Departments of Anesthesiology and Biostatistics | University of Michigan

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Compare evaluated PRS models, inspect score-level performance, and follow results into PheWAS analyses.

Scores Estimated glomerular filtration rate based on creatinine UK Biobank (UKB) PheWAS analysis

Estimated glomerular filtration rate based on creatinine — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID exprsweb-egfr-creatine-ckdgen-1000genomes-discoverymeta-egfrcrea-prscs-ukb-20211120Legacy PRSCSPRS-CSLarge GWAS

Evaluation cohort: UK Biobank (UKB).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: study-defined normal-range subset.

For this ExPRS, the exclusion sensitivity scan keeps only the study-defined normal-range subset for Estimated glomerular filtration rate based on creatinine before rerunning the PheWAS. The preserved release does not include numeric bounds for this trait. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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Signal overview

The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.

167 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.01 0.99 – 1.03 0.301 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 1.01 0.968 – 1.05 0.739 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.03 0.953 – 1.12 0.442 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 1.01 0.943 – 1.09 0.74 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 0.924 0.706 – 1.21 0.565 55 550 all phecode
010 Tuberculosis Infectious Diseases 1.1 0.932 – 1.29 0.265 166 1659 all phecode
038 Septicemia Infectious Diseases 0.998 0.967 – 1.03 0.917 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.01 0.938 – 1.08 0.839 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.05 0.954 – 1.15 0.339 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 0.987 0.968 – 1.01 0.168 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.01 0.97 – 1.04 0.73 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 0.991 0.942 – 1.04 0.74 1641 16433 all phecode
041.4 E. coli Infectious Diseases 0.974 0.936 – 1.01 0.185 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 0.985 0.892 – 1.09 0.773 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.962 0.778 – 1.19 0.721 95 949 all phecode
054 Herpes simplex Infectious Diseases 0.92 0.799 – 1.06 0.252 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 0.966 0.888 – 1.05 0.421 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 0.98 0.774 – 1.24 0.865 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 0.943 0.795 – 1.12 0.504 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 0.892 0.783 – 1.02 0.0861 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.08 0.953 – 1.22 0.233 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.15 1.04 – 1.27 0.00506 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.22 1.03 – 1.44 0.024 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.25 1.03 – 1.52 0.0251 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 0.994 0.932 – 1.06 0.867 1004 10036 all phecode
079 Viral infection Infectious Diseases 0.994 0.956 – 1.03 0.764 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 1.17 0.899 – 1.53 0.242 64 640 all phecode
080 Postoperative infection Infectious Diseases 0.977 0.947 – 1.01 0.141 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 0.96 0.921 – 1 0.0551 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.01 0.78 – 1.3 0.961 71 709 all phecode
1000 Burns Injuries & Poisonings 1.01 0.928 – 1.1 0.792 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 1 0.942 – 1.06 0.996 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.02 0.995 – 1.05 0.107 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 0.93 0.825 – 1.05 0.231 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 0.978 0.926 – 1.03 0.416 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 0.971 0.851 – 1.11 0.656 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 0.927 0.815 – 1.05 0.242 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 0.989 0.927 – 1.06 0.742 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 0.985 0.963 – 1.01 0.173 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 1.02 0.994 – 1.05 0.137 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.983 0.962 – 1 0.127 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 0.972 0.792 – 1.19 0.789 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 0.966 0.86 – 1.08 0.558 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.01 0.783 – 1.3 0.947 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 0.981 0.951 – 1.01 0.248 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 0.989 0.973 – 1.01 0.178 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.05 0.929 – 1.19 0.425 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 1.07 0.943 – 1.21 0.299 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.12 0.882 – 1.43 0.35 74 756 all phecode
110.12 Althete's foot Infectious Diseases 1.03 0.865 – 1.21 0.776 141 1410 all phecode
112 Candidiasis Infectious Diseases 1 0.958 – 1.05 0.964 2126 21275 all phecode
117 Mycoses Infectious Diseases 1.06 0.938 – 1.2 0.342 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 1.16 0.989 – 1.36 0.0681 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 0.891 0.704 – 1.13 0.335 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 1.09 0.854 – 1.39 0.494 69 689 all phecode
134 Helminthiases Infectious Diseases 0.975 0.814 – 1.17 0.782 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 0.938 0.768 – 1.15 0.535 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.01 0.88 – 1.16 0.868 205 2050 all phecode
145 Cancer of mouth Neoplasms 1.02 0.941 – 1.11 0.633 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 1.01 0.897 – 1.13 0.9 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 0.994 0.815 – 1.21 0.954 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.01 0.758 – 1.34 0.962 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.972 0.896 – 1.05 0.499 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 0.947 0.833 – 1.08 0.402 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 0.973 0.857 – 1.1 0.672 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.998 0.758 – 1.32 0.99 57 570 all phecode
150 Cancer of esophagus Neoplasms 1 0.931 – 1.08 0.96 762 7630 all phecode
151 Cancer of stomach Neoplasms 0.956 0.878 – 1.04 0.305 569 5696 all phecode
153 Colorectal cancer Neoplasms 0.976 0.947 – 1.01 0.119 4580 45799 all phecode
153.2 Colon cancer Neoplasms 0.965 0.929 – 1 0.0576 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.993 0.95 – 1.04 0.759 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.926 0.836 – 1.03 0.14 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.859 0.731 – 1.01 0.0664 158 1580 all phecode
157 Pancreatic cancer Neoplasms 1.02 0.94 – 1.1 0.653 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.944 0.886 – 1.01 0.0716 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.969 0.943 – 0.997 0.0276 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.956 0.827 – 1.1 0.539 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.969 0.838 – 1.12 0.672 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.91 0.786 – 1.05 0.204 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 0.994 0.77 – 1.28 0.963 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 0.982 0.945 – 1.02 0.368 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 0.97 0.928 – 1.01 0.168 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.996 0.902 – 1.1 0.939 437 4364 all phecode
170.1 Bone cancer Neoplasms 1.03 0.855 – 1.23 0.788 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 0.983 0.877 – 1.1 0.762 331 3303 all phecode
172 Skin cancer Neoplasms 0.997 0.98 – 1.02 0.757 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.988 0.949 – 1.03 0.537 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 0.986 0.948 – 1.03 0.47 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.995 0.976 – 1.01 0.612 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.06 0.977 – 1.15 0.164 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.956 0.821 – 1.11 0.558 181 1818 all phecode
174 Breast cancer Neoplasms 0.984 0.966 – 1 0.0855 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 0.985 0.967 – 1 0.119 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.988 0.97 – 1.01 0.229 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.877 0.729 – 1.06 0.165 115 1148 all phecode
175 Acquired absence of breast Neoplasms 0.949 0.91 – 0.989 0.0137 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 0.964 0.923 – 1.01 0.106 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 0.94 0.83 – 1.06 0.332 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.968 0.925 – 1.01 0.154 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 0.973 0.919 – 1.03 0.34 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 0.983 0.93 – 1.04 0.541 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.97 0.908 – 1.04 0.361 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.966 0.904 – 1.03 0.313 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.03 0.916 – 1.16 0.606 305 3049 all phecode
185 Cancer of prostate Neoplasms 0.997 0.971 – 1.02 0.853 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 1.01 0.914 – 1.11 0.869 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.15 0.893 – 1.47 0.282 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 1.04 0.916 – 1.17 0.579 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.847 0.699 – 1.03 0.0917 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1 0.969 – 1.03 0.994 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.961 0.902 – 1.02 0.22 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.958 0.897 – 1.02 0.191 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.977 0.76 – 1.26 0.859 66 660 all phecode
189.2 Cancer of bladder Neoplasms 1 0.959 – 1.04 0.996 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.999 0.956 – 1.04 0.972 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.11 0.933 – 1.33 0.236 144 1439 all phecode
190 Cancer of eye Neoplasms 0.885 0.761 – 1.03 0.116 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.982 0.908 – 1.06 0.652 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 0.988 0.906 – 1.08 0.777 566 5650 all phecode
191.11 Cancer of brain Neoplasms 0.976 0.893 – 1.07 0.586 525 5240 all phecode
193 Thyroid cancer Neoplasms 0.927 0.831 – 1.04 0.179 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 1.09 0.885 – 1.33 0.429 95 949 all phecode
195 Cancer, suspected or other Neoplasms 0.987 0.971 – 1 0.0935 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 0.987 0.971 – 1 0.102 16267 159497 all phecode
197 Chemotherapy Neoplasms 0.988 0.975 – 1 0.105 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 0.989 0.968 – 1.01 0.288 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.992 0.965 – 1.02 0.578 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.02 0.972 – 1.06 0.49 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.986 0.936 – 1.04 0.598 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 0.981 0.942 – 1.02 0.337 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.997 0.929 – 1.07 0.942 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.02 0.976 – 1.07 0.37 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.97 0.837 – 1.12 0.686 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.01 0.961 – 1.07 0.602 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 1.13 0.916 – 1.38 0.261 95 950 all phecode
200 Myeloproliferative disease Neoplasms 1.02 0.952 – 1.09 0.616 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 0.954 0.857 – 1.06 0.385 387 3867 all phecode
201 Hodgkin's disease Neoplasms 1.1 0.967 – 1.25 0.148 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.04 0.995 – 1.08 0.0851 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.06 1.01 – 1.11 0.0176 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 1.09 0.98 – 1.21 0.111 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 1.07 0.985 – 1.17 0.109 581 5824 all phecode
204 Leukemia Neoplasms 1.03 0.976 – 1.08 0.306 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 1.03 0.948 – 1.13 0.454 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.24 0.941 – 1.63 0.127 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.04 0.948 – 1.14 0.413 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 1.02 0.928 – 1.12 0.668 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 1.05 0.933 – 1.17 0.44 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.949 0.801 – 1.12 0.541 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 1.04 0.951 – 1.13 0.407 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 0.982 0.968 – 0.997 0.0164 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.937 0.877 – 1 0.0514 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.973 0.946 – 1 0.0584 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.12 1 – 1.25 0.0469 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.974 0.866 – 1.1 0.664 318 3187 all phecode
214 Lipoma Neoplasms 0.971 0.946 – 0.996 0.0255 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.978 0.948 – 1.01 0.145 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.04 0.977 – 1.11 0.224 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 0.993 0.97 – 1.02 0.588 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.933 0.859 – 1.01 0.101 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 0.936 0.859 – 1.02 0.129 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 0.98 0.96 – 1 0.0492 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 0.975 0.956 – 0.995 0.0159 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.993 0.89 – 1.11 0.899 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 0.986 0.935 – 1.04 0.602 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.02 0.889 – 1.17 0.773 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 1.06 0.902 – 1.25 0.462 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.961 0.818 – 1.13 0.628 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 1.01 0.844 – 1.22 0.89 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.871 0.674 – 1.12 0.29 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.02 0.949 – 1.1 0.584 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.02 0.952 – 1.1 0.518 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.06 0.809 – 1.38 0.679 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.983 0.867 – 1.11 0.786 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.999 0.931 – 1.07 0.974 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.974 0.838 – 1.13 0.729 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.979 0.879 – 1.09 0.694 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.04 0.924 – 1.17 0.499 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.977 0.928 – 1.03 0.382 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.991 0.95 – 1.03 0.657 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.936 0.861 – 1.02 0.12 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.911 0.857 – 0.969 0.00316 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.9 0.818 – 0.99 0.0301 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.926 0.855 – 1 0.0555 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.05 0.999 – 1.1 0.0524 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 1.05 0.953 – 1.15 0.327 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 0.807 0.657 – 0.992 0.0414 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.14 0.957 – 1.35 0.145 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 1.03 1.01 – 1.04 0.00261 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.976 0.918 – 1.04 0.449 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.08 0.89 – 1.32 0.424 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.03 1.01 – 1.05 0.000492 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 0.962 0.852 – 1.09 0.525 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.944 0.82 – 1.09 0.418 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.935 0.812 – 1.08 0.355 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 0.995 0.898 – 1.1 0.927 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 0.981 0.966 – 0.995 0.00971 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.02 0.984 – 1.06 0.243 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.02 0.895 – 1.17 0.756 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.26 1.01 – 1.59 0.0451 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.05 0.953 – 1.15 0.347 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.04 0.889 – 1.23 0.602 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.977 0.962 – 0.993 0.00378 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.867 0.713 – 1.06 0.154 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.06 0.915 – 1.23 0.44 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.971 0.909 – 1.04 0.367 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 0.975 0.892 – 1.07 0.585 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 0.977 0.902 – 1.06 0.568 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.01 0.887 – 1.14 0.914 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.933 0.843 – 1.03 0.18 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.14 0.958 – 1.36 0.139 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.934 0.837 – 1.04 0.226 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.01 0.951 – 1.06 0.833 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.01 0.948 – 1.08 0.688 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.01 0.941 – 1.08 0.815 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.01 0.943 – 1.09 0.701 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.985 0.831 – 1.17 0.866 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.969 0.895 – 1.05 0.435 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.953 0.818 – 1.11 0.535 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.95 0.772 – 1.17 0.627 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.963 0.847 – 1.09 0.565 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.939 0.755 – 1.17 0.574 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.1 0.938 – 1.3 0.232 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.905 0.834 – 0.983 0.0184 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.853 0.731 – 0.995 0.0435 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.935 0.764 – 1.14 0.511 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.815 0.64 – 1.04 0.0986 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.955 0.856 – 1.06 0.402 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.954 0.856 – 1.06 0.399 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 0.93 0.814 – 1.06 0.28 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.909 0.789 – 1.05 0.187 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 1.03 0.875 – 1.22 0.713 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.03 0.868 – 1.22 0.755 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.14 0.932 – 1.39 0.206 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 0.902 0.761 – 1.07 0.238 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.14 0.983 – 1.31 0.0829 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 0.937 0.705 – 1.25 0.655 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 0.967 0.9 – 1.04 0.357 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.02 0.963 – 1.08 0.48 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.03 0.959 – 1.11 0.389 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.05 0.954 – 1.16 0.314 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.27 1.01 – 1.59 0.0443 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.981 0.858 – 1.12 0.779 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 1.04 0.93 – 1.16 0.495 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.985 0.875 – 1.11 0.806 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.01 0.888 – 1.15 0.896 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.03 0.891 – 1.2 0.657 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.13 0.937 – 1.37 0.2 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.939 0.734 – 1.2 0.618 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.9 0.77 – 1.05 0.191 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.89 0.752 – 1.05 0.173 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.998 0.986 – 1.01 0.701 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.998 0.987 – 1.01 0.758 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.999 0.988 – 1.01 0.928 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.11 0.847 – 1.46 0.441 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.938 0.802 – 1.1 0.416 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.988 0.858 – 1.14 0.865 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.03 0.997 – 1.07 0.0752 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 1.03 0.997 – 1.07 0.071 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.14 0.942 – 1.38 0.179 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1 0.925 – 1.09 0.93 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.01 0.924 – 1.1 0.892 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.974 0.931 – 1.02 0.245 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.883 0.814 – 0.958 0.00279 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 0.91 0.819 – 1.01 0.0813 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.05 0.987 – 1.11 0.128 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.06 0.911 – 1.24 0.446 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 0.996 0.972 – 1.02 0.759 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1 0.97 – 1.03 0.909 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.983 0.862 – 1.12 0.797 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.01 0.961 – 1.06 0.733 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.07 1 – 1.14 0.0429 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 0.947 0.897 – 1 0.0535 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.969 0.912 – 1.03 0.314 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 0.953 0.895 – 1.02 0.141 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 1.16 0.951 – 1.4 0.146 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.01 0.971 – 1.05 0.647 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 0.983 0.892 – 1.08 0.733 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 1.05 0.87 – 1.27 0.597 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.03 0.962 – 1.1 0.396 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.09 0.974 – 1.21 0.135 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.08 0.947 – 1.24 0.242 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.1 0.82 – 1.47 0.533 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.98 0.961 – 1 0.0457 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 0.979 0.96 – 0.999 0.0369 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 1.09 0.877 – 1.37 0.425 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.997 0.762 – 1.3 0.981 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.09 0.958 – 1.24 0.19 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1.16 1.01 – 1.34 0.0384 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.2 1.01 – 1.43 0.0403 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 0.964 0.845 – 1.1 0.583 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 0.988 0.965 – 1.01 0.326 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.993 0.969 – 1.02 0.553 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.933 0.846 – 1.03 0.163 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 0.989 0.93 – 1.05 0.709 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 0.988 0.929 – 1.05 0.708 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 0.985 0.915 – 1.06 0.683 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.982 0.843 – 1.14 0.818 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 0.933 0.804 – 1.08 0.364 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 1.06 0.82 – 1.38 0.639 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.06 0.902 – 1.25 0.465 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 0.936 0.718 – 1.22 0.627 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.01 0.815 – 1.25 0.943 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.11 0.927 – 1.32 0.266 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1.09 0.896 – 1.33 0.384 103 1059 all phecode
284 Aplastic anemia Hematopoietic 1.06 0.956 – 1.17 0.282 435 4357 all phecode
285 Other anemias Hematopoietic 1.01 0.987 – 1.02 0.542 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.01 0.892 – 1.15 0.864 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.05 0.969 – 1.13 0.245 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.03 0.931 – 1.14 0.562 414 4147 all phecode
286 Coagulation defects Hematopoietic 1.01 0.948 – 1.09 0.676 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 1 0.907 – 1.1 0.998 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 0.974 0.793 – 1.19 0.797 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.987 0.874 – 1.11 0.83 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.21 0.936 – 1.55 0.147 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.2 0.953 – 1.5 0.122 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.05 0.947 – 1.17 0.35 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.02 0.966 – 1.07 0.535 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.05 0.886 – 1.25 0.561 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 1.08 0.817 – 1.44 0.575 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 1 0.951 – 1.06 0.937 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.02 0.926 – 1.13 0.651 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.781 0.618 – 0.986 0.0377 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 1.02 0.987 – 1.06 0.238 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 1.03 0.993 – 1.07 0.117 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 1.03 0.993 – 1.07 0.116 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 1.11 0.877 – 1.42 0.376 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.957 0.893 – 1.03 0.222 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.08 0.957 – 1.22 0.212 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 0.994 0.955 – 1.04 0.771 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 1.01 0.923 – 1.11 0.829 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.02 0.905 – 1.15 0.745 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 0.896 0.717 – 1.12 0.336 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.96 0.916 – 1.01 0.088 1929 19281 all phecode
290.1 Dementias Mental Disorders 0.956 0.896 – 1.02 0.18 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 1.01 0.915 – 1.12 0.824 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 1 0.871 – 1.15 0.97 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.978 0.903 – 1.06 0.593 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.867 0.673 – 1.12 0.267 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.966 0.9 – 1.04 0.335 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.08 0.905 – 1.3 0.38 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.942 0.836 – 1.06 0.328 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 0.943 0.855 – 1.04 0.235 436 4376 all phecode
292 Neurological disorders Mental Disorders 0.975 0.946 – 1 0.0961 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1 0.949 – 1.05 0.999 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.966 0.832 – 1.12 0.647 190 1907 all phecode
292.3 Memory loss Mental Disorders 0.963 0.89 – 1.04 0.347 696 6978 all phecode
292.4 Altered mental status Mental Disorders 0.942 0.901 – 0.984 0.00751 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 1 0.89 – 1.13 0.987 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 0.984 0.94 – 1.03 0.481 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.96 0.897 – 1.03 0.239 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.949 0.884 – 1.02 0.153 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 0.928 0.85 – 1.01 0.0911 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 1.05 0.9 – 1.22 0.538 178 1780 all phecode
295.3 Psychosis Mental Disorders 1.01 0.86 – 1.18 0.945 169 1710 all phecode
296 Mood disorders Mental Disorders 0.978 0.96 – 0.996 0.0164 12372 123822 all phecode
296.1 Bipolar Mental Disorders 0.99 0.93 – 1.05 0.761 1059 10599 all phecode
296.2 Depression Mental Disorders 0.975 0.957 – 0.994 0.00921 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 0.942 0.845 – 1.05 0.277 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.938 0.836 – 1.05 0.27 311 3070 all phecode
300 Anxiety disorders Mental Disorders 0.987 0.962 – 1.01 0.292 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 0.983 0.958 – 1.01 0.203 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1.04 0.876 – 1.23 0.666 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.01 0.931 – 1.09 0.877 707 7065 all phecode
300.13 Phobia Mental Disorders 0.979 0.893 – 1.07 0.645 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.07 0.903 – 1.27 0.426 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 0.952 0.712 – 1.27 0.742 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 1.12 0.936 – 1.34 0.214 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.01 0.83 – 1.23 0.905 113 1129 all phecode
