Departments of Anesthesiology and Biostatistics | University of Michigan

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ExPRSweb

Compare evaluated PRS models, inspect score-level performance, and follow results into PheWAS analyses.

Scores Estimated glomerular filtration rate based on creatinine UK Biobank (UKB) PheWAS analysis

Estimated glomerular filtration rate based on creatinine — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID exprsweb-egfr-creatine-egfrcrea-overall-ea-prscs-ukb-20211120Legacy PRSCSPRS-CSLarge GWAS

Evaluation cohort: UK Biobank (UKB).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: study-defined normal-range subset.

For this ExPRS, the exclusion sensitivity scan keeps only the study-defined normal-range subset for Estimated glomerular filtration rate based on creatinine before rerunning the PheWAS. The preserved release does not include numeric bounds for this trait. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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Signal overview

The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.

114 rows visible 16 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 0.992 0.971 – 1.01 0.49 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 0.978 0.94 – 1.02 0.26 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.955 0.881 – 1.03 0.255 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 1.02 0.948 – 1.09 0.644 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 0.912 0.696 – 1.19 0.503 55 550 all phecode
010 Tuberculosis Infectious Diseases 1.08 0.924 – 1.26 0.335 166 1659 all phecode
038 Septicemia Infectious Diseases 0.98 0.949 – 1.01 0.211 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 0.959 0.894 – 1.03 0.244 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.03 0.937 – 1.12 0.584 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 1.02 0.999 – 1.04 0.0668 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.03 0.992 – 1.07 0.125 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 1.03 0.979 – 1.08 0.247 1641 16433 all phecode
041.4 E. coli Infectious Diseases 1.01 0.972 – 1.05 0.582 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 1.02 0.919 – 1.13 0.732 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.12 0.909 – 1.38 0.285 95 949 all phecode
054 Herpes simplex Infectious Diseases 1.04 0.903 – 1.2 0.583 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 1.02 0.937 – 1.11 0.64 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 1.01 0.797 – 1.28 0.94 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.04 0.865 – 1.24 0.706 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.07 0.935 – 1.22 0.339 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 0.988 0.873 – 1.12 0.847 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 0.944 0.855 – 1.04 0.247 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.978 0.828 – 1.15 0.792 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.908 0.752 – 1.1 0.316 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 1.06 0.995 – 1.14 0.0706 1004 10036 all phecode
079 Viral infection Infectious Diseases 0.975 0.938 – 1.01 0.213 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 0.809 0.625 – 1.05 0.107 64 640 all phecode
080 Postoperative infection Infectious Diseases 1.02 0.988 – 1.05 0.245 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.01 0.971 – 1.05 0.584 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.07 0.834 – 1.37 0.605 71 709 all phecode
1000 Burns Injuries & Poisonings 1.05 0.964 – 1.14 0.267 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 1.02 0.961 – 1.08 0.513 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 0.991 0.964 – 1.02 0.534 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1 0.888 – 1.13 0.997 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 1.03 0.973 – 1.08 0.336 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 1.02 0.901 – 1.16 0.723 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 1.08 0.946 – 1.22 0.265 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.04 0.975 – 1.11 0.229 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 1.01 0.992 – 1.04 0.211 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 0.999 0.972 – 1.03 0.923 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.02 0.996 – 1.04 0.115 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 1.11 0.919 – 1.35 0.27 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.08 0.962 – 1.21 0.197 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.11 0.871 – 1.42 0.393 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 1.04 1.01 – 1.08 0.0102 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1 0.987 – 1.02 0.729 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.03 0.912 – 1.16 0.643 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 1.03 0.908 – 1.16 0.679 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.98 0.777 – 1.24 0.868 74 756 all phecode
110.12 Althete's foot Infectious Diseases 1.12 0.945 – 1.33 0.189 141 1410 all phecode
112 Candidiasis Infectious Diseases 1.02 0.978 – 1.07 0.338 2126 21275 all phecode
117 Mycoses Infectious Diseases 0.914 0.806 – 1.04 0.158 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 0.884 0.756 – 1.03 0.122 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 1.11 0.896 – 1.39 0.328 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 1.05 0.817 – 1.36 0.693 69 689 all phecode
134 Helminthiases Infectious Diseases 1.14 0.959 – 1.36 0.136 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.16 0.953 – 1.4 0.14 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.05 0.908 – 1.21 0.515 205 2050 all phecode
145 Cancer of mouth Neoplasms 1.01 0.933 – 1.1 0.769 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 0.907 0.807 – 1.02 0.0998 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.08 0.887 – 1.31 0.445 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.09 0.83 – 1.43 0.532 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.03 0.954 – 1.12 0.416 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 1.03 0.902 – 1.17 0.693 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 0.934 0.823 – 1.06 0.286 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 1.17 0.903 – 1.52 0.232 57 570 all phecode
150 Cancer of esophagus Neoplasms 0.992 0.92 – 1.07 0.825 762 7630 all phecode
151 Cancer of stomach Neoplasms 0.969 0.888 – 1.06 0.483 569 5696 all phecode
153 Colorectal cancer Neoplasms 0.999 0.969 – 1.03 0.929 4580 45799 all phecode
153.2 Colon cancer Neoplasms 0.997 0.961 – 1.03 0.867 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.994 0.951 – 1.04 0.787 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.04 0.937 – 1.15 0.482 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.17 0.994 – 1.37 0.0593 158 1580 all phecode
157 Pancreatic cancer Neoplasms 0.999 0.922 – 1.08 0.984 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.959 0.9 – 1.02 0.201 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.01 0.982 – 1.04 0.504 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.937 0.812 – 1.08 0.371 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.958 0.83 – 1.11 0.562 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.07 0.922 – 1.24 0.377 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 0.98 0.76 – 1.26 0.879 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 1.01 0.969 – 1.05 0.715 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 0.995 0.953 – 1.04 0.825 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.962 0.872 – 1.06 0.446 437 4364 all phecode
170.1 Bone cancer Neoplasms 0.87 0.726 – 1.04 0.134 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 0.971 0.867 – 1.09 0.611 331 3303 all phecode
172 Skin cancer Neoplasms 1 0.984 – 1.02 0.827 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.988 0.949 – 1.03 0.536 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 0.988 0.95 – 1.03 0.55 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1.01 0.988 – 1.03 0.465 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 0.987 0.912 – 1.07 0.747 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.946 0.814 – 1.1 0.472 181 1818 all phecode
174 Breast cancer Neoplasms 1.01 0.989 – 1.03 0.45 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 1 0.986 – 1.02 0.621 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1 0.984 – 1.02 0.773 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.13 0.935 – 1.35 0.211 115 1148 all phecode
175 Acquired absence of breast Neoplasms 1.01 0.968 – 1.05 0.671 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 1.01 0.966 – 1.05 0.666 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 1.02 0.899 – 1.15 0.779 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1 0.96 – 1.05 0.868 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 0.994 0.939 – 1.05 0.842 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 1.02 0.968 – 1.08 0.42 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.02 0.954 – 1.09 0.566 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.03 0.963 – 1.1 0.388 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.1 0.975 – 1.23 0.124 305 3049 all phecode
185 Cancer of prostate Neoplasms 1.03 1.01 – 1.06 0.0181 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 0.966 0.878 – 1.06 0.483 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.92 0.723 – 1.17 0.499 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.975 0.863 – 1.1 0.682 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.05 0.868 – 1.27 0.607 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.993 0.961 – 1.02 0.648 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.959 0.9 – 1.02 0.191 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.957 0.897 – 1.02 0.176 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.909 0.709 – 1.17 0.452 66 660 all phecode
189.2 Cancer of bladder Neoplasms 0.992 0.951 – 1.03 0.701 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.978 0.935 – 1.02 0.331 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.896 0.756 – 1.06 0.206 144 1439 all phecode
190 Cancer of eye Neoplasms 0.999 0.857 – 1.16 0.99 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.07 0.988 – 1.16 0.0958 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1.07 0.978 – 1.16 0.147 566 5650 all phecode
191.11 Cancer of brain Neoplasms 1.06 0.968 – 1.16 0.216 525 5240 all phecode
193 Thyroid cancer Neoplasms 1.16 1.04 – 1.3 0.00852 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 0.951 0.774 – 1.17 0.632 95 949 all phecode
195 Cancer, suspected or other Neoplasms 1.01 0.997 – 1.03 0.101 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.01 0.997 – 1.03 0.109 16267 159497 all phecode
197 Chemotherapy Neoplasms 0.999 0.985 – 1.01 0.908 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 0.996 0.975 – 1.02 0.698 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.998 0.97 – 1.03 0.886 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.965 0.924 – 1.01 0.107 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1 0.949 – 1.05 1 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1 0.963 – 1.04 0.911 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.991 0.923 – 1.06 0.8 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 0.988 0.945 – 1.03 0.588 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.963 0.83 – 1.12 0.612 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.05 0.994 – 1.11 0.0787 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 0.9 0.728 – 1.11 0.335 95 950 all phecode
200 Myeloproliferative disease Neoplasms 1.04 0.977 – 1.11 0.207 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 1.09 0.979 – 1.21 0.12 387 3867 all phecode
201 Hodgkin's disease Neoplasms 0.912 0.803 – 1.04 0.159 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.952 0.912 – 0.995 0.0287 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.94 0.895 – 0.987 0.0133 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 0.938 0.841 – 1.05 0.256 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 0.953 0.874 – 1.04 0.278 581 5824 all phecode
204 Leukemia Neoplasms 0.973 0.924 – 1.02 0.286 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 0.93 0.853 – 1.01 0.103 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.827 0.628 – 1.09 0.177 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.926 0.845 – 1.02 0.104 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 0.962 0.874 – 1.06 0.434 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.967 0.863 – 1.08 0.559 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.982 0.825 – 1.17 0.838 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 0.957 0.876 – 1.05 0.332 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 1.01 0.992 – 1.02 0.359 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.04 0.976 – 1.11 0.216 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.01 0.979 – 1.04 0.607 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.905 0.811 – 1.01 0.0731 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.06 0.943 – 1.19 0.339 318 3187 all phecode
214 Lipoma Neoplasms 1.01 0.981 – 1.03 0.582 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.01 0.978 – 1.04 0.585 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.932 0.875 – 0.992 0.027 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 0.993 0.97 – 1.02 0.562 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.951 0.876 – 1.03 0.228 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 0.934 0.858 – 1.02 0.112 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 0.998 0.978 – 1.02 0.855 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 0.995 0.975 – 1.02 0.616 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.05 0.938 – 1.17 0.411 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 0.992 0.94 – 1.05 0.781 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.94 0.817 – 1.08 0.383 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.909 0.771 – 1.07 0.253 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.99 0.85 – 1.15 0.894 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 1.04 0.869 – 1.25 0.662 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.902 0.698 – 1.17 0.432 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.01 0.943 – 1.09 0.731 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.01 0.937 – 1.09 0.814 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.03 0.797 – 1.32 0.835 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.03 0.908 – 1.17 0.647 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.03 0.958 – 1.1 0.452 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.03 0.885 – 1.2 0.713 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.01 0.909 – 1.12 0.857 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.03 0.915 – 1.15 0.654 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.997 0.947 – 1.05 0.915 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.986 0.945 – 1.03 0.506 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.04 0.954 – 1.13 0.401 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1 0.939 – 1.06 0.992 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.99 0.9 – 1.09 0.838 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.982 0.907 – 1.06 0.662 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.04 0.99 – 1.09 0.119 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 0.98 0.889 – 1.08 0.678 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.07 0.865 – 1.31 0.552 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 0.852 0.715 – 1.02 0.0745 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 0.999 0.982 – 1.02 0.874 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.993 0.934 – 1.06 0.819 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.979 0.796 – 1.2 0.842 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.999 0.982 – 1.02 0.902 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 0.927 0.822 – 1.05 0.216 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.926 0.806 – 1.06 0.281 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.93 0.808 – 1.07 0.313 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.05 0.948 – 1.17 0.344 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.01 0.993 – 1.02 0.324 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.978 0.941 – 1.02 0.271 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.906 0.795 – 1.03 0.142 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.998 0.788 – 1.26 0.985 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.952 0.866 – 1.05 0.311 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.02 0.868 – 1.21 0.784 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.01 0.995 – 1.03 0.194 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.04 0.846 – 1.28 0.699 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.963 0.834 – 1.11 0.608 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.983 0.921 – 1.05 0.596 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 0.992 0.905 – 1.09 0.859 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.02 0.945 – 1.11 0.572 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.01 0.89 – 1.15 0.883 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.04 0.939 – 1.15 0.458 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.02 0.851 – 1.22 0.853 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.01 0.904 – 1.12 0.9 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.961 0.908 – 1.02 0.157 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.03 0.963 – 1.1 0.398 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.02 0.953 – 1.09 0.547 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1 0.93 – 1.08 0.998 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.13 0.955 – 1.34 0.155 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.04 0.964 – 1.13 0.306 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.12 0.966 – 1.29 0.137 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.05 0.858 – 1.28 0.654 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.01 0.884 – 1.14 0.928 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.14 0.926 – 1.4 0.215 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.936 0.798 – 1.1 0.412 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.09 1 – 1.18 0.039 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.1 0.944 – 1.27 0.228 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.11 0.914 – 1.35 0.293 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.06 0.841 – 1.33 0.625 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.11 0.995 – 1.23 0.0625 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.11 0.993 – 1.23 0.0657 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.13 0.995 – 1.29 0.0603 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.13 0.986 – 1.31 0.0776 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 1 0.851 – 1.18 0.984 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.05 0.89 – 1.24 0.565 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.948 0.775 – 1.16 0.603 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 0.97 0.82 – 1.15 0.718 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.894 0.772 – 1.03 0.133 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 1.11 0.839 – 1.46 0.478 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 1.02 0.948 – 1.09 0.623 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 0.986 0.929 – 1.05 0.65 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1 0.93 – 1.08 0.943 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.975 0.884 – 1.07 0.606 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.885 0.705 – 1.11 0.29 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.947 0.832 – 1.08 0.415 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 0.871 0.778 – 0.975 0.0161 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.894 0.794 – 1.01 0.0621 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.894 0.786 – 1.02 0.0867 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 0.862 0.743 – 1 0.052 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 0.979 0.807 – 1.19 0.825 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.05 0.818 – 1.34 0.719 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.22 1.04 – 1.44 0.0139 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.24 1.05 – 1.48 0.0134 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.01 0.995 – 1.02 0.261 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.01 0.995 – 1.02 0.281 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.01 0.995 – 1.02 0.259 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.867 0.657 – 1.15 0.315 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.929 0.791 – 1.09 0.37 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.06 0.924 – 1.22 0.405 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.01 0.973 – 1.04 0.7 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 1 0.964 – 1.04 0.989 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.03 0.852 – 1.25 0.759 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.02 0.941 – 1.11 0.58 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.02 0.932 – 1.11 0.694 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.04 0.99 – 1.08 0.123 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 1.18 1.09 – 1.28 4.53e-05 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.08 0.972 – 1.2 0.152 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.953 0.898 – 1.01 0.114 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.962 0.821 – 1.13 0.635 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.01 0.989 – 1.04 0.301 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.01 0.978 – 1.04 0.565 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.07 0.936 – 1.22 0.334 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.02 0.968 – 1.07 0.535 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 0.975 0.912 – 1.04 0.451 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.02 0.97 – 1.08 0.392 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.05 0.993 – 1.12 0.0827 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 1.04 0.981 – 1.11 0.173 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 1.12 0.924 – 1.36 0.248 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 1 0.964 – 1.04 0.94 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 1.02 0.924 – 1.12 0.719 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 0.955 0.802 – 1.14 0.601 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 0.995 0.929 – 1.07 0.882 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.945 0.849 – 1.05 0.297 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.952 0.834 – 1.09 0.461 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.02 0.77 – 1.34 0.915 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.02 0.996 – 1.04 0.125 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 1.02 0.996 – 1.04 0.117 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 0.99 0.794 – 1.23 0.931 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.898 0.696 – 1.16 0.411 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.04 0.915 – 1.18 0.555 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 0.986 0.858 – 1.13 0.849 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.985 0.828 – 1.17 0.868 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 0.978 0.861 – 1.11 0.738 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 1 0.978 – 1.02 0.934 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1 0.977 – 1.03 0.917 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.988 0.896 – 1.09 0.81 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 1.01 0.953 – 1.08 0.659 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 1.02 0.959 – 1.09 0.492 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 1.02 0.943 – 1.1 0.656 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.06 0.91 – 1.25 0.431 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 1.01 0.868 – 1.18 0.87 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 0.905 0.686 – 1.19 0.481 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 0.935 0.795 – 1.1 0.414 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 0.905 0.694 – 1.18 0.462 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.982 0.791 – 1.22 0.872 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 0.862 0.724 – 1.03 0.0939 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.832 0.681 – 1.02 0.0717 103 1059 all phecode
284 Aplastic anemia Hematopoietic 0.962 0.872 – 1.06 0.438 435 4357 all phecode
285 Other anemias Hematopoietic 0.993 0.975 – 1.01 0.491 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.932 0.823 – 1.06 0.273 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 0.952 0.88 – 1.03 0.225 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.974 0.88 – 1.08 0.612 414 4147 all phecode
286 Coagulation defects Hematopoietic 0.942 0.88 – 1.01 0.0816 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 0.92 0.837 – 1.01 0.0859 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 0.922 0.75 – 1.13 0.442 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.916 0.814 – 1.03 0.148 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 0.929 0.724 – 1.19 0.566 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.934 0.75 – 1.16 0.539 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.937 0.844 – 1.04 0.224 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.963 0.916 – 1.01 0.143 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.876 0.73 – 1.05 0.151 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 1.04 0.78 – 1.39 0.792 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 0.954 0.906 – 1.01 0.0787 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 0.948 0.859 – 1.05 0.292 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.12 0.874 – 1.42 0.38 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 0.976 0.944 – 1.01 0.165 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 0.97 0.935 – 1.01 0.105 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 0.97 0.935 – 1.01 0.106 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 0.901 0.71 – 1.14 0.39 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.977 0.911 – 1.05 0.512 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1 0.888 – 1.13 0.969 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 0.99 0.951 – 1.03 0.64 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 0.962 0.877 – 1.05 0.402 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.05 0.933 – 1.19 0.402 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 0.875 0.705 – 1.09 0.224 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.04 0.99 – 1.09 0.124 1929 19281 all phecode
290.1 Dementias Mental Disorders 1.05 0.985 – 1.12 0.131 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 1 0.911 – 1.11 0.921 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 0.908 0.787 – 1.05 0.191 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.02 0.938 – 1.1 0.68 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.03 0.808 – 1.3 0.83 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.04 0.967 – 1.11 0.302 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.02 0.857 – 1.22 0.802 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.05 0.931 – 1.19 0.409 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 1.05 0.955 – 1.16 0.293 436 4376 all phecode
292 Neurological disorders Mental Disorders 1.03 0.997 – 1.06 0.0787 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.02 0.969 – 1.08 0.419 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 1.07 0.92 – 1.24 0.379 190 1907 all phecode
292.3 Memory loss Mental Disorders 1.01 0.938 – 1.1 0.719 696 6978 all phecode
292.4 Altered mental status Mental Disorders 1.06 1.01 – 1.1 0.0165 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 1.08 0.957 – 1.21 0.222 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 1 0.959 – 1.05 0.879 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.983 0.918 – 1.05 0.62 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.03 0.961 – 1.11 0.384 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 1.05 0.963 – 1.14 0.272 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 0.922 0.788 – 1.08 0.31 178 1780 all phecode
295.3 Psychosis Mental Disorders 1.03 0.88 – 1.2 0.723 169 1710 all phecode
296 Mood disorders Mental Disorders 1.02 1 – 1.04 0.0367 12372 123822 all phecode
296.1 Bipolar Mental Disorders 1.02 0.957 – 1.09 0.55 1059 10599 all phecode
296.2 Depression Mental Disorders 1.02 1 – 1.04 0.0352 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 0.989 0.889 – 1.1 0.834 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.02 0.912 – 1.15 0.684 311 3070 all phecode
300 Anxiety disorders Mental Disorders 0.988 0.964 – 1.01 0.329 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 0.988 0.963 – 1.01 0.375 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 0.841 0.709 – 0.997 0.0462 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.973 0.902 – 1.05 0.471 707 7065 all phecode
