Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Estimated glomerular filtration rate based on cystatin C UK Biobank (UKB) PheWAS analysis

Estimated glomerular filtration rate based on cystatin C — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID exprsweb-egfr-cystatinc-egfrcys-overall-ea-dbslmm-ukb-20211120Legacy DBSLMMDBSLMMLarge GWAS

Evaluation cohort: UK Biobank (UKB).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: study-defined normal-range subset.

For this ExPRS, the exclusion sensitivity scan keeps only the study-defined normal-range subset for Estimated glomerular filtration rate based on cystatin C before rerunning the PheWAS. The preserved release does not include numeric bounds for this trait. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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Signal overview

The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.

97 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.02 0.995 – 1.04 0.129 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 1 0.963 – 1.04 0.914 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.04 0.956 – 1.12 0.389 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 1.02 0.953 – 1.09 0.547 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 0.97 0.743 – 1.27 0.82 55 550 all phecode
010 Tuberculosis Infectious Diseases 0.969 0.826 – 1.14 0.697 166 1659 all phecode
038 Septicemia Infectious Diseases 1.02 0.987 – 1.05 0.246 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.01 0.941 – 1.08 0.776 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.01 0.918 – 1.1 0.884 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 1.02 0.997 – 1.03 0.11 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.06 1.02 – 1.09 0.00338 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 1 0.952 – 1.05 0.968 1641 16433 all phecode
041.4 E. coli Infectious Diseases 1.05 1.01 – 1.09 0.0163 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 0.955 0.861 – 1.06 0.38 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.809 0.646 – 1.01 0.0649 95 949 all phecode
054 Herpes simplex Infectious Diseases 1.05 0.912 – 1.2 0.52 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 1 0.92 – 1.09 0.979 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 1.03 0.811 – 1.3 0.819 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 1.01 0.848 – 1.19 0.944 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.05 0.924 – 1.19 0.461 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 0.884 0.775 – 1.01 0.065 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 0.975 0.884 – 1.07 0.607 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.09 0.923 – 1.28 0.318 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.06 0.884 – 1.28 0.523 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 0.995 0.933 – 1.06 0.887 1004 10036 all phecode
079 Viral infection Infectious Diseases 0.99 0.952 – 1.03 0.613 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 0.945 0.735 – 1.21 0.658 64 640 all phecode
080 Postoperative infection Infectious Diseases 1.01 0.982 – 1.04 0.438 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.04 1 – 1.09 0.037 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.909 0.703 – 1.18 0.468 71 709 all phecode
1000 Burns Injuries & Poisonings 0.953 0.874 – 1.04 0.28 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 1.06 1 – 1.13 0.0374 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.01 0.983 – 1.04 0.464 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.03 0.923 – 1.16 0.56 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 1.04 0.989 – 1.1 0.119 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 0.999 0.878 – 1.14 0.983 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 1.01 0.89 – 1.14 0.904 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 0.995 0.934 – 1.06 0.89 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 1.02 0.993 – 1.04 0.186 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 1.01 0.98 – 1.03 0.639 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1 0.981 – 1.02 0.83 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 1.01 0.832 – 1.24 0.886 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.08 0.965 – 1.21 0.183 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.17 0.929 – 1.48 0.18 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 0.969 0.938 – 1 0.054 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.02 1 – 1.03 0.0452 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.06 0.935 – 1.19 0.382 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 1.06 0.942 – 1.2 0.319 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.07 0.848 – 1.34 0.577 74 756 all phecode
110.12 Althete's foot Infectious Diseases 0.995 0.839 – 1.18 0.957 141 1410 all phecode
112 Candidiasis Infectious Diseases 0.976 0.933 – 1.02 0.29 2126 21275 all phecode
117 Mycoses Infectious Diseases 1.04 0.926 – 1.18 0.478 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 1.09 0.937 – 1.28 0.257 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 1.01 0.803 – 1.26 0.963 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 0.942 0.737 – 1.2 0.633 69 689 all phecode
134 Helminthiases Infectious Diseases 1.03 0.86 – 1.23 0.773 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 1.02 0.835 – 1.24 0.861 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.04 0.907 – 1.2 0.548 205 2050 all phecode
145 Cancer of mouth Neoplasms 0.989 0.912 – 1.07 0.795 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 0.953 0.847 – 1.07 0.428 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.03 0.848 – 1.26 0.748 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 0.959 0.73 – 1.26 0.765 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.892 0.819 – 0.971 0.00802 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 0.853 0.743 – 0.979 0.0234 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 0.936 0.825 – 1.06 0.311 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.858 0.649 – 1.13 0.283 57 570 all phecode
150 Cancer of esophagus Neoplasms 0.914 0.846 – 0.988 0.0229 762 7630 all phecode
151 Cancer of stomach Neoplasms 0.999 0.916 – 1.09 0.987 569 5696 all phecode
153 Colorectal cancer Neoplasms 0.987 0.957 – 1.02 0.392 4580 45799 all phecode
153.2 Colon cancer Neoplasms 1 0.964 – 1.04 1 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.957 0.916 – 1 0.0566 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.973 0.878 – 1.08 0.608 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1 0.853 – 1.18 0.983 158 1580 all phecode
157 Pancreatic cancer Neoplasms 0.976 0.9 – 1.06 0.553 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.985 0.924 – 1.05 0.64 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.975 0.948 – 1 0.07 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.953 0.821 – 1.11 0.531 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.889 0.767 – 1.03 0.118 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.981 0.847 – 1.14 0.801 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 1.3 1.02 – 1.66 0.0325 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 0.997 0.96 – 1.04 0.895 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.02 0.979 – 1.07 0.322 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 1.07 0.975 – 1.18 0.145 437 4364 all phecode
170.1 Bone cancer Neoplasms 1.25 1.05 – 1.48 0.0116 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 1.02 0.91 – 1.14 0.747 331 3303 all phecode
172 Skin cancer Neoplasms 0.989 0.972 – 1.01 0.224 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.968 0.93 – 1.01 0.113 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 0.969 0.931 – 1.01 0.122 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.988 0.968 – 1.01 0.217 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.06 0.981 – 1.15 0.138 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.923 0.79 – 1.08 0.319 181 1818 all phecode
174 Breast cancer Neoplasms 1 0.983 – 1.02 0.923 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 1 0.982 – 1.02 0.978 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.995 0.976 – 1.01 0.622 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.13 0.949 – 1.35 0.165 115 1148 all phecode
175 Acquired absence of breast Neoplasms 0.981 0.941 – 1.02 0.374 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 0.981 0.938 – 1.03 0.406 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 0.99 0.874 – 1.12 0.88 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.967 0.923 – 1.01 0.146 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 0.965 0.91 – 1.02 0.231 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 0.999 0.945 – 1.06 0.981 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.01 0.942 – 1.07 0.86 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1 0.938 – 1.07 0.921 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.92 0.815 – 1.04 0.178 305 3049 all phecode
185 Cancer of prostate Neoplasms 1.03 1 – 1.05 0.0502 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 1.04 0.943 – 1.14 0.459 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.26 1 – 1.59 0.0487 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.99 0.878 – 1.11 0.864 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.01 0.834 – 1.22 0.929 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.01 0.975 – 1.04 0.7 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.01 0.95 – 1.08 0.727 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1 0.943 – 1.07 0.881 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.1 0.861 – 1.41 0.439 66 660 all phecode
189.2 Cancer of bladder Neoplasms 1 0.962 – 1.05 0.88 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.992 0.949 – 1.04 0.726 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1 0.845 – 1.18 0.998 144 1439 all phecode
190 Cancer of eye Neoplasms 0.849 0.721 – 1 0.0503 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.982 0.908 – 1.06 0.657 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1.03 0.945 – 1.12 0.507 566 5650 all phecode
191.11 Cancer of brain Neoplasms 1.02 0.936 – 1.12 0.608 525 5240 all phecode
193 Thyroid cancer Neoplasms 1.12 1.01 – 1.24 0.0363 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 0.914 0.737 – 1.13 0.408 95 949 all phecode
195 Cancer, suspected or other Neoplasms 0.99 0.975 – 1.01 0.224 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 0.988 0.972 – 1 0.135 16267 159497 all phecode
197 Chemotherapy Neoplasms 1.01 0.994 – 1.02 0.279 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 1 0.979 – 1.02 0.967 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1 0.974 – 1.03 0.915 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.987 0.945 – 1.03 0.55 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.998 0.947 – 1.05 0.934 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.01 0.966 – 1.05 0.798 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.983 0.915 – 1.06 0.643 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.02 0.978 – 1.07 0.328 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.864 0.737 – 1.01 0.0704 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 0.964 0.912 – 1.02 0.2 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 0.94 0.761 – 1.16 0.567 95 950 all phecode
200 Myeloproliferative disease Neoplasms 1.02 0.955 – 1.09 0.571 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 1.1 0.996 – 1.22 0.0609 387 3867 all phecode
201 Hodgkin's disease Neoplasms 0.966 0.849 – 1.1 0.593 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.01 0.97 – 1.06 0.564 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.01 0.965 – 1.06 0.617 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 1.17 1.06 – 1.3 0.00218 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 1.03 0.951 – 1.12 0.434 581 5824 all phecode
204 Leukemia Neoplasms 0.991 0.942 – 1.04 0.717 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 0.973 0.893 – 1.06 0.535 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.06 0.797 – 1.41 0.691 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.956 0.872 – 1.05 0.344 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 1.01 0.915 – 1.11 0.891 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.995 0.889 – 1.11 0.924 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.09 0.924 – 1.28 0.31 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 0.97 0.888 – 1.06 0.499 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 0.995 0.98 – 1.01 0.478 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.935 0.874 – 1 0.0487 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.04 1.01 – 1.07 0.00359 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.994 0.889 – 1.11 0.92 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.05 0.935 – 1.18 0.418 318 3187 all phecode
214 Lipoma Neoplasms 1.01 0.986 – 1.04 0.355 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.02 0.988 – 1.05 0.231 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.07 1.01 – 1.14 0.0201 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 1.01 0.988 – 1.04 0.324 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.03 0.949 – 1.11 0.508 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.02 0.942 – 1.11 0.599 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 0.997 0.977 – 1.02 0.768 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 0.993 0.973 – 1.01 0.516 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.928 0.831 – 1.04 0.182 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 0.996 0.943 – 1.05 0.883 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.945 0.821 – 1.09 0.43 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 1.22 1.04 – 1.42 0.0121 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.11 0.954 – 1.28 0.179 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 1.06 0.891 – 1.26 0.51 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.16 0.916 – 1.47 0.219 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.93 0.863 – 1 0.0563 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.94 0.871 – 1.01 0.11 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.815 0.606 – 1.1 0.177 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.925 0.813 – 1.05 0.238 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.05 0.978 – 1.12 0.19 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.07 0.923 – 1.23 0.383 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.11 1 – 1.23 0.0472 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1 0.888 – 1.13 0.99 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.973 0.924 – 1.02 0.299 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.04 0.997 – 1.08 0.0687 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.05 0.967 – 1.14 0.241 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.943 0.885 – 1 0.0702 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.03 0.934 – 1.13 0.585 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.898 0.828 – 0.975 0.0104 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.02 0.973 – 1.07 0.411 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 0.974 0.885 – 1.07 0.586 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 0.949 0.772 – 1.17 0.616 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.01 0.852 – 1.21 0.869 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 1.01 0.998 – 1.03 0.0929 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.05 0.986 – 1.11 0.134 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.875 0.702 – 1.09 0.236 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.01 0.994 – 1.03 0.212 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 0.901 0.796 – 1.02 0.103 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.922 0.801 – 1.06 0.26 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.924 0.8 – 1.07 0.278 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 0.99 0.893 – 1.1 0.851 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 0.996 0.981 – 1.01 0.571 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.976 0.938 – 1.02 0.228 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.864 0.751 – 0.994 0.0412 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.02 0.812 – 1.27 0.883 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.98 0.893 – 1.08 0.676 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 0.997 0.851 – 1.17 0.969 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.992 0.977 – 1.01 0.309 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.1 0.911 – 1.34 0.312 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.19 1.04 – 1.36 0.013 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.01 0.946 – 1.08 0.779 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.02 0.935 – 1.12 0.612 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 0.971 0.897 – 1.05 0.476 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.02 0.902 – 1.16 0.737 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.957 0.864 – 1.06 0.404 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.94 0.781 – 1.13 0.516 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.05 0.944 – 1.17 0.371 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.993 0.939 – 1.05 0.813 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 0.952 0.889 – 1.02 0.157 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.08 1.01 – 1.15 0.0349 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.07 0.995 – 1.15 0.0697 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.14 0.968 – 1.34 0.117 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.03 0.952 – 1.11 0.472 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.05 0.902 – 1.21 0.557 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.22 1 – 1.48 0.0501 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.969 0.852 – 1.1 0.635 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.809 0.64 – 1.02 0.0757 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.11 0.955 – 1.3 0.17 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.98 0.903 – 1.06 0.636 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.05 0.905 – 1.22 0.512 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.945 0.77 – 1.16 0.591 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.18 0.944 – 1.48 0.144 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.02 0.916 – 1.14 0.712 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.02 0.916 – 1.14 0.697 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 1.01 0.886 – 1.15 0.868 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.984 0.855 – 1.13 0.827 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 1.1 0.936 – 1.28 0.257 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.09 0.924 – 1.28 0.311 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.963 0.789 – 1.17 0.707 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 0.974 0.82 – 1.16 0.764 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 1.01 0.879 – 1.16 0.889 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 0.93 0.688 – 1.26 0.633 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 0.973 0.906 – 1.05 0.455 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 0.999 0.942 – 1.06 0.986 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.03 0.953 – 1.1 0.501 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.01 0.918 – 1.11 0.833 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.999 0.795 – 1.26 0.994 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.989 0.867 – 1.13 0.874 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 1.09 0.974 – 1.21 0.135 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.05 0.938 – 1.18 0.397 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.08 0.955 – 1.22 0.226 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 1.05 0.911 – 1.21 0.503 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 0.966 0.798 – 1.17 0.718 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.1 0.873 – 1.39 0.411 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.08 0.925 – 1.27 0.323 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.07 0.904 – 1.27 0.427 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.998 0.986 – 1.01 0.692 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.998 0.986 – 1.01 0.675 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.998 0.987 – 1.01 0.783 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.982 0.746 – 1.29 0.897 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.06 0.907 – 1.24 0.465 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.06 0.928 – 1.22 0.374 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.03 0.996 – 1.06 0.0871 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 1.02 0.98 – 1.05 0.392 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.16 0.96 – 1.4 0.126 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.08 0.997 – 1.17 0.0601 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.1 1.01 – 1.19 0.037 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.06 1.02 – 1.11 0.00586 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 1.04 0.963 – 1.13 0.3 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.11 0.999 – 1.23 0.0521 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.07 1.01 – 1.13 0.0242 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.04 0.886 – 1.22 0.645 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.02 0.999 – 1.05 0.0653 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.04 1 – 1.07 0.0235 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.08 0.953 – 1.23 0.22 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.01 0.964 – 1.06 0.641 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.04 0.973 – 1.11 0.255 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.07 1.02 – 1.13 0.0106 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.99 0.932 – 1.05 0.755 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 1.01 0.945 – 1.07 0.842 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 0.899 0.732 – 1.1 0.306 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 1.01 0.967 – 1.04 0.786 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 1.05 0.954 – 1.15 0.326 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 0.97 0.808 – 1.16 0.744 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.02 0.955 – 1.09 0.529 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 1.02 0.918 – 1.13 0.721 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.04 0.912 – 1.19 0.553 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.07 0.806 – 1.43 0.634 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.02 0.996 – 1.04 0.125 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 1.02 0.997 – 1.04 0.0893 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 0.869 0.695 – 1.09 0.221 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.1 0.858 – 1.4 0.458 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.11 0.976 – 1.25 0.113 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1.12 0.983 – 1.28 0.088 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.2 1.02 – 1.42 0.0292 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.07 0.936 – 1.21 0.339 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 1.01 0.989 – 1.04 0.319 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.01 0.988 – 1.04 0.331 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.03 0.939 – 1.14 0.501 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 1.05 0.986 – 1.11 0.136 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 1.05 0.982 – 1.11 0.163 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 1.03 0.955 – 1.11 0.457 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.2 1.03 – 1.38 0.0171 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 1.03 0.888 – 1.2 0.675 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 1.12 0.858 – 1.45 0.415 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.03 0.874 – 1.21 0.75 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 0.991 0.756 – 1.3 0.95 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.06 0.858 – 1.32 0.579 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.06 0.894 – 1.26 0.507 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.993 0.814 – 1.21 0.946 103 1059 all phecode
284 Aplastic anemia Hematopoietic 1.06 0.966 – 1.17 0.212 435 4357 all phecode
285 Other anemias Hematopoietic 1.01 0.994 – 1.03 0.189 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.991 0.874 – 1.12 0.883 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.04 0.964 – 1.12 0.304 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.07 0.971 – 1.18 0.172 414 4147 all phecode
286 Coagulation defects Hematopoietic 0.978 0.913 – 1.05 0.53 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 0.942 0.852 – 1.04 0.243 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 0.887 0.708 – 1.11 0.3 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.921 0.813 – 1.04 0.194 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.02 0.797 – 1.31 0.864 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.15 0.936 – 1.42 0.181 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.983 0.885 – 1.09 0.746 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.03 0.979 – 1.08 0.255 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.05 0.884 – 1.26 0.554 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 1.14 0.876 – 1.48 0.334 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 1.02 0.968 – 1.07 0.465 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 0.911 0.821 – 1.01 0.0782 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.856 0.664 – 1.1 0.229 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 1.01 0.978 – 1.05 0.525 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 0.995 0.959 – 1.03 0.784 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 0.994 0.958 – 1.03 0.739 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 1.23 0.98 – 1.55 0.0745 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.01 0.944 – 1.09 0.729 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.948 0.839 – 1.07 0.387 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 1.02 0.977 – 1.06 0.418 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 0.953 0.87 – 1.04 0.304 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.02 0.907 – 1.15 0.722 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.13 0.917 – 1.39 0.253 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1 0.954 – 1.05 0.992 1929 19281 all phecode
290.1 Dementias Mental Disorders 0.987 0.924 – 1.05 0.696 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 1.03 0.935 – 1.14 0.526 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 0.927 0.799 – 1.07 0.313 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.973 0.897 – 1.06 0.517 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.09 0.868 – 1.37 0.459 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.961 0.894 – 1.03 0.279 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.03 0.856 – 1.23 0.782 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.919 0.81 – 1.04 0.187 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 1 0.908 – 1.11 0.968 436 4376 all phecode
292 Neurological disorders Mental Disorders 1.03 1 – 1.06 0.0309 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.02 0.969 – 1.08 0.432 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.924 0.793 – 1.08 0.314 190 1907 all phecode
292.3 Memory loss Mental Disorders 1.01 0.939 – 1.1 0.725 696 6978 all phecode
292.4 Altered mental status Mental Disorders 1.04 0.996 – 1.09 0.0766 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 1.05 0.934 – 1.18 0.419 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 1.02 0.975 – 1.07 0.386 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.967 0.902 – 1.04 0.337 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.969 0.901 – 1.04 0.391 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 0.984 0.902 – 1.07 0.707 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 1.01 0.861 – 1.17 0.941 178 1780 all phecode
295.3 Psychosis Mental Disorders 0.896 0.76 – 1.06 0.195 169 1710 all phecode
296 Mood disorders Mental Disorders 1.03 1.01 – 1.05 0.00178 12372 123822 all phecode
296.1 Bipolar Mental Disorders 1.02 0.956 – 1.08 0.575 1059 10599 all phecode
296.2 Depression Mental Disorders 1.03 1.01 – 1.05 0.0017 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 1.03 0.92 – 1.14 0.648 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.914 0.81 – 1.03 0.144 311 3070 all phecode
300 Anxiety disorders Mental Disorders 1.01 0.986 – 1.04 0.393 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 1.01 0.985 – 1.04 0.41 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 0.956 0.808 – 1.13 0.604 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.02 0.94 – 1.1 0.695 707 7065 all phecode