301 Personality disorders Mental Disorders 1.09 0.977 – 1.22 0.119 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.12 0.934 – 1.35 0.22 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.903 0.799 – 1.02 0.103 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.02 0.923 – 1.12 0.753 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 1.03 0.922 – 1.15 0.606 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 0.981 0.817 – 1.18 0.84 123 1229 all phecode
304 Adjustment reaction Mental Disorders 0.927 0.822 – 1.04 0.214 293 2936 all phecode
305.2 Eating disorder Mental Disorders 0.847 0.676 – 1.06 0.149 90 900 all phecode
306 Other mental disorder Mental Disorders 0.969 0.957 – 0.981 6.86e-07 28056 230087 all phecode
306.9 Tension headache Mental Disorders 0.856 0.764 – 0.959 0.00714 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 0.967 0.771 – 1.21 0.771 76 770 all phecode
313.3 Autism Mental Disorders 1.04 0.796 – 1.36 0.763 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 0.994 0.889 – 1.11 0.916 351 3517 all phecode
315.1 Learning disorder Mental Disorders 0.938 0.797 – 1.1 0.439 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 1 0.803 – 1.25 0.989 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 0.946 0.919 – 0.973 0.000117 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.973 0.753 – 1.26 0.836 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 0.973 0.956 – 0.991 0.0037 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 0.977 0.956 – 0.999 0.0409 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 0.926 0.863 – 0.994 0.0341 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 0.952 0.938 – 0.966 1.02e-10 19359 185465 all phecode
320 Meningitis Neurological 0.942 0.854 – 1.04 0.231 444 4447 all phecode
323 Encephalitis Neurological 1.08 0.972 – 1.21 0.148 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 1.04 0.832 – 1.3 0.728 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 0.894 0.793 – 1.01 0.0705 292 2916 all phecode
327 Sleep disorders Neurological 1.01 0.948 – 1.07 0.826 1164 11659 all phecode
327.3 Sleep apnea Neurological 1.01 0.977 – 1.04 0.624 4428 44318 all phecode
327.4 Insomnia Neurological 1.03 0.883 – 1.21 0.689 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 1.06 0.897 – 1.26 0.485 136 1390 all phecode
331 Other cerebral degenerations Neurological 0.989 0.93 – 1.05 0.721 1142 11416 all phecode
331.1 Hydrocephalus Neurological 0.996 0.908 – 1.09 0.924 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 0.995 0.901 – 1.1 0.924 430 4298 all phecode
332 Parkinson's disease Neurological 0.975 0.917 – 1.04 0.415 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.949 0.886 – 1.02 0.14 894 8954 all phecode
333.1 Essential tremor Neurological 0.973 0.846 – 1.12 0.701 216 2157 all phecode
333.2 Myoclonus Neurological 1.15 0.935 – 1.42 0.182 96 958 all phecode
333.4 Torsion dystonia Neurological 0.908 0.799 – 1.03 0.144 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 0.996 0.948 – 1.05 0.863 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 0.983 0.813 – 1.19 0.862 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 0.959 0.839 – 1.1 0.535 245 2446 all phecode
335 Multiple sclerosis Neurological 1.01 0.954 – 1.07 0.735 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 0.934 0.825 – 1.06 0.278 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 0.813 0.635 – 1.04 0.0995 72 719 all phecode
338 Pain Neurological 0.935 0.867 – 1.01 0.08 768 7692 all phecode
338.1 Acute pain Neurological 0.911 0.82 – 1.01 0.0813 394 3937 all phecode
338.2 Chronic pain Neurological 0.946 0.849 – 1.05 0.313 380 3817 all phecode
339 Other headache syndromes Neurological 0.992 0.969 – 1.02 0.48 7819 78241 all phecode
340 Migraine Neurological 0.993 0.955 – 1.03 0.711 2860 28602 all phecode
340.1 Migrain with aura Neurological 1.02 0.885 – 1.18 0.761 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.1 0.962 – 1.25 0.167 252 2535 all phecode
342 Hemiplegia Neurological 0.951 0.902 – 1 0.0666 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 1.06 0.894 – 1.27 0.485 145 1450 all phecode
344 Other paralytic syndromes Neurological 1.06 0.973 – 1.14 0.193 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.984 0.956 – 1.01 0.292 5023 50270 all phecode
345.1 Epilepsy Neurological 0.962 0.896 – 1.03 0.281 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 0.982 0.89 – 1.08 0.716 439 4385 all phecode
345.12 Partial epilepsy Neurological 0.926 0.817 – 1.05 0.228 277 2776 all phecode
345.3 Convulsions Neurological 0.993 0.951 – 1.04 0.769 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.941 0.798 – 1.11 0.471 144 1438 all phecode
348 Other conditions of brain Neurological 1.05 0.973 – 1.13 0.222 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.11 0.98 – 1.26 0.1 268 2678 all phecode
348.4 Cerebral cysts Neurological 0.972 0.813 – 1.16 0.754 133 1350 all phecode
348.7 Coma Neurological 0.99 0.89 – 1.1 0.857 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.02 0.895 – 1.16 0.762 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 0.936 0.844 – 1.04 0.215 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.989 0.885 – 1.1 0.839 342 3414 all phecode
350 Abnormal movement Neurological 0.967 0.929 – 1.01 0.0982 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 0.993 0.926 – 1.06 0.836 887 8852 all phecode
350.2 Abnormality of gait Neurological 0.948 0.9 – 0.998 0.0432 1596 15969 all phecode
350.3 Lack of coordination Neurological 0.964 0.866 – 1.07 0.51 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.91 0.689 – 1.2 0.506 54 540 all phecode
351 Other peripheral nerve disorders Neurological 0.997 0.979 – 1.02 0.765 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 1.04 0.988 – 1.1 0.123 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.07 0.973 – 1.18 0.164 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.02 0.95 – 1.09 0.624 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 0.982 0.924 – 1.04 0.568 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 0.913 0.759 – 1.1 0.337 114 1138 all phecode
353.2 Nerve root lesions Neurological 1.14 0.866 – 1.49 0.357 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.943 0.796 – 1.12 0.504 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.04 0.984 – 1.1 0.167 1361 13648 all phecode
358 Myoneural disorders Neurological 1.05 0.915 – 1.21 0.466 211 2109 all phecode
358.1 Myasthenia gravis Neurological 1.04 0.902 – 1.21 0.568 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 1.08 0.981 – 1.19 0.117 465 4646 all phecode
359.1 Muscular dystrophies Neurological 1.04 0.864 – 1.24 0.706 122 1219 all phecode
359.2 Myopathy Neurological 1.08 0.966 – 1.2 0.18 360 3597 all phecode
360 Disorders of the globe Sense Organs 1.07 0.957 – 1.19 0.237 337 3367 all phecode
360.2 Progressive myopia Sense Organs 1.1 0.969 – 1.26 0.135 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 1.02 0.98 – 1.05 0.389 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.01 0.956 – 1.07 0.728 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.975 0.762 – 1.25 0.84 68 680 all phecode
362 Other retinal disorders Sense Organs 0.971 0.939 – 1 0.0845 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.964 0.923 – 1.01 0.107 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.965 0.923 – 1.01 0.112 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.23 1.04 – 1.44 0.0135 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 1.21 0.977 – 1.49 0.0808 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.967 0.901 – 1.04 0.342 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.943 0.808 – 1.1 0.451 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.901 0.712 – 1.14 0.383 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.855 0.708 – 1.03 0.103 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.02 0.865 – 1.2 0.828 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 0.991 0.772 – 1.27 0.946 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.965 0.89 – 1.05 0.382 647 6485 all phecode
364.1 Corneal opacity Sense Organs 1.02 0.828 – 1.26 0.853 90 910 all phecode
364.2 Corneal edema Sense Organs 0.746 0.582 – 0.954 0.0198 79 800 all phecode
364.4 Corneal degenerations Sense Organs 0.999 0.864 – 1.15 0.985 201 2017 all phecode
364.41 Keratoconus Sense Organs 1.02 0.82 – 1.26 0.882 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 0.997 0.867 – 1.15 0.971 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.894 0.73 – 1.09 0.278 100 1000 all phecode
365 Glaucoma Sense Organs 0.961 0.931 – 0.991 0.0112 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 0.961 0.901 – 1.02 0.224 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 0.958 0.898 – 1.02 0.193 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.02 0.94 – 1.1 0.691 698 6996 all phecode
366 Cataract Sense Organs 0.996 0.981 – 1.01 0.588 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 0.973 0.757 – 1.25 0.832 69 700 all phecode
366.2 Senile cataract Sense Organs 0.994 0.972 – 1.02 0.615 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 1.24 1.01 – 1.51 0.0419 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.03 0.986 – 1.07 0.191 2408 24092 all phecode
367.1 Myopia Sense Organs 1.01 0.955 – 1.07 0.675 1251 12519 all phecode
367.2 Astigmatism Sense Organs 1.04 0.903 – 1.21 0.557 190 1899 all phecode
367.8 Hypermetropia Sense Organs 0.969 0.853 – 1.1 0.633 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 1.07 0.988 – 1.15 0.101 719 7198 all phecode
368 Visual disturbances Sense Organs 0.999 0.962 – 1.04 0.964 2962 29648 all phecode
368.1 Amblyopia Sense Organs 0.977 0.893 – 1.07 0.606 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.03 0.957 – 1.11 0.407 727 7288 all phecode
368.3 Anisometropia Sense Organs 1.1 0.929 – 1.29 0.275 154 1548 all phecode
368.4 Visual field defects Sense Organs 1.14 1.01 – 1.28 0.0271 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 0.999 0.92 – 1.09 0.983 612 6115 all phecode
369 Infection of the eye Sense Organs 1.04 0.956 – 1.14 0.346 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 1.03 0.866 – 1.22 0.741 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 1.02 0.891 – 1.17 0.767 213 2128 all phecode
370 Keratitis Sense Organs 0.914 0.808 – 1.03 0.155 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 0.799 0.673 – 0.95 0.0108 141 1408 all phecode
371 Inflammation of the eye Sense Organs 1.03 0.989 – 1.07 0.162 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.02 0.927 – 1.12 0.716 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 1.02 0.976 – 1.06 0.412 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 1.06 0.98 – 1.14 0.152 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 0.979 0.952 – 1.01 0.121 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 0.963 0.903 – 1.03 0.239 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 1.03 0.977 – 1.08 0.301 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 1.01 0.965 – 1.05 0.724 2204 22031 all phecode
375.2 Epiphora Sense Organs 0.978 0.913 – 1.05 0.529 898 8969 all phecode
376 Disorders of the orbit Sense Organs 1.18 0.945 – 1.47 0.143 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.13 1.01 – 1.25 0.0317 361 3618 all phecode
377.1 Optic atrophy Sense Organs 1.1 0.841 – 1.43 0.498 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.13 0.942 – 1.35 0.194 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.977 0.925 – 1.03 0.41 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.972 0.908 – 1.04 0.413 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.955 0.828 – 1.1 0.529 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 0.992 0.877 – 1.12 0.904 275 2755 all phecode
379 Other disorders of eye Sense Organs 1.01 0.981 – 1.05 0.403 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 1.01 0.956 – 1.07 0.696 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.02 0.968 – 1.07 0.513 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 0.965 0.755 – 1.23 0.775 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1 0.905 – 1.11 0.974 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.807 0.688 – 0.947 0.00855 169 1690 all phecode
380 Disorders of external ear Sense Organs 0.995 0.918 – 1.08 0.897 642 6413 all phecode
380.1 Otitis externa Sense Organs 0.962 0.878 – 1.05 0.405 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 1.02 0.916 – 1.14 0.713 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.99 0.947 – 1.04 0.659 2150 21493 all phecode
381.1 Otitis media Sense Organs 0.994 0.946 – 1.04 0.81 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.957 0.891 – 1.03 0.222 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 0.914 0.79 – 1.06 0.229 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.05 0.896 – 1.22 0.561 171 1709 all phecode
381.9 Otorrhea Sense Organs 0.945 0.836 – 1.07 0.36 281 2807 all phecode
382 Otalgia Sense Organs 0.998 0.887 – 1.12 0.969 308 3084 all phecode
383 Otosclerosis Sense Organs 0.98 0.872 – 1.1 0.731 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 0.973 0.918 – 1.03 0.35 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 0.958 0.898 – 1.02 0.188 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.982 0.912 – 1.06 0.634 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 0.981 0.902 – 1.07 0.666 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.908 0.795 – 1.04 0.157 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.968 0.921 – 1.02 0.202 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 0.981 0.901 – 1.07 0.667 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 0.934 0.839 – 1.04 0.208 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 0.985 0.915 – 1.06 0.7 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.985 0.956 – 1.02 0.334 4582 45806 all phecode
388 Other disorders of ear Sense Organs 0.911 0.788 – 1.05 0.205 202 2017 all phecode
389 Hearing loss Sense Organs 1 0.972 – 1.04 0.801 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 1 0.908 – 1.1 0.995 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 0.956 0.867 – 1.05 0.363 450 4497 all phecode
389.4 Tinnitus Sense Organs 0.976 0.89 – 1.07 0.604 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 0.986 0.957 – 1.02 0.344 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 0.988 0.951 – 1.03 0.529 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 0.969 0.914 – 1.03 0.277 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 1 0.942 – 1.07 0.92 1058 10566 all phecode
395 Heart valve disorders Circulatory System 0.986 0.955 – 1.02 0.379 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.991 0.953 – 1.03 0.633 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.961 0.848 – 1.09 0.53 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.03 0.843 – 1.25 0.799 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.909 0.739 – 1.12 0.367 97 970 all phecode
395.6 Heart valve replaced Circulatory System 0.948 0.898 – 1 0.0533 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 0.949 0.889 – 1.01 0.112 1048 10468 all phecode
401 Hypertension Circulatory System 0.996 0.988 – 1 0.344 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 0.996 0.987 – 1 0.303 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.09 1.04 – 1.14 0.000556 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 0.9 0.809 – 1 0.0549 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.14 1.08 – 1.2 1.56e-06 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 1.02 0.862 – 1.21 0.807 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 0.986 0.935 – 1.04 0.611 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 0.991 0.979 – 1 0.125 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.987 0.959 – 1.02 0.367 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 0.99 0.971 – 1.01 0.274 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 0.98 0.964 – 0.996 0.0173 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 0.991 0.976 – 1.01 0.235 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.997 0.921 – 1.08 0.939 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.988 0.971 – 1 0.148 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.976 0.92 – 1.03 0.416 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 0.986 0.939 – 1.03 0.559 1823 18228 all phecode
414.2 ASCVD Circulatory System 0.966 0.766 – 1.22 0.768 72 719 all phecode
415 Pulmonary heart disease Circulatory System 1 0.974 – 1.04 0.793 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1 0.792 – 1.27 0.978 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.962 0.885 – 1.05 0.375 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.03 0.933 – 1.14 0.555 448 4475 all phecode
416 Cardiomegaly Circulatory System 0.98 0.942 – 1.02 0.318 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 0.978 0.966 – 0.99 0.00029 28599 270106 all phecode
418.1 Precordial pain Circulatory System 0.988 0.954 – 1.02 0.494 3551 35541 all phecode
420 Carditis Circulatory System 0.998 0.954 – 1.04 0.919 2106 21053 all phecode
420.1 Myocarditis Circulatory System 0.951 0.789 – 1.15 0.596 127 1267 all phecode
420.2 Pericarditis Circulatory System 1.01 0.955 – 1.07 0.711 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 0.937 0.816 – 1.08 0.361 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 0.998 0.824 – 1.21 0.984 113 1129 all phecode
420.3 Endocarditis Circulatory System 0.968 0.897 – 1.05 0.405 719 7194 all phecode
425 Cardiomyopathy Circulatory System 0.924 0.871 – 0.979 0.00752 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.931 0.878 – 0.988 0.018 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.867 0.728 – 1.03 0.111 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.914 0.78 – 1.07 0.271 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 0.747 0.577 – 0.967 0.0266 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 0.987 0.962 – 1.01 0.29 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1 0.956 – 1.05 0.991 2114 21162 all phecode
426.21 First degree AV block Circulatory System 0.991 0.928 – 1.06 0.785 986 9867 all phecode
426.23 Second degree AV block Circulatory System 0.993 0.901 – 1.09 0.88 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 0.978 0.896 – 1.07 0.614 587 5868 all phecode
426.25 Other heart block Circulatory System 1.17 0.978 – 1.39 0.0868 131 1318 all phecode
426.3 Bundle branch block Circulatory System 0.969 0.934 – 1 0.0806 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 0.986 0.935 – 1.04 0.607 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 0.952 0.906 – 1 0.0501 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.97 0.849 – 1.11 0.653 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 0.992 0.763 – 1.29 0.953 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.96 0.921 – 1 0.0548 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.964 0.923 – 1.01 0.0955 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 0.99 0.977 – 1 0.151 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 0.989 0.953 – 1.03 0.547 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.99 0.949 – 1.03 0.658 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.989 0.924 – 1.06 0.743 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 0.989 0.972 – 1.01 0.215 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.02 0.982 – 1.06 0.322 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.979 0.923 – 1.04 0.488 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.96 0.861 – 1.07 0.465 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 0.975 0.913 – 1.04 0.443 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.01 0.944 – 1.08 0.796 952 9541 all phecode
427.6 Premature beats Circulatory System 0.993 0.908 – 1.09 0.873 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 0.924 0.759 – 1.13 0.432 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 0.984 0.942 – 1.03 0.477 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.93 0.84 – 1.03 0.167 402 4029 all phecode
427.9 Palpitations Circulatory System 0.974 0.941 – 1.01 0.117 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.953 0.927 – 0.98 0.000582 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 0.972 0.929 – 1.02 0.21 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 0.945 0.917 – 0.975 0.000351 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 0.965 0.894 – 1.04 0.365 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 0.913 0.71 – 1.17 0.475 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.972 0.889 – 1.06 0.542 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 0.938 0.812 – 1.08 0.384 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 0.984 0.938 – 1.03 0.501 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.996 0.928 – 1.07 0.917 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1.01 0.935 – 1.08 0.855 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 0.897 0.792 – 1.02 0.0867 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 0.993 0.971 – 1.01 0.512 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.02 0.956 – 1.08 0.625 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 0.994 0.868 – 1.14 0.932 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.01 0.98 – 1.04 0.479 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.997 0.948 – 1.05 0.897 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 0.978 0.941 – 1.02 0.248 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 1 0.957 – 1.05 0.987 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 0.949 0.855 – 1.05 0.325 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.92 0.868 – 0.975 0.00501 1279 12783 all phecode
440 Atherosclerosis Circulatory System 1.01 0.956 – 1.07 0.706 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.01 0.832 – 1.22 0.926 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.996 0.926 – 1.07 0.92 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.11 0.984 – 1.26 0.0872 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.04 0.952 – 1.13 0.415 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.988 0.874 – 1.12 0.843 283 2827 all phecode
442 Other aneurysm Circulatory System 1.02 0.968 – 1.07 0.524 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 1.02 0.969 – 1.08 0.419 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.04 0.972 – 1.11 0.261 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.12 0.916 – 1.36 0.276 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.956 0.817 – 1.12 0.58 169 1696 all phecode
442.4 Arterial dissection Circulatory System 0.941 0.71 – 1.25 0.67 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.09 0.938 – 1.26 0.264 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 1.03 1 – 1.07 0.052 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 1.01 0.945 – 1.07 0.87 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.06 0.955 – 1.18 0.276 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.04 1 – 1.07 0.0471 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.04 1 – 1.09 0.0417 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 1 0.939 – 1.08 0.889 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.04 0.95 – 1.13 0.414 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.02 0.945 – 1.09 0.671 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 1.14 0.975 – 1.33 0.101 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 1.01 0.909 – 1.12 0.867 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 1.04 0.909 – 1.19 0.579 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.03 0.974 – 1.09 0.292 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 1.02 0.948 – 1.09 0.641 868 8712 all phecode
448 Disease of capillaries Circulatory System 0.957 0.813 – 1.13 0.603 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.05 0.97 – 1.13 0.235 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.02 0.987 – 1.05 0.25 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.03 0.993 – 1.06 0.123 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.969 0.888 – 1.06 0.48 564 5645 all phecode
454 Varicose veins Circulatory System 0.973 0.954 – 0.992 0.0058 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 0.969 0.951 – 0.988 0.00153 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.969 0.893 – 1.05 0.452 624 6325 all phecode
455 Hemorrhoids Circulatory System 0.989 0.976 – 1 0.112 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.06 0.914 – 1.23 0.432 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.901 0.726 – 1.12 0.345 97 967 all phecode
458 Hypotension Circulatory System 1.01 0.979 – 1.03 0.675 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 1.07 1.02 – 1.14 0.0122 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 0.969 0.846 – 1.11 0.654 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 1 0.969 – 1.04 0.835 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 0.998 0.982 – 1.01 0.812 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 0.983 0.83 – 1.16 0.84 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 0.997 0.981 – 1.01 0.711 16103 159422 all phecode
464 Acute sinusitis Respiratory 1.05 0.909 – 1.22 0.496 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.987 0.945 – 1.03 0.539 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 1.01 0.943 – 1.09 0.739 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.892 0.763 – 1.04 0.154 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.985 0.956 – 1.02 0.341 4654 46553 all phecode
471 Nasal polyps Respiratory 0.981 0.946 – 1.02 0.287 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.01 0.946 – 1.08 0.732 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1 0.962 – 1.04 0.916 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 1.02 0.835 – 1.24 0.861 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.11 0.976 – 1.25 0.113 264 2647 all phecode
473.4 Voice disturbance Respiratory 1 0.939 – 1.06 0.992 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 1.02 0.973 – 1.07 0.384 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 1.07 0.983 – 1.17 0.115 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.997 0.938 – 1.06 0.923 1122 11199 all phecode
475 Chronic sinusitis Respiratory 0.995 0.956 – 1.04 0.826 2589 25882 all phecode
476 Allergic rhinitis Respiratory 1.03 0.965 – 1.1 0.388 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 0.966 0.927 – 1.01 0.104 2447 24452 all phecode
478 Throat pain Respiratory 0.991 0.89 – 1.1 0.864 377 3789 all phecode
479 Other upper respiratory disease Respiratory 0.965 0.935 – 0.997 0.0309 4074 40737 all phecode
480 Pneumonia Respiratory 0.983 0.963 – 1 0.0987 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 0.984 0.96 – 1.01 0.223 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 0.993 0.967 – 1.02 0.618 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 0.927 0.754 – 1.14 0.477 93 929 all phecode
480.2 Viral pneumonia Respiratory 0.927 0.728 – 1.18 0.536 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.05 0.859 – 1.29 0.628 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.96 0.893 – 1.03 0.275 794 7951 all phecode
481 Influenza Respiratory 0.996 0.887 – 1.12 0.944 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.92 0.792 – 1.07 0.274 193 1930 all phecode
495 Asthma Respiratory 0.982 0.969 – 0.995 0.00591 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 0.885 0.777 – 1.01 0.0676 250 2510 all phecode
496 Chronic airway obstruction Respiratory 0.97 0.95 – 0.99 0.0031 10424 101546 all phecode
496.1 Emphysema Respiratory 0.993 0.945 – 1.04 0.784 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 0.979 0.943 – 1.02 0.277 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 0.968 0.931 – 1.01 0.111 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 0.95 0.905 – 0.996 0.0341 1885 18859 all phecode
497 Bronchitis Respiratory 1.02 0.939 – 1.11 0.657 626 6267 all phecode
500 Lung disease due to external agents Respiratory 1.07 0.962 – 1.18 0.224 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.979 0.779 – 1.23 0.854 79 784 all phecode
500.2 Pneumoconiosis Respiratory 1.1 0.959 – 1.25 0.178 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 0.988 0.912 – 1.07 0.768 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.05 0.985 – 1.13 0.127 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 0.908 0.829 – 0.995 0.0384 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.09 0.974 – 1.22 0.136 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.05 0.814 – 1.36 0.695 61 610 all phecode
506 Empyema and pneumothorax Respiratory 1.01 0.954 – 1.08 0.647 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 0.979 0.955 – 1 0.113 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.956 0.913 – 1 0.0538 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.976 0.937 – 1.02 0.237 2599 26031 all phecode
509.1 Respiratory failure Respiratory 0.972 0.929 – 1.02 0.217 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 0.98 0.933 – 1.03 0.407 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 0.969 0.816 – 1.15 0.72 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.991 0.892 – 1.1 0.873 386 3863 all phecode
