Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores C-reactive protein UK Biobank (UKB) PheWAS analysis

C-reactive protein — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID exprsweb-c-reactive-protein-prot-a-670-lassosum-ukb-20211120Legacy LASSOSUMlassosumLarge GWAS

Evaluation cohort: UK Biobank (UKB).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: normal-range subset (0.01-0.3 mg/dl).

For this ExPRS, the exclusion sensitivity scan keeps only the study's normal-range subset for C-reactive protein (0.01-0.3 mg/dl) before rerunning the PheWAS. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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Signal overview

The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.

118 rows visible 16 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 0.986 0.964 – 1.01 0.194 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 0.991 0.952 – 1.03 0.639 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.06 0.98 – 1.15 0.142 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 0.931 0.869 – 0.998 0.0443 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 0.799 0.61 – 1.05 0.102 55 550 all phecode
010 Tuberculosis Infectious Diseases 0.96 0.82 – 1.12 0.612 166 1659 all phecode
038 Septicemia Infectious Diseases 1.03 0.999 – 1.07 0.0541 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.07 0.997 – 1.15 0.06 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 0.977 0.891 – 1.07 0.62 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 0.993 0.975 – 1.01 0.482 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 1 0.967 – 1.04 0.862 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 0.99 0.941 – 1.04 0.704 1641 16433 all phecode
041.4 E. coli Infectious Diseases 0.978 0.94 – 1.02 0.27 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 0.94 0.85 – 1.04 0.228 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.865 0.708 – 1.06 0.153 95 949 all phecode
054 Herpes simplex Infectious Diseases 1.02 0.886 – 1.17 0.821 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 1.01 0.931 – 1.1 0.764 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 1 0.781 – 1.28 1 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 0.984 0.823 – 1.18 0.858 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 0.942 0.83 – 1.07 0.352 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.01 0.89 – 1.14 0.905 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.02 0.921 – 1.12 0.734 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.05 0.889 – 1.25 0.546 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.06 0.873 – 1.28 0.577 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 0.977 0.916 – 1.04 0.468 1004 10036 all phecode
079 Viral infection Infectious Diseases 0.974 0.937 – 1.01 0.188 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 0.879 0.685 – 1.13 0.313 64 640 all phecode
080 Postoperative infection Infectious Diseases 0.986 0.956 – 1.02 0.369 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.01 0.973 – 1.06 0.494 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.17 0.919 – 1.48 0.206 71 709 all phecode
1000 Burns Injuries & Poisonings 0.962 0.883 – 1.05 0.37 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 0.999 0.94 – 1.06 0.966 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 0.988 0.961 – 1.02 0.408 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.06 0.934 – 1.19 0.387 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 1.03 0.973 – 1.08 0.332 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 1.05 0.919 – 1.19 0.499 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 0.936 0.822 – 1.07 0.319 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1 0.94 – 1.07 0.929 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 0.985 0.964 – 1.01 0.194 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 1 0.977 – 1.03 0.797 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.02 0.998 – 1.04 0.0815 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 0.999 0.82 – 1.22 0.996 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.01 0.901 – 1.13 0.849 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.911 0.721 – 1.15 0.438 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 0.978 0.947 – 1.01 0.161 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 0.998 0.982 – 1.01 0.802 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.03 0.911 – 1.17 0.631 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 1.05 0.925 – 1.19 0.461 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.06 0.837 – 1.35 0.608 74 756 all phecode
110.12 Althete's foot Infectious Diseases 1.04 0.877 – 1.23 0.654 141 1410 all phecode
112 Candidiasis Infectious Diseases 0.984 0.941 – 1.03 0.479 2126 21275 all phecode
117 Mycoses Infectious Diseases 0.957 0.844 – 1.09 0.493 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 0.931 0.795 – 1.09 0.372 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 1.13 0.901 – 1.42 0.289 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 1.02 0.798 – 1.3 0.888 69 689 all phecode
134 Helminthiases Infectious Diseases 1.04 0.863 – 1.25 0.693 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 0.962 0.788 – 1.17 0.703 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.965 0.837 – 1.11 0.622 205 2050 all phecode
145 Cancer of mouth Neoplasms 1.05 0.964 – 1.14 0.279 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 1.12 0.994 – 1.26 0.0629 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 0.992 0.811 – 1.21 0.937 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.17 0.874 – 1.58 0.285 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.02 0.944 – 1.11 0.573 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 1.04 0.915 – 1.19 0.54 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 0.971 0.857 – 1.1 0.64 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.827 0.636 – 1.08 0.157 57 570 all phecode
150 Cancer of esophagus Neoplasms 1.01 0.941 – 1.09 0.705 762 7630 all phecode
151 Cancer of stomach Neoplasms 1.04 0.95 – 1.13 0.424 569 5696 all phecode
153 Colorectal cancer Neoplasms 0.97 0.941 – 1 0.0473 4580 45799 all phecode
153.2 Colon cancer Neoplasms 0.968 0.933 – 1 0.0867 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.99 0.947 – 1.03 0.646 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.997 0.9 – 1.11 0.961 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.99 0.84 – 1.17 0.905 158 1580 all phecode
157 Pancreatic cancer Neoplasms 0.98 0.905 – 1.06 0.612 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.05 0.982 – 1.11 0.159 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.976 0.95 – 1 0.0863 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.03 0.886 – 1.2 0.701 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.17 1.01 – 1.36 0.0318 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.993 0.856 – 1.15 0.925 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 1.19 0.922 – 1.54 0.18 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 1.01 0.973 – 1.05 0.548 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.02 0.976 – 1.07 0.376 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.984 0.893 – 1.08 0.749 437 4364 all phecode
170.1 Bone cancer Neoplasms 0.949 0.797 – 1.13 0.554 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 0.991 0.888 – 1.11 0.879 331 3303 all phecode
172 Skin cancer Neoplasms 0.99 0.972 – 1.01 0.26 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.01 0.975 – 1.06 0.468 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 1.02 0.977 – 1.06 0.425 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.988 0.969 – 1.01 0.236 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.05 0.971 – 1.14 0.214 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.889 0.767 – 1.03 0.119 181 1818 all phecode
174 Breast cancer Neoplasms 1 0.983 – 1.02 0.88 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 1 0.986 – 1.02 0.674 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1 0.986 – 1.02 0.637 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.927 0.766 – 1.12 0.432 115 1148 all phecode
175 Acquired absence of breast Neoplasms 1 0.961 – 1.05 0.901 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 1.01 0.97 – 1.06 0.546 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 0.96 0.851 – 1.08 0.508 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.03 0.981 – 1.07 0.269 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 0.981 0.926 – 1.04 0.506 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 1.01 0.953 – 1.06 0.794 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.989 0.926 – 1.06 0.744 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.979 0.916 – 1.05 0.54 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.07 0.949 – 1.21 0.271 305 3049 all phecode
185 Cancer of prostate Neoplasms 1.03 0.999 – 1.05 0.0628 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 0.922 0.838 – 1.01 0.0949 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.864 0.67 – 1.11 0.258 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.976 0.866 – 1.1 0.693 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1 0.828 – 1.21 0.995 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.02 0.986 – 1.05 0.273 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1 0.941 – 1.07 0.935 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.998 0.936 – 1.06 0.949 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.939 0.733 – 1.2 0.62 66 660 all phecode
189.2 Cancer of bladder Neoplasms 1.01 0.97 – 1.06 0.587 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.01 0.964 – 1.05 0.719 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.997 0.843 – 1.18 0.968 144 1439 all phecode
190 Cancer of eye Neoplasms 0.882 0.755 – 1.03 0.113 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1 0.926 – 1.08 0.962 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1.02 0.932 – 1.11 0.709 566 5650 all phecode
191.11 Cancer of brain Neoplasms 1.02 0.932 – 1.12 0.679 525 5240 all phecode
193 Thyroid cancer Neoplasms 1.06 0.951 – 1.19 0.286 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 0.978 0.801 – 1.19 0.824 95 949 all phecode
195 Cancer, suspected or other Neoplasms 1.01 0.99 – 1.02 0.44 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.01 0.992 – 1.02 0.346 16267 159497 all phecode
197 Chemotherapy Neoplasms 1 0.988 – 1.02 0.734 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 0.999 0.978 – 1.02 0.911 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.999 0.971 – 1.03 0.955 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.04 0.993 – 1.08 0.0965 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.06 1 – 1.11 0.0406 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 0.995 0.956 – 1.03 0.786 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.986 0.919 – 1.06 0.691 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 0.986 0.943 – 1.03 0.528 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.887 0.763 – 1.03 0.123 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.01 0.961 – 1.07 0.61 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 1.18 0.956 – 1.46 0.122 95 950 all phecode
200 Myeloproliferative disease Neoplasms 1.08 1.01 – 1.15 0.0233 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 1.11 1 – 1.24 0.0487 387 3867 all phecode
201 Hodgkin's disease Neoplasms 0.883 0.781 – 0.998 0.046 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.02 0.98 – 1.07 0.297 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.01 0.964 – 1.06 0.63 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 1.14 1.02 – 1.27 0.0196 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 0.98 0.901 – 1.07 0.645 581 5824 all phecode
204 Leukemia Neoplasms 1.02 0.966 – 1.07 0.531 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 1.05 0.967 – 1.15 0.236 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.864 0.662 – 1.13 0.281 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.07 0.973 – 1.17 0.17 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 1.01 0.917 – 1.11 0.863 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.949 0.849 – 1.06 0.358 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.23 1.04 – 1.46 0.0178 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 1.03 0.945 – 1.13 0.488 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 0.99 0.976 – 1 0.185 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.992 0.929 – 1.06 0.822 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.999 0.971 – 1.03 0.945 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.982 0.879 – 1.1 0.74 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.02 0.914 – 1.15 0.688 318 3187 all phecode
214 Lipoma Neoplasms 0.992 0.966 – 1.02 0.546 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.993 0.963 – 1.02 0.633 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.02 0.959 – 1.08 0.532 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 1.02 0.994 – 1.04 0.134 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.969 0.893 – 1.05 0.444 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 0.966 0.888 – 1.05 0.415 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 0.981 0.962 – 1 0.073 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 0.983 0.964 – 1 0.106 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.979 0.877 – 1.09 0.705 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 0.991 0.939 – 1.05 0.732 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.09 0.945 – 1.25 0.242 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.885 0.752 – 1.04 0.138 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1 0.86 – 1.17 0.988 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 1.04 0.87 – 1.24 0.675 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.961 0.756 – 1.22 0.747 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.02 0.949 – 1.1 0.582 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.02 0.946 – 1.1 0.627 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.01 0.77 – 1.33 0.933 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.11 0.981 – 1.27 0.0946 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.02 0.953 – 1.1 0.539 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.17 1 – 1.37 0.0477 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.999 0.898 – 1.11 0.982 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.948 0.844 – 1.07 0.372 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.01 0.962 – 1.07 0.636 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.01 0.973 – 1.06 0.511 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.921 0.847 – 1 0.0569 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.991 0.93 – 1.05 0.77 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.955 0.869 – 1.05 0.342 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.01 0.927 – 1.09 0.886 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1 0.954 – 1.05 0.971 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 0.975 0.886 – 1.07 0.608 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.4 1.11 – 1.75 0.00414 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.06 0.88 – 1.27 0.559 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 1 0.987 – 1.02 0.64 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.02 0.955 – 1.08 0.601 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.911 0.746 – 1.11 0.361 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1 0.986 – 1.02 0.677 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 1 0.888 – 1.13 0.981 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.07 0.935 – 1.23 0.311 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.1 0.958 – 1.27 0.171 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.08 0.972 – 1.2 0.152 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.01 0.991 – 1.02 0.471 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.02 0.983 – 1.06 0.264 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.995 0.872 – 1.14 0.946 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.791 0.625 – 1 0.051 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.976 0.887 – 1.07 0.609 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.01 0.854 – 1.19 0.924 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1 0.989 – 1.02 0.61 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.01 0.825 – 1.23 0.947 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.969 0.836 – 1.12 0.673 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.01 0.948 – 1.08 0.715 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.03 0.94 – 1.13 0.515 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.04 0.959 – 1.12 0.36 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.984 0.87 – 1.11 0.803 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.08 0.971 – 1.19 0.163 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.04 0.87 – 1.25 0.662 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.06 0.951 – 1.19 0.283 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.992 0.937 – 1.05 0.789 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.02 0.955 – 1.09 0.537 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.08 1 – 1.16 0.0407 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.09 1.01 – 1.17 0.0317 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.11 0.931 – 1.32 0.245 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.955 0.883 – 1.03 0.257 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.974 0.839 – 1.13 0.731 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.923 0.754 – 1.13 0.435 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.974 0.859 – 1.11 0.688 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.82 0.663 – 1.01 0.0656 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.902 0.767 – 1.06 0.212 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.993 0.917 – 1.08 0.872 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.07 0.922 – 1.25 0.366 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.06 0.876 – 1.29 0.529 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.08 0.856 – 1.36 0.518 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.941 0.847 – 1.05 0.259 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.941 0.846 – 1.05 0.256 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.04 0.913 – 1.19 0.542 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.978 0.849 – 1.13 0.753 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 0.888 0.758 – 1.04 0.14 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.896 0.762 – 1.05 0.183 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.954 0.779 – 1.17 0.647 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 0.998 0.843 – 1.18 0.979 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.945 0.816 – 1.09 0.449 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 0.882 0.666 – 1.17 0.382 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 1 0.931 – 1.07 0.992 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 1 0.946 – 1.06 0.909 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.981 0.91 – 1.06 0.607 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.03 0.936 – 1.13 0.535 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.04 0.831 – 1.29 0.756 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.978 0.86 – 1.11 0.73 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 0.996 0.892 – 1.11 0.947 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.96 0.857 – 1.08 0.483 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.947 0.836 – 1.07 0.392 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 0.948 0.82 – 1.1 0.472 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 0.963 0.795 – 1.17 0.702 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.01 0.789 – 1.28 0.961 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.05 0.893 – 1.24 0.555 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.07 0.903 – 1.28 0.423 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.95 0.939 – 0.961 8.75e-19 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.95 0.939 – 0.961 7.86e-19 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.948 0.937 – 0.959 6.03e-19 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.989 0.747 – 1.31 0.939 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.914 0.781 – 1.07 0.26 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.969 0.843 – 1.11 0.653 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.991 0.958 – 1.03 0.613 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 0.998 0.962 – 1.03 0.898 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.861 0.717 – 1.03 0.107 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.941 0.866 – 1.02 0.152 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.936 0.858 – 1.02 0.139 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.02 0.978 – 1.07 0.322 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 1.02 0.94 – 1.1 0.659 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 0.953 0.858 – 1.06 0.375 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.05 0.989 – 1.11 0.109 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.03 0.882 – 1.21 0.696 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 0.963 0.94 – 0.986 0.00198 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 0.952 0.922 – 0.983 0.00265 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.935 0.82 – 1.07 0.311 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 0.966 0.921 – 1.01 0.162 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 0.91 0.853 – 0.971 0.00453 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 0.954 0.903 – 1.01 0.0915 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.958 0.902 – 1.02 0.164 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 0.958 0.899 – 1.02 0.184 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 0.99 0.819 – 1.2 0.916 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 0.966 0.93 – 1 0.0824 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 0.926 0.842 – 1.02 0.111 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 1.03 0.86 – 1.22 0.773 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 0.993 0.927 – 1.06 0.836 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.06 0.948 – 1.18 0.321 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.01 0.885 – 1.16 0.848 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.994 0.75 – 1.32 0.964 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.01 0.995 – 1.04 0.145 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 1.02 0.996 – 1.04 0.128 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 1 0.812 – 1.23 0.99 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.993 0.77 – 1.28 0.955 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.08 0.946 – 1.23 0.256 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1.09 0.943 – 1.26 0.245 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.04 0.87 – 1.24 0.687 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.01 0.883 – 1.15 0.899 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 0.991 0.968 – 1.02 0.476 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.994 0.97 – 1.02 0.601 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.922 0.837 – 1.01 0.0973 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 1.04 0.982 – 1.11 0.167 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 1.05 0.985 – 1.12 0.132 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 1.07 0.99 – 1.15 0.092 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.994 0.854 – 1.16 0.938 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 1.01 0.868 – 1.18 0.871 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 0.922 0.707 – 1.2 0.55 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.14 0.963 – 1.35 0.13 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.27 0.963 – 1.68 0.0899 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.06 0.849 – 1.33 0.591 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.23 1.03 – 1.46 0.0228 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.42 1.15 – 1.76 0.00105 103 1059 all phecode
284 Aplastic anemia Hematopoietic 0.929 0.842 – 1.02 0.139 435 4357 all phecode
285 Other anemias Hematopoietic 0.994 0.976 – 1.01 0.53 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.01 0.889 – 1.14 0.902 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 0.921 0.851 – 0.996 0.0388 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.945 0.854 – 1.05 0.276 414 4147 all phecode
286 Coagulation defects Hematopoietic 1.03 0.958 – 1.1 0.472 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 0.993 0.903 – 1.09 0.881 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 0.951 0.774 – 1.17 0.631 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.03 0.919 – 1.16 0.578 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 0.814 0.629 – 1.05 0.119 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.06 0.851 – 1.33 0.585 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.09 0.976 – 1.21 0.13 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.98 0.932 – 1.03 0.433 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.08 0.901 – 1.28 0.42 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 0.973 0.734 – 1.29 0.848 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 0.975 0.926 – 1.03 0.341 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.05 0.948 – 1.16 0.359 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.876 0.695 – 1.11 0.266 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 0.992 0.959 – 1.03 0.631 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 0.997 0.961 – 1.03 0.891 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 0.997 0.961 – 1.03 0.884 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 0.866 0.682 – 1.1 0.24 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.961 0.897 – 1.03 0.257 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.935 0.831 – 1.05 0.27 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 1.02 0.976 – 1.06 0.447 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 1.11 1.01 – 1.21 0.0307 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.04 0.926 – 1.18 0.479 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 0.969 0.786 – 1.19 0.766 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.821 0.784 – 0.86 6.26e-17 1929 19281 all phecode
290.1 Dementias Mental Disorders 0.727 0.683 – 0.775 1.07e-22 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 0.683 0.62 – 0.753 2.09e-14 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 0.705 0.61 – 0.815 2.18e-06 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.909 0.84 – 0.984 0.0187 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.939 0.749 – 1.18 0.585 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.978 0.911 – 1.05 0.538 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.03 0.862 – 1.23 0.748 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.967 0.859 – 1.09 0.584 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 0.98 0.889 – 1.08 0.689 436 4376 all phecode
292 Neurological disorders Mental Disorders 0.926 0.899 – 0.954 5.47e-07 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.939 0.891 – 0.99 0.0198 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.936 0.808 – 1.09 0.383 190 1907 all phecode
292.3 Memory loss Mental Disorders 0.892 0.826 – 0.963 0.00342 696 6978 all phecode
292.4 Altered mental status Mental Disorders 0.952 0.911 – 0.995 0.0297 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 0.84 0.75 – 0.942 0.00275 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 1.03 0.98 – 1.07 0.282 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1 0.935 – 1.07 0.975 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.991 0.923 – 1.06 0.804 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 0.98 0.899 – 1.07 0.645 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 1.01 0.861 – 1.17 0.946 178 1780 all phecode
295.3 Psychosis Mental Disorders 0.956 0.82 – 1.11 0.561 169 1710 all phecode
296 Mood disorders Mental Disorders 1 0.985 – 1.02 0.741 12372 123822 all phecode
296.1 Bipolar Mental Disorders 0.983 0.923 – 1.05 0.594 1059 10599 all phecode
296.2 Depression Mental Disorders 1 0.981 – 1.02 0.997 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 1 0.899 – 1.12 0.935 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.06 0.941 – 1.19 0.356 311 3070 all phecode
300 Anxiety disorders Mental Disorders 1.01 0.982 – 1.03 0.619 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 1 0.978 – 1.03 0.775 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1.06 0.893 – 1.26 0.507 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.98 0.908 – 1.06 0.595 707 7065 all phecode
300.13 Phobia Mental Disorders 0.957 0.875 – 1.05 0.332 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.05 0.875 – 1.25 0.627 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 1.1 0.827 – 1.46 0.512 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 1.02 0.85 – 1.23 0.81 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.13 0.923 – 1.38 0.24 113 1129 all phecode
