Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Estimated glomerular filtration rate based on cystatin C UK Biobank (UKB) PheWAS analysis

Estimated glomerular filtration rate based on cystatin C — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID exprsweb-egfr-cystatinc-ckdgen-1000genomes-discoverymeta-egfrcys-lassosum-ukb-20211120Legacy LASSOSUMlassosumLarge GWAS

Evaluation cohort: UK Biobank (UKB).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: study-defined normal-range subset.

For this ExPRS, the exclusion sensitivity scan keeps only the study-defined normal-range subset for Estimated glomerular filtration rate based on cystatin C before rerunning the PheWAS. The preserved release does not include numeric bounds for this trait. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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Signal overview

The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.

85 rows visible 16 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 0.986 0.965 – 1.01 0.198 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 1 0.962 – 1.04 0.969 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.01 0.935 – 1.1 0.733 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 0.962 0.899 – 1.03 0.271 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 0.989 0.764 – 1.28 0.936 55 550 all phecode
010 Tuberculosis Infectious Diseases 1.01 0.858 – 1.18 0.95 166 1659 all phecode
038 Septicemia Infectious Diseases 1 0.969 – 1.03 0.999 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.01 0.938 – 1.08 0.842 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.01 0.924 – 1.11 0.782 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 0.988 0.97 – 1.01 0.223 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 0.948 0.914 – 0.983 0.00396 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 0.986 0.938 – 1.04 0.597 1641 16433 all phecode
041.4 E. coli Infectious Diseases 0.964 0.927 – 1 0.0655 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 1.1 0.99 – 1.22 0.0767 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.24 0.998 – 1.55 0.0518 95 949 all phecode
054 Herpes simplex Infectious Diseases 0.973 0.848 – 1.12 0.701 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 1.02 0.939 – 1.11 0.606 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 1.09 0.85 – 1.4 0.494 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.03 0.871 – 1.23 0.703 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 0.959 0.844 – 1.09 0.527 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 1.08 0.953 – 1.23 0.22 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 1.05 0.951 – 1.16 0.331 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.927 0.788 – 1.09 0.361 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.947 0.789 – 1.14 0.557 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 1.01 0.946 – 1.08 0.769 1004 10036 all phecode
079 Viral infection Infectious Diseases 1.01 0.967 – 1.05 0.755 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 1.06 0.822 – 1.37 0.653 64 640 all phecode
080 Postoperative infection Infectious Diseases 0.985 0.955 – 1.02 0.324 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 0.961 0.923 – 1 0.0562 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.09 0.846 – 1.41 0.497 71 709 all phecode
1000 Burns Injuries & Poisonings 1.01 0.93 – 1.1 0.759 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 0.951 0.898 – 1.01 0.0905 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 0.996 0.969 – 1.02 0.767 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.01 0.901 – 1.14 0.829 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 0.973 0.922 – 1.03 0.306 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 1.02 0.898 – 1.16 0.746 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 0.963 0.851 – 1.09 0.554 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1 0.94 – 1.07 0.937 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 0.991 0.969 – 1.01 0.407 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 0.997 0.971 – 1.02 0.844 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.01 0.988 – 1.03 0.369 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 0.929 0.766 – 1.13 0.456 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 0.925 0.827 – 1.04 0.178 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.938 0.736 – 1.2 0.607 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 1.03 0.994 – 1.06 0.108 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 0.984 0.968 – 1 0.0497 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.05 0.925 – 1.19 0.46 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 1.04 0.919 – 1.18 0.521 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.956 0.758 – 1.21 0.704 74 756 all phecode
110.12 Althete's foot Infectious Diseases 1.11 0.935 – 1.33 0.228 141 1410 all phecode
112 Candidiasis Infectious Diseases 1.03 0.98 – 1.07 0.272 2126 21275 all phecode
117 Mycoses Infectious Diseases 0.993 0.879 – 1.12 0.905 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 0.939 0.803 – 1.1 0.432 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 1.03 0.823 – 1.29 0.804 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 1.03 0.811 – 1.32 0.784 69 689 all phecode
134 Helminthiases Infectious Diseases 0.953 0.798 – 1.14 0.598 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 0.96 0.788 – 1.17 0.687 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.948 0.823 – 1.09 0.454 205 2050 all phecode
145 Cancer of mouth Neoplasms 1.01 0.934 – 1.1 0.747 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 1.06 0.945 – 1.2 0.311 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 0.921 0.756 – 1.12 0.418 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 0.944 0.718 – 1.24 0.679 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.13 1.04 – 1.23 0.00545 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 1.16 1.01 – 1.33 0.0326 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 1.07 0.946 – 1.22 0.271 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 1.15 0.875 – 1.52 0.314 57 570 all phecode
150 Cancer of esophagus Neoplasms 1.09 1.01 – 1.17 0.0313 762 7630 all phecode
151 Cancer of stomach Neoplasms 1.02 0.938 – 1.11 0.614 569 5696 all phecode
153 Colorectal cancer Neoplasms 1.01 0.98 – 1.04 0.503 4580 45799 all phecode
153.2 Colon cancer Neoplasms 1 0.966 – 1.04 0.891 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.04 0.991 – 1.08 0.118 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.03 0.926 – 1.14 0.622 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.04 0.885 – 1.22 0.634 158 1580 all phecode
157 Pancreatic cancer Neoplasms 1.06 0.976 – 1.15 0.17 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.999 0.938 – 1.06 0.97 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.03 0.999 – 1.06 0.0618 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.995 0.86 – 1.15 0.944 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.07 0.928 – 1.24 0.337 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1 0.862 – 1.16 0.997 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 0.84 0.654 – 1.08 0.174 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 1 0.963 – 1.04 0.966 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 0.977 0.936 – 1.02 0.295 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.942 0.854 – 1.04 0.241 437 4364 all phecode
170.1 Bone cancer Neoplasms 0.818 0.687 – 0.973 0.0235 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 0.992 0.884 – 1.11 0.889 331 3303 all phecode
172 Skin cancer Neoplasms 1.01 0.99 – 1.03 0.414 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.04 0.996 – 1.08 0.079 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 1.04 0.995 – 1.08 0.0843 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1.01 0.987 – 1.03 0.54 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 0.947 0.876 – 1.02 0.177 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.09 0.93 – 1.27 0.291 181 1818 all phecode
174 Breast cancer Neoplasms 0.999 0.981 – 1.02 0.917 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 0.999 0.981 – 1.02 0.934 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1 0.985 – 1.02 0.71 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.964 0.802 – 1.16 0.698 115 1148 all phecode
175 Acquired absence of breast Neoplasms 1 0.959 – 1.04 0.99 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 1.03 0.982 – 1.07 0.237 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 1.02 0.9 – 1.16 0.762 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.05 0.998 – 1.09 0.0601 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 1.03 0.976 – 1.1 0.252 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 0.991 0.938 – 1.05 0.758 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.977 0.915 – 1.04 0.498 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.974 0.911 – 1.04 0.438 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.09 0.964 – 1.23 0.171 305 3049 all phecode
185 Cancer of prostate Neoplasms 0.983 0.958 – 1.01 0.217 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 0.957 0.871 – 1.05 0.352 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.834 0.661 – 1.05 0.126 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 1.01 0.899 – 1.14 0.847 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.931 0.773 – 1.12 0.449 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.01 0.974 – 1.04 0.717 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.02 0.961 – 1.09 0.466 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.03 0.963 – 1.1 0.409 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.997 0.774 – 1.28 0.978 66 660 all phecode
189.2 Cancer of bladder Neoplasms 0.996 0.956 – 1.04 0.864 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1 0.957 – 1.05 0.963 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.04 0.879 – 1.23 0.645 144 1439 all phecode
190 Cancer of eye Neoplasms 1.17 0.997 – 1.38 0.0538 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.02 0.946 – 1.11 0.559 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1 0.917 – 1.09 0.995 566 5650 all phecode
191.11 Cancer of brain Neoplasms 0.991 0.906 – 1.08 0.838 525 5240 all phecode
193 Thyroid cancer Neoplasms 0.879 0.792 – 0.976 0.0159 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 1.17 0.947 – 1.46 0.142 95 949 all phecode
195 Cancer, suspected or other Neoplasms 1.01 0.997 – 1.03 0.121 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 1.02 0.999 – 1.03 0.0638 16267 159497 all phecode
197 Chemotherapy Neoplasms 0.992 0.978 – 1.01 0.243 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 1 0.981 – 1.02 0.843 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.993 0.965 – 1.02 0.614 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.03 0.982 – 1.07 0.249 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.995 0.945 – 1.05 0.864 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.01 0.966 – 1.05 0.796 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.04 0.965 – 1.11 0.329 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 0.969 0.928 – 1.01 0.159 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.16 0.994 – 1.36 0.0602 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 1.03 0.973 – 1.09 0.32 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 1.12 0.904 – 1.39 0.297 95 950 all phecode
200 Myeloproliferative disease Neoplasms 0.972 0.911 – 1.04 0.392 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 0.938 0.846 – 1.04 0.226 387 3867 all phecode
201 Hodgkin's disease Neoplasms 1.09 0.96 – 1.24 0.18 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.993 0.951 – 1.04 0.74 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.995 0.948 – 1.04 0.832 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 0.854 0.77 – 0.947 0.00268 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 0.958 0.882 – 1.04 0.318 581 5824 all phecode
204 Leukemia Neoplasms 1.03 0.974 – 1.08 0.34 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 1.05 0.964 – 1.15 0.254 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.09 0.815 – 1.47 0.551 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.06 0.969 – 1.17 0.194 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 0.996 0.906 – 1.1 0.937 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 1.01 0.9 – 1.13 0.907 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.945 0.799 – 1.12 0.507 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 1.07 0.977 – 1.17 0.144 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 1.01 0.995 – 1.02 0.19 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.05 0.978 – 1.12 0.19 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.967 0.94 – 0.994 0.0178 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.04 0.933 – 1.17 0.465 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.956 0.851 – 1.08 0.455 318 3187 all phecode
214 Lipoma Neoplasms 0.993 0.968 – 1.02 0.605 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.984 0.955 – 1.01 0.301 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.942 0.886 – 1 0.0519 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 0.992 0.969 – 1.02 0.517 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.994 0.916 – 1.08 0.876 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 0.989 0.91 – 1.07 0.787 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 0.999 0.978 – 1.02 0.895 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 1 0.981 – 1.02 0.887 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.06 0.952 – 1.19 0.276 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 1 0.948 – 1.06 0.966 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.14 0.985 – 1.31 0.0807 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 0.821 0.705 – 0.956 0.0112 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.899 0.772 – 1.05 0.172 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 0.902 0.758 – 1.07 0.245 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.863 0.684 – 1.09 0.215 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.08 1 – 1.16 0.0414 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.07 0.991 – 1.15 0.0853 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.3 0.965 – 1.74 0.0846 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.09 0.958 – 1.24 0.192 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.975 0.91 – 1.04 0.476 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1 0.866 – 1.16 0.955 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.916 0.826 – 1.02 0.096 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.993 0.884 – 1.12 0.907 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.02 0.972 – 1.08 0.372 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.959 0.92 – 1 0.0492 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.983 0.905 – 1.07 0.692 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.05 0.986 – 1.12 0.128 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.962 0.875 – 1.06 0.43 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.11 1.02 – 1.2 0.0124 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.999 0.952 – 1.05 0.955 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 1.05 0.956 – 1.16 0.288 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.08 0.874 – 1.33 0.487 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.04 0.872 – 1.25 0.635 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 0.997 0.98 – 1.01 0.739 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.964 0.907 – 1.02 0.237 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.11 0.895 – 1.38 0.341 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1 0.983 – 1.02 0.937 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 1.1 0.97 – 1.24 0.139 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.1 0.953 – 1.26 0.2 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.09 0.944 – 1.25 0.246 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.03 0.933 – 1.15 0.518 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 1.01 0.991 – 1.02 0.428 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.03 0.991 – 1.07 0.13 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.15 0.997 – 1.31 0.0546 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.08 0.859 – 1.35 0.526 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.998 0.91 – 1.1 0.971 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.04 0.888 – 1.22 0.625 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.01 0.993 – 1.02 0.258 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.89 0.733 – 1.08 0.243 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.89 0.774 – 1.02 0.0987 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.99 0.928 – 1.06 0.771 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1 0.914 – 1.1 0.973 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 1.05 0.966 – 1.13 0.262 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.02 0.896 – 1.15 0.792 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.05 0.945 – 1.16 0.375 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.12 0.927 – 1.36 0.24 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.964 0.867 – 1.07 0.506 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1 0.948 – 1.06 0.924 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.08 1.01 – 1.16 0.0304 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.965 0.901 – 1.03 0.319 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.973 0.904 – 1.05 0.458 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.897 0.76 – 1.06 0.201 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.983 0.908 – 1.06 0.664 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.989 0.853 – 1.15 0.88 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.868 0.715 – 1.05 0.152 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.01 0.891 – 1.15 0.851 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.24 0.991 – 1.56 0.0597 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.934 0.798 – 1.09 0.395 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 1.01 0.927 – 1.09 0.875 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.995 0.854 – 1.16 0.947 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.06 0.864 – 1.31 0.568 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.904 0.72 – 1.14 0.386 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.968 0.869 – 1.08 0.553 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.968 0.868 – 1.08 0.552 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.01 0.888 – 1.16 0.827 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.03 0.893 – 1.19 0.675 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 0.913 0.781 – 1.07 0.253 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.919 0.781 – 1.08 0.306 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.985 0.81 – 1.2 0.876 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 0.974 0.824 – 1.15 0.761 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.04 0.9 – 1.2 0.6 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 1.02 0.77 – 1.36 0.871 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 1.02 0.952 – 1.1 0.539 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 1.03 0.967 – 1.09 0.399 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.02 0.947 – 1.1 0.586 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.995 0.903 – 1.1 0.918 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.923 0.738 – 1.15 0.478 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1 0.881 – 1.15 0.947 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 0.923 0.827 – 1.03 0.151 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.04 0.928 – 1.17 0.487 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.05 0.927 – 1.19 0.431 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.07 0.923 – 1.24 0.373 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 1.03 0.856 – 1.25 0.733 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.07 0.838 – 1.36 0.598 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.943 0.805 – 1.1 0.464 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.961 0.81 – 1.14 0.644 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.01 0.998 – 1.02 0.114 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.01 0.998 – 1.02 0.108 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.01 0.996 – 1.02 0.18 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.953 0.73 – 1.25 0.726 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.02 0.867 – 1.19 0.842 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.97 0.844 – 1.11 0.664 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.989 0.956 – 1.02 0.53 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 1 0.968 – 1.04 0.817 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.921 0.759 – 1.12 0.405 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.931 0.858 – 1.01 0.0881 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.922 0.846 – 1 0.0649 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.952 0.911 – 0.995 0.0289 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 0.972 0.897 – 1.05 0.476 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 0.905 0.816 – 1 0.0579 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.944 0.89 – 1 0.0542 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.919 0.785 – 1.08 0.296 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 0.994 0.97 – 1.02 0.6 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 0.975 0.944 – 1.01 0.118 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.906 0.795 – 1.03 0.137 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1 0.954 – 1.05 0.956 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 0.978 0.916 – 1.04 0.507 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 0.95 0.9 – 1 0.06 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.04 0.974 – 1.1 0.264 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 1.02 0.957 – 1.09 0.54 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 1.13 0.919 – 1.38 0.248 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.01 0.975 – 1.05 0.5 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 0.996 0.905 – 1.1 0.933 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 1.05 0.873 – 1.26 0.619 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.01 0.942 – 1.08 0.805 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.05 0.944 – 1.17 0.366 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.961 0.84 – 1.1 0.56 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.986 0.733 – 1.33 0.926 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.991 0.972 – 1.01 0.388 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 0.989 0.969 – 1.01 0.265 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 1.12 0.903 – 1.4 0.298 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.92 0.723 – 1.17 0.503 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.914 0.805 – 1.04 0.164 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 0.91 0.795 – 1.04 0.17 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.84 0.712 – 0.991 0.0386 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 0.923 0.81 – 1.05 0.227 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 0.999 0.976 – 1.02 0.94 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1 0.977 – 1.03 0.919 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.962 0.876 – 1.06 0.427 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 0.965 0.907 – 1.03 0.249 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 0.967 0.908 – 1.03 0.294 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 0.98 0.909 – 1.06 0.591 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.916 0.785 – 1.07 0.259 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 0.954 0.82 – 1.11 0.543 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 0.897 0.685 – 1.18 0.43 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 0.974 0.83 – 1.14 0.747 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 1 0.768 – 1.32 0.972 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.927 0.749 – 1.15 0.481 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 0.911 0.769 – 1.08 0.278 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.973 0.799 – 1.19 0.788 103 1059 all phecode
284 Aplastic anemia Hematopoietic 0.938 0.852 – 1.03 0.186 435 4357 all phecode
285 Other anemias Hematopoietic 1 0.982 – 1.02 0.93 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.03 0.904 – 1.16 0.699 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 1 0.927 – 1.08 0.975 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.973 0.882 – 1.07 0.591 414 4147 all phecode
286 Coagulation defects Hematopoietic 1.04 0.971 – 1.11 0.265 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 1.07 0.971 – 1.19 0.167 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 1.14 0.912 – 1.42 0.252 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.08 0.958 – 1.23 0.2 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.05 0.813 – 1.34 0.729 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.961 0.774 – 1.19 0.715 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.02 0.917 – 1.13 0.719 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.981 0.932 – 1.03 0.454 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.917 0.77 – 1.09 0.333 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 0.859 0.662 – 1.11 0.251 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 0.994 0.943 – 1.05 0.809 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.1 0.995 – 1.22 0.0612 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.2 0.934 – 1.54 0.154 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 0.998 0.966 – 1.03 0.925 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 1.01 0.975 – 1.05 0.562 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 1.01 0.975 – 1.05 0.562 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 0.859 0.683 – 1.08 0.191 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.02 0.947 – 1.09 0.646 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.09 0.966 – 1.23 0.161 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 0.981 0.943 – 1.02 0.359 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 1.04 0.949 – 1.14 0.409 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 0.989 0.877 – 1.12 0.859 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 0.888 0.721 – 1.09 0.265 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.992 0.946 – 1.04 0.723 1929 19281 all phecode
290.1 Dementias Mental Disorders 1.01 0.947 – 1.08 0.732 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 0.967 0.876 – 1.07 0.505 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 1.04 0.901 – 1.21 0.573 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.01 0.933 – 1.1 0.776 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.932 0.74 – 1.17 0.55 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1.04 0.966 – 1.12 0.307 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.06 0.881 – 1.27 0.542 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.04 0.918 – 1.18 0.546 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 1 0.909 – 1.11 0.96 436 4376 all phecode
292 Neurological disorders Mental Disorders 0.965 0.937 – 0.995 0.0202 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.982 0.933 – 1.03 0.5 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 1.02 0.875 – 1.18 0.819 190 1907 all phecode
292.3 Memory loss Mental Disorders 0.991 0.918 – 1.07 0.829 696 6978 all phecode
292.4 Altered mental status Mental Disorders 0.956 0.916 – 0.999 0.0427 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 0.998 0.889 – 1.12 0.97 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 0.971 0.929 – 1.01 0.187 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.05 0.981 – 1.13 0.159 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.02 0.952 – 1.1 0.532 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 1.02 0.933 – 1.11 0.706 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 0.992 0.851 – 1.16 0.915 178 1780 all phecode
295.3 Psychosis Mental Disorders 1.1 0.933 – 1.29 0.257 169 1710 all phecode
296 Mood disorders Mental Disorders 0.981 0.963 – 0.999 0.038 12372 123822 all phecode
296.1 Bipolar Mental Disorders 0.99 0.93 – 1.05 0.75 1059 10599 all phecode
296.2 Depression Mental Disorders 0.98 0.962 – 0.999 0.0375 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 0.973 0.873 – 1.08 0.619 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.08 0.959 – 1.21 0.209 311 3070 all phecode
300 Anxiety disorders Mental Disorders 0.996 0.971 – 1.02 0.725 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 0.998 0.972 – 1.02 0.857 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1.02 0.861 – 1.2 0.842 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.987 0.914 – 1.07 0.739 707 7065 all phecode
300.13 Phobia Mental Disorders 1.03 0.939 – 1.13 0.518 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.09 0.913 – 1.29 0.352 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 0.859 0.656 – 1.12 0.27 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 1.02 0.848 – 1.22 0.846 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.905 0.75 – 1.09 0.297 113 1129 all phecode
