Departments of Anesthesiology and Biostatistics | University of Michigan

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ExPRSweb

Compare evaluated PRS models, inspect score-level performance, and follow results into PheWAS analyses.

Scores Estimated glomerular filtration rate based on creatinine UK Biobank (UKB) PheWAS analysis

Estimated glomerular filtration rate based on creatinine — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID exprsweb-egfr-creatine-egfrcrea-overall-iv-2gc-lassosum-ukb-20211120Legacy LASSOSUMlassosumLarge GWAS

Evaluation cohort: UK Biobank (UKB).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: study-defined normal-range subset.

For this ExPRS, the exclusion sensitivity scan keeps only the study-defined normal-range subset for Estimated glomerular filtration rate based on creatinine before rerunning the PheWAS. The preserved release does not include numeric bounds for this trait. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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Signal overview

The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.

125 rows visible 14 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 0.976 0.954 – 0.997 0.0274 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 0.961 0.923 – 0.999 0.0469 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.933 0.861 – 1.01 0.0915 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 1 0.933 – 1.07 0.977 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1 0.774 – 1.3 0.981 55 550 all phecode
010 Tuberculosis Infectious Diseases 0.863 0.734 – 1.01 0.0732 166 1659 all phecode
038 Septicemia Infectious Diseases 1 0.97 – 1.03 0.932 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 0.967 0.9 – 1.04 0.349 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 0.97 0.883 – 1.07 0.524 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 0.995 0.977 – 1.01 0.632 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 0.979 0.944 – 1.02 0.267 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 1 0.953 – 1.06 0.909 1641 16433 all phecode
041.4 E. coli Infectious Diseases 0.995 0.956 – 1.03 0.797 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 1.04 0.944 – 1.16 0.398 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.968 0.779 – 1.2 0.773 95 949 all phecode
054 Herpes simplex Infectious Diseases 1.05 0.909 – 1.21 0.523 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 1.01 0.928 – 1.1 0.808 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 1.1 0.87 – 1.4 0.414 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.06 0.889 – 1.26 0.521 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.02 0.89 – 1.16 0.809 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 0.902 0.797 – 1.02 0.0978 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 0.88 0.797 – 0.972 0.0113 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.874 0.738 – 1.04 0.12 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.854 0.703 – 1.04 0.111 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 1.01 0.944 – 1.08 0.8 1004 10036 all phecode
079 Viral infection Infectious Diseases 0.979 0.942 – 1.02 0.298 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 0.849 0.655 – 1.1 0.219 64 640 all phecode
080 Postoperative infection Infectious Diseases 1.02 0.991 – 1.05 0.16 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.03 0.986 – 1.07 0.202 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.03 0.804 – 1.33 0.804 71 709 all phecode
1000 Burns Injuries & Poisonings 0.975 0.894 – 1.06 0.568 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 0.983 0.926 – 1.04 0.574 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 0.983 0.956 – 1.01 0.222 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.05 0.935 – 1.19 0.39 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 1.04 0.982 – 1.09 0.193 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 1.01 0.892 – 1.15 0.825 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 1.02 0.901 – 1.16 0.74 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.03 0.963 – 1.1 0.406 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 1 0.981 – 1.03 0.8 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 0.977 0.951 – 1 0.0917 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.01 0.989 – 1.03 0.341 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 1.07 0.879 – 1.31 0.49 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.07 0.953 – 1.2 0.252 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.05 0.807 – 1.36 0.727 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 1.01 0.976 – 1.04 0.656 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1 0.987 – 1.02 0.657 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.916 0.81 – 1.04 0.159 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 0.912 0.807 – 1.03 0.143 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.841 0.659 – 1.07 0.162 74 756 all phecode
110.12 Althete's foot Infectious Diseases 0.936 0.79 – 1.11 0.447 141 1410 all phecode
112 Candidiasis Infectious Diseases 0.97 0.928 – 1.01 0.182 2126 21275 all phecode
117 Mycoses Infectious Diseases 0.952 0.841 – 1.08 0.431 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 0.869 0.74 – 1.02 0.0884 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 0.962 0.766 – 1.21 0.741 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 0.855 0.668 – 1.09 0.214 69 689 all phecode
134 Helminthiases Infectious Diseases 1 0.832 – 1.2 0.997 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1 0.817 – 1.22 0.999 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.02 0.887 – 1.17 0.773 205 2050 all phecode
145 Cancer of mouth Neoplasms 1.06 0.98 – 1.15 0.138 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 1.06 0.945 – 1.19 0.316 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.12 0.918 – 1.37 0.26 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.04 0.782 – 1.38 0.802 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.05 0.967 – 1.14 0.247 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 1.06 0.937 – 1.21 0.341 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 1.04 0.918 – 1.18 0.529 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 1.16 0.874 – 1.53 0.306 57 570 all phecode
150 Cancer of esophagus Neoplasms 0.989 0.919 – 1.06 0.773 762 7630 all phecode
151 Cancer of stomach Neoplasms 0.975 0.894 – 1.06 0.563 569 5696 all phecode
153 Colorectal cancer Neoplasms 1.01 0.983 – 1.05 0.382 4580 45799 all phecode
153.2 Colon cancer Neoplasms 1.01 0.976 – 1.05 0.504 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.01 0.962 – 1.05 0.794 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.05 0.946 – 1.16 0.372 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.06 0.902 – 1.25 0.474 158 1580 all phecode
157 Pancreatic cancer Neoplasms 1.01 0.936 – 1.1 0.73 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.05 0.982 – 1.12 0.158 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.01 0.981 – 1.04 0.537 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.99 0.854 – 1.15 0.89 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1 0.87 – 1.16 0.964 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.951 0.818 – 1.11 0.513 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 0.982 0.759 – 1.27 0.891 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 1.01 0.976 – 1.05 0.452 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.02 0.973 – 1.06 0.478 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 1.01 0.915 – 1.12 0.84 437 4364 all phecode
170.1 Bone cancer Neoplasms 1.03 0.866 – 1.24 0.707 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 1 0.896 – 1.13 0.942 331 3303 all phecode
172 Skin cancer Neoplasms 1 0.985 – 1.02 0.732 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.999 0.96 – 1.04 0.953 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 1 0.961 – 1.04 0.988 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1 0.984 – 1.02 0.711 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.01 0.934 – 1.1 0.778 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.969 0.833 – 1.13 0.686 181 1818 all phecode
174 Breast cancer Neoplasms 1.02 0.997 – 1.03 0.0936 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 1.01 0.996 – 1.03 0.135 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.01 0.996 – 1.03 0.132 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.09 0.904 – 1.32 0.357 115 1148 all phecode
175 Acquired absence of breast Neoplasms 1.04 1 – 1.09 0.0467 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 1.01 0.966 – 1.06 0.669 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 1.06 0.933 – 1.2 0.384 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1 0.959 – 1.05 0.883 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 0.996 0.94 – 1.05 0.882 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 1.01 0.959 – 1.07 0.64 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.01 0.943 – 1.08 0.833 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.02 0.951 – 1.09 0.63 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.04 0.923 – 1.16 0.554 305 3049 all phecode
185 Cancer of prostate Neoplasms 1.01 0.983 – 1.04 0.506 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 0.975 0.885 – 1.07 0.607 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.938 0.741 – 1.19 0.593 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.941 0.833 – 1.06 0.324 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.11 0.913 – 1.35 0.298 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.994 0.962 – 1.03 0.693 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.02 0.954 – 1.08 0.617 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.02 0.956 – 1.09 0.541 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.989 0.77 – 1.27 0.931 66 660 all phecode
189.2 Cancer of bladder Neoplasms 0.974 0.934 – 1.02 0.219 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.969 0.927 – 1.01 0.165 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.05 0.878 – 1.25 0.619 144 1439 all phecode
190 Cancer of eye Neoplasms 1.16 0.985 – 1.36 0.0756 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.02 0.946 – 1.11 0.573 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1 0.921 – 1.09 0.944 566 5650 all phecode
191.11 Cancer of brain Neoplasms 1.02 0.937 – 1.12 0.604 525 5240 all phecode
193 Thyroid cancer Neoplasms 1.11 0.997 – 1.24 0.0576 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 0.906 0.738 – 1.11 0.345 95 949 all phecode
195 Cancer, suspected or other Neoplasms 1 0.989 – 1.02 0.583 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.01 0.99 – 1.02 0.486 16267 159497 all phecode
197 Chemotherapy Neoplasms 1.01 0.996 – 1.03 0.142 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 1.02 0.996 – 1.04 0.12 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.02 0.994 – 1.05 0.117 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.985 0.944 – 1.03 0.507 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.999 0.948 – 1.05 0.961 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.01 0.968 – 1.05 0.697 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.981 0.914 – 1.05 0.596 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 0.978 0.935 – 1.02 0.322 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.01 0.871 – 1.17 0.886 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 0.946 0.896 – 0.999 0.0455 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 0.837 0.678 – 1.03 0.0956 95 950 all phecode
200 Myeloproliferative disease Neoplasms 0.978 0.916 – 1.04 0.499 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 1.01 0.907 – 1.12 0.913 387 3867 all phecode
201 Hodgkin's disease Neoplasms 0.952 0.837 – 1.08 0.449 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.968 0.927 – 1.01 0.148 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.954 0.908 – 1 0.0572 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 0.917 0.823 – 1.02 0.116 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 0.956 0.877 – 1.04 0.299 581 5824 all phecode
204 Leukemia Neoplasms 0.957 0.91 – 1.01 0.0909 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 0.959 0.88 – 1.05 0.344 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.991 0.747 – 1.32 0.953 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.947 0.864 – 1.04 0.248 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 0.953 0.866 – 1.05 0.332 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.905 0.806 – 1.02 0.0917 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.06 0.898 – 1.26 0.477 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 0.916 0.839 – 0.999 0.0478 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 0.99 0.975 – 1 0.165 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.02 0.951 – 1.08 0.642 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.02 0.988 – 1.05 0.248 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.929 0.833 – 1.04 0.184 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.997 0.887 – 1.12 0.959 318 3187 all phecode
214 Lipoma Neoplasms 1.02 0.998 – 1.05 0.0714 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.03 1 – 1.07 0.0353 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.957 0.9 – 1.02 0.167 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 0.994 0.971 – 1.02 0.605 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.986 0.907 – 1.07 0.738 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 0.967 0.887 – 1.05 0.44 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 1 0.983 – 1.02 0.723 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 1 0.983 – 1.02 0.737 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.06 0.951 – 1.18 0.29 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 1.02 0.969 – 1.08 0.42 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.933 0.811 – 1.07 0.327 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.952 0.813 – 1.12 0.542 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.04 0.884 – 1.22 0.655 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 1.05 0.877 – 1.26 0.587 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.21 0.938 – 1.55 0.145 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.988 0.919 – 1.06 0.746 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.991 0.92 – 1.07 0.807 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.785 0.6 – 1.03 0.0767 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.916 0.807 – 1.04 0.171 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.01 0.942 – 1.08 0.773 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.07 0.919 – 1.24 0.395 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.01 0.909 – 1.12 0.836 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.991 0.88 – 1.12 0.881 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.02 0.967 – 1.07 0.497 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.02 0.975 – 1.06 0.446 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.984 0.905 – 1.07 0.699 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.03 0.972 – 1.1 0.29 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.04 0.944 – 1.14 0.433 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.01 0.933 – 1.09 0.803 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.969 0.924 – 1.02 0.2 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 0.967 0.878 – 1.07 0.504 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.06 0.863 – 1.3 0.587 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 0.806 0.675 – 0.962 0.0168 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 0.974 0.958 – 0.991 0.00282 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.98 0.921 – 1.04 0.522 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.92 0.752 – 1.13 0.419 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.971 0.954 – 0.988 0.00095 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 0.984 0.872 – 1.11 0.798 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.957 0.833 – 1.1 0.541 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.962 0.836 – 1.11 0.59 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.02 0.925 – 1.14 0.639 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.01 1 – 1.03 0.0527 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.987 0.949 – 1.03 0.503 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.04 0.909 – 1.19 0.567 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.885 0.702 – 1.11 0.297 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.985 0.896 – 1.08 0.75 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 0.937 0.794 – 1.1 0.436 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.02 1 – 1.03 0.0294 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.07 0.869 – 1.31 0.534 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.975 0.842 – 1.13 0.733 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.03 0.967 – 1.1 0.336 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 0.997 0.91 – 1.09 0.953 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.03 0.955 – 1.12 0.413 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.968 0.854 – 1.1 0.617 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.11 1 – 1.22 0.0468 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.91 0.762 – 1.09 0.301 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.04 0.932 – 1.16 0.483 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.01 0.955 – 1.07 0.716 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.01 0.948 – 1.08 0.69 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.03 0.957 – 1.1 0.47 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.02 0.951 – 1.1 0.523 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.02 0.857 – 1.22 0.815 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.06 0.978 – 1.15 0.156 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.04 0.893 – 1.21 0.61 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.01 0.815 – 1.26 0.916 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.03 0.907 – 1.17 0.639 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.17 0.946 – 1.46 0.146 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.908 0.77 – 1.07 0.247 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.06 0.979 – 1.15 0.15 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.14 0.983 – 1.33 0.0812 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.11 0.911 – 1.35 0.303 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.12 0.887 – 1.42 0.332 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.985 0.885 – 1.1 0.787 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.985 0.884 – 1.1 0.779 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.13 0.985 – 1.29 0.0813 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.13 0.979 – 1.31 0.0946 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 0.845 0.717 – 0.996 0.0452 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.861 0.728 – 1.02 0.0837 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.974 0.799 – 1.19 0.796 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 0.998 0.841 – 1.18 0.981 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.843 0.732 – 0.972 0.0185 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 1.18 0.892 – 1.55 0.25 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 1.03 0.957 – 1.11 0.44 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 0.998 0.94 – 1.06 0.944 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.967 0.898 – 1.04 0.381 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.02 0.922 – 1.12 0.74 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.814 0.647 – 1.02 0.0795 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.05 0.92 – 1.19 0.484 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 0.944 0.843 – 1.06 0.323 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.03 0.92 – 1.16 0.587 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.02 0.898 – 1.15 0.796 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.02 0.883 – 1.18 0.793 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 0.91 0.752 – 1.1 0.335 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.05 0.824 – 1.35 0.676 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.07 0.911 – 1.26 0.402 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.08 0.907 – 1.28 0.391 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1 0.99 – 1.01 0.85 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1 0.99 – 1.01 0.863 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1 0.989 – 1.01 0.882 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.854 0.652 – 1.12 0.253 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.06 0.905 – 1.25 0.456 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.955 0.832 – 1.1 0.511 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.946 0.914 – 0.978 0.00121 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 0.95 0.915 – 0.985 0.00571 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.892 0.735 – 1.08 0.248 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.941 0.866 – 1.02 0.149 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.945 0.866 – 1.03 0.199 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1 0.959 – 1.05 0.883 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 1.03 0.948 – 1.11 0.507 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.06 0.955 – 1.18 0.275 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.958 0.902 – 1.02 0.155 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.995 0.849 – 1.17 0.947 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 0.987 0.964 – 1.01 0.306 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 0.986 0.955 – 1.02 0.389 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.04 0.909 – 1.19 0.577 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 0.973 0.927 – 1.02 0.258 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 0.927 0.868 – 0.99 0.023 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.05 0.994 – 1.11 0.0804 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.99 0.932 – 1.05 0.756 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 1 0.939 – 1.07 0.987 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 0.911 0.749 – 1.11 0.354 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 0.98 0.942 – 1.02 0.303 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 0.968 0.879 – 1.07 0.508 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 0.958 0.795 – 1.15 0.65 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1 0.933 – 1.07 0.995 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.889 0.798 – 0.991 0.0344 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.958 0.84 – 1.09 0.525 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.955 0.723 – 1.26 0.747 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.997 0.977 – 1.02 0.747 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 0.999 0.979 – 1.02 0.89 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 0.913 0.725 – 1.15 0.439 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.975 0.76 – 1.25 0.84 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.921 0.808 – 1.05 0.218 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 0.861 0.746 – 0.995 0.0424 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.808 0.679 – 0.962 0.0167 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 1 0.878 – 1.14 0.989 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 0.996 0.972 – 1.02 0.722 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.991 0.968 – 1.02 0.474 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.08 0.975 – 1.19 0.143 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 0.97 0.912 – 1.03 0.328 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 0.964 0.905 – 1.03 0.246 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 0.988 0.916 – 1.06 0.746 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.959 0.821 – 1.12 0.596 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 0.936 0.806 – 1.09 0.384 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 1.18 0.897 – 1.54 0.241 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 0.987 0.835 – 1.17 0.874 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1.04 0.802 – 1.35 0.763 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.996 0.806 – 1.23 0.972 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 0.942 0.789 – 1.13 0.512 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.943 0.773 – 1.15 0.567 103 1059 all phecode
284 Aplastic anemia Hematopoietic 0.935 0.848 – 1.03 0.18 435 4357 all phecode
285 Other anemias Hematopoietic 0.982 0.963 – 1 0.0533 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.99 0.872 – 1.12 0.879 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 0.931 0.859 – 1.01 0.0769 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.919 0.83 – 1.02 0.105 414 4147 all phecode
286 Coagulation defects Hematopoietic 0.94 0.878 – 1.01 0.0779 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 0.966 0.877 – 1.06 0.479 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 1.04 0.846 – 1.28 0.701 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.977 0.867 – 1.1 0.706 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 0.864 0.665 – 1.12 0.271 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.859 0.689 – 1.07 0.178 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.922 0.83 – 1.02 0.132 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.02 0.965 – 1.07 0.557 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1 0.843 – 1.2 0.956 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 1.24 0.954 – 1.62 0.108 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 1.02 0.965 – 1.07 0.52 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.05 0.948 – 1.16 0.364 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.19 0.943 – 1.5 0.143 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 0.997 0.964 – 1.03 0.868 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 0.998 0.962 – 1.04 0.921 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 0.999 0.963 – 1.04 0.971 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 0.796 0.63 – 1.01 0.0562 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.01 0.938 – 1.08 0.844 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.02 0.904 – 1.16 0.716 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 0.992 0.953 – 1.03 0.715 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 0.923 0.843 – 1.01 0.0866 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 0.955 0.848 – 1.08 0.453 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 0.884 0.71 – 1.1 0.271 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.01 0.966 – 1.06 0.584 1929 19281 all phecode
290.1 Dementias Mental Disorders 1.02 0.955 – 1.09 0.561 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 0.967 0.875 – 1.07 0.512 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 0.985 0.852 – 1.14 0.836 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.957 0.883 – 1.04 0.291 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.25 0.976 – 1.61 0.0762 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.02 0.95 – 1.09 0.605 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.01 0.852 – 1.21 0.876 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.03 0.908 – 1.16 0.683 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 1.03 0.936 – 1.14 0.537 436 4376 all phecode
292 Neurological disorders Mental Disorders 1.02 0.986 – 1.05 0.299 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.02 0.968 – 1.08 0.453 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.944 0.813 – 1.1 0.45 190 1907 all phecode
292.3 Memory loss Mental Disorders 1.02 0.947 – 1.11 0.561 696 6978 all phecode
292.4 Altered mental status Mental Disorders 1.03 0.99 – 1.08 0.13 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 1.08 0.962 – 1.22 0.188 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 1.02 0.973 – 1.07 0.43 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.05 0.977 – 1.12 0.192 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.03 0.959 – 1.11 0.416 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 1.08 0.988 – 1.17 0.0919 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 0.999 0.857 – 1.17 0.993 178 1780 all phecode
295.3 Psychosis Mental Disorders 0.937 0.801 – 1.1 0.413 169 1710 all phecode
296 Mood disorders Mental Disorders 1 0.982 – 1.02 0.955 12372 123822 all phecode
296.1 Bipolar Mental Disorders 1.03 0.972 – 1.1 0.287 1059 10599 all phecode
296.2 Depression Mental Disorders 0.999 0.98 – 1.02 0.947 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 1.04 0.932 – 1.16 0.495 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.953 0.849 – 1.07 0.41 311 3070 all phecode
300 Anxiety disorders Mental Disorders 1.01 0.981 – 1.03 0.676 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 1.01 0.984 – 1.04 0.44 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 0.918 0.774 – 1.09 0.33 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.996 0.922 – 1.08 0.917 707 7065 all phecode