301 Personality disorders Mental Disorders 0.949 0.847 – 1.06 0.362 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.964 0.798 – 1.16 0.7 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 1.04 0.921 – 1.18 0.508 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.04 0.947 – 1.15 0.401 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 1.07 0.958 – 1.2 0.223 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 0.97 0.808 – 1.16 0.739 123 1229 all phecode
304 Adjustment reaction Mental Disorders 0.975 0.864 – 1.1 0.683 293 2936 all phecode
305.2 Eating disorder Mental Disorders 0.917 0.738 – 1.14 0.435 90 900 all phecode
306 Other mental disorder Mental Disorders 0.996 0.983 – 1.01 0.484 28056 230087 all phecode
306.9 Tension headache Mental Disorders 0.923 0.823 – 1.03 0.168 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 0.992 0.785 – 1.26 0.949 76 770 all phecode
313.3 Autism Mental Disorders 1.01 0.762 – 1.34 0.945 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 0.937 0.839 – 1.05 0.244 351 3517 all phecode
315.1 Learning disorder Mental Disorders 1.1 0.935 – 1.29 0.252 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 0.857 0.688 – 1.07 0.17 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 1.02 0.988 – 1.05 0.248 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.05 0.805 – 1.38 0.699 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 1.01 0.992 – 1.03 0.267 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 1.01 0.986 – 1.03 0.493 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.07 0.993 – 1.14 0.0753 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 1.01 0.991 – 1.02 0.417 19359 185465 all phecode
320 Meningitis Neurological 1.07 0.972 – 1.18 0.162 444 4447 all phecode
323 Encephalitis Neurological 0.902 0.809 – 1.01 0.0637 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 0.773 0.615 – 0.971 0.0271 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 0.998 0.885 – 1.13 0.975 292 2916 all phecode
327 Sleep disorders Neurological 1.05 0.986 – 1.11 0.133 1164 11659 all phecode
327.3 Sleep apnea Neurological 0.999 0.968 – 1.03 0.945 4428 44318 all phecode
327.4 Insomnia Neurological 0.993 0.844 – 1.17 0.932 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 1 0.838 – 1.19 0.997 136 1390 all phecode
331 Other cerebral degenerations Neurological 0.929 0.875 – 0.987 0.0176 1142 11416 all phecode
331.1 Hydrocephalus Neurological 0.917 0.836 – 1 0.0635 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 0.957 0.868 – 1.06 0.379 430 4298 all phecode
332 Parkinson's disease Neurological 0.926 0.871 – 0.984 0.0136 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.01 0.94 – 1.08 0.842 894 8954 all phecode
333.1 Essential tremor Neurological 1.02 0.886 – 1.17 0.791 216 2157 all phecode
333.2 Myoclonus Neurological 0.922 0.75 – 1.13 0.441 96 958 all phecode
333.4 Torsion dystonia Neurological 1.11 0.98 – 1.27 0.0997 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 1.04 0.995 – 1.1 0.0783 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 0.931 0.771 – 1.13 0.461 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 1.04 0.911 – 1.19 0.564 245 2446 all phecode
335 Multiple sclerosis Neurological 1.07 1.01 – 1.13 0.0161 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 0.98 0.863 – 1.11 0.755 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 0.869 0.686 – 1.1 0.241 72 719 all phecode
338 Pain Neurological 1.05 0.978 – 1.14 0.169 768 7692 all phecode
338.1 Acute pain Neurological 1.05 0.947 – 1.17 0.351 394 3937 all phecode
338.2 Chronic pain Neurological 1.07 0.961 – 1.19 0.221 380 3817 all phecode
339 Other headache syndromes Neurological 0.986 0.963 – 1.01 0.236 7819 78241 all phecode
340 Migraine Neurological 1.01 0.974 – 1.05 0.531 2860 28602 all phecode
340.1 Migrain with aura Neurological 0.96 0.832 – 1.11 0.574 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.03 0.901 – 1.17 0.69 252 2535 all phecode
342 Hemiplegia Neurological 0.981 0.93 – 1.03 0.487 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 1.14 0.963 – 1.36 0.125 145 1450 all phecode
344 Other paralytic syndromes Neurological 0.955 0.881 – 1.03 0.257 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.994 0.965 – 1.02 0.665 5023 50270 all phecode
345.1 Epilepsy Neurological 0.929 0.867 – 0.995 0.0347 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 0.893 0.81 – 0.985 0.0236 439 4385 all phecode
345.12 Partial epilepsy Neurological 0.94 0.834 – 1.06 0.312 277 2776 all phecode
345.3 Convulsions Neurological 0.997 0.955 – 1.04 0.901 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.936 0.793 – 1.11 0.435 144 1438 all phecode
348 Other conditions of brain Neurological 1 0.928 – 1.08 1 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.06 0.937 – 1.21 0.344 268 2678 all phecode
348.4 Cerebral cysts Neurological 0.894 0.749 – 1.07 0.214 133 1350 all phecode
348.7 Coma Neurological 1.02 0.913 – 1.13 0.775 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 0.991 0.868 – 1.13 0.898 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 1.07 0.963 – 1.19 0.211 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.06 0.945 – 1.19 0.319 342 3414 all phecode
350 Abnormal movement Neurological 0.969 0.932 – 1.01 0.124 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 1.06 0.989 – 1.14 0.0977 887 8852 all phecode
350.2 Abnormality of gait Neurological 0.952 0.905 – 1 0.0624 1596 15969 all phecode
350.3 Lack of coordination Neurological 0.909 0.818 – 1.01 0.0789 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.17 0.87 – 1.56 0.305 54 540 all phecode
351 Other peripheral nerve disorders Neurological 0.994 0.975 – 1.01 0.496 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 0.981 0.929 – 1.04 0.5 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.957 0.871 – 1.05 0.358 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 0.993 0.927 – 1.06 0.851 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 1.02 0.963 – 1.09 0.462 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 1.08 0.894 – 1.31 0.418 114 1138 all phecode
353.2 Nerve root lesions Neurological 1.49 1.12 – 1.97 0.00577 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.753 0.641 – 0.885 0.000573 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 0.986 0.933 – 1.04 0.619 1361 13648 all phecode
358 Myoneural disorders Neurological 0.872 0.759 – 1 0.0512 211 2109 all phecode
358.1 Myasthenia gravis Neurological 0.857 0.741 – 0.991 0.0371 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 1.03 0.94 – 1.14 0.5 465 4646 all phecode
359.1 Muscular dystrophies Neurological 1.01 0.847 – 1.21 0.879 122 1219 all phecode
359.2 Myopathy Neurological 1.04 0.93 – 1.16 0.52 360 3597 all phecode
360 Disorders of the globe Sense Organs 0.94 0.838 – 1.05 0.285 337 3367 all phecode
360.2 Progressive myopia Sense Organs 0.985 0.863 – 1.13 0.826 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 1.03 0.99 – 1.06 0.162 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.02 0.965 – 1.08 0.48 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 1.02 0.801 – 1.29 0.894 68 680 all phecode
362 Other retinal disorders Sense Organs 0.999 0.966 – 1.03 0.945 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.986 0.944 – 1.03 0.538 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.986 0.944 – 1.03 0.536 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.1 0.94 – 1.29 0.231 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 1.14 0.929 – 1.39 0.21 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.02 0.95 – 1.1 0.577 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 1 0.864 – 1.17 0.962 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.866 0.697 – 1.08 0.195 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.1 0.913 – 1.33 0.313 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.991 0.846 – 1.16 0.909 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 0.949 0.746 – 1.21 0.669 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.986 0.91 – 1.07 0.733 647 6485 all phecode
364.1 Corneal opacity Sense Organs 0.996 0.805 – 1.23 0.967 90 910 all phecode
364.2 Corneal edema Sense Organs 0.805 0.645 – 1.01 0.0555 79 800 all phecode
364.4 Corneal degenerations Sense Organs 1.11 0.965 – 1.29 0.14 201 2017 all phecode
364.41 Keratoconus Sense Organs 1.26 1 – 1.59 0.0467 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 0.95 0.825 – 1.09 0.479 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 1.07 0.87 – 1.32 0.513 100 1000 all phecode
365 Glaucoma Sense Organs 0.987 0.957 – 1.02 0.419 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 0.94 0.882 – 1 0.0552 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 0.946 0.888 – 1.01 0.0877 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.95 0.879 – 1.03 0.196 698 6996 all phecode
366 Cataract Sense Organs 1.01 0.994 – 1.02 0.223 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 1.06 0.833 – 1.36 0.618 69 700 all phecode
366.2 Senile cataract Sense Organs 1.01 0.986 – 1.03 0.447 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 0.902 0.737 – 1.1 0.317 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.989 0.949 – 1.03 0.609 2408 24092 all phecode
367.1 Myopia Sense Organs 0.994 0.938 – 1.05 0.833 1251 12519 all phecode
367.2 Astigmatism Sense Organs 0.984 0.848 – 1.14 0.83 190 1899 all phecode
367.8 Hypermetropia Sense Organs 1.03 0.907 – 1.18 0.617 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 0.973 0.902 – 1.05 0.484 719 7198 all phecode
368 Visual disturbances Sense Organs 1.03 0.996 – 1.07 0.0835 2962 29648 all phecode
368.1 Amblyopia Sense Organs 1.07 0.978 – 1.17 0.142 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.09 1.01 – 1.18 0.0328 727 7288 all phecode
368.3 Anisometropia Sense Organs 0.969 0.817 – 1.15 0.72 154 1548 all phecode
368.4 Visual field defects Sense Organs 0.923 0.824 – 1.03 0.162 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 0.947 0.871 – 1.03 0.199 612 6115 all phecode
369 Infection of the eye Sense Organs 0.972 0.891 – 1.06 0.523 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 0.957 0.795 – 1.15 0.642 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 1.01 0.88 – 1.17 0.841 213 2128 all phecode
370 Keratitis Sense Organs 0.91 0.809 – 1.02 0.119 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 0.811 0.691 – 0.952 0.0105 141 1408 all phecode
371 Inflammation of the eye Sense Organs 0.999 0.962 – 1.04 0.957 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.06 0.967 – 1.17 0.206 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 0.999 0.958 – 1.04 0.98 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 1.01 0.941 – 1.09 0.721 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 0.989 0.963 – 1.02 0.444 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 0.961 0.903 – 1.02 0.212 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 0.989 0.942 – 1.04 0.641 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 0.989 0.946 – 1.03 0.607 2204 22031 all phecode
375.2 Epiphora Sense Organs 1.02 0.953 – 1.09 0.557 898 8969 all phecode
376 Disorders of the orbit Sense Organs 0.809 0.643 – 1.02 0.07 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.07 0.955 – 1.19 0.254 361 3618 all phecode
377.1 Optic atrophy Sense Organs 1.03 0.775 – 1.36 0.85 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.942 0.787 – 1.13 0.519 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.01 0.954 – 1.07 0.768 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.03 0.958 – 1.1 0.46 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.983 0.855 – 1.13 0.805 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 0.994 0.879 – 1.12 0.921 275 2755 all phecode
379 Other disorders of eye Sense Organs 0.989 0.956 – 1.02 0.507 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 0.978 0.926 – 1.03 0.428 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 1 0.955 – 1.05 0.908 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.1 0.858 – 1.42 0.439 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.04 0.941 – 1.16 0.422 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.04 0.881 – 1.22 0.676 169 1690 all phecode
380 Disorders of external ear Sense Organs 0.928 0.856 – 1.01 0.0674 642 6413 all phecode
380.1 Otitis externa Sense Organs 1.02 0.929 – 1.11 0.715 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 1.01 0.909 – 1.13 0.822 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1 0.96 – 1.05 0.861 2150 21493 all phecode
381.1 Otitis media Sense Organs 0.995 0.947 – 1.04 0.839 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.971 0.905 – 1.04 0.406 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 1.02 0.882 – 1.18 0.793 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 0.944 0.807 – 1.1 0.473 171 1709 all phecode
381.9 Otorrhea Sense Organs 1.05 0.927 – 1.19 0.448 281 2807 all phecode
382 Otalgia Sense Organs 0.977 0.869 – 1.1 0.693 308 3084 all phecode
383 Otosclerosis Sense Organs 1.03 0.912 – 1.16 0.649 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.01 0.958 – 1.07 0.634 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.01 0.946 – 1.07 0.815 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.959 0.891 – 1.03 0.261 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 0.926 0.852 – 1.01 0.0719 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.955 0.838 – 1.09 0.489 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1 0.955 – 1.05 0.879 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 1.02 0.932 – 1.11 0.726 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 0.981 0.881 – 1.09 0.721 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 1.03 0.956 – 1.11 0.431 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.984 0.954 – 1.01 0.291 4582 45806 all phecode
388 Other disorders of ear Sense Organs 1.07 0.928 – 1.24 0.342 202 2017 all phecode
389 Hearing loss Sense Organs 1.01 0.978 – 1.04 0.542 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.919 0.835 – 1.01 0.0836 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 0.965 0.877 – 1.06 0.467 450 4497 all phecode
389.4 Tinnitus Sense Organs 1.02 0.928 – 1.11 0.731 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 0.976 0.948 – 1.01 0.106 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 0.982 0.946 – 1.02 0.345 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 0.954 0.901 – 1.01 0.11 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 0.932 0.875 – 0.992 0.028 1058 10566 all phecode
395 Heart valve disorders Circulatory System 0.969 0.939 – 1 0.051 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.982 0.945 – 1.02 0.342 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.03 0.907 – 1.16 0.68 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 0.985 0.81 – 1.2 0.878 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.91 0.736 – 1.12 0.382 97 970 all phecode
395.6 Heart valve replaced Circulatory System 0.94 0.892 – 0.991 0.0219 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 1.06 0.997 – 1.13 0.0604 1048 10468 all phecode
401 Hypertension Circulatory System 0.992 0.984 – 1 0.0596 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 0.992 0.984 – 1 0.0769 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 0.974 0.929 – 1.02 0.277 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 0.946 0.852 – 1.05 0.306 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.974 0.924 – 1.03 0.324 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 0.958 0.805 – 1.14 0.627 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 0.948 0.899 – 1 0.0481 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 0.966 0.954 – 0.977 1.34e-08 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.964 0.937 – 0.992 0.0121 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 0.955 0.937 – 0.973 1.81e-06 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 0.982 0.966 – 0.999 0.0338 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 0.948 0.934 – 0.962 6.55e-13 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.948 0.878 – 1.02 0.179 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.966 0.95 – 0.982 5.09e-05 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.978 0.922 – 1.04 0.471 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 0.968 0.923 – 1.02 0.18 1823 18228 all phecode
414.2 ASCVD Circulatory System 0.928 0.735 – 1.17 0.528 72 719 all phecode
415 Pulmonary heart disease Circulatory System 1 0.973 – 1.03 0.836 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.963 0.754 – 1.23 0.763 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.91 0.837 – 0.989 0.0268 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 0.912 0.828 – 1 0.06 448 4475 all phecode
416 Cardiomegaly Circulatory System 0.984 0.945 – 1.02 0.413 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 0.994 0.982 – 1.01 0.34 28599 270106 all phecode
418.1 Precordial pain Circulatory System 1.02 0.982 – 1.05 0.339 3551 35541 all phecode
420 Carditis Circulatory System 0.982 0.939 – 1.03 0.414 2106 21053 all phecode
420.1 Myocarditis Circulatory System 0.909 0.757 – 1.09 0.307 127 1267 all phecode
420.2 Pericarditis Circulatory System 0.988 0.934 – 1.04 0.663 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 0.931 0.81 – 1.07 0.313 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 1.02 0.843 – 1.23 0.863 113 1129 all phecode
420.3 Endocarditis Circulatory System 0.98 0.908 – 1.06 0.599 719 7194 all phecode
425 Cardiomyopathy Circulatory System 1.02 0.965 – 1.09 0.439 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.02 0.965 – 1.09 0.426 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.97 0.819 – 1.15 0.723 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.05 0.898 – 1.24 0.523 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 1.11 0.853 – 1.46 0.426 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 0.982 0.958 – 1.01 0.152 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 0.991 0.948 – 1.04 0.691 2114 21162 all phecode
426.21 First degree AV block Circulatory System 0.983 0.921 – 1.05 0.612 986 9867 all phecode
426.23 Second degree AV block Circulatory System 1 0.91 – 1.11 0.955 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 0.985 0.905 – 1.07 0.726 587 5868 all phecode
426.25 Other heart block Circulatory System 0.882 0.74 – 1.05 0.164 131 1318 all phecode
426.3 Bundle branch block Circulatory System 1.01 0.972 – 1.04 0.664 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 1.01 0.961 – 1.07 0.61 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 0.996 0.948 – 1.05 0.87 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.02 0.895 – 1.16 0.757 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 0.885 0.684 – 1.14 0.35 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.94 0.902 – 0.979 0.00305 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.938 0.898 – 0.979 0.00351 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 0.982 0.969 – 0.996 0.00928 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 0.995 0.96 – 1.03 0.799 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.01 0.969 – 1.05 0.621 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.932 0.872 – 0.997 0.0396 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 0.978 0.962 – 0.995 0.0124 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.959 0.925 – 0.994 0.0237 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.01 0.956 – 1.08 0.635 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.01 0.901 – 1.12 0.913 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 1.02 0.959 – 1.09 0.489 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.962 0.9 – 1.03 0.249 952 9541 all phecode
427.6 Premature beats Circulatory System 0.98 0.896 – 1.07 0.651 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 1.12 0.924 – 1.35 0.254 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 1.03 0.982 – 1.07 0.245 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.997 0.899 – 1.11 0.958 402 4029 all phecode
427.9 Palpitations Circulatory System 0.962 0.93 – 0.994 0.0209 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.971 0.945 – 0.998 0.0351 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 0.984 0.941 – 1.03 0.475 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 0.959 0.93 – 0.989 0.0082 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 0.965 0.894 – 1.04 0.353 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 1.03 0.8 – 1.31 0.843 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.976 0.893 – 1.07 0.586 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 0.949 0.822 – 1.1 0.472 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 1 0.957 – 1.05 0.879 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.03 0.96 – 1.11 0.407 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 0.965 0.896 – 1.04 0.339 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 0.947 0.836 – 1.07 0.389 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 0.968 0.947 – 0.989 0.00337 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.954 0.899 – 1.01 0.12 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 0.926 0.812 – 1.06 0.252 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.96 0.93 – 0.99 0.0103 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.943 0.897 – 0.991 0.0215 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 0.97 0.934 – 1.01 0.116 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 0.999 0.956 – 1.04 0.98 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 1.01 0.91 – 1.12 0.881 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.01 0.95 – 1.07 0.833 1279 12783 all phecode
440 Atherosclerosis Circulatory System 0.983 0.93 – 1.04 0.535 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.02 0.844 – 1.23 0.841 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.98 0.911 – 1.05 0.581 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.04 0.925 – 1.17 0.495 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.04 0.959 – 1.13 0.332 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.08 0.953 – 1.22 0.228 283 2827 all phecode
442 Other aneurysm Circulatory System 1 0.958 – 1.05 0.85 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 0.982 0.93 – 1.04 0.497 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.995 0.93 – 1.06 0.88 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.18 0.962 – 1.45 0.113 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.06 0.905 – 1.25 0.448 169 1696 all phecode
442.4 Arterial dissection Circulatory System 1.24 0.944 – 1.63 0.121 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 0.998 0.867 – 1.15 0.983 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 0.994 0.962 – 1.03 0.736 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 0.983 0.925 – 1.04 0.571 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.942 0.848 – 1.05 0.263 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1 0.968 – 1.04 0.933 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.01 0.974 – 1.06 0.498 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 0.992 0.928 – 1.06 0.814 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.998 0.916 – 1.09 0.973 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.03 0.959 – 1.11 0.408 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 0.994 0.856 – 1.15 0.934 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 1.02 0.917 – 1.13 0.742 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 1.12 0.983 – 1.28 0.087 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 0.997 0.942 – 1.06 0.924 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 0.996 0.929 – 1.07 0.911 868 8712 all phecode
448 Disease of capillaries Circulatory System 0.992 0.834 – 1.18 0.924 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.04 0.963 – 1.13 0.314 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.998 0.966 – 1.03 0.924 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1 0.971 – 1.04 0.781 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.999 0.916 – 1.09 0.978 564 5645 all phecode
454 Varicose veins Circulatory System 0.991 0.972 – 1.01 0.344 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 0.991 0.972 – 1.01 0.358 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.988 0.91 – 1.07 0.769 624 6325 all phecode
455 Hemorrhoids Circulatory System 1.01 0.992 – 1.02 0.411 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.17 1.01 – 1.36 0.0396 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.941 0.765 – 1.16 0.567 97 967 all phecode
458 Hypotension Circulatory System 0.965 0.939 – 0.992 0.00998 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 0.934 0.883 – 0.987 0.0163 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 0.913 0.799 – 1.04 0.183 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 0.98 0.947 – 1.02 0.266 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 0.997 0.981 – 1.01 0.736 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 1.13 0.948 – 1.35 0.173 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 0.997 0.981 – 1.01 0.735 16103 159422 all phecode
464 Acute sinusitis Respiratory 0.95 0.822 – 1.1 0.487 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.04 0.992 – 1.08 0.107 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 1.05 0.978 – 1.13 0.175 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1 0.854 – 1.17 0.992 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1 0.973 – 1.03 0.837 4654 46553 all phecode
471 Nasal polyps Respiratory 0.985 0.95 – 1.02 0.404 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.946 0.886 – 1.01 0.097 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1.02 0.976 – 1.06 0.43 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 0.965 0.786 – 1.19 0.736 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.02 0.902 – 1.15 0.745 264 2647 all phecode
473.4 Voice disturbance Respiratory 0.992 0.931 – 1.06 0.796 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 1.02 0.968 – 1.07 0.508 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 1 0.918 – 1.09 0.98 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.04 0.98 – 1.11 0.186 1122 11199 all phecode
475 Chronic sinusitis Respiratory 0.987 0.948 – 1.03 0.535 2589 25882 all phecode
476 Allergic rhinitis Respiratory 1.03 0.964 – 1.09 0.401 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.05 1.01 – 1.1 0.0159 2447 24452 all phecode
478 Throat pain Respiratory 0.999 0.9 – 1.11 0.989 377 3789 all phecode
479 Other upper respiratory disease Respiratory 1.01 0.975 – 1.04 0.658 4074 40737 all phecode
480 Pneumonia Respiratory 1 0.98 – 1.02 0.981 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 1.01 0.981 – 1.03 0.634 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.01 0.979 – 1.03 0.683 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.12 0.902 – 1.39 0.305 93 929 all phecode
480.2 Viral pneumonia Respiratory 0.853 0.678 – 1.07 0.176 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.913 0.749 – 1.11 0.373 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.966 0.898 – 1.04 0.348 794 7951 all phecode
481 Influenza Respiratory 0.871 0.779 – 0.975 0.0162 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.995 0.86 – 1.15 0.95 193 1930 all phecode
495 Asthma Respiratory 1 0.988 – 1.01 0.857 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 1.07 0.936 – 1.22 0.331 250 2510 all phecode
496 Chronic airway obstruction Respiratory 1.01 0.986 – 1.03 0.576 10424 101546 all phecode
496.1 Emphysema Respiratory 0.981 0.934 – 1.03 0.46 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 1.01 0.969 – 1.05 0.722 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1 0.961 – 1.04 0.99 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 0.985 0.939 – 1.03 0.523 1885 18859 all phecode
497 Bronchitis Respiratory 1.09 1 – 1.18 0.0447 626 6267 all phecode
500 Lung disease due to external agents Respiratory 0.977 0.884 – 1.08 0.654 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.1 0.878 – 1.38 0.411 79 784 all phecode
500.2 Pneumoconiosis Respiratory 0.965 0.849 – 1.1 0.591 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.06 0.974 – 1.15 0.185 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.06 0.987 – 1.13 0.115 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 0.998 0.91 – 1.09 0.962 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.986 0.883 – 1.1 0.804 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.1 0.855 – 1.42 0.451 61 610 all phecode
506 Empyema and pneumothorax Respiratory 1.02 0.958 – 1.08 0.549 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 1.01 0.98 – 1.03 0.678 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.985 0.94 – 1.03 0.511 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.02 0.98 – 1.06 0.336 2599 26031 all phecode
509.1 Respiratory failure Respiratory 1.01 0.962 – 1.05 0.767 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 1 0.954 – 1.05 0.929 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 1.08 0.917 – 1.27 0.354 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.01 0.904 – 1.12 0.912 386 3863 all phecode
510 Other diseases of lung Respiratory 0.99 0.919 – 1.07 0.795 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 0.995 0.974 – 1.02 0.66 9031 90349 all phecode
512.1 Wheezing Respiratory 0.92 0.804 – 1.05 0.226 220 2196 all phecode