301 Personality disorders Mental Disorders 0.884 0.793 – 0.986 0.0273 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.987 0.819 – 1.19 0.894 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.959 0.848 – 1.08 0.501 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.975 0.886 – 1.07 0.596 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 1.04 0.925 – 1.16 0.542 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 0.929 0.776 – 1.11 0.418 123 1229 all phecode
304 Adjustment reaction Mental Disorders 1.02 0.901 – 1.15 0.785 293 2936 all phecode
305.2 Eating disorder Mental Disorders 1.09 0.88 – 1.36 0.422 90 900 all phecode
306 Other mental disorder Mental Disorders 0.996 0.984 – 1.01 0.576 28056 230087 all phecode
306.9 Tension headache Mental Disorders 1.01 0.9 – 1.14 0.825 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 1.15 0.909 – 1.46 0.24 76 770 all phecode
313.3 Autism Mental Disorders 0.94 0.721 – 1.22 0.645 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 0.995 0.892 – 1.11 0.931 351 3517 all phecode
315.1 Learning disorder Mental Disorders 1.1 0.928 – 1.3 0.275 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 1.07 0.854 – 1.33 0.575 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 0.997 0.969 – 1.02 0.813 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.16 0.888 – 1.51 0.279 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 0.996 0.978 – 1.01 0.67 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 0.995 0.973 – 1.02 0.629 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 1.03 0.959 – 1.11 0.416 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 1.01 0.999 – 1.03 0.0676 19359 185465 all phecode
320 Meningitis Neurological 1.05 0.947 – 1.15 0.376 444 4447 all phecode
323 Encephalitis Neurological 0.969 0.869 – 1.08 0.572 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 0.885 0.707 – 1.11 0.289 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 0.892 0.793 – 1 0.0558 292 2916 all phecode
327 Sleep disorders Neurological 0.907 0.856 – 0.961 0.00102 1164 11659 all phecode
327.3 Sleep apnea Neurological 1 0.97 – 1.03 0.997 4428 44318 all phecode
327.4 Insomnia Neurological 1.02 0.871 – 1.2 0.787 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 0.978 0.825 – 1.16 0.796 136 1390 all phecode
331 Other cerebral degenerations Neurological 1 0.941 – 1.06 0.992 1142 11416 all phecode
331.1 Hydrocephalus Neurological 0.995 0.907 – 1.09 0.923 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 0.961 0.871 – 1.06 0.423 430 4298 all phecode
332 Parkinson's disease Neurological 0.957 0.9 – 1.02 0.155 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.944 0.882 – 1.01 0.0938 894 8954 all phecode
333.1 Essential tremor Neurological 0.862 0.752 – 0.987 0.0315 216 2157 all phecode
333.2 Myoclonus Neurological 0.856 0.695 – 1.05 0.14 96 958 all phecode
333.4 Torsion dystonia Neurological 1.04 0.912 – 1.19 0.543 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 0.986 0.94 – 1.04 0.581 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 0.883 0.736 – 1.06 0.179 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 0.944 0.828 – 1.08 0.388 245 2446 all phecode
335 Multiple sclerosis Neurological 0.996 0.942 – 1.05 0.901 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 0.978 0.864 – 1.11 0.731 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 1.13 0.882 – 1.44 0.338 72 719 all phecode
338 Pain Neurological 0.902 0.84 – 0.969 0.00493 768 7692 all phecode
338.1 Acute pain Neurological 0.92 0.833 – 1.02 0.104 394 3937 all phecode
338.2 Chronic pain Neurological 0.917 0.828 – 1.02 0.096 380 3817 all phecode
339 Other headache syndromes Neurological 0.996 0.973 – 1.02 0.716 7819 78241 all phecode
340 Migraine Neurological 1.02 0.983 – 1.06 0.274 2860 28602 all phecode
340.1 Migrain with aura Neurological 1.1 0.955 – 1.28 0.181 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.998 0.877 – 1.14 0.973 252 2535 all phecode
342 Hemiplegia Neurological 0.989 0.938 – 1.04 0.693 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 1.24 1.03 – 1.48 0.0199 145 1450 all phecode
344 Other paralytic syndromes Neurological 0.961 0.889 – 1.04 0.327 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.989 0.961 – 1.02 0.466 5023 50270 all phecode
345.1 Epilepsy Neurological 0.957 0.893 – 1.03 0.212 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 0.873 0.795 – 0.959 0.00466 439 4385 all phecode
345.12 Partial epilepsy Neurological 0.968 0.859 – 1.09 0.592 277 2776 all phecode
345.3 Convulsions Neurological 1.02 0.979 – 1.07 0.323 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.919 0.78 – 1.08 0.309 144 1438 all phecode
348 Other conditions of brain Neurological 1.04 0.966 – 1.12 0.289 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 1.09 0.953 – 1.24 0.217 268 2678 all phecode
348.4 Cerebral cysts Neurological 0.981 0.823 – 1.17 0.829 133 1350 all phecode
348.7 Coma Neurological 1.02 0.917 – 1.14 0.675 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.02 0.895 – 1.16 0.765 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 0.984 0.888 – 1.09 0.758 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.929 0.834 – 1.04 0.188 342 3414 all phecode
350 Abnormal movement Neurological 0.971 0.933 – 1.01 0.14 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 0.973 0.908 – 1.04 0.441 887 8852 all phecode
350.2 Abnormality of gait Neurological 0.967 0.918 – 1.02 0.194 1596 15969 all phecode
350.3 Lack of coordination Neurological 0.96 0.864 – 1.07 0.452 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.1 0.841 – 1.44 0.483 54 540 all phecode
351 Other peripheral nerve disorders Neurological 1 0.984 – 1.02 0.768 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 0.973 0.921 – 1.03 0.322 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.05 0.957 – 1.16 0.292 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 0.962 0.897 – 1.03 0.268 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 1.02 0.957 – 1.08 0.572 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 1.14 0.934 – 1.39 0.198 114 1138 all phecode
353.2 Nerve root lesions Neurological 0.944 0.729 – 1.22 0.661 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.992 0.843 – 1.17 0.922 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 0.94 0.89 – 0.993 0.0266 1361 13648 all phecode
358 Myoneural disorders Neurological 0.987 0.86 – 1.13 0.849 211 2109 all phecode
358.1 Myasthenia gravis Neurological 0.948 0.823 – 1.09 0.462 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.975 0.887 – 1.07 0.598 465 4646 all phecode
359.1 Muscular dystrophies Neurological 1.13 0.936 – 1.36 0.204 122 1219 all phecode
359.2 Myopathy Neurological 0.927 0.833 – 1.03 0.165 360 3597 all phecode
360 Disorders of the globe Sense Organs 1.02 0.908 – 1.14 0.775 337 3367 all phecode
360.2 Progressive myopia Sense Organs 1.01 0.891 – 1.15 0.834 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 0.978 0.944 – 1.01 0.23 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.986 0.934 – 1.04 0.62 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 1.04 0.807 – 1.33 0.78 68 680 all phecode
362 Other retinal disorders Sense Organs 0.999 0.966 – 1.03 0.94 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.988 0.945 – 1.03 0.58 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.989 0.947 – 1.03 0.619 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.981 0.838 – 1.15 0.812 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 0.918 0.753 – 1.12 0.393 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.989 0.922 – 1.06 0.759 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 1 0.864 – 1.17 0.95 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.16 0.914 – 1.47 0.225 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.03 0.851 – 1.24 0.786 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.07 0.916 – 1.26 0.378 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 1 0.79 – 1.27 0.984 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.966 0.892 – 1.05 0.394 647 6485 all phecode
364.1 Corneal opacity Sense Organs 0.889 0.72 – 1.1 0.277 90 910 all phecode
364.2 Corneal edema Sense Organs 1.01 0.802 – 1.28 0.916 79 800 all phecode
364.4 Corneal degenerations Sense Organs 0.885 0.768 – 1.02 0.094 201 2017 all phecode
364.41 Keratoconus Sense Organs 0.951 0.769 – 1.17 0.639 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 1.01 0.882 – 1.17 0.837 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 1.09 0.883 – 1.33 0.434 100 1000 all phecode
365 Glaucoma Sense Organs 0.994 0.963 – 1.02 0.685 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 0.988 0.927 – 1.05 0.705 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 0.985 0.924 – 1.05 0.644 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.98 0.908 – 1.06 0.614 698 6996 all phecode
366 Cataract Sense Organs 1 0.986 – 1.02 0.896 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 0.993 0.78 – 1.26 0.951 69 700 all phecode
366.2 Senile cataract Sense Organs 1 0.977 – 1.02 0.987 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 0.911 0.751 – 1.1 0.34 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.997 0.956 – 1.04 0.873 2408 24092 all phecode
367.1 Myopia Sense Organs 0.969 0.914 – 1.03 0.28 1251 12519 all phecode
367.2 Astigmatism Sense Organs 1.03 0.882 – 1.19 0.737 190 1899 all phecode
367.8 Hypermetropia Sense Organs 1.02 0.891 – 1.16 0.809 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 1.03 0.957 – 1.12 0.404 719 7198 all phecode
368 Visual disturbances Sense Organs 0.969 0.933 – 1.01 0.0969 2962 29648 all phecode
368.1 Amblyopia Sense Organs 1.04 0.951 – 1.14 0.389 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.996 0.923 – 1.08 0.928 727 7288 all phecode
368.3 Anisometropia Sense Organs 0.906 0.774 – 1.06 0.22 154 1548 all phecode
368.4 Visual field defects Sense Organs 0.928 0.831 – 1.04 0.186 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 0.882 0.815 – 0.954 0.00182 612 6115 all phecode
369 Infection of the eye Sense Organs 0.95 0.87 – 1.04 0.25 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 0.994 0.828 – 1.19 0.949 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.998 0.865 – 1.15 0.98 213 2128 all phecode
370 Keratitis Sense Organs 0.967 0.856 – 1.09 0.584 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 0.985 0.831 – 1.17 0.863 141 1408 all phecode
371 Inflammation of the eye Sense Organs 0.98 0.944 – 1.02 0.276 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.973 0.887 – 1.07 0.554 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 0.986 0.945 – 1.03 0.516 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 1.01 0.936 – 1.09 0.817 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 1.01 0.983 – 1.04 0.454 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 1.05 0.986 – 1.12 0.127 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 1.01 0.966 – 1.06 0.582 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 1.02 0.98 – 1.07 0.28 2204 22031 all phecode
375.2 Epiphora Sense Organs 1.04 0.966 – 1.11 0.317 898 8969 all phecode
376 Disorders of the orbit Sense Organs 1.04 0.829 – 1.3 0.739 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.971 0.873 – 1.08 0.594 361 3618 all phecode
377.1 Optic atrophy Sense Organs 0.993 0.764 – 1.29 0.959 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.04 0.866 – 1.25 0.671 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.03 0.972 – 1.09 0.336 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.06 0.992 – 1.14 0.0836 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.09 0.947 – 1.26 0.222 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 0.881 0.78 – 0.995 0.0412 275 2755 all phecode
379 Other disorders of eye Sense Organs 1.01 0.975 – 1.04 0.628 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 0.995 0.941 – 1.05 0.866 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.01 0.96 – 1.06 0.75 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 0.917 0.723 – 1.16 0.475 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.978 0.885 – 1.08 0.671 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.971 0.833 – 1.13 0.707 169 1690 all phecode
380 Disorders of external ear Sense Organs 0.978 0.902 – 1.06 0.581 642 6413 all phecode
380.1 Otitis externa Sense Organs 0.988 0.901 – 1.08 0.793 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 1.05 0.941 – 1.16 0.398 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.04 0.99 – 1.08 0.129 2150 21493 all phecode
381.1 Otitis media Sense Organs 1.04 0.993 – 1.1 0.0919 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1 0.933 – 1.07 0.99 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 0.998 0.862 – 1.15 0.973 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 0.948 0.812 – 1.11 0.496 171 1709 all phecode
381.9 Otorrhea Sense Organs 1.04 0.916 – 1.18 0.561 281 2807 all phecode
382 Otalgia Sense Organs 0.897 0.8 – 1.01 0.0652 308 3084 all phecode
383 Otosclerosis Sense Organs 1 0.891 – 1.12 0.989 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.02 0.963 – 1.08 0.494 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.01 0.944 – 1.07 0.831 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.996 0.926 – 1.07 0.911 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 1.02 0.938 – 1.11 0.655 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.958 0.84 – 1.09 0.519 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.947 0.902 – 0.994 0.027 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 0.921 0.847 – 1 0.0536 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 0.975 0.877 – 1.08 0.634 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 0.992 0.922 – 1.07 0.83 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.991 0.961 – 1.02 0.56 4582 45806 all phecode
388 Other disorders of ear Sense Organs 0.864 0.752 – 0.993 0.0396 202 2017 all phecode
389 Hearing loss Sense Organs 1.01 0.977 – 1.04 0.59 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 1 0.911 – 1.11 0.94 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 1.07 0.968 – 1.18 0.19 450 4497 all phecode
389.4 Tinnitus Sense Organs 1.03 0.937 – 1.13 0.567 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 0.993 0.964 – 1.02 0.621 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 0.988 0.952 – 1.03 0.541 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 0.989 0.934 – 1.05 0.707 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 0.968 0.91 – 1.03 0.317 1058 10566 all phecode
395 Heart valve disorders Circulatory System 0.995 0.964 – 1.03 0.745 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.986 0.949 – 1.02 0.476 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.942 0.834 – 1.06 0.339 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 0.93 0.763 – 1.13 0.475 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.03 0.84 – 1.27 0.756 97 970 all phecode
395.6 Heart valve replaced Circulatory System 1.02 0.962 – 1.07 0.576 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 0.961 0.902 – 1.02 0.219 1048 10468 all phecode
401 Hypertension Circulatory System 1.01 0.997 – 1.01 0.184 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 1.01 0.997 – 1.01 0.172 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.01 0.963 – 1.06 0.699 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 1 0.903 – 1.12 0.933 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.01 0.96 – 1.07 0.682 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 1.02 0.853 – 1.22 0.834 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 0.967 0.917 – 1.02 0.221 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 1.01 1 – 1.03 0.0167 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.01 0.983 – 1.04 0.433 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 1.01 0.995 – 1.03 0.153 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 1.03 1.01 – 1.04 0.00198 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 1.01 0.998 – 1.03 0.0868 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.06 0.979 – 1.15 0.154 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.01 0.991 – 1.02 0.372 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.994 0.938 – 1.05 0.847 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 1.02 0.971 – 1.07 0.45 1823 18228 all phecode
414.2 ASCVD Circulatory System 0.864 0.683 – 1.09 0.226 72 719 all phecode
415 Pulmonary heart disease Circulatory System 0.992 0.962 – 1.02 0.593 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.956 0.759 – 1.2 0.701 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.946 0.87 – 1.03 0.199 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 0.95 0.862 – 1.05 0.3 448 4475 all phecode
416 Cardiomegaly Circulatory System 1 0.963 – 1.04 0.908 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 0.998 0.986 – 1.01 0.78 28599 270106 all phecode
418.1 Precordial pain Circulatory System 0.998 0.964 – 1.03 0.926 3551 35541 all phecode
420 Carditis Circulatory System 0.979 0.936 – 1.02 0.35 2106 21053 all phecode
420.1 Myocarditis Circulatory System 0.993 0.828 – 1.19 0.936 127 1267 all phecode
420.2 Pericarditis Circulatory System 0.959 0.907 – 1.01 0.136 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 0.948 0.831 – 1.08 0.429 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 0.967 0.802 – 1.17 0.722 113 1129 all phecode
420.3 Endocarditis Circulatory System 1 0.927 – 1.08 0.957 719 7194 all phecode
425 Cardiomyopathy Circulatory System 1.03 0.971 – 1.09 0.325 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.04 0.983 – 1.11 0.163 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.07 0.894 – 1.28 0.464 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.02 0.87 – 1.21 0.769 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 0.796 0.626 – 1.01 0.063 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 1.02 0.997 – 1.05 0.0897 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 1.04 0.996 – 1.09 0.0765 2114 21162 all phecode
426.21 First degree AV block Circulatory System 1.02 0.957 – 1.09 0.523 986 9867 all phecode
426.23 Second degree AV block Circulatory System 1.04 0.943 – 1.15 0.424 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 1.02 0.941 – 1.11 0.583 587 5868 all phecode
426.25 Other heart block Circulatory System 0.969 0.812 – 1.16 0.726 131 1318 all phecode
426.3 Bundle branch block Circulatory System 1.01 0.976 – 1.05 0.524 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 1.02 0.965 – 1.07 0.514 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 1.02 0.967 – 1.07 0.536 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.07 0.929 – 1.23 0.356 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 0.752 0.588 – 0.962 0.0231 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.02 0.981 – 1.07 0.299 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.02 0.979 – 1.07 0.32 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 1.01 1 – 1.03 0.0495 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.01 0.978 – 1.05 0.438 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.03 0.983 – 1.07 0.241 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1 0.94 – 1.07 0.888 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.01 0.991 – 1.03 0.335 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.03 0.989 – 1.06 0.173 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.02 0.961 – 1.08 0.51 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.04 0.934 – 1.17 0.449 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 1.01 0.95 – 1.08 0.675 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.02 0.955 – 1.09 0.55 952 9541 all phecode
427.6 Premature beats Circulatory System 0.956 0.875 – 1.04 0.31 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 1.06 0.876 – 1.28 0.553 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 1.02 0.979 – 1.07 0.307 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.96 0.869 – 1.06 0.428 402 4029 all phecode
427.9 Palpitations Circulatory System 1.01 0.974 – 1.04 0.675 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.982 0.955 – 1.01 0.183 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 0.993 0.95 – 1.04 0.761 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 0.982 0.952 – 1.01 0.244 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 0.998 0.924 – 1.08 0.957 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 1.33 1.01 – 1.75 0.044 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1.04 0.948 – 1.14 0.421 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 0.897 0.779 – 1.03 0.127 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 0.973 0.929 – 1.02 0.264 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.93 0.866 – 0.999 0.0474 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1.01 0.936 – 1.09 0.837 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 0.998 0.881 – 1.13 0.973 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 1.01 0.985 – 1.03 0.524 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.991 0.934 – 1.05 0.765 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 0.952 0.833 – 1.09 0.472 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 1.02 0.988 – 1.05 0.23 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.04 0.991 – 1.1 0.109 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 1.02 0.978 – 1.06 0.397 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.01 0.967 – 1.06 0.62 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 1.04 0.936 – 1.16 0.457 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.01 0.955 – 1.07 0.694 1279 12783 all phecode
440 Atherosclerosis Circulatory System 1.03 0.978 – 1.09 0.24 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.04 0.853 – 1.26 0.712 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.03 0.961 – 1.11 0.369 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 1.07 0.943 – 1.21 0.295 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.07 0.979 – 1.16 0.143 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.15 1.01 – 1.31 0.0312 283 2827 all phecode
442 Other aneurysm Circulatory System 0.974 0.93 – 1.02 0.269 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 0.984 0.933 – 1.04 0.545 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.976 0.913 – 1.04 0.476 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 0.844 0.699 – 1.02 0.0779 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.95 0.816 – 1.1 0.503 169 1696 all phecode
442.4 Arterial dissection Circulatory System 0.708 0.551 – 0.909 0.0069 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 0.989 0.861 – 1.14 0.875 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 0.996 0.964 – 1.03 0.826 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 0.974 0.917 – 1.03 0.394 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.995 0.896 – 1.1 0.928 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1 0.967 – 1.03 0.99 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.01 0.967 – 1.05 0.738 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 1 0.938 – 1.07 0.93 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.987 0.906 – 1.08 0.768 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.02 0.947 – 1.09 0.63 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 0.941 0.817 – 1.08 0.397 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 0.991 0.892 – 1.1 0.867 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 1.04 0.911 – 1.2 0.537 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 1.04 0.98 – 1.1 0.208 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 0.997 0.93 – 1.07 0.934 868 8712 all phecode
448 Disease of capillaries Circulatory System 1.11 0.934 – 1.33 0.231 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.974 0.902 – 1.05 0.503 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.989 0.957 – 1.02 0.497 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.979 0.947 – 1.01 0.223 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 1 0.921 – 1.09 0.932 564 5645 all phecode
454 Varicose veins Circulatory System 0.995 0.976 – 1.01 0.609 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 0.994 0.975 – 1.01 0.532 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.11 1.02 – 1.21 0.0172 624 6325 all phecode
455 Hemorrhoids Circulatory System 1 0.986 – 1.01 0.976 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.03 0.882 – 1.2 0.709 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.914 0.747 – 1.12 0.386 97 967 all phecode
458 Hypotension Circulatory System 0.992 0.966 – 1.02 0.569 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 1.03 0.973 – 1.09 0.311 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 0.995 0.869 – 1.14 0.937 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 0.991 0.957 – 1.03 0.595 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 1.01 0.99 – 1.02 0.443 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 0.953 0.806 – 1.13 0.57 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 1.01 0.99 – 1.02 0.457 16103 159422 all phecode
464 Acute sinusitis Respiratory 0.992 0.858 – 1.15 0.911 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.03 0.985 – 1.07 0.203 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 0.992 0.924 – 1.07 0.832 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.03 0.88 – 1.21 0.705 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.97 0.942 – 0.999 0.0424 4654 46553 all phecode
471 Nasal polyps Respiratory 0.979 0.945 – 1.01 0.229 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.973 0.912 – 1.04 0.419 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1 0.961 – 1.04 0.989 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 1.06 0.867 – 1.3 0.56 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.982 0.867 – 1.11 0.774 264 2647 all phecode
473.4 Voice disturbance Respiratory 1 0.939 – 1.06 0.993 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 0.974 0.928 – 1.02 0.279 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 0.933 0.857 – 1.02 0.115 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.995 0.935 – 1.06 0.861 1122 11199 all phecode
475 Chronic sinusitis Respiratory 0.996 0.956 – 1.04 0.841 2589 25882 all phecode
476 Allergic rhinitis Respiratory 1.02 0.953 – 1.08 0.612 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 1.03 0.986 – 1.07 0.193 2447 24452 all phecode
478 Throat pain Respiratory 0.93 0.837 – 1.03 0.17 377 3789 all phecode
479 Other upper respiratory disease Respiratory 0.983 0.952 – 1.02 0.301 4074 40737 all phecode
480 Pneumonia Respiratory 1 0.98 – 1.02 0.961 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 0.999 0.974 – 1.02 0.948 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 1 0.976 – 1.03 0.865 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 0.97 0.788 – 1.19 0.77 93 929 all phecode
480.2 Viral pneumonia Respiratory 1.17 0.9 – 1.52 0.241 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.941 0.771 – 1.15 0.547 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.99 0.921 – 1.06 0.785 794 7951 all phecode
481 Influenza Respiratory 1.01 0.9 – 1.13 0.892 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.943 0.814 – 1.09 0.438 193 1930 all phecode
495 Asthma Respiratory 1 0.991 – 1.02 0.565 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 1.14 0.991 – 1.3 0.0681 250 2510 all phecode
496 Chronic airway obstruction Respiratory 1.01 0.985 – 1.03 0.609 10424 101546 all phecode
496.1 Emphysema Respiratory 0.991 0.943 – 1.04 0.714 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 1 0.967 – 1.04 0.799 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.01 0.971 – 1.05 0.608 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 1.01 0.96 – 1.06 0.776 1885 18859 all phecode
497 Bronchitis Respiratory 1.09 1 – 1.19 0.0417 626 6267 all phecode
500 Lung disease due to external agents Respiratory 1 0.905 – 1.11 0.99 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.18 0.928 – 1.51 0.175 79 784 all phecode
500.2 Pneumoconiosis Respiratory 0.995 0.874 – 1.13 0.934 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 0.995 0.919 – 1.08 0.911 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.982 0.918 – 1.05 0.599 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 1.23 1.11 – 1.35 4.73e-05 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.926 0.827 – 1.04 0.177 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 0.979 0.757 – 1.27 0.873 61 610 all phecode
506 Empyema and pneumothorax Respiratory 0.989 0.931 – 1.05 0.718 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 1 0.979 – 1.03 0.752 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.02 0.978 – 1.07 0.315 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.01 0.967 – 1.05 0.764 2599 26031 all phecode
509.1 Respiratory failure Respiratory 0.993 0.949 – 1.04 0.758 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 0.987 0.941 – 1.04 0.606 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 0.893 0.759 – 1.05 0.171 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.09 0.981 – 1.22 0.108 386 3863 all phecode
510 Other diseases of lung Respiratory 0.918 0.853 – 0.988 0.0222 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 0.98 0.959 – 1 0.0626 9031 90349 all phecode
512.1 Wheezing Respiratory 1.01 0.876 – 1.16 0.904 220 2196 all phecode
512.2 Painful respiration Respiratory 0.922 0.8 – 1.06 0.26 207 2075 all phecode
