Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Body mass index Michigan Genomics Initiative Freeze 3 (MGI) PheWAS analysis

Body mass index — Michigan Genomics Initiative Freeze 3 (MGI) PRS PheWAS

PRS model
PRS ID exprsweb-bmi-23104-raw-pt-mgi-freeze3-20211120Legacy PTC+T (DS)UK Biobank GWAS

Evaluation cohort: Michigan Genomics Initiative Freeze 3 (MGI).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: normal-range subset (18.5-24.9).

For this ExPRS, the exclusion sensitivity scan keeps only the study's normal-range subset for Body mass index (18.5-24.9) before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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716 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.02 0.98 – 1.06 0.335 3004 29292 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.11 1.04 – 1.17 0.00106 1322 13162 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.1 1.03 – 1.18 0.00411 1046 10455 all phecode
008.6 Viral Enteritis Infectious Diseases 1.09 1.01 – 1.18 0.0236 770 7676 all phecode
010 Tuberculosis Infectious Diseases 1.09 0.952 – 1.26 0.207 244 2425 all phecode
031 Diseases due to other mycobacteria Infectious Diseases 0.976 0.776 – 1.23 0.837 86 855 all phecode
038 Septicemia Infectious Diseases 1.13 1.08 – 1.18 1.71e-08 2582 24779 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.13 1.03 – 1.23 0.0117 568 5629 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.22 1.06 – 1.4 0.00664 235 2350 all phecode
038.3 Bacteremia Infectious Diseases 1.15 1.08 – 1.23 6.65e-06 1210 12079 all phecode
041 Bacterial infection NOS Infectious Diseases 1.09 1.06 – 1.12 1.84e-08 5750 38799 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.18 1.12 – 1.24 1.46e-09 1707 16977 all phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.22 1.14 – 1.31 3.86e-08 920 9192 all phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.2 1.11 – 1.3 2.63e-06 783 7812 all phecode
041.2 Streptococcus infection Infectious Diseases 1.11 1.05 – 1.17 9.59e-05 1632 16287 all phecode
041.21 Rheumatic fever / chorea Infectious Diseases 1.02 0.886 – 1.16 0.83 257 2554 all phecode
041.4 E. coli Infectious Diseases 1.09 1.03 – 1.17 0.00547 1175 11680 all phecode
041.8 H. pylori Infectious Diseases 1.05 0.917 – 1.2 0.478 257 2521 all phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.18 1.06 – 1.32 0.00315 387 3864 all phecode
053 Herpes zoster Infectious Diseases 0.938 0.888 – 0.991 0.0236 1560 15184 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.885 0.764 – 1.02 0.103 220 2169 all phecode
054 Herpes simplex Infectious Diseases 0.936 0.886 – 0.989 0.0178 1593 15600 all phecode
070 Viral hepatitis Infectious Diseases 1.07 0.989 – 1.15 0.0926 829 8280 all phecode
070.1 Viral hepatitis A Infectious Diseases 1.09 0.865 – 1.38 0.46 87 860 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.1 0.951 – 1.28 0.193 215 2138 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.07 0.975 – 1.18 0.149 528 5280 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.12 0.956 – 1.31 0.159 197 1964 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.01 0.948 – 1.08 0.738 1145 11381 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.12 0.948 – 1.33 0.18 145 1450 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.11 0.913 – 1.34 0.304 117 1163 all phecode
078 Viral warts & HPV Infectious Diseases 0.915 0.881 – 0.95 3.03e-06 3434 29624 all phecode
079 Viral infection Infectious Diseases 0.953 0.927 – 0.98 0.000717 6664 35342 all phecode
079.1 Varicella infection Infectious Diseases 0.901 0.869 – 0.934 1.28e-08 3793 31251 all phecode
079.2 Infectious mononucleosis Infectious Diseases 0.874 0.769 – 0.993 0.0393 283 2723 all phecode
079.9 Viremia, NOS Infectious Diseases 1.06 0.98 – 1.14 0.151 838 8253 all phecode
080 Postoperative infection Infectious Diseases 1.14 1.1 – 1.19 6.27e-10 2619 26065 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.13 1.07 – 1.19 1.18e-05 1589 15884 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.02 0.956 – 1.1 0.494 965 9630 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.02 0.986 – 1.06 0.222 3544 30054 all phecode
110.1 Dermatophytosis Infectious Diseases 1.03 0.994 – 1.07 0.0979 3241 27244 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.05 1 – 1.11 0.039 2044 16765 all phecode
110.12 Althete's foot Infectious Diseases 1.08 1 – 1.16 0.0369 899 8043 all phecode
110.13 Dermatophytosis of the body Infectious Diseases 1.05 0.969 – 1.13 0.247 790 7827 all phecode
110.2 Dermatomycoses Infectious Diseases 0.954 0.857 – 1.06 0.393 398 3971 all phecode
112 Candidiasis Infectious Diseases 1.11 1.07 – 1.15 1.2e-08 3685 30495 all phecode
112.3 Candidiasis of skin and nails Infectious Diseases 1.31 1.2 – 1.42 4.92e-10 682 6732 all phecode
117 Mycoses Infectious Diseases 1.01 0.924 – 1.1 0.857 608 6069 all phecode
117.1 Histoplasmosis Infectious Diseases 1.13 0.892 – 1.43 0.308 81 801 all phecode
117.4 Aspergillosis Infectious Diseases 1.03 0.862 – 1.23 0.759 140 1387 all phecode
130 Spirochetal infection Infectious Diseases 0.911 0.774 – 1.07 0.26 168 1677 all phecode
130.1 Lyme disease Infectious Diseases 0.909 0.747 – 1.11 0.341 116 1160 all phecode
131 Protozoan infection Infectious Diseases 1.41 1.09 – 1.82 0.00972 61 610 all phecode
132 Infestation (lice, mites) Infectious Diseases 1.1 0.943 – 1.28 0.229 195 1948 all phecode
134 Helminthiases Infectious Diseases 0.993 0.788 – 1.25 0.953 83 812 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.1 0.818 – 1.48 0.53 53 513 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.05 1.01 – 1.09 0.00839 3279 32486 all phecode
145 Cancer of mouth Neoplasms 1.03 0.973 – 1.09 0.323 1481 14725 all phecode
145.1 Cancer of lip Neoplasms 1.08 0.845 – 1.37 0.55 76 750 all phecode
145.2 Cancer of tongue Neoplasms 1.01 0.929 – 1.1 0.79 645 6430 all phecode
145.3 Cancer of major salivary glands Neoplasms 0.986 0.88 – 1.1 0.802 361 3597 all phecode
145.4 Cancer of the gums Neoplasms 1.04 0.875 – 1.23 0.661 166 1632 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.07 0.921 – 1.24 0.384 206 2048 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.03 0.965 – 1.09 0.418 1290 12873 all phecode
149.1 Cancer of oropharynx Neoplasms 1.02 0.911 – 1.15 0.714 350 3499 all phecode
149.2 Cancer of nasopharynx Neoplasms 1.09 0.876 – 1.35 0.45 100 1000 all phecode
149.3 Cancer of hypopharynx Neoplasms 1.02 0.798 – 1.31 0.861 82 819 all phecode
149.4 Cancer of larynx Neoplasms 1.18 1.05 – 1.31 0.00397 386 3857 all phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 1.01 0.923 – 1.11 0.809 552 5505 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.909 0.79 – 1.05 0.182 240 2398 all phecode
150 Cancer of esophagus Neoplasms 1.25 1.13 – 1.39 1.91e-05 433 4315 all phecode
151 Cancer of stomach Neoplasms 1.11 1 – 1.22 0.043 498 4962 all phecode
153 Colorectal cancer Neoplasms 0.981 0.927 – 1.04 0.523 1458 14383 all phecode
153.2 Colon cancer Neoplasms 0.989 0.928 – 1.06 0.746 1160 11472 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.959 0.888 – 1.04 0.289 815 8093 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.07 0.977 – 1.18 0.141 511 5097 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.12 0.995 – 1.25 0.0598 344 3433 all phecode
157 Pancreatic cancer Neoplasms 1.04 0.94 – 1.14 0.485 503 5005 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.02 0.971 – 1.08 0.379 1623 15759 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.04 0.99 – 1.1 0.111 1818 17869 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.06 0.916 – 1.23 0.425 221 2206 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.01 0.854 – 1.2 0.887 158 1578 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.02 0.893 – 1.16 0.81 293 2920 all phecode
164 Cancer of intrathoracic organs Neoplasms 0.938 0.779 – 1.13 0.495 133 1324 all phecode
165 Cancer within the respiratory system Neoplasms 1.06 1 – 1.13 0.0514 1336 13340 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.05 0.984 – 1.13 0.135 1057 10552 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.975 0.926 – 1.03 0.33 1792 17850 all phecode
170.1 Bone cancer Neoplasms 0.963 0.891 – 1.04 0.338 773 7690 all phecode
170.2 Cancer of connective tissue Neoplasms 0.966 0.909 – 1.03 0.264 1266 12632 all phecode
172 Skin cancer Neoplasms 0.944 0.919 – 0.969 1.41e-05 8608 33186 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.924 0.895 – 0.953 8.49e-07 5330 30106 all phecode
172.11 Melanomas of skin Neoplasms 0.925 0.889 – 0.962 0.000109 3100 25064 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.94 0.914 – 0.967 2.23e-05 7095 30462 all phecode
172.21 Basal cell carcinoma Neoplasms 0.904 0.871 – 0.939 1.43e-07 3690 23868 all phecode
172.22 Squamous cell carcinoma Neoplasms 0.975 0.931 – 1.02 0.267 2414 17683 all phecode
172.3 Carcinoma in situ of skin Neoplasms 0.881 0.831 – 0.933 1.43e-05 1482 12326 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.911 0.867 – 0.957 0.000185 1997 18755 all phecode
174 Breast cancer Neoplasms 0.916 0.879 – 0.955 3.39e-05 3186 15514 all phecode
174.1 Breast cancer [female] Neoplasms 0.914 0.876 – 0.954 3.59e-05 3036 14701 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.917 0.878 – 0.957 6.79e-05 2991 14639 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.828 0.717 – 0.957 0.0103 233 2307 all phecode
175 Acquired absence of breast Neoplasms 0.953 0.885 – 1.03 0.196 919 8920 all phecode
180 Cervical cancer and dysplasia Neoplasms 1.02 0.965 – 1.08 0.448 1431 12185 all phecode
180.1 Cervical cancer Neoplasms 1.09 0.992 – 1.21 0.0734 500 4982 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.981 0.917 – 1.05 0.57 1048 9323 all phecode
182 Malignant neoplasm of uterus Neoplasms 1.15 1.06 – 1.25 0.000579 765 7613 all phecode
184 Cancer of other female genital organs Neoplasms 1.01 0.95 – 1.08 0.693 1191 11592 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.982 0.895 – 1.08 0.7 573 5719 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.954 0.858 – 1.06 0.381 432 4309 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.06 0.971 – 1.16 0.191 608 6057 all phecode
185 Cancer of prostate Neoplasms 0.948 0.906 – 0.992 0.021 2901 10342 all phecode
187 Cancer of other male genital organs Neoplasms 0.951 0.846 – 1.07 0.404 339 3384 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.1 0.893 – 1.34 0.381 115 1141 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.935 0.798 – 1.09 0.399 183 1830 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.828 0.617 – 1.11 0.206 57 562 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.11 1.06 – 1.15 7.98e-07 2923 23541 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.12 1.06 – 1.19 6.95e-05 1450 14437 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.14 1.07 – 1.21 3.85e-05 1267 12655 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.08 0.94 – 1.25 0.267 237 2347 all phecode
189.2 Cancer of bladder Neoplasms 1.09 1.04 – 1.15 0.000669 1783 15224 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.09 1.04 – 1.15 0.00127 1657 14178 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.07 0.985 – 1.16 0.107 678 6586 all phecode
190 Cancer of eye Neoplasms 0.839 0.699 – 1.01 0.0603 138 1374 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.985 0.923 – 1.05 0.651 1078 10771 all phecode
191.1 Cancer of brain and nervous system Neoplasms 0.958 0.885 – 1.04 0.298 706 7052 all phecode
191.11 Cancer of brain Neoplasms 0.945 0.866 – 1.03 0.201 600 5996 all phecode
193 Thyroid cancer Neoplasms 1.01 0.943 – 1.09 0.745 945 9393 all phecode
194 Cancer of other endocrine glands Neoplasms 1.02 0.933 – 1.12 0.654 579 5759 all phecode
195 Cancer, suspected or other Neoplasms 1.01 0.985 – 1.03 0.552 16962 26401 all phecode
195.1 Malignant neoplasm, other Neoplasms 1 0.982 – 1.03 0.769 16670 26384 all phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1.03 0.966 – 1.1 0.363 1103 9766 all phecode
196 Radiotherapy Neoplasms 0.923 0.882 – 0.966 0.000517 2427 17006 all phecode
197 Chemotherapy Neoplasms 1 0.97 – 1.04 0.891 4952 23797 all phecode
198 Secondary malignant neoplasm Neoplasms 1.02 0.987 – 1.05 0.248 5801 23481 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.998 0.961 – 1.04 0.907 3677 21489 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.07 1 – 1.14 0.051 1072 10334 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.03 0.959 – 1.11 0.396 866 8538 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.02 0.94 – 1.1 0.668 767 7558 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.02 0.935 – 1.11 0.677 640 6338 all phecode
198.6 Secondary malignancy of bone Neoplasms 1 0.933 – 1.08 0.9 866 8307 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.943 0.837 – 1.06 0.327 336 3253 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.01 0.981 – 1.04 0.45 5693 25767 all phecode
199.4 Neurofibromatosis Neoplasms 1 0.806 – 1.25 0.965 88 880 all phecode
200 Myeloproliferative disease Neoplasms 1.06 0.991 – 1.13 0.0927 1113 11098 all phecode
200.1 Polycythemia vera Neoplasms 1.13 0.983 – 1.31 0.085 231 2310 all phecode
201 Hodgkin's disease Neoplasms 1.16 0.985 – 1.36 0.0756 172 1705 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.03 0.977 – 1.09 0.253 1559 15571 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.02 0.961 – 1.08 0.518 1329 13268 all phecode
202.21 Nodular lymphoma Neoplasms 0.975 0.898 – 1.06 0.549 693 6923 all phecode
202.22 Reticulosarcoma Neoplasms 1.17 0.995 – 1.39 0.0573 170 1693 all phecode
202.24 Large cell lymphoma Neoplasms 1.05 0.884 – 1.24 0.586 160 1586 all phecode
204 Leukemia Neoplasms 1.04 0.958 – 1.13 0.339 689 6876 all phecode
204.1 Lymphoid leukemia Neoplasms 0.885 0.769 – 1.02 0.0869 236 2354 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.922 0.727 – 1.17 0.504 74 734 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.844 0.714 – 0.999 0.0483 173 1724 all phecode
204.2 Myeloid leukemia Neoplasms 1.14 1 – 1.31 0.0496 265 2633 all phecode
204.21 Myeloid leukemia, acute Neoplasms 1.22 1.03 – 1.46 0.0235 153 1516 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.19 0.885 – 1.59 0.253 61 610 all phecode
204.4 Multiple myeloma Neoplasms 1.14 0.984 – 1.32 0.0819 217 2162 all phecode
208 Benign neoplasm of colon Neoplasms 0.99 0.967 – 1.01 0.393 10303 34953 all phecode
209 Neuroendocrine tumors Neoplasms 1.06 0.923 – 1.21 0.415 258 2580 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.992 0.944 – 1.04 0.766 1891 18839 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.09 1.06 – 1.12 3.41e-10 7329 36606 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.06 1.01 – 1.11 0.0254 1843 18412 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.992 0.941 – 1.05 0.765 1677 15527 all phecode
214 Lipoma Neoplasms 0.983 0.928 – 1.04 0.568 1437 14132 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.959 0.89 – 1.03 0.264 883 8710 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1 0.972 – 1.04 0.815 4528 39509 all phecode
216 Benign neoplasm of skin Neoplasms 0.929 0.909 – 0.95 1.59e-10 11528 34919 all phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 0.902 0.763 – 1.07 0.225 174 1701 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.838 0.795 – 0.882 2.34e-11 1786 17184 all phecode
217.1 Nevus, non-neoplastic Neoplasms 0.84 0.796 – 0.886 1.75e-10 1679 16116 all phecode
218 Benign neoplasm of uterus Neoplasms 0.985 0.95 – 1.02 0.393 4301 16661 all phecode
218.1 Uterine leiomyoma Neoplasms 0.944 0.896 – 0.995 0.0302 1835 15733 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.992 0.954 – 1.03 0.694 3403 16447 all phecode
220 Benign neoplasm of ovary Neoplasms 1.04 0.966 – 1.12 0.307 893 8783 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.01 0.966 – 1.07 0.557 2042 14248 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.9 0.844 – 0.959 0.00122 1133 10663 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.07 1.01 – 1.12 0.0169 1801 12657 all phecode
224 Benign neoplasm of eye Neoplasms 0.962 0.884 – 1.05 0.359 691 6752 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.946 0.865 – 1.03 0.224 595 5773 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.03 0.965 – 1.09 0.402 1209 12074 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.02 0.947 – 1.09 0.661 947 9454 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.03 0.908 – 1.17 0.632 289 2890 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.02 0.963 – 1.09 0.472 1329 13264 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.02 0.967 – 1.08 0.465 1690 16896 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.15 1.04 – 1.27 0.00805 467 4644 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.942 0.871 – 1.02 0.127 795 7941 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.04 0.934 – 1.15 0.508 435 4350 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.866 0.826 – 0.908 2.82e-09 2149 20946 all phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.844 0.795 – 0.896 2.67e-08 1356 13336 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.995 0.969 – 1.02 0.705 7767 36615 all phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.983 0.954 – 1.01 0.255 5743 34218 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.04 0.973 – 1.11 0.246 1031 9761 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.05 1 – 1.09 0.0301 2910 22227 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.04 0.994 – 1.09 0.0913 2265 19902 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.07 1.01 – 1.14 0.0194 1304 12479 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.05 0.994 – 1.12 0.0775 1400 13425 all phecode
242.1 Graves' disease Endocrine/metabolic 1.07 0.968 – 1.17 0.194 515 5068 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.16 0.952 – 1.41 0.14 124 1224 all phecode
242.3 Exophthalmos Endocrine/metabolic 0.993 0.876 – 1.13 0.914 292 2898 all phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 1.04 0.87 – 1.25 0.643 144 1432 all phecode
244 Hypothyroidism Endocrine/metabolic 1.06 1.04 – 1.09 5.37e-06 8099 32717 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1 0.95 – 1.05 0.993 1762 17230 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.05 0.99 – 1.12 0.0996 1261 11982 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.07 1.04 – 1.1 3.72e-06 7542 32208 all phecode
245 Thyroiditis Endocrine/metabolic 1.13 1.04 – 1.21 0.00236 832 7882 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.14 1.05 – 1.24 0.00218 686 6517 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.13 1.04 – 1.23 0.0043 679 6449 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.04 1.01 – 1.07 0.0117 6129 30240 all phecode
246.2 Thyroid cyst Endocrine/metabolic 0.844 0.685 – 1.04 0.113 101 960 all phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1.02 0.949 – 1.1 0.589 886 8696 all phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.34 1.25 – 1.44 4.27e-15 1150 8340 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.26 1.23 – 1.29 1.06e-87 13947 31815 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.29 1.21 – 1.37 4.19e-16 2364 11758 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.14 0.95 – 1.36 0.162 262 960 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.19 1.06 – 1.34 0.00408 551 2686 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.3 1.16 – 1.46 5.04e-06 784 3018 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.27 1.13 – 1.44 7.92e-05 638 2675 all phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 1.14 0.931 – 1.39 0.206 155 850 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.37 1.33 – 1.41 2.19e-115 9843 29688 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.3 1.11 – 1.52 0.00102 282 1327 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.51 1.43 – 1.6 1.97e-43 1941 13510 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.44 1.34 – 1.54 4.07e-25 1643 9668 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.53 1.45 – 1.61 1.7e-56 2557 16502 all phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.49 1.37 – 1.63 1.25e-19 860 6143 all phecode
250.3 Insulin pump user Endocrine/metabolic 1.44 1.37 – 1.5 2.02e-53 3496 20809 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.16 1.13 – 1.19 3.32e-25 8385 30645 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.12 1.06 – 1.18 4.4e-05 1870 15861 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.17 1.13 – 1.2 1.38e-24 7553 30071 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.14 0.939 – 1.39 0.185 136 1067 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.54 1.45 – 1.64 8.25e-47 2132 13390 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.23 1.16 – 1.3 7.73e-12 1691 10517 all phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.08 1.01 – 1.16 0.0319 991 8469 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.19 1.11 – 1.28 2.96e-06 1207 8570 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.07 1.02 – 1.12 0.00297 2282 22119 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.07 1.02 – 1.12 0.00679 2088 20335 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.02 0.926 – 1.12 0.694 508 5073 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.02 0.945 – 1.09 0.656 859 8544 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.09 0.956 – 1.24 0.197 263 2621 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.16 0.915 – 1.47 0.219 83 826 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.01 0.877 – 1.16 0.905 226 2250 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.07 0.85 – 1.35 0.566 86 860 all phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 1.04 0.855 – 1.26 0.717 121 1209 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.961 0.784 – 1.18 0.703 108 1080 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.14 1.07 – 1.2 9.39e-06 1506 14869 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.03 0.92 – 1.15 0.635 373 3730 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.05 0.899 – 1.23 0.526 183 1830 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.04 0.866 – 1.25 0.67 135 1350 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.05 0.963 – 1.15 0.268 626 6239 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.06 0.966 – 1.15 0.229 596 5941 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.16 1.09 – 1.24 6.24e-06 1146 10513 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.32 1.22 – 1.43 1.41e-11 742 7128 all phecode
257 Testicular dysfunction Endocrine/metabolic 1.02 0.957 – 1.1 0.492 1015 9238 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.02 0.952 – 1.09 0.575 983 8933 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.3 1.04 – 1.63 0.0212 91 910 all phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.992 0.806 – 1.22 0.942 109 1090 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.09 1.02 – 1.17 0.00945 1038 10259 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.05 1.01 – 1.1 0.0141 2880 26812 all phecode
260.1 Cachexia Endocrine/metabolic 1 0.881 – 1.13 0.995 292 2911 all phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.08 1.02 – 1.13 0.00603 1691 16847 all phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.07 0.978 – 1.17 0.142 614 6140 all phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.06 0.977 – 1.16 0.155 629 6236 all phecode
260.6 Anorexia Endocrine/metabolic 1.03 0.957 – 1.11 0.42 868 8591 all phecode
260.7 Polyphagia Endocrine/metabolic 1.14 0.877 – 1.49 0.322 65 643 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.13 1.1 – 1.16 1.06e-18 7718 35203 all phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1.13 0.871 – 1.48 0.349 69 690 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.22 1.14 – 1.32 1.29e-07 857 8405 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.13 1.1 – 1.16 5.37e-18 7255 35225 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.839 0.632 – 1.11 0.223 52 511 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.2 1.13 – 1.28 2.05e-08 1182 11676 all phecode
263 Other nutritional deficiency Endocrine/metabolic 1.09 1.03 – 1.15 0.00219 1651 15788 all phecode
264 Lack of normal physiological development Endocrine/metabolic 0.964 0.839 – 1.11 0.604 239 2301 all phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 0.967 0.797 – 1.17 0.731 122 1220 all phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 0.943 0.747 – 1.19 0.621 81 772 all phecode
269 Proteinuria Endocrine/metabolic 1.18 1.12 – 1.24 2.45e-09 1694 13981 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.04 0.974 – 1.12 0.228 967 9575 all phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.939 0.795 – 1.11 0.457 170 1697 all phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.958 0.796 – 1.15 0.646 134 1334 all phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 1.11 0.893 – 1.37 0.356 96 954 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.05 0.968 – 1.13 0.251 737 7303 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.1 0.987 – 1.24 0.0836 384 3781 all phecode
270.33 Amyloidosis Endocrine/metabolic 0.987 0.764 – 1.27 0.917 71 695 all phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 0.771 0.588 – 1.01 0.0607 69 690 all phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.07 0.944 – 1.21 0.299 299 2984 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.02 0.976 – 1.06 0.42 2907 28132 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.02 0.976 – 1.06 0.421 2827 27425 all phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.977 0.792 – 1.21 0.829 102 1007 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.1 1.08 – 1.12 1.08e-17 18881 26670 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.1 1.08 – 1.12 1.14e-17 18843 26654 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.06 1.03 – 1.1 0.000232 5928 21600 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.13 1.07 – 1.2 3.57e-05 1360 11837 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.12 1.07 – 1.16 1.43e-07 3538 18449 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.03 0.912 – 1.16 0.625 313 3011 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.19 1.14 – 1.24 5.99e-15 2524 22729 all phecode
274.1 Gout Endocrine/metabolic 1.2 1.15 – 1.26 8e-16 2409 21991 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.19 1.11 – 1.27 3.51e-07 1082 10576 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.01 0.864 – 1.19 0.872 195 1890 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.995 0.845 – 1.17 0.95 183 1772 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.08 1.04 – 1.11 1.03e-05 4357 37091 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.915 0.791 – 1.06 0.23 218 2180 all phecode
275.11 Hereditary hemochromatosis Hematopoietic 0.882 0.712 – 1.09 0.249 99 990 all phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 1.06 0.811 – 1.4 0.656 62 614 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.16 1.09 – 1.24 3.3e-06 1154 11504 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.07 1.03 – 1.11 0.000394 3369 31544 all phecode
275.51 Hypocalcemia Endocrine/metabolic 1.03 0.959 – 1.11 0.406 898 8969 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.09 1.03 – 1.15 0.00472 1366 13634 all phecode
275.6 Hypercalcemia Endocrine/metabolic 1.07 1.01 – 1.13 0.0293 1468 14183 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.12 1.09 – 1.15 3.3e-19 9238 37046 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.12 1.09 – 1.16 2.16e-15 6352 34366 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.17 1.07 – 1.29 0.000828 550 5434 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.1 1.05 – 1.15 2.01e-05 2514 23219 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.17 1.13 – 1.22 1.01e-14 2992 25216 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.1 1.05 – 1.15 7.3e-05 2148 20909 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.14 1.09 – 1.2 4.53e-08 2086 20332 all phecode
276.41 Acidosis Endocrine/metabolic 1.14 1.08 – 1.2 8.94e-07 1788 17572 all phecode
276.42 Alkalosis Endocrine/metabolic 1.15 1.04 – 1.27 0.00529 476 4741 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.11 1.08 – 1.15 8.78e-11 4574 34527 all phecode
276.6 Fluid overload Endocrine/metabolic 1.27 1.19 – 1.34 4.93e-15 1384 13211 all phecode
276.8 Polydipsia Endocrine/metabolic 0.807 0.667 – 0.978 0.0287 124 1240 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.13 1.09 – 1.16 1.86e-11 4112 35070 all phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.4 1.26 – 1.56 7.08e-10 403 3991 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.965 0.891 – 1.05 0.388 720 7161 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.05 0.983 – 1.13 0.139 936 9270 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.11 1.02 – 1.2 0.0102 773 7668 all phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 1.35 1.25 – 1.45 2.69e-15 916 8359 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.57 1.54 – 1.61 6.48e-399 19419 27331 all phecode
278.1 Obesity Endocrine/metabolic 1.67 1.63 – 1.7 1.4e-457 17129 27321 all phecode
278.11 Morbid obesity Endocrine/metabolic 1.96 1.9 – 2.01 1.24e-454 8280 27172 all phecode
278.3 Localized adiposity Endocrine/metabolic 1.78 1.57 – 2.02 7.93e-20 324 3228 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.4 1.33 – 1.47 3.81e-40 2104 17411 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.03 0.992 – 1.07 0.12 2934 28612 all phecode
279.1 Immunity deficiency Endocrine/metabolic 0.995 0.934 – 1.06 0.87 1161 11571 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.977 0.868 – 1.1 0.702 330 3278 all phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 1.01 0.931 – 1.09 0.821 754 7516 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.01 0.978 – 1.04 0.546 4885 36552 all phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 0.988 0.904 – 1.08 0.797 601 5988 all phecode
280 Iron deficiency anemias Hematopoietic 1.12 1.08 – 1.15 8.71e-11 4626 30873 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.11 1.08 – 1.15 2.86e-10 4484 30649 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.09 1.04 – 1.15 0.00063 1771 17196 all phecode
281 Other deficiency anemia Hematopoietic 1.04 0.944 – 1.14 0.436 519 5120 all phecode
281.1 Megaloblastic anemia Hematopoietic 1.01 0.876 – 1.16 0.928 253 2497 all phecode
281.11 Pernicious anemia Hematopoietic 1.1 0.896 – 1.35 0.363 114 1108 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.99 0.845 – 1.16 0.902 187 1817 all phecode
281.9 Deficiency anemias Hematopoietic 1.04 0.912 – 1.18 0.572 285 2830 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.08 0.956 – 1.23 0.211 323 3188 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.07 0.918 – 1.24 0.39 216 2113 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.16 0.991 – 1.36 0.0644 192 1920 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.14 0.959 – 1.37 0.136 155 1550 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.27 0.954 – 1.68 0.103 64 633 all phecode
284 Aplastic anemia Hematopoietic 1.06 0.977 – 1.15 0.16 697 6943 all phecode
284.1 Pancytopenia Hematopoietic 1.07 0.98 – 1.17 0.13 612 6100 all phecode
285 Other anemias Hematopoietic 1.09 1.07 – 1.12 3.53e-14 11794 33591 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.09 1.05 – 1.14 3.48e-06 3325 27709 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.13 1.07 – 1.18 1.37e-06 2055 19939 all phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.22 1.13 – 1.31 5.2e-08 932 9106 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.04 0.953 – 1.13 0.41 690 6892 all phecode
286 Coagulation defects Hematopoietic 1.09 1.06 – 1.13 6.5e-07 3844 33384 all phecode
286.1 Congenital coagulation defects Hematopoietic 1.04 0.906 – 1.19 0.585 250 2466 all phecode
286.11 Von willebrand's disease Hematopoietic 1.15 0.917 – 1.44 0.226 83 822 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.996 0.824 – 1.2 0.969 126 1260 all phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.12 1.08 – 1.16 7.34e-09 3354 25918 all phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 0.891 0.708 – 1.12 0.328 97 962 all phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 1.13 0.985 – 1.29 0.0826 254 2529 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.15 0.963 – 1.38 0.122 132 1294 all phecode
286.6 Defibrination syndrome Hematopoietic 1.1 1.05 – 1.14 2.91e-05 2579 25377 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.09 1.05 – 1.13 3.21e-05 3014 29294 all phecode
286.8 Hypercoagulable state Hematopoietic 1.13 1.05 – 1.21 0.00181 846 8437 all phecode
286.81 Primary hypercoagulable state Hematopoietic 1.12 1.04 – 1.21 0.00312 813 8111 all phecode
286.9 Abnormal coagulation profile Hematopoietic 1.14 1.07 – 1.21 5.17e-05 1182 11487 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.07 1.03 – 1.12 0.000217 3288 28474 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.02 0.877 – 1.18 0.835 211 2094 all phecode
287.3 Thrombocytopenia Hematopoietic 1.07 1.02 – 1.11 0.00188 2938 26323 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.08 0.992 – 1.18 0.073 601 5994 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.01 0.926 – 1.11 0.768 569 5686 all phecode
287.4 Qualitative platelet defects Hematopoietic 1.26 1.03 – 1.55 0.0254 112 1120 all phecode
288 Diseases of white blood cells Hematopoietic 1.07 1.03 – 1.1 5.29e-05 4886 36527 all phecode
288.1 Decreased white blood cell count Hematopoietic 0.99 0.938 – 1.05 0.727 1599 15951 all phecode
288.11 Neutropenia Hematopoietic 0.994 0.931 – 1.06 0.845 1106 11041 all phecode
288.2 Elevated white blood cell count Hematopoietic 1.09 1.05 – 1.12 2.78e-06 4082 35079 all phecode
288.3 Eosinophilia Hematopoietic 0.855 0.729 – 1 0.0552 187 1866 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.03 0.979 – 1.09 0.245 1757 17434 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.01 0.938 – 1.08 0.821 918 9087 all phecode
289.4 Lymphadenitis Hematopoietic 1.07 1.03 – 1.11 0.000224 3888 34715 all phecode
289.5 Diseases of spleen Hematopoietic 1.04 0.937 – 1.16 0.432 393 3913 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.08 0.943 – 1.23 0.268 255 2550 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.09 0.976 – 1.22 0.128 385 3813 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.02 0.96 – 1.08 0.514 1318 11547 all phecode
290.1 Dementias Mental Disorders 0.989 0.9 – 1.09 0.826 541 4910 all phecode
290.11 Alzheimer's disease Mental Disorders 0.976 0.812 – 1.17 0.793 151 1389 all phecode
290.12 Dementia with cerebral degenerations Mental Disorders 1 0.793 – 1.26 0.995 88 846 all phecode
290.13 Senile dementia Mental Disorders 0.962 0.853 – 1.08 0.526 340 3078 all phecode
290.16 Vascular dementia Mental Disorders 0.845 0.665 – 1.07 0.169 81 777 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.04 0.96 – 1.13 0.333 750 7358 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.928 0.863 – 0.998 0.0434 886 8618 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.02 0.976 – 1.06 0.388 2550 24810 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.978 0.831 – 1.15 0.785 175 1750 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.964 0.875 – 1.06 0.458 484 4807 all phecode
291.8 Alteration of consciousness Mental Disorders 1.04 0.987 – 1.09 0.149 2036 19974 all phecode
292 Neurological disorders Mental Disorders 1.02 0.993 – 1.05 0.132 5733 38553 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.993 0.947 – 1.04 0.788 2013 19867 all phecode
292.11 Aphasia Mental Disorders 0.976 0.898 – 1.06 0.577 664 6581 all phecode
292.12 Symbolic dysfunction Mental Disorders 1.01 0.867 – 1.17 0.908 200 1988 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.946 0.847 – 1.06 0.326 389 3731 all phecode
292.3 Memory loss Mental Disorders 0.96 0.914 – 1.01 0.109 1922 18158 all phecode
292.4 Altered mental status Mental Disorders 1.07 1.03 – 1.12 0.00129 2454 22725 all phecode
292.5 Transient alteration of awareness Mental Disorders 1.01 0.909 – 1.11 0.915 430 4285 all phecode
292.6 Hallucinations Mental Disorders 1.09 0.941 – 1.26 0.248 217 2147 all phecode
293 Symptoms involving head and neck Mental Disorders 0.907 0.816 – 1.01 0.0718 414 4127 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.03 1 – 1.07 0.0523 4417 38609 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.07 0.997 – 1.15 0.0611 885 8229 all phecode
295.1 Schizophrenia Mental Disorders 1.01 0.842 – 1.21 0.914 138 1339 all phecode
295.2 Paranoid disorders Mental Disorders 1.09 0.894 – 1.34 0.385 118 1079 all phecode
295.3 Psychosis Mental Disorders 1.09 1 – 1.18 0.0423 716 6694 all phecode
296 Mood disorders Mental Disorders 1.09 1.06 – 1.11 7.16e-13 15356 20858 all phecode
296.1 Bipolar Mental Disorders 1.17 1.1 – 1.24 4.81e-07 1301 11264 all phecode
296.2 Depression Mental Disorders 1.09 1.06 – 1.11 1.33e-12 14833 20856 all phecode
296.22 Major depressive disorder Mental Disorders 1.09 1.06 – 1.11 9.76e-13 13850 20853 all phecode
297 Suicidal ideation or attempt Mental Disorders 1.09 1.02 – 1.17 0.0154 985 9050 all phecode
297.1 Suicidal ideation Mental Disorders 1.08 1 – 1.17 0.041 788 7310 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.03 0.908 – 1.17 0.635 285 2654 all phecode
300 Anxiety disorders Mental Disorders 1.06 1.03 – 1.08 9.72e-07 15419 20850 all phecode