300.13 Phobia Mental Disorders 1.03 0.943 – 1.13 0.486 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.977 0.823 – 1.16 0.791 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 1.06 0.807 – 1.4 0.669 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 0.821 0.679 – 0.994 0.043 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.954 0.785 – 1.16 0.634 113 1129 all phecode
301 Personality disorders Mental Disorders 0.945 0.844 – 1.06 0.328 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.865 0.719 – 1.04 0.122 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 1.1 0.972 – 1.24 0.132 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.983 0.893 – 1.08 0.721 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 0.982 0.88 – 1.1 0.749 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 0.927 0.772 – 1.11 0.418 123 1229 all phecode
304 Adjustment reaction Mental Disorders 0.982 0.87 – 1.11 0.768 293 2936 all phecode
305.2 Eating disorder Mental Disorders 1.3 1.05 – 1.62 0.0186 90 900 all phecode
306 Other mental disorder Mental Disorders 1.02 1.01 – 1.03 0.00291 28056 230087 all phecode
306.9 Tension headache Mental Disorders 1.06 0.948 – 1.19 0.296 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 0.969 0.769 – 1.22 0.791 76 770 all phecode
313.3 Autism Mental Disorders 0.915 0.696 – 1.2 0.526 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 1.04 0.931 – 1.16 0.484 351 3517 all phecode
315.1 Learning disorder Mental Disorders 1.05 0.889 – 1.24 0.566 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 1.07 0.859 – 1.34 0.533 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 1.01 0.982 – 1.04 0.495 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.28 0.995 – 1.65 0.0548 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 1.01 0.989 – 1.03 0.454 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 1.01 0.99 – 1.03 0.287 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.02 0.953 – 1.1 0.543 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 1.03 1.01 – 1.04 0.000481 19359 185465 all phecode
320 Meningitis Neurological 0.992 0.898 – 1.1 0.872 444 4447 all phecode
323 Encephalitis Neurological 0.971 0.869 – 1.08 0.603 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 1 0.795 – 1.26 0.999 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.1 0.97 – 1.24 0.141 292 2916 all phecode
327 Sleep disorders Neurological 0.971 0.914 – 1.03 0.348 1164 11659 all phecode
327.3 Sleep apnea Neurological 0.976 0.946 – 1.01 0.123 4428 44318 all phecode
327.4 Insomnia Neurological 1.01 0.865 – 1.18 0.898 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 1.04 0.875 – 1.22 0.687 136 1390 all phecode
331 Other cerebral degenerations Neurological 0.994 0.935 – 1.06 0.834 1142 11416 all phecode
331.1 Hydrocephalus Neurological 1 0.914 – 1.1 0.973 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 0.948 0.858 – 1.05 0.288 430 4298 all phecode
332 Parkinson's disease Neurological 0.999 0.94 – 1.06 0.972 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.08 1.01 – 1.16 0.0311 894 8954 all phecode
333.1 Essential tremor Neurological 1.08 0.934 – 1.24 0.314 216 2157 all phecode
333.2 Myoclonus Neurological 0.898 0.725 – 1.11 0.322 96 958 all phecode
333.4 Torsion dystonia Neurological 1.16 1.02 – 1.32 0.0265 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 0.985 0.938 – 1.03 0.53 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 1.01 0.836 – 1.22 0.905 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 0.973 0.853 – 1.11 0.679 245 2446 all phecode
335 Multiple sclerosis Neurological 1.03 0.974 – 1.09 0.296 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 0.99 0.874 – 1.12 0.874 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.08 0.852 – 1.36 0.534 72 719 all phecode
338 Pain Neurological 0.99 0.919 – 1.07 0.783 768 7692 all phecode
338.1 Acute pain Neurological 1.07 0.962 – 1.18 0.221 394 3937 all phecode
338.2 Chronic pain Neurological 0.949 0.852 – 1.06 0.338 380 3817 all phecode
339 Other headache syndromes Neurological 0.999 0.976 – 1.02 0.953 7819 78241 all phecode
340 Migraine Neurological 0.957 0.921 – 0.995 0.0254 2860 28602 all phecode
340.1 Migrain with aura Neurological 0.917 0.798 – 1.06 0.228 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.963 0.844 – 1.1 0.582 252 2535 all phecode
342 Hemiplegia Neurological 1.06 1.01 – 1.12 0.027 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 1.06 0.897 – 1.26 0.49 145 1450 all phecode
344 Other paralytic syndromes Neurological 0.998 0.921 – 1.08 0.969 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.01 0.979 – 1.04 0.617 5023 50270 all phecode
345.1 Epilepsy Neurological 0.996 0.928 – 1.07 0.912 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 1 0.908 – 1.1 0.973 439 4385 all phecode
345.12 Partial epilepsy Neurological 1.01 0.891 – 1.15 0.871 277 2776 all phecode
345.3 Convulsions Neurological 0.988 0.946 – 1.03 0.584 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.07 0.902 – 1.26 0.445 144 1438 all phecode
348 Other conditions of brain Neurological 0.95 0.883 – 1.02 0.174 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 0.945 0.833 – 1.07 0.38 268 2678 all phecode
348.4 Cerebral cysts Neurological 0.993 0.832 – 1.18 0.934 133 1350 all phecode
348.7 Coma Neurological 1.1 0.987 – 1.22 0.0864 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 0.916 0.804 – 1.04 0.192 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 1.07 0.967 – 1.19 0.188 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.937 0.837 – 1.05 0.256 342 3414 all phecode
350 Abnormal movement Neurological 1.01 0.971 – 1.05 0.614 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 1.03 0.963 – 1.11 0.371 887 8852 all phecode
350.2 Abnormality of gait Neurological 1.01 0.955 – 1.06 0.83 1596 15969 all phecode
350.3 Lack of coordination Neurological 0.987 0.885 – 1.1 0.816 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.07 0.817 – 1.41 0.606 54 540 all phecode
351 Other peripheral nerve disorders Neurological 0.984 0.966 – 1 0.0848 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 0.954 0.903 – 1.01 0.101 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.896 0.815 – 0.986 0.0238 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 0.992 0.925 – 1.06 0.824 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 0.988 0.929 – 1.05 0.692 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 1.04 0.865 – 1.25 0.669 114 1138 all phecode
353.2 Nerve root lesions Neurological 0.834 0.633 – 1.1 0.197 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.96 0.81 – 1.14 0.639 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 0.952 0.9 – 1.01 0.0873 1361 13648 all phecode
358 Myoneural disorders Neurological 0.929 0.806 – 1.07 0.315 211 2109 all phecode
358.1 Myasthenia gravis Neurological 0.934 0.804 – 1.08 0.367 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.925 0.841 – 1.02 0.112 465 4646 all phecode
359.1 Muscular dystrophies Neurological 1.03 0.859 – 1.24 0.743 122 1219 all phecode
359.2 Myopathy Neurological 0.905 0.813 – 1.01 0.0704 360 3597 all phecode
360 Disorders of the globe Sense Organs 0.915 0.817 – 1.03 0.125 337 3367 all phecode
360.2 Progressive myopia Sense Organs 0.873 0.764 – 0.998 0.0463 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 0.988 0.953 – 1.02 0.502 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.974 0.922 – 1.03 0.354 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 1.21 0.957 – 1.53 0.112 68 680 all phecode
362 Other retinal disorders Sense Organs 1.02 0.989 – 1.06 0.186 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.01 0.968 – 1.06 0.616 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.01 0.968 – 1.06 0.621 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.901 0.767 – 1.06 0.202 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 0.918 0.748 – 1.13 0.412 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.05 0.982 – 1.13 0.144 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 1.11 0.949 – 1.29 0.195 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.16 0.919 – 1.46 0.211 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.02 0.848 – 1.23 0.815 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.991 0.846 – 1.16 0.915 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 1.03 0.8 – 1.32 0.834 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.02 0.937 – 1.1 0.686 647 6485 all phecode
364.1 Corneal opacity Sense Organs 1.02 0.821 – 1.26 0.869 90 910 all phecode
364.2 Corneal edema Sense Organs 1.16 0.923 – 1.46 0.2 79 800 all phecode
364.4 Corneal degenerations Sense Organs 0.978 0.844 – 1.13 0.762 201 2017 all phecode
364.41 Keratoconus Sense Organs 0.896 0.723 – 1.11 0.314 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 1.01 0.879 – 1.17 0.863 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 1.16 0.954 – 1.42 0.135 100 1000 all phecode
365 Glaucoma Sense Organs 1.02 0.989 – 1.05 0.198 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 1 0.941 – 1.07 0.906 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.01 0.944 – 1.07 0.835 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.983 0.91 – 1.06 0.654 698 6996 all phecode
366 Cataract Sense Organs 0.997 0.983 – 1.01 0.716 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 0.982 0.765 – 1.26 0.885 69 700 all phecode
366.2 Senile cataract Sense Organs 1 0.98 – 1.03 0.807 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 0.881 0.718 – 1.08 0.224 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.986 0.945 – 1.03 0.497 2408 24092 all phecode
367.1 Myopia Sense Organs 0.984 0.929 – 1.04 0.596 1251 12519 all phecode
367.2 Astigmatism Sense Organs 0.953 0.822 – 1.1 0.519 190 1899 all phecode
367.8 Hypermetropia Sense Organs 1.02 0.897 – 1.16 0.776 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 0.976 0.903 – 1.06 0.543 719 7198 all phecode
368 Visual disturbances Sense Organs 1.02 0.98 – 1.06 0.36 2962 29648 all phecode
368.1 Amblyopia Sense Organs 1.06 0.969 – 1.16 0.2 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.987 0.914 – 1.07 0.734 727 7288 all phecode
368.3 Anisometropia Sense Organs 0.888 0.753 – 1.05 0.159 154 1548 all phecode
368.4 Visual field defects Sense Organs 0.965 0.861 – 1.08 0.545 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 1.02 0.942 – 1.11 0.578 612 6115 all phecode
369 Infection of the eye Sense Organs 0.974 0.893 – 1.06 0.552 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 1.03 0.86 – 1.24 0.743 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 1.04 0.903 – 1.19 0.597 213 2128 all phecode
370 Keratitis Sense Organs 1.08 0.956 – 1.23 0.207 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 1.3 1.09 – 1.56 0.00404 141 1408 all phecode
371 Inflammation of the eye Sense Organs 0.999 0.963 – 1.04 0.966 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.03 0.942 – 1.14 0.484 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 1.01 0.966 – 1.05 0.723 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 0.935 0.867 – 1.01 0.0785 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 1.02 0.992 – 1.05 0.156 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 0.985 0.924 – 1.05 0.644 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 1.01 0.961 – 1.06 0.721 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 0.975 0.934 – 1.02 0.259 2204 22031 all phecode
375.2 Epiphora Sense Organs 1 0.936 – 1.07 0.948 898 8969 all phecode
376 Disorders of the orbit Sense Organs 0.885 0.708 – 1.11 0.285 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.898 0.804 – 1 0.0551 361 3618 all phecode
377.1 Optic atrophy Sense Organs 0.853 0.65 – 1.12 0.253 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.907 0.755 – 1.09 0.296 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.01 0.96 – 1.07 0.614 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.03 0.964 – 1.1 0.365 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.974 0.847 – 1.12 0.711 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 1.02 0.901 – 1.16 0.726 275 2755 all phecode
379 Other disorders of eye Sense Organs 0.987 0.954 – 1.02 0.438 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 1.01 0.952 – 1.06 0.819 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.966 0.921 – 1.01 0.169 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.15 0.902 – 1.46 0.264 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.02 0.925 – 1.13 0.654 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.18 1 – 1.38 0.0435 169 1690 all phecode
380 Disorders of external ear Sense Organs 0.982 0.906 – 1.07 0.665 642 6413 all phecode
380.1 Otitis externa Sense Organs 0.978 0.893 – 1.07 0.633 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 0.927 0.832 – 1.03 0.171 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.981 0.938 – 1.03 0.41 2150 21493 all phecode
381.1 Otitis media Sense Organs 0.98 0.933 – 1.03 0.424 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1 0.934 – 1.08 0.94 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 1.04 0.9 – 1.21 0.569 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 0.924 0.786 – 1.09 0.335 171 1709 all phecode
381.9 Otorrhea Sense Organs 0.977 0.864 – 1.1 0.706 281 2807 all phecode
382 Otalgia Sense Organs 0.953 0.847 – 1.07 0.428 308 3084 all phecode
383 Otosclerosis Sense Organs 1.04 0.922 – 1.17 0.533 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 1 0.944 – 1.06 0.987 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.02 0.958 – 1.09 0.514 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.984 0.913 – 1.06 0.664 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 0.997 0.917 – 1.09 0.954 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.979 0.858 – 1.12 0.75 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.02 0.97 – 1.07 0.45 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 1.02 0.935 – 1.11 0.666 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 1.02 0.916 – 1.13 0.72 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 0.997 0.926 – 1.07 0.93 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.01 0.976 – 1.04 0.707 4582 45806 all phecode
388 Other disorders of ear Sense Organs 1.1 0.95 – 1.27 0.207 202 2017 all phecode
389 Hearing loss Sense Organs 0.993 0.962 – 1.03 0.681 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.979 0.889 – 1.08 0.66 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 1.03 0.934 – 1.13 0.572 450 4497 all phecode
389.4 Tinnitus Sense Organs 1.08 0.981 – 1.18 0.121 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.02 0.989 – 1.05 0.218 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 1.01 0.973 – 1.05 0.572 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 1.03 0.972 – 1.09 0.31 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 0.983 0.923 – 1.05 0.596 1058 10566 all phecode
395 Heart valve disorders Circulatory System 1.03 0.995 – 1.06 0.101 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.01 0.976 – 1.05 0.459 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.06 0.936 – 1.2 0.359 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 0.972 0.802 – 1.18 0.777 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.933 0.758 – 1.15 0.517 97 970 all phecode
395.6 Heart valve replaced Circulatory System 1.07 1.01 – 1.13 0.0184 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 1.02 0.951 – 1.08 0.651 1048 10468 all phecode
401 Hypertension Circulatory System 0.99 0.982 – 0.999 0.0237 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 0.991 0.982 – 0.999 0.028 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 0.891 0.849 – 0.934 2.03e-06 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 1.05 0.944 – 1.17 0.358 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.857 0.813 – 0.904 1.2e-08 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 0.879 0.742 – 1.04 0.135 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 0.986 0.934 – 1.04 0.595 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 1.01 0.995 – 1.02 0.237 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.02 0.995 – 1.05 0.104 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 1.01 0.995 – 1.03 0.157 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 1.01 0.995 – 1.03 0.192 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.01 0.994 – 1.02 0.219 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.991 0.916 – 1.07 0.83 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.02 1 – 1.03 0.0473 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.99 0.933 – 1.05 0.736 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 1.03 0.98 – 1.08 0.266 1823 18228 all phecode
414.2 ASCVD Circulatory System 1.09 0.861 – 1.39 0.459 72 719 all phecode
415 Pulmonary heart disease Circulatory System 0.982 0.952 – 1.01 0.245 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.931 0.737 – 1.18 0.548 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.02 0.937 – 1.11 0.641 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 0.994 0.9 – 1.1 0.907 448 4475 all phecode
416 Cardiomegaly Circulatory System 1.02 0.978 – 1.06 0.382 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 1.01 0.997 – 1.02 0.132 28599 270106 all phecode
418.1 Precordial pain Circulatory System 0.992 0.958 – 1.03 0.651 3551 35541 all phecode
420 Carditis Circulatory System 0.982 0.938 – 1.03 0.417 2106 21053 all phecode
420.1 Myocarditis Circulatory System 0.978 0.818 – 1.17 0.803 127 1267 all phecode
420.2 Pericarditis Circulatory System 0.986 0.933 – 1.04 0.634 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 1.04 0.907 – 1.19 0.566 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 0.96 0.79 – 1.17 0.683 113 1129 all phecode
420.3 Endocarditis Circulatory System 0.998 0.924 – 1.08 0.969 719 7194 all phecode
425 Cardiomyopathy Circulatory System 1.1 1.03 – 1.16 0.00206 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.08 1.02 – 1.15 0.00806 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.2 1.01 – 1.42 0.0391 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.1 0.934 – 1.29 0.26 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 1.54 1.18 – 2.01 0.00127 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 1.03 1 – 1.05 0.0379 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.03 0.986 – 1.08 0.182 2114 21162 all phecode
426.21 First degree AV block Circulatory System 1.05 0.982 – 1.12 0.155 986 9867 all phecode
426.23 Second degree AV block Circulatory System 1.04 0.946 – 1.15 0.403 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 1 0.918 – 1.09 0.998 587 5868 all phecode
426.25 Other heart block Circulatory System 0.907 0.762 – 1.08 0.267 131 1318 all phecode
426.3 Bundle branch block Circulatory System 1.03 0.996 – 1.07 0.0788 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 1 0.95 – 1.06 0.956 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 1.05 1 – 1.11 0.0372 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.1 0.96 – 1.25 0.173 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.11 0.854 – 1.44 0.44 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.06 1.02 – 1.1 0.00612 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.06 1.02 – 1.11 0.00741 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 1.01 0.994 – 1.02 0.283 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1 0.965 – 1.04 0.956 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.998 0.956 – 1.04 0.923 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.03 0.963 – 1.1 0.383 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.01 0.993 – 1.03 0.231 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.01 0.971 – 1.04 0.739 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.01 0.956 – 1.08 0.644 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.07 0.955 – 1.19 0.248 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 1.01 0.946 – 1.08 0.775 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.994 0.931 – 1.06 0.869 952 9541 all phecode
427.6 Premature beats Circulatory System 1.07 0.976 – 1.16 0.159 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 1 0.828 – 1.22 0.97 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 1.01 0.962 – 1.05 0.81 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.07 0.964 – 1.18 0.204 402 4029 all phecode
427.9 Palpitations Circulatory System 1 0.969 – 1.04 0.88 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.05 1.02 – 1.07 0.00162 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.03 0.988 – 1.08 0.151 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 1.05 1.02 – 1.08 0.00203 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 0.982 0.91 – 1.06 0.647 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 1.06 0.834 – 1.35 0.626 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.977 0.894 – 1.07 0.61 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.01 0.875 – 1.17 0.856 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 0.996 0.95 – 1.04 0.872 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.981 0.913 – 1.05 0.609 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 0.979 0.909 – 1.05 0.578 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 1.08 0.949 – 1.22 0.254 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 1.01 0.987 – 1.03 0.419 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.02 0.961 – 1.08 0.507 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.05 0.911 – 1.2 0.528 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.01 0.976 – 1.04 0.644 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.03 0.983 – 1.09 0.19 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 0.997 0.959 – 1.04 0.859 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 0.979 0.937 – 1.02 0.36 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 1 0.902 – 1.11 0.977 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.07 1.01 – 1.13 0.0292 1279 12783 all phecode
440 Atherosclerosis Circulatory System 0.944 0.893 – 0.997 0.0403 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.947 0.781 – 1.15 0.576 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.956 0.889 – 1.03 0.22 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 0.904 0.8 – 1.02 0.106 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 0.996 0.915 – 1.08 0.918 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.03 0.91 – 1.16 0.663 283 2827 all phecode
442 Other aneurysm Circulatory System 0.996 0.95 – 1.04 0.881 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 1 0.949 – 1.06 0.945 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.994 0.929 – 1.06 0.852 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 0.929 0.761 – 1.13 0.469 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.07 0.908 – 1.25 0.436 169 1696 all phecode
442.4 Arterial dissection Circulatory System 0.893 0.681 – 1.17 0.416 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 0.866 0.749 – 1 0.0531 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 0.963 0.932 – 0.995 0.0235 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 1 0.943 – 1.07 0.938 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.964 0.869 – 1.07 0.493 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 0.956 0.924 – 0.989 0.00869 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.939 0.902 – 0.978 0.00229 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 0.961 0.898 – 1.03 0.247 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.904 0.828 – 0.986 0.0224 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1 0.932 – 1.08 0.964 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 0.935 0.806 – 1.08 0.372 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 1.05 0.945 – 1.16 0.367 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 0.99 0.868 – 1.13 0.884 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 0.965 0.912 – 1.02 0.21 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 0.974 0.909 – 1.04 0.459 868 8712 all phecode
448 Disease of capillaries Circulatory System 1.05 0.882 – 1.24 0.603 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.989 0.914 – 1.07 0.777 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.975 0.944 – 1.01 0.127 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.967 0.934 – 1 0.0495 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.981 0.9 – 1.07 0.673 564 5645 all phecode
454 Varicose veins Circulatory System 1.01 0.993 – 1.03 0.197 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1.02 0.999 – 1.04 0.0621 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.03 0.951 – 1.12 0.453 624 6325 all phecode
455 Hemorrhoids Circulatory System 1 0.991 – 1.02 0.49 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.922 0.793 – 1.07 0.288 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.992 0.803 – 1.23 0.944 97 967 all phecode
458 Hypotension Circulatory System 0.992 0.965 – 1.02 0.553 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 0.959 0.907 – 1.01 0.141 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.04 0.907 – 1.19 0.588 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 0.989 0.955 – 1.02 0.518 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 0.988 0.972 – 1 0.154 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 0.943 0.795 – 1.12 0.502 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 0.99 0.974 – 1.01 0.237 16103 159422 all phecode
464 Acute sinusitis Respiratory 0.916 0.788 – 1.07 0.257 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.01 0.969 – 1.06 0.603 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 0.997 0.929 – 1.07 0.94 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.01 0.858 – 1.18 0.946 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.01 0.978 – 1.04 0.579 4654 46553 all phecode
471 Nasal polyps Respiratory 1.03 0.99 – 1.06 0.152 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.981 0.918 – 1.05 0.571 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 0.971 0.932 – 1.01 0.16 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 1.03 0.837 – 1.26 0.81 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.901 0.794 – 1.02 0.107 264 2647 all phecode
473.4 Voice disturbance Respiratory 0.975 0.915 – 1.04 0.428 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 0.935 0.89 – 0.982 0.00724 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 0.907 0.83 – 0.991 0.0314 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.942 0.886 – 1 0.0575 1122 11199 all phecode
475 Chronic sinusitis Respiratory 1.01 0.965 – 1.05 0.783 2589 25882 all phecode
476 Allergic rhinitis Respiratory 1.03 0.963 – 1.09 0.428 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.01 0.969 – 1.05 0.647 2447 24452 all phecode
478 Throat pain Respiratory 0.966 0.867 – 1.07 0.521 377 3789 all phecode
479 Other upper respiratory disease Respiratory 1.02 0.983 – 1.05 0.339 4074 40737 all phecode
480 Pneumonia Respiratory 0.998 0.978 – 1.02 0.85 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 0.995 0.97 – 1.02 0.681 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 0.99 0.964 – 1.02 0.477 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.04 0.846 – 1.28 0.711 93 929 all phecode
480.2 Viral pneumonia Respiratory 1.2 0.935 – 1.55 0.15 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.03 0.845 – 1.26 0.75 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.993 0.923 – 1.07 0.842 794 7951 all phecode
481 Influenza Respiratory 0.969 0.864 – 1.09 0.594 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.989 0.855 – 1.15 0.886 193 1930 all phecode
495 Asthma Respiratory 1 0.992 – 1.02 0.484 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 1.08 0.948 – 1.23 0.25 250 2510 all phecode
496 Chronic airway obstruction Respiratory 0.996 0.976 – 1.02 0.664 10424 101546 all phecode
496.1 Emphysema Respiratory 0.975 0.929 – 1.02 0.32 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 0.972 0.936 – 1.01 0.141 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 0.983 0.945 – 1.02 0.397 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 1.01 0.966 – 1.06 0.598 1885 18859 all phecode
497 Bronchitis Respiratory 0.927 0.855 – 1 0.0642 626 6267 all phecode
500 Lung disease due to external agents Respiratory 0.893 0.808 – 0.988 0.028 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.899 0.715 – 1.13 0.365 79 784 all phecode
500.2 Pneumoconiosis Respiratory 0.836 0.734 – 0.952 0.0069 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1 0.926 – 1.09 0.941 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.951 0.889 – 1.02 0.148 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.05 0.959 – 1.15 0.289 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.872 0.777 – 0.978 0.0189 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 0.807 0.614 – 1.06 0.123 61 610 all phecode
506 Empyema and pneumothorax Respiratory 1.02 0.963 – 1.09 0.451 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 1 0.975 – 1.03 0.964 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.97 0.927 – 1.02 0.199 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.996 0.956 – 1.04 0.829 2599 26031 all phecode