510 Other diseases of lung Respiratory 1.01 0.939 – 1.09 0.757 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 0.994 0.972 – 1.02 0.558 9031 90349 all phecode
512.1 Wheezing Respiratory 1.05 0.911 – 1.2 0.515 220 2196 all phecode
512.2 Painful respiration Respiratory 0.966 0.841 – 1.11 0.626 207 2075 all phecode
512.7 Shortness of breath Respiratory 0.992 0.965 – 1.02 0.553 5842 58498 all phecode
512.8 Cough Respiratory 1 0.963 – 1.04 0.941 2866 28642 all phecode
512.9 Other dyspnea Respiratory 0.944 0.882 – 1.01 0.0996 914 9124 all phecode
513 Respiratory abnormalities Respiratory 0.981 0.903 – 1.07 0.654 611 6112 all phecode
513.3 Hypoventilation Respiratory 1.04 0.836 – 1.3 0.712 83 830 all phecode
513.4 Hyperventilation Respiratory 0.94 0.83 – 1.07 0.333 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 0.944 0.801 – 1.11 0.498 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 1.01 0.965 – 1.05 0.764 2465 24673 all phecode
516 Abnormal sputum Respiratory 0.955 0.914 – 0.999 0.044 2132 21335 all phecode
516.1 Hemoptysis Respiratory 0.962 0.92 – 1.01 0.0949 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.984 0.963 – 1.01 0.143 9366 93681 all phecode
519.2 Respiratory complications Respiratory 0.995 0.888 – 1.11 0.928 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.986 0.965 – 1.01 0.215 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.996 0.885 – 1.12 0.953 303 3049 all phecode
520 Disorders of tooth development Digestive 1.01 0.97 – 1.06 0.524 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.905 0.693 – 1.18 0.46 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 1.02 0.977 – 1.06 0.372 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 1.02 0.979 – 1.06 0.4 3016 30245 all phecode
521.1 Dental caries Digestive 1.02 0.978 – 1.05 0.42 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 0.957 0.911 – 1 0.0782 1774 17750 all phecode
522.5 Periapical abscess Digestive 0.957 0.901 – 1.02 0.159 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 1.03 0.977 – 1.08 0.286 1681 16812 all phecode
523.1 Gingivitis Digestive 0.941 0.777 – 1.14 0.538 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.04 0.979 – 1.11 0.203 1165 11650 all phecode
523.31 Acute periodontitis Digestive 1.05 0.97 – 1.14 0.229 666 6667 all phecode
523.32 Chronic periodontitis Digestive 1.07 0.985 – 1.17 0.107 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.02 0.917 – 1.14 0.665 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.02 0.904 – 1.14 0.8 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.975 0.937 – 1.01 0.208 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.835 0.666 – 1.05 0.118 72 720 all phecode
526 Diseases of the jaws Digestive 0.961 0.898 – 1.03 0.251 928 9279 all phecode
526.1 Cysts of the jaws Digestive 0.938 0.837 – 1.05 0.271 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.965 0.735 – 1.27 0.797 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 0.981 0.864 – 1.11 0.763 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.987 0.868 – 1.12 0.841 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.985 0.814 – 1.19 0.879 110 1098 all phecode
526.9 Jaw disease NOS Digestive 0.962 0.839 – 1.1 0.579 233 2329 all phecode
527 Diseases of the salivary glands Digestive 0.969 0.895 – 1.05 0.433 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 0.951 0.753 – 1.2 0.677 84 838 all phecode
527.2 Sialoadenitis Digestive 0.965 0.866 – 1.07 0.517 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 0.842 0.65 – 1.09 0.194 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 0.987 0.822 – 1.19 0.89 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.985 0.953 – 1.02 0.374 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 0.973 0.884 – 1.07 0.571 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.963 0.867 – 1.07 0.478 389 3884 all phecode
528.12 Oral aphthae Digestive 0.913 0.729 – 1.14 0.431 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.96 0.823 – 1.12 0.6 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 1.03 0.857 – 1.23 0.776 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 1.11 0.915 – 1.36 0.281 94 940 all phecode
528.5 Diseases of lips Digestive 0.929 0.859 – 1 0.0632 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.03 0.916 – 1.15 0.648 308 3079 all phecode
528.7 Sialolithiasis Digestive 0.971 0.865 – 1.09 0.62 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 1.03 0.968 – 1.09 0.393 1232 12312 all phecode
529.1 Glossitis Digestive 1 0.891 – 1.12 0.991 299 2986 all phecode
530 Diseases of esophagus Digestive 0.984 0.973 – 0.995 0.00479 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.986 0.974 – 0.997 0.0159 31253 272429 all phecode
530.11 GERD Digestive 0.987 0.973 – 1 0.0576 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 0.973 0.946 – 1 0.0606 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 0.992 0.972 – 1.01 0.408 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.968 0.921 – 1.02 0.211 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1 0.954 – 1.05 0.977 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 1.04 0.956 – 1.13 0.368 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.972 0.824 – 1.15 0.732 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.901 0.805 – 1.01 0.0682 341 3416 all phecode
530.9 Heartburn Digestive 1.03 0.985 – 1.08 0.196 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.957 0.934 – 0.98 0.000365 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.97 0.894 – 1.05 0.457 637 6374 all phecode
531.2 Gastric ulcer Digestive 0.952 0.922 – 0.983 0.00252 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 0.938 0.903 – 0.974 0.000795 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 0.966 0.876 – 1.07 0.489 427 4268 all phecode
532 Dysphagia Digestive 0.984 0.959 – 1.01 0.209 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 0.991 0.979 – 1 0.145 28078 261548 all phecode
535.1 Acute gastritis Digestive 0.989 0.931 – 1.05 0.722 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 0.997 0.896 – 1.11 0.958 370 3687 all phecode
535.6 Duodenitis Digestive 0.995 0.971 – 1.02 0.667 7592 75928 all phecode
535.8 Other specified gastritis Digestive 0.988 0.966 – 1.01 0.316 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.995 0.826 – 1.2 0.959 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.963 0.848 – 1.09 0.567 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 0.983 0.949 – 1.02 0.348 3391 33907 all phecode
540 Appendiceal conditions Digestive 1.01 0.971 – 1.05 0.67 3088 30890 all phecode
540.1 Appendicitis Digestive 1.01 0.973 – 1.05 0.586 2895 28963 all phecode
540.11 Acute appendicitis Digestive 1.03 0.992 – 1.08 0.12 2601 26019 all phecode
550 Abdominal hernia Digestive 0.979 0.969 – 0.988 2.35e-05 45429 282640 all phecode
550.1 Inguinal hernia Digestive 0.965 0.949 – 0.981 2.74e-05 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 0.983 0.97 – 0.995 0.00743 26494 238953 all phecode
550.3 Femoral hernia Digestive 0.943 0.869 – 1.02 0.155 651 6504 all phecode
550.4 Umbilical hernia Digestive 0.984 0.951 – 1.02 0.352 3705 37072 all phecode
550.5 Ventral hernia Digestive 0.993 0.958 – 1.03 0.69 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 0.946 0.917 – 0.976 0.000427 4444 44442 all phecode
555.1 Regional enteritis Digestive 0.936 0.891 – 0.984 0.00892 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 0.967 0.932 – 1 0.0722 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 0.948 0.868 – 1.04 0.237 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 0.945 0.887 – 1.01 0.0802 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 0.911 0.841 – 0.986 0.0212 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.07 0.954 – 1.21 0.241 299 2987 all phecode
557.1 Celiac disease Digestive 1.22 1.16 – 1.28 7.93e-16 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 0.994 0.978 – 1.01 0.494 15492 155105 all phecode
559 Ileostomy status Digestive 1.02 0.968 – 1.07 0.474 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 0.987 0.955 – 1.02 0.449 3936 39337 all phecode
560.1 Paralytic ileus Digestive 1.04 0.949 – 1.14 0.406 523 5231 all phecode
560.2 Impaction of intestine Digestive 0.922 0.814 – 1.04 0.203 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.988 0.92 – 1.06 0.741 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 0.99 0.955 – 1.03 0.578 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 0.996 0.98 – 1.01 0.616 15772 157686 all phecode
561.1 Diarrhea Digestive 1.07 0.974 – 1.18 0.157 466 4653 all phecode
561.2 Flatulence Digestive 0.981 0.934 – 1.03 0.462 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 0.984 0.971 – 0.996 0.0126 26714 211692 all phecode
562.1 Diverticulosis Digestive 0.984 0.971 – 0.996 0.0122 26672 211642 all phecode
563 Constipation Digestive 0.992 0.972 – 1.01 0.424 10314 103140 all phecode
564 Functional digestive disorders Digestive 0.978 0.965 – 0.992 0.0024 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 0.977 0.951 – 1 0.107 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 0.999 0.95 – 1.05 0.981 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 0.972 0.955 – 0.988 0.00076 15186 151648 all phecode
565 Anal and rectal conditions Digestive 0.988 0.971 – 1.01 0.166 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 0.982 0.959 – 1.01 0.14 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1 0.935 – 1.07 0.999 929 9293 all phecode
568 Other disorders of peritoneum Digestive 0.96 0.926 – 0.995 0.0258 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.965 0.93 – 1 0.0615 3101 30987 all phecode
569 Other disorders of intestine Digestive 0.99 0.959 – 1.02 0.526 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.05 0.892 – 1.25 0.535 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 0.964 0.878 – 1.06 0.442 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 0.978 0.941 – 1.02 0.245 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 0.994 0.945 – 1.05 0.815 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.12 0.93 – 1.36 0.226 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 0.995 0.877 – 1.13 0.944 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.962 0.901 – 1.03 0.252 976 9804 all phecode
571.81 Portal hypertension Digestive 0.913 0.835 – 0.999 0.048 528 5285 all phecode
572 Ascites (non malignant) Digestive 0.968 0.918 – 1.02 0.221 1544 15454 all phecode
573 Other disorders of liver Digestive 0.97 0.92 – 1.02 0.265 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 0.936 0.762 – 1.15 0.528 96 960 all phecode
573.3 Hepatomegaly Digestive 0.955 0.847 – 1.08 0.454 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 1.01 0.943 – 1.08 0.773 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 1.01 0.979 – 1.05 0.421 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.06 0.925 – 1.22 0.398 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 0.979 0.963 – 0.995 0.0106 15607 156123 all phecode
574.1 Cholelithiasis Digestive 0.98 0.962 – 0.997 0.0228 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.991 0.94 – 1.04 0.741 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.985 0.957 – 1.01 0.277 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 0.974 0.935 – 1.01 0.194 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.949 0.913 – 0.987 0.0096 2748 27523 all phecode
575 Other biliary tract disease Digestive 0.986 0.954 – 1.02 0.4 3867 38724 all phecode
575.1 Cholangitis Digestive 1.01 0.919 – 1.11 0.852 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 0.993 0.922 – 1.07 0.863 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 1.03 0.938 – 1.13 0.521 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 0.99 0.937 – 1.05 0.709 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 0.954 0.895 – 1.02 0.157 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.915 0.821 – 1.02 0.109 348 3488 all phecode
577 Diseases of pancreas Digestive 1.02 0.977 – 1.06 0.406 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 1.04 0.992 – 1.09 0.107 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 1 0.914 – 1.09 0.993 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.04 0.936 – 1.16 0.449 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 0.981 0.967 – 0.995 0.00833 20626 206278 all phecode
578.1 Hematemesis Digestive 0.999 0.953 – 1.05 0.95 1958 19564 all phecode
578.2 Blood in stool Digestive 0.963 0.925 – 1 0.0679 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 0.981 0.963 – 0.999 0.0347 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.977 0.949 – 1 0.106 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.01 0.961 – 1.07 0.621 1548 15498 all phecode
579.2 Splenomegaly Digestive 1.02 0.919 – 1.13 0.741 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.948 0.901 – 0.998 0.0397 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.17 1.11 – 1.23 6.81e-09 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 1.19 1.11 – 1.26 1.64e-07 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.02 0.807 – 1.29 0.876 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.06 0.887 – 1.27 0.515 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.22 1.14 – 1.31 2.7e-08 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.06 0.961 – 1.16 0.252 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.13 0.995 – 1.29 0.0603 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.12 0.983 – 1.28 0.0887 253 2529 all phecode
585 Renal failure Genitourinary 1.08 1.06 – 1.11 5.01e-10 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 1.04 1.01 – 1.07 0.0179 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 1.1 1.04 – 1.16 0.000683 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.16 1.11 – 1.21 9.5e-13 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 1 0.912 – 1.1 0.989 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 0.993 0.958 – 1.03 0.687 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.95 0.821 – 1.1 0.498 208 2089 all phecode
586.11 Small kidney Genitourinary 0.997 0.852 – 1.17 0.974 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 0.993 0.937 – 1.05 0.818 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.909 0.729 – 1.14 0.402 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.928 0.867 – 0.994 0.0321 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 1.07 0.959 – 1.18 0.237 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 0.96 0.783 – 1.18 0.69 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.02 0.847 – 1.23 0.833 116 1158 all phecode
590 Pyelonephritis Genitourinary 1 0.947 – 1.06 0.928 1328 13285 all phecode
591 Urinary tract infection Genitourinary 0.986 0.968 – 1 0.131 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 0.984 0.947 – 1.02 0.397 2966 29661 all phecode
592.1 Cystitis Genitourinary 0.979 0.942 – 1.02 0.276 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 1.04 0.869 – 1.24 0.683 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 1.01 0.943 – 1.08 0.765 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 1.11 0.971 – 1.26 0.126 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1 0.855 – 1.18 0.958 165 1662 all phecode
593 Hematuria Genitourinary 0.959 0.943 – 0.974 3.72e-07 16068 160204 all phecode
594 Urinary calculus Genitourinary 0.888 0.865 – 0.911 3.62e-19 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 0.848 0.817 – 0.88 2.16e-18 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 0.936 0.869 – 1.01 0.0818 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 0.882 0.845 – 0.92 7.33e-09 2401 24024 all phecode
594.8 Renal colic Genitourinary 0.889 0.85 – 0.93 3.76e-07 2050 20500 all phecode
595 Hydronephrosis Genitourinary 0.957 0.914 – 1 0.0677 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 0.985 0.965 – 1.01 0.168 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 0.962 0.918 – 1.01 0.0992 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 0.972 0.924 – 1.02 0.278 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.965 0.934 – 0.997 0.0348 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.963 0.93 – 0.998 0.041 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 0.841 0.663 – 1.07 0.153 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 0.978 0.945 – 1.01 0.215 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.967 0.859 – 1.09 0.581 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.973 0.958 – 0.988 0.000458 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 0.932 0.794 – 1.09 0.39 166 1670 all phecode
599.2 Retention of urine Genitourinary 0.978 0.954 – 1 0.0855 6718 67168 all phecode
599.3 Dysuria Genitourinary 0.98 0.923 – 1.04 0.512 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 0.979 0.958 – 1 0.0618 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 0.948 0.918 – 0.979 0.00131 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 1.01 0.822 – 1.23 0.947 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 0.79 0.611 – 1.02 0.0717 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 0.982 0.936 – 1.03 0.437 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 0.983 0.963 – 1 0.0857 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.958 0.916 – 1 0.0645 2081 20818 all phecode
601.1 Prostatitis Genitourinary 0.949 0.901 – 1 0.0487 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 0.897 0.783 – 1.03 0.117 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 0.959 0.896 – 1.03 0.235 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 0.839 0.64 – 1.1 0.204 59 588 all phecode
601.4 Balanoposthitis Genitourinary 0.955 0.846 – 1.08 0.454 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.04 0.925 – 1.17 0.511 303 3019 all phecode
602 Other disorders of prostate Genitourinary 0.959 0.907 – 1.01 0.148 1341 13408 all phecode
603 Other disorders of testis Genitourinary 1.01 0.968 – 1.06 0.588 2150 21512 all phecode
603.1 Hydrocele Genitourinary 1.06 1 – 1.12 0.0507 1339 13402 all phecode
604 Disorders of penis Genitourinary 1.01 0.979 – 1.05 0.42 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.02 0.985 – 1.07 0.235 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 0.967 0.856 – 1.09 0.586 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 0.988 0.95 – 1.03 0.556 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.9 0.78 – 1.04 0.152 214 2138 all phecode
609.1 Infertility, male Genitourinary 0.819 0.622 – 1.08 0.156 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.883 0.752 – 1.04 0.13 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 1.01 0.969 – 1.05 0.635 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 1.02 0.955 – 1.09 0.534 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.05 0.932 – 1.17 0.439 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 1.01 0.901 – 1.14 0.837 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 1.01 0.951 – 1.06 0.857 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.987 0.914 – 1.07 0.732 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.996 0.945 – 1.05 0.872 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 0.84 0.639 – 1.1 0.21 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 1.01 0.954 – 1.06 0.818 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.997 0.93 – 1.07 0.932 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.991 0.923 – 1.07 0.815 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 1.06 0.825 – 1.35 0.666 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 0.98 0.932 – 1.03 0.439 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.02 0.94 – 1.1 0.701 720 7210 all phecode
613.5 Mastodynia Genitourinary 1.11 0.879 – 1.41 0.377 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.919 0.85 – 0.993 0.0329 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 0.966 0.863 – 1.08 0.551 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 1.03 0.894 – 1.19 0.672 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.965 0.939 – 0.991 0.0094 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.938 0.9 – 0.977 0.00209 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.956 0.89 – 1.03 0.219 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.11 0.858 – 1.44 0.426 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.948 0.858 – 1.05 0.291 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.01 0.901 – 1.12 0.918 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.06 0.933 – 1.19 0.393 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.984 0.945 – 1.02 0.441 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.98 0.926 – 1.04 0.494 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.03 0.931 – 1.13 0.599 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.943 0.876 – 1.01 0.116 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.957 0.843 – 1.08 0.489 274 2737 all phecode
615 Endometriosis Genitourinary 0.978 0.947 – 1.01 0.181 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 0.936 0.831 – 1.05 0.278 304 3037 all phecode
618 Genital prolapse Genitourinary 0.953 0.935 – 0.972 9.01e-07 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 0.959 0.936 – 0.982 0.000662 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.947 0.92 – 0.973 0.000125 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.04 0.953 – 1.14 0.352 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.936 0.864 – 1.01 0.0998 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.981 0.96 – 1 0.0931 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.959 0.888 – 1.04 0.285 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 0.977 0.943 – 1.01 0.2 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1 0.962 – 1.04 0.994 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.954 0.908 – 1 0.0596 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.01 0.957 – 1.07 0.683 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 0.947 0.751 – 1.19 0.645 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 0.998 0.938 – 1.06 0.955 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 0.995 0.975 – 1.02 0.648 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 1.01 0.984 – 1.03 0.574 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.998 0.964 – 1.03 0.931 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 0.963 0.908 – 1.02 0.199 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 1.02 0.945 – 1.09 0.661 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 1.05 0.918 – 1.19 0.496 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.978 0.887 – 1.08 0.654 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 0.981 0.955 – 1.01 0.168 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.04 1 – 1.08 0.0523 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 1.03 0.969 – 1.09 0.354 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.998 0.982 – 1.01 0.828 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.998 0.98 – 1.02 0.792 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 1.16 0.955 – 1.41 0.135 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 0.989 0.968 – 1.01 0.286 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 1 0.955 – 1.05 0.999 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.997 0.965 – 1.03 0.876 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 1.04 0.99 – 1.09 0.118 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.984 0.836 – 1.16 0.851 159 1587 all phecode
626.8 Infertility, female Genitourinary 0.964 0.912 – 1.02 0.194 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.983 0.964 – 1 0.106 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 0.991 0.97 – 1.01 0.433 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 0.937 0.807 – 1.09 0.387 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.972 0.914 – 1.03 0.371 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.94 0.835 – 1.06 0.309 310 3097 all phecode
628 Ovarian cyst Genitourinary 0.973 0.944 – 1 0.0673 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.988 0.959 – 1.02 0.416 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.02 0.96 – 1.08 0.516 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.04 0.925 – 1.16 0.544 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.984 0.939 – 1.03 0.485 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.943 0.88 – 1.01 0.0961 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.01 0.955 – 1.07 0.715 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.01 0.971 – 1.06 0.538 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 1.02 0.94 – 1.11 0.617 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.01 0.946 – 1.07 0.841 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 1.03 0.805 – 1.32 0.82 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.945 0.889 – 1 0.0699 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.882 0.784 – 0.993 0.0373 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.879 0.761 – 1.01 0.0771 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.941 0.795 – 1.11 0.48 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.973 0.918 – 1.03 0.355 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.02 0.978 – 1.07 0.341 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.877 0.685 – 1.12 0.3 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.99 0.875 – 1.12 0.874 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.99 0.814 – 1.2 0.921 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.08 0.932 – 1.24 0.321 193 1922 all phecode
650 Normal delivery Pregnancy Complications 1.01 0.96 – 1.05 0.794 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 0.988 0.886 – 1.1 0.832 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1.01 0.962 – 1.06 0.656 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.949 0.898 – 1 0.0629 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 0.988 0.777 – 1.26 0.92 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.01 0.974 – 1.04 0.746 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.932 0.77 – 1.13 0.472 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 1 0.961 – 1.05 0.856 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.972 0.89 – 1.06 0.527 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 1.02 0.986 – 1.05 0.295 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.973 0.934 – 1.01 0.19 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.02 0.871 – 1.2 0.798 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.951 0.84 – 1.08 0.424 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.875 0.678 – 1.13 0.302 63 624 all phecode
679 Complications of in utero procedures Dermatologic 1.15 0.869 – 1.51 0.333 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.01 0.982 – 1.03 0.625 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.04 0.951 – 1.13 0.416 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.929 0.848 – 1.02 0.112 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.01 0.979 – 1.03 0.646 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.01 0.978 – 1.03 0.689 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.01 0.98 – 1.04 0.565 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 0.932 0.857 – 1.01 0.097 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.02 0.962 – 1.08 0.533 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 0.924 0.885 – 0.964 0.000312 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 0.904 0.83 – 0.985 0.0214 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 0.972 0.873 – 1.08 0.603 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 0.97 0.887 – 1.06 0.493 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.04 0.992 – 1.08 0.112 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.08 0.96 – 1.22 0.192 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 0.888 0.724 – 1.09 0.259 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 0.994 0.956 – 1.03 0.743 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.962 0.937 – 0.989 0.00554 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.889 0.697 – 1.13 0.343 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.816 0.621 – 1.07 0.144 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 1 0.831 – 1.21 0.964 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.953 0.893 – 1.02 0.152 986 9854 all phecode
694.1 Vitiligo Dermatologic 1 0.778 – 1.3 0.972 60 599 all phecode
694.2 Other dyschromia Dermatologic 0.964 0.896 – 1.04 0.326 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 0.961 0.796 – 1.16 0.677 117 1170 all phecode
695 Erythematous conditions Dermatologic 0.954 0.915 – 0.996 0.031 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 1.01 0.835 – 1.23 0.888 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 0.845 0.709 – 1.01 0.059 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 0.894 0.681 – 1.17 0.416 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.737 0.579 – 0.937 0.0126 73 727 all phecode
695.3 Rosacea Dermatologic 0.832 0.738 – 0.939 0.00285 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 0.907 0.82 – 1 0.0597 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.9 0.752 – 1.08 0.248 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 0.889 0.795 – 0.994 0.0383 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 1.05 0.976 – 1.13 0.182 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 0.972 0.854 – 1.11 0.666 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 1.12 0.888 – 1.41 0.338 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 0.966 0.879 – 1.06 0.468 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 1 0.961 – 1.05 0.859 2252 22509 all phecode