512.7 Shortness of breath Respiratory 0.982 0.956 – 1.01 0.188 5842 58498 all phecode
512.8 Cough Respiratory 0.963 0.927 – 1 0.0516 2866 28642 all phecode
512.9 Other dyspnea Respiratory 1.01 0.944 – 1.08 0.75 914 9124 all phecode
513 Respiratory abnormalities Respiratory 1.04 0.955 – 1.13 0.373 611 6112 all phecode
513.3 Hypoventilation Respiratory 0.997 0.794 – 1.25 0.979 83 830 all phecode
513.4 Hyperventilation Respiratory 1.09 0.961 – 1.24 0.177 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 0.996 0.845 – 1.18 0.965 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 0.988 0.948 – 1.03 0.575 2465 24673 all phecode
516 Abnormal sputum Respiratory 0.994 0.95 – 1.04 0.781 2132 21335 all phecode
516.1 Hemoptysis Respiratory 0.991 0.947 – 1.04 0.696 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.02 0.995 – 1.04 0.135 9366 93681 all phecode
519.2 Respiratory complications Respiratory 0.983 0.878 – 1.1 0.766 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.02 0.998 – 1.04 0.071 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.01 0.9 – 1.14 0.848 303 3049 all phecode
520 Disorders of tooth development Digestive 0.989 0.946 – 1.03 0.635 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.988 0.749 – 1.3 0.931 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 1.02 0.976 – 1.06 0.409 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 0.994 0.957 – 1.03 0.744 3016 30245 all phecode
521.1 Dental caries Digestive 0.994 0.957 – 1.03 0.741 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 0.976 0.93 – 1.02 0.334 1774 17750 all phecode
522.5 Periapical abscess Digestive 0.98 0.924 – 1.04 0.509 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 0.99 0.941 – 1.04 0.685 1681 16812 all phecode
523.1 Gingivitis Digestive 1.03 0.853 – 1.24 0.772 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 0.98 0.923 – 1.04 0.503 1165 11650 all phecode
523.31 Acute periodontitis Digestive 1.02 0.938 – 1.1 0.695 666 6667 all phecode
523.32 Chronic periodontitis Digestive 0.969 0.889 – 1.06 0.473 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.925 0.829 – 1.03 0.16 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.972 0.866 – 1.09 0.628 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.05 1.01 – 1.1 0.0144 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.867 0.693 – 1.09 0.215 72 720 all phecode
526 Diseases of the jaws Digestive 0.981 0.917 – 1.05 0.575 928 9279 all phecode
526.1 Cysts of the jaws Digestive 1.05 0.934 – 1.17 0.426 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.866 0.679 – 1.1 0.248 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 0.932 0.819 – 1.06 0.281 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.921 0.809 – 1.05 0.212 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 1.05 0.86 – 1.29 0.624 110 1098 all phecode
526.9 Jaw disease NOS Digestive 0.986 0.858 – 1.13 0.841 233 2329 all phecode
527 Diseases of the salivary glands Digestive 1.01 0.934 – 1.09 0.786 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 0.911 0.736 – 1.13 0.393 84 838 all phecode
527.2 Sialoadenitis Digestive 1.04 0.933 – 1.16 0.481 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 1.12 0.85 – 1.48 0.415 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.01 0.838 – 1.21 0.936 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.999 0.967 – 1.03 0.972 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 0.951 0.866 – 1.04 0.286 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.958 0.865 – 1.06 0.411 389 3884 all phecode
528.12 Oral aphthae Digestive 0.871 0.705 – 1.08 0.202 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.934 0.804 – 1.08 0.367 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 1.03 0.851 – 1.26 0.735 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 1.1 0.874 – 1.37 0.429 94 940 all phecode
528.5 Diseases of lips Digestive 0.966 0.894 – 1.04 0.385 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 1.14 1.01 – 1.29 0.03 308 3079 all phecode
528.7 Sialolithiasis Digestive 1.06 0.94 – 1.19 0.359 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 1.01 0.952 – 1.07 0.763 1232 12312 all phecode
529.1 Glossitis Digestive 0.917 0.816 – 1.03 0.144 299 2986 all phecode
530 Diseases of esophagus Digestive 1 0.993 – 1.02 0.446 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1 0.989 – 1.01 0.885 31253 272429 all phecode
530.11 GERD Digestive 0.999 0.985 – 1.01 0.832 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 0.98 0.953 – 1.01 0.166 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 0.987 0.967 – 1.01 0.185 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.07 1.02 – 1.13 0.00799 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 0.991 0.945 – 1.04 0.695 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 1.01 0.93 – 1.09 0.837 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.02 0.868 – 1.21 0.787 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.08 0.963 – 1.21 0.192 341 3416 all phecode
530.9 Heartburn Digestive 1 0.96 – 1.05 0.835 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.01 0.988 – 1.04 0.318 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.966 0.892 – 1.05 0.397 637 6374 all phecode
531.2 Gastric ulcer Digestive 1.03 0.996 – 1.06 0.0866 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 1 0.965 – 1.04 0.944 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 1.06 0.959 – 1.17 0.249 427 4268 all phecode
532 Dysphagia Digestive 1.01 0.983 – 1.03 0.51 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 1.01 0.999 – 1.02 0.064 28078 261548 all phecode
535.1 Acute gastritis Digestive 1.01 0.956 – 1.08 0.631 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 1.03 0.922 – 1.14 0.645 370 3687 all phecode
535.6 Duodenitis Digestive 1.02 0.994 – 1.04 0.149 7592 75928 all phecode
535.8 Other specified gastritis Digestive 1.01 0.984 – 1.03 0.564 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.964 0.802 – 1.16 0.7 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.01 0.889 – 1.14 0.919 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 1 0.969 – 1.04 0.819 3391 33907 all phecode
540 Appendiceal conditions Digestive 1.03 0.997 – 1.07 0.069 3088 30890 all phecode
540.1 Appendicitis Digestive 1.04 1 – 1.08 0.039 2895 28963 all phecode
540.11 Acute appendicitis Digestive 1.04 0.998 – 1.08 0.0618 2601 26019 all phecode
550 Abdominal hernia Digestive 1.01 0.996 – 1.02 0.275 45429 282640 all phecode
550.1 Inguinal hernia Digestive 1.01 0.99 – 1.02 0.442 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 1.01 0.993 – 1.02 0.413 26494 238953 all phecode
550.3 Femoral hernia Digestive 1.02 0.943 – 1.11 0.592 651 6504 all phecode
550.4 Umbilical hernia Digestive 0.995 0.962 – 1.03 0.757 3705 37072 all phecode
550.5 Ventral hernia Digestive 1.01 0.975 – 1.05 0.564 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.01 0.978 – 1.04 0.596 4444 44442 all phecode
555.1 Regional enteritis Digestive 1 0.956 – 1.06 0.847 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 1.02 0.98 – 1.05 0.391 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.03 0.943 – 1.13 0.492 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 0.936 0.88 – 0.996 0.0373 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 0.975 0.902 – 1.05 0.534 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.987 0.876 – 1.11 0.836 299 2987 all phecode
557.1 Celiac disease Digestive 1.08 1.03 – 1.13 0.00294 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 0.99 0.974 – 1.01 0.234 15492 155105 all phecode
559 Ileostomy status Digestive 1.03 0.981 – 1.09 0.225 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 0.992 0.96 – 1.02 0.622 3936 39337 all phecode
560.1 Paralytic ileus Digestive 0.977 0.894 – 1.07 0.61 523 5231 all phecode
560.2 Impaction of intestine Digestive 0.976 0.864 – 1.1 0.699 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.03 0.955 – 1.1 0.477 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 1 0.966 – 1.04 0.972 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 1 0.984 – 1.02 0.958 15772 157686 all phecode
561.1 Diarrhea Digestive 0.968 0.88 – 1.06 0.497 466 4653 all phecode
561.2 Flatulence Digestive 0.987 0.939 – 1.04 0.611 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 1.01 0.996 – 1.02 0.158 26714 211692 all phecode
562.1 Diverticulosis Digestive 1.01 0.997 – 1.02 0.151 26672 211642 all phecode
563 Constipation Digestive 1.01 0.989 – 1.03 0.393 10314 103140 all phecode
564 Functional digestive disorders Digestive 1.01 0.996 – 1.02 0.182 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 1 0.975 – 1.03 0.867 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.01 0.959 – 1.06 0.707 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 1.01 0.995 – 1.03 0.18 15186 151648 all phecode
565 Anal and rectal conditions Digestive 1 0.985 – 1.02 0.856 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 1 0.976 – 1.02 0.976 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 0.995 0.93 – 1.06 0.883 929 9293 all phecode
568 Other disorders of peritoneum Digestive 0.991 0.956 – 1.03 0.627 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.995 0.959 – 1.03 0.781 3101 30987 all phecode
569 Other disorders of intestine Digestive 0.993 0.962 – 1.03 0.677 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 1.08 0.906 – 1.28 0.398 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 0.929 0.849 – 1.02 0.11 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 1 0.966 – 1.04 0.859 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 0.976 0.929 – 1.03 0.346 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.09 0.894 – 1.32 0.401 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 0.945 0.831 – 1.07 0.384 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.07 0.999 – 1.14 0.055 976 9804 all phecode
571.81 Portal hypertension Digestive 1.08 0.99 – 1.19 0.0802 528 5285 all phecode
572 Ascites (non malignant) Digestive 0.99 0.94 – 1.04 0.709 1544 15454 all phecode
573 Other disorders of liver Digestive 0.997 0.945 – 1.05 0.901 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 1.17 0.933 – 1.47 0.171 96 960 all phecode
573.3 Hepatomegaly Digestive 1.09 0.963 – 1.23 0.174 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 1.04 0.975 – 1.12 0.218 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 0.997 0.963 – 1.03 0.873 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.01 0.878 – 1.16 0.914 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 1.01 0.997 – 1.03 0.0974 15607 156123 all phecode
574.1 Cholelithiasis Digestive 1.02 0.999 – 1.04 0.0635 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.05 0.995 – 1.11 0.0742 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.993 0.966 – 1.02 0.64 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 1 0.965 – 1.05 0.832 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.03 0.993 – 1.08 0.105 2748 27523 all phecode
575 Other biliary tract disease Digestive 1.01 0.973 – 1.04 0.724 3867 38724 all phecode
575.1 Cholangitis Digestive 1.05 0.954 – 1.15 0.337 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 1.04 0.966 – 1.12 0.29 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 1.04 0.944 – 1.15 0.43 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 0.99 0.937 – 1.05 0.714 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 1.01 0.945 – 1.07 0.814 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.958 0.86 – 1.07 0.436 348 3488 all phecode
577 Diseases of pancreas Digestive 0.989 0.95 – 1.03 0.569 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 0.994 0.949 – 1.04 0.799 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 1.06 0.97 – 1.17 0.191 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.996 0.895 – 1.11 0.942 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 0.995 0.981 – 1.01 0.53 20626 206278 all phecode
578.1 Hematemesis Digestive 1.04 0.997 – 1.09 0.0676 1958 19564 all phecode
578.2 Blood in stool Digestive 1.02 0.981 – 1.06 0.316 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 0.99 0.972 – 1.01 0.252 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1 0.976 – 1.03 0.79 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.01 0.961 – 1.07 0.643 1548 15498 all phecode
579.2 Splenomegaly Digestive 1.02 0.923 – 1.13 0.701 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.984 0.935 – 1.04 0.535 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.967 0.918 – 1.02 0.205 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 0.972 0.913 – 1.04 0.381 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.99 0.792 – 1.24 0.929 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.24 1.03 – 1.5 0.021 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.95 0.887 – 1.02 0.138 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.925 0.844 – 1.01 0.0929 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1 0.881 – 1.14 0.953 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.986 0.868 – 1.12 0.825 253 2529 all phecode
585 Renal failure Genitourinary 0.996 0.972 – 1.02 0.764 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 0.995 0.965 – 1.03 0.768 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 1 0.951 – 1.06 0.905 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.996 0.957 – 1.04 0.853 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 0.956 0.874 – 1.05 0.325 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.01 0.974 – 1.05 0.6 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.09 0.939 – 1.26 0.261 208 2089 all phecode
586.11 Small kidney Genitourinary 1.06 0.904 – 1.24 0.486 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1 0.945 – 1.06 0.97 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.969 0.774 – 1.21 0.781 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.977 0.912 – 1.05 0.508 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 0.969 0.871 – 1.08 0.556 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 0.904 0.736 – 1.11 0.334 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 0.988 0.821 – 1.19 0.899 116 1158 all phecode
590 Pyelonephritis Genitourinary 0.981 0.927 – 1.04 0.501 1328 13285 all phecode
591 Urinary tract infection Genitourinary 1.01 0.995 – 1.03 0.139 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 1 0.964 – 1.04 0.961 2966 29661 all phecode
592.1 Cystitis Genitourinary 1.01 0.968 – 1.05 0.755 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 1.02 0.862 – 1.22 0.787 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 1 0.937 – 1.08 0.908 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 1.06 0.924 – 1.21 0.429 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.933 0.801 – 1.09 0.369 165 1662 all phecode
593 Hematuria Genitourinary 1.02 1.01 – 1.04 0.00634 16068 160204 all phecode
594 Urinary calculus Genitourinary 1.03 1 – 1.06 0.0298 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 1.02 0.983 – 1.06 0.298 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.12 1.04 – 1.21 0.00345 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 1.02 0.982 – 1.07 0.272 2401 24024 all phecode
594.8 Renal colic Genitourinary 1.02 0.973 – 1.07 0.446 2050 20500 all phecode
595 Hydronephrosis Genitourinary 1.03 0.983 – 1.08 0.219 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 1 0.98 – 1.02 0.97 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 1.05 1 – 1.1 0.0432 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 0.988 0.94 – 1.04 0.629 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.985 0.954 – 1.02 0.376 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.988 0.953 – 1.02 0.5 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 0.94 0.752 – 1.17 0.585 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 0.998 0.964 – 1.03 0.893 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.987 0.878 – 1.11 0.823 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.994 – 1.03 0.221 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 1.09 0.929 – 1.28 0.283 166 1670 all phecode
599.2 Retention of urine Genitourinary 0.984 0.96 – 1.01 0.202 6718 67168 all phecode
599.3 Dysuria Genitourinary 1.01 0.95 – 1.07 0.778 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 1.01 0.991 – 1.04 0.241 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 0.994 0.962 – 1.03 0.699 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 1.14 0.925 – 1.4 0.223 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.09 0.831 – 1.42 0.549 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 0.972 0.928 – 1.02 0.242 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 0.995 0.975 – 1.01 0.59 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 1.01 0.965 – 1.06 0.688 2081 20818 all phecode
601.1 Prostatitis Genitourinary 0.99 0.94 – 1.04 0.703 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 0.997 0.876 – 1.14 0.965 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 0.992 0.927 – 1.06 0.814 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 0.863 0.667 – 1.12 0.26 59 588 all phecode
601.4 Balanoposthitis Genitourinary 1.04 0.919 – 1.17 0.566 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.03 0.916 – 1.16 0.608 303 3019 all phecode
602 Other disorders of prostate Genitourinary 0.968 0.916 – 1.02 0.246 1341 13408 all phecode
603 Other disorders of testis Genitourinary 1.03 0.982 – 1.07 0.251 2150 21512 all phecode
603.1 Hydrocele Genitourinary 1.05 0.995 – 1.11 0.0754 1339 13402 all phecode
604 Disorders of penis Genitourinary 1.01 0.971 – 1.04 0.715 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.03 0.992 – 1.07 0.119 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 0.921 0.818 – 1.04 0.172 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 0.987 0.95 – 1.03 0.509 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.04 0.907 – 1.2 0.558 214 2138 all phecode
609.1 Infertility, male Genitourinary 0.952 0.741 – 1.22 0.704 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 1.03 0.878 – 1.2 0.741 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 0.996 0.956 – 1.04 0.844 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 0.994 0.93 – 1.06 0.866 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 0.891 0.794 – 1 0.0491 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 1.03 0.916 – 1.16 0.609 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 1.01 0.959 – 1.07 0.625 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.03 0.954 – 1.12 0.426 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.964 0.916 – 1.02 0.165 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 0.874 0.673 – 1.14 0.313 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 0.964 0.915 – 1.02 0.173 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1 0.935 – 1.07 0.963 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1 0.936 – 1.08 0.903 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 0.867 0.689 – 1.09 0.225 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 1.07 1.02 – 1.13 0.00952 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 1.12 1.03 – 1.21 0.00743 720 7210 all phecode
613.5 Mastodynia Genitourinary 1.35 1.04 – 1.74 0.022 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 0.992 0.917 – 1.07 0.84 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 0.999 0.892 – 1.12 0.989 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 1.05 0.91 – 1.21 0.502 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.02 0.996 – 1.05 0.1 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.02 0.983 – 1.07 0.245 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1.02 0.947 – 1.09 0.638 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.888 0.68 – 1.16 0.381 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 1.03 0.936 – 1.14 0.51 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.979 0.877 – 1.09 0.699 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.01 0.891 – 1.14 0.908 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.03 0.989 – 1.07 0.149 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.03 0.971 – 1.09 0.353 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.974 0.883 – 1.07 0.601 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.09 1.01 – 1.18 0.0279 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.97 0.861 – 1.09 0.623 274 2737 all phecode
615 Endometriosis Genitourinary 1.02 0.984 – 1.05 0.328 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 0.893 0.797 – 1 0.0502 304 3037 all phecode
618 Genital prolapse Genitourinary 0.986 0.967 – 1 0.141 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 0.991 0.968 – 1.02 0.483 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.982 0.955 – 1.01 0.211 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.984 0.899 – 1.08 0.736 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.01 0.936 – 1.1 0.747 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.998 0.976 – 1.02 0.869 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.961 0.892 – 1.04 0.303 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 1.02 0.983 – 1.06 0.305 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.976 0.94 – 1.01 0.216 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.994 0.946 – 1.04 0.802 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.04 0.984 – 1.1 0.156 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 0.893 0.71 – 1.12 0.333 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 1.02 0.959 – 1.08 0.528 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 1 0.983 – 1.02 0.791 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 1.01 0.988 – 1.03 0.365 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.999 0.964 – 1.03 0.953 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 0.997 0.941 – 1.06 0.904 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 1.06 0.983 – 1.14 0.134 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 1.09 0.953 – 1.25 0.207 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 1.03 0.932 – 1.14 0.56 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 1.02 0.989 – 1.04 0.236 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1 0.965 – 1.04 0.884 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 1.01 0.955 – 1.08 0.631 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1 0.985 – 1.02 0.878 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.999 0.981 – 1.02 0.891 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 1.07 0.871 – 1.31 0.526 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 0.997 0.976 – 1.02 0.764 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 1.03 0.987 – 1.08 0.158 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.993 0.96 – 1.03 0.675 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 1.05 1 – 1.11 0.0392 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 0.94 0.803 – 1.1 0.445 159 1587 all phecode
626.8 Infertility, female Genitourinary 1.02 0.965 – 1.08 0.484 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.989 0.97 – 1.01 0.302 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 0.994 0.972 – 1.02 0.559 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 0.883 0.765 – 1.02 0.0875 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.02 0.959 – 1.09 0.524 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 0.909 0.81 – 1.02 0.104 310 3097 all phecode
628 Ovarian cyst Genitourinary 1.02 0.989 – 1.05 0.211 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.01 0.98 – 1.04 0.523 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.962 0.906 – 1.02 0.209 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.02 0.911 – 1.14 0.748 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.988 0.943 – 1.04 0.612 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.984 0.917 – 1.06 0.655 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.984 0.929 – 1.04 0.586 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.979 0.938 – 1.02 0.327 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.985 0.907 – 1.07 0.714 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.985 0.926 – 1.05 0.638 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 1.13 0.876 – 1.46 0.347 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.01 0.95 – 1.08 0.728 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.938 0.836 – 1.05 0.273 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.18 1.02 – 1.37 0.0243 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.11 0.942 – 1.32 0.206 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.992 0.936 – 1.05 0.797 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1 0.961 – 1.05 0.857 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.963 0.765 – 1.21 0.749 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.908 0.806 – 1.02 0.111 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.02 0.843 – 1.23 0.844 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1 0.859 – 1.17 0.995 193 1922 all phecode
650 Normal delivery Pregnancy Complications 0.996 0.95 – 1.04 0.862 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 1.01 0.907 – 1.13 0.799 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1.02 0.974 – 1.08 0.345 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.998 0.944 – 1.05 0.934 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 0.765 0.61 – 0.961 0.0212 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.02 0.988 – 1.05 0.212 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.954 0.787 – 1.16 0.631 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 1.04 0.991 – 1.08 0.12 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 1.02 0.936 – 1.12 0.592 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 1.02 0.986 – 1.05 0.296 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.01 0.964 – 1.05 0.807 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.16 0.975 – 1.38 0.0941 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.01 0.892 – 1.15 0.848 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.01 0.779 – 1.32 0.926 63 624 all phecode
679 Complications of in utero procedures Dermatologic 0.85 0.642 – 1.13 0.258 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 1 0.979 – 1.03 0.79 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.09 0.996 – 1.19 0.0626 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.968 0.886 – 1.06 0.473 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.999 0.972 – 1.03 0.953 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.997 0.97 – 1.03 0.856 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.998 0.971 – 1.03 0.903 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 0.935 0.862 – 1.01 0.108 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 0.897 0.849 – 0.947 8.92e-05 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 0.999 0.956 – 1.04 0.949 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 1.01 0.927 – 1.1 0.832 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 1.1 0.983 – 1.23 0.0969 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 0.927 0.851 – 1.01 0.0858 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.02 0.978 – 1.07 0.327 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 0.904 0.802 – 1.02 0.0967 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 0.941 0.773 – 1.15 0.545 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 0.987 0.95 – 1.03 0.519 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.02 0.995 – 1.05 0.11 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 1.19 0.927 – 1.53 0.171 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 1.23 0.907 – 1.66 0.184 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 1.28 1.04 – 1.57 0.0191 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 1.07 1 – 1.15 0.0438 986 9854 all phecode
694.1 Vitiligo Dermatologic 1.05 0.796 – 1.38 0.74 60 599 all phecode
694.2 Other dyschromia Dermatologic 1.08 1.01 – 1.17 0.0354 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 1.03 0.851 – 1.26 0.734 117 1170 all phecode
695 Erythematous conditions Dermatologic 1.01 0.97 – 1.06 0.562 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 0.915 0.757 – 1.11 0.359 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 0.994 0.834 – 1.19 0.95 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 0.935 0.716 – 1.22 0.624 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.978 0.768 – 1.24 0.855 73 727 all phecode
695.3 Rosacea Dermatologic 0.94 0.837 – 1.06 0.292 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.03 0.927 – 1.14 0.588 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.13 0.933 – 1.36 0.214 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.04 0.929 – 1.17 0.491 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 1.01 0.935 – 1.08 0.848 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 1.12 0.976 – 1.28 0.108 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 1.34 1.03 – 1.73 0.028 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 0.998 0.907 – 1.1 0.972 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 1.02 0.98 – 1.07 0.293 2252 22509 all phecode
696.4 Psoriasis Dermatologic 1.02 0.977 – 1.07 0.36 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 1.01 0.957 – 1.06 0.787 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.01 0.934 – 1.09 0.792 706 7052 all phecode