300.1 Anxiety disorder Mental Disorders 1.06 1.04 – 1.09 1.04e-07 14517 20855 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1.06 1.02 – 1.09 0.000808 5546 20512 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.07 1.01 – 1.14 0.0312 1360 11377 all phecode
300.13 Phobia Mental Disorders 1.08 1.01 – 1.15 0.0351 1051 9542 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.904 0.802 – 1.02 0.0947 328 3018 all phecode
300.4 Dysthymic disorder Mental Disorders 1.06 1.02 – 1.11 0.00757 2420 16552 all phecode
300.8 Acute reaction to stress Mental Disorders 1.04 0.938 – 1.14 0.492 504 4825 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.14 1.05 – 1.22 0.000978 843 7909 all phecode
301 Personality disorders Mental Disorders 1.12 1.02 – 1.24 0.0236 477 4539 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.1 0.962 – 1.26 0.162 254 2393 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.975 0.937 – 1.01 0.195 3700 13808 all phecode
302.1 Decreased libido Mental Disorders 0.926 0.838 – 1.02 0.138 447 4331 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.936 0.909 – 0.964 1.33e-05 6808 20043 all phecode
303.1 Dissociative disorder Mental Disorders 1.16 0.979 – 1.38 0.085 161 1573 all phecode
303.3 Psychogenic disorder Mental Disorders 0.925 0.898 – 0.954 5.26e-07 6487 19888 all phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.937 0.848 – 1.04 0.202 471 4623 all phecode
303.4 Somatoform disorder Mental Disorders 1.02 0.955 – 1.08 0.587 1177 11180 all phecode
304 Adjustment reaction Mental Disorders 1.04 0.998 – 1.07 0.0656 3888 20475 all phecode
305.2 Eating disorder Mental Disorders 1.33 1.23 – 1.43 5.51e-14 901 8329 all phecode
306 Other mental disorder Mental Disorders 1.03 0.98 – 1.09 0.23 1815 14133 all phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.08 0.985 – 1.19 0.0976 587 3527 all phecode
306.9 Tension headache Mental Disorders 1.02 0.939 – 1.1 0.678 753 7277 all phecode
312 Conduct disorders Mental Disorders 1.06 0.929 – 1.22 0.377 254 2501 all phecode
312.3 Impulse control disorder Mental Disorders 0.963 0.757 – 1.23 0.763 74 736 all phecode
313 Pervasive developmental disorders Mental Disorders 1.04 0.984 – 1.1 0.172 1571 14633 all phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1.03 0.976 – 1.1 0.255 1392 13190 all phecode
313.2 Tics and stuttering Mental Disorders 1.08 0.844 – 1.38 0.547 77 770 all phecode
313.3 Autism Mental Disorders 0.885 0.68 – 1.15 0.366 64 621 all phecode
315 Develomental delays and disorders Mental Disorders 1.07 0.984 – 1.16 0.113 684 6788 all phecode
315.1 Learning disorder Mental Disorders 1.12 0.902 – 1.38 0.311 87 860 all phecode
315.2 Speech and language disorder Mental Disorders 0.951 0.831 – 1.09 0.469 254 2539 all phecode
316 Substance addiction and disorders Mental Disorders 1.14 1.1 – 1.18 2.91e-12 3682 32680 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.978 0.897 – 1.07 0.607 634 6331 all phecode
317 Alcohol-related disorders Mental Disorders 1.06 1.01 – 1.1 0.00999 2525 22920 all phecode
317.1 Alcoholism Mental Disorders 1.05 0.998 – 1.1 0.0589 1986 19339 all phecode
317.11 Alcoholic liver damage Mental Disorders 1 0.902 – 1.11 0.965 408 4080 all phecode
318 Tobacco use disorder Mental Disorders 1.19 1.16 – 1.22 9.75e-44 8622 34842 all phecode
320 Meningitis Neurological 1.01 0.907 – 1.13 0.832 382 3820 all phecode
323 Encephalitis Neurological 1.07 0.909 – 1.25 0.437 181 1809 all phecode
323.8 Encephalitis, non-infectious Neurological 1.09 0.914 – 1.29 0.352 153 1527 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.13 0.997 – 1.29 0.0556 288 2880 all phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 1.02 0.76 – 1.37 0.889 53 530 all phecode
327 Sleep disorders Neurological 1.17 1.15 – 1.2 1.51e-51 14941 31602 all phecode
327.1 Hypersomnia Neurological 1.09 1.04 – 1.14 0.000776 2061 19110 all phecode
327.3 Sleep apnea Neurological 1.25 1.22 – 1.28 5.69e-75 10909 31304 all phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1.04 0.947 – 1.15 0.398 492 4784 all phecode
327.32 Obstructive sleep apnea Neurological 1.25 1.22 – 1.28 2.62e-65 8744 30530 all phecode
327.4 Insomnia Neurological 1.07 1.04 – 1.1 2.02e-05 5524 30960 all phecode
327.41 Organic or persistent insomnia Neurological 1.02 0.96 – 1.09 0.516 1265 12120 all phecode
327.5 Parasomnia Neurological 1.18 1.08 – 1.29 0.000243 604 5913 all phecode
327.6 Circadian rhythm sleep disorder Neurological 1.05 0.915 – 1.19 0.511 274 2666 all phecode
327.7 Sleep related movement disorders Neurological 1.15 1.1 – 1.22 6.06e-08 1786 17323 all phecode
327.71 Restless legs syndrome Neurological 1.17 1.11 – 1.24 3.6e-08 1570 15360 all phecode
327.72 Sleep related leg cramps Neurological 0.975 0.769 – 1.23 0.831 83 822 all phecode
331 Other cerebral degenerations Neurological 0.937 0.864 – 1.02 0.115 717 7024 all phecode
331.1 Hydrocephalus Neurological 0.943 0.831 – 1.07 0.362 284 2836 all phecode
331.9 Cerebral degeneration, unspecified Neurological 0.97 0.873 – 1.08 0.576 419 4026 all phecode
332 Parkinson's disease Neurological 0.91 0.818 – 1.01 0.0858 415 4128 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.05 1.01 – 1.1 0.0122 2868 26583 all phecode
333.1 Essential tremor Neurological 1.01 0.929 – 1.09 0.862 725 7163 all phecode
333.2 Myoclonus Neurological 1.14 0.969 – 1.34 0.113 159 1590 all phecode
333.4 Torsion dystonia Neurological 0.862 0.767 – 0.968 0.0121 352 3504 all phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 0.814 0.649 – 1.02 0.0734 89 890 all phecode
334 Degenerative disease of the spinal cord Neurological 1.1 1.03 – 1.18 0.00394 1058 10562 all phecode
334.1 Spinocerebellar disease Neurological 1.13 0.89 – 1.44 0.31 79 790 all phecode
334.2 Anterior horn cell disease Neurological 0.982 0.8 – 1.21 0.863 110 1080 all phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 0.917 0.71 – 1.18 0.504 71 693 all phecode
335 Multiple sclerosis Neurological 1.12 1 – 1.25 0.0404 396 3951 all phecode
337 Disorders of the autonomic nervous system Neurological 1.05 0.975 – 1.14 0.194 808 7413 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.1 0.987 – 1.24 0.0828 370 3164 all phecode
338 Pain Neurological 1.07 1.05 – 1.09 7.45e-13 20346 26417 all phecode
338.1 Acute pain Neurological 1.06 1.04 – 1.08 4.12e-08 15582 26313 all phecode
338.2 Chronic pain Neurological 1.12 1.09 – 1.15 4.58e-21 10994 26368 all phecode
339 Other headache syndromes Neurological 1.04 1.02 – 1.07 0.00158 9242 34658 all phecode
340 Migraine Neurological 1.04 1.01 – 1.07 0.00506 6708 30587 all phecode
340.1 Migrain with aura Neurological 1.04 1 – 1.08 0.0284 3624 23684 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.11 0.92 – 1.33 0.282 133 1330 all phecode
342 Hemiplegia Neurological 1.02 0.926 – 1.13 0.658 464 4607 all phecode
343 Infantile cerebral palsy Neurological 0.993 0.792 – 1.24 0.952 85 847 all phecode
344 Other paralytic syndromes Neurological 1.06 0.978 – 1.15 0.153 682 6808 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.03 0.986 – 1.07 0.194 2553 25307 all phecode
345.1 Epilepsy Neurological 1 0.925 – 1.08 0.976 747 7465 all phecode
345.11 Generalized convulsive epilepsy Neurological 0.994 0.864 – 1.14 0.931 233 2330 all phecode
345.12 Partial epilepsy Neurological 0.989 0.901 – 1.09 0.823 534 5335 all phecode
345.3 Convulsions Neurological 1.03 0.985 – 1.08 0.202 2396 23796 all phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.963 0.822 – 1.13 0.64 183 1824 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.998 0.943 – 1.06 0.948 1472 14587 all phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.9 0.74 – 1.09 0.288 120 1181 all phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 0.965 0.785 – 1.19 0.735 110 1100 all phecode
347 Cataplexy and narcolepsy Neurological 1.15 0.922 – 1.43 0.214 101 1010 all phecode
348 Other conditions of brain Neurological 1.07 1.02 – 1.13 0.006 1793 17894 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.06 0.985 – 1.14 0.122 905 9034 all phecode
348.4 Cerebral cysts Neurological 1.02 0.886 – 1.18 0.75 229 2290 all phecode
348.7 Coma Neurological 0.998 0.867 – 1.15 0.981 229 2275 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.09 1.01 – 1.18 0.0192 853 8479 all phecode
348.9 Other conditions of brain, NOS Neurological 0.986 0.943 – 1.03 0.545 2341 23287 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.06 0.992 – 1.14 0.0815 941 9385 all phecode
350 Abnormal movement Neurological 1.04 1.01 – 1.07 0.00597 6706 38762 all phecode
350.1 Abnormal involuntary movements Neurological 1.03 0.995 – 1.07 0.0885 3273 30524 all phecode
350.2 Abnormality of gait Neurological 1.05 1.01 – 1.09 0.00581 3920 30520 all phecode
350.3 Lack of coordination Neurological 0.952 0.891 – 1.02 0.148 1062 10554 all phecode
350.5 Abnormal reflex Neurological 1 0.862 – 1.17 0.959 200 1988 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.964 0.879 – 1.06 0.432 558 5576 all phecode
351 Other peripheral nerve disorders Neurological 1.1 1.07 – 1.13 6.35e-12 7401 34460 all phecode
352 Disorders of other cranial nerves Neurological 1.02 0.972 – 1.08 0.378 1714 17106 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.01 0.916 – 1.1 0.896 535 5344 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.06 0.983 – 1.15 0.129 783 7826 all phecode
353 Nerve root and plexus disorders Neurological 1.08 1.04 – 1.11 1.4e-05 4256 33369 all phecode
353.1 Nerve plexus lesions Neurological 1.09 0.978 – 1.22 0.118 390 3900 all phecode
353.2 Nerve root lesions Neurological 1.06 0.884 – 1.28 0.519 130 1287 all phecode
355 Complex regional/central pain syndrome Neurological 1.08 0.986 – 1.19 0.0937 531 5295 all phecode
355.1 Chronic pain syndrome Neurological 1.16 1.08 – 1.25 7.23e-05 843 8386 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.08 1.03 – 1.13 0.00103 2335 20731 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.11 1.06 – 1.15 1.61e-07 3472 29956 all phecode
358 Myoneural disorders Neurological 1.11 1.04 – 1.18 0.0015 1147 11391 all phecode
358.1 Myasthenia gravis Neurological 0.915 0.744 – 1.13 0.401 109 1082 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.971 0.91 – 1.04 0.38 1134 11274 all phecode
359.1 Muscular dystrophies Neurological 0.903 0.676 – 1.21 0.49 64 632 all phecode
359.2 Myopathy Neurological 0.981 0.918 – 1.05 0.578 1092 10843 all phecode
360 Disorders of the globe Sense Organs 0.901 0.746 – 1.09 0.276 131 1276 all phecode
360.2 Progressive myopia Sense Organs 0.781 0.597 – 1.02 0.0723 65 640 all phecode
361 Retinal detachments and defects Sense Organs 0.932 0.86 – 1.01 0.0872 733 7131 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.851 0.749 – 0.966 0.013 302 2962 all phecode
362 Other retinal disorders Sense Organs 0.987 0.95 – 1.03 0.521 3569 22997 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.958 0.913 – 1.01 0.0863 2172 15483 all phecode
362.21 Macular degeneration, dry Sense Organs 0.862 0.77 – 0.965 0.01 419 3438 all phecode
362.22 Macular degeneration, wet Sense Organs 0.996 0.828 – 1.2 0.97 148 1184 all phecode
362.23 Cystoid macular degeneration of retina Sense Organs 0.894 0.802 – 0.998 0.0453 408 3839 all phecode
362.26 Macular puckering of retina Sense Organs 0.944 0.88 – 1.01 0.107 976 8610 all phecode
362.27 Drusen (degenerative) of retina Sense Organs 0.89 0.804 – 0.985 0.0243 488 4558 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.963 0.914 – 1.01 0.155 1883 13955 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.06 0.985 – 1.13 0.122 976 8527 all phecode
362.31 Separation of retinal layers Sense Organs 0.967 0.869 – 1.07 0.531 413 4056 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.02 0.938 – 1.11 0.629 662 5933 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.874 0.782 – 0.977 0.0176 392 3787 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.924 0.795 – 1.07 0.304 215 2103 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.19 1.03 – 1.36 0.0162 241 2368 all phecode
362.9 Retinal edema Sense Organs 1.14 1.01 – 1.29 0.0298 324 2936 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.908 0.822 – 1 0.0561 492 4746 all phecode
363.3 Chorioretinal scars Sense Organs 0.843 0.749 – 0.949 0.00476 332 3184 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.972 0.91 – 1.04 0.402 1132 10772 all phecode
364.1 Corneal opacity Sense Organs 0.962 0.863 – 1.07 0.486 394 3846 all phecode
364.2 Corneal edema Sense Organs 1.1 0.909 – 1.33 0.328 123 1208 all phecode
364.4 Corneal degenerations Sense Organs 0.997 0.895 – 1.11 0.962 402 3962 all phecode
364.41 Keratoconus Sense Organs 0.762 0.592 – 0.98 0.0344 75 739 all phecode
364.5 Corneal dystrophy Sense Organs 0.978 0.885 – 1.08 0.668 502 4682 all phecode
364.51 Fuchs' dystrophy Sense Organs 0.902 0.786 – 1.04 0.144 266 2521 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.912 0.727 – 1.14 0.421 91 885 all phecode
365 Glaucoma Sense Organs 0.968 0.927 – 1.01 0.142 2672 21326 all phecode
365.1 Open-angle glaucoma Sense Organs 0.935 0.86 – 1.02 0.11 705 6491 all phecode
365.11 Primary open angle glaucoma Sense Organs 0.913 0.819 – 1.02 0.104 403 3681 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.988 0.855 – 1.14 0.871 251 2370 all phecode
366 Cataract Sense Organs 0.984 0.957 – 1.01 0.242 8611 28043 all phecode
366.1 Nonsenile Cataract Sense Organs 0.94 0.808 – 1.09 0.426 207 1979 all phecode
366.2 Senile cataract Sense Organs 0.968 0.937 – 1 0.0539 5480 24980 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.973 0.949 – 0.997 0.031 8967 37779 all phecode
367.1 Myopia Sense Organs 0.946 0.916 – 0.977 0.00069 5014 34677 all phecode
367.2 Astigmatism Sense Organs 0.938 0.906 – 0.971 0.000289 4161 32463 all phecode
367.8 Hypermetropia Sense Organs 0.947 0.902 – 0.995 0.0294 2039 18599 all phecode
367.9 Blindness and low vision Sense Organs 1.06 1 – 1.13 0.0458 1277 12356 all phecode
368 Visual disturbances Sense Organs 1.02 0.989 – 1.05 0.229 5715 39599 all phecode
368.1 Amblyopia Sense Organs 1.07 0.985 – 1.17 0.109 651 6479 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.01 0.948 – 1.08 0.709 1087 10786 all phecode
368.3 Anisometropia Sense Organs 0.844 0.728 – 0.978 0.0239 219 2168 all phecode
368.4 Visual field defects Sense Organs 1.01 0.946 – 1.08 0.793 1132 11173 all phecode
368.9 Subjective visual disturbances Sense Organs 1.02 0.958 – 1.09 0.493 1070 10620 all phecode
368.91 Psychophysical visual disturbances Sense Organs 1.25 1.03 – 1.52 0.0269 120 1171 all phecode
369 Infection of the eye Sense Organs 0.948 0.912 – 0.986 0.00713 3185 28240 all phecode
369.2 Eye infection, viral Sense Organs 0.924 0.837 – 1.02 0.118 502 4954 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.955 0.915 – 0.996 0.0305 2716 24970 all phecode
370 Keratitis Sense Organs 0.91 0.858 – 0.966 0.00178 1365 13169 all phecode
370.1 Corneal ulcer Sense Organs 0.903 0.782 – 1.04 0.163 223 2194 all phecode
370.2 Superficial keratitis Sense Organs 0.901 0.821 – 0.989 0.0284 546 5393 all phecode
370.3 Keratoconjunctivitis Sense Organs 0.971 0.892 – 1.06 0.5 649 6263 all phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.945 0.799 – 1.12 0.504 179 1677 all phecode
371 Inflammation of the eye Sense Organs 0.944 0.913 – 0.977 0.000889 4414 32310 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.982 0.894 – 1.08 0.708 541 5278 all phecode
371.2 Conjunctivitis, noninfectious Sense Organs 0.959 0.892 – 1.03 0.263 906 8939 all phecode
371.21 Allergic conjunctivitis Sense Organs 0.953 0.88 – 1.03 0.233 756 7515 all phecode
371.3 Inflammation of eyelids Sense Organs 0.935 0.9 – 0.971 0.000533 3398 26983 all phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 0.823 0.679 – 0.998 0.0478 133 1291 all phecode
372 Disorders of conjunctiva Sense Organs 0.941 0.881 – 1 0.0652 1118 10728 all phecode
374 Other disorders of eyelids Sense Organs 0.926 0.889 – 0.965 0.00025 2940 24188 all phecode
374.1 Ectropion or entropion Sense Organs 0.86 0.774 – 0.956 0.00501 431 4084 all phecode
374.2 Lagophthalmos Sense Organs 0.979 0.849 – 1.13 0.768 235 2335 all phecode
374.3 Ptosis of eyelid Sense Organs 0.936 0.877 – 1 0.0501 1102 10734 all phecode
374.6 Dermatochalasis Sense Organs 0.954 0.891 – 1.02 0.178 1040 9720 all phecode
375 Disorders of lacrimal system Sense Organs 0.972 0.937 – 1.01 0.139 3694 26045 all phecode
375.1 Dry eyes Sense Organs 0.97 0.936 – 1.01 0.0985 4040 26751 all phecode
375.2 Epiphora Sense Organs 0.982 0.883 – 1.09 0.73 442 4354 all phecode
376 Disorders of the orbit Sense Organs 0.975 0.869 – 1.09 0.662 352 3508 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.08 1 – 1.16 0.0443 913 9021 all phecode
377.1 Optic atrophy Sense Organs 1.02 0.889 – 1.16 0.82 283 2793 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.08 0.991 – 1.19 0.0786 585 5775 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.968 0.911 – 1.03 0.299 1275 12460 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.98 0.909 – 1.06 0.6 828 8130 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1 0.85 – 1.18 0.974 170 1686 all phecode
378.5 Paralytic strabismus Sense Organs 0.899 0.802 – 1.01 0.0676 349 3437 all phecode
379 Other disorders of eye Sense Organs 0.955 0.924 – 0.987 0.00548 5046 29999 all phecode
379.1 Scleritis and episcleritis Sense Organs 0.85 0.719 – 1.01 0.0589 176 1743 all phecode
379.2 Disorders of vitreous body Sense Organs 0.948 0.913 – 0.985 0.00593 3634 23186 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.855 0.71 – 1.03 0.0995 135 1258 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.01 0.89 – 1.15 0.864 287 2833 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.05 0.932 – 1.19 0.401 304 2948 all phecode
379.51 Pigmentary iris degeneration Sense Organs 0.822 0.638 – 1.06 0.131 77 731 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1 0.941 – 1.07 0.887 1129 11130 all phecode
380 Disorders of external ear Sense Organs 0.919 0.878 – 0.963 0.00039 2242 20393 all phecode
380.1 Otitis externa Sense Organs 0.998 0.944 – 1.06 0.95 1469 14580 all phecode
380.4 Impacted cerumen Sense Organs 0.917 0.878 – 0.957 6.58e-05 2648 23557 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1 0.968 – 1.03 0.967 4255 36417 all phecode
381.1 Otitis media Sense Organs 1.04 1 – 1.08 0.0387 3079 29813 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.05 1.01 – 1.1 0.0237 2610 25602 all phecode
381.2 Eustachian tube disorders Sense Organs 0.921 0.875 – 0.97 0.00167 1816 17827 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.1 0.928 – 1.3 0.273 153 1530 all phecode
381.9 Otorrhea Sense Organs 1.14 1.02 – 1.27 0.0239 372 3713 all phecode
382 Otalgia Sense Organs 1.04 0.985 – 1.09 0.165 1884 18673 all phecode
383 Otosclerosis Sense Organs 0.93 0.77 – 1.12 0.454 124 1240 all phecode
384 Other disorders of tympanic membrane Sense Organs 1 0.912 – 1.1 0.979 516 5156 all phecode
384.1 Myringitis Sense Organs 0.945 0.702 – 1.27 0.707 51 502 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.01 0.908 – 1.12 0.856 403 4029 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.01 0.914 – 1.12 0.806 432 4320 all phecode
385.3 Cholesteatoma Sense Organs 1.03 0.907 – 1.17 0.658 277 2770 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.947 0.782 – 1.15 0.579 118 1180 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.02 0.97 – 1.07 0.443 1882 18186 all phecode
386.1 Meniere's disease Sense Organs 1.04 0.923 – 1.18 0.498 319 3156 all phecode
386.2 Peripheral or central vertigo Sense Organs 1.02 0.965 – 1.08 0.49 1586 15423 all phecode
386.21 Central origin vertigo Sense Organs 1.03 0.969 – 1.1 0.328 1208 11844 all phecode
386.3 Labyrinthitis Sense Organs 1.02 0.966 – 1.08 0.443 1482 14530 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.03 1.01 – 1.06 0.0194 6933 38286 all phecode
388 Other disorders of ear Sense Organs 0.96 0.895 – 1.03 0.255 960 9501 all phecode
389 Hearing loss Sense Organs 0.983 0.958 – 1.01 0.199 8182 38069 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.943 0.91 – 0.976 0.000909 4107 29258 all phecode
389.2 Conductive hearing loss Sense Organs 0.971 0.904 – 1.04 0.42 905 9042 all phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 0.945 0.807 – 1.11 0.487 192 1808 all phecode
389.4 Tinnitus Sense Organs 0.927 0.885 – 0.97 0.00099 2291 22130 all phecode
389.5 Disorders of acoustic nerve Sense Organs 1.12 0.93 – 1.36 0.227 124 1229 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.05 0.993 – 1.11 0.086 1458 13732 all phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 1.06 0.945 – 1.19 0.318 350 3415 all phecode
394.2 Mitral valve disease Circulatory System 1.03 0.928 – 1.14 0.616 462 4560 all phecode
394.3 Aortic valve disease Circulatory System 1.09 0.919 – 1.28 0.33 176 1691 all phecode
394.4 Acute rheumatic heart disease Circulatory System 1.02 0.77 – 1.36 0.874 55 546 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.07 0.98 – 1.17 0.127 587 5739 all phecode
395 Heart valve disorders Circulatory System 1.02 0.98 – 1.05 0.384 3976 28748 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.954 0.91 – 0.999 0.0475 2175 20441 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.08 1.03 – 1.14 0.00124 2060 17194 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.06 0.958 – 1.16 0.274 493 4864 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.03 0.834 – 1.26 0.809 108 1080 all phecode
395.6 Heart valve replaced Circulatory System 1.09 1.02 – 1.16 0.0107 1177 10833 all phecode
396 Abnormal heart sounds Circulatory System 1.02 0.991 – 1.06 0.154 4718 34395 all phecode
401 Hypertension Circulatory System 1.29 1.26 – 1.32 2.98e-112 23317 23367 all phecode
401.1 Essential hypertension Circulatory System 1.29 1.26 – 1.32 2.16e-113 23158 23364 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.42 1.36 – 1.48 2.67e-57 3503 14616 all phecode
401.21 Hypertensive heart disease Circulatory System 1.32 1.22 – 1.42 1.07e-12 893 6607 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.41 1.34 – 1.48 2.62e-44 2584 13072 all phecode
401.3 Other hypertensive complications Circulatory System 1.29 1.23 – 1.35 2.07e-28 2679 15833 all phecode
411 Ischemic Heart Disease Circulatory System 1.15 1.12 – 1.18 1.33e-25 8807 30299 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.16 1.08 – 1.25 3.11e-05 937 8574 all phecode
411.2 Myocardial infarction Circulatory System 1.2 1.15 – 1.25 1.12e-20 3594 21716 all phecode
411.3 Angina pectoris Circulatory System 1.18 1.13 – 1.23 5.78e-13 2485 18304 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.15 1.12 – 1.19 8.18e-23 7555 27492 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.13 0.948 – 1.36 0.169 156 1529 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.16 1.13 – 1.2 3.36e-22 6331 25741 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.22 1.1 – 1.35 0.000132 442 4211 all phecode
414 Other forms of chronic heart disease Circulatory System 1.12 1.08 – 1.17 3.94e-08 3101 22616 all phecode
414.2 ASCVD Circulatory System 1.12 1.03 – 1.21 0.00749 718 6816 all phecode
415 Pulmonary heart disease Circulatory System 1.14 1.1 – 1.19 2.62e-12 3366 30208 all phecode
415.1 Acute pulmonary heart disease Circulatory System 1.13 1.07 – 1.18 3.37e-06 1912 19014 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.13 1.07 – 1.18 3.36e-06 1906 18953 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.16 1.1 – 1.22 7.99e-09 1808 17605 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.12 1.03 – 1.22 0.00542 706 7032 all phecode
416 Cardiomegaly Circulatory System 1.09 1.03 – 1.16 0.00528 1254 12372 all phecode
418 Nonspecific chest pain Circulatory System 1.05 1.03 – 1.08 3.04e-06 12650 33952 all phecode
418.1 Precordial pain Circulatory System 1.05 0.988 – 1.11 0.126 1471 13782 all phecode
420 Carditis Circulatory System 1.07 1.01 – 1.13 0.0195 1588 15680 all phecode
420.1 Myocarditis Circulatory System 1.16 0.935 – 1.45 0.174 97 958 all phecode
420.2 Pericarditis Circulatory System 1.07 0.991 – 1.15 0.084 842 8402 all phecode
420.21 Acute pericarditis Circulatory System 1.24 1.05 – 1.46 0.00926 177 1764 all phecode
420.22 Chronic pericarditis Circulatory System 1.22 0.993 – 1.49 0.0581 117 1153 all phecode
420.3 Endocarditis Circulatory System 1.1 1.02 – 1.19 0.0196 764 7535 all phecode
425 Cardiomyopathy Circulatory System 1.13 1.07 – 1.18 1.42e-06 2078 19881 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.14 1.08 – 1.19 3.52e-07 1989 19025 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.02 0.881 – 1.19 0.759 208 2050 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.06 0.911 – 1.23 0.456 201 1992 all phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.03 0.912 – 1.17 0.628 317 3170 all phecode
425.8 Other cardiomyopathy Circulatory System 1.15 0.915 – 1.45 0.23 95 931 all phecode
426 Cardiac conduction disorders Circulatory System 1.08 1.05 – 1.11 4.66e-10 12327 25440 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.14 1.09 – 1.21 5.85e-07 1903 11501 all phecode
426.21 First degree AV block Circulatory System 1.13 1.06 – 1.2 0.000192 1313 8899 all phecode
426.22 Mobitz II AV block Circulatory System 1.04 0.79 – 1.38 0.76 64 553 all phecode
426.23 Second degree AV block Circulatory System 1.07 0.922 – 1.25 0.364 216 1925 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.08 0.978 – 1.2 0.126 461 3823 all phecode
426.25 Other heart block Circulatory System 1.07 0.921 – 1.24 0.374 203 1803 all phecode
426.3 Bundle branch block Circulatory System 1.08 1.03 – 1.14 0.000778 2306 13999 all phecode
426.31 Right bundle branch block Circulatory System 1.08 1.02 – 1.14 0.0108 1423 10758 all phecode
426.32 Left bundle branch block Circulatory System 1.12 1.04 – 1.2 0.0019 969 8110 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.05 0.831 – 1.33 0.679 82 820 all phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.08 1.05 – 1.1 9.73e-09 10577 25186 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.1 1.01 – 1.2 0.0246 679 6650 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.1 1.04 – 1.16 0.000416 1754 11536 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.13 1.05 – 1.2 0.000399 1171 8184 all phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.1 1.02 – 1.19 0.00961 846 7320 all phecode
427 Cardiac dysrhythmias Circulatory System 1.05 1.03 – 1.07 3.24e-06 17397 25735 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.05 1 – 1.09 0.0483 2474 18178 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.05 0.992 – 1.11 0.094 1595 14293 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.08 1.01 – 1.15 0.0178 1181 9915 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.09 1.06 – 1.13 3.27e-07 5313 18688 all phecode
427.21 Atrial fibrillation Circulatory System 1.09 1.05 – 1.13 7.28e-07 5188 18409 all phecode
427.22 Atrial flutter Circulatory System 1.08 1.02 – 1.14 0.00592 1693 11042 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.06 1.03 – 1.08 5.87e-05 8688 25552 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.05 0.959 – 1.16 0.275 536 5233 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.906 0.784 – 1.05 0.183 216 2118 all phecode
427.42 Cardiac arrest Circulatory System 1.09 0.979 – 1.21 0.114 410 4034 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.04 1.01 – 1.07 0.0093 6905 25457 all phecode
427.6 Premature beats Circulatory System 1.02 0.975 – 1.07 0.387 2359 16248 all phecode
427.61 Supraventricular premature beats Circulatory System 1.08 0.99 – 1.17 0.0836 670 6287 all phecode
427.7 Tachycardia NOS Circulatory System 1.1 1.06 – 1.13 1.25e-08 5124 25531 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.07 0.998 – 1.16 0.0574 912 7501 all phecode
427.9 Palpitations Circulatory System 0.991 0.958 – 1.03 0.62 4430 24505 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.22 1.18 – 1.26 4.07e-28 4300 23663 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.23 1.18 – 1.27 2.31e-26 3756 22446 all phecode
428.2 Heart failure NOS Circulatory System 1.25 1.2 – 1.3 1.09e-30 3701 21722 all phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.2 1.14 – 1.27 4.41e-12 1765 14476 all phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.29 1.22 – 1.37 5.16e-20 1648 13395 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.07 1.04 – 1.09 1.62e-08 12635 32504 all phecode
429.1 Heart transplant/surgery Circulatory System 1.08 1.02 – 1.15 0.0117 1219 11696 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.09 1.06 – 1.13 3.51e-09 6322 29232 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.06 1.03 – 1.09 3.35e-06 9650 32421 all phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.12 1.03 – 1.21 0.00534 723 7072 all phecode
430 Intracranial hemorrhage Circulatory System 0.956 0.885 – 1.03 0.253 789 7842 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.01 0.884 – 1.16 0.872 261 2610 all phecode
430.2 Intracerebral hemorrhage Circulatory System 0.991 0.885 – 1.11 0.877 368 3671 all phecode
430.3 Subdural hemorrhage Circulatory System 0.888 0.78 – 1.01 0.0736 272 2680 all phecode
433 Cerebrovascular disease Circulatory System 1.09 1.06 – 1.13 1.53e-08 5463 32242 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.09 1.04 – 1.15 0.000362 1978 16212 all phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.21 1.05 – 1.38 0.00716 260 2517 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.12 0.883 – 1.43 0.343 80 789 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.12 1.07 – 1.17 1.02e-06 2437 21732 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.11 1.07 – 1.17 2.24e-06 2357 21103 all phecode
433.3 Cerebral ischemia Circulatory System 1.07 1.02 – 1.11 0.00267 2780 22868 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.08 1.03 – 1.13 0.000961 2409 20762 all phecode
433.5 Cerebral aneurysm Circulatory System 1.02 0.928 – 1.13 0.633 474 4724 all phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.12 1.01 – 1.24 0.0255 464 4518 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.14 1.05 – 1.24 0.00138 695 6822 all phecode
440 Atherosclerosis Circulatory System 1.15 1.1 – 1.2 2.26e-09 2477 19724 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.05 0.91 – 1.21 0.512 231 2291 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.14 1.08 – 1.21 3.92e-06 1516 13532 all phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.26 1.1 – 1.43 0.000562 274 2669 all phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.14 1.06 – 1.22 0.000234 1040 9647 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.2 1.11 – 1.29 2.06e-06 846 8124 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.04 0.949 – 1.15 0.376 515 5115 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.02 0.895 – 1.17 0.724 240 2387 all phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.04 0.877 – 1.24 0.637 154 1536 all phecode
442 Other aneurysm Circulatory System 1.09 1.04 – 1.14 6.97e-05 2779 21466 all phecode
442.1 Aortic aneurysm Circulatory System 1.09 1.04 – 1.15 0.000372 2054 16492 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.08 1.01 – 1.15 0.019 1189 10558 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.17 1 – 1.36 0.0486 202 2002 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.02 0.87 – 1.2 0.802 179 1765 all phecode
442.4 Arterial dissection Circulatory System 0.984 0.841 – 1.15 0.838 184 1840 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.1 0.983 – 1.22 0.0998 399 3978 all phecode
443 Peripheral vascular disease Circulatory System 1.09 1.05 – 1.14 1.34e-05 3086 24814 all phecode
443.1 Raynaud's syndrome Circulatory System 0.882 0.814 – 0.955 0.00199 742 7390 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.4 1.2 – 1.62 1.08e-05 220 2087 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.09 1.04 – 1.14 0.00012 2557 21985 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.16 1.11 – 1.22 1.56e-10 2341 18862 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.12 1.04 – 1.21 0.00274 848 8423 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.03 0.913 – 1.17 0.622 313 3099 all phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 1.05 0.884 – 1.25 0.57 155 1548 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.997 0.9 – 1.1 0.951 460 4559 all phecode
446.4 Wegener's granulomatosis Circulatory System 0.827 0.671 – 1.02 0.0755 109 1075 all phecode
446.5 Giant cell arteritis Circulatory System 0.827 0.651 – 1.05 0.122 79 749 all phecode
446.9 Arteritis NOS Circulatory System 1.04 0.913 – 1.18 0.574 289 2876 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.08 1.04 – 1.13 0.000266 2647 22765 all phecode
447.1 Stricture of artery Circulatory System 1.14 1.04 – 1.25 0.00738 523 5163 all phecode
447.7 Aortic ectasia Circulatory System 1.02 0.949 – 1.1 0.542 804 7938 all phecode
448 Disease of capillaries Circulatory System 0.844 0.793 – 0.898 9.1e-08 1237 12127 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.07 1.02 – 1.13 0.00376 2104 20985 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.06 0.978 – 1.15 0.157 738 7355 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.09 0.945 – 1.25 0.24 244 2437 all phecode
452 Other venous embolism and thrombosis Circulatory System 1.12 1.08 – 1.15 7.36e-12 4957 29867 all phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1.02 0.898 – 1.16 0.736 276 2747 all phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1.12 1.08 – 1.16 5.89e-09 3260 26940 all phecode
452.8 Postphlebitic syndrome Circulatory System 1.17 0.985 – 1.38 0.075 154 1529 all phecode
453 Chronic venous hypertension Circulatory System 1.17 1.01 – 1.36 0.0343 220 2168 all phecode
454 Varicose veins Circulatory System 1.07 1.02 – 1.11 0.00226 2827 24555 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1.09 1.05 – 1.14 9.02e-05 2469 21426 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.1 1.04 – 1.17 0.000483 1565 15056 all phecode
455 Hemorrhoids Circulatory System 0.966 0.937 – 0.995 0.0232 5799 29818 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.09 1.05 – 1.13 3.34e-05 3097 24898 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.11 1.06 – 1.16 2.86e-05 2095 15309 all phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.14 1.01 – 1.28 0.0297 324 3221 all phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.11 1.05 – 1.16 8.12e-05 1973 14689 all phecode
458 Hypotension Circulatory System 1.11 1.08 – 1.15 1.09e-10 5091 32185 all phecode
458.1 Orthostatic hypotension Circulatory System 1.07 1.01 – 1.14 0.0174 1344 12938 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.13 1.06 – 1.2 0.000309 1109 11012 all phecode
458.9 Hypotension NOS Circulatory System 1.11 1.07 – 1.15 4.13e-10 4618 31186 all phecode
459 Other disorders of circulatory system Circulatory System 1.09 1.07 – 1.12 2.26e-11 7825 34792 all phecode
459.1 Hemorrhage NOS Circulatory System 1.02 0.948 – 1.1 0.566 834 8215 all phecode
459.7 Blood vessel replaced Circulatory System 1.17 1.1 – 1.24 4.79e-07 1305 13023 all phecode
459.9 Circulatory disease NEC Circulatory System 1.1 1.07 – 1.13 1.14e-10 6706 33592 all phecode
464 Acute sinusitis Respiratory 0.965 0.934 – 0.996 0.0296 4792 32137 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.969 0.946 – 0.993 0.0114 9601 35915 all phecode
465.2 Acute pharyngitis Respiratory 0.956 0.926 – 0.986 0.00405 5310 32365 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.02 0.921 – 1.13 0.69 443 4428 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.914 0.868 – 0.962 0.000582 1797 17640 all phecode
471 Nasal polyps Respiratory 0.941 0.861 – 1.03 0.178 592 5881 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.978 0.929 – 1.03 0.405 1797 16986 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1.01 0.973 – 1.05 0.529 2983 25244 all phecode
473.1 Chronic laryngitis Respiratory 1.1 0.858 – 1.42 0.441 68 674 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1 0.919 – 1.09 0.981 628 6254 all phecode
473.4 Voice disturbance Respiratory 1.02 0.971 – 1.06 0.483 2336 21975 all phecode
474 Acute and chronic tonsillitis Respiratory 1.05 0.98 – 1.13 0.154 880 7892 all phecode
474.1 Acute tonsillitis Respiratory 0.894 0.794 – 1.01 0.0638 335 3181 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.09 1 – 1.18 0.0424 700 6445 all phecode
475 Chronic sinusitis Respiratory 0.964 0.931 – 0.997 0.0318 4378 27891 all phecode
475.9 Postnasal drip Respiratory 0.908 0.845 – 0.977 0.0095 922 9017 all phecode
476 Allergic rhinitis Respiratory 0.986 0.964 – 1.01 0.202 12687 28117 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.07 1 – 1.14 0.0439 1150 11318 all phecode
478 Throat pain Respiratory 0.979 0.881 – 1.09 0.684 426 4195 all phecode
479 Other upper respiratory disease Respiratory 0.999 0.969 – 1.03 0.953 5627 28048 all phecode
480 Pneumonia Respiratory 1.08 1.05 – 1.11 2.39e-07 5947 37034 all phecode
480.1 Bacterial pneumonia Respiratory 1.09 1.02 – 1.16 0.0116 1155 11495 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.1 1.01 – 1.21 0.0386 568 5644 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.05 0.878 – 1.25 0.604 153 1523 all phecode
480.13 MRSA pneumonia Respiratory 1.13 0.932 – 1.38 0.211 117 1165 all phecode
480.2 Viral pneumonia Respiratory 1.12 0.966 – 1.31 0.131 202 1992 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.07 0.907 – 1.27 0.41 159 1590 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.1 0.92 – 1.33 0.286 135 1312 all phecode
481 Influenza Respiratory 1.02 0.962 – 1.08 0.503 1355 13284 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.04 0.998 – 1.08 0.065 3412 29871 all phecode