696.4 Psoriasis Dermatologic 1 0.957 – 1.05 0.992 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.01 0.957 – 1.06 0.814 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 0.97 0.898 – 1.05 0.438 706 7052 all phecode
697 Sarcoidosis Dermatologic 1.09 0.993 – 1.19 0.07 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 0.939 0.873 – 1.01 0.0887 782 7814 all phecode
700 Corns and callosities Dermatologic 0.94 0.832 – 1.06 0.324 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.982 0.953 – 1.01 0.24 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 0.962 0.774 – 1.2 0.724 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.96 0.92 – 1 0.0634 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 0.996 0.783 – 1.27 0.975 61 610 all phecode
701.4 Keloid scar Dermatologic 1.01 0.883 – 1.16 0.881 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 1 0.909 – 1.11 0.959 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 0.963 0.791 – 1.17 0.706 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.997 0.969 – 1.02 0.817 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 0.999 0.96 – 1.04 0.974 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 0.994 0.958 – 1.03 0.759 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 1.01 0.904 – 1.12 0.894 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 0.993 0.93 – 1.06 0.833 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 0.962 0.935 – 0.989 0.00673 5267 52727 all phecode
704.1 Alopecia Dermatologic 0.884 0.741 – 1.05 0.17 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.997 0.785 – 1.27 0.983 76 759 all phecode
705 Disorders of sweat glands Dermatologic 0.903 0.788 – 1.03 0.141 228 2287 all phecode
705.3 Hidradenitis Dermatologic 0.907 0.78 – 1.06 0.209 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 0.907 0.834 – 0.987 0.0239 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 0.974 0.952 – 0.996 0.0206 8317 83195 all phecode
706.1 Acne Dermatologic 0.777 0.614 – 0.984 0.0361 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 0.975 0.953 – 0.996 0.0212 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 1.03 0.987 – 1.08 0.153 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 1 0.936 – 1.07 0.959 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 1.03 0.998 – 1.07 0.0653 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 0.993 0.907 – 1.09 0.882 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 1.03 0.883 – 1.2 0.7 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.936 0.729 – 1.2 0.605 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.03 0.991 – 1.07 0.127 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.987 0.907 – 1.07 0.76 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 0.984 0.902 – 1.07 0.727 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.921 0.795 – 1.07 0.274 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.01 0.913 – 1.12 0.828 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 0.983 0.889 – 1.09 0.73 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 0.997 0.89 – 1.12 0.959 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.12 0.895 – 1.41 0.316 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.03 0.868 – 1.22 0.747 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 0.979 0.758 – 1.26 0.871 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.973 0.944 – 1 0.0716 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.974 0.944 – 1.01 0.101 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.988 0.94 – 1.04 0.642 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.961 0.8 – 1.15 0.67 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.961 0.885 – 1.04 0.338 618 6177 all phecode
716 Other arthropathies Musculoskeletal 0.989 0.978 – 1 0.048 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.957 0.925 – 0.991 0.0143 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.981 0.965 – 0.997 0.0234 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 0.991 0.98 – 1 0.102 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.985 0.926 – 1.05 0.621 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 1.03 0.997 – 1.07 0.0714 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 0.975 0.952 – 0.998 0.031 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.979 0.951 – 1.01 0.161 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1 0.866 – 1.17 0.95 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 0.987 0.885 – 1.1 0.816 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 1 0.98 – 1.02 0.897 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.04 0.947 – 1.13 0.443 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.06 1.02 – 1.11 0.00149 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.19 0.931 – 1.53 0.164 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1 0.971 – 1.03 0.889 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 0.999 0.911 – 1.09 0.974 517 5173 all phecode
723.1 Torticollis Musculoskeletal 0.972 0.799 – 1.18 0.777 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 0.989 0.946 – 1.04 0.643 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 0.992 0.896 – 1.1 0.88 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 0.977 0.883 – 1.08 0.654 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.03 0.796 – 1.33 0.819 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 0.985 0.936 – 1.04 0.573 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.01 0.992 – 1.03 0.295 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 1.01 0.988 – 1.03 0.395 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 1 0.893 – 1.12 0.995 334 3336 all phecode
726.3 Bursitis Musculoskeletal 1.03 0.963 – 1.11 0.365 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.987 0.964 – 1.01 0.296 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.989 0.95 – 1.03 0.566 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 1.19 0.968 – 1.47 0.0979 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.989 0.953 – 1.03 0.538 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 1.01 0.931 – 1.11 0.745 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.04 0.931 – 1.17 0.466 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.9 0.756 – 1.07 0.234 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.04 1 – 1.07 0.0444 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.02 0.925 – 1.14 0.637 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 1.03 1 – 1.07 0.053 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.03 0.995 – 1.07 0.0953 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.01 0.98 – 1.03 0.651 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.923 0.864 – 0.985 0.0166 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 0.779 0.635 – 0.956 0.0167 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.882 0.778 – 0.999 0.0483 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.847 0.745 – 0.964 0.0117 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 0.965 0.878 – 1.06 0.464 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.918 0.796 – 1.06 0.239 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.847 0.641 – 1.12 0.243 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.949 0.904 – 0.996 0.0344 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 0.985 0.876 – 1.11 0.807 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.926 0.847 – 1.01 0.0916 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 1.19 0.989 – 1.43 0.0646 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.04 0.977 – 1.1 0.233 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 1.11 0.917 – 1.34 0.285 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 0.987 0.967 – 1.01 0.237 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 0.941 0.811 – 1.09 0.421 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 0.973 0.945 – 1 0.0622 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.993 0.947 – 1.04 0.766 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 0.973 0.924 – 1.03 0.313 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.99 0.966 – 1.02 0.451 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.983 0.934 – 1.03 0.509 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.01 0.889 – 1.15 0.866 248 2476 all phecode
737 Curvature of spine Musculoskeletal 0.991 0.931 – 1.05 0.766 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.988 0.926 – 1.05 0.704 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.998 0.952 – 1.05 0.942 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.02 0.967 – 1.08 0.473 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 1 0.912 – 1.1 0.947 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 0.985 0.972 – 0.997 0.0157 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.988 0.973 – 1 0.13 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.995 0.974 – 1.02 0.66 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.99 0.888 – 1.1 0.861 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.963 0.885 – 1.05 0.387 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.98 0.962 – 0.998 0.0313 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.997 0.963 – 1.03 0.855 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 0.956 0.78 – 1.17 0.668 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 1.02 0.943 – 1.11 0.573 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 0.936 0.788 – 1.11 0.446 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 0.992 0.939 – 1.05 0.771 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 1.12 0.921 – 1.37 0.251 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 1.19 0.899 – 1.57 0.228 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.01 0.969 – 1.05 0.697 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 1 0.895 – 1.12 0.969 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.14 0.917 – 1.42 0.239 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 0.919 0.838 – 1.01 0.0721 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 1.03 0.985 – 1.08 0.183 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.955 0.933 – 0.978 0.000136 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 0.949 0.925 – 0.974 6.54e-05 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.946 0.92 – 0.973 8.82e-05 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 0.908 0.831 – 0.993 0.034 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 0.926 0.846 – 1.01 0.094 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.01 0.94 – 1.08 0.792 815 8144 all phecode
745 Pain in joint Musculoskeletal 0.974 0.952 – 0.997 0.0264 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.01 0.974 – 1.05 0.528 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.01 0.971 – 1.05 0.603 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1.1 1.01 – 1.2 0.0323 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.04 0.911 – 1.2 0.539 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.983 0.936 – 1.03 0.476 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.05 0.892 – 1.23 0.576 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.1 0.824 – 1.47 0.52 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.938 0.833 – 1.06 0.289 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 1.1 1.02 – 1.19 0.0188 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.09 0.976 – 1.22 0.123 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.02 0.879 – 1.18 0.816 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.09 0.974 – 1.21 0.136 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.13 0.991 – 1.3 0.0679 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.01 0.837 – 1.22 0.92 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.01 0.959 – 1.07 0.691 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.01 0.935 – 1.09 0.801 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.03 0.942 – 1.14 0.477 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.07 0.931 – 1.23 0.339 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.997 0.929 – 1.07 0.941 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 1.04 0.938 – 1.15 0.473 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.949 0.847 – 1.06 0.359 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.08 0.963 – 1.2 0.193 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 1.04 0.916 – 1.18 0.543 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 0.989 0.861 – 1.14 0.876 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.25 0.991 – 1.59 0.0592 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.966 0.804 – 1.16 0.71 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.04 0.814 – 1.32 0.768 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.884 0.72 – 1.09 0.24 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.938 0.85 – 1.04 0.209 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.933 0.81 – 1.07 0.333 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.909 0.775 – 1.07 0.238 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.982 0.809 – 1.19 0.858 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.972 0.894 – 1.06 0.503 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.851 0.683 – 1.06 0.152 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.992 0.9 – 1.09 0.872 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.03 0.864 – 1.22 0.771 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.958 0.737 – 1.24 0.747 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.01 0.876 – 1.16 0.926 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.978 0.795 – 1.2 0.83 96 959 all phecode
760 Back pain Symptoms 0.991 0.972 – 1.01 0.373 11126 111353 all phecode
761 Cervicalgia Symptoms 0.954 0.909 – 1 0.0587 1791 17901 all phecode
764 Sciatica Symptoms 0.986 0.945 – 1.03 0.506 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.04 0.974 – 1.1 0.261 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 1.02 0.937 – 1.1 0.696 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.977 0.911 – 1.05 0.505 870 8687 all phecode
771.1 Swelling of limb Symptoms 1.02 0.987 – 1.05 0.26 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 0.972 0.897 – 1.05 0.481 659 6581 all phecode
773 Pain in limb Symptoms 1.03 0.999 – 1.05 0.0564 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 1.01 0.866 – 1.18 0.874 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.977 0.932 – 1.02 0.338 1870 18715 all phecode
782.3 Edema Symptoms 0.941 0.895 – 0.99 0.0191 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 0.839 0.72 – 0.977 0.0238 175 1748 all phecode
783 Fever of unknown origin Symptoms 1.01 0.979 – 1.05 0.477 3911 39105 all phecode
785 Abdominal pain Symptoms 0.99 0.98 – 1 0.0741 40080 301686 all phecode
788 Syncope and collapse Symptoms 1.01 0.993 – 1.04 0.199 9069 90813 all phecode
789 Nausea and vomiting Symptoms 0.998 0.979 – 1.02 0.855 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.09 0.918 – 1.29 0.328 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 1.15 0.908 – 1.45 0.25 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 0.996 0.971 – 1.02 0.788 6357 63635 all phecode
791 Gangrene Symptoms 1 0.916 – 1.09 0.996 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.795 0.649 – 0.974 0.0272 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.981 0.822 – 1.17 0.831 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 0.983 0.901 – 1.07 0.697 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.16 0.961 – 1.4 0.122 120 1198 all phecode
797 Shock Symptoms 1.03 0.876 – 1.22 0.703 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 1.16 0.947 – 1.41 0.154 102 1020 all phecode
798 Malaise and fatigue Symptoms 1.01 0.978 – 1.05 0.474 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 1.01 0.928 – 1.1 0.796 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 0.974 0.95 – 0.998 0.0349 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.971 0.925 – 1.02 0.238 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.03 0.88 – 1.2 0.739 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.936 0.895 – 0.978 0.00345 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 1.07 0.992 – 1.15 0.0806 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.968 0.926 – 1.01 0.143 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 0.962 0.917 – 1.01 0.114 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 1.04 0.963 – 1.12 0.32 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 1 0.98 – 1.03 0.816 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 0.997 0.948 – 1.05 0.896 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.01 0.984 – 1.04 0.41 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.983 0.932 – 1.04 0.534 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.982 0.947 – 1.02 0.31 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.02 0.961 – 1.07 0.583 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 0.978 0.908 – 1.05 0.566 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.01 0.953 – 1.07 0.758 1300 12998 all phecode
817 Concussion Injuries & Poisonings 0.979 0.859 – 1.12 0.751 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.963 0.879 – 1.05 0.413 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.959 0.924 – 0.996 0.0315 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 0.953 0.906 – 1 0.0642 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 0.99 0.946 – 1.04 0.652 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 0.991 0.975 – 1.01 0.296 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 0.988 0.903 – 1.08 0.792 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 0.992 0.9 – 1.09 0.871 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.01 0.981 – 1.04 0.51 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.983 0.835 – 1.16 0.837 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 0.887 0.808 – 0.973 0.011 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.97 0.924 – 1.02 0.218 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.03 0.972 – 1.09 0.31 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.96 0.925 – 0.996 0.029 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 0.994 0.959 – 1.03 0.76 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 0.917 0.712 – 1.18 0.504 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.977 0.943 – 1.01 0.184 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.976 0.862 – 1.1 0.698 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.935 0.808 – 1.08 0.362 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.984 0.947 – 1.02 0.395 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.01 0.882 – 1.16 0.849 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 1.41 1.1 – 1.81 0.00708 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 0.983 0.952 – 1.02 0.296 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.15 0.874 – 1.53 0.313 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.897 0.723 – 1.11 0.324 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.83 0.712 – 0.969 0.0181 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 1.02 0.928 – 1.12 0.689 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 0.895 0.781 – 1.03 0.109 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 0.984 0.841 – 1.15 0.844 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.07 0.909 – 1.25 0.435 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 0.992 0.937 – 1.05 0.779 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 0.986 0.955 – 1.02 0.38 4260 42663 all phecode
916 Contusion Injuries & Poisonings 0.942 0.892 – 0.994 0.0307 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.93 0.796 – 1.08 0.355 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.97 0.874 – 1.08 0.571 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.987 0.865 – 1.13 0.844 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1 0.96 – 1.05 0.874 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.973 0.849 – 1.12 0.696 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.94 0.771 – 1.15 0.538 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.02 0.931 – 1.11 0.728 550 5509 all phecode
947 Urticaria Injuries & Poisonings 0.98 0.881 – 1.09 0.717 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 0.923 0.832 – 1.02 0.134 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.964 0.873 – 1.06 0.459 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.948 0.838 – 1.07 0.404 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.04 0.946 – 1.14 0.43 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.35 1.03 – 1.77 0.0314 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.16 0.921 – 1.47 0.204 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.989 0.974 – 1 0.177 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.991 0.974 – 1.01 0.258 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 0.917 0.829 – 1.02 0.0957 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.987 0.92 – 1.06 0.723 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.09 0.981 – 1.21 0.108 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.07 0.96 – 1.19 0.219 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.02 0.89 – 1.17 0.769 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.1 0.973 – 1.24 0.128 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.11 0.978 – 1.25 0.109 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.986 0.96 – 1.01 0.294 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.987 0.93 – 1.05 0.671 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.956 0.87 – 1.05 0.356 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.948 0.858 – 1.05 0.303 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.877 0.8 – 0.961 0.00507 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.981 0.9 – 1.07 0.651 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 0.933 0.89 – 0.977 0.00328 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.92 0.794 – 1.07 0.269 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.915 0.809 – 1.03 0.156 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.941 0.753 – 1.18 0.593 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 0.937 0.773 – 1.13 0.504 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.893 0.728 – 1.1 0.28 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.03 0.807 – 1.32 0.794 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.887 0.685 – 1.15 0.363 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.855 0.749 – 0.975 0.0197 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 0.91 0.843 – 0.983 0.0166 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.95 0.825 – 1.09 0.474 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.48 1.15 – 1.92 0.00266 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 0.942 0.77 – 1.15 0.565 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 1.08 0.89 – 1.3 0.446 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.08 0.875 – 1.34 0.471 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.01 0.971 – 1.05 0.704 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 0.997 0.96 – 1.03 0.864 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 0.997 0.96 – 1.03 0.864 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 0.994 0.967 – 1.02 0.647 5538 63928 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.01 0.957 – 1.06 0.811 1663 19453 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.06 0.951 – 1.19 0.275 316 4512 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1 0.913 – 1.1 0.996 514 6251 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 0.928 0.656 – 1.31 0.673 32 412 exclusion phecode
010 Tuberculosis Infectious Diseases 0.97 0.789 – 1.19 0.771 100 1154 exclusion phecode
038 Septicemia Infectious Diseases 0.974 0.932 – 1.02 0.249 2126 29197 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 0.95 0.859 – 1.05 0.319 415 5900 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 0.986 0.863 – 1.13 0.831 227 3457 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 0.96 0.936 – 0.984 0.001 6955 85937 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 0.968 0.921 – 1.02 0.204 1679 22196 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 0.987 0.924 – 1.05 0.688 976 11987 exclusion phecode
041.4 E. coli Infectious Diseases 0.955 0.906 – 1.01 0.085 1520 19569 exclusion phecode
053 Herpes zoster Infectious Diseases 0.936 0.819 – 1.07 0.328 225 2821 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.938 0.715 – 1.23 0.642 57 644 exclusion phecode
054 Herpes simplex Infectious Diseases 0.902 0.759 – 1.07 0.244 141 1606 exclusion phecode
070 Viral hepatitis Infectious Diseases 0.915 0.818 – 1.02 0.12 323 4477 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.03 0.774 – 1.38 0.829 48 549 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.966 0.77 – 1.21 0.768 73 968 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 0.841 0.704 – 1 0.0559 132 2012 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.05 0.891 – 1.25 0.537 140 2057 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.11 0.973 – 1.27 0.118 224 3107 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.05 0.834 – 1.33 0.664 73 1099 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.07 0.825 – 1.4 0.594 59 878 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.973 0.901 – 1.05 0.491 706 7578 exclusion phecode
079 Viral infection Infectious Diseases 0.99 0.945 – 1.04 0.665 1923 21181 exclusion phecode
079.1 Varicella infection Infectious Diseases 1.14 0.841 – 1.54 0.401 46 518 exclusion phecode
080 Postoperative infection Infectious Diseases 0.942 0.905 – 0.981 0.00342 2675 32311 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 0.932 0.882 – 0.985 0.0122 1363 17494 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.05 0.759 – 1.45 0.774 45 535 exclusion phecode
1000 Burns Injuries & Poisonings 0.991 0.892 – 1.1 0.865 381 4263 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 0.992 0.924 – 1.07 0.837 822 8739 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.01 0.975 – 1.04 0.606 3520 39155 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 0.858 0.74 – 0.995 0.043 191 2193 exclusion phecode
1005 Other symptoms Injuries & Poisonings 1.03 0.957 – 1.1 0.478 863 10313 exclusion phecode
1006 Crushing injury Injuries & Poisonings 1.01 0.859 – 1.18 0.944 176 1821 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 0.935 0.802 – 1.09 0.393 178 1913 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.01 0.93 – 1.09 0.897 707 7313 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 0.986 0.96 – 1.01 0.318 5883 62296 exclusion phecode
1010 Other tests Injuries & Poisonings 1.01 0.972 – 1.04 0.764 3788 42750 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.972 0.946 – 0.999 0.0416 5585 64404 exclusion phecode
1012 Late effect Injuries & Poisonings 0.988 0.775 – 1.26 0.923 76 764 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.01 0.871 – 1.16 0.928 199 2244 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.898 0.675 – 1.2 0.462 53 489 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 0.942 0.906 – 0.98 0.00317 2671 31277 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 0.981 0.962 – 1 0.0632 10738 116961 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.993 0.844 – 1.17 0.933 161 1992 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 1.01 0.857 – 1.19 0.911 157 1957 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.954 0.707 – 1.29 0.756 47 532 exclusion phecode
110.12 Althete's foot Infectious Diseases 0.969 0.771 – 1.22 0.788 77 994 exclusion phecode
112 Candidiasis Infectious Diseases 0.977 0.923 – 1.03 0.42 1280 15203 exclusion phecode
117 Mycoses Infectious Diseases 1.14 0.959 – 1.35 0.141 142 1917 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.26 1.01 – 1.58 0.0401 85 1129 exclusion phecode
130 Spirochetal infection Infectious Diseases 1.13 0.847 – 1.5 0.415 54 603 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 0.982 0.74 – 1.3 0.899 44 522 exclusion phecode
134 Helminthiases Infectious Diseases 0.967 0.778 – 1.2 0.765 85 996 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 0.947 0.741 – 1.21 0.66 70 838 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.99 0.828 – 1.18 0.916 124 1464 exclusion phecode
145 Cancer of mouth Neoplasms 1.03 0.938 – 1.14 0.501 440 4516 exclusion phecode
145.2 Cancer of tongue Neoplasms 0.991 0.864 – 1.14 0.895 217 2145 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.996 0.784 – 1.26 0.972 68 791 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.15 0.817 – 1.61 0.431 37 369 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.951 0.858 – 1.06 0.344 392 4321 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 0.902 0.77 – 1.06 0.205 170 1800 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.02 0.865 – 1.21 0.789 140 1718 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.06 0.763 – 1.47 0.729 40 382 exclusion phecode
150 Cancer of esophagus Neoplasms 0.964 0.875 – 1.06 0.453 441 4965 exclusion phecode
151 Cancer of stomach Neoplasms 0.952 0.851 – 1.06 0.381 331 3675 exclusion phecode
153 Colorectal cancer Neoplasms 0.956 0.921 – 0.993 0.0198 2982 31087 exclusion phecode
