 48 330 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.902 0.815 – 0.999 0.048 496 2198 exclusion phecode
608 Other disorders of male genital organs Genitourinary 0.956 0.849 – 1.08 0.458 317 2629 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.924 0.732 – 1.16 0.501 77 860 exclusion phecode
609.1 Infertility, male Genitourinary 0.939 0.721 – 1.22 0.64 56 653 exclusion phecode
609.11 Azoospermia and oligospermia Genitourinary 1.31 0.805 – 2.12 0.279 14 230 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.798 0.519 – 1.23 0.303 24 295 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.9 0.839 – 0.966 0.00345 1103 4593 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.891 0.807 – 0.984 0.0229 506 3675 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 0.631 0.378 – 1.06 0.0793 19 147 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.905 0.837 – 0.977 0.011 879 4543 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.897 0.802 – 1 0.0568 390 3126 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.895 0.844 – 0.948 0.000186 1789 4939 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.874 0.82 – 0.932 3.55e-05 1489 4263 exclusion phecode
611.11 Mammographic microcalcification Genitourinary 0.871 0.774 – 0.979 0.0208 364 2535 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.903 0.841 – 0.968 0.00423 1089 4931 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.828 0.718 – 0.954 0.00901 232 2773 exclusion phecode
612.1 Galactorrhea Genitourinary 0.741 0.508 – 1.08 0.121 34 435 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.931 0.777 – 1.12 0.442 135 2033 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 0.483 0.316 – 0.737 0.000753 36 230 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.939 0.878 – 1 0.068 1132 5978 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 0.896 0.757 – 1.06 0.2 152 1564 exclusion phecode
613.5 Mastodynia Genitourinary 1 0.908 – 1.11 0.959 489 4210 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.872 0.764 – 0.996 0.0429 269 2329 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 0.873 0.767 – 0.995 0.0413 273 2469 exclusion phecode
613.9 Breast disorder NOS Genitourinary 0.916 0.824 – 1.02 0.105 424 3595 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.994 0.928 – 1.07 0.875 1089 5485 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.968 0.763 – 1.23 0.79 84 897 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1 0.834 – 1.2 0.988 140 1356 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.989 0.667 – 1.47 0.956 31 282 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.909 0.686 – 1.2 0.507 61 500 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.917 0.714 – 1.18 0.498 72 687 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.952 0.698 – 1.3 0.754 52 476 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.984 0.914 – 1.06 0.666 944 5450 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.07 0.827 – 1.37 0.624 71 767 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.986 0.912 – 1.07 0.727 820 5315 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.17 0.813 – 1.7 0.393 37 368 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.849 0.641 – 1.12 0.253 59 631 exclusion phecode
615 Endometriosis Genitourinary 1.04 0.937 – 1.15 0.462 433 3999 exclusion phecode
618 Genital prolapse Genitourinary 0.99 0.898 – 1.09 0.846 508 4723 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.962 0.855 – 1.08 0.519 345 3445 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.982 0.821 – 1.18 0.845 145 1379 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.967 0.746 – 1.25 0.798 73 757 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.02 0.821 – 1.26 0.866 103 1118 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1.01 0.948 – 1.07 0.865 1658 5216 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.926 0.823 – 1.04 0.202 344 3480 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 0.993 0.836 – 1.18 0.934 154 1622 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.932 0.786 – 1.11 0.418 163 1311 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.01 0.93 – 1.09 0.849 760 5121 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.02 0.905 – 1.15 0.743 326 3206 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1.07 0.88 – 1.3 0.5 118 1063 exclusion phecode
620.1 Dysplasia of cervix Genitourinary 0.979 0.743 – 1.29 0.88 57 513 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.76 0.589 – 0.98 0.0347 63 1163 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.849 0.757 – 0.953 0.00536 353 3805 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.814 0.711 – 0.931 0.00261 258 2965 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 0.859 0.704 – 1.05 0.131 123 1162 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.01 0.871 – 1.17 0.914 220 2246 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 1.05 0.941 – 1.16 0.406 437 3600 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 1.07 0.807 – 1.42 0.632 55 525 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 1.46 0.93 – 2.31 0.0999 28 159 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.925 0.828 – 1.03 0.169 388 3990 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.982 0.925 – 1.04 0.537 1668 4852 exclusion phecode
625.1 Dyspareunia Genitourinary 0.963 0.863 – 1.07 0.497 405 3480 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.959 0.903 – 1.02 0.177 1676 4395 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.936 0.875 – 1 0.0596 1227 4097 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 1.05 0.925 – 1.19 0.449 304 2629 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 0.928 0.844 – 1.02 0.123 547 3486 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.934 0.848 – 1.03 0.158 552 3582 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.914 0.802 – 1.04 0.18 278 2647 exclusion phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.806 0.657 – 0.988 0.038 108 1134 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.984 0.882 – 1.1 0.77 408 3005 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.937 0.75 – 1.17 0.567 99 955 exclusion phecode