495 Asthma Respiratory 1.13 1.1 – 1.16 1.34e-20 8671 33569 all phecode
495.1 Chronic obstructive asthma Respiratory 1.2 1.08 – 1.34 0.000911 397 3925 all phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 1.17 0.914 – 1.51 0.209 81 802 all phecode
495.2 Asthma with exacerbation Respiratory 1.08 1.03 – 1.14 0.00353 1629 16033 all phecode
496 Chronic airway obstruction Respiratory 1.18 1.14 – 1.22 1.03e-24 5343 28343 all phecode
496.1 Emphysema Respiratory 1.14 1.09 – 1.2 3.37e-08 2134 19414 all phecode
496.2 Chronic bronchitis Respiratory 1.23 1.18 – 1.27 4.08e-30 4128 26624 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.24 1.19 – 1.28 5.64e-30 3747 25467 all phecode
496.3 Bronchiectasis Respiratory 0.974 0.888 – 1.07 0.575 549 5453 all phecode
497 Bronchitis Respiratory 1.08 1.03 – 1.14 0.00178 1946 18824 all phecode
498 Acute bronchospasm Respiratory 1.29 1.17 – 1.43 3.86e-07 496 4943 all phecode
499 Cystic fibrosis Respiratory 0.977 0.819 – 1.17 0.795 151 1510 all phecode
500 Lung disease due to external agents Respiratory 1.12 1.02 – 1.22 0.0201 557 5551 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.05 0.842 – 1.31 0.655 92 920 all phecode
500.2 Pneumoconiosis Respiratory 1.25 0.987 – 1.58 0.0645 78 764 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.09 0.999 – 1.19 0.0516 634 6225 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.06 0.98 – 1.14 0.147 815 8076 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.18 1.1 – 1.28 1.21e-05 835 8243 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.07 0.982 – 1.18 0.119 595 5878 all phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 0.996 0.881 – 1.13 0.954 311 3084 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.1 1.04 – 1.16 0.000428 1638 15749 all phecode
506 Empyema and pneumothorax Respiratory 1.08 1.04 – 1.12 0.000284 2894 25235 all phecode
507 Pleurisy; pleural effusion Respiratory 1.09 1.05 – 1.14 1.78e-05 2916 26208 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.1 1.05 – 1.15 1.67e-05 2382 22588 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.14 1.1 – 1.18 8.69e-13 4032 29477 all phecode
509.1 Respiratory failure Respiratory 1.16 1.1 – 1.22 5.42e-09 1937 18949 all phecode
509.2 Respiratory insufficiency Respiratory 1.13 1.06 – 1.2 0.000274 1174 11679 all phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.11 1.06 – 1.17 7.64e-05 1689 16489 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.19 1.13 – 1.25 7.56e-11 1741 17249 all phecode
510 Other diseases of lung Respiratory 1.03 1 – 1.06 0.0518 5503 35907 all phecode
510.2 Lung transplant Respiratory 0.957 0.814 – 1.13 0.6 176 1757 all phecode
512 Other symptoms of respiratory system Respiratory 1.08 1.05 – 1.1 4.65e-13 18621 28154 all phecode
512.1 Wheezing Respiratory 1.21 1.14 – 1.28 2.41e-10 1409 13516 all phecode
512.2 Painful respiration Respiratory 1.05 1 – 1.1 0.0315 2309 21263 all phecode
512.3 Abnormal chest sounds Respiratory 0.967 0.854 – 1.1 0.599 291 2845 all phecode
512.7 Shortness of breath Respiratory 1.13 1.1 – 1.16 1.68e-22 10034 28081 all phecode
512.8 Cough Respiratory 1.07 1.04 – 1.1 1.61e-07 9501 28148 all phecode
512.9 Other dyspnea Respiratory 1.11 1.08 – 1.13 1.84e-16 10804 28104 all phecode
513 Respiratory abnormalities Respiratory 1.11 1.09 – 1.14 1.42e-21 12932 33822 all phecode
513.3 Hypoventilation Respiratory 1.21 1.12 – 1.3 5.44e-07 880 8646 all phecode
513.31 Apnea Respiratory 1.09 0.985 – 1.2 0.0979 462 4607 all phecode
513.32 Orthopnea Respiratory 1.26 1.09 – 1.45 0.00193 220 2160 all phecode
513.4 Hyperventilation Respiratory 1.27 1.15 – 1.39 1.54e-06 515 5124 all phecode
513.8 Disorders of diaphragm Respiratory 1.03 0.898 – 1.18 0.676 258 2557 all phecode
514 Abnormal findings examination of lungs Respiratory 1.05 1.01 – 1.08 0.00429 5365 34834 all phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 0.927 0.81 – 1.06 0.271 258 2580 all phecode
514.2 Solitary pulmonary nodule Respiratory 1.05 1.01 – 1.1 0.0115 3018 27338 all phecode
516 Abnormal sputum Respiratory 1.09 1.01 – 1.18 0.0301 735 7332 all phecode
516.1 Hemoptysis Respiratory 1.11 1.02 – 1.21 0.0185 611 6080 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.07 1.04 – 1.1 3.59e-06 6458 39057 all phecode
519.1 Tracheostomy complications Respiratory 1.23 1.07 – 1.43 0.005 214 2136 all phecode
519.2 Respiratory complications Respiratory 1.03 0.933 – 1.14 0.528 445 4430 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.02 0.962 – 1.07 0.569 1588 15787 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.07 1.04 – 1.11 1.74e-05 4706 34489 all phecode
520 Disorders of tooth development Digestive 1.02 0.917 – 1.14 0.67 369 3690 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.22 1.03 – 1.44 0.0193 165 1642 all phecode
520.2 Disturbances in tooth eruption Digestive 0.946 0.821 – 1.09 0.439 218 2172 all phecode
521 Diseases of hard tissues of teeth Digestive 1.17 1.09 – 1.26 1e-05 898 8954 all phecode
521.1 Dental caries Digestive 1.18 1.1 – 1.28 6.45e-06 837 8349 all phecode
521.2 Dental abrasion, erosion and attrition Digestive 1.08 0.818 – 1.44 0.572 52 510 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.25 1.14 – 1.37 2.99e-06 535 5340 all phecode
522.5 Periapical abscess Digestive 1.28 1.16 – 1.41 1.61e-06 459 4583 all phecode
523 Gingival and periodontal diseases Digestive 1.17 1.08 – 1.27 0.000102 718 7180 all phecode
523.1 Gingivitis Digestive 1.06 0.888 – 1.27 0.517 142 1418 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.24 1.11 – 1.39 0.000106 364 3636 all phecode
523.31 Acute periodontitis Digestive 1.25 1.11 – 1.41 0.000281 311 3109 all phecode
523.32 Chronic periodontitis Digestive 1.17 0.968 – 1.42 0.104 122 1204 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.825 0.735 – 0.926 0.00113 363 3630 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.798 0.691 – 0.922 0.00215 220 2200 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.16 1.09 – 1.24 1.24e-05 1039 10382 all phecode
525.1 Loss of teeth or edentulism Digestive 1.12 1 – 1.25 0.0471 374 3731 all phecode
526 Diseases of the jaws Digestive 0.94 0.901 – 0.98 0.00359 2680 26455 all phecode
526.1 Cysts of the jaws Digestive 0.921 0.805 – 1.05 0.231 247 2470 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.765 0.664 – 0.882 0.000216 241 2383 all phecode
526.4 Temporomandibular joint disorders Digestive 0.913 0.863 – 0.966 0.00147 1504 15025 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.917 0.861 – 0.977 0.00739 1187 11858 all phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 0.894 0.825 – 0.968 0.00603 741 7400 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.987 0.87 – 1.12 0.832 287 2864 all phecode
526.8 Exostosis of jaw Digestive 1.15 0.85 – 1.56 0.365 53 521 all phecode
526.9 Jaw disease NOS Digestive 0.941 0.854 – 1.04 0.226 487 4867 all phecode
527 Diseases of the salivary glands Digestive 1.04 0.986 – 1.09 0.16 1781 17771 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.03 0.785 – 1.35 0.844 58 579 all phecode
527.2 Sialoadenitis Digestive 1.08 0.97 – 1.21 0.159 394 3936 all phecode
527.7 Disturbance of salivary secretion Digestive 1.01 0.943 – 1.08 0.756 952 9481 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.19 1.03 – 1.36 0.0145 254 2540 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.98 0.939 – 1.02 0.341 2643 26197 all phecode
528.1 Stomatitis and mucositis Digestive 0.955 0.877 – 1.04 0.279 668 6657 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.988 0.85 – 1.15 0.871 211 2110 all phecode
528.12 Oral aphthae Digestive 0.969 0.839 – 1.12 0.676 215 2137 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.18 1.03 – 1.35 0.0209 235 2338 all phecode
528.4 Cysts of oral soft tissues Digestive 0.793 0.653 – 0.962 0.0189 124 1229 all phecode
528.41 Cyst of the salivary gland Digestive 0.916 0.715 – 1.17 0.491 77 760 all phecode
528.5 Diseases of lips Digestive 0.995 0.899 – 1.1 0.925 462 4602 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1 0.835 – 1.2 0.979 137 1370 all phecode
528.7 Sialolithiasis Digestive 1.15 0.965 – 1.36 0.12 163 1623 all phecode
529 Diseases and other conditions of the tongue Digestive 1.11 1.02 – 1.21 0.0133 690 6878 all phecode
529.1 Glossitis Digestive 1.13 0.929 – 1.36 0.227 129 1281 all phecode
529.6 Glossodynia Digestive 1.13 0.957 – 1.33 0.153 168 1652 all phecode
530 Diseases of esophagus Digestive 1.12 1.1 – 1.15 6.99e-28 17081 27931 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.12 1.1 – 1.15 1.48e-27 16572 27931 all phecode
530.11 GERD Digestive 1.12 1.1 – 1.15 8.11e-28 16143 27929 all phecode
530.12 Ulcer of esophagus Digestive 1.07 0.962 – 1.2 0.209 400 3983 all phecode
530.13 Barrett's esophagus Digestive 1.19 1.1 – 1.29 1.84e-05 762 7584 all phecode
530.14 Reflux esophagitis Digestive 1.09 1.04 – 1.15 0.000438 1900 17495 all phecode
530.15 Eosinophilic esophagitis Digestive 1.06 0.915 – 1.23 0.44 221 2210 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.1 1.01 – 1.2 0.023 651 6473 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.08 1 – 1.15 0.0466 911 8971 all phecode
530.5 Disorders of esophageal motility Digestive 1.09 0.991 – 1.19 0.0783 548 5432 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.943 0.78 – 1.14 0.548 129 1265 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.14 0.899 – 1.45 0.274 82 812 all phecode
530.9 Heartburn Digestive 1.12 1.06 – 1.19 4.01e-05 1519 14928 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.1 1.04 – 1.15 0.000177 2073 20617 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.04 0.93 – 1.16 0.513 391 3883 all phecode
531.2 Gastric ulcer Digestive 1.13 1.06 – 1.2 0.000161 1201 11970 all phecode
531.3 Duodenal ulcer Digestive 1.05 0.952 – 1.16 0.324 467 4640 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.05 0.972 – 1.13 0.215 804 8018 all phecode
531.5 Gastrojejunal ulcer Digestive 1.34 1.12 – 1.6 0.0014 150 1500 all phecode
532 Dysphagia Digestive 1.11 1.07 – 1.14 1.85e-10 5585 26852 all phecode
535 Gastritis and duodenitis Digestive 1.07 1.03 – 1.12 0.000613 2799 27335 all phecode
535.1 Acute gastritis Digestive 1.14 1.07 – 1.22 2.57e-05 1178 11750 all phecode
535.2 Atrophic gastritis Digestive 0.991 0.881 – 1.11 0.876 344 3413 all phecode
535.6 Duodenitis Digestive 1.02 0.905 – 1.14 0.776 334 3337 all phecode
535.8 Other specified gastritis Digestive 0.996 0.914 – 1.08 0.921 638 6354 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.03 0.972 – 1.1 0.292 1255 12511 all phecode
536 Disorders of function of stomach Digestive 1.03 0.985 – 1.07 0.212 2911 27685 all phecode
536.3 Gastroparesis Digestive 1.07 0.985 – 1.16 0.108 706 6901 all phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.06 0.956 – 1.18 0.256 407 4059 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.01 0.962 – 1.06 0.741 2150 21094 all phecode
537 Other disorders of stomach and duodenum Digestive 1.09 1.04 – 1.13 3.1e-05 3183 30048 all phecode
537.1 Lesions of stomach and duodenum Digestive 1.14 0.974 – 1.34 0.102 173 1725 all phecode
539 Bariatric surgery Digestive 1.78 1.68 – 1.89 7.76e-84 1509 15074 all phecode
540 Appendiceal conditions Digestive 0.953 0.864 – 1.05 0.341 495 4948 all phecode
540.1 Appendicitis Digestive 0.937 0.843 – 1.04 0.228 425 4239 all phecode
540.11 Acute appendicitis Digestive 0.908 0.808 – 1.02 0.104 353 3511 all phecode
550 Abdominal hernia Digestive 1.05 1.02 – 1.08 0.00074 6768 37731 all phecode
550.1 Inguinal hernia Digestive 0.838 0.796 – 0.883 2.68e-11 1744 16488 all phecode
550.2 Diaphragmatic hernia Digestive 1.06 1.02 – 1.11 0.00342 2817 25849 all phecode
550.3 Femoral hernia Digestive 0.713 0.586 – 0.869 0.000789 131 1291 all phecode
550.4 Umbilical hernia Digestive 1.07 1 – 1.13 0.0356 1313 13110 all phecode
550.5 Ventral hernia Digestive 1.18 1.13 – 1.24 5.25e-13 2241 22163 all phecode
550.6 Incisional hernia Digestive 1.19 1.12 – 1.27 6.45e-09 1313 13111 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.07 1.01 – 1.13 0.0249 1536 15153 all phecode
555.1 Regional enteritis Digestive 1.12 1.04 – 1.2 0.00206 919 9095 all phecode
555.2 Ulcerative colitis Digestive 0.98 0.913 – 1.05 0.577 937 9315 all phecode
555.21 Ulcerative colitis (chronic) Digestive 0.912 0.831 – 1 0.0559 537 5315 all phecode
556 Ulceration of the lower GI tract Digestive 1.1 1.01 – 1.2 0.0273 632 6267 all phecode
556.1 Ulceration of intestine Digestive 1.09 0.997 – 1.2 0.0575 551 5451 all phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 0.984 0.85 – 1.14 0.834 214 2093 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.2 1.14 – 1.27 5.89e-12 1716 16490 all phecode
557.1 Celiac disease Digestive 0.944 0.849 – 1.05 0.281 421 4026 all phecode
558 Noninfectious gastroenteritis Digestive 1.07 1.03 – 1.11 0.000463 3458 26408 all phecode
559 Ileostomy status Digestive 1.03 0.965 – 1.11 0.337 957 9565 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.07 1.03 – 1.11 0.00082 3004 24851 all phecode
560.1 Paralytic ileus Digestive 1.06 1 – 1.12 0.0329 1627 15714 all phecode
560.2 Impaction of intestine Digestive 1.09 0.976 – 1.22 0.124 387 3779 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.946 0.827 – 1.08 0.417 266 2647 all phecode
560.4 Other intestinal obstruction Digestive 1.06 1.01 – 1.12 0.0254 1651 16170 all phecode
561 Symptoms involving digestive system Digestive 1.02 0.977 – 1.06 0.374 2608 21766 all phecode
562 Diverticulosis and diverticulitis Digestive 1.04 1 – 1.07 0.0225 6295 23431 all phecode
562.1 Diverticulosis Digestive 1.03 1 – 1.07 0.0287 6246 23383 all phecode
562.2 Diverticulitis Digestive 1.05 0.992 – 1.11 0.0962 1611 15162 all phecode
564 Functional digestive disorders Digestive 1.06 1.04 – 1.09 6.47e-07 11411 28676 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.04 0.998 – 1.08 0.0663 3457 22266 all phecode
564.9 Personal history of diseases of digestive system Digestive 1.09 1.04 – 1.13 3.9e-05 3074 25861 all phecode
565 Anal and rectal conditions Digestive 1 0.965 – 1.04 0.898 3355 30757 all phecode
565.1 Anal and rectal polyp Digestive 1.01 0.948 – 1.07 0.82 1305 12649 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.12 1.06 – 1.19 0.000105 1364 13616 all phecode
568 Other disorders of peritoneum Digestive 1.14 1.08 – 1.2 6.51e-07 1705 17038 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.17 1.11 – 1.25 2.42e-07 1247 12468 all phecode
569 Other disorders of intestine Digestive 1.06 1.03 – 1.09 7.18e-06 8079 35231 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.06 0.941 – 1.2 0.336 326 3260 all phecode
569.2 Gastrointestinal complications Digestive 1.17 1.1 – 1.24 2.08e-07 1395 13933 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.14 1.1 – 1.17 1.76e-14 4610 32562 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.14 1.1 – 1.18 2.99e-14 4342 32234 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.12 1.05 – 1.2 0.00107 1018 10095 all phecode
571.6 Primary biliary cirrhosis Digestive 1.04 0.892 – 1.22 0.586 179 1790 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.1 1.02 – 1.18 0.00854 950 9498 all phecode
571.81 Portal hypertension Digestive 1.08 0.992 – 1.19 0.0753 573 5730 all phecode
572 Ascites (non malignant) Digestive 1.07 1.02 – 1.12 0.00387 2278 22675 all phecode
573 Other disorders of liver Digestive 1.08 1.05 – 1.11 6.77e-07 5599 33620 all phecode
573.1 Chronic passive congestion of liver Digestive 1.35 1.12 – 1.63 0.00143 136 1359 all phecode
573.2 Liver replaced by transplant Digestive 1.07 0.943 – 1.22 0.286 292 2920 all phecode
573.3 Hepatomegaly Digestive 1.2 1.08 – 1.32 0.000409 470 4700 all phecode
573.4 Acute and subacute necrosis of liver Digestive 0.999 0.884 – 1.13 0.993 316 3149 all phecode
573.5 Jaundice (not of newborn) Digestive 1.07 0.995 – 1.14 0.0677 958 9496 all phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.04 1 – 1.09 0.0454 2756 26470 all phecode
573.7 Abnormal results of function study of liver Digestive 1.04 0.999 – 1.08 0.0552 3018 27774 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.03 1 – 1.07 0.0414 4679 33866 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.13 1.09 – 1.17 5.4e-10 3177 30809 all phecode
574.1 Cholelithiasis Digestive 1.13 1.09 – 1.18 2.66e-09 2924 28874 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.22 1.09 – 1.37 0.000866 342 3412 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.09 0.991 – 1.19 0.078 553 5501 all phecode
574.2 Calculus of bile duct Digestive 1.05 0.976 – 1.13 0.183 852 8503 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.16 1.08 – 1.25 8.93e-05 822 8181 all phecode
575 Other biliary tract disease Digestive 1.05 1 – 1.1 0.0393 2266 22555 all phecode
575.1 Cholangitis Digestive 1.02 0.906 – 1.14 0.791 354 3530 all phecode
575.2 Obstruction of bile duct Digestive 1.15 1.05 – 1.26 0.00166 621 6201 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.945 0.815 – 1.1 0.459 207 2063 all phecode
575.7 Other disorders of gallbladder Digestive 1.02 0.953 – 1.1 0.524 939 9382 all phecode
575.8 Other disorders of biliary tract Digestive 1.07 1 – 1.14 0.0427 1154 11523 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.01 0.881 – 1.15 0.914 260 2600 all phecode
577 Diseases of pancreas Digestive 1.07 1.02 – 1.12 0.00654 2225 22106 all phecode
577.1 Acute pancreatitis Digestive 1.12 1.06 – 1.19 0.000252 1212 12110 all phecode
577.2 Chronic pancreatitis Digestive 1.17 1.06 – 1.29 0.00213 495 4950 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.01 0.92 – 1.11 0.834 570 5601 all phecode
578 Gastrointestinal hemorrhage Digestive 1.04 1.01 – 1.08 0.0108 4554 37045 all phecode
578.1 Hematemesis Digestive 1.13 1.02 – 1.24 0.0169 485 4842 all phecode
578.2 Blood in stool Digestive 1.07 1.03 – 1.11 0.00171 2743 26554 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.02 0.973 – 1.07 0.419 2210 21750 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.07 1.02 – 1.13 0.0113 1562 15345 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.1 1.07 – 1.14 8.17e-09 4431 34209 all phecode
579.2 Splenomegaly Digestive 1.16 1.07 – 1.26 0.000192 730 7262 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.04 0.982 – 1.1 0.179 1410 13877 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.22 1.16 – 1.29 1.91e-14 1881 15516 all phecode
580.1 Glomerulonephritis Genitourinary 1.19 1.06 – 1.32 0.00222 401 3992 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.13 0.942 – 1.35 0.192 146 1440 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.4 1.15 – 1.72 0.00107 114 1128 all phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.04 0.79 – 1.36 0.793 61 600 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.26 1.1 – 1.43 0.000648 277 2760 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.16 1 – 1.34 0.0454 221 2193 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.24 1.17 – 1.31 6.6e-13 1502 11930 all phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.31 1.22 – 1.41 1.3e-13 992 7228 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.14 1.05 – 1.24 0.00153 683 6612 all phecode
580.4 Renal sclerosis, NOS Genitourinary 1.18 1.05 – 1.33 0.00442 340 3400 all phecode
585 Renal failure Genitourinary 1.18 1.15 – 1.21 9.78e-32 7470 32340 all phecode
585.1 Acute renal failure Genitourinary 1.17 1.13 – 1.22 7.17e-20 4265 27230 all phecode
585.2 Renal failure NOS Genitourinary 1.2 1.12 – 1.3 1.34e-06 832 8162 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.2 1.17 – 1.24 2.61e-31 5580 29470 all phecode
585.31 Renal dialysis Genitourinary 1.2 1.11 – 1.3 8.79e-06 747 7423 all phecode
585.32 End stage renal disease Genitourinary 1.27 1.19 – 1.36 6.35e-12 1007 9783 all phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.22 1.17 – 1.27 1.54e-21 3209 21312 all phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.25 1.17 – 1.34 3.64e-10 977 9190 all phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.21 1.13 – 1.28 4.27e-09 1227 11191 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.12 1.09 – 1.15 1.02e-15 7628 34189 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.13 1.01 – 1.27 0.0314 349 3480 all phecode
586.11 Small kidney Genitourinary 1.16 1.01 – 1.35 0.0413 210 2093 all phecode
586.12 Vesicoureteral reflux Genitourinary 1.09 0.905 – 1.31 0.365 136 1360 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.05 0.989 – 1.11 0.111 1381 12912 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.16 0.998 – 1.36 0.0537 187 1862 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.04 0.986 – 1.09 0.153 1821 17115 all phecode
587 Kidney replaced by transpant Genitourinary 1.13 1.05 – 1.22 0.0015 819 8134 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.23 1.14 – 1.31 8.2e-09 976 9389 all phecode
588.1 Renal osteodystrophy Genitourinary 1.13 0.995 – 1.29 0.0594 290 2900 all phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.23 1.14 – 1.33 3.41e-07 755 7275 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.15 1.08 – 1.23 5.48e-05 1007 9834 all phecode
590 Pyelonephritis Genitourinary 1.14 1.08 – 1.21 4.07e-06 1461 14350 all phecode
591 Urinary tract infection Genitourinary 1.03 1 – 1.05 0.0331 9873 32513 all phecode
592 Cystitis and urethritis Genitourinary 1.01 0.965 – 1.05 0.807 3038 24207 all phecode
592.1 Cystitis Genitourinary 1.01 0.966 – 1.05 0.733 2880 23279 all phecode
592.11 Acute cystitis Genitourinary 1 0.953 – 1.06 0.878 1783 16452 all phecode
592.12 Chronic cystitis Genitourinary 0.972 0.845 – 1.12 0.687 239 2343 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.953 0.858 – 1.06 0.368 431 4310 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.01 0.868 – 1.17 0.926 210 2093 all phecode
593 Hematuria Genitourinary 1.04 1.01 – 1.07 0.0164 4859 32063 all phecode
593.1 Gross hematuria Genitourinary 1.07 1.01 – 1.13 0.0177 1585 14824 all phecode
593.2 Microscopic hematuria Genitourinary 1.02 0.953 – 1.09 0.571 1049 10301 all phecode
594 Urinary calculus Genitourinary 1.07 1.04 – 1.1 1.09e-06 6707 38209 all phecode
594.1 Calculus of kidney Genitourinary 1.07 1.04 – 1.1 1.24e-06 6273 38051 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.11 0.995 – 1.24 0.061 366 3638 all phecode
594.3 Calculus of ureter Genitourinary 1.05 0.992 – 1.12 0.0881 1361 13561 all phecode
594.8 Renal colic Genitourinary 1.1 0.985 – 1.24 0.0883 356 3560 all phecode
595 Hydronephrosis Genitourinary 1.07 1.01 – 1.13 0.0121 1670 16658 all phecode
596 Other disorders of bladder Genitourinary 1 0.965 – 1.04 0.864 3074 28020 all phecode
596.1 Bladder neck obstruction Genitourinary 0.986 0.885 – 1.1 0.804 400 3942 all phecode
596.5 Functional disorders of bladder Genitourinary 0.992 0.941 – 1.05 0.759 1719 17049 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.965 0.907 – 1.03 0.257 1211 11998 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.942 0.867 – 1.02 0.16 661 6537 all phecode
597.2 Urinary complications NEC Genitourinary 1.02 0.953 – 1.09 0.581 1049 10479 all phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.03 0.883 – 1.21 0.674 189 1873 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.02 0.841 – 1.23 0.856 138 1356 all phecode
598.4 Other cells and casts in urine Genitourinary 1.02 0.829 – 1.24 0.881 122 1192 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.987 – 1.03 0.422 14168 30681 all phecode
599.1 Urinary obstruction Genitourinary 0.898 0.828 – 0.973 0.00847 728 6861 all phecode
599.2 Retention of urine Genitourinary 0.998 0.967 – 1.03 0.92 5034 28305 all phecode
599.3 Dysuria Genitourinary 0.996 0.963 – 1.03 0.831 4397 27849 all phecode
599.4 Urinary incontinence Genitourinary 1.03 0.999 – 1.06 0.0567 5599 26960 all phecode
599.5 Frequency of urination and polyuria Genitourinary 0.982 0.952 – 1.01 0.246 5498 28723 all phecode
599.6 Oliguria and anuria Genitourinary 1.14 1.04 – 1.25 0.00401 599 5902 all phecode
599.7 Urethral discharge Genitourinary 1.09 0.902 – 1.33 0.361 118 1175 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.01 0.976 – 1.04 0.666 5446 27963 all phecode
599.9 Other abnormality of urination Genitourinary 0.968 0.93 – 1.01 0.116 3041 24877 all phecode
600 Hyperplasia of prostate Genitourinary 0.953 0.916 – 0.992 0.0195 4063 11364 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.983 0.92 – 1.05 0.618 1044 9665 all phecode
601.1 Prostatitis Genitourinary 0.859 0.778 – 0.949 0.00264 477 4596 all phecode
601.11 Acute prostatitis Genitourinary 0.991 0.814 – 1.21 0.928 124 1200 all phecode
601.12 Chronic prostatitis Genitourinary 0.916 0.733 – 1.14 0.44 95 943 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.08 0.968 – 1.2 0.171 389 3822 all phecode
601.4 Balanoposthitis Genitourinary 1.01 0.833 – 1.22 0.927 127 1224 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.2 1.01 – 1.42 0.0365 161 1591 all phecode
602 Other disorders of prostate Genitourinary 0.889 0.791 – 0.999 0.0476 361 3399 all phecode
602.3 Dysplasia of prostate Genitourinary 0.979 0.765 – 1.25 0.865 77 730 all phecode
603 Other disorders of testis Genitourinary 1.01 0.911 – 1.12 0.87 440 4354 all phecode
603.1 Hydrocele Genitourinary 1.01 0.892 – 1.14 0.909 293 2882 all phecode
603.2 Spermatocele Genitourinary 0.915 0.773 – 1.08 0.303 156 1539 all phecode
604 Disorders of penis Genitourinary 0.965 0.889 – 1.05 0.386 685 6748 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.29 1.09 – 1.52 0.00341 155 1540 all phecode
604.3 Peyronie's disease Genitourinary 0.851 0.736 – 0.984 0.0296 215 2132 all phecode
605 Erectile dysfunction [ED] Genitourinary 0.968 0.931 – 1.01 0.102 3776 12700 all phecode
608 Other disorders of male genital organs Genitourinary 0.989 0.938 – 1.04 0.696 1645 13758 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.902 0.813 – 1 0.0518 424 4196 all phecode
609.1 Infertility, male Genitourinary 0.943 0.835 – 1.07 0.346 302 2992 all phecode
609.11 Azoospermia and oligospermia Genitourinary 1.15 0.93 – 1.43 0.191 95 950 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.782 0.657 – 0.931 0.00573 154 1519 all phecode
610 Benign mammary dysplasias Genitourinary 0.918 0.883 – 0.954 1.35e-05 3683 16548 all phecode
610.1 Cystic mastopathy Genitourinary 0.932 0.882 – 0.984 0.0116 1633 14191 all phecode
610.2 Fibroadenosis of breast Genitourinary 0.821 0.623 – 1.08 0.161 60 600 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.899 0.861 – 0.939 1.26e-06 2837 16430 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.927 0.871 – 0.987 0.0176 1269 12191 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.911 0.882 – 0.94 5.83e-09 6067 18690 all phecode
611.1 Abnormal mammogram Genitourinary 0.893 0.862 – 0.924 1.23e-10 4980 16120 all phecode
611.11 Mammographic microcalcification Genitourinary 0.823 0.77 – 0.88 1.01e-08 1122 10394 all phecode
611.3 Lump or mass in breast Genitourinary 0.899 0.865 – 0.935 6.61e-08 3549 18572 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.962 0.899 – 1.03 0.264 1051 10425 all phecode
612.1 Galactorrhea Genitourinary 0.931 0.778 – 1.11 0.436 139 1390 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.02 0.947 – 1.11 0.561 800 7962 all phecode
612.3 Congenital anomalies of breast Genitourinary 0.616 0.479 – 0.793 0.000164 83 810 all phecode
613 Other nonmalignant breast conditions Genitourinary 0.966 0.931 – 1 0.0605 3897 22072 all phecode
613.1 Inflammatory disease of breast Genitourinary 0.958 0.877 – 1.05 0.344 593 5874 all phecode
613.5 Mastodynia Genitourinary 0.982 0.93 – 1.04 0.503 1675 16203 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.919 0.853 – 0.989 0.0244 883 8754 all phecode
613.8 Other specified disorders of breast Genitourinary 0.877 0.815 – 0.943 0.000383 932 9248 all phecode
613.9 Breast disorder NOS Genitourinary 0.941 0.888 – 0.997 0.0389 1465 14174 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.999 0.962 – 1.04 0.965 3715 19647 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.03 0.919 – 1.16 0.573 337 3370 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.03 0.931 – 1.14 0.587 478 4773 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.19 0.954 – 1.5 0.122 94 933 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.899 0.766 – 1.05 0.19 186 1842 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.985 0.858 – 1.13 0.83 246 2460 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.03 0.867 – 1.22 0.734 165 1639 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.994 0.955 – 1.03 0.779 3180 19539 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.04 0.911 – 1.19 0.544 264 2640 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.98 0.939 – 1.02 0.351 2732 18924 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.12 0.927 – 1.36 0.239 132 1311 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.13 0.972 – 1.3 0.113 225 2244 all phecode
615 Endometriosis Genitourinary 1 0.951 – 1.06 0.871 1585 14666 all phecode
618 Genital prolapse Genitourinary 0.98 0.933 – 1.03 0.406 2079 17915 all phecode
618.1 Prolapse of vaginal walls Genitourinary 0.939 0.885 – 0.996 0.0357 1408 13456 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.947 0.861 – 1.04 0.265 542 5390 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.941 0.829 – 1.07 0.347 317 3162 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.06 0.958 – 1.18 0.252 441 4394 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.996 0.965 – 1.03 0.815 5728 18687 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.03 0.963 – 1.09 0.434 1233 12082 all phecode
619.2 Disorders of uterus, NEC Genitourinary 0.957 0.875 – 1.05 0.343 591 5897 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.979 0.887 – 1.08 0.679 483 4823 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.992 0.949 – 1.04 0.737 2525 18404 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.05 0.981 – 1.11 0.173 1189 11717 all phecode
620 Dysplasia of female genital organs Genitourinary 1.08 0.965 – 1.2 0.19 395 3950 all phecode
620.1 Dysplasia of cervix Genitourinary 1.04 0.883 – 1.22 0.664 178 1780 all phecode
621 Endometrial hyperplasia Genitourinary 1.09 0.98 – 1.21 0.113 437 4370 all phecode
622 Polyp of female genital organs Genitourinary 0.942 0.889 – 0.998 0.0416 1449 14264 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.972 0.91 – 1.04 0.393 1132 11189 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.861 0.774 – 0.957 0.00543 445 4444 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.04 0.966 – 1.13 0.279 824 8165 all phecode
624 Symptoms involving female genital tract Genitourinary 0.975 0.918 – 1.03 0.403 1348 12518 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.88 0.759 – 1.02 0.0881 216 2155 all phecode
624.2 Atrophy of female genital tract Genitourinary 1.12 0.841 – 1.49 0.442 64 615 all phecode
624.9 stress incontinence, female Genitourinary 1.03 0.976 – 1.08 0.316 1935 15408 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.985 0.954 – 1.02 0.371 5653 17303 all phecode
625.1 Dyspareunia Genitourinary 0.933 0.877 – 0.992 0.0275 1267 12474 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1 0.968 – 1.03 0.986 5940 15585 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.997 0.961 – 1.03 0.858 4315 14604 all phecode
626.11 Absent or infrequent menstruation Genitourinary 1.03 0.959 – 1.1 0.455 1062 8531 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.01 0.964 – 1.06 0.623 2097 11991 all phecode
626.13 Irregular menstrual cycle Genitourinary 1.01 0.958 – 1.06 0.755 1957 12265 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.965 0.899 – 1.04 0.318 970 8996 all phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.989 0.887 – 1.1 0.848 394 3789 all phecode
626.2 Dysmenorrhea Genitourinary 1.05 0.986 – 1.11 0.138 1373 9857 all phecode
626.4 Premenstrual tension syndromes Genitourinary 1.01 0.893 – 1.14 0.913 336 3308 all phecode
626.8 Infertility, female Genitourinary 0.967 0.895 – 1.04 0.391 817 6741 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.938 0.905 – 0.972 0.000473 4560 14557 all phecode
627.1 Postmenopausal bleeding Genitourinary 0.962 0.901 – 1.03 0.247 1146 10338 all phecode
627.2 Symptomatic menopause Genitourinary 0.922 0.884 – 0.962 2e-04 3017 13763 all phecode
627.21 Symptomatic artificial menopause Genitourinary 0.865 0.723 – 1.03 0.11 152 1514 all phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.751 0.667 – 0.845 2.2e-06 356 3513 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.894 0.833 – 0.96 0.0019 997 9484 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.946 0.843 – 1.06 0.337 361 3580 all phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.883 0.78 – 1 0.0492 309 3082 all phecode
628 Ovarian cyst Genitourinary 1.01 0.961 – 1.06 0.673 1945 13838 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.993 0.921 – 1.07 0.848 826 8047 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.947 0.831 – 1.08 0.416 273 2715 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.01 0.824 – 1.24 0.928 117 1170 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.885 0.808 – 0.97 0.00927 563 5309 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.877 0.782 – 0.983 0.0237 370 3629 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.876 0.77 – 0.995 0.0417 288 2850 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.95 0.888 – 1.02 0.135 1080 7870 all phecode
636.1 Threatened premature labor Pregnancy Complications 0.955 0.854 – 1.07 0.413 380 3799 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.956 0.84 – 1.09 0.489 288 2868 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.984 0.888 – 1.09 0.754 441 4365 all phecode
636.8 Cervical incompetence Pregnancy Complications 1.1 0.861 – 1.4 0.455 77 770 all phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.1 0.877 – 1.39 0.397 85 850 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.04 0.947 – 1.13 0.443 585 5725 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.03 0.908 – 1.16 0.673 302 3013 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.09 0.949 – 1.25 0.229 252 2506 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.06 0.878 – 1.29 0.525 119 1190 all phecode
644 Anemia during pregnancy Pregnancy Complications 1.04 0.896 – 1.2 0.638 224 2224 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.02 0.949 – 1.1 0.545 855 6531 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.969 0.838 – 1.12 0.664 211 2093 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1 0.87 – 1.16 0.958 222 2213 all phecode
647.3 Major puerperal infection Pregnancy Complications 1.15 0.885 – 1.5 0.292 65 650 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.988 0.928 – 1.05 0.707 1275 8010 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.04 0.958 – 1.14 0.331 649 5687 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.981 0.897 – 1.07 0.668 587 5463 all phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.992 0.852 – 1.15 0.915 207 2055 all phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 0.88 0.755 – 1.03 0.102 204 2040 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.94 0.889 – 0.994 0.0299 1624 10064 all phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 0.959 0.878 – 1.05 0.351 616 5533 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.01 0.937 – 1.08 0.826 898 7014 all phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 1.1 0.854 – 1.42 0.453 66 660 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.933 0.867 – 1 0.0669 887 6802 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.07 0.928 – 1.23 0.362 236 2351 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.11 0.935 – 1.32 0.234 158 1580 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.834 0.71 – 0.978 0.0258 184 1814 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.14 1.11 – 1.18 5.28e-21 6500 38394 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.03 0.973 – 1.1 0.281 1256 11462 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.14 1.06 – 1.22 0.000307 1007 9981 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.18 1.12 – 1.23 1.44e-11 2123 19952 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.19 1.14 – 1.25 1.18e-13 2252 20944 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.19 1.13 – 1.25 4.8e-11 1820 16893 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.21 1.14 – 1.28 1.58e-11 1572 15588 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.1 1.05 – 1.15 6.52e-05 2257 21750 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.14 1.04 – 1.25 0.00389 558 5504 all phecode
686.2 Impetigo Dermatologic 1.09 0.978 – 1.22 0.119 414 4117 all phecode
686.3 Pilonidal cyst Dermatologic 1.1 0.936 – 1.3 0.24 160 1594 all phecode
686.4 Pyogenic granuloma Dermatologic 1.02 0.861 – 1.21 0.827 158 1570 all phecode
686.5 Pyoderma Dermatologic 1.13 0.867 – 1.49 0.358 63 630 all phecode
687 Symptoms affecting skin Dermatologic 0.967 0.917 – 1.02 0.217 1690 16343 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.996 0.969 – 1.02 0.788 7007 34623 all phecode
687.3 Changes in skin texture Dermatologic 1.08 0.976 – 1.2 0.133 415 4121 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.05 1.02 – 1.08 0.000821 6375 34216 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.936 0.913 – 0.959 8.72e-08 9311 37335 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.898 0.87 – 0.927 2.43e-11 5184 31581 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.898 0.87 – 0.927 2.37e-11 5174 31553 all phecode
