Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Estimated glomerular filtration rate based on cystatin C UK Biobank (UKB) PheWAS analysis

Estimated glomerular filtration rate based on cystatin C — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID exprsweb-egfr-cystatinc-egfrcys-overall-ea-pt-ukb-20211120Legacy PTC+T (DS)Large GWAS

Evaluation cohort: UK Biobank (UKB).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: study-defined normal-range subset.

For this ExPRS, the exclusion sensitivity scan keeps only the study-defined normal-range subset for Estimated glomerular filtration rate based on cystatin C before rerunning the PheWAS. The preserved release does not include numeric bounds for this trait. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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Signal overview

The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.

94 rows visible 17 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.01 0.992 – 1.04 0.223 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 1 0.964 – 1.04 0.888 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.02 0.945 – 1.11 0.567 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 1.03 0.961 – 1.1 0.399 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 0.982 0.755 – 1.28 0.893 55 550 all phecode
010 Tuberculosis Infectious Diseases 0.989 0.845 – 1.16 0.894 166 1659 all phecode
038 Septicemia Infectious Diseases 1.01 0.98 – 1.04 0.473 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 0.988 0.92 – 1.06 0.745 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 1.02 0.927 – 1.11 0.727 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 1.01 0.989 – 1.03 0.426 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.04 1.01 – 1.08 0.0247 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 1 0.953 – 1.06 0.911 1641 16433 all phecode
041.4 E. coli Infectious Diseases 1.04 1 – 1.08 0.0359 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 0.927 0.836 – 1.03 0.15 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.811 0.648 – 1.02 0.0674 95 949 all phecode
054 Herpes simplex Infectious Diseases 1.06 0.921 – 1.21 0.438 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 0.978 0.899 – 1.07 0.615 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 1.04 0.815 – 1.32 0.768 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 1 0.845 – 1.19 0.981 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.02 0.898 – 1.16 0.743 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 0.841 0.737 – 0.959 0.00976 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 0.944 0.855 – 1.04 0.252 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.09 0.924 – 1.28 0.318 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.06 0.888 – 1.27 0.499 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 1.01 0.943 – 1.07 0.862 1004 10036 all phecode
079 Viral infection Infectious Diseases 0.992 0.954 – 1.03 0.705 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 0.906 0.702 – 1.17 0.447 64 640 all phecode
080 Postoperative infection Infectious Diseases 1.01 0.976 – 1.04 0.68 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.04 0.999 – 1.08 0.0531 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.894 0.692 – 1.16 0.392 71 709 all phecode
1000 Burns Injuries & Poisonings 0.943 0.865 – 1.03 0.184 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 1.07 1.01 – 1.14 0.0201 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1 0.977 – 1.03 0.736 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.01 0.897 – 1.13 0.9 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 1.04 0.983 – 1.09 0.189 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 0.941 0.826 – 1.07 0.364 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 1.05 0.928 – 1.19 0.439 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 0.981 0.92 – 1.05 0.552 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 1.02 1 – 1.05 0.0535 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 1 0.975 – 1.03 0.936 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.998 0.977 – 1.02 0.856 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 1.03 0.841 – 1.25 0.798 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.06 0.946 – 1.18 0.328 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.16 0.917 – 1.47 0.215 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 0.965 0.935 – 0.997 0.0308 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.02 1 – 1.03 0.057 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.02 0.906 – 1.15 0.715 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 1.03 0.914 – 1.17 0.603 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.06 0.837 – 1.33 0.65 74 756 all phecode
110.12 Althete's foot Infectious Diseases 0.993 0.837 – 1.18 0.938 141 1410 all phecode
112 Candidiasis Infectious Diseases 0.98 0.937 – 1.02 0.371 2126 21275 all phecode
117 Mycoses Infectious Diseases 0.978 0.863 – 1.11 0.732 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 1 0.854 – 1.18 0.981 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 0.999 0.796 – 1.25 0.996 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 1.03 0.815 – 1.31 0.781 69 689 all phecode
134 Helminthiases Infectious Diseases 1 0.841 – 1.2 0.971 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 0.983 0.806 – 1.2 0.861 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.03 0.897 – 1.19 0.651 205 2050 all phecode
145 Cancer of mouth Neoplasms 0.994 0.916 – 1.08 0.885 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 0.947 0.842 – 1.07 0.366 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.08 0.886 – 1.31 0.452 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 0.967 0.734 – 1.27 0.814 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.897 0.825 – 0.976 0.0111 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 0.86 0.752 – 0.984 0.0287 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 0.913 0.804 – 1.04 0.164 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.979 0.75 – 1.28 0.874 57 570 all phecode
150 Cancer of esophagus Neoplasms 0.92 0.853 – 0.993 0.0316 762 7630 all phecode
151 Cancer of stomach Neoplasms 0.999 0.917 – 1.09 0.988 569 5696 all phecode
153 Colorectal cancer Neoplasms 0.997 0.968 – 1.03 0.866 4580 45799 all phecode
153.2 Colon cancer Neoplasms 1.01 0.974 – 1.05 0.568 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.963 0.922 – 1.01 0.1 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1 0.903 – 1.11 0.998 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.01 0.862 – 1.18 0.896 158 1580 all phecode
157 Pancreatic cancer Neoplasms 0.965 0.89 – 1.05 0.391 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.994 0.933 – 1.06 0.847 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.986 0.959 – 1.01 0.313 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.999 0.863 – 1.16 0.992 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.914 0.79 – 1.06 0.223 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.984 0.851 – 1.14 0.829 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 1.31 1.02 – 1.68 0.0316 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 0.997 0.959 – 1.04 0.887 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.02 0.981 – 1.07 0.285 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 1.07 0.972 – 1.18 0.162 437 4364 all phecode
170.1 Bone cancer Neoplasms 1.24 1.05 – 1.48 0.0136 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 1.02 0.91 – 1.14 0.744 331 3303 all phecode
172 Skin cancer Neoplasms 0.993 0.975 – 1.01 0.416 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.975 0.936 – 1.01 0.21 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 0.978 0.94 – 1.02 0.27 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.992 0.973 – 1.01 0.417 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.07 0.992 – 1.16 0.0788 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.949 0.815 – 1.11 0.507 181 1818 all phecode
174 Breast cancer Neoplasms 1.01 0.988 – 1.02 0.505 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 1.01 0.987 – 1.02 0.571 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 1 0.984 – 1.02 0.795 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.13 0.939 – 1.35 0.201 115 1148 all phecode
175 Acquired absence of breast Neoplasms 0.992 0.951 – 1.03 0.717 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 0.999 0.956 – 1.04 0.965 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 1.01 0.891 – 1.14 0.89 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.985 0.941 – 1.03 0.513 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 0.974 0.919 – 1.03 0.37 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 0.999 0.945 – 1.06 0.958 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.01 0.947 – 1.08 0.734 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.01 0.944 – 1.08 0.791 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.915 0.811 – 1.03 0.145 305 3049 all phecode
185 Cancer of prostate Neoplasms 1.02 0.997 – 1.05 0.0795 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 1.03 0.94 – 1.13 0.507 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.18 0.931 – 1.49 0.172 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.996 0.885 – 1.12 0.946 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1 0.83 – 1.21 0.974 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.01 0.975 – 1.04 0.699 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.998 0.938 – 1.06 0.958 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.994 0.932 – 1.06 0.842 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.06 0.829 – 1.36 0.628 66 660 all phecode
189.2 Cancer of bladder Neoplasms 0.997 0.956 – 1.04 0.873 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.986 0.943 – 1.03 0.54 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 1.03 0.87 – 1.22 0.739 144 1439 all phecode
190 Cancer of eye Neoplasms 0.857 0.729 – 1.01 0.0644 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.969 0.895 – 1.05 0.431 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1 0.916 – 1.09 0.995 566 5650 all phecode
191.11 Cancer of brain Neoplasms 1 0.917 – 1.1 0.929 525 5240 all phecode
193 Thyroid cancer Neoplasms 1.14 1.03 – 1.27 0.0132 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 0.913 0.736 – 1.13 0.405 95 949 all phecode
195 Cancer, suspected or other Neoplasms 0.995 0.98 – 1.01 0.546 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 0.992 0.976 – 1.01 0.317 16267 159497 all phecode
197 Chemotherapy Neoplasms 1.01 0.993 – 1.02 0.304 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 1.01 0.991 – 1.03 0.276 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.02 0.996 – 1.05 0.0911 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.986 0.944 – 1.03 0.523 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.01 0.961 – 1.07 0.663 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.01 0.969 – 1.05 0.695 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.985 0.918 – 1.06 0.688 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.02 0.978 – 1.07 0.335 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.858 0.733 – 1 0.0561 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 0.975 0.923 – 1.03 0.36 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 0.918 0.743 – 1.13 0.425 95 950 all phecode
200 Myeloproliferative disease Neoplasms 0.996 0.933 – 1.06 0.908 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 1.06 0.953 – 1.17 0.295 387 3867 all phecode
201 Hodgkin's disease Neoplasms 0.925 0.812 – 1.05 0.239 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.01 0.97 – 1.06 0.588 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.01 0.962 – 1.06 0.719 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 1.16 1.05 – 1.29 0.00498 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 1.03 0.948 – 1.12 0.483 581 5824 all phecode
204 Leukemia Neoplasms 0.979 0.931 – 1.03 0.417 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 0.968 0.888 – 1.05 0.457 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.984 0.739 – 1.31 0.913 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.957 0.873 – 1.05 0.353 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 0.979 0.889 – 1.08 0.666 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.962 0.859 – 1.08 0.509 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.08 0.913 – 1.28 0.371 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 0.947 0.867 – 1.03 0.223 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 0.996 0.982 – 1.01 0.6 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.952 0.891 – 1.02 0.147 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.03 1 – 1.06 0.0305 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1 0.896 – 1.12 0.978 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.05 0.937 – 1.18 0.39 318 3187 all phecode