153.2 Colon cancer Neoplasms 0.944 0.902 – 0.989 0.0146 2015 20964 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.969 0.918 – 1.02 0.263 1419 14778 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.884 0.773 – 1.01 0.0715 220 2702 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.808 0.638 – 1.02 0.0764 69 1024 exclusion phecode
157 Pancreatic cancer Neoplasms 0.969 0.875 – 1.07 0.547 398 4402 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.945 0.874 – 1.02 0.152 686 7382 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.943 0.911 – 0.976 0.000882 3553 37731 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.861 0.722 – 1.03 0.0936 130 1326 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1 0.838 – 1.2 0.966 131 1394 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.869 0.724 – 1.04 0.133 122 1346 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 1.18 0.869 – 1.6 0.289 41 409 exclusion phecode
165 Cancer within the respiratory system Neoplasms 0.93 0.884 – 0.979 0.00579 1593 18688 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 0.906 0.855 – 0.961 0.000947 1233 14797 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 1.03 0.91 – 1.16 0.666 295 3027 exclusion phecode
170.1 Bone cancer Neoplasms 0.962 0.768 – 1.2 0.735 84 899 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1.04 0.908 – 1.2 0.545 225 2294 exclusion phecode
172 Skin cancer Neoplasms 1 0.98 – 1.02 0.946 9327 92779 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.981 0.937 – 1.03 0.432 1928 19087 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.981 0.936 – 1.03 0.41 1951 19315 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1 0.976 – 1.02 0.975 7542 74823 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 1.03 0.929 – 1.14 0.572 406 4415 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.878 0.734 – 1.05 0.155 128 1321 exclusion phecode
174 Breast cancer Neoplasms 0.971 0.951 – 0.992 0.00705 9487 97258 exclusion phecode
174.1 Breast cancer [female] Neoplasms 0.973 0.952 – 0.993 0.0103 9353 95789 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.978 0.956 – 0.999 0.0428 8789 90219 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.876 0.715 – 1.07 0.2 93 905 exclusion phecode
175 Acquired absence of breast Neoplasms 0.944 0.899 – 0.991 0.0208 1768 18613 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 0.97 0.924 – 1.02 0.219 1779 18031 exclusion phecode
180.1 Cervical cancer Neoplasms 0.961 0.835 – 1.1 0.574 214 2176 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.974 0.927 – 1.02 0.297 1703 17213 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.979 0.913 – 1.05 0.557 847 9520 exclusion phecode
184 Cancer of other female genital organs Neoplasms 0.985 0.924 – 1.05 0.653 1010 10505 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.98 0.908 – 1.06 0.614 715 7284 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.984 0.911 – 1.06 0.692 693 7046 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.02 0.885 – 1.17 0.811 219 2371 exclusion phecode
185 Cancer of prostate Neoplasms 0.99 0.957 – 1.02 0.582 3690 35865 exclusion phecode
187 Cancer of other male genital organs Neoplasms 1.04 0.922 – 1.17 0.531 304 3153 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.31 0.941 – 1.82 0.111 40 438 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 1.06 0.918 – 1.23 0.411 199 2112 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.848 0.668 – 1.08 0.175 75 735 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.97 0.928 – 1.01 0.184 2136 27012 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.931 0.84 – 1.03 0.169 403 7221 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.922 0.83 – 1.02 0.132 383 6951 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.12 0.786 – 1.59 0.533 31 434 exclusion phecode
189.2 Cancer of bladder Neoplasms 0.963 0.911 – 1.02 0.182 1356 15398 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.975 0.919 – 1.03 0.406 1195 13676 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.21 0.927 – 1.59 0.159 58 938 exclusion phecode
190 Cancer of eye Neoplasms 0.911 0.759 – 1.09 0.318 122 1233 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.934 0.849 – 1.03 0.155 471 4848 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.953 0.859 – 1.06 0.372 389 3944 exclusion phecode
191.11 Cancer of brain Neoplasms 0.932 0.836 – 1.04 0.2 362 3669 exclusion phecode
193 Thyroid cancer Neoplasms 0.919 0.805 – 1.05 0.211 234 2652 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.02 0.79 – 1.31 0.893 58 701 exclusion phecode
195 Cancer, suspected or other Neoplasms 0.972 0.953 – 0.991 0.00421 11114 116438 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 0.97 0.951 – 0.99 0.003 10621 111911 exclusion phecode
197 Chemotherapy Neoplasms 0.979 0.962 – 0.996 0.016 14014 156042 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 0.967 0.942 – 0.993 0.0121 6170 67750 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.979 0.946 – 1.01 0.222 3642 38998 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.981 0.928 – 1.04 0.501 1380 15988 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.974 0.913 – 1.04 0.413 1009 11039 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 0.955 0.908 – 1 0.0733 1657 18449 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.993 0.908 – 1.09 0.881 527 6027 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.01 0.955 – 1.07 0.716 1291 14889 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.98 0.818 – 1.17 0.826 119 1353 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 0.948 0.884 – 1.02 0.138 841 10306 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.14 0.84 – 1.55 0.397 39 706 exclusion phecode
200 Myeloproliferative disease Neoplasms 0.98 0.892 – 1.08 0.666 480 6747 exclusion phecode
200.1 Polycythemia vera Neoplasms 0.827 0.704 – 0.972 0.0209 162 2584 exclusion phecode
201 Hodgkin's disease Neoplasms 1.11 0.946 – 1.3 0.201 160 1976 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.06 1 – 1.12 0.0423 1288 15846 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.08 1.01 – 1.15 0.0229 1012 12512 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.1 0.959 – 1.26 0.177 220 2507 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.1 0.984 – 1.23 0.0943 328 4022 exclusion phecode
204 Leukemia Neoplasms 1.01 0.945 – 1.08 0.758 926 11320 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1.05 0.939 – 1.18 0.378 317 3872 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.22 0.87 – 1.72 0.247 34 413 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.06 0.941 – 1.2 0.322 270 3393 exclusion phecode
204.2 Myeloid leukemia Neoplasms 0.976 0.861 – 1.11 0.698 271 3228 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.96 0.823 – 1.12 0.602 182 2296 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.02 0.832 – 1.25 0.854 103 1010 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.03 0.917 – 1.17 0.581 287 3744 exclusion phecode
208 Benign neoplasm of colon Neoplasms 0.967 0.95 – 0.985 0.000329 12795 134394 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.925 0.855 – 1 0.0509 681 7213 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.963 0.93 – 0.997 0.0319 3571 37441 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.14 0.999 – 1.3 0.0521 234 2505 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.97 0.849 – 1.11 0.66 244 2393 exclusion phecode
214 Lipoma Neoplasms 0.961 0.932 – 0.991 0.0121 4392 45251 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.974 0.939 – 1.01 0.144 3277 33835 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.05 0.975 – 1.13 0.207 820 8233 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.987 0.961 – 1.01 0.353 5724 57581 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.919 0.833 – 1.02 0.0973 435 4529 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.916 0.827 – 1.01 0.0939 409 4246 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.98 0.958 – 1 0.0905 8074 81251 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.979 0.957 – 1 0.0644 8240 82633 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.01 0.888 – 1.14 0.931 269 2832 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.963 0.907 – 1.02 0.226 1120 11458 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.04 0.888 – 1.21 0.642 173 1750 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 1.15 0.93 – 1.42 0.199 94 1038 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.02 0.831 – 1.26 0.821 100 1152 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.964 0.763 – 1.22 0.755 78 954 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.784 0.553 – 1.11 0.171 37 458 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.05 0.962 – 1.15 0.273 563 5999 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.05 0.964 – 1.15 0.251 528 5694 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.09 0.796 – 1.5 0.589 43 455 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.01 0.874 – 1.17 0.892 196 2039 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.992 0.909 – 1.08 0.853 548 6287 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.951 0.784 – 1.15 0.612 106 1354 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.993 0.869 – 1.13 0.912 237 2662 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.01 0.873 – 1.17 0.883 204 2262 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.986 0.928 – 1.05 0.657 1141 11659 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.983 0.937 – 1.03 0.493 1842 18187 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.915 0.828 – 1.01 0.0808 414 4535 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.913 0.848 – 0.983 0.0153 779 8411 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.905 0.81 – 1.01 0.0744 357 3598 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.931 0.845 – 1.03 0.149 451 5090 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.02 0.963 – 1.09 0.468 1162 13999 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 1.04 0.928 – 1.16 0.509 327 3632 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 0.826 0.641 – 1.06 0.139 57 715 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.997 0.81 – 1.23 0.978 95 1059 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 0.997 0.976 – 1.02 0.795 9219 108660 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.927 0.857 – 1 0.0549 700 8273 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.968 0.753 – 1.25 0.803 60 769 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1 0.981 – 1.03 0.794 8765 103937 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.91 0.787 – 1.05 0.201 201 2279 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.893 0.756 – 1.06 0.186 153 1716 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.887 0.749 – 1.05 0.167 145 1639 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 0.962 0.849 – 1.09 0.544 260 3014 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 0.953 0.935 – 0.972 1.63e-06 10925 131077 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.02 0.97 – 1.08 0.417 1489 19737 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.06 0.892 – 1.26 0.517 140 1800 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.96 0.553 – 1.67 0.885 8 556 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.04 0.911 – 1.19 0.557 222 3357 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.1 0.838 – 1.43 0.506 51 1141 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.945 0.925 – 0.965 1.13e-07 9579 118577 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.804 0.623 – 1.04 0.0944 61 768 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.01 0.692 – 1.48 0.952 25 1338 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.862 0.779 – 0.954 0.00393 397 6711 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 0.809 0.694 – 0.942 0.00643 164 3447 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 0.93 0.839 – 1.03 0.167 400 4888 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.961 0.821 – 1.12 0.62 172 1858 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.88 0.769 – 1.01 0.0617 228 3014 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.05 0.865 – 1.28 0.61 104 1107 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.792 0.661 – 0.949 0.0113 124 2404 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.93 0.856 – 1.01 0.0837 596 9087 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 0.986 0.897 – 1.08 0.768 451 6676 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.09 0.996 – 1.2 0.0615 461 6281 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.1 0.994 – 1.21 0.0642 417 5639 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.19 0.915 – 1.54 0.198 59 1003 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.96 0.868 – 1.06 0.436 413 4880 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.967 0.8 – 1.17 0.724 122 1392 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.898 0.693 – 1.16 0.414 61 699 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.91 0.767 – 1.08 0.279 143 1869 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.865 0.642 – 1.16 0.339 47 715 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.13 0.925 – 1.37 0.238 107 1033 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.932 0.834 – 1.04 0.213 337 4714 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.824 0.667 – 1.02 0.0717 90 1352 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.819 0.626 – 1.07 0.146 52 805 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.846 0.606 – 1.18 0.326 38 549 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1 0.864 – 1.17 0.961 185 2651 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.01 0.866 – 1.17 0.934 185 2645 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.899 0.779 – 1.04 0.143 204 2141 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.872 0.748 – 1.02 0.0808 174 1876 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1.07 0.859 – 1.33 0.547 87 1131 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.09 0.867 – 1.37 0.46 80 1064 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.14 0.88 – 1.48 0.316 55 752 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.91 0.742 – 1.12 0.366 102 1134 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.13 0.942 – 1.37 0.184 117 1414 exclusion phecode
260.1 Cachexia Endocrine/metabolic 0.94 0.646 – 1.37 0.749 27 340 exclusion phecode
260.6 Anorexia Endocrine/metabolic 0.942 0.86 – 1.03 0.202 494 5856 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1 0.93 – 1.08 0.922 692 8706 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.01 0.914 – 1.11 0.906 440 5454 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.06 0.934 – 1.2 0.369 258 3312 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.34 0.976 – 1.84 0.0705 36 575 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.916 0.774 – 1.08 0.308 152 1775 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.13 0.957 – 1.32 0.153 158 2372 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.988 0.843 – 1.16 0.879 160 2051 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.988 0.829 – 1.18 0.894 134 1749 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.03 0.835 – 1.27 0.784 94 1263 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1.15 0.882 – 1.51 0.298 55 764 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.935 0.675 – 1.3 0.689 36 475 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.975 0.805 – 1.18 0.793 109 1184 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.989 0.809 – 1.21 0.912 99 1039 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.981 0.966 – 0.995 0.00916 20417 170572 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.981 0.966 – 0.995 0.00878 20374 170389 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.981 0.966 – 0.996 0.0129 18889 164486 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1 0.72 – 1.39 0.998 38 411 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.894 0.723 – 1.1 0.297 84 1154 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.01 0.84 – 1.22 0.888 118 1442 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.03 0.977 – 1.08 0.285 1596 24798 exclusion phecode
274.1 Gout Endocrine/metabolic 1.05 0.986 – 1.11 0.135 1237 20817 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.24 0.942 – 1.63 0.126 51 735 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.974 0.879 – 1.08 0.621 384 4360 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.971 0.873 – 1.08 0.59 356 3988 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.956 0.901 – 1.01 0.141 1172 14742 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.909 0.822 – 1.01 0.0649 423 4588 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 0.935 0.811 – 1.08 0.349 200 2573 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.03 0.946 – 1.11 0.536 610 8470 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.989 0.815 – 1.2 0.911 100 1209 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 0.972 0.94 – 1.01 0.0984 3665 50343 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 0.997 0.953 – 1.04 0.882 2110 28095 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.02 0.85 – 1.22 0.835 121 1585 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.03 0.966 – 1.1 0.375 1071 12445 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1 0.897 – 1.12 0.938 311 6533 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 0.957 0.889 – 1.03 0.24 773 10104 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.853 0.776 – 0.938 0.00101 470 7952 exclusion phecode
276.41 Acidosis Endocrine/metabolic 0.843 0.763 – 0.931 0.000754 420 7243 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 0.968 0.724 – 1.29 0.825 52 746 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 0.977 0.925 – 1.03 0.406 1409 19646 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 0.981 0.834 – 1.15 0.819 151 3022 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.02 0.807 – 1.28 0.897 88 971 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 0.996 0.911 – 1.09 0.933 517 6497 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.13 0.986 – 1.29 0.0783 238 2573 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.21 1.02 – 1.45 0.0334 132 1611 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.967 0.652 – 1.43 0.866 26 367 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.933 0.908 – 0.958 5.33e-07 5600 79880 exclusion phecode
278.1 Obesity Endocrine/metabolic 0.931 0.906 – 0.957 3.05e-07 5501 78655 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 1.05 0.808 – 1.35 0.734 61 686 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.932 0.636 – 1.36 0.715 32 510 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.07 0.905 – 1.28 0.411 144 1853 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.11 0.924 – 1.34 0.257 121 1545 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.23 0.972 – 1.55 0.085 77 1012 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 0.95 0.809 – 1.12 0.533 164 1594 exclusion phecode
280 Iron deficiency anemias Hematopoietic 0.975 0.947 – 1 0.101 4717 56023 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.983 0.953 – 1.01 0.259 4497 53665 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.879 0.783 – 0.986 0.0281 322 3555 exclusion phecode
281 Other deficiency anemia Hematopoietic 0.976 0.9 – 1.06 0.555 613 8034 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 0.977 0.9 – 1.06 0.581 593 7703 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1 0.913 – 1.11 0.925 430 5434 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.866 0.71 – 1.05 0.153 103 1327 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 0.861 0.693 – 1.07 0.176 80 1277 exclusion phecode
281.9 Deficiency anemias Hematopoietic 0.934 0.641 – 1.36 0.724 23 369 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.05 0.837 – 1.31 0.686 77 1087 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.02 0.719 – 1.44 0.928 33 406 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.864 0.645 – 1.16 0.328 42 618 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.08 0.829 – 1.41 0.566 59 972 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 1 0.745 – 1.35 0.977 45 730 exclusion phecode
284 Aplastic anemia Hematopoietic 1.06 0.917 – 1.22 0.44 200 3051 exclusion phecode
285 Other anemias Hematopoietic 0.971 0.947 – 0.994 0.0161 7059 87513 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.04 0.898 – 1.21 0.58 185 2064 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 0.932 0.825 – 1.05 0.262 268 4887 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.946 0.829 – 1.08 0.415 235 2923 exclusion phecode
286 Coagulation defects Hematopoietic 0.985 0.902 – 1.08 0.737 557 6766 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.97 0.863 – 1.09 0.613 317 3459 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.977 0.779 – 1.23 0.843 74 734 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.944 0.815 – 1.09 0.442 201 2233 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.3 0.946 – 1.79 0.105 38 460 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.28 0.879 – 1.86 0.2 29 569 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.01 0.884 – 1.16 0.844 218 2823 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.01 0.94 – 1.08 0.836 868 11543 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.11 0.891 – 1.38 0.354 80 916 exclusion phecode
287.2 Allergic purpura Hematopoietic 1.18 0.823 – 1.69 0.371 30 395 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 0.982 0.915 – 1.05 0.623 812 10830 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.05 0.913 – 1.2 0.51 214 2939 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.966 0.677 – 1.38 0.847 32 507 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.01 0.968 – 1.05 0.64 2279 27246 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.02 0.97 – 1.06 0.504 1930 22983 exclusion phecode
288.11 Neutropenia Hematopoietic 1.02 0.969 – 1.06 0.523 1937 23042 exclusion phecode
288.3 Eosinophilia Hematopoietic 1.03 0.754 – 1.41 0.844 40 499 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.948 0.863 – 1.04 0.26 474 6221 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.1 0.935 – 1.28 0.258 164 2167 exclusion phecode
289.4 Lymphadenitis Hematopoietic 0.963 0.915 – 1.01 0.152 1575 18736 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1 0.89 – 1.13 0.944 291 3627 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 0.905 0.76 – 1.08 0.26 133 2006 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 0.729 0.521 – 1.02 0.0656 38 649 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.947 0.888 – 1.01 0.0973 1010 12458 exclusion phecode
290.1 Dementias Mental Disorders 0.935 0.857 – 1.02 0.132 540 6269 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 1 0.883 – 1.14 0.941 252 2750 exclusion phecode
290.16 Vascular dementia Mental Disorders 0.978 0.804 – 1.19 0.824 99 1219 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.01 0.901 – 1.13 0.882 328 4252 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.774 0.561 – 1.07 0.121 42 558 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.959 0.876 – 1.05 0.363 499 6087 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.998 0.81 – 1.23 0.981 95 1045 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.971 0.83 – 1.14 0.713 163 1978 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 0.921 0.812 – 1.04 0.197 255 3192 exclusion phecode
292 Neurological disorders Mental Disorders 0.957 0.92 – 0.995 0.0282 2712 31905 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.977 0.913 – 1.05 0.502 906 10596 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.987 0.804 – 1.21 0.899 99 1299 exclusion phecode
292.3 Memory loss Mental Disorders 0.954 0.867 – 1.05 0.336 469 4916 exclusion phecode
292.4 Altered mental status Mental Disorders 0.911 0.86 – 0.966 0.00187 1211 14671 exclusion phecode
292.6 Hallucinations Mental Disorders 0.964 0.825 – 1.13 0.642 171 2166 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 0.967 0.916 – 1.02 0.231 1419 15198 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.976 0.899 – 1.06 0.566 605 6623 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.01 0.918 – 1.1 0.894 493 6382 exclusion phecode
295.1 Schizophrenia Mental Disorders 0.995 0.888 – 1.11 0.927 326 4364 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.09 0.903 – 1.33 0.355 111 1363 exclusion phecode
295.3 Psychosis Mental Disorders 0.996 0.817 – 1.21 0.968 101 1317 exclusion phecode
296 Mood disorders Mental Disorders 0.963 0.941 – 0.985 0.00118 8082 94942 exclusion phecode
296.1 Bipolar Mental Disorders 0.962 0.888 – 1.04 0.349 632 8089 exclusion phecode
296.2 Depression Mental Disorders 0.962 0.94 – 0.985 0.00115 7697 90087 exclusion phecode
296.22 Major depressive disorder Mental Disorders 0.956 0.837 – 1.09 0.512 228 2742 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.01 0.878 – 1.16 0.913 208 2413 exclusion phecode
300 Anxiety disorders Mental Disorders 0.976 0.947 – 1.01 0.119 4624 51851 exclusion phecode
300.1 Anxiety disorder Mental Disorders 0.976 0.946 – 1.01 0.13 4282 47836 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 1.09 0.893 – 1.32 0.41 109 1153 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.992 0.902 – 1.09 0.86 474 5403 exclusion phecode
300.13 Phobia Mental Disorders 0.945 0.844 – 1.06 0.322 326 3766 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.13 0.927 – 1.39 0.223 97 1080 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 0.862 0.611 – 1.22 0.398 37 419 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.1 0.882 – 1.37 0.4 86 965 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.01 0.797 – 1.28 0.94 80 891 exclusion phecode
301 Personality disorders Mental Disorders 1.15 0.998 – 1.32 0.0527 203 2700 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.11 0.887 – 1.4 0.355 74 1010 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 0.851 0.725 – 1 0.0501 162 1890 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.03 0.923 – 1.16 0.557 327 3543 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 1.07 0.94 – 1.22 0.306 252 2625 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.995 0.799 – 1.24 0.965 82 960 exclusion phecode
304 Adjustment reaction Mental Disorders 0.979 0.848 – 1.13 0.777 202 2288 exclusion phecode
305.2 Eating disorder Mental Disorders 0.849 0.661 – 1.09 0.198 73 763 exclusion phecode
306 Other mental disorder Mental Disorders 0.948 0.933 – 0.963 4.85e-11 17030 167354 exclusion phecode
306.9 Tension headache Mental Disorders 0.853 0.745 – 0.977 0.0219 218 2489 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 1.08 0.822 – 1.42 0.585 54 593 exclusion phecode
313.3 Autism Mental Disorders 1.23 0.89 – 1.69 0.212 39 409 exclusion phecode
315 Develomental delays and disorders Mental Disorders 0.968 0.837 – 1.12 0.661 200 2513 exclusion phecode
315.1 Learning disorder Mental Disorders 0.954 0.766 – 1.19 0.672 83 1248 exclusion phecode
315.2 Speech and language disorder Mental Disorders 1.15 0.865 – 1.53 0.335 50 615 exclusion phecode
316 Substance addiction and disorders Mental Disorders 0.936 0.903 – 0.97 0.000242 3375 39026 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.704 0.496 – 1 0.0499 31 449 exclusion phecode
317 Alcohol-related disorders Mental Disorders 0.97 0.949 – 0.992 0.007 8591 92459 exclusion phecode
317.1 Alcoholism Mental Disorders 0.979 0.953 – 1 0.11 6050 64215 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 0.895 0.814 – 0.985 0.0228 450 6050 exclusion phecode
318 Tobacco use disorder Mental Disorders 0.915 0.897 – 0.933 2.42e-19 11090 136722 exclusion phecode
320 Meningitis Neurological 0.925 0.824 – 1.04 0.191 314 3432 exclusion phecode
323 Encephalitis Neurological 1.08 0.948 – 1.23 0.251 242 2561 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 1 0.784 – 1.29 0.97 62 590 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 0.903 0.776 – 1.05 0.188 186 2017 exclusion phecode
327 Sleep disorders Neurological 0.973 0.903 – 1.05 0.472 753 8299 exclusion phecode
327.3 Sleep apnea Neurological 0.975 0.935 – 1.02 0.22 2509 31613 exclusion phecode
327.4 Insomnia Neurological 1.02 0.846 – 1.24 0.812 106 1206 exclusion phecode
327.41 Organic or persistent insomnia Neurological 0.989 0.807 – 1.21 0.918 89 1012 exclusion phecode
331 Other cerebral degenerations Neurological 1 0.928 – 1.09 0.92 688 7941 exclusion phecode
331.1 Hydrocephalus Neurological 1 0.892 – 1.12 0.991 320 3620 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 0.979 0.86 – 1.12 0.754 245 2859 exclusion phecode
332 Parkinson's disease Neurological 0.972 0.898 – 1.05 0.469 696 7283 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.987 0.905 – 1.08 0.763 563 6369 exclusion phecode
333.1 Essential tremor Neurological 1.01 0.835 – 1.22 0.93 119 1443 exclusion phecode
333.2 Myoclonus Neurological 1.14 0.882 – 1.46 0.323 65 700 exclusion phecode
333.4 Torsion dystonia Neurological 1.03 0.881 – 1.2 0.716 169 1872 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.03 0.969 – 1.1 0.338 1142 12828 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.08 0.836 – 1.39 0.565 65 836 exclusion phecode
334.2 Anterior horn cell disease Neurological 0.994 0.842 – 1.17 0.944 159 1626 exclusion phecode