691 Congenital anomalies of skin Dermatologic 0.991 0.903 – 1.09 0.847 541 5337 all phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 1.06 0.81 – 1.38 0.675 62 613 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.909 0.864 – 0.956 0.000217 1861 17936 all phecode
694.1 Vitiligo Dermatologic 1.07 0.889 – 1.29 0.471 137 1347 all phecode
694.2 Other dyschromia Dermatologic 0.902 0.855 – 0.951 0.000148 1674 16183 all phecode
694.3 Vascular disorders of skin Dermatologic 1.01 0.787 – 1.29 0.959 82 819 all phecode
695 Erythematous conditions Dermatologic 1.02 0.984 – 1.05 0.307 4120 30247 all phecode
695.1 Toxic erythema Dermatologic 1.18 0.915 – 1.53 0.199 70 688 all phecode
695.2 Bullous dermatoses Dermatologic 0.956 0.754 – 1.21 0.71 85 805 all phecode
695.3 Rosacea Dermatologic 0.917 0.871 – 0.965 0.000958 1816 17663 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.04 0.952 – 1.13 0.412 672 6686 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.1 0.961 – 1.27 0.164 247 2437 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.02 0.937 – 1.11 0.637 637 6337 all phecode
695.7 Prurigo and Lichen Dermatologic 0.973 0.891 – 1.06 0.544 605 5986 all phecode
695.8 Other specified erythematous conditions Dermatologic 1.15 1.06 – 1.24 0.000472 812 7980 all phecode
695.81 Erythema nodosum Dermatologic 0.961 0.72 – 1.28 0.79 55 550 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.16 1.07 – 1.26 0.000393 679 6756 all phecode
696 Psoriasis and related disorders Dermatologic 1.03 0.977 – 1.1 0.247 1401 13832 all phecode
696.3 Pityriasis Dermatologic 0.855 0.685 – 1.07 0.166 92 904 all phecode
696.4 Psoriasis Dermatologic 1.06 0.998 – 1.13 0.057 1311 12976 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.05 0.986 – 1.12 0.132 1200 11867 all phecode
696.42 Psoriatic arthropathy Dermatologic 1 0.878 – 1.14 0.999 282 2810 all phecode
697 Sarcoidosis Dermatologic 1.07 0.957 – 1.21 0.225 333 3330 all phecode
698 Pruritus and related conditions Dermatologic 0.992 0.947 – 1.04 0.719 2254 21889 all phecode
700 Corns and callosities Dermatologic 1.05 0.992 – 1.12 0.0873 1373 10894 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1 0.976 – 1.03 0.86 7651 38050 all phecode
701.1 Keratoderma, acquired Dermatologic 1.02 0.928 – 1.11 0.723 567 5524 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.922 0.88 – 0.966 0.000599 2184 21550 all phecode
701.3 Circumscribed scleroderma Dermatologic 0.955 0.871 – 1.05 0.333 571 5660 all phecode
701.4 Keloid scar Dermatologic 0.993 0.907 – 1.09 0.88 578 5716 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.06 0.949 – 1.17 0.32 400 3982 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.881 0.856 – 0.907 3.63e-18 6956 29525 all phecode
702.1 Actinic keratosis Dermatologic 0.853 0.823 – 0.884 1.02e-18 4171 26529 all phecode
702.2 Seborrheic keratosis Dermatologic 0.872 0.845 – 0.9 5.6e-18 5480 31552 all phecode
702.4 Degenerative skin disorders Dermatologic 1.11 0.883 – 1.4 0.366 86 832 all phecode
703 Diseases of nail, NOS Dermatologic 1.04 0.982 – 1.09 0.199 1650 14562 all phecode
703.1 Ingrowing nail Dermatologic 1.04 0.972 – 1.12 0.237 920 8597 all phecode
704 Diseases of hair and hair follicles Dermatologic 0.961 0.925 – 1 0.049 3118 29542 all phecode
704.1 Alopecia Dermatologic 0.947 0.893 – 1 0.0668 1408 13871 all phecode
704.11 Alopecia Areata Dermatologic 0.834 0.657 – 1.06 0.136 82 811 all phecode
704.12 Telogen effluvium Dermatologic 0.833 0.633 – 1.09 0.19 63 615 all phecode
704.2 Hirsutism Dermatologic 1.39 1.23 – 1.57 2.08e-07 299 2946 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.961 0.913 – 1.01 0.136 1752 17189 all phecode
705 Disorders of sweat glands Dermatologic 1.22 1.12 – 1.34 7.73e-06 603 6012 all phecode
705.1 Dyshidrosis Dermatologic 1.07 0.898 – 1.28 0.442 154 1540 all phecode
705.3 Hidradenitis Dermatologic 1.39 1.21 – 1.6 3.33e-06 245 2440 all phecode
705.8 Hyperhidrosis Dermatologic 1.03 0.966 – 1.1 0.349 1112 10986 all phecode
706 Diseases of sebaceous glands Dermatologic 0.93 0.903 – 0.957 8.45e-07 5995 39748 all phecode
706.1 Acne Dermatologic 0.863 0.827 – 0.901 2.06e-11 2594 22570 all phecode
706.2 Sebaceous cyst Dermatologic 0.949 0.91 – 0.989 0.0121 2814 26819 all phecode
706.3 Seborrhea Dermatologic 0.829 0.632 – 1.09 0.178 59 582 all phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.975 0.924 – 1.03 0.354 1684 15289 all phecode
707 Chronic ulcer of skin Dermatologic 1.17 1.12 – 1.21 1.98e-13 2871 26816 all phecode
707.1 Decubitus ulcer Dermatologic 1.13 1.05 – 1.22 0.00132 825 8119 all phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.27 1.19 – 1.35 7.5e-13 1108 9992 all phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1.15 1.09 – 1.21 3.6e-07 1641 16172 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.992 0.937 – 1.05 0.794 1477 14427 all phecode
709.2 Sicca syndrome Dermatologic 1.03 0.931 – 1.13 0.597 505 4986 all phecode
709.3 Systemic sclerosis Dermatologic 0.83 0.719 – 0.958 0.0107 224 2209 all phecode
709.5 Dermatomyositis Dermatologic 1.1 0.882 – 1.36 0.41 92 892 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.993 0.783 – 1.26 0.953 90 892 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.01 0.936 – 1.08 0.856 917 9089 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.19 1.12 – 1.27 2.29e-08 1254 12103 all phecode
710.1 Osteomyelitis Musculoskeletal 1.19 1.12 – 1.27 3.75e-08 1203 11636 all phecode
710.11 Acute osteomyelitis Musculoskeletal 1.34 1.22 – 1.46 5.33e-10 590 5708 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.24 1.12 – 1.36 1.19e-05 531 5163 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.21 1.13 – 1.29 9.07e-09 1153 11149 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.07 0.957 – 1.19 0.243 410 4099 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.17 1.03 – 1.33 0.0174 290 2900 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.31 1.11 – 1.55 0.00168 178 1776 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.19 1.05 – 1.34 0.00598 314 3028 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.27 1.08 – 1.49 0.00309 194 1824 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.14 1.09 – 1.2 8.2e-08 2086 18159 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.18 1.12 – 1.24 3.93e-09 1670 15087 all phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.04 0.816 – 1.33 0.733 77 767 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.13 1.06 – 1.2 0.000118 1209 11967 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.18 1.03 – 1.34 0.0167 262 2611 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.2 1.04 – 1.38 0.0137 219 2182 all phecode
716 Other arthropathies Musculoskeletal 1.12 1.1 – 1.15 6.98e-24 13482 31305 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.08 0.924 – 1.26 0.329 192 1920 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.949 0.786 – 1.15 0.583 131 1293 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.12 1.1 – 1.15 5.97e-24 13410 31294 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.974 0.85 – 1.12 0.708 261 2565 all phecode
720 Spinal stenosis Musculoskeletal 1.11 1.07 – 1.15 4.43e-09 3958 28539 all phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1.13 1.08 – 1.18 1.2e-08 2872 23656 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1.06 1.03 – 1.1 7.79e-05 5509 32391 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.06 1.02 – 1.09 0.000547 5153 31896 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.11 1.03 – 1.19 0.00714 867 8629 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.26 1.1 – 1.44 0.000663 262 2600 all phecode
722 Intervertebral disc disorders Musculoskeletal 1.09 1.06 – 1.13 5.43e-10 6284 34317 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.08 1.04 – 1.12 2.26e-05 3591 31411 all phecode
722.3 Schmorl's nodes Musculoskeletal 1.15 0.944 – 1.4 0.164 126 1248 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.08 1.05 – 1.12 9.76e-06 3957 30744 all phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.11 1.01 – 1.22 0.0354 515 5140 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.1 0.988 – 1.23 0.0821 397 3968 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.08 1.03 – 1.13 0.00233 1932 19288 all phecode
723 Other disorders of cervical region Musculoskeletal 1.02 0.946 – 1.09 0.671 952 9495 all phecode
723.1 Torticollis Musculoskeletal 0.986 0.863 – 1.13 0.842 254 2522 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.06 1.02 – 1.1 0.00127 4130 31954 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.06 1.01 – 1.11 0.0112 2307 21902 all phecode
724.2 Disorders of coccyx Musculoskeletal 0.968 0.87 – 1.08 0.542 426 4215 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.12 1.04 – 1.21 0.00173 931 9295 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.09 1.02 – 1.15 0.00568 1412 14087 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.982 0.959 – 1.01 0.146 9917 30176 all phecode
726.1 Enthesopathy Musculoskeletal 0.977 0.951 – 1 0.0903 7507 30106 all phecode
726.2 Synoviopathy Musculoskeletal 1 0.936 – 1.07 0.948 1015 9987 all phecode
726.3 Bursitis Musculoskeletal 0.974 0.925 – 1.03 0.314 1829 16722 all phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 1.01 0.946 – 1.07 0.824 1193 11485 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1 0.974 – 1.03 0.972 7425 30105 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.02 0.977 – 1.06 0.402 3092 24998 all phecode
727.2 Bursitis disorders Musculoskeletal 0.994 0.891 – 1.11 0.908 419 4112 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.973 0.918 – 1.03 0.359 1400 13621 all phecode
727.5 Rupture of synovium Musculoskeletal 1.17 1.06 – 1.3 0.00182 480 4672 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.979 0.937 – 1.02 0.357 2461 21948 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.995 0.91 – 1.09 0.908 591 5893 all phecode
727.8 Plica syndrome Musculoskeletal 0.854 0.71 – 1.03 0.0946 130 1264 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.03 0.995 – 1.06 0.102 4546 29473 all phecode
728.1 Muscular calcification and ossification Musculoskeletal 0.996 0.79 – 1.26 0.972 85 843 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.911 0.804 – 1.03 0.14 297 2949 all phecode
728.7 Fasciitis Musculoskeletal 0.99 0.95 – 1.03 0.64 2814 23463 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.807 0.725 – 0.898 8.25e-05 419 4138 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.13 1.09 – 1.17 1.5e-10 3642 27471 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.05 0.822 – 1.35 0.688 74 726 all phecode
729.3 Panniculitis Musculoskeletal 1.26 1.03 – 1.54 0.0223 119 1174 all phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 0.937 0.724 – 1.21 0.618 67 664 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.18 1.02 – 1.36 0.0303 210 2091 all phecode
732 Osteochondropathies Musculoskeletal 1.1 0.985 – 1.23 0.088 361 3604 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.23 1.05 – 1.43 0.0102 198 1969 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.964 0.767 – 1.21 0.756 90 882 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.919 0.888 – 0.951 1.17e-06 4543 26941 all phecode
733.2 Cyst of bone Musculoskeletal 0.937 0.801 – 1.1 0.411 190 1900 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.966 0.879 – 1.06 0.481 518 5160 all phecode
733.6 Costochondritis Musculoskeletal 0.954 0.849 – 1.07 0.425 357 3562 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.06 0.98 – 1.14 0.151 822 8205 all phecode
733.9 Chondromalacia Musculoskeletal 0.978 0.787 – 1.22 0.841 96 960 all phecode
735 Acquired foot deformities Musculoskeletal 0.972 0.936 – 1.01 0.142 3417 29622 all phecode
735.1 Flat foot Musculoskeletal 0.984 0.902 – 1.07 0.71 620 6092 all phecode
735.2 Acquired toe deformities Musculoskeletal 0.975 0.917 – 1.04 0.412 1323 11983 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.99 0.915 – 1.07 0.792 825 7494 all phecode
735.23 Hallux rigidus Musculoskeletal 0.965 0.867 – 1.08 0.523 405 4005 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.931 0.879 – 0.985 0.0136 1470 14295 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.995 0.955 – 1.04 0.817 2763 26555 all phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.937 0.759 – 1.16 0.541 104 1033 all phecode
736.2 Acquired deformities of finger Musculoskeletal 0.877 0.757 – 1.02 0.0826 215 2142 all phecode
736.3 Acquired deformities of hip Musculoskeletal 1.03 0.774 – 1.36 0.853 60 590 all phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 1.01 0.894 – 1.13 0.932 325 3247 all phecode
736.5 Acquired deformities of knee Musculoskeletal 0.97 0.85 – 1.11 0.654 246 2460 all phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.999 0.89 – 1.12 0.99 339 3365 all phecode
737 Curvature of spine Musculoskeletal 0.945 0.895 – 0.999 0.0452 1566 15543 all phecode
737.1 Kyphosis (acquired) Musculoskeletal 0.989 0.895 – 1.09 0.821 479 4748 all phecode
737.2 Lordosis (acquired) Musculoskeletal 1.2 0.934 – 1.55 0.152 70 700 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.935 0.878 – 0.995 0.0353 1203 11982 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.01 0.967 – 1.06 0.63 2443 24187 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.12 1.05 – 1.2 0.00116 1057 10542 all phecode
739 Contracture of joint Musculoskeletal 0.96 0.879 – 1.05 0.366 621 6207 all phecode
740 Osteoarthrosis Musculoskeletal 1.13 1.11 – 1.16 8.43e-31 16169 30268 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.1 1.06 – 1.13 6.31e-10 7005 27422 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.09 1.06 – 1.12 5.65e-08 6176 26155 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.09 1 – 1.18 0.0475 713 7116 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.06 1 – 1.12 0.0384 1609 12092 all phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 1.1 0.98 – 1.23 0.107 373 3586 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.14 1.12 – 1.17 9.29e-33 15497 30141 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.01 0.987 – 1.04 0.339 8555 35884 all phecode
741.1 Ankylosis of joint Musculoskeletal 0.939 0.817 – 1.08 0.37 245 2445 all phecode
741.2 Stiffness of joint Musculoskeletal 0.943 0.887 – 1 0.0594 1268 12594 all phecode
741.3 Difficulty in walking Musculoskeletal 1.08 1.03 – 1.12 0.00103 2558 23116 all phecode
741.4 Joint effusions Musculoskeletal 1 0.96 – 1.05 0.885 2493 24199 all phecode
741.5 Hemarthrosis Musculoskeletal 0.977 0.783 – 1.22 0.839 94 937 all phecode
741.6 Villonodular synovitis Musculoskeletal 0.804 0.615 – 1.05 0.11 68 666 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.993 0.96 – 1.03 0.66 4404 33771 all phecode
742.1 Loose body in joint Musculoskeletal 1.11 0.935 – 1.32 0.231 156 1554 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.9 0.793 – 1.02 0.107 280 2792 all phecode
742.8 Articular cartilage disorder Musculoskeletal 0.982 0.856 – 1.13 0.795 245 2450 all phecode
742.9 Other derangement of joint Musculoskeletal 0.998 0.965 – 1.03 0.917 4107 32972 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.939 0.916 – 0.963 1.22e-06 9223 36921 all phecode
743.1 Osteoporosis Musculoskeletal 0.919 0.884 – 0.955 1.94e-05 3712 19477 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.916 0.881 – 0.953 1.24e-05 3657 19276 all phecode
743.12 Senile osteoporosis Musculoskeletal 0.833 0.765 – 0.907 2.77e-05 703 5804 all phecode
743.13 Other specified osteoporosis Musculoskeletal 0.907 0.802 – 1.03 0.12 321 3141 all phecode
743.2 Pathologic fracture Musculoskeletal 0.931 0.872 – 0.995 0.0354 1112 10563 all phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 0.962 0.87 – 1.06 0.455 475 4629 all phecode
743.22 Pathologic fracture of femur Musculoskeletal 0.95 0.79 – 1.14 0.588 143 1391 all phecode
743.4 Stress fracture Musculoskeletal 0.923 0.828 – 1.03 0.148 407 4046 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.927 0.902 – 0.954 1.5e-07 6970 35237 all phecode
745 Pain in joint Musculoskeletal 0.992 0.973 – 1.01 0.423 19848 26918 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.01 0.962 – 1.05 0.75 2236 22256 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.04 0.991 – 1.1 0.109 1767 17598 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.978 0.899 – 1.06 0.606 650 6497 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.09 1 – 1.18 0.0383 751 7480 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.08 0.969 – 1.2 0.166 410 4090 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.918 0.834 – 1.01 0.0786 501 5010 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.03 0.842 – 1.26 0.77 111 1110 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.914 0.834 – 1 0.0573 555 5549 all phecode
749.1 Cleft palate Congenital Anomalies 0.798 0.646 – 0.986 0.0369 97 970 all phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.962 0.779 – 1.19 0.719 105 1041 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.955 0.888 – 1.03 0.209 893 8919 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.917 0.82 – 1.03 0.131 366 3655 all phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.922 0.759 – 1.12 0.411 119 1185 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.898 0.721 – 1.12 0.341 99 982 all phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 0.865 0.72 – 1.04 0.119 134 1332 all phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 0.988 0.748 – 1.3 0.933 60 593 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.968 0.881 – 1.06 0.504 531 5300 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.909 0.805 – 1.03 0.123 313 3129 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.07 0.92 – 1.24 0.391 222 2214 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1 0.957 – 1.05 0.865 2008 19975 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.986 0.901 – 1.08 0.762 574 5740 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.02 0.915 – 1.14 0.693 384 3840 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.908 0.766 – 1.08 0.267 153 1527 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.02 0.963 – 1.08 0.478 1379 13704 all phecode
751.21 Cystic kidney disease Congenital Anomalies 1 0.935 – 1.07 0.939 976 9685 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.02 0.899 – 1.15 0.774 294 2927 all phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.05 0.893 – 1.22 0.581 182 1809 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.13 1.06 – 1.2 0.000235 1133 11313 all phecode
752.1 Neural tube defects Congenital Anomalies 1.15 1.07 – 1.23 0.00013 923 9209 all phecode
752.11 Spina bifida Congenital Anomalies 1.09 0.932 – 1.28 0.272 176 1760 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.03 0.896 – 1.19 0.668 232 2320 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.06 0.904 – 1.23 0.494 207 2051 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.03 0.772 – 1.38 0.831 58 580 all phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 0.981 0.734 – 1.31 0.899 56 546 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.12 1.05 – 1.19 0.000558 1216 12116 all phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 1.09 0.905 – 1.32 0.353 135 1333 all phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 1.11 1.02 – 1.22 0.0227 558 5570 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.02 0.941 – 1.1 0.635 747 7458 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.02 0.914 – 1.14 0.709 368 3663 all phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 0.955 0.749 – 1.22 0.709 74 740 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.02 0.9 – 1.15 0.787 321 3205 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.02 0.865 – 1.19 0.845 185 1847 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.957 0.903 – 1.01 0.139 1358 13579 all phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.897 0.693 – 1.16 0.408 68 680 all phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 1 0.78 – 1.29 0.993 71 694 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.924 0.823 – 1.04 0.183 335 3346 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.971 0.908 – 1.04 0.4 1003 10014 all phecode
757 Congenital anomalies of the integument Congenital Anomalies 0.867 0.778 – 0.967 0.01 401 4001 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.877 0.749 – 1.03 0.1 185 1845 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.909 0.757 – 1.09 0.304 135 1349 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.97 0.886 – 1.06 0.514 557 5566 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.896 0.692 – 1.16 0.403 71 710 all phecode
760 Back pain Symptoms 1.07 1.05 – 1.09 7.03e-11 16037 30719 all phecode
761 Cervicalgia Symptoms 1.02 0.992 – 1.05 0.173 6528 39755 all phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 1.05 1.01 – 1.09 0.00635 3657 32599 all phecode
764 Sciatica Symptoms 1.08 1.04 – 1.12 3.18e-05 3542 32015 all phecode
765 Cervical radiculitis Symptoms 1.04 0.986 – 1.09 0.159 1799 17851 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.06 1.03 – 1.09 0.000194 5124 37132 all phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.03 0.849 – 1.24 0.794 117 1168 all phecode
769 Nonallopathic lesions NEC Symptoms 1 0.937 – 1.07 0.993 1131 11220 all phecode
770 Myalgia and myositis unspecified Symptoms 1.07 1.04 – 1.1 1.54e-05 5533 34303 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.08 1.04 – 1.11 7.62e-06 4799 35575 all phecode
771.1 Swelling of limb Symptoms 1.13 1.1 – 1.17 1.73e-16 5743 35539 all phecode
771.2 Cramp of limb Symptoms 1.06 0.993 – 1.13 0.0819 1079 10568 all phecode
772 Symptoms of the muscles Symptoms 0.924 0.881 – 0.97 0.00139 2042 20221 all phecode
772.1 Muscular wasting and disuse atrophy Symptoms 0.929 0.835 – 1.03 0.179 422 4199 all phecode
772.2 Spasm of muscle Symptoms 1 0.958 – 1.05 0.919 2299 22726 all phecode
772.3 Muscle weakness Symptoms 1.06 1.02 – 1.11 0.00349 2949 28064 all phecode
772.4 Rhabdomyolysis Symptoms 1.11 0.936 – 1.32 0.225 159 1572 all phecode
772.6 Facial weakness Symptoms 0.986 0.892 – 1.09 0.786 478 4742 all phecode
780 Hypothermia/Chills Symptoms 1.02 0.919 – 1.13 0.748 453 4514 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.03 0.988 – 1.07 0.173 2822 26225 all phecode
781.1 Loss of height Symptoms 0.985 0.811 – 1.2 0.876 130 1269 all phecode
781.2 Abnormal posture Symptoms 0.953 0.719 – 1.26 0.739 57 567 all phecode
782.3 Edema Symptoms 1.18 1.15 – 1.22 1.56e-28 5874 36788 all phecode
782.6 Pallor and flushing Symptoms 0.918 0.854 – 0.986 0.0189 927 9252 all phecode
783 Fever of unknown origin Symptoms 1.07 1.04 – 1.1 1.15e-05 5733 40720 all phecode
783.1 Postprocedural fever Symptoms 1.11 0.981 – 1.26 0.0975 300 2992 all phecode
785 Abdominal pain Symptoms 1.05 1.03 – 1.07 8.49e-06 16458 30297 all phecode
788 Syncope and collapse Symptoms 1.02 0.981 – 1.05 0.362 3851 35832 all phecode
789 Nausea and vomiting Symptoms 1.05 1.03 – 1.08 7.56e-06 10568 36098 all phecode
789.1 Persistent vomiting Symptoms 1.19 1.1 – 1.28 7.65e-06 798 7924 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.07 1.02 – 1.12 0.00314 2363 22690 all phecode
790.1 Elevated sedimentation rate Symptoms 1.16 1 – 1.33 0.0489 236 2322 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.08 1.05 – 1.11 5.59e-08 7539 37788 all phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 1.17 1.04 – 1.32 0.0111 309 3075 all phecode
790.9 Abnormal arterial blood gases Symptoms 1.19 0.996 – 1.42 0.055 155 1521 all phecode
791 Gangrene Symptoms 1.11 0.987 – 1.26 0.0811 313 3115 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 0.986 0.945 – 1.03 0.526 2820 14872 all phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 0.989 0.926 – 1.06 0.749 1100 9861 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.987 0.897 – 1.09 0.783 515 5133 all phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 0.985 0.94 – 1.03 0.541 2182 20242 all phecode
795.8 Abnormal tumor markers Symptoms 0.905 0.859 – 0.954 0.000172 1745 15551 all phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 1.17 0.895 – 1.52 0.254 61 605 all phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 0.877 0.753 – 1.02 0.0947 201 2000 all phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.876 0.833 – 0.921 2.38e-07 2125 9930 all phecode
797 Shock Symptoms 1.08 0.992 – 1.18 0.0741 605 6050 all phecode
797.1 Cardiogenic shock Symptoms 1.19 1.04 – 1.37 0.0135 242 2420 all phecode
798 Malaise and fatigue Symptoms 1.02 0.995 – 1.04 0.137 11539 35196 all phecode
798.1 Chronic fatigue syndrome Symptoms 1.01 0.958 – 1.06 0.762 1823 17795 all phecode
800 Fracture of lower limb Injuries & Poisonings 0.994 0.951 – 1.04 0.801 2344 22951 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.962 0.873 – 1.06 0.443 512 4961 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.971 0.892 – 1.06 0.502 670 6582 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.04 0.972 – 1.12 0.242 898 8966 all phecode
800.4 Fracture of patella Injuries & Poisonings 0.962 0.857 – 1.08 0.514 346 3456 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.01 0.965 – 1.06 0.703 2358 22645 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.03 0.966 – 1.1 0.365 1120 11178 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.918 0.821 – 1.03 0.132 380 3765 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.923 0.88 – 0.968 0.000977 2051 20360 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.02 0.942 – 1.11 0.613 734 7322 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.916 0.858 – 0.977 0.00773 1112 11075 all phecode
803.21 Colles' fracture Injuries & Poisonings 0.863 0.761 – 0.98 0.0228 291 2904 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.833 0.758 – 0.916 0.000153 514 5140 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.927 0.879 – 0.978 0.00573 1628 16042 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.01 0.947 – 1.07 0.869 1336 13242 all phecode
807 Fracture of ribs Injuries & Poisonings 0.967 0.891 – 1.05 0.428 683 6815 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.965 0.928 – 1 0.0833 2941 28633 all phecode
816 Cerebral laceration and contusion Injuries & Poisonings 1.31 0.978 – 1.76 0.0701 54 531 all phecode
817 Concussion Injuries & Poisonings 1.02 0.949 – 1.09 0.661 1018 10149 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.87 0.77 – 0.983 0.0251 311 3104 all phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 0.945 0.759 – 1.18 0.616 90 895 all phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 0.916 0.735 – 1.14 0.436 97 970 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.964 0.922 – 1.01 0.117 2287 22671 all phecode
830 Dislocation Injuries & Poisonings 0.956 0.923 – 0.99 0.0111 3862 34720 all phecode
835 Internal derangement of knee Injuries & Poisonings 0.998 0.953 – 1.05 0.934 2231 21628 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.09 0.989 – 1.2 0.0833 496 4954 all phecode
840 Sprains and strains Injuries & Poisonings 0.976 0.951 – 1 0.0652 7838 37998 all phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 0.999 0.91 – 1.1 0.978 537 5356 all phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 1.01 0.959 – 1.07 0.659 1640 16263 all phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.943 0.905 – 0.982 0.00439 2875 24879 all phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.991 0.939 – 1.05 0.759 1583 15592 all phecode
842 Other sprains and strains Injuries & Poisonings 0.974 0.919 – 1.03 0.364 1407 13924 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.08 1.03 – 1.13 0.00272 2072 20649 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.14 1.09 – 1.19 1.28e-10 2982 27545 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.04 0.941 – 1.15 0.452 460 4600 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.14 1.09 – 1.2 8.93e-08 1985 19675 all phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.07 0.937 – 1.22 0.318 264 2640 all phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.07 0.942 – 1.22 0.299 293 2929 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.11 1.04 – 1.18 0.000883 1310 13087 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.07 1.02 – 1.12 0.00637 2213 21944 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.08 1.03 – 1.13 0.00212 2110 21070 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1.06 0.899 – 1.25 0.481 166 1660 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.02 0.983 – 1.05 0.322 4117 36734 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.02 0.876 – 1.19 0.805 204 2026 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.889 0.746 – 1.06 0.191 144 1437 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.878 0.828 – 0.931 1.49e-05 1346 13301 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.918 0.792 – 1.06 0.255 207 2057 all phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 0.907 0.795 – 1.04 0.149 275 2724 all phecode
870.6 Open wound of neck Injuries & Poisonings 0.954 0.824 – 1.11 0.534 214 2128 all phecode
870.8 Open wound of genital organs Injuries & Poisonings 1.19 0.993 – 1.42 0.0595 144 1440 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.05 1.01 – 1.09 0.0111 3530 32903 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.02 0.934 – 1.12 0.631 572 5701 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.959 0.895 – 1.03 0.24 984 9772 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.31 1.19 – 1.45 3.84e-08 490 4843 all phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.19 1.05 – 1.35 0.00758 295 2921 all phecode
872 Traumatic amputation Injuries & Poisonings 1.19 1.08 – 1.3 0.000284 551 5477 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.23 1.04 – 1.45 0.0134 170 1697 all phecode
875 Non-healing surgical wound Injuries & Poisonings 1.17 1.07 – 1.28 0.000534 572 5720 all phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.24 1.15 – 1.34 3.05e-08 802 8003 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.04 0.971 – 1.11 0.274 1010 10096 all phecode
910 Superficial injury, infected Injuries & Poisonings 0.889 0.729 – 1.08 0.243 119 1161 all phecode
911 Blister Injuries & Poisonings 1.2 1.06 – 1.36 0.00444 302 2996 all phecode
912 Insect bite Injuries & Poisonings 0.988 0.895 – 1.09 0.819 492 4886 all phecode
913 Toxic effect of venom Injuries & Poisonings 0.806 0.716 – 0.908 0.000374 337 3326 all phecode
916 Contusion Injuries & Poisonings 1.04 1.01 – 1.08 0.018 4296 38033 all phecode
930 Allergic reaction to food Injuries & Poisonings 1.01 0.932 – 1.09 0.854 763 7596 all phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.921 0.848 – 0.999 0.0474 714 7072 all phecode
938 Dermatitis due to solar radiation Dermatologic 0.896 0.869 – 0.924 2.98e-12 5567 29098 all phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.93 0.802 – 1.08 0.334 217 2164 all phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.889 0.862 – 0.918 3.31e-13 5307 28656 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.99 0.962 – 1.02 0.469 6704 32389 all phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 0.977 0.775 – 1.23 0.843 91 870 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.05 0.894 – 1.22 0.576 188 1880 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.04 0.905 – 1.18 0.613 269 2688 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.949 0.861 – 1.04 0.285 500 4940 all phecode
947 Urticaria Dermatologic 0.995 0.933 – 1.06 0.868 1177 11454 all phecode
949 Allergies, other Injuries & Poisonings 1.02 0.992 – 1.05 0.157 7251 32350 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.1 1 – 1.21 0.0495 494 4940 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.897 0.749 – 1.08 0.242 136 1352 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.06 0.997 – 1.13 0.0644 1217 12158 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.02 0.866 – 1.21 0.8 169 1688 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.975 0.797 – 1.19 0.809 114 1140 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.14 1.09 – 1.19 1e-08 2479 22087 all phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 1.17 1.04 – 1.32 0.00988 342 3403 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.15 1.09 – 1.22 2.54e-07 1636 16005 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.1 1.01 – 1.21 0.0388 528 5234 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.13 1.06 – 1.21 0.000314 1065 10347 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.08 0.999 – 1.16 0.0525 803 7976 all phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.09 0.973 – 1.22 0.138 379 3782 all phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 1.27 0.967 – 1.67 0.0858 62 612 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.07 0.974 – 1.19 0.152 478 4773 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.03 0.985 – 1.07 0.198 2533 24531 all phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.03 0.989 – 1.08 0.149 2469 24057 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.08 0.998 – 1.17 0.0563 743 7337 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.09 1 – 1.18 0.0405 712 7027 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.03 0.952 – 1.1 0.512 864 8601 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.16 1.1 – 1.23 1.83e-07 1469 14402 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.957 0.786 – 1.17 0.663 119 1182 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.936 0.76 – 1.15 0.537 103 1006 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.993 0.934 – 1.06 0.831 1254 12464 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.13 0.997 – 1.29 0.0552 281 2797 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.19 0.917 – 1.53 0.194 67 643 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.19 1.05 – 1.35 0.00726 288 2858 all phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 1.23 0.971 – 1.56 0.0866 80 776 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.18 0.968 – 1.44 0.1 104 1034 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.06 0.87 – 1.3 0.554 113 1130 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.12 0.884 – 1.42 0.345 81 810 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.11 0.857 – 1.43 0.437 71 703 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.1 1.04 – 1.16 0.000453 1763 16599 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.03 0.992 – 1.07 0.128 3448 30885 all phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 1.01 0.954 – 1.07 0.699 1391 13877 all phecode
985 Toxic effect of other metals Injuries & Poisonings 1.31 0.986 – 1.73 0.0622 57 564 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.973 0.807 – 1.17 0.779 129 1275 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.02 0.988 – 1.06 0.189 3927 31223 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.15 1.1 – 1.2 5.39e-09 2192 21710 all phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.16 1.02 – 1.31 0.0264 291 2910 all phecode
994.2 Sepsis Injuries & Poisonings 1.14 1.09 – 1.2 4.48e-08 2086 20666 all phecode
994.21 Septic shock Injuries & Poisonings 1.17 1.07 – 1.27 0.000593 627 6260 all phecode
008 Intestinal infection Infectious Diseases 1.02 0.945 – 1.11 0.568 745 6950 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.22 1.08 – 1.38 0.00168 321 2987 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.21 1.05 – 1.39 0.00838 251 2331 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.06 0.903 – 1.25 0.463 168 1792 exclusion phecode
010 Tuberculosis Infectious Diseases 0.998 0.767 – 1.3 0.991 61 539 exclusion phecode
031 Diseases due to other mycobacteria Infectious Diseases 1 0.667 – 1.5 0.999 27 197 exclusion phecode
038 Septicemia Infectious Diseases 1.27 1.16 – 1.39 5.59e-07 551 5136 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.3 1.06 – 1.58 0.012 115 1172 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.13 0.838 – 1.53 0.418 50 455 exclusion phecode
038.3 Bacteremia Infectious Diseases 1.26 1.1 – 1.44 0.000861 266 2396 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.13 1.07 – 1.2 6.41e-05 1319 9006 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.26 1.12 – 1.41 8.1e-05 349 3617 exclusion phecode
041.11 Methicillin sensitive Staphylococcus aureus Infectious Diseases 1.35 1.15 – 1.58 0.00024 181 1916 exclusion phecode
041.12 Methicillin resistant Staphylococcus aureus Infectious Diseases 1.3 1.1 – 1.54 0.00225 157 1700 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.24 1.11 – 1.39 0.000149 381 3462 exclusion phecode
041.21 Rheumatic fever / chorea Infectious Diseases 1.1 0.805 – 1.5 0.551 50 554 exclusion phecode
041.4 E. coli Infectious Diseases 1.16 1.01 – 1.33 0.0367 260 2614 exclusion phecode
041.8 H. pylori Infectious Diseases 0.929 0.704 – 1.23 0.604 58 595 exclusion phecode
041.9 Infection with drug-resistant microorganisms Infectious Diseases 1.37 1.09 – 1.72 0.00708 96 849 exclusion phecode
053 Herpes zoster Infectious Diseases 0.905 0.808 – 1.01 0.0879 369 3324 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.02 0.749 – 1.39 0.898 50 459 exclusion phecode