214 Lipoma Neoplasms 1 0.976 – 1.03 0.887 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.01 0.981 – 1.04 0.475 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.07 1.01 – 1.14 0.0234 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 1.01 0.983 – 1.03 0.572 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.03 0.947 – 1.11 0.523 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.02 0.942 – 1.11 0.591 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 0.997 0.977 – 1.02 0.805 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 0.995 0.975 – 1.02 0.66 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.912 0.816 – 1.02 0.103 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 0.988 0.936 – 1.04 0.675 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.926 0.805 – 1.06 0.278 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 1.25 1.08 – 1.46 0.00383 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.12 0.965 – 1.3 0.135 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 1.1 0.921 – 1.3 0.302 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.18 0.933 – 1.5 0.167 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.941 0.874 – 1.01 0.107 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.95 0.881 – 1.02 0.181 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.845 0.635 – 1.12 0.247 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.926 0.814 – 1.05 0.241 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.05 0.98 – 1.12 0.163 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.09 0.942 – 1.26 0.248 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.09 0.986 – 1.21 0.09 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.02 0.903 – 1.14 0.802 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.956 0.908 – 1.01 0.0932 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.03 0.99 – 1.08 0.142 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.06 0.976 – 1.15 0.166 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.976 0.917 – 1.04 0.441 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.05 0.953 – 1.15 0.332 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.93 0.858 – 1.01 0.0749 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.01 0.96 – 1.06 0.784 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 0.97 0.881 – 1.07 0.533 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 0.976 0.794 – 1.2 0.815 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 0.985 0.825 – 1.18 0.865 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 0.982 0.965 – 0.999 0.0332 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.06 0.997 – 1.13 0.0643 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.86 0.693 – 1.07 0.172 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.977 0.96 – 0.994 0.00858 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 0.901 0.798 – 1.02 0.0954 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.897 0.78 – 1.03 0.125 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.904 0.785 – 1.04 0.163 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 0.967 0.871 – 1.07 0.527 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 0.995 0.981 – 1.01 0.529 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.959 0.922 – 0.998 0.04 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.856 0.745 – 0.984 0.0285 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.945 0.751 – 1.19 0.634 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.97 0.882 – 1.07 0.524 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 0.947 0.807 – 1.11 0.51 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.992 0.976 – 1.01 0.292 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.13 0.933 – 1.37 0.213 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.17 1.02 – 1.35 0.0238 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1 0.939 – 1.07 0.949 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1 0.915 – 1.1 0.944 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 0.962 0.888 – 1.04 0.341 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.96 0.845 – 1.09 0.526 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.979 0.885 – 1.08 0.69 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.95 0.789 – 1.14 0.589 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.03 0.926 – 1.15 0.569 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.988 0.934 – 1.05 0.675 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 0.938 0.876 – 1 0.065 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.07 0.995 – 1.14 0.0701 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.06 0.982 – 1.14 0.138 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.08 0.915 – 1.28 0.352 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.01 0.938 – 1.1 0.723 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.06 0.916 – 1.23 0.432 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.22 1 – 1.49 0.0468 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.97 0.854 – 1.1 0.636 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.713 0.56 – 0.909 0.00623 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.1 0.944 – 1.29 0.221 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.969 0.892 – 1.05 0.453 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.04 0.897 – 1.21 0.583 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.934 0.762 – 1.14 0.511 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.24 0.985 – 1.55 0.0677 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.971 0.871 – 1.08 0.602 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.973 0.872 – 1.09 0.624 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 0.979 0.857 – 1.12 0.761 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.947 0.821 – 1.09 0.461 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 1.08 0.922 – 1.27 0.34 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.07 0.91 – 1.26 0.4 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.936 0.768 – 1.14 0.51 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 0.956 0.805 – 1.14 0.612 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.971 0.843 – 1.12 0.687 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 0.903 0.671 – 1.22 0.501 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 0.975 0.908 – 1.05 0.48 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 0.986 0.929 – 1.05 0.645 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.02 0.944 – 1.1 0.66 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 0.983 0.893 – 1.08 0.73 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.981 0.779 – 1.23 0.867 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.946 0.828 – 1.08 0.418 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 1.07 0.958 – 1.19 0.234 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.01 0.903 – 1.13 0.84 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.02 0.903 – 1.15 0.746 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 0.985 0.854 – 1.14 0.836 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 0.973 0.804 – 1.18 0.774 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.1 0.877 – 1.39 0.399 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.11 0.946 – 1.3 0.2 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.11 0.935 – 1.32 0.233 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.993 0.982 – 1 0.243 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.993 0.982 – 1 0.23 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.994 0.983 – 1.01 0.355 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1 0.766 – 1.3 1 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.05 0.895 – 1.23 0.56 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.04 0.906 – 1.2 0.57 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.01 0.978 – 1.05 0.522 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 0.996 0.96 – 1.03 0.838 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.08 0.89 – 1.31 0.431 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.08 0.992 – 1.17 0.0759 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.08 0.995 – 1.18 0.0634 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.06 1.02 – 1.11 0.00852 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 1.05 0.972 – 1.14 0.206 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.11 0.997 – 1.23 0.058 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.05 0.988 – 1.11 0.123 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 0.999 0.852 – 1.17 0.993 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.01 0.988 – 1.04 0.316 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.03 0.998 – 1.06 0.0636 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.1 0.971 – 1.26 0.13 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.01 0.958 – 1.05 0.833 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.02 0.951 – 1.09 0.639 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.07 1.02 – 1.13 0.011 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.985 0.927 – 1.05 0.616 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 1 0.94 – 1.07 0.964 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 0.88 0.718 – 1.08 0.222 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 0.989 0.951 – 1.03 0.572 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 1.02 0.93 – 1.12 0.645 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 0.982 0.821 – 1.18 0.845 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1.02 0.951 – 1.09 0.604 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.983 0.884 – 1.09 0.759 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.06 0.932 – 1.21 0.363 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.02 0.771 – 1.36 0.872 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.02 0.996 – 1.04 0.114 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 1.02 0.998 – 1.04 0.0759 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 0.88 0.705 – 1.1 0.259 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.08 0.847 – 1.38 0.53 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.09 0.963 – 1.24 0.17 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1.08 0.947 – 1.24 0.242 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.15 0.971 – 1.36 0.104 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.05 0.922 – 1.2 0.452 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 1.01 0.984 – 1.03 0.559 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.01 0.982 – 1.03 0.624 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.02 0.929 – 1.12 0.66 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 1.03 0.966 – 1.09 0.387 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 1.03 0.965 – 1.09 0.387 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 1.01 0.937 – 1.09 0.79 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.17 1.01 – 1.36 0.0352 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 1.01 0.87 – 1.18 0.862 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 1.03 0.784 – 1.34 0.852 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 0.979 0.831 – 1.15 0.8 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 0.959 0.733 – 1.25 0.759 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.02 0.816 – 1.27 0.877 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.06 0.89 – 1.25 0.533 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.995 0.814 – 1.22 0.959 103 1059 all phecode
284 Aplastic anemia Hematopoietic 1.06 0.964 – 1.17 0.224 435 4357 all phecode
285 Other anemias Hematopoietic 1 0.984 – 1.02 0.805 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.981 0.866 – 1.11 0.756 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.03 0.954 – 1.11 0.453 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.08 0.982 – 1.19 0.111 414 4147 all phecode
286 Coagulation defects Hematopoietic 0.983 0.918 – 1.05 0.63 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 0.934 0.846 – 1.03 0.18 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 0.944 0.758 – 1.18 0.61 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.897 0.792 – 1.02 0.0861 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 0.965 0.748 – 1.24 0.782 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.17 0.947 – 1.45 0.144 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.994 0.896 – 1.1 0.907 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.03 0.982 – 1.09 0.214 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1 0.836 – 1.2 0.98 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 1.23 0.958 – 1.58 0.105 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 1.02 0.965 – 1.07 0.518 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 0.881 0.794 – 0.978 0.0172 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.919 0.724 – 1.17 0.488 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 1.02 0.987 – 1.05 0.232 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 1.01 0.969 – 1.04 0.774 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 1 0.968 – 1.04 0.817 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 1.21 0.955 – 1.52 0.116 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.985 0.917 – 1.06 0.665 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.945 0.837 – 1.07 0.367 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 1 0.964 – 1.04 0.855 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 0.939 0.856 – 1.03 0.178 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 0.994 0.882 – 1.12 0.92 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.09 0.882 – 1.35 0.417 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.999 0.953 – 1.05 0.973 1929 19281 all phecode
290.1 Dementias Mental Disorders 0.978 0.916 – 1.04 0.51 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 1.03 0.934 – 1.14 0.545 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 0.93 0.804 – 1.08 0.333 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.963 0.887 – 1.05 0.364 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.04 0.827 – 1.3 0.754 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.95 0.883 – 1.02 0.164 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.98 0.815 – 1.18 0.831 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.899 0.792 – 1.02 0.0985 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 1.01 0.916 – 1.11 0.843 436 4376 all phecode
292 Neurological disorders Mental Disorders 1.02 0.992 – 1.05 0.148 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.01 0.954 – 1.06 0.832 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.908 0.778 – 1.06 0.22 190 1907 all phecode
292.3 Memory loss Mental Disorders 0.992 0.918 – 1.07 0.839 696 6978 all phecode