300.13 Phobia Mental Disorders 0.985 0.899 – 1.08 0.751 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.872 0.732 – 1.04 0.122 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 1 0.757 – 1.33 0.974 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 0.912 0.757 – 1.1 0.331 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.14 0.936 – 1.38 0.195 113 1129 all phecode
301 Personality disorders Mental Disorders 0.924 0.826 – 1.03 0.165 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.884 0.734 – 1.07 0.195 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 1.01 0.893 – 1.14 0.904 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.968 0.88 – 1.06 0.502 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 0.988 0.885 – 1.1 0.822 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 0.863 0.719 – 1.04 0.115 123 1229 all phecode
304 Adjustment reaction Mental Disorders 1.02 0.908 – 1.15 0.724 293 2936 all phecode
305.2 Eating disorder Mental Disorders 1.26 1.02 – 1.55 0.0327 90 900 all phecode
306 Other mental disorder Mental Disorders 1.02 1 – 1.03 0.00784 28056 230087 all phecode
306.9 Tension headache Mental Disorders 1.03 0.916 – 1.15 0.643 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 0.973 0.767 – 1.23 0.818 76 770 all phecode
313.3 Autism Mental Disorders 0.962 0.724 – 1.28 0.791 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 1.1 0.99 – 1.23 0.0744 351 3517 all phecode
315.1 Learning disorder Mental Disorders 0.998 0.846 – 1.18 0.979 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 1.08 0.865 – 1.34 0.508 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 1.01 0.983 – 1.04 0.442 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.965 0.751 – 1.24 0.78 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 0.99 0.972 – 1.01 0.288 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 0.981 0.96 – 1 0.089 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.01 0.937 – 1.08 0.854 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 1.02 1.01 – 1.04 0.00458 19359 185465 all phecode
320 Meningitis Neurological 0.969 0.882 – 1.07 0.523 444 4447 all phecode
323 Encephalitis Neurological 0.976 0.875 – 1.09 0.66 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 1.18 0.941 – 1.49 0.15 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.01 0.9 – 1.14 0.809 292 2916 all phecode
327 Sleep disorders Neurological 0.973 0.917 – 1.03 0.37 1164 11659 all phecode
327.3 Sleep apnea Neurological 0.969 0.94 – 1 0.0472 4428 44318 all phecode
327.4 Insomnia Neurological 1.04 0.892 – 1.21 0.629 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 1.09 0.922 – 1.28 0.322 136 1390 all phecode
331 Other cerebral degenerations Neurological 0.981 0.923 – 1.04 0.532 1142 11416 all phecode
331.1 Hydrocephalus Neurological 0.978 0.893 – 1.07 0.635 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 1.01 0.914 – 1.11 0.868 430 4298 all phecode
332 Parkinson's disease Neurological 0.957 0.9 – 1.02 0.166 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.08 1 – 1.15 0.0362 894 8954 all phecode
333.1 Essential tremor Neurological 1.02 0.892 – 1.18 0.739 216 2157 all phecode
333.2 Myoclonus Neurological 1.04 0.852 – 1.27 0.701 96 958 all phecode
333.4 Torsion dystonia Neurological 1.01 0.891 – 1.15 0.828 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 1 0.954 – 1.05 0.958 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 1.02 0.844 – 1.24 0.829 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 1 0.882 – 1.14 0.977 245 2446 all phecode
335 Multiple sclerosis Neurological 1.01 0.955 – 1.07 0.723 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 1.06 0.931 – 1.2 0.398 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.06 0.837 – 1.33 0.644 72 719 all phecode
338 Pain Neurological 0.983 0.913 – 1.06 0.656 768 7692 all phecode
338.1 Acute pain Neurological 0.979 0.882 – 1.09 0.685 394 3937 all phecode
338.2 Chronic pain Neurological 1 0.9 – 1.11 0.982 380 3817 all phecode
339 Other headache syndromes Neurological 1.02 0.998 – 1.05 0.0772 7819 78241 all phecode
340 Migraine Neurological 1.01 0.976 – 1.05 0.455 2860 28602 all phecode
340.1 Migrain with aura Neurological 0.975 0.847 – 1.12 0.719 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.958 0.839 – 1.09 0.525 252 2535 all phecode
342 Hemiplegia Neurological 1.03 0.976 – 1.09 0.282 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 1.01 0.858 – 1.2 0.862 145 1450 all phecode
344 Other paralytic syndromes Neurological 1.01 0.935 – 1.1 0.759 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1 0.974 – 1.03 0.86 5023 50270 all phecode
345.1 Epilepsy Neurological 0.993 0.926 – 1.07 0.848 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 1.09 0.985 – 1.2 0.0964 439 4385 all phecode
345.12 Partial epilepsy Neurological 1.01 0.894 – 1.15 0.831 277 2776 all phecode
345.3 Convulsions Neurological 0.998 0.955 – 1.04 0.918 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.02 0.862 – 1.21 0.822 144 1438 all phecode
348 Other conditions of brain Neurological 0.998 0.927 – 1.07 0.95 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 0.914 0.806 – 1.04 0.163 268 2678 all phecode
348.4 Cerebral cysts Neurological 1.06 0.893 – 1.26 0.505 133 1350 all phecode
348.7 Coma Neurological 0.995 0.892 – 1.11 0.934 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.01 0.888 – 1.15 0.878 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 1.04 0.938 – 1.15 0.453 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1 0.895 – 1.12 0.997 342 3414 all phecode
350 Abnormal movement Neurological 1.03 0.988 – 1.07 0.17 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 0.95 0.887 – 1.02 0.144 887 8852 all phecode
350.2 Abnormality of gait Neurological 1.06 1 – 1.11 0.038 1596 15969 all phecode
350.3 Lack of coordination Neurological 1.11 0.997 – 1.24 0.0574 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.986 0.747 – 1.3 0.924 54 540 all phecode
351 Other peripheral nerve disorders Neurological 1.01 0.993 – 1.03 0.225 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 1.02 0.962 – 1.08 0.544 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1 0.911 – 1.1 0.979 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.03 0.962 – 1.11 0.38 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 1.02 0.964 – 1.09 0.432 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 1.01 0.834 – 1.22 0.919 114 1138 all phecode
353.2 Nerve root lesions Neurological 1.27 0.964 – 1.66 0.09 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.966 0.823 – 1.13 0.677 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 0.955 0.902 – 1.01 0.109 1361 13648 all phecode
358 Myoneural disorders Neurological 0.896 0.777 – 1.03 0.127 211 2109 all phecode
358.1 Myasthenia gravis Neurological 0.915 0.79 – 1.06 0.236 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.987 0.897 – 1.09 0.796 465 4646 all phecode
359.1 Muscular dystrophies Neurological 0.958 0.795 – 1.15 0.653 122 1219 all phecode
359.2 Myopathy Neurological 1.01 0.904 – 1.12 0.895 360 3597 all phecode
360 Disorders of the globe Sense Organs 0.878 0.783 – 0.984 0.0258 337 3367 all phecode
360.2 Progressive myopia Sense Organs 0.889 0.777 – 1.02 0.0889 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 1 0.969 – 1.04 0.822 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.01 0.954 – 1.07 0.757 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 1.09 0.858 – 1.4 0.469 68 680 all phecode
362 Other retinal disorders Sense Organs 1.04 1.01 – 1.08 0.012 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.06 1.01 – 1.11 0.0106 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.06 1.01 – 1.11 0.00953 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.884 0.755 – 1.04 0.127 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 0.812 0.664 – 0.993 0.0421 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.07 0.995 – 1.15 0.0688 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 1.03 0.885 – 1.2 0.704 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.08 0.858 – 1.36 0.506 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.18 0.985 – 1.42 0.072 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.01 0.864 – 1.18 0.902 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 1.07 0.84 – 1.37 0.577 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.982 0.906 – 1.06 0.655 647 6485 all phecode
364.1 Corneal opacity Sense Organs 0.988 0.803 – 1.22 0.912 90 910 all phecode
364.2 Corneal edema Sense Organs 0.772 0.61 – 0.976 0.0303 79 800 all phecode
364.4 Corneal degenerations Sense Organs 0.952 0.823 – 1.1 0.504 201 2017 all phecode
364.41 Keratoconus Sense Organs 0.937 0.752 – 1.17 0.565 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 0.919 0.798 – 1.06 0.239 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 1.01 0.821 – 1.23 0.953 100 1000 all phecode
365 Glaucoma Sense Organs 1.02 0.989 – 1.05 0.213 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 1.06 0.991 – 1.13 0.0952 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.06 0.994 – 1.13 0.0749 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.01 0.936 – 1.09 0.768 698 6996 all phecode
366 Cataract Sense Organs 1.02 1 – 1.03 0.011 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 1.26 0.988 – 1.6 0.063 69 700 all phecode
366.2 Senile cataract Sense Organs 1.03 1 – 1.05 0.0313 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 0.839 0.68 – 1.04 0.103 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.03 0.987 – 1.07 0.185 2408 24092 all phecode
367.1 Myopia Sense Organs 1.06 1 – 1.13 0.0367 1251 12519 all phecode
367.2 Astigmatism Sense Organs 0.942 0.812 – 1.09 0.427 190 1899 all phecode
367.8 Hypermetropia Sense Organs 0.976 0.858 – 1.11 0.706 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 0.998 0.925 – 1.08 0.966 719 7198 all phecode
368 Visual disturbances Sense Organs 1.06 1.02 – 1.1 0.00134 2962 29648 all phecode
368.1 Amblyopia Sense Organs 1.04 0.956 – 1.14 0.334 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.08 1 – 1.17 0.0372 727 7288 all phecode
368.3 Anisometropia Sense Organs 0.872 0.735 – 1.03 0.116 154 1548 all phecode
368.4 Visual field defects Sense Organs 0.98 0.876 – 1.1 0.728 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 1.07 0.984 – 1.16 0.112 612 6115 all phecode
369 Infection of the eye Sense Organs 1 0.916 – 1.09 0.996 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 1.13 0.942 – 1.35 0.191 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.984 0.855 – 1.13 0.817 213 2128 all phecode
370 Keratitis Sense Organs 1.02 0.904 – 1.16 0.729 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 1.19 1 – 1.42 0.0441 141 1408 all phecode
371 Inflammation of the eye Sense Organs 0.987 0.951 – 1.02 0.5 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.01 0.919 – 1.11 0.852 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 0.983 0.942 – 1.03 0.416 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 0.997 0.925 – 1.07 0.927 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 0.996 0.969 – 1.02 0.79 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 1.01 0.949 – 1.08 0.744 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 1.03 0.978 – 1.08 0.297 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 1.01 0.962 – 1.05 0.804 2204 22031 all phecode
375.2 Epiphora Sense Organs 1.01 0.945 – 1.08 0.739 898 8969 all phecode
376 Disorders of the orbit Sense Organs 0.907 0.728 – 1.13 0.382 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.03 0.928 – 1.15 0.566 361 3618 all phecode
377.1 Optic atrophy Sense Organs 1.13 0.863 – 1.47 0.38 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.989 0.828 – 1.18 0.901 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.04 0.986 – 1.1 0.142 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.04 0.973 – 1.12 0.242 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1 0.872 – 1.16 0.96 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 1.09 0.962 – 1.23 0.182 275 2755 all phecode
379 Other disorders of eye Sense Organs 0.987 0.954 – 1.02 0.454 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 0.957 0.906 – 1.01 0.123 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.01 0.961 – 1.06 0.729 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.15 0.917 – 1.45 0.222 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.01 0.91 – 1.12 0.861 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.13 0.964 – 1.32 0.131 169 1690 all phecode
380 Disorders of external ear Sense Organs 0.933 0.86 – 1.01 0.098 642 6413 all phecode
380.1 Otitis externa Sense Organs 0.995 0.908 – 1.09 0.922 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 0.942 0.843 – 1.05 0.284 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.975 0.933 – 1.02 0.271 2150 21493 all phecode
381.1 Otitis media Sense Organs 0.978 0.931 – 1.03 0.362 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.994 0.927 – 1.07 0.871 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 0.883 0.762 – 1.02 0.0973 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 0.985 0.841 – 1.15 0.855 171 1709 all phecode
381.9 Otorrhea Sense Organs 0.974 0.862 – 1.1 0.68 281 2807 all phecode
382 Otalgia Sense Organs 1.02 0.909 – 1.15 0.728 308 3084 all phecode
383 Otosclerosis Sense Organs 1.05 0.931 – 1.18 0.448 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 0.983 0.929 – 1.04 0.559 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 0.992 0.931 – 1.06 0.802 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.965 0.896 – 1.04 0.349 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 0.951 0.874 – 1.03 0.237 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.964 0.842 – 1.1 0.593 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.981 0.934 – 1.03 0.461 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 0.972 0.893 – 1.06 0.52 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 0.987 0.887 – 1.1 0.816 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 1 0.929 – 1.08 0.984 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.02 0.988 – 1.05 0.24 4582 45806 all phecode
388 Other disorders of ear Sense Organs 1.1 0.955 – 1.27 0.185 202 2017 all phecode
389 Hearing loss Sense Organs 1.01 0.98 – 1.04 0.487 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 1.08 0.982 – 1.19 0.112 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 1 0.909 – 1.1 0.975 450 4497 all phecode
389.4 Tinnitus Sense Organs 1.02 0.931 – 1.12 0.676 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.04 1.01 – 1.07 0.0174 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 1.02 0.985 – 1.06 0.249 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 1.09 1.03 – 1.15 0.00412 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.07 1.01 – 1.14 0.0307 1058 10566 all phecode
395 Heart valve disorders Circulatory System 1.03 0.998 – 1.06 0.0663 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.02 0.985 – 1.06 0.234 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.09 0.965 – 1.23 0.162 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.02 0.836 – 1.25 0.835 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.831 0.679 – 1.02 0.0711 97 970 all phecode
395.6 Heart valve replaced Circulatory System 1.07 1.01 – 1.13 0.0163 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 1.06 0.996 – 1.13 0.0687 1048 10468 all phecode
401 Hypertension Circulatory System 1.01 0.998 – 1.02 0.125 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 1.01 0.998 – 1.02 0.135 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 0.968 0.924 – 1.02 0.18 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 0.978 0.877 – 1.09 0.686 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.966 0.917 – 1.02 0.199 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 0.949 0.8 – 1.13 0.547 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.01 0.953 – 1.06 0.848 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 1 0.992 – 1.02 0.47 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.02 0.987 – 1.04 0.296 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 1.01 0.991 – 1.03 0.289 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 1.01 0.998 – 1.03 0.0828 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.01 0.993 – 1.02 0.273 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.03 0.951 – 1.11 0.481 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.01 0.996 – 1.03 0.125 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.965 0.91 – 1.02 0.242 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 1.05 1 – 1.1 0.0488 1823 18228 all phecode
414.2 ASCVD Circulatory System 1.05 0.826 – 1.34 0.676 72 719 all phecode
415 Pulmonary heart disease Circulatory System 0.992 0.962 – 1.02 0.597 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.874 0.695 – 1.1 0.251 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.03 0.947 – 1.12 0.489 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 0.989 0.898 – 1.09 0.816 448 4475 all phecode
416 Cardiomegaly Circulatory System 1.02 0.981 – 1.06 0.305 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 1.01 0.993 – 1.02 0.409 28599 270106 all phecode
418.1 Precordial pain Circulatory System 0.996 0.962 – 1.03 0.807 3551 35541 all phecode
420 Carditis Circulatory System 1.02 0.979 – 1.07 0.293 2106 21053 all phecode
420.1 Myocarditis Circulatory System 1.05 0.883 – 1.26 0.563 127 1267 all phecode
420.2 Pericarditis Circulatory System 1.04 0.982 – 1.1 0.188 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 0.997 0.867 – 1.15 0.971 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 1.16 0.955 – 1.4 0.138 113 1129 all phecode
420.3 Endocarditis Circulatory System 0.992 0.918 – 1.07 0.84 719 7194 all phecode
425 Cardiomyopathy Circulatory System 1.07 1.01 – 1.13 0.0204 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.06 1 – 1.12 0.0515 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.05 0.883 – 1.26 0.561 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.01 0.86 – 1.19 0.895 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 1.36 1.04 – 1.78 0.0234 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 1.01 0.986 – 1.04 0.39 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1 0.958 – 1.05 0.943 2114 21162 all phecode
426.21 First degree AV block Circulatory System 1.01 0.946 – 1.08 0.766 986 9867 all phecode
426.23 Second degree AV block Circulatory System 1.02 0.926 – 1.12 0.686 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 0.964 0.885 – 1.05 0.402 587 5868 all phecode
426.25 Other heart block Circulatory System 0.96 0.805 – 1.14 0.65 131 1318 all phecode
426.3 Bundle branch block Circulatory System 1.02 0.987 – 1.06 0.208 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 1.02 0.964 – 1.07 0.551 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 1.04 0.986 – 1.09 0.166 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.99 0.866 – 1.13 0.885 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 0.973 0.741 – 1.28 0.843 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.02 0.981 – 1.07 0.284 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.02 0.979 – 1.07 0.326 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 1.02 1.01 – 1.03 0.00483 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.01 0.971 – 1.04 0.695 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1 0.963 – 1.05 0.837 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.03 0.96 – 1.1 0.441 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.02 1 – 1.04 0.0227 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.993 0.958 – 1.03 0.708 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.04 0.98 – 1.1 0.192 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.13 1.01 – 1.26 0.0368 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 1.02 0.956 – 1.09 0.547 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.03 0.966 – 1.1 0.348 952 9541 all phecode
427.6 Premature beats Circulatory System 0.993 0.909 – 1.09 0.878 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 1.02 0.84 – 1.23 0.876 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 1 0.96 – 1.05 0.89 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.996 0.898 – 1.1 0.942 402 4029 all phecode
427.9 Palpitations Circulatory System 1.04 1.01 – 1.08 0.0139 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.04 1.02 – 1.07 0.0022 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.04 0.99 – 1.08 0.131 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 1.04 1.01 – 1.07 0.0113 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.02 0.948 – 1.11 0.552 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 1.2 0.931 – 1.54 0.161 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.03 0.942 – 1.13 0.502 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.05 0.909 – 1.22 0.492 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 1.04 0.996 – 1.09 0.075 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.05 0.974 – 1.12 0.222 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1.01 0.939 – 1.09 0.761 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 1.06 0.933 – 1.2 0.388 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 1.01 0.983 – 1.03 0.635 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.06 0.995 – 1.12 0.0726 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.14 0.99 – 1.31 0.0684 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.01 0.98 – 1.04 0.489 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.01 0.957 – 1.06 0.81 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 0.986 0.948 – 1.02 0.459 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 0.978 0.936 – 1.02 0.337 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 1.04 0.939 – 1.15 0.455 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1 0.948 – 1.06 0.892 1279 12783 all phecode
440 Atherosclerosis Circulatory System 1.02 0.963 – 1.08 0.526 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.12 0.929 – 1.36 0.229 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.06 0.989 – 1.15 0.0947 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 0.93 0.822 – 1.05 0.245 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 0.982 0.903 – 1.07 0.665 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.974 0.863 – 1.1 0.667 283 2827 all phecode
442 Other aneurysm Circulatory System 1.03 0.987 – 1.08 0.157 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 1.03 0.977 – 1.09 0.266 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.01 0.944 – 1.08 0.789 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.02 0.836 – 1.25 0.837 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.14 0.976 – 1.34 0.0971 169 1696 all phecode
442.4 Arterial dissection Circulatory System 1.09 0.834 – 1.42 0.539 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 0.945 0.818 – 1.09 0.439 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 0.997 0.965 – 1.03 0.868 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 1.01 0.953 – 1.08 0.681 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.03 0.923 – 1.14 0.643 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 0.997 0.964 – 1.03 0.856 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.993 0.953 – 1.03 0.732 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 0.981 0.916 – 1.05 0.587 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.04 0.948 – 1.13 0.433 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.01 0.943 – 1.09 0.727 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 0.988 0.85 – 1.15 0.875 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 1.05 0.943 – 1.16 0.396 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 1.04 0.91 – 1.19 0.555 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 0.98 0.926 – 1.04 0.473 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 0.982 0.916 – 1.05 0.618 868 8712 all phecode
448 Disease of capillaries Circulatory System 0.905 0.763 – 1.07 0.254 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.991 0.918 – 1.07 0.817 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.992 0.961 – 1.03 0.651 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.989 0.956 – 1.02 0.524 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 1.02 0.938 – 1.12 0.612 564 5645 all phecode
454 Varicose veins Circulatory System 1.02 1 – 1.04 0.0217 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1.02 1 – 1.04 0.0277 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.03 0.946 – 1.11 0.542 624 6325 all phecode
455 Hemorrhoids Circulatory System 1.01 0.992 – 1.02 0.442 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.96 0.826 – 1.11 0.589 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.14 0.92 – 1.4 0.238 97 967 all phecode
458 Hypotension Circulatory System 1 0.976 – 1.03 0.831 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 0.992 0.937 – 1.05 0.768 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.07 0.934 – 1.22 0.336 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 0.997 0.963 – 1.03 0.882 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 1.01 0.994 – 1.03 0.239 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 1.15 0.969 – 1.37 0.11 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 1.01 0.996 – 1.03 0.156 16103 159422 all phecode
464 Acute sinusitis Respiratory 1.04 0.893 – 1.21 0.621 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.02 0.973 – 1.06 0.47 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 0.987 0.919 – 1.06 0.71 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.965 0.819 – 1.14 0.675 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.996 0.966 – 1.03 0.791 4654 46553 all phecode
471 Nasal polyps Respiratory 1.02 0.985 – 1.06 0.247 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.985 0.922 – 1.05 0.665 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 0.977 0.938 – 1.02 0.257 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 1.07 0.875 – 1.31 0.512 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.898 0.791 – 1.02 0.0943 264 2647 all phecode
473.4 Voice disturbance Respiratory 0.951 0.894 – 1.01 0.12 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 0.951 0.906 – 0.999 0.0436 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 0.932 0.855 – 1.02 0.115 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.97 0.912 – 1.03 0.322 1122 11199 all phecode
475 Chronic sinusitis Respiratory 0.996 0.957 – 1.04 0.862 2589 25882 all phecode
476 Allergic rhinitis Respiratory 0.982 0.921 – 1.05 0.573 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.01 0.966 – 1.05 0.743 2447 24452 all phecode
478 Throat pain Respiratory 1.01 0.908 – 1.12 0.864 377 3789 all phecode
479 Other upper respiratory disease Respiratory 1 0.969 – 1.03 0.944 4074 40737 all phecode
480 Pneumonia Respiratory 1.01 0.988 – 1.03 0.422 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 1.02 0.991 – 1.04 0.209 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.01 0.985 – 1.04 0.375 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.34 1.08 – 1.66 0.00828 93 929 all phecode
480.2 Viral pneumonia Respiratory 1.15 0.906 – 1.45 0.252 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.971 0.789 – 1.2 0.783 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.957 0.89 – 1.03 0.243 794 7951 all phecode
481 Influenza Respiratory 1.15 1.02 – 1.28 0.0174 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.921 0.794 – 1.07 0.275 193 1930 all phecode
495 Asthma Respiratory 1 0.992 – 1.02 0.448 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 1.07 0.94 – 1.22 0.301 250 2510 all phecode
496 Chronic airway obstruction Respiratory 0.995 0.975 – 1.02 0.64 10424 101546 all phecode
496.1 Emphysema Respiratory 0.976 0.929 – 1.02 0.322 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 1.01 0.968 – 1.04 0.78 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.02 0.978 – 1.06 0.381 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 1.03 0.98 – 1.08 0.259 1885 18859 all phecode
497 Bronchitis Respiratory 0.978 0.901 – 1.06 0.604 626 6267 all phecode
500 Lung disease due to external agents Respiratory 0.996 0.901 – 1.1 0.933 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1 0.802 – 1.25 0.983 79 784 all phecode
500.2 Pneumoconiosis Respiratory 0.99 0.87 – 1.13 0.885 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.05 0.967 – 1.14 0.253 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.994 0.929 – 1.06 0.863 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.05 0.961 – 1.15 0.271 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.924 0.825 – 1.03 0.167 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 0.779 0.607 – 0.999 0.0495 61 610 all phecode
506 Empyema and pneumothorax Respiratory 1.01 0.954 – 1.08 0.667 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 0.999 0.974 – 1.03 0.969 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.992 0.948 – 1.04 0.744 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.01 0.966 – 1.05 0.786 2599 26031 all phecode