512.2 Painful respiration Respiratory 1.06 0.92 – 1.22 0.425 207 2075 all phecode
512.7 Shortness of breath Respiratory 0.978 0.952 – 1 0.101 5842 58498 all phecode
512.8 Cough Respiratory 0.997 0.959 – 1.04 0.871 2866 28642 all phecode
512.9 Other dyspnea Respiratory 1.07 1 – 1.15 0.0413 914 9124 all phecode
513 Respiratory abnormalities Respiratory 1.07 0.979 – 1.16 0.14 611 6112 all phecode
513.3 Hypoventilation Respiratory 0.936 0.752 – 1.17 0.557 83 830 all phecode
513.4 Hyperventilation Respiratory 1.15 1.02 – 1.31 0.0251 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 1.01 0.851 – 1.2 0.912 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 0.979 0.939 – 1.02 0.313 2465 24673 all phecode
516 Abnormal sputum Respiratory 1.02 0.976 – 1.07 0.365 2132 21335 all phecode
516.1 Hemoptysis Respiratory 1.02 0.974 – 1.07 0.41 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.01 0.985 – 1.03 0.556 9366 93681 all phecode
519.2 Respiratory complications Respiratory 0.993 0.888 – 1.11 0.895 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1 0.982 – 1.03 0.735 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.1 0.97 – 1.24 0.142 303 3049 all phecode
520 Disorders of tooth development Digestive 1.01 0.964 – 1.06 0.705 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.952 0.729 – 1.24 0.716 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 1.01 0.965 – 1.05 0.752 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 0.978 0.942 – 1.01 0.24 3016 30245 all phecode
521.1 Dental caries Digestive 0.974 0.938 – 1.01 0.163 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.02 0.976 – 1.08 0.331 1774 17750 all phecode
522.5 Periapical abscess Digestive 1.04 0.983 – 1.11 0.164 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 1.05 1 – 1.11 0.0513 1681 16812 all phecode
523.1 Gingivitis Digestive 1.27 1.03 – 1.55 0.0225 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.01 0.955 – 1.08 0.654 1165 11650 all phecode
523.31 Acute periodontitis Digestive 0.953 0.881 – 1.03 0.231 666 6667 all phecode
523.32 Chronic periodontitis Digestive 1.1 1.01 – 1.2 0.0313 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.922 0.824 – 1.03 0.157 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.939 0.835 – 1.06 0.289 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.986 0.948 – 1.03 0.489 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.954 0.752 – 1.21 0.694 72 720 all phecode
526 Diseases of the jaws Digestive 1.01 0.943 – 1.08 0.788 928 9279 all phecode
526.1 Cysts of the jaws Digestive 1.02 0.913 – 1.15 0.7 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.02 0.778 – 1.33 0.907 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.08 0.941 – 1.23 0.287 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.08 0.941 – 1.24 0.277 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.983 0.807 – 1.2 0.869 110 1098 all phecode
526.9 Jaw disease NOS Digestive 0.924 0.809 – 1.06 0.243 233 2329 all phecode
527 Diseases of the salivary glands Digestive 1.07 0.99 – 1.16 0.0867 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.12 0.893 – 1.42 0.318 84 838 all phecode
527.2 Sialoadenitis Digestive 1.09 0.974 – 1.22 0.134 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 0.988 0.772 – 1.27 0.926 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.05 0.863 – 1.27 0.639 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.989 0.957 – 1.02 0.518 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 1.06 0.967 – 1.17 0.208 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.11 0.998 – 1.23 0.055 389 3884 all phecode
528.12 Oral aphthae Digestive 0.881 0.709 – 1.1 0.256 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.875 0.753 – 1.02 0.0847 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 0.997 0.833 – 1.19 0.978 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 1.07 0.869 – 1.32 0.526 94 940 all phecode
528.5 Diseases of lips Digestive 0.921 0.852 – 0.995 0.0375 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 0.985 0.877 – 1.11 0.803 308 3079 all phecode
528.7 Sialolithiasis Digestive 1.03 0.921 – 1.16 0.565 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 0.995 0.938 – 1.06 0.869 1232 12312 all phecode
529.1 Glossitis Digestive 0.971 0.863 – 1.09 0.621 299 2986 all phecode
530 Diseases of esophagus Digestive 0.993 0.982 – 1 0.248 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.993 0.981 – 1 0.223 31253 272429 all phecode
530.11 GERD Digestive 0.994 0.981 – 1.01 0.423 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 1.01 0.98 – 1.04 0.584 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 0.993 0.974 – 1.01 0.519 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.997 0.948 – 1.05 0.908 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.01 0.96 – 1.06 0.779 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 0.961 0.886 – 1.04 0.344 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.08 0.906 – 1.29 0.395 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.926 0.83 – 1.03 0.168 341 3416 all phecode
530.9 Heartburn Digestive 0.979 0.936 – 1.02 0.363 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.01 0.987 – 1.04 0.356 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.987 0.91 – 1.07 0.76 637 6374 all phecode
531.2 Gastric ulcer Digestive 1 0.971 – 1.04 0.865 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 1.02 0.983 – 1.06 0.295 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.06 0.958 – 1.17 0.265 427 4268 all phecode
532 Dysphagia Digestive 0.998 0.973 – 1.02 0.908 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 0.995 0.983 – 1.01 0.428 28078 261548 all phecode
535.1 Acute gastritis Digestive 1.04 0.982 – 1.11 0.176 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 0.885 0.795 – 0.986 0.0266 370 3687 all phecode
535.6 Duodenitis Digestive 0.994 0.971 – 1.02 0.642 7592 75928 all phecode
535.8 Other specified gastritis Digestive 0.987 0.965 – 1.01 0.274 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.01 0.835 – 1.23 0.908 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.03 0.904 – 1.17 0.672 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 0.996 0.961 – 1.03 0.806 3391 33907 all phecode
540 Appendiceal conditions Digestive 0.99 0.954 – 1.03 0.588 3088 30890 all phecode
540.1 Appendicitis Digestive 0.995 0.957 – 1.03 0.777 2895 28963 all phecode
540.11 Acute appendicitis Digestive 0.999 0.96 – 1.04 0.954 2601 26019 all phecode
550 Abdominal hernia Digestive 0.995 0.985 – 1.01 0.346 45429 282640 all phecode
550.1 Inguinal hernia Digestive 0.998 0.982 – 1.02 0.842 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 0.99 0.977 – 1 0.112 26494 238953 all phecode
550.3 Femoral hernia Digestive 0.949 0.875 – 1.03 0.202 651 6504 all phecode
550.4 Umbilical hernia Digestive 1.03 0.995 – 1.07 0.0902 3705 37072 all phecode
550.5 Ventral hernia Digestive 0.985 0.951 – 1.02 0.389 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 0.99 0.96 – 1.02 0.514 4444 44442 all phecode
555.1 Regional enteritis Digestive 1 0.953 – 1.05 0.954 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 0.983 0.948 – 1.02 0.359 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.02 0.931 – 1.11 0.711 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 0.939 0.882 – 1 0.0497 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 0.946 0.875 – 1.02 0.171 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.983 0.872 – 1.11 0.78 299 2987 all phecode
557.1 Celiac disease Digestive 1 0.955 – 1.05 0.942 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 1.01 0.994 – 1.03 0.226 15492 155105 all phecode
559 Ileostomy status Digestive 0.959 0.912 – 1.01 0.103 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 0.992 0.96 – 1.03 0.634 3936 39337 all phecode
560.1 Paralytic ileus Digestive 1.11 1.01 – 1.21 0.0302 523 5231 all phecode
560.2 Impaction of intestine Digestive 0.933 0.823 – 1.06 0.275 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.961 0.894 – 1.03 0.272 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 0.98 0.946 – 1.02 0.272 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 1 0.988 – 1.02 0.635 15772 157686 all phecode
561.1 Diarrhea Digestive 1.03 0.933 – 1.13 0.587 466 4653 all phecode
561.2 Flatulence Digestive 1.03 0.983 – 1.09 0.202 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 0.999 0.986 – 1.01 0.822 26714 211692 all phecode
562.1 Diverticulosis Digestive 0.998 0.985 – 1.01 0.78 26672 211642 all phecode
563 Constipation Digestive 0.982 0.963 – 1 0.0824 10314 103140 all phecode
564 Functional digestive disorders Digestive 1 0.989 – 1.02 0.718 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 0.994 0.967 – 1.02 0.652 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.02 0.968 – 1.07 0.481 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 1 0.986 – 1.02 0.767 15186 151648 all phecode
565 Anal and rectal conditions Digestive 0.985 0.968 – 1 0.0726 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 0.975 0.952 – 0.998 0.0372 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 0.97 0.907 – 1.04 0.372 929 9293 all phecode
568 Other disorders of peritoneum Digestive 1.01 0.978 – 1.05 0.449 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1 0.967 – 1.04 0.844 3101 30987 all phecode
569 Other disorders of intestine Digestive 0.969 0.939 – 1 0.0539 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.979 0.826 – 1.16 0.81 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 0.98 0.893 – 1.08 0.674 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.05 1.01 – 1.09 0.014 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.01 0.964 – 1.07 0.598 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.838 0.695 – 1.01 0.0641 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 1.05 0.926 – 1.19 0.45 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.07 1 – 1.14 0.0494 976 9804 all phecode
571.81 Portal hypertension Digestive 1.07 0.976 – 1.17 0.151 528 5285 all phecode
572 Ascites (non malignant) Digestive 1.03 0.982 – 1.09 0.202 1544 15454 all phecode
573 Other disorders of liver Digestive 1.03 0.974 – 1.08 0.33 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 1.09 0.884 – 1.33 0.431 96 960 all phecode
573.3 Hepatomegaly Digestive 1.07 0.947 – 1.21 0.278 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 1.01 0.944 – 1.08 0.752 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 1.01 0.975 – 1.05 0.591 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 0.851 0.741 – 0.978 0.0229 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.04 1.02 – 1.05 3.7e-05 15607 156123 all phecode
574.1 Cholelithiasis Digestive 1.03 1.01 – 1.05 0.000338 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1 0.95 – 1.06 0.956 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.03 0.997 – 1.05 0.077 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 1.03 0.985 – 1.07 0.219 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.04 0.998 – 1.08 0.063 2748 27523 all phecode
575 Other biliary tract disease Digestive 1.05 1.02 – 1.09 0.00342 3867 38724 all phecode
575.1 Cholangitis Digestive 1.05 0.958 – 1.15 0.292 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 1.09 1.01 – 1.17 0.0237 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 1.1 0.996 – 1.21 0.0603 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 1 0.95 – 1.06 0.881 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 1.1 1.03 – 1.17 0.00418 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.05 0.944 – 1.18 0.344 348 3488 all phecode
577 Diseases of pancreas Digestive 1.06 1.02 – 1.11 0.00266 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 1.08 1.03 – 1.13 0.00139 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 1.07 0.972 – 1.17 0.176 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.02 0.92 – 1.14 0.67 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 0.993 0.979 – 1.01 0.33 20626 206278 all phecode
578.1 Hematemesis Digestive 1.01 0.965 – 1.06 0.647 1958 19564 all phecode
578.2 Blood in stool Digestive 0.978 0.94 – 1.02 0.287 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 0.997 0.979 – 1.01 0.732 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.988 0.961 – 1.02 0.415 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1 0.951 – 1.06 0.938 1548 15498 all phecode
579.2 Splenomegaly Digestive 1.11 1 – 1.23 0.0503 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1 0.952 – 1.05 0.96 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.958 0.909 – 1.01 0.107 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 0.981 0.921 – 1.05 0.561 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.01 0.795 – 1.28 0.95 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.09 0.918 – 1.3 0.314 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.973 0.908 – 1.04 0.428 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.958 0.872 – 1.05 0.377 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.974 0.856 – 1.11 0.684 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.953 0.84 – 1.08 0.454 253 2529 all phecode
585 Renal failure Genitourinary 0.993 0.969 – 1.02 0.597 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 0.995 0.965 – 1.03 0.763 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 0.978 0.927 – 1.03 0.406 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.99 0.951 – 1.03 0.617 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 0.968 0.883 – 1.06 0.49 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1 0.967 – 1.04 0.939 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.942 0.819 – 1.08 0.406 208 2089 all phecode
586.11 Small kidney Genitourinary 0.987 0.847 – 1.15 0.861 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.03 0.971 – 1.09 0.343 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.887 0.705 – 1.12 0.305 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.975 0.911 – 1.04 0.467 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 1.07 0.964 – 1.19 0.197 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.22 0.983 – 1.51 0.0716 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.12 0.928 – 1.35 0.238 116 1158 all phecode
590 Pyelonephritis Genitourinary 0.961 0.908 – 1.02 0.167 1328 13285 all phecode
591 Urinary tract infection Genitourinary 0.998 0.98 – 1.02 0.835 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 0.967 0.931 – 1 0.0813 2966 29661 all phecode
592.1 Cystitis Genitourinary 0.971 0.934 – 1.01 0.129 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 0.973 0.821 – 1.15 0.757 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 0.953 0.889 – 1.02 0.168 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.903 0.793 – 1.03 0.127 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.831 0.708 – 0.976 0.024 165 1662 all phecode
593 Hematuria Genitourinary 0.995 0.979 – 1.01 0.529 16068 160204 all phecode
594 Urinary calculus Genitourinary 1.01 0.982 – 1.03 0.542 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 1.01 0.976 – 1.05 0.51 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 0.95 0.882 – 1.02 0.171 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 1.02 0.975 – 1.06 0.435 2401 24024 all phecode
594.8 Renal colic Genitourinary 1 0.956 – 1.05 0.987 2050 20500 all phecode
595 Hydronephrosis Genitourinary 1 0.956 – 1.05 0.945 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 0.99 0.969 – 1.01 0.334 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 1.01 0.962 – 1.06 0.744 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 0.972 0.925 – 1.02 0.275 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.998 0.966 – 1.03 0.899 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.01 0.97 – 1.04 0.755 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 0.916 0.731 – 1.15 0.445 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 0.997 0.963 – 1.03 0.857 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.04 0.92 – 1.16 0.563 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.991 0.976 – 1.01 0.223 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 0.954 0.814 – 1.12 0.566 166 1670 all phecode
599.2 Retention of urine Genitourinary 0.972 0.948 – 0.996 0.0249 6718 67168 all phecode
599.3 Dysuria Genitourinary 0.983 0.926 – 1.04 0.571 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 0.987 0.966 – 1.01 0.245 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 0.967 0.936 – 0.999 0.0404 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 0.931 0.765 – 1.13 0.48 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.13 0.879 – 1.46 0.336 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 1.03 0.983 – 1.08 0.204 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 0.998 0.978 – 1.02 0.826 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.96 0.918 – 1 0.0753 2081 20818 all phecode
601.1 Prostatitis Genitourinary 0.95 0.902 – 1 0.0522 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 0.927 0.813 – 1.06 0.257 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 0.982 0.918 – 1.05 0.6 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 0.828 0.63 – 1.09 0.177 59 588 all phecode
601.4 Balanoposthitis Genitourinary 0.917 0.814 – 1.03 0.153 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.02 0.909 – 1.15 0.729 303 3019 all phecode
602 Other disorders of prostate Genitourinary 1.01 0.951 – 1.07 0.815 1341 13408 all phecode
603 Other disorders of testis Genitourinary 0.957 0.915 – 1 0.0512 2150 21512 all phecode
603.1 Hydrocele Genitourinary 0.972 0.919 – 1.03 0.326 1339 13402 all phecode
604 Disorders of penis Genitourinary 0.97 0.936 – 1.01 0.0987 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.974 0.936 – 1.01 0.187 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.05 0.931 – 1.19 0.408 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 0.974 0.936 – 1.01 0.176 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.957 0.831 – 1.1 0.538 214 2138 all phecode
609.1 Infertility, male Genitourinary 1.03 0.79 – 1.34 0.84 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.93 0.797 – 1.09 0.361 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 1.01 0.964 – 1.05 0.806 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 0.968 0.905 – 1.04 0.345 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.07 0.95 – 1.2 0.275 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 1.08 0.962 – 1.22 0.187 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 1.02 0.964 – 1.08 0.504 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.988 0.914 – 1.07 0.762 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.991 0.941 – 1.04 0.741 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 1.04 0.798 – 1.35 0.775 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 0.985 0.934 – 1.04 0.561 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.1 1.03 – 1.18 0.00632 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.09 1.02 – 1.17 0.0127 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 1.08 0.859 – 1.37 0.495 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 1.03 0.974 – 1.08 0.335 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.03 0.958 – 1.12 0.387 720 7210 all phecode
613.5 Mastodynia Genitourinary 1.01 0.803 – 1.28 0.915 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 1.01 0.932 – 1.09 0.848 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 0.963 0.859 – 1.08 0.521 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 1.01 0.877 – 1.17 0.858 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.998 0.972 – 1.03 0.898 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.986 0.947 – 1.03 0.495 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.985 0.918 – 1.06 0.683 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.03 0.79 – 1.34 0.835 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.994 0.899 – 1.1 0.903 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.92 0.825 – 1.03 0.132 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.99 0.878 – 1.12 0.87 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.01 0.975 – 1.06 0.472 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.02 0.96 – 1.07 0.585 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.05 0.952 – 1.16 0.327 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.03 0.958 – 1.11 0.403 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.889 0.786 – 1.01 0.0631 274 2737 all phecode
615 Endometriosis Genitourinary 0.985 0.954 – 1.02 0.358 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 0.975 0.866 – 1.1 0.671 304 3037 all phecode
618 Genital prolapse Genitourinary 0.992 0.973 – 1.01 0.388 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 0.984 0.96 – 1.01 0.175 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.01 0.98 – 1.04 0.578 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.913 0.834 – 0.999 0.0485 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.01 0.932 – 1.09 0.83 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 1 0.982 – 1.03 0.723 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.971 0.901 – 1.05 0.443 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1.01 0.971 – 1.04 0.724 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.02 0.982 – 1.06 0.304 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.986 0.94 – 1.04 0.581 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.998 0.944 – 1.06 0.949 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 1.04 0.82 – 1.32 0.738 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 1.06 0.996 – 1.13 0.0658 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 1 0.982 – 1.02 0.82 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 1 0.982 – 1.03 0.678 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 1 0.965 – 1.04 0.98 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.02 0.964 – 1.08 0.477 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 0.968 0.9 – 1.04 0.387 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.917 0.803 – 1.05 0.2 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.997 0.904 – 1.1 0.956 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 0.99 0.964 – 1.02 0.46 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.976 0.94 – 1.01 0.217 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 0.918 0.865 – 0.973 0.00436 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.997 0.98 – 1.01 0.689 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.989 0.971 – 1.01 0.198 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 1.07 0.881 – 1.31 0.485 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 0.974 0.954 – 0.994 0.0117 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 1.01 0.962 – 1.05 0.756 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 1 0.97 – 1.04 0.87 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 0.985 0.938 – 1.03 0.545 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.987 0.841 – 1.16 0.871 159 1587 all phecode
626.8 Infertility, female Genitourinary 1.01 0.953 – 1.07 0.777 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.02 0.995 – 1.04 0.145 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 1.01 0.991 – 1.04 0.239 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 1.09 0.932 – 1.27 0.283 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.02 0.959 – 1.08 0.539 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 1.01 0.897 – 1.13 0.897 310 3097 all phecode
628 Ovarian cyst Genitourinary 0.989 0.96 – 1.02 0.473 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.01 0.98 – 1.04 0.554 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.04 0.975 – 1.1 0.257 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.991 0.887 – 1.11 0.877 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.972 0.928 – 1.02 0.225 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.977 0.912 – 1.05 0.502 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.982 0.927 – 1.04 0.536 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1 0.959 – 1.04 0.972 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 1.04 0.962 – 1.13 0.297 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.99 0.931 – 1.05 0.755 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 1.36 1.05 – 1.76 0.0189 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.998 0.938 – 1.06 0.938 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.01 0.897 – 1.13 0.878 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.886 0.774 – 1.01 0.0808 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.927 0.786 – 1.09 0.362 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 1 0.948 – 1.06 0.88 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.988 0.946 – 1.03 0.587 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.01 0.787 – 1.3 0.937 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.955 0.847 – 1.08 0.447 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.849 0.696 – 1.04 0.107 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.04 0.895 – 1.21 0.613 193 1922 all phecode
650 Normal delivery Pregnancy Complications 0.976 0.932 – 1.02 0.316 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 1.12 1 – 1.25 0.0448 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.994 0.947 – 1.04 0.826 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.02 0.965 – 1.08 0.488 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 0.896 0.712 – 1.13 0.348 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1 0.969 – 1.03 0.964 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.927 0.763 – 1.13 0.447 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.991 0.949 – 1.04 0.697 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 1.04 0.949 – 1.13 0.419 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.985 0.956 – 1.01 0.318 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.02 0.977 – 1.06 0.386 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.13 0.954 – 1.33 0.161 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.05 0.922 – 1.19 0.47 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.847 0.665 – 1.08 0.181 63 624 all phecode
679 Complications of in utero procedures Dermatologic 0.998 0.764 – 1.3 0.986 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.02 0.996 – 1.05 0.0994 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.976 0.896 – 1.06 0.579 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.972 0.889 – 1.06 0.533 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.02 0.996 – 1.05 0.0945 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.02 0.996 – 1.05 0.0875 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.02 0.995 – 1.05 0.107 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 0.979 0.9 – 1.06 0.614 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.02 0.967 – 1.08 0.437 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 0.98 0.939 – 1.02 0.364 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 0.953 0.876 – 1.04 0.27 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 1.03 0.921 – 1.15 0.632 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1 0.917 – 1.09 0.977 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.02 0.971 – 1.06 0.512 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 0.93 0.823 – 1.05 0.243 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 1.08 0.889 – 1.32 0.426 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 0.989 0.952 – 1.03 0.588 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.01 0.982 – 1.04 0.513 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 1.29 1.01 – 1.64 0.043 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 1.22 0.927 – 1.61 0.155 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 1.08 0.895 – 1.3 0.423 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 1.03 0.961 – 1.1 0.434 986 9854 all phecode
694.1 Vitiligo Dermatologic 1.1 0.841 – 1.45 0.474 60 599 all phecode
694.2 Other dyschromia Dermatologic 1.03 0.956 – 1.11 0.438 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 0.954 0.786 – 1.16 0.63 117 1170 all phecode
695 Erythematous conditions Dermatologic 1.01 0.964 – 1.05 0.808 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 1.13 0.923 – 1.37 0.243 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 0.854 0.718 – 1.02 0.0753 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 0.751 0.573 – 0.984 0.038 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.927 0.731 – 1.17 0.529 73 727 all phecode
695.3 Rosacea Dermatologic 0.975 0.867 – 1.1 0.68 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 0.972 0.88 – 1.07 0.581 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.82 0.686 – 0.98 0.0293 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.02 0.91 – 1.13 0.783 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 1.03 0.954 – 1.11 0.482 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 0.922 0.81 – 1.05 0.221 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 0.902 0.72 – 1.13 0.371 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.07 0.973 – 1.18 0.157 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 1 0.962 – 1.05 0.829 2252 22509 all phecode
696.4 Psoriasis Dermatologic 0.999 0.956 – 1.04 0.973 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.02 0.966 – 1.07 0.552 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 0.971 0.899 – 1.05 0.453 706 7052 all phecode