697 Sarcoidosis Dermatologic 0.964 0.883 – 1.05 0.408 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 0.985 0.916 – 1.06 0.688 782 7814 all phecode
700 Corns and callosities Dermatologic 1.06 0.933 – 1.2 0.383 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.988 0.959 – 1.02 0.431 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 0.919 0.74 – 1.14 0.443 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.969 0.929 – 1.01 0.143 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 0.86 0.666 – 1.11 0.249 61 610 all phecode
701.4 Keloid scar Dermatologic 1.03 0.89 – 1.18 0.73 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 0.948 0.862 – 1.04 0.278 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.1 0.898 – 1.35 0.352 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.999 0.971 – 1.03 0.929 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 1.01 0.965 – 1.05 0.79 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 0.994 0.958 – 1.03 0.758 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 0.946 0.849 – 1.05 0.315 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 0.942 0.884 – 1.01 0.0719 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 0.966 0.939 – 0.993 0.0148 5267 52727 all phecode
704.1 Alopecia Dermatologic 1.06 0.881 – 1.28 0.521 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.9 0.725 – 1.12 0.337 76 759 all phecode
705 Disorders of sweat glands Dermatologic 1.01 0.885 – 1.16 0.849 228 2287 all phecode
705.3 Hidradenitis Dermatologic 1.05 0.901 – 1.21 0.558 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 0.882 0.813 – 0.957 0.00242 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 0.963 0.941 – 0.984 0.000838 8317 83195 all phecode
706.1 Acne Dermatologic 0.754 0.604 – 0.942 0.013 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 0.971 0.95 – 0.992 0.00771 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 0.968 0.924 – 1.01 0.16 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 0.96 0.897 – 1.03 0.228 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.993 0.959 – 1.03 0.709 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 1.01 0.922 – 1.11 0.834 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 1.05 0.897 – 1.23 0.553 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.02 0.794 – 1.31 0.876 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.998 0.959 – 1.04 0.918 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.97 0.893 – 1.05 0.468 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 0.984 0.902 – 1.07 0.708 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.936 0.811 – 1.08 0.372 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.988 0.893 – 1.09 0.817 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 0.942 0.855 – 1.04 0.23 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 0.937 0.841 – 1.05 0.244 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 0.806 0.651 – 0.999 0.0493 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.863 0.737 – 1.01 0.0663 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 0.905 0.712 – 1.15 0.416 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1 0.971 – 1.03 0.974 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.01 0.977 – 1.04 0.607 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.02 0.972 – 1.08 0.396 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.06 0.876 – 1.29 0.532 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.97 0.894 – 1.05 0.468 618 6177 all phecode
716 Other arthropathies Musculoskeletal 0.992 0.981 – 1 0.152 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.99 0.956 – 1.02 0.561 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.994 0.978 – 1.01 0.491 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 0.993 0.982 – 1 0.213 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.998 0.939 – 1.06 0.939 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 0.979 0.947 – 1.01 0.22 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 0.995 0.972 – 1.02 0.686 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.986 0.958 – 1.02 0.352 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.951 0.823 – 1.1 0.497 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 0.991 0.889 – 1.1 0.872 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 0.977 0.956 – 0.998 0.0317 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.998 0.911 – 1.09 0.972 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.959 0.923 – 0.997 0.0324 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.07 0.828 – 1.38 0.611 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.967 0.938 – 0.997 0.034 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 0.945 0.864 – 1.03 0.212 517 5173 all phecode
723.1 Torticollis Musculoskeletal 0.911 0.755 – 1.1 0.333 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 0.974 0.931 – 1.02 0.251 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 1.04 0.939 – 1.15 0.445 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 1.05 0.945 – 1.16 0.373 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 0.874 0.687 – 1.11 0.272 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 0.963 0.915 – 1.01 0.143 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1 0.987 – 1.02 0.669 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 1 0.981 – 1.02 0.852 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 1.03 0.922 – 1.16 0.583 334 3336 all phecode
726.3 Bursitis Musculoskeletal 0.991 0.924 – 1.06 0.788 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.99 0.967 – 1.01 0.414 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.02 0.98 – 1.06 0.345 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 0.949 0.783 – 1.15 0.596 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.994 0.958 – 1.03 0.736 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 0.95 0.875 – 1.03 0.22 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1 0.898 – 1.12 0.969 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.943 0.795 – 1.12 0.503 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.992 0.959 – 1.03 0.631 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.927 0.841 – 1.02 0.128 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 0.994 0.961 – 1.03 0.712 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.996 0.962 – 1.03 0.825 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 0.988 0.962 – 1.01 0.367 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.999 0.935 – 1.07 0.969 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 1.03 0.84 – 1.26 0.787 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.974 0.86 – 1.1 0.671 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.965 0.851 – 1.1 0.582 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 1.03 0.939 – 1.14 0.492 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.08 0.936 – 1.25 0.286 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.915 0.702 – 1.19 0.509 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.991 0.944 – 1.04 0.721 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 0.994 0.883 – 1.12 0.926 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1 0.917 – 1.1 0.957 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 0.946 0.794 – 1.13 0.532 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.01 0.956 – 1.08 0.625 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 1.13 0.936 – 1.37 0.199 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 0.994 0.973 – 1.01 0.564 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 0.961 0.833 – 1.11 0.587 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 0.988 0.96 – 1.02 0.395 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.975 0.931 – 1.02 0.289 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 1 0.952 – 1.06 0.888 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.996 0.971 – 1.02 0.754 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.984 0.936 – 1.04 0.547 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 0.988 0.866 – 1.13 0.856 248 2476 all phecode
737 Curvature of spine Musculoskeletal 1.01 0.946 – 1.07 0.84 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.01 0.945 – 1.07 0.84 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.02 0.974 – 1.07 0.391 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.04 0.988 – 1.1 0.131 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 1.06 0.961 – 1.16 0.259 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 0.991 0.978 – 1 0.137 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.99 0.975 – 1.01 0.214 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.998 0.976 – 1.02 0.832 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.983 0.882 – 1.1 0.76 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.05 0.961 – 1.14 0.295 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.994 0.976 – 1.01 0.524 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.991 0.958 – 1.03 0.615 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 0.969 0.79 – 1.19 0.766 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 0.974 0.897 – 1.06 0.538 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 0.982 0.837 – 1.15 0.821 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 0.971 0.92 – 1.03 0.291 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 0.914 0.754 – 1.11 0.355 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 1.33 0.986 – 1.81 0.0619 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.968 0.931 – 1.01 0.0924 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 0.923 0.827 – 1.03 0.153 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.17 0.942 – 1.46 0.153 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 0.916 0.836 – 1 0.0616 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 0.975 0.931 – 1.02 0.273 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.985 0.962 – 1.01 0.221 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 0.991 0.966 – 1.02 0.499 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 0.994 0.967 – 1.02 0.653 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 0.996 0.911 – 1.09 0.927 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 0.972 0.887 – 1.06 0.534 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.956 0.891 – 1.03 0.216 815 8144 all phecode
745 Pain in joint Musculoskeletal 0.997 0.974 – 1.02 0.774 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.03 0.992 – 1.07 0.119 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.03 0.99 – 1.07 0.145 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1.06 0.971 – 1.16 0.192 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.04 0.905 – 1.19 0.589 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.01 0.963 – 1.06 0.664 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.05 0.901 – 1.24 0.506 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.862 0.656 – 1.13 0.284 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.947 0.841 – 1.07 0.369 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 1.01 0.934 – 1.09 0.822 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.993 0.888 – 1.11 0.897 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.11 0.953 – 1.28 0.185 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.01 0.907 – 1.13 0.842 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.01 0.884 – 1.16 0.872 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.08 0.887 – 1.3 0.456 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.06 1.01 – 1.12 0.03 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.1 1.01 – 1.19 0.0217 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.08 0.974 – 1.19 0.152 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.11 0.965 – 1.28 0.14 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.02 0.945 – 1.09 0.681 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.99 0.896 – 1.09 0.84 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.986 0.884 – 1.1 0.807 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.12 0.995 – 1.26 0.0609 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 1.04 0.909 – 1.18 0.589 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 1.08 0.933 – 1.25 0.303 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.29 1 – 1.67 0.0498 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.889 0.742 – 1.06 0.2 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.923 0.731 – 1.16 0.499 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.03 0.845 – 1.25 0.796 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.992 0.898 – 1.1 0.882 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.965 0.837 – 1.11 0.623 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.11 0.941 – 1.31 0.214 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.16 0.94 – 1.43 0.167 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.999 0.919 – 1.09 0.988 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.04 0.83 – 1.31 0.718 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.989 0.897 – 1.09 0.825 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.867 0.736 – 1.02 0.0884 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.856 0.668 – 1.1 0.222 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.04 0.904 – 1.2 0.586 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.04 0.85 – 1.28 0.684 96 959 all phecode
760 Back pain Symptoms 0.986 0.967 – 1.01 0.161 11126 111353 all phecode
761 Cervicalgia Symptoms 0.99 0.943 – 1.04 0.681 1791 17901 all phecode
764 Sciatica Symptoms 1.03 0.984 – 1.07 0.234 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.947 0.893 – 1 0.0722 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 0.893 0.826 – 0.966 0.00494 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.04 0.97 – 1.12 0.269 870 8687 all phecode
771.1 Swelling of limb Symptoms 0.989 0.96 – 1.02 0.49 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 0.942 0.87 – 1.02 0.136 659 6581 all phecode
773 Pain in limb Symptoms 1 0.976 – 1.03 0.898 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 1.04 0.89 – 1.22 0.608 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.956 0.912 – 1 0.0586 1870 18715 all phecode
782.3 Edema Symptoms 0.98 0.932 – 1.03 0.435 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 1.04 0.889 – 1.22 0.621 175 1748 all phecode
783 Fever of unknown origin Symptoms 0.992 0.96 – 1.03 0.644 3911 39105 all phecode
785 Abdominal pain Symptoms 0.999 0.989 – 1.01 0.844 40080 301686 all phecode
788 Syncope and collapse Symptoms 1.01 0.987 – 1.03 0.446 9069 90813 all phecode
789 Nausea and vomiting Symptoms 1.01 0.989 – 1.03 0.404 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 0.947 0.806 – 1.11 0.513 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 1.19 0.934 – 1.51 0.16 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 0.981 0.957 – 1.01 0.151 6357 63635 all phecode
791 Gangrene Symptoms 0.942 0.865 – 1.03 0.165 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1.07 0.865 – 1.32 0.542 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.954 0.805 – 1.13 0.59 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 0.994 0.912 – 1.08 0.899 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.1 0.912 – 1.33 0.316 120 1198 all phecode
797 Shock Symptoms 0.862 0.74 – 1.01 0.059 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 0.897 0.74 – 1.09 0.271 102 1020 all phecode
798 Malaise and fatigue Symptoms 1.01 0.973 – 1.05 0.638 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 1 0.92 – 1.09 0.977 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 0.984 0.96 – 1.01 0.187 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.999 0.952 – 1.05 0.958 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.866 0.746 – 1 0.058 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.939 0.899 – 0.98 0.00406 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 0.941 0.875 – 1.01 0.101 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.991 0.949 – 1.03 0.676 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 0.958 0.914 – 1 0.0792 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.99 0.917 – 1.07 0.805 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 0.979 0.957 – 1 0.0649 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 0.985 0.937 – 1.04 0.546 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.98 0.953 – 1.01 0.165 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.954 0.906 – 1 0.0759 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 1.01 0.971 – 1.04 0.724 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.996 0.942 – 1.05 0.885 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 1.05 0.974 – 1.13 0.203 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.992 0.937 – 1.05 0.796 1300 12998 all phecode
817 Concussion Injuries & Poisonings 0.924 0.812 – 1.05 0.226 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.935 0.855 – 1.02 0.138 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.975 0.939 – 1.01 0.179 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 0.926 0.882 – 0.972 0.00194 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 1 0.957 – 1.05 0.959 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 0.993 0.977 – 1.01 0.4 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 0.933 0.855 – 1.02 0.124 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 1.03 0.938 – 1.13 0.529 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.982 0.955 – 1.01 0.206 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.944 0.802 – 1.11 0.492 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 0.994 0.907 – 1.09 0.904 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.994 0.947 – 1.04 0.806 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.03 0.972 – 1.09 0.3 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.03 0.991 – 1.07 0.143 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 0.997 0.962 – 1.03 0.882 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 0.786 0.625 – 0.99 0.0411 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.988 0.954 – 1.02 0.486 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.05 0.922 – 1.18 0.487 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.992 0.854 – 1.15 0.916 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.974 0.938 – 1.01 0.173 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.974 0.849 – 1.12 0.71 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 1.09 0.857 – 1.39 0.479 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 0.998 0.966 – 1.03 0.901 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.98 0.744 – 1.29 0.884 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.862 0.697 – 1.07 0.169 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.976 0.841 – 1.13 0.751 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 1 0.913 – 1.1 0.965 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 0.869 0.762 – 0.99 0.0353 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 0.922 0.793 – 1.07 0.289 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 0.853 0.727 – 1 0.0503 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 0.991 0.937 – 1.05 0.753 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 0.985 0.955 – 1.02 0.342 4260 42663 all phecode
916 Contusion Injuries & Poisonings 0.979 0.928 – 1.03 0.431 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 1.14 0.972 – 1.34 0.107 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.955 0.862 – 1.06 0.38 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 1.03 0.903 – 1.17 0.679 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.989 0.946 – 1.03 0.642 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.933 0.816 – 1.07 0.314 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.07 0.869 – 1.31 0.536 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.03 0.944 – 1.13 0.49 550 5509 all phecode
947 Urticaria Injuries & Poisonings 0.955 0.861 – 1.06 0.389 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 1.07 0.963 – 1.19 0.205 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.07 0.963 – 1.18 0.218 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1 0.883 – 1.13 0.986 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.982 0.895 – 1.08 0.698 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 0.986 0.751 – 1.3 0.921 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.27 0.984 – 1.65 0.0666 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.994 0.979 – 1.01 0.464 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.993 0.977 – 1.01 0.406 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.05 0.951 – 1.17 0.316 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.03 0.963 – 1.11 0.361 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.958 0.862 – 1.06 0.427 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 0.958 0.861 – 1.07 0.434 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.05 0.91 – 1.2 0.524 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.962 0.855 – 1.08 0.517 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.932 0.827 – 1.05 0.245 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.02 0.993 – 1.05 0.147 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.987 0.929 – 1.05 0.678 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.952 0.868 – 1.04 0.302 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.07 0.968 – 1.19 0.179 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.978 0.894 – 1.07 0.633 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.959 0.881 – 1.04 0.338 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.02 0.972 – 1.07 0.453 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.03 0.887 – 1.2 0.696 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.03 0.905 – 1.17 0.678 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.09 0.866 – 1.36 0.473 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 0.857 0.706 – 1.04 0.118 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.918 0.757 – 1.11 0.39 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.2 0.92 – 1.57 0.177 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.02 0.777 – 1.35 0.873 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.05 0.916 – 1.2 0.486 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.03 0.955 – 1.12 0.422 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.05 0.911 – 1.21 0.5 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.11 0.857 – 1.44 0.429 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 0.986 0.809 – 1.2 0.885 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 1.12 0.913 – 1.36 0.285 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.992 0.798 – 1.23 0.944 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 1.02 0.98 – 1.06 0.374 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.01 0.972 – 1.05 0.643 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 1.01 0.972 – 1.05 0.643 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 0.976 0.95 – 1 0.0797 5538 63928 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 0.973 0.926 – 1.02 0.286 1663 19453 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.995 0.889 – 1.11 0.931 316 4512 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 0.966 0.884 – 1.05 0.434 514 6251 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.01 0.727 – 1.39 0.971 32 412 exclusion phecode
010 Tuberculosis Infectious Diseases 0.966 0.793 – 1.18 0.728 100 1154 exclusion phecode
038 Septicemia Infectious Diseases 0.981 0.939 – 1.02 0.385 2126 29197 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 0.98 0.887 – 1.08 0.683 415 5900 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 0.941 0.827 – 1.07 0.358 227 3457 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 0.955 0.932 – 0.978 0.000183 6955 85937 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 0.892 0.85 – 0.936 2.96e-06 1679 22196 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 0.952 0.893 – 1.02 0.137 976 11987 exclusion phecode
041.4 E. coli Infectious Diseases 0.946 0.899 – 0.996 0.0341 1520 19569 exclusion phecode
053 Herpes zoster Infectious Diseases 1.05 0.918 – 1.21 0.461 225 2821 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.35 1.02 – 1.79 0.0364 57 644 exclusion phecode
054 Herpes simplex Infectious Diseases 1.02 0.861 – 1.21 0.817 141 1606 exclusion phecode
070 Viral hepatitis Infectious Diseases 0.958 0.857 – 1.07 0.444 323 4477 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.03 0.768 – 1.38 0.847 48 549 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 0.909 0.732 – 1.13 0.386 73 968 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 0.892 0.75 – 1.06 0.193 132 2012 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.06 0.89 – 1.26 0.513 140 2057 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 0.967 0.848 – 1.1 0.62 224 3107 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.919 0.736 – 1.15 0.459 73 1099 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.929 0.726 – 1.19 0.557 59 878 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.988 0.914 – 1.07 0.749 706 7578 exclusion phecode
079 Viral infection Infectious Diseases 1 0.957 – 1.05 0.902 1923 21181 exclusion phecode
079.1 Varicella infection Infectious Diseases 1.08 0.803 – 1.46 0.605 46 518 exclusion phecode
080 Postoperative infection Infectious Diseases 0.963 0.926 – 1 0.0579 2675 32311 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 0.926 0.877 – 0.977 0.00505 1363 17494 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 1.05 0.767 – 1.43 0.772 45 535 exclusion phecode
1000 Burns Injuries & Poisonings 0.998 0.899 – 1.11 0.969 381 4263 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 0.942 0.879 – 1.01 0.0916 822 8739 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 0.965 0.933 – 0.998 0.0405 3520 39155 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 0.977 0.846 – 1.13 0.755 191 2193 exclusion phecode
1005 Other symptoms Injuries & Poisonings 0.992 0.927 – 1.06 0.826 863 10313 exclusion phecode
1006 Crushing injury Injuries & Poisonings 0.992 0.852 – 1.16 0.922 176 1821 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 1.05 0.902 – 1.22 0.535 178 1913 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.03 0.95 – 1.11 0.526 707 7313 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 0.984 0.958 – 1.01 0.247 5883 62296 exclusion phecode
1010 Other tests Injuries & Poisonings 1 0.968 – 1.03 0.992 3788 42750 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.986 0.959 – 1.01 0.29 5585 64404 exclusion phecode
1012 Late effect Injuries & Poisonings 0.873 0.697 – 1.09 0.235 76 764 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 0.918 0.797 – 1.06 0.236 199 2244 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.97 0.735 – 1.28 0.83 53 489 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 1.01 0.973 – 1.05 0.54 2671 31277 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 0.986 0.967 – 1.01 0.161 10738 116961 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.953 0.814 – 1.12 0.555 161 1992 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.948 0.808 – 1.11 0.511 157 1957 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.03 0.769 – 1.38 0.846 47 532 exclusion phecode
110.12 Althete's foot Infectious Diseases 0.966 0.773 – 1.21 0.76 77 994 exclusion phecode
112 Candidiasis Infectious Diseases 0.965 0.912 – 1.02 0.211 1280 15203 exclusion phecode
117 Mycoses Infectious Diseases 0.891 0.757 – 1.05 0.164 142 1917 exclusion phecode
117.4 Aspergillosis Infectious Diseases 0.907 0.735 – 1.12 0.365 85 1129 exclusion phecode
130 Spirochetal infection Infectious Diseases 1.01 0.78 – 1.32 0.913 54 603 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 0.987 0.731 – 1.33 0.932 44 522 exclusion phecode
134 Helminthiases Infectious Diseases 0.916 0.741 – 1.13 0.415 85 996 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 0.907 0.715 – 1.15 0.418 70 838 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.877 0.735 – 1.05 0.145 124 1464 exclusion phecode
145 Cancer of mouth Neoplasms 1.07 0.972 – 1.19 0.16 440 4516 exclusion phecode
145.2 Cancer of tongue Neoplasms 1.16 1.01 – 1.34 0.0401 217 2145 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.846 0.666 – 1.08 0.172 68 791 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1.05 0.748 – 1.48 0.775 37 369 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.1 0.988 – 1.22 0.0833 392 4321 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.12 0.956 – 1.32 0.156 170 1800 exclusion phecode
149.4 Cancer of larynx Neoplasms 1.05 0.882 – 1.24 0.609 140 1718 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.05 0.772 – 1.43 0.747 40 382 exclusion phecode
150 Cancer of esophagus Neoplasms 1.07 0.972 – 1.18 0.161 441 4965 exclusion phecode
151 Cancer of stomach Neoplasms 1.01 0.904 – 1.13 0.864 331 3675 exclusion phecode
153 Colorectal cancer Neoplasms 0.992 0.956 – 1.03 0.675 2982 31087 exclusion phecode
153.2 Colon cancer Neoplasms 0.979 0.936 – 1.02 0.357 2015 20964 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 1.02 0.963 – 1.07 0.546 1419 14778 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.969 0.848 – 1.11 0.639 220 2702 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.988 0.783 – 1.25 0.922 69 1024 exclusion phecode