509.1 Respiratory failure Respiratory 1.01 0.962 – 1.05 0.777 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 1.02 0.975 – 1.07 0.36 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 0.996 0.838 – 1.18 0.959 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.968 0.872 – 1.08 0.546 386 3863 all phecode
510 Other diseases of lung Respiratory 0.996 0.924 – 1.07 0.912 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 1.01 0.984 – 1.03 0.65 9031 90349 all phecode
512.1 Wheezing Respiratory 0.983 0.856 – 1.13 0.81 220 2196 all phecode
512.2 Painful respiration Respiratory 1.02 0.888 – 1.18 0.759 207 2075 all phecode
512.7 Shortness of breath Respiratory 0.997 0.971 – 1.02 0.838 5842 58498 all phecode
512.8 Cough Respiratory 1.02 0.981 – 1.06 0.327 2866 28642 all phecode
512.9 Other dyspnea Respiratory 1.02 0.948 – 1.09 0.667 914 9124 all phecode
513 Respiratory abnormalities Respiratory 0.998 0.918 – 1.08 0.964 611 6112 all phecode
513.3 Hypoventilation Respiratory 1.06 0.846 – 1.33 0.614 83 830 all phecode
513.4 Hyperventilation Respiratory 1.01 0.888 – 1.14 0.93 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 1.02 0.866 – 1.21 0.774 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 1.01 0.969 – 1.05 0.634 2465 24673 all phecode
516 Abnormal sputum Respiratory 1.01 0.971 – 1.06 0.517 2132 21335 all phecode
516.1 Hemoptysis Respiratory 1.02 0.975 – 1.07 0.39 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1 0.984 – 1.03 0.661 9366 93681 all phecode
519.2 Respiratory complications Respiratory 1.04 0.931 – 1.17 0.473 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1 0.982 – 1.03 0.745 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.06 0.939 – 1.19 0.368 303 3049 all phecode
520 Disorders of tooth development Digestive 0.978 0.934 – 1.02 0.337 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.948 0.716 – 1.25 0.707 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 0.982 0.942 – 1.02 0.413 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 0.982 0.946 – 1.02 0.344 3016 30245 all phecode
521.1 Dental caries Digestive 0.98 0.944 – 1.02 0.293 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.05 0.999 – 1.1 0.0561 1774 17750 all phecode
522.5 Periapical abscess Digestive 1.07 1.01 – 1.14 0.0249 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 0.978 0.93 – 1.03 0.377 1681 16812 all phecode
523.1 Gingivitis Digestive 0.946 0.775 – 1.15 0.582 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 0.991 0.933 – 1.05 0.776 1165 11650 all phecode
523.31 Acute periodontitis Digestive 1.01 0.932 – 1.09 0.842 666 6667 all phecode
523.32 Chronic periodontitis Digestive 0.948 0.867 – 1.04 0.234 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.979 0.873 – 1.1 0.711 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.992 0.881 – 1.12 0.896 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1 0.965 – 1.04 0.846 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.08 0.854 – 1.37 0.513 72 720 all phecode
526 Diseases of the jaws Digestive 1.01 0.941 – 1.08 0.836 928 9279 all phecode
526.1 Cysts of the jaws Digestive 1.07 0.955 – 1.2 0.247 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.895 0.691 – 1.16 0.402 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.01 0.888 – 1.15 0.857 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1 0.879 – 1.15 0.959 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.903 0.744 – 1.1 0.305 110 1098 all phecode
526.9 Jaw disease NOS Digestive 1.02 0.89 – 1.17 0.758 233 2329 all phecode
527 Diseases of the salivary glands Digestive 1.02 0.942 – 1.1 0.648 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.13 0.903 – 1.41 0.289 84 838 all phecode
527.2 Sialoadenitis Digestive 1.02 0.921 – 1.14 0.663 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 0.989 0.762 – 1.28 0.933 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.14 0.951 – 1.36 0.159 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.994 0.961 – 1.03 0.707 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 1.07 0.973 – 1.18 0.161 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.04 0.938 – 1.15 0.457 389 3884 all phecode
528.12 Oral aphthae Digestive 1.28 1.02 – 1.61 0.0311 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.976 0.839 – 1.14 0.758 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 0.847 0.706 – 1.02 0.0747 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 0.943 0.769 – 1.16 0.575 94 940 all phecode
528.5 Diseases of lips Digestive 1.03 0.952 – 1.11 0.458 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.1 0.979 – 1.24 0.11 308 3079 all phecode
528.7 Sialolithiasis Digestive 1.06 0.94 – 1.19 0.358 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 0.984 0.928 – 1.04 0.595 1232 12312 all phecode
529.1 Glossitis Digestive 1.02 0.908 – 1.15 0.725 299 2986 all phecode
530 Diseases of esophagus Digestive 0.997 0.986 – 1.01 0.639 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.997 0.985 – 1.01 0.631 31253 272429 all phecode
530.11 GERD Digestive 0.995 0.982 – 1.01 0.515 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 1.01 0.986 – 1.04 0.313 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 0.993 0.974 – 1.01 0.52 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1 0.955 – 1.06 0.873 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 0.97 0.925 – 1.02 0.209 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 0.953 0.878 – 1.03 0.254 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.03 0.873 – 1.21 0.73 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.03 0.917 – 1.15 0.648 341 3416 all phecode
530.9 Heartburn Digestive 0.987 0.943 – 1.03 0.574 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.01 0.99 – 1.04 0.25 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.01 0.929 – 1.09 0.846 637 6374 all phecode
531.2 Gastric ulcer Digestive 1.01 0.975 – 1.04 0.694 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 1.02 0.986 – 1.06 0.227 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.04 0.937 – 1.14 0.495 427 4268 all phecode
532 Dysphagia Digestive 1.01 0.983 – 1.03 0.519 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 0.996 0.984 – 1.01 0.506 28078 261548 all phecode
535.1 Acute gastritis Digestive 0.975 0.918 – 1.03 0.395 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 1 0.899 – 1.11 0.994 370 3687 all phecode
535.6 Duodenitis Digestive 0.997 0.974 – 1.02 0.794 7592 75928 all phecode
535.8 Other specified gastritis Digestive 1 0.979 – 1.03 0.87 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.954 0.793 – 1.15 0.618 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.03 0.91 – 1.18 0.603 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 0.974 0.94 – 1.01 0.144 3391 33907 all phecode
540 Appendiceal conditions Digestive 1.01 0.977 – 1.05 0.476 3088 30890 all phecode
540.1 Appendicitis Digestive 1.02 0.979 – 1.06 0.38 2895 28963 all phecode
540.11 Acute appendicitis Digestive 1.02 0.977 – 1.06 0.405 2601 26019 all phecode
550 Abdominal hernia Digestive 1.01 0.998 – 1.02 0.136 45429 282640 all phecode
550.1 Inguinal hernia Digestive 1.02 1.01 – 1.04 0.00401 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 0.998 0.985 – 1.01 0.757 26494 238953 all phecode
550.3 Femoral hernia Digestive 1.03 0.946 – 1.11 0.54 651 6504 all phecode
550.4 Umbilical hernia Digestive 1.01 0.979 – 1.05 0.458 3705 37072 all phecode
550.5 Ventral hernia Digestive 1 0.965 – 1.04 0.981 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.03 0.998 – 1.06 0.0693 4444 44442 all phecode
555.1 Regional enteritis Digestive 1.03 0.98 – 1.08 0.249 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 1.02 0.979 – 1.05 0.396 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.02 0.932 – 1.12 0.673 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 1.08 1.01 – 1.15 0.0158 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 1.1 1.01 – 1.19 0.0232 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.05 0.932 – 1.18 0.417 299 2987 all phecode
557.1 Celiac disease Digestive 0.993 0.946 – 1.04 0.784 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 1.01 0.99 – 1.02 0.43 15492 155105 all phecode
559 Ileostomy status Digestive 1 0.954 – 1.06 0.875 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 0.989 0.957 – 1.02 0.514 3936 39337 all phecode
560.1 Paralytic ileus Digestive 0.964 0.881 – 1.06 0.427 523 5231 all phecode
560.2 Impaction of intestine Digestive 0.98 0.864 – 1.11 0.748 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.02 0.95 – 1.1 0.585 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 0.995 0.96 – 1.03 0.764 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 1.01 0.996 – 1.03 0.125 15772 157686 all phecode
561.1 Diarrhea Digestive 1.02 0.928 – 1.12 0.689 466 4653 all phecode
561.2 Flatulence Digestive 1.03 0.98 – 1.08 0.24 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 1.01 0.996 – 1.02 0.179 26714 211692 all phecode
562.1 Diverticulosis Digestive 1.01 0.996 – 1.02 0.173 26672 211642 all phecode
563 Constipation Digestive 1.01 0.987 – 1.03 0.504 10314 103140 all phecode
564 Functional digestive disorders Digestive 1.01 0.996 – 1.02 0.145 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.01 0.979 – 1.04 0.624 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 0.999 0.949 – 1.05 0.958 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 1.01 0.998 – 1.03 0.0865 15186 151648 all phecode
565 Anal and rectal conditions Digestive 1.01 0.989 – 1.02 0.506 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 1.01 0.984 – 1.03 0.536 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.01 0.945 – 1.08 0.753 929 9293 all phecode
568 Other disorders of peritoneum Digestive 1 0.968 – 1.04 0.833 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1 0.966 – 1.04 0.883 3101 30987 all phecode
569 Other disorders of intestine Digestive 1 0.973 – 1.04 0.782 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.02 0.862 – 1.2 0.829 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 1.1 1 – 1.21 0.043 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 0.984 0.947 – 1.02 0.391 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 0.994 0.945 – 1.04 0.808 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.895 0.741 – 1.08 0.246 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 0.843 0.741 – 0.959 0.00959 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.963 0.902 – 1.03 0.257 976 9804 all phecode
571.81 Portal hypertension Digestive 0.947 0.867 – 1.03 0.227 528 5285 all phecode
572 Ascites (non malignant) Digestive 0.998 0.947 – 1.05 0.926 1544 15454 all phecode
573 Other disorders of liver Digestive 1.04 0.982 – 1.09 0.197 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 0.993 0.803 – 1.23 0.949 96 960 all phecode
573.3 Hepatomegaly Digestive 1 0.891 – 1.13 0.955 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 0.953 0.889 – 1.02 0.179 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 0.963 0.929 – 0.997 0.0333 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 0.92 0.797 – 1.06 0.252 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 0.994 0.978 – 1.01 0.474 15607 156123 all phecode
574.1 Cholelithiasis Digestive 0.992 0.975 – 1.01 0.382 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.983 0.932 – 1.04 0.54 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.984 0.957 – 1.01 0.257 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 1.01 0.968 – 1.05 0.716 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.01 0.975 – 1.05 0.506 2748 27523 all phecode
575 Other biliary tract disease Digestive 1 0.97 – 1.04 0.884 3867 38724 all phecode
575.1 Cholangitis Digestive 0.984 0.897 – 1.08 0.735 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 0.992 0.921 – 1.07 0.829 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.999 0.908 – 1.1 0.986 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 1.02 0.97 – 1.08 0.39 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 0.999 0.937 – 1.06 0.965 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.06 0.953 – 1.19 0.266 348 3488 all phecode
577 Diseases of pancreas Digestive 0.979 0.941 – 1.02 0.296 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 0.954 0.911 – 0.999 0.0452 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 0.958 0.875 – 1.05 0.346 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.944 0.846 – 1.05 0.298 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.995 – 1.02 0.209 20626 206278 all phecode
578.1 Hematemesis Digestive 0.968 0.924 – 1.01 0.171 1958 19564 all phecode
578.2 Blood in stool Digestive 0.985 0.947 – 1.03 0.478 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.02 1 – 1.04 0.0506 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.02 0.994 – 1.05 0.128 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.947 0.899 – 0.998 0.0408 1548 15498 all phecode
579.2 Splenomegaly Digestive 0.946 0.856 – 1.05 0.276 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.08 1.03 – 1.14 0.00263 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.914 0.867 – 0.964 0.000896 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 0.896 0.841 – 0.956 0.000822 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.903 0.705 – 1.16 0.42 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.944 0.792 – 1.13 0.523 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.894 0.833 – 0.959 0.0018 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.959 0.872 – 1.05 0.383 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.976 0.855 – 1.11 0.716 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.966 0.848 – 1.1 0.597 253 2529 all phecode
585 Renal failure Genitourinary 0.957 0.934 – 0.981 0.000578 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 0.983 0.953 – 1.01 0.273 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 0.922 0.874 – 0.973 0.00297 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.918 0.882 – 0.956 3.32e-05 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 1.08 0.981 – 1.18 0.121 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.02 0.986 – 1.06 0.24 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.971 0.841 – 1.12 0.688 208 2089 all phecode
586.11 Small kidney Genitourinary 0.959 0.821 – 1.12 0.599 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.01 0.958 – 1.07 0.628 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.06 0.843 – 1.33 0.622 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.08 1.01 – 1.15 0.0288 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 1.02 0.912 – 1.13 0.773 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.09 0.89 – 1.33 0.413 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 0.906 0.753 – 1.09 0.298 116 1158 all phecode
590 Pyelonephritis Genitourinary 0.992 0.937 – 1.05 0.78 1328 13285 all phecode
591 Urinary tract infection Genitourinary 1.02 1.01 – 1.04 0.0122 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 0.96 0.925 – 0.997 0.0357 2966 29661 all phecode
592.1 Cystitis Genitourinary 0.968 0.932 – 1.01 0.0962 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 0.818 0.688 – 0.971 0.022 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 0.96 0.895 – 1.03 0.251 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.874 0.767 – 0.997 0.0446 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.799 0.677 – 0.942 0.00742 165 1662 all phecode
593 Hematuria Genitourinary 1.01 0.993 – 1.03 0.274 16068 160204 all phecode
594 Urinary calculus Genitourinary 1.08 1.05 – 1.11 2.87e-09 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 1.13 1.09 – 1.17 7.88e-11 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.01 0.939 – 1.09 0.753 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 1.09 1.04 – 1.14 6.31e-05 2401 24024 all phecode
594.8 Renal colic Genitourinary 1.05 1.01 – 1.1 0.0273 2050 20500 all phecode
595 Hydronephrosis Genitourinary 0.995 0.95 – 1.04 0.829 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 0.997 0.976 – 1.02 0.752 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 1.03 0.982 – 1.08 0.236 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 0.986 0.937 – 1.04 0.581 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.01 0.982 – 1.05 0.384 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.02 0.987 – 1.06 0.21 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 0.851 0.675 – 1.07 0.173 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.02 0.985 – 1.06 0.261 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.18 1.04 – 1.33 0.0085 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.994 – 1.02 0.254 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 0.984 0.836 – 1.16 0.845 166 1670 all phecode
599.2 Retention of urine Genitourinary 1.03 1.01 – 1.06 0.0129 6718 67168 all phecode
599.3 Dysuria Genitourinary 0.978 0.921 – 1.04 0.455 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 0.999 0.977 – 1.02 0.935 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.03 0.994 – 1.06 0.11 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 1.16 0.938 – 1.42 0.174 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.08 0.832 – 1.41 0.559 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 1.01 0.966 – 1.06 0.594 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 1.01 0.994 – 1.03 0.177 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 1.02 0.972 – 1.06 0.479 2081 20818 all phecode
601.1 Prostatitis Genitourinary 1.03 0.979 – 1.09 0.241 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 1.1 0.96 – 1.26 0.174 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 1.04 0.968 – 1.11 0.306 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.03 0.794 – 1.33 0.844 59 588 all phecode
601.4 Balanoposthitis Genitourinary 1.04 0.924 – 1.18 0.49 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.964 0.858 – 1.08 0.534 303 3019 all phecode
602 Other disorders of prostate Genitourinary 1.06 0.999 – 1.12 0.0546 1341 13408 all phecode
603 Other disorders of testis Genitourinary 1.01 0.968 – 1.06 0.604 2150 21512 all phecode
603.1 Hydrocele Genitourinary 0.987 0.933 – 1.05 0.659 1339 13402 all phecode
604 Disorders of penis Genitourinary 1.01 0.971 – 1.04 0.709 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.994 0.956 – 1.03 0.769 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.06 0.941 – 1.2 0.334 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 1.03 0.987 – 1.07 0.186 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.13 0.982 – 1.3 0.089 214 2138 all phecode
609.1 Infertility, male Genitourinary 1.27 0.975 – 1.65 0.0764 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 1.07 0.923 – 1.25 0.357 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 1.04 0.995 – 1.08 0.0832 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 1.04 0.973 – 1.11 0.249 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.11 0.991 – 1.25 0.0717 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 1.04 0.926 – 1.17 0.503 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 1.02 0.961 – 1.07 0.573 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.05 0.97 – 1.13 0.228 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.02 0.966 – 1.07 0.508 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 1.04 0.808 – 1.35 0.742 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 1.01 0.962 – 1.07 0.609 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.05 0.976 – 1.12 0.205 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.03 0.962 – 1.11 0.377 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 0.998 0.788 – 1.26 0.986 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 1.04 0.988 – 1.09 0.132 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.04 0.962 – 1.12 0.331 720 7210 all phecode
613.5 Mastodynia Genitourinary 0.892 0.707 – 1.13 0.335 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 1.06 0.983 – 1.15 0.127 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 1.09 0.981 – 1.22 0.107 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 0.941 0.815 – 1.09 0.405 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.02 0.997 – 1.05 0.0853 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.04 0.996 – 1.08 0.0806 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.07 0.999 – 1.15 0.0524 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.973 0.757 – 1.25 0.834 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.15 1.04 – 1.27 0.00729 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.994 0.89 – 1.11 0.917 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.961 0.849 – 1.09 0.524 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.997 0.958 – 1.04 0.888 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.985 0.931 – 1.04 0.6 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.958 0.869 – 1.06 0.382 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.05 0.972 – 1.13 0.23 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.03 0.906 – 1.17 0.653 274 2737 all phecode
615 Endometriosis Genitourinary 0.992 0.961 – 1.02 0.631 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.04 0.924 – 1.18 0.499 304 3037 all phecode
618 Genital prolapse Genitourinary 1.01 0.987 – 1.03 0.53 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 0.999 0.975 – 1.02 0.938 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.02 0.988 – 1.04 0.267 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.967 0.883 – 1.06 0.478 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.03 0.955 – 1.12 0.404 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 1.01 0.984 – 1.03 0.625 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.01 0.931 – 1.09 0.892 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1.01 0.971 – 1.04 0.729 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.993 0.956 – 1.03 0.718 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.993 0.945 – 1.04 0.781 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1 0.946 – 1.06 0.961 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 0.948 0.748 – 1.2 0.657 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 0.98 0.922 – 1.04 0.519 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 0.998 0.978 – 1.02 0.835 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 1 0.979 – 1.03 0.892 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.978 0.944 – 1.01 0.208 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 1 0.946 – 1.06 0.941 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 0.925 0.859 – 0.995 0.0373 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.927 0.81 – 1.06 0.271 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.925 0.839 – 1.02 0.118 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 0.983 0.957 – 1.01 0.217 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.991 0.954 – 1.03 0.657 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 1.01 0.957 – 1.08 0.637 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.999 0.983 – 1.02 0.944 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.998 0.98 – 1.02 0.79 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.996 0.821 – 1.21 0.971 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 0.999 0.979 – 1.02 0.949 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 0.985 0.941 – 1.03 0.529 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 1.01 0.98 – 1.05 0.453 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 0.989 0.942 – 1.04 0.668 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 1.02 0.87 – 1.2 0.808 159 1587 all phecode
626.8 Infertility, female Genitourinary 1.05 0.991 – 1.11 0.103 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.998 0.978 – 1.02 0.874 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 1 0.978 – 1.02 0.972 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 1.1 0.945 – 1.27 0.224 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.96 0.903 – 1.02 0.194 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 1.04 0.923 – 1.17 0.533 310 3097 all phecode
628 Ovarian cyst Genitourinary 1 0.975 – 1.03 0.788 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1 0.973 – 1.03 0.918 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.999 0.941 – 1.06 0.975 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.996 0.892 – 1.11 0.95 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1 0.959 – 1.05 0.855 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.02 0.953 – 1.09 0.548 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.977 0.922 – 1.03 0.415 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.01 0.964 – 1.05 0.793 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.984 0.906 – 1.07 0.696 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.02 0.961 – 1.09 0.484 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 1.09 0.866 – 1.37 0.464 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.05 0.99 – 1.12 0.101 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.04 0.924 – 1.17 0.527 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.17 1.02 – 1.34 0.0272 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.15 0.976 – 1.35 0.0949 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.02 0.964 – 1.08 0.476 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.974 0.933 – 1.02 0.241 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.06 0.834 – 1.35 0.635 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.04 0.921 – 1.18 0.52 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1 0.833 – 1.2 0.994 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.966 0.835 – 1.12 0.643 193 1922 all phecode
650 Normal delivery Pregnancy Complications 1.04 0.992 – 1.09 0.108 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 0.921 0.825 – 1.03 0.139 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.955 0.909 – 1 0.0673 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1 0.952 – 1.06 0.863 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 0.931 0.744 – 1.16 0.529 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.973 0.942 – 1 0.0886 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.02 0.843 – 1.24 0.823 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.989 0.946 – 1.03 0.605 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 1 0.917 – 1.09 0.999 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.994 0.965 – 1.02 0.671 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.02 0.976 – 1.06 0.423 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.947 0.813 – 1.1 0.482 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1 0.883 – 1.13 0.988 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.939 0.731 – 1.21 0.621 63 624 all phecode
679 Complications of in utero procedures Dermatologic 0.821 0.626 – 1.08 0.157 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.02 0.997 – 1.05 0.0889 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.04 0.956 – 1.14 0.354 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.02 0.934 – 1.12 0.622 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.02 0.99 – 1.05 0.198 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.02 0.989 – 1.05 0.226 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.02 0.987 – 1.04 0.282 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.04 0.954 – 1.13 0.396 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 0.969 0.915 – 1.03 0.276 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.07 1.03 – 1.12 0.00153 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 1 0.92 – 1.09 0.968 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 0.963 0.865 – 1.07 0.485 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1.06 0.969 – 1.16 0.209 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.955 0.913 – 0.998 0.0412 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 0.984 0.872 – 1.11 0.8 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 1.1 0.897 – 1.36 0.348 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.03 0.989 – 1.07 0.161 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.01 0.98 – 1.03 0.639 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 1.11 0.869 – 1.41 0.414 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 1.11 0.843 – 1.45 0.463 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 0.96 0.798 – 1.16 0.667 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 1.05 0.982 – 1.12 0.163 986 9854 all phecode
694.1 Vitiligo Dermatologic 1.1 0.853 – 1.41 0.469 60 599 all phecode
694.2 Other dyschromia Dermatologic 1.04 0.965 – 1.12 0.311 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 1.09 0.899 – 1.32 0.387 117 1170 all phecode
695 Erythematous conditions Dermatologic 1.02 0.982 – 1.07 0.264 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 1.09 0.898 – 1.33 0.373 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 1.19 1 – 1.41 0.0506 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 1.09 0.835 – 1.43 0.521 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.35 1.07 – 1.71 0.0117 73 727 all phecode