697 Sarcoidosis Dermatologic 1.02 0.928 – 1.11 0.739 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 0.921 0.856 – 0.991 0.0286 782 7814 all phecode
700 Corns and callosities Dermatologic 0.888 0.789 – 0.999 0.0481 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.986 0.957 – 1.02 0.366 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 1.07 0.864 – 1.33 0.522 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.974 0.934 – 1.02 0.226 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 0.907 0.705 – 1.17 0.447 61 610 all phecode
701.4 Keloid scar Dermatologic 1.02 0.887 – 1.18 0.767 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 0.944 0.858 – 1.04 0.243 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 0.802 0.659 – 0.978 0.029 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.989 0.962 – 1.02 0.442 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 0.962 0.924 – 1 0.0613 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 1.02 0.98 – 1.06 0.363 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 0.986 0.885 – 1.1 0.798 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 0.986 0.923 – 1.05 0.674 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 1 0.974 – 1.03 0.888 5267 52727 all phecode
704.1 Alopecia Dermatologic 1.01 0.84 – 1.22 0.897 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.899 0.711 – 1.14 0.376 76 759 all phecode
705 Disorders of sweat glands Dermatologic 1.03 0.9 – 1.18 0.665 228 2287 all phecode
705.3 Hidradenitis Dermatologic 1.03 0.885 – 1.2 0.702 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 1.04 0.955 – 1.13 0.372 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 1.01 0.99 – 1.04 0.281 8317 83195 all phecode
706.1 Acne Dermatologic 1.09 0.869 – 1.37 0.448 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 1.01 0.988 – 1.03 0.382 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 0.98 0.936 – 1.03 0.395 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 0.969 0.905 – 1.04 0.357 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.986 0.952 – 1.02 0.42 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 0.956 0.874 – 1.05 0.322 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 0.976 0.837 – 1.14 0.757 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.11 0.863 – 1.42 0.422 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.999 0.96 – 1.04 0.963 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.993 0.913 – 1.08 0.871 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 1 0.919 – 1.09 0.944 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.864 0.744 – 1 0.0541 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.03 0.927 – 1.14 0.602 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.01 0.917 – 1.12 0.781 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 0.998 0.891 – 1.12 0.976 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 0.907 0.729 – 1.13 0.382 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.91 0.773 – 1.07 0.252 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.1 0.858 – 1.41 0.457 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.01 0.984 – 1.04 0.382 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.01 0.98 – 1.04 0.479 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.01 0.96 – 1.06 0.71 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.02 0.834 – 1.24 0.877 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.02 0.94 – 1.11 0.615 618 6177 all phecode
716 Other arthropathies Musculoskeletal 0.998 0.987 – 1.01 0.678 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.994 0.96 – 1.03 0.747 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.997 0.981 – 1.01 0.742 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 0.997 0.986 – 1.01 0.537 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.969 0.911 – 1.03 0.305 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 1.02 0.982 – 1.05 0.374 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1 0.977 – 1.02 0.982 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.01 0.977 – 1.03 0.723 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.05 0.9 – 1.22 0.553 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 0.941 0.845 – 1.05 0.274 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 1 0.982 – 1.03 0.752 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.982 0.896 – 1.08 0.705 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.01 0.972 – 1.05 0.621 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 0.871 0.687 – 1.1 0.254 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.02 0.989 – 1.05 0.209 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 1.06 0.966 – 1.16 0.22 517 5173 all phecode
723.1 Torticollis Musculoskeletal 1.07 0.871 – 1.3 0.535 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.02 0.972 – 1.06 0.464 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.07 0.967 – 1.19 0.19 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 1.06 0.955 – 1.17 0.287 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.05 0.814 – 1.36 0.7 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 0.998 0.949 – 1.05 0.949 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.01 0.989 – 1.02 0.5 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 1.01 0.989 – 1.03 0.351 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 0.943 0.843 – 1.05 0.301 334 3336 all phecode
726.3 Bursitis Musculoskeletal 1.01 0.944 – 1.09 0.723 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1 0.978 – 1.03 0.893 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.998 0.96 – 1.04 0.932 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 0.926 0.762 – 1.13 0.444 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.994 0.958 – 1.03 0.763 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 0.99 0.91 – 1.08 0.809 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.993 0.891 – 1.11 0.9 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.08 0.906 – 1.28 0.394 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.955 0.923 – 0.987 0.00697 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.08 0.976 – 1.2 0.136 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 0.949 0.918 – 0.981 0.00206 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.948 0.915 – 0.981 0.00238 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.01 0.98 – 1.03 0.633 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.995 0.932 – 1.06 0.885 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 1.06 0.864 – 1.29 0.586 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.984 0.868 – 1.11 0.795 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.975 0.858 – 1.11 0.7 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 0.992 0.902 – 1.09 0.865 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.06 0.92 – 1.22 0.417 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.777 0.597 – 1.01 0.0615 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.04 0.994 – 1.1 0.0872 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 0.96 0.854 – 1.08 0.492 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.898 0.822 – 0.981 0.0176 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 0.86 0.719 – 1.03 0.0976 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.01 0.955 – 1.07 0.68 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 1.08 0.895 – 1.3 0.422 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 1.01 0.993 – 1.04 0.184 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 1.08 0.925 – 1.25 0.339 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 1.01 0.985 – 1.04 0.349 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.01 0.965 – 1.06 0.627 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 1.03 0.976 – 1.08 0.294 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.02 0.998 – 1.05 0.0665 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 1.01 0.963 – 1.07 0.598 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.03 0.908 – 1.18 0.607 248 2476 all phecode
737 Curvature of spine Musculoskeletal 0.952 0.896 – 1.01 0.117 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.951 0.893 – 1.01 0.12 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.02 0.969 – 1.06 0.513 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.988 0.937 – 1.04 0.652 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 1.01 0.919 – 1.11 0.836 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 1 0.991 – 1.02 0.584 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.01 0.999 – 1.03 0.0669 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.02 1 – 1.05 0.0276 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1 0.898 – 1.12 0.962 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.99 0.912 – 1.08 0.814 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.992 0.973 – 1.01 0.378 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1 0.968 – 1.04 0.929 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 1.11 0.908 – 1.36 0.308 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 0.933 0.859 – 1.01 0.0961 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 1.23 1.04 – 1.46 0.0149 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 0.983 0.93 – 1.04 0.534 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 1.07 0.888 – 1.29 0.474 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 1 0.763 – 1.32 0.975 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.02 0.983 – 1.06 0.285 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 1.11 0.996 – 1.24 0.06 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.989 0.803 – 1.22 0.915 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 0.993 0.905 – 1.09 0.881 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 1.02 0.973 – 1.07 0.424 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.993 0.97 – 1.02 0.579 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 0.994 0.969 – 1.02 0.654 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.993 0.965 – 1.02 0.596 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1 0.918 – 1.1 0.927 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 1.02 0.934 – 1.12 0.618 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.984 0.915 – 1.06 0.659 815 8144 all phecode
745 Pain in joint Musculoskeletal 0.991 0.969 – 1.01 0.452 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.984 0.946 – 1.02 0.407 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.984 0.945 – 1.02 0.434 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.969 0.89 – 1.06 0.475 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.04 0.906 – 1.19 0.6 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.988 0.942 – 1.04 0.624 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.93 0.796 – 1.09 0.361 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.13 0.841 – 1.53 0.412 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.958 0.851 – 1.08 0.474 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.993 0.918 – 1.07 0.86 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.951 0.85 – 1.06 0.38 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.97 0.838 – 1.12 0.679 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.984 0.881 – 1.1 0.772 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.06 0.92 – 1.22 0.422 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.893 0.739 – 1.08 0.244 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.02 0.97 – 1.08 0.415 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.996 0.922 – 1.08 0.927 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.994 0.902 – 1.1 0.904 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.02 0.891 – 1.17 0.764 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.03 0.955 – 1.1 0.492 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 1 0.909 – 1.11 0.938 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.01 0.899 – 1.13 0.901 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.975 0.871 – 1.09 0.666 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 0.949 0.834 – 1.08 0.428 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 0.908 0.788 – 1.05 0.184 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.08 0.852 – 1.36 0.538 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.983 0.828 – 1.17 0.841 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.99 0.793 – 1.24 0.928 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.965 0.796 – 1.17 0.713 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.931 0.843 – 1.03 0.157 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.914 0.796 – 1.05 0.203 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.957 0.816 – 1.12 0.59 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.859 0.706 – 1.04 0.127 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.08 0.991 – 1.18 0.0804 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.995 0.792 – 1.25 0.963 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.09 0.988 – 1.2 0.0847 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.17 0.985 – 1.38 0.0743 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.13 0.88 – 1.46 0.329 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.01 0.882 – 1.16 0.856 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.967 0.791 – 1.18 0.748 96 959 all phecode
760 Back pain Symptoms 0.995 0.976 – 1.01 0.599 11126 111353 all phecode
761 Cervicalgia Symptoms 1.03 0.983 – 1.08 0.208 1791 17901 all phecode
764 Sciatica Symptoms 0.991 0.951 – 1.03 0.689 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.05 0.993 – 1.12 0.0857 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 0.929 0.856 – 1.01 0.079 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.986 0.92 – 1.06 0.698 870 8687 all phecode
771.1 Swelling of limb Symptoms 1 0.975 – 1.04 0.766 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 1 0.925 – 1.09 0.955 659 6581 all phecode
773 Pain in limb Symptoms 0.992 0.966 – 1.02 0.548 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 0.99 0.849 – 1.15 0.895 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.02 0.97 – 1.07 0.488 1870 18715 all phecode
782.3 Edema Symptoms 1.01 0.96 – 1.06 0.693 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 1.15 0.984 – 1.34 0.0789 175 1748 all phecode
783 Fever of unknown origin Symptoms 1 0.97 – 1.04 0.876 3911 39105 all phecode
785 Abdominal pain Symptoms 0.998 0.988 – 1.01 0.701 40080 301686 all phecode
788 Syncope and collapse Symptoms 0.988 0.966 – 1.01 0.257 9069 90813 all phecode
789 Nausea and vomiting Symptoms 1 0.984 – 1.02 0.722 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.05 0.893 – 1.24 0.533 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 0.869 0.7 – 1.08 0.204 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.02 0.995 – 1.05 0.108 6357 63635 all phecode
791 Gangrene Symptoms 0.99 0.907 – 1.08 0.813 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1.13 0.912 – 1.39 0.27 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.994 0.83 – 1.19 0.944 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.01 0.926 – 1.1 0.855 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.01 0.833 – 1.23 0.916 120 1198 all phecode
797 Shock Symptoms 1.07 0.907 – 1.26 0.416 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 1.06 0.866 – 1.3 0.571 102 1020 all phecode
798 Malaise and fatigue Symptoms 0.963 0.93 – 0.997 0.0356 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 0.983 0.905 – 1.07 0.684 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 1.01 0.984 – 1.03 0.505 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.03 0.98 – 1.08 0.251 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.936 0.8 – 1.09 0.406 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.99 0.947 – 1.04 0.665 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 0.925 0.859 – 0.996 0.0392 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.983 0.94 – 1.03 0.429 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 0.971 0.926 – 1.02 0.235 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.987 0.914 – 1.07 0.744 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.991 0.969 – 1.01 0.439 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 0.99 0.942 – 1.04 0.686 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.98 0.952 – 1.01 0.162 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.02 0.963 – 1.07 0.564 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 1.01 0.972 – 1.04 0.692 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.998 0.944 – 1.06 0.948 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 1 0.931 – 1.08 0.959 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.01 0.952 – 1.07 0.79 1300 12998 all phecode
817 Concussion Injuries & Poisonings 0.87 0.764 – 0.99 0.0353 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.979 0.895 – 1.07 0.642 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.02 0.983 – 1.06 0.283 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 0.977 0.929 – 1.03 0.366 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 1.04 0.996 – 1.09 0.0747 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 1.01 0.993 – 1.03 0.28 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 0.928 0.85 – 1.01 0.101 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 1.01 0.92 – 1.11 0.822 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.987 0.96 – 1.02 0.382 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.05 0.887 – 1.24 0.565 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 0.939 0.857 – 1.03 0.175 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.996 0.95 – 1.05 0.878 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.962 0.908 – 1.02 0.188 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.02 0.984 – 1.06 0.273 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.02 0.985 – 1.06 0.245 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 0.846 0.664 – 1.08 0.179 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.994 0.96 – 1.03 0.74 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.971 0.857 – 1.1 0.64 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.953 0.825 – 1.1 0.519 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1 0.965 – 1.04 0.902 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.957 0.834 – 1.1 0.535 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 1.07 0.84 – 1.37 0.578 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.03 0.998 – 1.06 0.0687 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.88 0.664 – 1.17 0.375 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.01 0.823 – 1.25 0.891 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.942 0.808 – 1.1 0.446 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 1.01 0.925 – 1.11 0.756 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 1.02 0.893 – 1.17 0.758 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 0.927 0.79 – 1.09 0.357 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 0.983 0.831 – 1.16 0.844 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 0.996 0.941 – 1.05 0.903 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 0.985 0.955 – 1.02 0.357 4260 42663 all phecode
916 Contusion Injuries & Poisonings 1.02 0.962 – 1.07 0.572 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.878 0.756 – 1.02 0.0917 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.981 0.884 – 1.09 0.719 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.997 0.876 – 1.13 0.963 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.01 0.967 – 1.06 0.61 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.921 0.804 – 1.06 0.238 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.03 0.845 – 1.26 0.768 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.04 0.952 – 1.13 0.389 550 5509 all phecode
947 Urticaria Injuries & Poisonings 0.996 0.896 – 1.11 0.945 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 0.984 0.887 – 1.09 0.759 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.02 0.926 – 1.13 0.648 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.967 0.855 – 1.09 0.594 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.9 0.822 – 0.985 0.0216 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 0.948 0.725 – 1.24 0.695 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.911 0.723 – 1.15 0.431 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.996 0.981 – 1.01 0.6 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.997 0.981 – 1.01 0.729 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 0.957 0.866 – 1.06 0.385 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.98 0.914 – 1.05 0.569 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.05 0.945 – 1.17 0.358 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.943 – 1.17 0.367 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.01 0.877 – 1.15 0.93 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.921 0.816 – 1.04 0.187 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.906 0.801 – 1.02 0.115 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.01 0.983 – 1.04 0.478 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.03 0.968 – 1.1 0.349 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.994 0.904 – 1.09 0.9 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.953 0.86 – 1.05 0.352 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.997 0.91 – 1.09 0.946 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.992 0.911 – 1.08 0.849 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.01 0.965 – 1.06 0.653 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.929 0.799 – 1.08 0.336 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.948 0.838 – 1.07 0.4 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.03 0.82 – 1.3 0.794 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.02 0.845 – 1.24 0.812 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.848 0.691 – 1.04 0.115 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.07 0.83 – 1.38 0.597 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.907 0.696 – 1.18 0.473 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.999 0.875 – 1.14 0.99 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.04 0.96 – 1.12 0.345 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.07 0.919 – 1.24 0.395 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 0.967 0.746 – 1.25 0.801 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 0.99 0.81 – 1.21 0.922 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.889 0.735 – 1.08 0.227 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.834 0.673 – 1.03 0.0943 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.02 0.982 – 1.06 0.322 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.03 0.99 – 1.07 0.145 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 1.03 0.99 – 1.07 0.145 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 0.976 0.95 – 1 0.0769 5731 64592 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 0.977 0.93 – 1.03 0.351 1738 19769 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.996 0.894 – 1.11 0.941 359 4754 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 0.915 0.84 – 0.997 0.0415 551 6302 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 0.806 0.584 – 1.11 0.188 37 398 exclusion phecode
010 Tuberculosis Infectious Diseases 1 0.808 – 1.24 1 87 1240 exclusion phecode
038 Septicemia Infectious Diseases 1.01 0.965 – 1.05 0.776 2439 30743 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.06 0.965 – 1.16 0.224 498 6342 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 0.935 0.829 – 1.05 0.269 287 3627 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 0.958 0.935 – 0.981 0.000402 7305 88434 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 0.945 0.9 – 0.991 0.021 1775 23049 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 0.984 0.923 – 1.05 0.621 1010 12203 exclusion phecode
041.4 E. coli Infectious Diseases 0.939 0.893 – 0.987 0.0142 1618 19968 exclusion phecode
053 Herpes zoster Infectious Diseases 0.962 0.844 – 1.1 0.563 238 2984 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.917 0.72 – 1.17 0.486 65 673 exclusion phecode
054 Herpes simplex Infectious Diseases 0.995 0.847 – 1.17 0.947 145 1576 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.02 0.922 – 1.13 0.694 401 4448 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.01 0.74 – 1.39 0.928 44 518 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.989 0.797 – 1.23 0.919 88 1018 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 0.934 0.807 – 1.08 0.359 190 1935 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 0.957 0.819 – 1.12 0.581 170 1992 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 0.945 0.83 – 1.08 0.395 242 3156 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.03 0.84 – 1.27 0.769 98 1133 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.03 0.822 – 1.3 0.784 79 911 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.993 0.92 – 1.07 0.864 700 7481 exclusion phecode
079 Viral infection Infectious Diseases 0.963 0.919 – 1.01 0.12 1876 20271 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.896 0.68 – 1.18 0.436 50 494 exclusion phecode
080 Postoperative infection Infectious Diseases 0.94 0.904 – 0.978 0.00233 2635 32854 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 0.988 0.935 – 1.04 0.665 1368 18158 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.17 0.875 – 1.57 0.287 48 540 exclusion phecode
1000 Burns Injuries & Poisonings 0.976 0.881 – 1.08 0.641 398 4303 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 0.97 0.903 – 1.04 0.408 836 8904 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 0.994 0.961 – 1.03 0.714 3753 39747 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.04 0.893 – 1.2 0.633 190 2203 exclusion phecode
1005 Other symptoms Injuries & Poisonings 0.989 0.923 – 1.06 0.759 862 10588 exclusion phecode
1006 Crushing injury Injuries & Poisonings 1.09 0.932 – 1.26 0.292 187 1909 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 0.949 0.81 – 1.11 0.518 169 1931 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 0.986 0.914 – 1.06 0.709 721 7581 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 0.975 0.95 – 1 0.0605 5959 63253 exclusion phecode
1010 Other tests Injuries & Poisonings 0.989 0.957 – 1.02 0.492 3890 43358 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.981 0.955 – 1.01 0.174 5682 66938 exclusion phecode
1012 Late effect Injuries & Poisonings 1.05 0.822 – 1.34 0.702 69 781 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.02 0.879 – 1.18 0.823 193 2326 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.935 0.72 – 1.22 0.615 54 498 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 0.942 0.905 – 0.981 0.00362 2557 30904 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 0.979 0.96 – 0.999 0.0377 10739 117152 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.06 0.912 – 1.24 0.43 179 2139 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 1.08 0.923 – 1.26 0.337 175 2094 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.17 0.887 – 1.53 0.269 57 578 exclusion phecode
110.12 Althete's foot Infectious Diseases 0.99 0.794 – 1.23 0.925 82 1095 exclusion phecode
112 Candidiasis Infectious Diseases 0.936 0.884 – 0.99 0.0204 1296 15509 exclusion phecode
117 Mycoses Infectious Diseases 0.96 0.81 – 1.14 0.635 141 1974 exclusion phecode
117.4 Aspergillosis Infectious Diseases 0.963 0.772 – 1.2 0.737 79 1192 exclusion phecode
130 Spirochetal infection Infectious Diseases 1.1 0.851 – 1.41 0.474 61 593 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 1.08 0.82 – 1.43 0.58 52 534 exclusion phecode
134 Helminthiases Infectious Diseases 0.925 0.737 – 1.16 0.501 81 946 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 0.842 0.66 – 1.07 0.165 67 801 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.943 0.786 – 1.13 0.527 123 1487 exclusion phecode
145 Cancer of mouth Neoplasms 1.04 0.941 – 1.15 0.443 433 4710 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.13 0.978 – 1.31 0.0961 210 2285 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.96 0.756 – 1.22 0.739 74 774 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.3 0.879 – 1.91 0.19 31 390 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.916 0.828 – 1.01 0.0903 394 4731 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 0.918 0.784 – 1.07 0.285 165 1863 exclusion phecode
149.4 Cancer of larynx Neoplasms 0.894 0.76 – 1.05 0.174 151 1958 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 0.731 0.537 – 0.995 0.0466 40 400 exclusion phecode
150 Cancer of esophagus Neoplasms 1.04 0.95 – 1.14 0.391 509 5547 exclusion phecode
151 Cancer of stomach Neoplasms 1.01 0.912 – 1.13 0.788 372 4176 exclusion phecode
153 Colorectal cancer Neoplasms 0.95 0.916 – 0.985 0.00602 3088 33642 exclusion phecode
153.2 Colon cancer Neoplasms 0.945 0.904 – 0.988 0.0127 2106 22767 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.983 0.931 – 1.04 0.529 1445 15934 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.976 0.854 – 1.11 0.718 234 2900 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.895 0.721 – 1.11 0.315 88 1137 exclusion phecode