626.8 Infertility, female Genitourinary 0.903 0.788 – 1.03 0.14 255 2068 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.92 0.859 – 0.986 0.0179 1243 3886 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 0.866 0.759 – 0.989 0.0338 277 2549 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.93 0.858 – 1.01 0.0785 834 3588 exclusion phecode
627.21 Symptomatic artificial menopause Genitourinary 0.719 0.493 – 1.05 0.0863 40 402 exclusion phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.844 0.683 – 1.04 0.115 113 855 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.867 0.764 – 0.985 0.0281 314 2315 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 0.972 0.773 – 1.22 0.81 91 963 exclusion phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.958 0.784 – 1.17 0.672 118 838 exclusion phecode
628 Ovarian cyst Genitourinary 0.93 0.845 – 1.02 0.136 539 3925 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.03 0.894 – 1.18 0.72 244 2293 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.903 0.717 – 1.14 0.387 90 772 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.84 0.579 – 1.22 0.359 30 347 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.904 0.768 – 1.06 0.226 183 1632 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.896 0.734 – 1.09 0.28 122 1112 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.907 0.719 – 1.14 0.41 88 909 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.95 0.845 – 1.07 0.383 351 2386 exclusion phecode
636.1 Threatened premature labor Pregnancy Complications 1.05 0.869 – 1.27 0.607 131 1173 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 1.06 0.839 – 1.34 0.625 92 869 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.913 0.759 – 1.1 0.334 132 1359 exclusion phecode
636.8 Cervical incompetence Pregnancy Complications 1.29 0.811 – 2.04 0.286 22 245 exclusion phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.2 0.76 – 1.89 0.436 20 240 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.903 0.75 – 1.09 0.284 129 1768 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.963 0.743 – 1.25 0.776 66 885 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.02 0.787 – 1.31 0.903 71 800 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.851 0.595 – 1.22 0.378 35 368 exclusion phecode
644 Anemia during pregnancy Pregnancy Complications 0.966 0.746 – 1.25 0.796 69 747 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.995 0.862 – 1.15 0.944 227 2138 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.09 0.842 – 1.4 0.524 75 655 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.908 0.688 – 1.2 0.496 63 712 exclusion phecode
647.3 Major puerperal infection Pregnancy Complications 0.855 0.513 – 1.43 0.55 20 204 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.978 0.87 – 1.1 0.705 367 2532 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.963 0.794 – 1.17 0.7 124 1610 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.05 0.884 – 1.24 0.587 163 1713 exclusion phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.929 0.694 – 1.24 0.622 54 637 exclusion phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 0.846 0.647 – 1.11 0.223 65 637 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.925 0.838 – 1.02 0.121 514 3055 exclusion phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 0.927 0.79 – 1.09 0.355 188 1757 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.962 0.84 – 1.1 0.576 253 2170 exclusion phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 0.819 0.394 – 1.71 0.594 5 144 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.947 0.828 – 1.08 0.432 266 2143 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.13 0.855 – 1.48 0.4 64 707 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.887 0.635 – 1.24 0.484 44 543 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.711 0.537 – 0.942 0.0173 63 580 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.18 1.11 – 1.26 5.47e-08 1331 9223 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.06 0.929 – 1.21 0.386 259 2612 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.25 1.08 – 1.44 0.00255 224 2219 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.25 1.12 – 1.39 4.51e-05 397 4472 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.22 1.09 – 1.35 0.000284 406 4641 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.3 1.16 – 1.46 1.32e-05 330 3685 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.18 1.04 – 1.34 0.0103 285 3560 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.07 0.971 – 1.18 0.173 485 4893 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 0.999 0.822 – 1.22 0.995 114 1391 exclusion phecode
686.2 Impetigo Dermatologic 1.07 0.858 – 1.33 0.55 102 1017 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.21 0.832 – 1.76 0.317 28 403 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 0.962 0.667 – 1.39 0.838 34 380 exclusion phecode
686.5 Pyoderma Dermatologic 1.72 0.823 – 3.58 0.15 8 144 exclusion phecode
687 Symptoms affecting skin Dermatologic 0.959 0.864 – 1.06 0.426 449 3752 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.991 0.937 – 1.05 0.753 1623 8190 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.95 0.748 – 1.21 0.674 85 837 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.02 0.961 – 1.08 0.504 1359 8010 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.922 0.877 – 0.968 0.00125 2241 8716 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.888 0.831 – 0.948 0.000377 1200 6764 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.887 0.831 – 0.948 0.000364 1200 6752 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.946 0.784 – 1.14 0.565 123 1322 exclusion phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 1.34 0.847 – 2.12 0.211 21 163 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.893 0.81 – 0.984 0.0223 500 4084 exclusion phecode