695.3 Rosacea Dermatologic 0.936 0.831 – 1.05 0.28 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.05 0.951 – 1.16 0.333 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.03 0.864 – 1.24 0.717 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.1 0.982 – 1.22 0.102 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 1.03 0.953 – 1.1 0.496 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 1 0.879 – 1.15 0.955 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 1.07 0.851 – 1.34 0.575 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.03 0.937 – 1.13 0.531 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 1.02 0.981 – 1.07 0.277 2252 22509 all phecode
696.4 Psoriasis Dermatologic 1.03 0.983 – 1.07 0.238 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.03 0.979 – 1.08 0.256 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.05 0.969 – 1.13 0.24 706 7052 all phecode
697 Sarcoidosis Dermatologic 0.961 0.88 – 1.05 0.386 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 1.03 0.96 – 1.11 0.393 782 7814 all phecode
700 Corns and callosities Dermatologic 0.968 0.856 – 1.09 0.601 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.03 0.995 – 1.06 0.0984 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 1.17 0.939 – 1.46 0.161 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.05 1.01 – 1.09 0.0263 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.19 0.928 – 1.53 0.17 61 610 all phecode
701.4 Keloid scar Dermatologic 1.08 0.946 – 1.24 0.247 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.09 0.984 – 1.2 0.102 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 0.987 0.808 – 1.21 0.902 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.01 0.986 – 1.04 0.35 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 1.02 0.983 – 1.07 0.255 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 1.01 0.97 – 1.05 0.717 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 0.96 0.861 – 1.07 0.468 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 0.99 0.926 – 1.06 0.758 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 1.04 1.01 – 1.07 0.00984 5267 52727 all phecode
704.1 Alopecia Dermatologic 1.07 0.895 – 1.29 0.448 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.01 0.797 – 1.28 0.943 76 759 all phecode
705 Disorders of sweat glands Dermatologic 0.932 0.813 – 1.07 0.307 228 2287 all phecode
705.3 Hidradenitis Dermatologic 0.914 0.787 – 1.06 0.239 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 1.05 0.964 – 1.14 0.263 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 1.02 0.995 – 1.04 0.131 8317 83195 all phecode
706.1 Acne Dermatologic 1.27 1.01 – 1.59 0.0416 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 1.01 0.992 – 1.04 0.22 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 0.99 0.945 – 1.04 0.683 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 0.96 0.896 – 1.03 0.235 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.99 0.956 – 1.02 0.558 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 0.965 0.883 – 1.06 0.437 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 0.962 0.824 – 1.12 0.625 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.11 0.872 – 1.43 0.387 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.999 0.96 – 1.04 0.964 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.06 0.973 – 1.15 0.185 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 1.04 0.957 – 1.14 0.334 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.03 0.893 – 1.2 0.656 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.04 0.943 – 1.16 0.404 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.06 0.957 – 1.17 0.268 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.1 0.985 – 1.24 0.0878 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 1 0.804 – 1.25 0.976 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.04 0.878 – 1.23 0.658 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.28 0.996 – 1.65 0.0533 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.03 0.997 – 1.06 0.0772 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.03 1 – 1.07 0.0313 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.983 0.935 – 1.03 0.501 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.976 0.811 – 1.17 0.793 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.02 0.94 – 1.11 0.631 618 6177 all phecode
716 Other arthropathies Musculoskeletal 1.01 1 – 1.02 0.045 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.02 0.982 – 1.05 0.351 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.01 0.997 – 1.03 0.115 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.01 0.999 – 1.02 0.0874 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.04 0.98 – 1.11 0.193 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 0.992 0.959 – 1.03 0.628 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1.01 0.982 – 1.03 0.665 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.995 0.967 – 1.02 0.757 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.956 0.823 – 1.11 0.553 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.02 0.911 – 1.13 0.783 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 1.02 1 – 1.04 0.0523 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.941 0.857 – 1.03 0.2 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.99 0.952 – 1.03 0.622 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 0.877 0.688 – 1.12 0.294 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.01 0.977 – 1.04 0.613 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 1.01 0.92 – 1.1 0.868 517 5173 all phecode
723.1 Torticollis Musculoskeletal 1.11 0.913 – 1.36 0.289 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.05 0.999 – 1.09 0.0569 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 0.979 0.885 – 1.08 0.679 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 0.987 0.892 – 1.09 0.797 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 0.924 0.717 – 1.19 0.539 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.07 1.01 – 1.12 0.0117 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1 0.986 – 1.02 0.722 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 0.995 0.975 – 1.02 0.671 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 1 0.898 – 1.12 0.972 334 3336 all phecode
726.3 Bursitis Musculoskeletal 0.949 0.884 – 1.02 0.15 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1 0.978 – 1.03 0.873 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.995 0.957 – 1.03 0.8 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 0.924 0.755 – 1.13 0.445 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1 0.966 – 1.04 0.884 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 0.977 0.898 – 1.06 0.592 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.984 0.883 – 1.1 0.773 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.98 0.825 – 1.16 0.817 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.993 0.96 – 1.03 0.677 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.938 0.847 – 1.04 0.227 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 0.986 0.953 – 1.02 0.392 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.996 0.962 – 1.03 0.828 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.01 0.981 – 1.04 0.565 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.05 0.979 – 1.12 0.183 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 0.975 0.799 – 1.19 0.803 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.02 0.896 – 1.15 0.814 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.02 0.898 – 1.16 0.746 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 0.926 0.84 – 1.02 0.122 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.931 0.804 – 1.08 0.337 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.884 0.678 – 1.15 0.365 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.03 0.977 – 1.08 0.315 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 1.07 0.947 – 1.2 0.288 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.999 0.914 – 1.09 0.981 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 0.771 0.64 – 0.93 0.00659 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1 0.947 – 1.07 0.876 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 1.04 0.859 – 1.26 0.69 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 1.01 0.987 – 1.03 0.476 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 0.955 0.823 – 1.11 0.548 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 0.993 0.964 – 1.02 0.618 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 1 0.956 – 1.05 0.947 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 0.984 0.933 – 1.04 0.549 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.02 0.998 – 1.05 0.0657 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 1.02 0.965 – 1.07 0.545 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 0.991 0.873 – 1.13 0.888 248 2476 all phecode
737 Curvature of spine Musculoskeletal 0.965 0.908 – 1.03 0.264 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.978 0.918 – 1.04 0.484 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.999 0.953 – 1.05 0.965 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.01 0.958 – 1.07 0.702 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 1.04 0.946 – 1.14 0.433 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 1.01 0.993 – 1.02 0.353 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.997 0.981 – 1.01 0.684 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.981 0.96 – 1 0.0849 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.08 0.964 – 1.2 0.19 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.978 0.899 – 1.06 0.611 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.01 0.994 – 1.03 0.192 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.01 0.974 – 1.04 0.652 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 1.09 0.889 – 1.34 0.408 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 1.03 0.946 – 1.12 0.518 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 0.94 0.798 – 1.11 0.457 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 1.05 0.992 – 1.11 0.0931 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 0.835 0.684 – 1.02 0.074 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 1.01 0.766 – 1.34 0.936 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.963 0.926 – 1 0.0536 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 0.943 0.844 – 1.05 0.306 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.761 0.615 – 0.94 0.0113 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 0.922 0.84 – 1.01 0.0859 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 0.983 0.938 – 1.03 0.464 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.02 0.996 – 1.04 0.11 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 1.02 0.993 – 1.05 0.145 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 1.01 0.987 – 1.04 0.307 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1.07 0.982 – 1.17 0.121 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 1.08 0.986 – 1.18 0.0983 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.02 0.946 – 1.09 0.636 815 8144 all phecode
745 Pain in joint Musculoskeletal 1.01 0.992 – 1.04 0.213 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.02 0.977 – 1.06 0.431 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.02 0.982 – 1.06 0.29 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.918 0.843 – 0.999 0.0472 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.958 0.838 – 1.09 0.522 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.06 1.01 – 1.11 0.0182 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.999 0.851 – 1.17 0.992 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.17 0.88 – 1.55 0.282 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.01 0.903 – 1.14 0.809 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.969 0.895 – 1.05 0.431 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.92 0.82 – 1.03 0.152 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.978 0.845 – 1.13 0.764 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1 0.902 – 1.12 0.93 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.01 0.883 – 1.16 0.872 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.995 0.82 – 1.21 0.957 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.977 0.927 – 1.03 0.395 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.955 0.884 – 1.03 0.25 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.941 0.855 – 1.04 0.219 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.916 0.799 – 1.05 0.206 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1 0.933 – 1.08 0.956 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.969 0.878 – 1.07 0.537 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.01 0.898 – 1.12 0.93 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.977 0.876 – 1.09 0.673 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 1.01 0.889 – 1.14 0.911 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 0.998 0.869 – 1.15 0.981 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.888 0.712 – 1.11 0.293 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.05 0.873 – 1.26 0.601 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.15 0.911 – 1.45 0.24 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.09 0.895 – 1.33 0.386 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.987 0.893 – 1.09 0.796 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.99 0.86 – 1.14 0.89 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.981 0.836 – 1.15 0.819 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.968 0.798 – 1.18 0.746 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.01 0.927 – 1.1 0.84 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.09 0.876 – 1.35 0.445 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1 0.907 – 1.11 0.958 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.991 0.84 – 1.17 0.911 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.07 0.845 – 1.36 0.561 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.859 0.746 – 0.989 0.0341 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.904 0.732 – 1.12 0.346 96 959 all phecode
760 Back pain Symptoms 0.991 0.972 – 1.01 0.358 11126 111353 all phecode
761 Cervicalgia Symptoms 1.06 1.01 – 1.12 0.0141 1791 17901 all phecode
764 Sciatica Symptoms 1.02 0.978 – 1.06 0.36 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.01 0.952 – 1.07 0.717 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 1.02 0.944 – 1.11 0.558 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.945 0.881 – 1.01 0.118 870 8687 all phecode
771.1 Swelling of limb Symptoms 1 0.972 – 1.03 0.872 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 1.02 0.938 – 1.1 0.678 659 6581 all phecode
773 Pain in limb Symptoms 0.993 0.967 – 1.02 0.607 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 1.07 0.918 – 1.25 0.377 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.04 0.997 – 1.1 0.069 1870 18715 all phecode
782.3 Edema Symptoms 1.04 0.985 – 1.09 0.175 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 0.977 0.835 – 1.14 0.771 175 1748 all phecode
783 Fever of unknown origin Symptoms 1.01 0.977 – 1.04 0.559 3911 39105 all phecode
785 Abdominal pain Symptoms 0.998 0.987 – 1.01 0.67 40080 301686 all phecode
788 Syncope and collapse Symptoms 0.986 0.965 – 1.01 0.204 9069 90813 all phecode
789 Nausea and vomiting Symptoms 0.991 0.972 – 1.01 0.34 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 0.949 0.809 – 1.11 0.526 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 1.02 0.82 – 1.27 0.857 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.02 0.991 – 1.04 0.214 6357 63635 all phecode
791 Gangrene Symptoms 1.02 0.937 – 1.12 0.6 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.811 0.656 – 1 0.054 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.897 0.752 – 1.07 0.23 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 0.985 0.904 – 1.07 0.739 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.977 0.808 – 1.18 0.81 120 1198 all phecode
797 Shock Symptoms 0.974 0.827 – 1.15 0.752 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 0.957 0.781 – 1.17 0.672 102 1020 all phecode
798 Malaise and fatigue Symptoms 0.969 0.936 – 1 0.0826 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 1 0.92 – 1.09 0.959 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 1.04 1.02 – 1.07 0.00154 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.04 0.995 – 1.1 0.0768 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.887 0.755 – 1.04 0.143 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.07 1.02 – 1.12 0.00242 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 1.04 0.968 – 1.12 0.27 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.07 1.02 – 1.11 0.00427 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.07 1.02 – 1.12 0.00529 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.949 0.878 – 1.02 0.181 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 1.03 1 – 1.05 0.023 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.01 0.959 – 1.06 0.764 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.02 0.987 – 1.04 0.294 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.07 1.01 – 1.13 0.0137 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 1 0.969 – 1.04 0.807 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.06 1 – 1.12 0.0504 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 1.04 0.967 – 1.12 0.295 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.07 1.01 – 1.14 0.0147 1300 12998 all phecode
817 Concussion Injuries & Poisonings 0.946 0.827 – 1.08 0.414 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.09 0.996 – 1.19 0.0603 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.02 0.984 – 1.06 0.261 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 1.06 1.01 – 1.12 0.0232 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 0.991 0.947 – 1.04 0.694 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 1 0.986 – 1.02 0.77 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.03 0.94 – 1.13 0.54 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 1.03 0.937 – 1.13 0.536 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.998 0.971 – 1.03 0.912 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.09 0.919 – 1.29 0.324 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.07 0.978 – 1.18 0.136 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.988 0.941 – 1.04 0.609 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.978 0.923 – 1.04 0.453 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.02 0.98 – 1.05 0.376 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.01 0.97 – 1.04 0.755 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1.13 0.887 – 1.45 0.315 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.05 1.02 – 1.09 0.00441 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.13 1 – 1.28 0.0493 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 1.12 0.969 – 1.3 0.125 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.04 1 – 1.08 0.0377 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.03 0.89 – 1.18 0.728 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 1.06 0.819 – 1.37 0.655 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.01 0.977 – 1.04 0.569 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.893 0.67 – 1.19 0.441 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.996 0.806 – 1.23 0.971 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.07 0.913 – 1.24 0.422 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 0.988 0.898 – 1.09 0.807 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 1.2 1.05 – 1.37 0.00893 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.1 0.941 – 1.28 0.235 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.05 0.891 – 1.23 0.583 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 0.959 0.906 – 1.01 0.148 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.02 0.984 – 1.05 0.342 4260 42663 all phecode
916 Contusion Injuries & Poisonings 1.06 1 – 1.12 0.0424 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.969 0.829 – 1.13 0.695 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.963 0.867 – 1.07 0.483 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.989 0.87 – 1.12 0.87 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.993 0.95 – 1.04 0.765 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.08 0.94 – 1.24 0.274 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.935 0.767 – 1.14 0.511 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.977 0.895 – 1.07 0.608 550 5509 all phecode
947 Urticaria Injuries & Poisonings 0.964 0.869 – 1.07 0.494 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 1 0.901 – 1.11 0.995 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.16 1.05 – 1.29 0.00317 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.03 0.908 – 1.16 0.681 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.01 0.916 – 1.1 0.906 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.02 0.775 – 1.34 0.894 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.909 0.715 – 1.15 0.433 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.01 0.992 – 1.02 0.373 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.01 0.991 – 1.02 0.404 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.01 0.918 – 1.12 0.785 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.967 0.902 – 1.04 0.335 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.03 0.93 – 1.15 0.529 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.06 0.949 – 1.18 0.314 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.11 0.966 – 1.27 0.141 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.941 0.833 – 1.06 0.326 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.952 0.842 – 1.08 0.428 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.01 0.981 – 1.03 0.577 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.02 0.962 – 1.09 0.481 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.04 0.949 – 1.14 0.394 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.01 0.916 – 1.12 0.775 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.11 1.02 – 1.22 0.0194 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.977 0.897 – 1.06 0.598 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.03 0.986 – 1.08 0.173 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.14 0.986 – 1.33 0.0756 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.06 0.941 – 1.2 0.326 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.934 0.752 – 1.16 0.535 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1 0.828 – 1.22 0.971 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.896 0.731 – 1.1 0.287 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.835 0.654 – 1.07 0.149 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.974 0.745 – 1.27 0.849 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.08 0.948 – 1.24 0.241 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.02 0.942 – 1.1 0.64 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.03 0.891 – 1.19 0.684 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.04 0.809 – 1.33 0.768 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 0.987 0.796 – 1.22 0.902 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.913 0.746 – 1.12 0.374 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.895 0.72 – 1.11 0.317 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 0.982 0.946 – 1.02 0.331 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 0.973 0.937 – 1.01 0.159 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 0.973 0.937 – 1.01 0.159 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 0.993 0.97 – 1.02 0.564 7467 77440 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 0.987 0.945 – 1.03 0.541 2298 23863 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.96 0.879 – 1.05 0.362 524 5780 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 0.997 0.923 – 1.08 0.948 704 7587 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 0.948 0.7 – 1.28 0.73 42 488 exclusion phecode
010 Tuberculosis Infectious Diseases 1.02 0.86 – 1.21 0.83 136 1473 exclusion phecode
038 Septicemia Infectious Diseases 0.988 0.955 – 1.02 0.514 3492 37166 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 0.983 0.911 – 1.06 0.668 719 7639 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.03 0.93 – 1.13 0.6 411 4444 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.02 0.999 – 1.04 0.0562 10078 106125 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.03 0.994 – 1.08 0.1 2561 27918 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.04 0.986 – 1.1 0.145 1391 14570 exclusion phecode
041.4 E. coli Infectious Diseases 1.01 0.963 – 1.05 0.807 2254 23837 exclusion phecode
053 Herpes zoster Infectious Diseases 1.04 0.933 – 1.16 0.464 351 3578 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.13 0.901 – 1.42 0.293 81 834 exclusion phecode
054 Herpes simplex Infectious Diseases 1.06 0.912 – 1.24 0.439 185 1864 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.04 0.946 – 1.14 0.438 505 5347 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.02 0.783 – 1.33 0.873 55 612 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 1.03 0.849 – 1.25 0.758 113 1226 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.09 0.949 – 1.26 0.22 218 2337 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 0.944 0.823 – 1.08 0.405 226 2396 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 0.953 0.857 – 1.06 0.381 365 3750 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.04 0.87 – 1.24 0.678 128 1381 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.963 0.79 – 1.18 0.713 101 1102 exclusion phecode
078 Viral warts & HPV Infectious Diseases 1.09 1.01 – 1.17 0.0184 875 8831 exclusion phecode
079 Viral infection Infectious Diseases 0.98 0.94 – 1.02 0.352 2378 24104 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.814 0.626 – 1.06 0.126 61 573 exclusion phecode
080 Postoperative infection Infectious Diseases 1.02 0.985 – 1.05 0.281 3799 39375 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.01 0.962 – 1.05 0.776 2012 21929 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.987 0.751 – 1.3 0.925 59 623 exclusion phecode
1000 Burns Injuries & Poisonings 1.02 0.93 – 1.12 0.675 497 5192 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 1.02 0.955 – 1.08 0.591 1054 10681 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 0.988 0.959 – 1.02 0.436 4676 47977 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.02 0.899 – 1.16 0.73 245 2649 exclusion phecode
1005 Other symptoms Injuries & Poisonings 0.994 0.937 – 1.05 0.831 1216 12644 exclusion phecode
1006 Crushing injury Injuries & Poisonings 1.02 0.898 – 1.17 0.72 237 2351 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 1.09 0.953 – 1.25 0.207 230 2349 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.04 0.973 – 1.12 0.244 894 9187 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 1.02 0.996 – 1.05 0.0994 7438 75915 exclusion phecode
1010 Other tests Injuries & Poisonings 1 0.975 – 1.03 0.798 5057 52193 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.01 0.99 – 1.04 0.268 7774 80583 exclusion phecode
1012 Late effect Injuries & Poisonings 1.07 0.875 – 1.31 0.508 95 943 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.06 0.936 – 1.2 0.357 271 2826 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.11 0.854 – 1.44 0.443 58 602 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 1.04 1.01 – 1.08 0.0199 3575 37074 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.01 0.99 – 1.03 0.421 13517 139544 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.04 0.91 – 1.18 0.586 242 2532 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 1.03 0.9 – 1.17 0.692 237 2473 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.04 0.813 – 1.32 0.77 67 681 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.12 0.934 – 1.35 0.216 122 1273 exclusion phecode
112 Candidiasis Infectious Diseases 1.02 0.973 – 1.07 0.38 1772 18642 exclusion phecode
117 Mycoses Infectious Diseases 0.966 0.843 – 1.11 0.623 226 2401 exclusion phecode
117.4 Aspergillosis Infectious Diseases 0.957 0.806 – 1.14 0.615 135 1452 exclusion phecode
130 Spirochetal infection Infectious Diseases 1.15 0.917 – 1.45 0.223 73 711 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 0.961 0.734 – 1.26 0.769 62 621 exclusion phecode
134 Helminthiases Infectious Diseases 1.16 0.959 – 1.4 0.127 107 1100 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.18 0.956 – 1.46 0.122 90 926 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.995 0.852 – 1.16 0.951 177 1818 exclusion phecode
145 Cancer of mouth Neoplasms 0.996 0.912 – 1.09 0.925 546 5695 exclusion phecode
145.2 Cancer of tongue Neoplasms 0.871 0.769 – 0.986 0.0287 274 2766 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 1.08 0.867 – 1.34 0.5 86 928 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.04 0.778 – 1.39 0.798 49 478 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.05 0.959 – 1.14 0.314 552 5733 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.03 0.9 – 1.18 0.654 221 2282 exclusion phecode
149.4 Cancer of larynx Neoplasms 0.954 0.833 – 1.09 0.49 231 2401 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.19 0.904 – 1.57 0.214 52 506 exclusion phecode
150 Cancer of esophagus Neoplasms 0.971 0.897 – 1.05 0.464 681 6837 exclusion phecode