157 Pancreatic cancer Neoplasms 0.968 0.879 – 1.07 0.502 435 4779 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.05 0.971 – 1.13 0.237 730 7811 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.959 0.928 – 0.991 0.0137 3733 40686 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.994 0.824 – 1.2 0.95 117 1380 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.11 0.924 – 1.34 0.257 117 1496 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.885 0.741 – 1.06 0.173 131 1368 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 1.07 0.767 – 1.49 0.692 37 446 exclusion phecode
165 Cancer within the respiratory system Neoplasms 0.953 0.906 – 1 0.0658 1571 20411 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 0.96 0.905 – 1.02 0.171 1195 16094 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 0.974 0.869 – 1.09 0.656 308 3198 exclusion phecode
170.1 Bone cancer Neoplasms 0.903 0.732 – 1.12 0.344 90 968 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1 0.879 – 1.14 0.993 237 2433 exclusion phecode
172 Skin cancer Neoplasms 0.982 0.962 – 1 0.0926 9913 97970 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.01 0.963 – 1.06 0.715 1998 19595 exclusion phecode
172.11 Melanomas of skin Neoplasms 1.01 0.966 – 1.06 0.616 2020 19816 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.976 0.954 – 0.999 0.0417 8041 79743 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 1.09 0.992 – 1.2 0.0739 484 4836 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.866 0.731 – 1.03 0.0953 134 1352 exclusion phecode
174 Breast cancer Neoplasms 0.997 0.975 – 1.02 0.757 8723 90287 exclusion phecode
174.1 Breast cancer [female] Neoplasms 0.999 0.977 – 1.02 0.938 8573 88773 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.999 0.976 – 1.02 0.906 8067 83652 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.907 0.72 – 1.14 0.403 77 828 exclusion phecode
175 Acquired absence of breast Neoplasms 1.02 0.966 – 1.07 0.521 1608 17209 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 0.997 0.947 – 1.05 0.903 1567 15945 exclusion phecode
180.1 Cervical cancer Neoplasms 0.961 0.83 – 1.11 0.597 179 1979 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1 0.949 – 1.05 0.991 1505 15222 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.976 0.906 – 1.05 0.519 753 9118 exclusion phecode
184 Cancer of other female genital organs Neoplasms 0.976 0.912 – 1.04 0.483 899 9797 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.956 0.882 – 1.04 0.267 637 6864 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.948 0.874 – 1.03 0.197 616 6679 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.07 0.917 – 1.24 0.401 193 2189 exclusion phecode
185 Cancer of prostate Neoplasms 1.04 1 – 1.07 0.0253 4399 43714 exclusion phecode
187 Cancer of other male genital organs Neoplasms 0.874 0.782 – 0.977 0.0176 325 3371 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.782 0.576 – 1.06 0.115 47 524 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.939 0.816 – 1.08 0.381 208 2207 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.949 0.764 – 1.18 0.639 83 813 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.01 0.971 – 1.05 0.626 2765 30510 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.975 0.9 – 1.06 0.528 665 7881 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.974 0.898 – 1.06 0.533 640 7557 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.881 0.646 – 1.2 0.424 38 478 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.01 0.961 – 1.06 0.683 1640 17725 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1 0.951 – 1.06 0.891 1447 15786 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.01 0.829 – 1.24 0.898 99 1060 exclusion phecode
190 Cancer of eye Neoplasms 0.896 0.742 – 1.08 0.251 120 1268 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.978 0.891 – 1.07 0.646 474 5040 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 1.02 0.919 – 1.13 0.727 398 4126 exclusion phecode
191.11 Cancer of brain Neoplasms 1.02 0.919 – 1.14 0.684 369 3815 exclusion phecode
193 Thyroid cancer Neoplasms 1.08 0.94 – 1.23 0.284 234 2592 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 0.83 0.647 – 1.07 0.145 58 693 exclusion phecode
195 Cancer, suspected or other Neoplasms 0.994 0.975 – 1.01 0.542 11596 121904 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 0.995 0.976 – 1.01 0.628 11093 117422 exclusion phecode
197 Chemotherapy Neoplasms 0.984 0.967 – 1 0.0768 13791 156581 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 0.986 0.96 – 1.01 0.28 6135 69612 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.977 0.944 – 1.01 0.181 3564 39028 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.02 0.962 – 1.07 0.556 1384 16689 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.03 0.964 – 1.1 0.378 970 11198 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 0.983 0.935 – 1.03 0.495 1645 19517 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.969 0.888 – 1.06 0.482 538 6298 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 0.958 0.906 – 1.01 0.141 1288 15876 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.879 0.727 – 1.06 0.179 113 1396 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 0.954 0.892 – 1.02 0.164 924 10591 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.1 0.853 – 1.42 0.462 59 714 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.08 0.994 – 1.17 0.0709 623 7207 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.11 0.973 – 1.28 0.117 234 2836 exclusion phecode
201 Hodgkin's disease Neoplasms 0.857 0.732 – 1 0.0543 148 1948 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.01 0.959 – 1.07 0.666 1427 16626 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1 0.944 – 1.06 0.937 1139 13274 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.13 0.982 – 1.29 0.089 227 2671 exclusion phecode
202.24 Large cell lymphoma Neoplasms 0.943 0.849 – 1.05 0.27 367 4259 exclusion phecode
204 Leukemia Neoplasms 1 0.942 – 1.07 0.948 1089 12178 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1.05 0.947 – 1.16 0.359 399 4282 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.864 0.625 – 1.19 0.374 37 391 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.07 0.957 – 1.19 0.238 354 3772 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.03 0.906 – 1.16 0.694 272 3407 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.978 0.848 – 1.13 0.763 199 2434 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.29 1.03 – 1.62 0.0244 84 1062 exclusion phecode
204.4 Multiple myeloma Neoplasms 0.973 0.874 – 1.08 0.609 366 4012 exclusion phecode
208 Benign neoplasm of colon Neoplasms 0.979 0.962 – 0.997 0.0213 13544 140771 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.04 0.957 – 1.12 0.376 672 7170 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.996 0.963 – 1.03 0.84 3520 38169 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.01 0.886 – 1.16 0.847 236 2550 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.994 0.87 – 1.14 0.933 229 2324 exclusion phecode
214 Lipoma Neoplasms 0.981 0.952 – 1.01 0.223 4528 46099 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.974 0.94 – 1.01 0.15 3288 33933 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.06 0.987 – 1.14 0.11 820 8041 exclusion phecode
216 Benign neoplasm of skin Neoplasms 1.02 0.988 – 1.04 0.268 5596 56406 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1 0.91 – 1.1 0.98 464 4614 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.995 0.902 – 1.1 0.925 435 4343 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.974 0.951 – 0.998 0.037 7007 72713 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.98 0.956 – 1 0.0961 7158 74104 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.939 0.82 – 1.08 0.369 224 2565 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.972 0.91 – 1.04 0.386 979 10401 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.09 0.921 – 1.28 0.325 158 1621 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.896 0.741 – 1.08 0.253 121 1213 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.954 0.797 – 1.14 0.612 117 1266 exclusion phecode
224 Benign neoplasm of eye Neoplasms 1.04 0.837 – 1.3 0.71 82 951 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.987 0.738 – 1.32 0.928 44 505 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.994 0.91 – 1.08 0.884 551 5939 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1 0.916 – 1.1 0.967 520 5636 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.92 0.667 – 1.27 0.612 42 432 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.07 0.92 – 1.24 0.391 193 1966 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.989 0.907 – 1.08 0.808 566 6229 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.18 0.96 – 1.45 0.115 105 1339 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.961 0.847 – 1.09 0.533 257 2652 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.913 0.793 – 1.05 0.208 208 2268 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1 0.946 – 1.07 0.874 1156 11651 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.01 0.958 – 1.06 0.822 1761 17521 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.875 0.787 – 0.972 0.0128 379 4355 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.961 0.89 – 1.04 0.309 744 8048 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.91 0.815 – 1.02 0.0968 340 3427 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.991 0.896 – 1.1 0.857 432 4893 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.997 0.939 – 1.06 0.92 1194 13490 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.943 0.84 – 1.06 0.317 308 3343 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.4 1.04 – 1.88 0.0245 54 673 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.98 0.785 – 1.22 0.857 90 1009 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 0.972 0.952 – 0.993 0.0103 9133 104823 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.993 0.918 – 1.07 0.857 680 7945 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.801 0.625 – 1.03 0.0809 59 739 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.971 0.95 – 0.993 0.00945 8702 100319 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.937 0.811 – 1.08 0.38 198 2083 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.985 0.833 – 1.16 0.857 145 1600 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.02 0.857 – 1.21 0.851 141 1538 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.03 0.904 – 1.17 0.689 255 2915 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 0.957 0.939 – 0.975 4.62e-06 11729 137841 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.988 0.94 – 1.04 0.649 1648 20491 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.945 0.801 – 1.12 0.505 147 1765 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.749 0.553 – 1.01 0.061 44 569 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.89 0.79 – 1 0.0546 295 3463 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 0.787 0.629 – 0.984 0.0358 82 1189 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.953 0.934 – 0.972 1.98e-06 10397 125888 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.801 0.616 – 1.04 0.0976 53 771 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.929 0.751 – 1.15 0.496 90 1488 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.965 0.886 – 1.05 0.409 580 7352 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 0.873 0.769 – 0.991 0.0357 256 3709 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 0.979 0.885 – 1.08 0.681 413 5033 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.907 0.777 – 1.06 0.214 164 1980 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.03 0.908 – 1.18 0.618 249 3067 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.06 0.856 – 1.32 0.584 93 980 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.922 0.789 – 1.08 0.304 168 2578 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.942 0.877 – 1.01 0.108 814 9829 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 0.964 0.883 – 1.05 0.41 539 6945 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.05 0.964 – 1.14 0.269 588 6205 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.07 0.983 – 1.18 0.113 538 5537 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.936 0.743 – 1.18 0.571 78 1014 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1 0.905 – 1.1 0.992 428 5015 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.04 0.874 – 1.24 0.645 131 1379 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.995 0.787 – 1.26 0.964 70 710 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.991 0.843 – 1.17 0.914 153 1939 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.896 0.667 – 1.2 0.464 47 684 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.909 0.742 – 1.11 0.357 96 1141 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.01 0.916 – 1.12 0.795 391 4662 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.11 0.92 – 1.34 0.277 111 1321 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.04 0.81 – 1.35 0.739 55 741 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.12 0.857 – 1.48 0.399 54 568 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.982 0.86 – 1.12 0.793 226 2662 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.978 0.855 – 1.12 0.744 225 2659 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.954 0.811 – 1.12 0.57 155 1844 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.861 0.719 – 1.03 0.102 129 1606 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 0.907 0.749 – 1.1 0.317 106 1226 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.913 0.749 – 1.11 0.368 100 1168 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.908 0.71 – 1.16 0.442 65 760 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 1.07 0.874 – 1.3 0.524 103 1087 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.889 0.738 – 1.07 0.212 123 1493 exclusion phecode
260.1 Cachexia Endocrine/metabolic 0.799 0.573 – 1.11 0.187 34 384 exclusion phecode
260.6 Anorexia Endocrine/metabolic 0.985 0.901 – 1.08 0.732 533 5971 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 0.962 0.893 – 1.04 0.306 745 8721 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.933 0.85 – 1.02 0.144 476 5497 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.03 0.914 – 1.17 0.611 274 3215 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.07 0.82 – 1.4 0.609 50 564 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.983 0.843 – 1.15 0.827 163 1785 exclusion phecode
269 Proteinuria Endocrine/metabolic 0.942 0.819 – 1.08 0.405 204 2467 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.988 0.854 – 1.14 0.87 183 2189 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.944 0.805 – 1.11 0.483 155 1876 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 0.967 0.807 – 1.16 0.719 121 1382 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 0.909 0.726 – 1.14 0.404 79 808 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.901 0.643 – 1.26 0.544 34 502 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.08 0.893 – 1.3 0.431 116 1195 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.13 0.923 – 1.37 0.244 104 1034 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.929 0.916 – 0.942 8.62e-26 23508 173534 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.929 0.916 – 0.942 5.89e-26 23462 173359 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.926 0.913 – 0.939 1.58e-26 21816 167990 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.906 0.64 – 1.28 0.576 36 446 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.822 0.677 – 0.998 0.0473 100 1181 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.943 0.792 – 1.12 0.513 132 1575 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.938 0.898 – 0.98 0.00431 2159 27806 exclusion phecode
274.1 Gout Endocrine/metabolic 0.948 0.903 – 0.995 0.029 1790 23708 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.746 0.588 – 0.946 0.0154 64 811 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.865 0.782 – 0.957 0.00505 402 4545 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.863 0.777 – 0.958 0.00562 372 4128 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.989 0.935 – 1.05 0.701 1329 15270 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.979 0.889 – 1.08 0.667 444 4751 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 0.907 0.793 – 1.04 0.158 221 2690 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.01 0.934 – 1.09 0.855 729 8739 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.04 0.862 – 1.26 0.664 110 1266 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 0.927 0.899 – 0.956 1.49e-06 4312 53146 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 0.924 0.887 – 0.963 0.000159 2432 29799 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.996 0.847 – 1.17 0.961 157 1773 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 0.913 0.86 – 0.97 0.003 1136 13274 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 0.882 0.808 – 0.963 0.0051 511 7077 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 0.925 0.862 – 0.993 0.0308 829 10361 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.951 0.877 – 1.03 0.231 610 8391 exclusion phecode
276.41 Acidosis Endocrine/metabolic 0.959 0.88 – 1.05 0.341 551 7628 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 0.915 0.717 – 1.17 0.476 64 805 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 0.927 0.883 – 0.974 0.00252 1706 20643 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 0.848 0.749 – 0.96 0.00911 249 3278 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.12 0.892 – 1.4 0.336 79 925 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 0.957 0.878 – 1.04 0.315 564 6588 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.1 0.975 – 1.24 0.121 292 2726 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.03 0.872 – 1.2 0.763 156 1676 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.983 0.695 – 1.39 0.924 33 396 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.915 0.89 – 0.942 8.34e-10 5079 79942 exclusion phecode
278.1 Obesity Endocrine/metabolic 0.915 0.889 – 0.941 8.22e-10 4985 78739 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 0.925 0.709 – 1.21 0.564 53 641 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.03 0.739 – 1.44 0.852 35 481 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.15 0.97 – 1.36 0.107 147 1864 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.18 0.984 – 1.42 0.0734 128 1567 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.13 0.9 – 1.41 0.298 84 1023 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.02 0.875 – 1.2 0.774 180 1807 exclusion phecode
280 Iron deficiency anemias Hematopoietic 0.962 0.934 – 0.99 0.00891 4852 55931 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.961 0.933 – 0.99 0.00936 4653 53750 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.935 0.831 – 1.05 0.259 300 3300 exclusion phecode
281 Other deficiency anemia Hematopoietic 0.996 0.921 – 1.08 0.923 660 8173 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1 0.923 – 1.08 0.997 643 7842 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.02 0.925 – 1.12 0.733 461 5506 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.946 0.782 – 1.14 0.567 108 1305 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 0.972 0.795 – 1.19 0.778 101 1365 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.07 0.738 – 1.56 0.712 25 395 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.21 0.984 – 1.49 0.0706 96 1087 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.52 1.05 – 2.2 0.0275 32 411 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.04 0.788 – 1.37 0.795 57 615 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.22 0.989 – 1.51 0.0634 89 1016 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.29 1 – 1.66 0.0489 65 791 exclusion phecode
284 Aplastic anemia Hematopoietic 0.929 0.82 – 1.05 0.249 260 3177 exclusion phecode
285 Other anemias Hematopoietic 0.971 0.948 – 0.994 0.0134 7533 88639 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.05 0.9 – 1.22 0.552 184 2001 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 0.895 0.806 – 0.992 0.0351 382 5104 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.928 0.814 – 1.06 0.262 243 3024 exclusion phecode
286 Coagulation defects Hematopoietic 0.973 0.892 – 1.06 0.539 556 6785 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.993 0.883 – 1.12 0.905 303 3323 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 1.03 0.805 – 1.31 0.838 69 699 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1 0.866 – 1.16 0.968 188 2111 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 0.786 0.574 – 1.08 0.134 41 452 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.797 0.578 – 1.1 0.168 38 639 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.05 0.911 – 1.21 0.511 218 2863 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.966 0.908 – 1.03 0.273 1062 12123 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.03 0.837 – 1.27 0.767 91 952 exclusion phecode
287.2 Allergic purpura Hematopoietic 0.915 0.647 – 1.29 0.615 31 380 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 0.957 0.898 – 1.02 0.18 999 11411 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.01 0.891 – 1.14 0.908 269 3089 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.856 0.638 – 1.15 0.302 43 532 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1 0.959 – 1.04 0.994 2419 27445 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.01 0.966 – 1.06 0.644 2033 23035 exclusion phecode
288.11 Neutropenia Hematopoietic 1.01 0.966 – 1.06 0.649 2038 23094 exclusion phecode
288.3 Eosinophilia Hematopoietic 0.869 0.638 – 1.18 0.372 43 525 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.928 0.852 – 1.01 0.0885 547 6333 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.882 0.761 – 1.02 0.0958 183 2120 exclusion phecode
289.4 Lymphadenitis Hematopoietic 0.988 0.939 – 1.04 0.629 1642 19152 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1.02 0.903 – 1.14 0.786 294 3784 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.03 0.881 – 1.21 0.678 158 2158 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 0.983 0.762 – 1.27 0.894 60 656 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.807 0.762 – 0.854 1.84e-13 1237 14121 exclusion phecode
290.1 Dementias Mental Disorders 0.724 0.671 – 0.781 6.02e-17 701 7317 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.726 0.647 – 0.814 4.86e-08 304 3145 exclusion phecode
290.16 Vascular dementia Mental Disorders 0.631 0.529 – 0.754 3.59e-07 138 1448 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.905 0.816 – 1 0.0552 382 4747 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.802 0.609 – 1.06 0.116 42 532 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.942 0.862 – 1.03 0.191 523 6209 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.994 0.804 – 1.23 0.955 91 994 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.987 0.853 – 1.14 0.856 187 2100 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 0.918 0.812 – 1.04 0.178 260 3263 exclusion phecode
292 Neurological disorders Mental Disorders 0.915 0.881 – 0.949 2.58e-06 2973 34009 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.936 0.877 – 0.999 0.0481 964 11145 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.92 0.768 – 1.1 0.365 124 1398 exclusion phecode
292.3 Memory loss Mental Disorders 0.896 0.819 – 0.981 0.0173 495 5147 exclusion phecode
292.4 Altered mental status Mental Disorders 0.939 0.889 – 0.992 0.0256 1362 15955 exclusion phecode
292.6 Hallucinations Mental Disorders 0.8 0.693 – 0.925 0.0025 185 2204 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 0.991 0.939 – 1.05 0.742 1438 15611 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.998 0.918 – 1.09 0.969 596 6610 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.982 0.896 – 1.08 0.691 492 6316 exclusion phecode
295.1 Schizophrenia Mental Disorders 0.956 0.855 – 1.07 0.429 329 4361 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.02 0.837 – 1.24 0.849 104 1343 exclusion phecode
295.3 Psychosis Mental Disorders 0.964 0.792 – 1.17 0.711 106 1237 exclusion phecode
296 Mood disorders Mental Disorders 0.961 0.939 – 0.984 0.000996 7514 92176 exclusion phecode
296.1 Bipolar Mental Disorders 0.963 0.889 – 1.04 0.356 649 7900 exclusion phecode
296.2 Depression Mental Disorders 0.959 0.936 – 0.982 0.000653 7116 87451 exclusion phecode
296.22 Major depressive disorder Mental Disorders 0.963 0.837 – 1.11 0.599 215 2682 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.977 0.841 – 1.13 0.757 177 2295 exclusion phecode
300 Anxiety disorders Mental Disorders 0.979 0.949 – 1.01 0.168 4422 50799 exclusion phecode
300.1 Anxiety disorder Mental Disorders 0.976 0.946 – 1.01 0.134 4082 46880 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 0.973 0.788 – 1.2 0.801 91 1117 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.937 0.853 – 1.03 0.172 447 5221 exclusion phecode
300.13 Phobia Mental Disorders 0.894 0.797 – 1 0.0584 291 3685 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.12 0.908 – 1.39 0.286 103 1083 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 0.931 0.646 – 1.34 0.703 30 407 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.07 0.855 – 1.34 0.556 84 942 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.05 0.827 – 1.34 0.676 73 876 exclusion phecode
301 Personality disorders Mental Disorders 0.905 0.779 – 1.05 0.188 184 2526 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.943 0.728 – 1.22 0.654 61 884 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 1.02 0.88 – 1.18 0.792 193 2131 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.991 0.884 – 1.11 0.881 316 3467 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 1.04 0.908 – 1.18 0.597 243 2580 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.93 0.742 – 1.17 0.531 78 909 exclusion phecode
304 Adjustment reaction Mental Disorders 0.914 0.787 – 1.06 0.238 187 2217 exclusion phecode
305.2 Eating disorder Mental Disorders 0.981 0.76 – 1.27 0.882 67 660 exclusion phecode
306 Other mental disorder Mental Disorders 0.964 0.949 – 0.979 2.65e-06 17931 171014 exclusion phecode
306.9 Tension headache Mental Disorders 0.936 0.815 – 1.07 0.345 215 2332 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.962 0.726 – 1.27 0.787 51 557 exclusion phecode
313.3 Autism Mental Disorders 0.936 0.666 – 1.31 0.701 36 387 exclusion phecode
315 Develomental delays and disorders Mental Disorders 0.892 0.777 – 1.02 0.103 222 2618 exclusion phecode
315.1 Learning disorder Mental Disorders 1.07 0.848 – 1.34 0.583 79 1220 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.865 0.664 – 1.13 0.283 61 632 exclusion phecode
316 Substance addiction and disorders Mental Disorders 0.973 0.939 – 1.01 0.136 3295 40230 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.04 0.745 – 1.46 0.812 36 446 exclusion phecode
317 Alcohol-related disorders Mental Disorders 0.978 0.956 – 0.999 0.0448 8484 95421 exclusion phecode
317.1 Alcoholism Mental Disorders 0.977 0.951 – 1 0.0795 6031 66651 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 0.976 0.889 – 1.07 0.607 464 6308 exclusion phecode
318 Tobacco use disorder Mental Disorders 0.961 0.943 – 0.979 4.03e-05 11370 138699 exclusion phecode
320 Meningitis Neurological 1.04 0.923 – 1.17 0.538 304 3303 exclusion phecode
323 Encephalitis Neurological 0.857 0.753 – 0.976 0.0203 237 2534 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 0.785 0.59 – 1.04 0.0966 48 565 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 0.999 0.865 – 1.15 0.994 195 2159 exclusion phecode
327 Sleep disorders Neurological 1.01 0.942 – 1.09 0.698 751 8710 exclusion phecode
327.3 Sleep apnea Neurological 0.953 0.916 – 0.992 0.0179 2599 33241 exclusion phecode
327.4 Insomnia Neurological 0.933 0.764 – 1.14 0.495 104 1212 exclusion phecode
327.41 Organic or persistent insomnia Neurological 0.921 0.738 – 1.15 0.463 86 1008 exclusion phecode
331 Other cerebral degenerations Neurological 0.911 0.846 – 0.982 0.0145 746 8444 exclusion phecode
331.1 Hydrocephalus Neurological 0.903 0.806 – 1.01 0.0785 319 3687 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 0.927 0.822 – 1.05 0.22 283 3208 exclusion phecode
332 Parkinson's disease Neurological 0.916 0.853 – 0.983 0.0152 839 8195 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.963 0.885 – 1.05 0.387 564 6477 exclusion phecode
333.1 Essential tremor Neurological 0.967 0.806 – 1.16 0.715 123 1544 exclusion phecode
333.2 Myoclonus Neurological 0.913 0.717 – 1.16 0.463 67 700 exclusion phecode
333.4 Torsion dystonia Neurological 1.06 0.911 – 1.24 0.434 171 1861 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.01 0.951 – 1.07 0.755 1176 13481 exclusion phecode
334.1 Spinocerebellar disease Neurological 0.84 0.667 – 1.06 0.137 78 885 exclusion phecode
334.2 Anterior horn cell disease Neurological 1 0.857 – 1.17 0.973 167 1813 exclusion phecode
335 Multiple sclerosis Neurological 1.03 0.96 – 1.1 0.425 868 9840 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 0.993 0.85 – 1.16 0.927 176 1971 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 0.949 0.707 – 1.28 0.729 46 531 exclusion phecode