694.1 Vitiligo Dermatologic 1.23 0.857 – 1.75 0.265 37 300 exclusion phecode
694.2 Other dyschromia Dermatologic 0.866 0.782 – 0.96 0.00618 447 3711 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.32 0.836 – 2.08 0.234 24 163 exclusion phecode
695 Erythematous conditions Dermatologic 0.983 0.911 – 1.06 0.651 844 6904 exclusion phecode
695.1 Toxic erythema Dermatologic 0.828 0.467 – 1.47 0.518 15 173 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.28 0.748 – 2.18 0.372 20 172 exclusion phecode
695.3 Rosacea Dermatologic 0.815 0.728 – 0.912 0.00036 366 3953 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.24 1.05 – 1.46 0.0108 185 1711 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.21 0.927 – 1.59 0.159 67 616 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.23 1.04 – 1.45 0.0145 177 1613 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 1.13 0.93 – 1.38 0.214 113 1324 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 0.948 0.775 – 1.16 0.606 105 1866 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.724 0.427 – 1.23 0.23 15 165 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.09 0.913 – 1.31 0.335 132 1504 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.904 0.796 – 1.03 0.115 275 3123 exclusion phecode
696.3 Pityriasis Dermatologic 0.75 0.521 – 1.08 0.123 36 277 exclusion phecode
696.4 Psoriasis Dermatologic 0.944 0.823 – 1.08 0.406 238 2876 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.923 0.801 – 1.06 0.262 222 2603 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.733 0.523 – 1.03 0.0701 41 615 exclusion phecode
697 Sarcoidosis Dermatologic 1.19 0.881 – 1.6 0.261 47 653 exclusion phecode
698 Pruritus and related conditions Dermatologic 0.947 0.864 – 1.04 0.241 557 5421 exclusion phecode
700 Corns and callosities Dermatologic 0.993 0.861 – 1.15 0.924 229 2355 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.941 0.891 – 0.994 0.0296 1735 9024 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.994 0.829 – 1.19 0.951 141 1181 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.971 0.89 – 1.06 0.501 623 5144 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.986 0.816 – 1.19 0.883 133 1404 exclusion phecode
701.4 Keloid scar Dermatologic 0.879 0.741 – 1.04 0.137 158 1531 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 0.998 0.798 – 1.25 0.983 91 904 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.878 0.826 – 0.932 1.93e-05 1588 6196 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.836 0.776 – 0.9 2.18e-06 950 5238 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.885 0.83 – 0.944 0.000201 1277 6486 exclusion phecode
702.4 Degenerative skin disorders Dermatologic 1.39 0.863 – 2.25 0.175 25 197 exclusion phecode
703 Diseases of nail, NOS Dermatologic 0.938 0.832 – 1.06 0.289 333 3307 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.929 0.788 – 1.1 0.382 167 1978 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.971 0.899 – 1.05 0.463 765 7325 exclusion phecode
704.1 Alopecia Dermatologic 0.909 0.817 – 1.01 0.0784 409 3630 exclusion phecode
704.11 Alopecia Areata Dermatologic 1.35 0.817 – 2.22 0.243 21 179 exclusion phecode
704.12 Telogen effluvium Dermatologic 0.833 0.514 – 1.35 0.456 22 160 exclusion phecode
704.2 Hirsutism Dermatologic 1.08 0.795 – 1.48 0.613 45 882 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.05 0.937 – 1.17 0.425 375 3901 exclusion phecode
705 Disorders of sweat glands Dermatologic 0.989 0.819 – 1.19 0.908 115 1541 exclusion phecode
705.1 Dyshidrosis Dermatologic 0.716 0.479 – 1.07 0.103 33 340 exclusion phecode
705.3 Hidradenitis Dermatologic 1.16 0.835 – 1.62 0.372 33 639 exclusion phecode
705.8 Hyperhidrosis Dermatologic 0.989 0.868 – 1.13 0.873 263 2649 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 0.895 0.845 – 0.947 0.000132 1531 9248 exclusion phecode
706.1 Acne Dermatologic 0.864 0.801 – 0.932 0.000146 832 5978 exclusion phecode
706.2 Sebaceous cyst Dermatologic 0.907 0.833 – 0.987 0.0242 644 6019 exclusion phecode
706.3 Seborrhea Dermatologic 0.527 0.298 – 0.931 0.0275 16 137 exclusion phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.943 0.835 – 1.06 0.343 322 3244 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.21 1.11 – 1.32 1.56e-05 597 5738 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.26 1.08 – 1.46 0.00292 206 1652 exclusion phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.29 1.1 – 1.51 0.0015 180 1928 exclusion phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1.21 1.08 – 1.36 0.000821 356 3547 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.979 0.877 – 1.09 0.711 383 3529 exclusion phecode
709.2 Sicca syndrome Dermatologic 1 0.834 – 1.21 0.971 132 1192 exclusion phecode
709.3 Systemic sclerosis Dermatologic 0.925 0.719 – 1.19 0.545 72 515 exclusion phecode
709.5 Dermatomyositis Dermatologic 0.867 0.548 – 1.37 0.543 18 210 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.21 0.796 – 1.84 0.373 27 213 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.02 0.889 – 1.18 0.742 239 2277 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.22 1.07 – 1.39 0.00239 282 2616 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.22 1.07 – 1.39 0.00265 275 2462 exclusion phecode