509.1 Respiratory failure Respiratory 0.995 0.951 – 1.04 0.84 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 1 0.953 – 1.05 0.991 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 1 0.848 – 1.18 0.984 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.988 0.889 – 1.1 0.823 386 3863 all phecode
510 Other diseases of lung Respiratory 0.988 0.917 – 1.07 0.758 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 0.992 0.971 – 1.01 0.484 9031 90349 all phecode
512.1 Wheezing Respiratory 0.988 0.858 – 1.14 0.861 220 2196 all phecode
512.2 Painful respiration Respiratory 1.05 0.908 – 1.21 0.533 207 2075 all phecode
512.7 Shortness of breath Respiratory 1 0.974 – 1.03 0.954 5842 58498 all phecode
512.8 Cough Respiratory 0.966 0.929 – 1 0.077 2866 28642 all phecode
512.9 Other dyspnea Respiratory 1.02 0.952 – 1.09 0.572 914 9124 all phecode
513 Respiratory abnormalities Respiratory 1.02 0.942 – 1.11 0.585 611 6112 all phecode
513.3 Hypoventilation Respiratory 0.983 0.792 – 1.22 0.876 83 830 all phecode
513.4 Hyperventilation Respiratory 1.03 0.91 – 1.16 0.65 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 1.06 0.898 – 1.26 0.482 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 0.989 0.949 – 1.03 0.611 2465 24673 all phecode
516 Abnormal sputum Respiratory 1.02 0.972 – 1.06 0.478 2132 21335 all phecode
516.1 Hemoptysis Respiratory 1.01 0.969 – 1.06 0.541 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.995 0.974 – 1.02 0.669 9366 93681 all phecode
519.2 Respiratory complications Respiratory 0.947 0.844 – 1.06 0.35 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.993 0.972 – 1.02 0.556 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.99 0.879 – 1.12 0.872 303 3049 all phecode
520 Disorders of tooth development Digestive 0.968 0.924 – 1.01 0.165 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.18 0.892 – 1.56 0.247 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 0.966 0.926 – 1.01 0.115 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 0.98 0.944 – 1.02 0.289 3016 30245 all phecode
521.1 Dental caries Digestive 0.979 0.943 – 1.02 0.261 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.03 0.979 – 1.08 0.264 1774 17750 all phecode
522.5 Periapical abscess Digestive 1.02 0.964 – 1.09 0.438 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 0.98 0.932 – 1.03 0.418 1681 16812 all phecode
523.1 Gingivitis Digestive 1.18 0.974 – 1.42 0.0918 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 0.979 0.922 – 1.04 0.501 1165 11650 all phecode
523.31 Acute periodontitis Digestive 0.971 0.897 – 1.05 0.469 666 6667 all phecode
523.32 Chronic periodontitis Digestive 0.969 0.888 – 1.06 0.482 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.985 0.878 – 1.1 0.794 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.999 0.886 – 1.12 0.98 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.02 0.983 – 1.06 0.267 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.03 0.819 – 1.3 0.787 72 720 all phecode
526 Diseases of the jaws Digestive 1.05 0.977 – 1.12 0.195 928 9279 all phecode
526.1 Cysts of the jaws Digestive 1.11 0.988 – 1.24 0.0806 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.911 0.702 – 1.18 0.486 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.02 0.892 – 1.16 0.798 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.02 0.893 – 1.16 0.773 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 1.08 0.884 – 1.31 0.463 110 1098 all phecode
526.9 Jaw disease NOS Digestive 1.06 0.931 – 1.22 0.358 233 2329 all phecode
527 Diseases of the salivary glands Digestive 0.993 0.917 – 1.08 0.858 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.1 0.875 – 1.39 0.413 84 838 all phecode
527.2 Sialoadenitis Digestive 0.967 0.868 – 1.08 0.549 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 1.11 0.855 – 1.44 0.435 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.03 0.856 – 1.24 0.75 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.01 0.973 – 1.04 0.744 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 1.02 0.923 – 1.12 0.757 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.02 0.918 – 1.13 0.747 389 3884 all phecode
528.12 Oral aphthae Digestive 1.11 0.885 – 1.4 0.358 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.903 0.776 – 1.05 0.187 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 0.936 0.78 – 1.12 0.474 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 0.873 0.716 – 1.06 0.179 94 940 all phecode
528.5 Diseases of lips Digestive 1.11 1.03 – 1.2 0.00714 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.01 0.9 – 1.13 0.874 308 3079 all phecode
528.7 Sialolithiasis Digestive 0.981 0.874 – 1.1 0.741 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 1.02 0.959 – 1.08 0.59 1232 12312 all phecode
529.1 Glossitis Digestive 1.07 0.949 – 1.2 0.282 299 2986 all phecode
530 Diseases of esophagus Digestive 0.996 0.985 – 1.01 0.531 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.996 0.984 – 1.01 0.454 31253 272429 all phecode
530.11 GERD Digestive 0.993 0.98 – 1.01 0.349 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 1 0.972 – 1.03 0.985 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 0.983 0.963 – 1 0.0967 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.989 0.94 – 1.04 0.669 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 0.971 0.926 – 1.02 0.229 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 0.964 0.887 – 1.05 0.379 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.04 0.883 – 1.22 0.662 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.03 0.916 – 1.15 0.665 341 3416 all phecode
530.9 Heartburn Digestive 0.971 0.928 – 1.02 0.199 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.02 0.991 – 1.04 0.203 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1 0.922 – 1.09 0.987 637 6374 all phecode
531.2 Gastric ulcer Digestive 1.02 0.985 – 1.05 0.307 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 1.02 0.978 – 1.05 0.431 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.04 0.945 – 1.15 0.402 427 4268 all phecode
532 Dysphagia Digestive 0.989 0.964 – 1.01 0.399 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 1 0.989 – 1.01 0.797 28078 261548 all phecode
535.1 Acute gastritis Digestive 1.02 0.964 – 1.09 0.453 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 0.969 0.87 – 1.08 0.564 370 3687 all phecode
535.6 Duodenitis Digestive 0.989 0.966 – 1.01 0.351 7592 75928 all phecode
535.8 Other specified gastritis Digestive 1.01 0.989 – 1.04 0.315 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.895 0.739 – 1.08 0.256 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.01 0.889 – 1.15 0.871 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 0.986 0.951 – 1.02 0.435 3391 33907 all phecode
540 Appendiceal conditions Digestive 0.996 0.96 – 1.03 0.852 3088 30890 all phecode
540.1 Appendicitis Digestive 1 0.963 – 1.04 0.965 2895 28963 all phecode
540.11 Acute appendicitis Digestive 0.99 0.951 – 1.03 0.625 2601 26019 all phecode
550 Abdominal hernia Digestive 1.02 1.01 – 1.03 0.00138 45429 282640 all phecode
550.1 Inguinal hernia Digestive 1.03 1.02 – 1.05 0.000153 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 1.01 0.995 – 1.02 0.221 26494 238953 all phecode
550.3 Femoral hernia Digestive 1.01 0.932 – 1.1 0.785 651 6504 all phecode
550.4 Umbilical hernia Digestive 1.02 0.99 – 1.06 0.16 3705 37072 all phecode
550.5 Ventral hernia Digestive 0.992 0.957 – 1.03 0.657 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.03 1 – 1.06 0.0454 4444 44442 all phecode
555.1 Regional enteritis Digestive 1.02 0.974 – 1.08 0.359 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 1.03 0.99 – 1.06 0.162 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.03 0.942 – 1.12 0.528 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 1.04 0.976 – 1.11 0.218 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 1.07 0.991 – 1.16 0.0834 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.917 0.813 – 1.03 0.16 299 2987 all phecode
557.1 Celiac disease Digestive 0.853 0.813 – 0.896 1.18e-10 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 0.996 0.979 – 1.01 0.624 15492 155105 all phecode
559 Ileostomy status Digestive 0.997 0.947 – 1.05 0.901 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.01 0.975 – 1.04 0.636 3936 39337 all phecode
560.1 Paralytic ileus Digestive 1.02 0.928 – 1.11 0.742 523 5231 all phecode
560.2 Impaction of intestine Digestive 1.06 0.937 – 1.2 0.346 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.01 0.94 – 1.08 0.793 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 1 0.969 – 1.04 0.817 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 0.995 0.979 – 1.01 0.534 15772 157686 all phecode
561.1 Diarrhea Digestive 0.899 0.818 – 0.988 0.0277 466 4653 all phecode
561.2 Flatulence Digestive 1.03 0.975 – 1.08 0.326 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 1 0.988 – 1.01 0.895 26714 211692 all phecode
562.1 Diverticulosis Digestive 1 0.988 – 1.01 0.878 26672 211642 all phecode
563 Constipation Digestive 0.99 0.97 – 1.01 0.349 10314 103140 all phecode
564 Functional digestive disorders Digestive 1.01 0.992 – 1.02 0.427 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 0.992 0.964 – 1.02 0.553 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.01 0.957 – 1.06 0.794 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 1.01 0.991 – 1.02 0.363 15186 151648 all phecode
565 Anal and rectal conditions Digestive 1 0.984 – 1.02 0.937 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 1 0.977 – 1.02 0.969 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 0.972 0.91 – 1.04 0.411 929 9293 all phecode
568 Other disorders of peritoneum Digestive 1.03 0.992 – 1.07 0.124 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.02 0.986 – 1.06 0.232 3101 30987 all phecode
569 Other disorders of intestine Digestive 0.997 0.966 – 1.03 0.849 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.964 0.814 – 1.14 0.671 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 1.01 0.916 – 1.1 0.904 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 0.981 0.944 – 1.02 0.318 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 0.963 0.916 – 1.01 0.141 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.802 0.667 – 0.964 0.0186 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 0.993 0.874 – 1.13 0.914 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.981 0.918 – 1.05 0.564 976 9804 all phecode
571.81 Portal hypertension Digestive 0.996 0.911 – 1.09 0.931 528 5285 all phecode
572 Ascites (non malignant) Digestive 1.01 0.962 – 1.07 0.595 1544 15454 all phecode
573 Other disorders of liver Digestive 0.999 0.947 – 1.05 0.968 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 1.11 0.909 – 1.36 0.304 96 960 all phecode
573.3 Hepatomegaly Digestive 1.02 0.909 – 1.15 0.712 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 0.966 0.901 – 1.03 0.322 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 0.985 0.951 – 1.02 0.412 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 0.941 0.818 – 1.08 0.389 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.01 0.992 – 1.03 0.308 15607 156123 all phecode
574.1 Cholelithiasis Digestive 1 0.986 – 1.02 0.708 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.01 0.955 – 1.06 0.791 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1 0.977 – 1.03 0.734 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 1.01 0.968 – 1.05 0.707 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.04 0.996 – 1.08 0.0766 2748 27523 all phecode
575 Other biliary tract disease Digestive 1.03 0.992 – 1.06 0.142 3867 38724 all phecode
575.1 Cholangitis Digestive 0.97 0.885 – 1.06 0.522 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 1.03 0.951 – 1.11 0.513 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.975 0.886 – 1.07 0.597 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 1.04 0.98 – 1.09 0.22 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 1.05 0.981 – 1.12 0.169 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.06 0.952 – 1.18 0.288 348 3488 all phecode
577 Diseases of pancreas Digestive 0.98 0.942 – 1.02 0.332 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 0.965 0.922 – 1.01 0.136 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 0.966 0.882 – 1.06 0.462 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.929 0.833 – 1.04 0.187 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.993 – 1.02 0.284 20626 206278 all phecode
578.1 Hematemesis Digestive 0.999 0.953 – 1.05 0.965 1958 19564 all phecode
578.2 Blood in stool Digestive 1.03 0.987 – 1.07 0.192 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.01 0.99 – 1.03 0.409 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.03 0.997 – 1.06 0.0775 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.977 0.926 – 1.03 0.377 1548 15498 all phecode
579.2 Splenomegaly Digestive 0.929 0.839 – 1.03 0.157 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.04 0.991 – 1.1 0.106 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.863 0.819 – 0.91 4.2e-08 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 0.833 0.782 – 0.888 1.95e-08 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.956 0.756 – 1.21 0.71 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.931 0.776 – 1.12 0.443 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.809 0.755 – 0.868 2.46e-09 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.972 0.884 – 1.07 0.551 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.875 0.767 – 0.998 0.046 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.868 0.762 – 0.989 0.0335 253 2529 all phecode
585 Renal failure Genitourinary 0.909 0.886 – 0.931 3.72e-14 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 0.939 0.911 – 0.969 6.92e-05 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 0.903 0.855 – 0.953 0.000241 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.858 0.824 – 0.893 8.26e-14 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 0.937 0.853 – 1.03 0.176 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1 0.966 – 1.04 0.938 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.09 0.945 – 1.26 0.238 208 2089 all phecode
586.11 Small kidney Genitourinary 1.04 0.89 – 1.21 0.625 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.03 0.969 – 1.09 0.367 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.07 0.852 – 1.33 0.575 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.03 0.958 – 1.1 0.475 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 0.967 0.868 – 1.08 0.539 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.17 0.951 – 1.44 0.137 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 0.883 0.728 – 1.07 0.208 116 1158 all phecode
590 Pyelonephritis Genitourinary 1.02 0.964 – 1.08 0.477 1328 13285 all phecode
591 Urinary tract infection Genitourinary 1 0.982 – 1.02 0.988 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 0.985 0.948 – 1.02 0.427 2966 29661 all phecode
592.1 Cystitis Genitourinary 0.986 0.95 – 1.02 0.483 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 1.06 0.89 – 1.27 0.504 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 0.964 0.899 – 1.03 0.306 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.88 0.774 – 1 0.0505 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.06 0.9 – 1.24 0.499 165 1662 all phecode
593 Hematuria Genitourinary 1.02 1.01 – 1.04 0.00334 16068 160204 all phecode
594 Urinary calculus Genitourinary 1.1 1.08 – 1.13 6.72e-14 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 1.14 1.1 – 1.18 8.02e-12 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.08 1 – 1.16 0.0441 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 1.11 1.06 – 1.15 3.53e-06 2401 24024 all phecode
594.8 Renal colic Genitourinary 1.08 1.03 – 1.13 0.00139 2050 20500 all phecode
595 Hydronephrosis Genitourinary 1.03 0.985 – 1.08 0.186 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 0.999 0.979 – 1.02 0.956 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 1.02 0.976 – 1.07 0.346 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 1.02 0.973 – 1.08 0.361 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.02 0.99 – 1.06 0.167 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.03 0.992 – 1.07 0.128 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 1.19 0.943 – 1.49 0.144 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 0.996 0.962 – 1.03 0.814 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.01 0.903 – 1.14 0.812 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.998 – 1.03 0.0972 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 0.99 0.844 – 1.16 0.898 166 1670 all phecode
599.2 Retention of urine Genitourinary 1.01 0.983 – 1.03 0.529 6718 67168 all phecode
599.3 Dysuria Genitourinary 0.98 0.924 – 1.04 0.501 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 1.01 0.987 – 1.03 0.444 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.02 0.988 – 1.05 0.228 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 0.986 0.81 – 1.2 0.885 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.21 0.931 – 1.57 0.154 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 0.997 0.951 – 1.05 0.903 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 0.999 0.979 – 1.02 0.919 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.999 0.955 – 1.05 0.974 2081 20818 all phecode
601.1 Prostatitis Genitourinary 1 0.951 – 1.06 0.929 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 0.982 0.858 – 1.12 0.798 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 1.01 0.941 – 1.08 0.839 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.12 0.853 – 1.46 0.425 59 588 all phecode
601.4 Balanoposthitis Genitourinary 1.04 0.922 – 1.18 0.507 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.936 0.831 – 1.05 0.27 303 3019 all phecode
602 Other disorders of prostate Genitourinary 1.02 0.966 – 1.08 0.454 1341 13408 all phecode
603 Other disorders of testis Genitourinary 0.945 0.904 – 0.988 0.0123 2150 21512 all phecode
603.1 Hydrocele Genitourinary 0.915 0.865 – 0.968 0.00209 1339 13402 all phecode
604 Disorders of penis Genitourinary 0.996 0.961 – 1.03 0.818 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.979 0.941 – 1.02 0.288 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 0.979 0.867 – 1.11 0.733 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 0.983 0.946 – 1.02 0.399 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.06 0.925 – 1.22 0.388 214 2138 all phecode
609.1 Infertility, male Genitourinary 1.03 0.79 – 1.33 0.845 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 1.08 0.925 – 1.27 0.321 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 0.989 0.949 – 1.03 0.615 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 0.974 0.909 – 1.04 0.444 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.01 0.896 – 1.13 0.911 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 1.01 0.897 – 1.14 0.88 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.994 0.94 – 1.05 0.825 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.01 0.935 – 1.09 0.792 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.985 0.934 – 1.04 0.563 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 0.801 0.602 – 1.07 0.128 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 0.989 0.938 – 1.04 0.686 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.02 0.95 – 1.09 0.608 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.02 0.953 – 1.1 0.526 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 1.04 0.813 – 1.33 0.748 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 1.02 0.97 – 1.07 0.438 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 0.987 0.914 – 1.07 0.735 720 7210 all phecode
613.5 Mastodynia Genitourinary 0.8 0.63 – 1.02 0.067 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 1.04 0.964 – 1.13 0.299 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 1.13 1.01 – 1.27 0.037 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 0.978 0.847 – 1.13 0.756 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.03 0.999 – 1.05 0.061 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.03 0.99 – 1.07 0.145 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.02 0.946 – 1.09 0.657 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.829 0.642 – 1.07 0.151 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.03 0.931 – 1.14 0.556 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.967 0.867 – 1.08 0.55 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.973 0.857 – 1.1 0.672 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.03 0.985 – 1.07 0.228 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.04 0.984 – 1.1 0.166 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.89 0.806 – 0.983 0.0219 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.08 1 – 1.17 0.0388 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.05 0.928 – 1.19 0.426 274 2737 all phecode
615 Endometriosis Genitourinary 0.979 0.948 – 1.01 0.212 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.02 0.909 – 1.15 0.704 304 3037 all phecode
618 Genital prolapse Genitourinary 1.04 1.02 – 1.06 4.9e-05 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1.04 1.01 – 1.06 0.00229 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.04 1.01 – 1.07 0.00635 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.948 0.865 – 1.04 0.257 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.09 1 – 1.18 0.0398 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 1.01 0.987 – 1.03 0.411 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.03 0.957 – 1.11 0.413 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1.01 0.975 – 1.05 0.554 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.988 0.95 – 1.03 0.527 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.05 1 – 1.11 0.0387 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.972 0.919 – 1.03 0.325 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 1.18 0.931 – 1.49 0.173 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 0.984 0.925 – 1.05 0.619 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 1 0.98 – 1.02 0.989 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.986 0.963 – 1.01 0.231 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 1 0.967 – 1.04 0.925 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.03 0.971 – 1.09 0.337 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 0.976 0.908 – 1.05 0.513 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.994 0.87 – 1.13 0.925 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 1.02 0.924 – 1.12 0.708 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 1 0.978 – 1.03 0.724 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.957 0.921 – 0.995 0.026 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 0.956 0.9 – 1.02 0.143 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.993 0.977 – 1.01 0.406 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.993 0.976 – 1.01 0.461 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.808 0.664 – 0.984 0.0338 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 0.989 0.968 – 1.01 0.3 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 0.977 0.932 – 1.02 0.317 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 1 0.968 – 1.04 0.946 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 0.942 0.897 – 0.99 0.0175 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.989 0.839 – 1.17 0.899 159 1587 all phecode
626.8 Infertility, female Genitourinary 1.03 0.976 – 1.09 0.268 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.996 0.976 – 1.02 0.667 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 0.991 0.969 – 1.01 0.391 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 0.86 0.74 – 1 0.05 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.03 0.967 – 1.09 0.374 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 1.02 0.908 – 1.15 0.733 310 3097 all phecode
628 Ovarian cyst Genitourinary 0.984 0.955 – 1.01 0.303 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.02 0.987 – 1.05 0.266 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.973 0.915 – 1.03 0.378 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.04 0.925 – 1.16 0.534 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.993 0.948 – 1.04 0.773 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1.01 0.94 – 1.08 0.804 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.976 0.921 – 1.03 0.402 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.987 0.945 – 1.03 0.548 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.935 0.861 – 1.02 0.114 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.986 0.927 – 1.05 0.667 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 0.975 0.765 – 1.24 0.84 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.06 0.996 – 1.13 0.0678 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.11 0.99 – 1.25 0.0725 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.1 0.954 – 1.27 0.188 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.96 0.81 – 1.14 0.637 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.04 0.986 – 1.11 0.14 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.971 0.929 – 1.01 0.185 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1 0.787 – 1.28 0.972 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.979 0.865 – 1.11 0.739 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.987 0.815 – 1.2 0.894 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.03 0.887 – 1.19 0.732 193 1922 all phecode
650 Normal delivery Pregnancy Complications 1 0.954 – 1.05 0.994 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 1.01 0.905 – 1.13 0.845 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.98 0.932 – 1.03 0.426 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.04 0.988 – 1.1 0.121 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 0.844 0.662 – 1.08 0.17 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1 0.972 – 1.04 0.808 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.05 0.859 – 1.27 0.659 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 1 0.957 – 1.04 0.997 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 1.02 0.931 – 1.11 0.714 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.987 0.958 – 1.02 0.376 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.03 0.987 – 1.07 0.189 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.07 0.909 – 1.26 0.424 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.13 0.998 – 1.28 0.0531 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.09 0.842 – 1.42 0.506 63 624 all phecode
679 Complications of in utero procedures Dermatologic 0.815 0.619 – 1.07 0.146 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 0.994 0.97 – 1.02 0.65 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.05 0.965 – 1.15 0.247 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.04 0.951 – 1.14 0.381 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.988 0.96 – 1.02 0.381 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.988 0.96 – 1.02 0.379 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.985 0.958 – 1.01 0.282 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.08 0.992 – 1.18 0.0771 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 0.988 0.934 – 1.04 0.662 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.1 1.05 – 1.15 2.17e-05 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 1.07 0.979 – 1.16 0.141 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 0.975 0.876 – 1.09 0.648 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1.04 0.949 – 1.13 0.426 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.96 0.919 – 1 0.0765 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 0.985 0.871 – 1.11 0.809 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 1.07 0.879 – 1.31 0.483 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 0.998 0.96 – 1.04 0.903 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.02 0.992 – 1.05 0.164 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.958 0.752 – 1.22 0.726 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.937 0.706 – 1.24 0.65 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 0.8 0.662 – 0.966 0.0207 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 1.02 0.955 – 1.09 0.559 986 9854 all phecode
694.1 Vitiligo Dermatologic 1.13 0.868 – 1.47 0.368 60 599 all phecode
694.2 Other dyschromia Dermatologic 1 0.929 – 1.08 0.993 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 1.04 0.866 – 1.26 0.653 117 1170 all phecode
695 Erythematous conditions Dermatologic 1.05 1 – 1.09 0.038 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 1.09 0.899 – 1.32 0.379 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 1.19 0.993 – 1.42 0.0597 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 0.969 0.744 – 1.26 0.817 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.39 1.08 – 1.79 0.00967 73 727 all phecode
695.3 Rosacea Dermatologic 1.13 0.999 – 1.27 0.0511 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.04 0.942 – 1.15 0.427 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.03 0.867 – 1.22 0.752 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.09 0.975 – 1.22 0.132 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 1.01 0.935 – 1.09 0.849 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 0.977 0.858 – 1.11 0.726 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 0.882 0.699 – 1.11 0.292 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.03 0.937 – 1.13 0.535 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 0.991 0.949 – 1.03 0.679 2252 22509 all phecode