300.13 Phobia Mental Disorders 1.01 0.924 – 1.11 0.791 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.891 0.745 – 1.07 0.209 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 1.11 0.847 – 1.45 0.455 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 1.03 0.854 – 1.24 0.778 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.03 0.851 – 1.24 0.781 113 1129 all phecode
301 Personality disorders Mental Disorders 1.16 1.05 – 1.3 0.00524 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.09 0.905 – 1.31 0.366 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 1.04 0.917 – 1.17 0.56 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 0.99 0.899 – 1.09 0.845 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 0.931 0.83 – 1.04 0.222 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 1.04 0.867 – 1.25 0.666 123 1229 all phecode
304 Adjustment reaction Mental Disorders 0.981 0.869 – 1.11 0.762 293 2936 all phecode
305.2 Eating disorder Mental Disorders 0.881 0.705 – 1.1 0.266 90 900 all phecode
306 Other mental disorder Mental Disorders 1.01 0.998 – 1.02 0.115 28056 230087 all phecode
306.9 Tension headache Mental Disorders 1.03 0.918 – 1.15 0.62 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 0.922 0.73 – 1.16 0.492 76 770 all phecode
313.3 Autism Mental Disorders 1.11 0.859 – 1.44 0.419 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 0.992 0.887 – 1.11 0.883 351 3517 all phecode
315.1 Learning disorder Mental Disorders 0.942 0.799 – 1.11 0.476 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 0.866 0.687 – 1.09 0.224 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 1 0.976 – 1.03 0.779 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.863 0.661 – 1.13 0.28 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 1 0.982 – 1.02 0.955 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 1 0.978 – 1.02 0.986 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 0.982 0.914 – 1.05 0.609 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 0.991 0.976 – 1.01 0.23 19359 185465 all phecode
320 Meningitis Neurological 0.96 0.87 – 1.06 0.416 444 4447 all phecode
323 Encephalitis Neurological 1.07 0.962 – 1.19 0.212 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 1.16 0.935 – 1.45 0.175 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.12 1 – 1.26 0.0505 292 2916 all phecode
327 Sleep disorders Neurological 1.1 1.04 – 1.17 0.000815 1164 11659 all phecode
327.3 Sleep apnea Neurological 1.01 0.976 – 1.04 0.669 4428 44318 all phecode
327.4 Insomnia Neurological 1 0.857 – 1.18 0.957 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 1.04 0.879 – 1.23 0.646 136 1390 all phecode
331 Other cerebral degenerations Neurological 1.01 0.955 – 1.08 0.639 1142 11416 all phecode
331.1 Hydrocephalus Neurological 0.988 0.9 – 1.08 0.8 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 1.07 0.966 – 1.18 0.204 430 4298 all phecode
332 Parkinson's disease Neurological 1.06 1 – 1.13 0.048 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.06 0.991 – 1.13 0.0882 894 8954 all phecode
333.1 Essential tremor Neurological 1.12 0.976 – 1.28 0.109 216 2157 all phecode
333.2 Myoclonus Neurological 1.16 0.943 – 1.43 0.16 96 958 all phecode
333.4 Torsion dystonia Neurological 0.93 0.813 – 1.06 0.294 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 1.01 0.965 – 1.06 0.588 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 1.12 0.934 – 1.35 0.222 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 1.06 0.926 – 1.2 0.417 245 2446 all phecode
335 Multiple sclerosis Neurological 1.02 0.965 – 1.08 0.475 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 1.02 0.905 – 1.16 0.701 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 0.879 0.687 – 1.12 0.302 72 719 all phecode
338 Pain Neurological 1.1 1.02 – 1.18 0.014 768 7692 all phecode
338.1 Acute pain Neurological 1.09 0.987 – 1.21 0.0877 394 3937 all phecode
338.2 Chronic pain Neurological 1.07 0.963 – 1.18 0.21 380 3817 all phecode
339 Other headache syndromes Neurological 1 0.981 – 1.03 0.74 7819 78241 all phecode
340 Migraine Neurological 0.994 0.957 – 1.03 0.778 2860 28602 all phecode
340.1 Migrain with aura Neurological 0.957 0.83 – 1.1 0.546 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.995 0.873 – 1.13 0.937 252 2535 all phecode
342 Hemiplegia Neurological 1.02 0.968 – 1.08 0.453 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 0.808 0.673 – 0.97 0.0223 145 1450 all phecode
344 Other paralytic syndromes Neurological 1.06 0.977 – 1.14 0.168 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.01 0.985 – 1.04 0.37 5023 50270 all phecode
345.1 Epilepsy Neurological 1.04 0.973 – 1.12 0.24 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 1.12 1.02 – 1.23 0.016 439 4385 all phecode
345.12 Partial epilepsy Neurological 1.04 0.922 – 1.17 0.521 277 2776 all phecode
345.3 Convulsions Neurological 0.991 0.949 – 1.03 0.689 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.07 0.912 – 1.26 0.399 144 1438 all phecode
348 Other conditions of brain Neurological 0.966 0.896 – 1.04 0.356 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 0.949 0.835 – 1.08 0.425 268 2678 all phecode
348.4 Cerebral cysts Neurological 1.04 0.875 – 1.24 0.651 133 1350 all phecode
348.7 Coma Neurological 0.979 0.878 – 1.09 0.7 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 0.961 0.84 – 1.1 0.558 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 0.957 0.862 – 1.06 0.417 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.07 0.964 – 1.19 0.198 342 3414 all phecode
350 Abnormal movement Neurological 1.04 1 – 1.09 0.0332 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 1.02 0.955 – 1.1 0.511 887 8852 all phecode
350.2 Abnormality of gait Neurological 1.05 1 – 1.11 0.0465 1596 15969 all phecode
350.3 Lack of coordination Neurological 1.05 0.947 – 1.17 0.346 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.01 0.771 – 1.31 0.966 54 540 all phecode
351 Other peripheral nerve disorders Neurological 1 0.983 – 1.02 0.926 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 1.03 0.977 – 1.09 0.252 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.993 0.903 – 1.09 0.884 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.03 0.962 – 1.1 0.393 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 0.992 0.932 – 1.05 0.788 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 0.844 0.687 – 1.04 0.106 114 1138 all phecode
353.2 Nerve root lesions Neurological 1.15 0.891 – 1.48 0.288 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.06 0.902 – 1.24 0.483 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.08 1.02 – 1.14 0.00882 1361 13648 all phecode
358 Myoneural disorders Neurological 1.05 0.914 – 1.2 0.506 211 2109 all phecode
358.1 Myasthenia gravis Neurological 1.09 0.947 – 1.25 0.232 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 1.04 0.944 – 1.14 0.448 465 4646 all phecode
359.1 Muscular dystrophies Neurological 0.856 0.704 – 1.04 0.118 122 1219 all phecode
359.2 Myopathy Neurological 1.1 0.988 – 1.22 0.0827 360 3597 all phecode
360 Disorders of the globe Sense Organs 1 0.894 – 1.12 0.999 337 3367 all phecode
360.2 Progressive myopia Sense Organs 1.05 0.926 – 1.19 0.446 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 1.02 0.986 – 1.06 0.226 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.02 0.965 – 1.08 0.503 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.925 0.719 – 1.19 0.545 68 680 all phecode
362 Other retinal disorders Sense Organs 1.01 0.976 – 1.04 0.627 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.01 0.967 – 1.05 0.654 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.01 0.967 – 1.05 0.667 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.02 0.873 – 1.2 0.783 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 1.11 0.909 – 1.34 0.317 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.03 0.959 – 1.1 0.435 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 1.01 0.869 – 1.17 0.891 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.903 0.717 – 1.14 0.389 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.979 0.81 – 1.18 0.825 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.949 0.807 – 1.11 0.523 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 1.05 0.824 – 1.33 0.707 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.02 0.946 – 1.11 0.552 647 6485 all phecode
364.1 Corneal opacity Sense Organs 1.16 0.939 – 1.43 0.171 90 910 all phecode
364.2 Corneal edema Sense Organs 1.01 0.802 – 1.27 0.926 79 800 all phecode
364.4 Corneal degenerations Sense Organs 1.12 0.977 – 1.29 0.102 201 2017 all phecode
364.41 Keratoconus Sense Organs 1.08 0.882 – 1.33 0.444 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 0.964 0.835 – 1.11 0.615 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.919 0.744 – 1.13 0.432 100 1000 all phecode
365 Glaucoma Sense Organs 0.998 0.968 – 1.03 0.904 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 1.01 0.951 – 1.08 0.689 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.01 0.951 – 1.08 0.672 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.995 0.92 – 1.08 0.896 698 6996 all phecode
366 Cataract Sense Organs 1 0.988 – 1.02 0.732 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 0.957 0.75 – 1.22 0.722 69 700 all phecode
366.2 Senile cataract Sense Organs 1 0.981 – 1.03 0.777 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 1.1 0.908 – 1.33 0.332 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.01 0.971 – 1.06 0.546 2408 24092 all phecode
367.1 Myopia Sense Organs 1.03 0.97 – 1.09 0.353 1251 12519 all phecode
367.2 Astigmatism Sense Organs 0.984 0.846 – 1.14 0.836 190 1899 all phecode
367.8 Hypermetropia Sense Organs 1.04 0.913 – 1.18 0.563 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 0.998 0.923 – 1.08 0.955 719 7198 all phecode
368 Visual disturbances Sense Organs 1.03 0.992 – 1.07 0.123 2962 29648 all phecode
368.1 Amblyopia Sense Organs 0.99 0.906 – 1.08 0.832 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.985 0.912 – 1.06 0.705 727 7288 all phecode
368.3 Anisometropia Sense Organs 1.1 0.945 – 1.29 0.213 154 1548 all phecode
368.4 Visual field defects Sense Organs 1.07 0.957 – 1.19 0.239 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 1.12 1.03 – 1.21 0.00711 612 6115 all phecode
369 Infection of the eye Sense Organs 1.06 0.967 – 1.15 0.229 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 1.01 0.834 – 1.21 0.955 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.946 0.818 – 1.09 0.452 213 2128 all phecode
370 Keratitis Sense Organs 0.989 0.875 – 1.12 0.856 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 0.951 0.802 – 1.13 0.567 141 1408 all phecode
371 Inflammation of the eye Sense Organs 1.03 0.992 – 1.07 0.13 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.04 0.949 – 1.14 0.405 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 1.02 0.976 – 1.06 0.399 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 1.01 0.936 – 1.09 0.835 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 0.994 0.968 – 1.02 0.688 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 0.948 0.889 – 1.01 0.105 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 0.982 0.935 – 1.03 0.457 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 0.992 0.95 – 1.04 0.735 2204 22031 all phecode
375.2 Epiphora Sense Organs 0.971 0.906 – 1.04 0.4 898 8969 all phecode
376 Disorders of the orbit Sense Organs 0.914 0.725 – 1.15 0.446 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.01 0.908 – 1.13 0.834 361 3618 all phecode
377.1 Optic atrophy Sense Organs 0.975 0.743 – 1.28 0.853 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.972 0.81 – 1.17 0.758 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.983 0.93 – 1.04 0.536 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.958 0.894 – 1.03 0.225 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.978 0.849 – 1.13 0.76 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 1.1 0.977 – 1.25 0.113 275 2755 all phecode
379 Other disorders of eye Sense Organs 0.988 0.955 – 1.02 0.488 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 1 0.948 – 1.06 0.946 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.992 0.945 – 1.04 0.73 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.02 0.801 – 1.29 0.895 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.05 0.952 – 1.16 0.318 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.963 0.821 – 1.13 0.643 169 1690 all phecode
380 Disorders of external ear Sense Organs 1.01 0.932 – 1.09 0.803 642 6413 all phecode
380.1 Otitis externa Sense Organs 1.02 0.93 – 1.12 0.684 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 1 0.901 – 1.11 0.983 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.979 0.936 – 1.02 0.347 2150 21493 all phecode
381.1 Otitis media Sense Organs 0.969 0.922 – 1.02 0.206 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.988 0.921 – 1.06 0.737 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 1.01 0.878 – 1.17 0.845 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.08 0.925 – 1.26 0.337 171 1709 all phecode
381.9 Otorrhea Sense Organs 0.97 0.856 – 1.1 0.632 281 2807 all phecode
382 Otalgia Sense Organs 1.1 0.981 – 1.23 0.103 308 3084 all phecode
383 Otosclerosis Sense Organs 1 0.892 – 1.13 0.973 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 1 0.949 – 1.06 0.872 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.02 0.958 – 1.09 0.519 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.02 0.948 – 1.1 0.612 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 1 0.924 – 1.09 0.923 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.03 0.902 – 1.17 0.686 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.06 1.01 – 1.12 0.0136 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 1.13 1.04 – 1.23 0.00324 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 1.01 0.905 – 1.12 0.921 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 1.01 0.94 – 1.09 0.745 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.01 0.983 – 1.04 0.393 4582 45806 all phecode
388 Other disorders of ear Sense Organs 1.16 1.01 – 1.33 0.0317 202 2017 all phecode
389 Hearing loss Sense Organs 1.01 0.974 – 1.04 0.748 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 1.04 0.951 – 1.15 0.361 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 0.945 0.855 – 1.04 0.262 450 4497 all phecode
389.4 Tinnitus Sense Organs 0.98 0.894 – 1.07 0.663 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.02 0.988 – 1.05 0.237 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 1.01 0.975 – 1.05 0.509 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 1.02 0.962 – 1.08 0.52 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.05 0.986 – 1.12 0.13 1058 10566 all phecode
395 Heart valve disorders Circulatory System 1.02 0.989 – 1.05 0.212 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.02 0.98 – 1.06 0.347 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.09 0.967 – 1.24 0.154 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.15 0.953 – 1.39 0.145 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.03 0.843 – 1.27 0.751 97 970 all phecode
395.6 Heart valve replaced Circulatory System 1 0.951 – 1.06 0.908 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 1.05 0.988 – 1.12 0.114 1048 10468 all phecode
401 Hypertension Circulatory System 1.01 0.999 – 1.02 0.087 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 1.01 0.999 – 1.02 0.0893 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.01 0.963 – 1.06 0.719 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 0.998 0.898 – 1.11 0.974 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.01 0.96 – 1.06 0.679 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 0.988 0.828 – 1.18 0.895 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.04 0.986 – 1.1 0.146 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 0.996 0.984 – 1.01 0.549 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.999 0.971 – 1.03 0.954 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 1 0.983 – 1.02 0.857 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 0.984 0.968 – 1 0.051 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 0.998 0.983 – 1.01 0.747 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.948 0.876 – 1.03 0.183 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.999 0.982 – 1.02 0.907 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.01 0.95 – 1.07 0.817 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 0.984 0.937 – 1.03 0.503 1823 18228 all phecode
414.2 ASCVD Circulatory System 1.12 0.881 – 1.42 0.363 72 719 all phecode
415 Pulmonary heart disease Circulatory System 1.02 0.985 – 1.05 0.31 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.03 0.821 – 1.29 0.803 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.07 0.988 – 1.17 0.0915 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.07 0.974 – 1.18 0.153 448 4475 all phecode
416 Cardiomegaly Circulatory System 1.01 0.969 – 1.05 0.705 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 1.01 0.993 – 1.02 0.407 28599 270106 all phecode
418.1 Precordial pain Circulatory System 1.01 0.972 – 1.04 0.738 3551 35541 all phecode
420 Carditis Circulatory System 1.03 0.987 – 1.08 0.164 2106 21053 all phecode
420.1 Myocarditis Circulatory System 1.03 0.859 – 1.23 0.762 127 1267 all phecode
420.2 Pericarditis Circulatory System 1.06 1 – 1.12 0.0364 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 1.1 0.96 – 1.25 0.176 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 1.01 0.841 – 1.22 0.882 113 1129 all phecode
420.3 Endocarditis Circulatory System 0.987 0.913 – 1.07 0.74 719 7194 all phecode
425 Cardiomyopathy Circulatory System 0.976 0.921 – 1.04 0.425 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.967 0.911 – 1.03 0.268 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.934 0.78 – 1.12 0.46 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.03 0.874 – 1.21 0.749 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 1.24 0.973 – 1.57 0.0826 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 0.981 0.957 – 1.01 0.129 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 0.964 0.921 – 1.01 0.109 2114 21162 all phecode
426.21 First degree AV block Circulatory System 0.964 0.902 – 1.03 0.273 986 9867 all phecode
426.23 Second degree AV block Circulatory System 1.01 0.915 – 1.11 0.874 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 0.994 0.914 – 1.08 0.895 587 5868 all phecode
426.25 Other heart block Circulatory System 1.06 0.886 – 1.27 0.527 131 1318 all phecode
426.3 Bundle branch block Circulatory System 0.993 0.958 – 1.03 0.679 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 1.01 0.954 – 1.06 0.824 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 0.977 0.93 – 1.03 0.357 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.956 0.834 – 1.1 0.523 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.45 1.14 – 1.84 0.00263 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.984 0.944 – 1.03 0.451 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.982 0.94 – 1.03 0.4 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 0.993 0.98 – 1.01 0.3 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1 0.964 – 1.04 0.986 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.992 0.95 – 1.04 0.708 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.01 0.948 – 1.08 0.693 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 0.995 0.978 – 1.01 0.565 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.983 0.948 – 1.02 0.361 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1.01 0.948 – 1.07 0.845 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.95 0.85 – 1.06 0.368 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 1.02 0.955 – 1.09 0.571 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.987 0.924 – 1.05 0.696 952 9541 all phecode
427.6 Premature beats Circulatory System 1.05 0.963 – 1.14 0.272 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 0.93 0.769 – 1.12 0.455 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 0.984 0.941 – 1.03 0.464 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.04 0.939 – 1.15 0.472 402 4029 all phecode
427.9 Palpitations Circulatory System 1 0.972 – 1.04 0.774 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.03 0.998 – 1.05 0.0661 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.02 0.979 – 1.07 0.313 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 1.03 0.998 – 1.06 0.0694 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.01 0.938 – 1.09 0.76 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 0.843 0.641 – 1.11 0.223 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.977 0.892 – 1.07 0.617 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.12 0.979 – 1.29 0.096 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 1.03 0.987 – 1.08 0.155 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.08 1 – 1.15 0.0415 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 0.999 0.928 – 1.08 0.981 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 1.01 0.895 – 1.14 0.845 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 0.997 0.976 – 1.02 0.809 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.01 0.957 – 1.08 0.625 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.06 0.927 – 1.21 0.393 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.984 0.953 – 1.02 0.317 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.966 0.919 – 1.02 0.183 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 0.993 0.955 – 1.03 0.714 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 0.998 0.955 – 1.04 0.934 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 0.987 0.889 – 1.1 0.813 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.996 0.94 – 1.06 0.89 1279 12783 all phecode
440 Atherosclerosis Circulatory System 0.987 0.933 – 1.04 0.634 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.01 0.832 – 1.23 0.903 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.972 0.904 – 1.05 0.446 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 0.982 0.868 – 1.11 0.773 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 0.94 0.864 – 1.02 0.15 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.89 0.783 – 1.01 0.0761 283 2827 all phecode
442 Other aneurysm Circulatory System 1.02 0.972 – 1.07 0.443 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 1.01 0.954 – 1.06 0.824 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.02 0.953 – 1.09 0.582 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.13 0.931 – 1.36 0.22 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.09 0.936 – 1.27 0.271 169 1696 all phecode
442.4 Arterial dissection Circulatory System 1.41 1.11 – 1.79 0.00514 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 0.987 0.856 – 1.14 0.856 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 1.02 0.992 – 1.06 0.139 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 1.05 0.988 – 1.11 0.117 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.992 0.893 – 1.1 0.883 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.02 0.988 – 1.06 0.212 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.01 0.972 – 1.05 0.579 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.03 0.965 – 1.1 0.357 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.04 0.953 – 1.13 0.402 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.02 0.947 – 1.09 0.658 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 1.11 0.963 – 1.27 0.152 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 1.02 0.921 – 1.13 0.68 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 1.03 0.9 – 1.17 0.684 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 0.96 0.906 – 1.02 0.158 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 1.01 0.938 – 1.08 0.884 868 8712 all phecode
448 Disease of capillaries Circulatory System 0.972 0.817 – 1.16 0.748 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.02 0.945 – 1.1 0.598 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.02 0.99 – 1.06 0.168 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.04 1 – 1.07 0.0357 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.967 0.885 – 1.06 0.458 564 5645 all phecode
454 Varicose veins Circulatory System 1.01 0.991 – 1.03 0.29 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1.01 0.992 – 1.03 0.27 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.917 0.842 – 0.998 0.0456 624 6325 all phecode
455 Hemorrhoids Circulatory System 1 0.99 – 1.02 0.65 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.957 0.821 – 1.11 0.57 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.09 0.885 – 1.33 0.432 97 967 all phecode
458 Hypotension Circulatory System 1.02 0.994 – 1.05 0.122 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 1 0.948 – 1.06 0.927 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.02 0.894 – 1.17 0.747 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 1.02 0.984 – 1.05 0.295 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 1 0.984 – 1.02 1 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 1.06 0.895 – 1.25 0.51 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 1 0.984 – 1.02 0.994 16103 159422 all phecode
464 Acute sinusitis Respiratory 1.02 0.877 – 1.18 0.837 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.981 0.94 – 1.02 0.393 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 1.02 0.946 – 1.09 0.67 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.01 0.865 – 1.18 0.916 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.03 0.998 – 1.06 0.0689 4654 46553 all phecode
471 Nasal polyps Respiratory 1.01 0.977 – 1.05 0.49 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.06 0.993 – 1.13 0.0785 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1 0.962 – 1.04 0.935 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 0.884 0.717 – 1.09 0.249 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.02 0.9 – 1.16 0.756 264 2647 all phecode
473.4 Voice disturbance Respiratory 0.982 0.922 – 1.05 0.573 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 1.02 0.976 – 1.08 0.331 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 1.09 1 – 1.19 0.0421 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.996 0.936 – 1.06 0.894 1122 11199 all phecode
475 Chronic sinusitis Respiratory 0.996 0.956 – 1.04 0.844 2589 25882 all phecode
476 Allergic rhinitis Respiratory 0.982 0.92 – 1.05 0.579 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 0.992 0.951 – 1.03 0.692 2447 24452 all phecode
478 Throat pain Respiratory 1.1 0.992 – 1.22 0.0697 377 3789 all phecode
479 Other upper respiratory disease Respiratory 1.02 0.987 – 1.05 0.257 4074 40737 all phecode
480 Pneumonia Respiratory 1.01 0.99 – 1.03 0.336 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 1.01 0.987 – 1.04 0.346 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.01 0.985 – 1.04 0.414 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.05 0.853 – 1.29 0.641 93 929 all phecode
480.2 Viral pneumonia Respiratory 0.831 0.639 – 1.08 0.166 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.03 0.84 – 1.26 0.789 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.03 0.957 – 1.11 0.447 794 7951 all phecode
481 Influenza Respiratory 1 0.893 – 1.12 0.999 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.02 0.879 – 1.19 0.784 193 1930 all phecode
495 Asthma Respiratory 0.999 0.986 – 1.01 0.878 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 0.86 0.749 – 0.987 0.0323 250 2510 all phecode
496 Chronic airway obstruction Respiratory 1 0.98 – 1.02 0.984 10424 101546 all phecode
496.1 Emphysema Respiratory 0.998 0.95 – 1.05 0.923 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 0.998 0.961 – 1.04 0.899 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 0.996 0.957 – 1.04 0.836 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 1 0.956 – 1.05 0.928 1885 18859 all phecode
497 Bronchitis Respiratory 0.933 0.856 – 1.02 0.116 626 6267 all phecode
500 Lung disease due to external agents Respiratory 1.03 0.93 – 1.14 0.591 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.925 0.733 – 1.17 0.515 79 784 all phecode
500.2 Pneumoconiosis Respiratory 1.03 0.908 – 1.17 0.622 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.02 0.938 – 1.1 0.7 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.01 0.942 – 1.08 0.826 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 0.846 0.767 – 0.933 0.000783 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.05 0.936 – 1.17 0.418 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.09 0.844 – 1.4 0.518 61 610 all phecode
506 Empyema and pneumothorax Respiratory 1 0.944 – 1.07 0.903 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 1.02 0.991 – 1.04 0.218 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.972 0.928 – 1.02 0.234 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.02 0.98 – 1.06 0.334 2599 26031 all phecode
509.1 Respiratory failure Respiratory 1.03 0.987 – 1.08 0.16 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 1.03 0.978 – 1.08 0.292 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 1.12 0.955 – 1.32 0.158 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.946 0.85 – 1.05 0.305 386 3863 all phecode