054 Herpes simplex Infectious Diseases 0.994 0.894 – 1.11 0.917 422 3794 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.12 0.953 – 1.32 0.168 193 1614 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 2.04 1.02 – 4.11 0.0452 11 160 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 1.11 0.816 – 1.5 0.511 52 441 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.23 1.02 – 1.5 0.0324 129 966 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.17 0.856 – 1.61 0.318 53 395 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.16 1.01 – 1.33 0.0379 245 2187 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.58 1.17 – 2.13 0.00265 59 289 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.63 1.18 – 2.25 0.00281 50 218 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.903 0.839 – 0.971 0.00605 911 7141 exclusion phecode
079 Viral infection Infectious Diseases 1.01 0.953 – 1.06 0.806 1707 8160 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.915 0.852 – 0.982 0.0143 975 7161 exclusion phecode
079.2 Infectious mononucleosis Infectious Diseases 0.824 0.669 – 1.02 0.0688 106 885 exclusion phecode
079.9 Viremia, NOS Infectious Diseases 1.29 1.11 – 1.5 0.000738 214 2028 exclusion phecode
080 Postoperative infection Infectious Diseases 1.16 1.06 – 1.27 0.00174 540 5845 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.22 1.1 – 1.37 0.000322 389 3473 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.1 0.969 – 1.26 0.138 277 2444 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.997 0.915 – 1.09 0.939 644 6718 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.99 0.904 – 1.09 0.833 555 6022 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.989 0.88 – 1.11 0.857 340 3534 exclusion phecode
110.12 Althete's foot Infectious Diseases 1 0.829 – 1.21 0.983 129 1645 exclusion phecode
110.13 Dermatophytosis of the body Infectious Diseases 0.906 0.754 – 1.09 0.295 131 1711 exclusion phecode
110.2 Dermatomycoses Infectious Diseases 1.06 0.859 – 1.31 0.58 103 952 exclusion phecode
112 Candidiasis Infectious Diseases 1.16 1.07 – 1.25 0.00011 876 7564 exclusion phecode
112.3 Candidiasis of skin and nails Infectious Diseases 0.974 0.741 – 1.28 0.853 57 1616 exclusion phecode
117 Mycoses Infectious Diseases 1.12 0.943 – 1.33 0.199 164 1439 exclusion phecode
117.1 Histoplasmosis Infectious Diseases 1.21 0.788 – 1.85 0.388 23 193 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.33 0.988 – 1.8 0.0603 49 340 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.913 0.674 – 1.24 0.554 48 434 exclusion phecode
130.1 Lyme disease Infectious Diseases 0.889 0.635 – 1.24 0.49 38 309 exclusion phecode
131 Protozoan infection Infectious Diseases 1.59 0.907 – 2.79 0.105 11 163 exclusion phecode
132 Infestation (lice, mites) Infectious Diseases 1.3 0.954 – 1.77 0.0968 46 468 exclusion phecode
134 Helminthiases Infectious Diseases 1.22 0.791 – 1.88 0.368 22 177 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.3 0.741 – 2.28 0.362 16 108 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.16 1.07 – 1.25 0.00014 854 7457 exclusion phecode
145 Cancer of mouth Neoplasms 1.31 1.17 – 1.46 1.79e-06 402 2723 exclusion phecode
145.1 Cancer of lip Neoplasms 1.56 0.935 – 2.61 0.0885 16 137 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.34 1.14 – 1.58 0.000392 186 1121 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.923 0.725 – 1.18 0.518 79 717 exclusion phecode
145.4 Cancer of the gums Neoplasms 1.7 1.23 – 2.35 0.00132 54 343 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.62 1.24 – 2.12 0.000381 75 363 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.35 1.2 – 1.52 8.14e-07 355 2312 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.66 1.31 – 2.1 2.36e-05 105 568 exclusion phecode
149.2 Cancer of nasopharynx Neoplasms 1.5 0.986 – 2.27 0.058 33 211 exclusion phecode
149.3 Cancer of hypopharynx Neoplasms 1.58 1.05 – 2.4 0.0298 28 154 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.44 1.15 – 1.79 0.00128 102 636 exclusion phecode
149.5
Hx of malignant neoplasm of oral cavity and
Hx of malignant neoplasm of oral cavity and pharynx
 Neoplasms 1.39 1.16 – 1.68 0.000393 148 971 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.13 0.846 – 1.52 0.401 60 466 exclusion phecode
150 Cancer of esophagus Neoplasms 1.56 1.26 – 1.93 4.39e-05 99 751 exclusion phecode
151 Cancer of stomach Neoplasms 1.09 0.887 – 1.35 0.405 112 884 exclusion phecode
153 Colorectal cancer Neoplasms 1.03 0.914 – 1.17 0.589 307 2977 exclusion phecode
153.2 Colon cancer Neoplasms 1.02 0.883 – 1.18 0.774 224 2327 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1 0.855 – 1.17 0.987 194 1749 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.2 0.968 – 1.49 0.0961 109 958 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.21 0.933 – 1.57 0.152 72 634 exclusion phecode
157 Pancreatic cancer Neoplasms 1.28 1.04 – 1.57 0.0207 119 943 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.05 0.935 – 1.18 0.412 366 3192 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.14 1.02 – 1.28 0.0167 398 3485 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.94 0.672 – 1.32 0.72 44 428 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.18 0.842 – 1.64 0.342 44 300 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.19 0.922 – 1.55 0.18 74 624 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.965 0.663 – 1.4 0.851 36 255 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.19 1.06 – 1.35 0.00452 327 2562 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.13 0.986 – 1.3 0.0787 254 2026 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 1.11 1 – 1.23 0.0436 438 3720 exclusion phecode
170.1 Bone cancer Neoplasms 1.23 1.06 – 1.43 0.00664 205 1645 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1.07 0.941 – 1.21 0.309 295 2650 exclusion phecode
172 Skin cancer Neoplasms 0.967 0.915 – 1.02 0.221 2005 7136 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.912 0.853 – 0.975 0.00718 1183 6208 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.872 0.798 – 0.952 0.00215 622 5040 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.971 0.916 – 1.03 0.325 1698 6245 exclusion phecode
172.21 Basal cell carcinoma Neoplasms 0.899 0.832 – 0.97 0.00639 900 4642 exclusion phecode
172.22 Squamous cell carcinoma Neoplasms 1.06 0.965 – 1.16 0.227 583 3196 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.864 0.767 – 0.973 0.0155 363 2293 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.916 0.828 – 1.01 0.0887 472 3913 exclusion phecode
174 Breast cancer Neoplasms 0.906 0.84 – 0.977 0.0108 942 4018 exclusion phecode
174.1 Breast cancer [female] Neoplasms 0.912 0.844 – 0.986 0.0199 905 3840 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.916 0.847 – 0.991 0.0286 886 3818 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.681 0.516 – 0.898 0.0066 65 592 exclusion phecode
175 Acquired absence of breast Neoplasms 0.887 0.78 – 1.01 0.0664 301 2272 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.04 0.934 – 1.15 0.491 442 3333 exclusion phecode
180.1 Cervical cancer Neoplasms 1.12 0.927 – 1.34 0.245 135 1295 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.986 0.878 – 1.11 0.815 356 2584 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.991 0.806 – 1.22 0.935 105 1877 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.04 0.914 – 1.17 0.576 313 2979 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.947 0.791 – 1.13 0.555 151 1504 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.945 0.773 – 1.16 0.581 120 1139 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.15 0.957 – 1.37 0.138 150 1531 exclusion phecode
185 Cancer of prostate Neoplasms 0.901 0.796 – 1.02 0.0988 399 1589 exclusion phecode
187 Cancer of other male genital organs Neoplasms 0.869 0.662 – 1.14 0.31 66 631 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.08 0.635 – 1.82 0.784 14 181 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.73 0.53 – 1.01 0.0538 42 389 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.26 0.651 – 2.44 0.494 12 97 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.07 0.966 – 1.18 0.201 474 4570 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.09 0.941 – 1.26 0.254 217 2783 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.08 0.922 – 1.27 0.33 179 2436 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.46 1.03 – 2.07 0.0315 43 421 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.09 0.959 – 1.23 0.196 307 2791 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.13 0.989 – 1.28 0.0723 290 2565 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.32 1.08 – 1.62 0.0065 116 1178 exclusion phecode
190 Cancer of eye Neoplasms 0.902 0.642 – 1.27 0.551 44 274 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.03 0.905 – 1.18 0.627 257 2389 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.977 0.837 – 1.14 0.769 189 1564 exclusion phecode
191.11 Cancer of brain Neoplasms 1.03 0.871 – 1.21 0.738 166 1311 exclusion phecode
193 Thyroid cancer Neoplasms 1.06 0.901 – 1.24 0.5 180 2295 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.1 0.895 – 1.35 0.368 115 1361 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.03 0.983 – 1.08 0.218 3803 6337 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.02 0.978 – 1.07 0.316 3739 6336 exclusion phecode
195.3 Malignant neoplasm of head, face, and neck Neoplasms 1.34 1.17 – 1.53 2.15e-05 276 1686 exclusion phecode
196 Radiotherapy Neoplasms 1.04 0.941 – 1.14 0.478 560 3437 exclusion phecode
197 Chemotherapy Neoplasms 1.12 1.05 – 1.2 0.000866 1227 5333 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.12 1.05 – 1.2 0.000744 1285 5236 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.11 1.02 – 1.2 0.0132 840 4617 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.3 1.12 – 1.5 0.00061 218 1968 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.09 0.942 – 1.27 0.238 220 1681 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.13 0.962 – 1.33 0.136 193 1429 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.23 1.03 – 1.47 0.0201 154 1229 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.4 1.19 – 1.64 5.1e-05 188 1540 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.09 0.848 – 1.4 0.505 81 608 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.05 0.985 – 1.12 0.131 1222 6068 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.52 1.03 – 2.25 0.034 30 219 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.2 1.05 – 1.37 0.00916 259 2376 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.24 0.891 – 1.72 0.204 43 384 exclusion phecode
201 Hodgkin's disease Neoplasms 1.37 1.03 – 1.84 0.032 47 409 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.19 1.06 – 1.33 0.00271 375 3286 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.19 1.05 – 1.34 0.00578 318 2810 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.16 0.984 – 1.36 0.0778 183 1510 exclusion phecode
202.22 Reticulosarcoma Neoplasms 1.01 0.71 – 1.44 0.944 36 352 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.02 0.711 – 1.45 0.935 38 319 exclusion phecode
204 Leukemia Neoplasms 1.04 0.87 – 1.23 0.698 153 1343 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1.08 0.807 – 1.45 0.597 58 448 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.22 0.758 – 1.96 0.413 21 173 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.921 0.638 – 1.33 0.66 38 313 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.07 0.816 – 1.41 0.619 62 505 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.95 0.657 – 1.37 0.785 36 268 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.04 0.61 – 1.77 0.888 16 128 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.07 0.77 – 1.48 0.696 42 438 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1.02 0.965 – 1.07 0.56 2119 8346 exclusion phecode
209 Neuroendocrine tumors Neoplasms 1.15 0.827 – 1.61 0.401 41 515 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.04 0.941 – 1.15 0.451 499 4205 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.09 1.03 – 1.16 0.0023 1559 8697 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.19 1.07 – 1.32 0.000898 437 3952 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.01 0.904 – 1.12 0.913 415 3699 exclusion phecode
214 Lipoma Neoplasms 1.04 0.911 – 1.19 0.545 260 3192 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.01 0.85 – 1.19 0.946 160 2008 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.99 0.925 – 1.06 0.779 1012 9144 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.912 0.871 – 0.955 8.88e-05 2817 8094 exclusion phecode
216.1 Screening for malignant neoplasms of the skin Neoplasms 1.3 0.929 – 1.82 0.125 45 416 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.838 0.759 – 0.925 0.000443 502 3752 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.835 0.754 – 0.925 0.000577 464 3438 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.917 0.856 – 0.982 0.0136 1154 4797 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.854 0.77 – 0.947 0.00268 461 4411 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.918 0.852 – 0.989 0.024 944 4715 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.919 0.795 – 1.06 0.252 226 2392 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.959 0.869 – 1.06 0.398 506 4088 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.749 0.638 – 0.88 0.000422 182 1720 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.06 0.937 – 1.2 0.356 326 2723 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.891 0.749 – 1.06 0.194 161 1399 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.898 0.745 – 1.08 0.262 134 1127 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.09 0.955 – 1.23 0.207 275 2764 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.998 0.862 – 1.15 0.975 213 2174 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.3 1.01 – 1.67 0.0386 71 639 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.05 0.923 – 1.2 0.442 259 3226 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.03 0.91 – 1.17 0.61 283 3878 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.07 0.818 – 1.39 0.634 63 965 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.03 0.872 – 1.23 0.703 157 1863 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.892 0.689 – 1.15 0.383 63 1012 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.797 0.724 – 0.877 3.65e-06 538 4535 exclusion phecode
228.1 Hemangioma of skin and subcutaneous tissue Neoplasms 0.742 0.659 – 0.836 9.66e-07 355 2832 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.983 0.93 – 1.04 0.536 1669 8554 exclusion phecode
229.1 Benign neoplasm of lymph nodes Neoplasms 0.979 0.918 – 1.04 0.507 1210 7778 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.09 0.943 – 1.26 0.24 219 2530 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.05 0.959 – 1.15 0.295 605 5567 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.02 0.922 – 1.13 0.705 475 4945 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.08 0.937 – 1.24 0.293 236 3181 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.07 0.948 – 1.22 0.262 299 3335 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.924 0.758 – 1.13 0.433 118 1249 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.41 0.867 – 2.3 0.166 19 307 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.88 0.685 – 1.13 0.316 72 698 exclusion phecode
242.31 Thyrotoxic exophthalmos Endocrine/metabolic 0.904 0.635 – 1.29 0.573 38 356 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.03 0.976 – 1.1 0.248 1647 7677 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.997 0.89 – 1.12 0.959 351 4262 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.13 0.993 – 1.28 0.0633 284 3037 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.04 0.976 – 1.1 0.24 1538 7562 exclusion phecode
245 Thyroiditis Endocrine/metabolic 1.31 1.11 – 1.54 0.00123 178 2110 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.37 1.14 – 1.64 0.000887 138 1770 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.37 1.14 – 1.64 0.000878 137 1751 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.03 0.962 – 1.09 0.436 1301 7120 exclusion phecode
246.2 Thyroid cyst Endocrine/metabolic 0.824 0.54 – 1.26 0.371 25 228 exclusion phecode
246.7 Abnormal results of function study of thyroid Endocrine/metabolic 1.05 0.903 – 1.21 0.543 218 2156 exclusion phecode
249 Secondary diabetes mellitus Endocrine/metabolic 1.18 0.974 – 1.44 0.0904 169 1894 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.1 1.03 – 1.16 0.0023 1798 8752 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.18 1.02 – 1.37 0.0277 469 2920 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.8 1.24 – 2.61 0.00192 103 226 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.23 0.966 – 1.56 0.0934 154 616 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.35 1.05 – 1.74 0.0188 189 705 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.45 1.12 – 1.86 0.00406 160 588 exclusion phecode
250.15
Diabetes type 1 with peripheral circulatory
Diabetes type 1 with peripheral circulatory disorders
 Endocrine/metabolic 1.29 0.892 – 1.86 0.177 49 173 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.15 1.06 – 1.24 0.000543 1078 7827 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.63 1.11 – 2.41 0.0134 77 288 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.43 1.19 – 1.72 0.000155 173 3130 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.24 1.02 – 1.5 0.0345 207 2284 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.24 1.04 – 1.49 0.0171 215 3893 exclusion phecode
250.25
Diabetes type 2 with peripheral circulatory
Diabetes type 2 with peripheral circulatory disorders
 Endocrine/metabolic 1.22 0.939 – 1.57 0.139 71 1331 exclusion phecode
250.3 Insulin pump user Endocrine/metabolic 1.27 1.11 – 1.46 0.000629 438 5081 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.07 0.995 – 1.15 0.0683 1238 8248 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.01 0.868 – 1.17 0.906 232 4125 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.08 1 – 1.16 0.039 1125 7996 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.93 1.16 – 3.21 0.0108 26 290 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.27 1.04 – 1.54 0.0173 205 3102 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.13 0.973 – 1.31 0.108 256 2093 exclusion phecode
251 Other disorders of pancreatic internal secretion Endocrine/metabolic 1.12 0.976 – 1.29 0.105 245 1974 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.18 1.02 – 1.36 0.0297 310 2348 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.1 0.997 – 1.22 0.0566 477 5165 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.1 0.988 – 1.22 0.0844 435 4715 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.24 0.998 – 1.55 0.0522 98 1179 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.02 0.865 – 1.2 0.812 164 1895 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.08 0.801 – 1.46 0.612 48 670 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.858 0.497 – 1.48 0.585 11 203 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.86 0.612 – 1.21 0.387 32 477 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.21 0.741 – 1.99 0.443 15 182 exclusion phecode
253.4 Anterior pituitary disorders Endocrine/metabolic 0.866 0.53 – 1.42 0.567 18 220 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.23 0.816 – 1.86 0.321 30 242 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.11 0.976 – 1.26 0.114 276 3379 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.961 0.729 – 1.27 0.78 56 924 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.7 0.466 – 1.05 0.0849 26 495 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.29 0.777 – 2.15 0.324 15 281 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.15 0.951 – 1.39 0.151 131 1432 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.18 0.971 – 1.43 0.0963 123 1361 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.927 0.807 – 1.06 0.284 237 3240 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.821 0.647 – 1.04 0.104 78 2257 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1.06 0.88 – 1.27 0.545 127 1530 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.05 0.874 – 1.27 0.584 122 1469 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.38 0.831 – 2.27 0.215 17 186 exclusion phecode
258.1 Postablative ovarian failure Endocrine/metabolic 0.988 0.671 – 1.45 0.95 31 330 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 1.08 0.924 – 1.25 0.345 201 2439 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.3 1.21 – 1.39 2.12e-12 988 5553 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.45 1.17 – 1.78 5e-04 147 559 exclusion phecode
260.2 severe protein-calorie malnutrition Endocrine/metabolic 1.44 1.31 – 1.58 2.85e-14 600 3325 exclusion phecode
260.22 Nutritional marasmus Endocrine/metabolic 1.42 1.21 – 1.66 1.65e-05 214 1201 exclusion phecode
260.3 Adult failure to thrive Endocrine/metabolic 1.4 1.19 – 1.64 3.62e-05 210 1199 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.28 1.11 – 1.46 0.000416 264 1878 exclusion phecode
260.7 Polyphagia Endocrine/metabolic 0.908 0.531 – 1.55 0.724 16 167 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.15 1.08 – 1.21 3.48e-06 1599 8182 exclusion phecode
261.1 Vitamin A deficiency Endocrine/metabolic 1.57 0.99 – 2.48 0.0553 22 160 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.3 1.1 – 1.53 0.0023 175 1833 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.15 1.08 – 1.22 4.59e-06 1500 8199 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.837 0.507 – 1.38 0.489 14 118 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.24 1.09 – 1.42 0.00155 269 2874 exclusion phecode
263 Other nutritional deficiency Endocrine/metabolic 1.27 1.13 – 1.42 3.43e-05 368 3637 exclusion phecode
264 Lack of normal physiological development Endocrine/metabolic 1.09 0.874 – 1.35 0.459 103 699 exclusion phecode
264.2 Failure to thrive (childhood) Endocrine/metabolic 1.12 0.818 – 1.54 0.472 51 309 exclusion phecode
264.9
Lack of normal physiological development
Lack of normal physiological development, unspecified
 Endocrine/metabolic 0.986 0.698 – 1.39 0.938 38 286 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.35 1.19 – 1.53 5.11e-06 286 3036 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.18 1.02 – 1.37 0.0302 201 2098 exclusion phecode
270.1 Disturbances of amino-acid transport Endocrine/metabolic 0.99 0.695 – 1.41 0.956 34 418 exclusion phecode
270.11
Disturbances of sulphur-bearing amino-acid
Disturbances of sulphur-bearing amino-acid metabolism
 Endocrine/metabolic 0.893 0.605 – 1.32 0.569 29 348 exclusion phecode
270.2 Disorders of amino-acid metabolism Endocrine/metabolic 1.14 0.642 – 2.03 0.652 10 223 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.25 1.05 – 1.48 0.0107 164 1518 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.21 0.936 – 1.56 0.146 72 737 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 0.643 0.383 – 1.08 0.0954 19 142 exclusion phecode
270.34 Alpha-1-antitrypsin deficiency Endocrine/metabolic 0.833 0.48 – 1.45 0.517 18 134 exclusion phecode
270.38
Other specified disorders of plasma protein
Other specified disorders of plasma protein metabolism
 Endocrine/metabolic 1.41 1.09 – 1.82 0.00954 76 663 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.999 0.899 – 1.11 0.979 417 6296 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.988 0.886 – 1.1 0.821 394 6130 exclusion phecode
271.9
Other disorders of carbohydrate transport and
Other disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.31 0.853 – 2.02 0.217 26 230 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.03 0.983 – 1.09 0.199 2862 7532 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.03 0.982 – 1.09 0.206 2851 7518 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.02 0.942 – 1.1 0.663 885 5677 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.05 0.864 – 1.28 0.618 112 2933 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.02 0.915 – 1.14 0.72 426 4669 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.04 0.79 – 1.36 0.788 61 737 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.18 1.03 – 1.34 0.0138 266 4357 exclusion phecode
274.1 Gout Endocrine/metabolic 1.2 1.05 – 1.38 0.00922 232 4169 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.18 0.967 – 1.44 0.102 106 2021 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.949 0.674 – 1.34 0.765 44 379 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.973 0.691 – 1.37 0.877 43 358 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.25 1.16 – 1.34 6.64e-10 945 8233 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.991 0.658 – 1.49 0.965 27 469 exclusion phecode
275.11 Hereditary hemochromatosis Hematopoietic 1.21 0.533 – 2.73 0.653 7 203 exclusion phecode
275.2 Disorders of copper metabolism Endocrine/metabolic 1.11 0.63 – 1.94 0.727 15 153 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.46 1.28 – 1.67 3.18e-08 273 2426 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.21 1.12 – 1.32 1.8e-06 738 7005 exclusion phecode
275.51 Hypocalcemia Endocrine/metabolic 1.31 1.13 – 1.52 0.000307 218 1971 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.24 1.09 – 1.4 0.000849 320 2783 exclusion phecode
275.6 Hypercalcemia Endocrine/metabolic 1.28 1.12 – 1.45 0.000165 290 3120 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.25 1.19 – 1.32 2.15e-17 2041 8801 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.32 1.24 – 1.41 1.1e-18 1364 7723 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.27 1.03 – 1.55 0.0218 127 1035 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.34 1.23 – 1.47 1.35e-10 637 4587 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.37 1.26 – 1.5 4.13e-12 600 5079 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.39 1.25 – 1.54 8.46e-10 444 4590 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.26 1.14 – 1.4 1.24e-05 443 4136 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.27 1.13 – 1.42 4.36e-05 371 3556 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.35 1.1 – 1.65 0.0038 124 982 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.26 1.18 – 1.35 3.12e-12 1141 7954 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.46 1.27 – 1.69 2.13e-07 239 2587 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 0.898 0.598 – 1.35 0.606 24 289 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.15 1.06 – 1.24 0.001 701 8379 exclusion phecode
277.2
Other disorders of purine and pyrimidine
Other disorders of purine and pyrimidine metabolism
 Endocrine/metabolic 1.63 1.12 – 2.36 0.011 28 771 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.06 0.895 – 1.26 0.497 161 1518 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.935 0.783 – 1.12 0.463 143 2051 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.963 0.787 – 1.18 0.711 109 1709 exclusion phecode
277.7 Dysmetabolic syndrome X Endocrine/metabolic 2 1.27 – 3.17 0.00293 17 1926 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.29 1.19 – 1.4 1.52e-09 678 10325 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.58 1.36 – 1.85 5.91e-09 177 10321 exclusion phecode
278.11 Morbid obesity Endocrine/metabolic 1.82 1.34 – 2.47 0.000129 40 10260 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 1.22 0.856 – 1.72 0.275 31 1298 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.2 1.06 – 1.36 0.00314 307 7284 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.13 1.04 – 1.22 0.00272 806 6578 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.18 1.05 – 1.33 0.0061 328 2565 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.18 0.939 – 1.49 0.154 93 720 exclusion phecode
279.2 Autoimmune disease NEC Endocrine/metabolic 1.01 0.865 – 1.18 0.889 198 1809 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.03 0.962 – 1.1 0.419 1119 8305 exclusion phecode
279.8
Other specified disorders involving the immune
Other specified disorders involving the immune mechanism
 Endocrine/metabolic 1.06 0.894 – 1.26 0.501 171 1473 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.17 1.1 – 1.26 4.24e-06 1078 7054 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.18 1.1 – 1.27 2.21e-06 1043 7020 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.19 1.07 – 1.32 0.00163 408 3775 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.21 0.983 – 1.49 0.0721 116 1161 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.19 0.897 – 1.58 0.227 62 579 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.33 0.875 – 2.01 0.183 28 267 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.09 0.768 – 1.54 0.639 43 434 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.22 0.932 – 1.61 0.145 63 652 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.01 0.779 – 1.31 0.936 69 693 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 0.995 0.713 – 1.39 0.976 46 437 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.27 0.899 – 1.79 0.176 38 411 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.14 0.795 – 1.64 0.474 33 345 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.892 0.54 – 1.47 0.655 15 152 exclusion phecode
284 Aplastic anemia Hematopoietic 1.31 1.12 – 1.54 0.000863 181 1365 exclusion phecode
284.1 Pancytopenia Hematopoietic 1.31 1.1 – 1.56 0.00248 157 1208 exclusion phecode
285 Other anemias Hematopoietic 1.17 1.12 – 1.22 4.35e-11 2829 7835 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.19 1.1 – 1.29 1.26e-05 806 5912 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.4 1.27 – 1.54 7.35e-12 523 4091 exclusion phecode
285.21 Anemia in chronic kidney disease Hematopoietic 1.51 1.31 – 1.75 2.98e-08 221 1743 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.3 1.1 – 1.53 0.00179 182 1437 exclusion phecode
286 Coagulation defects Hematopoietic 1.11 1.02 – 1.2 0.0117 767 7586 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.798 0.59 – 1.08 0.142 50 594 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.612 0.372 – 1.01 0.0536 20 197 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.938 0.594 – 1.48 0.784 22 307 exclusion phecode
286.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants
 Hematopoietic 1.07 0.978 – 1.18 0.136 550 5391 exclusion phecode
286.3
Coagulation defects complicating pregnancy or
Coagulation defects complicating pregnancy or postpartum
 Hematopoietic 1.18 0.797 – 1.74 0.411 34 325 exclusion phecode
286.4 Acquired coagulation factor deficiency Hematopoietic 1.12 0.824 – 1.52 0.473 50 500 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.01 0.69 – 1.49 0.949 24 279 exclusion phecode
286.6 Defibrination syndrome Hematopoietic 1.04 0.94 – 1.14 0.476 491 5592 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.06 0.969 – 1.16 0.205 588 6545 exclusion phecode
286.8 Hypercoagulable state Hematopoietic 1.06 0.891 – 1.26 0.51 158 1963 exclusion phecode
286.81 Primary hypercoagulable state Hematopoietic 1.04 0.866 – 1.24 0.703 150 1863 exclusion phecode
286.9 Abnormal coagulation profile Hematopoietic 1.26 1.09 – 1.46 0.00169 224 2405 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.11 1.03 – 1.21 0.00783 740 6201 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.85 0.638 – 1.13 0.267 55 491 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.13 1.04 – 1.23 0.00313 671 5659 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.05 0.862 – 1.27 0.652 119 1303 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.19 0.98 – 1.44 0.0802 135 1209 exclusion phecode
287.4 Qualitative platelet defects Hematopoietic 1.1 0.7 – 1.72 0.684 23 267 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.15 1.07 – 1.22 3.35e-05 1201 8361 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.13 1.02 – 1.24 0.0139 515 3506 exclusion phecode
288.11 Neutropenia Hematopoietic 1.25 1.11 – 1.41 0.000292 341 2383 exclusion phecode
288.2 Elevated white blood cell count Hematopoietic 1.14 1.06 – 1.22 0.000368 962 7794 exclusion phecode
288.3 Eosinophilia Hematopoietic 0.897 0.649 – 1.24 0.509 46 411 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.14 1.03 – 1.27 0.0133 440 3991 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.08 0.935 – 1.25 0.294 232 2168 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.1 1.02 – 1.18 0.0102 946 7908 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1.27 1.01 – 1.61 0.0441 79 834 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.61 1.13 – 2.31 0.00929 40 463 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.46 1.17 – 1.83 0.000861 99 843 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.07 0.948 – 1.21 0.27 326 2192 exclusion phecode
290.1 Dementias Mental Disorders 0.895 0.731 – 1.09 0.28 116 945 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.945 0.636 – 1.4 0.78 32 269 exclusion phecode
290.12 Dementia with cerebral degenerations Mental Disorders 0.603 0.352 – 1.03 0.0646 15 151 exclusion phecode
290.13 Senile dementia Mental Disorders 0.885 0.687 – 1.14 0.344 75 604 exclusion phecode
290.16 Vascular dementia Mental Disorders 1.01 0.613 – 1.66 0.974 20 144 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.09 0.93 – 1.28 0.288 200 1357 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.981 0.846 – 1.14 0.798 208 1877 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.12 1.02 – 1.23 0.0192 540 5706 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.854 0.605 – 1.21 0.371 36 500 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.06 0.889 – 1.27 0.5 135 1160 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.15 1.03 – 1.28 0.0135 404 4403 exclusion phecode
292 Neurological disorders Mental Disorders 1.1 1.04 – 1.17 0.0017 1340 8914 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.11 1.01 – 1.23 0.0271 514 4104 exclusion phecode
292.11 Aphasia Mental Disorders 1 0.843 – 1.19 0.977 158 1414 exclusion phecode
292.12 Symbolic dysfunction Mental Disorders 0.848 0.621 – 1.16 0.298 45 448 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.958 0.764 – 1.2 0.713 83 779 exclusion phecode
292.3 Memory loss Mental Disorders 0.921 0.827 – 1.02 0.131 394 3874 exclusion phecode
292.4 Altered mental status Mental Disorders 1.22 1.11 – 1.34 3.08e-05 544 4644 exclusion phecode
292.5 Transient alteration of awareness Mental Disorders 1.05 0.852 – 1.3 0.634 105 944 exclusion phecode
292.6 Hallucinations Mental Disorders 1.37 1 – 1.88 0.0478 50 472 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.18 0.962 – 1.46 0.11 109 942 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.08 1.01 – 1.16 0.0214 1033 8730 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.17 1.01 – 1.36 0.0385 211 1890 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.03 0.715 – 1.47 0.886 30 327 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.28 0.823 – 2 0.272 24 252 exclusion phecode
295.3 Psychosis Mental Disorders 1.23 1.05 – 1.46 0.0124 175 1527 exclusion phecode
296 Mood disorders Mental Disorders 1.11 1.06 – 1.16 1.14e-05 3358 5135 exclusion phecode
296.1 Bipolar Mental Disorders 1.23 1.08 – 1.41 0.0016 288 3055 exclusion phecode
296.2 Depression Mental Disorders 1.1 1.05 – 1.16 4.35e-05 3217 5134 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.11 1.06 – 1.17 1.2e-05 2978 5134 exclusion phecode
297 Suicidal ideation or attempt Mental Disorders 1.2 1.05 – 1.37 0.00694 273 2462 exclusion phecode
297.1 Suicidal ideation Mental Disorders 1.15 0.99 – 1.34 0.0682 211 2001 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.26 1.01 – 1.56 0.0373 99 768 exclusion phecode
300 Anxiety disorders Mental Disorders 1.12 1.07 – 1.17 5.93e-07 3742 5135 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.13 1.08 – 1.19 1.12e-07 3556 5135 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 1.12 1.05 – 1.2 0.000497 1339 4978 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.07 0.94 – 1.21 0.317 330 3115 exclusion phecode
300.13 Phobia Mental Disorders 1.14 0.984 – 1.31 0.0826 243 2450 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.709 0.548 – 0.917 0.00879 75 881 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.15 1.05 – 1.26 0.00275 590 4164 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.14 0.913 – 1.43 0.243 103 1260 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.15 0.978 – 1.34 0.0916 192 2136 exclusion phecode
301 Personality disorders Mental Disorders 1.13 0.926 – 1.39 0.223 110 1340 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.12 0.855 – 1.46 0.417 64 700 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 0.957 0.869 – 1.05 0.366 544 2894 exclusion phecode
302.1 Decreased libido Mental Disorders 0.833 0.67 – 1.04 0.101 97 1003 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.923 0.867 – 0.982 0.011 1620 4752 exclusion phecode
303.1 Dissociative disorder Mental Disorders 1.14 0.784 – 1.66 0.49 32 423 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.918 0.862 – 0.978 0.0077 1550 4697 exclusion phecode
303.31
Gastrointestinal malfunction arising from
Gastrointestinal malfunction arising from mental factors
 Mental Disorders 0.822 0.672 – 1.01 0.0584 120 1144 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.999 0.881 – 1.13 0.988 312 3000 exclusion phecode
304 Adjustment reaction Mental Disorders 1.09 1.01 – 1.18 0.0203 930 4959 exclusion phecode
305.2 Eating disorder Mental Disorders 1.27 1.06 – 1.52 0.00865 145 2340 exclusion phecode
306 Other mental disorder Mental Disorders 1.04 0.935 – 1.15 0.49 464 3668 exclusion phecode
306.1 Mental disorders durring/after pregnancy Mental Disorders 1.08 0.898 – 1.29 0.424 156 1234 exclusion phecode