696.4 Psoriasis Dermatologic 0.992 0.949 – 1.04 0.706 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 0.988 0.939 – 1.04 0.63 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.01 0.935 – 1.09 0.778 706 7052 all phecode
697 Sarcoidosis Dermatologic 0.953 0.872 – 1.04 0.287 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 1.06 0.981 – 1.14 0.149 782 7814 all phecode
700 Corns and callosities Dermatologic 1 0.885 – 1.13 0.997 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.01 0.984 – 1.05 0.357 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 1.02 0.818 – 1.26 0.886 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.05 1.01 – 1.1 0.0182 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.08 0.842 – 1.39 0.539 61 610 all phecode
701.4 Keloid scar Dermatologic 1.03 0.895 – 1.18 0.704 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 0.996 0.903 – 1.1 0.938 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 0.905 0.745 – 1.1 0.317 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.999 0.971 – 1.03 0.931 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 1.01 0.966 – 1.05 0.76 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 0.99 0.954 – 1.03 0.59 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 1.01 0.903 – 1.12 0.901 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 1.04 0.972 – 1.11 0.271 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 1.04 1.01 – 1.07 0.006 5267 52727 all phecode
704.1 Alopecia Dermatologic 1.25 1.04 – 1.51 0.0165 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.978 0.766 – 1.25 0.855 76 759 all phecode
705 Disorders of sweat glands Dermatologic 1.04 0.909 – 1.2 0.541 228 2287 all phecode
705.3 Hidradenitis Dermatologic 1.01 0.868 – 1.18 0.871 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 1.05 0.964 – 1.14 0.266 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 1.01 0.99 – 1.04 0.29 8317 83195 all phecode
706.1 Acne Dermatologic 1.39 1.11 – 1.76 0.00494 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 1.01 0.985 – 1.03 0.534 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 0.974 0.93 – 1.02 0.261 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 0.986 0.922 – 1.06 0.693 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.94 0.908 – 0.974 0.000591 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 0.932 0.85 – 1.02 0.136 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 0.96 0.822 – 1.12 0.608 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.15 0.91 – 1.46 0.236 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.947 0.91 – 0.985 0.0067 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.02 0.934 – 1.11 0.702 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 1.02 0.936 – 1.12 0.615 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.04 0.896 – 1.21 0.605 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1 0.905 – 1.11 0.944 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 1 0.907 – 1.11 0.952 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 0.971 0.866 – 1.09 0.614 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 0.869 0.685 – 1.1 0.245 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1 0.847 – 1.19 0.974 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.08 0.846 – 1.38 0.533 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.02 0.994 – 1.05 0.123 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.02 0.993 – 1.06 0.124 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.01 0.961 – 1.06 0.668 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.996 0.828 – 1.2 0.964 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.01 0.933 – 1.1 0.78 618 6177 all phecode
716 Other arthropathies Musculoskeletal 1 0.993 – 1.01 0.491 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.04 1 – 1.07 0.0526 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 1 0.987 – 1.02 0.637 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 1 0.991 – 1.01 0.71 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.993 0.933 – 1.06 0.81 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 0.964 0.932 – 0.997 0.0346 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1.01 0.983 – 1.03 0.584 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.01 0.979 – 1.04 0.611 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.01 0.873 – 1.18 0.852 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 0.957 0.856 – 1.07 0.439 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 0.984 0.962 – 1.01 0.14 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.02 0.928 – 1.11 0.726 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.925 0.89 – 0.962 8.56e-05 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 0.802 0.624 – 1.03 0.0846 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.986 0.956 – 1.02 0.378 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 0.995 0.909 – 1.09 0.918 517 5173 all phecode
723.1 Torticollis Musculoskeletal 1.08 0.896 – 1.31 0.416 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.01 0.967 – 1.06 0.611 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.06 0.954 – 1.17 0.287 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 1.08 0.976 – 1.2 0.135 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 0.897 0.694 – 1.16 0.403 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.01 0.957 – 1.06 0.757 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.987 0.97 – 1 0.12 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 0.98 0.96 – 1 0.0628 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 1.02 0.911 – 1.14 0.747 334 3336 all phecode
726.3 Bursitis Musculoskeletal 0.961 0.896 – 1.03 0.275 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.01 0.981 – 1.03 0.677 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.992 0.954 – 1.03 0.698 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 1.01 0.828 – 1.24 0.902 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.01 0.97 – 1.04 0.725 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 0.96 0.881 – 1.04 0.342 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.985 0.881 – 1.1 0.787 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.09 0.919 – 1.3 0.314 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.979 0.946 – 1.01 0.222 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.01 0.915 – 1.12 0.812 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 0.972 0.94 – 1.01 0.0984 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.984 0.951 – 1.02 0.379 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 0.972 0.947 – 0.998 0.0365 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.999 0.936 – 1.07 0.988 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 1.13 0.923 – 1.38 0.239 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.09 0.963 – 1.23 0.172 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.12 0.983 – 1.27 0.0885 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 0.991 0.902 – 1.09 0.855 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.04 0.904 – 1.2 0.565 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.02 0.779 – 1.33 0.893 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.03 0.976 – 1.08 0.32 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 0.976 0.867 – 1.1 0.683 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.07 0.98 – 1.17 0.131 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 0.84 0.7 – 1.01 0.0615 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.954 0.9 – 1.01 0.114 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 1.06 0.881 – 1.27 0.539 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 1 0.982 – 1.02 0.79 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 0.955 0.822 – 1.11 0.544 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 1.02 0.996 – 1.05 0.0955 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 1 0.957 – 1.05 0.903 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 1.01 0.96 – 1.07 0.673 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.997 0.972 – 1.02 0.82 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 1.01 0.96 – 1.06 0.713 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 0.953 0.839 – 1.08 0.454 248 2476 all phecode
737 Curvature of spine Musculoskeletal 0.939 0.883 – 0.999 0.046 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.941 0.883 – 1 0.0619 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.981 0.936 – 1.03 0.431 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.965 0.915 – 1.02 0.189 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 0.957 0.871 – 1.05 0.369 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 1.01 0.996 – 1.02 0.177 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1 0.986 – 1.02 0.852 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.993 0.972 – 1.02 0.549 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1 0.9 – 1.12 0.961 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.01 0.93 – 1.1 0.774 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.01 0.995 – 1.03 0.147 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.01 0.98 – 1.05 0.417 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 1.12 0.907 – 1.37 0.299 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 0.982 0.903 – 1.07 0.662 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 1.08 0.918 – 1.28 0.343 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 1.03 0.977 – 1.09 0.251 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 0.926 0.759 – 1.13 0.448 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 0.818 0.62 – 1.08 0.157 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.983 0.946 – 1.02 0.39 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 0.984 0.879 – 1.1 0.781 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.914 0.74 – 1.13 0.401 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.01 0.917 – 1.1 0.913 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 0.977 0.933 – 1.02 0.336 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.03 1.01 – 1.05 0.0167 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 1.04 1.02 – 1.07 0.00133 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 1.05 1.02 – 1.08 0.000749 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 1.03 0.945 – 1.13 0.472 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 1.06 0.966 – 1.16 0.226 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.937 0.872 – 1.01 0.0774 815 8144 all phecode
745 Pain in joint Musculoskeletal 0.999 0.976 – 1.02 0.931 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.01 0.971 – 1.05 0.619 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.01 0.972 – 1.05 0.576 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.952 0.873 – 1.04 0.272 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.945 0.826 – 1.08 0.416 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.03 0.984 – 1.08 0.193 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.993 0.844 – 1.17 0.928 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.818 0.615 – 1.09 0.168 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.1 0.974 – 1.24 0.125 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.956 0.884 – 1.03 0.261 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.954 0.852 – 1.07 0.412 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.04 0.899 – 1.2 0.592 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.982 0.881 – 1.1 0.747 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.929 0.811 – 1.06 0.288 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.06 0.873 – 1.29 0.555 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.976 0.926 – 1.03 0.372 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.967 0.894 – 1.05 0.395 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.967 0.878 – 1.06 0.487 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.893 0.778 – 1.02 0.106 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.989 0.921 – 1.06 0.751 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.96 0.868 – 1.06 0.428 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.986 0.88 – 1.1 0.803 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.02 0.915 – 1.15 0.675 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 1.08 0.946 – 1.23 0.265 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 1.13 0.982 – 1.31 0.0883 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.857 0.678 – 1.08 0.199 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.934 0.78 – 1.12 0.456 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.828 0.653 – 1.05 0.119 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.07 0.874 – 1.31 0.513 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.04 0.939 – 1.15 0.462 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.07 0.924 – 1.23 0.379 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.996 0.847 – 1.17 0.956 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.01 0.831 – 1.23 0.905 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.02 0.936 – 1.11 0.67 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.1 0.878 – 1.38 0.404 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.989 0.897 – 1.09 0.82 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.02 0.864 – 1.21 0.791 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.11 0.858 – 1.44 0.427 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.984 0.856 – 1.13 0.821 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.948 0.771 – 1.17 0.615 96 959 all phecode
760 Back pain Symptoms 0.972 0.953 – 0.991 0.00488 11126 111353 all phecode
761 Cervicalgia Symptoms 1.03 0.982 – 1.08 0.216 1791 17901 all phecode
764 Sciatica Symptoms 1.01 0.97 – 1.06 0.593 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.956 0.899 – 1.02 0.15 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 0.957 0.88 – 1.04 0.294 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.02 0.954 – 1.1 0.519 870 8687 all phecode
771.1 Swelling of limb Symptoms 0.969 0.94 – 0.999 0.0415 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 0.977 0.901 – 1.06 0.571 659 6581 all phecode
773 Pain in limb Symptoms 0.967 0.942 – 0.993 0.0133 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 0.931 0.794 – 1.09 0.375 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1 0.956 – 1.05 0.916 1870 18715 all phecode
782.3 Edema Symptoms 1.02 0.969 – 1.07 0.461 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 1.13 0.975 – 1.32 0.103 175 1748 all phecode
783 Fever of unknown origin Symptoms 0.991 0.959 – 1.02 0.596 3911 39105 all phecode
785 Abdominal pain Symptoms 1 0.991 – 1.01 0.837 40080 301686 all phecode
788 Syncope and collapse Symptoms 0.99 0.968 – 1.01 0.34 9069 90813 all phecode
789 Nausea and vomiting Symptoms 0.994 0.975 – 1.01 0.54 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 0.997 0.841 – 1.18 0.969 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 1.04 0.823 – 1.31 0.747 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.01 0.98 – 1.03 0.68 6357 63635 all phecode
791 Gangrene Symptoms 1.02 0.937 – 1.12 0.607 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1.13 0.922 – 1.39 0.238 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.02 0.849 – 1.22 0.858 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.03 0.943 – 1.12 0.509 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.912 0.754 – 1.1 0.345 120 1198 all phecode
797 Shock Symptoms 1.07 0.904 – 1.26 0.443 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 1 0.824 – 1.22 0.964 102 1020 all phecode
798 Malaise and fatigue Symptoms 0.965 0.932 – 1 0.0517 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 0.982 0.901 – 1.07 0.677 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 1.03 1 – 1.05 0.0374 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.03 0.983 – 1.08 0.198 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.03 0.879 – 1.21 0.715 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.05 1 – 1.1 0.0332 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 0.967 0.897 – 1.04 0.376 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.01 0.971 – 1.06 0.526 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.03 0.986 – 1.09 0.164 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.971 0.899 – 1.05 0.447 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.999 0.977 – 1.02 0.937 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.01 0.957 – 1.06 0.819 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.988 0.96 – 1.02 0.393 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.993 0.942 – 1.05 0.807 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 1.02 0.987 – 1.06 0.212 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.982 0.929 – 1.04 0.531 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 1.05 0.977 – 1.13 0.181 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.989 0.934 – 1.05 0.714 1300 12998 all phecode
817 Concussion Injuries & Poisonings 0.995 0.874 – 1.13 0.937 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.03 0.945 – 1.13 0.459 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.01 0.973 – 1.05 0.582 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 1.04 0.989 – 1.09 0.124 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 1.02 0.976 – 1.07 0.361 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 1.01 0.99 – 1.02 0.411 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.02 0.935 – 1.12 0.636 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 0.968 0.88 – 1.06 0.5 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.994 0.967 – 1.02 0.702 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.991 0.841 – 1.17 0.91 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.08 0.989 – 1.19 0.0846 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.02 0.97 – 1.07 0.463 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.927 0.874 – 0.982 0.00999 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.02 0.984 – 1.06 0.261 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.01 0.972 – 1.05 0.661 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 0.987 0.773 – 1.26 0.917 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.02 0.988 – 1.06 0.198 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.989 0.874 – 1.12 0.856 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 1.06 0.915 – 1.23 0.439 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.02 0.983 – 1.06 0.266 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.01 0.878 – 1.16 0.909 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 0.841 0.653 – 1.08 0.181 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.02 0.984 – 1.05 0.312 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1 0.764 – 1.31 0.994 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.01 0.813 – 1.25 0.947 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.16 0.99 – 1.36 0.0663 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 1.01 0.916 – 1.11 0.868 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 1.19 1.04 – 1.37 0.0121 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.06 0.906 – 1.24 0.468 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.05 0.891 – 1.23 0.575 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.02 0.964 – 1.08 0.493 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.01 0.975 – 1.04 0.683 4260 42663 all phecode
916 Contusion Injuries & Poisonings 1.03 0.975 – 1.09 0.302 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 1.1 0.945 – 1.28 0.216 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.05 0.949 – 1.17 0.333 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 1.06 0.929 – 1.2 0.406 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.988 0.944 – 1.03 0.59 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.04 0.906 – 1.19 0.596 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.02 0.835 – 1.24 0.867 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.993 0.911 – 1.08 0.881 550 5509 all phecode
947 Urticaria Injuries & Poisonings 0.991 0.89 – 1.1 0.876 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 1.15 1.04 – 1.28 0.00748 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.05 0.95 – 1.16 0.336 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.01 0.893 – 1.15 0.855 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.928 0.847 – 1.02 0.113 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 0.712 0.535 – 0.946 0.0192 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.866 0.687 – 1.09 0.222 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.01 0.992 – 1.02 0.339 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.01 0.989 – 1.02 0.493 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.05 0.949 – 1.16 0.361 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.994 0.927 – 1.07 0.858 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.94 0.845 – 1.05 0.256 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 0.955 0.856 – 1.06 0.402 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.998 0.87 – 1.14 0.975 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.869 0.769 – 0.982 0.0239 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.862 0.762 – 0.974 0.0175 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.998 0.971 – 1.02 0.854 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.994 0.935 – 1.06 0.858 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.08 0.984 – 1.19 0.103 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.956 0.863 – 1.06 0.387 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.1 1.01 – 1.21 0.0346 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.03 0.945 – 1.12 0.499 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.04 0.991 – 1.09 0.118 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.08 0.931 – 1.25 0.309 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.985 0.872 – 1.11 0.808 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.965 0.775 – 1.2 0.75 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 0.98 0.808 – 1.19 0.838 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.03 0.837 – 1.26 0.808 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.879 0.68 – 1.14 0.325 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.08 0.841 – 1.4 0.537 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.07 0.939 – 1.23 0.296 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.03 0.955 – 1.12 0.424 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.05 0.908 – 1.22 0.494 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 0.754 0.58 – 0.98 0.0349 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.09 0.891 – 1.32 0.413 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 1.01 0.833 – 1.23 0.905 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.04 0.837 – 1.29 0.73 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 0.97 0.935 – 1.01 0.109 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.01 0.977 – 1.05 0.467 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 1.01 0.977 – 1.05 0.467 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 0.984 0.961 – 1.01 0.194 7467 77440 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 0.971 0.93 – 1.01 0.179 2298 23863 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.948 0.867 – 1.04 0.245 524 5780 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.02 0.941 – 1.1 0.664 704 7587 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 0.954 0.714 – 1.27 0.749 42 488 exclusion phecode
010 Tuberculosis Infectious Diseases 0.764 0.639 – 0.913 0.0031 136 1473 exclusion phecode
038 Septicemia Infectious Diseases 1.01 0.979 – 1.05 0.43 3492 37166 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 0.988 0.914 – 1.07 0.758 719 7639 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.01 0.912 – 1.12 0.841 411 4444 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 0.997 0.977 – 1.02 0.759 10078 106125 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 0.984 0.944 – 1.02 0.433 2561 27918 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 0.999 0.945 – 1.06 0.964 1391 14570 exclusion phecode
041.4 E. coli Infectious Diseases 0.997 0.955 – 1.04 0.909 2254 23837 exclusion phecode
053 Herpes zoster Infectious Diseases 1.03 0.924 – 1.15 0.582 351 3578 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.926 0.732 – 1.17 0.522 81 834 exclusion phecode
054 Herpes simplex Infectious Diseases 1.03 0.889 – 1.2 0.665 185 1864 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.02 0.933 – 1.12 0.633 505 5347 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.1 0.841 – 1.45 0.479 55 612 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 1.02 0.847 – 1.23 0.82 113 1226 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.02 0.885 – 1.18 0.763 218 2337 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 0.879 0.768 – 1.01 0.0636 226 2396 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 0.9 0.808 – 1 0.0548 365 3750 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.869 0.726 – 1.04 0.128 128 1381 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.843 0.685 – 1.04 0.107 101 1102 exclusion phecode
078 Viral warts & HPV Infectious Diseases 1.02 0.954 – 1.1 0.519 875 8831 exclusion phecode
079 Viral infection Infectious Diseases 0.986 0.945 – 1.03 0.518 2378 24104 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.866 0.66 – 1.13 0.295 61 573 exclusion phecode
080 Postoperative infection Infectious Diseases 1.02 0.982 – 1.05 0.379 3799 39375 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.03 0.981 – 1.08 0.251 2012 21929 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.951 0.724 – 1.25 0.721 59 623 exclusion phecode
1000 Burns Injuries & Poisonings 0.973 0.886 – 1.07 0.566 497 5192 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 0.987 0.926 – 1.05 0.684 1054 10681 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 0.986 0.957 – 1.02 0.366 4676 47977 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.06 0.932 – 1.22 0.354 245 2649 exclusion phecode
1005 Other symptoms Injuries & Poisonings 1.02 0.961 – 1.08 0.526 1216 12644 exclusion phecode
1006 Crushing injury Injuries & Poisonings 1.02 0.893 – 1.16 0.784 237 2351 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 1.03 0.905 – 1.18 0.634 230 2349 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.02 0.951 – 1.09 0.587 894 9187 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 1 0.98 – 1.03 0.78 7438 75915 exclusion phecode
1010 Other tests Injuries & Poisonings 0.976 0.948 – 1 0.0959 5057 52193 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.01 0.983 – 1.03 0.617 7774 80583 exclusion phecode
1012 Late effect Injuries & Poisonings 1.08 0.874 – 1.33 0.489 95 943 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.05 0.928 – 1.19 0.435 271 2826 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.993 0.752 – 1.31 0.961 58 602 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 0.999 0.965 – 1.03 0.952 3575 37074 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1 0.985 – 1.02 0.761 13517 139544 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.919 0.806 – 1.05 0.21 242 2532 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.916 0.803 – 1.05 0.194 237 2473 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.858 0.664 – 1.11 0.243 67 681 exclusion phecode
110.12 Althete's foot Infectious Diseases 0.932 0.777 – 1.12 0.45 122 1273 exclusion phecode
112 Candidiasis Infectious Diseases 0.97 0.924 – 1.02 0.22 1772 18642 exclusion phecode
117 Mycoses Infectious Diseases 1.02 0.888 – 1.16 0.809 226 2401 exclusion phecode
117.4 Aspergillosis Infectious Diseases 0.907 0.76 – 1.08 0.279 135 1452 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.956 0.749 – 1.22 0.717 73 711 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 0.81 0.626 – 1.05 0.11 62 621 exclusion phecode
134 Helminthiases Infectious Diseases 1.11 0.905 – 1.35 0.325 107 1100 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.09 0.876 – 1.36 0.437 90 926 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.986 0.848 – 1.15 0.85 177 1818 exclusion phecode
145 Cancer of mouth Neoplasms 1.05 0.963 – 1.15 0.259 546 5695 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.08 0.953 – 1.22 0.231 274 2766 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 1.08 0.865 – 1.34 0.509 86 928 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.05 0.778 – 1.4 0.768 49 478 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.06 0.975 – 1.16 0.162 552 5733 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.09 0.951 – 1.25 0.215 221 2282 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.08 0.942 – 1.23 0.277 231 2401 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.24 0.917 – 1.67 0.163 52 506 exclusion phecode
150 Cancer of esophagus Neoplasms 0.98 0.907 – 1.06 0.615 681 6837 exclusion phecode