510 Other diseases of lung Respiratory 1.08 1 – 1.16 0.0405 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 1.03 1 – 1.05 0.0183 9031 90349 all phecode
512.1 Wheezing Respiratory 0.997 0.864 – 1.15 0.963 220 2196 all phecode
512.2 Painful respiration Respiratory 1.09 0.948 – 1.26 0.225 207 2075 all phecode
512.7 Shortness of breath Respiratory 1.02 0.998 – 1.05 0.0747 5842 58498 all phecode
512.8 Cough Respiratory 1.04 0.998 – 1.08 0.062 2866 28642 all phecode
512.9 Other dyspnea Respiratory 0.985 0.92 – 1.05 0.667 914 9124 all phecode
513 Respiratory abnormalities Respiratory 0.96 0.882 – 1.05 0.347 611 6112 all phecode
513.3 Hypoventilation Respiratory 1.07 0.86 – 1.34 0.528 83 830 all phecode
513.4 Hyperventilation Respiratory 0.897 0.787 – 1.02 0.103 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 1.03 0.87 – 1.21 0.766 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 1.01 0.969 – 1.05 0.659 2465 24673 all phecode
516 Abnormal sputum Respiratory 1 0.96 – 1.05 0.869 2132 21335 all phecode
516.1 Hemoptysis Respiratory 1.01 0.962 – 1.05 0.767 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.994 0.973 – 1.02 0.602 9366 93681 all phecode
519.2 Respiratory complications Respiratory 1.06 0.948 – 1.19 0.302 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.991 0.97 – 1.01 0.433 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.989 0.877 – 1.11 0.852 303 3049 all phecode
520 Disorders of tooth development Digestive 1.01 0.963 – 1.05 0.745 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.914 0.686 – 1.22 0.536 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 0.982 0.942 – 1.02 0.411 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 1 0.966 – 1.04 0.873 3016 30245 all phecode
521.1 Dental caries Digestive 1.01 0.969 – 1.04 0.768 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.03 0.982 – 1.08 0.222 1774 17750 all phecode
522.5 Periapical abscess Digestive 1.03 0.971 – 1.09 0.327 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 1.02 0.967 – 1.07 0.524 1681 16812 all phecode
523.1 Gingivitis Digestive 1.04 0.865 – 1.25 0.678 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.03 0.971 – 1.09 0.315 1165 11650 all phecode
523.31 Acute periodontitis Digestive 1 0.923 – 1.08 0.992 666 6667 all phecode
523.32 Chronic periodontitis Digestive 1.06 0.97 – 1.15 0.208 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.08 0.968 – 1.2 0.167 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.04 0.928 – 1.17 0.492 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.958 0.92 – 0.998 0.0383 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.2 0.955 – 1.5 0.117 72 720 all phecode
526 Diseases of the jaws Digestive 1.01 0.945 – 1.08 0.754 928 9279 all phecode
526.1 Cysts of the jaws Digestive 0.942 0.839 – 1.06 0.312 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.15 0.899 – 1.46 0.27 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.05 0.921 – 1.2 0.469 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.06 0.93 – 1.21 0.373 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.952 0.778 – 1.16 0.63 110 1098 all phecode
526.9 Jaw disease NOS Digestive 1.03 0.897 – 1.18 0.684 233 2329 all phecode
527 Diseases of the salivary glands Digestive 0.982 0.907 – 1.06 0.652 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.12 0.907 – 1.38 0.293 84 838 all phecode
527.2 Sialoadenitis Digestive 0.952 0.854 – 1.06 0.379 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 0.924 0.704 – 1.21 0.569 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 0.955 0.79 – 1.15 0.633 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.996 0.964 – 1.03 0.825 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 1.05 0.955 – 1.15 0.318 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.04 0.94 – 1.15 0.447 389 3884 all phecode
528.12 Oral aphthae Digestive 1.12 0.898 – 1.39 0.317 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.08 0.932 – 1.26 0.298 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 0.947 0.783 – 1.15 0.577 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 0.867 0.693 – 1.08 0.211 94 940 all phecode
528.5 Diseases of lips Digestive 1.02 0.94 – 1.1 0.684 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 0.872 0.771 – 0.985 0.0281 308 3079 all phecode
528.7 Sialolithiasis Digestive 0.98 0.872 – 1.1 0.731 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 1.02 0.967 – 1.09 0.409 1232 12312 all phecode
529.1 Glossitis Digestive 1.11 0.99 – 1.24 0.0743 299 2986 all phecode
530 Diseases of esophagus Digestive 1.01 0.995 – 1.02 0.267 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.01 0.999 – 1.02 0.0753 31253 272429 all phecode
530.11 GERD Digestive 1.01 0.998 – 1.03 0.103 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 1.03 0.997 – 1.05 0.0826 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 1.02 0.999 – 1.04 0.0567 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.949 0.901 – 0.999 0.0454 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.01 0.961 – 1.06 0.741 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 0.995 0.917 – 1.08 0.905 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.978 0.832 – 1.15 0.785 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.984 0.879 – 1.1 0.778 341 3416 all phecode
530.9 Heartburn Digestive 0.994 0.95 – 1.04 0.798 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1 0.98 – 1.03 0.737 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.04 0.958 – 1.12 0.363 637 6374 all phecode
531.2 Gastric ulcer Digestive 0.984 0.953 – 1.02 0.333 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 1.02 0.98 – 1.06 0.376 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 0.929 0.839 – 1.03 0.158 427 4268 all phecode
532 Dysphagia Digestive 0.993 0.968 – 1.02 0.593 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 0.993 0.981 – 1.01 0.257 28078 261548 all phecode
535.1 Acute gastritis Digestive 0.994 0.936 – 1.06 0.844 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 0.993 0.893 – 1.1 0.901 370 3687 all phecode
535.6 Duodenitis Digestive 0.991 0.968 – 1.01 0.447 7592 75928 all phecode
535.8 Other specified gastritis Digestive 0.994 0.972 – 1.02 0.609 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.993 0.823 – 1.2 0.942 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.985 0.869 – 1.12 0.818 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 1.01 0.974 – 1.04 0.63 3391 33907 all phecode
540 Appendiceal conditions Digestive 0.984 0.949 – 1.02 0.404 3088 30890 all phecode
540.1 Appendicitis Digestive 0.979 0.942 – 1.02 0.271 2895 28963 all phecode
540.11 Acute appendicitis Digestive 0.975 0.936 – 1.01 0.21 2601 26019 all phecode
550 Abdominal hernia Digestive 1 0.991 – 1.01 0.883 45429 282640 all phecode
550.1 Inguinal hernia Digestive 0.995 0.979 – 1.01 0.547 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 1 0.992 – 1.02 0.466 26494 238953 all phecode
550.3 Femoral hernia Digestive 1.02 0.938 – 1.1 0.706 651 6504 all phecode
550.4 Umbilical hernia Digestive 1.02 0.987 – 1.06 0.233 3705 37072 all phecode
550.5 Ventral hernia Digestive 1 0.966 – 1.04 0.986 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1 0.973 – 1.03 0.819 4444 44442 all phecode
555.1 Regional enteritis Digestive 1 0.957 – 1.06 0.844 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 0.995 0.959 – 1.03 0.776 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1 0.92 – 1.1 0.916 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 1.06 0.997 – 1.13 0.0638 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 1.01 0.933 – 1.09 0.81 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.01 0.901 – 1.14 0.821 299 2987 all phecode
557.1 Celiac disease Digestive 0.969 0.923 – 1.02 0.204 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 1.01 0.997 – 1.03 0.115 15492 155105 all phecode
559 Ileostomy status Digestive 0.976 0.927 – 1.03 0.356 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.02 0.989 – 1.06 0.185 3936 39337 all phecode
560.1 Paralytic ileus Digestive 1.05 0.96 – 1.15 0.292 523 5231 all phecode
560.2 Impaction of intestine Digestive 1.02 0.905 – 1.16 0.719 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.971 0.904 – 1.04 0.43 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 1.01 0.972 – 1.04 0.675 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 1 0.987 – 1.02 0.704 15772 157686 all phecode
561.1 Diarrhea Digestive 1.03 0.936 – 1.13 0.555 466 4653 all phecode
561.2 Flatulence Digestive 1.02 0.97 – 1.07 0.458 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 0.996 0.984 – 1.01 0.585 26714 211692 all phecode
562.1 Diverticulosis Digestive 0.996 0.984 – 1.01 0.561 26672 211642 all phecode
563 Constipation Digestive 0.997 0.977 – 1.02 0.802 10314 103140 all phecode
564 Functional digestive disorders Digestive 0.995 0.982 – 1.01 0.52 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 1 0.976 – 1.03 0.807 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1 0.953 – 1.06 0.918 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 0.993 0.976 – 1.01 0.385 15186 151648 all phecode
565 Anal and rectal conditions Digestive 0.993 0.977 – 1.01 0.436 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 1 0.977 – 1.02 0.959 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.01 0.945 – 1.08 0.763 929 9293 all phecode
568 Other disorders of peritoneum Digestive 1.03 0.998 – 1.07 0.0666 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.03 0.991 – 1.07 0.136 3101 30987 all phecode
569 Other disorders of intestine Digestive 1.01 0.979 – 1.04 0.524 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.874 0.73 – 1.05 0.143 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 1.07 0.975 – 1.17 0.16 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 1.01 0.972 – 1.05 0.641 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.03 0.981 – 1.08 0.224 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.978 0.806 – 1.19 0.819 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 1.04 0.918 – 1.18 0.526 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.978 0.915 – 1.04 0.502 976 9804 all phecode
571.81 Portal hypertension Digestive 0.953 0.871 – 1.04 0.295 528 5285 all phecode
572 Ascites (non malignant) Digestive 1.04 0.987 – 1.09 0.14 1544 15454 all phecode
573 Other disorders of liver Digestive 1 0.952 – 1.06 0.883 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 0.905 0.725 – 1.13 0.374 96 960 all phecode
573.3 Hepatomegaly Digestive 0.977 0.867 – 1.1 0.702 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 0.955 0.891 – 1.02 0.192 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 1 0.966 – 1.04 0.99 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 0.984 0.856 – 1.13 0.82 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 0.989 0.973 – 1.01 0.21 15607 156123 all phecode
574.1 Cholelithiasis Digestive 0.986 0.969 – 1 0.124 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.959 0.908 – 1.01 0.126 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.01 0.981 – 1.04 0.555 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 1.02 0.979 – 1.06 0.35 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.964 0.926 – 1 0.0684 2748 27523 all phecode
575 Other biliary tract disease Digestive 1 0.969 – 1.04 0.908 3867 38724 all phecode
575.1 Cholangitis Digestive 1.02 0.927 – 1.11 0.735 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 0.959 0.889 – 1.03 0.272 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.977 0.888 – 1.08 0.638 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 1 0.95 – 1.06 0.901 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 1.01 0.948 – 1.08 0.76 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.01 0.905 – 1.12 0.873 348 3488 all phecode
577 Diseases of pancreas Digestive 1.01 0.971 – 1.05 0.622 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 1.01 0.968 – 1.06 0.573 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 0.932 0.849 – 1.02 0.137 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.01 0.907 – 1.12 0.882 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.995 – 1.02 0.183 20626 206278 all phecode
578.1 Hematemesis Digestive 0.971 0.926 – 1.02 0.215 1958 19564 all phecode
578.2 Blood in stool Digestive 0.997 0.958 – 1.04 0.886 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.02 0.999 – 1.04 0.0702 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.996 0.968 – 1.02 0.76 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.02 0.964 – 1.07 0.572 1548 15498 all phecode
579.2 Splenomegaly Digestive 0.995 0.9 – 1.1 0.919 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1 0.95 – 1.05 0.991 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.07 1.02 – 1.13 0.0108 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 1.07 1 – 1.13 0.0439 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.985 0.786 – 1.24 0.896 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.826 0.686 – 0.994 0.043 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.1 1.02 – 1.17 0.00763 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.12 1.03 – 1.23 0.0119 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.01 0.885 – 1.15 0.903 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.02 0.899 – 1.16 0.758 253 2529 all phecode
585 Renal failure Genitourinary 1.03 1.01 – 1.06 0.00962 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 1.03 1 – 1.06 0.0394 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 1.03 0.976 – 1.08 0.288 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.04 1 – 1.08 0.0506 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 1.04 0.949 – 1.14 0.4 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 0.998 0.963 – 1.03 0.895 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.902 0.778 – 1.05 0.173 208 2089 all phecode
586.11 Small kidney Genitourinary 0.932 0.795 – 1.09 0.382 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.02 0.959 – 1.08 0.585 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.06 0.853 – 1.32 0.588 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1 0.936 – 1.07 0.962 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 1.02 0.915 – 1.13 0.734 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.07 0.866 – 1.31 0.548 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.02 0.844 – 1.22 0.865 116 1158 all phecode
590 Pyelonephritis Genitourinary 1.03 0.971 – 1.09 0.356 1328 13285 all phecode
591 Urinary tract infection Genitourinary 0.991 0.972 – 1.01 0.321 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 0.99 0.954 – 1.03 0.613 2966 29661 all phecode
592.1 Cystitis Genitourinary 0.984 0.947 – 1.02 0.401 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 0.978 0.825 – 1.16 0.802 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 0.974 0.908 – 1.04 0.458 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.98 0.86 – 1.12 0.761 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.12 0.961 – 1.3 0.151 165 1662 all phecode
593 Hematuria Genitourinary 0.969 0.953 – 0.985 0.000163 16068 160204 all phecode
594 Urinary calculus Genitourinary 0.957 0.932 – 0.983 0.00104 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 0.96 0.925 – 0.996 0.0314 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 0.883 0.817 – 0.954 0.00158 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 0.974 0.933 – 1.02 0.22 2401 24024 all phecode
594.8 Renal colic Genitourinary 0.972 0.928 – 1.02 0.213 2050 20500 all phecode
595 Hydronephrosis Genitourinary 0.966 0.922 – 1.01 0.157 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 1.01 0.985 – 1.03 0.618 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 0.968 0.924 – 1.01 0.173 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 1 0.951 – 1.05 0.999 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.02 0.988 – 1.05 0.215 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.02 0.98 – 1.05 0.4 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 1.06 0.851 – 1.33 0.583 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 0.982 0.948 – 1.02 0.304 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.999 0.889 – 1.12 0.987 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.99 0.975 – 1 0.181 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 0.89 0.754 – 1.05 0.168 166 1670 all phecode
599.2 Retention of urine Genitourinary 1.03 1 – 1.05 0.0517 6718 67168 all phecode
599.3 Dysuria Genitourinary 0.985 0.928 – 1.05 0.632 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 0.99 0.968 – 1.01 0.365 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1 0.973 – 1.04 0.78 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 0.931 0.757 – 1.14 0.495 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 0.925 0.71 – 1.21 0.562 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 1.03 0.981 – 1.08 0.243 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 1 0.983 – 1.02 0.785 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.995 0.952 – 1.04 0.832 2081 20818 all phecode
601.1 Prostatitis Genitourinary 1.02 0.971 – 1.08 0.403 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 1.02 0.893 – 1.16 0.797 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 1.01 0.945 – 1.08 0.755 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.17 0.907 – 1.52 0.223 59 588 all phecode
601.4 Balanoposthitis Genitourinary 0.931 0.824 – 1.05 0.256 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.988 0.878 – 1.11 0.848 303 3019 all phecode
602 Other disorders of prostate Genitourinary 1.01 0.955 – 1.07 0.724 1341 13408 all phecode
603 Other disorders of testis Genitourinary 0.996 0.952 – 1.04 0.845 2150 21512 all phecode
603.1 Hydrocele Genitourinary 0.981 0.927 – 1.04 0.512 1339 13402 all phecode
604 Disorders of penis Genitourinary 1.01 0.971 – 1.04 0.723 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.98 0.941 – 1.02 0.308 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.08 0.957 – 1.21 0.22 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 1.02 0.981 – 1.06 0.318 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.01 0.876 – 1.16 0.934 214 2138 all phecode
609.1 Infertility, male Genitourinary 1.07 0.832 – 1.38 0.597 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 1.02 0.874 – 1.19 0.816 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 1 0.961 – 1.04 0.953 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 1.01 0.944 – 1.08 0.786 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.1 0.978 – 1.23 0.112 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 0.944 0.836 – 1.07 0.351 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.982 0.929 – 1.04 0.522 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.992 0.917 – 1.07 0.84 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.02 0.969 – 1.07 0.456 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 1.06 0.816 – 1.39 0.646 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 1.02 0.971 – 1.08 0.386 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.993 0.927 – 1.06 0.842 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.987 0.92 – 1.06 0.716 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 1.16 0.924 – 1.45 0.204 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 0.954 0.906 – 1 0.0728 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 0.921 0.852 – 0.997 0.0415 720 7210 all phecode
613.5 Mastodynia Genitourinary 0.743 0.574 – 0.962 0.0242 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 1.02 0.941 – 1.1 0.667 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 1.01 0.9 – 1.13 0.886 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 0.985 0.854 – 1.14 0.834 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.978 0.951 – 1 0.105 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.965 0.926 – 1.01 0.0911 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.979 0.912 – 1.05 0.566 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.02 0.782 – 1.33 0.881 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.943 0.853 – 1.04 0.251 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.04 0.933 – 1.16 0.473 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1.01 0.892 – 1.14 0.898 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.98 0.941 – 1.02 0.333 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.98 0.927 – 1.04 0.494 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.05 0.956 – 1.16 0.29 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.939 0.869 – 1.01 0.105 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.03 0.914 – 1.17 0.613 274 2737 all phecode
615 Endometriosis Genitourinary 0.979 0.947 – 1.01 0.191 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.07 0.958 – 1.2 0.222 304 3037 all phecode
618 Genital prolapse Genitourinary 1.01 0.991 – 1.03 0.31 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1.01 0.983 – 1.03 0.598 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.02 0.99 – 1.05 0.217 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.03 0.94 – 1.13 0.532 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.965 0.89 – 1.05 0.385 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.998 0.976 – 1.02 0.872 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.03 0.957 – 1.11 0.413 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 0.974 0.939 – 1.01 0.151 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.03 0.987 – 1.06 0.2 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.01 0.961 – 1.06 0.7 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.969 0.915 – 1.03 0.27 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 1.08 0.856 – 1.36 0.514 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 0.977 0.918 – 1.04 0.455 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 0.995 0.975 – 1.02 0.632 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.987 0.964 – 1.01 0.269 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.997 0.962 – 1.03 0.858 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.02 0.964 – 1.08 0.496 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 0.958 0.89 – 1.03 0.257 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.954 0.833 – 1.09 0.49 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.982 0.889 – 1.09 0.72 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 0.983 0.956 – 1.01 0.206 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.989 0.952 – 1.03 0.581 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 0.99 0.932 – 1.05 0.744 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1 0.984 – 1.02 0.928 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1 0.986 – 1.02 0.718 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.973 0.795 – 1.19 0.793 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.01 0.985 – 1.03 0.588 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 0.981 0.937 – 1.03 0.432 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 1.01 0.973 – 1.04 0.721 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 0.959 0.912 – 1.01 0.096 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 1.12 0.962 – 1.3 0.145 159 1587 all phecode
626.8 Infertility, female Genitourinary 0.971 0.918 – 1.03 0.304 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.01 0.992 – 1.03 0.231 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 1.01 0.99 – 1.03 0.306 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 1.09 0.946 – 1.26 0.228 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.989 0.93 – 1.05 0.738 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 1.07 0.949 – 1.2 0.283 310 3097 all phecode
628 Ovarian cyst Genitourinary 0.986 0.957 – 1.02 0.372 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.988 0.959 – 1.02 0.413 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.03 0.972 – 1.1 0.293 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.03 0.923 – 1.15 0.585 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.999 0.953 – 1.05 0.964 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1 0.933 – 1.07 0.975 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.997 0.941 – 1.06 0.911 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.02 0.975 – 1.06 0.417 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 1.03 0.947 – 1.12 0.511 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.02 0.958 – 1.08 0.541 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 0.926 0.713 – 1.2 0.566 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.991 0.931 – 1.05 0.78 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.09 0.97 – 1.22 0.151 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.835 0.719 – 0.97 0.0184 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.91 0.768 – 1.08 0.276 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 1 0.946 – 1.06 0.918 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.998 0.955 – 1.04 0.934 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.06 0.844 – 1.33 0.61 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.12 0.992 – 1.26 0.0684 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1 0.828 – 1.21 0.999 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.04 0.897 – 1.21 0.599 193 1922 all phecode
650 Normal delivery Pregnancy Complications 0.994 0.948 – 1.04 0.791 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 1 0.896 – 1.12 0.983 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.987 0.939 – 1.04 0.613 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.991 0.938 – 1.05 0.748 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.28 1.02 – 1.6 0.0317 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.981 0.949 – 1.01 0.244 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.03 0.849 – 1.25 0.772 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.952 0.91 – 0.996 0.0313 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.964 0.88 – 1.06 0.438 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.988 0.959 – 1.02 0.427 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.993 0.953 – 1.04 0.752 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.824 0.688 – 0.987 0.0351 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.99 0.873 – 1.12 0.88 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.972 0.746 – 1.27 0.834 63 624 all phecode
679 Complications of in utero procedures Dermatologic 1.09 0.823 – 1.43 0.559 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 1 0.981 – 1.03 0.715 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.916 0.837 – 1 0.0558 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.04 0.951 – 1.13 0.402 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.01 0.981 – 1.04 0.555 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.01 0.983 – 1.04 0.468 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.01 0.982 – 1.04 0.499 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.06 0.981 – 1.15 0.134 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.13 1.07 – 1.2 5.65e-06 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.01 0.966 – 1.05 0.699 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 0.986 0.906 – 1.07 0.753 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 0.883 0.789 – 0.989 0.0318 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1.05 0.965 – 1.15 0.254 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.996 0.952 – 1.04 0.848 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.09 0.972 – 1.23 0.135 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 1.02 0.836 – 1.24 0.845 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.03 0.99 – 1.07 0.148 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.975 0.948 – 1 0.0658 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.858 0.666 – 1.1 0.235 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.832 0.61 – 1.13 0.244 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 0.891 0.729 – 1.09 0.261 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.938 0.877 – 1 0.0614 986 9854 all phecode
694.1 Vitiligo Dermatologic 0.914 0.691 – 1.21 0.532 60 599 all phecode
694.2 Other dyschromia Dermatologic 0.935 0.867 – 1.01 0.0831 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 0.974 0.803 – 1.18 0.787 117 1170 all phecode
695 Erythematous conditions Dermatologic 0.999 0.957 – 1.04 0.965 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 1.07 0.886 – 1.28 0.495 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 1.03 0.869 – 1.23 0.701 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 1.03 0.792 – 1.35 0.807 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.1 0.875 – 1.39 0.407 73 727 all phecode
695.3 Rosacea Dermatologic 1.09 0.969 – 1.22 0.156 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 0.992 0.894 – 1.1 0.874 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.855 0.706 – 1.04 0.11 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 0.991 0.885 – 1.11 0.871 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 1 0.931 – 1.08 0.948 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 0.876 0.762 – 1.01 0.0628 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 0.744 0.57 – 0.97 0.0291 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 0.997 0.904 – 1.1 0.953 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 0.972 0.93 – 1.02 0.205 2252 22509 all phecode