292.4 Altered mental status Mental Disorders 1.04 0.997 – 1.09 0.068 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 1.03 0.913 – 1.15 0.673 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 1.01 0.968 – 1.06 0.587 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.981 0.916 – 1.05 0.592 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.979 0.911 – 1.05 0.556 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 0.988 0.907 – 1.08 0.787 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 1.05 0.899 – 1.22 0.554 178 1780 all phecode
295.3 Psychosis Mental Disorders 0.876 0.742 – 1.03 0.119 169 1710 all phecode
296 Mood disorders Mental Disorders 1.02 1 – 1.04 0.0162 12372 123822 all phecode
296.1 Bipolar Mental Disorders 0.999 0.938 – 1.06 0.969 1059 10599 all phecode
296.2 Depression Mental Disorders 1.02 1.01 – 1.04 0.013 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 1.02 0.917 – 1.14 0.691 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.904 0.802 – 1.02 0.0964 311 3070 all phecode
300 Anxiety disorders Mental Disorders 0.995 0.971 – 1.02 0.696 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 0.997 0.972 – 1.02 0.84 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 0.924 0.781 – 1.09 0.357 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.02 0.941 – 1.1 0.666 707 7065 all phecode
300.13 Phobia Mental Disorders 1.01 0.925 – 1.11 0.76 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.879 0.734 – 1.05 0.161 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 1.16 0.884 – 1.52 0.286 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 0.998 0.831 – 1.2 0.981 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.02 0.844 – 1.24 0.823 113 1129 all phecode
301 Personality disorders Mental Disorders 1.15 1.03 – 1.28 0.0142 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.07 0.895 – 1.29 0.445 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 1.03 0.913 – 1.17 0.621 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.02 0.928 – 1.12 0.666 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 0.995 0.89 – 1.11 0.926 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 1.01 0.841 – 1.22 0.91 123 1229 all phecode
304 Adjustment reaction Mental Disorders 0.954 0.843 – 1.08 0.456 293 2936 all phecode
305.2 Eating disorder Mental Disorders 0.949 0.764 – 1.18 0.638 90 900 all phecode
306 Other mental disorder Mental Disorders 1.01 0.993 – 1.02 0.375 28056 230087 all phecode
306.9 Tension headache Mental Disorders 1.04 0.926 – 1.17 0.507 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 0.974 0.776 – 1.22 0.821 76 770 all phecode
313.3 Autism Mental Disorders 1.17 0.908 – 1.51 0.223 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 1 0.898 – 1.12 0.967 351 3517 all phecode
315.1 Learning disorder Mental Disorders 0.909 0.769 – 1.07 0.264 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 0.961 0.768 – 1.2 0.731 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 0.994 0.967 – 1.02 0.691 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.859 0.656 – 1.13 0.27 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 1 0.983 – 1.02 0.94 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 1 0.981 – 1.02 0.826 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 0.972 0.905 – 1.04 0.435 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 0.99 0.975 – 1 0.181 19359 185465 all phecode
320 Meningitis Neurological 0.966 0.876 – 1.07 0.493 444 4447 all phecode
323 Encephalitis Neurological 1.05 0.942 – 1.17 0.387 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 1.12 0.894 – 1.39 0.333 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.16 1.03 – 1.31 0.0129 292 2916 all phecode
327 Sleep disorders Neurological 1.09 1.03 – 1.16 0.00273 1164 11659 all phecode
327.3 Sleep apnea Neurological 1 0.971 – 1.03 0.947 4428 44318 all phecode
327.4 Insomnia Neurological 0.993 0.846 – 1.17 0.935 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 1.06 0.893 – 1.25 0.51 136 1390 all phecode
331 Other cerebral degenerations Neurological 1.01 0.95 – 1.07 0.753 1142 11416 all phecode
331.1 Hydrocephalus Neurological 0.966 0.879 – 1.06 0.467 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 1.07 0.97 – 1.18 0.177 430 4298 all phecode
332 Parkinson's disease Neurological 1.04 0.977 – 1.1 0.224 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.03 0.959 – 1.1 0.439 894 8954 all phecode
333.1 Essential tremor Neurological 1.09 0.947 – 1.24 0.239 216 2157 all phecode
333.2 Myoclonus Neurological 1.1 0.891 – 1.35 0.382 96 958 all phecode
333.4 Torsion dystonia Neurological 0.918 0.804 – 1.05 0.21 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 1.01 0.959 – 1.06 0.769 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 1.15 0.96 – 1.38 0.128 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 1.06 0.934 – 1.21 0.35 245 2446 all phecode
335 Multiple sclerosis Neurological 1.01 0.951 – 1.06 0.821 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 0.983 0.868 – 1.11 0.791 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 0.812 0.631 – 1.04 0.103 72 719 all phecode
338 Pain Neurological 1.08 1 – 1.16 0.0448 768 7692 all phecode
338.1 Acute pain Neurological 1.08 0.98 – 1.2 0.117 394 3937 all phecode
338.2 Chronic pain Neurological 1.04 0.939 – 1.16 0.436 380 3817 all phecode
339 Other headache syndromes Neurological 1.01 0.988 – 1.03 0.368 7819 78241 all phecode
340 Migraine Neurological 0.98 0.943 – 1.02 0.319 2860 28602 all phecode
340.1 Migrain with aura Neurological 0.921 0.798 – 1.06 0.257 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.991 0.871 – 1.13 0.891 252 2535 all phecode
342 Hemiplegia Neurological 1 0.951 – 1.06 0.908 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 0.798 0.667 – 0.955 0.0139 145 1450 all phecode
344 Other paralytic syndromes Neurological 1.05 0.97 – 1.14 0.225 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.01 0.98 – 1.04 0.565 5023 50270 all phecode
345.1 Epilepsy Neurological 1.02 0.954 – 1.1 0.528 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 1.11 1.01 – 1.22 0.0272 439 4385 all phecode
345.12 Partial epilepsy Neurological 0.998 0.882 – 1.13 0.971 277 2776 all phecode
345.3 Convulsions Neurological 0.979 0.937 – 1.02 0.34 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.08 0.911 – 1.27 0.39 144 1438 all phecode
348 Other conditions of brain Neurological 0.971 0.902 – 1.05 0.445 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 0.969 0.853 – 1.1 0.623 268 2678 all phecode
348.4 Cerebral cysts Neurological 1.04 0.872 – 1.24 0.653 133 1350 all phecode
348.7 Coma Neurological 1.02 0.916 – 1.13 0.732 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 0.958 0.839 – 1.09 0.53 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 0.984 0.888 – 1.09 0.761 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.1 0.987 – 1.22 0.0847 342 3414 all phecode
350 Abnormal movement Neurological 1.04 1 – 1.09 0.0334 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 1.02 0.957 – 1.1 0.487 887 8852 all phecode
350.2 Abnormality of gait Neurological 1.05 0.996 – 1.1 0.0723 1596 15969 all phecode
350.3 Lack of coordination Neurological 1.08 0.972 – 1.2 0.153 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.02 0.788 – 1.33 0.861 54 540 all phecode
351 Other peripheral nerve disorders Neurological 1 0.984 – 1.02 0.787 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 1.03 0.976 – 1.09 0.276 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.981 0.891 – 1.08 0.689 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.03 0.964 – 1.11 0.353 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 1 0.941 – 1.06 0.978 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 0.859 0.703 – 1.05 0.138 114 1138 all phecode
353.2 Nerve root lesions Neurological 1.07 0.823 – 1.39 0.62 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.06 0.907 – 1.25 0.448 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.09 1.03 – 1.15 0.00178 1361 13648 all phecode
358 Myoneural disorders Neurological 1.03 0.9 – 1.18 0.646 211 2109 all phecode
358.1 Myasthenia gravis Neurological 1.05 0.914 – 1.22 0.468 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 1.01 0.922 – 1.12 0.772 465 4646 all phecode
359.1 Muscular dystrophies Neurological 0.815 0.67 – 0.99 0.0394 122 1219 all phecode
359.2 Myopathy Neurological 1.07 0.963 – 1.19 0.202 360 3597 all phecode
360 Disorders of the globe Sense Organs 0.996 0.891 – 1.11 0.951 337 3367 all phecode
360.2 Progressive myopia Sense Organs 1.06 0.932 – 1.2 0.388 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 1.03 0.998 – 1.07 0.0667 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.03 0.975 – 1.09 0.291 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.945 0.734 – 1.22 0.658 68 680 all phecode
362 Other retinal disorders Sense Organs 1.02 0.984 – 1.05 0.322 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.02 0.98 – 1.07 0.296 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.02 0.98 – 1.07 0.298 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.08 0.917 – 1.26 0.371 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 1.1 0.899 – 1.34 0.358 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.04 0.967 – 1.11 0.31 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 1.03 0.882 – 1.19 0.742 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.865 0.684 – 1.09 0.225 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.999 0.829 – 1.2 0.993 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.941 0.801 – 1.11 0.46 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 1.03 0.814 – 1.31 0.799 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.03 0.946 – 1.11 0.542 647 6485 all phecode
364.1 Corneal opacity Sense Organs 1.11 0.899 – 1.37 0.337 90 910 all phecode
364.2 Corneal edema Sense Organs 1 0.797 – 1.27 0.968 79 800 all phecode
364.4 Corneal degenerations Sense Organs 1.12 0.975 – 1.29 0.108 201 2017 all phecode
364.41 Keratoconus Sense Organs 1.06 0.856 – 1.3 0.613 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 0.992 0.86 – 1.14 0.909 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.974 0.791 – 1.2 0.806 100 1000 all phecode
365 Glaucoma Sense Organs 1.01 0.981 – 1.04 0.476 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 1.01 0.952 – 1.08 0.666 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.02 0.955 – 1.09 0.578 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.966 0.894 – 1.05 0.393 698 6996 all phecode
366 Cataract Sense Organs 1.01 0.996 – 1.03 0.166 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 0.9 0.703 – 1.15 0.403 69 700 all phecode
366.2 Senile cataract Sense Organs 1.01 0.988 – 1.03 0.347 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 1.16 0.961 – 1.4 0.122 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1.02 0.981 – 1.07 0.281 2408 24092 all phecode
367.1 Myopia Sense Organs 1.03 0.971 – 1.09 0.332 1251 12519 all phecode
367.2 Astigmatism Sense Organs 0.97 0.833 – 1.13 0.699 190 1899 all phecode
367.8 Hypermetropia Sense Organs 1.07 0.938 – 1.21 0.324 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 1.02 0.946 – 1.1 0.585 719 7198 all phecode
368 Visual disturbances Sense Organs 1.03 0.995 – 1.07 0.0863 2962 29648 all phecode
368.1 Amblyopia Sense Organs 0.985 0.901 – 1.08 0.74 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.979 0.907 – 1.06 0.586 727 7288 all phecode
368.3 Anisometropia Sense Organs 1.11 0.947 – 1.3 0.199 154 1548 all phecode
368.4 Visual field defects Sense Organs 1.05 0.938 – 1.17 0.415 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 1.13 1.04 – 1.22 0.00254 612 6115 all phecode
369 Infection of the eye Sense Organs 1.04 0.956 – 1.14 0.343 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 1.03 0.853 – 1.23 0.789 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.922 0.796 – 1.07 0.282 213 2128 all phecode
370 Keratitis Sense Organs 1.01 0.899 – 1.15 0.813 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 0.967 0.813 – 1.15 0.704 141 1408 all phecode
371 Inflammation of the eye Sense Organs 1.02 0.979 – 1.05 0.392 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.05 0.959 – 1.15 0.291 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 0.998 0.956 – 1.04 0.924 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 1 0.931 – 1.08 0.94 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 0.994 0.967 – 1.02 0.668 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 0.956 0.897 – 1.02 0.165 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 0.978 0.932 – 1.03 0.365 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 0.991 0.949 – 1.04 0.691 2204 22031 all phecode
375.2 Epiphora Sense Organs 0.983 0.917 – 1.05 0.627 898 8969 all phecode
376 Disorders of the orbit Sense Organs 0.957 0.767 – 1.19 0.697 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.995 0.892 – 1.11 0.923 361 3618 all phecode
377.1 Optic atrophy Sense Organs 0.995 0.761 – 1.3 0.97 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.945 0.786 – 1.14 0.546 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.977 0.925 – 1.03 0.418 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.957 0.893 – 1.03 0.209 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.989 0.86 – 1.14 0.88 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 1.06 0.935 – 1.2 0.37 275 2755 all phecode
379 Other disorders of eye Sense Organs 0.993 0.96 – 1.03 0.696 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 1.01 0.952 – 1.06 0.813 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.993 0.947 – 1.04 0.785 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.06 0.842 – 1.35 0.601 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.04 0.945 – 1.15 0.399 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.959 0.82 – 1.12 0.606 169 1690 all phecode
380 Disorders of external ear Sense Organs 1.01 0.929 – 1.09 0.874 642 6413 all phecode
380.1 Otitis externa Sense Organs 0.991 0.903 – 1.09 0.843 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 0.984 0.885 – 1.09 0.769 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.961 0.919 – 1.01 0.0824 2150 21493 all phecode