710.11 Acute osteomyelitis Musculoskeletal 1.33 1.1 – 1.62 0.00356 130 1196 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.2 0.983 – 1.46 0.0731 126 1049 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.28 1.11 – 1.46 0.00042 258 2362 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 0.819 0.636 – 1.05 0.12 77 883 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.02 0.745 – 1.41 0.88 46 610 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.04 0.733 – 1.47 0.834 31 400 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.15 0.878 – 1.5 0.314 62 642 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.71 1.05 – 2.79 0.0299 20 304 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.16 1.05 – 1.29 0.00407 468 4438 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.22 1.09 – 1.37 0.000468 386 3663 exclusion phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.13 0.772 – 1.66 0.527 33 237 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.06 0.923 – 1.22 0.397 244 2802 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.11 0.838 – 1.48 0.456 57 676 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.05 0.782 – 1.41 0.746 50 545 exclusion phecode
716 Other arthropathies Musculoskeletal 1.04 0.994 – 1.1 0.0858 2506 7939 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.05 0.733 – 1.5 0.79 33 432 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.794 0.511 – 1.23 0.305 20 272 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.04 0.994 – 1.1 0.0829 2492 7936 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.94 0.702 – 1.26 0.678 52 562 exclusion phecode
720 Spinal stenosis Musculoskeletal 1.1 1.01 – 1.19 0.0356 649 6151 exclusion phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1.14 1.03 – 1.26 0.0132 428 4881 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1.08 1.01 – 1.16 0.024 1075 7226 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.08 1.01 – 1.16 0.0277 1008 7068 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.18 0.991 – 1.4 0.0629 152 1737 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 0.986 0.708 – 1.37 0.933 40 562 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.09 1.02 – 1.16 0.00806 1199 8037 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.11 1.03 – 1.21 0.0109 659 7186 exclusion phecode
722.3 Schmorl's nodes Musculoskeletal 0.895 0.616 – 1.3 0.561 32 264 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.09 1 – 1.17 0.0432 752 6798 exclusion phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.38 1.09 – 1.74 0.00728 92 1084 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.21 0.935 – 1.56 0.148 73 827 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.962 0.86 – 1.08 0.502 370 4256 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.01 0.88 – 1.17 0.853 230 2233 exclusion phecode
723.1 Torticollis Musculoskeletal 0.975 0.743 – 1.28 0.856 62 589 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1 0.933 – 1.08 0.914 890 7601 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1 0.913 – 1.1 0.944 520 5376 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.829 0.668 – 1.03 0.0884 98 1021 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.06 0.907 – 1.25 0.446 175 2182 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.07 0.947 – 1.22 0.264 288 3198 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.962 0.914 – 1.01 0.141 2111 7342 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.963 0.909 – 1.02 0.19 1605 7313 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.921 0.783 – 1.08 0.319 173 2098 exclusion phecode
726.3 Bursitis Musculoskeletal 0.908 0.81 – 1.02 0.0954 359 3818 exclusion phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.939 0.815 – 1.08 0.381 228 2653 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1 0.944 – 1.06 0.994 1618 7309 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.03 0.944 – 1.12 0.532 681 6062 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 1.05 0.821 – 1.35 0.685 80 907 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.988 0.879 – 1.11 0.843 347 3217 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 1.06 0.845 – 1.33 0.618 89 1092 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.93 0.838 – 1.03 0.173 420 4585 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.12 0.946 – 1.32 0.192 167 1482 exclusion phecode
727.8 Plica syndrome Musculoskeletal 0.883 0.649 – 1.2 0.427 50 385 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1 0.937 – 1.08 0.895 988 7020 exclusion phecode
728.1 Muscular calcification and ossification Musculoskeletal 1.09 0.696 – 1.71 0.708 22 186 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.05 0.833 – 1.33 0.676 77 712 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.88 0.797 – 0.97 0.0104 473 5331 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.706 0.572 – 0.871 0.00118 108 781 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.11 1.02 – 1.21 0.0116 669 6222 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.27 0.793 – 2.04 0.319 19 168 exclusion phecode
729.3 Panniculitis Musculoskeletal 1.12 0.614 – 2.03 0.716 9 304 exclusion phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 0.947 0.61 – 1.47 0.81 21 155 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.28 0.903 – 1.81 0.166 36 353 exclusion phecode
732 Osteochondropathies Musculoskeletal 1.01 0.807 – 1.26 0.956 91 1000 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.996 0.708 – 1.4 0.983 40 530 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.16 0.743 – 1.81 0.515 24 265 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.964 0.902 – 1.03 0.269 1259 6039 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.16 0.864 – 1.56 0.324 53 452 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.24 1.04 – 1.48 0.0146 160 1061 exclusion phecode
733.6 Costochondritis Musculoskeletal 1.1 0.879 – 1.39 0.397 79 878 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.34 1.15 – 1.55 0.000147 207 1900 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.27 0.848 – 1.9 0.245 33 261 exclusion phecode