696.4 Psoriasis Dermatologic 0.972 0.93 – 1.02 0.213 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 0.984 0.936 – 1.04 0.539 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 0.979 0.905 – 1.06 0.589 706 7052 all phecode
697 Sarcoidosis Dermatologic 1.05 0.963 – 1.15 0.264 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 0.991 0.921 – 1.07 0.81 782 7814 all phecode
700 Corns and callosities Dermatologic 0.95 0.841 – 1.07 0.408 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1 0.975 – 1.04 0.779 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 1.08 0.874 – 1.35 0.46 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.02 0.974 – 1.06 0.466 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.09 0.843 – 1.4 0.521 61 610 all phecode
701.4 Keloid scar Dermatologic 0.91 0.787 – 1.05 0.205 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.03 0.933 – 1.13 0.592 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 0.951 0.774 – 1.17 0.629 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1 0.975 – 1.03 0.846 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 0.997 0.957 – 1.04 0.899 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 1.01 0.969 – 1.04 0.755 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 1.04 0.934 – 1.16 0.466 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 1.06 0.993 – 1.13 0.0794 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 1.03 0.998 – 1.06 0.074 5267 52727 all phecode
704.1 Alopecia Dermatologic 0.935 0.774 – 1.13 0.486 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.12 0.909 – 1.39 0.281 76 759 all phecode
705 Disorders of sweat glands Dermatologic 0.978 0.854 – 1.12 0.745 228 2287 all phecode
705.3 Hidradenitis Dermatologic 0.955 0.822 – 1.11 0.542 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 1.12 1.03 – 1.21 0.00652 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 1.03 1.01 – 1.05 0.0065 8317 83195 all phecode
706.1 Acne Dermatologic 1.29 1.04 – 1.62 0.0233 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 1.02 0.999 – 1.04 0.0618 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 1.05 0.999 – 1.09 0.056 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 1.05 0.98 – 1.12 0.167 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 1.01 0.98 – 1.05 0.424 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 1.04 0.953 – 1.14 0.365 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 1 0.861 – 1.17 0.959 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.984 0.767 – 1.26 0.9 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1 0.961 – 1.04 0.998 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.03 0.945 – 1.12 0.536 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 1.01 0.925 – 1.1 0.84 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1 0.864 – 1.16 0.98 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.02 0.921 – 1.13 0.703 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.05 0.949 – 1.16 0.356 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.06 0.948 – 1.18 0.307 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.19 0.96 – 1.48 0.112 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.17 0.997 – 1.38 0.0552 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.14 0.895 – 1.47 0.282 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.01 0.979 – 1.04 0.59 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 1 0.974 – 1.04 0.782 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.973 0.925 – 1.02 0.3 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.968 0.799 – 1.17 0.737 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.01 0.934 – 1.1 0.741 618 6177 all phecode
716 Other arthropathies Musculoskeletal 1.01 0.997 – 1.02 0.14 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1 0.967 – 1.04 0.941 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.01 0.991 – 1.02 0.406 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.01 0.996 – 1.02 0.217 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.01 0.949 – 1.07 0.8 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 1.02 0.991 – 1.06 0.151 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1 0.978 – 1.02 0.933 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.01 0.98 – 1.04 0.558 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.02 0.874 – 1.18 0.836 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.03 0.921 – 1.14 0.647 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 1.03 1.01 – 1.05 0.00533 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.01 0.927 – 1.11 0.751 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.05 1.01 – 1.09 0.0112 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 0.954 0.742 – 1.23 0.715 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.04 1.01 – 1.08 0.00697 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 1.06 0.972 – 1.16 0.178 517 5173 all phecode
723.1 Torticollis Musculoskeletal 1.02 0.841 – 1.24 0.843 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.04 0.992 – 1.08 0.112 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 0.974 0.88 – 1.08 0.619 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 0.967 0.873 – 1.07 0.517 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.15 0.904 – 1.47 0.255 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.05 0.997 – 1.1 0.0641 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.996 0.979 – 1.01 0.644 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 1 0.982 – 1.02 0.815 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 0.947 0.844 – 1.06 0.35 334 3336 all phecode
726.3 Bursitis Musculoskeletal 0.984 0.917 – 1.06 0.646 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.01 0.984 – 1.03 0.543 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.979 0.941 – 1.02 0.29 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 1.02 0.838 – 1.24 0.859 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.02 0.981 – 1.06 0.362 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 1.04 0.957 – 1.13 0.352 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.03 0.921 – 1.14 0.638 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.02 0.858 – 1.21 0.821 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.02 0.987 – 1.06 0.229 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.06 0.963 – 1.17 0.227 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 1.02 0.989 – 1.06 0.191 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.02 0.983 – 1.05 0.311 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.02 0.989 – 1.04 0.247 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.01 0.945 – 1.08 0.796 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 0.917 0.743 – 1.13 0.415 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.972 0.857 – 1.1 0.655 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.968 0.851 – 1.1 0.625 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 0.937 0.85 – 1.03 0.193 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.851 0.732 – 0.99 0.0361 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.09 0.844 – 1.42 0.495 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 1 0.952 – 1.05 0.986 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 0.952 0.845 – 1.07 0.421 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.02 0.929 – 1.11 0.736 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 1.06 0.891 – 1.26 0.518 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.985 0.929 – 1.04 0.617 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 0.804 0.657 – 0.983 0.0337 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 1.01 0.985 – 1.03 0.586 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 1.03 0.89 – 1.19 0.716 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 1.01 0.982 – 1.04 0.458 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.03 0.98 – 1.08 0.261 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 0.99 0.939 – 1.04 0.707 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.01 0.981 – 1.03 0.629 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 1.03 0.975 – 1.08 0.32 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.04 0.914 – 1.18 0.554 248 2476 all phecode
737 Curvature of spine Musculoskeletal 1 0.944 – 1.07 0.918 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.997 0.936 – 1.06 0.932 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.994 0.948 – 1.04 0.791 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.968 0.918 – 1.02 0.24 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 0.957 0.872 – 1.05 0.349 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 1.01 0.998 – 1.02 0.0984 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.01 0.993 – 1.02 0.259 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1 0.982 – 1.03 0.763 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.999 0.895 – 1.11 0.98 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.966 0.887 – 1.05 0.433 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.01 0.993 – 1.03 0.225 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.04 1 – 1.07 0.0396 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 1 0.816 – 1.23 0.982 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 1.06 0.981 – 1.15 0.133 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 1.05 0.899 – 1.23 0.526 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 1.06 1.01 – 1.12 0.0317 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 1.11 0.916 – 1.34 0.29 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 0.866 0.65 – 1.15 0.328 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.03 0.989 – 1.07 0.162 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 1.06 0.949 – 1.19 0.298 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.904 0.73 – 1.12 0.355 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.08 0.987 – 1.19 0.0911 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 1.02 0.978 – 1.07 0.314 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.01 0.987 – 1.03 0.403 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 1.01 0.981 – 1.03 0.628 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 1.01 0.98 – 1.04 0.613 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 0.98 0.896 – 1.07 0.661 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 1.03 0.945 – 1.13 0.471 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.03 0.964 – 1.11 0.348 815 8144 all phecode
745 Pain in joint Musculoskeletal 1 0.979 – 1.03 0.848 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.99 0.952 – 1.03 0.621 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.992 0.952 – 1.03 0.686 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.981 0.899 – 1.07 0.666 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.975 0.85 – 1.12 0.712 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1 0.953 – 1.05 0.977 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.966 0.827 – 1.13 0.663 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.12 0.852 – 1.47 0.416 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.08 0.963 – 1.22 0.181 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 1.02 0.942 – 1.1 0.666 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.03 0.924 – 1.15 0.572 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.939 0.809 – 1.09 0.41 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.02 0.915 – 1.14 0.729 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.994 0.869 – 1.14 0.935 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.986 0.818 – 1.19 0.885 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.951 0.902 – 1 0.0699 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.909 0.838 – 0.986 0.0213 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.937 0.849 – 1.03 0.195 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.898 0.779 – 1.04 0.141 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.995 0.926 – 1.07 0.881 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 1.05 0.955 – 1.16 0.302 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.957 0.855 – 1.07 0.447 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.947 0.844 – 1.06 0.356 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 1.03 0.903 – 1.17 0.679 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 0.992 0.858 – 1.15 0.917 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.812 0.629 – 1.05 0.112 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.14 0.952 – 1.35 0.158 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.09 0.866 – 1.37 0.46 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.945 0.776 – 1.15 0.572 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.01 0.911 – 1.11 0.906 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.06 0.924 – 1.22 0.398 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.857 0.72 – 1.02 0.082 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.807 0.646 – 1.01 0.0595 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1 0.92 – 1.09 0.995 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.943 0.747 – 1.19 0.619 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.02 0.928 – 1.13 0.657 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.15 0.976 – 1.35 0.0957 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.15 0.892 – 1.47 0.289 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.991 0.864 – 1.14 0.895 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.96 0.782 – 1.18 0.696 96 959 all phecode
760 Back pain Symptoms 1.02 0.996 – 1.04 0.125 11126 111353 all phecode
761 Cervicalgia Symptoms 1.01 0.958 – 1.06 0.824 1791 17901 all phecode
764 Sciatica Symptoms 1.01 0.97 – 1.05 0.602 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.07 1 – 1.13 0.0363 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 1.15 1.06 – 1.24 0.000411 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.976 0.91 – 1.05 0.5 870 8687 all phecode
771.1 Swelling of limb Symptoms 1.01 0.984 – 1.04 0.372 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 1.08 0.997 – 1.16 0.0587 659 6581 all phecode
773 Pain in limb Symptoms 1 0.979 – 1.03 0.719 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 0.977 0.837 – 1.14 0.77 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.05 1.01 – 1.1 0.0268 1870 18715 all phecode
782.3 Edema Symptoms 1.04 0.989 – 1.09 0.124 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 1.03 0.88 – 1.2 0.72 175 1748 all phecode
783 Fever of unknown origin Symptoms 1.01 0.977 – 1.04 0.582 3911 39105 all phecode
785 Abdominal pain Symptoms 1 0.992 – 1.01 0.639 40080 301686 all phecode
788 Syncope and collapse Symptoms 0.992 0.971 – 1.01 0.455 9069 90813 all phecode
789 Nausea and vomiting Symptoms 1 0.983 – 1.02 0.864 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.03 0.876 – 1.22 0.708 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 0.871 0.687 – 1.11 0.256 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.02 0.993 – 1.05 0.158 6357 63635 all phecode
791 Gangrene Symptoms 1.08 0.989 – 1.17 0.0865 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.897 0.722 – 1.12 0.329 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.07 0.907 – 1.27 0.412 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.01 0.924 – 1.1 0.886 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.976 0.811 – 1.18 0.799 120 1198 all phecode
797 Shock Symptoms 1.11 0.952 – 1.3 0.18 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 1.1 0.906 – 1.33 0.342 102 1020 all phecode
798 Malaise and fatigue Symptoms 0.999 0.964 – 1.04 0.969 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 0.991 0.91 – 1.08 0.84 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 1.02 0.996 – 1.05 0.0964 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.997 0.95 – 1.05 0.902 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.16 0.998 – 1.34 0.0524 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.05 1.01 – 1.1 0.0224 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 1.06 0.989 – 1.14 0.0974 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.02 0.979 – 1.07 0.324 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.05 0.999 – 1.1 0.0545 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 1.03 0.957 – 1.11 0.404 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 1.02 0.999 – 1.04 0.0598 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.02 0.973 – 1.07 0.379 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.02 0.995 – 1.05 0.112 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.04 0.986 – 1.09 0.152 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 1.01 0.975 – 1.05 0.563 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.01 0.955 – 1.07 0.732 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 0.98 0.91 – 1.05 0.583 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.02 0.963 – 1.08 0.501 1300 12998 all phecode
817 Concussion Injuries & Poisonings 1.05 0.922 – 1.19 0.472 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.07 0.983 – 1.17 0.116 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.02 0.986 – 1.06 0.231 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 1.07 1.02 – 1.12 0.00785 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 0.994 0.95 – 1.04 0.779 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 1.02 0.999 – 1.03 0.0582 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.05 0.963 – 1.15 0.262 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 0.959 0.872 – 1.05 0.387 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.02 0.996 – 1.05 0.0993 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.05 0.89 – 1.24 0.568 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.02 0.928 – 1.11 0.72 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.01 0.965 – 1.06 0.617 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1 0.946 – 1.06 0.922 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.971 0.936 – 1.01 0.117 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.01 0.978 – 1.05 0.439 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1.3 1.04 – 1.63 0.0239 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.02 0.99 – 1.06 0.168 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.954 0.842 – 1.08 0.468 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 1.04 0.896 – 1.2 0.635 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.04 0.998 – 1.08 0.0656 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.04 0.908 – 1.2 0.56 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 0.899 0.702 – 1.15 0.399 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.01 0.978 – 1.04 0.529 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.06 0.807 – 1.39 0.681 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.09 0.878 – 1.35 0.438 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.05 0.905 – 1.22 0.517 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 1.01 0.916 – 1.11 0.891 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 1.12 0.984 – 1.28 0.0845 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.1 0.95 – 1.28 0.197 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.13 0.961 – 1.32 0.143 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.03 0.97 – 1.08 0.375 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.03 0.994 – 1.06 0.11 4260 42663 all phecode
916 Contusion Injuries & Poisonings 1 0.95 – 1.06 0.93 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.896 0.763 – 1.05 0.184 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.03 0.929 – 1.14 0.589 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.934 0.819 – 1.06 0.307 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.03 0.988 – 1.08 0.161 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.11 0.972 – 1.27 0.123 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.01 0.824 – 1.23 0.956 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.949 0.867 – 1.04 0.261 550 5509 all phecode
947 Urticaria Injuries & Poisonings 1.05 0.942 – 1.16 0.4 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 0.925 0.831 – 1.03 0.151 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.966 0.873 – 1.07 0.494 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.996 0.879 – 1.13 0.95 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.03 0.94 – 1.13 0.517 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.04 0.798 – 1.35 0.776 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.885 0.687 – 1.14 0.348 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.01 0.992 – 1.02 0.35 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.01 0.992 – 1.03 0.297 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 0.964 0.87 – 1.07 0.481 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.972 0.906 – 1.04 0.425 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.08 0.971 – 1.2 0.162 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.07 0.967 – 1.2 0.181 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.992 0.864 – 1.14 0.912 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.08 0.963 – 1.21 0.186 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.12 0.993 – 1.25 0.0666 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.987 0.961 – 1.01 0.33 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.01 0.95 – 1.07 0.768 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.07 0.977 – 1.17 0.143 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.943 0.851 – 1.05 0.265 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.02 0.937 – 1.12 0.598 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.06 0.975 – 1.15 0.172 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 0.987 0.941 – 1.03 0.572 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.969 0.835 – 1.13 0.684 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.01 0.894 – 1.15 0.85 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.959 0.77 – 1.19 0.709 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.26 1.05 – 1.52 0.0145 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.13 0.934 – 1.38 0.203 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.856 0.655 – 1.12 0.254 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1 0.762 – 1.32 0.995 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1 0.878 – 1.15 0.969 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 0.976 0.903 – 1.06 0.542 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.931 0.806 – 1.08 0.333 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.01 0.787 – 1.29 0.947 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 0.954 0.779 – 1.17 0.653 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.985 0.809 – 1.2 0.882 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.958 0.767 – 1.2 0.703 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 0.998 0.962 – 1.04 0.925 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.01 0.974 – 1.05 0.579 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 1.01 0.974 – 1.05 0.579 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 1.02 0.996 – 1.05 0.0878 5538 63928 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.03 0.978 – 1.08 0.287 1663 19453 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.06 0.948 – 1.18 0.312 316 4512 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.01 0.926 – 1.11 0.794 514 6251 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.06 0.77 – 1.47 0.704 32 412 exclusion phecode
010 Tuberculosis Infectious Diseases 1.03 0.846 – 1.25 0.77 100 1154 exclusion phecode
038 Septicemia Infectious Diseases 1.04 0.994 – 1.08 0.0895 2126 29197 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.07 0.975 – 1.18 0.15 415 5900 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.08 0.948 – 1.23 0.253 227 3457 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.05 1.02 – 1.07 0.000272 6955 85937 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.11 1.06 – 1.16 1.9e-05 1679 22196 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.03 0.966 – 1.1 0.361 976 11987 exclusion phecode
041.4 E. coli Infectious Diseases 1.06 1.01 – 1.12 0.0252 1520 19569 exclusion phecode
053 Herpes zoster Infectious Diseases 1.02 0.897 – 1.17 0.72 225 2821 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.765 0.573 – 1.02 0.0687 57 644 exclusion phecode
054 Herpes simplex Infectious Diseases 1.01 0.852 – 1.2 0.913 141 1606 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.08 0.965 – 1.2 0.188 323 4477 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.16 0.881 – 1.53 0.291 48 549 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 1.15 0.929 – 1.43 0.199 73 968 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.13 0.95 – 1.33 0.173 132 2012 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 0.943 0.79 – 1.13 0.515 140 2057 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.05 0.925 – 1.2 0.435 224 3107 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.11 0.891 – 1.39 0.347 73 1099 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.11 0.871 – 1.42 0.391 59 878 exclusion phecode
078 Viral warts & HPV Infectious Diseases 0.998 0.924 – 1.08 0.969 706 7578 exclusion phecode
079 Viral infection Infectious Diseases 0.99 0.945 – 1.04 0.685 1923 21181 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.914 0.681 – 1.23 0.552 46 518 exclusion phecode
080 Postoperative infection Infectious Diseases 1.03 0.987 – 1.07 0.192 2675 32311 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.07 1.01 – 1.13 0.0172 1363 17494 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.977 0.718 – 1.33 0.883 45 535 exclusion phecode
1000 Burns Injuries & Poisonings 0.964 0.868 – 1.07 0.499 381 4263 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 1.07 0.996 – 1.14 0.065 822 8739 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.04 1 – 1.08 0.0247 3520 39155 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.03 0.889 – 1.18 0.733 191 2193 exclusion phecode
1005 Other symptoms Injuries & Poisonings 1.02 0.955 – 1.1 0.519 863 10313 exclusion phecode
1006 Crushing injury Injuries & Poisonings 1.05 0.905 – 1.23 0.5 176 1821 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 0.943 0.811 – 1.1 0.448 178 1913 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 0.979 0.907 – 1.06 0.597 707 7313 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 1.02 0.995 – 1.05 0.114 5883 62296 exclusion phecode
1010 Other tests Injuries & Poisonings 1 0.967 – 1.03 0.988 3788 42750 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.01 0.986 – 1.04 0.351 5585 64404 exclusion phecode
1012 Late effect Injuries & Poisonings 1.07 0.854 – 1.34 0.553 76 764 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.08 0.936 – 1.24 0.3 199 2244 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.15 0.88 – 1.5 0.306 53 489 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 0.976 0.937 – 1.02 0.228 2671 31277 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.01 0.992 – 1.03 0.227 10738 116961 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.17 1.01 – 1.37 0.0388 161 1992 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 1.19 1.02 – 1.38 0.0304 157 1957 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.976 0.729 – 1.31 0.873 47 532 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.15 0.926 – 1.43 0.204 77 994 exclusion phecode
112 Candidiasis Infectious Diseases 1.03 0.972 – 1.09 0.335 1280 15203 exclusion phecode
117 Mycoses Infectious Diseases 1.17 1 – 1.38 0.0472 142 1917 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.17 0.951 – 1.43 0.14 85 1129 exclusion phecode
130 Spirochetal infection Infectious Diseases 1.01 0.769 – 1.32 0.955 54 603 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 0.915 0.672 – 1.25 0.571 44 522 exclusion phecode
134 Helminthiases Infectious Diseases 1.03 0.834 – 1.28 0.766 85 996 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.02 0.799 – 1.3 0.879 70 838 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.11 0.93 – 1.32 0.251 124 1464 exclusion phecode
145 Cancer of mouth Neoplasms 0.95 0.861 – 1.05 0.31 440 4516 exclusion phecode
145.2 Cancer of tongue Neoplasms 0.876 0.759 – 1.01 0.0711 217 2145 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 1.11 0.879 – 1.41 0.37 68 791 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 0.9 0.642 – 1.26 0.541 37 369 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.904 0.813 – 1 0.0611 392 4321 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 0.855 0.725 – 1.01 0.0637 170 1800 exclusion phecode
149.4 Cancer of larynx Neoplasms 0.953 0.806 – 1.13 0.573 140 1718 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 0.917 0.67 – 1.26 0.591 40 382 exclusion phecode