381.1 Otitis media Sense Organs 0.955 0.908 – 1 0.0671 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.987 0.92 – 1.06 0.726 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 0.973 0.839 – 1.13 0.715 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.09 0.936 – 1.27 0.261 171 1709 all phecode
381.9 Otorrhea Sense Organs 0.935 0.825 – 1.06 0.294 281 2807 all phecode
382 Otalgia Sense Organs 1.07 0.954 – 1.2 0.244 308 3084 all phecode
383 Otosclerosis Sense Organs 0.978 0.87 – 1.1 0.704 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.01 0.951 – 1.07 0.824 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.03 0.966 – 1.1 0.377 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.01 0.942 – 1.09 0.735 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 1 0.923 – 1.09 0.949 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 0.985 0.864 – 1.12 0.819 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.06 1.01 – 1.11 0.0173 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 1.13 1.04 – 1.23 0.00362 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 1 0.903 – 1.11 0.956 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 1.02 0.951 – 1.1 0.543 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.01 0.978 – 1.04 0.587 4582 45806 all phecode
388 Other disorders of ear Sense Organs 1.14 0.993 – 1.31 0.0636 202 2017 all phecode
389 Hearing loss Sense Organs 0.993 0.962 – 1.03 0.688 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 1.02 0.929 – 1.13 0.645 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 0.929 0.841 – 1.03 0.146 450 4497 all phecode
389.4 Tinnitus Sense Organs 0.976 0.89 – 1.07 0.596 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.01 0.98 – 1.04 0.524 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 1.02 0.979 – 1.05 0.4 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 1 0.948 – 1.06 0.878 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.03 0.969 – 1.1 0.327 1058 10566 all phecode
395 Heart valve disorders Circulatory System 1.02 0.984 – 1.05 0.341 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.02 0.983 – 1.06 0.292 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.08 0.953 – 1.22 0.226 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.08 0.887 – 1.3 0.458 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 1.04 0.849 – 1.27 0.715 97 970 all phecode
395.6 Heart valve replaced Circulatory System 0.989 0.937 – 1.04 0.685 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 1.06 0.997 – 1.13 0.0637 1048 10468 all phecode
401 Hypertension Circulatory System 0.995 0.987 – 1 0.246 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 0.995 0.987 – 1 0.249 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 0.973 0.928 – 1.02 0.251 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 1.01 0.911 – 1.12 0.832 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.968 0.918 – 1.02 0.226 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 0.956 0.8 – 1.14 0.623 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.02 0.967 – 1.08 0.475 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 0.987 0.975 – 0.999 0.0319 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.991 0.963 – 1.02 0.556 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 0.991 0.972 – 1.01 0.337 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 0.977 0.961 – 0.993 0.00609 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 0.987 0.973 – 1 0.0942 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.943 0.872 – 1.02 0.144 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.99 0.973 – 1.01 0.24 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.01 0.954 – 1.07 0.71 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 0.977 0.931 – 1.03 0.357 1823 18228 all phecode
414.2 ASCVD Circulatory System 0.948 0.743 – 1.21 0.668 72 719 all phecode
415 Pulmonary heart disease Circulatory System 1.01 0.983 – 1.05 0.376 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.07 0.861 – 1.34 0.524 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.07 0.981 – 1.16 0.131 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.05 0.952 – 1.16 0.335 448 4475 all phecode
416 Cardiomegaly Circulatory System 0.995 0.956 – 1.04 0.792 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 1 0.992 – 1.02 0.554 28599 270106 all phecode
418.1 Precordial pain Circulatory System 1 0.968 – 1.04 0.894 3551 35541 all phecode
420 Carditis Circulatory System 1.02 0.978 – 1.07 0.327 2106 21053 all phecode
420.1 Myocarditis Circulatory System 1.04 0.864 – 1.24 0.697 127 1267 all phecode
420.2 Pericarditis Circulatory System 1.05 0.992 – 1.11 0.091 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 1.05 0.92 – 1.2 0.468 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 1.05 0.867 – 1.27 0.629 113 1129 all phecode
420.3 Endocarditis Circulatory System 0.977 0.904 – 1.06 0.558 719 7194 all phecode
425 Cardiomyopathy Circulatory System 0.99 0.935 – 1.05 0.742 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.981 0.925 – 1.04 0.522 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.904 0.753 – 1.08 0.276 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1 0.852 – 1.18 0.979 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 1.22 0.959 – 1.56 0.105 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 0.977 0.953 – 1 0.0682 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 0.955 0.912 – 0.999 0.0459 2114 21162 all phecode
426.21 First degree AV block Circulatory System 0.96 0.898 – 1.03 0.225 986 9867 all phecode
426.23 Second degree AV block Circulatory System 0.997 0.904 – 1.1 0.955 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 0.965 0.886 – 1.05 0.407 587 5868 all phecode
426.25 Other heart block Circulatory System 1.04 0.872 – 1.25 0.639 131 1318 all phecode
426.3 Bundle branch block Circulatory System 0.993 0.958 – 1.03 0.681 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 1 0.953 – 1.06 0.871 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 0.984 0.936 – 1.03 0.516 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.915 0.798 – 1.05 0.201 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.57 1.22 – 2.03 0.000461 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.976 0.936 – 1.02 0.253 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.974 0.933 – 1.02 0.239 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 0.989 0.976 – 1 0.115 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1 0.967 – 1.04 0.891 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.993 0.951 – 1.04 0.733 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.02 0.957 – 1.09 0.504 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 0.992 0.975 – 1.01 0.352 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.987 0.952 – 1.02 0.487 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.988 0.931 – 1.05 0.698 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.922 0.824 – 1.03 0.159 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 1.01 0.944 – 1.07 0.823 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.984 0.921 – 1.05 0.637 952 9541 all phecode
427.6 Premature beats Circulatory System 1.04 0.954 – 1.14 0.368 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 0.91 0.75 – 1.11 0.343 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 0.98 0.937 – 1.02 0.36 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.06 0.957 – 1.17 0.28 402 4029 all phecode
427.9 Palpitations Circulatory System 1 0.967 – 1.03 0.981 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.03 0.999 – 1.06 0.0566 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.03 0.986 – 1.08 0.175 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 1.02 0.993 – 1.06 0.132 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.01 0.935 – 1.09 0.813 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 0.851 0.652 – 1.11 0.231 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.972 0.887 – 1.06 0.539 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.13 0.983 – 1.3 0.0858 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 1.04 0.994 – 1.09 0.0895 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.09 1.01 – 1.17 0.0216 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1.01 0.935 – 1.08 0.851 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 1.02 0.899 – 1.15 0.802 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 0.997 0.975 – 1.02 0.773 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1 0.947 – 1.07 0.871 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.05 0.911 – 1.2 0.526 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.986 0.956 – 1.02 0.392 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.975 0.927 – 1.02 0.315 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 0.986 0.949 – 1.02 0.478 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 0.991 0.948 – 1.04 0.685 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 0.989 0.89 – 1.1 0.838 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.993 0.938 – 1.05 0.822 1279 12783 all phecode
440 Atherosclerosis Circulatory System 0.984 0.931 – 1.04 0.575 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1 0.82 – 1.22 0.991 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.982 0.913 – 1.06 0.624 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 0.977 0.863 – 1.1 0.708 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 0.942 0.866 – 1.02 0.161 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.879 0.773 – 1 0.05 283 2827 all phecode
442 Other aneurysm Circulatory System 1.02 0.969 – 1.06 0.508 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 1.01 0.954 – 1.06 0.796 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.03 0.961 – 1.1 0.437 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.11 0.92 – 1.35 0.27 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.04 0.895 – 1.21 0.605 169 1696 all phecode
442.4 Arterial dissection Circulatory System 1.43 1.12 – 1.82 0.00446 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 0.966 0.837 – 1.11 0.632 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 1.01 0.977 – 1.04 0.571 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 1.04 0.982 – 1.11 0.171 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 0.965 0.868 – 1.07 0.511 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.01 0.974 – 1.04 0.649 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.995 0.955 – 1.04 0.796 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 0.996 0.931 – 1.07 0.904 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.01 0.924 – 1.1 0.874 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.01 0.937 – 1.08 0.861 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 1.1 0.952 – 1.26 0.2 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 1.02 0.917 – 1.13 0.749 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 0.983 0.859 – 1.12 0.802 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 0.951 0.898 – 1.01 0.0844 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 0.996 0.929 – 1.07 0.908 868 8712 all phecode
448 Disease of capillaries Circulatory System 0.966 0.812 – 1.15 0.699 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.04 0.966 – 1.13 0.279 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.01 0.981 – 1.05 0.439 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.02 0.988 – 1.06 0.212 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.986 0.904 – 1.08 0.755 564 5645 all phecode
454 Varicose veins Circulatory System 1 0.982 – 1.02 0.908 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1 0.981 – 1.02 0.985 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.905 0.831 – 0.985 0.0216 624 6325 all phecode
455 Hemorrhoids Circulatory System 1 0.987 – 1.01 0.97 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.948 0.815 – 1.1 0.494 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.07 0.869 – 1.32 0.524 97 967 all phecode
458 Hypotension Circulatory System 1.02 0.997 – 1.05 0.0838 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 1 0.948 – 1.06 0.944 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.02 0.889 – 1.16 0.811 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 1.02 0.985 – 1.06 0.273 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 1 0.984 – 1.02 0.998 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 1.08 0.916 – 1.28 0.353 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 1 0.984 – 1.02 0.986 16103 159422 all phecode
464 Acute sinusitis Respiratory 1.02 0.884 – 1.18 0.757 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.981 0.94 – 1.02 0.396 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 1 0.934 – 1.08 0.92 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 1 0.859 – 1.17 0.972 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.04 1.01 – 1.07 0.0121 4654 46553 all phecode
471 Nasal polyps Respiratory 1.01 0.978 – 1.05 0.481 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.06 0.996 – 1.13 0.0641 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 0.994 0.954 – 1.04 0.766 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 0.925 0.753 – 1.14 0.454 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.04 0.92 – 1.18 0.514 264 2647 all phecode
473.4 Voice disturbance Respiratory 0.978 0.918 – 1.04 0.488 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 1.01 0.96 – 1.06 0.757 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 1.08 0.993 – 1.18 0.0713 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.968 0.91 – 1.03 0.304 1122 11199 all phecode
475 Chronic sinusitis Respiratory 0.994 0.955 – 1.04 0.777 2589 25882 all phecode
476 Allergic rhinitis Respiratory 0.98 0.919 – 1.05 0.542 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 0.98 0.94 – 1.02 0.339 2447 24452 all phecode