151 Cancer of stomach Neoplasms 0.978 0.893 – 1.07 0.632 504 5090 exclusion phecode
153 Colorectal cancer Neoplasms 1.01 0.975 – 1.04 0.686 4052 40692 exclusion phecode
153.2 Colon cancer Neoplasms 1 0.965 – 1.04 0.873 2763 27523 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.999 0.953 – 1.05 0.97 1900 19330 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.02 0.915 – 1.14 0.698 339 3531 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.02 0.855 – 1.23 0.8 129 1400 exclusion phecode
157 Pancreatic cancer Neoplasms 0.972 0.892 – 1.06 0.525 565 5803 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.03 0.964 – 1.11 0.361 920 9366 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1 0.975 – 1.03 0.774 4871 49299 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.996 0.854 – 1.16 0.96 173 1696 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.962 0.823 – 1.12 0.621 173 1791 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.948 0.805 – 1.12 0.519 165 1636 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.908 0.69 – 1.2 0.493 52 531 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.01 0.973 – 1.06 0.49 2439 24995 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.01 0.968 – 1.06 0.559 1912 19661 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 0.999 0.899 – 1.11 0.98 391 3887 exclusion phecode
170.1 Bone cancer Neoplasms 1.06 0.881 – 1.28 0.519 119 1179 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 0.985 0.873 – 1.11 0.812 295 2937 exclusion phecode
172 Skin cancer Neoplasms 1.01 0.99 – 1.03 0.378 11779 118841 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1 0.961 – 1.05 0.917 2345 23491 exclusion phecode
172.11 Melanomas of skin Neoplasms 1 0.962 – 1.05 0.872 2375 23769 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1.01 0.987 – 1.03 0.469 9594 97052 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 1.01 0.928 – 1.1 0.78 566 5868 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1 0.851 – 1.18 0.968 152 1601 exclusion phecode
174 Breast cancer Neoplasms 1.02 0.999 – 1.04 0.0609 10477 105842 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1.02 0.997 – 1.04 0.089 10299 103976 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.02 0.996 – 1.04 0.107 9700 98142 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.08 0.876 – 1.32 0.479 97 951 exclusion phecode
175 Acquired absence of breast Neoplasms 1.07 1.02 – 1.12 0.00604 1941 20043 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.02 0.975 – 1.07 0.355 1802 18231 exclusion phecode
180.1 Cervical cancer Neoplasms 1.1 0.956 – 1.26 0.189 228 2276 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.01 0.964 – 1.07 0.6 1715 17390 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 1.01 0.949 – 1.08 0.735 1068 10772 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.02 0.963 – 1.09 0.458 1134 11463 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.03 0.953 – 1.1 0.496 795 8016 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.04 0.961 – 1.12 0.355 770 7802 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.01 0.891 – 1.15 0.85 248 2545 exclusion phecode
185 Cancer of prostate Neoplasms 1.02 0.988 – 1.04 0.277 5516 54408 exclusion phecode
187 Cancer of other male genital organs Neoplasms 0.975 0.883 – 1.08 0.611 416 4184 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.932 0.73 – 1.19 0.569 65 658 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.963 0.85 – 1.09 0.552 264 2684 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.04 0.846 – 1.27 0.732 103 1011 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.01 0.973 – 1.04 0.693 3571 37458 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.05 0.98 – 1.13 0.165 861 9629 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.06 0.991 – 1.14 0.0873 826 9274 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.9 0.689 – 1.18 0.439 60 588 exclusion phecode
189.2 Cancer of bladder Neoplasms 0.975 0.933 – 1.02 0.268 2114 21788 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.971 0.926 – 1.02 0.215 1874 19403 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.971 0.802 – 1.18 0.767 119 1293 exclusion phecode
190 Cancer of eye Neoplasms 1.14 0.963 – 1.36 0.127 153 1533 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.04 0.958 – 1.13 0.34 610 6133 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 1.02 0.931 – 1.12 0.679 507 5022 exclusion phecode
191.11 Cancer of brain Neoplasms 1.03 0.935 – 1.13 0.573 470 4660 exclusion phecode
193 Thyroid cancer Neoplasms 1.12 0.994 – 1.26 0.0625 291 2978 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 0.814 0.653 – 1.02 0.0684 79 854 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.01 0.998 – 1.03 0.0882 14705 146303 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.02 0.999 – 1.03 0.057 14099 141059 exclusion phecode
197 Chemotherapy Neoplasms 1.01 0.995 – 1.03 0.187 18220 186146 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.02 0.996 – 1.04 0.0984 8210 83581 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.03 0.998 – 1.06 0.0694 4623 46616 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.989 0.944 – 1.04 0.654 1958 20046 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.02 0.965 – 1.08 0.455 1310 13457 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.01 0.963 – 1.05 0.809 2288 23573 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.973 0.901 – 1.05 0.489 717 7468 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 0.984 0.938 – 1.03 0.516 1869 19118 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.07 0.908 – 1.26 0.419 152 1669 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 0.956 0.901 – 1.01 0.137 1203 12571 exclusion phecode
199.4 Neurofibromatosis Neoplasms 0.765 0.601 – 0.972 0.0284 72 824 exclusion phecode
200 Myeloproliferative disease Neoplasms 1 0.932 – 1.07 1 835 8816 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.03 0.919 – 1.16 0.609 310 3507 exclusion phecode
201 Hodgkin's disease Neoplasms 0.973 0.848 – 1.12 0.695 225 2311 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.974 0.929 – 1.02 0.264 1949 20174 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.961 0.912 – 1.01 0.139 1567 16064 exclusion phecode
202.21 Nodular lymphoma Neoplasms 0.913 0.813 – 1.02 0.122 318 3236 exclusion phecode
202.24 Large cell lymphoma Neoplasms 0.964 0.88 – 1.06 0.428 516 5177 exclusion phecode
204 Leukemia Neoplasms 0.967 0.916 – 1.02 0.218 1444 14828 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 0.978 0.893 – 1.07 0.638 505 5175 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.06 0.775 – 1.45 0.721 46 497 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.966 0.877 – 1.06 0.489 450 4556 exclusion phecode
204.2 Myeloid leukemia Neoplasms 0.979 0.882 – 1.09 0.685 405 4115 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.916 0.809 – 1.04 0.165 286 2933 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.11 0.924 – 1.33 0.268 127 1257 exclusion phecode
204.4 Multiple myeloma Neoplasms 0.913 0.831 – 1 0.0565 475 4980 exclusion phecode
208 Benign neoplasm of colon Neoplasms 0.986 0.971 – 1 0.0773 17373 170297 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.01 0.943 – 1.09 0.721 833 8584 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.01 0.984 – 1.05 0.362 4561 45541 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.972 0.867 – 1.09 0.632 308 3061 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.938 0.826 – 1.06 0.319 273 2793 exclusion phecode
214 Lipoma Neoplasms 1.03 1 – 1.06 0.0253 5554 55333 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.05 1.01 – 1.08 0.00663 4060 40546 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.946 0.886 – 1.01 0.103 968 9648 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.995 0.97 – 1.02 0.683 6641 66839 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.983 0.899 – 1.07 0.699 550 5516 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.971 0.886 – 1.06 0.536 518 5196 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.997 0.974 – 1.02 0.772 8222 83780 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.997 0.974 – 1.02 0.778 8395 85545 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.04 0.92 – 1.17 0.538 285 2970 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 1.03 0.966 – 1.09 0.415 1207 12125 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.926 0.796 – 1.08 0.324 185 1862 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.968 0.82 – 1.14 0.705 145 1482 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.05 0.885 – 1.25 0.562 146 1539 exclusion phecode
224 Benign neoplasm of eye Neoplasms 1.04 0.851 – 1.28 0.691 104 1131 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.16 0.874 – 1.53 0.31 53 588 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.02 0.943 – 1.11 0.606 678 7104 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.02 0.938 – 1.1 0.68 644 6748 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.877 0.657 – 1.17 0.372 50 511 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.905 0.79 – 1.04 0.148 229 2259 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.03 0.954 – 1.12 0.438 706 7425 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.03 0.872 – 1.22 0.72 148 1628 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.07 0.952 – 1.2 0.257 309 3134 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.997 0.875 – 1.14 0.968 256 2741 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.03 0.974 – 1.09 0.309 1386 13970 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.02 0.975 – 1.07 0.38 2070 20663 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.977 0.892 – 1.07 0.619 506 5098 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.04 0.968 – 1.11 0.301 934 9463 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.03 0.933 – 1.15 0.523 405 4019 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.02 0.934 – 1.11 0.678 565 5788 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.978 0.928 – 1.03 0.409 1524 15859 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.97 0.871 – 1.08 0.575 374 3872 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 0.991 0.785 – 1.25 0.941 68 780 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.812 0.668 – 0.987 0.0369 112 1163 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 0.99 0.971 – 1.01 0.271 12430 123360 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.956 0.893 – 1.02 0.201 915 9429 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.932 0.754 – 1.15 0.513 91 861 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.988 0.969 – 1.01 0.205 11869 118095 exclusion phecode
245 Thyroiditis Endocrine/metabolic 1.02 0.893 – 1.17 0.746 236 2414 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.01 0.869 – 1.18 0.862 181 1823 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.03 0.885 – 1.21 0.672 175 1755 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.07 0.957 – 1.19 0.238 343 3388 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.01 0.997 – 1.03 0.106 16560 166135 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1 0.958 – 1.05 0.95 2166 24694 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.02 0.875 – 1.2 0.77 176 2114 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.01 0.733 – 1.39 0.952 35 681 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1.03 0.926 – 1.15 0.576 350 4233 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 0.961 0.788 – 1.17 0.694 106 1428 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.02 0.999 – 1.03 0.0643 14903 152174 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.07 0.847 – 1.35 0.576 80 944 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.03 0.84 – 1.27 0.76 91 1836 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.05 0.974 – 1.13 0.2 747 8937 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.06 0.949 – 1.17 0.319 358 4573 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.03 0.947 – 1.12 0.468 569 6072 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.945 0.825 – 1.08 0.411 228 2348 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.13 1.01 – 1.26 0.0277 342 3712 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.908 0.751 – 1.1 0.318 113 1129 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.09 0.957 – 1.24 0.196 246 3152 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.04 0.976 – 1.11 0.223 1023 11912 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.04 0.964 – 1.12 0.313 729 8411 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.03 0.951 – 1.12 0.445 639 7478 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.03 0.948 – 1.13 0.454 569 6712 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.944 0.765 – 1.16 0.59 97 1217 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.08 0.989 – 1.18 0.0868 549 6019 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.14 0.966 – 1.35 0.12 155 1621 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.18 0.929 – 1.5 0.175 77 841 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.06 0.922 – 1.22 0.417 219 2330 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.15 0.893 – 1.49 0.273 63 799 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.866 0.718 – 1.04 0.133 119 1395 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.06 0.971 – 1.16 0.185 517 5565 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.15 0.971 – 1.37 0.104 139 1562 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.05 0.833 – 1.33 0.668 74 894 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.23 0.952 – 1.58 0.114 65 672 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.999 0.889 – 1.12 0.992 301 3148 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.998 0.887 – 1.12 0.972 300 3139 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 1.08 0.932 – 1.25 0.311 204 2044 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.09 0.928 – 1.27 0.301 173 1788 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 0.834 0.703 – 0.989 0.0368 147 1512 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.846 0.709 – 1.01 0.0618 140 1430 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.04 0.83 – 1.3 0.74 79 917 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.975 0.807 – 1.18 0.792 123 1279 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.844 0.724 – 0.984 0.0303 173 1774 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.17 0.867 – 1.57 0.309 43 465 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.02 0.946 – 1.11 0.573 699 7303 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 0.994 0.932 – 1.06 0.867 1004 10489 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.966 0.891 – 1.05 0.395 637 6648 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.01 0.903 – 1.12 0.918 370 3848 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.851 0.664 – 1.09 0.2 64 651 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.06 0.922 – 1.22 0.407 200 2079 exclusion phecode
269 Proteinuria Endocrine/metabolic 0.962 0.844 – 1.1 0.564 250 3027 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.08 0.946 – 1.23 0.264 238 2652 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.07 0.931 – 1.23 0.341 206 2291 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.08 0.914 – 1.27 0.378 144 1662 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 0.885 0.716 – 1.1 0.262 90 978 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.07 0.83 – 1.39 0.586 62 602 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.09 0.912 – 1.3 0.348 142 1398 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.09 0.91 – 1.31 0.34 129 1219 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.01 0.994 – 1.02 0.305 30331 208596 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.01 0.994 – 1.02 0.312 30268 208396 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.01 0.994 – 1.02 0.333 28136 202121 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.86 0.644 – 1.15 0.309 50 526 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.06 0.89 – 1.26 0.519 139 1455 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.963 0.832 – 1.12 0.616 186 1892 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.97 0.935 – 1.01 0.11 3086 33973 exclusion phecode
274.1 Gout Endocrine/metabolic 0.981 0.942 – 1.02 0.344 2597 29046 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.922 0.745 – 1.14 0.453 92 1012 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.937 0.858 – 1.02 0.15 538 5459 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.946 0.862 – 1.04 0.239 491 4972 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.03 0.981 – 1.08 0.223 1742 18700 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 1.03 0.941 – 1.12 0.551 565 5841 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.12 0.999 – 1.26 0.0513 303 3331 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.991 0.927 – 1.06 0.783 968 10607 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.03 0.865 – 1.22 0.754 142 1541 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 0.984 0.958 – 1.01 0.238 5811 64584 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 0.981 0.946 – 1.02 0.291 3210 36279 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.05 0.91 – 1.22 0.496 196 2164 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 0.952 0.902 – 1 0.0712 1435 16068 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 0.946 0.876 – 1.02 0.16 680 8740 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.05 0.986 – 1.11 0.132 1169 12538 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.992 0.926 – 1.06 0.813 908 10337 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.01 0.936 – 1.08 0.876 820 9381 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 0.855 0.688 – 1.06 0.155 94 992 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 0.979 0.938 – 1.02 0.331 2288 24958 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 0.976 0.872 – 1.09 0.681 320 4034 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1 0.817 – 1.23 0.977 105 1127 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 0.997 0.924 – 1.08 0.943 734 7860 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.9 0.803 – 1.01 0.0716 324 3266 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.939 0.815 – 1.08 0.378 196 2063 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.98 0.72 – 1.33 0.895 41 462 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1 0.979 – 1.02 0.962 9157 94982 exclusion phecode
278.1 Obesity Endocrine/metabolic 1 0.982 – 1.03 0.782 9021 93569 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 0.799 0.621 – 1.03 0.0795 70 723 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.02 0.78 – 1.34 0.866 53 557 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.952 0.824 – 1.1 0.504 209 2216 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 0.891 0.761 – 1.04 0.149 178 1857 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.859 0.712 – 1.04 0.112 120 1221 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.01 0.877 – 1.16 0.909 221 2254 exclusion phecode
280 Iron deficiency anemias Hematopoietic 0.993 0.968 – 1.02 0.598 6349 66456 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.988 0.962 – 1.01 0.368 6112 63888 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.08 0.967 – 1.21 0.174 360 3895 exclusion phecode
281 Other deficiency anemia Hematopoietic 0.97 0.906 – 1.04 0.38 908 9768 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 0.959 0.894 – 1.03 0.231 873 9374 exclusion phecode
281.11 Pernicious anemia Hematopoietic 0.992 0.913 – 1.08 0.855 616 6556 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.953 0.803 – 1.13 0.582 145 1554 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 0.921 0.78 – 1.09 0.331 149 1667 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.41 1.04 – 1.92 0.028 42 465 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 0.989 0.824 – 1.19 0.902 124 1334 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.05 0.789 – 1.39 0.754 46 504 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.03 0.814 – 1.3 0.805 69 748 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1 0.827 – 1.21 0.982 117 1217 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.971 0.784 – 1.2 0.791 89 944 exclusion phecode
284 Aplastic anemia Hematopoietic 0.914 0.82 – 1.02 0.107 345 3908 exclusion phecode
285 Other anemias Hematopoietic 0.979 0.959 – 0.999 0.0417 9875 105987 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.948 0.823 – 1.09 0.454 218 2336 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 0.971 0.88 – 1.07 0.556 451 6148 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.955 0.854 – 1.07 0.414 349 3619 exclusion phecode
286 Coagulation defects Hematopoietic 0.938 0.871 – 1.01 0.0968 764 8105 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.968 0.872 – 1.07 0.544 391 4006 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 1.01 0.808 – 1.26 0.926 83 859 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.97 0.851 – 1.1 0.643 248 2547 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 0.955 0.725 – 1.26 0.741 55 557 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.852 0.669 – 1.09 0.196 70 753 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.915 0.814 – 1.03 0.138 308 3394 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.02 0.965 – 1.08 0.497 1390 14646 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.87 0.718 – 1.05 0.154 107 1155 exclusion phecode
287.2 Allergic purpura Hematopoietic 1.26 0.948 – 1.67 0.111 45 449 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.02 0.964 – 1.08 0.487 1303 13740 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.06 0.95 – 1.18 0.304 364 3671 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.11 0.845 – 1.45 0.462 54 675 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.02 0.981 – 1.06 0.356 3217 32920 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.02 0.979 – 1.06 0.373 2718 27643 exclusion phecode
288.11 Neutropenia Hematopoietic 1.02 0.979 – 1.06 0.375 2723 27710 exclusion phecode
288.3 Eosinophilia Hematopoietic 0.871 0.68 – 1.12 0.275 63 630 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.01 0.934 – 1.09 0.815 715 7620 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.998 0.873 – 1.14 0.977 245 2534 exclusion phecode
289.4 Lymphadenitis Hematopoietic 0.996 0.954 – 1.04 0.857 2231 22907 exclusion phecode
289.5 Diseases of spleen Hematopoietic 0.902 0.816 – 0.998 0.0449 418 4588 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 0.973 0.854 – 1.11 0.682 238 2636 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 0.957 0.753 – 1.21 0.716 73 804 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.01 0.955 – 1.06 0.809 1573 17094 exclusion phecode
290.1 Dementias Mental Disorders 1 0.935 – 1.08 0.9 836 8856 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.944 0.847 – 1.05 0.295 365 3765 exclusion phecode
290.16 Vascular dementia Mental Disorders 0.989 0.84 – 1.16 0.898 158 1777 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.937 0.858 – 1.02 0.154 535 5820 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.36 1.04 – 1.79 0.0245 61 648 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.02 0.946 – 1.1 0.59 695 7437 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.992 0.822 – 1.2 0.933 111 1144 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.01 0.885 – 1.16 0.853 230 2552 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.05 0.948 – 1.17 0.34 369 3880 exclusion phecode
292 Neurological disorders Mental Disorders 1 0.971 – 1.04 0.824 3917 41132 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.03 0.974 – 1.09 0.288 1279 13321 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.94 0.798 – 1.11 0.459 156 1725 exclusion phecode
292.3 Memory loss Mental Disorders 0.992 0.912 – 1.08 0.844 603 6240 exclusion phecode
292.4 Altered mental status Mental Disorders 1.01 0.966 – 1.06 0.575 1831 19419 exclusion phecode
292.6 Hallucinations Mental Disorders 1.08 0.947 – 1.22 0.264 263 2704 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.03 0.982 – 1.08 0.23 1884 18867 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.04 0.964 – 1.12 0.31 757 7948 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.04 0.96 – 1.12 0.363 703 7497 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.09 0.994 – 1.19 0.0674 487 5155 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.01 0.855 – 1.2 0.888 147 1576 exclusion phecode
295.3 Psychosis Mental Disorders 0.932 0.788 – 1.1 0.414 143 1496 exclusion phecode
296 Mood disorders Mental Disorders 1 0.981 – 1.02 0.906 10454 108267 exclusion phecode
296.1 Bipolar Mental Disorders 1.06 0.987 – 1.13 0.114 880 9349 exclusion phecode
296.2 Depression Mental Disorders 1 0.98 – 1.02 0.993 9918 102662 exclusion phecode
296.22 Major depressive disorder Mental Disorders 0.997 0.886 – 1.12 0.958 306 3155 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.931 0.82 – 1.06 0.264 253 2654 exclusion phecode
300 Anxiety disorders Mental Disorders 1.01 0.987 – 1.04 0.309 5823 59785 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.02 0.991 – 1.05 0.176 5385 55154 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 0.958 0.8 – 1.15 0.641 133 1317 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.994 0.915 – 1.08 0.889 608 6133 exclusion phecode
300.13 Phobia Mental Disorders 1.03 0.937 – 1.14 0.505 420 4343 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.897 0.744 – 1.08 0.252 119 1246 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1 0.74 – 1.36 0.991 45 462 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 0.879 0.718 – 1.08 0.214 108 1100 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.942 0.766 – 1.16 0.575 99 1025 exclusion phecode
301 Personality disorders Mental Disorders 0.941 0.832 – 1.06 0.326 284 2946 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.915 0.752 – 1.11 0.375 105 1029 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 1.17 1.02 – 1.33 0.0207 255 2634 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.987 0.891 – 1.09 0.802 404 4083 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.982 0.872 – 1.1 0.759 305 3046 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.969 0.794 – 1.18 0.753 102 1074 exclusion phecode
304 Adjustment reaction Mental Disorders 0.997 0.877 – 1.13 0.965 256 2598 exclusion phecode
305.2 Eating disorder Mental Disorders 1.33 1.03 – 1.72 0.0271 68 757 exclusion phecode
306 Other mental disorder Mental Disorders 1.02 1 – 1.03 0.0135 24337 203880 exclusion phecode
306.9 Tension headache Mental Disorders 1.04 0.921 – 1.18 0.505 268 2697 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.981 0.77 – 1.25 0.876 69 691 exclusion phecode
313.3 Autism Mental Disorders 0.914 0.69 – 1.21 0.53 50 483 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.01 0.9 – 1.14 0.821 296 3134 exclusion phecode
315.1 Learning disorder Mental Disorders 1.07 0.888 – 1.28 0.494 130 1452 exclusion phecode
315.2 Speech and language disorder Mental Disorders 1.05 0.831 – 1.32 0.692 78 767 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1 0.971 – 1.03 0.941 4539 48314 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.44 1.09 – 1.9 0.011 48 527 exclusion phecode
317 Alcohol-related disorders Mental Disorders 0.998 0.979 – 1.02 0.836 11052 114121 exclusion phecode
317.1 Alcoholism Mental Disorders 1 0.98 – 1.03 0.789 7765 79961 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 0.969 0.895 – 1.05 0.432 654 7680 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.02 1.01 – 1.04 0.0078 16528 165190 exclusion phecode
320 Meningitis Neurological 1 0.902 – 1.12 0.932 373 3938 exclusion phecode
323 Encephalitis Neurological 0.941 0.834 – 1.06 0.324 287 3026 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 0.962 0.753 – 1.23 0.757 65 640 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.04 0.907 – 1.2 0.544 215 2588 exclusion phecode
327 Sleep disorders Neurological 0.979 0.918 – 1.04 0.52 1036 10451 exclusion phecode
327.3 Sleep apnea Neurological 0.985 0.953 – 1.02 0.368 3910 40063 exclusion phecode
327.4 Insomnia Neurological 1.02 0.864 – 1.2 0.815 142 1449 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.05 0.879 – 1.26 0.566 116 1206 exclusion phecode
331 Other cerebral degenerations Neurological 0.993 0.928 – 1.06 0.826 938 10094 exclusion phecode
331.1 Hydrocephalus Neurological 1 0.907 – 1.11 0.926 402 4394 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 0.939 0.842 – 1.05 0.257 350 3854 exclusion phecode
332 Parkinson's disease Neurological 1.01 0.947 – 1.08 0.742 991 10038 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.08 1 – 1.16 0.0497 752 7810 exclusion phecode
333.1 Essential tremor Neurological 1.08 0.928 – 1.26 0.313 184 1877 exclusion phecode
333.2 Myoclonus Neurological 0.901 0.714 – 1.14 0.381 81 845 exclusion phecode
333.4 Torsion dystonia Neurological 1.13 0.98 – 1.3 0.0936 213 2162 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 0.979 0.929 – 1.03 0.421 1558 16173 exclusion phecode
334.1 Spinocerebellar disease Neurological 0.97 0.785 – 1.2 0.776 94 1053 exclusion phecode