306.9 Tension headache Mental Disorders 0.944 0.805 – 1.11 0.481 189 2011 exclusion phecode
312 Conduct disorders Mental Disorders 1.11 0.852 – 1.44 0.447 74 661 exclusion phecode
312.3 Impulse control disorder Mental Disorders 0.821 0.515 – 1.31 0.405 23 218 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 1.08 0.976 – 1.19 0.14 467 4203 exclusion phecode
313.1 Attention deficit hyperactivity disorder Mental Disorders 1.08 0.976 – 1.2 0.132 423 3835 exclusion phecode
313.2 Tics and stuttering Mental Disorders 0.897 0.56 – 1.44 0.651 23 217 exclusion phecode
313.3 Autism Mental Disorders 0.817 0.469 – 1.42 0.475 12 202 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.04 0.877 – 1.23 0.657 167 1581 exclusion phecode
315.1 Learning disorder Mental Disorders 0.946 0.638 – 1.4 0.782 25 273 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.99 0.757 – 1.3 0.944 62 604 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.31 1.22 – 1.4 1.24e-13 963 7539 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.975 0.817 – 1.16 0.777 153 1360 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.24 1.14 – 1.35 4.73e-07 671 4789 exclusion phecode
317.1 Alcoholism Mental Disorders 1.26 1.15 – 1.38 1.41e-06 561 3801 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.16 0.911 – 1.47 0.229 81 651 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.34 1.27 – 1.41 6.31e-28 2004 8160 exclusion phecode
320 Meningitis Neurological 1.08 0.874 – 1.34 0.473 101 872 exclusion phecode
323 Encephalitis Neurological 1.31 0.957 – 1.79 0.0924 45 392 exclusion phecode
323.8 Encephalitis, non-infectious Neurological 1.27 0.896 – 1.81 0.178 39 330 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.07 0.802 – 1.43 0.641 52 626 exclusion phecode
325
Phlebitis and thrombophlebitis of intracranial
Phlebitis and thrombophlebitis of intracranial venous sinuses
 Neurological 1.09 0.529 – 2.26 0.808 10 118 exclusion phecode
327 Sleep disorders Neurological 1.05 1 – 1.11 0.0468 2171 8803 exclusion phecode
327.1 Hypersomnia Neurological 1.01 0.884 – 1.14 0.936 266 5126 exclusion phecode
327.3 Sleep apnea Neurological 0.985 0.916 – 1.06 0.679 898 8640 exclusion phecode
327.31 Central/nonobstroctive sleep apnea Neurological 1.04 0.827 – 1.3 0.744 81 1103 exclusion phecode
327.32 Obstructive sleep apnea Neurological 0.974 0.895 – 1.06 0.537 639 8241 exclusion phecode
327.4 Insomnia Neurological 1.07 1 – 1.14 0.0394 1270 8485 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.08 0.95 – 1.22 0.242 286 3274 exclusion phecode
327.5 Parasomnia Neurological 1.05 0.831 – 1.32 0.697 74 1455 exclusion phecode
327.6 Circadian rhythm sleep disorder Neurological 0.815 0.609 – 1.09 0.17 54 740 exclusion phecode
327.7 Sleep related movement disorders Neurological 1.04 0.915 – 1.17 0.58 304 4527 exclusion phecode
327.71 Restless legs syndrome Neurological 1.05 0.917 – 1.19 0.505 263 4037 exclusion phecode
327.72 Sleep related leg cramps Neurological 0.991 0.61 – 1.61 0.969 18 181 exclusion phecode
331 Other cerebral degenerations Neurological 1.15 0.975 – 1.36 0.0981 175 1452 exclusion phecode
331.1 Hydrocephalus Neurological 1.06 0.825 – 1.36 0.652 69 663 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.21 0.974 – 1.49 0.0857 105 817 exclusion phecode
332 Parkinson's disease Neurological 0.954 0.769 – 1.18 0.668 99 706 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.02 0.938 – 1.12 0.586 607 5909 exclusion phecode
333.1 Essential tremor Neurological 1.06 0.895 – 1.25 0.513 163 1443 exclusion phecode
333.2 Myoclonus Neurological 1.01 0.731 – 1.41 0.936 39 365 exclusion phecode
333.4 Torsion dystonia Neurological 0.967 0.788 – 1.19 0.752 113 785 exclusion phecode
333.8 Other degenerative diseases of the basal ganglia Neurological 0.711 0.464 – 1.09 0.117 29 168 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.09 0.941 – 1.26 0.252 223 2251 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.47 0.875 – 2.46 0.146 21 164 exclusion phecode
334.2 Anterior horn cell disease Neurological 1.28 0.823 – 2.01 0.27 25 213 exclusion phecode
334.21 Amyotrophic Lateral Sclerosis Neurological 1.26 0.708 – 2.24 0.432 17 119 exclusion phecode
335 Multiple sclerosis Neurological 1.08 0.878 – 1.34 0.451 101 931 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.11 0.954 – 1.3 0.174 203 1628 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.53 1.18 – 1.98 0.00128 73 560 exclusion phecode
338 Pain Neurological 1.1 1.06 – 1.15 1.55e-06 4506 6507 exclusion phecode
338.1 Acute pain Neurological 1.12 1.07 – 1.17 3.4e-07 3556 6458 exclusion phecode
338.2 Chronic pain Neurological 1.13 1.07 – 1.19 3.35e-06 2162 6474 exclusion phecode
339 Other headache syndromes Neurological 1.05 0.994 – 1.1 0.0845 2155 8099 exclusion phecode
340 Migraine Neurological 1.04 0.986 – 1.11 0.138 1690 7395 exclusion phecode
340.1 Migrain with aura Neurological 1.12 1.04 – 1.21 0.00191 915 6012 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.11 0.775 – 1.59 0.572 34 302 exclusion phecode
342 Hemiplegia Neurological 1.19 0.971 – 1.45 0.0942 110 966 exclusion phecode
343 Infantile cerebral palsy Neurological 1.25 0.845 – 1.84 0.267 25 246 exclusion phecode
344 Other paralytic syndromes Neurological 1.25 1.06 – 1.48 0.00789 171 1436 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.1 1.01 – 1.2 0.0246 654 5981 exclusion phecode
345.1 Epilepsy Neurological 0.985 0.842 – 1.15 0.855 194 1787 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1 0.755 – 1.33 0.988 57 582 exclusion phecode
345.12 Partial epilepsy Neurological 0.93 0.77 – 1.12 0.452 138 1235 exclusion phecode
345.3 Convulsions Neurological 1.12 1.02 – 1.22 0.0131 620 5634 exclusion phecode
346
Abnormal findings on study of brain and/or
Abnormal findings on study of brain and/or nervous system
 Neurological 0.913 0.657 – 1.27 0.589 40 423 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.07 0.95 – 1.2 0.274 338 3127 exclusion phecode
346.2
Nonspecific abnormal results of function study
Nonspecific abnormal results of function study of brain and central nervous system
 Neurological 0.919 0.62 – 1.36 0.672 28 262 exclusion phecode
346.3
Nonspecific abnormal findings in cerebrospinal
Nonspecific abnormal findings in cerebrospinal fluid
 Neurological 1.31 0.818 – 2.08 0.264 19 257 exclusion phecode
347 Cataplexy and narcolepsy Neurological 1.12 0.709 – 1.76 0.637 20 250 exclusion phecode
348 Other conditions of brain Neurological 1.14 1.02 – 1.26 0.0163 425 4047 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.07 0.924 – 1.23 0.372 215 2071 exclusion phecode
348.4 Cerebral cysts Neurological 0.896 0.67 – 1.2 0.457 53 566 exclusion phecode
348.7 Coma Neurological 1.28 0.971 – 1.69 0.08 57 529 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.35 1.15 – 1.58 0.000193 195 1750 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.05 0.953 – 1.15 0.344 532 5180 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.17 1.01 – 1.34 0.0335 234 2163 exclusion phecode
350 Abnormal movement Neurological 1.08 1.02 – 1.14 0.0109 1494 9072 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.1 1.02 – 1.19 0.0174 750 6804 exclusion phecode
350.2 Abnormality of gait Neurological 1.09 1.01 – 1.18 0.0322 815 6558 exclusion phecode
350.3 Lack of coordination Neurological 1.04 0.917 – 1.18 0.532 293 2332 exclusion phecode
350.5 Abnormal reflex Neurological 1.15 0.829 – 1.58 0.41 43 453 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.96 0.781 – 1.18 0.698 118 1103 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.06 1 – 1.13 0.0484 1352 8345 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.11 0.997 – 1.24 0.0575 379 4003 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.12 0.928 – 1.35 0.235 125 1317 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.1 0.929 – 1.3 0.276 161 1792 exclusion phecode
353 Nerve root and plexus disorders Neurological 1.11 1.03 – 1.19 0.0067 843 7874 exclusion phecode
353.1 Nerve plexus lesions Neurological 1.02 0.834 – 1.26 0.815 110 956 exclusion phecode
353.2 Nerve root lesions Neurological 1.15 0.758 – 1.74 0.515 24 257 exclusion phecode
355 Complex regional/central pain syndrome Neurological 1.08 0.901 – 1.31 0.391 131 1290 exclusion phecode
355.1 Chronic pain syndrome Neurological 1.29 1.1 – 1.51 0.00167 181 1965 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.15 1.03 – 1.28 0.0136 395 4283 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.12 1.02 – 1.22 0.0124 623 6312 exclusion phecode
358 Myoneural disorders Neurological 1.13 0.982 – 1.29 0.0878 248 2514 exclusion phecode
358.1 Myasthenia gravis Neurological 0.829 0.539 – 1.27 0.391 26 245 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.982 0.869 – 1.11 0.77 309 2559 exclusion phecode
359.1 Muscular dystrophies Neurological 0.983 0.57 – 1.69 0.95 22 153 exclusion phecode
359.2 Myopathy Neurological 0.976 0.862 – 1.1 0.699 294 2454 exclusion phecode
360 Disorders of the globe Sense Organs 0.959 0.657 – 1.4 0.826 30 266 exclusion phecode
360.2 Progressive myopia Sense Organs 0.687 0.408 – 1.15 0.156 19 128 exclusion phecode
361 Retinal detachments and defects Sense Organs 1 0.847 – 1.19 0.967 156 1427 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.907 0.686 – 1.2 0.492 65 551 exclusion phecode
362 Other retinal disorders Sense Organs 0.999 0.92 – 1.09 0.989 747 4729 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.91 0.818 – 1.01 0.0865 450 3086 exclusion phecode
362.21 Macular degeneration, dry Sense Organs 0.794 0.621 – 1.02 0.0658 89 722 exclusion phecode
362.22 Macular degeneration, wet Sense Organs 0.92 0.613 – 1.38 0.688 34 253 exclusion phecode
362.23 Cystoid macular degeneration of retina Sense Organs 0.911 0.725 – 1.14 0.424 88 800 exclusion phecode
362.26 Macular puckering of retina Sense Organs 0.864 0.732 – 1.02 0.0826 173 1667 exclusion phecode
362.27 Drusen (degenerative) of retina Sense Organs 1.02 0.823 – 1.25 0.881 114 930 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.917 0.82 – 1.03 0.133 403 2769 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.11 0.941 – 1.3 0.219 174 1727 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1.3 1.04 – 1.62 0.021 87 771 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.976 0.81 – 1.18 0.801 134 1199 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.956 0.77 – 1.19 0.684 97 793 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.07 0.793 – 1.45 0.655 50 491 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.11 0.834 – 1.47 0.481 62 476 exclusion phecode
362.9 Retinal edema Sense Organs 0.974 0.74 – 1.28 0.849 59 565 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.873 0.707 – 1.08 0.208 114 962 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.837 0.647 – 1.08 0.178 73 644 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.995 0.873 – 1.13 0.942 283 2369 exclusion phecode
364.1 Corneal opacity Sense Organs 0.897 0.721 – 1.11 0.326 104 821 exclusion phecode
364.2 Corneal edema Sense Organs 1.23 0.791 – 1.92 0.354 22 244 exclusion phecode
364.4 Corneal degenerations Sense Organs 1.02 0.836 – 1.24 0.851 118 907 exclusion phecode
364.41 Keratoconus Sense Organs 0.514 0.303 – 0.87 0.0131 21 155 exclusion phecode
364.5 Corneal dystrophy Sense Organs 1.04 0.846 – 1.29 0.69 106 998 exclusion phecode
364.51 Fuchs' dystrophy Sense Organs 1.15 0.865 – 1.54 0.331 60 530 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.691 0.415 – 1.15 0.156 17 188 exclusion phecode
365 Glaucoma Sense Organs 0.96 0.875 – 1.05 0.395 573 4343 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 1.01 0.85 – 1.2 0.9 166 1308 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.873 0.688 – 1.11 0.261 93 729 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.82 0.609 – 1.1 0.19 67 484 exclusion phecode
366 Cataract Sense Organs 1 0.94 – 1.06 0.99 1738 5909 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.929 0.698 – 1.24 0.611 56 430 exclusion phecode
366.2 Senile cataract Sense Organs 0.971 0.902 – 1.04 0.425 1076 5140 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.941 0.893 – 0.99 0.02 2073 8929 exclusion phecode
367.1 Myopia Sense Organs 0.907 0.85 – 0.967 0.00287 1236 8271 exclusion phecode
367.2 Astigmatism Sense Organs 0.907 0.844 – 0.975 0.00796 963 7507 exclusion phecode
367.8 Hypermetropia Sense Organs 0.934 0.842 – 1.04 0.197 439 4193 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.1 0.963 – 1.25 0.161 276 2785 exclusion phecode
368 Visual disturbances Sense Organs 1.02 0.963 – 1.09 0.45 1304 9189 exclusion phecode
368.1 Amblyopia Sense Organs 1.16 0.967 – 1.4 0.11 142 1495 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.02 0.891 – 1.17 0.773 257 2306 exclusion phecode
368.3 Anisometropia Sense Organs 0.851 0.638 – 1.13 0.272 57 494 exclusion phecode
368.4 Visual field defects Sense Organs 0.961 0.828 – 1.11 0.596 202 2398 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.965 0.84 – 1.11 0.609 246 2456 exclusion phecode
368.91 Psychophysical visual disturbances Sense Organs 1.06 0.69 – 1.62 0.8 30 248 exclusion phecode
369 Infection of the eye Sense Organs 0.903 0.834 – 0.977 0.0117 768 6955 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.853 0.696 – 1.04 0.124 126 1209 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.905 0.831 – 0.986 0.0228 653 6187 exclusion phecode
370 Keratitis Sense Organs 0.853 0.759 – 0.958 0.00721 363 3031 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.824 0.632 – 1.07 0.151 73 497 exclusion phecode
370.2 Superficial keratitis Sense Organs 0.845 0.699 – 1.02 0.0812 135 1226 exclusion phecode
370.3 Keratoconjunctivitis Sense Organs 0.967 0.817 – 1.14 0.699 170 1469 exclusion phecode
370.31 Keratoconjunctivitis sicca Sense Organs 0.874 0.645 – 1.18 0.383 51 429 exclusion phecode
371 Inflammation of the eye Sense Organs 0.957 0.893 – 1.03 0.209 1061 7190 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.02 0.839 – 1.24 0.85 126 1173 exclusion phecode
371.2 Conjunctivitis, noninfectious Sense Organs 1.04 0.899 – 1.21 0.568 208 2101 exclusion phecode
371.21 Allergic conjunctivitis Sense Organs 1.03 0.871 – 1.21 0.748 171 1761 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.934 0.864 – 1.01 0.0868 827 5881 exclusion phecode
371.33 Noninfectious dermatoses of eyelid Sense Organs 1 0.718 – 1.4 0.98 45 323 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.02 0.895 – 1.17 0.754 270 2280 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.927 0.85 – 1.01 0.0857 666 5197 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.825 0.666 – 1.02 0.077 104 867 exclusion phecode
374.2 Lagophthalmos Sense Organs 1.18 0.909 – 1.53 0.214 71 518 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.965 0.84 – 1.11 0.619 248 2311 exclusion phecode
374.6 Dermatochalasis Sense Organs 0.915 0.781 – 1.07 0.266 193 2010 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.982 0.911 – 1.06 0.648 897 5809 exclusion phecode
375.1 Dry eyes Sense Organs 0.986 0.916 – 1.06 0.717 970 5921 exclusion phecode
375.2 Epiphora Sense Organs 0.947 0.767 – 1.17 0.616 109 943 exclusion phecode
376 Disorders of the orbit Sense Organs 1.03 0.816 – 1.29 0.827 85 816 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.15 0.985 – 1.35 0.0768 187 2041 exclusion phecode
377.1 Optic atrophy Sense Organs 1.15 0.876 – 1.51 0.316 61 600 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.2 0.989 – 1.46 0.064 118 1325 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.12 0.989 – 1.26 0.0738 308 2832 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.08 0.927 – 1.26 0.326 195 1886 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.05 0.763 – 1.46 0.751 44 362 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.06 0.832 – 1.35 0.638 83 745 exclusion phecode
379 Other disorders of eye Sense Organs 0.967 0.903 – 1.04 0.346 1109 6488 exclusion phecode
379.1 Scleritis and episcleritis Sense Organs 0.778 0.554 – 1.09 0.147 45 414 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.954 0.879 – 1.03 0.252 783 4805 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.769 0.529 – 1.12 0.171 38 278 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.05 0.803 – 1.38 0.709 62 614 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.04 0.806 – 1.35 0.749 73 591 exclusion phecode
379.51 Pigmentary iris degeneration Sense Organs 0.658 0.369 – 1.17 0.154 18 138 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.908 0.792 – 1.04 0.166 268 2541 exclusion phecode
380 Disorders of external ear Sense Organs 0.946 0.86 – 1.04 0.25 533 4433 exclusion phecode
380.1 Otitis externa Sense Organs 0.894 0.79 – 1.01 0.0765 292 3392 exclusion phecode
380.4 Impacted cerumen Sense Organs 0.913 0.836 – 0.997 0.0438 622 5170 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.01 0.943 – 1.08 0.763 984 8885 exclusion phecode
381.1 Otitis media Sense Organs 1.04 0.959 – 1.13 0.337 692 7540 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.05 0.961 – 1.15 0.275 570 6551 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.922 0.833 – 1.02 0.118 456 4389 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.947 0.664 – 1.35 0.766 30 367 exclusion phecode
381.9 Otorrhea Sense Organs 1.34 1.05 – 1.72 0.0197 82 892 exclusion phecode
382 Otalgia Sense Organs 0.985 0.892 – 1.09 0.767 473 4795 exclusion phecode
383 Otosclerosis Sense Organs 1.14 0.808 – 1.61 0.458 33 289 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 0.968 0.797 – 1.18 0.743 126 1334 exclusion phecode
384.1 Myringitis Sense Organs 0.882 0.484 – 1.6 0.68 13 126 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 0.943 0.76 – 1.17 0.596 100 1050 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.919 0.754 – 1.12 0.401 115 1063 exclusion phecode
385.3 Cholesteatoma Sense Organs 0.916 0.722 – 1.16 0.466 77 704 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.892 0.642 – 1.24 0.496 42 313 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.947 0.848 – 1.06 0.331 389 4144 exclusion phecode
386.1 Meniere's disease Sense Organs 0.972 0.749 – 1.26 0.831 69 699 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.934 0.825 – 1.06 0.275 313 3465 exclusion phecode
386.21 Central origin vertigo Sense Organs 0.897 0.779 – 1.03 0.133 239 2681 exclusion phecode
386.3 Labyrinthitis Sense Organs 0.9 0.795 – 1.02 0.0961 305 3323 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.03 0.971 – 1.09 0.34 1533 8939 exclusion phecode
388 Other disorders of ear Sense Organs 1.07 0.929 – 1.23 0.348 235 2220 exclusion phecode
389 Hearing loss Sense Organs 1.01 0.956 – 1.07 0.728 1750 9108 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.97 0.899 – 1.05 0.424 866 6253 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.06 0.919 – 1.22 0.43 231 2287 exclusion phecode
389.3 Degenerative and vascular disorders of ear Sense Organs 1.13 0.797 – 1.59 0.5 45 353 exclusion phecode
389.4 Tinnitus Sense Organs 1 0.912 – 1.1 0.972 536 4740 exclusion phecode
389.5 Disorders of acoustic nerve Sense Organs 1.3 0.907 – 1.85 0.155 35 268 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.08 0.958 – 1.23 0.201 313 2691 exclusion phecode
394.1 Mitral valve stenosis and aortic valve stenosis Circulatory System 0.987 0.767 – 1.27 0.917 71 628 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.01 0.815 – 1.25 0.932 103 958 exclusion phecode
394.3 Aortic valve disease Circulatory System 0.948 0.636 – 1.41 0.792 25 304 exclusion phecode
394.4 Acute rheumatic heart disease Circulatory System 0.935 0.541 – 1.61 0.808 11 124 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.1 0.918 – 1.33 0.294 146 1151 exclusion phecode
395 Heart valve disorders Circulatory System 1.09 1.01 – 1.17 0.0324 885 6001 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.02 0.929 – 1.12 0.666 538 4304 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.19 1.06 – 1.34 0.00248 378 3214 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.07 0.872 – 1.3 0.532 121 1016 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.29 0.866 – 1.92 0.21 29 245 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.12 0.961 – 1.3 0.148 205 2036 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.07 0.996 – 1.14 0.0664 1089 7743 exclusion phecode
401 Hypertension Circulatory System 1.18 1.12 – 1.24 4.09e-11 3346 7626 exclusion phecode
401.1 Essential hypertension Circulatory System 1.18 1.12 – 1.23 1.14e-10 3302 7627 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.41 1.28 – 1.55 2.21e-12 559 4287 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.12 0.92 – 1.36 0.26 115 1846 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.47 1.32 – 1.63 1.69e-12 433 3799 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.35 1.22 – 1.49 4.32e-09 489 4747 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.2 1.13 – 1.28 2.22e-08 1399 6875 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.992 0.815 – 1.21 0.935 114 1634 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.23 1.12 – 1.35 1.51e-05 581 4475 exclusion phecode
411.3 Angina pectoris Circulatory System 1.16 1.03 – 1.3 0.0113 351 3742 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.2 1.12 – 1.28 3.33e-07 1170 6026 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.939 0.608 – 1.45 0.775 22 310 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.22 1.14 – 1.32 1.5e-07 935 5489 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.19 0.938 – 1.51 0.153 78 862 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.21 1.1 – 1.33 7.68e-05 537 4888 exclusion phecode
414.2 ASCVD Circulatory System 1.08 0.878 – 1.33 0.471 105 1390 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.19 1.09 – 1.3 0.000174 568 6409 exclusion phecode
415.1 Acute pulmonary heart disease Circulatory System 1.18 1.04 – 1.33 0.00843 307 4016 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.18 1.04 – 1.33 0.00927 306 3996 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.25 1.11 – 1.41 0.000252 325 3624 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.21 1.01 – 1.45 0.0401 141 1459 exclusion phecode
416 Cardiomegaly Circulatory System 1.26 1.08 – 1.45 0.00223 223 2598 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.06 1.01 – 1.11 0.0123 2663 8303 exclusion phecode
418.1 Precordial pain Circulatory System 1 0.876 – 1.14 1 257 2916 exclusion phecode
420 Carditis Circulatory System 1.04 0.924 – 1.17 0.507 325 3199 exclusion phecode
420.1 Myocarditis Circulatory System 1.2 0.716 – 1.99 0.495 16 212 exclusion phecode
420.2 Pericarditis Circulatory System 1.06 0.899 – 1.25 0.499 176 1693 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.1 0.813 – 1.5 0.524 43 368 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.14 0.719 – 1.79 0.586 21 235 exclusion phecode
420.3 Endocarditis Circulatory System 1.04 0.875 – 1.23 0.662 162 1555 exclusion phecode
425 Cardiomyopathy Circulatory System 1.18 1.05 – 1.32 0.00491 365 3873 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.16 1.04 – 1.3 0.0101 347 3682 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.988 0.666 – 1.47 0.952 30 393 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.27 0.859 – 1.89 0.228 26 421 exclusion phecode
425.2 Secondary/extrinsic cardiomyopathies Circulatory System 1.11 0.865 – 1.43 0.406 72 673 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 2 1.23 – 3.25 0.00507 24 212 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.12 1.07 – 1.19 1.43e-05 2393 6433 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.11 0.975 – 1.27 0.114 282 2269 exclusion phecode
426.21 First degree AV block Circulatory System 1.04 0.882 – 1.22 0.648 184 1698 exclusion phecode
426.22 Mobitz II AV block Circulatory System 1.6 0.839 – 3.05 0.153 11 121 exclusion phecode
426.23 Second degree AV block Circulatory System 1.23 0.876 – 1.72 0.234 41 380 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1.1 0.869 – 1.4 0.422 85 744 exclusion phecode
426.25 Other heart block Circulatory System 1.32 0.939 – 1.87 0.11 38 337 exclusion phecode
426.3 Bundle branch block Circulatory System 1.1 0.978 – 1.23 0.115 378 2927 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.04 0.906 – 1.2 0.549 235 2178 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.13 0.952 – 1.35 0.16 152 1610 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.995 0.66 – 1.5 0.981 24 216 exclusion phecode
426.7 Abnormal electrocardiogram [ECG] [EKG] Circulatory System 1.13 1.07 – 1.2 1.09e-05 2072 6305 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.25 1.04 – 1.51 0.0197 137 1431 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.12 0.988 – 1.27 0.0762 305 2302 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.2 1.02 – 1.4 0.0288 189 1569 exclusion phecode
426.92 Cardiac defibrillator in situ Circulatory System 1.19 1 – 1.41 0.0502 150 1374 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.05 1 – 1.1 0.032 3759 6569 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.09 0.985 – 1.2 0.0977 517 4083 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.04 0.927 – 1.17 0.505 360 3264 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.18 1.02 – 1.38 0.0268 212 1952 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.04 0.96 – 1.13 0.332 880 4073 exclusion phecode
427.21 Atrial fibrillation Circulatory System 1.03 0.946 – 1.12 0.517 850 3984 exclusion phecode
427.22 Atrial flutter Circulatory System 0.976 0.854 – 1.12 0.724 270 2103 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.09 1.03 – 1.15 0.00375 1873 6497 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.02 0.809 – 1.27 0.894 89 1045 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.04 0.722 – 1.49 0.848 31 405 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.01 0.789 – 1.3 0.914 76 797 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.03 0.97 – 1.1 0.316 1413 6465 exclusion phecode
427.6 Premature beats Circulatory System 0.948 0.854 – 1.05 0.317 451 3494 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1.02 0.85 – 1.22 0.83 144 1322 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.14 1.07 – 1.22 5.34e-05 1198 6476 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.08 0.917 – 1.28 0.349 174 1536 exclusion phecode
427.9 Palpitations Circulatory System 0.935 0.872 – 1 0.0599 1079 6085 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.22 1.12 – 1.33 4.76e-06 692 5011 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.21 1.11 – 1.33 2.74e-05 592 4695 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.27 1.15 – 1.39 7.38e-07 568 4489 exclusion phecode
428.3
Heart failure with reduced EF [Systolic or
Heart failure with reduced EF [Systolic or combined heart failure]
 Circulatory System 1.25 1.1 – 1.41 0.000446 312 2812 exclusion phecode
428.4
Heart failure with preserved EF [Diastolic
Heart failure with preserved EF [Diastolic heart failure]
 Circulatory System 1.27 1.09 – 1.47 0.00167 207 2667 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.08 1.03 – 1.13 0.00235 2642 8036 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.17 1.02 – 1.34 0.0243 243 2297 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.16 1.09 – 1.24 1.11e-05 1140 6729 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.06 1.01 – 1.11 0.0256 2144 7990 exclusion phecode
429.9 Cardiac complications, not elsewhere classified Circulatory System 1.22 1.01 – 1.47 0.0419 123 1402 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.05 0.898 – 1.24 0.516 183 1622 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.19 0.9 – 1.57 0.224 60 542 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.1 0.875 – 1.39 0.403 87 759 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.03 0.803 – 1.33 0.792 73 525 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.14 1.06 – 1.22 0.000245 1116 6795 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.15 1.04 – 1.29 0.00847 418 3096 exclusion phecode
433.11
Occlusion of cerebral arteries, with cerebral
Occlusion of cerebral arteries, with cerebral infarction
 Circulatory System 1.06 0.796 – 1.4 0.704 60 505 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 0.835 0.499 – 1.4 0.494 16 154 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.18 1.07 – 1.31 0.000923 482 4311 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.19 1.07 – 1.31 0.000785 467 4173 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.1 1.01 – 1.21 0.0388 558 4590 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.11 1.01 – 1.23 0.0386 483 4143 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.09 0.894 – 1.33 0.396 123 1079 exclusion phecode
433.6 Acute, but ill-defined cerebrovascular disease Circulatory System 1.13 0.89 – 1.44 0.309 76 904 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.12 0.937 – 1.35 0.208 139 1421 exclusion phecode
440 Atherosclerosis Circulatory System 1.16 1.05 – 1.29 0.00295 483 3834 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.07 0.804 – 1.43 0.63 53 473 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.08 0.949 – 1.22 0.252 289 2602 exclusion phecode
440.21
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with ulceration or gangrene
 Circulatory System 1.37 1.03 – 1.82 0.0292 57 444 exclusion phecode
440.22
Atherosclerosis of native arteries of the
Atherosclerosis of native arteries of the extremities with intermittent claudication
 Circulatory System 1.04 0.89 – 1.21 0.652 202 1833 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.17 0.984 – 1.4 0.0757 146 1519 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.18 0.985 – 1.42 0.0727 141 1086 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.01 0.775 – 1.32 0.937 64 493 exclusion phecode
441.2 Chronic vascular insufficiency of intestine Circulatory System 1.13 0.832 – 1.53 0.439 49 341 exclusion phecode
442 Other aneurysm Circulatory System 1.14 1.03 – 1.25 0.0082 538 4204 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.12 1 – 1.26 0.0451 359 3044 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.07 0.929 – 1.24 0.332 231 1842 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.02 0.682 – 1.52 0.931 26 331 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.32 0.899 – 1.95 0.155 26 317 exclusion phecode
442.4 Arterial dissection Circulatory System 0.983 0.712 – 1.36 0.918 41 360 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.24 0.986 – 1.56 0.0657 97 829 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.1 1.01 – 1.19 0.0257 751 5181 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 0.996 0.873 – 1.14 0.95 299 1780 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.73 1.1 – 2.72 0.0176 25 321 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.11 1.02 – 1.22 0.0166 633 4524 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.17 1.06 – 1.29 0.00223 470 3653 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.15 0.989 – 1.34 0.0689 205 1687 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.05 0.831 – 1.33 0.675 85 563 exclusion phecode
444.2 Embolism and thrombosis of abdominal aorta Circulatory System 0.951 0.657 – 1.38 0.789 33 254 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.07 0.865 – 1.32 0.542 112 996 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.863 0.583 – 1.28 0.461 29 233 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.15 0.671 – 1.96 0.615 17 155 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.03 0.798 – 1.33 0.812 74 611 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.15 1.04 – 1.26 0.00458 541 4593 exclusion phecode
447.1 Stricture of artery Circulatory System 1.16 0.955 – 1.4 0.137 127 1103 exclusion phecode
447.7 Aortic ectasia Circulatory System 1.16 0.952 – 1.42 0.141 110 1448 exclusion phecode
448 Disease of capillaries Circulatory System 0.829 0.736 – 0.933 0.00187 338 2641 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.09 0.983 – 1.21 0.102 431 4714 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.917 0.772 – 1.09 0.323 154 1664 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.993 0.699 – 1.41 0.969 39 565 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1.09 1.02 – 1.17 0.0175 915 7002 exclusion phecode
452.1 Iatrogenic pulmonary embolism and infarction Circulatory System 1.08 0.762 – 1.53 0.67 32 571 exclusion phecode
452.2 Deep vein thrombosis [DVT] Circulatory System 1.08 0.993 – 1.18 0.0718 596 6075 exclusion phecode
452.8 Postphlebitic syndrome Circulatory System 0.627 0.385 – 1.02 0.0615 21 348 exclusion phecode
453 Chronic venous hypertension Circulatory System 0.951 0.69 – 1.31 0.761 47 476 exclusion phecode
454 Varicose veins Circulatory System 1.04 0.956 – 1.14 0.336 608 5675 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1.05 0.95 – 1.15 0.359 514 4894 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.996 0.881 – 1.13 0.948 316 3463 exclusion phecode
455 Hemorrhoids Circulatory System 0.959 0.9 – 1.02 0.198 1282 6964 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.958 0.875 – 1.05 0.361 567 5684 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.09 0.973 – 1.22 0.136 364 3134 exclusion phecode
457.2
Encounter for long-term (current) use of
Encounter for long-term (current) use of antiplatelets/antithrombotics
 Circulatory System 1.14 0.858 – 1.52 0.36 55 598 exclusion phecode
457.3 Encounter for long-term (current) use of aspirin Circulatory System 1.08 0.963 – 1.22 0.183 336 2996 exclusion phecode
458 Hypotension Circulatory System 1.24 1.16 – 1.32 2.47e-10 1176 7346 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.2 1.06 – 1.36 0.00364 332 2790 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.24 1.08 – 1.43 0.00257 240 2177 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.25 1.16 – 1.34 3.81e-10 1063 7007 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.15 1.08 – 1.22 7.63e-06 1488 8249 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.17 0.997 – 1.37 0.0551 198 1796 exclusion phecode
459.7 Blood vessel replaced Circulatory System 1.25 1.09 – 1.42 0.00108 270 2697 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.12 1.05 – 1.2 0.000647 1216 7763 exclusion phecode
464 Acute sinusitis Respiratory 0.969 0.905 – 1.04 0.373 1058 7669 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.97 0.924 – 1.02 0.222 2314 8379 exclusion phecode
465.2 Acute pharyngitis Respiratory 0.948 0.892 – 1.01 0.0859 1387 7845 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.93 0.749 – 1.15 0.513 99 1091 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.969 0.875 – 1.07 0.549 447 4242 exclusion phecode
471 Nasal polyps Respiratory 0.909 0.753 – 1.1 0.316 128 1347 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.912 0.817 – 1.02 0.102 386 4089 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.12 1.03 – 1.21 0.00656 765 5620 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.19 0.668 – 2.12 0.554 15 141 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.11 0.926 – 1.33 0.26 152 1442 exclusion phecode
473.4 Voice disturbance Respiratory 1.13 1.04 – 1.24 0.00521 621 4837 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1.12 0.986 – 1.27 0.0812 289 2465 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.07 0.889 – 1.3 0.461 129 1165 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.12 0.97 – 1.29 0.122 220 2021 exclusion phecode
475 Chronic sinusitis Respiratory 1.04 0.972 – 1.12 0.238 987 6534 exclusion phecode
475.9 Postnasal drip Respiratory 1.01 0.859 – 1.18 0.949 196 1995 exclusion phecode
476 Allergic rhinitis Respiratory 0.986 0.942 – 1.03 0.565 2895 6585 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.18 1.04 – 1.34 0.0129 266 2574 exclusion phecode
478 Throat pain Respiratory 1.19 0.973 – 1.45 0.0908 120 1024 exclusion phecode
479 Other upper respiratory disease Respiratory 1.09 1.02 – 1.16 0.00797 1311 6567 exclusion phecode
480 Pneumonia Respiratory 1.13 1.06 – 1.2 0.000174 1287 8722 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.17 1.03 – 1.32 0.0145 309 2487 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.29 1.08 – 1.56 0.00607 139 1193 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.23 0.894 – 1.68 0.206 50 359 exclusion phecode
480.13 MRSA pneumonia Respiratory 1.51 0.909 – 2.5 0.111 20 272 exclusion phecode
480.2 Viral pneumonia Respiratory 1.35 0.973 – 1.88 0.0722 41 379 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.48 1.07 – 2.04 0.018 47 332 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.39 0.976 – 1.98 0.0681 39 297 exclusion phecode
481 Influenza Respiratory 1.04 0.917 – 1.18 0.544 298 3205 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.989 0.908 – 1.08 0.798 646 7069 exclusion phecode
495 Asthma Respiratory 1.1 1.04 – 1.16 0.000396 1770 8173 exclusion phecode
495.1 Chronic obstructive asthma Respiratory 1.23 0.949 – 1.58 0.119 66 857 exclusion phecode
495.11 Chronic obstructive asthma with exacerbation Respiratory 1.14 0.472 – 2.76 0.77 8 159 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.04 0.921 – 1.17 0.557 321 4419 exclusion phecode
496 Chronic airway obstruction Respiratory 1.34 1.25 – 1.43 3.29e-17 1192 6161 exclusion phecode
496.1 Emphysema Respiratory 1.41 1.28 – 1.55 1.13e-12 559 3825 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.43 1.32 – 1.54 5.19e-19 840 5653 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.46 1.35 – 1.59 6.53e-20 770 5285 exclusion phecode