478 Throat pain Respiratory 1.08 0.972 – 1.19 0.154 377 3789 all phecode
479 Other upper respiratory disease Respiratory 1.02 0.987 – 1.05 0.235 4074 40737 all phecode
480 Pneumonia Respiratory 1 0.984 – 1.02 0.725 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 1.01 0.983 – 1.03 0.559 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 1 0.977 – 1.03 0.795 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.03 0.836 – 1.26 0.793 93 929 all phecode
480.2 Viral pneumonia Respiratory 0.829 0.639 – 1.07 0.156 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1 0.82 – 1.23 0.963 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.03 0.956 – 1.1 0.462 794 7951 all phecode
481 Influenza Respiratory 0.987 0.881 – 1.11 0.817 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.03 0.889 – 1.2 0.686 193 1930 all phecode
495 Asthma Respiratory 1 0.988 – 1.01 0.907 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 0.889 0.778 – 1.02 0.0863 250 2510 all phecode
496 Chronic airway obstruction Respiratory 0.993 0.973 – 1.01 0.493 10424 101546 all phecode
496.1 Emphysema Respiratory 0.991 0.943 – 1.04 0.709 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 0.989 0.952 – 1.03 0.554 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 0.988 0.95 – 1.03 0.563 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 0.988 0.942 – 1.04 0.62 1885 18859 all phecode
497 Bronchitis Respiratory 0.931 0.855 – 1.01 0.102 626 6267 all phecode
500 Lung disease due to external agents Respiratory 1 0.907 – 1.11 0.974 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.921 0.732 – 1.16 0.482 79 784 all phecode
500.2 Pneumoconiosis Respiratory 0.985 0.864 – 1.12 0.816 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 0.993 0.916 – 1.08 0.864 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.01 0.943 – 1.08 0.805 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 0.86 0.781 – 0.947 0.00208 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.02 0.912 – 1.14 0.713 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 0.971 0.747 – 1.26 0.823 61 610 all phecode
506 Empyema and pneumothorax Respiratory 1.01 0.948 – 1.07 0.797 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 1.01 0.984 – 1.04 0.474 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.982 0.938 – 1.03 0.453 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.02 0.982 – 1.06 0.281 2599 26031 all phecode
509.1 Respiratory failure Respiratory 1.05 0.999 – 1.09 0.0528 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 1.04 0.989 – 1.09 0.137 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 1.08 0.921 – 1.28 0.331 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.929 0.836 – 1.03 0.177 386 3863 all phecode
510 Other diseases of lung Respiratory 1.08 1 – 1.16 0.044 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 1.03 1.01 – 1.05 0.00683 9031 90349 all phecode
512.1 Wheezing Respiratory 0.986 0.855 – 1.14 0.841 220 2196 all phecode
512.2 Painful respiration Respiratory 1.11 0.967 – 1.28 0.134 207 2075 all phecode
512.7 Shortness of breath Respiratory 1.03 1 – 1.06 0.0375 5842 58498 all phecode
512.8 Cough Respiratory 1.04 1 – 1.08 0.0467 2866 28642 all phecode
512.9 Other dyspnea Respiratory 1.01 0.945 – 1.08 0.74 914 9124 all phecode
513 Respiratory abnormalities Respiratory 0.982 0.903 – 1.07 0.675 611 6112 all phecode
513.3 Hypoventilation Respiratory 1.07 0.849 – 1.34 0.581 83 830 all phecode
513.4 Hyperventilation Respiratory 0.941 0.829 – 1.07 0.347 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 1.02 0.867 – 1.21 0.782 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 1.02 0.98 – 1.06 0.32 2465 24673 all phecode
516 Abnormal sputum Respiratory 1.01 0.97 – 1.06 0.536 2132 21335 all phecode
516.1 Hemoptysis Respiratory 1.02 0.973 – 1.06 0.446 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.994 0.973 – 1.02 0.561 9366 93681 all phecode
519.2 Respiratory complications Respiratory 1.08 0.968 – 1.21 0.167 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.989 0.967 – 1.01 0.317 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.01 0.9 – 1.14 0.831 303 3049 all phecode
520 Disorders of tooth development Digestive 0.998 0.954 – 1.04 0.946 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.9 0.675 – 1.2 0.474 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 0.976 0.936 – 1.02 0.267 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 1 0.965 – 1.04 0.917 3016 30245 all phecode
521.1 Dental caries Digestive 1 0.966 – 1.04 0.887 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.02 0.975 – 1.07 0.345 1774 17750 all phecode
522.5 Periapical abscess Digestive 1.03 0.968 – 1.09 0.369 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 1 0.956 – 1.06 0.861 1681 16812 all phecode
523.1 Gingivitis Digestive 1.03 0.857 – 1.24 0.76 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.03 0.968 – 1.09 0.37 1165 11650 all phecode
523.31 Acute periodontitis Digestive 0.996 0.92 – 1.08 0.922 666 6667 all phecode
523.32 Chronic periodontitis Digestive 1.04 0.957 – 1.13 0.345 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.07 0.96 – 1.2 0.22 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.06 0.944 – 1.19 0.323 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.959 0.921 – 0.998 0.0399 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.19 0.95 – 1.49 0.13 72 720 all phecode
526 Diseases of the jaws Digestive 0.999 0.934 – 1.07 0.986 928 9279 all phecode
526.1 Cysts of the jaws Digestive 0.92 0.819 – 1.03 0.155 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.14 0.895 – 1.45 0.292 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.03 0.907 – 1.18 0.622 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.05 0.917 – 1.19 0.504 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.959 0.783 – 1.17 0.687 110 1098 all phecode
526.9 Jaw disease NOS Digestive 1.02 0.891 – 1.17 0.764 233 2329 all phecode
527 Diseases of the salivary glands Digestive 0.997 0.921 – 1.08 0.94 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.11 0.887 – 1.38 0.371 84 838 all phecode
527.2 Sialoadenitis Digestive 0.971 0.871 – 1.08 0.601 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 0.929 0.709 – 1.22 0.596 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 0.975 0.807 – 1.18 0.792 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.997 0.964 – 1.03 0.836 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 1.02 0.932 – 1.13 0.62 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.02 0.918 – 1.13 0.742 389 3884 all phecode
528.12 Oral aphthae Digestive 1.09 0.874 – 1.36 0.44 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.04 0.896 – 1.21 0.589 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 0.91 0.752 – 1.1 0.331 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 0.826 0.661 – 1.03 0.0939 94 940 all phecode
528.5 Diseases of lips Digestive 1.02 0.945 – 1.1 0.588 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 0.869 0.769 – 0.981 0.0232 308 3079 all phecode
528.7 Sialolithiasis Digestive 0.967 0.861 – 1.09 0.575 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 1.01 0.953 – 1.07 0.735 1232 12312 all phecode
529.1 Glossitis Digestive 1.1 0.982 – 1.24 0.0997 299 2986 all phecode
530 Diseases of esophagus Digestive 1 0.989 – 1.01 0.898 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.01 0.994 – 1.02 0.37 31253 272429 all phecode
530.11 GERD Digestive 1.01 0.994 – 1.02 0.294 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 1.02 0.992 – 1.05 0.155 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 1.01 0.993 – 1.03 0.191 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.941 0.894 – 0.99 0.02 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 0.99 0.944 – 1.04 0.67 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 0.979 0.903 – 1.06 0.614 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.966 0.822 – 1.14 0.674 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.948 0.846 – 1.06 0.364 341 3416 all phecode
530.9 Heartburn Digestive 1 0.957 – 1.05 0.967 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.01 0.984 – 1.03 0.515 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.04 0.963 – 1.13 0.301 637 6374 all phecode
531.2 Gastric ulcer Digestive 0.99 0.959 – 1.02 0.545 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 1.02 0.98 – 1.06 0.377 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 0.955 0.864 – 1.05 0.362 427 4268 all phecode
532 Dysphagia Digestive 0.987 0.962 – 1.01 0.315 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 0.99 0.977 – 1 0.0983 28078 261548 all phecode
535.1 Acute gastritis Digestive 0.985 0.928 – 1.05 0.628 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 0.981 0.881 – 1.09 0.72 370 3687 all phecode
535.6 Duodenitis Digestive 0.984 0.961 – 1.01 0.176 7592 75928 all phecode
535.8 Other specified gastritis Digestive 0.995 0.972 – 1.02 0.637 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.998 0.825 – 1.21 0.985 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.992 0.874 – 1.13 0.904 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 1.01 0.973 – 1.04 0.66 3391 33907 all phecode
540 Appendiceal conditions Digestive 0.992 0.956 – 1.03 0.654 3088 30890 all phecode
540.1 Appendicitis Digestive 0.988 0.951 – 1.03 0.516 2895 28963 all phecode
540.11 Acute appendicitis Digestive 0.987 0.948 – 1.03 0.506 2601 26019 all phecode
550 Abdominal hernia Digestive 0.995 0.985 – 1.01 0.361 45429 282640 all phecode
550.1 Inguinal hernia Digestive 0.989 0.973 – 1.01 0.212 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 1 0.987 – 1.01 0.986 26494 238953 all phecode
550.3 Femoral hernia Digestive 0.984 0.908 – 1.07 0.686 651 6504 all phecode
550.4 Umbilical hernia Digestive 1.02 0.987 – 1.06 0.23 3705 37072 all phecode
550.5 Ventral hernia Digestive 0.991 0.956 – 1.03 0.607 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 0.993 0.963 – 1.02 0.659 4444 44442 all phecode
555.1 Regional enteritis Digestive 1 0.954 – 1.05 0.928 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 0.979 0.943 – 1.02 0.248 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 0.983 0.9 – 1.07 0.703 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 1.08 1.01 – 1.15 0.0179 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 1.04 0.962 – 1.12 0.324 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.975 0.865 – 1.1 0.682 299 2987 all phecode
557.1 Celiac disease Digestive 0.943 0.897 – 0.99 0.0178 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 1.01 0.992 – 1.03 0.311 15492 155105 all phecode
559 Ileostomy status Digestive 0.973 0.924 – 1.02 0.295 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.01 0.981 – 1.05 0.407 3936 39337 all phecode
560.1 Paralytic ileus Digestive 1.05 0.958 – 1.14 0.315 523 5231 all phecode
560.2 Impaction of intestine Digestive 1.01 0.889 – 1.14 0.916 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.973 0.905 – 1.04 0.447 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 1 0.965 – 1.04 0.981 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 0.996 0.98 – 1.01 0.662 15772 157686 all phecode
561.1 Diarrhea Digestive 1 0.91 – 1.1 0.975 466 4653 all phecode
561.2 Flatulence Digestive 1.01 0.963 – 1.06 0.62 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 0.997 0.984 – 1.01 0.614 26714 211692 all phecode
562.1 Diverticulosis Digestive 0.997 0.984 – 1.01 0.594 26672 211642 all phecode
563 Constipation Digestive 0.995 0.975 – 1.02 0.615 10314 103140 all phecode
564 Functional digestive disorders Digestive 0.997 0.983 – 1.01 0.702 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 1.01 0.982 – 1.04 0.509 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.01 0.959 – 1.06 0.722 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 0.992 0.975 – 1.01 0.34 15186 151648 all phecode
565 Anal and rectal conditions Digestive 0.993 0.977 – 1.01 0.434 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 0.998 0.974 – 1.02 0.848 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.01 0.94 – 1.07 0.883 929 9293 all phecode
568 Other disorders of peritoneum Digestive 1.03 0.997 – 1.07 0.0759 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.03 0.991 – 1.07 0.145 3101 30987 all phecode
569 Other disorders of intestine Digestive 1.01 0.979 – 1.04 0.505 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.949 0.799 – 1.13 0.549 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 1.06 0.971 – 1.16 0.186 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 1 0.963 – 1.04 1 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.02 0.971 – 1.07 0.421 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.91 0.748 – 1.11 0.344 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 0.98 0.862 – 1.12 0.763 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.987 0.924 – 1.05 0.694 976 9804 all phecode
571.81 Portal hypertension Digestive 0.957 0.875 – 1.05 0.341 528 5285 all phecode
572 Ascites (non malignant) Digestive 1.05 1 – 1.11 0.0505 1544 15454 all phecode
573 Other disorders of liver Digestive 1.03 0.977 – 1.09 0.267 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 0.889 0.713 – 1.11 0.297 96 960 all phecode
573.3 Hepatomegaly Digestive 0.946 0.84 – 1.06 0.355 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 0.942 0.878 – 1.01 0.0893 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 0.995 0.961 – 1.03 0.791 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 0.93 0.807 – 1.07 0.317 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 0.984 0.968 – 1 0.0564 15607 156123 all phecode
574.1 Cholelithiasis Digestive 0.982 0.964 – 0.999 0.04 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.95 0.9 – 1 0.0595 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1 0.972 – 1.03 0.986 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 1.02 0.979 – 1.06 0.346 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.962 0.924 – 1 0.0539 2748 27523 all phecode