157 Pancreatic cancer Neoplasms 1.05 0.949 – 1.17 0.332 398 4402 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.994 0.92 – 1.07 0.878 686 7382 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1.02 0.983 – 1.05 0.325 3553 37731 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.948 0.799 – 1.12 0.539 130 1326 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1.04 0.872 – 1.25 0.647 131 1394 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.981 0.817 – 1.18 0.841 122 1346 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.969 0.708 – 1.32 0.842 41 409 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1 0.954 – 1.05 0.915 1593 18688 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 0.953 0.901 – 1.01 0.0977 1233 14797 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 0.923 0.819 – 1.04 0.193 295 3027 exclusion phecode
170.1 Bone cancer Neoplasms 0.802 0.648 – 0.992 0.0423 84 899 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 0.976 0.849 – 1.12 0.736 225 2294 exclusion phecode
172 Skin cancer Neoplasms 1.01 0.989 – 1.03 0.363 9327 92779 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 1.04 0.99 – 1.09 0.121 1928 19087 exclusion phecode
172.11 Melanomas of skin Neoplasms 1.04 0.989 – 1.09 0.131 1951 19315 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1.01 0.985 – 1.03 0.476 7542 74823 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 0.919 0.832 – 1.01 0.0923 406 4415 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.06 0.881 – 1.27 0.542 128 1321 exclusion phecode
174 Breast cancer Neoplasms 0.996 0.975 – 1.02 0.678 9487 97258 exclusion phecode
174.1 Breast cancer [female] Neoplasms 0.996 0.975 – 1.02 0.695 9353 95789 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.999 0.977 – 1.02 0.914 8789 90219 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.03 0.832 – 1.28 0.781 93 905 exclusion phecode
175 Acquired absence of breast Neoplasms 0.999 0.951 – 1.05 0.956 1768 18613 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.03 0.979 – 1.08 0.253 1779 18031 exclusion phecode
180.1 Cervical cancer Neoplasms 0.991 0.862 – 1.14 0.901 214 2176 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.05 0.995 – 1.1 0.0743 1703 17213 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 1.02 0.953 – 1.1 0.53 847 9520 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.02 0.952 – 1.09 0.623 1010 10505 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.03 0.955 – 1.12 0.422 715 7284 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.03 0.955 – 1.12 0.411 693 7046 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 1.05 0.908 – 1.21 0.529 219 2371 exclusion phecode
185 Cancer of prostate Neoplasms 0.983 0.951 – 1.02 0.321 3690 35865 exclusion phecode
187 Cancer of other male genital organs Neoplasms 0.94 0.839 – 1.05 0.283 304 3153 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 0.679 0.503 – 0.917 0.0115 40 438 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.986 0.855 – 1.14 0.843 199 2112 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.07 0.844 – 1.35 0.583 75 735 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.982 0.94 – 1.03 0.41 2136 27012 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.952 0.864 – 1.05 0.317 403 7221 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.954 0.863 – 1.05 0.351 383 6951 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.972 0.684 – 1.38 0.873 31 434 exclusion phecode
189.2 Cancer of bladder Neoplasms 0.986 0.934 – 1.04 0.621 1356 15398 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.991 0.935 – 1.05 0.767 1195 13676 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.22 0.935 – 1.59 0.143 58 938 exclusion phecode
190 Cancer of eye Neoplasms 1.18 0.972 – 1.43 0.0942 122 1233 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 1.04 0.942 – 1.14 0.461 471 4848 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 1.02 0.921 – 1.14 0.679 389 3944 exclusion phecode
191.11 Cancer of brain Neoplasms 1.01 0.909 – 1.13 0.818 362 3669 exclusion phecode
193 Thyroid cancer Neoplasms 0.848 0.748 – 0.961 0.00978 234 2652 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 1.12 0.861 – 1.47 0.389 58 701 exclusion phecode
195 Cancer, suspected or other Neoplasms 1.01 0.987 – 1.03 0.524 11114 116438 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 1.01 0.989 – 1.03 0.364 10621 111911 exclusion phecode
197 Chemotherapy Neoplasms 0.985 0.968 – 1 0.0915 14014 156042 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 0.991 0.966 – 1.02 0.516 6170 67750 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.987 0.954 – 1.02 0.449 3642 38998 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 1.02 0.962 – 1.07 0.559 1380 15988 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.981 0.92 – 1.05 0.549 1009 11039 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 0.983 0.935 – 1.03 0.502 1657 18449 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 1.03 0.939 – 1.12 0.558 527 6027 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 0.951 0.899 – 1.01 0.078 1291 14889 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 1.22 1.01 – 1.49 0.0442 119 1353 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 0.965 0.9 – 1.04 0.321 841 10306 exclusion phecode
199.4 Neurofibromatosis Neoplasms 0.929 0.682 – 1.27 0.64 39 706 exclusion phecode
200 Myeloproliferative disease Neoplasms 0.879 0.804 – 0.961 0.00468 480 6747 exclusion phecode
200.1 Polycythemia vera Neoplasms 0.842 0.724 – 0.98 0.0262 162 2584 exclusion phecode
201 Hodgkin's disease Neoplasms 1.07 0.91 – 1.26 0.409 160 1976 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.969 0.917 – 1.02 0.266 1288 15846 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.959 0.901 – 1.02 0.189 1012 12512 exclusion phecode
202.21 Nodular lymphoma Neoplasms 0.825 0.725 – 0.94 0.00373 220 2507 exclusion phecode
202.24 Large cell lymphoma Neoplasms 0.909 0.816 – 1.01 0.0814 328 4022 exclusion phecode
204 Leukemia Neoplasms 0.957 0.896 – 1.02 0.193 926 11320 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 0.961 0.859 – 1.07 0.484 317 3872 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.09 0.756 – 1.57 0.649 34 413 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.962 0.853 – 1.09 0.529 270 3393 exclusion phecode
204.2 Myeloid leukemia Neoplasms 0.93 0.825 – 1.05 0.235 271 3228 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 0.898 0.778 – 1.04 0.141 182 2296 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.926 0.761 – 1.13 0.44 103 1010 exclusion phecode
204.4 Multiple myeloma Neoplasms 1.03 0.91 – 1.16 0.664 287 3744 exclusion phecode
208 Benign neoplasm of colon Neoplasms 0.999 0.981 – 1.02 0.874 12795 134394 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.01 0.93 – 1.09 0.892 681 7213 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.962 0.93 – 0.995 0.0235 3571 37441 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.03 0.902 – 1.18 0.655 234 2505 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.02 0.886 – 1.16 0.83 244 2393 exclusion phecode
214 Lipoma Neoplasms 0.98 0.951 – 1.01 0.197 4392 45251 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.979 0.945 – 1.01 0.236 3277 33835 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 0.93 0.867 – 0.997 0.0415 820 8233 exclusion phecode
216 Benign neoplasm of skin Neoplasms 0.993 0.966 – 1.02 0.609 5724 57581 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.986 0.895 – 1.09 0.783 435 4529 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 0.979 0.887 – 1.08 0.676 409 4246 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 1 0.982 – 1.03 0.7 8074 81251 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 1.01 0.984 – 1.03 0.548 8240 82633 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.06 0.933 – 1.2 0.371 269 2832 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.997 0.937 – 1.06 0.915 1120 11458 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.14 0.975 – 1.34 0.1 173 1750 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 0.773 0.636 – 0.94 0.01 94 1038 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 0.84 0.692 – 1.02 0.0783 100 1152 exclusion phecode
224 Benign neoplasm of eye Neoplasms 0.798 0.644 – 0.99 0.0398 78 954 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.729 0.538 – 0.987 0.0406 37 458 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 1.07 0.982 – 1.17 0.12 563 5999 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 1.06 0.966 – 1.16 0.23 528 5694 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 1.17 0.846 – 1.63 0.336 43 455 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 1.17 0.999 – 1.36 0.0514 196 2039 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.943 0.866 – 1.03 0.179 548 6287 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.947 0.786 – 1.14 0.563 106 1354 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 0.904 0.795 – 1.03 0.122 237 2662 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.954 0.827 – 1.1 0.516 204 2262 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.03 0.97 – 1.1 0.318 1141 11659 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 0.964 0.919 – 1.01 0.132 1842 18187 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 0.965 0.874 – 1.07 0.486 414 4535 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1.05 0.979 – 1.14 0.161 779 8411 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 0.928 0.833 – 1.03 0.172 357 3598 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 1.15 1.04 – 1.28 0.00534 451 5090 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.973 0.917 – 1.03 0.359 1162 13999 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 1.03 0.917 – 1.15 0.638 327 3632 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 0.962 0.749 – 1.24 0.765 57 715 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 1.09 0.878 – 1.36 0.425 95 1059 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 0.953 0.934 – 0.974 8.92e-06 9219 108660 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.947 0.879 – 1.02 0.159 700 8273 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.03 0.784 – 1.35 0.843 60 769 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.954 0.934 – 0.975 2.2e-05 8765 103937 exclusion phecode
245 Thyroiditis Endocrine/metabolic 1.07 0.923 – 1.23 0.382 201 2279 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 1.04 0.885 – 1.23 0.611 153 1716 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 1.06 0.892 – 1.25 0.53 145 1639 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 0.991 0.874 – 1.12 0.886 260 3014 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 0.978 0.959 – 0.997 0.0217 10925 131077 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 1.02 0.968 – 1.08 0.449 1489 19737 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 1.19 0.992 – 1.42 0.0609 140 1800 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.949 0.554 – 1.62 0.847 8 556 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.98 0.859 – 1.12 0.765 222 3357 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.09 0.829 – 1.43 0.543 51 1141 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.976 0.956 – 0.996 0.0185 9579 118577 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.979 0.756 – 1.27 0.869 61 768 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 0.944 0.659 – 1.35 0.752 25 1338 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.931 0.845 – 1.03 0.152 397 6711 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 0.946 0.813 – 1.1 0.473 164 3447 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 1.04 0.935 – 1.15 0.493 400 4888 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.01 0.867 – 1.18 0.883 172 1858 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 1.05 0.912 – 1.2 0.527 228 3014 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 1.09 0.884 – 1.35 0.411 104 1107 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.988 0.83 – 1.18 0.889 124 2404 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.97 0.895 – 1.05 0.466 596 9087 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.08 0.985 – 1.19 0.0994 451 6676 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.933 0.85 – 1.02 0.147 461 6281 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.954 0.864 – 1.05 0.347 417 5639 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.794 0.623 – 1.01 0.0618 59 1003 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.965 0.874 – 1.06 0.476 413 4880 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 0.982 0.819 – 1.18 0.847 122 1392 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.811 0.641 – 1.03 0.0804 61 699 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.974 0.824 – 1.15 0.753 143 1869 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.23 0.914 – 1.66 0.172 47 715 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.956 0.79 – 1.16 0.639 107 1033 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.979 0.876 – 1.09 0.714 337 4714 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 0.897 0.729 – 1.1 0.305 90 1352 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.915 0.695 – 1.2 0.526 52 805 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 0.898 0.653 – 1.24 0.509 38 549 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.946 0.816 – 1.1 0.46 185 2651 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.946 0.816 – 1.1 0.467 185 2645 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 0.966 0.835 – 1.12 0.646 204 2141 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.971 0.829 – 1.14 0.715 174 1876 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 0.932 0.758 – 1.15 0.501 87 1131 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.923 0.744 – 1.15 0.469 80 1064 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.906 0.7 – 1.17 0.453 55 752 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 1 0.822 – 1.23 0.963 102 1134 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.14 0.945 – 1.38 0.168 117 1414 exclusion phecode
260.1 Cachexia Endocrine/metabolic 0.877 0.612 – 1.26 0.473 27 340 exclusion phecode
260.6 Anorexia Endocrine/metabolic 1.03 0.936 – 1.12 0.589 494 5856 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 0.982 0.909 – 1.06 0.64 692 8706 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.985 0.894 – 1.09 0.764 440 5454 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.944 0.834 – 1.07 0.362 258 3312 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.868 0.636 – 1.19 0.374 36 575 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.04 0.881 – 1.23 0.644 152 1775 exclusion phecode
269 Proteinuria Endocrine/metabolic 0.918 0.783 – 1.08 0.297 158 2372 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.965 0.828 – 1.12 0.65 160 2051 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.956 0.808 – 1.13 0.598 134 1749 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 0.943 0.773 – 1.15 0.559 94 1263 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 1.04 0.801 – 1.35 0.772 55 764 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.06 0.762 – 1.47 0.734 36 475 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.939 0.775 – 1.14 0.518 109 1184 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.983 0.802 – 1.2 0.867 99 1039 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.99 0.976 – 1 0.194 20417 170572 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.991 0.976 – 1.01 0.208 20374 170389 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.988 0.974 – 1 0.126 18889 164486 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.02 0.729 – 1.41 0.928 38 411 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.984 0.794 – 1.22 0.88 84 1154 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.876 0.734 – 1.04 0.14 118 1442 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.913 0.869 – 0.959 0.000276 1596 24798 exclusion phecode
274.1 Gout Endocrine/metabolic 0.922 0.872 – 0.974 0.00392 1237 20817 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.931 0.708 – 1.22 0.61 51 735 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 0.879 0.794 – 0.972 0.0124 384 4360 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 0.878 0.79 – 0.976 0.0162 356 3988 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 0.92 0.868 – 0.975 0.00519 1172 14742 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.949 0.861 – 1.05 0.296 423 4588 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 0.852 0.743 – 0.977 0.0221 200 2573 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 0.896 0.827 – 0.971 0.00725 610 8470 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.901 0.736 – 1.1 0.312 100 1209 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 0.967 0.936 – 1 0.0488 3665 50343 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 0.943 0.903 – 0.985 0.00779 2110 28095 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 0.872 0.73 – 1.04 0.13 121 1585 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 0.967 0.909 – 1.03 0.29 1071 12445 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 0.885 0.794 – 0.987 0.0278 311 6533 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 0.932 0.868 – 1 0.0549 773 10104 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.03 0.939 – 1.13 0.522 470 7952 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1 0.911 – 1.11 0.933 420 7243 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 1.19 0.891 – 1.6 0.236 52 746 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 0.995 0.943 – 1.05 0.85 1409 19646 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 0.872 0.748 – 1.02 0.0809 151 3022 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.07 0.863 – 1.34 0.52 88 971 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 0.969 0.888 – 1.06 0.488 517 6497 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.06 0.931 – 1.21 0.368 238 2573 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.01 0.846 – 1.21 0.909 132 1611 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 0.89 0.595 – 1.33 0.569 26 367 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.916 0.892 – 0.94 6.61e-11 5600 79880 exclusion phecode
278.1 Obesity Endocrine/metabolic 0.915 0.891 – 0.939 5.26e-11 5501 78655 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 0.985 0.772 – 1.26 0.903 61 686 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.813 0.589 – 1.12 0.209 32 510 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.971 0.821 – 1.15 0.731 144 1853 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 0.969 0.81 – 1.16 0.725 121 1545 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.936 0.746 – 1.17 0.568 77 1012 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 0.962 0.821 – 1.13 0.633 164 1594 exclusion phecode
280 Iron deficiency anemias Hematopoietic 0.984 0.956 – 1.01 0.293 4717 56023 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.989 0.96 – 1.02 0.487 4497 53665 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.968 0.864 – 1.08 0.572 322 3555 exclusion phecode
281 Other deficiency anemia Hematopoietic 0.948 0.874 – 1.03 0.193 613 8034 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 0.951 0.876 – 1.03 0.229 593 7703 exclusion phecode
281.11 Pernicious anemia Hematopoietic 0.952 0.865 – 1.05 0.319 430 5434 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.929 0.761 – 1.13 0.466 103 1327 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 0.981 0.788 – 1.22 0.863 80 1277 exclusion phecode
281.9 Deficiency anemias Hematopoietic 0.826 0.547 – 1.25 0.364 23 369 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1.03 0.828 – 1.29 0.771 77 1087 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 1.11 0.789 – 1.57 0.544 33 406 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.952 0.704 – 1.29 0.747 42 618 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 0.883 0.69 – 1.13 0.323 59 972 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.932 0.701 – 1.24 0.626 45 730 exclusion phecode
284 Aplastic anemia Hematopoietic 0.864 0.755 – 0.988 0.0327 200 3051 exclusion phecode
285 Other anemias Hematopoietic 0.983 0.96 – 1.01 0.166 7059 87513 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.05 0.904 – 1.22 0.522 185 2064 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 0.898 0.8 – 1.01 0.0686 268 4887 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.899 0.793 – 1.02 0.0973 235 2923 exclusion phecode
286 Coagulation defects Hematopoietic 1.04 0.955 – 1.14 0.35 557 6766 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 1.09 0.966 – 1.23 0.163 317 3459 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 1.26 0.967 – 1.63 0.088 74 734 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.05 0.905 – 1.22 0.516 201 2233 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.05 0.772 – 1.44 0.738 38 460 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 0.721 0.523 – 0.995 0.0464 29 569 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.02 0.885 – 1.17 0.812 218 2823 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.936 0.875 – 1 0.055 868 11543 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.913 0.733 – 1.14 0.414 80 916 exclusion phecode
287.2 Allergic purpura Hematopoietic 0.973 0.696 – 1.36 0.875 30 395 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 0.957 0.892 – 1.03 0.222 812 10830 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1.03 0.896 – 1.18 0.676 214 2939 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.1 0.778 – 1.56 0.582 32 507 exclusion phecode
288 Diseases of white blood cells Hematopoietic 0.969 0.929 – 1.01 0.143 2279 27246 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 0.981 0.937 – 1.03 0.411 1930 22983 exclusion phecode
288.11 Neutropenia Hematopoietic 0.981 0.937 – 1.03 0.426 1937 23042 exclusion phecode
288.3 Eosinophilia Hematopoietic 0.713 0.536 – 0.948 0.0199 40 499 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.946 0.862 – 1.04 0.235 474 6221 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 1.05 0.895 – 1.22 0.569 164 2167 exclusion phecode
289.4 Lymphadenitis Hematopoietic 0.942 0.896 – 0.991 0.0208 1575 18736 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1.01 0.896 – 1.13 0.894 291 3627 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 0.92 0.777 – 1.09 0.335 133 2006 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 0.794 0.585 – 1.08 0.138 38 649 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.02 0.958 – 1.09 0.527 1010 12458 exclusion phecode
290.1 Dementias Mental Disorders 1.01 0.928 – 1.11 0.779 540 6269 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 1 0.881 – 1.14 0.987 252 2750 exclusion phecode
290.16 Vascular dementia Mental Disorders 0.98 0.804 – 1.2 0.842 99 1219 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.08 0.963 – 1.21 0.186 328 4252 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.9 0.672 – 1.21 0.48 42 558 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.999 0.911 – 1.09 0.975 499 6087 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.935 0.76 – 1.15 0.522 95 1045 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 1.05 0.894 – 1.24 0.543 163 1978 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 0.968 0.853 – 1.1 0.62 255 3192 exclusion phecode
292 Neurological disorders Mental Disorders 0.958 0.922 – 0.995 0.0269 2712 31905 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.97 0.908 – 1.04 0.371 906 10596 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 1.04 0.85 – 1.28 0.68 99 1299 exclusion phecode
292.3 Memory loss Mental Disorders 0.97 0.884 – 1.06 0.522 469 4916 exclusion phecode
292.4 Altered mental status Mental Disorders 0.966 0.912 – 1.02 0.235 1211 14671 exclusion phecode
292.6 Hallucinations Mental Disorders 0.928 0.799 – 1.08 0.327 171 2166 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 0.957 0.907 – 1.01 0.102 1419 15198 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.03 0.945 – 1.12 0.53 605 6623 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 1.02 0.929 – 1.12 0.68 493 6382 exclusion phecode
295.1 Schizophrenia Mental Disorders 1.01 0.903 – 1.13 0.854 326 4364 exclusion phecode
295.2 Paranoid disorders Mental Disorders 0.993 0.823 – 1.2 0.942 111 1363 exclusion phecode
295.3 Psychosis Mental Disorders 1.08 0.881 – 1.33 0.452 101 1317 exclusion phecode
296 Mood disorders Mental Disorders 0.961 0.939 – 0.983 0.000508 8082 94942 exclusion phecode
296.1 Bipolar Mental Disorders 0.935 0.863 – 1.01 0.0955 632 8089 exclusion phecode
296.2 Depression Mental Disorders 0.962 0.94 – 0.984 0.001 7697 90087 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.01 0.881 – 1.15 0.903 228 2742 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.03 0.899 – 1.19 0.644 208 2413 exclusion phecode
300 Anxiety disorders Mental Disorders 0.977 0.949 – 1.01 0.135 4624 51851 exclusion phecode
300.1 Anxiety disorder Mental Disorders 0.981 0.951 – 1.01 0.236 4282 47836 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 0.995 0.82 – 1.21 0.956 109 1153 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 0.94 0.856 – 1.03 0.19 474 5403 exclusion phecode
300.13 Phobia Mental Disorders 1.01 0.901 – 1.13 0.857 326 3766 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.15 0.935 – 1.43 0.181 97 1080 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 0.781 0.572 – 1.07 0.121 37 419 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 0.948 0.765 – 1.17 0.626 86 965 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.832 0.666 – 1.04 0.106 80 891 exclusion phecode
301 Personality disorders Mental Disorders 0.866 0.754 – 0.994 0.0413 203 2700 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 0.848 0.676 – 1.06 0.156 74 1010 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 0.997 0.85 – 1.17 0.973 162 1890 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.934 0.835 – 1.05 0.238 327 3543 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.984 0.863 – 1.12 0.815 252 2625 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.889 0.715 – 1.11 0.29 82 960 exclusion phecode
304 Adjustment reaction Mental Disorders 1 0.868 – 1.16 0.957 202 2288 exclusion phecode
305.2 Eating disorder Mental Disorders 1 0.787 – 1.28 0.985 73 763 exclusion phecode
306 Other mental disorder Mental Disorders 0.977 0.962 – 0.993 0.00407 17030 167354 exclusion phecode
306.9 Tension headache Mental Disorders 0.979 0.851 – 1.13 0.771 218 2489 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 1.13 0.854 – 1.49 0.396 54 593 exclusion phecode
313.3 Autism Mental Disorders 0.855 0.63 – 1.16 0.317 39 409 exclusion phecode
315 Develomental delays and disorders Mental Disorders 0.961 0.834 – 1.11 0.587 200 2513 exclusion phecode
315.1 Learning disorder Mental Disorders 1.1 0.878 – 1.39 0.399 83 1248 exclusion phecode
315.2 Speech and language disorder Mental Disorders 1.06 0.794 – 1.43 0.677 50 615 exclusion phecode
316 Substance addiction and disorders Mental Disorders 0.974 0.94 – 1.01 0.13 3375 39026 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1 0.707 – 1.42 0.988 31 449 exclusion phecode
317 Alcohol-related disorders Mental Disorders 0.986 0.965 – 1.01 0.207 8591 92459 exclusion phecode
317.1 Alcoholism Mental Disorders 0.993 0.967 – 1.02 0.587 6050 64215 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 0.981 0.894 – 1.08 0.678 450 6050 exclusion phecode
318 Tobacco use disorder Mental Disorders 0.956 0.938 – 0.975 4.55e-06 11090 136722 exclusion phecode
320 Meningitis Neurological 1.03 0.917 – 1.16 0.601 314 3432 exclusion phecode
323 Encephalitis Neurological 0.969 0.851 – 1.1 0.642 242 2561 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 0.85 0.663 – 1.09 0.201 62 590 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 0.887 0.767 – 1.03 0.108 186 2017 exclusion phecode
327 Sleep disorders Neurological 0.893 0.831 – 0.959 0.00191 753 8299 exclusion phecode
327.3 Sleep apnea Neurological 0.965 0.927 – 1 0.0798 2509 31613 exclusion phecode
327.4 Insomnia Neurological 0.931 0.77 – 1.13 0.459 106 1206 exclusion phecode
327.41 Organic or persistent insomnia Neurological 0.882 0.72 – 1.08 0.226 89 1012 exclusion phecode
331 Other cerebral degenerations Neurological 0.996 0.922 – 1.08 0.92 688 7941 exclusion phecode
331.1 Hydrocephalus Neurological 1.03 0.92 – 1.16 0.578 320 3620 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 0.921 0.812 – 1.04 0.198 245 2859 exclusion phecode
332 Parkinson's disease Neurological 0.935 0.867 – 1.01 0.0819 696 7283 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 0.917 0.843 – 0.998 0.0444 563 6369 exclusion phecode
333.1 Essential tremor Neurological 0.835 0.698 – 0.998 0.0473 119 1443 exclusion phecode
333.2 Myoclonus Neurological 0.848 0.661 – 1.09 0.197 65 700 exclusion phecode
333.4 Torsion dystonia Neurological 1.06 0.904 – 1.25 0.459 169 1872 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 0.98 0.923 – 1.04 0.516 1142 12828 exclusion phecode
334.1 Spinocerebellar disease Neurological 0.91 0.715 – 1.16 0.447 65 836 exclusion phecode
334.2 Anterior horn cell disease Neurological 0.887 0.755 – 1.04 0.144 159 1626 exclusion phecode
335 Multiple sclerosis Neurological 0.997 0.934 – 1.06 0.926 1001 10396 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 0.927 0.791 – 1.09 0.348 157 1874 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 1.1 0.783 – 1.54 0.585 36 467 exclusion phecode
338 Pain Neurological 0.888 0.811 – 0.973 0.0109 465 5734 exclusion phecode