735 Acquired foot deformities Musculoskeletal 0.95 0.878 – 1.03 0.201 762 6663 exclusion phecode
735.1 Flat foot Musculoskeletal 0.847 0.693 – 1.04 0.106 109 1399 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 0.961 0.843 – 1.1 0.55 279 2535 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.04 0.873 – 1.24 0.662 160 1562 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.982 0.791 – 1.22 0.873 103 848 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.877 0.78 – 0.985 0.0273 348 3312 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 0.942 0.863 – 1.03 0.179 614 6048 exclusion phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.987 0.661 – 1.47 0.951 32 220 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.04 0.788 – 1.37 0.784 66 463 exclusion phecode
736.3 Acquired deformities of hip Musculoskeletal 0.917 0.53 – 1.59 0.758 16 188 exclusion phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 1.11 0.831 – 1.48 0.485 48 682 exclusion phecode
736.5 Acquired deformities of knee Musculoskeletal 0.971 0.685 – 1.38 0.869 32 499 exclusion phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.916 0.719 – 1.17 0.477 78 779 exclusion phecode
737 Curvature of spine Musculoskeletal 1.04 0.941 – 1.15 0.427 462 3890 exclusion phecode
737.1 Kyphosis (acquired) Musculoskeletal 1.17 0.955 – 1.44 0.129 110 1080 exclusion phecode
737.2 Lordosis (acquired) Musculoskeletal 1.46 0.846 – 2.53 0.173 12 152 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.01 0.907 – 1.13 0.829 386 3060 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.15 1.05 – 1.25 0.00179 631 5535 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.2 1.03 – 1.39 0.0204 198 2157 exclusion phecode
739 Contracture of joint Musculoskeletal 0.997 0.837 – 1.19 0.973 160 1370 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.04 0.991 – 1.09 0.113 2937 7929 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.975 0.911 – 1.04 0.46 1157 6673 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.963 0.896 – 1.03 0.306 1023 6187 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.08 0.896 – 1.31 0.406 122 1668 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.07 0.941 – 1.21 0.311 306 2887 exclusion phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 1.22 0.945 – 1.57 0.127 71 857 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.04 0.993 – 1.09 0.0948 2783 7867 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.02 0.967 – 1.07 0.481 1879 8544 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.904 0.682 – 1.2 0.484 54 599 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.02 0.904 – 1.15 0.769 323 2891 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 1.11 1.01 – 1.22 0.0302 496 4936 exclusion phecode
741.4 Joint effusions Musculoskeletal 0.991 0.905 – 1.09 0.854 540 5845 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.1 0.674 – 1.79 0.707 18 199 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 1.3 0.696 – 2.43 0.411 11 169 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.982 0.918 – 1.05 0.597 1043 8142 exclusion phecode
742.1 Loose body in joint Musculoskeletal 1.18 0.825 – 1.69 0.363 28 422 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.894 0.715 – 1.12 0.325 85 933 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.25 0.957 – 1.63 0.102 62 634 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.973 0.908 – 1.04 0.446 985 8034 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.03 0.977 – 1.08 0.304 2537 8248 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.06 0.984 – 1.14 0.129 1230 3995 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.05 0.979 – 1.13 0.166 1217 3952 exclusion phecode
743.12 Senile osteoporosis Musculoskeletal 0.981 0.854 – 1.13 0.792 292 1134 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1.08 0.862 – 1.37 0.487 109 601 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.06 0.936 – 1.2 0.363 326 2028 exclusion phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 1.03 0.852 – 1.24 0.759 131 862 exclusion phecode
743.22 Pathologic fracture of femur Musculoskeletal 1.34 0.95 – 1.88 0.0956 43 267 exclusion phecode
743.4 Stress fracture Musculoskeletal 0.8 0.652 – 0.982 0.0325 120 924 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.02 0.96 – 1.07 0.595 1853 7744 exclusion phecode
745 Pain in joint Musculoskeletal 0.96 0.922 – 0.999 0.0427 4517 6498 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.985 0.897 – 1.08 0.743 525 4965 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.02 0.918 – 1.14 0.692 389 3920 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1.04 0.884 – 1.23 0.624 170 1512 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.17 0.965 – 1.41 0.111 128 1550 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.913 0.734 – 1.14 0.418 88 884 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.934 0.783 – 1.11 0.446 140 1163 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.977 0.657 – 1.45 0.909 29 272 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.91 0.78 – 1.06 0.228 206 1544 exclusion phecode