335 Multiple sclerosis Neurological 1.02 0.957 – 1.09 0.522 1001 10396 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 0.915 0.779 – 1.07 0.279 157 1874 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 0.893 0.638 – 1.25 0.513 36 467 exclusion phecode
338 Pain Neurological 0.945 0.858 – 1.04 0.248 465 5734 exclusion phecode
338.1 Acute pain Neurological 0.905 0.789 – 1.04 0.149 226 2898 exclusion phecode
338.2 Chronic pain Neurological 0.977 0.855 – 1.12 0.731 242 2934 exclusion phecode
339 Other headache syndromes Neurological 0.984 0.957 – 1.01 0.272 5457 59083 exclusion phecode
340 Migraine Neurological 0.971 0.928 – 1.02 0.192 2104 22427 exclusion phecode
340.1 Migrain with aura Neurological 0.952 0.804 – 1.13 0.57 154 1692 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.13 0.978 – 1.31 0.0962 196 1993 exclusion phecode
342 Hemiplegia Neurological 0.925 0.861 – 0.994 0.0331 811 10529 exclusion phecode
343 Infantile cerebral palsy Neurological 1.06 0.857 – 1.3 0.609 101 1092 exclusion phecode
344 Other paralytic syndromes Neurological 1.02 0.923 – 1.13 0.677 415 4841 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.983 0.949 – 1.02 0.347 3449 36984 exclusion phecode
345.1 Epilepsy Neurological 0.965 0.886 – 1.05 0.418 600 6422 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 0.994 0.886 – 1.12 0.923 313 3237 exclusion phecode
345.12 Partial epilepsy Neurological 0.962 0.83 – 1.12 0.609 200 2113 exclusion phecode
345.3 Convulsions Neurological 0.986 0.935 – 1.04 0.591 1513 16471 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.946 0.769 – 1.16 0.597 91 1064 exclusion phecode
348 Other conditions of brain Neurological 1.04 0.947 – 1.14 0.414 469 5731 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.1 0.934 – 1.29 0.257 159 2021 exclusion phecode
348.4 Cerebral cysts Neurological 0.938 0.76 – 1.16 0.553 97 1023 exclusion phecode
348.7 Coma Neurological 1 0.88 – 1.14 0.993 244 2540 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 0.991 0.837 – 1.17 0.916 147 1803 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 0.991 0.874 – 1.12 0.893 266 2780 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.02 0.887 – 1.16 0.826 221 2482 exclusion phecode
350 Abnormal movement Neurological 0.958 0.91 – 1.01 0.109 1558 18808 exclusion phecode
350.1 Abnormal involuntary movements Neurological 0.971 0.889 – 1.06 0.511 540 6480 exclusion phecode
350.2 Abnormality of gait Neurological 0.936 0.874 – 1 0.0601 884 10945 exclusion phecode
350.3 Lack of coordination Neurological 0.997 0.871 – 1.14 0.966 223 2634 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.864 0.62 – 1.2 0.386 39 397 exclusion phecode
351 Other peripheral nerve disorders Neurological 0.988 0.966 – 1.01 0.285 8509 92624 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.04 0.973 – 1.11 0.244 903 9985 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.08 0.959 – 1.21 0.211 319 3438 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.01 0.924 – 1.1 0.893 565 6376 exclusion phecode
353 Nerve root and plexus disorders Neurological 0.968 0.896 – 1.05 0.42 692 8200 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.868 0.693 – 1.09 0.214 79 883 exclusion phecode
353.2 Nerve root lesions Neurological 1.04 0.741 – 1.45 0.837 36 413 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.887 0.714 – 1.1 0.281 93 1075 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.02 0.947 – 1.1 0.611 759 9463 exclusion phecode
358 Myoneural disorders Neurological 0.977 0.809 – 1.18 0.808 113 1447 exclusion phecode
358.1 Myasthenia gravis Neurological 0.976 0.805 – 1.18 0.809 105 1336 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.968 0.851 – 1.1 0.618 245 3358 exclusion phecode
359.1 Muscular dystrophies Neurological 0.883 0.682 – 1.14 0.341 61 888 exclusion phecode
359.2 Myopathy Neurological 0.987 0.854 – 1.14 0.863 190 2586 exclusion phecode
360 Disorders of the globe Sense Organs 1.14 0.991 – 1.3 0.0682 226 2287 exclusion phecode
360.2 Progressive myopia Sense Organs 1.1 0.938 – 1.29 0.239 167 1721 exclusion phecode
361 Retinal detachments and defects Sense Organs 1.03 0.99 – 1.08 0.135 2307 22703 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.03 0.967 – 1.1 0.346 980 9779 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.855 0.622 – 1.18 0.335 40 490 exclusion phecode
362 Other retinal disorders Sense Organs 0.962 0.923 – 1 0.0743 2379 25973 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.951 0.9 – 1.01 0.0771 1374 14566 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.951 0.9 – 1.01 0.0776 1372 14540 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.27 1.04 – 1.56 0.0187 106 1132 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1.14 0.898 – 1.46 0.276 76 683 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.01 0.924 – 1.11 0.771 475 5694 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 1.03 0.854 – 1.24 0.771 126 1302 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.877 0.667 – 1.15 0.348 61 584 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.838 0.668 – 1.05 0.129 79 801 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.12 0.908 – 1.38 0.29 104 1221 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.99 0.701 – 1.4 0.952 34 506 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.96 0.87 – 1.06 0.407 440 4556 exclusion phecode
364.1 Corneal opacity Sense Organs 1.06 0.817 – 1.36 0.679 58 650 exclusion phecode
364.2 Corneal edema Sense Organs 0.846 0.615 – 1.16 0.305 43 547 exclusion phecode
364.4 Corneal degenerations Sense Organs 1.03 0.873 – 1.22 0.7 149 1459 exclusion phecode
364.41 Keratoconus Sense Organs 1.02 0.8 – 1.31 0.848 66 667 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.954 0.801 – 1.14 0.594 136 1407 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.859 0.673 – 1.1 0.223 69 706 exclusion phecode
365 Glaucoma Sense Organs 0.974 0.937 – 1.01 0.174 2838 29671 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 0.965 0.891 – 1.04 0.374 674 6777 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.963 0.889 – 1.04 0.358 670 6746 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.1 0.998 – 1.21 0.0548 477 4805 exclusion phecode
366 Cataract Sense Organs 0.987 0.969 – 1.01 0.169 12277 115766 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.973 0.71 – 1.33 0.866 42 517 exclusion phecode
366.2 Senile cataract Sense Organs 0.995 0.967 – 1.02 0.74 5021 54573 exclusion phecode
366.3 Traumatic cataract Sense Organs 1.2 0.943 – 1.53 0.138 69 681 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.05 0.994 – 1.1 0.0865 1610 16847 exclusion phecode
367.1 Myopia Sense Organs 1.03 0.957 – 1.1 0.475 880 8778 exclusion phecode
367.2 Astigmatism Sense Organs 1.08 0.907 – 1.29 0.38 124 1340 exclusion phecode
367.8 Hypermetropia Sense Organs 1.02 0.871 – 1.2 0.782 162 1737 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.07 0.973 – 1.19 0.156 439 4993 exclusion phecode
368 Visual disturbances Sense Organs 0.991 0.946 – 1.04 0.72 1896 21389 exclusion phecode
368.1 Amblyopia Sense Organs 0.939 0.838 – 1.05 0.278 320 3683 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.02 0.925 – 1.12 0.724 454 5275 exclusion phecode
368.3 Anisometropia Sense Organs 1.15 0.937 – 1.4 0.183 103 1123 exclusion phecode
368.4 Visual field defects Sense Organs 1.1 0.956 – 1.27 0.181 209 2315 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 1.03 0.927 – 1.14 0.61 395 4538 exclusion phecode
369 Infection of the eye Sense Organs 1 0.9 – 1.11 0.994 353 4013 exclusion phecode
369.2 Eye infection, viral Sense Organs 1.14 0.912 – 1.41 0.254 72 887 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.91 0.767 – 1.08 0.284 131 1554 exclusion phecode
370 Keratitis Sense Organs 0.887 0.761 – 1.03 0.126 190 2088 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.793 0.645 – 0.975 0.0281 97 1021 exclusion phecode
371 Inflammation of the eye Sense Organs 1.03 0.984 – 1.07 0.209 2192 22200 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.03 0.921 – 1.16 0.568 307 3471 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 1.02 0.97 – 1.07 0.45 1752 17237 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.05 0.957 – 1.15 0.32 529 5408 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.969 0.937 – 1 0.0599 3803 40161 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.972 0.896 – 1.05 0.496 641 6965 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 1.01 0.955 – 1.07 0.678 1222 12800 exclusion phecode
375 Disorders of lacrimal system Sense Organs 1 0.95 – 1.06 0.969 1523 15626 exclusion phecode
375.2 Epiphora Sense Organs 0.945 0.871 – 1.03 0.174 636 6274 exclusion phecode
376 Disorders of the orbit Sense Organs 0.997 0.751 – 1.32 0.984 52 610 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.04 0.906 – 1.19 0.593 228 2651 exclusion phecode
377.1 Optic atrophy Sense Organs 1.17 0.833 – 1.64 0.366 34 417 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.02 0.827 – 1.26 0.859 87 959 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.976 0.913 – 1.04 0.466 958 10370 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.977 0.902 – 1.06 0.574 651 6823 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.927 0.769 – 1.12 0.427 125 1501 exclusion phecode
378.5 Paralytic strabismus Sense Organs 0.966 0.829 – 1.13 0.662 171 1962 exclusion phecode
379 Other disorders of eye Sense Organs 1.02 0.98 – 1.07 0.294 2311 25287 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 1.04 0.971 – 1.12 0.257 875 9435 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.03 0.965 – 1.09 0.407 1086 12029 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 0.957 0.709 – 1.29 0.776 49 522 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1 0.885 – 1.14 0.965 262 2833 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.702 0.573 – 0.859 0.000596 102 1236 exclusion phecode
380 Disorders of external ear Sense Organs 0.999 0.908 – 1.1 0.989 448 4445 exclusion phecode
380.1 Otitis externa Sense Organs 0.929 0.831 – 1.04 0.192 342 3761 exclusion phecode
380.4 Impacted cerumen Sense Organs 1.06 0.936 – 1.21 0.344 250 2575 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.984 0.932 – 1.04 0.567 1414 15684 exclusion phecode
381.1 Otitis media Sense Organs 0.995 0.937 – 1.06 0.883 1156 12856 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.924 0.847 – 1.01 0.0756 553 6278 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.927 0.777 – 1.11 0.399 135 1457 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.963 0.795 – 1.16 0.695 113 1243 exclusion phecode
381.9 Otorrhea Sense Organs 0.917 0.787 – 1.07 0.261 185 2030 exclusion phecode
382 Otalgia Sense Organs 0.989 0.861 – 1.14 0.873 219 2306 exclusion phecode
383 Otosclerosis Sense Organs 0.967 0.845 – 1.11 0.633 232 2353 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 0.968 0.904 – 1.04 0.345 919 9595 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 0.954 0.884 – 1.03 0.233 732 7653 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.951 0.87 – 1.04 0.274 527 5736 exclusion phecode
385.3 Cholesteatoma Sense Organs 0.923 0.833 – 1.02 0.129 400 4423 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.899 0.767 – 1.05 0.186 170 1806 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.97 0.913 – 1.03 0.323 1156 12518 exclusion phecode
386.1 Meniere's disease Sense Organs 0.98 0.881 – 1.09 0.715 369 4126 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.946 0.83 – 1.08 0.411 250 2655 exclusion phecode
386.3 Labyrinthitis Sense Organs 0.993 0.908 – 1.09 0.88 515 5560 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.963 0.927 – 1 0.0539 2850 32587 exclusion phecode
388 Other disorders of ear Sense Organs 0.893 0.751 – 1.06 0.201 141 1463 exclusion phecode
389 Hearing loss Sense Organs 1.01 0.969 – 1.05 0.665 2628 29264 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.973 0.863 – 1.1 0.657 296 3179 exclusion phecode
389.2 Conductive hearing loss Sense Organs 0.908 0.806 – 1.02 0.116 296 3354 exclusion phecode
389.4 Tinnitus Sense Organs 0.964 0.861 – 1.08 0.53 336 3644 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 0.989 0.951 – 1.03 0.601 2638 32790 exclusion phecode
394.2 Mitral valve disease Circulatory System 0.987 0.938 – 1.04 0.606 1639 20116 exclusion phecode
394.3 Aortic valve disease Circulatory System 0.991 0.915 – 1.07 0.824 661 8535 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 0.995 0.912 – 1.08 0.904 555 7030 exclusion phecode
395 Heart valve disorders Circulatory System 0.982 0.941 – 1.03 0.413 2254 28234 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.993 0.944 – 1.05 0.801 1586 19409 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.962 0.808 – 1.15 0.663 132 1822 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.04 0.803 – 1.34 0.773 57 709 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.771 0.585 – 1.02 0.066 51 657 exclusion phecode
395.6 Heart valve replaced Circulatory System 0.945 0.875 – 1.02 0.142 743 9813 exclusion phecode
396 Abnormal heart sounds Circulatory System 0.933 0.862 – 1.01 0.0864 700 7655 exclusion phecode
401 Hypertension Circulatory System 0.974 0.963 – 0.984 1.05e-06 43185 207901 exclusion phecode
401.1 Essential hypertension Circulatory System 0.973 0.963 – 0.984 7.17e-07 43131 207712 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.01 0.906 – 1.12 0.884 349 13252 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 0.868 0.739 – 1.02 0.0824 157 2564 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.16 1.01 – 1.34 0.0369 192 10832 exclusion phecode
401.3 Other hypertensive complications Circulatory System 0.693 0.493 – 0.973 0.0342 29 1048 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 0.987 0.922 – 1.06 0.711 908 10889 exclusion phecode
411 Ischemic Heart Disease Circulatory System 0.971 0.955 – 0.986 0.000251 17437 150784 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.954 0.918 – 0.992 0.0168 2818 35061 exclusion phecode
411.2 Myocardial infarction Circulatory System 0.963 0.939 – 0.988 0.00415 6320 76419 exclusion phecode
411.3 Angina pectoris Circulatory System 0.963 0.942 – 0.984 0.000726 8723 98965 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 0.968 0.949 – 0.987 0.00124 11218 107549 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.999 0.902 – 1.11 0.983 424 4851 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.954 0.932 – 0.977 7.98e-05 7773 89870 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.931 0.862 – 1.01 0.0713 695 8291 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 0.957 0.894 – 1.03 0.21 879 12319 exclusion phecode
414.2 ASCVD Circulatory System 0.967 0.706 – 1.32 0.834 38 477 exclusion phecode
415 Pulmonary heart disease Circulatory System 0.959 0.92 – 1 0.0492 2401 31183 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.982 0.721 – 1.34 0.91 44 513 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.927 0.818 – 1.05 0.235 266 4029 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 0.989 0.855 – 1.14 0.881 197 3027 exclusion phecode
416 Cardiomegaly Circulatory System 0.925 0.874 – 0.979 0.0069 1300 17990 exclusion phecode
418 Nonspecific chest pain Circulatory System 0.964 0.949 – 0.978 1.55e-06 18523 198416 exclusion phecode
418.1 Precordial pain Circulatory System 0.946 0.906 – 0.987 0.0109 2284 25880 exclusion phecode
420 Carditis Circulatory System 1 0.946 – 1.06 0.905 1212 14499 exclusion phecode
420.1 Myocarditis Circulatory System 0.857 0.673 – 1.09 0.212 74 906 exclusion phecode
420.2 Pericarditis Circulatory System 1.03 0.953 – 1.1 0.506 783 9266 exclusion phecode
420.21 Acute pericarditis Circulatory System 0.982 0.83 – 1.16 0.834 152 1553 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.01 0.785 – 1.31 0.922 62 736 exclusion phecode
420.3 Endocarditis Circulatory System 0.958 0.865 – 1.06 0.412 400 4851 exclusion phecode
425 Cardiomyopathy Circulatory System 0.941 0.866 – 1.02 0.151 608 8768 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.947 0.871 – 1.03 0.205 596 8515 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.962 0.757 – 1.22 0.753 68 931 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.941 0.759 – 1.17 0.579 89 1171 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 0.882 0.621 – 1.25 0.484 28 403 exclusion phecode
426 Cardiac conduction disorders Circulatory System 0.978 0.946 – 1.01 0.196 3814 46144 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 0.983 0.925 – 1.05 0.591 1125 13826 exclusion phecode
426.21 First degree AV block Circulatory System 0.995 0.91 – 1.09 0.91 527 6397 exclusion phecode
426.23 Second degree AV block Circulatory System 1.01 0.888 – 1.14 0.929 268 2957 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 0.975 0.863 – 1.1 0.687 289 3853 exclusion phecode
426.25 Other heart block Circulatory System 1.06 0.839 – 1.33 0.636 75 868 exclusion phecode
426.3 Bundle branch block Circulatory System 0.96 0.915 – 1.01 0.093 1850 22379 exclusion phecode
426.31 Right bundle branch block Circulatory System 0.975 0.909 – 1.05 0.489 840 10047 exclusion phecode
426.32 Left bundle branch block Circulatory System 0.943 0.883 – 1.01 0.0855 947 11678 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.932 0.795 – 1.09 0.384 163 1747 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 0.926 0.671 – 1.28 0.638 38 404 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.947 0.894 – 1 0.0638 1258 16287 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.952 0.897 – 1.01 0.112 1155 14951 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 0.975 0.958 – 0.992 0.00472 14168 146668 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 0.979 0.935 – 1.03 0.376 1998 22708 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.977 0.927 – 1.03 0.391 1538 16947 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.999 0.911 – 1.1 0.984 501 6314 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 0.974 0.952 – 0.997 0.0268 7861 90141 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.983 0.938 – 1.03 0.475 1921 22082 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.942 0.866 – 1.02 0.162 591 8043 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.964 0.835 – 1.11 0.62 190 2342 exclusion phecode
427.42 Cardiac arrest Circulatory System 0.933 0.85 – 1.02 0.142 476 6663 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.03 0.941 – 1.12 0.562 554 6551 exclusion phecode
427.6 Premature beats Circulatory System 0.939 0.841 – 1.05 0.269 333 3786 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1.03 0.81 – 1.32 0.787 73 831 exclusion phecode
427.7 Tachycardia NOS Circulatory System 0.964 0.911 – 1.02 0.21 1309 15806 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.912 0.8 – 1.04 0.165 247 2726 exclusion phecode
427.9 Palpitations Circulatory System 0.97 0.932 – 1.01 0.129 2672 28419 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.946 0.907 – 0.986 0.00856 2359 36584 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 0.958 0.888 – 1.03 0.263 713 13567 exclusion phecode
428.2 Heart failure NOS Circulatory System 0.94 0.897 – 0.985 0.00902 1894 29081 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 0.933 0.847 – 1.03 0.158 462 5073 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 0.711 0.466 – 1.08 0.113 19 447 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.913 0.815 – 1.02 0.118 336 3689 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 0.978 0.818 – 1.17 0.811 126 1424 exclusion phecode
430 Intracranial hemorrhage Circulatory System 0.989 0.931 – 1.05 0.708 1172 13327 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.01 0.926 – 1.1 0.841 569 6142 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 0.97 0.88 – 1.07 0.542 439 5232 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 0.937 0.793 – 1.11 0.448 150 1749 exclusion phecode
433 Cerebrovascular disease Circulatory System 0.956 0.928 – 0.985 0.00303 4755 58932 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.96 0.883 – 1.04 0.343 603 7600 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 0.927 0.771 – 1.11 0.416 123 1453 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.979 0.937 – 1.02 0.331 2213 28187 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.971 0.906 – 1.04 0.407 850 11261 exclusion phecode
433.3 Cerebral ischemia Circulatory System 0.939 0.892 – 0.988 0.0156 1585 19448 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 0.953 0.898 – 1.01 0.107 1181 14450 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 0.946 0.833 – 1.08 0.397 260 2923 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.89 0.821 – 0.966 0.00511 632 8793 exclusion phecode
440 Atherosclerosis Circulatory System 0.961 0.884 – 1.04 0.352 602 8853 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.963 0.659 – 1.41 0.844 23 734 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.945 0.848 – 1.05 0.303 365 5154 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.05 0.879 – 1.25 0.599 137 1851 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.07 0.954 – 1.2 0.243 315 4192 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1 0.845 – 1.19 0.983 140 1944 exclusion phecode
442 Other aneurysm Circulatory System 0.974 0.908 – 1.04 0.457 871 12071 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.02 0.935 – 1.1 0.714 611 9043 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.01 0.899 – 1.13 0.879 317 5469 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 0.812 0.577 – 1.14 0.233 33 605 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.888 0.713 – 1.11 0.286 87 1106 exclusion phecode
442.4 Arterial dissection Circulatory System 0.804 0.579 – 1.12 0.194 40 411 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 0.919 0.758 – 1.11 0.392 121 1440 exclusion phecode
443 Peripheral vascular disease Circulatory System 0.975 0.931 – 1.02 0.289 1934 26801 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 0.986 0.915 – 1.06 0.719 753 8551 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.904 0.748 – 1.09 0.295 111 2583 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 0.983 0.937 – 1.03 0.471 1857 25181 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.972 0.915 – 1.03 0.362 1122 16871 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 0.895 0.811 – 0.988 0.0281 423 6204 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.852 0.745 – 0.973 0.018 236 3651 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.944 0.852 – 1.05 0.272 395 5738 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.991 0.788 – 1.25 0.94 81 1295 exclusion phecode
446.5 Giant cell arteritis Circulatory System 0.984 0.856 – 1.13 0.826 206 2622 exclusion phecode
446.9 Arteritis NOS Circulatory System 0.949 0.78 – 1.15 0.6 106 1715 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 0.94 0.866 – 1.02 0.142 621 8868 exclusion phecode
447.1 Stricture of artery Circulatory System 0.908 0.82 – 1.01 0.0652 397 5654 exclusion phecode
448 Disease of capillaries Circulatory System 0.882 0.714 – 1.09 0.244 86 1027 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.05 0.943 – 1.16 0.389 381 5156 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.986 0.944 – 1.03 0.515 2252 27957 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.994 0.95 – 1.04 0.783 2088 25960 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 0.985 0.877 – 1.11 0.804 305 4118 exclusion phecode
454 Varicose veins Circulatory System 0.97 0.948 – 0.993 0.01 8006 83774 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 0.968 0.946 – 0.99 0.00506 8287 85950 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.933 0.836 – 1.04 0.217 338 4442 exclusion phecode
455 Hemorrhoids Circulatory System 0.98 0.965 – 0.996 0.0146 16487 171594 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.04 0.835 – 1.29 0.742 85 1265 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.856 0.662 – 1.11 0.24 69 663 exclusion phecode
458 Hypotension Circulatory System 1 0.965 – 1.04 0.964 3122 40224 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.08 1 – 1.17 0.0454 676 8957 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 0.935 0.775 – 1.13 0.481 118 1585 exclusion phecode
458.9 Hypotension NOS Circulatory System 1 0.957 – 1.05 0.903 1883 24554 exclusion phecode
459 Other disorders of circulatory system Circulatory System 0.97 0.949 – 0.991 0.00539 8927 112673 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 0.866 0.688 – 1.09 0.218 74 993 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 0.97 0.949 – 0.991 0.00516 8849 111669 exclusion phecode
464 Acute sinusitis Respiratory 1.03 0.864 – 1.23 0.742 131 1476 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.978 0.928 – 1.03 0.416 1510 16828 exclusion phecode
465.2 Acute pharyngitis Respiratory 1.01 0.93 – 1.11 0.751 553 6196 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.928 0.766 – 1.12 0.443 110 1204 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.981 0.947 – 1.02 0.292 3440 34890 exclusion phecode
471 Nasal polyps Respiratory 0.975 0.935 – 1.02 0.253 2359 23487 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.992 0.917 – 1.07 0.84 694 7120 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 0.989 0.941 – 1.04 0.66 1688 18166 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.06 0.828 – 1.35 0.652 64 747 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.01 0.867 – 1.18 0.883 172 1889 exclusion phecode
473.4 Voice disturbance Respiratory 1.01 0.936 – 1.09 0.795 706 7600 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 0.993 0.939 – 1.05 0.818 1361 14138 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.05 0.951 – 1.16 0.333 426 4455 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.974 0.909 – 1.04 0.464 868 8975 exclusion phecode
475 Chronic sinusitis Respiratory 0.99 0.943 – 1.04 0.682 1842 19122 exclusion phecode
476 Allergic rhinitis Respiratory 1.05 0.975 – 1.13 0.202 804 7930 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 0.948 0.899 – 1 0.0508 1468 16711 exclusion phecode
478 Throat pain Respiratory 1.01 0.889 – 1.15 0.883 269 2775 exclusion phecode
479 Other upper respiratory disease Respiratory 0.967 0.931 – 1.01 0.0893 2863 29922 exclusion phecode
480 Pneumonia Respiratory 0.965 0.939 – 0.991 0.00924 5640 71497 exclusion phecode
480.1 Bacterial pneumonia Respiratory 0.956 0.924 – 0.989 0.00983 3627 46061 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 0.956 0.922 – 0.991 0.014 3210 40833 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 0.844 0.632 – 1.13 0.25 46 634 exclusion phecode
480.2 Viral pneumonia Respiratory 1.04 0.761 – 1.42 0.805 39 522 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.833 0.623 – 1.11 0.218 42 678 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.966 0.875 – 1.07 0.494 423 5257 exclusion phecode
481 Influenza Respiratory 0.972 0.838 – 1.13 0.704 191 2422 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.901 0.747 – 1.09 0.278 116 1405 exclusion phecode
495 Asthma Respiratory 0.98 0.964 – 0.995 0.00993 17338 187928 exclusion phecode
495.2 Asthma with exacerbation Respiratory 0.904 0.771 – 1.06 0.214 164 1912 exclusion phecode
496 Chronic airway obstruction Respiratory 0.953 0.926 – 0.98 0.000707 5308 69214 exclusion phecode
496.1 Emphysema Respiratory 0.942 0.878 – 1.01 0.0937 851 11564 exclusion phecode
496.2 Chronic bronchitis Respiratory 0.961 0.909 – 1.02 0.155 1317 19655 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 0.949 0.895 – 1.01 0.079 1184 17996 exclusion phecode
496.3 Bronchiectasis Respiratory 0.967 0.909 – 1.03 0.294 1112 13006 exclusion phecode
497 Bronchitis Respiratory 0.97 0.87 – 1.08 0.584 345 4518 exclusion phecode
500 Lung disease due to external agents Respiratory 1.05 0.901 – 1.21 0.554 190 2563 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.768 0.551 – 1.07 0.118 37 557 exclusion phecode
500.2 Pneumoconiosis Respiratory 1.17 0.958 – 1.43 0.122 105 1418 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 0.975 0.87 – 1.09 0.67 319 4401 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.04 0.945 – 1.15 0.393 411 6032 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 0.911 0.787 – 1.05 0.212 188 3519 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1 0.851 – 1.18 0.988 142 2260 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 0.803 0.565 – 1.14 0.22 34 435 exclusion phecode
506 Empyema and pneumothorax Respiratory 0.99 0.914 – 1.07 0.808 651 8026 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 0.959 0.927 – 0.993 0.0176 3569 43880 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.916 0.862 – 0.973 0.00469 1123 13891 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.954 0.899 – 1.01 0.124 1185 17527 exclusion phecode
509.1 Respiratory failure Respiratory 0.948 0.886 – 1.01 0.123 923 13859 exclusion phecode
509.2 Respiratory insufficiency Respiratory 0.942 0.876 – 1.01 0.102 807 12198 exclusion phecode
509.5 Respiratory arrest Respiratory 0.991 0.785 – 1.25 0.942 74 1008 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.97 0.835 – 1.13 0.696 184 2579 exclusion phecode
510 Other diseases of lung Respiratory 1.02 0.925 – 1.12 0.707 432 5174 exclusion phecode
512 Other symptoms of respiratory system Respiratory 0.977 0.95 – 1 0.103 5300 64335 exclusion phecode
512.1 Wheezing Respiratory 0.98 0.817 – 1.18 0.826 126 1550 exclusion phecode
512.2 Painful respiration Respiratory 0.954 0.807 – 1.13 0.583 140 1523 exclusion phecode