338.1 Acute pain Neurological 0.924 0.811 – 1.05 0.238 226 2898 exclusion phecode
338.2 Chronic pain Neurological 0.889 0.784 – 1.01 0.0688 242 2934 exclusion phecode
339 Other headache syndromes Neurological 0.985 0.958 – 1.01 0.286 5457 59083 exclusion phecode
340 Migraine Neurological 1.02 0.971 – 1.06 0.488 2104 22427 exclusion phecode
340.1 Migrain with aura Neurological 1.12 0.946 – 1.33 0.187 154 1692 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.03 0.887 – 1.2 0.693 196 1993 exclusion phecode
342 Hemiplegia Neurological 0.932 0.869 – 0.999 0.0457 811 10529 exclusion phecode
343 Infantile cerebral palsy Neurological 1.22 0.983 – 1.51 0.0712 101 1092 exclusion phecode
344 Other paralytic syndromes Neurological 0.933 0.846 – 1.03 0.166 415 4841 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.997 0.963 – 1.03 0.884 3449 36984 exclusion phecode
345.1 Epilepsy Neurological 1 0.92 – 1.09 0.995 600 6422 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 0.917 0.82 – 1.03 0.131 313 3237 exclusion phecode
345.12 Partial epilepsy Neurological 1 0.868 – 1.15 0.987 200 2113 exclusion phecode
345.3 Convulsions Neurological 1 0.95 – 1.05 0.971 1513 16471 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.953 0.778 – 1.17 0.641 91 1064 exclusion phecode
348 Other conditions of brain Neurological 0.936 0.853 – 1.03 0.162 469 5731 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 0.969 0.825 – 1.14 0.698 159 2021 exclusion phecode
348.4 Cerebral cysts Neurological 0.893 0.729 – 1.09 0.275 97 1023 exclusion phecode
348.7 Coma Neurological 1.01 0.883 – 1.15 0.917 244 2540 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 0.909 0.773 – 1.07 0.245 147 1803 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 0.988 0.873 – 1.12 0.851 266 2780 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.955 0.835 – 1.09 0.507 221 2482 exclusion phecode
350 Abnormal movement Neurological 0.954 0.907 – 1 0.0724 1558 18808 exclusion phecode
350.1 Abnormal involuntary movements Neurological 0.963 0.882 – 1.05 0.406 540 6480 exclusion phecode
350.2 Abnormality of gait Neurological 0.956 0.894 – 1.02 0.19 884 10945 exclusion phecode
350.3 Lack of coordination Neurological 0.967 0.845 – 1.11 0.627 223 2634 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.08 0.789 – 1.49 0.62 39 397 exclusion phecode
351 Other peripheral nerve disorders Neurological 0.999 0.977 – 1.02 0.942 8509 92624 exclusion phecode
352 Disorders of other cranial nerves Neurological 0.972 0.908 – 1.04 0.4 903 9985 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.04 0.926 – 1.16 0.524 319 3438 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 0.987 0.906 – 1.08 0.763 565 6376 exclusion phecode
353 Nerve root and plexus disorders Neurological 0.987 0.913 – 1.07 0.738 692 8200 exclusion phecode
353.1 Nerve plexus lesions Neurological 1.09 0.86 – 1.37 0.49 79 883 exclusion phecode
353.2 Nerve root lesions Neurological 0.929 0.675 – 1.28 0.65 36 413 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.841 0.689 – 1.03 0.0906 93 1075 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 0.877 0.817 – 0.942 0.000301 759 9463 exclusion phecode
358 Myoneural disorders Neurological 0.981 0.815 – 1.18 0.835 113 1447 exclusion phecode
358.1 Myasthenia gravis Neurological 0.942 0.779 – 1.14 0.534 105 1336 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.894 0.789 – 1.01 0.0787 245 3358 exclusion phecode
359.1 Muscular dystrophies Neurological 0.953 0.746 – 1.22 0.697 61 888 exclusion phecode
359.2 Myopathy Neurological 0.854 0.741 – 0.985 0.0301 190 2586 exclusion phecode
360 Disorders of the globe Sense Organs 1.04 0.908 – 1.2 0.554 226 2287 exclusion phecode
360.2 Progressive myopia Sense Organs 1.04 0.885 – 1.21 0.662 167 1721 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.992 0.95 – 1.03 0.699 2307 22703 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 1 0.939 – 1.07 0.949 980 9779 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 1.15 0.829 – 1.59 0.405 40 490 exclusion phecode
362 Other retinal disorders Sense Organs 0.977 0.938 – 1.02 0.271 2379 25973 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.949 0.9 – 1 0.058 1374 14566 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.951 0.901 – 1 0.0646 1372 14540 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.913 0.757 – 1.1 0.342 106 1132 exclusion phecode
362.31 Separation of retinal layers Sense Organs 0.923 0.736 – 1.16 0.487 76 683 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 0.964 0.88 – 1.06 0.427 475 5694 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 1.13 0.937 – 1.36 0.205 126 1302 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.41 1.05 – 1.89 0.0226 61 584 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.1 0.876 – 1.38 0.416 79 801 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.04 0.853 – 1.27 0.686 104 1221 exclusion phecode
363.3 Chorioretinal scars Sense Organs 0.955 0.685 – 1.33 0.784 34 506 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.976 0.887 – 1.08 0.627 440 4556 exclusion phecode
364.1 Corneal opacity Sense Organs 0.917 0.706 – 1.19 0.513 58 650 exclusion phecode
364.2 Corneal edema Sense Organs 1.1 0.802 – 1.51 0.553 43 547 exclusion phecode
364.4 Corneal degenerations Sense Organs 0.867 0.736 – 1.02 0.0865 149 1459 exclusion phecode
364.41 Keratoconus Sense Organs 0.927 0.731 – 1.18 0.532 66 667 exclusion phecode
364.5 Corneal dystrophy Sense Organs 1.05 0.878 – 1.25 0.608 136 1407 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 1.05 0.831 – 1.34 0.662 69 706 exclusion phecode
365 Glaucoma Sense Organs 0.984 0.947 – 1.02 0.404 2838 29671 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 0.98 0.907 – 1.06 0.616 674 6777 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.979 0.906 – 1.06 0.584 670 6746 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.959 0.875 – 1.05 0.368 477 4805 exclusion phecode
366 Cataract Sense Organs 0.988 0.969 – 1.01 0.184 12277 115766 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.973 0.724 – 1.31 0.854 42 517 exclusion phecode
366.2 Senile cataract Sense Organs 0.982 0.955 – 1.01 0.224 5021 54573 exclusion phecode
366.3 Traumatic cataract Sense Organs 0.844 0.672 – 1.06 0.145 69 681 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.999 0.949 – 1.05 0.97 1610 16847 exclusion phecode
367.1 Myopia Sense Organs 0.967 0.903 – 1.03 0.329 880 8778 exclusion phecode
367.2 Astigmatism Sense Organs 0.978 0.815 – 1.17 0.808 124 1340 exclusion phecode
367.8 Hypermetropia Sense Organs 1.01 0.857 – 1.18 0.933 162 1737 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.05 0.955 – 1.16 0.3 439 4993 exclusion phecode
368 Visual disturbances Sense Organs 0.943 0.9 – 0.987 0.0124 1896 21389 exclusion phecode
368.1 Amblyopia Sense Organs 1.01 0.905 – 1.14 0.804 320 3683 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.947 0.862 – 1.04 0.262 454 5275 exclusion phecode
368.3 Anisometropia Sense Organs 0.875 0.724 – 1.06 0.165 103 1123 exclusion phecode
368.4 Visual field defects Sense Organs 0.908 0.791 – 1.04 0.168 209 2315 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 0.862 0.782 – 0.951 0.00294 395 4538 exclusion phecode
369 Infection of the eye Sense Organs 0.911 0.818 – 1.01 0.089 353 4013 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.978 0.774 – 1.24 0.855 72 887 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 0.9 0.756 – 1.07 0.237 131 1554 exclusion phecode
370 Keratitis Sense Organs 0.945 0.816 – 1.09 0.449 190 2088 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.986 0.806 – 1.21 0.887 97 1021 exclusion phecode
371 Inflammation of the eye Sense Organs 0.966 0.925 – 1.01 0.119 2192 22200 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.931 0.832 – 1.04 0.211 307 3471 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 0.97 0.924 – 1.02 0.228 1752 17237 exclusion phecode
372 Disorders of conjunctiva Sense Organs 0.971 0.889 – 1.06 0.51 529 5408 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.998 0.966 – 1.03 0.909 3803 40161 exclusion phecode
374.1 Ectropion or entropion Sense Organs 1.05 0.965 – 1.14 0.268 641 6965 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.996 0.939 – 1.06 0.896 1222 12800 exclusion phecode
375 Disorders of lacrimal system Sense Organs 1.01 0.954 – 1.06 0.848 1523 15626 exclusion phecode
375.2 Epiphora Sense Organs 1.01 0.932 – 1.1 0.787 636 6274 exclusion phecode
376 Disorders of the orbit Sense Organs 1.07 0.805 – 1.42 0.649 52 610 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.01 0.883 – 1.16 0.877 228 2651 exclusion phecode
377.1 Optic atrophy Sense Organs 0.96 0.696 – 1.33 0.806 34 417 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.06 0.852 – 1.33 0.588 87 959 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.04 0.972 – 1.11 0.263 958 10370 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 1.08 0.994 – 1.17 0.0707 651 6823 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.06 0.88 – 1.27 0.557 125 1501 exclusion phecode
378.5 Paralytic strabismus Sense Organs 0.875 0.751 – 1.02 0.0897 171 1962 exclusion phecode
379 Other disorders of eye Sense Organs 1.01 0.965 – 1.05 0.755 2311 25287 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.988 0.923 – 1.06 0.732 875 9435 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 1.01 0.952 – 1.08 0.694 1086 12029 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 0.91 0.686 – 1.21 0.51 49 522 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.971 0.859 – 1.1 0.636 262 2833 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.01 0.824 – 1.23 0.954 102 1236 exclusion phecode
380 Disorders of external ear Sense Organs 0.984 0.894 – 1.08 0.742 448 4445 exclusion phecode
380.1 Otitis externa Sense Organs 0.924 0.828 – 1.03 0.16 342 3761 exclusion phecode
380.4 Impacted cerumen Sense Organs 1.02 0.896 – 1.15 0.808 250 2575 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.02 0.964 – 1.07 0.533 1414 15684 exclusion phecode
381.1 Otitis media Sense Organs 1.02 0.959 – 1.08 0.544 1156 12856 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.99 0.909 – 1.08 0.812 553 6278 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 1.04 0.872 – 1.24 0.674 135 1457 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.895 0.743 – 1.08 0.244 113 1243 exclusion phecode
381.9 Otorrhea Sense Organs 1.06 0.913 – 1.24 0.429 185 2030 exclusion phecode
382 Otalgia Sense Organs 0.925 0.807 – 1.06 0.266 219 2306 exclusion phecode
383 Otosclerosis Sense Organs 0.962 0.843 – 1.1 0.572 232 2353 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 1.04 0.968 – 1.11 0.307 919 9595 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 1.03 0.955 – 1.11 0.428 732 7653 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.976 0.893 – 1.07 0.584 527 5736 exclusion phecode
385.3 Cholesteatoma Sense Organs 1 0.903 – 1.11 0.998 400 4423 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.93 0.797 – 1.09 0.361 170 1806 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 0.93 0.877 – 0.987 0.0161 1156 12518 exclusion phecode
386.1 Meniere's disease Sense Organs 0.89 0.803 – 0.987 0.0273 369 4126 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 0.927 0.815 – 1.05 0.249 250 2655 exclusion phecode
386.3 Labyrinthitis Sense Organs 0.966 0.884 – 1.05 0.441 515 5560 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.957 0.922 – 0.994 0.0227 2850 32587 exclusion phecode
388 Other disorders of ear Sense Organs 0.881 0.747 – 1.04 0.135 141 1463 exclusion phecode
389 Hearing loss Sense Organs 0.987 0.949 – 1.03 0.52 2628 29264 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 1.02 0.908 – 1.15 0.7 296 3179 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.04 0.926 – 1.18 0.484 296 3354 exclusion phecode
389.4 Tinnitus Sense Organs 1.04 0.926 – 1.16 0.531 336 3644 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 0.956 0.92 – 0.994 0.0228 2638 32790 exclusion phecode
394.2 Mitral valve disease Circulatory System 0.939 0.894 – 0.987 0.0125 1639 20116 exclusion phecode
394.3 Aortic valve disease Circulatory System 0.95 0.879 – 1.03 0.19 661 8535 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 0.955 0.878 – 1.04 0.288 555 7030 exclusion phecode
395 Heart valve disorders Circulatory System 0.948 0.909 – 0.988 0.0123 2254 28234 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.934 0.889 – 0.982 0.00712 1586 19409 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.927 0.781 – 1.1 0.384 132 1822 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.06 0.805 – 1.39 0.687 57 709 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.08 0.82 – 1.41 0.593 51 657 exclusion phecode
395.6 Heart valve replaced Circulatory System 0.955 0.888 – 1.03 0.216 743 9813 exclusion phecode
396 Abnormal heart sounds Circulatory System 0.979 0.905 – 1.06 0.588 700 7655 exclusion phecode
401 Hypertension Circulatory System 0.972 0.962 – 0.983 1.69e-07 43185 207901 exclusion phecode
401.1 Essential hypertension Circulatory System 0.972 0.962 – 0.982 1.56e-07 43131 207712 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 0.926 0.836 – 1.03 0.142 349 13252 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 0.944 0.809 – 1.1 0.47 157 2564 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.914 0.798 – 1.05 0.197 192 10832 exclusion phecode
401.3 Other hypertensive complications Circulatory System 0.793 0.565 – 1.11 0.179 29 1048 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 0.955 0.893 – 1.02 0.182 908 10889 exclusion phecode
411 Ischemic Heart Disease Circulatory System 0.989 0.974 – 1 0.178 17437 150784 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.979 0.943 – 1.02 0.282 2818 35061 exclusion phecode
411.2 Myocardial infarction Circulatory System 0.987 0.962 – 1.01 0.3 6320 76419 exclusion phecode
411.3 Angina pectoris Circulatory System 1.01 0.984 – 1.03 0.611 8723 98965 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 0.989 0.97 – 1.01 0.263 11218 107549 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.01 0.918 – 1.12 0.797 424 4851 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.989 0.966 – 1.01 0.334 7773 89870 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.99 0.918 – 1.07 0.799 695 8291 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 0.994 0.93 – 1.06 0.865 879 12319 exclusion phecode
414.2 ASCVD Circulatory System 0.809 0.596 – 1.1 0.172 38 477 exclusion phecode
415 Pulmonary heart disease Circulatory System 0.964 0.925 – 1 0.0779 2401 31183 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.2 0.88 – 1.64 0.248 44 513 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.934 0.826 – 1.06 0.273 266 4029 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 0.983 0.851 – 1.14 0.816 197 3027 exclusion phecode
416 Cardiomegaly Circulatory System 0.975 0.923 – 1.03 0.371 1300 17990 exclusion phecode
418 Nonspecific chest pain Circulatory System 0.977 0.963 – 0.992 0.00233 18523 198416 exclusion phecode
418.1 Precordial pain Circulatory System 0.969 0.929 – 1.01 0.147 2284 25880 exclusion phecode
420 Carditis Circulatory System 0.94 0.888 – 0.996 0.0346 1212 14499 exclusion phecode
420.1 Myocarditis Circulatory System 0.969 0.769 – 1.22 0.786 74 906 exclusion phecode
420.2 Pericarditis Circulatory System 0.905 0.843 – 0.971 0.00547 783 9266 exclusion phecode
420.21 Acute pericarditis Circulatory System 0.971 0.828 – 1.14 0.714 152 1553 exclusion phecode
420.22 Chronic pericarditis Circulatory System 0.899 0.704 – 1.15 0.393 62 736 exclusion phecode
420.3 Endocarditis Circulatory System 1 0.905 – 1.11 0.976 400 4851 exclusion phecode
425 Cardiomyopathy Circulatory System 0.951 0.877 – 1.03 0.226 608 8768 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.966 0.89 – 1.05 0.403 596 8515 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.939 0.741 – 1.19 0.602 68 931 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.97 0.783 – 1.2 0.782 89 1171 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 0.734 0.528 – 1.02 0.0646 28 403 exclusion phecode
426 Cardiac conduction disorders Circulatory System 1.02 0.985 – 1.05 0.299 3814 46144 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 1.04 0.978 – 1.1 0.215 1125 13826 exclusion phecode
426.21 First degree AV block Circulatory System 1.01 0.928 – 1.11 0.766 527 6397 exclusion phecode
426.23 Second degree AV block Circulatory System 1.06 0.937 – 1.21 0.341 268 2957 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1.03 0.913 – 1.15 0.663 289 3853 exclusion phecode
426.25 Other heart block Circulatory System 0.926 0.737 – 1.16 0.506 75 868 exclusion phecode
426.3 Bundle branch block Circulatory System 1 0.954 – 1.05 0.998 1850 22379 exclusion phecode
426.31 Right bundle branch block Circulatory System 1 0.935 – 1.08 0.931 840 10047 exclusion phecode
426.32 Left bundle branch block Circulatory System 1.01 0.942 – 1.07 0.859 947 11678 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 1.07 0.907 – 1.26 0.431 163 1747 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 0.842 0.618 – 1.15 0.274 38 404 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1.01 0.951 – 1.06 0.833 1258 16287 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 1.01 0.955 – 1.08 0.648 1155 14951 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 0.998 0.981 – 1.01 0.778 14168 146668 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.01 0.969 – 1.06 0.546 1998 22708 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.02 0.968 – 1.08 0.446 1538 16947 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.05 0.962 – 1.15 0.261 501 6314 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 0.988 0.966 – 1.01 0.297 7861 90141 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1.02 0.973 – 1.07 0.429 1921 22082 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.02 0.943 – 1.11 0.581 591 8043 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.03 0.888 – 1.19 0.729 190 2342 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.02 0.927 – 1.11 0.73 476 6663 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.963 0.884 – 1.05 0.378 554 6551 exclusion phecode
427.6 Premature beats Circulatory System 0.929 0.833 – 1.04 0.184 333 3786 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 1.11 0.878 – 1.41 0.377 73 831 exclusion phecode
427.7 Tachycardia NOS Circulatory System 0.994 0.94 – 1.05 0.829 1309 15806 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.926 0.818 – 1.05 0.229 247 2726 exclusion phecode
427.9 Palpitations Circulatory System 1 0.962 – 1.04 0.956 2672 28419 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 0.917 0.881 – 0.954 2.2e-05 2359 36584 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 0.927 0.862 – 0.997 0.0425 713 13567 exclusion phecode
428.2 Heart failure NOS Circulatory System 0.918 0.878 – 0.96 0.00019 1894 29081 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 0.944 0.859 – 1.04 0.225 462 5073 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.55 0.948 – 2.53 0.0806 19 447 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 1 0.896 – 1.12 0.971 336 3689 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 0.795 0.671 – 0.94 0.00742 126 1424 exclusion phecode
430 Intracranial hemorrhage Circulatory System 0.958 0.903 – 1.02 0.159 1172 13327 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 0.927 0.85 – 1.01 0.0874 569 6142 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1 0.909 – 1.1 0.978 439 5232 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 0.984 0.836 – 1.16 0.844 150 1749 exclusion phecode
433 Cerebrovascular disease Circulatory System 0.985 0.957 – 1.01 0.328 4755 58932 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 0.963 0.889 – 1.04 0.364 603 7600 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 0.898 0.755 – 1.07 0.223 123 1453 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.999 0.957 – 1.04 0.972 2213 28187 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 1.01 0.944 – 1.08 0.745 850 11261 exclusion phecode
433.3 Cerebral ischemia Circulatory System 0.97 0.922 – 1.02 0.243 1585 19448 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 0.972 0.917 – 1.03 0.341 1181 14450 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1 0.88 – 1.14 0.99 260 2923 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.958 0.886 – 1.04 0.286 632 8793 exclusion phecode
440 Atherosclerosis Circulatory System 1.03 0.947 – 1.12 0.514 602 8853 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 0.722 0.504 – 1.03 0.0753 23 734 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.02 0.923 – 1.14 0.651 365 5154 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.08 0.901 – 1.28 0.421 137 1851 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.03 0.92 – 1.16 0.594 315 4192 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.12 0.937 – 1.33 0.216 140 1944 exclusion phecode
442 Other aneurysm Circulatory System 0.934 0.874 – 0.998 0.0432 871 12071 exclusion phecode
442.1 Aortic aneurysm Circulatory System 0.953 0.88 – 1.03 0.234 611 9043 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.953 0.855 – 1.06 0.391 317 5469 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 0.651 0.479 – 0.884 0.00589 33 605 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.959 0.78 – 1.18 0.692 87 1106 exclusion phecode
442.4 Arterial dissection Circulatory System 0.685 0.513 – 0.914 0.0101 40 411 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 0.927 0.779 – 1.1 0.392 121 1440 exclusion phecode
443 Peripheral vascular disease Circulatory System 0.986 0.942 – 1.03 0.553 1934 26801 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 0.96 0.892 – 1.03 0.283 753 8551 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.892 0.744 – 1.07 0.213 111 2583 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 0.993 0.947 – 1.04 0.751 1857 25181 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.01 0.953 – 1.07 0.698 1122 16871 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 0.998 0.906 – 1.1 0.962 423 6204 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 0.95 0.837 – 1.08 0.43 236 3651 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.918 0.831 – 1.01 0.0892 395 5738 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 0.851 0.699 – 1.04 0.108 81 1295 exclusion phecode
446.5 Giant cell arteritis Circulatory System 0.897 0.781 – 1.03 0.121 206 2622 exclusion phecode
446.9 Arteritis NOS Circulatory System 0.935 0.772 – 1.13 0.49 106 1715 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.01 0.929 – 1.09 0.857 621 8868 exclusion phecode
447.1 Stricture of artery Circulatory System 0.976 0.883 – 1.08 0.631 397 5654 exclusion phecode
448 Disease of capillaries Circulatory System 1.01 0.818 – 1.25 0.906 86 1027 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.958 0.864 – 1.06 0.409 381 5156 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.964 0.924 – 1.01 0.0856 2252 27957 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.953 0.912 – 0.996 0.0307 2088 25960 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 0.996 0.886 – 1.12 0.942 305 4118 exclusion phecode
454 Varicose veins Circulatory System 0.984 0.962 – 1.01 0.16 8006 83774 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 0.984 0.962 – 1.01 0.159 8287 85950 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 1.08 0.962 – 1.21 0.198 338 4442 exclusion phecode
455 Hemorrhoids Circulatory System 0.99 0.975 – 1.01 0.233 16487 171594 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.928 0.75 – 1.15 0.492 85 1265 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.958 0.754 – 1.22 0.723 69 663 exclusion phecode
458 Hypotension Circulatory System 0.974 0.94 – 1.01 0.16 3122 40224 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.01 0.933 – 1.09 0.846 676 8957 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 0.887 0.739 – 1.07 0.2 118 1585 exclusion phecode
458.9 Hypotension NOS Circulatory System 0.976 0.932 – 1.02 0.306 1883 24554 exclusion phecode
459 Other disorders of circulatory system Circulatory System 0.978 0.958 – 1 0.0451 8927 112673 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.06 0.836 – 1.33 0.647 74 993 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 0.977 0.956 – 0.998 0.03 8849 111669 exclusion phecode
464 Acute sinusitis Respiratory 0.966 0.81 – 1.15 0.702 131 1476 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1 0.949 – 1.05 0.996 1510 16828 exclusion phecode
465.2 Acute pharyngitis Respiratory 0.936 0.858 – 1.02 0.131 553 6196 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.01 0.834 – 1.23 0.911 110 1204 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 0.962 0.929 – 0.996 0.0267 3440 34890 exclusion phecode
471 Nasal polyps Respiratory 0.967 0.928 – 1.01 0.111 2359 23487 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 0.968 0.897 – 1.05 0.41 694 7120 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 0.982 0.935 – 1.03 0.468 1688 18166 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.02 0.795 – 1.32 0.862 64 747 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.94 0.809 – 1.09 0.424 172 1889 exclusion phecode
473.4 Voice disturbance Respiratory 1 0.928 – 1.08 0.943 706 7600 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 0.965 0.913 – 1.02 0.201 1361 14138 exclusion phecode
474.1 Acute tonsillitis Respiratory 0.924 0.838 – 1.02 0.112 426 4455 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.994 0.927 – 1.07 0.86 868 8975 exclusion phecode
475 Chronic sinusitis Respiratory 0.985 0.939 – 1.03 0.538 1842 19122 exclusion phecode
476 Allergic rhinitis Respiratory 1.04 0.961 – 1.11 0.361 804 7930 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 0.989 0.939 – 1.04 0.69 1468 16711 exclusion phecode
478 Throat pain Respiratory 0.89 0.787 – 1.01 0.0604 269 2775 exclusion phecode
479 Other upper respiratory disease Respiratory 0.964 0.929 – 1 0.0612 2863 29922 exclusion phecode
480 Pneumonia Respiratory 0.975 0.949 – 1 0.067 5640 71497 exclusion phecode
480.1 Bacterial pneumonia Respiratory 0.965 0.934 – 0.998 0.0378 3627 46061 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 0.961 0.928 – 0.995 0.027 3210 40833 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 0.985 0.741 – 1.31 0.919 46 634 exclusion phecode
480.2 Viral pneumonia Respiratory 1.19 0.844 – 1.67 0.326 39 522 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 0.786 0.59 – 1.05 0.0998 42 678 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.04 0.945 – 1.15 0.391 423 5257 exclusion phecode
481 Influenza Respiratory 0.978 0.846 – 1.13 0.762 191 2422 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 0.924 0.764 – 1.12 0.413 116 1405 exclusion phecode
495 Asthma Respiratory 0.98 0.965 – 0.995 0.00948 17338 187928 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.04 0.886 – 1.22 0.62 164 1912 exclusion phecode
496 Chronic airway obstruction Respiratory 0.957 0.931 – 0.983 0.00147 5308 69214 exclusion phecode
496.1 Emphysema Respiratory 0.932 0.87 – 0.997 0.0417 851 11564 exclusion phecode
496.2 Chronic bronchitis Respiratory 0.943 0.892 – 0.995 0.0335 1317 19655 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 0.947 0.894 – 1 0.0637 1184 17996 exclusion phecode
496.3 Bronchiectasis Respiratory 1.01 0.949 – 1.07 0.797 1112 13006 exclusion phecode
497 Bronchitis Respiratory 1.02 0.911 – 1.14 0.748 345 4518 exclusion phecode
500 Lung disease due to external agents Respiratory 0.974 0.846 – 1.12 0.719 190 2563 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.04 0.749 – 1.46 0.799 37 557 exclusion phecode
500.2 Pneumoconiosis Respiratory 1.01 0.838 – 1.23 0.882 105 1418 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 0.981 0.876 – 1.1 0.739 319 4401 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.905 0.823 – 0.996 0.0407 411 6032 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 1.16 0.998 – 1.35 0.0535 188 3519 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.781 0.667 – 0.915 0.00223 142 2260 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 0.902 0.645 – 1.26 0.549 34 435 exclusion phecode
506 Empyema and pneumothorax Respiratory 0.928 0.858 – 1 0.0568 651 8026 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1 0.968 – 1.04 0.952 3569 43880 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.981 0.924 – 1.04 0.542 1123 13891 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.96 0.906 – 1.02 0.165 1185 17527 exclusion phecode
509.1 Respiratory failure Respiratory 0.927 0.869 – 0.989 0.0211 923 13859 exclusion phecode
509.2 Respiratory insufficiency Respiratory 0.913 0.853 – 0.978 0.00981 807 12198 exclusion phecode
509.5 Respiratory arrest Respiratory 0.93 0.743 – 1.16 0.527 74 1008 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.11 0.951 – 1.29 0.188 184 2579 exclusion phecode
510 Other diseases of lung Respiratory 0.868 0.79 – 0.954 0.00341 432 5174 exclusion phecode
512 Other symptoms of respiratory system Respiratory 0.943 0.917 – 0.969 2.8e-05 5300 64335 exclusion phecode
512.1 Wheezing Respiratory 0.956 0.798 – 1.14 0.622 126 1550 exclusion phecode
512.2 Painful respiration Respiratory 0.851 0.72 – 1.01 0.0592 140 1523 exclusion phecode
512.7 Shortness of breath Respiratory 0.949 0.916 – 0.982 0.003 3323 41531 exclusion phecode