151 Cancer of stomach Neoplasms 0.935 0.853 – 1.03 0.156 504 5090 exclusion phecode
153 Colorectal cancer Neoplasms 0.993 0.961 – 1.03 0.668 4052 40692 exclusion phecode
153.2 Colon cancer Neoplasms 0.982 0.944 – 1.02 0.374 2763 27523 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.993 0.947 – 1.04 0.778 1900 19330 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.03 0.925 – 1.15 0.564 339 3531 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.19 0.996 – 1.42 0.056 129 1400 exclusion phecode
157 Pancreatic cancer Neoplasms 0.959 0.879 – 1.05 0.346 565 5803 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.968 0.904 – 1.04 0.356 920 9366 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1 0.97 – 1.03 0.975 4871 49299 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.915 0.787 – 1.06 0.247 173 1696 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.914 0.781 – 1.07 0.26 173 1791 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.06 0.9 – 1.24 0.508 165 1636 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 1.02 0.778 – 1.34 0.889 52 531 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.02 0.974 – 1.06 0.469 2439 24995 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1 0.954 – 1.05 0.989 1912 19661 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 0.932 0.839 – 1.03 0.184 391 3887 exclusion phecode
170.1 Bone cancer Neoplasms 0.86 0.713 – 1.04 0.116 119 1179 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 0.946 0.84 – 1.07 0.364 295 2937 exclusion phecode
172 Skin cancer Neoplasms 1 0.981 – 1.02 0.982 11779 118841 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.986 0.945 – 1.03 0.504 2345 23491 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.987 0.946 – 1.03 0.542 2375 23769 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1.01 0.985 – 1.03 0.591 9594 97052 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.972 0.891 – 1.06 0.514 566 5868 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.932 0.791 – 1.1 0.402 152 1601 exclusion phecode
174 Breast cancer Neoplasms 1.01 0.993 – 1.03 0.203 10477 105842 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1.01 0.99 – 1.03 0.304 10299 103976 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.01 0.989 – 1.03 0.381 9700 98142 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.14 0.929 – 1.39 0.215 97 951 exclusion phecode
175 Acquired absence of breast Neoplasms 1.02 0.978 – 1.07 0.306 1941 20043 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.01 0.967 – 1.06 0.558 1802 18231 exclusion phecode
180.1 Cervical cancer Neoplasms 1.04 0.911 – 1.2 0.536 228 2276 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.01 0.962 – 1.06 0.674 1715 17390 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 1.02 0.96 – 1.09 0.486 1068 10772 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.03 0.973 – 1.1 0.28 1134 11463 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.02 0.946 – 1.09 0.638 795 8016 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.03 0.953 – 1.1 0.498 770 7802 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.16 1.02 – 1.32 0.027 248 2545 exclusion phecode
185 Cancer of prostate Neoplasms 1.03 1.01 – 1.06 0.0181 5516 54408 exclusion phecode
187 Cancer of other male genital organs Neoplasms 0.944 0.855 – 1.04 0.255 416 4184 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.899 0.699 – 1.16 0.407 65 658 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.967 0.852 – 1.1 0.598 264 2684 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.99 0.812 – 1.21 0.921 103 1011 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.01 0.976 – 1.05 0.567 3571 37458 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1 0.935 – 1.08 0.938 861 9629 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.01 0.936 – 1.08 0.89 826 9274 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.888 0.685 – 1.15 0.373 60 588 exclusion phecode
189.2 Cancer of bladder Neoplasms 0.997 0.953 – 1.04 0.905 2114 21788 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.982 0.936 – 1.03 0.457 1874 19403 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.839 0.695 – 1.01 0.0658 119 1293 exclusion phecode
190 Cancer of eye Neoplasms 1.01 0.854 – 1.18 0.947 153 1533 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.08 0.991 – 1.17 0.0817 610 6133 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 1.06 0.972 – 1.17 0.179 507 5022 exclusion phecode
191.11 Cancer of brain Neoplasms 1.05 0.951 – 1.15 0.359 470 4660 exclusion phecode
193 Thyroid cancer Neoplasms 1.17 1.03 – 1.31 0.0124 291 2978 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 0.885 0.708 – 1.1 0.279 79 854 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.02 1 – 1.04 0.0157 14705 146303 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.02 1 – 1.04 0.0146 14099 141059 exclusion phecode
197 Chemotherapy Neoplasms 1 0.985 – 1.02 0.965 18220 186146 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 0.997 0.974 – 1.02 0.781 8210 83581 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1 0.972 – 1.03 0.883 4623 46616 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.962 0.918 – 1.01 0.104 1958 20046 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.99 0.936 – 1.05 0.735 1310 13457 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 0.981 0.94 – 1.02 0.385 2288 23573 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1 0.927 – 1.08 0.992 717 7468 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1 0.956 – 1.05 0.895 1869 19118 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.02 0.868 – 1.2 0.79 152 1669 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.08 1.02 – 1.14 0.0134 1203 12571 exclusion phecode
199.4 Neurofibromatosis Neoplasms 0.939 0.736 – 1.2 0.616 72 824 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.05 0.975 – 1.12 0.214 835 8816 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.08 0.958 – 1.21 0.218 310 3507 exclusion phecode
201 Hodgkin's disease Neoplasms 0.935 0.816 – 1.07 0.33 225 2311 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.952 0.909 – 0.998 0.0405 1949 20174 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.944 0.896 – 0.995 0.0312 1567 16064 exclusion phecode
202.21 Nodular lymphoma Neoplasms 0.941 0.837 – 1.06 0.306 318 3236 exclusion phecode
202.24 Large cell lymphoma Neoplasms 0.963 0.878 – 1.06 0.421 516 5177 exclusion phecode
204 Leukemia Neoplasms 0.965 0.914 – 1.02 0.206 1444 14828 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 0.918 0.837 – 1.01 0.0676 505 5175 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.889 0.656 – 1.21 0.449 46 497 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.91 0.826 – 1 0.0588 450 4556 exclusion phecode
204.2 Myeloid leukemia Neoplasms 0.974 0.879 – 1.08 0.613 405 4115 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.979 0.868 – 1.1 0.733 286 2933 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.977 0.811 – 1.18 0.805 127 1257 exclusion phecode
204.4 Multiple myeloma Neoplasms 0.954 0.867 – 1.05 0.338 475 4980 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1 0.987 – 1.02 0.736 17373 170297 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.08 1 – 1.16 0.0456 833 8584 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.01 0.981 – 1.04 0.468 4561 45541 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.922 0.821 – 1.04 0.175 308 3061 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.08 0.954 – 1.22 0.23 273 2793 exclusion phecode
214 Lipoma Neoplasms 1.01 0.981 – 1.04 0.565 5554 55333 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.01 0.976 – 1.04 0.612 4060 40546 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.919 0.86 – 0.983 0.0134 968 9648 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.997 0.972 – 1.02 0.802 6641 66839 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.944 0.864 – 1.03 0.198 550 5516 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.936 0.856 – 1.02 0.153 518 5196 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.989 0.967 – 1.01 0.333 8222 83780 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.988 0.966 – 1.01 0.308 8395 85545 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.03 0.915 – 1.17 0.593 285 2970 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.99 0.933 – 1.05 0.753 1207 12125 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.954 0.819 – 1.11 0.546 185 1862 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.909 0.765 – 1.08 0.28 145 1482 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1 0.852 – 1.18 0.96 146 1539 exclusion phecode
224 Benign neoplasm of eye Neoplasms 1.02 0.838 – 1.25 0.817 104 1131 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.944 0.709 – 1.26 0.691 53 588 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.03 0.956 – 1.12 0.399 678 7104 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.03 0.948 – 1.11 0.508 644 6748 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.07 0.809 – 1.4 0.651 50 511 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.02 0.888 – 1.16 0.811 229 2259 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.04 0.962 – 1.12 0.335 706 7425 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.06 0.897 – 1.26 0.485 148 1628 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.04 0.932 – 1.17 0.451 309 3134 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1 0.88 – 1.14 0.998 256 2741 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.02 0.964 – 1.08 0.505 1386 13970 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.995 0.95 – 1.04 0.816 2070 20663 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.02 0.934 – 1.12 0.633 506 5098 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.05 0.977 – 1.12 0.201 934 9463 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.998 0.899 – 1.11 0.965 405 4019 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.03 0.948 – 1.13 0.453 565 5788 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.04 0.986 – 1.1 0.146 1524 15859 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.949 0.853 – 1.06 0.333 374 3872 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.18 0.934 – 1.49 0.164 68 780 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.82 0.675 – 0.994 0.0438 112 1163 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.01 0.987 – 1.02 0.543 12430 123360 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.992 0.927 – 1.06 0.806 915 9429 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.985 0.793 – 1.22 0.893 91 861 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.01 0.987 – 1.03 0.523 11869 118095 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.896 0.785 – 1.02 0.102 236 2414 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.887 0.761 – 1.03 0.122 181 1823 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.9 0.771 – 1.05 0.179 175 1755 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.05 0.943 – 1.18 0.356 343 3388 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1 0.985 – 1.02 0.912 16560 166135 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.984 0.942 – 1.03 0.476 2166 24694 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.951 0.819 – 1.11 0.517 176 2114 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.29 0.933 – 1.8 0.123 35 681 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.992 0.889 – 1.11 0.88 350 4233 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.05 0.865 – 1.28 0.609 106 1428 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1 0.986 – 1.02 0.755 14903 152174 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.984 0.778 – 1.24 0.891 80 944 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.02 0.828 – 1.25 0.869 91 1836 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.994 0.923 – 1.07 0.868 747 8937 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.01 0.905 – 1.12 0.902 358 4573 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1 0.918 – 1.09 0.971 569 6072 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.972 0.848 – 1.11 0.685 228 2348 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.04 0.929 – 1.16 0.503 342 3712 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.02 0.844 – 1.24 0.817 113 1129 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.02 0.898 – 1.16 0.769 246 3152 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.983 0.924 – 1.05 0.602 1023 11912 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.03 0.956 – 1.11 0.433 729 8411 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.02 0.937 – 1.1 0.705 639 7478 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.991 0.91 – 1.08 0.834 569 6712 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.12 0.915 – 1.37 0.275 97 1217 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.01 0.925 – 1.1 0.854 549 6019 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.17 1 – 1.37 0.0497 155 1621 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.12 0.901 – 1.39 0.308 77 841 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.992 0.862 – 1.14 0.914 219 2330 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.941 0.732 – 1.21 0.632 63 799 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.868 0.724 – 1.04 0.127 119 1395 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.07 0.978 – 1.17 0.138 517 5565 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.09 0.921 – 1.3 0.308 139 1562 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.03 0.817 – 1.3 0.803 74 894 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.18 0.921 – 1.52 0.188 65 672 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.09 0.97 – 1.23 0.147 301 3148 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.09 0.968 – 1.23 0.157 300 3139 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 1.15 0.993 – 1.32 0.0623 204 2044 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.13 0.968 – 1.32 0.121 173 1788 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 0.998 0.843 – 1.18 0.982 147 1512 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.05 0.881 – 1.24 0.609 140 1430 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.983 0.784 – 1.23 0.88 79 917 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.876 0.728 – 1.05 0.163 123 1279 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.878 0.75 – 1.03 0.107 173 1774 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.17 0.867 – 1.57 0.307 43 465 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.01 0.94 – 1.1 0.705 699 7303 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 0.987 0.924 – 1.05 0.684 1004 10489 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1 0.922 – 1.09 0.983 637 6648 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.964 0.866 – 1.07 0.507 370 3848 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.827 0.644 – 1.06 0.135 64 651 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.982 0.852 – 1.13 0.804 200 2079 exclusion phecode
269 Proteinuria Endocrine/metabolic 0.859 0.754 – 0.978 0.0216 250 3027 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.93 0.815 – 1.06 0.277 238 2652 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.94 0.815 – 1.08 0.396 206 2291 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 0.911 0.768 – 1.08 0.28 144 1662 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 0.969 0.783 – 1.2 0.772 90 978 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.04 0.805 – 1.35 0.752 62 602 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.24 1.04 – 1.47 0.0149 142 1398 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.26 1.05 – 1.51 0.0126 129 1219 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.01 0.999 – 1.02 0.0803 30331 208596 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.01 0.998 – 1.02 0.0967 30268 208396 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.01 0.999 – 1.02 0.0687 28136 202121 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.861 0.638 – 1.16 0.326 50 526 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.974 0.819 – 1.16 0.765 139 1455 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.1 0.949 – 1.27 0.207 186 1892 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.03 0.992 – 1.07 0.128 3086 33973 exclusion phecode
274.1 Gout Endocrine/metabolic 1.02 0.984 – 1.07 0.241 2597 29046 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.1 0.897 – 1.36 0.35 92 1012 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.04 0.951 – 1.14 0.384 538 5459 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.04 0.943 – 1.14 0.468 491 4972 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.05 0.997 – 1.1 0.0679 1742 18700 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 1.19 1.09 – 1.3 6.68e-05 565 5841 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.05 0.938 – 1.18 0.373 303 3331 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.963 0.902 – 1.03 0.262 968 10607 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1 0.841 – 1.19 0.996 142 1541 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.01 0.98 – 1.03 0.615 5811 64584 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1 0.965 – 1.04 0.978 3210 36279 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.13 0.974 – 1.3 0.109 196 2164 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 0.998 0.946 – 1.05 0.949 1435 16068 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 0.984 0.91 – 1.06 0.687 680 8740 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.01 0.948 – 1.07 0.835 1169 12538 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.03 0.966 – 1.11 0.344 908 10337 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.02 0.951 – 1.1 0.561 820 9381 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.1 0.892 – 1.36 0.372 94 992 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1 0.963 – 1.05 0.828 2288 24958 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.04 0.925 – 1.16 0.54 320 4034 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 0.934 0.769 – 1.13 0.49 105 1127 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 0.984 0.912 – 1.06 0.682 734 7860 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.947 0.846 – 1.06 0.348 324 3266 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.932 0.808 – 1.08 0.337 196 2063 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.929 0.678 – 1.27 0.646 41 462 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.02 0.998 – 1.04 0.0748 9157 94982 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.02 0.999 – 1.04 0.064 9021 93569 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 0.997 0.78 – 1.28 0.983 70 723 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.859 0.646 – 1.14 0.299 53 557 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.07 0.93 – 1.23 0.347 209 2216 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.01 0.864 – 1.17 0.938 178 1857 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.99 0.822 – 1.19 0.919 120 1221 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 0.977 0.853 – 1.12 0.734 221 2254 exclusion phecode
280 Iron deficiency anemias Hematopoietic 0.998 0.972 – 1.02 0.859 6349 66456 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.998 0.972 – 1.02 0.895 6112 63888 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.982 0.88 – 1.1 0.743 360 3895 exclusion phecode
281 Other deficiency anemia Hematopoietic 1 0.933 – 1.07 0.995 908 9768 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1 0.932 – 1.07 0.988 873 9374 exclusion phecode
281.11 Pernicious anemia Hematopoietic 0.993 0.913 – 1.08 0.876 616 6556 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.05 0.886 – 1.25 0.561 145 1554 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 1.03 0.866 – 1.21 0.768 149 1667 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.04 0.758 – 1.42 0.826 42 465 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 0.913 0.764 – 1.09 0.317 124 1334 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 0.971 0.723 – 1.3 0.842 46 504 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.903 0.712 – 1.14 0.398 69 748 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 0.906 0.752 – 1.09 0.303 117 1217 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.858 0.692 – 1.06 0.163 89 944 exclusion phecode
284 Aplastic anemia Hematopoietic 0.925 0.828 – 1.03 0.163 345 3908 exclusion phecode
285 Other anemias Hematopoietic 0.99 0.97 – 1.01 0.342 9875 105987 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.938 0.817 – 1.08 0.362 218 2336 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 0.971 0.881 – 1.07 0.56 451 6148 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.984 0.881 – 1.1 0.781 349 3619 exclusion phecode
286 Coagulation defects Hematopoietic 0.934 0.867 – 1.01 0.0684 764 8105 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.95 0.858 – 1.05 0.331 391 4006 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.937 0.752 – 1.17 0.564 83 859 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.952 0.837 – 1.08 0.45 248 2547 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.03 0.792 – 1.34 0.818 55 557 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.915 0.721 – 1.16 0.461 70 753 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.882 0.785 – 0.991 0.0348 308 3394 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.947 0.896 – 1 0.052 1390 14646 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.803 0.66 – 0.978 0.029 107 1155 exclusion phecode
287.2 Allergic purpura Hematopoietic 0.961 0.706 – 1.31 0.801 45 449 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 0.939 0.888 – 0.994 0.0306 1303 13740 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 0.923 0.829 – 1.03 0.14 364 3671 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.99 0.745 – 1.32 0.945 54 675 exclusion phecode
288 Diseases of white blood cells Hematopoietic 0.983 0.948 – 1.02 0.36 3217 32920 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 0.978 0.94 – 1.02 0.266 2718 27643 exclusion phecode
288.11 Neutropenia Hematopoietic 0.978 0.94 – 1.02 0.27 2723 27710 exclusion phecode
288.3 Eosinophilia Hematopoietic 0.914 0.71 – 1.18 0.486 63 630 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.976 0.904 – 1.05 0.532 715 7620 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.981 0.86 – 1.12 0.769 245 2534 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1 0.958 – 1.05 0.963 2231 22907 exclusion phecode
289.5 Diseases of spleen Hematopoietic 0.96 0.867 – 1.06 0.437 418 4588 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.03 0.898 – 1.17 0.704 238 2636 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 0.892 0.705 – 1.13 0.344 73 804 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.02 0.972 – 1.08 0.381 1573 17094 exclusion phecode
290.1 Dementias Mental Disorders 1.03 0.962 – 1.11 0.376 836 8856 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.987 0.888 – 1.1 0.815 365 3765 exclusion phecode
290.16 Vascular dementia Mental Disorders 0.878 0.747 – 1.03 0.114 158 1777 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.01 0.924 – 1.1 0.839 535 5820 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.09 0.841 – 1.41 0.523 61 648 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.05 0.973 – 1.14 0.204 695 7437 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.06 0.873 – 1.28 0.574 111 1144 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.06 0.921 – 1.21 0.434 230 2552 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.07 0.967 – 1.2 0.182 369 3880 exclusion phecode
292 Neurological disorders Mental Disorders 1.02 0.986 – 1.05 0.26 3917 41132 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.04 0.982 – 1.1 0.177 1279 13321 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 1.08 0.911 – 1.27 0.39 156 1725 exclusion phecode
292.3 Memory loss Mental Disorders 1 0.924 – 1.09 0.912 603 6240 exclusion phecode
292.4 Altered mental status Mental Disorders 1.04 0.992 – 1.09 0.102 1831 19419 exclusion phecode
292.6 Hallucinations Mental Disorders 1.07 0.942 – 1.21 0.309 263 2704 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1 0.955 – 1.05 0.953 1884 18867 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.992 0.921 – 1.07 0.839 757 7948 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.05 0.971 – 1.13 0.226 703 7497 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.08 0.983 – 1.18 0.109 487 5155 exclusion phecode
295.2 Paranoid disorders Mental Disorders 0.928 0.782 – 1.1 0.395 147 1576 exclusion phecode
295.3 Psychosis Mental Disorders 1.04 0.877 – 1.23 0.669 143 1496 exclusion phecode
296 Mood disorders Mental Disorders 1.03 1.01 – 1.05 0.0108 10454 108267 exclusion phecode
296.1 Bipolar Mental Disorders 1.07 0.995 – 1.14 0.0703 880 9349 exclusion phecode
296.2 Depression Mental Disorders 1.03 1 – 1.05 0.0162 9918 102662 exclusion phecode
296.22 Major depressive disorder Mental Disorders 0.974 0.868 – 1.09 0.654 306 3155 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.01 0.89 – 1.15 0.857 253 2654 exclusion phecode
300 Anxiety disorders Mental Disorders 1 0.974 – 1.03 0.948 5823 59785 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.01 0.978 – 1.03 0.708 5385 55154 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 0.862 0.722 – 1.03 0.102 133 1317 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.951 0.876 – 1.03 0.225 608 6133 exclusion phecode
300.13 Phobia Mental Disorders 0.983 0.889 – 1.09 0.734 420 4343 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.853 0.707 – 1.03 0.0986 119 1246 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 0.922 0.68 – 1.25 0.599 45 462 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 0.939 0.768 – 1.15 0.537 108 1100 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.18 0.96 – 1.45 0.115 99 1025 exclusion phecode
301 Personality disorders Mental Disorders 0.92 0.814 – 1.04 0.179 284 2946 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.897 0.736 – 1.09 0.282 105 1029 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 1.02 0.899 – 1.16 0.759 255 2634 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.961 0.868 – 1.06 0.441 404 4083 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.977 0.869 – 1.1 0.705 305 3046 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.857 0.703 – 1.05 0.127 102 1074 exclusion phecode
304 Adjustment reaction Mental Disorders 1.05 0.93 – 1.19 0.411 256 2598 exclusion phecode
305.2 Eating disorder Mental Disorders 1.28 1 – 1.64 0.0487 68 757 exclusion phecode
306 Other mental disorder Mental Disorders 1.02 1 – 1.03 0.0103 24337 203880 exclusion phecode
306.9 Tension headache Mental Disorders 1.05 0.928 – 1.19 0.436 268 2697 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.967 0.754 – 1.24 0.789 69 691 exclusion phecode
313.3 Autism Mental Disorders 0.953 0.71 – 1.28 0.75 50 483 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.07 0.949 – 1.2 0.284 296 3134 exclusion phecode
315.1 Learning disorder Mental Disorders 1.02 0.851 – 1.23 0.821 130 1452 exclusion phecode
315.2 Speech and language disorder Mental Disorders 1.05 0.835 – 1.32 0.671 78 767 exclusion phecode
316 Substance addiction and disorders Mental Disorders 0.995 0.966 – 1.03 0.767 4539 48314 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.03 0.771 – 1.37 0.85 48 527 exclusion phecode
317 Alcohol-related disorders Mental Disorders 0.982 0.963 – 1 0.0747 11052 114121 exclusion phecode
317.1 Alcoholism Mental Disorders 0.977 0.955 – 1 0.0529 7765 79961 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 0.957 0.884 – 1.04 0.289 654 7680 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.02 1.01 – 1.04 0.00547 16528 165190 exclusion phecode
320 Meningitis Neurological 0.972 0.876 – 1.08 0.588 373 3938 exclusion phecode
323 Encephalitis Neurological 0.972 0.863 – 1.09 0.637 287 3026 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 1.1 0.859 – 1.42 0.44 65 640 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.04 0.905 – 1.19 0.58 215 2588 exclusion phecode
327 Sleep disorders Neurological 0.982 0.922 – 1.05 0.576 1036 10451 exclusion phecode
327.3 Sleep apnea Neurological 0.964 0.933 – 0.996 0.0289 3910 40063 exclusion phecode
327.4 Insomnia Neurological 1.04 0.881 – 1.22 0.667 142 1449 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.07 0.896 – 1.28 0.448 116 1206 exclusion phecode
331 Other cerebral degenerations Neurological 0.988 0.925 – 1.06 0.729 938 10094 exclusion phecode
331.1 Hydrocephalus Neurological 1.01 0.908 – 1.11 0.909 402 4394 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.01 0.91 – 1.13 0.797 350 3854 exclusion phecode
332 Parkinson's disease Neurological 0.971 0.909 – 1.04 0.372 991 10038 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.09 1.01 – 1.18 0.0207 752 7810 exclusion phecode
333.1 Essential tremor Neurological 1.06 0.91 – 1.22 0.476 184 1877 exclusion phecode
333.2 Myoclonus Neurological 1.06 0.854 – 1.32 0.583 81 845 exclusion phecode
333.4 Torsion dystonia Neurological 1.01 0.876 – 1.16 0.888 213 2162 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1 0.951 – 1.06 0.958 1558 16173 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.03 0.837 – 1.27 0.763 94 1053 exclusion phecode