150 Cancer of esophagus Neoplasms 0.919 0.832 – 1.01 0.0919 441 4965 exclusion phecode
151 Cancer of stomach Neoplasms 1.04 0.935 – 1.17 0.445 331 3675 exclusion phecode
153 Colorectal cancer Neoplasms 1.01 0.976 – 1.05 0.501 2982 31087 exclusion phecode
153.2 Colon cancer Neoplasms 1.03 0.99 – 1.08 0.134 2015 20964 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.978 0.926 – 1.03 0.411 1419 14778 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.02 0.888 – 1.16 0.826 220 2702 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.08 0.858 – 1.36 0.515 69 1024 exclusion phecode
157 Pancreatic cancer Neoplasms 0.975 0.88 – 1.08 0.621 398 4402 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1 0.926 – 1.08 0.972 686 7382 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.988 0.955 – 1.02 0.498 3553 37731 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.02 0.858 – 1.22 0.815 130 1326 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.904 0.755 – 1.08 0.27 131 1394 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.998 0.832 – 1.2 0.98 122 1346 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 1.15 0.854 – 1.55 0.357 41 409 exclusion phecode
165 Cancer within the respiratory system Neoplasms 0.998 0.949 – 1.05 0.938 1593 18688 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.05 0.995 – 1.11 0.073 1233 14797 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 1.11 0.987 – 1.25 0.0812 295 3027 exclusion phecode
170.1 Bone cancer Neoplasms 1.29 1.05 – 1.6 0.0166 84 899 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1.04 0.91 – 1.2 0.542 225 2294 exclusion phecode
172 Skin cancer Neoplasms 0.986 0.965 – 1.01 0.18 9327 92779 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.958 0.914 – 1.01 0.0806 1928 19087 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.959 0.915 – 1.01 0.0851 1951 19315 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.986 0.962 – 1.01 0.227 7542 74823 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 1.11 1 – 1.22 0.0456 406 4415 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.951 0.792 – 1.14 0.586 128 1321 exclusion phecode
174 Breast cancer Neoplasms 1.01 0.985 – 1.03 0.547 9487 97258 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1.01 0.985 – 1.03 0.576 9353 95789 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1 0.98 – 1.02 0.897 8789 90219 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.07 0.869 – 1.31 0.541 93 905 exclusion phecode
175 Acquired absence of breast Neoplasms 0.984 0.937 – 1.03 0.519 1768 18613 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 0.977 0.929 – 1.03 0.353 1779 18031 exclusion phecode
180.1 Cervical cancer Neoplasms 1.02 0.886 – 1.17 0.789 214 2176 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.96 0.911 – 1.01 0.117 1703 17213 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.977 0.91 – 1.05 0.524 847 9520 exclusion phecode
184 Cancer of other female genital organs Neoplasms 0.974 0.912 – 1.04 0.435 1010 10505 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.959 0.886 – 1.04 0.291 715 7284 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.953 0.88 – 1.03 0.241 693 7046 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.952 0.827 – 1.1 0.492 219 2371 exclusion phecode
185 Cancer of prostate Neoplasms 1.03 0.996 – 1.06 0.08 3690 35865 exclusion phecode
187 Cancer of other male genital organs Neoplasms 1.05 0.939 – 1.18 0.384 304 3153 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.48 1.1 – 2 0.01 40 438 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 1.01 0.878 – 1.17 0.873 199 2112 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.87 0.684 – 1.11 0.258 75 735 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.03 0.986 – 1.08 0.182 2136 27012 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.09 0.994 – 1.2 0.0665 403 7221 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.09 0.989 – 1.2 0.0831 383 6951 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.09 0.772 – 1.55 0.611 31 434 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.01 0.956 – 1.07 0.731 1356 15398 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.998 0.942 – 1.06 0.952 1195 13676 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.973 0.754 – 1.26 0.833 58 938 exclusion phecode
190 Cancer of eye Neoplasms 0.849 0.699 – 1.03 0.0991 122 1233 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.947 0.86 – 1.04 0.266 471 4848 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.987 0.889 – 1.09 0.802 389 3944 exclusion phecode
191.11 Cancer of brain Neoplasms 0.986 0.885 – 1.1 0.796 362 3669 exclusion phecode
193 Thyroid cancer Neoplasms 1.13 0.991 – 1.28 0.0694 234 2652 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 0.891 0.678 – 1.17 0.407 58 701 exclusion phecode
195 Cancer, suspected or other Neoplasms 0.992 0.973 – 1.01 0.423 11114 116438 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 0.99 0.971 – 1.01 0.319 10621 111911 exclusion phecode
197 Chemotherapy Neoplasms 1.01 0.996 – 1.03 0.134 14014 156042 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.01 0.983 – 1.04 0.517 6170 67750 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.01 0.976 – 1.04 0.578 3642 38998 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.99 0.938 – 1.05 0.733 1380 15988 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.01 0.95 – 1.08 0.713 1009 11039 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.03 0.977 – 1.08 0.294 1657 18449 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.987 0.903 – 1.08 0.768 527 6027 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.04 0.984 – 1.1 0.167 1291 14889 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.818 0.67 – 0.998 0.0474 119 1353 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.01 0.945 – 1.09 0.705 841 10306 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.13 0.837 – 1.52 0.426 39 706 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.11 1.02 – 1.21 0.021 480 6747 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.21 1.04 – 1.4 0.0138 162 2584 exclusion phecode
201 Hodgkin's disease Neoplasms 0.99 0.844 – 1.16 0.903 160 1976 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.04 0.987 – 1.1 0.131 1288 15846 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.05 0.991 – 1.12 0.0923 1012 12512 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.24 1.09 – 1.41 0.00129 220 2507 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.1 0.985 – 1.22 0.0911 328 4022 exclusion phecode
204 Leukemia Neoplasms 1.06 0.992 – 1.13 0.086 926 11320 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1.07 0.96 – 1.2 0.215 317 3872 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.08 0.756 – 1.55 0.667 34 413 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.07 0.952 – 1.21 0.248 270 3393 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.09 0.973 – 1.23 0.133 271 3228 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 1.13 0.978 – 1.3 0.097 182 2296 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.14 0.943 – 1.38 0.175 103 1010 exclusion phecode
204.4 Multiple myeloma Neoplasms 0.983 0.871 – 1.11 0.781 287 3744 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1 0.986 – 1.02 0.675 12795 134394 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.969 0.895 – 1.05 0.426 681 7213 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.06 1.02 – 1.09 0.00128 3571 37441 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.988 0.863 – 1.13 0.856 234 2505 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.01 0.88 – 1.15 0.93 244 2393 exclusion phecode
214 Lipoma Neoplasms 1.02 0.994 – 1.06 0.122 4392 45251 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.03 0.992 – 1.06 0.128 3277 33835 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.1 1.02 – 1.18 0.00805 820 8233 exclusion phecode
216 Benign neoplasm of skin Neoplasms 1.01 0.979 – 1.03 0.662 5724 57581 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.03 0.932 – 1.13 0.602 435 4529 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 1.02 0.927 – 1.13 0.656 409 4246 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.988 0.966 – 1.01 0.329 8074 81251 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.986 0.964 – 1.01 0.228 8240 82633 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.934 0.823 – 1.06 0.288 269 2832 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 1.01 0.946 – 1.07 0.838 1120 11458 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.915 0.779 – 1.07 0.277 173 1750 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 1.27 1.05 – 1.55 0.0163 94 1038 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.15 0.954 – 1.39 0.141 100 1152 exclusion phecode
224 Benign neoplasm of eye Neoplasms 1.19 0.965 – 1.48 0.103 78 954 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.36 1 – 1.85 0.0474 37 458 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.922 0.843 – 1.01 0.0712 563 5999 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.939 0.858 – 1.03 0.175 528 5694 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.829 0.592 – 1.16 0.275 43 455 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.889 0.763 – 1.04 0.13 196 2039 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.06 0.971 – 1.15 0.204 548 6287 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.08 0.899 – 1.3 0.409 106 1354 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.1 0.97 – 1.25 0.136 237 2662 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.03 0.889 – 1.19 0.706 204 2262 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.949 0.892 – 1.01 0.0979 1141 11659 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.03 0.979 – 1.08 0.269 1842 18187 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.08 0.979 – 1.19 0.123 414 4535 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.927 0.86 – 1 0.0489 779 8411 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.07 0.959 – 1.19 0.232 357 3598 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.84 0.759 – 0.93 0.000827 451 5090 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.04 0.978 – 1.1 0.22 1162 13999 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.986 0.88 – 1.1 0.804 327 3632 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.06 0.827 – 1.35 0.652 57 715 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.961 0.776 – 1.19 0.717 95 1059 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.06 1.04 – 1.08 8.95e-08 9219 108660 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.05 0.976 – 1.14 0.181 700 8273 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.938 0.713 – 1.23 0.648 60 769 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.06 1.04 – 1.08 2.59e-07 8765 103937 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.921 0.795 – 1.07 0.273 201 2279 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.968 0.821 – 1.14 0.699 153 1716 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.958 0.809 – 1.13 0.621 145 1639 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.04 0.918 – 1.18 0.537 260 3014 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.02 0.998 – 1.04 0.0807 10925 131077 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.981 0.93 – 1.03 0.466 1489 19737 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.846 0.705 – 1.01 0.0717 140 1800 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.03 0.595 – 1.8 0.907 8 556 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.973 0.851 – 1.11 0.687 222 3357 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 0.977 0.746 – 1.28 0.864 51 1141 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.02 0.997 – 1.04 0.0874 9579 118577 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.973 0.752 – 1.26 0.838 61 768 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.16 0.814 – 1.64 0.42 25 1338 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.03 0.937 – 1.14 0.509 397 6711 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.06 0.912 – 1.23 0.441 164 3447 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 0.974 0.88 – 1.08 0.609 400 4888 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 1.03 0.889 – 1.2 0.66 172 1858 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.94 0.819 – 1.08 0.376 228 3014 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.947 0.767 – 1.17 0.615 104 1107 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.961 0.805 – 1.15 0.662 124 2404 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.992 0.914 – 1.08 0.843 596 9087 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 0.932 0.847 – 1.03 0.154 451 6676 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.11 1.01 – 1.21 0.0274 461 6281 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.08 0.985 – 1.19 0.1 417 5639 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.24 0.973 – 1.57 0.082 59 1003 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.04 0.946 – 1.15 0.392 413 4880 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.07 0.891 – 1.28 0.482 122 1392 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.32 1.04 – 1.67 0.0242 61 699 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.95 0.8 – 1.13 0.556 143 1869 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.769 0.559 – 1.06 0.106 47 715 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.14 0.95 – 1.37 0.158 107 1033 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.982 0.878 – 1.1 0.758 337 4714 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.16 0.944 – 1.42 0.16 90 1352 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.06 0.809 – 1.4 0.659 52 805 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.19 0.872 – 1.63 0.271 38 549 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.998 0.858 – 1.16 0.982 185 2651 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.998 0.857 – 1.16 0.976 185 2645 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 1.08 0.932 – 1.25 0.311 204 2141 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.05 0.9 – 1.23 0.526 174 1876 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1.07 0.866 – 1.31 0.544 87 1131 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.08 0.868 – 1.34 0.489 80 1064 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.997 0.766 – 1.3 0.981 55 752 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.916 0.743 – 1.13 0.413 102 1134 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.876 0.725 – 1.06 0.173 117 1414 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.04 0.716 – 1.52 0.823 27 340 exclusion phecode
260.6 Anorexia Endocrine/metabolic 0.968 0.883 – 1.06 0.482 494 5856 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.03 0.957 – 1.12 0.403 692 8706 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.05 0.955 – 1.16 0.312 440 5454 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.05 0.927 – 1.19 0.441 258 3312 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.05 0.764 – 1.44 0.772 36 575 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.927 0.783 – 1.1 0.379 152 1775 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.09 0.93 – 1.28 0.288 158 2372 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.09 0.942 – 1.27 0.238 160 2051 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.14 0.965 – 1.34 0.127 134 1749 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.14 0.945 – 1.39 0.168 94 1263 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 0.941 0.723 – 1.22 0.651 55 764 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 1 0.725 – 1.39 0.978 36 475 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.11 0.92 – 1.35 0.269 109 1184 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.07 0.874 – 1.31 0.514 99 1039 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.01 0.999 – 1.03 0.0697 20417 170572 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.01 0.999 – 1.03 0.0746 20374 170389 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.02 1 – 1.03 0.0486 18889 164486 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.901 0.64 – 1.27 0.549 38 411 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.07 0.866 – 1.32 0.539 84 1154 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.15 0.964 – 1.37 0.12 118 1442 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.09 1.04 – 1.15 0.000544 1596 24798 exclusion phecode
274.1 Gout Endocrine/metabolic 1.08 1.02 – 1.14 0.00537 1237 20817 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.21 0.928 – 1.59 0.158 51 735 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.13 1.02 – 1.25 0.0214 384 4360 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.14 1.02 – 1.26 0.017 356 3988 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.08 1.02 – 1.14 0.0112 1172 14742 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 1.05 0.955 – 1.16 0.302 423 4588 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.15 1 – 1.32 0.0437 200 2573 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.11 1.02 – 1.2 0.0128 610 8470 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.08 0.885 – 1.33 0.439 100 1209 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.04 1.01 – 1.08 0.00894 3665 50343 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.07 1.03 – 1.12 0.00107 2110 28095 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.15 0.972 – 1.37 0.102 121 1585 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.05 0.992 – 1.12 0.0872 1071 12445 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.12 1.01 – 1.25 0.0375 311 6533 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.09 1.02 – 1.17 0.0165 773 10104 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.971 0.884 – 1.07 0.532 470 7952 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.01 0.912 – 1.11 0.91 420 7243 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 0.748 0.548 – 1.02 0.0656 52 746 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.02 0.967 – 1.08 0.463 1409 19646 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.19 1.03 – 1.39 0.0204 151 3022 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 0.91 0.727 – 1.14 0.412 88 971 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.05 0.964 – 1.15 0.253 517 6497 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.992 0.872 – 1.13 0.899 238 2573 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 0.987 0.826 – 1.18 0.888 132 1611 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.16 0.783 – 1.71 0.463 26 367 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.09 1.06 – 1.12 5.2e-11 5600 79880 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.09 1.06 – 1.12 4.28e-11 5501 78655 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 0.972 0.756 – 1.25 0.822 61 686 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.27 0.918 – 1.76 0.149 32 510 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.05 0.893 – 1.24 0.541 144 1853 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.07 0.896 – 1.27 0.465 121 1545 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.12 0.892 – 1.4 0.333 77 1012 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.01 0.86 – 1.18 0.929 164 1594 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.02 0.992 – 1.05 0.147 4717 56023 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.02 0.99 – 1.05 0.192 4497 53665 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.01 0.902 – 1.14 0.833 322 3555 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.06 0.98 – 1.15 0.143 613 8034 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.05 0.971 – 1.14 0.207 593 7703 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.06 0.964 – 1.17 0.23 430 5434 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.16 0.96 – 1.41 0.123 103 1327 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 0.941 0.751 – 1.18 0.596 80 1277 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.39 0.935 – 2.05 0.104 23 369 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 0.965 0.771 – 1.21 0.753 77 1087 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 0.98 0.698 – 1.37 0.906 33 406 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.922 0.677 – 1.26 0.609 42 618 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.04 0.808 – 1.34 0.766 59 972 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.937 0.695 – 1.26 0.666 45 730 exclusion phecode
284 Aplastic anemia Hematopoietic 1.15 1 – 1.31 0.0465 200 3051 exclusion phecode
285 Other anemias Hematopoietic 1.03 1 – 1.05 0.0289 7059 87513 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.952 0.818 – 1.11 0.527 185 2064 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.12 0.996 – 1.26 0.0583 268 4887 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.12 0.987 – 1.27 0.0782 235 2923 exclusion phecode
286 Coagulation defects Hematopoietic 0.968 0.887 – 1.06 0.47 557 6766 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.916 0.812 – 1.03 0.155 317 3459 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.794 0.606 – 1.04 0.0931 74 734 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.943 0.813 – 1.09 0.439 201 2233 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 0.987 0.722 – 1.35 0.934 38 460 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.41 1.03 – 1.93 0.0343 29 569 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.978 0.851 – 1.12 0.752 218 2823 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.09 1.02 – 1.17 0.0125 868 11543 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.03 0.829 – 1.29 0.77 80 916 exclusion phecode
287.2 Allergic purpura Hematopoietic 1.03 0.74 – 1.45 0.844 30 395 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.07 0.999 – 1.15 0.0521 812 10830 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 0.986 0.859 – 1.13 0.845 214 2939 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.08 0.765 – 1.53 0.655 32 507 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.04 0.992 – 1.08 0.109 2279 27246 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.02 0.979 – 1.07 0.299 1930 22983 exclusion phecode
288.11 Neutropenia Hematopoietic 1.02 0.977 – 1.07 0.345 1937 23042 exclusion phecode
288.3 Eosinophilia Hematopoietic 1.41 1.06 – 1.89 0.0194 40 499 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.07 0.977 – 1.17 0.144 474 6221 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.967 0.825 – 1.13 0.676 164 2167 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.05 0.995 – 1.1 0.0784 1575 18736 exclusion phecode
289.5 Diseases of spleen Hematopoietic 0.98 0.871 – 1.1 0.741 291 3627 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.1 0.929 – 1.29 0.278 133 2006 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.26 0.927 – 1.71 0.141 38 649 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.969 0.909 – 1.03 0.336 1010 12458 exclusion phecode
290.1 Dementias Mental Disorders 0.995 0.912 – 1.09 0.91 540 6269 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 1.01 0.891 – 1.15 0.857 252 2750 exclusion phecode
290.16 Vascular dementia Mental Disorders 0.987 0.81 – 1.2 0.894 99 1219 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.909 0.809 – 1.02 0.104 328 4252 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.12 0.837 – 1.5 0.447 42 558 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.975 0.889 – 1.07 0.589 499 6087 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.12 0.915 – 1.38 0.265 95 1045 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.912 0.774 – 1.07 0.268 163 1978 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 0.997 0.878 – 1.13 0.969 255 3192 exclusion phecode
292 Neurological disorders Mental Disorders 1.04 1 – 1.08 0.0353 2712 31905 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.03 0.968 – 1.1 0.323 906 10596 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.937 0.763 – 1.15 0.538 99 1299 exclusion phecode
292.3 Memory loss Mental Disorders 1.02 0.933 – 1.12 0.616 469 4916 exclusion phecode
292.4 Altered mental status Mental Disorders 1.03 0.971 – 1.09 0.351 1211 14671 exclusion phecode
292.6 Hallucinations Mental Disorders 1.16 0.998 – 1.35 0.0533 171 2166 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.03 0.974 – 1.08 0.312 1419 15198 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.963 0.885 – 1.05 0.379 605 6623 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.979 0.892 – 1.07 0.65 493 6382 exclusion phecode
295.1 Schizophrenia Mental Disorders 1 0.897 – 1.12 0.94 326 4364 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.04 0.86 – 1.26 0.685 111 1363 exclusion phecode
295.3 Psychosis Mental Disorders 0.872 0.706 – 1.08 0.204 101 1317 exclusion phecode
296 Mood disorders Mental Disorders 1.05 1.03 – 1.07 3.75e-05 8082 94942 exclusion phecode
296.1 Bipolar Mental Disorders 1.07 0.992 – 1.16 0.0787 632 8089 exclusion phecode
296.2 Depression Mental Disorders 1.05 1.02 – 1.07 6.49e-05 7697 90087 exclusion phecode
296.22 Major depressive disorder Mental Disorders 0.995 0.869 – 1.14 0.941 228 2742 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.948 0.821 – 1.1 0.471 208 2413 exclusion phecode
300 Anxiety disorders Mental Disorders 1.03 0.998 – 1.06 0.068 4624 51851 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.03 0.994 – 1.06 0.108 4282 47836 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 0.971 0.799 – 1.18 0.765 109 1153 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.03 0.939 – 1.13 0.517 474 5403 exclusion phecode
300.13 Phobia Mental Disorders 1.02 0.915 – 1.15 0.676 326 3766 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.833 0.668 – 1.04 0.104 97 1080 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.22 0.894 – 1.66 0.211 37 419 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.11 0.895 – 1.38 0.343 86 965 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.09 0.87 – 1.36 0.46 80 891 exclusion phecode
301 Personality disorders Mental Disorders 1.19 1.03 – 1.36 0.0141 203 2700 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.32 1.06 – 1.66 0.0136 74 1010 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 1.04 0.887 – 1.22 0.627 162 1890 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.03 0.917 – 1.15 0.636 327 3543 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.977 0.856 – 1.12 0.735 252 2625 exclusion phecode
303.4 Somatoform disorder Mental Disorders 1.07 0.855 – 1.33 0.57 82 960 exclusion phecode
304 Adjustment reaction Mental Disorders 0.992 0.857 – 1.15 0.917 202 2288 exclusion phecode
305.2 Eating disorder Mental Disorders 0.945 0.739 – 1.21 0.653 73 763 exclusion phecode
306 Other mental disorder Mental Disorders 1.03 1.01 – 1.04 0.00177 17030 167354 exclusion phecode
306.9 Tension headache Mental Disorders 1.05 0.915 – 1.2 0.498 218 2489 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.973 0.742 – 1.28 0.842 54 593 exclusion phecode
313.3 Autism Mental Disorders 1.19 0.876 – 1.6 0.27 39 409 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.01 0.872 – 1.16 0.913 200 2513 exclusion phecode
315.1 Learning disorder Mental Disorders 0.97 0.776 – 1.21 0.789 83 1248 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.861 0.636 – 1.16 0.33 50 615 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.02 0.989 – 1.06 0.183 3375 39026 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.964 0.68 – 1.37 0.838 31 449 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.01 0.986 – 1.03 0.488 8591 92459 exclusion phecode
317.1 Alcoholism Mental Disorders 0.999 0.973 – 1.03 0.941 6050 64215 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.03 0.937 – 1.13 0.563 450 6050 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.04 1.02 – 1.06 4.54e-05 11090 136722 exclusion phecode
320 Meningitis Neurological 0.983 0.875 – 1.11 0.777 314 3432 exclusion phecode
323 Encephalitis Neurological 1.07 0.94 – 1.22 0.307 242 2561 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 1.21 0.949 – 1.54 0.124 62 590 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.15 1 – 1.33 0.0501 186 2017 exclusion phecode
327 Sleep disorders Neurological 1.11 1.03 – 1.19 0.00534 753 8299 exclusion phecode
327.3 Sleep apnea Neurological 1.04 1 – 1.08 0.0494 2509 31613 exclusion phecode
327.4 Insomnia Neurological 1.11 0.917 – 1.33 0.295 106 1206 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.15 0.942 – 1.41 0.169 89 1012 exclusion phecode
331 Other cerebral degenerations Neurological 1.02 0.947 – 1.11 0.562 688 7941 exclusion phecode
331.1 Hydrocephalus Neurological 0.967 0.862 – 1.09 0.575 320 3620 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.11 0.98 – 1.26 0.0995 245 2859 exclusion phecode
332 Parkinson's disease Neurological 1.07 0.997 – 1.16 0.0598 696 7283 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.1 1.01 – 1.19 0.0311 563 6369 exclusion phecode
333.1 Essential tremor Neurological 1.17 0.978 – 1.39 0.0869 119 1443 exclusion phecode
333.2 Myoclonus Neurological 1.15 0.898 – 1.48 0.263 65 700 exclusion phecode