334.2 Anterior horn cell disease Neurological 0.994 0.866 – 1.14 0.931 223 2196 exclusion phecode
335 Multiple sclerosis Neurological 0.995 0.933 – 1.06 0.885 1035 11552 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 0.998 0.872 – 1.14 0.974 223 2370 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.01 0.773 – 1.31 0.965 56 634 exclusion phecode
338 Pain Neurological 0.973 0.898 – 1.05 0.499 659 6766 exclusion phecode
338.1 Acute pain Neurological 1.02 0.913 – 1.14 0.72 338 3495 exclusion phecode
338.2 Chronic pain Neurological 0.953 0.848 – 1.07 0.413 326 3355 exclusion phecode
339 Other headache syndromes Neurological 1.01 0.983 – 1.03 0.523 6706 68201 exclusion phecode
340 Migraine Neurological 0.98 0.94 – 1.02 0.335 2446 24557 exclusion phecode
340.1 Migrain with aura Neurological 0.903 0.779 – 1.05 0.178 188 1829 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.952 0.823 – 1.1 0.512 208 2209 exclusion phecode
342 Hemiplegia Neurological 1.04 0.982 – 1.1 0.176 1230 13270 exclusion phecode
343 Infantile cerebral palsy Neurological 1.02 0.85 – 1.22 0.828 121 1289 exclusion phecode
344 Other paralytic syndromes Neurological 0.972 0.888 – 1.07 0.548 509 5869 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1 0.972 – 1.04 0.849 4170 44589 exclusion phecode
345.1 Epilepsy Neurological 0.979 0.906 – 1.06 0.596 712 7680 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 0.993 0.892 – 1.11 0.903 357 3892 exclusion phecode
345.12 Partial epilepsy Neurological 0.934 0.812 – 1.08 0.342 220 2441 exclusion phecode
345.3 Convulsions Neurological 0.976 0.93 – 1.02 0.309 1861 19916 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.09 0.908 – 1.31 0.348 119 1263 exclusion phecode
348 Other conditions of brain Neurological 0.918 0.847 – 0.995 0.0376 641 6919 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 0.905 0.791 – 1.03 0.143 230 2334 exclusion phecode
348.4 Cerebral cysts Neurological 1.05 0.863 – 1.27 0.639 111 1180 exclusion phecode
348.7 Coma Neurological 1.09 0.966 – 1.22 0.165 305 3237 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 0.865 0.749 – 1 0.0496 198 2241 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.08 0.968 – 1.21 0.166 327 3462 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.944 0.836 – 1.07 0.36 293 3009 exclusion phecode
350 Abnormal movement Neurological 1.03 0.983 – 1.07 0.234 2243 23671 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.04 0.962 – 1.12 0.331 749 7788 exclusion phecode
350.2 Abnormality of gait Neurological 1.03 0.975 – 1.09 0.285 1332 14156 exclusion phecode
350.3 Lack of coordination Neurological 0.985 0.874 – 1.11 0.798 299 3251 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.943 0.702 – 1.27 0.695 47 480 exclusion phecode
351 Other peripheral nerve disorders Neurological 0.981 0.962 – 1 0.0669 10583 107573 exclusion phecode
352 Disorders of other cranial nerves Neurological 0.965 0.909 – 1.03 0.248 1171 11985 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.936 0.843 – 1.04 0.214 387 4017 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 0.997 0.925 – 1.07 0.928 764 7729 exclusion phecode
353 Nerve root and plexus disorders Neurological 0.979 0.916 – 1.05 0.533 955 9935 exclusion phecode
353.1 Nerve plexus lesions Neurological 1.05 0.86 – 1.28 0.638 101 1009 exclusion phecode
353.2 Nerve root lesions Neurological 0.867 0.646 – 1.16 0.339 50 502 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.922 0.762 – 1.12 0.408 116 1353 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 0.942 0.886 – 1 0.0556 1141 12201 exclusion phecode
358 Myoneural disorders Neurological 0.914 0.781 – 1.07 0.259 168 1857 exclusion phecode
358.1 Myasthenia gravis Neurological 0.948 0.805 – 1.12 0.518 154 1680 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.916 0.822 – 1.02 0.11 355 4100 exclusion phecode
359.1 Muscular dystrophies Neurological 1.04 0.841 – 1.29 0.697 81 1090 exclusion phecode
359.2 Myopathy Neurological 0.889 0.788 – 1 0.0547 285 3166 exclusion phecode
360 Disorders of the globe Sense Organs 0.902 0.797 – 1.02 0.104 287 2945 exclusion phecode
360.2 Progressive myopia Sense Organs 0.853 0.737 – 0.989 0.0349 210 2193 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.986 0.949 – 1.02 0.473 2893 28939 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.977 0.922 – 1.04 0.431 1250 12375 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 1.25 0.976 – 1.6 0.0772 60 600 exclusion phecode
362 Other retinal disorders Sense Organs 1.01 0.978 – 1.05 0.446 3250 33678 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.999 0.952 – 1.05 0.958 1853 19021 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.998 0.952 – 1.05 0.95 1850 18994 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.831 0.697 – 0.99 0.0387 135 1426 exclusion phecode
362.31 Separation of retinal layers Sense Organs 0.814 0.656 – 1.01 0.0625 90 878 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.04 0.965 – 1.12 0.293 711 7480 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 1.09 0.923 – 1.28 0.317 154 1627 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.21 0.943 – 1.54 0.135 74 723 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.1 0.895 – 1.34 0.378 99 1028 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.923 0.776 – 1.1 0.368 141 1518 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.993 0.753 – 1.31 0.958 56 608 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.01 0.922 – 1.1 0.889 550 5634 exclusion phecode
364.1 Corneal opacity Sense Organs 1.02 0.816 – 1.27 0.864 82 826 exclusion phecode
364.2 Corneal edema Sense Organs 1.2 0.937 – 1.54 0.148 69 702 exclusion phecode
364.4 Corneal degenerations Sense Organs 0.976 0.832 – 1.15 0.767 173 1768 exclusion phecode
364.41 Keratoconus Sense Organs 0.917 0.729 – 1.15 0.457 75 765 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.982 0.843 – 1.14 0.811 177 1819 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 1.18 0.948 – 1.47 0.139 82 874 exclusion phecode
365 Glaucoma Sense Organs 1.01 0.973 – 1.04 0.72 3772 38791 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 1 0.936 – 1.07 0.943 893 9143 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 1 0.937 – 1.08 0.901 888 9087 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.948 0.872 – 1.03 0.216 587 6118 exclusion phecode
366 Cataract Sense Organs 0.993 0.977 – 1.01 0.366 17088 148148 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.905 0.686 – 1.19 0.483 55 615 exclusion phecode
366.2 Senile cataract Sense Organs 0.999 0.974 – 1.02 0.915 7029 71519 exclusion phecode
366.3 Traumatic cataract Sense Organs 0.902 0.729 – 1.12 0.343 93 940 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.98 0.937 – 1.03 0.385 2055 21183 exclusion phecode
367.1 Myopia Sense Organs 0.96 0.902 – 1.02 0.201 1089 11001 exclusion phecode
367.2 Astigmatism Sense Organs 0.954 0.815 – 1.12 0.555 164 1645 exclusion phecode
367.8 Hypermetropia Sense Organs 1.02 0.883 – 1.17 0.825 210 2211 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.01 0.931 – 1.1 0.766 602 6385 exclusion phecode
368 Visual disturbances Sense Organs 1.03 0.987 – 1.07 0.186 2532 26060 exclusion phecode
368.1 Amblyopia Sense Organs 1.06 0.962 – 1.17 0.232 451 4670 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.971 0.893 – 1.06 0.49 612 6471 exclusion phecode
368.3 Anisometropia Sense Organs 0.908 0.762 – 1.08 0.282 139 1382 exclusion phecode
368.4 Visual field defects Sense Organs 0.941 0.832 – 1.07 0.338 286 2980 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 1.06 0.968 – 1.16 0.209 514 5358 exclusion phecode
369 Infection of the eye Sense Organs 0.976 0.888 – 1.07 0.605 473 4883 exclusion phecode
369.2 Eye infection, viral Sense Organs 1.01 0.835 – 1.23 0.897 110 1130 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 1.05 0.902 – 1.22 0.529 175 1871 exclusion phecode
370 Keratitis Sense Organs 1.11 0.968 – 1.28 0.133 238 2492 exclusion phecode
370.1 Corneal ulcer Sense Organs 1.31 1.07 – 1.59 0.00752 119 1243 exclusion phecode
371 Inflammation of the eye Sense Organs 1 0.965 – 1.04 0.841 2669 26805 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.04 0.944 – 1.15 0.404 422 4237 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 1.01 0.963 – 1.05 0.741 2070 20757 exclusion phecode
372 Disorders of conjunctiva Sense Organs 0.931 0.858 – 1.01 0.082 659 6679 exclusion phecode
374 Other disorders of eyelids Sense Organs 1.02 0.988 – 1.05 0.246 4921 49751 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.979 0.914 – 1.05 0.531 930 9466 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 1.02 0.965 – 1.07 0.538 1583 15862 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.977 0.932 – 1.02 0.341 1889 19015 exclusion phecode
375.2 Epiphora Sense Organs 0.99 0.92 – 1.07 0.792 782 7702 exclusion phecode
376 Disorders of the orbit Sense Organs 0.868 0.681 – 1.11 0.25 72 755 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.933 0.827 – 1.05 0.257 305 3155 exclusion phecode
377.1 Optic atrophy Sense Organs 0.972 0.724 – 1.3 0.848 47 513 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.948 0.778 – 1.16 0.596 106 1094 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.01 0.952 – 1.07 0.731 1206 12481 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.03 0.954 – 1.1 0.49 779 7967 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.98 0.843 – 1.14 0.797 181 1942 exclusion phecode
378.5 Paralytic strabismus Sense Organs 0.972 0.847 – 1.11 0.681 234 2439 exclusion phecode
379 Other disorders of eye Sense Organs 0.983 0.948 – 1.02 0.358 3183 32429 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 1.01 0.952 – 1.07 0.732 1176 12026 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.959 0.91 – 1.01 0.116 1559 15821 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.19 0.917 – 1.54 0.193 64 623 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.01 0.905 – 1.13 0.85 338 3548 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.18 0.994 – 1.41 0.0584 142 1488 exclusion phecode
380 Disorders of external ear Sense Organs 0.978 0.897 – 1.07 0.62 573 5673 exclusion phecode
380.1 Otitis externa Sense Organs 0.932 0.845 – 1.03 0.157 431 4511 exclusion phecode
380.4 Impacted cerumen Sense Organs 0.906 0.807 – 1.02 0.0931 315 3150 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.98 0.934 – 1.03 0.412 1868 18967 exclusion phecode
381.1 Otitis media Sense Organs 0.979 0.928 – 1.03 0.421 1541 15597 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1 0.928 – 1.08 0.972 742 7562 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 1.05 0.898 – 1.23 0.529 173 1672 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.884 0.741 – 1.06 0.174 143 1514 exclusion phecode
381.9 Otorrhea Sense Organs 0.988 0.865 – 1.13 0.858 238 2485 exclusion phecode
382 Otalgia Sense Organs 0.985 0.869 – 1.12 0.807 277 2689 exclusion phecode
383 Otosclerosis Sense Organs 1.05 0.927 – 1.19 0.433 274 2694 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.02 0.958 – 1.08 0.556 1153 11415 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.05 0.98 – 1.12 0.167 923 9151 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.971 0.897 – 1.05 0.471 699 6956 exclusion phecode
385.3 Cholesteatoma Sense Organs 0.972 0.888 – 1.06 0.542 538 5413 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.01 0.88 – 1.16 0.862 221 2078 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.01 0.957 – 1.06 0.733 1498 15257 exclusion phecode
386.1 Meniere's disease Sense Organs 1.02 0.927 – 1.12 0.713 505 5059 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 1 0.892 – 1.12 0.982 321 3294 exclusion phecode
386.3 Labyrinthitis Sense Organs 0.986 0.91 – 1.07 0.719 663 6716 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.01 0.979 – 1.05 0.498 3917 40313 exclusion phecode
388 Other disorders of ear Sense Organs 1.08 0.923 – 1.26 0.342 175 1771 exclusion phecode
389 Hearing loss Sense Organs 0.988 0.955 – 1.02 0.493 3633 36997 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.98 0.883 – 1.09 0.705 396 3972 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.04 0.937 – 1.15 0.461 390 3933 exclusion phecode
389.4 Tinnitus Sense Organs 1.06 0.965 – 1.17 0.212 447 4541 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.02 0.992 – 1.06 0.143 4189 43700 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.01 0.97 – 1.05 0.621 2563 26621 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.06 0.995 – 1.13 0.0712 1092 11512 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 0.994 0.928 – 1.06 0.859 890 9395 exclusion phecode
395 Heart valve disorders Circulatory System 1.03 0.992 – 1.06 0.139 3611 37653 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.01 0.971 – 1.05 0.589 2478 25750 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.09 0.95 – 1.24 0.226 236 2487 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 0.968 0.788 – 1.19 0.757 92 935 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.02 0.818 – 1.27 0.869 86 867 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.09 1.02 – 1.15 0.00576 1263 13409 exclusion phecode
396 Abnormal heart sounds Circulatory System 0.998 0.929 – 1.07 0.948 860 9001 exclusion phecode
401 Hypertension Circulatory System 0.995 0.986 – 1 0.238 63789 236404 exclusion phecode
401.1 Essential hypertension Circulatory System 0.995 0.986 – 1 0.243 63652 236218 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 0.946 0.889 – 1.01 0.0846 1064 17193 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.07 0.954 – 1.21 0.238 304 3351 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.894 0.83 – 0.962 0.00289 762 13962 exclusion phecode
401.3 Other hypertensive complications Circulatory System 0.906 0.71 – 1.16 0.425 66 1297 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1 0.945 – 1.06 0.983 1288 13235 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.02 1 – 1.03 0.0152 27378 187719 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.04 1.01 – 1.08 0.00649 4500 46324 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.03 1.01 – 1.05 0.0113 10481 102509 exclusion phecode
411.3 Angina pectoris Circulatory System 1.02 1 – 1.04 0.0293 13846 128599 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.02 1 – 1.03 0.0323 17835 139619 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.987 0.908 – 1.07 0.756 628 6282 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.03 1.01 – 1.05 0.00229 13213 118710 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.985 0.925 – 1.05 0.642 1068 11061 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.04 0.987 – 1.09 0.14 1562 16642 exclusion phecode
414.2 ASCVD Circulatory System 1.05 0.802 – 1.36 0.742 58 649 exclusion phecode
415 Pulmonary heart disease Circulatory System 0.986 0.954 – 1.02 0.411 3842 39713 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.01 0.785 – 1.31 0.916 62 650 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.07 0.972 – 1.17 0.176 486 5322 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.04 0.93 – 1.16 0.514 363 3959 exclusion phecode
416 Cardiomegaly Circulatory System 1.05 1.01 – 1.1 0.0205 2267 24073 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.01 1 – 1.03 0.033 24898 238459 exclusion phecode
418.1 Precordial pain Circulatory System 1.02 0.978 – 1.05 0.425 3073 31384 exclusion phecode
420 Carditis Circulatory System 0.981 0.935 – 1.03 0.443 1825 18793 exclusion phecode
420.1 Myocarditis Circulatory System 0.961 0.793 – 1.17 0.689 110 1135 exclusion phecode
420.2 Pericarditis Circulatory System 0.983 0.925 – 1.04 0.57 1167 11976 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.02 0.883 – 1.18 0.798 204 2006 exclusion phecode
420.22 Chronic pericarditis Circulatory System 0.974 0.794 – 1.19 0.801 102 1000 exclusion phecode
420.3 Endocarditis Circulatory System 1.02 0.936 – 1.11 0.686 612 6385 exclusion phecode
425 Cardiomyopathy Circulatory System 1.12 1.05 – 1.19 0.000392 1062 11415 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.11 1.04 – 1.18 0.00177 1036 11097 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.16 0.967 – 1.4 0.108 113 1217 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.08 0.913 – 1.28 0.36 143 1473 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.57 1.19 – 2.08 0.00151 52 557 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.03 1 – 1.06 0.034 5929 62038 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.03 0.982 – 1.08 0.221 1812 19091 exclusion phecode
426.21 First degree AV block Circulatory System 1.03 0.956 – 1.1 0.489 841 8928 exclusion phecode
426.23 Second degree AV block Circulatory System 1.08 0.972 – 1.2 0.151 391 4055 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 0.988 0.902 – 1.08 0.802 502 5261 exclusion phecode
426.25 Other heart block Circulatory System 0.896 0.746 – 1.08 0.242 116 1179 exclusion phecode
426.3 Bundle branch block Circulatory System 1.03 0.993 – 1.07 0.114 2832 29861 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.02 0.958 – 1.08 0.609 1286 13410 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.05 0.992 – 1.1 0.0987 1460 15576 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.1 0.958 – 1.27 0.173 210 2065 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.21 0.911 – 1.6 0.189 53 527 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.08 1.03 – 1.13 0.00105 2099 22312 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.08 1.03 – 1.13 0.00195 1927 20475 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.02 1 – 1.03 0.0385 20987 182754 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.01 0.973 – 1.05 0.566 2733 28447 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.01 0.96 – 1.05 0.829 2010 20737 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.04 0.964 – 1.12 0.32 782 8487 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.02 1.01 – 1.04 0.00885 12775 119791 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.02 0.982 – 1.06 0.303 2844 28847 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1 0.94 – 1.07 0.92 995 10777 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.06 0.943 – 1.19 0.322 302 3146 exclusion phecode
427.42 Cardiac arrest Circulatory System 0.998 0.929 – 1.07 0.948 818 8946 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.02 0.947 – 1.09 0.656 835 8463 exclusion phecode
427.6 Premature beats Circulatory System 1.09 0.989 – 1.19 0.0843 469 4786 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 0.962 0.777 – 1.19 0.719 99 1049 exclusion phecode
427.7 Tachycardia NOS Circulatory System 0.996 0.949 – 1.05 0.878 1810 19335 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.1 0.985 – 1.23 0.0912 357 3579 exclusion phecode
427.9 Palpitations Circulatory System 1.01 0.971 – 1.04 0.721 3272 33286 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.06 1.03 – 1.09 7.19e-05 4644 50470 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.07 1.02 – 1.13 0.00626 1677 19016 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.06 1.03 – 1.1 0.000335 3707 40071 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1 0.922 – 1.09 0.983 628 6356 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.4 1.03 – 1.91 0.0325 39 579 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1 0.912 – 1.1 0.939 456 4637 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.01 0.867 – 1.18 0.876 174 1730 exclusion phecode
430 Intracranial hemorrhage Circulatory System 0.987 0.937 – 1.04 0.604 1610 16638 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.977 0.904 – 1.06 0.56 707 7216 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 0.958 0.884 – 1.04 0.287 656 6822 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.1 0.955 – 1.26 0.191 226 2379 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.01 0.986 – 1.03 0.423 7465 77829 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.02 0.957 – 1.09 0.53 1000 10559 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1 0.863 – 1.17 0.967 185 2022 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.01 0.981 – 1.05 0.4 3633 37777 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.03 0.977 – 1.09 0.258 1437 14989 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1 0.964 – 1.05 0.842 2483 25761 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 0.994 0.947 – 1.04 0.8 1844 18989 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1 0.892 – 1.12 0.979 322 3384 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.09 1.02 – 1.16 0.00677 1047 11332 exclusion phecode
440 Atherosclerosis Circulatory System 0.959 0.902 – 1.02 0.177 1113 12510 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.03 0.793 – 1.33 0.831 60 1004 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.963 0.889 – 1.04 0.347 662 7365 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 0.885 0.773 – 1.01 0.0758 233 2568 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 0.994 0.907 – 1.09 0.903 509 5365 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.03 0.905 – 1.18 0.639 241 2476 exclusion phecode
442 Other aneurysm Circulatory System 1.01 0.963 – 1.07 0.611 1628 17132 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.01 0.955 – 1.07 0.686 1256 13299 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.993 0.923 – 1.07 0.851 784 8506 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 0.999 0.8 – 1.25 0.991 82 913 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.1 0.929 – 1.31 0.264 145 1529 exclusion phecode
442.4 Arterial dissection Circulatory System 0.922 0.696 – 1.22 0.57 49 485 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 0.9 0.768 – 1.05 0.193 172 1770 exclusion phecode
443 Peripheral vascular disease Circulatory System 0.976 0.941 – 1.01 0.186 3202 35052 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.01 0.941 – 1.08 0.85 932 9885 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.983 0.87 – 1.11 0.776 270 3525 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 0.968 0.933 – 1 0.0882 3032 32893 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.954 0.913 – 0.997 0.0364 2126 23343 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 0.958 0.89 – 1.03 0.257 764 8359 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.907 0.825 – 0.997 0.0439 459 5070 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.06 0.979 – 1.15 0.155 677 7217 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.983 0.832 – 1.16 0.84 149 1669 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.1 0.983 – 1.24 0.0949 324 3346 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.04 0.898 – 1.2 0.616 198 2139 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 0.96 0.902 – 1.02 0.196 1084 11968 exclusion phecode
447.1 Stricture of artery Circulatory System 0.962 0.893 – 1.04 0.32 723 7900 exclusion phecode
448 Disease of capillaries Circulatory System 1.03 0.856 – 1.24 0.754 120 1255 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.977 0.895 – 1.07 0.596 564 6146 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.981 0.947 – 1.02 0.293 3419 35273 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.973 0.938 – 1.01 0.144 3184 32896 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 1.01 0.914 – 1.11 0.916 470 5038 exclusion phecode
454 Varicose veins Circulatory System 1.01 0.993 – 1.04 0.188 9660 97444 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1.02 1 – 1.04 0.04 9932 99886 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.03 0.945 – 1.13 0.474 525 5594 exclusion phecode
455 Hemorrhoids Circulatory System 1 0.99 – 1.02 0.527 20567 207066 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.939 0.798 – 1.1 0.446 153 1651 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.953 0.759 – 1.2 0.678 84 861 exclusion phecode
458 Hypotension Circulatory System 0.991 0.962 – 1.02 0.54 4821 51073 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 0.956 0.9 – 1.02 0.147 1138 11918 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.07 0.926 – 1.24 0.352 197 2079 exclusion phecode
458.9 Hypotension NOS Circulatory System 0.983 0.947 – 1.02 0.393 2902 30887 exclusion phecode
459 Other disorders of circulatory system Circulatory System 0.993 0.976 – 1.01 0.446 13833 142591 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 0.92 0.763 – 1.11 0.382 120 1258 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 0.995 0.977 – 1.01 0.565 13700 141369 exclusion phecode
464 Acute sinusitis Respiratory 0.92 0.781 – 1.08 0.319 164 1714 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.01 0.963 – 1.06 0.715 1954 19959 exclusion phecode
465.2 Acute pharyngitis Respiratory 1.01 0.931 – 1.09 0.873 714 7309 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.984 0.834 – 1.16 0.85 150 1445 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.02 0.992 – 1.06 0.138 4190 41856 exclusion phecode
471 Nasal polyps Respiratory 1.03 0.992 – 1.07 0.118 2964 29684 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.992 0.924 – 1.06 0.825 843 8502 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 0.982 0.94 – 1.03 0.401 2232 22502 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.01 0.816 – 1.25 0.924 93 907 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.938 0.819 – 1.07 0.358 225 2348 exclusion phecode
473.4 Voice disturbance Respiratory 0.99 0.926 – 1.06 0.778 940 9468 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 0.946 0.898 – 0.996 0.0356 1574 15672 exclusion phecode
474.1 Acute tonsillitis Respiratory 0.931 0.845 – 1.02 0.142 472 4807 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.951 0.891 – 1.01 0.126 1013 9836 exclusion phecode
475 Chronic sinusitis Respiratory 1.01 0.965 – 1.05 0.694 2257 22885 exclusion phecode
476 Allergic rhinitis Respiratory 1.03 0.959 – 1.1 0.456 921 9306 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.02 0.972 – 1.06 0.477 2109 21774 exclusion phecode
478 Throat pain Respiratory 0.964 0.86 – 1.08 0.526 330 3302 exclusion phecode
479 Other upper respiratory disease Respiratory 1.02 0.988 – 1.06 0.201 3591 36249 exclusion phecode
480 Pneumonia Respiratory 1 0.978 – 1.02 0.967 8662 91949 exclusion phecode
480.1 Bacterial pneumonia Respiratory 0.998 0.971 – 1.03 0.908 5572 58972 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 0.995 0.966 – 1.02 0.715 4939 52253 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.11 0.876 – 1.4 0.396 73 816 exclusion phecode
480.2 Viral pneumonia Respiratory 1.15 0.872 – 1.51 0.325 58 648 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.06 0.852 – 1.32 0.596 83 890 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.977 0.903 – 1.06 0.573 658 7092 exclusion phecode
481 Influenza Respiratory 0.959 0.847 – 1.09 0.515 277 2914 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.994 0.848 – 1.17 0.943 161 1706 exclusion phecode
495 Asthma Respiratory 1 0.988 – 1.02 0.768 22131 219282 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.06 0.922 – 1.22 0.407 211 2175 exclusion phecode
496 Chronic airway obstruction Respiratory 0.991 0.97 – 1.01 0.442 8804 89879 exclusion phecode
496.1 Emphysema Respiratory 0.961 0.911 – 1.01 0.139 1464 15553 exclusion phecode
496.2 Chronic bronchitis Respiratory 0.965 0.926 – 1.01 0.0878 2469 26161 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 0.98 0.939 – 1.02 0.363 2260 24029 exclusion phecode
496.3 Bronchiectasis Respiratory 1.01 0.964 – 1.07 0.573 1584 16541 exclusion phecode
497 Bronchitis Respiratory 0.928 0.851 – 1.01 0.0928 540 5480 exclusion phecode
500 Lung disease due to external agents Respiratory 0.914 0.822 – 1.02 0.101 360 3700 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.959 0.755 – 1.22 0.731 69 681 exclusion phecode
500.2 Pneumoconiosis Respiratory 0.864 0.752 – 0.992 0.0379 215 2210 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 0.985 0.903 – 1.07 0.733 554 5878 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.967 0.898 – 1.04 0.369 777 8101 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.09 0.986 – 1.21 0.0898 385 4483 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.878 0.775 – 0.994 0.0395 276 2857 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 0.736 0.544 – 0.997 0.0476 49 535 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.03 0.961 – 1.1 0.443 956 10228 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.01 0.978 – 1.03 0.694 5402 57184 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.987 0.939 – 1.04 0.593 1707 17627 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.998 0.954 – 1.04 0.926 2094 23208 exclusion phecode
509.1 Respiratory failure Respiratory 0.988 0.94 – 1.04 0.637 1670 18442 exclusion phecode
509.2 Respiratory insufficiency Respiratory 0.986 0.934 – 1.04 0.61 1457 16078 exclusion phecode
509.5 Respiratory arrest Respiratory 1.06 0.879 – 1.29 0.525 109 1277 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.997 0.888 – 1.12 0.963 316 3466 exclusion phecode
510 Other diseases of lung Respiratory 0.989 0.912 – 1.07 0.786 645 6627 exclusion phecode
512 Other symptoms of respiratory system Respiratory 0.99 0.967 – 1.01 0.389 7697 79396 exclusion phecode
512.1 Wheezing Respiratory 0.992 0.853 – 1.15 0.919 189 1898 exclusion phecode