749.1 Cleft palate Congenital Anomalies 0.809 0.584 – 1.12 0.204 43 310 exclusion phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.939 0.674 – 1.31 0.71 46 303 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 1.14 0.996 – 1.3 0.0567 261 2050 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.999 0.799 – 1.25 0.992 88 858 exclusion phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.938 0.627 – 1.4 0.755 29 248 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.05 0.694 – 1.59 0.82 24 258 exclusion phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 0.996 0.723 – 1.37 0.979 39 269 exclusion phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 0.827 0.423 – 1.62 0.58 11 122 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.16 0.985 – 1.37 0.0749 176 1251 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.23 0.996 – 1.51 0.0543 110 720 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.07 0.814 – 1.42 0.615 69 509 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.04 0.941 – 1.14 0.473 518 4659 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.03 0.87 – 1.22 0.729 161 1548 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.2 0.979 – 1.47 0.0794 116 1100 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.77 0.558 – 1.06 0.113 38 353 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.01 0.894 – 1.13 0.914 332 3026 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 1.05 0.916 – 1.21 0.467 227 2060 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.936 0.73 – 1.2 0.603 74 675 exclusion phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.3 0.979 – 1.72 0.0693 62 532 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.14 0.988 – 1.31 0.0726 227 2647 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.18 1.01 – 1.38 0.0413 177 2072 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.969 0.714 – 1.32 0.84 42 500 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.03 0.782 – 1.35 0.838 58 599 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.04 0.771 – 1.41 0.779 52 476 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.664 0.362 – 1.22 0.185 14 150 exclusion phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 0.894 0.511 – 1.56 0.696 14 144 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.11 0.964 – 1.27 0.15 247 2582 exclusion phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 0.845 0.555 – 1.29 0.435 27 305 exclusion phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 1.1 0.897 – 1.34 0.365 109 1222 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.08 0.921 – 1.27 0.346 175 1999 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.04 0.828 – 1.3 0.743 78 912 exclusion phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 1.18 0.724 – 1.93 0.506 18 180 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.07 0.845 – 1.36 0.57 84 961 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.03 0.762 – 1.4 0.838 50 565 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.07 0.95 – 1.19 0.277 354 3352 exclusion phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.579 0.35 – 0.957 0.0332 21 172 exclusion phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 1.27 0.897 – 1.79 0.179 49 237 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.01 0.784 – 1.31 0.915 62 840 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.07 0.928 – 1.23 0.365 229 2290 exclusion phecode
757 Congenital anomalies of the integument Congenital Anomalies 0.829 0.666 – 1.03 0.0938 103 926 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.12 0.848 – 1.49 0.416 58 491 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.11 0.79 – 1.55 0.556 38 363 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.897 0.758 – 1.06 0.204 160 1493 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.857 0.51 – 1.44 0.561 14 188 exclusion phecode
760 Back pain Symptoms 1.09 1.05 – 1.14 6.76e-05 3440 7569 exclusion phecode
761 Cervicalgia Symptoms 1.05 0.994 – 1.11 0.083 1576 9228 exclusion phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 1.04 0.954 – 1.13 0.395 662 7263 exclusion phecode
764 Sciatica Symptoms 1.09 1 – 1.19 0.0411 611 7266 exclusion phecode
765 Cervical radiculitis Symptoms 1.06 0.952 – 1.19 0.277 371 3862 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.07 1 – 1.15 0.0484 1017 8661 exclusion phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.11 0.74 – 1.67 0.614 28 264 exclusion phecode
769 Nonallopathic lesions NEC Symptoms 1.07 0.941 – 1.22 0.302 292 2634 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.04 0.977 – 1.11 0.221 1254 8242 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.1 1.03 – 1.18 0.00721 1015 8355 exclusion phecode
771.1 Swelling of limb Symptoms 1.12 1.05 – 1.2 0.000866 1061 8316 exclusion phecode
771.2 Cramp of limb Symptoms 1.1 0.953 – 1.26 0.197 233 2375 exclusion phecode
772 Symptoms of the muscles Symptoms 0.949 0.863 – 1.04 0.28 507 4726 exclusion phecode
772.1 Muscular wasting and disuse atrophy Symptoms 1.06 0.875 – 1.29 0.536 123 1091 exclusion phecode
772.2 Spasm of muscle Symptoms 0.982 0.896 – 1.08 0.698 542 5508 exclusion phecode
772.3 Muscle weakness Symptoms 1.07 0.981 – 1.16 0.13 640 6137 exclusion phecode
772.4 Rhabdomyolysis Symptoms 1.34 0.943 – 1.91 0.102 38 338 exclusion phecode
772.6 Facial weakness Symptoms 0.905 0.727 – 1.13 0.37 96 1027 exclusion phecode
780 Hypothermia/Chills Symptoms 1.16 0.945 – 1.43 0.153 104 987 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.988 0.904 – 1.08 0.799 574 5709 exclusion phecode
781.1 Loss of height Symptoms 1.24 0.858 – 1.8 0.25 35 214 exclusion phecode
781.2 Abnormal posture Symptoms 0.979 0.534 – 1.8 0.946 14 123 exclusion phecode
782.3 Edema Symptoms 1.18 1.1 – 1.27 2.14e-06 976 8470 exclusion phecode
782.6 Pallor and flushing Symptoms 0.942 0.82 – 1.08 0.4 245 2410 exclusion phecode
783 Fever of unknown origin Symptoms 1.16 1.09 – 1.23 1.26e-06 1350 9562 exclusion phecode
783.1 Postprocedural fever Symptoms 1.18 0.889 – 1.56 0.254 58 642 exclusion phecode
785 Abdominal pain Symptoms 1.05 1.01 – 1.1 0.0113 3950 7061 exclusion phecode
788 Syncope and collapse Symptoms 1.04 0.971 – 1.12 0.246 887 8223 exclusion phecode
789 Nausea and vomiting Symptoms 1.1 1.05 – 1.15 2.94e-05 2685 8302 exclusion phecode
789.1 Persistent vomiting Symptoms 1.32 1.13 – 1.53 0.000375 203 1910 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.09 0.988 – 1.2 0.0862 499 4987 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.09 0.793 – 1.49 0.606 42 564 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.11 1.05 – 1.18 0.000362 1441 9098 exclusion phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 0.984 0.732 – 1.32 0.915 46 771 exclusion phecode