575 Other biliary tract disease Digestive 1 0.97 – 1.04 0.879 3867 38724 all phecode
575.1 Cholangitis Digestive 1.01 0.92 – 1.11 0.849 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 0.945 0.876 – 1.02 0.144 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.961 0.873 – 1.06 0.42 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 1.01 0.959 – 1.07 0.651 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 1 0.939 – 1.07 0.962 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.07 0.957 – 1.19 0.245 348 3488 all phecode
577 Diseases of pancreas Digestive 1.01 0.975 – 1.06 0.466 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 1.02 0.975 – 1.07 0.386 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 0.931 0.849 – 1.02 0.127 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 0.993 0.892 – 1.1 0.893 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 1 0.99 – 1.02 0.525 20626 206278 all phecode
578.1 Hematemesis Digestive 0.956 0.913 – 1 0.063 1958 19564 all phecode
578.2 Blood in stool Digestive 0.983 0.944 – 1.02 0.414 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.02 0.998 – 1.03 0.0888 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.994 0.966 – 1.02 0.666 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1 0.951 – 1.06 0.934 1548 15498 all phecode
579.2 Splenomegaly Digestive 0.972 0.879 – 1.07 0.575 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.99 0.941 – 1.04 0.713 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.04 0.983 – 1.09 0.188 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 1.03 0.971 – 1.1 0.303 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1 0.798 – 1.26 0.984 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.791 0.657 – 0.952 0.0131 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.06 0.988 – 1.13 0.105 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.09 0.997 – 1.2 0.0593 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.967 0.847 – 1.1 0.617 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.985 0.866 – 1.12 0.821 253 2529 all phecode
585 Renal failure Genitourinary 1.01 0.987 – 1.04 0.343 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 1.02 0.984 – 1.05 0.34 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 1.01 0.956 – 1.06 0.766 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.01 0.972 – 1.05 0.574 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 1.01 0.917 – 1.1 0.9 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 0.998 0.963 – 1.03 0.899 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.89 0.769 – 1.03 0.122 208 2089 all phecode
586.11 Small kidney Genitourinary 0.915 0.781 – 1.07 0.274 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.01 0.955 – 1.07 0.683 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.03 0.822 – 1.29 0.802 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.02 0.951 – 1.09 0.611 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 0.977 0.875 – 1.09 0.672 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.03 0.832 – 1.28 0.786 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.02 0.847 – 1.22 0.852 116 1158 all phecode
590 Pyelonephritis Genitourinary 1.02 0.963 – 1.08 0.514 1328 13285 all phecode
591 Urinary tract infection Genitourinary 0.993 0.975 – 1.01 0.46 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 0.997 0.96 – 1.03 0.858 2966 29661 all phecode
592.1 Cystitis Genitourinary 0.99 0.953 – 1.03 0.609 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 0.954 0.802 – 1.13 0.595 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 0.968 0.903 – 1.04 0.357 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 1.01 0.889 – 1.15 0.862 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.09 0.941 – 1.27 0.242 165 1662 all phecode
593 Hematuria Genitourinary 0.983 0.967 – 0.999 0.0382 16068 160204 all phecode
594 Urinary calculus Genitourinary 0.978 0.953 – 1 0.0948 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 1.01 0.971 – 1.04 0.697 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 0.906 0.84 – 0.978 0.011 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 1 0.959 – 1.04 1 2401 24024 all phecode
594.8 Renal colic Genitourinary 0.964 0.921 – 1.01 0.12 2050 20500 all phecode
595 Hydronephrosis Genitourinary 0.974 0.929 – 1.02 0.275 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 1 0.982 – 1.02 0.831 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 0.962 0.918 – 1.01 0.11 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 0.995 0.946 – 1.05 0.851 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.01 0.977 – 1.04 0.546 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1 0.969 – 1.04 0.811 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 1.1 0.879 – 1.37 0.416 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 0.969 0.936 – 1 0.0827 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.947 0.841 – 1.07 0.367 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 0.993 0.978 – 1.01 0.35 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 0.901 0.764 – 1.06 0.216 166 1670 all phecode
599.2 Retention of urine Genitourinary 1.02 0.998 – 1.05 0.0765 6718 67168 all phecode
599.3 Dysuria Genitourinary 0.991 0.933 – 1.05 0.781 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 0.99 0.969 – 1.01 0.389 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.01 0.978 – 1.04 0.541 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 0.927 0.755 – 1.14 0.464 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 0.927 0.714 – 1.2 0.565 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 1.04 0.992 – 1.09 0.106 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 1 0.983 – 1.02 0.815 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.986 0.943 – 1.03 0.546 2081 20818 all phecode
601.1 Prostatitis Genitourinary 1.02 0.967 – 1.07 0.504 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 1.03 0.902 – 1.17 0.675 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 1.01 0.946 – 1.08 0.722 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.13 0.876 – 1.45 0.349 59 588 all phecode
601.4 Balanoposthitis Genitourinary 0.932 0.826 – 1.05 0.257 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.959 0.85 – 1.08 0.493 303 3019 all phecode
602 Other disorders of prostate Genitourinary 1.01 0.953 – 1.07 0.786 1341 13408 all phecode
603 Other disorders of testis Genitourinary 0.996 0.953 – 1.04 0.854 2150 21512 all phecode
603.1 Hydrocele Genitourinary 0.985 0.931 – 1.04 0.6 1339 13402 all phecode
604 Disorders of penis Genitourinary 0.997 0.962 – 1.03 0.884 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.974 0.936 – 1.01 0.193 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.08 0.96 – 1.22 0.199 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 1.02 0.98 – 1.06 0.339 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.948 0.825 – 1.09 0.451 214 2138 all phecode
609.1 Infertility, male Genitourinary 1.04 0.81 – 1.33 0.777 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 0.962 0.823 – 1.13 0.632 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 1 0.961 – 1.04 0.93 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 1.01 0.945 – 1.08 0.746 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.1 0.981 – 1.23 0.102 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 0.971 0.862 – 1.1 0.636 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.985 0.932 – 1.04 0.594 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.988 0.913 – 1.07 0.766 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.02 0.97 – 1.07 0.428 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 1.06 0.81 – 1.4 0.657 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 1.02 0.972 – 1.08 0.368 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.979 0.914 – 1.05 0.556 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.975 0.908 – 1.05 0.481 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 1.14 0.906 – 1.44 0.259 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 0.959 0.911 – 1.01 0.107 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 0.931 0.861 – 1.01 0.0747 720 7210 all phecode
613.5 Mastodynia Genitourinary 0.763 0.593 – 0.983 0.036 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 1.02 0.946 – 1.11 0.572 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 1.02 0.912 – 1.14 0.736 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 0.979 0.85 – 1.13 0.769 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.977 0.951 – 1 0.103 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.966 0.927 – 1.01 0.0976 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.987 0.919 – 1.06 0.72 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 0.986 0.756 – 1.28 0.916 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.953 0.863 – 1.05 0.35 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.04 0.93 – 1.16 0.504 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.989 0.874 – 1.12 0.867 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.981 0.942 – 1.02 0.35 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.985 0.931 – 1.04 0.606 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.03 0.937 – 1.14 0.505 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.956 0.886 – 1.03 0.238 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.977 0.865 – 1.1 0.707 274 2737 all phecode
615 Endometriosis Genitourinary 0.981 0.95 – 1.01 0.254 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.08 0.963 – 1.21 0.189 304 3037 all phecode
618 Genital prolapse Genitourinary 1.01 0.992 – 1.03 0.249 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1.01 0.986 – 1.03 0.425 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.01 0.986 – 1.04 0.338 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.02 0.933 – 1.12 0.65 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 0.983 0.907 – 1.06 0.665 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 1 0.98 – 1.02 0.865 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.02 0.942 – 1.1 0.688 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 0.975 0.941 – 1.01 0.176 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.03 0.987 – 1.07 0.194 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.03 0.982 – 1.08 0.218 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.972 0.919 – 1.03 0.33 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 1.05 0.831 – 1.33 0.683 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 0.966 0.908 – 1.03 0.27 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 1 0.982 – 1.02 0.872 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.999 0.976 – 1.02 0.944 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 1 0.967 – 1.04 0.936 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.01 0.952 – 1.07 0.798 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 0.939 0.872 – 1.01 0.0981 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.935 0.817 – 1.07 0.323 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.956 0.864 – 1.06 0.383 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 0.985 0.958 – 1.01 0.26 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1 0.966 – 1.04 0.825 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 1 0.942 – 1.06 0.992 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1 0.987 – 1.02 0.718 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1 0.987 – 1.02 0.628 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.91 0.741 – 1.12 0.368 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.01 0.987 – 1.03 0.439 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 0.981 0.937 – 1.03 0.426 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 1 0.972 – 1.04 0.787 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 0.951 0.905 – 1 0.049 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 1.16 0.994 – 1.35 0.0592 159 1587 all phecode
626.8 Infertility, female Genitourinary 0.988 0.934 – 1.04 0.675 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.01 0.991 – 1.03 0.296 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 1.01 0.987 – 1.03 0.458 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 1.12 0.971 – 1.3 0.118 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 0.986 0.927 – 1.05 0.667 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 1.1 0.985 – 1.24 0.089 310 3097 all phecode
628 Ovarian cyst Genitourinary 0.988 0.959 – 1.02 0.432 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.996 0.967 – 1.03 0.801 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.04 0.981 – 1.11 0.186 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.03 0.92 – 1.15 0.622 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 1 0.954 – 1.05 0.984 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 1 0.934 – 1.08 0.929 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.996 0.939 – 1.06 0.881 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.02 0.974 – 1.06 0.449 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 1.01 0.928 – 1.1 0.853 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.02 0.962 – 1.09 0.464 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 0.892 0.683 – 1.16 0.399 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.982 0.922 – 1.04 0.563 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.08 0.963 – 1.21 0.188 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.839 0.725 – 0.972 0.0196 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.893 0.754 – 1.06 0.189 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.997 0.941 – 1.06 0.914 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.994 0.951 – 1.04 0.79 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.05 0.836 – 1.33 0.655 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.1 0.974 – 1.24 0.126 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.973 0.805 – 1.18 0.778 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.01 0.871 – 1.18 0.88 193 1922 all phecode