512.2 Painful respiration Respiratory 1.06 0.915 – 1.23 0.427 181 1792 exclusion phecode
512.7 Shortness of breath Respiratory 0.997 0.968 – 1.03 0.837 4936 51469 exclusion phecode
512.8 Cough Respiratory 0.97 0.93 – 1.01 0.156 2450 25228 exclusion phecode
512.9 Other dyspnea Respiratory 1 0.933 – 1.08 0.901 780 8047 exclusion phecode
513 Respiratory abnormalities Respiratory 1.01 0.922 – 1.1 0.881 528 5387 exclusion phecode
513.3 Hypoventilation Respiratory 1 0.791 – 1.27 0.975 67 725 exclusion phecode
513.4 Hyperventilation Respiratory 0.997 0.873 – 1.14 0.964 243 2404 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.04 0.867 – 1.25 0.67 131 1401 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 0.987 0.944 – 1.03 0.579 2099 21850 exclusion phecode
516 Abnormal sputum Respiratory 1.03 0.986 – 1.08 0.17 1822 18967 exclusion phecode
516.1 Hemoptysis Respiratory 1.03 0.984 – 1.08 0.188 1770 18454 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1 0.98 – 1.03 0.808 7892 82669 exclusion phecode
519.2 Respiratory complications Respiratory 1.02 0.902 – 1.16 0.738 268 2917 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.999 0.975 – 1.02 0.921 7456 78145 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.996 0.877 – 1.13 0.957 262 2667 exclusion phecode
520 Disorders of tooth development Digestive 0.968 0.922 – 1.02 0.194 1794 17930 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 1.13 0.828 – 1.53 0.451 44 462 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.964 0.921 – 1.01 0.108 2076 20655 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 0.994 0.955 – 1.04 0.785 2627 26775 exclusion phecode
521.1 Dental caries Digestive 0.993 0.954 – 1.03 0.735 2634 26897 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.02 0.971 – 1.08 0.388 1523 15568 exclusion phecode
522.5 Periapical abscess Digestive 1.02 0.957 – 1.09 0.526 1007 10279 exclusion phecode
523 Gingival and periodontal diseases Digestive 0.984 0.932 – 1.04 0.548 1460 14677 exclusion phecode
523.1 Gingivitis Digestive 1.12 0.91 – 1.37 0.293 95 977 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 0.989 0.927 – 1.06 0.738 1014 10230 exclusion phecode
523.31 Acute periodontitis Digestive 0.988 0.907 – 1.07 0.772 588 5815 exclusion phecode
523.32 Chronic periodontitis Digestive 0.978 0.89 – 1.08 0.646 477 4887 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.998 0.882 – 1.13 0.976 283 2908 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.01 0.889 – 1.15 0.869 261 2675 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.02 0.972 – 1.06 0.494 2308 23392 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.986 0.769 – 1.26 0.909 61 624 exclusion phecode
526 Diseases of the jaws Digestive 1.07 0.991 – 1.15 0.0873 792 8111 exclusion phecode
526.1 Cysts of the jaws Digestive 1.13 1 – 1.28 0.0413 286 2921 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.921 0.7 – 1.21 0.553 54 529 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.01 0.873 – 1.16 0.928 204 2065 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.01 0.871 – 1.16 0.927 198 1988 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 1.06 0.857 – 1.32 0.575 92 976 exclusion phecode
526.9 Jaw disease NOS Digestive 1.11 0.963 – 1.29 0.146 195 2049 exclusion phecode
527 Diseases of the salivary glands Digestive 0.99 0.909 – 1.08 0.817 602 6072 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.17 0.915 – 1.49 0.211 75 733 exclusion phecode
527.2 Sialoadenitis Digestive 0.952 0.848 – 1.07 0.404 320 3194 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.18 0.88 – 1.58 0.271 48 542 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.01 0.834 – 1.24 0.882 106 1047 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1 0.968 – 1.04 0.886 3367 33938 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.02 0.925 – 1.13 0.652 406 4086 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.01 0.908 – 1.13 0.806 332 3411 exclusion phecode
528.12 Oral aphthae Digestive 1.18 0.929 – 1.49 0.177 79 746 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.911 0.774 – 1.07 0.263 155 1565 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.85 0.696 – 1.04 0.109 105 1059 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.847 0.681 – 1.05 0.133 84 803 exclusion phecode
528.5 Diseases of lips Digestive 1.13 1.04 – 1.23 0.00433 598 5951 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.02 0.898 – 1.15 0.81 269 2706 exclusion phecode
528.7 Sialolithiasis Digestive 0.972 0.86 – 1.1 0.648 272 2785 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.01 0.95 – 1.08 0.723 1060 10804 exclusion phecode
529.1 Glossitis Digestive 1.08 0.95 – 1.22 0.248 253 2620 exclusion phecode
530 Diseases of esophagus Digestive 0.993 0.981 – 1 0.241 29139 246234 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.994 0.982 – 1.01 0.356 27276 240204 exclusion phecode
530.11 GERD Digestive 0.993 0.979 – 1.01 0.368 19704 198511 exclusion phecode
530.12 Ulcer of esophagus Digestive 0.999 0.97 – 1.03 0.961 4610 46466 exclusion phecode
530.14 Reflux esophagitis Digestive 0.98 0.959 – 1 0.0683 9192 92494 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.965 0.913 – 1.02 0.208 1417 14866 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 0.96 0.913 – 1.01 0.113 1669 16688 exclusion phecode
530.5 Disorders of esophageal motility Digestive 0.947 0.867 – 1.04 0.234 553 5589 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.991 0.834 – 1.18 0.915 132 1361 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.03 0.91 – 1.16 0.645 280 3072 exclusion phecode
530.9 Heartburn Digestive 0.977 0.93 – 1.03 0.346 1791 18069 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.01 0.983 – 1.04 0.498 6079 63005 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.991 0.906 – 1.08 0.835 537 5713 exclusion phecode
531.2 Gastric ulcer Digestive 1.01 0.974 – 1.04 0.626 3458 36097 exclusion phecode
531.3 Duodenal ulcer Digestive 0.996 0.957 – 1.04 0.859 2605 26807 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.09 0.979 – 1.21 0.118 374 3800 exclusion phecode
532 Dysphagia Digestive 0.993 0.966 – 1.02 0.603 5541 56359 exclusion phecode
535 Gastritis and duodenitis Digestive 1 0.991 – 1.02 0.51 24329 230109 exclusion phecode
535.1 Acute gastritis Digestive 1.03 0.961 – 1.09 0.44 1017 10435 exclusion phecode
535.2 Atrophic gastritis Digestive 0.961 0.857 – 1.08 0.501 326 3280 exclusion phecode
535.6 Duodenitis Digestive 0.992 0.968 – 1.02 0.549 6666 67630 exclusion phecode
535.8 Other specified gastritis Digestive 1.01 0.987 – 1.04 0.34 6950 70704 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.927 0.755 – 1.14 0.466 106 1047 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.06 0.924 – 1.22 0.397 229 2250 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 0.991 0.953 – 1.03 0.633 2888 29917 exclusion phecode
540 Appendiceal conditions Digestive 0.987 0.949 – 1.03 0.511 2736 27348 exclusion phecode
540.1 Appendicitis Digestive 0.995 0.955 – 1.04 0.802 2571 25638 exclusion phecode
540.11 Acute appendicitis Digestive 0.984 0.943 – 1.03 0.474 2313 23043 exclusion phecode
550 Abdominal hernia Digestive 1.02 1.01 – 1.03 0.00254 40193 249397 exclusion phecode
550.1 Inguinal hernia Digestive 1.03 1.01 – 1.05 0.000589 14537 113884 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.01 0.996 – 1.02 0.187 23086 209711 exclusion phecode
550.3 Femoral hernia Digestive 0.963 0.879 – 1.06 0.424 518 5624 exclusion phecode
550.4 Umbilical hernia Digestive 1.02 0.984 – 1.06 0.291 3290 33596 exclusion phecode
550.5 Ventral hernia Digestive 0.998 0.96 – 1.04 0.91 2922 30304 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.03 0.992 – 1.06 0.136 3873 39244 exclusion phecode
555.1 Regional enteritis Digestive 1 0.952 – 1.06 0.892 1508 15275 exclusion phecode
555.2 Ulcerative colitis Digestive 1.03 0.987 – 1.07 0.19 2772 28168 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.05 0.957 – 1.15 0.296 478 4760 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.02 0.948 – 1.09 0.664 909 9328 exclusion phecode
556.1 Ulceration of intestine Digestive 1.03 0.941 – 1.12 0.558 569 5884 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.938 0.821 – 1.07 0.346 250 2612 exclusion phecode
557.1 Celiac disease Digestive 0.858 0.814 – 0.905 1.57e-08 1521 16070 exclusion phecode
558 Noninfectious gastroenteritis Digestive 0.996 0.978 – 1.01 0.66 13168 135805 exclusion phecode
559 Ileostomy status Digestive 1 0.949 – 1.06 0.914 1419 14720 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1 0.966 – 1.04 0.945 3323 34463 exclusion phecode
560.1 Paralytic ileus Digestive 1.04 0.943 – 1.15 0.436 450 4660 exclusion phecode
560.2 Impaction of intestine Digestive 1.05 0.916 – 1.21 0.467 213 2320 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.995 0.92 – 1.08 0.904 694 7243 exclusion phecode
560.4 Other intestinal obstruction Digestive 0.998 0.96 – 1.04 0.914 2834 29336 exclusion phecode
561 Symptoms involving digestive system Digestive 0.997 0.979 – 1.01 0.736 13504 137400 exclusion phecode
561.1 Diarrhea Digestive 0.916 0.825 – 1.02 0.0975 385 4027 exclusion phecode
561.2 Flatulence Digestive 1.03 0.976 – 1.09 0.286 1425 14754 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1 0.988 – 1.02 0.78 23236 186976 exclusion phecode
562.1 Diverticulosis Digestive 1 0.988 – 1.02 0.766 23202 186930 exclusion phecode
563 Constipation Digestive 0.998 0.976 – 1.02 0.853 8725 90241 exclusion phecode
564 Functional digestive disorders Digestive 1.01 0.992 – 1.02 0.359 18662 184843 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 0.993 0.963 – 1.02 0.652 4672 47494 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.01 0.952 – 1.06 0.832 1386 14384 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.01 0.99 – 1.03 0.391 13175 134330 exclusion phecode
565 Anal and rectal conditions Digestive 1 0.983 – 1.02 0.888 12955 130888 exclusion phecode
565.1 Anal and rectal polyp Digestive 0.998 0.972 – 1.02 0.865 6485 65427 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 0.979 0.909 – 1.06 0.582 737 8206 exclusion phecode
568 Other disorders of peritoneum Digestive 1.02 0.983 – 1.06 0.275 2753 28314 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.02 0.978 – 1.06 0.371 2615 26887 exclusion phecode
569 Other disorders of intestine Digestive 0.973 0.94 – 1.01 0.125 3570 36839 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1 0.837 – 1.2 0.983 126 1263 exclusion phecode
569.2 Gastrointestinal complications Digestive 0.987 0.892 – 1.09 0.805 405 4285 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 0.97 0.93 – 1.01 0.157 2405 26336 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 0.967 0.916 – 1.02 0.24 1404 14953 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.79 0.647 – 0.966 0.0216 94 1027 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 0.997 0.867 – 1.15 0.968 215 2190 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.935 0.868 – 1.01 0.0777 764 8821 exclusion phecode
571.81 Portal hypertension Digestive 0.947 0.855 – 1.05 0.289 408 4760 exclusion phecode
572 Ascites (non malignant) Digestive 1.01 0.954 – 1.07 0.699 1244 13611 exclusion phecode
573 Other disorders of liver Digestive 0.989 0.933 – 1.05 0.717 1243 13216 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.1 0.868 – 1.38 0.441 69 875 exclusion phecode
573.3 Hepatomegaly Digestive 1.04 0.915 – 1.19 0.532 240 2643 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 0.957 0.888 – 1.03 0.246 770 8007 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 0.977 0.941 – 1.01 0.231 2945 30586 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 0.935 0.806 – 1.09 0.378 182 1873 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.01 0.99 – 1.03 0.367 13358 134633 exclusion phecode
574.1 Cholelithiasis Digestive 1 0.984 – 1.02 0.767 11585 116721 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.02 0.963 – 1.08 0.504 1279 13080 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1 0.972 – 1.03 0.895 4665 46734 exclusion phecode
574.2 Calculus of bile duct Digestive 1.01 0.97 – 1.06 0.546 2246 22730 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.04 0.992 – 1.08 0.107 2341 23953 exclusion phecode
575 Other biliary tract disease Digestive 1.02 0.985 – 1.06 0.267 3284 33572 exclusion phecode
575.1 Cholangitis Digestive 0.937 0.848 – 1.04 0.208 419 4416 exclusion phecode
575.2 Obstruction of bile duct Digestive 1 0.924 – 1.09 0.969 669 6827 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.97 0.876 – 1.07 0.553 401 3955 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.04 0.976 – 1.1 0.239 1189 12160 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.05 0.978 – 1.13 0.182 865 8964 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.07 0.954 – 1.21 0.239 291 3019 exclusion phecode
577 Diseases of pancreas Digestive 0.983 0.942 – 1.03 0.439 2287 23522 exclusion phecode
577.1 Acute pancreatitis Digestive 0.969 0.922 – 1.02 0.219 1725 17574 exclusion phecode
577.2 Chronic pancreatitis Digestive 0.922 0.834 – 1.02 0.109 424 4647 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.912 0.812 – 1.03 0.123 315 3205 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.994 – 1.03 0.21 17931 182156 exclusion phecode
578.1 Hematemesis Digestive 0.996 0.947 – 1.05 0.869 1667 17532 exclusion phecode
578.2 Blood in stool Digestive 1.02 0.98 – 1.07 0.289 2258 23380 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.01 0.994 – 1.03 0.175 11364 115051 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1.02 0.992 – 1.05 0.143 4583 46649 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.983 0.928 – 1.04 0.564 1301 13492 exclusion phecode
579.2 Splenomegaly Digestive 0.927 0.83 – 1.04 0.18 354 3832 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.05 0.994 – 1.11 0.0784 1411 14399 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.882 0.825 – 0.943 0.000213 934 13659 exclusion phecode
580.1 Glomerulonephritis Genitourinary 0.829 0.765 – 0.898 4.91e-06 638 9308 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.04 0.77 – 1.4 0.801 40 672 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.95 0.753 – 1.2 0.662 82 1193 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.796 0.729 – 0.869 3.97e-07 531 7742 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.07 0.947 – 1.22 0.268 262 4226 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.928 0.781 – 1.1 0.39 139 2212 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.94 0.794 – 1.11 0.473 144 2268 exclusion phecode
585 Renal failure Genitourinary 0.942 0.916 – 0.969 4.28e-05 5181 62619 exclusion phecode
585.1 Acute renal failure Genitourinary 0.963 0.93 – 0.996 0.0302 3560 40827 exclusion phecode
585.2 Renal failure NOS Genitourinary 0.973 0.912 – 1.04 0.418 1000 13191 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.879 0.835 – 0.926 1.34e-06 1533 23731 exclusion phecode
585.31 Renal dialysis Genitourinary 1 0.862 – 1.16 0.983 183 4427 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.03 0.994 – 1.08 0.0927 2709 30044 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.18 0.992 – 1.41 0.0607 136 1838 exclusion phecode
586.11 Small kidney Genitourinary 1.11 0.922 – 1.35 0.261 119 1589 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.05 0.984 – 1.12 0.146 1079 11303 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.12 0.859 – 1.46 0.402 52 727 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.07 0.995 – 1.16 0.0659 750 8190 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.03 0.855 – 1.23 0.774 117 3306 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 1.32 0.982 – 1.77 0.0659 45 882 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 0.883 0.7 – 1.11 0.294 77 1032 exclusion phecode
590 Pyelonephritis Genitourinary 1.05 0.988 – 1.12 0.109 1058 11470 exclusion phecode
591 Urinary tract infection Genitourinary 0.999 0.979 – 1.02 0.894 10338 108406 exclusion phecode
592 Cystitis and urethritis Genitourinary 0.989 0.949 – 1.03 0.582 2531 25781 exclusion phecode
592.1 Cystitis Genitourinary 0.991 0.951 – 1.03 0.684 2470 25206 exclusion phecode
592.11 Acute cystitis Genitourinary 1.04 0.853 – 1.26 0.727 112 1227 exclusion phecode
592.12 Chronic cystitis Genitourinary 0.986 0.913 – 1.06 0.719 738 7748 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 0.884 0.771 – 1.01 0.0767 218 2107 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.04 0.875 – 1.23 0.667 146 1447 exclusion phecode
593 Hematuria Genitourinary 1.03 1.01 – 1.04 0.00333 14035 142638 exclusion phecode
594 Urinary calculus Genitourinary 1.11 1.08 – 1.14 4.28e-14 5644 57520 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.15 1.11 – 1.2 8.73e-13 2773 28502 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.06 0.984 – 1.15 0.119 685 7099 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.11 1.06 – 1.16 2.79e-06 2139 21817 exclusion phecode
594.8 Renal colic Genitourinary 1.09 1.03 – 1.14 0.000847 1820 18504 exclusion phecode
595 Hydronephrosis Genitourinary 1.06 1.01 – 1.11 0.0302 1614 17343 exclusion phecode
596 Other disorders of bladder Genitourinary 0.997 0.975 – 1.02 0.817 8502 87422 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.02 0.971 – 1.07 0.44 1790 18185 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 0.996 0.942 – 1.05 0.876 1371 14531 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.03 0.994 – 1.07 0.103 3368 34678 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.04 0.998 – 1.08 0.0657 2882 29551 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.28 0.992 – 1.66 0.0571 62 686 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 0.995 0.959 – 1.03 0.797 3097 31469 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.07 0.938 – 1.22 0.316 240 2718 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.998 – 1.03 0.0774 15768 161194 exclusion phecode
599.1 Urinary obstruction Genitourinary 1.01 0.848 – 1.21 0.893 133 1488 exclusion phecode
599.2 Retention of urine Genitourinary 1.02 0.993 – 1.05 0.148 5855 60734 exclusion phecode
599.3 Dysuria Genitourinary 0.981 0.921 – 1.05 0.563 1038 10612 exclusion phecode
599.4 Urinary incontinence Genitourinary 1 0.98 – 1.03 0.747 7253 74032 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.03 0.99 – 1.06 0.159 3506 35784 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.05 0.852 – 1.3 0.639 91 950 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.23 0.927 – 1.63 0.153 54 541 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1.01 0.96 – 1.06 0.723 1687 17229 exclusion phecode
600 Hyperplasia of prostate Genitourinary 1 0.983 – 1.02 0.734 10155 81642 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 0.997 0.951 – 1.05 0.904 1906 19341 exclusion phecode
601.1 Prostatitis Genitourinary 0.999 0.947 – 1.06 0.98 1436 14541 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.962 0.837 – 1.11 0.588 215 2190 exclusion phecode
601.12 Chronic prostatitis Genitourinary 0.995 0.927 – 1.07 0.883 838 8448 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 1.08 0.819 – 1.41 0.601 58 548 exclusion phecode
601.4 Balanoposthitis Genitourinary 1.05 0.926 – 1.19 0.444 269 2665 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.948 0.837 – 1.07 0.402 269 2799 exclusion phecode
602 Other disorders of prostate Genitourinary 1.02 0.965 – 1.08 0.449 1222 12370 exclusion phecode
603 Other disorders of testis Genitourinary 0.952 0.909 – 0.997 0.0374 1967 20065 exclusion phecode
603.1 Hydrocele Genitourinary 0.922 0.869 – 0.977 0.00648 1233 12487 exclusion phecode
604 Disorders of penis Genitourinary 0.996 0.959 – 1.03 0.828 3004 30595 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.977 0.937 – 1.02 0.265 2480 25337 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.977 0.862 – 1.11 0.717 260 2622 exclusion phecode
608 Other disorders of male genital organs Genitourinary 0.984 0.945 – 1.02 0.424 2608 26319 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.09 0.939 – 1.26 0.265 194 1994 exclusion phecode
609.1 Infertility, male Genitourinary 1.02 0.778 – 1.34 0.885 58 595 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 1.09 0.923 – 1.28 0.314 153 1584 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.985 0.941 – 1.03 0.51 2075 20697 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.969 0.9 – 1.04 0.416 780 7714 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 0.993 0.873 – 1.13 0.919 247 2560 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 0.988 0.866 – 1.13 0.855 243 2524 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.986 0.928 – 1.05 0.639 1173 11563 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.01 0.926 – 1.1 0.858 587 5768 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.983 0.928 – 1.04 0.571 1297 13133 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.827 0.605 – 1.13 0.232 50 474 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.988 0.931 – 1.05 0.675 1252 12701 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.02 0.949 – 1.1 0.553 760 7576 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.03 0.954 – 1.11 0.457 732 7255 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 1.09 0.835 – 1.43 0.516 60 597 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 1.03 0.978 – 1.1 0.233 1360 13776 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.01 0.925 – 1.1 0.879 596 6014 exclusion phecode
613.5 Mastodynia Genitourinary 0.767 0.585 – 1.01 0.0549 61 645 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 1.05 0.96 – 1.14 0.291 574 5820 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1.11 0.974 – 1.26 0.118 271 2733 exclusion phecode
613.9 Breast disorder NOS Genitourinary 1.06 0.906 – 1.24 0.474 178 1694 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.02 0.987 – 1.05 0.261 4727 47749 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.02 0.973 – 1.07 0.439 2077 21185 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.01 0.931 – 1.09 0.849 686 6913 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.82 0.618 – 1.09 0.172 49 507 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.05 0.936 – 1.17 0.428 351 3519 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.939 0.832 – 1.06 0.301 293 2907 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.938 0.815 – 1.08 0.37 221 2310 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.01 0.966 – 1.06 0.665 2170 21831 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.01 0.95 – 1.08 0.708 1082 11113 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.886 0.796 – 0.985 0.0254 371 3603 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.1 1.02 – 1.2 0.0196 624 6343 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.05 0.918 – 1.21 0.459 233 2295 exclusion phecode
615 Endometriosis Genitourinary 0.973 0.939 – 1.01 0.14 3332 33659 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 0.998 0.873 – 1.14 0.981 241 2540 exclusion phecode
618 Genital prolapse Genitourinary 1.03 1.01 – 1.05 0.00804 9590 97663 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 1.04 1.01 – 1.06 0.0112 6081 61745 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.02 0.988 – 1.05 0.217 4382 45038 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.92 0.829 – 1.02 0.111 412 4240 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.09 0.999 – 1.19 0.0524 553 5603 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1 0.981 – 1.03 0.698 7223 72858 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.01 0.927 – 1.1 0.838 600 6075 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 1.02 0.98 – 1.06 0.344 2782 27788 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.986 0.945 – 1.03 0.522 2360 23751 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.04 0.988 – 1.1 0.131 1462 14742 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.966 0.907 – 1.03 0.268 1103 11212 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1.22 0.938 – 1.58 0.14 61 594 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.976 0.912 – 1.05 0.488 943 9469 exclusion phecode
622 Polyp of female genital organs Genitourinary 1 0.979 – 1.02 0.964 8729 87428 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.988 0.963 – 1.01 0.377 6556 65656 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 1 0.965 – 1.04 0.855 2868 28589 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.01 0.952 – 1.08 0.66 1087 10607 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.976 0.901 – 1.06 0.546 660 6593 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 1.02 0.879 – 1.18 0.825 198 1961 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 1.01 0.907 – 1.13 0.85 361 3657 exclusion phecode
624.9 stress incontinence, female Genitourinary 1.01 0.977 – 1.04 0.679 4862 48871 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.972 0.932 – 1.01 0.196 2388 24005 exclusion phecode
625.1 Dyspareunia Genitourinary 0.984 0.921 – 1.05 0.628 1009 9914 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.993 0.975 – 1.01 0.471 13391 96339 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.994 0.975 – 1.01 0.565 11683 92053 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.775 0.625 – 0.96 0.0197 92 915 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 0.989 0.966 – 1.01 0.343 8027 76809 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.984 0.935 – 1.04 0.551 1638 16561 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 1.01 0.972 – 1.05 0.636 3151 31883 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.931 0.882 – 0.983 0.00928 1474 14952 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.961 0.804 – 1.15 0.66 136 1320 exclusion phecode
626.8 Infertility, female Genitourinary 1.02 0.96 – 1.09 0.495 1137 11393 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.988 0.966 – 1.01 0.282 8598 86729 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 0.984 0.96 – 1.01 0.179 7484 75444 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.887 0.75 – 1.05 0.163 146 1512 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.01 0.94 – 1.08 0.851 928 9259 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1 0.879 – 1.14 0.995 253 2583 exclusion phecode
628 Ovarian cyst Genitourinary 0.978 0.946 – 1.01 0.193 3937 39691 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.01 0.98 – 1.04 0.478 4432 30471 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.948 0.887 – 1.01 0.117 951 9438 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1 0.886 – 1.14 0.949 280 2759 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.972 0.923 – 1.02 0.272 1667 14557 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.965 0.894 – 1.04 0.364 736 7246 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.964 0.905 – 1.03 0.258 1067 10314 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.963 0.918 – 1.01 0.113 1959 16700 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.936 0.855 – 1.02 0.147 525 5136 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.97 0.907 – 1.04 0.387 921 8967 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 1.04 0.801 – 1.36 0.751 59 573 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.05 0.98 – 1.12 0.168 927 9258 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.14 1 – 1.29 0.0502 259 2546 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.11 0.951 – 1.3 0.187 185 1791 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.994 0.828 – 1.19 0.953 135 1236 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.06 0.998 – 1.13 0.0573 1073 10435 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.948 0.904 – 0.995 0.0316 1850 17482 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.893 0.677 – 1.18 0.424 51 569 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.904 0.787 – 1.04 0.152 225 2309 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.922 0.746 – 1.14 0.448 93 962 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.911 0.769 – 1.08 0.277 145 1576 exclusion phecode
650 Normal delivery Pregnancy Complications 1 0.952 – 1.05 0.959 1627 15966 exclusion phecode
651 Multiple gestation Pregnancy Complications 1.04 0.919 – 1.17 0.556 298 2887 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.965 0.914 – 1.02 0.196 1461 13926 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.04 0.978 – 1.1 0.219 1165 11472 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 0.741 0.561 – 0.979 0.0349 58 613 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1 0.965 – 1.04 0.998 3649 24708 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.947 0.76 – 1.18 0.628 89 911 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.99 0.944 – 1.04 0.672 1913 15419 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 1.01 0.918 – 1.11 0.82 450 4469 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.99 0.958 – 1.02 0.535 4508 24659 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.02 0.976 – 1.07 0.366 2141 17778 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.08 0.906 – 1.29 0.387 134 1393 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.07 0.93 – 1.22 0.355 225 2188 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.07 0.803 – 1.43 0.643 51 526 exclusion phecode