496.3 Bronchiectasis Respiratory 1.14 0.965 – 1.35 0.123 170 1143 exclusion phecode
497 Bronchitis Respiratory 1.12 0.996 – 1.25 0.0579 365 4623 exclusion phecode
498 Acute bronchospasm Respiratory 1.32 1.06 – 1.64 0.012 97 1271 exclusion phecode
499 Cystic fibrosis Respiratory 1.07 0.797 – 1.45 0.642 57 408 exclusion phecode
500 Lung disease due to external agents Respiratory 1.38 1.12 – 1.69 0.0025 122 1106 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.69 1.01 – 2.85 0.0465 23 203 exclusion phecode
500.2 Pneumoconiosis Respiratory 1.6 0.73 – 3.52 0.24 10 121 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.39 1.17 – 1.66 0.000219 173 1183 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.01 0.856 – 1.2 0.88 165 1637 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.21 1.02 – 1.43 0.0275 164 1657 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.06 0.87 – 1.28 0.575 126 1197 exclusion phecode
504.1 Idiopathic fibrosing alveolitis Respiratory 0.976 0.744 – 1.28 0.859 66 623 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.07 0.948 – 1.2 0.281 342 3215 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.2 1.1 – 1.3 1.6e-05 701 5222 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.15 1.06 – 1.26 0.000992 659 5524 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.21 1.1 – 1.34 0.000153 475 4713 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.22 1.13 – 1.32 4.1e-07 808 6265 exclusion phecode
509.1 Respiratory failure Respiratory 1.36 1.22 – 1.52 2e-08 427 3812 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.2 1.04 – 1.37 0.00941 269 2349 exclusion phecode
509.3
Pulmonary insufficiency or respiratory failure
Pulmonary insufficiency or respiratory failure following trauma and surgery
 Respiratory 1.19 1.06 – 1.33 0.00246 385 3241 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.27 1.12 – 1.43 0.00015 317 3416 exclusion phecode
510 Other diseases of lung Respiratory 1.11 1.04 – 1.18 0.00228 1194 7846 exclusion phecode
510.2 Lung transplant Respiratory 1.31 0.947 – 1.8 0.103 51 373 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.11 1.07 – 1.16 4.78e-07 3890 7132 exclusion phecode
512.1 Wheezing Respiratory 1.27 1.09 – 1.46 0.00153 215 3292 exclusion phecode
512.2 Painful respiration Respiratory 1.15 1.04 – 1.26 0.00418 552 5258 exclusion phecode
512.3 Abnormal chest sounds Respiratory 1.18 0.91 – 1.52 0.214 73 608 exclusion phecode
512.7 Shortness of breath Respiratory 1.17 1.1 – 1.23 3.25e-08 1926 7104 exclusion phecode
512.8 Cough Respiratory 1.07 1.02 – 1.13 0.0115 2033 7127 exclusion phecode
512.9 Other dyspnea Respiratory 1.13 1.07 – 1.19 7.86e-06 1997 7106 exclusion phecode
513 Respiratory abnormalities Respiratory 1.13 1.08 – 1.19 2.21e-07 2470 8537 exclusion phecode
513.3 Hypoventilation Respiratory 1.12 0.933 – 1.35 0.221 128 1878 exclusion phecode
513.31 Apnea Respiratory 1.1 0.866 – 1.4 0.431 76 960 exclusion phecode
513.32 Orthopnea Respiratory 1.22 0.834 – 1.77 0.311 28 412 exclusion phecode
513.4 Hyperventilation Respiratory 1.34 1.06 – 1.68 0.013 94 1120 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.31 0.952 – 1.79 0.098 40 488 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.16 1.09 – 1.24 8.81e-06 1193 7434 exclusion phecode
514.1
Abnormal results of function study of pulmonary
Abnormal results of function study of pulmonary system
 Respiratory 0.841 0.629 – 1.13 0.246 52 543 exclusion phecode
514.2 Solitary pulmonary nodule Respiratory 1.16 1.07 – 1.26 0.000637 652 5644 exclusion phecode
516 Abnormal sputum Respiratory 1.19 1.01 – 1.4 0.0405 169 1494 exclusion phecode
516.1 Hemoptysis Respiratory 1.17 0.974 – 1.4 0.0933 137 1263 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.13 1.07 – 1.2 3.17e-05 1418 9074 exclusion phecode
519.1 Tracheostomy complications Respiratory 1.65 1.24 – 2.18 0.000529 64 431 exclusion phecode
519.2 Respiratory complications Respiratory 1.14 0.921 – 1.42 0.224 94 928 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.08 0.964 – 1.2 0.194 382 3472 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.17 1.09 – 1.25 7.56e-06 1037 7618 exclusion phecode
520 Disorders of tooth development Digestive 0.995 0.819 – 1.21 0.957 120 952 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.22 0.88 – 1.7 0.23 52 380 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.957 0.759 – 1.21 0.713 77 638 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.45 1.26 – 1.66 1.33e-07 250 1935 exclusion phecode
521.1 Dental caries Digestive 1.42 1.23 – 1.64 1.33e-06 234 1781 exclusion phecode
521.2 Dental abrasion, erosion and attrition Digestive 0.956 0.52 – 1.76 0.884 8 116 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.32 1.09 – 1.61 0.00541 111 1178 exclusion phecode
522.5 Periapical abscess Digestive 1.46 1.18 – 1.8 0.000541 95 1040 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.23 1.04 – 1.46 0.0149 163 1547 exclusion phecode
523.1 Gingivitis Digestive 1.05 0.739 – 1.49 0.788 38 340 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.43 1.11 – 1.84 0.00526 71 779 exclusion phecode
523.31 Acute periodontitis Digestive 1.37 1.05 – 1.8 0.0206 56 663 exclusion phecode
523.32 Chronic periodontitis Digestive 1.59 1.07 – 2.38 0.0231 30 246 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1 0.833 – 1.21 0.983 160 1055 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.973 0.781 – 1.21 0.81 110 683 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.33 1.17 – 1.51 1.7e-05 278 2423 exclusion phecode
525.1 Loss of teeth or edentulism Digestive 1.32 1.06 – 1.64 0.0118 105 894 exclusion phecode
526 Diseases of the jaws Digestive 1.05 0.969 – 1.13 0.255 817 6561 exclusion phecode
526.1 Cysts of the jaws Digestive 0.801 0.609 – 1.05 0.113 53 512 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.947 0.769 – 1.17 0.605 123 786 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 0.996 0.898 – 1.1 0.937 453 3884 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.973 0.868 – 1.09 0.637 371 3116 exclusion phecode
526.42 Arthralgia/ankylosis of temporomandibular joint Digestive 1.03 0.892 – 1.19 0.696 237 2005 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 1.4 1.12 – 1.75 0.00335 104 654 exclusion phecode
526.8 Exostosis of jaw Digestive 1.67 0.965 – 2.91 0.0665 21 98 exclusion phecode
526.9 Jaw disease NOS Digestive 1.13 0.95 – 1.33 0.172 173 1118 exclusion phecode
527 Diseases of the salivary glands Digestive 1.07 0.967 – 1.19 0.183 425 3834 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 0.919 0.544 – 1.55 0.751 14 141 exclusion phecode
527.2 Sialoadenitis Digestive 1.1 0.881 – 1.38 0.393 95 913 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.17 1.01 – 1.35 0.0358 226 1880 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.03 0.769 – 1.39 0.821 54 529 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.07 0.987 – 1.16 0.0988 751 5899 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.11 0.953 – 1.3 0.179 200 1559 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.19 0.878 – 1.62 0.259 51 490 exclusion phecode
528.12 Oral aphthae Digestive 0.925 0.716 – 1.2 0.552 69 559 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.71 1.32 – 2.23 5.32e-05 74 528 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.746 0.51 – 1.09 0.132 33 296 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.819 0.494 – 1.36 0.439 23 176 exclusion phecode
528.5 Diseases of lips Digestive 1 0.832 – 1.21 0.965 142 1063 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.09 0.764 – 1.57 0.624 34 277 exclusion phecode
528.7 Sialolithiasis Digestive 1.3 0.937 – 1.81 0.115 44 339 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.08 0.91 – 1.28 0.384 156 1409 exclusion phecode
529.1 Glossitis Digestive 1.23 0.83 – 1.81 0.306 30 268 exclusion phecode
529.6 Glossodynia Digestive 0.954 0.658 – 1.38 0.803 30 321 exclusion phecode
530 Diseases of esophagus Digestive 1.15 1.1 – 1.21 4.53e-10 3202 7330 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.15 1.1 – 1.2 2.93e-09 3046 7330 exclusion phecode
530.11 GERD Digestive 1.15 1.09 – 1.2 8.94e-09 2914 7329 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.19 0.946 – 1.51 0.136 84 907 exclusion phecode
530.13 Barrett's esophagus Digestive 1.37 1.12 – 1.68 0.00253 106 1472 exclusion phecode
530.14 Reflux esophagitis Digestive 1.2 1.07 – 1.35 0.00156 367 4224 exclusion phecode
530.15 Eosinophilic esophagitis Digestive 1.05 0.778 – 1.43 0.734 49 627 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.2 1 – 1.44 0.0461 137 1353 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1.24 1.07 – 1.43 0.00451 217 2006 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.18 0.975 – 1.42 0.089 131 1344 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.928 0.652 – 1.32 0.68 43 257 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 2.21 1.36 – 3.6 0.00139 22 185 exclusion phecode
530.9 Heartburn Digestive 1.19 1.05 – 1.34 0.00742 300 3782 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.2 1.09 – 1.33 0.000452 435 4455 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.15 0.913 – 1.46 0.231 81 733 exclusion phecode
531.2 Gastric ulcer Digestive 1.3 1.13 – 1.49 0.000162 247 2646 exclusion phecode
531.3 Duodenal ulcer Digestive 1.14 0.926 – 1.41 0.21 99 883 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.17 0.992 – 1.38 0.0622 180 1724 exclusion phecode
531.5 Gastrojejunal ulcer Digestive 1.12 0.782 – 1.6 0.543 38 323 exclusion phecode
532 Dysphagia Digestive 1.28 1.2 – 1.36 2.78e-14 1388 6859 exclusion phecode
535 Gastritis and duodenitis Digestive 1.07 0.982 – 1.17 0.123 611 6299 exclusion phecode
535.1 Acute gastritis Digestive 1.25 1.09 – 1.43 0.00127 238 2623 exclusion phecode
535.2 Atrophic gastritis Digestive 0.919 0.72 – 1.17 0.495 76 786 exclusion phecode
535.6 Duodenitis Digestive 0.869 0.666 – 1.13 0.3 67 710 exclusion phecode
535.8 Other specified gastritis Digestive 1.08 0.904 – 1.28 0.412 142 1439 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.02 0.899 – 1.15 0.785 294 2905 exclusion phecode
536 Disorders of function of stomach Digestive 1.14 1.05 – 1.23 0.00111 771 6521 exclusion phecode
536.3 Gastroparesis Digestive 1.25 1.06 – 1.48 0.00723 184 1584 exclusion phecode
536.7
Complications of gastrostomy, colostomy and
Complications of gastrostomy, colostomy and enterostomy
 Digestive 1.35 1.12 – 1.64 0.00181 137 858 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.11 1.01 – 1.22 0.028 544 4961 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.17 1.08 – 1.26 0.000167 746 6762 exclusion phecode
537.1 Lesions of stomach and duodenum Digestive 1.53 1.07 – 2.2 0.0194 34 309 exclusion phecode
539 Bariatric surgery Digestive 2.55 1.98 – 3.29 6.15e-13 73 3739 exclusion phecode
540 Appendiceal conditions Digestive 0.875 0.723 – 1.06 0.174 126 1222 exclusion phecode
540.1 Appendicitis Digestive 0.826 0.673 – 1.01 0.068 110 1037 exclusion phecode
540.11 Acute appendicitis Digestive 0.811 0.65 – 1.01 0.0638 95 855 exclusion phecode
550 Abdominal hernia Digestive 1.02 0.956 – 1.09 0.571 1207 8816 exclusion phecode
550.1 Inguinal hernia Digestive 0.914 0.824 – 1.01 0.0852 445 3017 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.1 0.997 – 1.22 0.0581 446 5737 exclusion phecode
550.3 Femoral hernia Digestive 0.84 0.609 – 1.16 0.289 51 272 exclusion phecode
550.4 Umbilical hernia Digestive 0.896 0.759 – 1.06 0.199 155 2658 exclusion phecode
550.5 Ventral hernia Digestive 1.12 0.997 – 1.26 0.0568 340 4744 exclusion phecode
550.6 Incisional hernia Digestive 1.19 1.02 – 1.4 0.0285 177 2826 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.17 1.06 – 1.3 0.00207 466 3704 exclusion phecode
555.1 Regional enteritis Digestive 1.3 1.15 – 1.47 3.06e-05 313 2269 exclusion phecode
555.2 Ulcerative colitis Digestive 1.06 0.931 – 1.21 0.365 273 2180 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1 0.849 – 1.19 0.963 175 1300 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.25 1.05 – 1.49 0.0106 159 1371 exclusion phecode
556.1 Ulceration of intestine Digestive 1.24 1.04 – 1.49 0.0188 139 1217 exclusion phecode
556.11
Angiodysplasia of intestine (without mention of
Angiodysplasia of intestine (without mention of hemorrhage)
 Digestive 1.25 0.899 – 1.75 0.183 40 393 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.19 1.07 – 1.33 0.00161 381 4374 exclusion phecode
557.1 Celiac disease Digestive 1.07 0.893 – 1.28 0.463 155 1065 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.17 1.09 – 1.26 3.05e-05 893 6442 exclusion phecode
559 Ileostomy status Digestive 1.22 1.06 – 1.4 0.00436 248 2053 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.22 1.13 – 1.32 8e-07 792 5625 exclusion phecode
560.1 Paralytic ileus Digestive 1.16 1.04 – 1.29 0.00999 385 3274 exclusion phecode
560.2 Impaction of intestine Digestive 1.35 1.09 – 1.67 0.00637 111 930 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.21 0.954 – 1.53 0.116 90 613 exclusion phecode
560.4 Other intestinal obstruction Digestive 1.26 1.14 – 1.4 5.64e-06 482 3597 exclusion phecode
561 Symptoms involving digestive system Digestive 1.11 1.02 – 1.21 0.0138 672 5257 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1.03 0.96 – 1.11 0.385 1035 4936 exclusion phecode
562.1 Diverticulosis Digestive 1.03 0.953 – 1.1 0.501 1026 4925 exclusion phecode
562.2 Diverticulitis Digestive 1.17 1.02 – 1.35 0.0225 249 3143 exclusion phecode
564 Functional digestive disorders Digestive 1.14 1.09 – 1.2 3.19e-08 2747 6964 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.12 1.04 – 1.21 0.0027 904 5634 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.19 1.09 – 1.29 5.8e-05 685 5931 exclusion phecode
565 Anal and rectal conditions Digestive 1.02 0.946 – 1.1 0.598 818 6940 exclusion phecode
565.1 Anal and rectal polyp Digestive 0.885 0.77 – 1.02 0.0854 236 2505 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.27 1.13 – 1.43 6.31e-05 336 2915 exclusion phecode
568 Other disorders of peritoneum Digestive 1.13 1.01 – 1.26 0.0341 372 3676 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.2 1.05 – 1.37 0.0082 262 2676 exclusion phecode
569 Other disorders of intestine Digestive 1.11 1.05 – 1.18 0.000164 1700 8326 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.23 0.956 – 1.59 0.107 81 697 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.24 1.09 – 1.4 0.000674 304 3101 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.19 1.1 – 1.29 2.75e-05 692 7454 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.18 1.08 – 1.28 0.00017 622 7333 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.25 1.06 – 1.46 0.00686 178 1964 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.49 1.06 – 2.09 0.0229 38 370 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.21 1.04 – 1.41 0.0155 201 1842 exclusion phecode
571.81 Portal hypertension Digestive 1.19 0.964 – 1.47 0.105 106 1127 exclusion phecode
572 Ascites (non malignant) Digestive 1.19 1.09 – 1.3 0.000178 575 5073 exclusion phecode
573 Other disorders of liver Digestive 1.12 1.04 – 1.2 0.00131 1049 7805 exclusion phecode
573.1 Chronic passive congestion of liver Digestive 1.69 1.12 – 2.55 0.0123 33 296 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.27 0.981 – 1.64 0.0702 71 550 exclusion phecode
573.3 Hepatomegaly Digestive 1.25 1 – 1.56 0.0479 93 1082 exclusion phecode
573.4 Acute and subacute necrosis of liver Digestive 1.21 0.942 – 1.56 0.136 80 635 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.25 1.09 – 1.44 0.00189 232 1937 exclusion phecode
573.6
Nonspecific elevation of levels of transaminase
Nonspecific elevation of levels of transaminase or lactic acid dehydrogenase [LDH]
 Digestive 1.15 1.05 – 1.26 0.00216 560 5842 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.13 1.04 – 1.24 0.00601 572 6092 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.15 1.07 – 1.23 0.000111 969 7954 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.16 1.06 – 1.28 0.00169 520 7209 exclusion phecode
574.1 Cholelithiasis Digestive 1.16 1.05 – 1.28 0.00432 455 6806 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.07 0.794 – 1.44 0.663 46 772 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.902 0.71 – 1.15 0.401 77 1290 exclusion phecode
574.2 Calculus of bile duct Digestive 1.07 0.901 – 1.28 0.43 161 1979 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.28 1.07 – 1.54 0.00693 137 1871 exclusion phecode
575 Other biliary tract disease Digestive 1.14 1.03 – 1.25 0.00966 496 5142 exclusion phecode
575.1 Cholangitis Digestive 1.28 1.04 – 1.59 0.0206 101 731 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.32 1.12 – 1.56 0.000953 173 1349 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.761 0.548 – 1.06 0.103 40 529 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.19 1.01 – 1.4 0.0352 170 2192 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.2 1.06 – 1.35 0.00504 302 2508 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.865 0.648 – 1.15 0.323 56 590 exclusion phecode
577 Diseases of pancreas Digestive 1.19 1.08 – 1.3 0.000231 554 4716 exclusion phecode
577.1 Acute pancreatitis Digestive 1.3 1.14 – 1.48 5.86e-05 285 2551 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.55 1.28 – 1.88 6.46e-06 138 982 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.14 0.945 – 1.36 0.174 158 1167 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.1 1.03 – 1.18 0.00554 1007 8632 exclusion phecode
578.1 Hematemesis Digestive 1.29 1.06 – 1.58 0.0114 117 1060 exclusion phecode
578.2 Blood in stool Digestive 1.12 1.02 – 1.22 0.0125 600 5938 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.06 0.957 – 1.16 0.283 476 5034 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.16 1.03 – 1.3 0.0135 349 3224 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.11 1.04 – 1.2 0.00243 975 7967 exclusion phecode
579.2 Splenomegaly Digestive 1.19 0.983 – 1.44 0.0749 121 1577 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.07 0.955 – 1.21 0.23 326 3092 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.28 1.14 – 1.45 4.09e-05 327 3423 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.38 1.1 – 1.74 0.00567 93 846 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.42 0.971 – 2.09 0.0702 30 314 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.78 1.09 – 2.91 0.0217 17 241 exclusion phecode
580.13 Acute glomerulonephritis, NOS Genitourinary 1.44 0.847 – 2.44 0.179 13 135 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.46 1.12 – 1.9 0.00546 71 621 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.14 0.832 – 1.57 0.409 37 466 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.35 1.18 – 1.55 1.19e-05 249 2607 exclusion phecode
580.31
Nephritis and nephropathy in diseases
Nephritis and nephropathy in diseases classified elsewhere
 Genitourinary 1.29 1.07 – 1.55 0.0065 138 1500 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.44 1.22 – 1.72 2.82e-05 147 1449 exclusion phecode
580.4 Renal sclerosis, NOS Genitourinary 1.23 0.961 – 1.56 0.101 71 754 exclusion phecode
585 Renal failure Genitourinary 1.26 1.18 – 1.34 3.91e-13 1352 7675 exclusion phecode
585.1 Acute renal failure Genitourinary 1.32 1.22 – 1.42 4.73e-12 803 6037 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.29 1.1 – 1.52 0.00193 182 1711 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.26 1.17 – 1.35 3.4e-10 985 6716 exclusion phecode
585.31 Renal dialysis Genitourinary 1.39 1.18 – 1.64 7.39e-05 176 1530 exclusion phecode
585.32 End stage renal disease Genitourinary 1.5 1.3 – 1.72 2.18e-08 238 2054 exclusion phecode
585.33 Chronic Kidney Disease, Stage III Genitourinary 1.27 1.15 – 1.4 2.53e-06 492 4489 exclusion phecode
585.34 Chronic Kidney Disease, Stage IV Genitourinary 1.34 1.15 – 1.57 0.000197 187 1901 exclusion phecode
585.4 Chronic kidney disease, Stage I or II Genitourinary 1.27 1.1 – 1.46 0.00128 232 2389 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.14 1.08 – 1.21 7.14e-06 1476 8474 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.16 0.924 – 1.45 0.202 86 891 exclusion phecode
586.11 Small kidney Genitourinary 1.15 0.846 – 1.55 0.38 45 515 exclusion phecode
586.12 Vesicoureteral reflux Genitourinary 1.04 0.761 – 1.41 0.818 40 401 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.08 0.949 – 1.24 0.236 257 2645 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.3 0.948 – 1.78 0.104 44 391 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.07 0.965 – 1.2 0.192 391 3829 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.4 1.21 – 1.61 4.41e-06 231 1742 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.44 1.24 – 1.66 1.12e-06 220 2000 exclusion phecode
588.1 Renal osteodystrophy Genitourinary 1.38 1.09 – 1.75 0.00718 85 582 exclusion phecode
588.2 Secondary hyperparathyroidism (of renal origin) Genitourinary 1.37 1.16 – 1.63 0.000295 155 1556 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.21 1.04 – 1.4 0.0139 210 2132 exclusion phecode
590 Pyelonephritis Genitourinary 1.11 0.986 – 1.25 0.0847 326 3559 exclusion phecode
591 Urinary tract infection Genitourinary 1.02 0.966 – 1.07 0.553 2300 7506 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.05 0.97 – 1.14 0.216 740 5943 exclusion phecode
592.1 Cystitis Genitourinary 1.06 0.977 – 1.16 0.157 698 5747 exclusion phecode
592.11 Acute cystitis Genitourinary 1.08 0.969 – 1.2 0.168 421 4051 exclusion phecode
592.12 Chronic cystitis Genitourinary 1.09 0.807 – 1.48 0.566 49 587 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.02 0.844 – 1.23 0.845 139 1166 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.07 0.812 – 1.4 0.639 62 490 exclusion phecode
593 Hematuria Genitourinary 1.01 0.945 – 1.09 0.703 970 7381 exclusion phecode
593.1 Gross hematuria Genitourinary 0.991 0.874 – 1.12 0.891 285 2873 exclusion phecode
593.2 Microscopic hematuria Genitourinary 1.02 0.885 – 1.18 0.754 229 2282 exclusion phecode
594 Urinary calculus Genitourinary 1.07 1 – 1.14 0.0398 1206 9137 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.06 0.991 – 1.13 0.0921 1117 9085 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.2 0.948 – 1.52 0.131 80 715 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.05 0.914 – 1.2 0.497 234 3001 exclusion phecode
594.8 Renal colic Genitourinary 1.19 0.922 – 1.54 0.181 70 882 exclusion phecode
595 Hydronephrosis Genitourinary 1.24 1.11 – 1.39 0.000168 382 3817 exclusion phecode
596 Other disorders of bladder Genitourinary 0.957 0.88 – 1.04 0.308 673 5962 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.05 0.828 – 1.34 0.673 75 680 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 0.973 0.871 – 1.09 0.63 381 3817 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.01 0.884 – 1.15 0.922 278 2509 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.907 0.752 – 1.09 0.308 129 1171 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.04 0.901 – 1.21 0.574 217 2148 exclusion phecode
597.8 Urethral hypermobility/ISD Genitourinary 1.16 0.833 – 1.61 0.382 40 454 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.55 0.979 – 2.45 0.0618 25 281 exclusion phecode
598.4 Other cells and casts in urine Genitourinary 1.4 0.882 – 2.23 0.153 23 247 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.986 0.942 – 1.03 0.543 3011 7568 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.857 0.708 – 1.04 0.115 132 1245 exclusion phecode
599.2 Retention of urine Genitourinary 1.01 0.941 – 1.08 0.793 1038 6664 exclusion phecode
599.3 Dysuria Genitourinary 0.975 0.91 – 1.04 0.473 1049 6736 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.964 0.897 – 1.04 0.326 972 6365 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 0.972 0.908 – 1.04 0.413 1105 6871 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.24 1.03 – 1.48 0.0233 142 1204 exclusion phecode
599.7 Urethral discharge Genitourinary 0.992 0.641 – 1.54 0.972 18 194 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 0.938 0.876 – 1 0.0672 1114 6590 exclusion phecode
599.9 Other abnormality of urination Genitourinary 0.908 0.832 – 0.991 0.0314 621 5727 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.896 0.81 – 0.992 0.034 641 1750 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 0.932 0.787 – 1.1 0.414 157 1631 exclusion phecode
601.1 Prostatitis Genitourinary 0.866 0.67 – 1.12 0.27 76 724 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.861 0.56 – 1.32 0.495 31 199 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1.14 0.583 – 2.21 0.707 12 142 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.934 0.725 – 1.2 0.599 61 681 exclusion phecode
601.4 Balanoposthitis Genitourinary 1.03 0.608 – 1.75 0.909 13 226 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.09 0.735 – 1.62 0.67 23 286 exclusion phecode
602 Other disorders of prostate Genitourinary 1.03 0.78 – 1.36 0.838 67 483 exclusion phecode
602.3 Dysplasia of prostate Genitourinary 1.23 0.651 – 2.34 0.519 15 93 exclusion phecode
603 Other disorders of testis Genitourinary 1.07 0.856 – 1.33 0.567 86 836 exclusion phecode
603.1 Hydrocele Genitourinary 1.02 0.762 – 1.37 0.892 47 521 exclusion phecode
603.2 Spermatocele Genitourinary 0.966 0.695 – 1.34 0.837 40 283 exclusion phecode
604 Disorders of penis Genitourinary 0.898 0.748 – 1.08 0.25 133 1209 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.37 0.857 – 2.18 0.189 16 263 exclusion phecode
604.3 Peyronie's disease Genitourinary 0.84 0.618 – 1.14 0.268 48 330 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.907 0.819 – 1 0.0594 496 2198 exclusion phecode
608 Other disorders of male genital organs Genitourinary 0.957 0.85 – 1.08 0.463 317 2629 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.963 0.769 – 1.21 0.746 77 860 exclusion phecode
609.1 Infertility, male Genitourinary 1.03 0.795 – 1.33 0.835 56 653 exclusion phecode
609.11 Azoospermia and oligospermia Genitourinary 1.39 0.865 – 2.25 0.173 14 230 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.741 0.492 – 1.12 0.152 24 295 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.891 0.829 – 0.956 0.00142 1103 4593 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.908 0.822 – 1 0.0608 506 3675 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 0.552 0.317 – 0.962 0.0362 19 147 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.881 0.815 – 0.953 0.00155 879 4543 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.927 0.828 – 1.04 0.194 390 3126 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.887 0.836 – 0.941 7.01e-05 1789 4939 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.857 0.804 – 0.914 2.72e-06 1489 4263 exclusion phecode
611.11 Mammographic microcalcification Genitourinary 0.84 0.746 – 0.946 0.00416 364 2535 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.899 0.837 – 0.964 0.00297 1089 4931 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.862 0.747 – 0.995 0.0427 232 2773 exclusion phecode
612.1 Galactorrhea Genitourinary 0.797 0.555 – 1.14 0.219 34 435 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.977 0.813 – 1.17 0.806 135 2033 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 0.518 0.345 – 0.777 0.00149 36 230 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.943 0.881 – 1.01 0.0921 1132 5978 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 0.914 0.771 – 1.08 0.301 152 1564 exclusion phecode
613.5 Mastodynia Genitourinary 1.05 0.952 – 1.16 0.316 489 4210 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.859 0.751 – 0.983 0.0268 269 2329 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 0.858 0.751 – 0.98 0.0244 273 2469 exclusion phecode
613.9 Breast disorder NOS Genitourinary 0.938 0.842 – 1.04 0.243 424 3595 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.982 0.916 – 1.05 0.614 1089 5485 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.03 0.811 – 1.32 0.783 84 897 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.955 0.794 – 1.15 0.629 140 1356 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.01 0.666 – 1.52 0.977 31 282 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.91 0.683 – 1.21 0.519 61 500 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.885 0.688 – 1.14 0.341 72 687 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.937 0.688 – 1.28 0.678 52 476 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.97 0.901 – 1.04 0.421 944 5450 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.96 0.743 – 1.24 0.752 71 767 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.969 0.896 – 1.05 0.439 820 5315 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.21 0.84 – 1.76 0.302 37 368 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.839 0.631 – 1.11 0.226 59 631 exclusion phecode
615 Endometriosis Genitourinary 1.05 0.949 – 1.17 0.326 433 3999 exclusion phecode
618 Genital prolapse Genitourinary 1 0.907 – 1.1 0.99 508 4723 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.964 0.856 – 1.09 0.548 345 3445 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.01 0.84 – 1.21 0.943 145 1379 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.975 0.751 – 1.27 0.847 73 757 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.08 0.867 – 1.33 0.51 103 1118 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1 0.944 – 1.06 0.962 1658 5216 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.951 0.844 – 1.07 0.404 344 3480 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 0.988 0.831 – 1.18 0.893 154 1622 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.963 0.81 – 1.15 0.675 163 1311 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.996 0.917 – 1.08 0.928 760 5121 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.05 0.933 – 1.19 0.395 326 3206 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1.07 0.877 – 1.3 0.509 118 1063 exclusion phecode
620.1 Dysplasia of cervix Genitourinary 0.904 0.687 – 1.19 0.469 57 513 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.736 0.568 – 0.954 0.0205 63 1163 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.843 0.75 – 0.947 0.00393 353 3805 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.831 0.726 – 0.951 0.00726 258 2965 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 0.879 0.718 – 1.08 0.213 123 1162 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1 0.864 – 1.16 0.989 220 2246 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 1.03 0.922 – 1.14 0.642 437 3600 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 1.03 0.78 – 1.36 0.835 55 525 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 1.17 0.742 – 1.86 0.494 28 159 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.925 0.828 – 1.03 0.173 388 3990 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.969 0.913 – 1.03 0.311 1668 4852 exclusion phecode
625.1 Dyspareunia Genitourinary 0.948 0.849 – 1.06 0.346 405 3480 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.949 0.892 – 1.01 0.0938 1676 4395 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.928 0.866 – 0.995 0.0355 1227 4097 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 1.05 0.924 – 1.19 0.455 304 2629 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 0.927 0.842 – 1.02 0.126 547 3486 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.927 0.842 – 1.02 0.125 552 3582 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.892 0.781 – 1.02 0.0936 278 2647 exclusion phecode
626.15 Infertility, female, associated with anovulation Genitourinary 0.857 0.696 – 1.05 0.146 108 1134 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.997 0.893 – 1.11 0.954 408 3005 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.947 0.754 – 1.19 0.642 99 955 exclusion phecode
626.8 Infertility, female Genitourinary 0.911 0.796 – 1.04 0.179 255 2068 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.909 0.848 – 0.975 0.00735 1243 3886 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 0.844 0.737 – 0.966 0.0139 277 2549 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.914 0.843 – 0.992 0.0318 834 3588 exclusion phecode
627.21 Symptomatic artificial menopause Genitourinary 0.735 0.508 – 1.06 0.102 40 402 exclusion phecode
627.22
Need for Hormone replacement therapy
Need for Hormone replacement therapy (postmenopausal)
 Genitourinary 0.793 0.642 – 0.979 0.0312 113 855 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.866 0.761 – 0.984 0.0277 314 2315 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 0.947 0.753 – 1.19 0.642 91 963 exclusion phecode
627.5 Premature menopause and other ovarian failure Genitourinary 0.951 0.776 – 1.17 0.633 118 838 exclusion phecode
628 Ovarian cyst Genitourinary 0.932 0.846 – 1.03 0.158 539 3925 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.04 0.907 – 1.2 0.556 244 2293 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.898 0.709 – 1.14 0.37 90 772 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.722 0.495 – 1.05 0.0908 30 347 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.913 0.776 – 1.08 0.276 183 1632 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.926 0.757 – 1.13 0.45 122 1112 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.92 0.729 – 1.16 0.486 88 909 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.96 0.853 – 1.08 0.504 351 2386 exclusion phecode
636.1 Threatened premature labor Pregnancy Complications 1.07 0.883 – 1.3 0.486 131 1173 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 1.02 0.804 – 1.29 0.892 92 869 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.911 0.756 – 1.1 0.328 132 1359 exclusion phecode
636.8 Cervical incompetence Pregnancy Complications 1.31 0.826 – 2.08 0.251 22 245 exclusion phecode
637
Short gestation; low birth weight; and fetal
Short gestation; low birth weight; and fetal growth retardation
 Pregnancy Complications 1.45 0.918 – 2.3 0.111 20 240 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.881 0.729 – 1.06 0.188 129 1768 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.943 0.722 – 1.23 0.668 66 885 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.99 0.765 – 1.28 0.941 71 800 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.829 0.583 – 1.18 0.298 35 368 exclusion phecode
644 Anemia during pregnancy Pregnancy Complications 1.08 0.832 – 1.4 0.566 69 747 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1 0.87 – 1.16 0.946 227 2138 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.17 0.906 – 1.51 0.229 75 655 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.904 0.685 – 1.19 0.476 63 712 exclusion phecode
647.3 Major puerperal infection Pregnancy Complications 0.933 0.563 – 1.55 0.789 20 204 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.989 0.879 – 1.11 0.847 367 2532 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.901 0.74 – 1.1 0.299 124 1610 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1 0.845 – 1.19 0.972 163 1713 exclusion phecode
654.1
Abnormality of organs and soft tissues of
Abnormality of organs and soft tissues of pelvis complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.97 0.727 – 1.29 0.834 54 637 exclusion phecode
654.2 Rhesus isoimmunization in pregnancy Pregnancy Complications 0.776 0.593 – 1.02 0.0662 65 637 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.945 0.855 – 1.04 0.266 514 3055 exclusion phecode
655.1 Abnormality in fetal heart rate or rhythm Pregnancy Complications 0.93 0.79 – 1.09 0.379 188 1757 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.993 0.866 – 1.14 0.921 253 2170 exclusion phecode
656.2 Respiratory conditions of fetus and newborn Pregnancy Complications 1.1 0.54 – 2.24 0.792 5 144 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.94 0.821 – 1.08 0.371 266 2143 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.17 0.882 – 1.55 0.278 64 707 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.922 0.664 – 1.28 0.627 44 543 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.723 0.548 – 0.953 0.0216 63 580 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.16 1.1 – 1.24 9.21e-07 1331 9223 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.02 0.892 – 1.16 0.792 259 2612 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.26 1.09 – 1.46 0.00162 224 2219 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.22 1.09 – 1.36 0.000399 397 4472 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.17 1.06 – 1.31 0.00305 406 4641 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.25 1.11 – 1.41 0.000234 330 3685 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.15 1.02 – 1.31 0.0268 285 3560 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.09 0.986 – 1.2 0.0923 485 4893 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1 0.82 – 1.22 0.998 114 1391 exclusion phecode
686.2 Impetigo Dermatologic 1.16 0.927 – 1.44 0.196 102 1017 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.27 0.866 – 1.87 0.219 28 403 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.07 0.742 – 1.54 0.718 34 380 exclusion phecode
686.5 Pyoderma Dermatologic 2 0.944 – 4.23 0.0703 8 144 exclusion phecode