338 Pain Neurological 1.03 0.935 – 1.13 0.547 447 5647 exclusion phecode
338.1 Acute pain Neurological 1.03 0.896 – 1.17 0.715 233 2867 exclusion phecode
338.2 Chronic pain Neurological 1.05 0.916 – 1.21 0.47 216 2825 exclusion phecode
339 Other headache syndromes Neurological 0.958 0.931 – 0.986 0.00329 5136 57415 exclusion phecode
340 Migraine Neurological 0.986 0.941 – 1.03 0.545 1959 20935 exclusion phecode
340.1 Migrain with aura Neurological 0.954 0.801 – 1.14 0.594 145 1564 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.922 0.784 – 1.08 0.327 159 1884 exclusion phecode
342 Hemiplegia Neurological 0.925 0.865 – 0.989 0.0231 922 11049 exclusion phecode
343 Infantile cerebral palsy Neurological 1.15 0.933 – 1.43 0.189 90 1075 exclusion phecode
344 Other paralytic syndromes Neurological 0.973 0.879 – 1.08 0.598 401 4901 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.977 0.942 – 1.01 0.208 3176 37258 exclusion phecode
345.1 Epilepsy Neurological 0.882 0.81 – 0.961 0.00423 548 6383 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 0.84 0.745 – 0.947 0.00435 286 3261 exclusion phecode
345.12 Partial epilepsy Neurological 0.931 0.799 – 1.08 0.355 165 2051 exclusion phecode
345.3 Convulsions Neurological 0.982 0.931 – 1.04 0.511 1443 16600 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.844 0.684 – 1.04 0.114 86 1072 exclusion phecode
348 Other conditions of brain Neurological 0.905 0.825 – 0.993 0.0344 485 5823 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 0.969 0.828 – 1.13 0.7 166 1967 exclusion phecode
348.4 Cerebral cysts Neurological 0.803 0.649 – 0.993 0.043 93 1012 exclusion phecode
348.7 Coma Neurological 0.999 0.88 – 1.13 0.982 257 2661 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 0.923 0.779 – 1.09 0.352 148 1886 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.05 0.928 – 1.2 0.422 261 2897 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.988 0.859 – 1.14 0.863 217 2552 exclusion phecode
350 Abnormal movement Neurological 0.94 0.894 – 0.988 0.0147 1674 19489 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.04 0.951 – 1.13 0.41 572 6483 exclusion phecode
350.2 Abnormality of gait Neurological 0.913 0.856 – 0.975 0.00649 964 11619 exclusion phecode
350.3 Lack of coordination Neurological 0.882 0.772 – 1.01 0.0637 232 2688 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.1 0.775 – 1.57 0.587 35 392 exclusion phecode
351 Other peripheral nerve disorders Neurological 0.967 0.945 – 0.989 0.00352 8100 90807 exclusion phecode
352 Disorders of other cranial nerves Neurological 0.947 0.885 – 1.01 0.114 896 10014 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.924 0.824 – 1.04 0.174 301 3370 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 0.955 0.876 – 1.04 0.295 564 6473 exclusion phecode
353 Nerve root and plexus disorders Neurological 0.986 0.913 – 1.07 0.73 689 8258 exclusion phecode
353.1 Nerve plexus lesions Neurological 1.05 0.822 – 1.34 0.705 71 851 exclusion phecode
353.2 Nerve root lesions Neurological 1.48 1.02 – 2.16 0.0412 31 422 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.703 0.579 – 0.852 0.000333 102 1122 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 0.949 0.883 – 1.02 0.15 805 10024 exclusion phecode
358 Myoneural disorders Neurological 0.775 0.653 – 0.921 0.0037 132 1528 exclusion phecode
358.1 Myasthenia gravis Neurological 0.761 0.635 – 0.912 0.00312 120 1406 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.944 0.839 – 1.06 0.337 293 3443 exclusion phecode
359.1 Muscular dystrophies Neurological 0.932 0.749 – 1.16 0.523 80 917 exclusion phecode
359.2 Myopathy Neurological 0.944 0.825 – 1.08 0.404 225 2635 exclusion phecode
360 Disorders of the globe Sense Organs 0.92 0.805 – 1.05 0.222 245 2473 exclusion phecode
360.2 Progressive myopia Sense Organs 0.925 0.792 – 1.08 0.326 185 1834 exclusion phecode
361 Retinal detachments and defects Sense Organs 1.03 0.99 – 1.08 0.14 2455 23935 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.04 0.972 – 1.11 0.273 1056 10273 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 1.12 0.841 – 1.48 0.446 47 513 exclusion phecode
362 Other retinal disorders Sense Organs 0.971 0.933 – 1.01 0.156 2582 27804 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.936 0.887 – 0.987 0.0147 1468 15664 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.936 0.887 – 0.987 0.0147 1465 15638 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.03 0.858 – 1.24 0.728 113 1178 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1.09 0.868 – 1.38 0.447 74 720 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1 0.918 – 1.1 0.943 546 6208 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 1.06 0.883 – 1.26 0.552 128 1366 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.921 0.704 – 1.21 0.551 53 596 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.1 0.878 – 1.37 0.41 82 816 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.956 0.792 – 1.15 0.639 118 1255 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.949 0.718 – 1.26 0.716 50 497 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.955 0.867 – 1.05 0.351 443 4679 exclusion phecode
364.1 Corneal opacity Sense Organs 0.95 0.724 – 1.25 0.709 53 673 exclusion phecode
364.2 Corneal edema Sense Organs 0.719 0.536 – 0.963 0.027 46 583 exclusion phecode
364.4 Corneal degenerations Sense Organs 1.07 0.905 – 1.26 0.444 146 1469 exclusion phecode
364.41 Keratoconus Sense Organs 1.27 0.975 – 1.65 0.0769 66 671 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.889 0.751 – 1.05 0.171 142 1530 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.98 0.765 – 1.26 0.872 68 725 exclusion phecode
365 Glaucoma Sense Organs 0.988 0.952 – 1.02 0.509 3110 31937 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 0.954 0.886 – 1.03 0.217 758 7513 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.963 0.893 – 1.04 0.317 755 7475 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.925 0.845 – 1.01 0.0951 502 5055 exclusion phecode
366 Cataract Sense Organs 0.993 0.975 – 1.01 0.432 13499 122097 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.963 0.708 – 1.31 0.81 44 511 exclusion phecode
366.2 Senile cataract Sense Organs 0.992 0.965 – 1.02 0.555 5535 58839 exclusion phecode
366.3 Traumatic cataract Sense Organs 0.911 0.718 – 1.15 0.439 75 779 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.983 0.935 – 1.03 0.505 1663 17545 exclusion phecode
367.1 Myopia Sense Organs 1.01 0.941 – 1.08 0.834 923 9049 exclusion phecode
367.2 Astigmatism Sense Organs 0.965 0.806 – 1.15 0.693 131 1363 exclusion phecode
367.8 Hypermetropia Sense Organs 1.05 0.891 – 1.23 0.58 167 1818 exclusion phecode
367.9 Blindness and low vision Sense Organs 0.936 0.851 – 1.03 0.179 448 5268 exclusion phecode
368 Visual disturbances Sense Organs 1.02 0.971 – 1.07 0.467 1945 21657 exclusion phecode
368.1 Amblyopia Sense Organs 1.09 0.976 – 1.22 0.127 349 3852 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.07 0.969 – 1.17 0.191 479 5371 exclusion phecode
368.3 Anisometropia Sense Organs 0.973 0.8 – 1.18 0.783 120 1146 exclusion phecode
368.4 Visual field defects Sense Organs 0.942 0.819 – 1.08 0.401 215 2494 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.908 0.818 – 1.01 0.0711 383 4442 exclusion phecode
369 Infection of the eye Sense Organs 0.97 0.871 – 1.08 0.579 353 4047 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.978 0.781 – 1.23 0.85 84 901 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 1.01 0.843 – 1.21 0.918 131 1557 exclusion phecode
370 Keratitis Sense Organs 0.929 0.803 – 1.08 0.324 181 2070 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.853 0.697 – 1.04 0.123 88 1007 exclusion phecode
371 Inflammation of the eye Sense Organs 0.996 0.953 – 1.04 0.859 2209 22275 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.01 0.898 – 1.13 0.89 309 3508 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 1.01 0.957 – 1.06 0.839 1752 17203 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.01 0.924 – 1.1 0.871 557 5498 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.992 0.96 – 1.03 0.653 3884 41132 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.976 0.906 – 1.05 0.531 723 7728 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.955 0.901 – 1.01 0.118 1248 13068 exclusion phecode
375 Disorders of lacrimal system Sense Organs 1 0.951 – 1.06 0.942 1541 15792 exclusion phecode
375.2 Epiphora Sense Organs 1.03 0.95 – 1.12 0.459 633 6386 exclusion phecode
376 Disorders of the orbit Sense Organs 0.794 0.6 – 1.05 0.106 55 624 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1 0.876 – 1.14 0.99 241 2614 exclusion phecode
377.1 Optic atrophy Sense Organs 0.944 0.672 – 1.33 0.739 34 421 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.853 0.687 – 1.06 0.151 83 938 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.01 0.948 – 1.08 0.717 990 10424 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.07 0.984 – 1.16 0.116 653 6694 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.897 0.757 – 1.06 0.211 137 1602 exclusion phecode
378.5 Paralytic strabismus Sense Organs 0.946 0.817 – 1.1 0.461 189 2016 exclusion phecode
379 Other disorders of eye Sense Organs 0.981 0.942 – 1.02 0.367 2511 26813 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.98 0.917 – 1.05 0.547 951 10020 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.99 0.933 – 1.05 0.731 1202 13021 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.07 0.796 – 1.44 0.646 52 510 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.999 0.882 – 1.13 0.989 272 2976 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.989 0.805 – 1.22 0.918 99 1234 exclusion phecode
380 Disorders of external ear Sense Organs 0.899 0.816 – 0.991 0.0318 430 4704 exclusion phecode
380.1 Otitis externa Sense Organs 0.998 0.893 – 1.12 0.974 325 3806 exclusion phecode
380.4 Impacted cerumen Sense Organs 1.01 0.884 – 1.15 0.903 246 2638 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.983 0.931 – 1.04 0.541 1403 15801 exclusion phecode
381.1 Otitis media Sense Organs 0.963 0.907 – 1.02 0.217 1156 12927 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.935 0.858 – 1.02 0.13 543 6288 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 1.05 0.882 – 1.24 0.593 137 1401 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.89 0.73 – 1.08 0.247 105 1279 exclusion phecode
381.9 Otorrhea Sense Organs 1.07 0.911 – 1.25 0.425 173 2081 exclusion phecode
382 Otalgia Sense Organs 0.888 0.77 – 1.02 0.103 201 2262 exclusion phecode
383 Otosclerosis Sense Organs 1.05 0.912 – 1.21 0.501 227 2251 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1 0.938 – 1.08 0.9 871 9591 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.01 0.931 – 1.09 0.881 698 7687 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.954 0.874 – 1.04 0.301 537 5841 exclusion phecode
385.3 Cholesteatoma Sense Organs 0.919 0.831 – 1.02 0.101 414 4512 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.95 0.814 – 1.11 0.519 170 1804 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.976 0.919 – 1.04 0.426 1170 12737 exclusion phecode
386.1 Meniere's disease Sense Organs 1 0.902 – 1.11 0.968 373 4234 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.921 0.809 – 1.05 0.208 252 2728 exclusion phecode
386.3 Labyrinthitis Sense Organs 0.99 0.905 – 1.08 0.821 529 5631 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.959 0.924 – 0.995 0.0252 3084 33474 exclusion phecode
388 Other disorders of ear Sense Organs 1.03 0.871 – 1.22 0.712 140 1499 exclusion phecode
389 Hearing loss Sense Organs 0.993 0.955 – 1.03 0.728 2804 30660 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.925 0.825 – 1.04 0.185 322 3318 exclusion phecode
389.2 Conductive hearing loss Sense Organs 0.912 0.813 – 1.02 0.12 301 3321 exclusion phecode
389.4 Tinnitus Sense Organs 1 0.9 – 1.12 0.97 354 3794 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 0.969 0.934 – 1 0.0825 3219 35794 exclusion phecode
394.2 Mitral valve disease Circulatory System 0.975 0.931 – 1.02 0.272 2023 21829 exclusion phecode
394.3 Aortic valve disease Circulatory System 0.944 0.878 – 1.01 0.118 804 9331 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 0.966 0.892 – 1.05 0.395 653 7675 exclusion phecode
395 Heart valve disorders Circulatory System 0.951 0.915 – 0.989 0.0112 2789 30867 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.98 0.935 – 1.03 0.382 1950 21111 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.03 0.88 – 1.21 0.702 166 2032 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 0.968 0.764 – 1.23 0.787 66 761 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.851 0.652 – 1.11 0.236 57 694 exclusion phecode
395.6 Heart valve replaced Circulatory System 0.896 0.84 – 0.957 0.000988 962 10882 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.04 0.965 – 1.13 0.293 700 7576 exclusion phecode
401 Hypertension Circulatory System 0.957 0.947 – 0.967 1.39e-16 47355 202882 exclusion phecode
401.1 Essential hypertension Circulatory System 0.958 0.948 – 0.968 3.75e-16 47209 202716 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 0.893 0.837 – 0.951 0.000464 996 14380 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 0.877 0.766 – 1 0.0557 216 2808 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.892 0.83 – 0.959 0.00187 786 11660 exclusion phecode
401.3 Other hypertensive complications Circulatory System 0.861 0.68 – 1.09 0.217 72 1099 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 0.957 0.896 – 1.02 0.187 944 11131 exclusion phecode
411 Ischemic Heart Disease Circulatory System 0.948 0.935 – 0.962 1.15e-12 20921 155699 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.942 0.91 – 0.976 0.000842 3364 37996 exclusion phecode
411.2 Myocardial infarction Circulatory System 0.946 0.925 – 0.968 1.97e-06 8040 83795 exclusion phecode
411.3 Angina pectoris Circulatory System 0.957 0.938 – 0.976 1.71e-05 10470 105852 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 0.933 0.917 – 0.95 1.36e-14 13861 114960 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.949 0.869 – 1.04 0.247 528 5213 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.953 0.934 – 0.973 4.96e-06 9951 97427 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.01 0.942 – 1.09 0.725 788 9090 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 0.954 0.899 – 1.01 0.118 1157 13578 exclusion phecode
414.2 ASCVD Circulatory System 0.788 0.592 – 1.05 0.102 43 552 exclusion phecode
415 Pulmonary heart disease Circulatory System 0.971 0.934 – 1.01 0.145 2674 32854 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.843 0.621 – 1.15 0.275 45 518 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.899 0.802 – 1.01 0.068 313 4358 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 0.874 0.768 – 0.995 0.0418 244 3268 exclusion phecode
416 Cardiomegaly Circulatory System 0.95 0.903 – 1 0.0482 1604 19719 exclusion phecode
418 Nonspecific chest pain Circulatory System 0.964 0.95 – 0.978 1.19e-06 19037 199790 exclusion phecode
418.1 Precordial pain Circulatory System 0.975 0.935 – 1.02 0.235 2339 26304 exclusion phecode
420 Carditis Circulatory System 0.997 0.943 – 1.05 0.904 1370 15396 exclusion phecode
420.1 Myocarditis Circulatory System 0.821 0.658 – 1.02 0.0789 84 949 exclusion phecode
420.2 Pericarditis Circulatory System 1.04 0.966 – 1.11 0.32 867 9808 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.02 0.858 – 1.2 0.851 152 1639 exclusion phecode
420.22 Chronic pericarditis Circulatory System 0.98 0.774 – 1.24 0.867 70 811 exclusion phecode
420.3 Endocarditis Circulatory System 0.971 0.885 – 1.07 0.532 472 5242 exclusion phecode
425 Cardiomyopathy Circulatory System 1.01 0.941 – 1.09 0.754 830 9471 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.01 0.938 – 1.09 0.812 810 9210 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.955 0.782 – 1.17 0.654 91 992 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1 0.829 – 1.21 0.986 115 1236 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.02 0.713 – 1.45 0.931 32 440 exclusion phecode
426 Cardiac conduction disorders Circulatory System 0.96 0.931 – 0.989 0.00803 4581 50845 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 0.969 0.917 – 1.02 0.26 1385 15565 exclusion phecode
426.21 First degree AV block Circulatory System 0.93 0.858 – 1.01 0.0777 639 7308 exclusion phecode
426.23 Second degree AV block Circulatory System 1.03 0.916 – 1.16 0.616 309 3296 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 0.951 0.856 – 1.06 0.354 374 4272 exclusion phecode
426.25 Other heart block Circulatory System 0.883 0.714 – 1.09 0.253 88 998 exclusion phecode
426.3 Bundle branch block Circulatory System 0.995 0.952 – 1.04 0.823 2195 24480 exclusion phecode
426.31 Right bundle branch block Circulatory System 0.983 0.92 – 1.05 0.613 973 11015 exclusion phecode
426.32 Left bundle branch block Circulatory System 0.991 0.933 – 1.05 0.78 1153 12780 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.971 0.833 – 1.13 0.712 165 1749 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 0.991 0.707 – 1.39 0.958 35 429 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.91 0.864 – 0.957 0.000265 1612 18235 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.907 0.86 – 0.957 0.000355 1474 16763 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 0.965 0.949 – 0.98 1.35e-05 16156 151861 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 0.977 0.936 – 1.02 0.308 2153 23545 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.01 0.956 – 1.06 0.824 1583 17190 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.878 0.81 – 0.951 0.0015 629 6941 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 0.956 0.936 – 0.976 2.87e-05 9600 98374 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.955 0.915 – 0.997 0.0346 2283 23887 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.972 0.903 – 1.05 0.46 743 8880 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.97 0.85 – 1.11 0.645 237 2581 exclusion phecode
427.42 Cardiac arrest Circulatory System 0.974 0.897 – 1.06 0.537 598 7385 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.945 0.872 – 1.02 0.161 650 6966 exclusion phecode
427.6 Premature beats Circulatory System 1 0.9 – 1.11 0.998 382 3940 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1.08 0.872 – 1.34 0.476 88 855 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1 0.948 – 1.06 0.911 1316 16148 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.995 0.881 – 1.12 0.942 286 2967 exclusion phecode
427.9 Palpitations Circulatory System 0.963 0.925 – 1 0.0621 2666 27964 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.924 0.892 – 0.957 1.16e-05 3291 41121 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 0.912 0.858 – 0.969 0.00304 1083 15387 exclusion phecode
428.2 Heart failure NOS Circulatory System 0.922 0.887 – 0.959 4.81e-05 2683 32705 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 0.966 0.881 – 1.06 0.455 492 5220 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.06 0.791 – 1.43 0.682 41 488 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.961 0.862 – 1.07 0.467 353 3784 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 0.985 0.83 – 1.17 0.859 139 1442 exclusion phecode
430 Intracranial hemorrhage Circulatory System 0.98 0.925 – 1.04 0.489 1254 13918 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.04 0.954 – 1.14 0.347 529 6119 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 0.942 0.862 – 1.03 0.191 519 5607 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 0.875 0.756 – 1.01 0.0751 185 1950 exclusion phecode
433 Cerebrovascular disease Circulatory System 0.934 0.909 – 0.96 9.83e-07 5615 63986 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.886 0.821 – 0.955 0.00169 696 8671 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 0.845 0.716 – 0.998 0.0477 137 1672 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.899 0.864 – 0.935 1.23e-07 2667 31006 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.881 0.827 – 0.938 8.37e-05 1034 12345 exclusion phecode
433.3 Cerebral ischemia Circulatory System 0.974 0.93 – 1.02 0.266 1904 21111 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1 0.948 – 1.06 0.98 1431 15612 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 0.977 0.862 – 1.11 0.71 256 2902 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.962 0.892 – 1.04 0.31 749 9409 exclusion phecode
440 Atherosclerosis Circulatory System 0.909 0.845 – 0.979 0.0114 742 10155 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.06 0.818 – 1.37 0.67 57 843 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.88 0.798 – 0.971 0.0105 425 5998 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 0.982 0.84 – 1.15 0.824 153 2083 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.01 0.906 – 1.12 0.912 374 4407 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.05 0.905 – 1.23 0.494 182 2042 exclusion phecode
442 Other aneurysm Circulatory System 0.971 0.915 – 1.03 0.342 1154 14015 exclusion phecode
442.1 Aortic aneurysm Circulatory System 0.944 0.881 – 1.01 0.0996 866 10793 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.953 0.871 – 1.04 0.295 507 6886 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.1 0.851 – 1.43 0.462 61 749 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.08 0.881 – 1.32 0.458 105 1256 exclusion phecode
442.4 Arterial dissection Circulatory System 1.1 0.81 – 1.5 0.533 41 405 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 0.966 0.811 – 1.15 0.701 128 1496 exclusion phecode
443 Peripheral vascular disease Circulatory System 0.95 0.911 – 0.992 0.0199 2246 28619 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 0.966 0.898 – 1.04 0.354 764 8336 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.889 0.769 – 1.03 0.111 194 2890 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 0.955 0.914 – 0.998 0.0398 2121 26852 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.95 0.899 – 1 0.0656 1375 18803 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 0.913 0.835 – 1 0.0491 494 6891 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.87 0.775 – 0.977 0.0186 293 4136 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.974 0.885 – 1.07 0.588 447 5981 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.972 0.798 – 1.18 0.778 101 1388 exclusion phecode
446.5 Giant cell arteritis Circulatory System 0.956 0.83 – 1.1 0.535 206 2788 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.01 0.851 – 1.21 0.887 133 1748 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 0.958 0.89 – 1.03 0.266 740 9831 exclusion phecode
447.1 Stricture of artery Circulatory System 0.965 0.88 – 1.06 0.443 478 6433 exclusion phecode
448 Disease of capillaries Circulatory System 1 0.814 – 1.24 0.972 95 1002 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.01 0.911 – 1.12 0.827 371 5186 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.978 0.938 – 1.02 0.284 2451 29221 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.983 0.941 – 1.03 0.422 2275 27244 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 0.921 0.824 – 1.03 0.146 332 4220 exclusion phecode
454 Varicose veins Circulatory System 0.982 0.959 – 1 0.112 8057 82020 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 0.983 0.961 – 1.01 0.143 8299 84090 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.901 0.813 – 1 0.0498 377 4651 exclusion phecode
455 Hemorrhoids Circulatory System 1 0.987 – 1.02 0.706 16636 173078 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.01 0.834 – 1.23 0.896 102 1372 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.07 0.845 – 1.34 0.591 77 706 exclusion phecode
458 Hypotension Circulatory System 0.942 0.911 – 0.974 0.000423 3749 42268 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 0.912 0.851 – 0.977 0.00875 866 9839 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 0.844 0.714 – 0.997 0.0461 151 1677 exclusion phecode
458.9 Hypotension NOS Circulatory System 0.96 0.92 – 1 0.0671 2224 25653 exclusion phecode
459 Other disorders of circulatory system Circulatory System 0.965 0.945 – 0.985 0.000529 10143 118260 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.08 0.854 – 1.37 0.516 77 1034 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 0.965 0.946 – 0.985 0.000612 10058 117246 exclusion phecode
464 Acute sinusitis Respiratory 0.954 0.799 – 1.14 0.601 125 1443 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.03 0.979 – 1.09 0.235 1452 16681 exclusion phecode
465.2 Acute pharyngitis Respiratory 1.02 0.93 – 1.11 0.723 543 6138 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.955 0.785 – 1.16 0.645 108 1205 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.984 0.949 – 1.02 0.357 3346 35198 exclusion phecode
471 Nasal polyps Respiratory 0.961 0.92 – 1 0.0665 2303 24613 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.926 0.856 – 1 0.0534 668 7104 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1 0.952 – 1.05 0.982 1655 18713 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.03 0.797 – 1.33 0.816 65 772 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.06 0.908 – 1.23 0.48 173 1963 exclusion phecode
473.4 Voice disturbance Respiratory 0.978 0.904 – 1.06 0.574 679 7854 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 0.993 0.937 – 1.05 0.802 1249 13375 exclusion phecode
474.1 Acute tonsillitis Respiratory 0.966 0.87 – 1.07 0.51 377 4107 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.02 0.947 – 1.1 0.612 792 8494 exclusion phecode
475 Chronic sinusitis Respiratory 0.965 0.919 – 1.01 0.163 1696 19122 exclusion phecode
476 Allergic rhinitis Respiratory 1 0.927 – 1.08 0.993 741 7818 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.06 1.01 – 1.11 0.0306 1618 17840 exclusion phecode
478 Throat pain Respiratory 1.02 0.906 – 1.16 0.704 272 2762 exclusion phecode
479 Other upper respiratory disease Respiratory 1 0.965 – 1.04 0.868 2829 30135 exclusion phecode
480 Pneumonia Respiratory 0.964 0.939 – 0.99 0.00674 5917 75903 exclusion phecode
480.1 Bacterial pneumonia Respiratory 0.96 0.929 – 0.993 0.0165 3729 48773 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 0.959 0.926 – 0.994 0.0204 3322 43229 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 0.846 0.61 – 1.17 0.318 34 660 exclusion phecode
480.2 Viral pneumonia Respiratory 0.77 0.59 – 1 0.0541 50 532 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.813 0.621 – 1.06 0.13 49 734 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.962 0.875 – 1.06 0.426 456 5828 exclusion phecode
481 Influenza Respiratory 0.878 0.761 – 1.01 0.0746 197 2429 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.898 0.739 – 1.09 0.28 101 1426 exclusion phecode
495 Asthma Respiratory 0.978 0.962 – 0.994 0.0059 16105 186311 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.05 0.89 – 1.25 0.543 144 1857 exclusion phecode
496 Chronic airway obstruction Respiratory 0.943 0.917 – 0.969 3.19e-05 5312 74370 exclusion phecode
496.1 Emphysema Respiratory 0.911 0.851 – 0.976 0.00823 873 12877 exclusion phecode
496.2 Chronic bronchitis Respiratory 0.923 0.874 – 0.976 0.00487 1312 21613 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 0.905 0.854 – 0.96 0.000828 1185 19854 exclusion phecode
496.3 Bronchiectasis Respiratory 0.931 0.871 – 0.996 0.0369 888 13844 exclusion phecode
497 Bronchitis Respiratory 0.999 0.894 – 1.12 0.992 325 4608 exclusion phecode
500 Lung disease due to external agents Respiratory 0.906 0.79 – 1.04 0.156 212 2987 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.02 0.765 – 1.35 0.917 44 570 exclusion phecode
500.2 Pneumoconiosis Respiratory 0.914 0.761 – 1.1 0.336 117 1761 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.04 0.941 – 1.16 0.409 387 4851 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.979 0.888 – 1.08 0.67 429 6682 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 0.958 0.846 – 1.09 0.5 268 3710 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.979 0.837 – 1.15 0.795 153 2399 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1 0.707 – 1.42 0.986 32 451 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.02 0.949 – 1.11 0.54 712 8398 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 0.982 0.95 – 1.01 0.281 3826 47147 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.998 0.94 – 1.06 0.946 1178 14650 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.951 0.899 – 1 0.0723 1324 19039 exclusion phecode
509.1 Respiratory failure Respiratory 0.937 0.88 – 0.998 0.0427 1033 15114 exclusion phecode
509.2 Respiratory insufficiency Respiratory 0.934 0.873 – 0.999 0.0467 897 13216 exclusion phecode
509.5 Respiratory arrest Respiratory 1.06 0.864 – 1.31 0.555 83 1050 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.902 0.781 – 1.04 0.158 205 2819 exclusion phecode
510 Other diseases of lung Respiratory 0.929 0.845 – 1.02 0.126 450 5445 exclusion phecode
512 Other symptoms of respiratory system Respiratory 0.962 0.936 – 0.989 0.006 5473 66040 exclusion phecode
512.1 Wheezing Respiratory 0.908 0.76 – 1.09 0.291 120 1595 exclusion phecode
512.2 Painful respiration Respiratory 1.09 0.916 – 1.29 0.336 137 1502 exclusion phecode