679 Complications of in utero procedures Dermatologic 0.826 0.609 – 1.12 0.218 40 454 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 0.998 0.972 – 1.02 0.859 6118 64272 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.06 0.96 – 1.16 0.265 471 4987 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.05 0.95 – 1.16 0.345 442 4579 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.988 0.959 – 1.02 0.436 4661 49205 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.987 0.958 – 1.02 0.399 4664 49260 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.985 0.955 – 1.01 0.314 4624 48875 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.1 1 – 1.21 0.0405 508 5268 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 0.985 0.927 – 1.05 0.622 1127 11845 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.1 1.05 – 1.15 9.39e-05 1960 20306 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.1 1.01 – 1.21 0.0341 518 5299 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.01 0.902 – 1.14 0.817 306 3180 exclusion phecode
687 Symptoms affecting skin Dermatologic 1.04 0.945 – 1.14 0.42 473 4846 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.956 0.911 – 1 0.0654 1833 18868 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 0.956 0.838 – 1.09 0.509 239 2477 exclusion phecode
687.3 Changes in skin texture Dermatologic 1.05 0.851 – 1.31 0.629 92 939 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 0.991 0.951 – 1.03 0.664 2489 25336 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.03 1 – 1.06 0.0533 4946 50482 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.974 0.749 – 1.27 0.843 61 643 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.945 0.689 – 1.3 0.726 43 482 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.828 0.678 – 1.01 0.0648 106 1042 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 1.02 0.954 – 1.1 0.524 855 8502 exclusion phecode
694.1 Vitiligo Dermatologic 1.22 0.927 – 1.61 0.155 54 522 exclusion phecode
694.2 Other dyschromia Dermatologic 0.993 0.918 – 1.07 0.863 683 6728 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.12 0.913 – 1.37 0.278 98 1039 exclusion phecode
695 Erythematous conditions Dermatologic 1.06 1.01 – 1.11 0.0101 2021 20675 exclusion phecode
695.1 Toxic erythema Dermatologic 1.05 0.852 – 1.28 0.672 94 963 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.17 0.966 – 1.41 0.109 119 1185 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 1 0.755 – 1.33 0.991 51 494 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.29 0.99 – 1.68 0.0596 62 627 exclusion phecode
695.3 Rosacea Dermatologic 1.16 1.03 – 1.32 0.0179 278 2762 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.1 0.982 – 1.23 0.0988 332 3502 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.06 0.883 – 1.28 0.515 109 1091 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.18 1.04 – 1.34 0.00894 273 2909 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 1.01 0.934 – 1.1 0.757 653 6699 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 0.99 0.861 – 1.14 0.882 206 2059 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.872 0.682 – 1.12 0.276 69 664 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.06 0.953 – 1.17 0.293 397 4122 exclusion phecode
696 Psoriasis and related disorders Dermatologic 1 0.957 – 1.05 0.903 1917 19977 exclusion phecode
696.4 Psoriasis Dermatologic 1 0.958 – 1.05 0.848 1873 19512 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.999 0.946 – 1.06 0.978 1434 14946 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 1.03 0.95 – 1.12 0.44 605 6215 exclusion phecode
697 Sarcoidosis Dermatologic 0.95 0.863 – 1.04 0.288 472 4745 exclusion phecode
698 Pruritus and related conditions Dermatologic 1.07 0.991 – 1.16 0.0822 667 6823 exclusion phecode
700 Corns and callosities Dermatologic 1.01 0.878 – 1.16 0.915 232 2523 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.02 0.991 – 1.06 0.15 4029 40667 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 1.06 0.842 – 1.33 0.627 78 771 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.06 1.02 – 1.11 0.00694 2031 20380 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 1.06 0.804 – 1.39 0.692 52 523 exclusion phecode
701.4 Keloid scar Dermatologic 1.04 0.894 – 1.21 0.613 178 1881 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1 0.903 – 1.11 0.948 397 3970 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 0.904 0.735 – 1.11 0.335 89 894 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.01 0.979 – 1.04 0.553 4772 47861 exclusion phecode
702.1 Actinic keratosis Dermatologic 1.03 0.986 – 1.08 0.178 2250 22576 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.997 0.958 – 1.04 0.894 2696 26994 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.05 0.928 – 1.18 0.456 298 3128 exclusion phecode
703.1 Ingrowing nail Dermatologic 1.02 0.954 – 1.1 0.528 856 8610 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 1.04 1.01 – 1.07 0.0199 4642 46649 exclusion phecode
704.1 Alopecia Dermatologic 1.32 1.08 – 1.62 0.00808 106 1092 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.931 0.716 – 1.21 0.597 66 682 exclusion phecode
705 Disorders of sweat glands Dermatologic 0.984 0.844 – 1.15 0.842 188 1964 exclusion phecode
705.3 Hidradenitis Dermatologic 0.967 0.813 – 1.15 0.705 151 1596 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.09 0.995 – 1.19 0.0631 514 5314 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1.01 0.982 – 1.03 0.639 7285 73270 exclusion phecode
706.1 Acne Dermatologic 1.52 1.17 – 1.96 0.00149 66 674 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1 0.977 – 1.02 0.986 7710 77410 exclusion phecode
707 Chronic ulcer of skin Dermatologic 0.97 0.921 – 1.02 0.251 1520 17615 exclusion phecode
707.1 Decubitus ulcer Dermatologic 0.981 0.909 – 1.06 0.613 717 8085 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.932 0.897 – 0.968 0.000297 2900 29790 exclusion phecode
709.2 Sicca syndrome Dermatologic 0.926 0.836 – 1.03 0.139 414 4244 exclusion phecode
709.3 Systemic sclerosis Dermatologic 0.906 0.759 – 1.08 0.276 137 1519 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.02 0.787 – 1.33 0.863 52 546 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.94 0.9 – 0.98 0.00411 2316 23696 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.02 0.924 – 1.12 0.755 482 5410 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.03 0.931 – 1.13 0.606 450 5008 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.05 0.891 – 1.23 0.58 163 1742 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.01 0.901 – 1.14 0.837 315 3600 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 1.03 0.922 – 1.15 0.612 356 3775 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 0.992 0.877 – 1.12 0.904 283 2957 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 0.789 0.609 – 1.02 0.0726 68 728 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.01 0.824 – 1.23 0.943 103 1335 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.08 0.791 – 1.46 0.64 40 604 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.02 0.987 – 1.05 0.228 3970 41787 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.02 0.983 – 1.05 0.309 3582 37824 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.01 0.953 – 1.06 0.811 1400 14618 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.02 0.829 – 1.25 0.854 90 978 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.02 0.936 – 1.12 0.625 519 5592 exclusion phecode
716 Other arthropathies Musculoskeletal 1 0.989 – 1.01 0.891 32361 233715 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.03 0.988 – 1.07 0.184 2955 30409 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 1 0.984 – 1.02 0.817 13572 137115 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 0.999 0.988 – 1.01 0.923 31061 230972 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.02 0.957 – 1.09 0.507 977 9967 exclusion phecode
720 Spinal stenosis Musculoskeletal 0.962 0.928 – 0.998 0.0391 3216 32603 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 0.996 0.971 – 1.02 0.773 6636 68132 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1 0.969 – 1.03 0.986 4313 43877 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.02 0.867 – 1.2 0.825 165 1666 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 0.908 0.803 – 1.03 0.123 286 3087 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 0.985 0.963 – 1.01 0.215 7796 79052 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.02 0.925 – 1.12 0.702 451 4531 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.92 0.882 – 0.96 0.000109 2418 24782 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 0.789 0.605 – 1.03 0.0811 59 603 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.985 0.953 – 1.02 0.389 3841 38828 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.01 0.917 – 1.11 0.845 454 4593 exclusion phecode
723.1 Torticollis Musculoskeletal 1.11 0.911 – 1.36 0.296 93 943 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 0.998 0.95 – 1.05 0.924 1759 18047 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1.02 0.912 – 1.14 0.752 352 3413 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 1.04 0.935 – 1.17 0.445 355 3441 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 0.867 0.655 – 1.15 0.318 53 557 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1 0.946 – 1.06 0.993 1378 14329 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.988 0.97 – 1.01 0.182 12733 128897 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.979 0.957 – 1 0.0719 8274 84008 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.988 0.873 – 1.12 0.852 272 2888 exclusion phecode
726.3 Bursitis Musculoskeletal 0.987 0.917 – 1.06 0.734 766 7797 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1 0.974 – 1.03 0.984 6275 64192 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.998 0.957 – 1.04 0.94 2337 24044 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.98 0.792 – 1.21 0.856 93 936 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.993 0.955 – 1.03 0.747 2662 26905 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.948 0.865 – 1.04 0.258 503 5065 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.965 0.857 – 1.09 0.565 305 3159 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.06 0.874 – 1.28 0.569 121 1260 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.98 0.945 – 1.02 0.261 3322 33245 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.02 0.921 – 1.14 0.659 371 3645 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.973 0.94 – 1.01 0.133 3451 34366 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.982 0.946 – 1.02 0.324 3157 31485 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 0.979 0.951 – 1.01 0.148 5125 52594 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.986 0.917 – 1.06 0.699 832 8478 exclusion phecode
729.3 Panniculitis Musculoskeletal 1.07 0.868 – 1.33 0.513 89 897 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.04 0.904 – 1.19 0.605 221 2377 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.06 0.917 – 1.22 0.443 208 2259 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.992 0.897 – 1.1 0.877 411 4122 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.03 0.881 – 1.2 0.729 179 1809 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.03 0.772 – 1.36 0.863 49 510 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.02 0.966 – 1.07 0.499 1484 15373 exclusion phecode
733.2 Cyst of bone Musculoskeletal 0.941 0.828 – 1.07 0.347 263 2713 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.11 1.01 – 1.23 0.032 454 4697 exclusion phecode
733.6 Costochondritis Musculoskeletal 0.842 0.689 – 1.03 0.0906 104 1092 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.957 0.898 – 1.02 0.168 1060 10846 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.06 0.874 – 1.28 0.559 113 1059 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1.01 0.983 – 1.03 0.619 8112 81555 exclusion phecode
735.1 Flat foot Musculoskeletal 0.989 0.84 – 1.16 0.895 160 1649 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 1.02 0.987 – 1.05 0.239 4267 43282 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.01 0.961 – 1.06 0.652 1620 16450 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 1 0.946 – 1.06 0.949 1332 13388 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.01 0.982 – 1.04 0.512 5624 56022 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1 0.949 – 1.06 0.935 1388 14278 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 0.931 0.814 – 1.07 0.3 219 2167 exclusion phecode
737 Curvature of spine Musculoskeletal 0.927 0.865 – 0.993 0.0317 898 9643 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.924 0.86 – 0.992 0.0297 838 9053 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.98 0.931 – 1.03 0.428 1637 16527 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.967 0.913 – 1.02 0.249 1306 13040 exclusion phecode
739 Contracture of joint Musculoskeletal 0.962 0.869 – 1.06 0.452 428 4299 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1 0.99 – 1.02 0.649 23859 203139 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.999 0.982 – 1.02 0.924 15069 148508 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.995 0.972 – 1.02 0.647 7825 78780 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.02 0.903 – 1.15 0.773 280 3035 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.997 0.907 – 1.1 0.947 488 5164 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1 0.98 – 1.02 0.994 10506 106995 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.02 0.979 – 1.05 0.407 3084 31423 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 1.12 0.896 – 1.39 0.328 90 910 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 0.968 0.885 – 1.06 0.471 540 5382 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 1.12 0.931 – 1.34 0.235 127 1353 exclusion phecode
741.4 Joint effusions Musculoskeletal 1.03 0.97 – 1.09 0.334 1204 12663 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 0.879 0.705 – 1.09 0.249 89 992 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.822 0.61 – 1.11 0.198 45 469 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.994 0.953 – 1.04 0.758 2481 25174 exclusion phecode
742.1 Loose body in joint Musculoskeletal 1 0.892 – 1.13 0.94 301 3000 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.849 0.676 – 1.07 0.157 80 843 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.03 0.933 – 1.13 0.565 441 4396 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.985 0.937 – 1.04 0.555 1734 17634 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.02 0.992 – 1.05 0.178 6099 64789 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.03 1 – 1.06 0.0524 5109 54673 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.03 1 – 1.07 0.037 4374 47171 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1.03 0.931 – 1.13 0.59 440 4669 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.05 0.944 – 1.16 0.393 410 4525 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.949 0.879 – 1.03 0.186 708 7116 exclusion phecode
745 Pain in joint Musculoskeletal 1 0.98 – 1.03 0.713 6830 69998 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.01 0.965 – 1.05 0.771 2397 24908 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.01 0.967 – 1.06 0.642 2254 23395 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.955 0.87 – 1.05 0.336 506 5139 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1 0.866 – 1.16 0.994 206 2122 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.03 0.977 – 1.08 0.281 1548 16256 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.932 0.78 – 1.11 0.439 137 1477 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.785 0.578 – 1.06 0.119 44 452 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.12 0.982 – 1.27 0.0915 263 2692 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.95 0.871 – 1.04 0.243 562 6062 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.967 0.857 – 1.09 0.589 285 2896 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.04 0.889 – 1.21 0.646 174 1693 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.964 0.852 – 1.09 0.561 275 3152 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.923 0.795 – 1.07 0.291 190 2000 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.02 0.808 – 1.3 0.851 74 1022 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.998 0.941 – 1.06 0.947 1218 13429 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.978 0.899 – 1.06 0.61 606 6012 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.986 0.887 – 1.1 0.799 381 3758 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.898 0.779 – 1.03 0.136 212 2069 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.02 0.936 – 1.1 0.715 614 7467 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.987 0.874 – 1.11 0.832 279 3766 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.02 0.896 – 1.15 0.802 267 2972 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.03 0.909 – 1.17 0.623 263 2886 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.09 0.941 – 1.26 0.256 204 2218 exclusion phecode
752.11 Spina bifida Congenital Anomalies 1.12 0.949 – 1.31 0.183 163 1829 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.869 0.668 – 1.13 0.298 61 697 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.942 0.779 – 1.14 0.537 115 1095 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.787 0.61 – 1.01 0.064 67 650 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.12 0.894 – 1.4 0.329 89 961 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.948 0.848 – 1.06 0.352 347 3694 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.01 0.861 – 1.17 0.946 176 1785 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.938 0.783 – 1.12 0.483 126 1384 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.959 0.768 – 1.2 0.713 82 895 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1 0.914 – 1.1 0.98 504 5142 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.04 0.808 – 1.33 0.78 69 707 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.977 0.881 – 1.08 0.666 376 3819 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.04 0.868 – 1.24 0.68 130 1473 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.16 0.873 – 1.53 0.313 51 703 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.918 0.787 – 1.07 0.275 178 1890 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.898 0.724 – 1.11 0.328 89 846 exclusion phecode
760 Back pain Symptoms 0.967 0.947 – 0.988 0.00198 9596 97455 exclusion phecode
761 Cervicalgia Symptoms 1.02 0.969 – 1.08 0.431 1517 15643 exclusion phecode
764 Sciatica Symptoms 1.01 0.966 – 1.06 0.654 2036 20748 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.958 0.897 – 1.02 0.208 1004 10213 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 0.945 0.864 – 1.03 0.214 540 5536 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.04 0.962 – 1.12 0.342 744 7592 exclusion phecode
771.1 Swelling of limb Symptoms 0.978 0.947 – 1.01 0.19 3940 40616 exclusion phecode
772 Symptoms of the muscles Symptoms 0.985 0.902 – 1.08 0.737 543 5833 exclusion phecode
773 Pain in limb Symptoms 0.969 0.942 – 0.997 0.0321 5267 54170 exclusion phecode
780 Hypothermia/Chills Symptoms 0.927 0.779 – 1.1 0.39 142 1538 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.01 0.956 – 1.06 0.803 1581 16472 exclusion phecode
782.3 Edema Symptoms 1.04 0.986 – 1.1 0.142 1335 14501 exclusion phecode
782.6 Pallor and flushing Symptoms 1.16 0.99 – 1.37 0.0658 152 1564 exclusion phecode
783 Fever of unknown origin Symptoms 0.996 0.961 – 1.03 0.823 3332 34539 exclusion phecode
785 Abdominal pain Symptoms 1 0.992 – 1.01 0.589 34441 265750 exclusion phecode
788 Syncope and collapse Symptoms 0.995 0.972 – 1.02 0.656 7852 80426 exclusion phecode
789 Nausea and vomiting Symptoms 0.999 0.979 – 1.02 0.951 9759 100814 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.05 0.874 – 1.27 0.59 127 1321 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.11 0.859 – 1.43 0.435 71 730 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.02 0.996 – 1.05 0.0906 5591 57759 exclusion phecode
791 Gangrene Symptoms 1.05 0.949 – 1.15 0.365 433 4977 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1.13 0.899 – 1.43 0.29 76 794 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.02 0.844 – 1.24 0.806 116 1164 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.07 0.975 – 1.18 0.153 487 4969 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.876 0.715 – 1.07 0.2 105 1044 exclusion phecode
797 Shock Symptoms 1.09 0.906 – 1.31 0.366 130 1384 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.02 0.822 – 1.26 0.887 89 914 exclusion phecode
798 Malaise and fatigue Symptoms 0.969 0.932 – 1.01 0.105 2862 29878 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 0.981 0.894 – 1.08 0.689 504 5100 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.02 0.989 – 1.04 0.256 5958 61543 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.03 0.974 – 1.08 0.32 1500 15783 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.03 0.871 – 1.22 0.722 149 1531 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.04 0.989 – 1.09 0.133 1862 19122 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.936 0.864 – 1.01 0.108 662 6832 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.02 0.969 – 1.06 0.533 1933 19437 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.03 0.978 – 1.08 0.272 1617 16177 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 0.974 0.896 – 1.06 0.539 593 6321 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 1 0.976 – 1.02 0.99 7069 72213 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1 0.946 – 1.06 0.999 1402 14732 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.99 0.959 – 1.02 0.513 4427 44943 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.996 0.941 – 1.05 0.884 1335 13755 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 1.01 0.973 – 1.05 0.59 2977 29712 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.974 0.917 – 1.03 0.396 1160 12087 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.03 0.956 – 1.12 0.408 680 6949 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.985 0.926 – 1.05 0.624 1129 11573 exclusion phecode
817 Concussion Injuries & Poisonings 1.03 0.898 – 1.18 0.681 225 2183 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.979 0.888 – 1.08 0.677 446 4639 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.997 0.957 – 1.04 0.866 2614 26698 exclusion phecode
823 Torus fracture Injuries & Poisonings 1.02 0.97 – 1.08 0.382 1434 14780 exclusion phecode
830 Dislocation Injuries & Poisonings 1.03 0.985 – 1.08 0.181 1873 18669 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 1.01 0.994 – 1.03 0.203 13611 135540 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 1.04 0.944 – 1.14 0.448 463 4699 exclusion phecode
840 Sprains and strains Injuries & Poisonings 1 0.907 – 1.11 0.963 429 4210 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.997 0.967 – 1.03 0.846 4462 46242 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.959 0.804 – 1.14 0.646 136 1393 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.09 0.986 – 1.21 0.0905 415 4404 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.03 0.972 – 1.08 0.359 1455 16476 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.935 0.877 – 0.996 0.0382 1027 10981 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.02 0.982 – 1.06 0.288 2651 27547 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.01 0.97 – 1.05 0.65 2709 28595 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.04 0.805 – 1.35 0.746 59 623 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.01 0.977 – 1.05 0.452 3050 31405 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.03 0.901 – 1.17 0.678 236 2421 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1.01 0.866 – 1.19 0.869 171 1762 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.01 0.969 – 1.05 0.66 2518 26039 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.02 0.883 – 1.19 0.754 191 1954 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.858 0.657 – 1.12 0.264 61 608 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.01 0.976 – 1.04 0.596 3651 36621 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1 0.755 – 1.33 0.984 47 482 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.991 0.793 – 1.24 0.936 84 825 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.23 1.04 – 1.46 0.0149 153 1571 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.04 0.943 – 1.15 0.434 442 4291 exclusion phecode
873 Broken tooth Injuries & Poisonings 1.22 1.05 – 1.42 0.00964 187 2009 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.08 0.912 – 1.29 0.365 135 1545 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.09 0.914 – 1.29 0.345 136 1409 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.01 0.95 – 1.08 0.731 1122 11780 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.01 0.978 – 1.05 0.508 3664 37859 exclusion phecode
916 Contusion Injuries & Poisonings 1 0.944 – 1.06 0.971 1218 12820 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 1.12 0.947 – 1.32 0.187 152 1570 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.07 0.957 – 1.19 0.238 344 3399 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 1.05 0.916 – 1.2 0.484 224 2212 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.971 0.925 – 1.02 0.239 1789 18495 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.03 0.892 – 1.18 0.703 206 1952 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.01 0.816 – 1.25 0.918 84 935 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.984 0.896 – 1.08 0.737 466 4849 exclusion phecode
947 Urticaria Injuries & Poisonings 0.999 0.889 – 1.12 0.987 324 3235 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.17 1.04 – 1.31 0.00774 339 3518 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.04 0.936 – 1.16 0.453 364 3760 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.02 0.892 – 1.18 0.736 220 2344 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.909 0.823 – 1 0.0574 425 4434 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 0.68 0.501 – 0.924 0.0136 46 497 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.845 0.66 – 1.08 0.181 65 674 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1 0.987 – 1.02 0.705 15403 157234 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1 0.984 – 1.02 0.864 13487 137920 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.07 0.961 – 1.2 0.215 343 3614 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.978 0.905 – 1.06 0.577 713 7389 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.943 0.838 – 1.06 0.329 302 3223 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 0.961 0.853 – 1.08 0.51 299 3162 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.05 0.901 – 1.23 0.526 182 1945 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.921 0.804 – 1.06 0.237 220 2509 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.917 0.799 – 1.05 0.22 213 2450 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.996 0.968 – 1.03 0.811 5173 52759 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.987 0.922 – 1.06 0.697 935 9799 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.08 0.973 – 1.2 0.148 407 4153 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.951 0.85 – 1.06 0.38 335 3565 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.13 1.02 – 1.24 0.0198 436 4494 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.02 0.931 – 1.12 0.65 486 5029 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.04 0.986 – 1.09 0.152 1637 17108 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.06 0.902 – 1.24 0.489 161 1684 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.967 0.847 – 1.1 0.623 226 2432 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.07 0.844 – 1.35 0.584 72 769 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 0.993 0.804 – 1.23 0.946 89 951 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.05 0.836 – 1.31 0.683 82 930 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.826 0.623 – 1.09 0.183 52 563 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.01 0.764 – 1.34 0.926 46 489 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.03 0.886 – 1.2 0.696 189 2029 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.03 0.941 – 1.12 0.562 581 6087 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.14 0.971 – 1.34 0.111 174 1778 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 0.785 0.598 – 1.03 0.0829 58 556 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.14 0.925 – 1.4 0.219 93 949 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 1.02 0.821 – 1.26 0.871 90 981 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.17 0.92 – 1.48 0.202 77 794 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 0.97 0.932 – 1.01 0.136 2640 27429 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.02 0.977 – 1.06 0.404 2530 26833 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.02 0.977 – 1.06 0.404 2530 26833 exclusion phecode
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