512.8 Cough Respiratory 0.93 0.887 – 0.976 0.00343 1711 20522 exclusion phecode
512.9 Other dyspnea Respiratory 0.945 0.866 – 1.03 0.203 532 6453 exclusion phecode
513 Respiratory abnormalities Respiratory 1.01 0.901 – 1.13 0.901 344 4276 exclusion phecode
513.3 Hypoventilation Respiratory 0.925 0.646 – 1.32 0.671 31 572 exclusion phecode
513.4 Hyperventilation Respiratory 1.07 0.912 – 1.26 0.394 173 2037 exclusion phecode
513.8 Disorders of diaphragm Respiratory 0.942 0.767 – 1.16 0.57 94 1002 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 0.912 0.864 – 0.962 0.000742 1360 16815 exclusion phecode
516 Abnormal sputum Respiratory 0.953 0.9 – 1.01 0.103 1221 14739 exclusion phecode
516.1 Hemoptysis Respiratory 0.951 0.897 – 1.01 0.0892 1196 14347 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.981 0.954 – 1.01 0.171 5349 66112 exclusion phecode
519.2 Respiratory complications Respiratory 0.967 0.823 – 1.14 0.687 149 2197 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.984 0.957 – 1.01 0.269 5049 62577 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.979 0.854 – 1.12 0.76 216 2189 exclusion phecode
520 Disorders of tooth development Digestive 0.975 0.927 – 1.03 0.337 1587 16220 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.892 0.636 – 1.25 0.506 33 402 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 1.01 0.96 – 1.06 0.791 1872 18920 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 0.97 0.926 – 1.01 0.183 1978 22781 exclusion phecode
521.1 Dental caries Digestive 0.973 0.93 – 1.02 0.242 1980 22849 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 0.97 0.917 – 1.03 0.299 1276 13546 exclusion phecode
522.5 Periapical abscess Digestive 0.966 0.901 – 1.04 0.332 834 8939 exclusion phecode
523 Gingival and periodontal diseases Digestive 0.96 0.906 – 1.02 0.177 1208 12891 exclusion phecode
523.1 Gingivitis Digestive 1.02 0.811 – 1.28 0.873 73 795 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 0.95 0.887 – 1.02 0.151 859 9141 exclusion phecode
523.31 Acute periodontitis Digestive 0.978 0.892 – 1.07 0.632 499 5333 exclusion phecode
523.32 Chronic periodontitis Digestive 0.927 0.838 – 1.02 0.135 405 4296 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.927 0.817 – 1.05 0.241 250 2629 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.966 0.846 – 1.1 0.614 230 2442 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 1.03 0.978 – 1.08 0.28 1776 19685 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.83 0.642 – 1.07 0.154 55 521 exclusion phecode
526 Diseases of the jaws Digestive 0.966 0.892 – 1.05 0.402 657 7001 exclusion phecode
526.1 Cysts of the jaws Digestive 1.07 0.931 – 1.22 0.354 234 2404 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.878 0.671 – 1.15 0.341 49 473 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 0.888 0.762 – 1.03 0.126 168 1904 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.882 0.756 – 1.03 0.11 164 1846 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.955 0.753 – 1.21 0.706 75 816 exclusion phecode
526.9 Jaw disease NOS Digestive 1 0.848 – 1.18 0.985 158 1726 exclusion phecode
527 Diseases of the salivary glands Digestive 0.997 0.905 – 1.1 0.947 455 5107 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 0.867 0.67 – 1.12 0.276 54 601 exclusion phecode
527.2 Sialoadenitis Digestive 1.04 0.909 – 1.18 0.589 240 2739 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.09 0.788 – 1.52 0.592 42 460 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 1.1 0.883 – 1.38 0.383 84 875 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.995 0.956 – 1.04 0.808 2634 28527 exclusion phecode
528.1 Stomatitis and mucositis Digestive 0.898 0.802 – 1.01 0.0646 301 3440 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 0.907 0.8 – 1.03 0.131 248 2842 exclusion phecode
528.12 Oral aphthae Digestive 0.816 0.633 – 1.05 0.117 56 628 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.995 0.823 – 1.2 0.958 114 1341 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.992 0.794 – 1.24 0.942 90 909 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.956 0.735 – 1.24 0.736 65 703 exclusion phecode
528.5 Diseases of lips Digestive 0.978 0.891 – 1.07 0.635 474 5001 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 1.18 1.01 – 1.37 0.0324 194 2174 exclusion phecode
528.7 Sialolithiasis Digestive 1.06 0.923 – 1.22 0.41 219 2313 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 0.976 0.91 – 1.05 0.507 829 9018 exclusion phecode
529.1 Glossitis Digestive 0.848 0.734 – 0.98 0.026 186 2166 exclusion phecode
530 Diseases of esophagus Digestive 0.983 0.969 – 0.997 0.0156 21728 206908 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.981 0.967 – 0.995 0.00693 20403 201209 exclusion phecode
530.11 GERD Digestive 0.981 0.964 – 0.997 0.0208 14956 164974 exclusion phecode
530.12 Ulcer of esophagus Digestive 0.952 0.919 – 0.987 0.0073 3155 35906 exclusion phecode
530.14 Reflux esophagitis Digestive 0.97 0.947 – 0.994 0.0149 6827 75648 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.02 0.953 – 1.09 0.592 943 11936 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 0.966 0.911 – 1.02 0.255 1178 12933 exclusion phecode
530.5 Disorders of esophageal motility Digestive 0.998 0.902 – 1.1 0.97 399 4577 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.94 0.772 – 1.15 0.541 101 1024 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 1.03 0.893 – 1.18 0.723 215 2522 exclusion phecode
530.9 Heartburn Digestive 1.01 0.959 – 1.07 0.67 1495 15580 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1 0.973 – 1.04 0.814 4226 49668 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.973 0.874 – 1.08 0.61 352 4319 exclusion phecode
531.2 Gastric ulcer Digestive 1.01 0.973 – 1.06 0.508 2423 28820 exclusion phecode
531.3 Duodenal ulcer Digestive 0.996 0.95 – 1.04 0.868 1799 20881 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 1.04 0.908 – 1.18 0.604 239 2939 exclusion phecode
532 Dysphagia Digestive 0.993 0.963 – 1.02 0.673 4228 46637 exclusion phecode
535 Gastritis and duodenitis Digestive 0.995 0.98 – 1.01 0.535 18173 191285 exclusion phecode
535.1 Acute gastritis Digestive 0.996 0.924 – 1.07 0.924 717 8385 exclusion phecode
535.2 Atrophic gastritis Digestive 1.02 0.895 – 1.17 0.743 234 2533 exclusion phecode
535.6 Duodenitis Digestive 0.997 0.968 – 1.03 0.837 4682 54128 exclusion phecode
535.8 Other specified gastritis Digestive 0.995 0.967 – 1.02 0.714 5239 57860 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.932 0.75 – 1.16 0.529 83 858 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.955 0.824 – 1.11 0.542 175 1868 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 0.966 0.923 – 1.01 0.122 2045 24138 exclusion phecode
540 Appendiceal conditions Digestive 1.04 0.992 – 1.08 0.107 2266 23459 exclusion phecode
540.1 Appendicitis Digestive 1.04 0.996 – 1.09 0.0712 2134 21972 exclusion phecode
540.11 Acute appendicitis Digestive 1.04 0.996 – 1.09 0.0715 1944 19778 exclusion phecode
550 Abdominal hernia Digestive 0.989 0.977 – 1 0.0833 29510 211276 exclusion phecode
550.1 Inguinal hernia Digestive 1.01 0.986 – 1.03 0.571 10584 84628 exclusion phecode
550.2 Diaphragmatic hernia Digestive 0.98 0.965 – 0.995 0.0111 16946 174899 exclusion phecode
550.3 Femoral hernia Digestive 1.06 0.965 – 1.16 0.229 492 4835 exclusion phecode
550.4 Umbilical hernia Digestive 0.947 0.908 – 0.989 0.0129 2206 26237 exclusion phecode
550.5 Ventral hernia Digestive 0.987 0.944 – 1.03 0.557 2061 24752 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 0.994 0.957 – 1.03 0.756 2931 33097 exclusion phecode
555.1 Regional enteritis Digestive 0.995 0.936 – 1.06 0.87 1107 13156 exclusion phecode
555.2 Ulcerative colitis Digestive 1 0.956 – 1.05 0.987 2119 23491 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.01 0.909 – 1.12 0.842 381 4097 exclusion phecode
556 Ulceration of the lower GI tract Digestive 0.915 0.849 – 0.986 0.0201 693 7778 exclusion phecode
556.1 Ulceration of intestine Digestive 0.953 0.866 – 1.05 0.324 429 4916 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.972 0.839 – 1.13 0.708 198 2289 exclusion phecode
557.1 Celiac disease Digestive 1.05 0.994 – 1.12 0.079 1289 13848 exclusion phecode
558 Noninfectious gastroenteritis Digestive 0.974 0.955 – 0.994 0.0119 10139 116051 exclusion phecode
559 Ileostomy status Digestive 1.03 0.961 – 1.1 0.439 998 11716 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 0.98 0.941 – 1.02 0.318 2534 28294 exclusion phecode
560.1 Paralytic ileus Digestive 0.976 0.872 – 1.09 0.667 318 3637 exclusion phecode
560.2 Impaction of intestine Digestive 0.887 0.763 – 1.03 0.117 165 1951 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.04 0.95 – 1.14 0.403 547 6023 exclusion phecode
560.4 Other intestinal obstruction Digestive 0.994 0.951 – 1.04 0.781 2181 24215 exclusion phecode
561 Symptoms involving digestive system Digestive 0.996 0.977 – 1.02 0.678 11071 118093 exclusion phecode
561.1 Diarrhea Digestive 1.02 0.906 – 1.15 0.746 307 3348 exclusion phecode
561.2 Flatulence Digestive 0.986 0.929 – 1.05 0.631 1188 12682 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 0.989 0.973 – 1 0.163 17018 154122 exclusion phecode
562.1 Diverticulosis Digestive 0.989 0.974 – 1 0.174 16988 154070 exclusion phecode
563 Constipation Digestive 0.99 0.965 – 1.01 0.412 6720 75745 exclusion phecode
564 Functional digestive disorders Digestive 0.989 0.972 – 1.01 0.209 14222 154657 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 0.976 0.945 – 1.01 0.141 4007 42741 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 0.998 0.936 – 1.06 0.959 1036 11923 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 0.992 0.972 – 1.01 0.437 9638 108537 exclusion phecode
565 Anal and rectal conditions Digestive 1 0.98 – 1.02 0.999 10014 106323 exclusion phecode
565.1 Anal and rectal polyp Digestive 1.01 0.977 – 1.04 0.694 4897 51529 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 0.973 0.891 – 1.06 0.54 519 6610 exclusion phecode
568 Other disorders of peritoneum Digestive 0.978 0.936 – 1.02 0.311 2143 24137 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 0.977 0.934 – 1.02 0.305 2045 22970 exclusion phecode
569 Other disorders of intestine Digestive 0.969 0.932 – 1.01 0.111 2686 29901 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.956 0.776 – 1.18 0.674 94 1003 exclusion phecode
569.2 Gastrointestinal complications Digestive 0.928 0.83 – 1.04 0.185 318 3425 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 0.925 0.879 – 0.974 0.00279 1504 21458 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 0.922 0.865 – 0.983 0.0136 944 12403 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.975 0.754 – 1.26 0.848 55 810 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 0.813 0.675 – 0.979 0.0293 105 1910 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.953 0.866 – 1.05 0.324 430 6942 exclusion phecode
571.81 Portal hypertension Digestive 0.902 0.79 – 1.03 0.129 214 3717 exclusion phecode
572 Ascites (non malignant) Digestive 0.958 0.895 – 1.03 0.214 870 11009 exclusion phecode
573 Other disorders of liver Digestive 0.948 0.885 – 1.02 0.132 842 10720 exclusion phecode
573.2 Liver replaced by transplant Digestive 1.23 0.731 – 2.07 0.435 15 719 exclusion phecode
573.3 Hepatomegaly Digestive 0.933 0.794 – 1.1 0.404 145 2103 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 0.996 0.91 – 1.09 0.923 498 6264 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 0.953 0.912 – 0.997 0.0345 2045 24822 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 0.969 0.812 – 1.16 0.727 118 1416 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 0.977 0.957 – 0.997 0.0241 9995 116039 exclusion phecode
574.1 Cholelithiasis Digestive 0.983 0.962 – 1.01 0.136 8674 100916 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 1.03 0.964 – 1.11 0.358 915 10927 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.961 0.929 – 0.994 0.0217 3535 40608 exclusion phecode
574.2 Calculus of bile duct Digestive 0.95 0.903 – 1 0.0481 1591 19218 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.972 0.925 – 1.02 0.255 1684 20184 exclusion phecode
575 Other biliary tract disease Digestive 0.968 0.929 – 1.01 0.12 2417 28197 exclusion phecode
575.1 Cholangitis Digestive 1.05 0.925 – 1.2 0.442 246 3359 exclusion phecode
575.2 Obstruction of bile duct Digestive 1.01 0.917 – 1.11 0.868 469 5513 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.998 0.891 – 1.12 0.97 329 3555 exclusion phecode
575.7 Other disorders of gallbladder Digestive 0.955 0.893 – 1.02 0.183 903 10419 exclusion phecode
575.8 Other disorders of biliary tract Digestive 0.93 0.858 – 1.01 0.0742 629 7533 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 0.926 0.807 – 1.06 0.279 201 2448 exclusion phecode
577 Diseases of pancreas Digestive 0.939 0.892 – 0.987 0.0144 1539 18975 exclusion phecode
577.1 Acute pancreatitis Digestive 0.942 0.888 – 0.998 0.0436 1156 14294 exclusion phecode
577.2 Chronic pancreatitis Digestive 1 0.89 – 1.13 0.985 289 3652 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.99 0.861 – 1.14 0.887 214 2618 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 0.99 0.973 – 1.01 0.275 14019 150844 exclusion phecode
578.1 Hematemesis Digestive 1.02 0.96 – 1.08 0.521 1103 13997 exclusion phecode
578.2 Blood in stool Digestive 1.02 0.965 – 1.07 0.545 1574 18437 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 0.988 0.967 – 1.01 0.27 9164 96331 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.998 0.964 – 1.03 0.897 3559 38564 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.966 0.904 – 1.03 0.308 915 11399 exclusion phecode
579.2 Splenomegaly Digestive 0.848 0.733 – 0.98 0.0258 164 2991 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.96 0.903 – 1.02 0.198 1127 11968 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.891 0.8 – 0.992 0.0359 320 10528 exclusion phecode
580.1 Glomerulonephritis Genitourinary 0.868 0.755 – 0.997 0.0449 189 7088 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.875 0.579 – 1.32 0.527 18 560 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.1 0.801 – 1.52 0.552 37 957 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.826 0.704 – 0.968 0.0182 140 5813 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 0.929 0.777 – 1.11 0.418 113 3276 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.957 0.755 – 1.21 0.713 66 1741 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.965 0.764 – 1.22 0.766 67 1798 exclusion phecode
585 Renal failure Genitourinary 0.925 0.888 – 0.964 0.000222 2224 47440 exclusion phecode
585.1 Acute renal failure Genitourinary 0.934 0.89 – 0.98 0.00584 1647 30586 exclusion phecode
585.2 Renal failure NOS Genitourinary 0.931 0.847 – 1.02 0.144 407 10013 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 0.917 0.837 – 1 0.0628 445 17878 exclusion phecode
585.31 Renal dialysis Genitourinary 0.821 0.658 – 1.02 0.0794 67 3525 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 0.963 0.917 – 1.01 0.142 1613 23513 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.976 0.739 – 1.29 0.864 46 1460 exclusion phecode
586.11 Small kidney Genitourinary 0.908 0.672 – 1.23 0.53 38 1242 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 0.962 0.89 – 1.04 0.324 653 8642 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.966 0.662 – 1.41 0.859 26 569 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.961 0.876 – 1.05 0.405 473 6532 exclusion phecode
587 Kidney replaced by transpant Genitourinary 0.854 0.597 – 1.22 0.386 24 2697 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 0.873 0.581 – 1.31 0.514 21 735 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.17 0.859 – 1.59 0.321 42 808 exclusion phecode
590 Pyelonephritis Genitourinary 0.972 0.904 – 1.04 0.44 801 10146 exclusion phecode
591 Urinary tract infection Genitourinary 1 0.976 – 1.02 0.975 7516 88690 exclusion phecode
592 Cystitis and urethritis Genitourinary 0.983 0.938 – 1.03 0.453 1928 21171 exclusion phecode
592.1 Cystitis Genitourinary 0.987 0.942 – 1.03 0.597 1886 20769 exclusion phecode
592.11 Acute cystitis Genitourinary 1.01 0.812 – 1.25 0.947 86 944 exclusion phecode
592.12 Chronic cystitis Genitourinary 1 0.92 – 1.09 0.964 577 6386 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.03 0.88 – 1.2 0.719 173 1820 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 0.911 0.765 – 1.08 0.295 121 1186 exclusion phecode
593 Hematuria Genitourinary 1.01 0.992 – 1.03 0.227 10355 112993 exclusion phecode
594 Urinary calculus Genitourinary 1.01 0.975 – 1.04 0.655 3976 45158 exclusion phecode
594.1 Calculus of kidney Genitourinary 0.983 0.939 – 1.03 0.455 1936 22297 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.11 1 – 1.22 0.0422 430 5060 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.01 0.962 – 1.07 0.59 1479 17012 exclusion phecode
594.8 Renal colic Genitourinary 0.994 0.941 – 1.05 0.846 1333 14789 exclusion phecode
595 Hydronephrosis Genitourinary 0.998 0.938 – 1.06 0.961 1061 13692 exclusion phecode
596 Other disorders of bladder Genitourinary 0.988 0.963 – 1.01 0.379 6147 66514 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 1.04 0.98 – 1.1 0.199 1187 12461 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 0.981 0.923 – 1.04 0.546 1093 12035 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 0.978 0.939 – 1.02 0.269 2569 27514 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 0.981 0.939 – 1.03 0.394 2151 23144 exclusion phecode
597.2 Urinary complications NEC Genitourinary 0.899 0.663 – 1.22 0.494 38 544 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 0.981 0.94 – 1.02 0.377 2262 24317 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.02 0.871 – 1.2 0.788 158 2095 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.997 0.979 – 1.02 0.787 12379 133880 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.998 0.798 – 1.25 0.985 79 1139 exclusion phecode
599.2 Retention of urine Genitourinary 0.976 0.945 – 1.01 0.14 3915 44012 exclusion phecode
599.3 Dysuria Genitourinary 0.982 0.912 – 1.06 0.629 767 8611 exclusion phecode
599.4 Urinary incontinence Genitourinary 1 0.976 – 1.03 0.879 6225 66676 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 0.982 0.944 – 1.02 0.363 2659 28363 exclusion phecode
599.6 Oliguria and anuria Genitourinary 0.842 0.629 – 1.13 0.249 37 695 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.1 0.787 – 1.54 0.57 37 432 exclusion phecode
599.9 Other abnormality of urination Genitourinary 0.96 0.907 – 1.02 0.163 1246 13115 exclusion phecode
600 Hyperplasia of prostate Genitourinary 0.989 0.965 – 1.01 0.407 6386 55946 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 0.959 0.907 – 1.01 0.146 1239 13404 exclusion phecode
601.1 Prostatitis Genitourinary 0.931 0.873 – 0.993 0.0292 935 9926 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.988 0.836 – 1.17 0.889 135 1527 exclusion phecode
601.12 Chronic prostatitis Genitourinary 0.953 0.875 – 1.04 0.261 548 5689 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 0.889 0.66 – 1.2 0.44 45 421 exclusion phecode
601.4 Balanoposthitis Genitourinary 0.981 0.846 – 1.14 0.795 179 1907 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.984 0.841 – 1.15 0.836 168 2013 exclusion phecode
602 Other disorders of prostate Genitourinary 0.941 0.878 – 1.01 0.0919 787 8223 exclusion phecode
603 Other disorders of testis Genitourinary 1.05 0.99 – 1.11 0.108 1349 14624 exclusion phecode
603.1 Hydrocele Genitourinary 1.08 1.01 – 1.16 0.0356 832 8911 exclusion phecode
604 Disorders of penis Genitourinary 0.994 0.95 – 1.04 0.778 2065 22593 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.03 0.976 – 1.08 0.31 1692 18724 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 0.962 0.826 – 1.12 0.616 168 1816 exclusion phecode
608 Other disorders of male genital organs Genitourinary 0.983 0.938 – 1.03 0.488 1823 19075 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.05 0.883 – 1.25 0.579 135 1361 exclusion phecode
609.1 Infertility, male Genitourinary 0.96 0.717 – 1.28 0.783 49 503 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 1.07 0.875 – 1.31 0.51 99 1002 exclusion phecode
610 Benign mammary dysplasias Genitourinary 1 0.958 – 1.05 0.889 1972 19921 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.995 0.922 – 1.07 0.905 722 7285 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 0.905 0.794 – 1.03 0.137 238 2420 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 1.07 0.928 – 1.22 0.366 235 2364 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 1.02 0.956 – 1.08 0.591 1121 11242 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1 0.914 – 1.1 0.979 522 5394 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.957 0.903 – 1.01 0.139 1239 12358 exclusion phecode
611.1 Abnormal mammogram Genitourinary 0.853 0.633 – 1.15 0.298 48 428 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.957 0.902 – 1.01 0.14 1195 11952 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.983 0.908 – 1.06 0.674 675 7059 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.992 0.915 – 1.08 0.848 644 6692 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 0.851 0.66 – 1.1 0.212 62 597 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 1.05 0.99 – 1.12 0.099 1213 13058 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 1.1 1 – 1.21 0.0474 519 5681 exclusion phecode
613.5 Mastodynia Genitourinary 1.37 1 – 1.86 0.0467 52 617 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 0.976 0.893 – 1.07 0.589 543 5480 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1.01 0.883 – 1.15 0.913 252 2598 exclusion phecode
613.9 Breast disorder NOS Genitourinary – 154 1613 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 1.02 0.99 – 1.05 0.183 4555 46930 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 1.03 0.982 – 1.08 0.229 2029 21054 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1 0.926 – 1.09 0.936 674 6917 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.875 0.648 – 1.18 0.383 50 511 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.998 0.893 – 1.12 0.975 335 3472 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.972 0.859 – 1.1 0.649 284 2951 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1 0.874 – 1.15 0.966 219 2266 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 1.02 0.978 – 1.07 0.32 2070 21159 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.02 0.956 – 1.09 0.565 1039 10678 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.96 0.858 – 1.07 0.473 334 3428 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 1.1 1.01 – 1.2 0.0268 632 6251 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.94 0.819 – 1.08 0.382 205 2238 exclusion phecode
615 Endometriosis Genitourinary 1.01 0.979 – 1.05 0.427 3310 33907 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 0.864 0.756 – 0.987 0.0308 222 2413 exclusion phecode
618 Genital prolapse Genitourinary 0.985 0.964 – 1.01 0.184 8798 89103 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 0.985 0.958 – 1.01 0.289 5502 56218 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 0.989 0.958 – 1.02 0.503 4144 40977 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 0.975 0.877 – 1.08 0.636 373 3802 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.994 0.904 – 1.09 0.909 475 5087 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 0.99 0.966 – 1.01 0.425 6911 70025 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.971 0.892 – 1.06 0.493 582 5971 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 1.01 0.965 – 1.05 0.806 2576 26151 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.97 0.93 – 1.01 0.164 2316 23245 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 0.963 0.911 – 1.02 0.183 1403 14196 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 1.03 0.962 – 1.09 0.439 1065 10872 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 0.823 0.631 – 1.07 0.15 51 574 exclusion phecode
621 Endometrial hyperplasia Genitourinary 1.03 0.961 – 1.11 0.384 819 8975 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.999 0.976 – 1.02 0.905 8117 82727 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 1 0.977 – 1.03 0.799 5988 62113 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 1 0.966 – 1.05 0.807 2767 26862 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 0.983 0.922 – 1.05 0.6 1009 10437 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 1.03 0.944 – 1.12 0.529 582 6032 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 1.04 0.892 – 1.22 0.593 171 1815 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 1.01 0.897 – 1.13 0.894 320 3333 exclusion phecode
624.9 stress incontinence, female Genitourinary 1 0.97 – 1.03 0.949 4407 45979 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.994 0.953 – 1.04 0.795 2427 24139 exclusion phecode
625.1 Dyspareunia Genitourinary 0.987 0.923 – 1.05 0.695 990 9975 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.995 0.976 – 1.01 0.564 13511 95319 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.989 0.97 – 1.01 0.277 11804 91590 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 1.01 0.81 – 1.27 0.901 86 937 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 0.983 0.961 – 1.01 0.154 8024 77074 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 1.02 0.969 – 1.08 0.446 1612 16218 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.987 0.951 – 1.02 0.478 3186 32196 exclusion phecode
626.2 Dysmenorrhea Genitourinary 1.03 0.971 – 1.08 0.365 1464 15245 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 0.881 0.735 – 1.06 0.172 119 1378 exclusion phecode
626.8 Infertility, female Genitourinary 1.02 0.959 – 1.08 0.543 1228 12044 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.98 0.958 – 1 0.1 7565 79145 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 0.988 0.963 – 1.01 0.358 6532 68560 exclusion phecode
627.2 Symptomatic menopause Genitourinary 0.855 0.725 – 1.01 0.061 136 1443 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.985 0.916 – 1.06 0.675 797 8226 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 0.901 0.79 – 1.03 0.119 241 2526 exclusion phecode
628 Ovarian cyst Genitourinary 1.02 0.984 – 1.05 0.308 3823 39143 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.02 0.99 – 1.05 0.18 4734 32491 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.977 0.915 – 1.04 0.487 1022 10166 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.04 0.919 – 1.17 0.555 301 2930 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.993 0.945 – 1.04 0.786 1817 15648 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.999 0.926 – 1.08 0.974 798 7773 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.989 0.93 – 1.05 0.716 1167 11078 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 0.985 0.941 – 1.03 0.522 2145 17938 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.991 0.908 – 1.08 0.845 563 5515 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 0.999 0.934 – 1.07 0.968 985 9563 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 1.06 0.806 – 1.4 0.665 61 625 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.04 0.968 – 1.11 0.31 981 10029 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 0.952 0.84 – 1.08 0.437 271 2751 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 1.21 1.03 – 1.43 0.0193 185 1948 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.12 0.933 – 1.35 0.22 131 1363 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.988 0.929 – 1.05 0.704 1147 11281 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 1.01 0.96 – 1.06 0.779 2016 18854 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.01 0.78 – 1.3 0.965 59 600 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 0.891 0.786 – 1.01 0.071 258 2476 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.04 0.845 – 1.27 0.732 103 1010 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.03 0.873 – 1.21 0.732 176 1744 exclusion phecode
650 Normal delivery Pregnancy Complications 0.993 0.944 – 1.04 0.789 1772 17119 exclusion phecode
651 Multiple gestation Pregnancy Complications 1.07 0.947 – 1.21 0.273 310 3126 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 1.04 0.984 – 1.1 0.167 1590 14954 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.998 0.941 – 1.06 0.95 1281 12312 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 0.725 0.566 – 0.929 0.0109 66 656 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 1.03 0.997 – 1.07 0.0705 3940 26537 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 0.94 0.763 – 1.16 0.562 95 977 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 1.05 1 – 1.11 0.0315 2086 16594 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 1.05 0.956 – 1.16 0.29 492 4803 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 1.02 0.991 – 1.06 0.157 4864 26481 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.01 0.967 – 1.06 0.628 2333 19087 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.11 0.923 – 1.34 0.26 146 1472 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.01 0.884 – 1.16 0.872 241 2368 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.99 0.747 – 1.31 0.944 58 565 exclusion phecode