333.4 Torsion dystonia Neurological 0.91 0.773 – 1.07 0.262 169 1872 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.02 0.964 – 1.09 0.429 1142 12828 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.05 0.82 – 1.35 0.689 65 836 exclusion phecode
334.2 Anterior horn cell disease Neurological 1.16 0.987 – 1.36 0.0727 159 1626 exclusion phecode
335 Multiple sclerosis Neurological 1.02 0.952 – 1.08 0.647 1001 10396 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.07 0.913 – 1.25 0.405 157 1874 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 0.934 0.669 – 1.3 0.687 36 467 exclusion phecode
338 Pain Neurological 1.12 1.02 – 1.23 0.0137 465 5734 exclusion phecode
338.1 Acute pain Neurological 1.11 0.97 – 1.26 0.133 226 2898 exclusion phecode
338.2 Chronic pain Neurological 1.11 0.979 – 1.26 0.104 242 2934 exclusion phecode
339 Other headache syndromes Neurological 1.02 0.989 – 1.04 0.247 5457 59083 exclusion phecode
340 Migraine Neurological 0.997 0.953 – 1.04 0.886 2104 22427 exclusion phecode
340.1 Migrain with aura Neurological 0.95 0.802 – 1.13 0.553 154 1692 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.977 0.84 – 1.14 0.764 196 1993 exclusion phecode
342 Hemiplegia Neurological 1.06 0.99 – 1.14 0.0932 811 10529 exclusion phecode
343 Infantile cerebral palsy Neurological 0.822 0.662 – 1.02 0.0764 101 1092 exclusion phecode
344 Other paralytic syndromes Neurological 1.07 0.975 – 1.18 0.149 415 4841 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.01 0.971 – 1.04 0.76 3449 36984 exclusion phecode
345.1 Epilepsy Neurological 1 0.923 – 1.09 0.92 600 6422 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.07 0.952 – 1.19 0.266 313 3237 exclusion phecode
345.12 Partial epilepsy Neurological 1.03 0.891 – 1.19 0.696 200 2113 exclusion phecode
345.3 Convulsions Neurological 1.01 0.956 – 1.06 0.803 1513 16471 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.09 0.893 – 1.33 0.4 91 1064 exclusion phecode
348 Other conditions of brain Neurological 1.05 0.954 – 1.15 0.334 469 5731 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.02 0.873 – 1.2 0.777 159 2021 exclusion phecode
348.4 Cerebral cysts Neurological 1.11 0.91 – 1.36 0.298 97 1023 exclusion phecode
348.7 Coma Neurological 1 0.88 – 1.14 0.972 244 2540 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.07 0.904 – 1.26 0.452 147 1803 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 0.925 0.814 – 1.05 0.229 266 2780 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.02 0.898 – 1.17 0.716 221 2482 exclusion phecode
350 Abnormal movement Neurological 1.05 1 – 1.11 0.0386 1558 18808 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.03 0.944 – 1.12 0.509 540 6480 exclusion phecode
350.2 Abnormality of gait Neurological 1.05 0.983 – 1.12 0.143 884 10945 exclusion phecode
350.3 Lack of coordination Neurological 1.05 0.92 – 1.2 0.464 223 2634 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.06 0.775 – 1.45 0.718 39 397 exclusion phecode
351 Other peripheral nerve disorders Neurological 0.999 0.977 – 1.02 0.908 8509 92624 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.02 0.956 – 1.09 0.506 903 9985 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 1.01 0.905 – 1.13 0.823 319 3438 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 0.981 0.899 – 1.07 0.659 565 6376 exclusion phecode
353 Nerve root and plexus disorders Neurological 1.01 0.936 – 1.09 0.778 692 8200 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.868 0.681 – 1.11 0.25 79 883 exclusion phecode
353.2 Nerve root lesions Neurological 1.18 0.869 – 1.61 0.286 36 413 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.19 0.976 – 1.46 0.0851 93 1075 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.16 1.08 – 1.24 3.72e-05 759 9463 exclusion phecode
358 Myoneural disorders Neurological 1.07 0.895 – 1.28 0.449 113 1447 exclusion phecode
358.1 Myasthenia gravis Neurological 1.13 0.939 – 1.36 0.195 105 1336 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 1.13 0.998 – 1.28 0.0534 245 3358 exclusion phecode
359.1 Muscular dystrophies Neurological 1.01 0.782 – 1.3 0.956 61 888 exclusion phecode
359.2 Myopathy Neurological 1.18 1.03 – 1.36 0.0167 190 2586 exclusion phecode
360 Disorders of the globe Sense Organs 0.943 0.821 – 1.08 0.411 226 2287 exclusion phecode
360.2 Progressive myopia Sense Organs 0.992 0.847 – 1.16 0.916 167 1721 exclusion phecode
361 Retinal detachments and defects Sense Organs 1.01 0.971 – 1.06 0.553 2307 22703 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 1 0.94 – 1.07 0.92 980 9779 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.845 0.61 – 1.17 0.31 40 490 exclusion phecode
362 Other retinal disorders Sense Organs 1.03 0.989 – 1.07 0.155 2379 25973 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.05 0.991 – 1.1 0.102 1374 14566 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.04 0.99 – 1.1 0.11 1372 14540 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.06 0.876 – 1.28 0.555 106 1132 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1.06 0.848 – 1.33 0.591 76 683 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.08 0.986 – 1.18 0.0993 475 5694 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.912 0.758 – 1.1 0.33 126 1302 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.799 0.602 – 1.06 0.118 61 584 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.893 0.706 – 1.13 0.342 79 801 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.974 0.795 – 1.19 0.798 104 1221 exclusion phecode
363.3 Chorioretinal scars Sense Organs 1.07 0.768 – 1.48 0.702 34 506 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.984 0.892 – 1.08 0.741 440 4556 exclusion phecode
364.1 Corneal opacity Sense Organs 1.11 0.856 – 1.45 0.423 58 650 exclusion phecode
364.2 Corneal edema Sense Organs 0.995 0.726 – 1.36 0.975 43 547 exclusion phecode
364.4 Corneal degenerations Sense Organs 1.11 0.947 – 1.31 0.191 149 1459 exclusion phecode
364.41 Keratoconus Sense Organs 1.07 0.845 – 1.36 0.566 66 667 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.874 0.727 – 1.05 0.153 136 1407 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.882 0.686 – 1.14 0.33 69 706 exclusion phecode
365 Glaucoma Sense Organs 1.01 0.968 – 1.04 0.774 2838 29671 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 1.02 0.943 – 1.1 0.645 674 6777 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 1.02 0.944 – 1.1 0.61 670 6746 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.02 0.928 – 1.12 0.704 477 4805 exclusion phecode
366 Cataract Sense Organs 1.01 0.987 – 1.02 0.562 12277 115766 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.998 0.739 – 1.35 0.991 42 517 exclusion phecode
366.2 Senile cataract Sense Organs 1.01 0.982 – 1.04 0.465 5021 54573 exclusion phecode
366.3 Traumatic cataract Sense Organs 1.19 0.95 – 1.49 0.129 69 681 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.997 0.947 – 1.05 0.901 1610 16847 exclusion phecode
367.1 Myopia Sense Organs 1.02 0.949 – 1.09 0.65 880 8778 exclusion phecode
367.2 Astigmatism Sense Organs 1 0.836 – 1.2 0.97 124 1340 exclusion phecode
367.8 Hypermetropia Sense Organs 1.02 0.873 – 1.2 0.775 162 1737 exclusion phecode
367.9 Blindness and low vision Sense Organs 0.959 0.869 – 1.06 0.411 439 4993 exclusion phecode
368 Visual disturbances Sense Organs 1.05 0.998 – 1.09 0.0602 1896 21389 exclusion phecode
368.1 Amblyopia Sense Organs 0.974 0.869 – 1.09 0.653 320 3683 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.02 0.923 – 1.12 0.749 454 5275 exclusion phecode
368.3 Anisometropia Sense Organs 1.11 0.924 – 1.34 0.258 103 1123 exclusion phecode
368.4 Visual field defects Sense Organs 1.09 0.948 – 1.25 0.232 209 2315 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 1.14 1.03 – 1.25 0.0108 395 4538 exclusion phecode
369 Infection of the eye Sense Organs 1.07 0.964 – 1.2 0.196 353 4013 exclusion phecode
369.2 Eye infection, viral Sense Organs 1 0.791 – 1.27 0.982 72 887 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 1.03 0.86 – 1.22 0.78 131 1554 exclusion phecode
370 Keratitis Sense Organs 0.994 0.857 – 1.15 0.932 190 2088 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.952 0.777 – 1.17 0.632 97 1021 exclusion phecode
371 Inflammation of the eye Sense Organs 1.04 1 – 1.09 0.0511 2192 22200 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.08 0.964 – 1.2 0.19 307 3471 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 1.03 0.985 – 1.08 0.184 1752 17237 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.05 0.96 – 1.14 0.294 529 5408 exclusion phecode
374 Other disorders of eyelids Sense Organs 1.01 0.973 – 1.04 0.741 3803 40161 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.964 0.889 – 1.05 0.381 641 6965 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.99 0.933 – 1.05 0.725 1222 12800 exclusion phecode
375 Disorders of lacrimal system Sense Organs 1.01 0.955 – 1.06 0.802 1523 15626 exclusion phecode
375.2 Epiphora Sense Organs 1 0.923 – 1.08 0.994 636 6274 exclusion phecode
376 Disorders of the orbit Sense Organs 0.88 0.657 – 1.18 0.392 52 610 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.942 0.821 – 1.08 0.396 228 2651 exclusion phecode
377.1 Optic atrophy Sense Organs 0.959 0.685 – 1.34 0.805 34 417 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 1.01 0.814 – 1.25 0.928 87 959 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.958 0.896 – 1.03 0.217 958 10370 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.927 0.854 – 1.01 0.0726 651 6823 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.01 0.84 – 1.21 0.94 125 1501 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.12 0.962 – 1.31 0.143 171 1962 exclusion phecode
379 Other disorders of eye Sense Organs 0.987 0.946 – 1.03 0.538 2311 25287 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 1.01 0.94 – 1.08 0.843 875 9435 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.974 0.916 – 1.04 0.41 1086 12029 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.05 0.795 – 1.4 0.718 49 522 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.06 0.938 – 1.19 0.358 262 2833 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.914 0.744 – 1.12 0.397 102 1236 exclusion phecode
380 Disorders of external ear Sense Organs 0.997 0.906 – 1.1 0.95 448 4445 exclusion phecode
380.1 Otitis externa Sense Organs 1.07 0.955 – 1.19 0.256 342 3761 exclusion phecode
380.4 Impacted cerumen Sense Organs 1.03 0.914 – 1.17 0.591 250 2575 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.993 0.941 – 1.05 0.803 1414 15684 exclusion phecode
381.1 Otitis media Sense Organs 0.982 0.924 – 1.04 0.549 1156 12856 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.972 0.891 – 1.06 0.521 553 6278 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.995 0.837 – 1.18 0.954 135 1457 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 1.13 0.935 – 1.36 0.211 113 1243 exclusion phecode
381.9 Otorrhea Sense Organs 0.946 0.812 – 1.1 0.478 185 2030 exclusion phecode
382 Otalgia Sense Organs 1.08 0.945 – 1.24 0.258 219 2306 exclusion phecode
383 Otosclerosis Sense Organs 1.05 0.917 – 1.19 0.496 232 2353 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 0.982 0.917 – 1.05 0.605 919 9595 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 0.986 0.913 – 1.06 0.711 732 7653 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.04 0.954 – 1.14 0.364 527 5736 exclusion phecode
385.3 Cholesteatoma Sense Organs 1.02 0.919 – 1.13 0.731 400 4423 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.08 0.93 – 1.26 0.311 170 1806 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.08 1.02 – 1.14 0.0125 1156 12518 exclusion phecode
386.1 Meniere's disease Sense Organs 1.18 1.06 – 1.3 0.0015 369 4126 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 1.05 0.923 – 1.19 0.465 250 2655 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.03 0.945 – 1.13 0.478 515 5560 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.04 1 – 1.08 0.0416 2850 32587 exclusion phecode
388 Other disorders of ear Sense Organs 1.12 0.947 – 1.32 0.186 141 1463 exclusion phecode
389 Hearing loss Sense Organs 1.01 0.975 – 1.06 0.481 2628 29264 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.99 0.879 – 1.12 0.87 296 3179 exclusion phecode
389.2 Conductive hearing loss Sense Organs 0.981 0.87 – 1.11 0.749 296 3354 exclusion phecode
389.4 Tinnitus Sense Organs 0.951 0.849 – 1.07 0.392 336 3644 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.06 1.02 – 1.1 0.00628 2638 32790 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.07 1.02 – 1.12 0.00839 1639 20116 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.07 0.987 – 1.15 0.102 661 8535 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.07 0.982 – 1.16 0.125 555 7030 exclusion phecode
395 Heart valve disorders Circulatory System 1.07 1.03 – 1.11 0.00163 2254 28234 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.07 1.02 – 1.13 0.00409 1586 19409 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.13 0.948 – 1.35 0.174 132 1822 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.04 0.799 – 1.35 0.783 57 709 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.978 0.746 – 1.28 0.871 51 657 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.06 0.983 – 1.14 0.136 743 9813 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.03 0.956 – 1.12 0.414 700 7655 exclusion phecode
401 Hypertension Circulatory System 1.04 1.03 – 1.05 1.25e-11 43185 207901 exclusion phecode
401.1 Essential hypertension Circulatory System 1.04 1.03 – 1.05 1.03e-11 43131 207712 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.08 0.978 – 1.2 0.125 349 13252 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.05 0.9 – 1.22 0.544 157 2564 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.11 0.975 – 1.27 0.112 192 10832 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.19 0.85 – 1.68 0.308 29 1048 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.05 0.982 – 1.12 0.15 908 10889 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.02 1 – 1.04 0.0128 17437 150784 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.03 0.993 – 1.07 0.113 2818 35061 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.02 0.998 – 1.05 0.0731 6320 76419 exclusion phecode
411.3 Angina pectoris Circulatory System 1 0.979 – 1.02 0.943 8723 98965 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.02 1 – 1.04 0.0497 11218 107549 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1.01 0.913 – 1.11 0.894 424 4851 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.02 0.995 – 1.04 0.12 7773 89870 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.993 0.921 – 1.07 0.857 695 8291 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 0.998 0.933 – 1.07 0.951 879 12319 exclusion phecode
414.2 ASCVD Circulatory System 1.23 0.906 – 1.67 0.184 38 477 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.04 0.999 – 1.08 0.0547 2401 31183 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.941 0.702 – 1.26 0.686 44 513 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.11 0.984 – 1.26 0.0885 266 4029 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.06 0.921 – 1.23 0.406 197 3027 exclusion phecode
416 Cardiomegaly Circulatory System 1.03 0.976 – 1.09 0.282 1300 17990 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.03 1.01 – 1.04 0.000483 18523 198416 exclusion phecode
418.1 Precordial pain Circulatory System 1.04 0.996 – 1.08 0.0786 2284 25880 exclusion phecode
420 Carditis Circulatory System 1.07 1.01 – 1.13 0.0215 1212 14499 exclusion phecode
420.1 Myocarditis Circulatory System 1.01 0.804 – 1.28 0.905 74 906 exclusion phecode
420.2 Pericarditis Circulatory System 1.11 1.04 – 1.19 0.00329 783 9266 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.03 0.88 – 1.22 0.682 152 1553 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.08 0.844 – 1.38 0.544 62 736 exclusion phecode
420.3 Endocarditis Circulatory System 0.996 0.9 – 1.1 0.938 400 4851 exclusion phecode
425 Cardiomyopathy Circulatory System 1.04 0.963 – 1.13 0.302 608 8768 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.03 0.949 – 1.12 0.488 596 8515 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.03 0.813 – 1.3 0.809 68 931 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.03 0.831 – 1.27 0.805 89 1171 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.41 1.01 – 1.98 0.0439 28 403 exclusion phecode
426 Cardiac conduction disorders Circulatory System 0.988 0.956 – 1.02 0.458 3814 46144 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 0.972 0.915 – 1.03 0.357 1125 13826 exclusion phecode
426.21 First degree AV block Circulatory System 0.976 0.894 – 1.07 0.588 527 6397 exclusion phecode
426.23 Second degree AV block Circulatory System 1.01 0.893 – 1.14 0.885 268 2957 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 0.971 0.863 – 1.09 0.618 289 3853 exclusion phecode
426.25 Other heart block Circulatory System 1.12 0.897 – 1.41 0.308 75 868 exclusion phecode
426.3 Bundle branch block Circulatory System 1.01 0.963 – 1.06 0.721 1850 22379 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.02 0.953 – 1.09 0.559 840 10047 exclusion phecode
426.32 Left bundle branch block Circulatory System 0.994 0.931 – 1.06 0.853 947 11678 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.955 0.813 – 1.12 0.579 163 1747 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.29 0.95 – 1.75 0.103 38 404 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.988 0.933 – 1.05 0.669 1258 16287 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.977 0.921 – 1.04 0.45 1155 14951 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1 0.987 – 1.02 0.607 14168 146668 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1 0.958 – 1.05 0.912 1998 22708 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.999 0.948 – 1.05 0.964 1538 16947 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.98 0.895 – 1.07 0.657 501 6314 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.01 0.985 – 1.03 0.524 7861 90141 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.99 0.945 – 1.04 0.664 1921 22082 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 1 0.922 – 1.09 0.986 591 8043 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.977 0.845 – 1.13 0.75 190 2342 exclusion phecode
427.42 Cardiac arrest Circulatory System 1.02 0.928 – 1.11 0.727 476 6663 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.03 0.944 – 1.12 0.534 554 6551 exclusion phecode
427.6 Premature beats Circulatory System 1.06 0.947 – 1.18 0.328 333 3786 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 0.825 0.645 – 1.05 0.124 73 831 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.01 0.95 – 1.06 0.857 1309 15806 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.07 0.942 – 1.21 0.309 247 2726 exclusion phecode
427.9 Palpitations Circulatory System 1 0.965 – 1.05 0.838 2672 28419 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.09 1.05 – 1.13 3.06e-05 2359 36584 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.1 1.03 – 1.18 0.00798 713 13567 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.08 1.03 – 1.13 0.000821 1894 29081 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.06 0.961 – 1.16 0.261 462 5073 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 0.786 0.488 – 1.27 0.322 19 447 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.998 0.892 – 1.12 0.978 336 3689 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.24 1.05 – 1.46 0.011 126 1424 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.05 0.99 – 1.11 0.107 1172 13327 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.1 1.01 – 1.19 0.0348 569 6142 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 0.983 0.893 – 1.08 0.731 439 5232 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.04 0.888 – 1.22 0.625 150 1749 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.01 0.979 – 1.04 0.611 4755 58932 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.03 0.949 – 1.11 0.495 603 7600 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.13 0.948 – 1.35 0.171 123 1453 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.998 0.957 – 1.04 0.944 2213 28187 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.974 0.909 – 1.04 0.447 850 11261 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.03 0.977 – 1.08 0.294 1585 19448 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.03 0.972 – 1.09 0.313 1181 14450 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.05 0.922 – 1.19 0.476 260 2923 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.05 0.967 – 1.13 0.261 632 8793 exclusion phecode
440 Atherosclerosis Circulatory System 1 0.926 – 1.09 0.91 602 8853 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.33 0.927 – 1.9 0.122 23 734 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.998 0.9 – 1.11 0.974 365 5154 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1 0.844 – 1.19 0.984 137 1851 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 0.963 0.859 – 1.08 0.515 315 4192 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.885 0.741 – 1.06 0.174 140 1944 exclusion phecode
442 Other aneurysm Circulatory System 1.05 0.987 – 1.13 0.117 871 12071 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.03 0.948 – 1.11 0.514 611 9043 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.04 0.929 – 1.16 0.523 317 5469 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.41 1.03 – 1.91 0.0295 33 605 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.06 0.858 – 1.3 0.601 87 1106 exclusion phecode
442.4 Arterial dissection Circulatory System 1.46 1.1 – 1.92 0.00788 40 411 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.08 0.904 – 1.28 0.411 121 1440 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.02 0.977 – 1.07 0.348 1934 26801 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.06 0.983 – 1.14 0.133 753 8551 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.12 0.938 – 1.34 0.209 111 2583 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.02 0.97 – 1.06 0.501 1857 25181 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.992 0.935 – 1.05 0.781 1122 16871 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.01 0.92 – 1.12 0.79 423 6204 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.03 0.902 – 1.17 0.702 236 3651 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.12 1.02 – 1.24 0.0191 395 5738 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 1.19 0.975 – 1.45 0.0868 81 1295 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.15 1.01 – 1.32 0.0396 206 2622 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.11 0.923 – 1.34 0.262 106 1715 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 0.968 0.893 – 1.05 0.439 621 8868 exclusion phecode
447.1 Stricture of artery Circulatory System 0.99 0.895 – 1.09 0.838 397 5654 exclusion phecode
448 Disease of capillaries Circulatory System 1.05 0.849 – 1.3 0.652 86 1027 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.04 0.939 – 1.15 0.443 381 5156 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.04 0.998 – 1.09 0.0618 2252 27957 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.06 1.01 – 1.1 0.0162 2088 25960 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 0.964 0.856 – 1.09 0.544 305 4118 exclusion phecode
454 Varicose veins Circulatory System 1.02 0.995 – 1.04 0.131 8006 83774 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1.02 0.994 – 1.04 0.14 8287 85950 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.926 0.828 – 1.04 0.184 338 4442 exclusion phecode
455 Hemorrhoids Circulatory System 1.01 0.997 – 1.03 0.109 16487 171594 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.09 0.885 – 1.34 0.418 85 1265 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.05 0.826 – 1.35 0.67 69 663 exclusion phecode
458 Hypotension Circulatory System 1.03 0.995 – 1.07 0.0894 3122 40224 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.01 0.939 – 1.1 0.724 676 8957 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.07 0.892 – 1.29 0.459 118 1585 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.03 0.981 – 1.08 0.25 1883 24554 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.02 0.998 – 1.04 0.0752 8927 112673 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 0.928 0.733 – 1.17 0.533 74 993 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.02 1 – 1.04 0.0513 8849 111669 exclusion phecode
464 Acute sinusitis Respiratory 1.07 0.895 – 1.27 0.472 131 1476 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.999 0.948 – 1.05 0.962 1510 16828 exclusion phecode
465.2 Acute pharyngitis Respiratory 1.05 0.965 – 1.15 0.251 553 6196 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 1 0.833 – 1.21 0.963 110 1204 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.04 1 – 1.07 0.0482 3440 34890 exclusion phecode
471 Nasal polyps Respiratory 1.03 0.984 – 1.07 0.233 2359 23487 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.06 0.978 – 1.14 0.163 694 7120 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.02 0.969 – 1.07 0.49 1688 18166 exclusion phecode
473.1 Chronic laryngitis Respiratory 0.92 0.712 – 1.19 0.522 64 747 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.04 0.895 – 1.21 0.593 172 1889 exclusion phecode
473.4 Voice disturbance Respiratory 0.989 0.915 – 1.07 0.777 706 7600 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1.03 0.972 – 1.09 0.338 1361 14138 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.11 1 – 1.22 0.0425 426 4455 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.992 0.925 – 1.06 0.826 868 8975 exclusion phecode
475 Chronic sinusitis Respiratory 1 0.955 – 1.05 0.96 1842 19122 exclusion phecode
476 Allergic rhinitis Respiratory 0.96 0.891 – 1.03 0.28 804 7930 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.01 0.962 – 1.07 0.602 1468 16711 exclusion phecode
478 Throat pain Respiratory 1.13 1.01 – 1.28 0.0367 269 2775 exclusion phecode
479 Other upper respiratory disease Respiratory 1.03 0.996 – 1.07 0.0814 2863 29922 exclusion phecode
480 Pneumonia Respiratory 1.03 1.01 – 1.06 0.0181 5640 71497 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.04 1.01 – 1.08 0.0164 3627 46061 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.05 1.01 – 1.08 0.012 3210 40833 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.07 0.806 – 1.42 0.633 46 634 exclusion phecode
480.2 Viral pneumonia Respiratory 0.833 0.596 – 1.16 0.285 39 522 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.27 0.96 – 1.69 0.0936 42 678 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.988 0.895 – 1.09 0.809 423 5257 exclusion phecode
481 Influenza Respiratory 1.04 0.901 – 1.2 0.585 191 2422 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.02 0.844 – 1.24 0.827 116 1405 exclusion phecode
495 Asthma Respiratory 1.02 1 – 1.03 0.0284 17338 187928 exclusion phecode
495.2 Asthma with exacerbation Respiratory 0.946 0.805 – 1.11 0.506 164 1912 exclusion phecode
496 Chronic airway obstruction Respiratory 1.04 1.02 – 1.07 0.00224 5308 69214 exclusion phecode
496.1 Emphysema Respiratory 1.05 0.983 – 1.13 0.141 851 11564 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.05 0.995 – 1.11 0.0777 1317 19655 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.05 0.99 – 1.11 0.109 1184 17996 exclusion phecode
496.3 Bronchiectasis Respiratory 0.999 0.941 – 1.06 0.973 1112 13006 exclusion phecode
497 Bronchitis Respiratory 1 0.897 – 1.12 0.952 345 4518 exclusion phecode
500 Lung disease due to external agents Respiratory 1.02 0.886 – 1.17 0.784 190 2563 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.05 0.761 – 1.44 0.778 37 557 exclusion phecode
500.2 Pneumoconiosis Respiratory 0.979 0.81 – 1.18 0.829 105 1418 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.01 0.906 – 1.14 0.803 319 4401 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.09 0.989 – 1.2 0.0829 411 6032 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 0.922 0.795 – 1.07 0.28 188 3519 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.23 1.05 – 1.45 0.00891 142 2260 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.19 0.856 – 1.67 0.295 34 435 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.05 0.967 – 1.13 0.26 651 8026 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.01 0.981 – 1.05 0.409 3569 43880 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.989 0.931 – 1.05 0.721 1123 13891 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.06 1 – 1.12 0.0487 1185 17527 exclusion phecode
509.1 Respiratory failure Respiratory 1.09 1.02 – 1.16 0.00681 923 13859 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.1 1.02 – 1.17 0.00919 807 12198 exclusion phecode
509.5 Respiratory arrest Respiratory 1.1 0.88 – 1.37 0.404 74 1008 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.929 0.799 – 1.08 0.34 184 2579 exclusion phecode
510 Other diseases of lung Respiratory 1.13 1.03 – 1.24 0.0105 432 5174 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.06 1.03 – 1.09 9.76e-06 5300 64335 exclusion phecode
512.1 Wheezing Respiratory 1.03 0.857 – 1.23 0.763 126 1550 exclusion phecode