334.2 Anterior horn cell disease Neurological 1.01 0.885 – 1.16 0.86 223 2196 exclusion phecode
335 Multiple sclerosis Neurological 0.995 0.934 – 1.06 0.883 1035 11552 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.08 0.942 – 1.24 0.272 223 2370 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.06 0.815 – 1.38 0.662 56 634 exclusion phecode
338 Pain Neurological 0.968 0.893 – 1.05 0.424 659 6766 exclusion phecode
338.1 Acute pain Neurological 0.965 0.862 – 1.08 0.528 338 3495 exclusion phecode
338.2 Chronic pain Neurological 0.982 0.876 – 1.1 0.76 326 3355 exclusion phecode
339 Other headache syndromes Neurological 1.02 0.992 – 1.04 0.174 6706 68201 exclusion phecode
340 Migraine Neurological 1.03 0.984 – 1.07 0.231 2446 24557 exclusion phecode
340.1 Migrain with aura Neurological 0.992 0.855 – 1.15 0.919 188 1829 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.927 0.8 – 1.07 0.307 208 2209 exclusion phecode
342 Hemiplegia Neurological 1.03 0.974 – 1.09 0.287 1230 13270 exclusion phecode
343 Infantile cerebral palsy Neurological 1.02 0.854 – 1.23 0.804 121 1289 exclusion phecode
344 Other paralytic syndromes Neurological 1.02 0.933 – 1.12 0.663 509 5869 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.01 0.974 – 1.04 0.749 4170 44589 exclusion phecode
345.1 Epilepsy Neurological 1.02 0.94 – 1.1 0.695 712 7680 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.1 0.992 – 1.23 0.0693 357 3892 exclusion phecode
345.12 Partial epilepsy Neurological 1.03 0.894 – 1.18 0.696 220 2441 exclusion phecode
345.3 Convulsions Neurological 0.994 0.948 – 1.04 0.809 1861 19916 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.03 0.859 – 1.24 0.736 119 1263 exclusion phecode
348 Other conditions of brain Neurological 1.01 0.933 – 1.1 0.794 641 6919 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 0.923 0.807 – 1.06 0.248 230 2334 exclusion phecode
348.4 Cerebral cysts Neurological 1.16 0.96 – 1.4 0.126 111 1180 exclusion phecode
348.7 Coma Neurological 0.981 0.872 – 1.1 0.756 305 3237 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.01 0.876 – 1.17 0.876 198 2241 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.05 0.94 – 1.18 0.382 327 3462 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.969 0.859 – 1.09 0.605 293 3009 exclusion phecode
350 Abnormal movement Neurological 1.03 0.987 – 1.08 0.17 2243 23671 exclusion phecode
350.1 Abnormal involuntary movements Neurological 0.944 0.876 – 1.02 0.128 749 7788 exclusion phecode
350.2 Abnormality of gait Neurological 1.06 1 – 1.12 0.0418 1332 14156 exclusion phecode
350.3 Lack of coordination Neurological 1.14 1.01 – 1.28 0.034 299 3251 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.06 0.79 – 1.43 0.683 47 480 exclusion phecode
351 Other peripheral nerve disorders Neurological 1.01 0.987 – 1.03 0.47 10583 107573 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.03 0.972 – 1.1 0.301 1171 11985 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.05 0.945 – 1.16 0.377 387 4017 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.05 0.971 – 1.13 0.239 764 7729 exclusion phecode
353 Nerve root and plexus disorders Neurological 1.02 0.952 – 1.09 0.61 955 9935 exclusion phecode
353.1 Nerve plexus lesions Neurological 1.06 0.868 – 1.31 0.547 101 1009 exclusion phecode
353.2 Nerve root lesions Neurological 1.29 0.96 – 1.72 0.0918 50 502 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.983 0.819 – 1.18 0.852 116 1353 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 0.964 0.907 – 1.03 0.245 1141 12201 exclusion phecode
358 Myoneural disorders Neurological 0.881 0.752 – 1.03 0.115 168 1857 exclusion phecode
358.1 Myasthenia gravis Neurological 0.9 0.765 – 1.06 0.204 154 1680 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.985 0.883 – 1.1 0.784 355 4100 exclusion phecode
359.1 Muscular dystrophies Neurological 1.07 0.857 – 1.34 0.539 81 1090 exclusion phecode
359.2 Myopathy Neurological 0.971 0.86 – 1.1 0.636 285 3166 exclusion phecode
360 Disorders of the globe Sense Organs 0.861 0.761 – 0.975 0.0184 287 2945 exclusion phecode
360.2 Progressive myopia Sense Organs 0.863 0.744 – 1 0.0521 210 2193 exclusion phecode
361 Retinal detachments and defects Sense Organs 1 0.965 – 1.04 0.909 2893 28939 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.998 0.941 – 1.06 0.942 1250 12375 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 1.12 0.873 – 1.45 0.363 60 600 exclusion phecode
362 Other retinal disorders Sense Organs 1.04 1 – 1.08 0.0301 3250 33678 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.05 1.01 – 1.11 0.0285 1853 19021 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.06 1.01 – 1.11 0.0252 1850 18994 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.85 0.715 – 1.01 0.0649 135 1426 exclusion phecode
362.31 Separation of retinal layers Sense Organs 0.809 0.656 – 0.998 0.0481 90 878 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.05 0.976 – 1.14 0.183 711 7480 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 1.01 0.853 – 1.19 0.933 154 1627 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.1 0.866 – 1.41 0.425 74 723 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.18 0.968 – 1.44 0.103 99 1028 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.02 0.864 – 1.22 0.779 141 1518 exclusion phecode
363.3 Chorioretinal scars Sense Organs 1.1 0.843 – 1.44 0.477 56 608 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.01 0.927 – 1.1 0.805 550 5634 exclusion phecode
364.1 Corneal opacity Sense Organs 0.959 0.774 – 1.19 0.698 82 826 exclusion phecode
364.2 Corneal edema Sense Organs 0.81 0.629 – 1.04 0.103 69 702 exclusion phecode
364.4 Corneal degenerations Sense Organs 1.01 0.868 – 1.18 0.869 173 1768 exclusion phecode
364.41 Keratoconus Sense Organs 1.02 0.803 – 1.29 0.889 75 765 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.891 0.764 – 1.04 0.139 177 1819 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 1.07 0.854 – 1.34 0.561 82 874 exclusion phecode
365 Glaucoma Sense Organs 1.01 0.981 – 1.05 0.403 3772 38791 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 1.08 1 – 1.15 0.0356 893 9143 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 1.08 1.01 – 1.16 0.0272 888 9087 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.984 0.904 – 1.07 0.716 587 6118 exclusion phecode
366 Cataract Sense Organs 1.02 1 – 1.04 0.0122 17088 148148 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 1.4 1.06 – 1.83 0.016 55 615 exclusion phecode
366.2 Senile cataract Sense Organs 1.02 0.997 – 1.05 0.0805 7029 71519 exclusion phecode
366.3 Traumatic cataract Sense Organs 0.86 0.693 – 1.07 0.173 93 940 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.03 0.983 – 1.08 0.217 2055 21183 exclusion phecode
367.1 Myopia Sense Organs 1.05 0.983 – 1.11 0.155 1089 11001 exclusion phecode
367.2 Astigmatism Sense Organs 0.972 0.829 – 1.14 0.728 164 1645 exclusion phecode
367.8 Hypermetropia Sense Organs 0.947 0.822 – 1.09 0.453 210 2211 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.03 0.948 – 1.12 0.486 602 6385 exclusion phecode
368 Visual disturbances Sense Organs 1.08 1.04 – 1.13 0.000141 2532 26060 exclusion phecode
368.1 Amblyopia Sense Organs 1.05 0.956 – 1.16 0.3 451 4670 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.09 1.01 – 1.19 0.0372 612 6471 exclusion phecode
368.3 Anisometropia Sense Organs 0.902 0.755 – 1.08 0.257 139 1382 exclusion phecode
368.4 Visual field defects Sense Organs 0.983 0.871 – 1.11 0.783 286 2980 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 1.08 0.991 – 1.19 0.0767 514 5358 exclusion phecode
369 Infection of the eye Sense Organs 1 0.91 – 1.1 0.982 473 4883 exclusion phecode
369.2 Eye infection, viral Sense Organs 1.11 0.917 – 1.34 0.286 110 1130 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.995 0.853 – 1.16 0.953 175 1871 exclusion phecode
370 Keratitis Sense Organs 1.07 0.939 – 1.23 0.303 238 2492 exclusion phecode
370.1 Corneal ulcer Sense Organs 1.23 1.02 – 1.49 0.03 119 1243 exclusion phecode
371 Inflammation of the eye Sense Organs 0.995 0.956 – 1.04 0.8 2669 26805 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1 0.905 – 1.11 0.998 422 4237 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.99 0.946 – 1.04 0.67 2070 20757 exclusion phecode
372 Disorders of conjunctiva Sense Organs 0.992 0.916 – 1.07 0.848 659 6679 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.996 0.967 – 1.03 0.786 4921 49751 exclusion phecode
374.1 Ectropion or entropion Sense Organs 1.02 0.951 – 1.09 0.64 930 9466 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 1.03 0.981 – 1.09 0.218 1583 15862 exclusion phecode
375 Disorders of lacrimal system Sense Organs 1.01 0.966 – 1.06 0.586 1889 19015 exclusion phecode
375.2 Epiphora Sense Organs 1.01 0.936 – 1.08 0.859 782 7702 exclusion phecode
376 Disorders of the orbit Sense Organs 0.83 0.655 – 1.05 0.125 72 755 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.04 0.928 – 1.17 0.491 305 3155 exclusion phecode
377.1 Optic atrophy Sense Organs 1.23 0.914 – 1.64 0.175 47 513 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.04 0.856 – 1.26 0.707 106 1094 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.05 0.993 – 1.12 0.0854 1206 12481 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.05 0.975 – 1.13 0.197 779 7967 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.02 0.873 – 1.18 0.839 181 1942 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.08 0.945 – 1.23 0.257 234 2439 exclusion phecode
379 Other disorders of eye Sense Organs 0.98 0.945 – 1.02 0.285 3183 32429 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.956 0.901 – 1.01 0.14 1176 12026 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.993 0.943 – 1.05 0.806 1559 15821 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.08 0.851 – 1.38 0.517 64 623 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.999 0.893 – 1.12 0.987 338 3548 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.15 0.973 – 1.37 0.1 142 1488 exclusion phecode
380 Disorders of external ear Sense Organs 0.935 0.857 – 1.02 0.131 573 5673 exclusion phecode
380.1 Otitis externa Sense Organs 0.955 0.863 – 1.06 0.374 431 4511 exclusion phecode
380.4 Impacted cerumen Sense Organs 0.941 0.836 – 1.06 0.317 315 3150 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.969 0.924 – 1.02 0.2 1868 18967 exclusion phecode
381.1 Otitis media Sense Organs 0.976 0.927 – 1.03 0.367 1541 15597 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.999 0.926 – 1.08 0.969 742 7562 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.933 0.799 – 1.09 0.382 173 1672 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.915 0.771 – 1.09 0.308 143 1514 exclusion phecode
381.9 Otorrhea Sense Organs 0.963 0.844 – 1.1 0.578 238 2485 exclusion phecode
382 Otalgia Sense Organs 1.04 0.917 – 1.17 0.565 277 2689 exclusion phecode
383 Otosclerosis Sense Organs 1.07 0.947 – 1.22 0.269 274 2694 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 0.991 0.933 – 1.05 0.777 1153 11415 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 0.998 0.933 – 1.07 0.958 923 9151 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.966 0.893 – 1.04 0.386 699 6956 exclusion phecode
385.3 Cholesteatoma Sense Organs 0.96 0.879 – 1.05 0.37 538 5413 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.951 0.825 – 1.1 0.484 221 2078 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.987 0.936 – 1.04 0.636 1498 15257 exclusion phecode
386.1 Meniere's disease Sense Organs 0.963 0.879 – 1.06 0.417 505 5059 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 1.04 0.923 – 1.17 0.533 321 3294 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.01 0.93 – 1.09 0.843 663 6716 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.02 0.983 – 1.05 0.354 3917 40313 exclusion phecode
388 Other disorders of ear Sense Organs 1.09 0.937 – 1.27 0.257 175 1771 exclusion phecode
389 Hearing loss Sense Organs 1.02 0.984 – 1.05 0.311 3633 36997 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 1.1 0.997 – 1.22 0.0581 396 3972 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.02 0.916 – 1.13 0.764 390 3933 exclusion phecode
389.4 Tinnitus Sense Organs 1.07 0.971 – 1.18 0.171 447 4541 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.04 1.01 – 1.07 0.0146 4189 43700 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.03 0.987 – 1.07 0.189 2563 26621 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.09 1.02 – 1.16 0.00612 1092 11512 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.07 1 – 1.15 0.0472 890 9395 exclusion phecode
395 Heart valve disorders Circulatory System 1.03 0.995 – 1.07 0.0896 3611 37653 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.03 0.989 – 1.07 0.15 2478 25750 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.09 0.958 – 1.25 0.187 236 2487 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.04 0.84 – 1.29 0.718 92 935 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.87 0.704 – 1.08 0.2 86 867 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.07 1.01 – 1.14 0.0199 1263 13409 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.06 0.991 – 1.14 0.0871 860 9001 exclusion phecode
401 Hypertension Circulatory System 1.01 1 – 1.02 0.0492 63789 236404 exclusion phecode
401.1 Essential hypertension Circulatory System 1.01 1 – 1.02 0.0564 63652 236218 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 0.991 0.932 – 1.05 0.778 1064 17193 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.01 0.896 – 1.14 0.882 304 3351 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.981 0.912 – 1.06 0.615 762 13962 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.11 0.872 – 1.42 0.392 66 1297 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.02 0.96 – 1.08 0.567 1288 13235 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.01 0.995 – 1.02 0.244 27378 187719 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.02 0.99 – 1.05 0.181 4500 46324 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.02 1 – 1.04 0.0402 10481 102509 exclusion phecode
411.3 Angina pectoris Circulatory System 1.02 1 – 1.04 0.0306 13846 128599 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.01 0.995 – 1.03 0.197 17835 139619 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.02 0.936 – 1.1 0.699 628 6282 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.02 0.999 – 1.04 0.071 13213 118710 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.947 0.889 – 1.01 0.0882 1068 11061 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.07 1.01 – 1.13 0.0122 1562 16642 exclusion phecode
414.2 ASCVD Circulatory System 1.09 0.829 – 1.43 0.544 58 649 exclusion phecode
415 Pulmonary heart disease Circulatory System 0.985 0.953 – 1.02 0.386 3842 39713 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.87 0.677 – 1.12 0.277 62 650 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.01 0.924 – 1.11 0.784 486 5322 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 0.994 0.893 – 1.11 0.907 363 3959 exclusion phecode
416 Cardiomegaly Circulatory System 1.03 0.99 – 1.08 0.129 2267 24073 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.01 0.993 – 1.02 0.4 24898 238459 exclusion phecode
418.1 Precordial pain Circulatory System 1.01 0.973 – 1.05 0.625 3073 31384 exclusion phecode
420 Carditis Circulatory System 1.01 0.963 – 1.06 0.66 1825 18793 exclusion phecode
420.1 Myocarditis Circulatory System 1.03 0.857 – 1.25 0.727 110 1135 exclusion phecode
420.2 Pericarditis Circulatory System 1.02 0.959 – 1.08 0.538 1167 11976 exclusion phecode
420.21 Acute pericarditis Circulatory System 0.968 0.837 – 1.12 0.662 204 2006 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.17 0.956 – 1.42 0.128 102 1000 exclusion phecode
420.3 Endocarditis Circulatory System 0.987 0.907 – 1.07 0.752 612 6385 exclusion phecode
425 Cardiomyopathy Circulatory System 1.08 1.01 – 1.15 0.0217 1062 11415 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.06 0.999 – 1.14 0.0543 1036 11097 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.04 0.862 – 1.27 0.655 113 1217 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.01 0.853 – 1.2 0.894 143 1473 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.32 0.991 – 1.76 0.0576 52 557 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.01 0.987 – 1.04 0.31 5929 62038 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.01 0.964 – 1.06 0.636 1812 19091 exclusion phecode
426.21 First degree AV block Circulatory System 1.03 0.956 – 1.1 0.472 841 8928 exclusion phecode
426.23 Second degree AV block Circulatory System 1.06 0.955 – 1.18 0.278 391 4055 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 0.953 0.869 – 1.04 0.299 502 5261 exclusion phecode
426.25 Other heart block Circulatory System 0.986 0.82 – 1.18 0.878 116 1179 exclusion phecode
426.3 Bundle branch block Circulatory System 1.02 0.981 – 1.06 0.331 2832 29861 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.01 0.958 – 1.07 0.638 1286 13410 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.04 0.982 – 1.09 0.202 1460 15576 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.988 0.858 – 1.14 0.863 210 2065 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1 0.753 – 1.34 0.975 53 527 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.04 0.994 – 1.09 0.0893 2099 22312 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.04 0.989 – 1.09 0.131 1927 20475 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.02 1 – 1.03 0.00838 20987 182754 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1 0.966 – 1.05 0.805 2733 28447 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1 0.959 – 1.05 0.873 2010 20737 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.02 0.943 – 1.09 0.687 782 8487 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.03 1.01 – 1.04 0.00724 12775 119791 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.997 0.959 – 1.04 0.867 2844 28847 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.04 0.973 – 1.11 0.258 995 10777 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.1 0.979 – 1.24 0.11 302 3146 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.02 0.95 – 1.1 0.581 818 8946 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.02 0.95 – 1.09 0.601 835 8463 exclusion phecode
427.6 Premature beats Circulatory System 1.03 0.939 – 1.13 0.514 469 4786 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1.08 0.878 – 1.32 0.471 99 1049 exclusion phecode
427.7 Tachycardia NOS Circulatory System 0.997 0.95 – 1.05 0.894 1810 19335 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.991 0.888 – 1.1 0.865 357 3579 exclusion phecode
427.9 Palpitations Circulatory System 1.04 1 – 1.07 0.0453 3272 33286 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.04 1.01 – 1.07 0.0076 4644 50470 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.04 0.987 – 1.09 0.145 1677 19016 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.04 1.01 – 1.08 0.0148 3707 40071 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.01 0.932 – 1.1 0.781 628 6356 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.33 0.978 – 1.82 0.0688 39 579 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.03 0.939 – 1.14 0.499 456 4637 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.01 0.864 – 1.18 0.897 174 1730 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.04 0.989 – 1.1 0.124 1610 16638 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.04 0.96 – 1.12 0.355 707 7216 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.02 0.943 – 1.11 0.604 656 6822 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.04 0.906 – 1.18 0.61 226 2379 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.01 0.983 – 1.03 0.578 7465 77829 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.05 0.988 – 1.13 0.113 1000 10559 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.1 0.945 – 1.29 0.215 185 2022 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.02 0.985 – 1.05 0.285 3633 37777 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.02 0.962 – 1.07 0.583 1437 14989 exclusion phecode
433.3 Cerebral ischemia Circulatory System 0.991 0.951 – 1.03 0.686 2483 25761 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 0.993 0.946 – 1.04 0.758 1844 18989 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.01 0.905 – 1.13 0.821 322 3384 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.02 0.961 – 1.09 0.467 1047 11332 exclusion phecode
440 Atherosclerosis Circulatory System 1.03 0.968 – 1.1 0.347 1113 12510 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.26 0.976 – 1.64 0.0754 60 1004 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.06 0.974 – 1.14 0.185 662 7365 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 0.943 0.823 – 1.08 0.394 233 2568 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 0.984 0.898 – 1.08 0.722 509 5365 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.99 0.869 – 1.13 0.88 241 2476 exclusion phecode
442 Other aneurysm Circulatory System 1.04 0.988 – 1.09 0.14 1628 17132 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.04 0.979 – 1.1 0.217 1256 13299 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1 0.929 – 1.08 0.999 784 8506 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.08 0.863 – 1.35 0.497 82 913 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.18 0.995 – 1.4 0.0569 145 1529 exclusion phecode
442.4 Arterial dissection Circulatory System 1.12 0.846 – 1.5 0.419 49 485 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 0.927 0.794 – 1.08 0.337 172 1770 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.01 0.971 – 1.04 0.726 3202 35052 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.02 0.951 – 1.09 0.639 932 9885 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.07 0.942 – 1.21 0.31 270 3525 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1 0.967 – 1.04 0.855 3032 32893 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1 0.957 – 1.05 0.964 2126 23343 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 0.97 0.9 – 1.05 0.424 764 8359 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.04 0.948 – 1.15 0.38 459 5070 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.03 0.954 – 1.12 0.422 677 7217 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 1.02 0.865 – 1.21 0.802 149 1669 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.05 0.937 – 1.17 0.404 324 3346 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.1 0.946 – 1.27 0.225 198 2139 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 0.969 0.911 – 1.03 0.327 1084 11968 exclusion phecode
447.1 Stricture of artery Circulatory System 0.988 0.916 – 1.07 0.761 723 7900 exclusion phecode
448 Disease of capillaries Circulatory System 0.878 0.73 – 1.06 0.167 120 1255 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.02 0.936 – 1.11 0.649 564 6146 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.01 0.971 – 1.04 0.741 3419 35273 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.01 0.97 – 1.04 0.734 3184 32896 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1.03 0.937 – 1.13 0.537 470 5038 exclusion phecode
454 Varicose veins Circulatory System 1.02 0.994 – 1.04 0.152 9660 97444 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1.01 0.993 – 1.04 0.189 9932 99886 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1 0.918 – 1.09 0.968 525 5594 exclusion phecode
455 Hemorrhoids Circulatory System 1 0.989 – 1.02 0.661 20567 207066 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.965 0.819 – 1.14 0.667 153 1651 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.04 0.829 – 1.3 0.744 84 861 exclusion phecode
458 Hypotension Circulatory System 1 0.971 – 1.03 0.978 4821 51073 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 0.994 0.935 – 1.06 0.835 1138 11918 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.12 0.967 – 1.29 0.132 197 2079 exclusion phecode
458.9 Hypotension NOS Circulatory System 0.99 0.953 – 1.03 0.615 2902 30887 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.01 0.992 – 1.03 0.296 13833 142591 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.12 0.93 – 1.36 0.227 120 1258 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.01 0.994 – 1.03 0.196 13700 141369 exclusion phecode
464 Acute sinusitis Respiratory 1.08 0.922 – 1.28 0.325 164 1714 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.02 0.976 – 1.07 0.336 1954 19959 exclusion phecode
465.2 Acute pharyngitis Respiratory 1.01 0.934 – 1.09 0.838 714 7309 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.953 0.802 – 1.13 0.583 150 1445 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.994 0.962 – 1.03 0.692 4190 41856 exclusion phecode
471 Nasal polyps Respiratory 1.03 0.988 – 1.07 0.182 2964 29684 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.987 0.92 – 1.06 0.726 843 8502 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 0.989 0.947 – 1.03 0.616 2232 22502 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.06 0.852 – 1.31 0.62 93 907 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.937 0.817 – 1.08 0.356 225 2348 exclusion phecode
473.4 Voice disturbance Respiratory 0.971 0.908 – 1.04 0.387 940 9468 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 0.953 0.905 – 1 0.0675 1574 15672 exclusion phecode
474.1 Acute tonsillitis Respiratory 0.941 0.856 – 1.03 0.202 472 4807 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.973 0.912 – 1.04 0.403 1013 9836 exclusion phecode
475 Chronic sinusitis Respiratory 0.985 0.944 – 1.03 0.487 2257 22885 exclusion phecode
476 Allergic rhinitis Respiratory 0.976 0.911 – 1.04 0.478 921 9306 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.02 0.976 – 1.07 0.375 2109 21774 exclusion phecode
478 Throat pain Respiratory 0.989 0.883 – 1.11 0.85 330 3302 exclusion phecode
479 Other upper respiratory disease Respiratory 0.995 0.961 – 1.03 0.76 3591 36249 exclusion phecode
480 Pneumonia Respiratory 1.01 0.99 – 1.03 0.306 8662 91949 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.02 0.994 – 1.05 0.132 5572 58972 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.02 0.991 – 1.05 0.183 4939 52253 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.43 1.12 – 1.82 0.00461 73 816 exclusion phecode
480.2 Viral pneumonia Respiratory 1.28 0.982 – 1.67 0.0679 58 648 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.973 0.778 – 1.22 0.813 83 890 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.958 0.885 – 1.04 0.287 658 7092 exclusion phecode
481 Influenza Respiratory 1.12 0.988 – 1.26 0.0778 277 2914 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.859 0.729 – 1.01 0.0686 161 1706 exclusion phecode
495 Asthma Respiratory 1 0.989 – 1.02 0.693 22131 219282 exclusion phecode
495.2 Asthma with exacerbation Respiratory 0.997 0.866 – 1.15 0.97 211 2175 exclusion phecode
496 Chronic airway obstruction Respiratory 0.994 0.973 – 1.02 0.605 8804 89879 exclusion phecode
496.1 Emphysema Respiratory 0.968 0.917 – 1.02 0.226 1464 15553 exclusion phecode
496.2 Chronic bronchitis Respiratory 0.998 0.957 – 1.04 0.915 2469 26161 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.01 0.968 – 1.06 0.625 2260 24029 exclusion phecode
496.3 Bronchiectasis Respiratory 1.03 0.974 – 1.08 0.335 1584 16541 exclusion phecode
497 Bronchitis Respiratory 0.965 0.883 – 1.05 0.426 540 5480 exclusion phecode
500 Lung disease due to external agents Respiratory 1.01 0.907 – 1.12 0.868 360 3700 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.03 0.812 – 1.32 0.785 69 681 exclusion phecode
500.2 Pneumoconiosis Respiratory 1.01 0.877 – 1.16 0.921 215 2210 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.03 0.947 – 1.13 0.456 554 5878 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.01 0.938 – 1.09 0.81 777 8101 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.07 0.965 – 1.19 0.195 385 4483 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.945 0.837 – 1.07 0.368 276 2857 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 0.741 0.563 – 0.976 0.0328 49 535 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.02 0.956 – 1.09 0.542 956 10228 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 0.996 0.969 – 1.02 0.778 5402 57184 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.986 0.938 – 1.04 0.574 1707 17627 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1 0.961 – 1.05 0.835 2094 23208 exclusion phecode
509.1 Respiratory failure Respiratory 1 0.953 – 1.05 0.947 1670 18442 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.01 0.959 – 1.07 0.675 1457 16078 exclusion phecode
509.5 Respiratory arrest Respiratory 1.02 0.844 – 1.24 0.811 109 1277 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.947 0.844 – 1.06 0.359 316 3466 exclusion phecode
510 Other diseases of lung Respiratory 1.01 0.933 – 1.1 0.776 645 6627 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.01 0.983 – 1.03 0.61 7697 79396 exclusion phecode
512.1 Wheezing Respiratory 0.99 0.853 – 1.15 0.894 189 1898 exclusion phecode