679 Complications of in utero procedures Dermatologic 0.817 0.606 – 1.1 0.184 48 490 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 0.967 0.937 – 0.998 0.036 4027 51507 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 1.06 0.95 – 1.18 0.294 353 4109 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 0.976 0.876 – 1.09 0.657 346 3838 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.97 0.934 – 1.01 0.103 2928 38974 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.968 0.932 – 1 0.0808 2932 39017 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.968 0.933 – 1.01 0.0899 2904 38675 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 0.841 0.76 – 0.931 0.000859 358 4375 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 0.875 0.817 – 0.938 0.000147 807 9636 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 0.967 0.917 – 1.02 0.221 1475 17138 exclusion phecode
686.3 Pilonidal cyst Dermatologic 0.996 0.9 – 1.1 0.933 404 4550 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.11 0.971 – 1.27 0.127 255 2627 exclusion phecode
687 Symptoms affecting skin Dermatologic 0.879 0.791 – 0.978 0.0175 351 3979 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.98 0.927 – 1.04 0.483 1288 15623 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 0.86 0.746 – 0.991 0.0368 195 2039 exclusion phecode
687.3 Changes in skin texture Dermatologic 0.886 0.698 – 1.12 0.317 71 794 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 0.976 0.932 – 1.02 0.31 1962 21730 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1.02 0.985 – 1.05 0.301 3950 41432 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 1.12 0.829 – 1.51 0.466 46 529 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 1.27 0.88 – 1.83 0.203 36 386 exclusion phecode
691 Congenital anomalies of skin Dermatologic 1.39 1.08 – 1.79 0.0116 80 876 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 1.07 0.989 – 1.16 0.0942 723 7202 exclusion phecode
694.1 Vitiligo Dermatologic 1.13 0.794 – 1.61 0.498 39 445 exclusion phecode
694.2 Other dyschromia Dermatologic 1.1 1.01 – 1.2 0.0377 597 5704 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 0.898 0.707 – 1.14 0.377 68 847 exclusion phecode
695 Erythematous conditions Dermatologic 1.01 0.959 – 1.07 0.667 1513 17392 exclusion phecode
695.1 Toxic erythema Dermatologic 0.843 0.665 – 1.07 0.158 66 829 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.06 0.85 – 1.32 0.603 87 966 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 1.01 0.727 – 1.4 0.951 36 395 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.02 0.758 – 1.37 0.899 48 516 exclusion phecode
695.3 Rosacea Dermatologic 0.947 0.827 – 1.09 0.435 224 2212 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 0.998 0.868 – 1.15 0.98 219 3148 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.1 0.861 – 1.41 0.44 71 955 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.01 0.869 – 1.18 0.862 179 2643 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 1.02 0.933 – 1.12 0.65 527 5652 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1.08 0.908 – 1.27 0.402 146 1752 exclusion phecode
695.81 Erythema nodosum Dermatologic 1.37 1.01 – 1.85 0.0415 55 604 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.02 0.899 – 1.15 0.788 280 3288 exclusion phecode
696 Psoriasis and related disorders Dermatologic 1.01 0.958 – 1.07 0.64 1320 16391 exclusion phecode
696.4 Psoriasis Dermatologic 1.01 0.953 – 1.07 0.767 1285 16044 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 1.01 0.946 – 1.08 0.761 954 12132 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.972 0.883 – 1.07 0.566 450 5291 exclusion phecode
697 Sarcoidosis Dermatologic 0.895 0.794 – 1.01 0.0691 268 4024 exclusion phecode
698 Pruritus and related conditions Dermatologic 0.969 0.889 – 1.06 0.475 550 5719 exclusion phecode
700 Corns and callosities Dermatologic 1.03 0.887 – 1.2 0.682 185 2154 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.981 0.946 – 1.02 0.28 3312 34327 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 1.1 0.828 – 1.45 0.517 54 590 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 0.968 0.921 – 1.02 0.197 1716 17453 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 0.819 0.597 – 1.12 0.215 38 428 exclusion phecode
701.4 Keloid scar Dermatologic 0.985 0.839 – 1.16 0.856 162 1675 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 0.929 0.832 – 1.04 0.189 338 3396 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.1 0.851 – 1.42 0.474 64 767 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.01 0.979 – 1.05 0.48 3821 38063 exclusion phecode
702.1 Actinic keratosis Dermatologic 1.02 0.966 – 1.07 0.55 1753 17669 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 1.01 0.971 – 1.06 0.513 2208 21594 exclusion phecode
703 Diseases of nail, NOS Dermatologic 0.956 0.835 – 1.09 0.515 230 2525 exclusion phecode
703.1 Ingrowing nail Dermatologic 0.892 0.824 – 0.966 0.00476 620 7152 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 0.949 0.918 – 0.98 0.00162 3837 39206 exclusion phecode
704.1 Alopecia Dermatologic 1.06 0.846 – 1.33 0.606 83 992 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 0.921 0.719 – 1.18 0.518 58 561 exclusion phecode
705 Disorders of sweat glands Dermatologic 0.954 0.805 – 1.13 0.59 139 1822 exclusion phecode
705.3 Hidradenitis Dermatologic 1 0.832 – 1.21 0.972 114 1494 exclusion phecode
705.8 Hyperhidrosis Dermatologic 0.85 0.767 – 0.942 0.00187 361 4228 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 0.956 0.931 – 0.981 0.000717 6063 61421 exclusion phecode
706.1 Acne Dermatologic 0.673 0.52 – 0.872 0.00272 57 622 exclusion phecode
706.2 Sebaceous cyst Dermatologic 0.967 0.943 – 0.992 0.0103 6421 64821 exclusion phecode
707 Chronic ulcer of skin Dermatologic 0.948 0.885 – 1.02 0.125 823 13259 exclusion phecode
707.1 Decubitus ulcer Dermatologic 0.993 0.902 – 1.09 0.888 426 6025 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 0.977 0.936 – 1.02 0.296 2182 24985 exclusion phecode
709.2 Sicca syndrome Dermatologic 0.915 0.81 – 1.03 0.151 260 3817 exclusion phecode
709.3 Systemic sclerosis Dermatologic 0.949 0.772 – 1.17 0.622 90 1293 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.802 0.582 – 1.1 0.176 32 505 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.998 0.951 – 1.05 0.92 1812 19648 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.906 0.808 – 1.02 0.089 290 4237 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 0.918 0.814 – 1.04 0.165 266 3944 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.916 0.752 – 1.12 0.383 99 1413 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.915 0.791 – 1.06 0.235 176 2796 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 0.878 0.776 – 0.993 0.039 246 3048 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 0.847 0.736 – 0.974 0.0201 183 2351 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 0.711 0.542 – 0.933 0.0139 46 569 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.769 0.614 – 0.964 0.0229 65 1078 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 0.702 0.46 – 1.07 0.101 15 445 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.963 0.927 – 1 0.06 2698 35492 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.973 0.934 – 1.01 0.192 2421 32196 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.01 0.95 – 1.08 0.704 1023 12060 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.01 0.796 – 1.28 0.939 72 897 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.921 0.832 – 1.02 0.115 379 4404 exclusion phecode
716 Other arthropathies Musculoskeletal 0.964 0.952 – 0.977 1.17e-07 23477 196989 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 0.954 0.913 – 0.997 0.0361 2074 25167 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.966 0.946 – 0.986 0.000931 9596 111168 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 0.965 0.952 – 0.979 3.93e-07 22494 194363 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.959 0.884 – 1.04 0.307 598 7700 exclusion phecode
720 Spinal stenosis Musculoskeletal 0.945 0.905 – 0.986 0.00928 2203 25800 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 0.982 0.954 – 1.01 0.22 4838 55921 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.974 0.94 – 1.01 0.16 3110 35929 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.01 0.834 – 1.22 0.937 109 1333 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 1.03 0.894 – 1.18 0.693 211 2495 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 0.962 0.937 – 0.987 0.0033 6074 66959 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.976 0.877 – 1.09 0.65 377 3878 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 0.942 0.899 – 0.988 0.014 1811 21082 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.01 0.751 – 1.35 0.962 47 524 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.954 0.919 – 0.99 0.0136 2998 32921 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 0.889 0.797 – 0.991 0.034 335 3762 exclusion phecode
723.1 Torticollis Musculoskeletal 0.828 0.668 – 1.02 0.083 79 818 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 0.963 0.912 – 1.02 0.175 1386 15228 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1.02 0.908 – 1.15 0.731 307 3198 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 1.03 0.914 – 1.16 0.646 311 3212 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 0.882 0.651 – 1.19 0.417 39 439 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 0.949 0.892 – 1.01 0.0965 1061 11786 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.991 0.971 – 1.01 0.38 10176 107805 exclusion phecode
726.1 Enthesopathy Musculoskeletal 0.99 0.965 – 1.01 0.416 6550 69785 exclusion phecode
726.2 Synoviopathy Musculoskeletal 1.12 0.981 – 1.27 0.0955 266 2591 exclusion phecode
726.3 Bursitis Musculoskeletal 0.961 0.884 – 1.05 0.358 564 6223 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 0.987 0.96 – 1.02 0.383 5229 54739 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1.01 0.959 – 1.05 0.81 1873 20440 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.981 0.785 – 1.23 0.864 77 733 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.997 0.955 – 1.04 0.89 2325 23560 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 0.905 0.819 – 1 0.0521 375 4137 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1 0.88 – 1.15 0.949 242 2529 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.982 0.797 – 1.21 0.863 99 1022 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.01 0.966 – 1.05 0.763 2465 24188 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.88 0.787 – 0.984 0.0251 308 3266 exclusion phecode
728.7 Fasciitis Musculoskeletal 1 0.961 – 1.04 0.991 2559 25266 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.01 0.968 – 1.05 0.645 2348 22728 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 0.955 0.924 – 0.988 0.00776 3620 44027 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.968 0.894 – 1.05 0.431 655 7817 exclusion phecode
729.3 Panniculitis Musculoskeletal 1.04 0.824 – 1.31 0.741 77 746 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.947 0.817 – 1.1 0.468 196 2119 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.946 0.814 – 1.1 0.469 186 2012 exclusion phecode
732 Osteochondropathies Musculoskeletal 1.01 0.899 – 1.13 0.914 344 3573 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.08 0.904 – 1.28 0.409 145 1541 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.907 0.674 – 1.22 0.519 43 451 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.987 0.93 – 1.05 0.661 1196 13157 exclusion phecode
733.2 Cyst of bone Musculoskeletal 0.993 0.864 – 1.14 0.924 225 2302 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.952 0.849 – 1.07 0.395 316 3935 exclusion phecode
733.6 Costochondritis Musculoskeletal 0.92 0.746 – 1.13 0.433 85 939 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.994 0.925 – 1.07 0.88 820 9217 exclusion phecode
733.9 Chondromalacia Musculoskeletal 1.18 0.95 – 1.46 0.135 93 930 exclusion phecode
735 Acquired foot deformities Musculoskeletal 0.992 0.968 – 1.02 0.531 6982 71984 exclusion phecode
735.1 Flat foot Musculoskeletal 0.951 0.796 – 1.14 0.578 122 1423 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 0.981 0.948 – 1.02 0.271 3551 37254 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 0.954 0.903 – 1.01 0.0986 1329 14089 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.992 0.934 – 1.05 0.809 1142 11378 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.993 0.964 – 1.02 0.637 4947 50311 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 0.991 0.929 – 1.06 0.784 1006 11671 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 0.988 0.843 – 1.16 0.886 171 1820 exclusion phecode
737 Curvature of spine Musculoskeletal 0.992 0.918 – 1.07 0.832 691 8211 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.991 0.914 – 1.07 0.82 649 7702 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.02 0.962 – 1.08 0.509 1249 13821 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 1.06 0.991 – 1.13 0.088 955 10770 exclusion phecode
739 Contracture of joint Musculoskeletal 1.02 0.905 – 1.14 0.797 306 3667 exclusion phecode
740 Osteoarthrosis Musculoskeletal 0.965 0.95 – 0.98 7.17e-06 17376 166682 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.963 0.945 – 0.982 0.000111 11040 119049 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.962 0.937 – 0.989 0.00543 5522 62406 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.954 0.836 – 1.09 0.483 227 2490 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.991 0.888 – 1.11 0.866 343 4215 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.969 0.947 – 0.992 0.00856 7456 87250 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 0.964 0.924 – 1.01 0.0859 2324 25926 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.904 0.706 – 1.16 0.421 68 725 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 0.967 0.878 – 1.06 0.491 450 4582 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 0.883 0.713 – 1.09 0.252 79 1092 exclusion phecode
741.4 Joint effusions Musculoskeletal 0.938 0.876 – 1.01 0.072 843 10050 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 0.82 0.647 – 1.04 0.1 68 795 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 1.21 0.862 – 1.71 0.266 37 413 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.964 0.922 – 1.01 0.11 2079 21769 exclusion phecode
742.1 Loose body in joint Musculoskeletal 0.869 0.764 – 0.987 0.0311 236 2417 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.04 0.818 – 1.32 0.751 75 790 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 0.891 0.799 – 0.993 0.037 350 3839 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.992 0.941 – 1.05 0.778 1489 15364 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 0.972 0.944 – 1 0.0543 4923 54050 exclusion phecode
743.1 Osteoporosis Musculoskeletal 0.984 0.953 – 1.02 0.311 4147 45488 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 0.986 0.953 – 1.02 0.409 3611 39824 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 0.953 0.853 – 1.07 0.401 319 3471 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 0.964 0.854 – 1.09 0.558 281 3692 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 0.905 0.833 – 0.982 0.0169 583 6068 exclusion phecode
745 Pain in joint Musculoskeletal 0.978 0.951 – 1.01 0.12 5204 58798 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 1.05 0.994 – 1.1 0.0819 1632 19231 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 1.05 0.992 – 1.1 0.0951 1509 17983 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 1.11 1 – 1.24 0.0436 413 4430 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.03 0.87 – 1.22 0.738 152 1731 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.01 0.944 – 1.08 0.792 929 11802 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.05 0.872 – 1.26 0.613 116 1230 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.805 0.581 – 1.11 0.192 35 360 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.89 0.777 – 1.02 0.0942 226 2300 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 1.03 0.932 – 1.14 0.573 420 4857 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.97 0.846 – 1.11 0.668 206 2222 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 1.09 0.908 – 1.31 0.347 122 1296 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.06 0.923 – 1.22 0.396 210 2597 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.09 0.926 – 1.28 0.299 158 1622 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.11 0.83 – 1.5 0.469 46 877 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 1.04 0.973 – 1.12 0.239 905 11418 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.1 1 – 1.2 0.0474 537 5406 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 1.05 0.942 – 1.17 0.373 372 3782 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.14 0.96 – 1.35 0.136 155 1519 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.962 0.868 – 1.07 0.461 370 6043 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 0.833 0.708 – 0.981 0.0282 133 3003 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.978 0.847 – 1.13 0.761 186 2457 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 1.18 1.02 – 1.36 0.0239 231 2580 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.08 0.923 – 1.26 0.336 180 2025 exclusion phecode
752.11 Spina bifida Congenital Anomalies 1.14 0.951 – 1.36 0.159 145 1665 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 1.37 1.01 – 1.87 0.045 54 593 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.888 0.708 – 1.11 0.302 81 953 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.931 0.698 – 1.24 0.625 47 581 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.06 0.838 – 1.34 0.627 72 859 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.968 0.861 – 1.09 0.58 306 3285 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.968 0.819 – 1.14 0.7 153 1554 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 1.04 0.859 – 1.27 0.671 114 1299 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.13 0.883 – 1.44 0.337 76 870 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.02 0.92 – 1.12 0.739 414 4400 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.01 0.781 – 1.31 0.923 60 635 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.995 0.884 – 1.12 0.933 297 3254 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.829 0.674 – 1.02 0.0756 88 1308 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.853 0.625 – 1.16 0.317 36 648 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1 0.843 – 1.19 0.977 133 1586 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.938 0.74 – 1.19 0.598 64 704 exclusion phecode
760 Back pain Symptoms 0.965 0.943 – 0.989 0.00367 7241 82599 exclusion phecode
761 Cervicalgia Symptoms 1.02 0.958 – 1.08 0.59 1226 13386 exclusion phecode
764 Sciatica Symptoms 0.98 0.931 – 1.03 0.446 1561 17542 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.962 0.893 – 1.03 0.296 749 8615 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 0.899 0.816 – 0.992 0.0334 414 4712 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.03 0.946 – 1.12 0.492 563 6326 exclusion phecode
771.1 Swelling of limb Symptoms 0.953 0.917 – 0.991 0.0164 2688 33176 exclusion phecode
772 Symptoms of the muscles Symptoms 0.947 0.859 – 1.04 0.278 423 4807 exclusion phecode
773 Pain in limb Symptoms 1 0.97 – 1.04 0.884 3953 45671 exclusion phecode
780 Hypothermia/Chills Symptoms 1 0.816 – 1.23 0.985 97 1231 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 0.938 0.885 – 0.994 0.0312 1200 13658 exclusion phecode
782.3 Edema Symptoms 0.943 0.877 – 1.01 0.111 745 11377 exclusion phecode
782.6 Pallor and flushing Symptoms 1.05 0.866 – 1.26 0.64 119 1247 exclusion phecode
783 Fever of unknown origin Symptoms 0.965 0.926 – 1.01 0.0886 2439 28217 exclusion phecode
785 Abdominal pain Symptoms 0.989 0.977 – 1 0.0883 28423 225671 exclusion phecode
788 Syncope and collapse Symptoms 1 0.973 – 1.03 0.986 5658 63507 exclusion phecode
789 Nausea and vomiting Symptoms 0.986 0.963 – 1.01 0.259 7405 85578 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 0.945 0.768 – 1.16 0.596 87 1038 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 1.26 0.89 – 1.79 0.192 38 573 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 0.975 0.943 – 1.01 0.128 3644 41750 exclusion phecode
791 Gangrene Symptoms 0.939 0.829 – 1.06 0.326 244 3880 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1.01 0.798 – 1.28 0.94 76 727 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.986 0.793 – 1.22 0.896 85 945 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.03 0.922 – 1.15 0.589 349 3993 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 1.19 0.961 – 1.48 0.11 96 1018 exclusion phecode
797 Shock Symptoms 0.892 0.721 – 1.1 0.288 77 1011 exclusion phecode
797.1 Cardiogenic shock Symptoms 0.958 0.723 – 1.27 0.768 46 639 exclusion phecode
798 Malaise and fatigue Symptoms 0.997 0.954 – 1.04 0.892 2176 24992 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1.01 0.912 – 1.11 0.907 447 4590 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 0.979 0.95 – 1.01 0.146 4863 50960 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.983 0.927 – 1.04 0.577 1178 12464 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.854 0.708 – 1.03 0.101 105 1222 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 0.948 0.901 – 0.998 0.0413 1569 16175 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.927 0.85 – 1.01 0.0904 532 5519 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.993 0.943 – 1.05 0.804 1561 16475 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 0.956 0.904 – 1.01 0.118 1313 13664 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 0.977 0.891 – 1.07 0.628 488 5176 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 0.988 0.962 – 1.01 0.367 6088 61074 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 0.984 0.926 – 1.05 0.597 1139 12241 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 0.981 0.95 – 1.01 0.261 3930 38861 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 0.981 0.923 – 1.04 0.535 1111 10928 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 1.01 0.966 – 1.05 0.758 2464 24889 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.988 0.924 – 1.06 0.717 927 9901 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.05 0.96 – 1.15 0.283 526 5437 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.98 0.915 – 1.05 0.569 887 9451 exclusion phecode
817 Concussion Injuries & Poisonings 0.884 0.763 – 1.02 0.101 180 1822 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.908 0.814 – 1.01 0.0817 333 3559 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 0.966 0.925 – 1.01 0.116 2173 22133 exclusion phecode
823 Torus fracture Injuries & Poisonings 0.933 0.881 – 0.988 0.0174 1226 12588 exclusion phecode
830 Dislocation Injuries & Poisonings 1.01 0.956 – 1.06 0.79 1519 15494 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.989 0.97 – 1.01 0.258 10995 112652 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 0.963 0.866 – 1.07 0.483 366 3840 exclusion phecode
840 Sprains and strains Injuries & Poisonings 1 0.903 – 1.12 0.949 358 3560 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 0.974 0.941 – 1.01 0.138 3428 38344 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.01 0.819 – 1.25 0.914 94 1115 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.03 0.914 – 1.17 0.589 276 3525 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.982 0.918 – 1.05 0.608 866 12213 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.03 0.956 – 1.11 0.417 734 8833 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1 0.954 – 1.05 0.984 1936 22544 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 0.983 0.94 – 1.03 0.469 2013 23394 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 0.754 0.562 – 1.01 0.0596 40 530 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.991 0.95 – 1.03 0.665 2338 25149 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 1.04 0.895 – 1.22 0.587 183 1967 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 0.958 0.795 – 1.15 0.65 125 1439 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.973 0.93 – 1.02 0.241 1943 20767 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.969 0.822 – 1.14 0.711 148 1535 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 1.19 0.89 – 1.6 0.237 48 511 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 0.988 0.951 – 1.03 0.53 2888 29962 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.935 0.692 – 1.26 0.66 41 369 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 0.832 0.644 – 1.08 0.16 62 656 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.952 0.796 – 1.14 0.588 118 1315 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 0.995 0.893 – 1.11 0.931 349 3368 exclusion phecode
873 Broken tooth Injuries & Poisonings 0.885 0.756 – 1.03 0.126 158 1673 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 0.942 0.766 – 1.16 0.576 87 1237 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 0.872 0.719 – 1.06 0.161 113 1185 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 0.988 0.924 – 1.06 0.736 910 9756 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 0.981 0.944 – 1.02 0.343 2732 30875 exclusion phecode
916 Contusion Injuries & Poisonings 0.947 0.888 – 1.01 0.103 958 10427 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 1.11 0.926 – 1.33 0.26 134 1399 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.978 0.861 – 1.11 0.738 250 2641 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 1.06 0.907 – 1.24 0.459 168 1712 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.976 0.923 – 1.03 0.376 1350 15276 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 0.915 0.778 – 1.08 0.289 152 1568 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.05 0.81 – 1.35 0.728 62 732 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.96 0.858 – 1.07 0.469 333 4070 exclusion phecode
947 Urticaria Injuries & Poisonings 0.913 0.805 – 1.03 0.153 249 2770 exclusion phecode
949 Allergies, other Injuries & Poisonings 1.03 0.911 – 1.17 0.621 280 3065 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 1.06 0.94 – 1.2 0.343 296 3088 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1 0.855 – 1.18 0.963 158 1935 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.969 0.864 – 1.09 0.591 310 3587 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 0.863 0.614 – 1.21 0.395 30 385 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 1.43 1.05 – 1.94 0.0245 51 506 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.972 0.954 – 0.99 0.00252 12268 135935 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.969 0.95 – 0.988 0.00176 10735 118729 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 0.985 0.867 – 1.12 0.819 253 3125 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1.02 0.94 – 1.12 0.587 575 6701 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.898 0.781 – 1.03 0.134 192 2752 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 0.891 0.774 – 1.03 0.112 188 2693 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 1.07 0.901 – 1.27 0.441 148 1787 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 0.909 0.766 – 1.08 0.278 121 1978 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 0.873 0.732 – 1.04 0.131 116 1929 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.991 0.96 – 1.02 0.6 3968 45867 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.963 0.894 – 1.04 0.315 758 8661 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.92 0.824 – 1.03 0.141 334 3867 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 1.11 0.971 – 1.26 0.129 253 2948 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.955 0.856 – 1.07 0.414 347 4037 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.924 0.834 – 1.02 0.126 404 4411 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 0.964 0.912 – 1.02 0.202 1325 15609 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.02 0.848 – 1.24 0.809 121 1510 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.995 0.844 – 1.17 0.956 157 2049 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.08 0.809 – 1.45 0.588 51 670 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 0.783 0.615 – 0.998 0.048 66 835 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 0.812 0.599 – 1.1 0.178 35 711 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 1.28 0.922 – 1.77 0.141 41 509 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.957 0.687 – 1.34 0.798 39 449 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.08 0.902 – 1.28 0.413 143 1740 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.03 0.937 – 1.14 0.52 458 5403 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.02 0.858 – 1.21 0.848 136 1611 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.17 0.861 – 1.58 0.32 45 460 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 0.943 0.735 – 1.21 0.648 61 764 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 1.21 0.958 – 1.53 0.111 86 877 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 1.06 0.802 – 1.39 0.702 53 617 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 0.992 0.947 – 1.04 0.718 2013 21824 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 0.992 0.943 – 1.04 0.755 1560 21063 exclusion phecode
994.2 Sepsis Injuries & Poisonings 0.992 0.943 – 1.04 0.755 1560 21063 exclusion phecode
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