687 Symptoms affecting skin Dermatologic 0.942 0.848 – 1.04 0.257 449 3752 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.989 0.935 – 1.05 0.706 1623 8190 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.967 0.76 – 1.23 0.785 85 837 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.04 0.974 – 1.1 0.264 1359 8010 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.922 0.877 – 0.969 0.00138 2241 8716 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.893 0.836 – 0.954 0.000777 1200 6764 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.892 0.835 – 0.953 0.000727 1200 6752 exclusion phecode
691 Congenital anomalies of skin Dermatologic 1.02 0.844 – 1.24 0.831 123 1322 exclusion phecode
691.3 Congenital pigmentary anomalies of skin Dermatologic 1.44 0.89 – 2.33 0.137 21 163 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.868 0.787 – 0.958 0.00483 500 4084 exclusion phecode
694.1 Vitiligo Dermatologic 1.14 0.789 – 1.65 0.481 37 300 exclusion phecode
694.2 Other dyschromia Dermatologic 0.854 0.77 – 0.948 0.00293 447 3711 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.12 0.69 – 1.81 0.649 24 163 exclusion phecode
695 Erythematous conditions Dermatologic 0.978 0.906 – 1.06 0.565 844 6904 exclusion phecode
695.1 Toxic erythema Dermatologic 0.991 0.572 – 1.72 0.976 15 173 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.06 0.616 – 1.82 0.837 20 172 exclusion phecode
695.3 Rosacea Dermatologic 0.841 0.752 – 0.941 0.0026 366 3953 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.14 0.97 – 1.35 0.111 185 1711 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.17 0.89 – 1.53 0.263 67 616 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.13 0.958 – 1.34 0.143 177 1613 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 1.07 0.879 – 1.31 0.485 113 1324 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 0.982 0.802 – 1.2 0.857 105 1866 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.85 0.505 – 1.43 0.54 15 165 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.08 0.895 – 1.29 0.438 132 1504 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.944 0.83 – 1.07 0.383 275 3123 exclusion phecode
696.3 Pityriasis Dermatologic 0.757 0.518 – 1.11 0.152 36 277 exclusion phecode
696.4 Psoriasis Dermatologic 0.988 0.86 – 1.13 0.866 238 2876 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.97 0.841 – 1.12 0.674 222 2603 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.836 0.6 – 1.16 0.288 41 615 exclusion phecode
697 Sarcoidosis Dermatologic 1.29 0.95 – 1.75 0.103 47 653 exclusion phecode
698 Pruritus and related conditions Dermatologic 0.955 0.871 – 1.05 0.323 557 5421 exclusion phecode
700 Corns and callosities Dermatologic 0.948 0.822 – 1.09 0.465 229 2355 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.95 0.9 – 1 0.0696 1735 9024 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.993 0.823 – 1.2 0.943 141 1181 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.984 0.902 – 1.07 0.719 623 5144 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.982 0.811 – 1.19 0.851 133 1404 exclusion phecode
701.4 Keloid scar Dermatologic 0.934 0.786 – 1.11 0.435 158 1531 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1.08 0.859 – 1.35 0.523 91 904 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.868 0.817 – 0.923 4.84e-06 1588 6196 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.828 0.768 – 0.892 7.61e-07 950 5238 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.872 0.817 – 0.931 4.02e-05 1277 6486 exclusion phecode
702.4 Degenerative skin disorders Dermatologic 1.24 0.773 – 2 0.37 25 197 exclusion phecode
703 Diseases of nail, NOS Dermatologic 0.94 0.834 – 1.06 0.307 333 3307 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.956 0.81 – 1.13 0.596 167 1978 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.948 0.876 – 1.03 0.182 765 7325 exclusion phecode
704.1 Alopecia Dermatologic 0.888 0.797 – 0.989 0.0313 409 3630 exclusion phecode
704.11 Alopecia Areata Dermatologic 1.15 0.71 – 1.86 0.573 21 179 exclusion phecode
704.12 Telogen effluvium Dermatologic 0.949 0.584 – 1.54 0.834 22 160 exclusion phecode
704.2 Hirsutism Dermatologic 1.1 0.816 – 1.49 0.522 45 882 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.01 0.906 – 1.13 0.818 375 3901 exclusion phecode
705 Disorders of sweat glands Dermatologic 0.992 0.819 – 1.2 0.936 115 1541 exclusion phecode
705.1 Dyshidrosis Dermatologic 0.812 0.551 – 1.2 0.296 33 340 exclusion phecode
705.3 Hidradenitis Dermatologic 1.08 0.774 – 1.52 0.64 33 639 exclusion phecode
705.8 Hyperhidrosis Dermatologic 0.983 0.86 – 1.12 0.796 263 2649 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 0.883 0.834 – 0.935 2.01e-05 1531 9248 exclusion phecode
706.1 Acne Dermatologic 0.847 0.785 – 0.914 1.96e-05 832 5978 exclusion phecode
706.2 Sebaceous cyst Dermatologic 0.916 0.841 – 0.997 0.0434 644 6019 exclusion phecode
706.3 Seborrhea Dermatologic 0.646 0.381 – 1.1 0.106 16 137 exclusion phecode
706.8 Other specified diseases of sebaceous glands Dermatologic 0.908 0.803 – 1.03 0.122 322 3244 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.2 1.1 – 1.31 4.22e-05 597 5738 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.27 1.09 – 1.47 0.00233 206 1652 exclusion phecode
707.2 Chronic ulcer of leg or foot Dermatologic 1.27 1.08 – 1.49 0.00399 180 1928 exclusion phecode
707.3 Chronic ulcer of unspecified site Dermatologic 1.18 1.06 – 1.33 0.00334 356 3547 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.979 0.877 – 1.09 0.713 383 3529 exclusion phecode
709.2 Sicca syndrome Dermatologic 0.973 0.808 – 1.17 0.772 132 1192 exclusion phecode
709.3 Systemic sclerosis Dermatologic 0.945 0.737 – 1.21 0.659 72 515 exclusion phecode
709.5 Dermatomyositis Dermatologic 0.822 0.526 – 1.28 0.389 18 210 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.08 0.712 – 1.64 0.714 27 213 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.02 0.887 – 1.18 0.758 239 2277 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.25 1.1 – 1.42 0.00083 282 2616 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.25 1.09 – 1.42 0.00102 275 2462 exclusion phecode
710.11 Acute osteomyelitis Musculoskeletal 1.37 1.13 – 1.66 0.00133 130 1196 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.24 1.02 – 1.5 0.0341 126 1049 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.29 1.12 – 1.47 0.00025 258 2362 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 0.877 0.685 – 1.12 0.3 77 883 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.04 0.762 – 1.43 0.787 46 610 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.11 0.777 – 1.57 0.578 31 400 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.14 0.866 – 1.5 0.353 62 642 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.6 0.993 – 2.57 0.0537 20 304 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.14 1.03 – 1.26 0.0126 468 4438 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.21 1.08 – 1.35 0.00131 386 3663 exclusion phecode
714.2 Juvenile rheumatoid arthritis Musculoskeletal 1.04 0.717 – 1.51 0.836 33 237 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.06 0.921 – 1.22 0.423 244 2802 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.16 0.872 – 1.54 0.312 57 676 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.02 0.765 – 1.37 0.878 50 545 exclusion phecode
716 Other arthropathies Musculoskeletal 1.05 0.997 – 1.1 0.0656 2506 7939 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.898 0.626 – 1.29 0.56 33 432 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.907 0.571 – 1.44 0.678 20 272 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.05 0.997 – 1.1 0.0653 2492 7936 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.01 0.746 – 1.36 0.959 52 562 exclusion phecode
720 Spinal stenosis Musculoskeletal 1.08 0.995 – 1.18 0.0634 649 6151 exclusion phecode
720.1 Spinal stenosis of lumbar region Musculoskeletal 1.11 1 – 1.23 0.0465 428 4881 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1.09 1.02 – 1.17 0.0113 1075 7226 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.1 1.02 – 1.18 0.00999 1008 7068 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.16 0.972 – 1.37 0.102 152 1737 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 0.988 0.706 – 1.38 0.944 40 562 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.1 1.03 – 1.17 0.00362 1199 8037 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.13 1.03 – 1.22 0.00568 659 7186 exclusion phecode
722.3 Schmorl's nodes Musculoskeletal 1.12 0.768 – 1.64 0.554 32 264 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.11 1.02 – 1.2 0.0109 752 6798 exclusion phecode
722.7 Intervertebral disc disorder with myelopathy Musculoskeletal 1.24 0.988 – 1.56 0.0631 92 1084 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.22 0.949 – 1.57 0.12 73 827 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.996 0.889 – 1.12 0.942 370 4256 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.07 0.925 – 1.23 0.376 230 2233 exclusion phecode
723.1 Torticollis Musculoskeletal 1.13 0.861 – 1.49 0.376 62 589 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.02 0.952 – 1.1 0.515 890 7601 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1.03 0.936 – 1.13 0.542 520 5376 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.916 0.74 – 1.13 0.417 98 1021 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.07 0.91 – 1.25 0.426 175 2182 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.09 0.958 – 1.23 0.197 288 3198 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.961 0.912 – 1.01 0.125 2111 7342 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.963 0.91 – 1.02 0.203 1605 7313 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.931 0.791 – 1.1 0.393 173 2098 exclusion phecode
726.3 Bursitis Musculoskeletal 0.841 0.75 – 0.944 0.00321 359 3818 exclusion phecode
726.4 Calcaneal spur; Exostosis NOS Musculoskeletal 0.888 0.77 – 1.02 0.103 228 2653 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.982 0.927 – 1.04 0.547 1618 7309 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.01 0.925 – 1.1 0.869 681 6062 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.95 0.741 – 1.22 0.688 80 907 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.978 0.871 – 1.1 0.712 347 3217 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 1.04 0.826 – 1.31 0.732 89 1092 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.932 0.839 – 1.04 0.191 420 4585 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.07 0.905 – 1.26 0.433 167 1482 exclusion phecode
727.8 Plica syndrome Musculoskeletal 0.785 0.575 – 1.07 0.128 50 385 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.987 0.92 – 1.06 0.723 988 7020 exclusion phecode
728.1 Muscular calcification and ossification Musculoskeletal 1.35 0.841 – 2.17 0.213 22 186 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.04 0.818 – 1.31 0.766 77 712 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.89 0.806 – 0.982 0.0199 473 5331 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.705 0.57 – 0.872 0.00126 108 781 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.13 1.04 – 1.23 0.00564 669 6222 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.41 0.88 – 2.26 0.153 19 168 exclusion phecode
729.3 Panniculitis Musculoskeletal 1.18 0.636 – 2.19 0.599 9 304 exclusion phecode
729.7 Nontraumatic compartment syndrome Musculoskeletal 0.957 0.602 – 1.52 0.853 21 155 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.35 0.947 – 1.91 0.0978 36 353 exclusion phecode
732 Osteochondropathies Musculoskeletal 1.01 0.811 – 1.26 0.926 91 1000 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.998 0.71 – 1.4 0.991 40 530 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.15 0.734 – 1.81 0.539 24 265 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.975 0.913 – 1.04 0.462 1259 6039 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.09 0.81 – 1.47 0.563 53 452 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.17 0.979 – 1.39 0.0857 160 1061 exclusion phecode
733.6 Costochondritis Musculoskeletal 0.992 0.782 – 1.26 0.947 79 878 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.33 1.15 – 1.55 0.000176 207 1900 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.34 0.915 – 1.96 0.133 33 261 exclusion phecode
735 Acquired foot deformities Musculoskeletal 0.929 0.858 – 1.01 0.0676 762 6663 exclusion phecode
735.1 Flat foot Musculoskeletal 0.849 0.694 – 1.04 0.113 109 1399 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 0.943 0.826 – 1.08 0.383 279 2535 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.03 0.864 – 1.23 0.738 160 1562 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.954 0.766 – 1.19 0.671 103 848 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.841 0.748 – 0.947 0.00407 348 3312 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 0.936 0.857 – 1.02 0.141 614 6048 exclusion phecode
736.1 Acquired deformities of forearm Musculoskeletal 0.9 0.61 – 1.33 0.594 32 220 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.06 0.811 – 1.4 0.655 66 463 exclusion phecode
736.3 Acquired deformities of hip Musculoskeletal 0.86 0.491 – 1.51 0.599 16 188 exclusion phecode
736.4 Genu valgum or varum (acquired) Musculoskeletal 1.15 0.855 – 1.54 0.358 48 682 exclusion phecode
736.5 Acquired deformities of knee Musculoskeletal 1 0.71 – 1.41 0.998 32 499 exclusion phecode
736.6 Unequal leg length (acquired) Musculoskeletal 0.884 0.69 – 1.13 0.327 78 779 exclusion phecode
737 Curvature of spine Musculoskeletal 0.997 0.901 – 1.1 0.962 462 3890 exclusion phecode
737.1 Kyphosis (acquired) Musculoskeletal 1.11 0.901 – 1.36 0.332 110 1080 exclusion phecode
737.2 Lordosis (acquired) Musculoskeletal 1.69 0.94 – 3.04 0.0794 12 152 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.961 0.861 – 1.07 0.488 386 3060 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.15 1.05 – 1.25 0.00201 631 5535 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.21 1.04 – 1.41 0.0131 198 2157 exclusion phecode
739 Contracture of joint Musculoskeletal 1.03 0.863 – 1.23 0.732 160 1370 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.05 1 – 1.1 0.0454 2937 7929 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.988 0.922 – 1.06 0.727 1157 6673 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.982 0.914 – 1.06 0.631 1023 6187 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.05 0.866 – 1.27 0.626 122 1668 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.06 0.933 – 1.21 0.368 306 2887 exclusion phecode
740.3
Osteoarthrosis involving more than one site
Osteoarthrosis involving more than one site, but not specified as generalized
 Musculoskeletal 1.18 0.918 – 1.52 0.196 71 857 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.05 1 – 1.11 0.0326 2783 7867 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.999 0.948 – 1.05 0.979 1879 8544 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.923 0.698 – 1.22 0.575 54 599 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.03 0.912 – 1.16 0.637 323 2891 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 1.08 0.978 – 1.19 0.132 496 4936 exclusion phecode
741.4 Joint effusions Musculoskeletal 0.989 0.902 – 1.08 0.807 540 5845 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 0.82 0.499 – 1.35 0.435 18 199 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 1.15 0.598 – 2.23 0.669 11 169 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.985 0.92 – 1.05 0.664 1043 8142 exclusion phecode
742.1 Loose body in joint Musculoskeletal 1.03 0.711 – 1.49 0.881 28 422 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.951 0.758 – 1.19 0.663 85 933 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.16 0.897 – 1.51 0.252 62 634 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.982 0.916 – 1.05 0.612 985 8034 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.03 0.981 – 1.08 0.229 2537 8248 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.06 0.989 – 1.14 0.0986 1230 3995 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.06 0.985 – 1.14 0.118 1217 3952 exclusion phecode
743.12 Senile osteoporosis Musculoskeletal 1.01 0.877 – 1.16 0.892 292 1134 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1.15 0.912 – 1.45 0.24 109 601 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.04 0.922 – 1.18 0.491 326 2028 exclusion phecode
743.21 Pathologic fracture of vertebrae Musculoskeletal 1.06 0.879 – 1.29 0.523 131 862 exclusion phecode
743.22 Pathologic fracture of femur Musculoskeletal 1.51 1.06 – 2.15 0.0224 43 267 exclusion phecode
743.4 Stress fracture Musculoskeletal 0.843 0.69 – 1.03 0.0939 120 924 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.02 0.963 – 1.08 0.508 1853 7744 exclusion phecode
745 Pain in joint Musculoskeletal 0.972 0.934 – 1.01 0.164 4517 6498 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.02 0.931 – 1.12 0.638 525 4965 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.07 0.963 – 1.19 0.202 389 3920 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1.04 0.885 – 1.23 0.616 170 1512 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.16 0.964 – 1.4 0.115 128 1550 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.03 0.826 – 1.28 0.802 88 884 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.942 0.788 – 1.13 0.508 140 1163 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.22 0.81 – 1.83 0.343 29 272 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.918 0.785 – 1.07 0.286 206 1544 exclusion phecode
749.1 Cleft palate Congenital Anomalies 0.808 0.582 – 1.12 0.202 43 310 exclusion phecode
749.2 Congenital anomalies of skull and face bones Congenital Anomalies 0.976 0.698 – 1.37 0.889 46 303 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 1.17 1.02 – 1.34 0.0247 261 2050 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1 0.796 – 1.26 0.986 88 858 exclusion phecode
750.11 Esophageal atresia/tracheoesophageal fistula Congenital Anomalies 0.977 0.649 – 1.47 0.912 29 248 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1 0.657 – 1.53 0.992 24 258 exclusion phecode
750.14 Congenital anomalies of esophagus Congenital Anomalies 0.972 0.698 – 1.35 0.864 39 269 exclusion phecode
750.15 Congenital anomalies of stomach Congenital Anomalies 0.86 0.438 – 1.69 0.662 11 122 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.19 1.01 – 1.4 0.0414 176 1251 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.25 1.02 – 1.54 0.0304 110 720 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.13 0.849 – 1.5 0.406 69 509 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.05 0.955 – 1.16 0.311 518 4659 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.05 0.886 – 1.25 0.561 161 1548 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.22 0.995 – 1.51 0.0558 116 1100 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.792 0.559 – 1.12 0.188 38 353 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.02 0.902 – 1.14 0.791 332 3026 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 1.06 0.92 – 1.23 0.409 227 2060 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.957 0.748 – 1.22 0.724 74 675 exclusion phecode
751.3 Obstructive genitourinary defect Congenital Anomalies 1.3 0.98 – 1.73 0.0685 62 532 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.09 0.944 – 1.26 0.242 227 2647 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.16 0.988 – 1.36 0.0712 177 2072 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.953 0.694 – 1.31 0.769 42 500 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.914 0.686 – 1.22 0.541 58 599 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.06 0.781 – 1.44 0.699 52 476 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.89 0.507 – 1.56 0.685 14 150 exclusion phecode
753.2 Congenital anomalies of posterior segment of eye Congenital Anomalies 0.746 0.418 – 1.33 0.319 14 144 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.14 0.993 – 1.31 0.0632 247 2582 exclusion phecode
754.1 Lumbosacral spondylolysis, congenital Congenital Anomalies 0.908 0.591 – 1.4 0.66 27 305 exclusion phecode
754.2 Spondylolisthesis, congenital Congenital Anomalies 1.1 0.901 – 1.35 0.34 109 1222 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.05 0.892 – 1.23 0.573 175 1999 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.966 0.763 – 1.22 0.772 78 912 exclusion phecode
755.4
Congenital anomalies of upper limb, including
Congenital anomalies of upper limb, including shoulder girdle
 Congenital Anomalies 1.21 0.749 – 1.96 0.437 18 180 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.05 0.831 – 1.33 0.678 84 961 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.01 0.747 – 1.37 0.947 50 565 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.04 0.93 – 1.17 0.472 354 3352 exclusion phecode
756.1 Congenital anomalies of abdominal wall; diaphram Congenital Anomalies 0.516 0.302 – 0.881 0.0152 21 172 exclusion phecode
756.2
Pectus and other congenital anomalies of
Pectus and other congenital anomalies of ribs/sternum
 Congenital Anomalies 1.18 0.848 – 1.63 0.331 49 237 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.988 0.763 – 1.28 0.924 62 840 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.06 0.923 – 1.22 0.401 229 2290 exclusion phecode
757 Congenital anomalies of the integument Congenital Anomalies 0.806 0.649 – 1 0.0518 103 926 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.08 0.814 – 1.44 0.583 58 491 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.09 0.775 – 1.52 0.634 38 363 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.913 0.773 – 1.08 0.288 160 1493 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.718 0.418 – 1.23 0.229 14 188 exclusion phecode
760 Back pain Symptoms 1.09 1.05 – 1.14 5.13e-05 3440 7569 exclusion phecode
761 Cervicalgia Symptoms 1.06 1.01 – 1.13 0.0324 1576 9228 exclusion phecode
763
Thoracic or lumbosacral neuritis or
Thoracic or lumbosacral neuritis or radiculitis, unspecified
 Symptoms 1.06 0.976 – 1.16 0.16 662 7263 exclusion phecode
764 Sciatica Symptoms 1.1 1 – 1.2 0.0391 611 7266 exclusion phecode
765 Cervical radiculitis Symptoms 1.08 0.971 – 1.21 0.152 371 3862 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.09 1.01 – 1.16 0.0194 1017 8661 exclusion phecode
767 Cervicocranial/Cervicobrachial syndrome Symptoms 1.19 0.783 – 1.8 0.419 28 264 exclusion phecode
769 Nonallopathic lesions NEC Symptoms 1.03 0.903 – 1.18 0.657 292 2634 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.06 0.994 – 1.13 0.0776 1254 8242 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.11 1.03 – 1.19 0.00342 1015 8355 exclusion phecode
771.1 Swelling of limb Symptoms 1.13 1.05 – 1.21 0.000569 1061 8316 exclusion phecode
771.2 Cramp of limb Symptoms 1.1 0.96 – 1.27 0.166 233 2375 exclusion phecode
772 Symptoms of the muscles Symptoms 0.986 0.896 – 1.09 0.774 507 4726 exclusion phecode
772.1 Muscular wasting and disuse atrophy Symptoms 1.06 0.876 – 1.29 0.532 123 1091 exclusion phecode
772.2 Spasm of muscle Symptoms 0.976 0.889 – 1.07 0.61 542 5508 exclusion phecode
772.3 Muscle weakness Symptoms 1.06 0.977 – 1.16 0.152 640 6137 exclusion phecode
772.4 Rhabdomyolysis Symptoms 1.36 0.937 – 1.96 0.107 38 338 exclusion phecode
772.6 Facial weakness Symptoms 0.988 0.794 – 1.23 0.915 96 1027 exclusion phecode
780 Hypothermia/Chills Symptoms 1.19 0.962 – 1.46 0.11 104 987 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.972 0.888 – 1.06 0.543 574 5709 exclusion phecode
781.1 Loss of height Symptoms 1.16 0.804 – 1.68 0.424 35 214 exclusion phecode
781.2 Abnormal posture Symptoms 0.859 0.481 – 1.54 0.609 14 123 exclusion phecode
782.3 Edema Symptoms 1.23 1.15 – 1.32 8.75e-09 976 8470 exclusion phecode
782.6 Pallor and flushing Symptoms 0.886 0.77 – 1.02 0.0894 245 2410 exclusion phecode
783 Fever of unknown origin Symptoms 1.15 1.08 – 1.22 7.78e-06 1350 9562 exclusion phecode
783.1 Postprocedural fever Symptoms 1.05 0.794 – 1.4 0.718 58 642 exclusion phecode
785 Abdominal pain Symptoms 1.07 1.03 – 1.12 0.000744 3950 7061 exclusion phecode
788 Syncope and collapse Symptoms 1.06 0.99 – 1.15 0.0923 887 8223 exclusion phecode
789 Nausea and vomiting Symptoms 1.11 1.06 – 1.16 1.63e-05 2685 8302 exclusion phecode
789.1 Persistent vomiting Symptoms 1.31 1.13 – 1.52 0.000462 203 1910 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.09 0.992 – 1.21 0.0735 499 4987 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.08 0.785 – 1.5 0.621 42 564 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.12 1.05 – 1.18 0.000288 1441 9098 exclusion phecode
790.8 Elevated C-reactive protein (CRP) Symptoms 0.994 0.739 – 1.34 0.967 46 771 exclusion phecode
790.9 Abnormal arterial blood gases Symptoms 1.24 0.848 – 1.83 0.263 27 339 exclusion phecode
791 Gangrene Symptoms 1.27 0.999 – 1.62 0.0509 77 589 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Genitourinary 1.01 0.938 – 1.09 0.738 885 4183 exclusion phecode
792.1
Papanicolaou smear of cervix or vagina with
Papanicolaou smear of cervix or vagina with atypical squamous cells
 Genitourinary 1.04 0.927 – 1.16 0.511 370 2793 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.99 0.797 – 1.23 0.929 96 1118 exclusion phecode
795
Other and nonspecific abnormal cytological
Other and nonspecific abnormal cytological, histological and immunological findings
 Symptoms 1.04 0.957 – 1.14 0.325 639 5303 exclusion phecode
795.8 Abnormal tumor markers Symptoms 0.911 0.804 – 1.03 0.143 295 2567 exclusion phecode
795.81 Elevated carcinoembryonic antigen [CEA] Symptoms 1.01 0.53 – 1.91 0.982 11 129 exclusion phecode
795.82 Elevated cancer antigen 125 [CA 125] Symptoms 1.02 0.765 – 1.35 0.906 59 490 exclusion phecode
796 Elevated prostate specific antigen [PSA] Genitourinary 0.798 0.698 – 0.912 0.000946 314 1514 exclusion phecode
797 Shock Symptoms 1.25 1.03 – 1.53 0.0276 129 1151 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.19 0.868 – 1.64 0.275 54 436 exclusion phecode
798 Malaise and fatigue Symptoms 1.08 1.03 – 1.13 0.00131 2655 8349 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1.07 0.962 – 1.2 0.207 383 4177 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.12 1.02 – 1.23 0.0125 595 5364 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.18 0.978 – 1.41 0.0843 151 1086 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.15 0.98 – 1.35 0.0878 192 1460 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.22 1.05 – 1.4 0.00804 221 2131 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.938 0.758 – 1.16 0.553 105 871 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.05 0.954 – 1.15 0.337 536 5414 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.09 0.951 – 1.25 0.22 249 2719 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.08 0.889 – 1.32 0.429 123 885 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.984 0.901 – 1.07 0.714 608 4860 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1.13 0.961 – 1.33 0.137 177 1770 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.981 0.873 – 1.1 0.739 360 2789 exclusion phecode
803.21 Colles' fracture Injuries & Poisonings 0.973 0.776 – 1.22 0.812 93 688 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.9 0.767 – 1.06 0.196 176 1228 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.991 0.898 – 1.09 0.854 491 3985 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.09 0.971 – 1.23 0.141 347 2856 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.04 0.887 – 1.23 0.609 177 1371 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.03 0.953 – 1.11 0.485 829 6736 exclusion phecode
816 Cerebral laceration and contusion Injuries & Poisonings 1.59 0.892 – 2.84 0.116 16 101 exclusion phecode
817 Concussion Injuries & Poisonings 1.06 0.929 – 1.22 0.374 258 2679 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.12 0.887 – 1.41 0.339 85 688 exclusion phecode
818.1 Subdural hemorrhage (injury) Injuries & Poisonings 1.23 0.766 – 1.96 0.395 24 189 exclusion phecode
818.2 Subarachnoid hemorrhage (injury) Injuries & Poisonings 0.973 0.595 – 1.59 0.914 24 203 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.04 0.956 – 1.14 0.341 607 5516 exclusion phecode
830 Dislocation Injuries & Poisonings 0.911 0.847 – 0.981 0.0133 868 8371 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.899 0.813 – 0.993 0.0357 465 5322 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.936 0.738 – 1.19 0.586 80 1028 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.942 0.893 – 0.994 0.0287 1782 9030 exclusion phecode
840.1 Muscle/tendon sprain Injuries & Poisonings 1.01 0.794 – 1.27 0.959 82 1115 exclusion phecode
840.2 Rotator cuff (capsule) sprain Injuries & Poisonings 0.94 0.82 – 1.08 0.382 253 3256 exclusion phecode
840.3 Joint/ligament sprain Injuries & Poisonings 0.899 0.83 – 0.974 0.00906 746 6296 exclusion phecode
841 Sprains and strains of back and neck Injuries & Poisonings 0.958 0.851 – 1.08 0.476 339 3848 exclusion phecode
842 Other sprains and strains Injuries & Poisonings 1.02 0.911 – 1.15 0.691 334 3490 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.1 0.999 – 1.22 0.0533 461 4470 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.22 1.13 – 1.33 1.64e-06 669 5863 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.41 1.14 – 1.73 0.00126 107 959 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.22 1.09 – 1.35 0.000289 412 4147 exclusion phecode
855
Complication of nervous system device, implant
Complication of nervous system device, implant, and graft
 Injuries & Poisonings 1.11 0.824 – 1.48 0.503 54 619 exclusion phecode
856
Vascular complications of surgery and medical
Vascular complications of surgery and medical procedures
 Injuries & Poisonings 1.17 0.885 – 1.55 0.269 59 578 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.12 0.98 – 1.28 0.0969 269 3092 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.12 1.02 – 1.23 0.0193 517 5130 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.2 1.1 – 1.32 7.82e-05 567 4779 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.33 0.933 – 1.89 0.115 40 366 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.05 0.983 – 1.13 0.14 997 8403 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.29 0.969 – 1.73 0.0806 55 444 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 0.795 0.57 – 1.11 0.176 41 324 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.984 0.881 – 1.1 0.773 392 3010 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.03 0.781 – 1.35 0.853 60 476 exclusion phecode
870.5 Open wound of lip and mouth Injuries & Poisonings 1.15 0.914 – 1.45 0.231 93 604 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.871 0.671 – 1.13 0.299 64 395 exclusion phecode
870.8 Open wound of genital organs Injuries & Poisonings 1 0.704 – 1.43 0.983 38 391 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.09 1.01 – 1.17 0.0338 808 7420 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.05 0.869 – 1.26 0.638 128 1282 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.969 0.843 – 1.11 0.658 233 2284 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.53 1.22 – 1.93 0.000305 85 951 exclusion phecode
871.4 Open wound of toe(s) Injuries & Poisonings 1.27 0.93 – 1.75 0.131 44 583 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.31 1.07 – 1.6 0.00764 109 1075 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.61 1.13 – 2.28 0.00862 34 304 exclusion phecode
875 Non-healing surgical wound Injuries & Poisonings 1.06 0.878 – 1.29 0.536 127 1275 exclusion phecode
876
Posttraumatic wound infection not elsewhere
Posttraumatic wound infection not elsewhere classified
 Injuries & Poisonings 1.09 0.915 – 1.29 0.345 148 1736 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.1 0.959 – 1.27 0.173 237 2291 exclusion phecode
910 Superficial injury, infected Injuries & Poisonings 0.859 0.548 – 1.35 0.508 22 268 exclusion phecode
911 Blister Injuries & Poisonings 1.04 0.771 – 1.41 0.792 50 571 exclusion phecode
912 Insect bite Injuries & Poisonings 0.986 0.804 – 1.21 0.894 112 1187 exclusion phecode
913 Toxic effect of venom Injuries & Poisonings 0.785 0.631 – 0.977 0.0304 85 744 exclusion phecode
916 Contusion Injuries & Poisonings 1.07 1 – 1.15 0.0443 987 8993 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 1.02 0.874 – 1.2 0.762 184 2047 exclusion phecode
931
Contact dermatitis and other eczema due to
Contact dermatitis and other eczema due to plants [except food]
 Dermatologic 0.922 0.768 – 1.11 0.385 149 1629 exclusion phecode
938 Dermatitis due to solar radiation Dermatologic 0.897 0.842 – 0.956 0.000829 1328 6321 exclusion phecode
938.1 Acute dermatitis due to solar radiation Dermatologic 0.892 0.658 – 1.21 0.459 48 508 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Dermatologic 0.891 0.835 – 0.951 0.00054 1269 6176 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.997 0.939 – 1.06 0.917 1492 7699 exclusion phecode
939.1 Contact and allergic dermatitis of eyelid Dermatologic 1.25 0.804 – 1.95 0.319 28 224 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.91 0.637 – 1.3 0.606 37 380 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.28 0.987 – 1.67 0.063 76 617 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.939 0.775 – 1.14 0.519 125 1147 exclusion phecode
947 Urticaria Dermatologic 1.01 0.889 – 1.15 0.884 287 2944 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.05 0.996 – 1.12 0.0696 1617 7675 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.11 0.906 – 1.36 0.314 107 1049 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.683 0.472 – 0.989 0.0433 34 324 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.05 0.933 – 1.19 0.398 305 2721 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 0.923 0.645 – 1.32 0.661 38 329 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.17 0.8 – 1.7 0.422 34 249 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.21 1.1 – 1.33 5.8e-05 552 5167 exclusion phecode
960.1
Adverse effects of antibacterials (not
Adverse effects of antibacterials (not penicillins)
 Injuries & Poisonings 1.15 0.905 – 1.45 0.258 88 767 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.22 1.09 – 1.38 0.000813 342 3712 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.32 1.09 – 1.59 0.00431 138 1185 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.24 1.08 – 1.44 0.0032 233 2385 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.21 1.03 – 1.43 0.0225 172 1659 exclusion phecode
962.1
Adrenal cortical steroids causing adverse
Adrenal cortical steroids causing adverse effects in therapeutic use
 Injuries & Poisonings 1.22 0.965 – 1.54 0.0968 84 794 exclusion phecode
962.2
Insulins and antidiabetic agents causing
Insulins and antidiabetic agents causing adverse effects in therapeutic use
 Injuries & Poisonings 2.11 1.07 – 4.18 0.0315 11 118 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.15 0.93 – 1.43 0.192 99 974 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.15 1.06 – 1.25 0.00138 662 5444 exclusion phecode
963.1
Antineoplastic and immunosuppressive drugs
Antineoplastic and immunosuppressive drugs causing adverse effects
 Injuries & Poisonings 1.16 1.06 – 1.26 0.00114 644 5337 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.14 0.938 – 1.38 0.189 129 1472 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.13 0.925 – 1.38 0.233 120 1391 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.11 0.955 – 1.3 0.17 199 2115 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.35 1.19 – 1.52 2.69e-06 303 3397 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.975 0.65 – 1.46 0.903 27 247 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.15 0.751 – 1.77 0.514 28 229 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.05 0.925 – 1.19 0.447 305 2905 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.38 1.08 – 1.78 0.0113 74 697 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.65 0.97 – 2.8 0.0644 18 124 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.55 1.14 – 2.1 0.00529 51 576 exclusion phecode
972.1
Cardiac rhythm regulators causing adverse
Cardiac rhythm regulators causing adverse effects in therapeutic use
 Injuries & Poisonings 1.4 0.851 – 2.31 0.185 13 157 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.91 1.12 – 3.24 0.0171 16 198 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.72 1.07 – 2.78 0.0257 21 234 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.851 0.488 – 1.49 0.57 14 199 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.728 0.41 – 1.29 0.277 15 160 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.14 1.02 – 1.28 0.0188 383 3849 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.15 1.07 – 1.25 0.000313 797 7171 exclusion phecode
980
Encounter for long-term (current) use of
Encounter for long-term (current) use of antibiotics
 Infectious Diseases 1.01 0.891 – 1.15 0.872 288 2809 exclusion phecode
985 Toxic effect of other metals Injuries & Poisonings 1.66 0.864 – 3.19 0.128 17 92 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.16 0.822 – 1.64 0.4 34 302 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.13 1.05 – 1.21 0.00116 954 6503 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.28 1.15 – 1.41 2.92e-06 461 4485 exclusion phecode
994.1 Systemic inflammatory response syndrome (SIRS) Injuries & Poisonings 1.24 0.958 – 1.61 0.102 74 650 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.25 1.13 – 1.39 3.08e-05 429 4266 exclusion phecode
994.21 Septic shock Injuries & Poisonings 1.3 1.08 – 1.57 0.00619 138 1270 exclusion phecode
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