512.2 Painful respiration Respiratory 1.14 0.96 – 1.35 0.137 140 1523 exclusion phecode
512.7 Shortness of breath Respiratory 1.05 1.02 – 1.09 0.00247 3323 41531 exclusion phecode
512.8 Cough Respiratory 1.08 1.03 – 1.13 0.00153 1711 20522 exclusion phecode
512.9 Other dyspnea Respiratory 1.06 0.977 – 1.16 0.152 532 6453 exclusion phecode
513 Respiratory abnormalities Respiratory 1 0.898 – 1.12 0.963 344 4276 exclusion phecode
513.3 Hypoventilation Respiratory 1.23 0.877 – 1.73 0.229 31 572 exclusion phecode
513.4 Hyperventilation Respiratory 0.933 0.792 – 1.1 0.403 173 2037 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.1 0.895 – 1.35 0.369 94 1002 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.08 1.02 – 1.14 0.00616 1360 16815 exclusion phecode
516 Abnormal sputum Respiratory 1.04 0.977 – 1.1 0.239 1221 14739 exclusion phecode
516.1 Hemoptysis Respiratory 1.03 0.976 – 1.1 0.249 1196 14347 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.03 0.998 – 1.05 0.0661 5349 66112 exclusion phecode
519.2 Respiratory complications Respiratory 1.13 0.964 – 1.33 0.131 149 2197 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.02 0.994 – 1.05 0.125 5049 62577 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.03 0.892 – 1.18 0.721 216 2189 exclusion phecode
520 Disorders of tooth development Digestive 1.03 0.974 – 1.08 0.337 1587 16220 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.953 0.671 – 1.36 0.791 33 402 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.997 0.951 – 1.05 0.913 1872 18920 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.03 0.979 – 1.07 0.287 1978 22781 exclusion phecode
521.1 Dental caries Digestive 1.03 0.98 – 1.07 0.28 1980 22849 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.04 0.987 – 1.1 0.133 1276 13546 exclusion phecode
522.5 Periapical abscess Digestive 1.06 0.988 – 1.14 0.106 834 8939 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.05 0.994 – 1.12 0.0806 1208 12891 exclusion phecode
523.1 Gingivitis Digestive 1.07 0.857 – 1.34 0.546 73 795 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.06 0.992 – 1.14 0.0821 859 9141 exclusion phecode
523.31 Acute periodontitis Digestive 1.05 0.956 – 1.15 0.32 499 5333 exclusion phecode
523.32 Chronic periodontitis Digestive 1.09 0.991 – 1.21 0.0759 405 4296 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.1 0.974 – 1.25 0.121 250 2629 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.07 0.938 – 1.22 0.309 230 2442 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.972 0.925 – 1.02 0.252 1776 19685 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.3 1 – 1.68 0.0497 55 521 exclusion phecode
526 Diseases of the jaws Digestive 1.03 0.949 – 1.11 0.492 657 7001 exclusion phecode
526.1 Cysts of the jaws Digestive 0.934 0.815 – 1.07 0.329 234 2404 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.14 0.869 – 1.49 0.348 49 473 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.11 0.948 – 1.29 0.198 168 1904 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.11 0.953 – 1.3 0.174 164 1846 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 1.06 0.836 – 1.34 0.635 75 816 exclusion phecode
526.9 Jaw disease NOS Digestive 1.01 0.856 – 1.2 0.891 158 1726 exclusion phecode
527 Diseases of the salivary glands Digestive 1.01 0.914 – 1.11 0.909 455 5107 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.15 0.893 – 1.49 0.272 54 601 exclusion phecode
527.2 Sialoadenitis Digestive 0.976 0.855 – 1.11 0.716 240 2739 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 0.885 0.639 – 1.23 0.464 42 460 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 0.91 0.724 – 1.14 0.419 84 875 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.991 0.952 – 1.03 0.644 2634 28527 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.09 0.969 – 1.22 0.157 301 3440 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.07 0.941 – 1.21 0.315 248 2842 exclusion phecode
528.12 Oral aphthae Digestive 1.21 0.926 – 1.58 0.163 56 628 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.07 0.887 – 1.29 0.485 114 1341 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.929 0.743 – 1.16 0.52 90 909 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.922 0.71 – 1.2 0.545 65 703 exclusion phecode
528.5 Diseases of lips Digestive 1.01 0.916 – 1.11 0.882 474 5001 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 0.817 0.699 – 0.956 0.0114 194 2174 exclusion phecode
528.7 Sialolithiasis Digestive 0.958 0.833 – 1.1 0.55 219 2313 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.04 0.973 – 1.12 0.227 829 9018 exclusion phecode
529.1 Glossitis Digestive 1.18 1.02 – 1.35 0.0236 186 2166 exclusion phecode
530 Diseases of esophagus Digestive 1.03 1.01 – 1.04 0.00022 21728 206908 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.03 1.02 – 1.04 5.01e-05 20403 201209 exclusion phecode
530.11 GERD Digestive 1.03 1.01 – 1.05 0.000807 14956 164974 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.05 1.01 – 1.09 0.00656 3155 35906 exclusion phecode
530.14 Reflux esophagitis Digestive 1.04 1.01 – 1.06 0.00219 6827 75648 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1 0.94 – 1.07 0.891 943 11936 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1.01 0.956 – 1.08 0.647 1178 12933 exclusion phecode
530.5 Disorders of esophageal motility Digestive 1.01 0.911 – 1.11 0.886 399 4577 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.05 0.871 – 1.28 0.584 101 1024 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.981 0.853 – 1.13 0.794 215 2522 exclusion phecode
530.9 Heartburn Digestive 0.989 0.938 – 1.04 0.698 1495 15580 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.01 0.981 – 1.04 0.461 4226 49668 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.05 0.941 – 1.16 0.404 352 4319 exclusion phecode
531.2 Gastric ulcer Digestive 0.994 0.954 – 1.04 0.771 2423 28820 exclusion phecode
531.3 Duodenal ulcer Digestive 1.03 0.979 – 1.08 0.278 1799 20881 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 0.941 0.823 – 1.07 0.368 239 2939 exclusion phecode
532 Dysphagia Digestive 1.01 0.982 – 1.04 0.429 4228 46637 exclusion phecode
535 Gastritis and duodenitis Digestive 1.01 0.992 – 1.02 0.376 18173 191285 exclusion phecode
535.1 Acute gastritis Digestive 1.01 0.935 – 1.09 0.838 717 8385 exclusion phecode
535.2 Atrophic gastritis Digestive 1.02 0.897 – 1.17 0.737 234 2533 exclusion phecode
535.6 Duodenitis Digestive 1.01 0.98 – 1.04 0.535 4682 54128 exclusion phecode
535.8 Other specified gastritis Digestive 1.01 0.98 – 1.04 0.578 5239 57860 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.05 0.845 – 1.3 0.668 83 858 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.06 0.917 – 1.23 0.413 175 1868 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.05 1 – 1.1 0.033 2045 24138 exclusion phecode
540 Appendiceal conditions Digestive 0.985 0.943 – 1.03 0.48 2266 23459 exclusion phecode
540.1 Appendicitis Digestive 0.979 0.936 – 1.02 0.337 2134 21972 exclusion phecode
540.11 Acute appendicitis Digestive 0.971 0.927 – 1.02 0.212 1944 19778 exclusion phecode
550 Abdominal hernia Digestive 1.02 1 – 1.03 0.0092 29510 211276 exclusion phecode
550.1 Inguinal hernia Digestive 0.998 0.978 – 1.02 0.843 10584 84628 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.03 1.01 – 1.04 0.000577 16946 174899 exclusion phecode
550.3 Femoral hernia Digestive 0.971 0.885 – 1.07 0.534 492 4835 exclusion phecode
550.4 Umbilical hernia Digestive 1.07 1.03 – 1.12 0.0012 2206 26237 exclusion phecode
550.5 Ventral hernia Digestive 1.01 0.97 – 1.06 0.519 2061 24752 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.02 0.982 – 1.06 0.309 2931 33097 exclusion phecode
555.1 Regional enteritis Digestive 1.01 0.949 – 1.07 0.778 1107 13156 exclusion phecode
555.2 Ulcerative colitis Digestive 1.01 0.971 – 1.06 0.516 2119 23491 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.03 0.924 – 1.14 0.64 381 4097 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.08 1 – 1.16 0.0462 693 7778 exclusion phecode
556.1 Ulceration of intestine Digestive 1.03 0.933 – 1.13 0.581 429 4916 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.03 0.889 – 1.19 0.708 198 2289 exclusion phecode
557.1 Celiac disease Digestive 0.992 0.937 – 1.05 0.784 1289 13848 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.03 1.01 – 1.05 0.00837 10139 116051 exclusion phecode
559 Ileostomy status Digestive 0.977 0.916 – 1.04 0.488 998 11716 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.03 0.994 – 1.08 0.0958 2534 28294 exclusion phecode
560.1 Paralytic ileus Digestive 1.05 0.936 – 1.17 0.418 318 3637 exclusion phecode
560.2 Impaction of intestine Digestive 1.12 0.966 – 1.3 0.133 165 1951 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.95 0.869 – 1.04 0.26 547 6023 exclusion phecode
560.4 Other intestinal obstruction Digestive 1.01 0.97 – 1.06 0.541 2181 24215 exclusion phecode
561 Symptoms involving digestive system Digestive 1.01 0.99 – 1.03 0.326 11071 118093 exclusion phecode
561.1 Diarrhea Digestive 0.98 0.871 – 1.1 0.732 307 3348 exclusion phecode
561.2 Flatulence Digestive 1.01 0.956 – 1.08 0.63 1188 12682 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1.01 0.997 – 1.03 0.109 17018 154122 exclusion phecode
562.1 Diverticulosis Digestive 1.01 0.997 – 1.03 0.124 16988 154070 exclusion phecode
563 Constipation Digestive 1.01 0.987 – 1.04 0.36 6720 75745 exclusion phecode
564 Functional digestive disorders Digestive 1.01 0.996 – 1.03 0.133 14222 154657 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.03 0.996 – 1.06 0.0841 4007 42741 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.01 0.951 – 1.08 0.68 1036 11923 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.01 0.988 – 1.03 0.401 9638 108537 exclusion phecode
565 Anal and rectal conditions Digestive 0.993 0.973 – 1.01 0.496 10014 106323 exclusion phecode
565.1 Anal and rectal polyp Digestive 0.995 0.967 – 1.02 0.761 4897 51529 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.05 0.961 – 1.14 0.285 519 6610 exclusion phecode
568 Other disorders of peritoneum Digestive 1.05 1.01 – 1.1 0.0237 2143 24137 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.05 1 – 1.1 0.0316 2045 22970 exclusion phecode
569 Other disorders of intestine Digestive 1.03 0.988 – 1.07 0.171 2686 29901 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.946 0.762 – 1.17 0.613 94 1003 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.07 0.959 – 1.2 0.222 318 3425 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.09 1.03 – 1.14 0.00111 1504 21458 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.08 1.01 – 1.15 0.0167 944 12403 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.08 0.836 – 1.4 0.55 55 810 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.2 1 – 1.44 0.0492 105 1910 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.08 0.985 – 1.19 0.102 430 6942 exclusion phecode
571.81 Portal hypertension Digestive 1.14 0.999 – 1.3 0.0523 214 3717 exclusion phecode
572 Ascites (non malignant) Digestive 1.07 1 – 1.15 0.0453 870 11009 exclusion phecode
573 Other disorders of liver Digestive 1.05 0.978 – 1.12 0.184 842 10720 exclusion phecode
573.2 Liver replaced by transplant Digestive 0.933 0.569 – 1.53 0.782 15 719 exclusion phecode
573.3 Hepatomegaly Digestive 1.11 0.947 – 1.3 0.195 145 2103 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1 0.916 – 1.1 0.954 498 6264 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.04 0.999 – 1.09 0.0564 2045 24822 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.09 0.911 – 1.3 0.354 118 1416 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.02 1 – 1.04 0.0514 9995 116039 exclusion phecode
574.1 Cholelithiasis Digestive 1.01 0.991 – 1.04 0.258 8674 100916 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.966 0.902 – 1.03 0.32 915 10927 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.04 1 – 1.07 0.0434 3535 40608 exclusion phecode
574.2 Calculus of bile duct Digestive 1.06 1.01 – 1.12 0.019 1591 19218 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.02 0.973 – 1.07 0.381 1684 20184 exclusion phecode
575 Other biliary tract disease Digestive 1.04 0.995 – 1.08 0.0821 2417 28197 exclusion phecode
575.1 Cholangitis Digestive 1 0.881 – 1.14 0.991 246 3359 exclusion phecode
575.2 Obstruction of bile duct Digestive 1 0.912 – 1.1 0.975 469 5513 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 1.01 0.902 – 1.13 0.882 329 3555 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.04 0.968 – 1.11 0.313 903 10419 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.08 1 – 1.17 0.048 629 7533 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.03 0.9 – 1.19 0.632 201 2448 exclusion phecode
577 Diseases of pancreas Digestive 1.06 1.01 – 1.12 0.016 1539 18975 exclusion phecode
577.1 Acute pancreatitis Digestive 1.07 1.01 – 1.14 0.0149 1156 14294 exclusion phecode
577.2 Chronic pancreatitis Digestive 0.996 0.885 – 1.12 0.953 289 3652 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.04 0.907 – 1.19 0.581 214 2618 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.997 – 1.03 0.113 14019 150844 exclusion phecode
578.1 Hematemesis Digestive 0.994 0.936 – 1.06 0.854 1103 13997 exclusion phecode
578.2 Blood in stool Digestive 1 0.953 – 1.06 0.914 1574 18437 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.02 0.999 – 1.04 0.0669 9164 96331 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.992 0.958 – 1.03 0.628 3559 38564 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.07 1 – 1.14 0.0503 915 11399 exclusion phecode
579.2 Splenomegaly Digestive 1.19 1.02 – 1.37 0.0225 164 2991 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.03 0.965 – 1.09 0.422 1127 11968 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.14 1.02 – 1.26 0.0187 320 10528 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.18 1.03 – 1.35 0.0181 189 7088 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.95 0.621 – 1.45 0.813 18 560 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.955 0.699 – 1.31 0.775 37 957 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.24 1.07 – 1.45 0.00578 140 5813 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.13 0.944 – 1.34 0.187 113 3276 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.958 0.752 – 1.22 0.728 66 1741 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.952 0.749 – 1.21 0.69 67 1798 exclusion phecode
585 Renal failure Genitourinary 1.08 1.04 – 1.13 0.000115 2224 47440 exclusion phecode
585.1 Acute renal failure Genitourinary 1.07 1.02 – 1.12 0.00815 1647 30586 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.1 1 – 1.21 0.0475 407 10013 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.1 1 – 1.2 0.0424 445 17878 exclusion phecode
585.31 Renal dialysis Genitourinary 1.22 0.984 – 1.52 0.0696 67 3525 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.03 0.981 – 1.08 0.236 1613 23513 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.04 0.793 – 1.37 0.766 46 1460 exclusion phecode
586.11 Small kidney Genitourinary 1.14 0.846 – 1.52 0.398 38 1242 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.04 0.965 – 1.13 0.285 653 8642 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.06 0.732 – 1.54 0.757 26 569 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.01 0.923 – 1.11 0.789 473 6532 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.24 0.875 – 1.75 0.228 24 2697 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 0.973 0.636 – 1.49 0.9 21 735 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 0.848 0.619 – 1.16 0.304 42 808 exclusion phecode
590 Pyelonephritis Genitourinary 1.05 0.978 – 1.13 0.175 801 10146 exclusion phecode
591 Urinary tract infection Genitourinary 0.995 0.972 – 1.02 0.691 7516 88690 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.01 0.967 – 1.06 0.584 1928 21171 exclusion phecode
592.1 Cystitis Genitourinary 1 0.958 – 1.05 0.868 1886 20769 exclusion phecode
592.11 Acute cystitis Genitourinary 1.02 0.825 – 1.26 0.85 86 944 exclusion phecode
592.12 Chronic cystitis Genitourinary 0.987 0.907 – 1.08 0.768 577 6386 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.02 0.871 – 1.19 0.836 173 1820 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.17 0.984 – 1.39 0.0757 121 1186 exclusion phecode
593 Hematuria Genitourinary 0.973 0.953 – 0.993 0.00783 10355 112993 exclusion phecode
594 Urinary calculus Genitourinary 0.977 0.946 – 1.01 0.166 3976 45158 exclusion phecode
594.1 Calculus of kidney Genitourinary 0.99 0.945 – 1.04 0.66 1936 22297 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 0.902 0.816 – 0.996 0.0418 430 5060 exclusion phecode
594.3 Calculus of ureter Genitourinary 0.98 0.93 – 1.03 0.464 1479 17012 exclusion phecode
594.8 Renal colic Genitourinary 0.995 0.942 – 1.05 0.872 1333 14789 exclusion phecode
595 Hydronephrosis Genitourinary 0.997 0.936 – 1.06 0.919 1061 13692 exclusion phecode
596 Other disorders of bladder Genitourinary 1.02 0.991 – 1.04 0.213 6147 66514 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 0.983 0.927 – 1.04 0.565 1187 12461 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1 0.945 – 1.07 0.885 1093 12035 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.03 0.988 – 1.07 0.168 2569 27514 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.02 0.977 – 1.07 0.354 2151 23144 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.08 0.795 – 1.47 0.625 38 544 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 0.995 0.953 – 1.04 0.828 2262 24317 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.95 0.808 – 1.12 0.532 158 2095 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1 0.983 – 1.02 0.923 12379 133880 exclusion phecode
599.1 Urinary obstruction Genitourinary 1.01 0.809 – 1.26 0.935 79 1139 exclusion phecode
599.2 Retention of urine Genitourinary 1.03 1 – 1.07 0.0369 3915 44012 exclusion phecode
599.3 Dysuria Genitourinary 0.992 0.921 – 1.07 0.838 767 8611 exclusion phecode
599.4 Urinary incontinence Genitourinary 0.999 0.973 – 1.03 0.934 6225 66676 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.02 0.977 – 1.06 0.411 2659 28363 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.14 0.845 – 1.53 0.397 37 695 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 0.985 0.712 – 1.36 0.925 37 432 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1.04 0.986 – 1.1 0.143 1246 13115 exclusion phecode
600 Hyperplasia of prostate Genitourinary 1.01 0.985 – 1.04 0.432 6386 55946 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 1.04 0.986 – 1.1 0.139 1239 13404 exclusion phecode
601.1 Prostatitis Genitourinary 1.08 1.02 – 1.16 0.0133 935 9926 exclusion phecode
601.11 Acute prostatitis Genitourinary 1.01 0.851 – 1.19 0.926 135 1527 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1.06 0.977 – 1.16 0.152 548 5689 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 1.11 0.826 – 1.5 0.478 45 421 exclusion phecode
601.4 Balanoposthitis Genitourinary 0.985 0.848 – 1.15 0.848 179 1907 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.985 0.841 – 1.15 0.849 168 2013 exclusion phecode
602 Other disorders of prostate Genitourinary 1.03 0.961 – 1.11 0.394 787 8223 exclusion phecode
603 Other disorders of testis Genitourinary 0.98 0.927 – 1.04 0.482 1349 14624 exclusion phecode
603.1 Hydrocele Genitourinary 0.955 0.889 – 1.03 0.202 832 8911 exclusion phecode
604 Disorders of penis Genitourinary 1.02 0.981 – 1.07 0.276 2065 22593 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.993 0.945 – 1.04 0.785 1692 18724 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 1.02 0.878 – 1.19 0.785 168 1816 exclusion phecode
608 Other disorders of male genital organs Genitourinary 1.03 0.987 – 1.08 0.161 1823 19075 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.981 0.826 – 1.17 0.829 135 1361 exclusion phecode
609.1 Infertility, male Genitourinary 1.04 0.778 – 1.4 0.772 49 503 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.961 0.788 – 1.17 0.694 99 1002 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.993 0.947 – 1.04 0.754 1972 19921 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.998 0.924 – 1.08 0.957 722 7285 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1.05 0.921 – 1.2 0.458 238 2420 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 0.942 0.819 – 1.08 0.395 235 2364 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.977 0.918 – 1.04 0.467 1121 11242 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.03 0.941 – 1.13 0.525 522 5394 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.03 0.973 – 1.09 0.294 1239 12358 exclusion phecode
611.1 Abnormal mammogram Genitourinary 1.07 0.798 – 1.45 0.637 48 428 exclusion phecode
611.3 Lump or mass in breast Genitourinary 1.04 0.978 – 1.1 0.225 1195 11952 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1 0.929 – 1.09 0.908 675 7059 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.993 0.916 – 1.08 0.872 644 6692 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 1.16 0.9 – 1.49 0.256 62 597 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.966 0.91 – 1.03 0.259 1213 13058 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 0.932 0.85 – 1.02 0.135 519 5681 exclusion phecode
613.5 Mastodynia Genitourinary 0.746 0.546 – 1.02 0.0653 52 617 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 1.03 0.943 – 1.13 0.506 543 5480 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 0.99 0.868 – 1.13 0.884 252 2598 exclusion phecode
613.9 Breast disorder NOS Genitourinary – 154 1613 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.978 0.948 – 1.01 0.166 4555 46930 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.964 0.92 – 1.01 0.124 2029 21054 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.992 0.916 – 1.07 0.848 674 6917 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.03 0.757 – 1.4 0.858 50 511 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.971 0.868 – 1.09 0.605 335 3472 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.04 0.921 – 1.18 0.509 284 2951 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.986 0.858 – 1.13 0.841 219 2266 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.987 0.943 – 1.03 0.588 2070 21159 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.994 0.932 – 1.06 0.846 1039 10678 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.04 0.933 – 1.17 0.456 334 3428 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.94 0.863 – 1.02 0.15 632 6251 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.06 0.92 – 1.22 0.424 205 2238 exclusion phecode
615 Endometriosis Genitourinary 0.98 0.945 – 1.02 0.266 3310 33907 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.1 0.969 – 1.26 0.138 222 2413 exclusion phecode
618 Genital prolapse Genitourinary 1.01 0.991 – 1.03 0.263 8798 89103 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 1.02 0.988 – 1.04 0.284 5502 56218 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.01 0.981 – 1.05 0.44 4144 40977 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.03 0.929 – 1.15 0.551 373 3802 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.99 0.899 – 1.09 0.837 475 5087 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1.01 0.982 – 1.03 0.588 6911 70025 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.02 0.935 – 1.11 0.682 582 5971 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 0.989 0.949 – 1.03 0.602 2576 26151 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.03 0.991 – 1.08 0.124 2316 23245 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.04 0.979 – 1.09 0.221 1403 14196 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.981 0.92 – 1.05 0.55 1065 10872 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1.11 0.847 – 1.47 0.438 51 574 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.979 0.911 – 1.05 0.563 819 8975 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.999 0.976 – 1.02 0.916 8117 82727 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.991 0.965 – 1.02 0.517 5988 62113 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 0.998 0.959 – 1.04 0.922 2767 26862 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.03 0.969 – 1.1 0.319 1009 10437 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.991 0.91 – 1.08 0.826 582 6032 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 1.02 0.871 – 1.19 0.817 171 1815 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 1 0.891 – 1.12 0.991 320 3333 exclusion phecode
624.9 stress incontinence, female Genitourinary 0.996 0.966 – 1.03 0.811 4407 45979 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.993 0.951 – 1.04 0.742 2427 24139 exclusion phecode
625.1 Dyspareunia Genitourinary 1.02 0.95 – 1.09 0.643 990 9975 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1 0.986 – 1.02 0.614 13511 95319 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.01 0.99 – 1.03 0.33 11804 91590 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.973 0.776 – 1.22 0.815 86 937 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1.02 0.994 – 1.04 0.143 8024 77074 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.991 0.94 – 1.04 0.721 1612 16218 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 1.01 0.973 – 1.05 0.62 3186 32196 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.978 0.925 – 1.03 0.424 1464 15245 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 1.19 1 – 1.42 0.0479 119 1378 exclusion phecode
626.8 Infertility, female Genitourinary 0.968 0.911 – 1.03 0.3 1228 12044 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.02 0.992 – 1.04 0.211 7565 79145 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 1.01 0.986 – 1.04 0.399 6532 68560 exclusion phecode
627.2 Symptomatic menopause Genitourinary 1.13 0.955 – 1.33 0.159 136 1443 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.02 0.944 – 1.09 0.684 797 8226 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1.07 0.937 – 1.22 0.325 241 2526 exclusion phecode
628 Ovarian cyst Genitourinary 0.99 0.957 – 1.02 0.551 3823 39143 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.979 0.948 – 1.01 0.187 4734 32491 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.02 0.955 – 1.09 0.558 1022 10166 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.01 0.9 – 1.14 0.814 301 2930 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.996 0.947 – 1.05 0.871 1817 15648 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.984 0.911 – 1.06 0.674 798 7773 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1 0.94 – 1.06 0.993 1167 11078 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.02 0.97 – 1.06 0.518 2145 17938 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 1.02 0.936 – 1.12 0.626 563 5515 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.01 0.944 – 1.08 0.788 985 9563 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 1 0.752 – 1.33 0.997 61 625 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.98 0.916 – 1.05 0.569 981 10029 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.07 0.941 – 1.21 0.31 271 2751 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.806 0.681 – 0.953 0.0117 185 1948 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.903 0.747 – 1.09 0.295 131 1363 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 1 0.943 – 1.07 0.906 1147 11281 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.999 0.953 – 1.05 0.983 2016 18854 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.04 0.812 – 1.34 0.742 59 600 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.14 1 – 1.29 0.0426 258 2476 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.984 0.803 – 1.21 0.879 103 1010 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.01 0.857 – 1.18 0.928 176 1744 exclusion phecode
650 Normal delivery Pregnancy Complications 0.997 0.948 – 1.05 0.918 1772 17119 exclusion phecode
651 Multiple gestation Pregnancy Complications 0.964 0.854 – 1.09 0.558 310 3126 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.976 0.925 – 1.03 0.382 1590 14954 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.987 0.93 – 1.05 0.68 1281 12312 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.39 1.08 – 1.77 0.00948 66 656 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.973 0.939 – 1.01 0.125 3940 26537 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.09 0.892 – 1.34 0.39 95 977 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.936 0.891 – 0.982 0.007 2086 16594 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.942 0.853 – 1.04 0.232 492 4803 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.982 0.951 – 1.01 0.281 4864 26481 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.99 0.946 – 1.03 0.65 2333 19087 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.87 0.719 – 1.05 0.152 146 1472 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1 0.874 – 1.14 0.997 241 2368 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.02 0.766 – 1.35 0.901 58 565 exclusion phecode