512.7 Shortness of breath Respiratory 0.944 0.912 – 0.976 0.000902 3513 42724 exclusion phecode
512.8 Cough Respiratory 0.971 0.924 – 1.02 0.24 1722 21000 exclusion phecode
512.9 Other dyspnea Respiratory 1.01 0.931 – 1.11 0.74 540 6598 exclusion phecode
513 Respiratory abnormalities Respiratory 1.02 0.909 – 1.13 0.785 343 4472 exclusion phecode
513.3 Hypoventilation Respiratory 0.815 0.575 – 1.16 0.251 26 591 exclusion phecode
513.4 Hyperventilation Respiratory 1.08 0.916 – 1.26 0.376 163 2008 exclusion phecode
513.8 Disorders of diaphragm Respiratory 0.982 0.794 – 1.22 0.87 94 1166 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 0.91 0.863 – 0.96 0.000539 1429 17876 exclusion phecode
516 Abnormal sputum Respiratory 0.983 0.929 – 1.04 0.562 1242 15671 exclusion phecode
516.1 Hemoptysis Respiratory 0.985 0.93 – 1.04 0.617 1214 15246 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.978 0.952 – 1.01 0.12 5415 68518 exclusion phecode
519.2 Respiratory complications Respiratory 1.04 0.891 – 1.2 0.65 173 2409 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.968 0.941 – 0.997 0.0278 5095 64693 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.16 1 – 1.34 0.0438 211 2257 exclusion phecode
520 Disorders of tooth development Digestive 1 0.952 – 1.06 0.895 1519 15356 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.993 0.719 – 1.37 0.968 36 381 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 1 0.957 – 1.05 0.856 1779 17721 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1 0.958 – 1.05 0.899 1999 22332 exclusion phecode
521.1 Dental caries Digestive 0.997 0.953 – 1.04 0.912 2000 22410 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.05 0.986 – 1.11 0.132 1234 13087 exclusion phecode
522.5 Periapical abscess Digestive 1.07 0.998 – 1.16 0.0556 804 8697 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.02 0.964 – 1.09 0.448 1174 12417 exclusion phecode
523.1 Gingivitis Digestive 1.34 1.04 – 1.73 0.0242 72 800 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 0.98 0.913 – 1.05 0.577 830 8709 exclusion phecode
523.31 Acute periodontitis Digestive 0.936 0.853 – 1.03 0.162 477 4987 exclusion phecode
523.32 Chronic periodontitis Digestive 1.07 0.965 – 1.19 0.195 404 4140 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.886 0.776 – 1.01 0.0718 238 2476 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.874 0.762 – 1 0.0546 218 2283 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.973 0.927 – 1.02 0.266 1773 19540 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.03 0.761 – 1.39 0.858 46 491 exclusion phecode
526 Diseases of the jaws Digestive 1 0.921 – 1.08 0.992 648 6903 exclusion phecode
526.1 Cysts of the jaws Digestive 1.04 0.907 – 1.18 0.601 248 2449 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.951 0.7 – 1.29 0.75 45 459 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.08 0.918 – 1.28 0.342 154 1800 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.1 0.93 – 1.31 0.262 151 1748 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.931 0.733 – 1.18 0.553 74 820 exclusion phecode
526.9 Jaw disease NOS Digestive 0.888 0.754 – 1.05 0.154 152 1681 exclusion phecode
527 Diseases of the salivary glands Digestive 1.07 0.972 – 1.19 0.163 440 5148 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.22 0.921 – 1.62 0.165 55 627 exclusion phecode
527.2 Sialoadenitis Digestive 1.02 0.891 – 1.17 0.757 230 2688 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.1 0.801 – 1.51 0.559 37 476 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 0.986 0.783 – 1.24 0.902 84 887 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.999 0.96 – 1.04 0.959 2655 28369 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.08 0.96 – 1.21 0.198 295 3445 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.16 1.02 – 1.33 0.0211 245 2859 exclusion phecode
528.12 Oral aphthae Digestive 0.763 0.58 – 1 0.0532 53 627 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.832 0.691 – 1 0.052 118 1322 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.995 0.807 – 1.23 0.966 89 897 exclusion phecode
528.41 Cyst of the salivary gland Digestive 1.07 0.836 – 1.36 0.607 67 694 exclusion phecode
528.5 Diseases of lips Digestive 0.942 0.859 – 1.03 0.204 482 4968 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.03 0.891 – 1.19 0.689 198 2225 exclusion phecode
528.7 Sialolithiasis Digestive 1.06 0.926 – 1.22 0.386 222 2331 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1 0.933 – 1.08 0.941 797 8979 exclusion phecode
529.1 Glossitis Digestive 0.964 0.831 – 1.12 0.625 179 2206 exclusion phecode
530 Diseases of esophagus Digestive 0.966 0.953 – 0.98 1.54e-06 22026 207189 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.968 0.954 – 0.982 1.05e-05 20602 201966 exclusion phecode
530.11 GERD Digestive 0.969 0.953 – 0.986 0.000284 14884 166693 exclusion phecode
530.12 Ulcer of esophagus Digestive 0.98 0.946 – 1.01 0.252 3384 38379 exclusion phecode
530.14 Reflux esophagitis Digestive 0.977 0.953 – 1 0.0622 6945 77409 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.958 0.898 – 1.02 0.183 1005 12426 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 0.986 0.931 – 1.04 0.635 1247 13707 exclusion phecode
530.5 Disorders of esophageal motility Digestive 0.93 0.842 – 1.03 0.155 421 4754 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.14 0.926 – 1.41 0.211 105 1122 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.915 0.801 – 1.04 0.187 228 2585 exclusion phecode
530.9 Heartburn Digestive 0.968 0.917 – 1.02 0.232 1458 15249 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.997 0.967 – 1.03 0.847 4524 51894 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.01 0.91 – 1.12 0.862 397 4671 exclusion phecode
531.2 Gastric ulcer Digestive 0.989 0.95 – 1.03 0.601 2588 29729 exclusion phecode
531.3 Duodenal ulcer Digestive 0.989 0.945 – 1.04 0.644 1942 22039 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.08 0.952 – 1.23 0.229 251 3091 exclusion phecode
532 Dysphagia Digestive 0.978 0.948 – 1.01 0.153 4348 47272 exclusion phecode
535 Gastritis and duodenitis Digestive 0.981 0.966 – 0.996 0.011 18615 192783 exclusion phecode
535.1 Acute gastritis Digestive 0.986 0.917 – 1.06 0.697 772 8719 exclusion phecode
535.2 Atrophic gastritis Digestive 0.898 0.79 – 1.02 0.0965 262 2704 exclusion phecode
535.6 Duodenitis Digestive 0.976 0.948 – 1 0.0999 4998 56138 exclusion phecode
535.8 Other specified gastritis Digestive 0.971 0.944 – 0.998 0.0388 5314 59015 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.942 0.748 – 1.19 0.608 78 855 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.997 0.855 – 1.16 0.973 173 1843 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 0.978 0.936 – 1.02 0.307 2148 24930 exclusion phecode
540 Appendiceal conditions Digestive 0.986 0.944 – 1.03 0.51 2234 22960 exclusion phecode
540.1 Appendicitis Digestive 0.993 0.949 – 1.04 0.75 2102 21524 exclusion phecode
540.11 Acute appendicitis Digestive 1.01 0.96 – 1.05 0.789 1909 19342 exclusion phecode
550 Abdominal hernia Digestive 0.985 0.973 – 0.997 0.0114 31341 209901 exclusion phecode
550.1 Inguinal hernia Digestive 1.01 0.99 – 1.03 0.382 12255 93248 exclusion phecode
550.2 Diaphragmatic hernia Digestive 0.971 0.956 – 0.986 0.000195 17340 175917 exclusion phecode
550.3 Femoral hernia Digestive 0.932 0.849 – 1.02 0.141 494 4791 exclusion phecode
550.4 Umbilical hernia Digestive 0.976 0.935 – 1.02 0.256 2307 27857 exclusion phecode
550.5 Ventral hernia Digestive 0.965 0.923 – 1.01 0.121 2093 25255 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 0.954 0.918 – 0.993 0.0195 2703 33185 exclusion phecode
555.1 Regional enteritis Digestive 0.935 0.876 – 0.998 0.0429 966 12934 exclusion phecode
555.2 Ulcerative colitis Digestive 0.959 0.916 – 1 0.072 1995 23783 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 0.98 0.881 – 1.09 0.716 359 4062 exclusion phecode
556 Ulceration of the lower GI tract Digestive 0.898 0.83 – 0.972 0.00807 658 7876 exclusion phecode
556.1 Ulceration of intestine Digestive 0.893 0.807 – 0.989 0.0293 400 4931 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.968 0.837 – 1.12 0.654 198 2218 exclusion phecode
557.1 Celiac disease Digestive 0.985 0.932 – 1.04 0.595 1365 13631 exclusion phecode
558 Noninfectious gastroenteritis Digestive 0.989 0.969 – 1.01 0.272 9948 115131 exclusion phecode
559 Ileostomy status Digestive 0.904 0.848 – 0.964 0.00216 997 12248 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 0.967 0.929 – 1.01 0.108 2586 29012 exclusion phecode
560.1 Paralytic ileus Digestive 1.06 0.948 – 1.19 0.308 332 3907 exclusion phecode
560.2 Impaction of intestine Digestive 0.957 0.82 – 1.12 0.58 172 1921 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.924 0.848 – 1.01 0.0714 578 6091 exclusion phecode
560.4 Other intestinal obstruction Digestive 0.95 0.91 – 0.992 0.0208 2218 24721 exclusion phecode
561 Symptoms involving digestive system Digestive 0.996 0.977 – 1.02 0.71 10921 116465 exclusion phecode
561.1 Diarrhea Digestive 1.01 0.891 – 1.13 0.927 291 3382 exclusion phecode
561.2 Flatulence Digestive 1.02 0.958 – 1.08 0.577 1173 12501 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 0.974 0.959 – 0.989 0.000845 17644 157141 exclusion phecode
562.1 Diverticulosis Digestive 0.974 0.958 – 0.989 0.000755 17623 157097 exclusion phecode
563 Constipation Digestive 0.976 0.953 – 1 0.0572 6886 76225 exclusion phecode
564 Functional digestive disorders Digestive 0.978 0.961 – 0.995 0.0103 14401 155892 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 0.96 0.928 – 0.994 0.0195 3608 40675 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1 0.94 – 1.06 0.989 1085 12103 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 0.984 0.965 – 1 0.132 10113 112427 exclusion phecode
565 Anal and rectal conditions Digestive 0.976 0.956 – 0.996 0.0187 10104 109185 exclusion phecode
565.1 Anal and rectal polyp Digestive 0.968 0.94 – 0.996 0.0244 5090 54001 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 0.908 0.832 – 0.99 0.0291 529 6775 exclusion phecode
568 Other disorders of peritoneum Digestive 0.971 0.928 – 1.02 0.207 2000 23868 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.958 0.914 – 1 0.0697 1906 22665 exclusion phecode
569 Other disorders of intestine Digestive 0.953 0.916 – 0.991 0.0163 2696 30730 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1 0.812 – 1.24 0.99 95 1061 exclusion phecode
569.2 Gastrointestinal complications Digestive 0.969 0.863 – 1.09 0.594 309 3579 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 0.969 0.92 – 1.02 0.236 1500 21700 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 0.935 0.874 – 1 0.0523 872 12418 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.81 0.637 – 1.03 0.0853 71 842 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 0.936 0.76 – 1.15 0.538 85 1826 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.02 0.929 – 1.11 0.732 509 7243 exclusion phecode
571.81 Portal hypertension Digestive 1.05 0.927 – 1.19 0.444 257 3917 exclusion phecode
572 Ascites (non malignant) Digestive 0.975 0.912 – 1.04 0.46 939 11265 exclusion phecode
573 Other disorders of liver Digestive 0.978 0.915 – 1.05 0.521 913 10943 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.44 1.08 – 1.92 0.0141 49 715 exclusion phecode
573.3 Hepatomegaly Digestive 1.08 0.918 – 1.27 0.357 165 2215 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 0.951 0.873 – 1.04 0.253 550 6618 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 0.972 0.93 – 1.02 0.216 2120 25434 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 0.865 0.729 – 1.03 0.0949 134 1556 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1 0.983 – 1.03 0.68 9327 113775 exclusion phecode
574.1 Cholelithiasis Digestive 0.999 0.977 – 1.02 0.957 8001 98705 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.951 0.887 – 1.02 0.153 847 10944 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.983 0.949 – 1.02 0.357 3229 39699 exclusion phecode
574.2 Calculus of bile duct Digestive 0.998 0.948 – 1.05 0.954 1546 19098 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1 0.952 – 1.05 0.943 1636 20132 exclusion phecode
575 Other biliary tract disease Digestive 1.03 0.987 – 1.07 0.171 2355 28299 exclusion phecode
575.1 Cholangitis Digestive 1 0.889 – 1.13 0.989 282 3630 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.08 0.983 – 1.18 0.112 483 5681 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 1.12 0.987 – 1.27 0.0798 272 3360 exclusion phecode
575.7 Other disorders of gallbladder Digestive 0.973 0.907 – 1.04 0.447 862 10296 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.07 0.983 – 1.16 0.117 618 7586 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1 0.869 – 1.16 0.967 205 2582 exclusion phecode
577 Diseases of pancreas Digestive 1.03 0.983 – 1.09 0.195 1623 19471 exclusion phecode
577.1 Acute pancreatitis Digestive 1.04 0.983 – 1.11 0.16 1203 14536 exclusion phecode
577.2 Chronic pancreatitis Digestive 0.993 0.883 – 1.12 0.908 298 3872 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.978 0.86 – 1.11 0.741 241 2703 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 0.978 0.962 – 0.995 0.0124 14155 152071 exclusion phecode
578.1 Hematemesis Digestive 0.996 0.938 – 1.06 0.906 1155 14543 exclusion phecode
578.2 Blood in stool Digestive 0.957 0.911 – 1.01 0.0835 1678 19280 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 0.983 0.962 – 1 0.118 9118 96388 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.959 0.927 – 0.993 0.0171 3584 38822 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.98 0.917 – 1.05 0.545 963 11318 exclusion phecode
579.2 Splenomegaly Digestive 1.09 0.949 – 1.25 0.225 229 3150 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.01 0.953 – 1.07 0.713 1170 12104 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.876 0.816 – 0.94 0.000242 812 11169 exclusion phecode
580.1 Glomerulonephritis Genitourinary 0.897 0.823 – 0.978 0.0139 544 7659 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.01 0.735 – 1.37 0.973 42 554 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.02 0.818 – 1.27 0.853 81 1006 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.886 0.806 – 0.974 0.0124 441 6338 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.882 0.776 – 1 0.0521 250 3430 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.957 0.807 – 1.14 0.618 137 1814 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.936 0.791 – 1.11 0.437 142 1860 exclusion phecode
585 Renal failure Genitourinary 0.933 0.903 – 0.964 3.2e-05 3826 51012 exclusion phecode
585.1 Acute renal failure Genitourinary 0.934 0.896 – 0.973 0.00106 2413 33029 exclusion phecode
585.2 Renal failure NOS Genitourinary 0.919 0.856 – 0.987 0.0202 802 10737 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.942 0.892 – 0.994 0.0301 1386 19282 exclusion phecode
585.31 Renal dialysis Genitourinary 0.913 0.809 – 1.03 0.14 270 3650 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 0.965 0.923 – 1.01 0.112 2098 24709 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.829 0.69 – 0.997 0.0469 115 1512 exclusion phecode
586.11 Small kidney Genitourinary 0.898 0.737 – 1.09 0.288 100 1297 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1 0.93 – 1.07 0.993 808 9233 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.749 0.555 – 1.01 0.0588 44 607 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.977 0.899 – 1.06 0.582 591 6721 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.09 0.95 – 1.24 0.226 224 2761 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.22 0.92 – 1.62 0.166 52 740 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.08 0.857 – 1.37 0.507 71 842 exclusion phecode
590 Pyelonephritis Genitourinary 0.924 0.862 – 0.991 0.0263 855 9734 exclusion phecode
591 Urinary tract infection Genitourinary 0.973 0.951 – 0.995 0.0187 7950 90451 exclusion phecode
592 Cystitis and urethritis Genitourinary 0.956 0.913 – 1 0.0579 1960 21503 exclusion phecode
592.1 Cystitis Genitourinary 0.964 0.92 – 1.01 0.119 1922 21020 exclusion phecode
592.11 Acute cystitis Genitourinary 1 0.807 – 1.24 0.999 86 1020 exclusion phecode
592.12 Chronic cystitis Genitourinary 0.949 0.873 – 1.03 0.227 587 6490 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 0.924 0.787 – 1.08 0.333 169 1795 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.812 0.673 – 0.98 0.0297 118 1227 exclusion phecode
593 Hematuria Genitourinary 0.982 0.963 – 1 0.0657 11167 118206 exclusion phecode
594 Urinary calculus Genitourinary 0.989 0.958 – 1.02 0.469 4321 47529 exclusion phecode
594.1 Calculus of kidney Genitourinary 0.975 0.933 – 1.02 0.274 2104 23572 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 0.996 0.909 – 1.09 0.929 508 5753 exclusion phecode
594.3 Calculus of ureter Genitourinary 0.988 0.939 – 1.04 0.648 1616 18026 exclusion phecode
594.8 Renal colic Genitourinary 0.994 0.941 – 1.05 0.827 1413 15359 exclusion phecode
595 Hydronephrosis Genitourinary 0.968 0.913 – 1.03 0.265 1228 14246 exclusion phecode
596 Other disorders of bladder Genitourinary 0.969 0.945 – 0.993 0.0133 6751 72012 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1 0.948 – 1.06 0.958 1459 14641 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 0.914 0.858 – 0.973 0.00466 1057 12176 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.982 0.944 – 1.02 0.365 2737 28717 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.986 0.945 – 1.03 0.528 2323 24412 exclusion phecode
597.2 Urinary complications NEC Genitourinary 0.696 0.521 – 0.93 0.0144 45 542 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1 0.964 – 1.05 0.843 2461 25865 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.959 0.826 – 1.11 0.584 177 2202 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.973 0.955 – 0.991 0.00387 12319 134990 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.876 0.72 – 1.07 0.184 104 1199 exclusion phecode
599.2 Retention of urine Genitourinary 0.946 0.918 – 0.975 0.000334 4557 49656 exclusion phecode
599.3 Dysuria Genitourinary 0.959 0.893 – 1.03 0.253 822 8951 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.952 0.926 – 0.978 0.000398 5542 63328 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 0.97 0.933 – 1.01 0.119 2801 29604 exclusion phecode
599.6 Oliguria and anuria Genitourinary 0.816 0.623 – 1.07 0.14 53 767 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.12 0.829 – 1.5 0.471 44 443 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1.03 0.97 – 1.09 0.374 1338 14207 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.99 0.967 – 1.01 0.408 8075 65776 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 0.924 0.877 – 0.974 0.00318 1514 15614 exclusion phecode
601.1 Prostatitis Genitourinary 0.91 0.858 – 0.966 0.00206 1163 11741 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.813 0.697 – 0.949 0.00848 162 1801 exclusion phecode
601.12 Chronic prostatitis Genitourinary 0.948 0.878 – 1.03 0.181 687 6850 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.855 0.624 – 1.17 0.328 45 440 exclusion phecode
601.4 Balanoposthitis Genitourinary 0.921 0.803 – 1.06 0.238 218 2155 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.966 0.833 – 1.12 0.645 183 2255 exclusion phecode
602 Other disorders of prostate Genitourinary 1 0.939 – 1.07 0.945 998 9934 exclusion phecode
603 Other disorders of testis Genitourinary 0.941 0.893 – 0.991 0.0211 1552 16339 exclusion phecode
603.1 Hydrocele Genitourinary 0.966 0.905 – 1.03 0.3 985 10151 exclusion phecode
604 Disorders of penis Genitourinary 0.953 0.914 – 0.994 0.0243 2365 24927 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.954 0.91 – 0.999 0.0439 1944 20703 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 1.1 0.952 – 1.27 0.194 199 2112 exclusion phecode
608 Other disorders of male genital organs Genitourinary 0.963 0.921 – 1.01 0.104 2094 21423 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.97 0.821 – 1.15 0.719 153 1623 exclusion phecode
609.1 Infertility, male Genitourinary 0.958 0.701 – 1.31 0.79 46 491 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.966 0.803 – 1.16 0.715 121 1275 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.979 0.933 – 1.03 0.394 1803 17872 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.943 0.872 – 1.02 0.147 679 6606 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1.06 0.927 – 1.21 0.401 224 2180 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 1.05 0.906 – 1.21 0.537 208 2150 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.997 0.934 – 1.06 0.921 1016 10041 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.945 0.86 – 1.04 0.233 474 4924 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.997 0.938 – 1.06 0.933 1117 11339 exclusion phecode
611.1 Abnormal mammogram Genitourinary 1.01 0.749 – 1.37 0.931 42 405 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.994 0.934 – 1.06 0.848 1080 10967 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.05 0.968 – 1.14 0.231 592 6547 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.04 0.953 – 1.13 0.382 562 6267 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 1.16 0.881 – 1.53 0.291 57 530 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 1.02 0.961 – 1.09 0.473 1097 11899 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.05 0.951 – 1.15 0.35 445 5179 exclusion phecode
613.5 Mastodynia Genitourinary 0.912 0.68 – 1.22 0.536 46 541 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 1.02 0.929 – 1.12 0.673 488 5001 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 0.94 0.821 – 1.08 0.374 232 2383 exclusion phecode
613.9 Breast disorder NOS Genitourinary – 158 1469 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.986 0.954 – 1.02 0.407 3783 41757 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.946 0.9 – 0.995 0.0313 1616 18615 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.923 0.845 – 1.01 0.071 529 6102 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.15 0.83 – 1.59 0.399 40 442 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.877 0.776 – 0.991 0.0359 262 3104 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.883 0.771 – 1.01 0.0719 222 2613 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.01 0.871 – 1.17 0.883 177 2027 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.03 0.979 – 1.08 0.265 1802 19001 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.01 0.945 – 1.08 0.742 896 9554 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.09 0.971 – 1.22 0.144 307 3097 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.02 0.935 – 1.11 0.641 548 5579 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.948 0.811 – 1.11 0.497 173 1998 exclusion phecode
615 Endometriosis Genitourinary 0.96 0.923 – 0.998 0.0374 2734 29717 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 0.884 0.762 – 1.03 0.106 180 2192 exclusion phecode
618 Genital prolapse Genitourinary 0.969 0.947 – 0.992 0.00801 7877 83188 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.947 0.919 – 0.975 0.000238 4854 52746 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.994 0.961 – 1.03 0.729 3756 38412 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.881 0.787 – 0.986 0.0275 325 3630 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.01 0.919 – 1.12 0.782 422 4775 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 0.999 0.974 – 1.03 0.967 6090 63128 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.94 0.859 – 1.03 0.172 494 5288 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 0.997 0.955 – 1.04 0.906 2285 23848 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.02 0.976 – 1.07 0.363 2010 20742 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.989 0.933 – 1.05 0.704 1269 12807 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.98 0.917 – 1.05 0.558 937 9698 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1.03 0.756 – 1.39 0.87 44 520 exclusion phecode
621 Endometrial hyperplasia Genitourinary 1.05 0.969 – 1.13 0.24 690 8149 exclusion phecode
622 Polyp of female genital organs Genitourinary 1 0.976 – 1.02 0.969 7174 75403 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 1 0.976 – 1.03 0.793 5260 56539 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 0.999 0.959 – 1.04 0.971 2496 24570 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 0.996 0.93 – 1.07 0.916 856 9204 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.954 0.872 – 1.04 0.304 522 5631 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.885 0.749 – 1.04 0.149 147 1719 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 0.996 0.883 – 1.12 0.946 293 3078 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.954 0.923 – 0.987 0.00626 3711 42004 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.967 0.924 – 1.01 0.14 2066 21098 exclusion phecode
625.1 Dyspareunia Genitourinary 0.891 0.831 – 0.956 0.00123 850 8711 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.984 0.965 – 1 0.111 11274 84553 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.978 0.958 – 0.999 0.0382 9798 80901 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 1.04 0.82 – 1.32 0.739 72 827 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 0.955 0.931 – 0.98 0.00035 6609 67768 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 1.01 0.952 – 1.06 0.827 1377 14478 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 1.01 0.966 – 1.05 0.786 2685 28248 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.938 0.884 – 0.996 0.0353 1140 13314 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.88 0.722 – 1.07 0.208 99 1161 exclusion phecode
626.8 Infertility, female Genitourinary 1.01 0.945 – 1.07 0.835 1043 10261 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.01 0.989 – 1.04 0.287 6941 73983 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 1.01 0.979 – 1.03 0.675 6030 64215 exclusion phecode
627.2 Symptomatic menopause Genitourinary 1.13 0.929 – 1.37 0.223 114 1329 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.01 0.939 – 1.09 0.755 746 7826 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1.07 0.923 – 1.23 0.386 209 2297 exclusion phecode
628 Ovarian cyst Genitourinary 0.979 0.944 – 1.02 0.255 3196 34925 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.01 0.979 – 1.05 0.464 4083 27349 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.03 0.966 – 1.11 0.338 913 8533 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.03 0.906 – 1.17 0.647 251 2463 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.969 0.919 – 1.02 0.231 1556 13063 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.982 0.909 – 1.06 0.652 684 6511 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.967 0.907 – 1.03 0.317 1002 9288 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.01 0.96 – 1.06 0.754 1851 15016 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 1.06 0.96 – 1.16 0.262 476 4617 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.993 0.925 – 1.07 0.841 851 8017 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 1.24 0.927 – 1.65 0.149 55 530 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.975 0.908 – 1.05 0.494 819 8410 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.978 0.855 – 1.12 0.746 234 2291 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.872 0.743 – 1.02 0.0928 156 1649 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.926 0.763 – 1.12 0.433 111 1159 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.02 0.96 – 1.09 0.46 998 9461 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.995 0.947 – 1.05 0.839 1726 15838 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.991 0.747 – 1.32 0.953 52 516 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.969 0.845 – 1.11 0.648 216 2065 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.837 0.667 – 1.05 0.123 87 889 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1 0.833 – 1.21 0.975 121 1439 exclusion phecode
650 Normal delivery Pregnancy Complications 0.993 0.943 – 1.05 0.797 1572 14404 exclusion phecode
651 Multiple gestation Pregnancy Complications 1.13 0.995 – 1.28 0.0589 278 2596 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.996 0.942 – 1.05 0.892 1382 12648 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.03 0.972 – 1.1 0.288 1089 10341 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 0.811 0.623 – 1.05 0.118 56 553 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.01 0.975 – 1.05 0.535 3386 22272 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.939 0.755 – 1.17 0.569 89 832 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 1.01 0.958 – 1.06 0.807 1844 13801 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 1.05 0.946 – 1.16 0.381 419 4005 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 1 0.97 – 1.04 0.844 4262 22153 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.03 0.98 – 1.08 0.263 2030 15916 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.16 0.965 – 1.39 0.115 133 1206 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.02 0.88 – 1.18 0.806 199 1978 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.863 0.661 – 1.13 0.278 53 477 exclusion phecode