512.2 Painful respiration Respiratory 1.03 0.883 – 1.2 0.721 181 1792 exclusion phecode
512.7 Shortness of breath Respiratory 0.998 0.969 – 1.03 0.9 4936 51469 exclusion phecode
512.8 Cough Respiratory 1.03 0.986 – 1.07 0.193 2450 25228 exclusion phecode
512.9 Other dyspnea Respiratory 1.02 0.943 – 1.09 0.681 780 8047 exclusion phecode
513 Respiratory abnormalities Respiratory 0.964 0.882 – 1.06 0.43 528 5387 exclusion phecode
513.3 Hypoventilation Respiratory 0.947 0.736 – 1.22 0.671 67 725 exclusion phecode
513.4 Hyperventilation Respiratory 0.986 0.863 – 1.13 0.837 243 2404 exclusion phecode
513.8 Disorders of diaphragm Respiratory 0.951 0.793 – 1.14 0.59 131 1401 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.02 0.971 – 1.06 0.499 2099 21850 exclusion phecode
516 Abnormal sputum Respiratory 1.02 0.974 – 1.07 0.375 1822 18967 exclusion phecode
516.1 Hemoptysis Respiratory 1.03 0.976 – 1.08 0.32 1770 18454 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.01 0.987 – 1.03 0.38 7892 82669 exclusion phecode
519.2 Respiratory complications Respiratory 1.07 0.945 – 1.21 0.29 268 2917 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.01 0.984 – 1.03 0.532 7456 78145 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.11 0.976 – 1.25 0.112 262 2667 exclusion phecode
520 Disorders of tooth development Digestive 0.979 0.933 – 1.03 0.403 1794 17930 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.946 0.7 – 1.28 0.715 44 462 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.982 0.938 – 1.03 0.419 2076 20655 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 0.984 0.945 – 1.02 0.436 2627 26775 exclusion phecode
521.1 Dental caries Digestive 0.985 0.946 – 1.03 0.459 2634 26897 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.04 0.99 – 1.1 0.116 1523 15568 exclusion phecode
522.5 Periapical abscess Digestive 1.08 1.01 – 1.15 0.023 1007 10279 exclusion phecode
523 Gingival and periodontal diseases Digestive 0.993 0.941 – 1.05 0.805 1460 14677 exclusion phecode
523.1 Gingivitis Digestive 0.952 0.765 – 1.18 0.658 95 977 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1 0.938 – 1.07 0.982 1014 10230 exclusion phecode
523.31 Acute periodontitis Digestive 1.04 0.955 – 1.13 0.383 588 5815 exclusion phecode
523.32 Chronic periodontitis Digestive 0.929 0.845 – 1.02 0.133 477 4887 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.978 0.864 – 1.11 0.729 283 2908 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.986 0.867 – 1.12 0.828 261 2675 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1 0.961 – 1.05 0.883 2308 23392 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.02 0.794 – 1.32 0.861 61 624 exclusion phecode
526 Diseases of the jaws Digestive 0.984 0.915 – 1.06 0.673 792 8111 exclusion phecode
526.1 Cysts of the jaws Digestive 1.06 0.936 – 1.19 0.379 286 2921 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.813 0.616 – 1.07 0.143 54 529 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 0.995 0.863 – 1.15 0.946 204 2065 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.986 0.855 – 1.14 0.851 198 1988 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.878 0.71 – 1.09 0.231 92 976 exclusion phecode
526.9 Jaw disease NOS Digestive 0.98 0.842 – 1.14 0.789 195 2049 exclusion phecode
527 Diseases of the salivary glands Digestive 1.02 0.935 – 1.1 0.706 602 6072 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.19 0.936 – 1.52 0.156 75 733 exclusion phecode
527.2 Sialoadenitis Digestive 0.998 0.891 – 1.12 0.973 320 3194 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.01 0.757 – 1.35 0.934 48 542 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.15 0.951 – 1.4 0.148 106 1047 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.996 0.961 – 1.03 0.826 3367 33938 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.08 0.977 – 1.2 0.131 406 4086 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.05 0.934 – 1.17 0.444 332 3411 exclusion phecode
528.12 Oral aphthae Digestive 1.3 1.03 – 1.64 0.0277 79 746 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.99 0.841 – 1.17 0.907 155 1565 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.797 0.652 – 0.974 0.0265 105 1059 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.892 0.717 – 1.11 0.307 84 803 exclusion phecode
528.5 Diseases of lips Digestive 1.04 0.952 – 1.13 0.415 598 5951 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.09 0.961 – 1.23 0.183 269 2706 exclusion phecode
528.7 Sialolithiasis Digestive 1.06 0.937 – 1.2 0.343 272 2785 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 0.962 0.903 – 1.02 0.229 1060 10804 exclusion phecode
529.1 Glossitis Digestive 0.969 0.851 – 1.1 0.629 253 2620 exclusion phecode
530 Diseases of esophagus Digestive 0.999 0.987 – 1.01 0.866 29139 246234 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1 0.988 – 1.01 0.96 27276 240204 exclusion phecode
530.11 GERD Digestive 0.998 0.983 – 1.01 0.745 19704 198511 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.02 0.993 – 1.06 0.129 4610 46466 exclusion phecode
530.14 Reflux esophagitis Digestive 0.991 0.97 – 1.01 0.407 9192 92494 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.984 0.932 – 1.04 0.56 1417 14866 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 0.961 0.914 – 1.01 0.126 1669 16688 exclusion phecode
530.5 Disorders of esophageal motility Digestive 0.966 0.884 – 1.05 0.433 553 5589 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.02 0.854 – 1.21 0.836 132 1361 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.02 0.901 – 1.15 0.766 280 3072 exclusion phecode
530.9 Heartburn Digestive 0.993 0.945 – 1.04 0.763 1791 18069 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.01 0.987 – 1.04 0.311 6079 63005 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.994 0.909 – 1.09 0.898 537 5713 exclusion phecode
531.2 Gastric ulcer Digestive 1.01 0.974 – 1.04 0.65 3458 36097 exclusion phecode
531.3 Duodenal ulcer Digestive 1.02 0.982 – 1.06 0.288 2605 26807 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.05 0.947 – 1.17 0.34 374 3800 exclusion phecode
532 Dysphagia Digestive 1.02 0.989 – 1.05 0.232 5541 56359 exclusion phecode
535 Gastritis and duodenitis Digestive 0.996 0.983 – 1.01 0.567 24329 230109 exclusion phecode
535.1 Acute gastritis Digestive 0.987 0.926 – 1.05 0.685 1017 10435 exclusion phecode
535.2 Atrophic gastritis Digestive 0.992 0.886 – 1.11 0.893 326 3280 exclusion phecode
535.6 Duodenitis Digestive 1 0.977 – 1.03 0.859 6666 67630 exclusion phecode
535.8 Other specified gastritis Digestive 1 0.978 – 1.03 0.835 6950 70704 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.96 0.788 – 1.17 0.682 106 1047 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.04 0.908 – 1.19 0.565 229 2250 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 0.961 0.925 – 0.998 0.0412 2888 29917 exclusion phecode
540 Appendiceal conditions Digestive 0.998 0.96 – 1.04 0.938 2736 27348 exclusion phecode
540.1 Appendicitis Digestive 1 0.965 – 1.05 0.824 2571 25638 exclusion phecode
540.11 Acute appendicitis Digestive 1.01 0.97 – 1.06 0.576 2313 23043 exclusion phecode
550 Abdominal hernia Digestive 1.01 0.998 – 1.02 0.129 40193 249397 exclusion phecode
550.1 Inguinal hernia Digestive 1.02 1.01 – 1.04 0.00628 14537 113884 exclusion phecode
550.2 Diaphragmatic hernia Digestive 0.998 0.985 – 1.01 0.814 23086 209711 exclusion phecode
550.3 Femoral hernia Digestive 1 0.914 – 1.09 0.994 518 5624 exclusion phecode
550.4 Umbilical hernia Digestive 1.01 0.973 – 1.05 0.652 3290 33596 exclusion phecode
550.5 Ventral hernia Digestive 1 0.965 – 1.04 0.919 2922 30304 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.03 0.997 – 1.07 0.0725 3873 39244 exclusion phecode
555.1 Regional enteritis Digestive 1.02 0.965 – 1.07 0.508 1508 15275 exclusion phecode
555.2 Ulcerative colitis Digestive 1.02 0.982 – 1.06 0.287 2772 28168 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.04 0.942 – 1.14 0.468 478 4760 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.07 1 – 1.15 0.0482 909 9328 exclusion phecode
556.1 Ulceration of intestine Digestive 1.09 0.998 – 1.19 0.0561 569 5884 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.04 0.911 – 1.18 0.578 250 2612 exclusion phecode
557.1 Celiac disease Digestive 0.994 0.943 – 1.05 0.826 1521 16070 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.01 0.991 – 1.03 0.313 13168 135805 exclusion phecode
559 Ileostomy status Digestive 1.01 0.955 – 1.07 0.751 1419 14720 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 0.986 0.951 – 1.02 0.445 3323 34463 exclusion phecode
560.1 Paralytic ileus Digestive 0.964 0.875 – 1.06 0.462 450 4660 exclusion phecode
560.2 Impaction of intestine Digestive 1.01 0.876 – 1.16 0.912 213 2320 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.01 0.932 – 1.09 0.844 694 7243 exclusion phecode
560.4 Other intestinal obstruction Digestive 0.991 0.953 – 1.03 0.648 2834 29336 exclusion phecode
561 Symptoms involving digestive system Digestive 1.01 0.997 – 1.03 0.115 13504 137400 exclusion phecode
561.1 Diarrhea Digestive 1.02 0.922 – 1.13 0.684 385 4027 exclusion phecode
561.2 Flatulence Digestive 1.02 0.967 – 1.08 0.459 1425 14754 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1.01 0.999 – 1.03 0.0634 23236 186976 exclusion phecode
562.1 Diverticulosis Digestive 1.01 0.999 – 1.03 0.0646 23202 186930 exclusion phecode
563 Constipation Digestive 1.01 0.992 – 1.04 0.216 8725 90241 exclusion phecode
564 Functional digestive disorders Digestive 1.02 1 – 1.03 0.0512 18662 184843 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.02 0.987 – 1.05 0.267 4672 47494 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1 0.951 – 1.06 0.863 1386 14384 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.02 1 – 1.04 0.0562 13175 134330 exclusion phecode
565 Anal and rectal conditions Digestive 1.01 0.989 – 1.03 0.415 12955 130888 exclusion phecode
565.1 Anal and rectal polyp Digestive 1.01 0.981 – 1.03 0.629 6485 65427 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.04 0.965 – 1.12 0.306 737 8206 exclusion phecode
568 Other disorders of peritoneum Digestive 1.01 0.972 – 1.05 0.594 2753 28314 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.01 0.973 – 1.05 0.537 2615 26887 exclusion phecode
569 Other disorders of intestine Digestive 1 0.967 – 1.04 0.942 3570 36839 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.05 0.878 – 1.27 0.572 126 1263 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.12 1.01 – 1.24 0.0335 405 4285 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 0.976 0.936 – 1.02 0.243 2405 26336 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 0.993 0.94 – 1.05 0.793 1404 14953 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.911 0.743 – 1.12 0.373 94 1027 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 0.827 0.719 – 0.952 0.0083 215 2190 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.949 0.882 – 1.02 0.163 764 8821 exclusion phecode
571.81 Portal hypertension Digestive 0.949 0.859 – 1.05 0.308 408 4760 exclusion phecode
572 Ascites (non malignant) Digestive 0.971 0.916 – 1.03 0.318 1244 13611 exclusion phecode
573 Other disorders of liver Digestive 1.05 0.991 – 1.11 0.101 1243 13216 exclusion phecode
573.2 Liver replaced by transplant Digestive 0.994 0.776 – 1.27 0.959 69 875 exclusion phecode
573.3 Hepatomegaly Digestive 1.03 0.898 – 1.17 0.707 240 2643 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 0.933 0.865 – 1.01 0.0685 770 8007 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 0.96 0.924 – 0.997 0.0345 2945 30586 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 0.935 0.804 – 1.09 0.389 182 1873 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 0.995 0.977 – 1.01 0.548 13358 134633 exclusion phecode
574.1 Cholelithiasis Digestive 0.991 0.972 – 1.01 0.356 11585 116721 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.992 0.935 – 1.05 0.779 1279 13080 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.984 0.955 – 1.01 0.301 4665 46734 exclusion phecode
574.2 Calculus of bile duct Digestive 1.01 0.966 – 1.05 0.703 2246 22730 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.03 0.988 – 1.07 0.166 2341 23953 exclusion phecode
575 Other biliary tract disease Digestive 1.01 0.976 – 1.05 0.544 3284 33572 exclusion phecode
575.1 Cholangitis Digestive 0.989 0.894 – 1.09 0.829 419 4416 exclusion phecode
575.2 Obstruction of bile duct Digestive 0.976 0.901 – 1.06 0.559 669 6827 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 1.01 0.913 – 1.12 0.828 401 3955 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.04 0.977 – 1.1 0.229 1189 12160 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.01 0.94 – 1.08 0.835 865 8964 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.07 0.946 – 1.21 0.29 291 3019 exclusion phecode
577 Diseases of pancreas Digestive 0.981 0.94 – 1.02 0.384 2287 23522 exclusion phecode
577.1 Acute pancreatitis Digestive 0.954 0.908 – 1 0.0625 1725 17574 exclusion phecode
577.2 Chronic pancreatitis Digestive 0.924 0.837 – 1.02 0.117 424 4647 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.946 0.84 – 1.06 0.354 315 3205 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.993 – 1.02 0.295 17931 182156 exclusion phecode
578.1 Hematemesis Digestive 0.96 0.913 – 1.01 0.114 1667 17532 exclusion phecode
578.2 Blood in stool Digestive 0.973 0.931 – 1.02 0.214 2258 23380 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.02 0.997 – 1.04 0.0914 11364 115051 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.02 0.994 – 1.06 0.12 4583 46649 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.952 0.899 – 1.01 0.0875 1301 13492 exclusion phecode
579.2 Splenomegaly Digestive 0.961 0.862 – 1.07 0.471 354 3832 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.1 1.05 – 1.17 0.000352 1411 14399 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.93 0.87 – 0.994 0.0316 934 13659 exclusion phecode
580.1 Glomerulonephritis Genitourinary 0.885 0.816 – 0.96 0.00324 638 9308 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.985 0.716 – 1.36 0.928 40 672 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.963 0.772 – 1.2 0.739 82 1193 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.872 0.798 – 0.954 0.00261 531 7742 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.06 0.937 – 1.2 0.352 262 4226 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.05 0.883 – 1.25 0.587 139 2212 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.05 0.885 – 1.24 0.587 144 2268 exclusion phecode
585 Renal failure Genitourinary 0.979 0.952 – 1.01 0.147 5181 62619 exclusion phecode
585.1 Acute renal failure Genitourinary 0.998 0.965 – 1.03 0.927 3560 40827 exclusion phecode
585.2 Renal failure NOS Genitourinary 0.935 0.878 – 0.997 0.0405 1000 13191 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.936 0.889 – 0.986 0.0128 1533 23731 exclusion phecode
585.31 Renal dialysis Genitourinary 1.21 1.05 – 1.4 0.0108 183 4427 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.05 1.01 – 1.1 0.00774 2709 30044 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.995 0.836 – 1.18 0.953 136 1838 exclusion phecode
586.11 Small kidney Genitourinary 0.946 0.784 – 1.14 0.562 119 1589 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.05 0.986 – 1.12 0.129 1079 11303 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.18 0.897 – 1.56 0.235 52 727 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.11 1.03 – 1.19 0.0072 750 8190 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.19 0.985 – 1.43 0.0709 117 3306 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.06 0.795 – 1.4 0.708 45 882 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 0.942 0.752 – 1.18 0.605 77 1032 exclusion phecode
590 Pyelonephritis Genitourinary 1.02 0.955 – 1.08 0.589 1058 11470 exclusion phecode
591 Urinary tract infection Genitourinary 1.02 1 – 1.04 0.0246 10338 108406 exclusion phecode
592 Cystitis and urethritis Genitourinary 0.967 0.928 – 1.01 0.106 2531 25781 exclusion phecode
592.1 Cystitis Genitourinary 0.977 0.937 – 1.02 0.26 2470 25206 exclusion phecode
592.11 Acute cystitis Genitourinary 0.831 0.688 – 1 0.0555 112 1227 exclusion phecode
592.12 Chronic cystitis Genitourinary 0.962 0.891 – 1.04 0.317 738 7748 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 0.869 0.756 – 0.999 0.0486 218 2107 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.807 0.677 – 0.962 0.0168 146 1447 exclusion phecode
593 Hematuria Genitourinary 1.01 0.991 – 1.03 0.368 14035 142638 exclusion phecode
594 Urinary calculus Genitourinary 1.08 1.05 – 1.11 7.52e-09 5644 57520 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.13 1.08 – 1.17 2.2e-09 2773 28502 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.03 0.954 – 1.12 0.433 685 7099 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.1 1.05 – 1.15 6.39e-05 2139 21817 exclusion phecode
594.8 Renal colic Genitourinary 1.06 1.01 – 1.11 0.0127 1820 18504 exclusion phecode
595 Hydronephrosis Genitourinary 1.01 0.957 – 1.06 0.789 1614 17343 exclusion phecode
596 Other disorders of bladder Genitourinary 1 0.978 – 1.02 0.961 8502 87422 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.02 0.971 – 1.07 0.448 1790 18185 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 0.969 0.916 – 1.02 0.259 1371 14531 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.02 0.984 – 1.06 0.285 3368 34678 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.03 0.991 – 1.07 0.139 2882 29551 exclusion phecode
597.2 Urinary complications NEC Genitourinary 0.882 0.682 – 1.14 0.337 62 686 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.01 0.972 – 1.05 0.645 3097 31469 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.2 1.05 – 1.37 0.00944 240 2718 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.993 – 1.03 0.26 15768 161194 exclusion phecode
599.1 Urinary obstruction Genitourinary 1.02 0.851 – 1.22 0.846 133 1488 exclusion phecode
599.2 Retention of urine Genitourinary 1.04 1.02 – 1.07 0.00219 5855 60734 exclusion phecode
599.3 Dysuria Genitourinary 0.999 0.938 – 1.06 0.98 1038 10612 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.997 0.973 – 1.02 0.8 7253 74032 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.02 0.99 – 1.06 0.172 3506 35784 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.21 0.971 – 1.52 0.0892 91 950 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1 0.758 – 1.33 0.986 54 541 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1 0.955 – 1.05 0.89 1687 17229 exclusion phecode
600 Hyperplasia of prostate Genitourinary 1.02 1 – 1.04 0.0542 10155 81642 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 1.01 0.965 – 1.06 0.632 1906 19341 exclusion phecode
601.1 Prostatitis Genitourinary 1.02 0.969 – 1.08 0.404 1436 14541 exclusion phecode
601.11 Acute prostatitis Genitourinary 1.09 0.944 – 1.25 0.248 215 2190 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1.02 0.952 – 1.1 0.544 838 8448 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 1 0.773 – 1.3 0.998 58 548 exclusion phecode
601.4 Balanoposthitis Genitourinary 1.06 0.935 – 1.2 0.361 269 2665 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.978 0.864 – 1.11 0.725 269 2799 exclusion phecode
602 Other disorders of prostate Genitourinary 1.06 1 – 1.12 0.0491 1222 12370 exclusion phecode
603 Other disorders of testis Genitourinary 1.02 0.972 – 1.07 0.44 1967 20065 exclusion phecode
603.1 Hydrocele Genitourinary 1 0.943 – 1.06 0.982 1233 12487 exclusion phecode
604 Disorders of penis Genitourinary 1 0.968 – 1.04 0.798 3004 30595 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.99 0.951 – 1.03 0.648 2480 25337 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 1.04 0.922 – 1.18 0.503 260 2622 exclusion phecode
608 Other disorders of male genital organs Genitourinary 1.02 0.984 – 1.07 0.236 2608 26319 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.16 1 – 1.34 0.0474 194 1994 exclusion phecode
609.1 Infertility, male Genitourinary 1.24 0.949 – 1.63 0.114 58 595 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 1.11 0.942 – 1.3 0.219 153 1584 exclusion phecode
610 Benign mammary dysplasias Genitourinary 1.03 0.983 – 1.08 0.23 2075 20697 exclusion phecode
610.1 Cystic mastopathy Genitourinary 1.05 0.972 – 1.13 0.228 780 7714 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1.15 1.01 – 1.31 0.0344 247 2560 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 1.04 0.915 – 1.19 0.522 243 2524 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.999 0.941 – 1.06 0.98 1173 11563 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.06 0.969 – 1.15 0.214 587 5768 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.02 0.966 – 1.08 0.438 1297 13133 exclusion phecode
611.1 Abnormal mammogram Genitourinary 1.04 0.792 – 1.36 0.789 50 474 exclusion phecode
611.3 Lump or mass in breast Genitourinary 1.02 0.963 – 1.08 0.499 1252 12701 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.05 0.976 – 1.13 0.185 760 7576 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.04 0.962 – 1.12 0.344 732 7255 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 1.02 0.788 – 1.32 0.887 60 597 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 1.04 0.983 – 1.1 0.172 1360 13776 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.02 0.935 – 1.11 0.695 596 6014 exclusion phecode
613.5 Mastodynia Genitourinary 0.878 0.678 – 1.14 0.321 61 645 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 1.08 0.988 – 1.18 0.0925 574 5820 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1.06 0.937 – 1.19 0.377 271 2733 exclusion phecode
613.9 Breast disorder NOS Genitourinary 1.04 0.891 – 1.22 0.612 178 1694 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.02 0.995 – 1.06 0.109 4727 47749 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.03 0.987 – 1.08 0.161 2077 21185 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.06 0.981 – 1.15 0.141 686 6913 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.9 0.678 – 1.2 0.468 49 507 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.14 1.02 – 1.28 0.018 351 3519 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.01 0.898 – 1.14 0.837 293 2907 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.955 0.832 – 1.1 0.51 221 2310 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.999 0.956 – 1.04 0.968 2170 21831 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.981 0.921 – 1.04 0.54 1082 11113 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.948 0.854 – 1.05 0.318 371 3603 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.06 0.978 – 1.15 0.155 624 6343 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.998 0.868 – 1.15 0.977 233 2295 exclusion phecode
615 Endometriosis Genitourinary 0.974 0.94 – 1.01 0.147 3332 33659 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.07 0.935 – 1.23 0.323 241 2540 exclusion phecode
618 Genital prolapse Genitourinary 1 0.981 – 1.02 0.886 9590 97663 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.994 0.968 – 1.02 0.642 6081 61745 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.01 0.979 – 1.04 0.546 4382 45038 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.984 0.888 – 1.09 0.758 412 4240 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.01 0.929 – 1.11 0.748 553 5603 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1.01 0.981 – 1.03 0.682 7223 72858 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.985 0.905 – 1.07 0.727 600 6075 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 1 0.966 – 1.04 0.818 2782 27788 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.995 0.954 – 1.04 0.818 2360 23751 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.01 0.955 – 1.07 0.755 1462 14742 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.02 0.961 – 1.09 0.471 1103 11212 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 0.947 0.735 – 1.22 0.674 61 594 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.954 0.892 – 1.02 0.17 943 9469 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.993 0.972 – 1.02 0.555 8729 87428 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.999 0.974 – 1.02 0.925 6556 65656 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 0.978 0.941 – 1.02 0.265 2868 28589 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 0.999 0.939 – 1.06 0.977 1087 10607 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.92 0.849 – 0.998 0.0437 660 6593 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.934 0.805 – 1.08 0.367 198 1961 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 0.898 0.806 – 1 0.0505 361 3657 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.989 0.96 – 1.02 0.445 4862 48871 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.992 0.951 – 1.03 0.692 2388 24005 exclusion phecode
625.1 Dyspareunia Genitourinary 1.01 0.949 – 1.08 0.719 1009 9914 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.997 0.979 – 1.02 0.723 13391 96339 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.993 0.974 – 1.01 0.457 11683 92053 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 1.04 0.848 – 1.29 0.683 92 915 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 0.992 0.97 – 1.02 0.507 8027 76809 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.974 0.926 – 1.03 0.315 1638 16561 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 1.01 0.976 – 1.05 0.494 3151 31883 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.995 0.943 – 1.05 0.846 1474 14952 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 1.06 0.891 – 1.26 0.504 136 1320 exclusion phecode
626.8 Infertility, female Genitourinary 1.04 0.978 – 1.1 0.21 1137 11393 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.987 0.965 – 1.01 0.247 8598 86729 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 0.987 0.964 – 1.01 0.299 7484 75444 exclusion phecode
627.2 Symptomatic menopause Genitourinary 1.1 0.93 – 1.3 0.267 146 1512 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.962 0.899 – 1.03 0.25 928 9259 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 0.981 0.862 – 1.12 0.775 253 2583 exclusion phecode
628 Ovarian cyst Genitourinary 0.999 0.967 – 1.03 0.95 3937 39691 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1 0.973 – 1.04 0.817 4432 30471 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1 0.937 – 1.07 0.994 951 9438 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.998 0.885 – 1.13 0.974 280 2759 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1 0.952 – 1.05 0.979 1667 14557 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.02 0.947 – 1.1 0.603 736 7246 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.977 0.918 – 1.04 0.469 1067 10314 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.01 0.962 – 1.05 0.759 1959 16700 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 1.01 0.925 – 1.1 0.813 525 5136 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.04 0.973 – 1.11 0.246 921 8967 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 1.21 0.946 – 1.54 0.131 59 573 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.07 0.998 – 1.14 0.059 927 9258 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.1 0.97 – 1.25 0.137 259 2546 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.19 1.02 – 1.37 0.0228 185 1791 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.24 1.04 – 1.47 0.0146 135 1236 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.03 0.972 – 1.1 0.288 1073 10435 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.965 0.92 – 1.01 0.146 1850 17482 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.09 0.835 – 1.44 0.513 51 569 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1 0.876 – 1.14 0.992 225 2309 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.974 0.796 – 1.19 0.8 93 962 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.931 0.786 – 1.1 0.412 145 1576 exclusion phecode
650 Normal delivery Pregnancy Complications 1.04 0.985 – 1.09 0.17 1627 15966 exclusion phecode
651 Multiple gestation Pregnancy Complications 0.953 0.847 – 1.07 0.419 298 2887 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.962 0.912 – 1.01 0.151 1461 13926 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.987 0.93 – 1.05 0.659 1165 11472 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 0.826 0.64 – 1.07 0.144 58 613 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.972 0.939 – 1.01 0.114 3649 24708 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.977 0.79 – 1.21 0.833 89 911 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.987 0.942 – 1.04 0.6 1913 15419 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 1 0.914 – 1.1 0.927 450 4469 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.997 0.966 – 1.03 0.855 4508 24659 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.01 0.966 – 1.06 0.662 2141 17778 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.967 0.818 – 1.14 0.69 134 1393 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.977 0.855 – 1.12 0.727 225 2188 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.06 0.806 – 1.39 0.675 51 526 exclusion phecode