679 Complications of in utero procedures Dermatologic 1.13 0.841 – 1.52 0.418 48 490 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.04 1.01 – 1.07 0.0148 4027 51507 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.933 0.835 – 1.04 0.224 353 4109 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.04 0.934 – 1.16 0.469 346 3838 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.04 0.998 – 1.07 0.0652 2928 38974 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.04 0.999 – 1.08 0.0544 2932 39017 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.04 0.999 – 1.08 0.0567 2904 38675 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.15 1.04 – 1.28 0.00541 358 4375 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.15 1.07 – 1.23 5.99e-05 807 9636 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.04 0.989 – 1.1 0.118 1475 17138 exclusion phecode
686.3 Pilonidal cyst Dermatologic 0.997 0.9 – 1.1 0.947 404 4550 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 0.871 0.762 – 0.996 0.0434 255 2627 exclusion phecode
687 Symptoms affecting skin Dermatologic 1.1 0.993 – 1.23 0.0671 351 3979 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.02 0.968 – 1.08 0.405 1288 15623 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.15 0.999 – 1.33 0.0519 195 2039 exclusion phecode
687.3 Changes in skin texture Dermatologic 1.08 0.853 – 1.38 0.512 71 794 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.04 0.991 – 1.09 0.114 1962 21730 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.976 0.945 – 1.01 0.147 3950 41432 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.906 0.671 – 1.22 0.52 46 529 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.814 0.561 – 1.18 0.28 36 386 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.823 0.641 – 1.06 0.127 80 876 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.946 0.875 – 1.02 0.165 723 7202 exclusion phecode
694.1 Vitiligo Dermatologic 0.848 0.589 – 1.22 0.374 39 445 exclusion phecode
694.2 Other dyschromia Dermatologic 0.935 0.858 – 1.02 0.128 597 5704 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.12 0.881 – 1.42 0.357 68 847 exclusion phecode
695 Erythematous conditions Dermatologic 0.996 0.945 – 1.05 0.882 1513 17392 exclusion phecode
695.1 Toxic erythema Dermatologic 1.1 0.869 – 1.4 0.424 66 829 exclusion phecode
695.2 Bullous dermatoses Dermatologic 0.946 0.758 – 1.18 0.621 87 966 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 0.908 0.648 – 1.27 0.572 36 395 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.03 0.772 – 1.37 0.853 48 516 exclusion phecode
695.3 Rosacea Dermatologic 1.09 0.949 – 1.24 0.23 224 2212 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.01 0.878 – 1.16 0.902 219 3148 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.833 0.647 – 1.07 0.155 71 955 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1 0.863 – 1.17 0.952 179 2643 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 0.979 0.895 – 1.07 0.647 527 5652 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 0.949 0.802 – 1.12 0.543 146 1752 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.727 0.533 – 0.99 0.0429 55 604 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 0.985 0.869 – 1.12 0.807 280 3288 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.987 0.934 – 1.04 0.655 1320 16391 exclusion phecode
696.4 Psoriasis Dermatologic 0.99 0.936 – 1.05 0.735 1285 16044 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.984 0.921 – 1.05 0.637 954 12132 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 1.03 0.939 – 1.14 0.501 450 5291 exclusion phecode
697 Sarcoidosis Dermatologic 1.14 1.01 – 1.28 0.0305 268 4024 exclusion phecode
698 Pruritus and related conditions Dermatologic 1 0.918 – 1.09 0.982 550 5719 exclusion phecode
700 Corns and callosities Dermatologic 0.977 0.841 – 1.14 0.764 185 2154 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.01 0.977 – 1.05 0.505 3312 34327 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.884 0.663 – 1.18 0.397 54 590 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.02 0.967 – 1.07 0.534 1716 17453 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 1.26 0.931 – 1.7 0.135 38 428 exclusion phecode
701.4 Keloid scar Dermatologic 0.939 0.797 – 1.11 0.453 162 1675 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1.06 0.947 – 1.18 0.317 338 3396 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 0.947 0.734 – 1.22 0.679 64 767 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.993 0.961 – 1.03 0.694 3821 38063 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.991 0.944 – 1.04 0.729 1753 17669 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.994 0.951 – 1.04 0.778 2208 21594 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.03 0.898 – 1.18 0.696 230 2525 exclusion phecode
703.1 Ingrowing nail Dermatologic 1.12 1.03 – 1.21 0.00555 620 7152 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 1.04 1.01 – 1.07 0.019 3837 39206 exclusion phecode
704.1 Alopecia Dermatologic 0.913 0.725 – 1.15 0.435 83 992 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.06 0.829 – 1.35 0.644 58 561 exclusion phecode
705 Disorders of sweat glands Dermatologic 1.07 0.906 – 1.26 0.424 139 1822 exclusion phecode
705.3 Hidradenitis Dermatologic 1.01 0.842 – 1.22 0.884 114 1494 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.16 1.04 – 1.28 0.00527 361 4228 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1.04 1.01 – 1.07 0.00568 6063 61421 exclusion phecode
706.1 Acne Dermatologic 1.41 1.09 – 1.83 0.00856 57 622 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1.02 0.998 – 1.05 0.0691 6421 64821 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.05 0.982 – 1.13 0.154 823 13259 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.01 0.915 – 1.11 0.88 426 6025 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 1.02 0.978 – 1.07 0.346 2182 24985 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.11 0.984 – 1.25 0.0879 260 3817 exclusion phecode
709.3 Systemic sclerosis Dermatologic 1.1 0.896 – 1.34 0.366 90 1293 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.3 0.949 – 1.78 0.103 32 505 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.996 0.949 – 1.04 0.869 1812 19648 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.09 0.974 – 1.23 0.129 290 4237 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.07 0.948 – 1.21 0.273 266 3944 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.1 0.905 – 1.35 0.328 99 1413 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.06 0.913 – 1.23 0.45 176 2796 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 1.11 0.977 – 1.25 0.111 246 3048 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.15 0.993 – 1.32 0.0619 183 2351 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.4 1.07 – 1.84 0.0148 46 569 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.21 0.96 – 1.53 0.106 65 1078 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.39 0.896 – 2.17 0.141 15 445 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.04 0.999 – 1.08 0.0546 2698 35492 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.03 0.99 – 1.07 0.144 2421 32196 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.978 0.917 – 1.04 0.492 1023 12060 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.96 0.756 – 1.22 0.736 72 897 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.04 0.943 – 1.16 0.404 379 4404 exclusion phecode
716 Other arthropathies Musculoskeletal 1.03 1.02 – 1.05 2.1e-06 23477 196989 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.03 0.984 – 1.08 0.211 2074 25167 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.03 1.01 – 1.05 0.00349 9596 111168 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.03 1.02 – 1.05 5.64e-06 22494 194363 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.05 0.965 – 1.13 0.274 598 7700 exclusion phecode
720 Spinal stenosis Musculoskeletal 1.06 1.01 – 1.1 0.00862 2203 25800 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1.01 0.985 – 1.04 0.358 4838 55921 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.01 0.976 – 1.05 0.517 3110 35929 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.962 0.79 – 1.17 0.697 109 1333 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 1.04 0.906 – 1.19 0.581 211 2495 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.04 1.02 – 1.07 0.00152 6074 66959 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.02 0.919 – 1.14 0.692 377 3878 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.07 1.02 – 1.12 0.00498 1811 21082 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 0.934 0.691 – 1.26 0.657 47 524 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.06 1.02 – 1.1 0.00281 2998 32921 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.13 1.01 – 1.25 0.0329 335 3762 exclusion phecode
723.1 Torticollis Musculoskeletal 1.12 0.907 – 1.4 0.285 79 818 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.05 0.999 – 1.11 0.0528 1386 15228 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 0.998 0.889 – 1.12 0.973 307 3198 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.989 0.881 – 1.11 0.853 311 3212 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.13 0.837 – 1.53 0.419 39 439 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.07 1.01 – 1.14 0.0319 1061 11786 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1 0.983 – 1.02 0.726 10176 107805 exclusion phecode
726.1 Enthesopathy Musculoskeletal 1.01 0.984 – 1.04 0.459 6550 69785 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.886 0.777 – 1.01 0.0729 266 2591 exclusion phecode
726.3 Bursitis Musculoskeletal 1 0.922 – 1.09 0.934 564 6223 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1 0.974 – 1.03 0.902 5229 54739 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.987 0.941 – 1.04 0.598 1873 20440 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.974 0.775 – 1.22 0.82 77 733 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1 0.962 – 1.05 0.848 2325 23560 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 1.05 0.949 – 1.16 0.341 375 4137 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 1.03 0.9 – 1.17 0.707 242 2529 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.965 0.783 – 1.19 0.74 99 1022 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.998 0.958 – 1.04 0.943 2465 24188 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.11 0.991 – 1.24 0.0714 308 3266 exclusion phecode
728.7 Fasciitis Musculoskeletal 1.01 0.966 – 1.05 0.783 2559 25266 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.995 0.954 – 1.04 0.828 2348 22728 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.04 1 – 1.07 0.042 3620 44027 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.02 0.943 – 1.11 0.59 655 7817 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.92 0.726 – 1.17 0.49 77 746 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.988 0.851 – 1.15 0.877 196 2119 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.983 0.844 – 1.15 0.828 186 2012 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.964 0.861 – 1.08 0.526 344 3573 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.854 0.714 – 1.02 0.0837 145 1541 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.15 0.857 – 1.53 0.357 43 451 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.993 0.935 – 1.05 0.805 1196 13157 exclusion phecode
733.2 Cyst of bone Musculoskeletal 0.944 0.821 – 1.09 0.423 225 2302 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.04 0.924 – 1.16 0.539 316 3935 exclusion phecode
733.6 Costochondritis Musculoskeletal 1.13 0.918 – 1.38 0.254 85 939 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.01 0.943 – 1.09 0.724 820 9217 exclusion phecode
733.9 Chondromalacia Musculoskeletal 0.778 0.618 – 0.98 0.0328 93 930 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1.01 0.982 – 1.03 0.611 6982 71984 exclusion phecode
735.1 Flat foot Musculoskeletal 1.08 0.907 – 1.29 0.386 122 1423 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 1.02 0.982 – 1.05 0.35 3551 37254 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.05 0.994 – 1.11 0.0826 1329 14089 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 1 0.942 – 1.06 0.971 1142 11378 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.01 0.978 – 1.04 0.638 4947 50311 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1.01 0.949 – 1.08 0.729 1006 11671 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.06 0.905 – 1.23 0.483 171 1820 exclusion phecode
737 Curvature of spine Musculoskeletal 1 0.93 – 1.09 0.907 691 8211 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1 0.925 – 1.09 0.961 649 7702 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1 0.948 – 1.06 0.87 1249 13821 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.958 0.896 – 1.03 0.217 955 10770 exclusion phecode
739 Contracture of joint Musculoskeletal 0.979 0.873 – 1.1 0.72 306 3667 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.03 1.02 – 1.05 1.98e-05 17376 166682 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.03 1.01 – 1.05 0.000665 11040 119049 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.03 1.01 – 1.06 0.0169 5522 62406 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.01 0.884 – 1.16 0.87 227 2490 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.01 0.906 – 1.13 0.834 343 4215 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.04 1.01 – 1.06 0.00305 7456 87250 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.05 1.01 – 1.1 0.0126 2324 25926 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 1.07 0.835 – 1.37 0.59 68 725 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.07 0.977 – 1.18 0.143 450 4582 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 1.15 0.927 – 1.42 0.209 79 1092 exclusion phecode
741.4 Joint effusions Musculoskeletal 1.07 0.997 – 1.14 0.0603 843 10050 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.2 0.952 – 1.52 0.122 68 795 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.962 0.696 – 1.33 0.817 37 413 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.03 0.984 – 1.08 0.204 2079 21769 exclusion phecode
742.1 Loose body in joint Musculoskeletal 1.14 0.998 – 1.29 0.0534 236 2417 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.01 0.795 – 1.27 0.964 75 790 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.09 0.982 – 1.22 0.103 350 3839 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 1.01 0.956 – 1.06 0.741 1489 15364 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.02 0.991 – 1.05 0.184 4923 54050 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.01 0.979 – 1.04 0.522 4147 45488 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.01 0.976 – 1.04 0.564 3611 39824 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1.03 0.922 – 1.15 0.613 319 3471 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.02 0.899 – 1.15 0.81 281 3692 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.08 0.994 – 1.17 0.0689 583 6068 exclusion phecode
745 Pain in joint Musculoskeletal 1.01 0.982 – 1.04 0.505 5204 58798 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.99 0.941 – 1.04 0.691 1632 19231 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.99 0.939 – 1.04 0.71 1509 17983 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.947 0.853 – 1.05 0.305 413 4430 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.959 0.81 – 1.13 0.624 152 1731 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.01 0.948 – 1.08 0.714 929 11802 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.988 0.824 – 1.18 0.894 116 1230 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.23 0.885 – 1.7 0.221 35 360 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.19 1.04 – 1.37 0.00919 226 2300 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 1 0.906 – 1.1 0.996 420 4857 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.06 0.925 – 1.22 0.399 206 2222 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.953 0.793 – 1.15 0.61 122 1296 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.974 0.846 – 1.12 0.715 210 2597 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.951 0.808 – 1.12 0.549 158 1622 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.895 0.665 – 1.2 0.464 46 877 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.968 0.904 – 1.04 0.354 905 11418 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.917 0.836 – 1.01 0.0665 537 5406 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.957 0.857 – 1.07 0.428 372 3782 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.895 0.755 – 1.06 0.199 155 1519 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.03 0.931 – 1.14 0.548 370 6043 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 1.23 1.05 – 1.44 0.0117 133 3003 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.955 0.823 – 1.11 0.544 186 2457 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.94 0.819 – 1.08 0.378 231 2580 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.03 0.885 – 1.2 0.692 180 2025 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.992 0.834 – 1.18 0.925 145 1665 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.783 0.575 – 1.07 0.122 54 593 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.11 0.888 – 1.38 0.366 81 953 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.04 0.776 – 1.38 0.81 47 581 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.922 0.724 – 1.17 0.506 72 859 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.04 0.928 – 1.17 0.486 306 3285 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.08 0.917 – 1.27 0.363 153 1554 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.912 0.746 – 1.11 0.364 114 1299 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.843 0.653 – 1.09 0.192 76 870 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.965 0.872 – 1.07 0.488 414 4400 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.913 0.694 – 1.2 0.518 60 635 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.01 0.895 – 1.13 0.9 297 3254 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.16 0.94 – 1.42 0.169 88 1308 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.16 0.85 – 1.59 0.343 36 648 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.01 0.85 – 1.2 0.92 133 1586 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.07 0.84 – 1.35 0.601 64 704 exclusion phecode
760 Back pain Symptoms 1.03 1.01 – 1.05 0.017 7241 82599 exclusion phecode
761 Cervicalgia Symptoms 0.981 0.925 – 1.04 0.525 1226 13386 exclusion phecode
764 Sciatica Symptoms 1.05 0.995 – 1.1 0.0767 1561 17542 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.07 0.993 – 1.15 0.0768 749 8615 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.13 1.03 – 1.24 0.0127 414 4712 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.992 0.911 – 1.08 0.857 563 6326 exclusion phecode
771.1 Swelling of limb Symptoms 1.04 0.999 – 1.08 0.0589 2688 33176 exclusion phecode
772 Symptoms of the muscles Symptoms 1.04 0.944 – 1.15 0.42 423 4807 exclusion phecode
773 Pain in limb Symptoms 1 0.968 – 1.03 0.995 3953 45671 exclusion phecode
780 Hypothermia/Chills Symptoms 0.994 0.813 – 1.22 0.956 97 1231 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.08 1.02 – 1.14 0.0122 1200 13658 exclusion phecode
782.3 Edema Symptoms 1.06 0.989 – 1.14 0.0953 745 11377 exclusion phecode
782.6 Pallor and flushing Symptoms 1.05 0.867 – 1.26 0.639 119 1247 exclusion phecode
783 Fever of unknown origin Symptoms 1.03 0.989 – 1.07 0.155 2439 28217 exclusion phecode
785 Abdominal pain Symptoms 1.01 1 – 1.03 0.0446 28423 225671 exclusion phecode
788 Syncope and collapse Symptoms 1 0.978 – 1.03 0.75 5658 63507 exclusion phecode
789 Nausea and vomiting Symptoms 1.02 0.996 – 1.04 0.104 7405 85578 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.02 0.828 – 1.26 0.852 87 1038 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 0.876 0.623 – 1.23 0.448 38 573 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.02 0.982 – 1.05 0.37 3644 41750 exclusion phecode
791 Gangrene Symptoms 1.07 0.946 – 1.21 0.276 244 3880 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.959 0.753 – 1.22 0.735 76 727 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1 0.805 – 1.24 0.998 85 945 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 0.982 0.88 – 1.1 0.752 349 3993 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.897 0.721 – 1.12 0.327 96 1018 exclusion phecode
797 Shock Symptoms 1.09 0.884 – 1.36 0.408 77 1011 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.01 0.764 – 1.34 0.942 46 639 exclusion phecode
798 Malaise and fatigue Symptoms 1.01 0.966 – 1.05 0.677 2176 24992 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1.01 0.911 – 1.11 0.92 447 4590 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.02 0.994 – 1.05 0.125 4863 50960 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.02 0.957 – 1.08 0.613 1178 12464 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.18 0.982 – 1.42 0.0766 105 1222 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.05 0.993 – 1.1 0.0897 1569 16175 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 1.09 0.997 – 1.19 0.0584 532 5519 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.02 0.971 – 1.08 0.399 1561 16475 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.05 0.994 – 1.11 0.0809 1313 13664 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.04 0.947 – 1.14 0.422 488 5176 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 1.01 0.988 – 1.04 0.277 6088 61074 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1.02 0.957 – 1.08 0.597 1139 12241 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.02 0.992 – 1.06 0.143 3930 38861 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.01 0.949 – 1.07 0.775 1111 10928 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 1.01 0.968 – 1.05 0.68 2464 24889 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.02 0.954 – 1.09 0.573 927 9901 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 0.972 0.889 – 1.06 0.525 526 5437 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.03 0.962 – 1.1 0.402 887 9451 exclusion phecode
817 Concussion Injuries & Poisonings 1.06 0.911 – 1.23 0.459 180 1822 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.09 0.981 – 1.22 0.108 333 3559 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.03 0.989 – 1.08 0.144 2173 22133 exclusion phecode
823 Torus fracture Injuries & Poisonings 1.06 1 – 1.12 0.0427 1226 12588 exclusion phecode
830 Dislocation Injuries & Poisonings 0.99 0.94 – 1.04 0.709 1519 15494 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 1.02 0.996 – 1.04 0.12 10995 112652 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 1 0.899 – 1.11 0.987 366 3840 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.984 0.885 – 1.1 0.772 358 3560 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.03 0.993 – 1.06 0.117 3428 38344 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.966 0.779 – 1.2 0.75 94 1115 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 0.974 0.861 – 1.1 0.67 276 3525 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.02 0.953 – 1.09 0.567 866 12213 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.986 0.914 – 1.06 0.717 734 8833 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.975 0.931 – 1.02 0.289 1936 22544 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.02 0.973 – 1.07 0.442 2013 23394 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.38 1.04 – 1.84 0.0276 40 530 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.02 0.975 – 1.06 0.451 2338 25149 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.942 0.807 – 1.1 0.445 183 1967 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1.06 0.886 – 1.27 0.525 125 1439 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.04 0.991 – 1.09 0.121 1943 20767 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.04 0.877 – 1.22 0.679 148 1535 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.827 0.612 – 1.12 0.215 48 511 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.03 0.989 – 1.07 0.171 2888 29962 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.11 0.819 – 1.5 0.506 41 369 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.18 0.906 – 1.53 0.224 62 656 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.06 0.884 – 1.27 0.534 118 1315 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.01 0.905 – 1.12 0.873 349 3368 exclusion phecode
873 Broken tooth Injuries & Poisonings 1.12 0.958 – 1.32 0.152 158 1673 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.09 0.886 – 1.33 0.425 87 1237 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.09 0.902 – 1.32 0.365 113 1185 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.03 0.967 – 1.11 0.329 910 9756 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.03 0.991 – 1.07 0.128 2732 30875 exclusion phecode
916 Contusion Injuries & Poisonings 1.03 0.967 – 1.1 0.341 958 10427 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.91 0.757 – 1.09 0.319 134 1399 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.997 0.878 – 1.13 0.963 250 2641 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.904 0.77 – 1.06 0.221 168 1712 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.04 0.983 – 1.1 0.177 1350 15276 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.1 0.94 – 1.3 0.228 152 1568 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.06 0.832 – 1.36 0.621 62 732 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1 0.896 – 1.12 0.957 333 4070 exclusion phecode
947 Urticaria Injuries & Poisonings 1.08 0.951 – 1.22 0.24 249 2770 exclusion phecode
949 Allergies, other Injuries & Poisonings 0.969 0.856 – 1.1 0.621 280 3065 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.978 0.868 – 1.1 0.721 296 3088 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.01 0.86 – 1.19 0.904 158 1935 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1 0.895 – 1.13 0.935 310 3587 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.13 0.818 – 1.57 0.448 30 385 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.75 0.548 – 1.03 0.0737 51 506 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.02 1.01 – 1.04 0.00988 12268 135935 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.03 1.01 – 1.05 0.0059 10735 118729 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.03 0.904 – 1.17 0.675 253 3125 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.977 0.897 – 1.06 0.594 575 6701 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.09 0.946 – 1.25 0.236 192 2752 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.1 0.952 – 1.27 0.198 188 2693 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.98 0.828 – 1.16 0.816 148 1787 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.12 0.944 – 1.32 0.195 121 1978 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.17 0.984 – 1.39 0.0752 116 1929 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.01 0.98 – 1.04 0.476 3968 45867 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.01 0.938 – 1.09 0.775 758 8661 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.09 0.978 – 1.22 0.117 334 3867 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.925 0.811 – 1.05 0.24 253 2948 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.08 0.97 – 1.2 0.16 347 4037 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.07 0.97 – 1.19 0.169 404 4411 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.03 0.978 – 1.09 0.242 1325 15609 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.974 0.806 – 1.18 0.781 121 1510 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.05 0.896 – 1.23 0.539 157 2049 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.967 0.731 – 1.28 0.813 51 670 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.37 1.09 – 1.72 0.00775 66 835 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.17 0.858 – 1.6 0.317 35 711 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.797 0.571 – 1.11 0.181 41 509 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.12 0.802 – 1.56 0.514 39 449 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.94 0.788 – 1.12 0.488 143 1740 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 0.972 0.882 – 1.07 0.57 458 5403 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.949 0.797 – 1.13 0.554 136 1611 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 0.984 0.734 – 1.32 0.913 45 460 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.03 0.797 – 1.33 0.83 61 764 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.92 0.731 – 1.16 0.474 86 877 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.872 0.655 – 1.16 0.346 53 617 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.01 0.968 – 1.06 0.567 2013 21824 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.02 0.973 – 1.08 0.375 1560 21063 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.02 0.973 – 1.08 0.375 1560 21063 exclusion phecode
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