650 Normal delivery Pregnancy Complications 1.01 0.968 – 1.06 0.538 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 1.01 0.9 – 1.12 0.923 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.98 0.932 – 1.03 0.436 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.01 0.954 – 1.07 0.758 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.3 1.03 – 1.63 0.0246 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.98 0.949 – 1.01 0.228 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.03 0.849 – 1.24 0.779 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.961 0.919 – 1.01 0.0817 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.98 0.896 – 1.07 0.668 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.984 0.955 – 1.01 0.283 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1 0.961 – 1.04 0.953 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.793 0.662 – 0.949 0.0115 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.971 0.856 – 1.1 0.645 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.954 0.732 – 1.24 0.729 63 624 all phecode
679 Complications of in utero procedures Dermatologic 1.12 0.846 – 1.47 0.437 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 1.01 0.983 – 1.03 0.558 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.907 0.83 – 0.992 0.0324 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.03 0.944 – 1.13 0.492 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.01 0.985 – 1.04 0.394 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.01 0.987 – 1.04 0.307 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.01 0.985 – 1.04 0.358 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.07 0.987 – 1.16 0.0982 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.11 1.05 – 1.17 0.000209 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.01 0.969 – 1.06 0.603 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 1.01 0.927 – 1.1 0.841 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 0.9 0.806 – 1.01 0.0621 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1.1 1.01 – 1.2 0.0269 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.986 0.943 – 1.03 0.545 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.11 0.988 – 1.25 0.0787 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 1.07 0.876 – 1.3 0.515 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.02 0.981 – 1.06 0.323 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.977 0.95 – 1 0.0907 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.856 0.668 – 1.1 0.222 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.812 0.599 – 1.1 0.18 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 0.844 0.692 – 1.03 0.0928 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.93 0.869 – 0.995 0.0347 986 9854 all phecode
694.1 Vitiligo Dermatologic 0.943 0.716 – 1.24 0.677 60 599 all phecode
694.2 Other dyschromia Dermatologic 0.932 0.864 – 1 0.066 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 0.942 0.776 – 1.14 0.543 117 1170 all phecode
695 Erythematous conditions Dermatologic 0.994 0.952 – 1.04 0.764 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 1.11 0.928 – 1.34 0.248 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 1.06 0.898 – 1.26 0.47 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 1.07 0.826 – 1.39 0.609 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.14 0.909 – 1.44 0.25 73 727 all phecode
695.3 Rosacea Dermatologic 1.08 0.963 – 1.21 0.189 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 0.967 0.872 – 1.07 0.533 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.842 0.695 – 1.02 0.0778 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 0.987 0.881 – 1.1 0.819 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 0.989 0.918 – 1.06 0.76 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 0.935 0.817 – 1.07 0.33 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 0.811 0.632 – 1.04 0.0999 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 0.984 0.893 – 1.08 0.749 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 0.955 0.914 – 0.998 0.0405 2252 22509 all phecode
696.4 Psoriasis Dermatologic 0.957 0.916 – 1 0.0555 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 0.973 0.925 – 1.02 0.296 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 0.956 0.883 – 1.03 0.261 706 7052 all phecode
697 Sarcoidosis Dermatologic 1.04 0.951 – 1.13 0.4 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 0.982 0.913 – 1.06 0.631 782 7814 all phecode
700 Corns and callosities Dermatologic 0.97 0.859 – 1.1 0.622 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1 0.974 – 1.03 0.813 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 1.07 0.858 – 1.32 0.566 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.02 0.975 – 1.06 0.429 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.15 0.889 – 1.48 0.293 61 610 all phecode
701.4 Keloid scar Dermatologic 0.936 0.813 – 1.08 0.361 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.03 0.933 – 1.13 0.58 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 0.92 0.749 – 1.13 0.428 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1 0.977 – 1.03 0.728 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 1 0.961 – 1.04 0.96 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 1.01 0.972 – 1.05 0.657 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 1.01 0.903 – 1.12 0.89 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 1.05 0.989 – 1.12 0.107 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 1.03 0.999 – 1.06 0.0615 5267 52727 all phecode
704.1 Alopecia Dermatologic 0.972 0.807 – 1.17 0.765 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.13 0.915 – 1.4 0.255 76 759 all phecode
705 Disorders of sweat glands Dermatologic 0.985 0.86 – 1.13 0.829 228 2287 all phecode
705.3 Hidradenitis Dermatologic 0.958 0.825 – 1.11 0.571 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 1.1 1.02 – 1.19 0.0199 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 1.03 1.01 – 1.06 0.00449 8317 83195 all phecode
706.1 Acne Dermatologic 1.23 0.992 – 1.53 0.059 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 1.02 1 – 1.05 0.0263 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 1.03 0.985 – 1.08 0.192 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 1.03 0.964 – 1.1 0.363 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 1 0.97 – 1.04 0.795 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 1.01 0.924 – 1.11 0.806 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 0.987 0.845 – 1.15 0.868 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1 0.787 – 1.28 0.982 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.998 0.959 – 1.04 0.904 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.04 0.962 – 1.14 0.298 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 1.03 0.942 – 1.12 0.539 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.03 0.886 – 1.19 0.724 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.03 0.931 – 1.14 0.548 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.04 0.946 – 1.15 0.389 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.05 0.939 – 1.17 0.391 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.24 0.998 – 1.54 0.0517 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.14 0.966 – 1.34 0.121 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.13 0.888 – 1.44 0.317 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.992 0.963 – 1.02 0.614 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.989 0.958 – 1.02 0.474 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.97 0.922 – 1.02 0.236 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.976 0.805 – 1.18 0.805 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1 0.923 – 1.09 0.964 618 6177 all phecode
716 Other arthropathies Musculoskeletal 1.01 0.999 – 1.02 0.0762 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.02 0.989 – 1.06 0.19 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.01 0.99 – 1.02 0.442 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.01 0.997 – 1.02 0.168 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.996 0.937 – 1.06 0.899 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 1.01 0.978 – 1.05 0.498 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1 0.981 – 1.03 0.708 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.01 0.983 – 1.04 0.407 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.01 0.865 – 1.17 0.946 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.04 0.938 – 1.16 0.429 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 1.03 1 – 1.05 0.0245 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.992 0.905 – 1.09 0.863 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.03 0.996 – 1.07 0.0835 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 0.976 0.759 – 1.26 0.851 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.04 1.01 – 1.07 0.014 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 1.06 0.967 – 1.16 0.218 517 5173 all phecode
723.1 Torticollis Musculoskeletal 1.05 0.867 – 1.27 0.628 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.03 0.986 – 1.08 0.173 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 0.96 0.866 – 1.06 0.435 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 0.956 0.863 – 1.06 0.395 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.18 0.921 – 1.51 0.191 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.04 0.992 – 1.1 0.0967 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1 0.983 – 1.02 0.986 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 1 0.982 – 1.02 0.77 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 0.972 0.869 – 1.09 0.621 334 3336 all phecode
726.3 Bursitis Musculoskeletal 0.983 0.917 – 1.05 0.622 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.01 0.987 – 1.04 0.39 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.975 0.937 – 1.01 0.208 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 1.12 0.926 – 1.36 0.24 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.01 0.975 – 1.05 0.543 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 1.08 0.993 – 1.17 0.0721 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.991 0.888 – 1.11 0.87 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.03 0.869 – 1.23 0.705 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.02 0.986 – 1.06 0.245 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.06 0.958 – 1.17 0.273 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 1.02 0.985 – 1.05 0.274 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.02 0.981 – 1.05 0.395 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.02 0.989 – 1.04 0.249 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1 0.94 – 1.07 0.905 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 0.984 0.801 – 1.21 0.875 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.973 0.858 – 1.1 0.665 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.972 0.855 – 1.11 0.669 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 0.954 0.866 – 1.05 0.335 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.876 0.755 – 1.02 0.0782 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.07 0.822 – 1.39 0.622 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.999 0.951 – 1.05 0.973 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 0.989 0.878 – 1.11 0.86 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.03 0.944 – 1.13 0.495 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 0.984 0.826 – 1.17 0.851 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.958 0.902 – 1.02 0.156 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 0.87 0.717 – 1.06 0.156 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 1 0.982 – 1.02 0.805 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 1.01 0.877 – 1.17 0.857 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 1.01 0.978 – 1.04 0.662 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.02 0.971 – 1.07 0.465 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 0.991 0.94 – 1.04 0.727 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.01 0.981 – 1.03 0.647 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 1.02 0.973 – 1.08 0.379 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1 0.88 – 1.15 0.945 248 2476 all phecode
737 Curvature of spine Musculoskeletal 0.984 0.925 – 1.05 0.606 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.978 0.918 – 1.04 0.495 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1 0.957 – 1.05 0.895 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.973 0.922 – 1.03 0.308 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 0.986 0.899 – 1.08 0.762 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 1.01 1 – 1.03 0.0348 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.01 0.995 – 1.03 0.167 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.01 0.984 – 1.03 0.643 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 0.989 0.887 – 1.1 0.845 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.958 0.88 – 1.04 0.329 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.02 1 – 1.04 0.0467 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.04 1 – 1.07 0.0425 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 1.09 0.889 – 1.34 0.408 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 1.06 0.981 – 1.15 0.136 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 1.05 0.894 – 1.23 0.564 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 1.05 0.997 – 1.11 0.0664 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 1.18 0.974 – 1.43 0.0905 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 0.768 0.572 – 1.03 0.0782 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.03 0.995 – 1.07 0.0864 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 1.05 0.939 – 1.17 0.397 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.887 0.716 – 1.1 0.27 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.11 1.02 – 1.22 0.0215 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 1.03 0.981 – 1.07 0.263 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.01 0.984 – 1.03 0.551 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 1 0.979 – 1.03 0.739 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 1 0.974 – 1.03 0.928 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 0.996 0.911 – 1.09 0.934 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 1.02 0.927 – 1.11 0.739 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.04 0.972 – 1.12 0.238 815 8144 all phecode