679 Complications of in utero procedures Dermatologic 0.996 0.731 – 1.36 0.98 40 408 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 0.988 0.958 – 1.02 0.44 4310 53548 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.951 0.856 – 1.06 0.343 366 4211 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.991 0.886 – 1.11 0.87 331 3812 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.988 0.953 – 1.02 0.512 3237 40876 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.989 0.954 – 1.02 0.536 3245 40895 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.989 0.954 – 1.03 0.542 3215 40597 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 0.917 0.823 – 1.02 0.118 348 4436 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.01 0.943 – 1.09 0.726 820 9928 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 0.953 0.903 – 1.01 0.0771 1418 17023 exclusion phecode
686.3 Pilonidal cyst Dermatologic 0.892 0.805 – 0.99 0.0312 374 4447 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 0.997 0.875 – 1.14 0.965 259 2658 exclusion phecode
687 Symptoms affecting skin Dermatologic 0.965 0.866 – 1.08 0.52 353 3998 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.01 0.958 – 1.07 0.643 1341 15656 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 0.887 0.767 – 1.03 0.105 196 2049 exclusion phecode
687.3 Changes in skin texture Dermatologic 1.16 0.917 – 1.47 0.214 75 788 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 0.967 0.922 – 1.01 0.161 1884 21386 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1 0.97 – 1.03 0.902 4066 42026 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 1.1 0.817 – 1.49 0.525 45 551 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 1.01 0.721 – 1.41 0.966 33 415 exclusion phecode
691 Congenital anomalies of skin Dermatologic 1.05 0.844 – 1.3 0.668 87 854 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 1.02 0.943 – 1.1 0.645 722 7187 exclusion phecode
694.1 Vitiligo Dermatologic 1.11 0.792 – 1.55 0.545 39 447 exclusion phecode
694.2 Other dyschromia Dermatologic 1.01 0.932 – 1.1 0.747 594 5715 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 0.959 0.747 – 1.23 0.741 70 856 exclusion phecode
695 Erythematous conditions Dermatologic 0.978 0.929 – 1.03 0.401 1550 17251 exclusion phecode
695.1 Toxic erythema Dermatologic 1.08 0.844 – 1.37 0.549 70 809 exclusion phecode
695.2 Bullous dermatoses Dermatologic 0.881 0.707 – 1.1 0.258 83 971 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 0.836 0.593 – 1.18 0.307 36 406 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.852 0.633 – 1.15 0.291 45 520 exclusion phecode
695.3 Rosacea Dermatologic 0.946 0.823 – 1.09 0.432 216 2260 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 0.936 0.825 – 1.06 0.306 250 2973 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.763 0.604 – 0.963 0.023 73 939 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 0.973 0.848 – 1.12 0.701 209 2458 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 0.994 0.908 – 1.09 0.9 507 5608 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 0.936 0.8 – 1.1 0.408 161 1739 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.949 0.725 – 1.24 0.702 52 566 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.02 0.904 – 1.15 0.766 303 3382 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.954 0.901 – 1.01 0.103 1242 16631 exclusion phecode
696.4 Psoriasis Dermatologic 0.945 0.892 – 1 0.057 1203 16221 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.959 0.898 – 1.02 0.211 947 12389 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.927 0.833 – 1.03 0.162 345 5227 exclusion phecode
697 Sarcoidosis Dermatologic 1 0.893 – 1.12 0.968 322 4029 exclusion phecode
698 Pruritus and related conditions Dermatologic 0.955 0.873 – 1.04 0.305 532 5654 exclusion phecode
700 Corns and callosities Dermatologic 0.91 0.785 – 1.06 0.215 184 2061 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.969 0.935 – 1 0.0815 3255 34051 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.899 0.689 – 1.17 0.43 56 639 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.976 0.928 – 1.03 0.342 1667 17012 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.814 0.584 – 1.13 0.224 34 443 exclusion phecode
701.4 Keloid scar Dermatologic 0.923 0.782 – 1.09 0.343 147 1602 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 0.913 0.816 – 1.02 0.116 327 3370 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 0.791 0.621 – 1.01 0.0576 67 745 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.979 0.948 – 1.01 0.211 3925 39571 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.941 0.897 – 0.987 0.013 1809 18662 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 1.02 0.973 – 1.06 0.468 2262 22328 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.01 0.883 – 1.15 0.905 235 2560 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.987 0.911 – 1.07 0.757 635 7128 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.982 0.95 – 1.02 0.298 3797 39022 exclusion phecode
704.1 Alopecia Dermatologic 1.11 0.886 – 1.4 0.354 85 932 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.94 0.714 – 1.24 0.658 56 564 exclusion phecode
705 Disorders of sweat glands Dermatologic 0.976 0.809 – 1.18 0.799 111 1676 exclusion phecode
705.3 Hidradenitis Dermatologic 0.975 0.785 – 1.21 0.822 82 1382 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.03 0.93 – 1.14 0.573 391 4413 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 0.991 0.965 – 1.02 0.483 5981 61174 exclusion phecode
706.1 Acne Dermatologic 1.07 0.802 – 1.42 0.65 51 577 exclusion phecode
706.2 Sebaceous cyst Dermatologic 0.992 0.967 – 1.02 0.532 6343 64589 exclusion phecode
707 Chronic ulcer of skin Dermatologic 0.909 0.853 – 0.97 0.00381 977 14498 exclusion phecode
707.1 Decubitus ulcer Dermatologic 0.928 0.847 – 1.02 0.11 488 6679 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.972 0.932 – 1.01 0.201 2271 25004 exclusion phecode
709.2 Sicca syndrome Dermatologic 0.94 0.834 – 1.06 0.308 280 3652 exclusion phecode
709.3 Systemic sclerosis Dermatologic 0.922 0.754 – 1.13 0.426 100 1266 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.08 0.774 – 1.49 0.666 34 463 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.987 0.941 – 1.03 0.581 1861 19828 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.973 0.871 – 1.09 0.622 336 4519 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 0.971 0.865 – 1.09 0.616 305 4186 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.805 0.659 – 0.985 0.0351 105 1463 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.01 0.878 – 1.16 0.916 215 2986 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 0.891 0.782 – 1.02 0.0834 241 3164 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 0.886 0.764 – 1.03 0.106 187 2463 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 0.933 0.704 – 1.24 0.632 49 595 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.92 0.727 – 1.16 0.487 66 1135 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.03 0.687 – 1.53 0.897 22 489 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.974 0.934 – 1.02 0.218 2325 35438 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.974 0.931 – 1.02 0.241 2063 32033 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.933 0.873 – 0.997 0.0392 918 12296 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.987 0.765 – 1.27 0.92 64 847 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.912 0.81 – 1.03 0.127 278 4636 exclusion phecode
716 Other arthropathies Musculoskeletal 0.961 0.948 – 0.974 5.34e-09 23830 198024 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.927 0.886 – 0.969 0.000823 2050 25611 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.962 0.942 – 0.982 0.000198 9841 115375 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 0.961 0.947 – 0.974 9e-09 22886 195656 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.92 0.848 – 0.998 0.0445 614 8206 exclusion phecode
720 Spinal stenosis Musculoskeletal 1 0.959 – 1.04 0.99 2390 27012 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 0.974 0.946 – 1 0.0732 4871 56892 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.971 0.936 – 1.01 0.106 3141 36651 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.07 0.886 – 1.29 0.491 121 1399 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 0.874 0.763 – 1 0.052 212 2558 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 0.983 0.958 – 1.01 0.215 5933 66620 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.954 0.855 – 1.06 0.4 355 3765 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.987 0.94 – 1.04 0.594 1761 20925 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 0.776 0.583 – 1.03 0.0811 45 497 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.987 0.951 – 1.03 0.512 2947 32788 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.01 0.899 – 1.13 0.923 331 3848 exclusion phecode
723.1 Torticollis Musculoskeletal 1.07 0.836 – 1.37 0.587 67 797 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 0.999 0.946 – 1.06 0.973 1362 15183 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1.08 0.954 – 1.23 0.219 255 2974 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 1.07 0.946 – 1.22 0.276 258 2995 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.01 0.749 – 1.36 0.957 43 460 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 0.973 0.915 – 1.04 0.391 1084 11946 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.999 0.978 – 1.02 0.896 10020 108259 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.999 0.974 – 1.02 0.93 6537 70490 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.922 0.806 – 1.06 0.239 223 2458 exclusion phecode
726.3 Bursitis Musculoskeletal 1.02 0.933 – 1.11 0.717 586 6476 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.981 0.953 – 1.01 0.2 4950 53968 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.973 0.927 – 1.02 0.261 1781 20083 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.978 0.772 – 1.24 0.853 69 770 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.992 0.949 – 1.04 0.705 2201 22746 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.941 0.848 – 1.04 0.256 371 4266 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.949 0.83 – 1.09 0.448 224 2613 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.08 0.869 – 1.34 0.495 90 1049 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.96 0.923 – 0.998 0.039 2709 27185 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.05 0.933 – 1.19 0.395 278 3105 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.949 0.913 – 0.987 0.00822 2787 28074 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.955 0.918 – 0.994 0.0254 2587 25675 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 0.962 0.929 – 0.995 0.0257 3492 44195 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.961 0.879 – 1.05 0.389 514 7259 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.933 0.725 – 1.2 0.589 64 757 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.925 0.794 – 1.08 0.311 187 2015 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.919 0.787 – 1.07 0.289 176 1906 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.952 0.848 – 1.07 0.397 313 3512 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.987 0.833 – 1.17 0.884 141 1523 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.713 0.52 – 0.976 0.0348 40 434 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.02 0.964 – 1.09 0.445 1187 12910 exclusion phecode
733.2 Cyst of bone Musculoskeletal 0.96 0.836 – 1.1 0.566 220 2252 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.849 0.762 – 0.946 0.00303 356 3963 exclusion phecode
733.6 Costochondritis Musculoskeletal 0.852 0.679 – 1.07 0.165 80 926 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.988 0.921 – 1.06 0.734 837 9117 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.12 0.903 – 1.38 0.307 94 893 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1 0.978 – 1.03 0.797 6708 68829 exclusion phecode
735.1 Flat foot Musculoskeletal 1.02 0.847 – 1.23 0.84 122 1426 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 1.01 0.971 – 1.04 0.768 3415 36323 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.998 0.942 – 1.06 0.942 1273 13759 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 1.01 0.951 – 1.08 0.696 1077 11076 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.01 0.985 – 1.05 0.341 4722 47420 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1.02 0.955 – 1.08 0.585 1052 11896 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.09 0.932 – 1.29 0.272 167 1810 exclusion phecode
737 Curvature of spine Musculoskeletal 0.917 0.85 – 0.989 0.0253 720 8183 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.914 0.845 – 0.988 0.0245 677 7678 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.981 0.927 – 1.04 0.523 1259 13821 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.95 0.89 – 1.01 0.124 977 10860 exclusion phecode
739 Contracture of joint Musculoskeletal 1.01 0.906 – 1.14 0.798 330 3579 exclusion phecode
740 Osteoarthrosis Musculoskeletal 0.973 0.958 – 0.988 0.000561 17749 170156 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.982 0.963 – 1 0.0595 11279 123987 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.982 0.956 – 1.01 0.186 5712 65647 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.928 0.805 – 1.07 0.303 201 2572 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.906 0.817 – 1.01 0.0624 368 4307 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.963 0.94 – 0.985 0.00128 7634 89398 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.989 0.948 – 1.03 0.598 2336 26205 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 1.19 0.925 – 1.54 0.174 64 732 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 0.945 0.855 – 1.04 0.264 417 4558 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 1.2 0.973 – 1.49 0.0868 94 1149 exclusion phecode
741.4 Joint effusions Musculoskeletal 0.935 0.873 – 1 0.0586 871 10389 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.05 0.833 – 1.31 0.698 72 824 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 1.16 0.825 – 1.64 0.389 35 408 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.03 0.979 – 1.07 0.282 1976 21071 exclusion phecode
742.1 Loose body in joint Musculoskeletal 1.06 0.929 – 1.2 0.394 239 2487 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.05 0.825 – 1.34 0.689 72 744 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 0.999 0.891 – 1.12 0.984 327 3665 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 1.04 0.982 – 1.1 0.193 1399 14757 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.974 0.946 – 1 0.0727 5055 53872 exclusion phecode
743.1 Osteoporosis Musculoskeletal 0.976 0.946 – 1.01 0.132 4265 45434 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 0.978 0.945 – 1.01 0.192 3700 39334 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 0.97 0.867 – 1.08 0.589 331 3785 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1 0.895 – 1.13 0.95 314 3710 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.949 0.871 – 1.03 0.234 569 5837 exclusion phecode
745 Pain in joint Musculoskeletal 0.97 0.943 – 0.998 0.0384 5116 58520 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.962 0.917 – 1.01 0.11 1798 20566 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.962 0.916 – 1.01 0.128 1682 19281 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.999 0.902 – 1.11 0.981 410 4302 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.02 0.866 – 1.2 0.819 163 1721 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.941 0.886 – 1 0.05 1110 13206 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.909 0.75 – 1.1 0.331 108 1235 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.07 0.748 – 1.53 0.709 36 368 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.968 0.847 – 1.11 0.637 230 2247 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 1.03 0.934 – 1.13 0.582 455 5072 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.01 0.879 – 1.15 0.934 227 2403 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.06 0.893 – 1.26 0.5 139 1422 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.992 0.865 – 1.14 0.907 225 2649 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.12 0.942 – 1.32 0.204 150 1664 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.757 0.595 – 0.964 0.0238 67 842 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.01 0.948 – 1.08 0.747 1043 11282 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.998 0.911 – 1.09 0.96 513 5202 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.993 0.886 – 1.11 0.897 332 3331 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.06 0.912 – 1.24 0.431 170 1704 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.988 0.904 – 1.08 0.782 532 6201 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.976 0.863 – 1.1 0.699 271 3103 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.96 0.835 – 1.11 0.573 210 2463 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.974 0.848 – 1.12 0.708 221 2442 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 0.959 0.819 – 1.12 0.603 170 1891 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.895 0.753 – 1.06 0.208 140 1565 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.02 0.772 – 1.35 0.895 53 586 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.979 0.803 – 1.19 0.833 91 960 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.93 0.721 – 1.2 0.575 55 562 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.879 0.695 – 1.11 0.286 68 810 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.897 0.797 – 1.01 0.072 298 3166 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.862 0.73 – 1.02 0.0774 146 1565 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.959 0.791 – 1.16 0.667 111 1182 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.85 0.672 – 1.08 0.175 74 786 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.11 1 – 1.23 0.042 411 4381 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.969 0.737 – 1.27 0.818 56 604 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.14 1.02 – 1.29 0.0266 306 3230 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.1 0.892 – 1.35 0.375 96 1273 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.11 0.787 – 1.57 0.553 30 610 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.978 0.829 – 1.15 0.79 147 1529 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.979 0.774 – 1.24 0.857 72 675 exclusion phecode
760 Back pain Symptoms 0.966 0.943 – 0.99 0.00535 7093 81991 exclusion phecode
761 Cervicalgia Symptoms 1.02 0.96 – 1.08 0.536 1183 13248 exclusion phecode
764 Sciatica Symptoms 0.966 0.918 – 1.02 0.196 1532 17331 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.06 0.982 – 1.14 0.14 729 8595 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 0.873 0.788 – 0.967 0.00935 401 4633 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.993 0.912 – 1.08 0.863 577 6393 exclusion phecode
771.1 Swelling of limb Symptoms 0.964 0.927 – 1 0.0649 2718 33872 exclusion phecode
772 Symptoms of the muscles Symptoms 0.925 0.837 – 1.02 0.122 425 4919 exclusion phecode
773 Pain in limb Symptoms 0.951 0.92 – 0.983 0.00259 3879 45394 exclusion phecode
780 Hypothermia/Chills Symptoms 0.943 0.784 – 1.13 0.531 118 1291 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.975 0.919 – 1.03 0.398 1186 13801 exclusion phecode
782.3 Edema Symptoms 0.96 0.896 – 1.03 0.242 888 11867 exclusion phecode
782.6 Pallor and flushing Symptoms 1.09 0.908 – 1.31 0.355 126 1301 exclusion phecode
783 Fever of unknown origin Symptoms 0.969 0.931 – 1.01 0.131 2492 28796 exclusion phecode
785 Abdominal pain Symptoms 0.981 0.969 – 0.994 0.00334 27521 223896 exclusion phecode
788 Syncope and collapse Symptoms 0.99 0.965 – 1.02 0.453 6219 66355 exclusion phecode
789 Nausea and vomiting Symptoms 0.973 0.951 – 0.996 0.024 7474 84448 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 0.998 0.799 – 1.25 0.986 80 1089 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 0.707 0.524 – 0.955 0.0239 40 594 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.01 0.979 – 1.04 0.517 4303 47037 exclusion phecode
791 Gangrene Symptoms 0.902 0.803 – 1.01 0.0818 292 4124 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1.11 0.881 – 1.4 0.374 78 670 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.857 0.686 – 1.07 0.177 82 981 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.01 0.91 – 1.13 0.825 352 4131 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.03 0.829 – 1.29 0.762 95 908 exclusion phecode
797 Shock Symptoms 1.02 0.825 – 1.25 0.883 93 1127 exclusion phecode
797.1 Cardiogenic shock Symptoms 0.993 0.774 – 1.27 0.955 64 749 exclusion phecode
798 Malaise and fatigue Symptoms 0.94 0.9 – 0.981 0.00505 2198 24988 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 0.992 0.899 – 1.09 0.867 409 4351 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 0.986 0.958 – 1.02 0.369 4746 51244 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.01 0.954 – 1.07 0.706 1247 13021 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.929 0.775 – 1.11 0.427 125 1219 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.956 0.907 – 1.01 0.0958 1473 15975 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.927 0.849 – 1.01 0.0918 540 5708 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.956 0.907 – 1.01 0.0929 1498 16149 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 0.927 0.875 – 0.982 0.00968 1243 13380 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 0.986 0.9 – 1.08 0.766 506 5258 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.991 0.965 – 1.02 0.502 5972 60441 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 0.983 0.925 – 1.05 0.586 1121 12363 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.99 0.958 – 1.02 0.565 3861 37753 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.988 0.928 – 1.05 0.694 1090 11352 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 1 0.964 – 1.05 0.815 2436 24817 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.985 0.922 – 1.05 0.647 953 9977 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 0.975 0.893 – 1.06 0.571 539 5700 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.992 0.928 – 1.06 0.82 914 9584 exclusion phecode
817 Concussion Injuries & Poisonings 0.914 0.787 – 1.06 0.236 181 1815 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.989 0.888 – 1.1 0.839 360 3891 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.02 0.975 – 1.07 0.408 2130 22199 exclusion phecode
823 Torus fracture Injuries & Poisonings 0.944 0.889 – 1 0.0595 1160 12384 exclusion phecode
830 Dislocation Injuries & Poisonings 1.02 0.967 – 1.08 0.476 1499 15585 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 1 0.983 – 1.02 0.782 10883 113116 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.919 0.826 – 1.02 0.115 364 3924 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.988 0.887 – 1.1 0.827 355 3561 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.979 0.946 – 1.01 0.229 3552 38720 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.11 0.9 – 1.37 0.329 104 1138 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 0.832 0.739 – 0.938 0.00259 276 3695 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.959 0.903 – 1.02 0.172 1122 13436 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.946 0.881 – 1.02 0.126 796 9161 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.973 0.929 – 1.02 0.253 1925 22982 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 0.987 0.943 – 1.03 0.558 2022 23898 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 0.866 0.641 – 1.17 0.348 43 509 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.997 0.957 – 1.04 0.904 2425 26025 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.943 0.811 – 1.1 0.448 182 2036 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 0.992 0.838 – 1.17 0.927 146 1473 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.01 0.961 – 1.05 0.799 2003 21542 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.957 0.814 – 1.13 0.599 161 1600 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.986 0.744 – 1.31 0.921 50 512 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.02 0.983 – 1.06 0.286 2946 30437 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.837 0.598 – 1.17 0.3 41 401 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.03 0.786 – 1.34 0.854 56 677 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.883 0.734 – 1.06 0.186 121 1341 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.02 0.913 – 1.13 0.764 353 3567 exclusion phecode
873 Broken tooth Injuries & Poisonings 0.926 0.787 – 1.09 0.35 155 1666 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 0.899 0.729 – 1.11 0.316 97 1298 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.03 0.847 – 1.26 0.75 111 1180 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 0.973 0.908 – 1.04 0.435 885 9732 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 0.964 0.928 – 1 0.0621 2829 31521 exclusion phecode
916 Contusion Injuries & Poisonings 0.983 0.921 – 1.05 0.613 978 10733 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.874 0.731 – 1.04 0.138 124 1308 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.97 0.858 – 1.1 0.62 279 2809 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 1.02 0.876 – 1.18 0.815 185 1810 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.992 0.939 – 1.05 0.776 1353 15316 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.972 0.826 – 1.14 0.73 158 1630 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.05 0.812 – 1.36 0.714 60 779 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1 0.896 – 1.12 0.976 326 4033 exclusion phecode
947 Urticaria Injuries & Poisonings 0.957 0.841 – 1.09 0.504 244 2705 exclusion phecode
949 Allergies, other Injuries & Poisonings 0.918 0.806 – 1.05 0.201 244 2973 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.02 0.912 – 1.15 0.683 308 3134 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.884 0.756 – 1.04 0.126 165 1937 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.844 0.755 – 0.943 0.0028 315 3654 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 0.823 0.592 – 1.14 0.246 37 404 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.01 0.76 – 1.35 0.931 46 567 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.965 0.947 – 0.984 0.000232 11843 133082 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.964 0.945 – 0.984 0.000362 10372 116717 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 0.945 0.832 – 1.07 0.38 250 3045 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.01 0.927 – 1.1 0.814 559 6354 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.93 0.812 – 1.07 0.299 219 2756 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 0.916 0.797 – 1.05 0.218 211 2690 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.998 0.832 – 1.2 0.979 126 1641 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.782 0.664 – 0.92 0.00304 147 2139 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.755 0.639 – 0.891 0.000878 143 2079 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.976 0.945 – 1.01 0.157 3827 44763 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.993 0.921 – 1.07 0.865 741 8312 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.94 0.833 – 1.06 0.317 297 3532 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.956 0.844 – 1.08 0.483 271 2969 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.9 0.803 – 1.01 0.0705 318 3821 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.02 0.916 – 1.13 0.774 386 4223 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 0.98 0.924 – 1.04 0.506 1209 14647 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.876 0.728 – 1.05 0.159 128 1435 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.915 0.781 – 1.07 0.267 165 2038 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.929 0.707 – 1.22 0.596 56 646 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.02 0.802 – 1.3 0.874 64 782 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.644 0.49 – 0.846 0.00157 51 772 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.16 0.843 – 1.6 0.358 38 473 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.959 0.679 – 1.35 0.81 33 422 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.973 0.821 – 1.15 0.754 142 1698 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 0.969 0.877 – 1.07 0.532 425 5153 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1 0.839 – 1.2 0.972 134 1497 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.02 0.758 – 1.37 0.898 48 463 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.01 0.792 – 1.3 0.909 66 779 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.83 0.669 – 1.03 0.0915 83 841 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.857 0.658 – 1.12 0.252 58 657 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.02 0.976 – 1.07 0.36 2012 22630 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1 0.952 – 1.05 0.996 1743 22015 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1 0.952 – 1.05 0.996 1743 22015 exclusion phecode
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