790.9 Abnormal arterial blood gases Symptoms 1.28 0.862 – 1.89 0.222 27 339 exclusion phecode
791 Gangrene Symptoms 1.22 0.961 – 1.55 0.103 77 589 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 1.04 0.967 – 1.13 0.273 885 4183 exclusion phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 1.07 0.957 – 1.2 0.229 370 2793 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.02 0.82 – 1.26 0.867 96 1118 exclusion phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 1.07 0.982 – 1.17 0.123 639 5303 exclusion phecode
795.8 Abnormal tumor markers Symptoms 0.941 0.831 – 1.07 0.339 295 2567 exclusion phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 1.05 0.577 – 1.91 0.874 11 129 exclusion phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 1.03 0.771 – 1.36 0.861 59 490 exclusion phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.802 0.703 – 0.915 0.00104 314 1514 exclusion phecode
797 Shock Symptoms 1.22 1 – 1.47 0.0461 129 1151 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.24 0.907 – 1.7 0.178 54 436 exclusion phecode
798 Malaise and fatigue Symptoms 1.07 1.02 – 1.12 0.00638 2655 8349 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1.05 0.938 – 1.17 0.41 383 4177 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.12 1.03 – 1.23 0.00964 595 5364 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.15 0.96 – 1.39 0.128 151 1086 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.1 0.936 – 1.28 0.253 192 1460 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.25 1.08 – 1.44 0.00216 221 2131 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.932 0.755 – 1.15 0.509 105 871 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.04 0.946 – 1.14 0.438 536 5414 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.1 0.958 – 1.25 0.184 249 2719 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.04 0.855 – 1.28 0.669 123 885 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 1.01 0.929 – 1.11 0.759 608 4860 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1.09 0.929 – 1.28 0.287 177 1770 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.993 0.886 – 1.11 0.906 360 2789 exclusion phecode
803.21 Colles' fracture Injuries & Poisonings 0.968 0.772 – 1.21 0.777 93 688 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.987 0.843 – 1.16 0.871 176 1228 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 1 0.911 – 1.11 0.921 491 3985 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.09 0.973 – 1.23 0.134 347 2856 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 0.987 0.843 – 1.16 0.876 177 1371 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.03 0.955 – 1.11 0.455 829 6736 exclusion phecode
816 Cerebral laceration and contusion Injuries & Poisonings 1.68 0.951 – 2.98 0.0741 16 101 exclusion phecode
817 Concussion Injuries & Poisonings 1.06 0.932 – 1.21 0.36 258 2679 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.19 0.945 – 1.5 0.139 85 688 exclusion phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 1.2 0.762 – 1.9 0.427 24 189 exclusion phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 1.04 0.648 – 1.68 0.857 24 203 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.1 1 – 1.19 0.0407 607 5516 exclusion phecode
830 Dislocation Injuries & Poisonings 0.912 0.848 – 0.982 0.0141 868 8371 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.915 0.829 – 1.01 0.0812 465 5322 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.897 0.708 – 1.14 0.369 80 1028 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.934 0.886 – 0.985 0.0122 1782 9030 exclusion phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.95 0.751 – 1.2 0.666 82 1115 exclusion phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.951 0.829 – 1.09 0.468 253 3256 exclusion phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.892 0.824 – 0.966 0.00507 746 6296 exclusion phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.939 0.834 – 1.06 0.292 339 3848 exclusion phecode
842 Other sprains and strains Injuries & Poisonings 1.02 0.911 – 1.15 0.684 334 3490 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.09 0.983 – 1.2 0.106 461 4470 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.26 1.16 – 1.36 6.34e-08 669 5863 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.34 1.09 – 1.65 0.00571 107 959 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.22 1.1 – 1.35 0.000253 412 4147 exclusion phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.12 0.832 – 1.5 0.459 54 619 exclusion phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.15 0.87 – 1.53 0.319 59 578 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.11 0.974 – 1.27 0.117 269 3092 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.16 1.05 – 1.27 0.00287 517 5130 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.19 1.08 – 1.3 0.000252 567 4779 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.38 0.95 – 1.99 0.0911 40 366 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.08 1.01 – 1.16 0.02 997 8403 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.26 0.94 – 1.68 0.123 55 444 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 0.816 0.58 – 1.15 0.241 41 324 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.01 0.902 – 1.12 0.904 392 3010 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.05 0.796 – 1.37 0.75 60 476 exclusion phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 1.21 0.96 – 1.52 0.106 93 604 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.947 0.734 – 1.22 0.678 64 395 exclusion phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.31 0.917 – 1.87 0.139 38 391 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.07 0.995 – 1.16 0.0666 808 7420 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.993 0.824 – 1.2 0.94 128 1282 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.917 0.798 – 1.05 0.218 233 2284 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.46 1.16 – 1.83 0.00108 85 951 exclusion phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.37 0.998 – 1.87 0.0513 44 583 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.19 0.975 – 1.46 0.0872 109 1075 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.5 1.05 – 2.13 0.0253 34 304 exclusion phecode