512.7 Shortness of breath Respiratory 0.965 0.931 – 1 0.048 3323 41531 exclusion phecode
512.8 Cough Respiratory 1.01 0.962 – 1.06 0.67 1711 20522 exclusion phecode
512.9 Other dyspnea Respiratory 0.899 0.823 – 0.982 0.0184 532 6453 exclusion phecode
513 Respiratory abnormalities Respiratory 0.945 0.846 – 1.06 0.316 344 4276 exclusion phecode
513.3 Hypoventilation Respiratory 1.07 0.745 – 1.53 0.723 31 572 exclusion phecode
513.4 Hyperventilation Respiratory 0.911 0.776 – 1.07 0.25 173 2037 exclusion phecode
513.8 Disorders of diaphragm Respiratory 0.946 0.768 – 1.17 0.604 94 1002 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 0.967 0.915 – 1.02 0.232 1360 16815 exclusion phecode
516 Abnormal sputum Respiratory 0.924 0.871 – 0.979 0.00749 1221 14739 exclusion phecode
516.1 Hemoptysis Respiratory 0.937 0.883 – 0.994 0.0298 1196 14347 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.966 0.94 – 0.994 0.0161 5349 66112 exclusion phecode
519.2 Respiratory complications Respiratory 0.888 0.753 – 1.05 0.159 149 2197 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.97 0.942 – 0.998 0.0357 5049 62577 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.02 0.886 – 1.17 0.786 216 2189 exclusion phecode
520 Disorders of tooth development Digestive 0.999 0.948 – 1.05 0.968 1587 16220 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.908 0.659 – 1.25 0.555 33 402 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 1 0.955 – 1.05 0.968 1872 18920 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 0.988 0.944 – 1.03 0.62 1978 22781 exclusion phecode
521.1 Dental caries Digestive 0.988 0.944 – 1.03 0.612 1980 22849 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 0.951 0.898 – 1.01 0.0886 1276 13546 exclusion phecode
522.5 Periapical abscess Digestive 0.956 0.89 – 1.03 0.223 834 8939 exclusion phecode
523 Gingival and periodontal diseases Digestive 0.998 0.94 – 1.06 0.934 1208 12891 exclusion phecode
523.1 Gingivitis Digestive 1.11 0.871 – 1.41 0.405 73 795 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 0.987 0.92 – 1.06 0.711 859 9141 exclusion phecode
523.31 Acute periodontitis Digestive 1.02 0.928 – 1.11 0.72 499 5333 exclusion phecode
523.32 Chronic periodontitis Digestive 1.01 0.916 – 1.12 0.792 405 4296 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.05 0.924 – 1.19 0.464 250 2629 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.04 0.91 – 1.19 0.575 230 2442 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.957 0.911 – 1 0.0738 1776 19685 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.771 0.593 – 1 0.0514 55 521 exclusion phecode
526 Diseases of the jaws Digestive 0.96 0.886 – 1.04 0.313 657 7001 exclusion phecode
526.1 Cysts of the jaws Digestive 0.85 0.742 – 0.974 0.0196 234 2404 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.02 0.754 – 1.38 0.904 49 473 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.01 0.873 – 1.18 0.847 168 1904 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.04 0.891 – 1.21 0.642 164 1846 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 1 0.795 – 1.26 0.985 75 816 exclusion phecode
526.9 Jaw disease NOS Digestive 0.974 0.826 – 1.15 0.754 158 1726 exclusion phecode
527 Diseases of the salivary glands Digestive 0.94 0.853 – 1.04 0.212 455 5107 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.11 0.832 – 1.48 0.482 54 601 exclusion phecode
527.2 Sialoadenitis Digestive 0.939 0.822 – 1.07 0.351 240 2739 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 0.857 0.626 – 1.17 0.337 42 460 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.01 0.81 – 1.25 0.948 84 875 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.976 0.938 – 1.02 0.239 2634 28527 exclusion phecode
528.1 Stomatitis and mucositis Digestive 0.969 0.861 – 1.09 0.597 301 3440 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.948 0.832 – 1.08 0.418 248 2842 exclusion phecode
528.12 Oral aphthae Digestive 1.02 0.777 – 1.34 0.881 56 628 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.997 0.827 – 1.2 0.977 114 1341 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 1.05 0.853 – 1.29 0.644 90 909 exclusion phecode
528.41 Cyst of the salivary gland Digestive 1.19 0.936 – 1.5 0.158 65 703 exclusion phecode
528.5 Diseases of lips Digestive 0.891 0.812 – 0.979 0.0157 474 5001 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 0.995 0.863 – 1.15 0.942 194 2174 exclusion phecode
528.7 Sialolithiasis Digestive 0.991 0.862 – 1.14 0.895 219 2313 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.04 0.969 – 1.12 0.271 829 9018 exclusion phecode
529.1 Glossitis Digestive 1.02 0.884 – 1.18 0.775 186 2166 exclusion phecode
530 Diseases of esophagus Digestive 0.967 0.954 – 0.981 3.83e-06 21728 206908 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.97 0.956 – 0.984 3.22e-05 20403 201209 exclusion phecode
530.11 GERD Digestive 0.975 0.959 – 0.992 0.00321 14956 164974 exclusion phecode
530.12 Ulcer of esophagus Digestive 0.954 0.919 – 0.989 0.0103 3155 35906 exclusion phecode
530.14 Reflux esophagitis Digestive 0.994 0.97 – 1.02 0.648 6827 75648 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.963 0.901 – 1.03 0.269 943 11936 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 0.972 0.915 – 1.03 0.35 1178 12933 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.09 0.981 – 1.21 0.111 399 4577 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.972 0.789 – 1.2 0.786 101 1024 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.93 0.808 – 1.07 0.308 215 2522 exclusion phecode
530.9 Heartburn Digestive 1.02 0.965 – 1.07 0.517 1495 15580 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.948 0.919 – 0.978 0.000908 4226 49668 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.941 0.844 – 1.05 0.272 352 4319 exclusion phecode
531.2 Gastric ulcer Digestive 0.936 0.898 – 0.976 0.00176 2423 28820 exclusion phecode
531.3 Duodenal ulcer Digestive 0.941 0.897 – 0.987 0.0135 1799 20881 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 0.985 0.865 – 1.12 0.82 239 2939 exclusion phecode
532 Dysphagia Digestive 0.953 0.923 – 0.984 0.00277 4228 46637 exclusion phecode
535 Gastritis and duodenitis Digestive 0.977 0.962 – 0.992 0.00304 18173 191285 exclusion phecode
535.1 Acute gastritis Digestive 0.958 0.887 – 1.04 0.278 717 8385 exclusion phecode
535.2 Atrophic gastritis Digestive 1.04 0.913 – 1.2 0.526 234 2533 exclusion phecode
535.6 Duodenitis Digestive 0.983 0.954 – 1.01 0.277 4682 54128 exclusion phecode
535.8 Other specified gastritis Digestive 0.98 0.952 – 1.01 0.165 5239 57860 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.03 0.829 – 1.29 0.773 83 858 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.01 0.861 – 1.17 0.947 175 1868 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 0.968 0.925 – 1.01 0.16 2045 24138 exclusion phecode
540 Appendiceal conditions Digestive 1.01 0.968 – 1.06 0.634 2266 23459 exclusion phecode
540.1 Appendicitis Digestive 1.01 0.967 – 1.06 0.632 2134 21972 exclusion phecode
540.11 Acute appendicitis Digestive 1.04 0.989 – 1.09 0.129 1944 19778 exclusion phecode
550 Abdominal hernia Digestive 0.965 0.953 – 0.977 1.3e-08 29510 211276 exclusion phecode
550.1 Inguinal hernia Digestive 0.958 0.939 – 0.978 3.51e-05 10584 84628 exclusion phecode
550.2 Diaphragmatic hernia Digestive 0.962 0.947 – 0.978 1.88e-06 16946 174899 exclusion phecode
550.3 Femoral hernia Digestive 0.936 0.853 – 1.03 0.165 492 4835 exclusion phecode
550.4 Umbilical hernia Digestive 0.975 0.933 – 1.02 0.25 2206 26237 exclusion phecode
550.5 Ventral hernia Digestive 0.975 0.932 – 1.02 0.282 2061 24752 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 0.931 0.896 – 0.967 0.000211 2931 33097 exclusion phecode
555.1 Regional enteritis Digestive 0.949 0.893 – 1.01 0.0966 1107 13156 exclusion phecode
555.2 Ulcerative colitis Digestive 0.939 0.899 – 0.982 0.00599 2119 23491 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 0.953 0.858 – 1.06 0.372 381 4097 exclusion phecode
556 Ulceration of the lower GI tract Digestive 0.928 0.858 – 1 0.0589 693 7778 exclusion phecode
556.1 Ulceration of intestine Digestive 0.911 0.825 – 1.01 0.0667 429 4916 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.04 0.899 – 1.2 0.597 198 2289 exclusion phecode
557.1 Celiac disease Digestive 1.18 1.11 – 1.25 1.51e-08 1289 13848 exclusion phecode
558 Noninfectious gastroenteritis Digestive 0.979 0.959 – 0.999 0.0401 10139 116051 exclusion phecode
559 Ileostomy status Digestive 0.983 0.921 – 1.05 0.614 998 11716 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 0.968 0.929 – 1.01 0.117 2534 28294 exclusion phecode
560.1 Paralytic ileus Digestive 0.978 0.872 – 1.1 0.706 318 3637 exclusion phecode
560.2 Impaction of intestine Digestive 0.943 0.805 – 1.1 0.462 165 1951 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.952 0.872 – 1.04 0.27 547 6023 exclusion phecode
560.4 Other intestinal obstruction Digestive 0.969 0.928 – 1.01 0.166 2181 24215 exclusion phecode
561 Symptoms involving digestive system Digestive 0.989 0.97 – 1.01 0.284 11071 118093 exclusion phecode
561.1 Diarrhea Digestive 1.04 0.929 – 1.17 0.485 307 3348 exclusion phecode
561.2 Flatulence Digestive 0.94 0.886 – 0.997 0.0407 1188 12682 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 0.965 0.95 – 0.98 1.15e-05 17018 154122 exclusion phecode
562.1 Diverticulosis Digestive 0.965 0.949 – 0.98 9.93e-06 16988 154070 exclusion phecode
563 Constipation Digestive 0.972 0.949 – 0.997 0.0282 6720 75745 exclusion phecode
564 Functional digestive disorders Digestive 0.964 0.947 – 0.981 2.78e-05 14222 154657 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 0.99 0.958 – 1.02 0.526 4007 42741 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 0.989 0.928 – 1.05 0.727 1036 11923 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 0.948 0.929 – 0.968 6.53e-07 9638 108537 exclusion phecode
565 Anal and rectal conditions Digestive 0.983 0.963 – 1 0.101 10014 106323 exclusion phecode
565.1 Anal and rectal polyp Digestive 0.98 0.951 – 1.01 0.173 4897 51529 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 0.979 0.895 – 1.07 0.647 519 6610 exclusion phecode
568 Other disorders of peritoneum Digestive 0.938 0.897 – 0.98 0.00417 2143 24137 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.942 0.901 – 0.986 0.0101 2045 22970 exclusion phecode
569 Other disorders of intestine Digestive 0.974 0.936 – 1.01 0.191 2686 29901 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.12 0.912 – 1.37 0.282 94 1003 exclusion phecode
569.2 Gastrointestinal complications Digestive 0.928 0.827 – 1.04 0.206 318 3425 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 0.97 0.921 – 1.02 0.257 1504 21458 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 0.984 0.921 – 1.05 0.63 944 12403 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.1 0.849 – 1.43 0.461 55 810 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 0.989 0.817 – 1.2 0.908 105 1910 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.968 0.879 – 1.07 0.509 430 6942 exclusion phecode
571.81 Portal hypertension Digestive 0.853 0.744 – 0.979 0.0232 214 3717 exclusion phecode
572 Ascites (non malignant) Digestive 0.952 0.888 – 1.02 0.162 870 11009 exclusion phecode
573 Other disorders of liver Digestive 0.955 0.89 – 1.02 0.191 842 10720 exclusion phecode
573.2 Liver replaced by transplant Digestive 0.842 0.529 – 1.34 0.467 15 719 exclusion phecode
573.3 Hepatomegaly Digestive 0.909 0.77 – 1.07 0.262 145 2103 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 0.975 0.89 – 1.07 0.593 498 6264 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 0.995 0.951 – 1.04 0.845 2045 24822 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.12 0.939 – 1.34 0.205 118 1416 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 0.942 0.923 – 0.962 1.35e-08 9995 116039 exclusion phecode
574.1 Cholelithiasis Digestive 0.947 0.926 – 0.968 1.07e-06 8674 100916 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.953 0.89 – 1.02 0.16 915 10927 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.943 0.911 – 0.976 0.000829 3535 40608 exclusion phecode
574.2 Calculus of bile duct Digestive 0.948 0.901 – 0.997 0.0393 1591 19218 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.896 0.852 – 0.942 1.63e-05 1684 20184 exclusion phecode
575 Other biliary tract disease Digestive 0.981 0.941 – 1.02 0.361 2417 28197 exclusion phecode
575.1 Cholangitis Digestive 1.09 0.955 – 1.24 0.21 246 3359 exclusion phecode
575.2 Obstruction of bile duct Digestive 0.979 0.891 – 1.08 0.659 469 5513 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 1.01 0.904 – 1.13 0.862 329 3555 exclusion phecode
575.7 Other disorders of gallbladder Digestive 0.969 0.906 – 1.04 0.358 903 10419 exclusion phecode
575.8 Other disorders of biliary tract Digestive 0.909 0.837 – 0.987 0.0236 629 7533 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.952 0.827 – 1.1 0.489 201 2448 exclusion phecode
577 Diseases of pancreas Digestive 0.983 0.933 – 1.04 0.522 1539 18975 exclusion phecode
577.1 Acute pancreatitis Digestive 0.999 0.94 – 1.06 0.967 1156 14294 exclusion phecode
577.2 Chronic pancreatitis Digestive 1.03 0.918 – 1.16 0.585 289 3652 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.05 0.916 – 1.21 0.466 214 2618 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 0.967 0.95 – 0.984 0.000162 14019 150844 exclusion phecode
578.1 Hematemesis Digestive 1.01 0.945 – 1.07 0.869 1103 13997 exclusion phecode
578.2 Blood in stool Digestive 0.955 0.907 – 1.01 0.0795 1574 18437 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 0.966 0.945 – 0.987 0.00162 9164 96331 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.974 0.941 – 1.01 0.128 3559 38564 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.988 0.923 – 1.06 0.723 915 11399 exclusion phecode
579.2 Splenomegaly Digestive 1.02 0.872 – 1.2 0.796 164 2991 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.942 0.887 – 1 0.0573 1127 11968 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.1 0.981 – 1.22 0.105 320 10528 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.2 1.04 – 1.38 0.0137 189 7088 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.747 0.485 – 1.15 0.185 18 560 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.995 0.717 – 1.38 0.975 37 957 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.33 1.12 – 1.56 0.000855 140 5813 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1 0.832 – 1.21 0.973 113 3276 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.943 0.74 – 1.2 0.639 66 1741 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.946 0.743 – 1.21 0.655 67 1798 exclusion phecode
585 Renal failure Genitourinary 1.04 0.998 – 1.09 0.0604 2224 47440 exclusion phecode
585.1 Acute renal failure Genitourinary 1.02 0.972 – 1.07 0.388 1647 30586 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.06 0.965 – 1.18 0.213 407 10013 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.12 1.02 – 1.23 0.0212 445 17878 exclusion phecode
585.31 Renal dialysis Genitourinary 1.01 0.793 – 1.28 0.947 67 3525 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 0.943 0.897 – 0.992 0.0238 1613 23513 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.857 0.63 – 1.16 0.324 46 1460 exclusion phecode
586.11 Small kidney Genitourinary 0.999 0.716 – 1.39 0.996 38 1242 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 0.943 0.871 – 1.02 0.148 653 8642 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.843 0.586 – 1.21 0.357 26 569 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.876 0.798 – 0.963 0.00609 473 6532 exclusion phecode
587 Kidney replaced by transpant Genitourinary 0.956 0.666 – 1.37 0.807 24 2697 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 0.733 0.489 – 1.1 0.133 21 735 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.07 0.795 – 1.45 0.645 42 808 exclusion phecode
590 Pyelonephritis Genitourinary 0.986 0.917 – 1.06 0.702 801 10146 exclusion phecode
591 Urinary tract infection Genitourinary 0.971 0.948 – 0.994 0.0144 7516 88690 exclusion phecode
592 Cystitis and urethritis Genitourinary 0.989 0.944 – 1.04 0.646 1928 21171 exclusion phecode
592.1 Cystitis Genitourinary 0.978 0.932 – 1.02 0.345 1886 20769 exclusion phecode
592.11 Acute cystitis Genitourinary 1.1 0.882 – 1.38 0.394 86 944 exclusion phecode
592.12 Chronic cystitis Genitourinary 0.99 0.909 – 1.08 0.821 577 6386 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.16 0.991 – 1.35 0.0654 173 1820 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.09 0.904 – 1.31 0.367 121 1186 exclusion phecode
593 Hematuria Genitourinary 0.941 0.922 – 0.96 3.83e-09 10355 112993 exclusion phecode
594 Urinary calculus Genitourinary 0.874 0.845 – 0.903 8.39e-16 3976 45158 exclusion phecode
594.1 Calculus of kidney Genitourinary 0.825 0.786 – 0.865 1.76e-15 1936 22297 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 0.952 0.863 – 1.05 0.332 430 5060 exclusion phecode
594.3 Calculus of ureter Genitourinary 0.887 0.84 – 0.936 1.39e-05 1479 17012 exclusion phecode
594.8 Renal colic Genitourinary 0.883 0.835 – 0.934 1.39e-05 1333 14789 exclusion phecode
595 Hydronephrosis Genitourinary 0.907 0.852 – 0.965 0.00223 1061 13692 exclusion phecode
596 Other disorders of bladder Genitourinary 0.97 0.945 – 0.996 0.0232 6147 66514 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 0.961 0.906 – 1.02 0.196 1187 12461 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1 0.94 – 1.06 0.99 1093 12035 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.955 0.917 – 0.995 0.0273 2569 27514 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.952 0.911 – 0.995 0.0293 2151 23144 exclusion phecode
597.2 Urinary complications NEC Genitourinary 0.952 0.683 – 1.33 0.771 38 544 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 0.971 0.93 – 1.01 0.19 2262 24317 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.866 0.735 – 1.02 0.0862 158 2095 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.97 0.952 – 0.988 0.00123 12379 133880 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.88 0.699 – 1.11 0.275 79 1139 exclusion phecode
599.2 Retention of urine Genitourinary 0.978 0.947 – 1.01 0.187 3915 44012 exclusion phecode
599.3 Dysuria Genitourinary 0.972 0.903 – 1.05 0.442 767 8611 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.969 0.944 – 0.995 0.0193 6225 66676 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 0.961 0.924 – 1 0.0535 2659 28363 exclusion phecode
599.6 Oliguria and anuria Genitourinary 0.924 0.669 – 1.28 0.633 37 695 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 0.76 0.548 – 1.05 0.0986 37 432 exclusion phecode
599.9 Other abnormality of urination Genitourinary 0.952 0.898 – 1.01 0.0997 1246 13115 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.973 0.948 – 0.999 0.039 6386 55946 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 0.936 0.883 – 0.992 0.025 1239 13404 exclusion phecode
601.1 Prostatitis Genitourinary 0.939 0.878 – 1 0.0631 935 9926 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.849 0.711 – 1.01 0.0689 135 1527 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1 0.919 – 1.1 0.943 548 5689 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.894 0.666 – 1.2 0.459 45 421 exclusion phecode
601.4 Balanoposthitis Genitourinary 0.956 0.821 – 1.11 0.563 179 1907 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.971 0.831 – 1.13 0.71 168 2013 exclusion phecode
602 Other disorders of prostate Genitourinary 0.938 0.872 – 1.01 0.0835 787 8223 exclusion phecode
603 Other disorders of testis Genitourinary 1.01 0.951 – 1.06 0.826 1349 14624 exclusion phecode
603.1 Hydrocele Genitourinary 1.07 0.994 – 1.15 0.0714 832 8911 exclusion phecode
604 Disorders of penis Genitourinary 0.987 0.943 – 1.03 0.564 2065 22593 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.996 0.948 – 1.05 0.886 1692 18724 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.959 0.82 – 1.12 0.604 168 1816 exclusion phecode
608 Other disorders of male genital organs Genitourinary 0.983 0.936 – 1.03 0.496 1823 19075 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.822 0.686 – 0.985 0.0341 135 1361 exclusion phecode
609.1 Infertility, male Genitourinary 0.718 0.524 – 0.982 0.0381 49 503 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.801 0.647 – 0.991 0.0407 99 1002 exclusion phecode
610 Benign mammary dysplasias Genitourinary 1.02 0.97 – 1.06 0.517 1972 19921 exclusion phecode
610.1 Cystic mastopathy Genitourinary 1.02 0.943 – 1.1 0.661 722 7285 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1.03 0.902 – 1.17 0.697 238 2420 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 0.95 0.834 – 1.08 0.446 235 2364 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 1.03 0.966 – 1.09 0.386 1121 11242 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.973 0.891 – 1.06 0.552 522 5394 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.994 0.937 – 1.05 0.846 1239 12358 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.799 0.59 – 1.08 0.147 48 428 exclusion phecode
611.3 Lump or mass in breast Genitourinary 1 0.943 – 1.06 0.967 1195 11952 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1 0.926 – 1.08 0.959 675 7059 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1 0.921 – 1.09 0.998 644 6692 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 1.02 0.785 – 1.34 0.863 62 597 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.972 0.916 – 1.03 0.343 1213 13058 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 0.99 0.906 – 1.08 0.83 519 5681 exclusion phecode
613.5 Mastodynia Genitourinary 0.901 0.675 – 1.2 0.476 52 617 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.933 0.853 – 1.02 0.125 543 5480 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 0.939 0.826 – 1.07 0.336 252 2598 exclusion phecode
613.9 Breast disorder NOS Genitourinary – 154 1613 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.956 0.927 – 0.985 0.00352 4555 46930 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.926 0.884 – 0.969 0.000861 2029 21054 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.952 0.879 – 1.03 0.224 674 6917 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.964 0.726 – 1.28 0.799 50 511 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.924 0.827 – 1.03 0.165 335 3472 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.02 0.903 – 1.15 0.747 284 2951 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.01 0.88 – 1.16 0.898 219 2266 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.989 0.945 – 1.03 0.618 2070 21159 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.977 0.916 – 1.04 0.468 1039 10678 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.05 0.938 – 1.17 0.413 334 3428 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.945 0.872 – 1.02 0.164 632 6251 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.917 0.793 – 1.06 0.241 205 2238 exclusion phecode
615 Endometriosis Genitourinary 0.975 0.94 – 1.01 0.159 3310 33907 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 0.955 0.83 – 1.1 0.516 222 2413 exclusion phecode
618 Genital prolapse Genitourinary 0.956 0.935 – 0.977 5.66e-05 8798 89103 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.953 0.927 – 0.98 0.000786 5502 56218 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.956 0.926 – 0.987 0.00595 4144 40977 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.06 0.953 – 1.18 0.282 373 3802 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.96 0.873 – 1.06 0.395 475 5087 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 0.981 0.957 – 1.01 0.122 6911 70025 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.937 0.86 – 1.02 0.142 582 5971 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 0.978 0.94 – 1.02 0.285 2576 26151 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.02 0.974 – 1.06 0.445 2316 23245 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.96 0.909 – 1.01 0.147 1403 14196 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.992 0.931 – 1.06 0.794 1065 10872 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 0.882 0.672 – 1.16 0.367 51 574 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.983 0.914 – 1.06 0.635 819 8975 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.989 0.966 – 1.01 0.329 8117 82727 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.998 0.972 – 1.02 0.878 5988 62113 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 1 0.963 – 1.04 0.953 2767 26862 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 0.979 0.917 – 1.04 0.512 1009 10437 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 1.05 0.964 – 1.14 0.268 582 6032 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 1.06 0.911 – 1.24 0.446 171 1815 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 0.997 0.89 – 1.12 0.964 320 3333 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.98 0.95 – 1.01 0.197 4407 45979 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.03 0.992 – 1.08 0.119 2427 24139 exclusion phecode
625.1 Dyspareunia Genitourinary 1.03 0.966 – 1.1 0.364 990 9975 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.994 0.977 – 1.01 0.548 13511 95319 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.996 0.977 – 1.02 0.667 11804 91590 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 1.09 0.879 – 1.36 0.421 86 937 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 0.99 0.968 – 1.01 0.395 8024 77074 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.992 0.943 – 1.04 0.771 1612 16218 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.994 0.958 – 1.03 0.739 3186 32196 exclusion phecode
626.2 Dysmenorrhea Genitourinary 1.03 0.979 – 1.09 0.235 1464 15245 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.972 0.807 – 1.17 0.768 119 1378 exclusion phecode
626.8 Infertility, female Genitourinary 0.967 0.913 – 1.03 0.265 1228 12044 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.964 0.942 – 0.987 0.00251 7565 79145 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 0.97 0.945 – 0.995 0.0175 6532 68560 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.945 0.794 – 1.12 0.523 136 1443 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.987 0.918 – 1.06 0.728 797 8226 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 0.899 0.788 – 1.03 0.115 241 2526 exclusion phecode
628 Ovarian cyst Genitourinary 0.972 0.94 – 1 0.0956 3823 39143 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.993 0.963 – 1.02 0.658 4734 32491 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.04 0.972 – 1.1 0.28 1022 10166 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.04 0.926 – 1.17 0.493 301 2930 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.981 0.935 – 1.03 0.432 1817 15648 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.949 0.883 – 1.02 0.152 798 7773 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1 0.944 – 1.06 0.956 1167 11078 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.02 0.973 – 1.06 0.446 2145 17938 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 1.02 0.939 – 1.12 0.6 563 5515 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.02 0.959 – 1.09 0.483 985 9563 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 0.957 0.735 – 1.24 0.741 61 625 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.95 0.89 – 1.01 0.117 981 10029 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.865 0.763 – 0.98 0.0225 271 2751 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.874 0.75 – 1.02 0.0855 185 1948 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.907 0.757 – 1.09 0.288 131 1363 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.97 0.913 – 1.03 0.316 1147 11281 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.02 0.976 – 1.07 0.351 2016 18854 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.847 0.65 – 1.1 0.22 59 600 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.03 0.909 – 1.17 0.624 258 2476 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.01 0.82 – 1.24 0.951 103 1010 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.07 0.919 – 1.24 0.397 176 1744 exclusion phecode
650 Normal delivery Pregnancy Complications 1.02 0.971 – 1.07 0.446 1772 17119 exclusion phecode
651 Multiple gestation Pregnancy Complications 0.986 0.878 – 1.11 0.81 310 3126 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1 0.953 – 1.06 0.91 1590 14954 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.945 0.892 – 1 0.0537 1281 12312 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.1 0.854 – 1.43 0.449 66 656 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.01 0.979 – 1.05 0.485 3940 26537 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.912 0.743 – 1.12 0.381 95 977 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 1.01 0.962 – 1.05 0.781 2086 16594 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.992 0.905 – 1.09 0.86 492 4803 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 1.01 0.984 – 1.05 0.361 4864 26481 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.975 0.934 – 1.02 0.241 2333 19087 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.967 0.816 – 1.14 0.692 146 1472 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.968 0.851 – 1.1 0.626 241 2368 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.929 0.713 – 1.21 0.586 58 565 exclusion phecode