679 Complications of in utero procedures Dermatologic 0.907 0.662 – 1.24 0.542 40 454 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.03 1 – 1.06 0.0374 6118 64272 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.03 0.933 – 1.13 0.607 471 4987 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.04 0.939 – 1.14 0.476 442 4579 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.03 0.999 – 1.06 0.0625 4661 49205 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.03 0.998 – 1.06 0.0699 4664 49260 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.03 0.995 – 1.06 0.0975 4624 48875 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.05 0.955 – 1.14 0.339 508 5268 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 0.961 0.903 – 1.02 0.2 1127 11845 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.08 1.03 – 1.13 0.000649 1960 20306 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.02 0.936 – 1.12 0.6 518 5299 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 0.989 0.88 – 1.11 0.85 306 3180 exclusion phecode
687 Symptoms affecting skin Dermatologic 1.1 0.998 – 1.21 0.0547 473 4846 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.954 0.909 – 1 0.0538 1833 18868 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.01 0.89 – 1.16 0.831 239 2477 exclusion phecode
687.3 Changes in skin texture Dermatologic 1.18 0.948 – 1.47 0.138 92 939 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.03 0.989 – 1.07 0.146 2489 25336 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.01 0.983 – 1.04 0.407 4946 50482 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 1.11 0.861 – 1.44 0.411 61 643 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 1.13 0.835 – 1.52 0.436 43 482 exclusion phecode
691 Congenital anomalies of skin Dermatologic 1 0.822 – 1.22 0.995 106 1042 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 1.03 0.956 – 1.1 0.487 855 8502 exclusion phecode
694.1 Vitiligo Dermatologic 1.11 0.858 – 1.44 0.425 54 522 exclusion phecode
694.2 Other dyschromia Dermatologic 1.01 0.932 – 1.09 0.859 683 6728 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.09 0.881 – 1.34 0.441 98 1039 exclusion phecode
695 Erythematous conditions Dermatologic 1.03 0.984 – 1.08 0.199 2021 20675 exclusion phecode
695.1 Toxic erythema Dermatologic 1.1 0.894 – 1.36 0.364 94 963 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.16 0.961 – 1.39 0.124 119 1185 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 1.05 0.791 – 1.38 0.75 51 494 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.3 1.01 – 1.68 0.0401 62 627 exclusion phecode
695.3 Rosacea Dermatologic 0.984 0.869 – 1.11 0.799 278 2762 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.05 0.938 – 1.17 0.408 332 3502 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.09 0.895 – 1.32 0.401 109 1091 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.09 0.965 – 1.23 0.166 273 2909 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 1.02 0.941 – 1.1 0.633 653 6699 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1.03 0.891 – 1.18 0.71 206 2059 exclusion phecode
695.81 Erythema nodosum Dermatologic 1.08 0.85 – 1.38 0.524 69 664 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.05 0.946 – 1.16 0.363 397 4122 exclusion phecode
696 Psoriasis and related disorders Dermatologic 1.04 0.989 – 1.09 0.136 1917 19977 exclusion phecode
696.4 Psoriasis Dermatologic 1.04 0.992 – 1.09 0.1 1873 19512 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 1.04 0.988 – 1.1 0.125 1434 14946 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 1.06 0.972 – 1.15 0.192 605 6215 exclusion phecode
697 Sarcoidosis Dermatologic 0.966 0.879 – 1.06 0.483 472 4745 exclusion phecode
698 Pruritus and related conditions Dermatologic 1.07 0.99 – 1.16 0.0867 667 6823 exclusion phecode
700 Corns and callosities Dermatologic 0.961 0.838 – 1.1 0.569 232 2523 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.04 1 – 1.07 0.0299 4029 40667 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 1.14 0.901 – 1.44 0.279 78 771 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.05 1.01 – 1.1 0.0238 2031 20380 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 1.16 0.883 – 1.52 0.289 52 523 exclusion phecode
701.4 Keloid scar Dermatologic 1.1 0.945 – 1.27 0.224 178 1881 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1.12 1.01 – 1.24 0.0347 397 3970 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.01 0.82 – 1.25 0.902 89 894 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.02 0.989 – 1.05 0.223 4772 47861 exclusion phecode
702.1 Actinic keratosis Dermatologic 1.03 0.987 – 1.08 0.169 2250 22576 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 1.01 0.971 – 1.05 0.63 2696 26994 exclusion phecode
703 Diseases of nail, NOS Dermatologic 0.961 0.852 – 1.08 0.512 298 3128 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.97 0.904 – 1.04 0.389 856 8610 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 1.04 1.01 – 1.07 0.00877 4642 46649 exclusion phecode
704.1 Alopecia Dermatologic 1.15 0.941 – 1.4 0.174 106 1092 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.905 0.701 – 1.17 0.443 66 682 exclusion phecode
705 Disorders of sweat glands Dermatologic 0.92 0.793 – 1.07 0.275 188 1964 exclusion phecode
705.3 Hidradenitis Dermatologic 0.93 0.788 – 1.1 0.388 151 1596 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.04 0.953 – 1.14 0.364 514 5314 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1.02 0.994 – 1.04 0.135 7285 73270 exclusion phecode
706.1 Acne Dermatologic 1.27 0.994 – 1.62 0.0556 66 674 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1.01 0.989 – 1.04 0.293 7710 77410 exclusion phecode
707 Chronic ulcer of skin Dermatologic 0.982 0.932 – 1.03 0.5 1520 17615 exclusion phecode
707.1 Decubitus ulcer Dermatologic 0.949 0.879 – 1.02 0.178 717 8085 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.984 0.947 – 1.02 0.395 2900 29790 exclusion phecode
709.2 Sicca syndrome Dermatologic 0.972 0.88 – 1.07 0.569 414 4244 exclusion phecode
709.3 Systemic sclerosis Dermatologic 0.936 0.786 – 1.12 0.461 137 1519 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.06 0.807 – 1.39 0.678 52 546 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.993 0.952 – 1.04 0.757 2316 23696 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.06 0.964 – 1.16 0.232 482 5410 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.04 0.947 – 1.15 0.399 450 5008 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.03 0.882 – 1.21 0.675 163 1742 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.03 0.922 – 1.16 0.579 315 3600 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 1.08 0.969 – 1.21 0.162 356 3775 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.13 1 – 1.28 0.0492 283 2957 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1 0.792 – 1.27 0.979 68 728 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.05 0.858 – 1.28 0.64 103 1335 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.27 0.924 – 1.75 0.141 40 604 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.02 0.991 – 1.06 0.164 3970 41787 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.03 0.995 – 1.07 0.092 3582 37824 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.987 0.934 – 1.04 0.627 1400 14618 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.969 0.789 – 1.19 0.762 90 978 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.05 0.956 – 1.14 0.33 519 5592 exclusion phecode
716 Other arthropathies Musculoskeletal 1.01 0.996 – 1.02 0.219 32361 233715 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.01 0.97 – 1.05 0.706 2955 30409 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.01 0.992 – 1.03 0.284 13572 137115 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.01 0.994 – 1.02 0.351 31061 230972 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.05 0.982 – 1.12 0.153 977 9967 exclusion phecode
720 Spinal stenosis Musculoskeletal 0.996 0.961 – 1.03 0.85 3216 32603 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 0.997 0.972 – 1.02 0.81 6636 68132 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.992 0.961 – 1.02 0.613 4313 43877 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.942 0.804 – 1.1 0.458 165 1666 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 0.987 0.877 – 1.11 0.836 286 3087 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.03 1 – 1.05 0.0194 7796 79052 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.964 0.873 – 1.06 0.467 451 4531 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.991 0.95 – 1.03 0.663 2418 24782 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 0.834 0.646 – 1.08 0.164 59 603 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.01 0.981 – 1.05 0.414 3841 38828 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.02 0.927 – 1.13 0.659 454 4593 exclusion phecode
723.1 Torticollis Musculoskeletal 1.17 0.946 – 1.45 0.147 93 943 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.04 0.988 – 1.09 0.135 1759 18047 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 0.96 0.861 – 1.07 0.459 352 3413 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.968 0.868 – 1.08 0.565 355 3441 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 0.878 0.667 – 1.16 0.352 53 557 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.07 1.01 – 1.13 0.0184 1378 14329 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1 0.983 – 1.02 0.945 12733 128897 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.989 0.967 – 1.01 0.34 8274 84008 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.981 0.868 – 1.11 0.755 272 2888 exclusion phecode
726.3 Bursitis Musculoskeletal 0.975 0.905 – 1.05 0.512 766 7797 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.998 0.972 – 1.02 0.86 6275 64192 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.989 0.948 – 1.03 0.62 2337 24044 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.905 0.733 – 1.12 0.355 93 936 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.997 0.958 – 1.04 0.878 2662 26905 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.987 0.901 – 1.08 0.772 503 5065 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.978 0.87 – 1.1 0.704 305 3159 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.967 0.802 – 1.17 0.722 121 1260 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.987 0.953 – 1.02 0.484 3322 33245 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.936 0.84 – 1.04 0.233 371 3645 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.982 0.948 – 1.02 0.312 3451 34366 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.99 0.954 – 1.03 0.589 3157 31485 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.01 0.982 – 1.04 0.473 5125 52594 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.05 0.977 – 1.13 0.184 832 8478 exclusion phecode
729.3 Panniculitis Musculoskeletal 1.03 0.836 – 1.27 0.774 89 897 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.01 0.877 – 1.16 0.917 221 2377 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.01 0.872 – 1.16 0.941 208 2259 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.897 0.808 – 0.995 0.0404 411 4122 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.915 0.78 – 1.07 0.272 179 1809 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.804 0.603 – 1.07 0.137 49 510 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.04 0.982 – 1.09 0.202 1484 15373 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.1 0.965 – 1.25 0.154 263 2713 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.01 0.917 – 1.11 0.844 454 4697 exclusion phecode
733.6 Costochondritis Musculoskeletal 0.776 0.632 – 0.953 0.0155 104 1092 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.02 0.956 – 1.09 0.565 1060 10846 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.05 0.863 – 1.29 0.608 113 1059 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1.01 0.984 – 1.03 0.588 8112 81555 exclusion phecode
735.1 Flat foot Musculoskeletal 0.934 0.794 – 1.1 0.411 160 1649 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 0.983 0.952 – 1.01 0.277 4267 43282 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.988 0.938 – 1.04 0.631 1620 16450 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.976 0.922 – 1.03 0.402 1332 13388 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.03 1 – 1.06 0.0458 5624 56022 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1.01 0.959 – 1.07 0.637 1388 14278 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 0.992 0.866 – 1.14 0.907 219 2167 exclusion phecode
737 Curvature of spine Musculoskeletal 0.979 0.914 – 1.05 0.539 898 9643 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.988 0.92 – 1.06 0.73 838 9053 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.01 0.959 – 1.06 0.739 1637 16527 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.02 0.962 – 1.08 0.536 1306 13040 exclusion phecode
739 Contracture of joint Musculoskeletal 1.03 0.935 – 1.14 0.531 428 4299 exclusion phecode
740 Osteoarthrosis Musculoskeletal 0.999 0.985 – 1.01 0.842 23859 203139 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.991 0.975 – 1.01 0.313 15069 148508 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.98 0.957 – 1 0.0849 7825 78780 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.02 0.904 – 1.15 0.736 280 3035 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.962 0.876 – 1.06 0.416 488 5164 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1 0.983 – 1.02 0.741 10506 106995 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.02 0.979 – 1.05 0.388 3084 31423 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 1.16 0.931 – 1.43 0.189 90 910 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.04 0.951 – 1.13 0.403 540 5382 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.918 0.765 – 1.1 0.36 127 1353 exclusion phecode
741.4 Joint effusions Musculoskeletal 1.07 1.01 – 1.14 0.0224 1204 12663 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 0.795 0.639 – 0.989 0.039 89 992 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 1.05 0.779 – 1.42 0.746 45 469 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.953 0.915 – 0.994 0.0237 2481 25174 exclusion phecode
742.1 Loose body in joint Musculoskeletal 0.923 0.821 – 1.04 0.186 301 3000 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.721 0.572 – 0.907 0.00522 80 843 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 0.934 0.846 – 1.03 0.175 441 4396 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.977 0.929 – 1.03 0.353 1734 17634 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.01 0.987 – 1.04 0.315 6099 64789 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.01 0.985 – 1.04 0.37 5109 54673 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.01 0.975 – 1.04 0.708 4374 47171 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1.09 0.985 – 1.2 0.0958 440 4669 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.01 0.912 – 1.11 0.883 410 4525 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.03 0.954 – 1.11 0.435 708 7116 exclusion phecode
745 Pain in joint Musculoskeletal 1.02 0.995 – 1.05 0.114 6830 69998 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.01 0.969 – 1.05 0.614 2397 24908 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.02 0.975 – 1.06 0.411 2254 23395 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.934 0.853 – 1.02 0.138 506 5139 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.97 0.841 – 1.12 0.672 206 2122 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.04 0.989 – 1.1 0.118 1548 16256 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.979 0.82 – 1.17 0.812 137 1477 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.23 0.914 – 1.66 0.171 44 452 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.03 0.906 – 1.16 0.683 263 2692 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.953 0.874 – 1.04 0.28 562 6062 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.934 0.826 – 1.06 0.276 285 2896 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.968 0.829 – 1.13 0.678 174 1693 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.974 0.863 – 1.1 0.672 275 3152 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.01 0.87 – 1.17 0.924 190 2000 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.887 0.7 – 1.12 0.32 74 1022 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.977 0.921 – 1.04 0.443 1218 13429 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.958 0.881 – 1.04 0.316 606 6012 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.931 0.837 – 1.04 0.19 381 3758 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.933 0.812 – 1.07 0.33 212 2069 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.993 0.914 – 1.08 0.859 614 7467 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.937 0.831 – 1.06 0.29 279 3766 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.02 0.897 – 1.15 0.79 267 2972 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.977 0.865 – 1.1 0.713 263 2886 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.01 0.877 – 1.16 0.898 204 2218 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.973 0.832 – 1.14 0.735 163 1829 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.876 0.683 – 1.12 0.295 61 697 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.02 0.84 – 1.24 0.835 115 1095 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.08 0.84 – 1.39 0.547 67 650 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.04 0.837 – 1.29 0.728 89 961 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.92 0.823 – 1.03 0.138 347 3694 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.907 0.777 – 1.06 0.216 176 1785 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.937 0.781 – 1.12 0.48 126 1384 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.955 0.763 – 1.19 0.685 82 895 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.997 0.909 – 1.09 0.951 504 5142 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.05 0.825 – 1.33 0.705 69 707 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.999 0.897 – 1.11 0.985 376 3819 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.931 0.782 – 1.11 0.424 130 1473 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.06 0.82 – 1.38 0.64 51 703 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.849 0.727 – 0.992 0.0393 178 1890 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.89 0.712 – 1.11 0.304 89 846 exclusion phecode
760 Back pain Symptoms 0.988 0.967 – 1.01 0.253 9596 97455 exclusion phecode
761 Cervicalgia Symptoms 1.06 1.01 – 1.12 0.0306 1517 15643 exclusion phecode
764 Sciatica Symptoms 1.02 0.976 – 1.07 0.359 2036 20748 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.02 0.959 – 1.09 0.475 1004 10213 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 0.999 0.914 – 1.09 0.982 540 5536 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.955 0.885 – 1.03 0.236 744 7592 exclusion phecode
771.1 Swelling of limb Symptoms 1 0.972 – 1.04 0.804 3940 40616 exclusion phecode
772 Symptoms of the muscles Symptoms 1.04 0.949 – 1.13 0.426 543 5833 exclusion phecode
773 Pain in limb Symptoms 0.991 0.963 – 1.02 0.516 5267 54170 exclusion phecode
780 Hypothermia/Chills Symptoms 1.05 0.883 – 1.24 0.597 142 1538 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.03 0.978 – 1.08 0.263 1581 16472 exclusion phecode
782.3 Edema Symptoms 1.06 1 – 1.12 0.0417 1335 14501 exclusion phecode
782.6 Pallor and flushing Symptoms 1.01 0.856 – 1.2 0.884 152 1564 exclusion phecode
783 Fever of unknown origin Symptoms 1.01 0.974 – 1.05 0.623 3332 34539 exclusion phecode
785 Abdominal pain Symptoms 0.996 0.985 – 1.01 0.53 34441 265750 exclusion phecode
788 Syncope and collapse Symptoms 0.989 0.967 – 1.01 0.372 7852 80426 exclusion phecode
789 Nausea and vomiting Symptoms 0.982 0.962 – 1 0.0859 9759 100814 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 0.961 0.807 – 1.14 0.655 127 1321 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.03 0.812 – 1.31 0.794 71 730 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.02 0.994 – 1.05 0.124 5591 57759 exclusion phecode
791 Gangrene Symptoms 1.02 0.921 – 1.12 0.756 433 4977 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.822 0.643 – 1.05 0.116 76 794 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.86 0.71 – 1.04 0.121 116 1164 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.01 0.923 – 1.11 0.794 487 4969 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.972 0.797 – 1.18 0.777 105 1044 exclusion phecode
797 Shock Symptoms 1.01 0.847 – 1.21 0.895 130 1384 exclusion phecode
797.1 Cardiogenic shock Symptoms 0.971 0.782 – 1.2 0.787 89 914 exclusion phecode
798 Malaise and fatigue Symptoms 0.953 0.917 – 0.991 0.0151 2862 29878 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 0.955 0.872 – 1.05 0.332 504 5100 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.04 1.01 – 1.06 0.0105 5958 61543 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.04 0.988 – 1.1 0.13 1500 15783 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.9 0.759 – 1.07 0.224 149 1531 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.06 1.01 – 1.11 0.0246 1862 19122 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 1.04 0.956 – 1.12 0.383 662 6832 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.06 1.01 – 1.11 0.0155 1933 19437 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.06 1 – 1.11 0.0328 1617 16177 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 0.96 0.882 – 1.04 0.347 593 6321 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 1.03 1.01 – 1.06 0.0182 7069 72213 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1.01 0.957 – 1.07 0.709 1402 14732 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.02 0.987 – 1.05 0.266 4427 44943 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.09 1.03 – 1.15 0.00304 1335 13755 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 1 0.964 – 1.04 0.935 2977 29712 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.06 0.995 – 1.12 0.071 1160 12087 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.07 0.987 – 1.15 0.101 680 6949 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.08 1.01 – 1.14 0.0173 1129 11573 exclusion phecode
817 Concussion Injuries & Poisonings 0.928 0.807 – 1.07 0.297 225 2183 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.05 0.953 – 1.16 0.328 446 4639 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.02 0.976 – 1.06 0.434 2614 26698 exclusion phecode
823 Torus fracture Injuries & Poisonings 1.04 0.989 – 1.1 0.12 1434 14780 exclusion phecode
830 Dislocation Injuries & Poisonings 0.984 0.939 – 1.03 0.515 1873 18669 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 1 0.984 – 1.02 0.853 13611 135540 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 1.03 0.935 – 1.13 0.55 463 4699 exclusion phecode
840 Sprains and strains Injuries & Poisonings 1.04 0.945 – 1.15 0.394 429 4210 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.99 0.96 – 1.02 0.509 4462 46242 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.09 0.911 – 1.3 0.347 136 1393 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.07 0.964 – 1.18 0.207 415 4404 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.991 0.939 – 1.05 0.728 1455 16476 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.997 0.936 – 1.06 0.937 1027 10981 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.991 0.952 – 1.03 0.671 2651 27547 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 0.994 0.955 – 1.03 0.756 2709 28595 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.16 0.894 – 1.51 0.259 59 623 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.05 1.01 – 1.09 0.0142 3050 31405 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.15 1.01 – 1.31 0.0402 236 2421 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1.11 0.947 – 1.29 0.204 171 1762 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.03 0.99 – 1.07 0.137 2518 26039 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.03 0.884 – 1.19 0.724 191 1954 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 1.07 0.817 – 1.41 0.616 61 608 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1 0.97 – 1.04 0.855 3651 36621 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.803 0.588 – 1.1 0.167 47 482 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.01 0.804 – 1.26 0.95 84 825 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.05 0.894 – 1.24 0.526 153 1571 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 0.988 0.895 – 1.09 0.815 442 4291 exclusion phecode
873 Broken tooth Injuries & Poisonings 1.25 1.07 – 1.45 0.00371 187 2009 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.11 0.935 – 1.31 0.239 135 1545 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.04 0.873 – 1.23 0.677 136 1409 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 0.962 0.905 – 1.02 0.216 1122 11780 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.02 0.983 – 1.05 0.343 3664 37859 exclusion phecode
916 Contusion Injuries & Poisonings 1.04 0.983 – 1.11 0.168 1218 12820 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.954 0.805 – 1.13 0.585 152 1570 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.972 0.869 – 1.09 0.617 344 3399 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 1 0.875 – 1.15 0.955 224 2212 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.973 0.927 – 1.02 0.264 1789 18495 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.11 0.956 – 1.28 0.175 206 1952 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.873 0.7 – 1.09 0.227 84 935 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.974 0.886 – 1.07 0.593 466 4849 exclusion phecode
947 Urticaria Injuries & Poisonings 0.976 0.873 – 1.09 0.665 324 3235 exclusion phecode
949 Allergies, other Injuries & Poisonings 0.974 0.871 – 1.09 0.644 339 3518 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.19 1.07 – 1.33 0.00134 364 3760 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.02 0.887 – 1.16 0.825 220 2344 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.02 0.923 – 1.13 0.698 425 4434 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 0.95 0.706 – 1.28 0.732 46 497 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.935 0.725 – 1.21 0.605 65 674 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1 0.988 – 1.02 0.626 15403 157234 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1 0.984 – 1.02 0.82 13487 137920 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.05 0.94 – 1.17 0.389 343 3614 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.974 0.902 – 1.05 0.501 713 7389 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.02 0.906 – 1.14 0.764 302 3223 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.03 0.916 – 1.16 0.627 299 3162 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.21 1.03 – 1.41 0.0168 182 1945 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.949 0.828 – 1.09 0.45 220 2509 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.963 0.839 – 1.1 0.589 213 2450 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.01 0.981 – 1.04 0.505 5173 52759 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.03 0.963 – 1.1 0.381 935 9799 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.03 0.929 – 1.14 0.595 407 4153 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1 0.897 – 1.12 0.951 335 3565 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.09 0.991 – 1.2 0.0743 436 4494 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.949 0.864 – 1.04 0.27 486 5029 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.02 0.974 – 1.08 0.345 1637 17108 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.15 0.975 – 1.35 0.0982 161 1684 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.03 0.904 – 1.18 0.64 226 2432 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.974 0.769 – 1.23 0.826 72 769 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.03 0.833 – 1.27 0.798 89 951 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.935 0.748 – 1.17 0.558 82 930 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.816 0.625 – 1.07 0.137 52 563 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.93 0.687 – 1.26 0.637 46 489 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.06 0.917 – 1.23 0.42 189 2029 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.01 0.924 – 1.1 0.891 581 6087 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.05 0.898 – 1.23 0.536 174 1778 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.04 0.807 – 1.35 0.754 58 556 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 0.964 0.767 – 1.21 0.756 93 949 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.915 0.733 – 1.14 0.432 90 981 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.979 0.776 – 1.24 0.861 77 794 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 0.985 0.946 – 1.03 0.457 2640 27429 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 0.975 0.936 – 1.02 0.22 2530 26833 exclusion phecode
994.2 Sepsis Injuries & Poisonings 0.975 0.936 – 1.02 0.22 2530 26833 exclusion phecode
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