875 Non-healing surgical wound Injuries & Poisonings 1.09 0.905 – 1.32 0.357 127 1275 exclusion phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.07 0.901 – 1.27 0.447 148 1736 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.07 0.927 – 1.23 0.365 237 2291 exclusion phecode
910 Superficial injury, infected Injuries & Poisonings 0.863 0.552 – 1.35 0.52 22 268 exclusion phecode
911 Blister Injuries & Poisonings 1.07 0.793 – 1.44 0.659 50 571 exclusion phecode
912 Insect bite Injuries & Poisonings 1.02 0.834 – 1.25 0.837 112 1187 exclusion phecode
913 Toxic effect of venom Injuries & Poisonings 0.771 0.615 – 0.967 0.0244 85 744 exclusion phecode
916 Contusion Injuries & Poisonings 1.07 0.994 – 1.14 0.0722 987 8993 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.965 0.825 – 1.13 0.659 184 2047 exclusion phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.901 0.753 – 1.08 0.256 149 1629 exclusion phecode
938 Dermatitis due to solar radiation Dermatologic 0.9 0.845 – 0.958 0.00103 1328 6321 exclusion phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.93 0.686 – 1.26 0.642 48 508 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.89 0.834 – 0.949 0.00041 1269 6176 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.98 0.924 – 1.04 0.5 1492 7699 exclusion phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 1.11 0.74 – 1.66 0.621 28 224 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.899 0.631 – 1.28 0.557 37 380 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.4 1.08 – 1.83 0.0123 76 617 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.947 0.781 – 1.15 0.577 125 1147 exclusion phecode
947 Urticaria Dermatologic 1.03 0.905 – 1.16 0.687 287 2944 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.04 0.984 – 1.1 0.157 1617 7675 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.1 0.895 – 1.36 0.36 107 1049 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.735 0.52 – 1.04 0.0827 34 324 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.01 0.899 – 1.14 0.812 305 2721 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 0.849 0.597 – 1.21 0.363 38 329 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.29 0.89 – 1.87 0.179 34 249 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.2 1.09 – 1.32 0.000135 552 5167 exclusion phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 1.21 0.951 – 1.55 0.12 88 767 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.19 1.06 – 1.33 0.00422 342 3712 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.31 1.09 – 1.57 0.00395 138 1185 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.22 1.06 – 1.41 0.00566 233 2385 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.18 1.01 – 1.4 0.0424 172 1659 exclusion phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.17 0.923 – 1.48 0.197 84 794 exclusion phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 1.87 0.96 – 3.64 0.0656 11 118 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.12 0.909 – 1.39 0.284 99 974 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.16 1.07 – 1.26 0.000551 662 5444 exclusion phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.16 1.06 – 1.26 0.000827 644 5337 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.09 0.899 – 1.31 0.391 129 1472 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.09 0.897 – 1.33 0.381 120 1391 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.17 1.01 – 1.37 0.0399 199 2115 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.31 1.16 – 1.49 1.19e-05 303 3397 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.12 0.753 – 1.66 0.579 27 247 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.37 0.883 – 2.12 0.16 28 229 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.03 0.909 – 1.17 0.625 305 2905 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.48 1.14 – 1.92 0.00303 74 697 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.58 0.956 – 2.62 0.0741 18 124 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.29 0.962 – 1.74 0.089 51 576 exclusion phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 1.22 0.765 – 1.96 0.4 13 157 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.8 1.05 – 3.1 0.0322 16 198 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.75 1.08 – 2.83 0.0235 21 234 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.914 0.53 – 1.58 0.745 14 199 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.805 0.471 – 1.38 0.428 15 160 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.14 1.02 – 1.27 0.0236 383 3849 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.17 1.08 – 1.26 7.69e-05 797 7171 exclusion phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 1.02 0.899 – 1.15 0.77 288 2809 exclusion phecode
985 Toxic effect of other metals Injuries & Poisonings 1.65 0.88 – 3.09 0.119 17 92 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.26 0.884 – 1.79 0.203 34 302 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.15 1.07 – 1.23 0.000145 954 6503 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.25 1.13 – 1.38 2.13e-05 461 4485 exclusion phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.16 0.898 – 1.51 0.254 74 650 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.23 1.11 – 1.37 1e-04 429 4266 exclusion phecode
994.21 Septic shock Injuries & Poisonings 1.2 1 – 1.45 0.0495 138 1270 exclusion phecode
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