679 Complications of in utero procedures Dermatologic 1.17 0.874 – 1.56 0.295 48 490 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 0.989 0.958 – 1.02 0.512 4027 51507 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.988 0.888 – 1.1 0.827 353 4109 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.94 0.842 – 1.05 0.27 346 3838 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.99 0.953 – 1.03 0.596 2928 38974 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.988 0.952 – 1.03 0.545 2932 39017 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.993 0.956 – 1.03 0.71 2904 38675 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 0.903 0.811 – 1 0.0601 358 4375 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 0.992 0.924 – 1.07 0.826 807 9636 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 0.888 0.842 – 0.936 1.15e-05 1475 17138 exclusion phecode
686.3 Pilonidal cyst Dermatologic 0.906 0.818 – 1 0.06 404 4550 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.04 0.912 – 1.18 0.587 255 2627 exclusion phecode
687 Symptoms affecting skin Dermatologic 0.937 0.839 – 1.05 0.245 351 3979 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.997 0.942 – 1.06 0.927 1288 15623 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.08 0.934 – 1.25 0.301 195 2039 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.784 0.611 – 1.01 0.0567 71 794 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 0.98 0.936 – 1.03 0.401 1962 21730 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.945 0.914 – 0.976 0.000593 3950 41432 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.833 0.617 – 1.12 0.232 46 529 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.827 0.596 – 1.15 0.256 36 386 exclusion phecode
691 Congenital anomalies of skin Dermatologic 1.09 0.87 – 1.37 0.449 80 876 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.945 0.876 – 1.02 0.143 723 7202 exclusion phecode
694.1 Vitiligo Dermatologic 0.946 0.694 – 1.29 0.728 39 445 exclusion phecode
694.2 Other dyschromia Dermatologic 0.979 0.901 – 1.06 0.615 597 5704 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 0.776 0.605 – 0.996 0.0463 68 847 exclusion phecode
695 Erythematous conditions Dermatologic 0.927 0.879 – 0.977 0.00481 1513 17392 exclusion phecode
695.1 Toxic erythema Dermatologic 0.953 0.747 – 1.22 0.699 66 829 exclusion phecode
695.2 Bullous dermatoses Dermatologic 0.855 0.687 – 1.07 0.163 87 966 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 0.947 0.682 – 1.32 0.746 36 395 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.781 0.582 – 1.05 0.1 48 516 exclusion phecode
695.3 Rosacea Dermatologic 0.83 0.721 – 0.956 0.00982 224 2212 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 0.779 0.678 – 0.894 0.000394 219 3148 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.79 0.622 – 1 0.0534 71 955 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 0.751 0.644 – 0.876 0.000269 179 2643 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 1.03 0.944 – 1.13 0.483 527 5652 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 0.913 0.775 – 1.08 0.277 146 1752 exclusion phecode
695.81 Erythema nodosum Dermatologic 1.13 0.866 – 1.49 0.36 55 604 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 0.968 0.857 – 1.09 0.604 280 3288 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.97 0.917 – 1.03 0.282 1320 16391 exclusion phecode
696.4 Psoriasis Dermatologic 0.966 0.913 – 1.02 0.236 1285 16044 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.96 0.899 – 1.03 0.232 954 12132 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.953 0.866 – 1.05 0.331 450 5291 exclusion phecode
697 Sarcoidosis Dermatologic 1.01 0.892 – 1.14 0.875 268 4024 exclusion phecode
698 Pruritus and related conditions Dermatologic 0.938 0.86 – 1.02 0.145 550 5719 exclusion phecode
700 Corns and callosities Dermatologic 0.949 0.815 – 1.1 0.498 185 2154 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.986 0.951 – 1.02 0.446 3312 34327 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.973 0.736 – 1.29 0.846 54 590 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.986 0.938 – 1.04 0.584 1716 17453 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.982 0.725 – 1.33 0.907 38 428 exclusion phecode
701.4 Keloid scar Dermatologic 0.963 0.824 – 1.13 0.639 162 1675 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 0.972 0.867 – 1.09 0.623 338 3396 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 0.828 0.649 – 1.06 0.131 64 767 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.02 0.983 – 1.05 0.352 3821 38063 exclusion phecode
702.1 Actinic keratosis Dermatologic 1.03 0.977 – 1.08 0.301 1753 17669 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 1.01 0.965 – 1.05 0.713 2208 21594 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.01 0.884 – 1.15 0.895 230 2525 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.992 0.914 – 1.08 0.849 620 7152 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.951 0.92 – 0.983 0.00308 3837 39206 exclusion phecode
704.1 Alopecia Dermatologic 0.892 0.72 – 1.1 0.293 83 992 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.03 0.785 – 1.36 0.822 58 561 exclusion phecode
705 Disorders of sweat glands Dermatologic 0.947 0.798 – 1.12 0.538 139 1822 exclusion phecode
705.3 Hidradenitis Dermatologic 0.917 0.757 – 1.11 0.373 114 1494 exclusion phecode
705.8 Hyperhidrosis Dermatologic 0.887 0.797 – 0.988 0.0285 361 4228 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 0.97 0.944 – 0.996 0.022 6063 61421 exclusion phecode
706.1 Acne Dermatologic 0.718 0.545 – 0.946 0.0185 57 622 exclusion phecode
706.2 Sebaceous cyst Dermatologic 0.972 0.947 – 0.997 0.0286 6421 64821 exclusion phecode
707 Chronic ulcer of skin Dermatologic 0.92 0.858 – 0.987 0.0208 823 13259 exclusion phecode
707.1 Decubitus ulcer Dermatologic 0.91 0.825 – 1 0.059 426 6025 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 1.01 0.963 – 1.05 0.796 2182 24985 exclusion phecode
709.2 Sicca syndrome Dermatologic 0.92 0.811 – 1.04 0.19 260 3817 exclusion phecode
709.3 Systemic sclerosis Dermatologic 0.943 0.764 – 1.16 0.583 90 1293 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.748 0.527 – 1.06 0.103 32 505 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.01 0.964 – 1.06 0.648 1812 19648 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.913 0.811 – 1.03 0.138 290 4237 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 0.905 0.799 – 1.03 0.117 266 3944 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.894 0.731 – 1.09 0.277 99 1413 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.909 0.781 – 1.06 0.221 176 2796 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 0.997 0.875 – 1.14 0.962 246 3048 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.06 0.914 – 1.24 0.428 183 2351 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.13 0.838 – 1.52 0.426 46 569 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.07 0.829 – 1.37 0.62 65 1078 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.06 0.646 – 1.75 0.81 15 445 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.954 0.917 – 0.992 0.0188 2698 35492 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.957 0.918 – 0.998 0.039 2421 32196 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.973 0.913 – 1.04 0.392 1023 12060 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.812 0.646 – 1.02 0.0726 72 897 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.935 0.843 – 1.04 0.208 379 4404 exclusion phecode
716 Other arthropathies Musculoskeletal 0.972 0.959 – 0.985 4.74e-05 23477 196989 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.925 0.884 – 0.967 0.000626 2074 25167 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.965 0.945 – 0.986 0.000939 9596 111168 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 0.975 0.961 – 0.988 0.000291 22494 194363 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.963 0.885 – 1.05 0.378 598 7700 exclusion phecode
720 Spinal stenosis Musculoskeletal 1 0.959 – 1.05 0.933 2203 25800 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 0.944 0.917 – 0.972 0.000136 4838 55921 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.942 0.908 – 0.978 0.00154 3110 35929 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.03 0.849 – 1.25 0.753 109 1333 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 1.08 0.939 – 1.24 0.284 211 2495 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 0.982 0.957 – 1.01 0.182 6074 66959 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.06 0.957 – 1.18 0.258 377 3878 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.01 0.967 – 1.06 0.569 1811 21082 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.05 0.791 – 1.4 0.726 47 524 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1 0.967 – 1.04 0.838 2998 32921 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.07 0.952 – 1.2 0.263 335 3762 exclusion phecode
723.1 Torticollis Musculoskeletal 1 0.796 – 1.26 0.983 79 818 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.02 0.961 – 1.07 0.582 1386 15228 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1.01 0.9 – 1.13 0.854 307 3198 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.994 0.886 – 1.11 0.912 311 3212 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.16 0.849 – 1.59 0.348 39 439 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.01 0.951 – 1.08 0.699 1061 11786 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1 0.982 – 1.02 0.798 10176 107805 exclusion phecode
726.1 Enthesopathy Musculoskeletal 1 0.978 – 1.03 0.783 6550 69785 exclusion phecode
726.2 Synoviopathy Musculoskeletal 1 0.884 – 1.14 0.954 266 2591 exclusion phecode
726.3 Bursitis Musculoskeletal 1.01 0.924 – 1.1 0.868 564 6223 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.977 0.95 – 1.01 0.111 5229 54739 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.975 0.93 – 1.02 0.305 1873 20440 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 1.05 0.83 – 1.33 0.682 77 733 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.976 0.935 – 1.02 0.252 2325 23560 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 1.02 0.918 – 1.14 0.704 375 4137 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.07 0.933 – 1.23 0.332 242 2529 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.865 0.702 – 1.07 0.177 99 1022 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.04 1 – 1.09 0.0459 2465 24188 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.01 0.894 – 1.13 0.93 308 3266 exclusion phecode
728.7 Fasciitis Musculoskeletal 1.04 1 – 1.09 0.0447 2559 25266 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.04 1 – 1.09 0.0508 2348 22728 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 0.994 0.961 – 1.03 0.726 3620 44027 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.91 0.839 – 0.987 0.0221 655 7817 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.849 0.673 – 1.07 0.167 77 746 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.85 0.733 – 0.986 0.0319 196 2119 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.816 0.701 – 0.95 0.00899 186 2012 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.936 0.839 – 1.05 0.244 344 3573 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.881 0.744 – 1.04 0.142 145 1541 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.835 0.601 – 1.16 0.284 43 451 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.925 0.871 – 0.981 0.00953 1196 13157 exclusion phecode
733.2 Cyst of bone Musculoskeletal 0.991 0.862 – 1.14 0.893 225 2302 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.904 0.805 – 1.02 0.0889 316 3935 exclusion phecode
733.6 Costochondritis Musculoskeletal 1.15 0.919 – 1.45 0.221 85 939 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.02 0.947 – 1.09 0.631 820 9217 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.16 0.931 – 1.44 0.187 93 930 exclusion phecode
735 Acquired foot deformities Musculoskeletal 0.992 0.967 – 1.02 0.499 6982 71984 exclusion phecode
735.1 Flat foot Musculoskeletal 0.857 0.715 – 1.03 0.0946 122 1423 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 0.978 0.945 – 1.01 0.21 3551 37254 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.982 0.928 – 1.04 0.519 1329 14089 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.979 0.92 – 1.04 0.489 1142 11378 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.993 0.964 – 1.02 0.629 4947 50311 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 0.948 0.888 – 1.01 0.102 1006 11671 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 0.958 0.818 – 1.12 0.591 171 1820 exclusion phecode
737 Curvature of spine Musculoskeletal 0.994 0.919 – 1.08 0.883 691 8211 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.983 0.906 – 1.07 0.682 649 7702 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.979 0.924 – 1.04 0.481 1249 13821 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1 0.936 – 1.07 0.995 955 10770 exclusion phecode
739 Contracture of joint Musculoskeletal 0.963 0.856 – 1.08 0.538 306 3667 exclusion phecode
740 Osteoarthrosis Musculoskeletal 0.965 0.95 – 0.98 8.23e-06 17376 166682 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.972 0.953 – 0.991 0.00461 11040 119049 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.982 0.955 – 1.01 0.191 5522 62406 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.93 0.812 – 1.06 0.288 227 2490 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.963 0.863 – 1.07 0.495 343 4215 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.958 0.936 – 0.981 0.000394 7456 87250 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.975 0.934 – 1.02 0.237 2324 25926 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.979 0.764 – 1.25 0.865 68 725 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 0.987 0.895 – 1.09 0.785 450 4582 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.922 0.729 – 1.17 0.497 79 1092 exclusion phecode
741.4 Joint effusions Musculoskeletal 0.954 0.889 – 1.02 0.19 843 10050 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.18 0.919 – 1.51 0.197 68 795 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 1.08 0.77 – 1.51 0.66 37 413 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.994 0.949 – 1.04 0.786 2079 21769 exclusion phecode
742.1 Loose body in joint Musculoskeletal 0.973 0.852 – 1.11 0.69 236 2417 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.15 0.899 – 1.47 0.266 75 790 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 0.904 0.809 – 1.01 0.0714 350 3839 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 1.02 0.97 – 1.08 0.396 1489 15364 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.951 0.923 – 0.979 0.000704 4923 54050 exclusion phecode
743.1 Osteoporosis Musculoskeletal 0.946 0.917 – 0.977 0.00069 4147 45488 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 0.943 0.911 – 0.976 0.000752 3611 39824 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 0.878 0.783 – 0.984 0.0247 319 3471 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 0.948 0.84 – 1.07 0.382 281 3692 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.986 0.907 – 1.07 0.749 583 6068 exclusion phecode
745 Pain in joint Musculoskeletal 0.959 0.932 – 0.987 0.00423 5204 58798 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.02 0.97 – 1.07 0.435 1632 19231 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.02 0.964 – 1.07 0.551 1509 17983 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1.09 0.981 – 1.21 0.111 413 4430 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.987 0.837 – 1.16 0.876 152 1731 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.986 0.922 – 1.05 0.675 929 11802 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.12 0.925 – 1.35 0.248 116 1230 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.1 0.778 – 1.54 0.601 35 360 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.88 0.767 – 1.01 0.0704 226 2300 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 1.1 0.995 – 1.21 0.0631 420 4857 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.07 0.933 – 1.24 0.32 206 2222 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.03 0.857 – 1.23 0.77 122 1296 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.09 0.951 – 1.26 0.208 210 2597 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.21 1.03 – 1.42 0.0233 158 1622 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.898 0.672 – 1.2 0.466 46 877 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.924 0.864 – 0.989 0.0231 905 11418 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.96 0.879 – 1.05 0.37 537 5406 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1 0.901 – 1.11 0.996 372 3782 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.977 0.825 – 1.16 0.788 155 1519 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.862 0.776 – 0.956 0.00515 370 6043 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.78 0.656 – 0.928 0.00509 133 3003 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.896 0.772 – 1.04 0.145 186 2457 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.07 0.941 – 1.23 0.291 231 2580 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.02 0.876 – 1.18 0.818 180 2025 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.977 0.828 – 1.15 0.782 145 1665 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.32 1 – 1.75 0.0503 54 593 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.872 0.693 – 1.1 0.246 81 953 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.896 0.661 – 1.21 0.479 47 581 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.91 0.706 – 1.17 0.464 72 859 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.952 0.846 – 1.07 0.41 306 3285 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.949 0.805 – 1.12 0.53 153 1554 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.92 0.762 – 1.11 0.38 114 1299 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.988 0.786 – 1.24 0.915 76 870 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.954 0.864 – 1.05 0.349 414 4400 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.807 0.627 – 1.04 0.0951 60 635 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.972 0.865 – 1.09 0.634 297 3254 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.97 0.781 – 1.21 0.784 88 1308 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.825 0.59 – 1.15 0.262 36 648 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.11 0.932 – 1.33 0.238 133 1586 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.02 0.798 – 1.31 0.869 64 704 exclusion phecode
760 Back pain Symptoms 0.972 0.949 – 0.996 0.0222 7241 82599 exclusion phecode
761 Cervicalgia Symptoms 0.92 0.868 – 0.976 0.00537 1226 13386 exclusion phecode
764 Sciatica Symptoms 0.955 0.907 – 1.01 0.0862 1561 17542 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.04 0.96 – 1.12 0.366 749 8615 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 0.973 0.881 – 1.07 0.591 414 4712 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.929 0.853 – 1.01 0.0932 563 6326 exclusion phecode
771.1 Swelling of limb Symptoms 1 0.962 – 1.04 0.977 2688 33176 exclusion phecode
772 Symptoms of the muscles Symptoms 0.963 0.873 – 1.06 0.452 423 4807 exclusion phecode
773 Pain in limb Symptoms 0.998 0.966 – 1.03 0.916 3953 45671 exclusion phecode
780 Hypothermia/Chills Symptoms 1.09 0.89 – 1.33 0.405 97 1231 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.975 0.919 – 1.03 0.39 1200 13658 exclusion phecode
782.3 Edema Symptoms 0.913 0.848 – 0.983 0.0157 745 11377 exclusion phecode
782.6 Pallor and flushing Symptoms 0.88 0.732 – 1.06 0.171 119 1247 exclusion phecode
783 Fever of unknown origin Symptoms 0.985 0.944 – 1.03 0.463 2439 28217 exclusion phecode
785 Abdominal pain Symptoms 0.985 0.973 – 0.997 0.017 28423 225671 exclusion phecode
788 Syncope and collapse Symptoms 0.994 0.967 – 1.02 0.673 5658 63507 exclusion phecode
789 Nausea and vomiting Symptoms 0.969 0.946 – 0.992 0.00915 7405 85578 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 0.981 0.788 – 1.22 0.862 87 1038 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.09 0.775 – 1.52 0.633 38 573 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 0.992 0.958 – 1.03 0.627 3644 41750 exclusion phecode
791 Gangrene Symptoms 0.888 0.78 – 1.01 0.0726 244 3880 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.802 0.638 – 1.01 0.0592 76 727 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.965 0.775 – 1.2 0.75 85 945 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 0.964 0.864 – 1.08 0.518 349 3993 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.27 1.03 – 1.57 0.0264 96 1018 exclusion phecode
797 Shock Symptoms 1.14 0.912 – 1.44 0.245 77 1011 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.29 0.97 – 1.72 0.08 46 639 exclusion phecode
798 Malaise and fatigue Symptoms 1.01 0.968 – 1.06 0.597 2176 24992 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1 0.911 – 1.11 0.926 447 4590 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 0.961 0.933 – 0.99 0.00919 4863 50960 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.972 0.915 – 1.03 0.356 1178 12464 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.15 0.941 – 1.4 0.175 105 1222 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.926 0.879 – 0.976 0.00383 1569 16175 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 1.03 0.943 – 1.13 0.494 532 5519 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.986 0.936 – 1.04 0.601 1561 16475 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 0.975 0.921 – 1.03 0.38 1313 13664 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.03 0.938 – 1.13 0.539 488 5176 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 1.01 0.983 – 1.04 0.481 6088 61074 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1 0.945 – 1.07 0.881 1139 12241 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.02 0.985 – 1.05 0.284 3930 38861 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.989 0.93 – 1.05 0.731 1111 10928 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.983 0.943 – 1.03 0.428 2464 24889 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.02 0.951 – 1.09 0.63 927 9901 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.02 0.929 – 1.11 0.714 526 5437 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.02 0.951 – 1.09 0.607 887 9451 exclusion phecode
817 Concussion Injuries & Poisonings 0.931 0.801 – 1.08 0.351 180 1822 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.959 0.856 – 1.07 0.468 333 3559 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.975 0.933 – 1.02 0.257 2173 22133 exclusion phecode
823 Torus fracture Injuries & Poisonings 0.95 0.895 – 1.01 0.0853 1226 12588 exclusion phecode
830 Dislocation Injuries & Poisonings 1.01 0.962 – 1.07 0.603 1519 15494 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.98 0.961 – 0.999 0.0401 10995 112652 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.986 0.885 – 1.1 0.795 366 3840 exclusion phecode
840 Sprains and strains Injuries & Poisonings 1 0.898 – 1.12 0.946 358 3560 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.993 0.958 – 1.03 0.677 3428 38344 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.01 0.826 – 1.24 0.902 94 1115 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 0.831 0.734 – 0.942 0.00377 276 3525 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.944 0.881 – 1.01 0.104 866 12213 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.03 0.96 – 1.11 0.376 734 8833 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.928 0.886 – 0.972 0.00171 1936 22544 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 0.968 0.925 – 1.01 0.157 2013 23394 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 0.993 0.719 – 1.37 0.966 40 530 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.977 0.937 – 1.02 0.294 2338 25149 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.921 0.792 – 1.07 0.283 183 1967 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 0.959 0.801 – 1.15 0.653 125 1439 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.99 0.945 – 1.04 0.676 1943 20767 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.03 0.872 – 1.22 0.71 148 1535 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 1.6 1.18 – 2.18 0.00258 48 511 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 0.991 0.953 – 1.03 0.629 2888 29962 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.21 0.877 – 1.66 0.25 41 369 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.918 0.708 – 1.19 0.518 62 656 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.835 0.692 – 1.01 0.0582 118 1315 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.01 0.904 – 1.13 0.854 349 3368 exclusion phecode
873 Broken tooth Injuries & Poisonings 0.886 0.754 – 1.04 0.142 158 1673 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 0.827 0.668 – 1.02 0.0793 87 1237 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1 0.834 – 1.21 0.962 113 1185 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.02 0.954 – 1.09 0.545 910 9756 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 0.984 0.946 – 1.02 0.425 2732 30875 exclusion phecode
916 Contusion Injuries & Poisonings 0.91 0.852 – 0.973 0.00536 958 10427 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.953 0.796 – 1.14 0.601 134 1399 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1 0.882 – 1.14 0.949 250 2641 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 1.03 0.877 – 1.21 0.72 168 1712 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.981 0.928 – 1.04 0.509 1350 15276 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.06 0.904 – 1.25 0.456 152 1568 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.04 0.805 – 1.34 0.765 62 732 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.904 0.809 – 1.01 0.0742 333 4070 exclusion phecode
947 Urticaria Injuries & Poisonings 0.973 0.856 – 1.11 0.676 249 2770 exclusion phecode
949 Allergies, other Injuries & Poisonings 0.966 0.855 – 1.09 0.585 280 3065 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.955 0.85 – 1.07 0.446 296 3088 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.941 0.801 – 1.11 0.464 158 1935 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.967 0.861 – 1.09 0.571 310 3587 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.28 0.891 – 1.83 0.183 30 385 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.29 0.979 – 1.7 0.0698 51 506 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.974 0.956 – 0.992 0.00492 12268 135935 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.974 0.955 – 0.993 0.00919 10735 118729 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 0.936 0.823 – 1.06 0.315 253 3125 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1 0.919 – 1.09 0.976 575 6701 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.06 0.916 – 1.22 0.444 192 2752 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.04 0.9 – 1.21 0.587 188 2693 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.02 0.865 – 1.2 0.814 148 1787 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.08 0.897 – 1.3 0.42 121 1978 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.09 0.903 – 1.32 0.366 116 1929 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.968 0.937 – 1 0.0486 3968 45867 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.975 0.906 – 1.05 0.495 758 8661 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.989 0.884 – 1.11 0.842 334 3867 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.95 0.837 – 1.08 0.423 253 2948 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.875 0.784 – 0.978 0.0185 347 4037 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.956 0.863 – 1.06 0.387 404 4411 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 0.936 0.885 – 0.99 0.0207 1325 15609 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.933 0.779 – 1.12 0.456 121 1510 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.899 0.767 – 1.05 0.191 157 2049 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.92 0.696 – 1.22 0.56 51 670 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 0.954 0.751 – 1.21 0.703 66 835 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.836 0.6 – 1.17 0.293 35 711 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.993 0.74 – 1.33 0.962 41 509 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.893 0.648 – 1.23 0.487 39 449 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.835 0.706 – 0.989 0.0369 143 1740 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 0.878 0.799 – 0.965 0.00684 458 5403 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.866 0.731 – 1.03 0.0955 136 1611 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.38 1.03 – 1.85 0.0299 45 460 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 0.975 0.754 – 1.26 0.848 61 764 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 1.17 0.944 – 1.46 0.15 86 877 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.976 0.744 – 1.28 0.862 53 617 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 0.968 0.925 – 1.01 0.162 2013 21824 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 0.986 0.937 – 1.04 0.598 1560 21063 exclusion phecode
994.2 Sepsis Injuries & Poisonings 0.986 0.937 – 1.04 0.598 1560 21063 exclusion phecode
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