745 Pain in joint Musculoskeletal 0.996 0.973 – 1.02 0.746 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.985 0.947 – 1.02 0.437 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.984 0.945 – 1.03 0.445 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.979 0.897 – 1.07 0.623 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.922 0.804 – 1.06 0.251 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.988 0.942 – 1.04 0.64 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.999 0.857 – 1.17 0.995 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.22 0.924 – 1.6 0.163 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.06 0.943 – 1.2 0.319 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.994 0.92 – 1.08 0.887 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.979 0.874 – 1.1 0.711 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.903 0.777 – 1.05 0.186 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.02 0.92 – 1.14 0.659 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 1.01 0.88 – 1.15 0.93 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.999 0.827 – 1.21 0.989 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.944 0.894 – 0.997 0.0369 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.914 0.843 – 0.991 0.0296 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.946 0.857 – 1.05 0.276 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.88 0.765 – 1.01 0.0766 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.991 0.923 – 1.06 0.804 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 1.02 0.922 – 1.13 0.714 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.992 0.887 – 1.11 0.888 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.944 0.841 – 1.06 0.334 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 1.04 0.917 – 1.19 0.513 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 1.01 0.873 – 1.17 0.905 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.769 0.593 – 0.998 0.0482 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.14 0.957 – 1.37 0.139 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.1 0.876 – 1.39 0.401 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.921 0.756 – 1.12 0.415 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.01 0.91 – 1.11 0.91 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.08 0.938 – 1.24 0.289 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.841 0.706 – 1 0.053 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.808 0.649 – 1.01 0.0557 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.01 0.929 – 1.1 0.824 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 1.05 0.834 – 1.31 0.696 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.02 0.924 – 1.12 0.72 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.15 0.977 – 1.35 0.0924 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.05 0.814 – 1.35 0.717 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.967 0.843 – 1.11 0.637 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.957 0.782 – 1.17 0.668 96 959 all phecode
760 Back pain Symptoms 1.01 0.99 – 1.03 0.327 11126 111353 all phecode
761 Cervicalgia Symptoms 1.01 0.961 – 1.06 0.723 1791 17901 all phecode
764 Sciatica Symptoms 1 0.961 – 1.05 0.909 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.06 0.994 – 1.12 0.0757 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 1.11 1.03 – 1.2 0.00739 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.953 0.889 – 1.02 0.18 870 8687 all phecode
771.1 Swelling of limb Symptoms 1.01 0.984 – 1.04 0.378 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 1.06 0.985 – 1.15 0.115 659 6581 all phecode
773 Pain in limb Symptoms 1 0.975 – 1.03 0.919 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 0.96 0.821 – 1.12 0.614 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.05 1.01 – 1.11 0.0276 1870 18715 all phecode
782.3 Edema Symptoms 1.03 0.977 – 1.08 0.285 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 1.07 0.918 – 1.25 0.385 175 1748 all phecode
783 Fever of unknown origin Symptoms 1.01 0.978 – 1.04 0.509 3911 39105 all phecode
785 Abdominal pain Symptoms 1 0.991 – 1.01 0.753 40080 301686 all phecode
788 Syncope and collapse Symptoms 0.982 0.961 – 1 0.0987 9069 90813 all phecode
789 Nausea and vomiting Symptoms 1 0.983 – 1.02 0.81 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.02 0.867 – 1.2 0.803 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 0.934 0.741 – 1.18 0.566 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 1.02 0.994 – 1.05 0.135 6357 63635 all phecode
791 Gangrene Symptoms 1.08 0.989 – 1.17 0.0867 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.948 0.764 – 1.18 0.627 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.05 0.885 – 1.24 0.584 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 0.974 0.893 – 1.06 0.557 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.964 0.798 – 1.17 0.705 120 1198 all phecode
797 Shock Symptoms 1.15 0.988 – 1.35 0.07 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 1.16 0.954 – 1.4 0.139 102 1020 all phecode
798 Malaise and fatigue Symptoms 1 0.966 – 1.04 0.958 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 1 0.922 – 1.09 0.926 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 1.01 0.987 – 1.04 0.367 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.982 0.935 – 1.03 0.457 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.13 0.977 – 1.32 0.0994 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.07 1.02 – 1.12 0.0023 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 1.04 0.97 – 1.12 0.25 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.03 0.983 – 1.07 0.238 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.04 0.995 – 1.09 0.0788 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 1.03 0.959 – 1.12 0.376 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 1.03 1 – 1.05 0.0309 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.03 0.983 – 1.09 0.201 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.02 0.995 – 1.05 0.106 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.04 0.985 – 1.09 0.162 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 1 0.968 – 1.04 0.849 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1 0.946 – 1.06 0.998 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 0.988 0.918 – 1.06 0.741 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.01 0.957 – 1.07 0.652 1300 12998 all phecode
817 Concussion Injuries & Poisonings 1.01 0.89 – 1.16 0.837 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.06 0.971 – 1.16 0.19 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.03 0.988 – 1.07 0.18 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 1.08 1.03 – 1.14 0.00148 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 0.979 0.936 – 1.02 0.353 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 1.02 1 – 1.03 0.0362 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.07 0.98 – 1.17 0.132 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 0.977 0.89 – 1.07 0.632 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.02 0.989 – 1.05 0.246 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.04 0.881 – 1.23 0.653 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.02 0.929 – 1.12 0.694 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.987 0.94 – 1.04 0.586 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.981 0.925 – 1.04 0.517 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.968 0.933 – 1 0.0821 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.02 0.981 – 1.05 0.361 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1.34 1.05 – 1.7 0.0165 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.01 0.979 – 1.05 0.435 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.971 0.858 – 1.1 0.648 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 1.05 0.912 – 1.22 0.473 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.02 0.984 – 1.06 0.271 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.01 0.884 – 1.16 0.834 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 0.801 0.619 – 1.04 0.0916 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 1 0.971 – 1.04 0.848 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.01 0.77 – 1.34 0.922 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.04 0.837 – 1.3 0.704 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.07 0.92 – 1.24 0.385 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 1.01 0.916 – 1.11 0.893 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 1.12 0.983 – 1.28 0.087 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.11 0.957 – 1.29 0.168 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.1 0.935 – 1.29 0.258 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.03 0.976 – 1.09 0.273 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.02 0.988 – 1.05 0.238 4260 42663 all phecode
916 Contusion Injuries & Poisonings 1.02 0.963 – 1.07 0.552 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.911 0.778 – 1.07 0.247 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.03 0.93 – 1.14 0.582 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.95 0.835 – 1.08 0.439 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.05 1 – 1.09 0.0455 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.11 0.97 – 1.26 0.13 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.03 0.842 – 1.25 0.791 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.94 0.859 – 1.03 0.176 550 5509 all phecode
947 Urticaria Injuries & Poisonings 1.01 0.913 – 1.13 0.782 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 0.928 0.835 – 1.03 0.168 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.945 0.854 – 1.05 0.272 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.01 0.893 – 1.15 0.851 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.987 0.899 – 1.08 0.785 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 0.973 0.74 – 1.28 0.844 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.82 0.633 – 1.06 0.132 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.01 0.99 – 1.02 0.493 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.01 0.991 – 1.02 0.364 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 0.956 0.863 – 1.06 0.389 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.954 0.889 – 1.02 0.197 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.07 0.96 – 1.18 0.232 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.07 0.962 – 1.19 0.209 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.958 0.833 – 1.1 0.551 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.09 0.968 – 1.22 0.157 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.12 0.995 – 1.26 0.0604 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.971 0.946 – 0.997 0.0312 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.02 0.96 – 1.08 0.519 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.08 0.987 – 1.19 0.0912 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.928 0.837 – 1.03 0.156 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.02 0.928 – 1.11 0.732 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.06 0.978 – 1.16 0.15 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 0.981 0.936 – 1.03 0.426 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.924 0.793 – 1.08 0.306 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.992 0.876 – 1.12 0.9 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.973 0.781 – 1.21 0.806 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.29 1.07 – 1.56 0.00657 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.12 0.921 – 1.35 0.265 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.805 0.616 – 1.05 0.113 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.01 0.764 – 1.33 0.966 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.01 0.887 – 1.16 0.85 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 0.991 0.917 – 1.07 0.828 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.925 0.799 – 1.07 0.297 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.1 0.859 – 1.41 0.444 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 0.994 0.812 – 1.22 0.951 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.968 0.795 – 1.18 0.743 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.946 0.757 – 1.18 0.627 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 0.997 0.961 – 1.03 0.874 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 1.01 0.972 – 1.05 0.648 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 1.01 0.972 – 1.05 0.648 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 1.02 0.993 – 1.05 0.155 5538 63928 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.03 0.984 – 1.09 0.184 1663 19453 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.06 0.951 – 1.19 0.283 316 4512 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.04 0.952 – 1.14 0.38 514 6251 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1.05 0.762 – 1.46 0.754 32 412 exclusion phecode
010 Tuberculosis Infectious Diseases 1.02 0.833 – 1.24 0.881 100 1154 exclusion phecode
038 Septicemia Infectious Diseases 1.04 0.991 – 1.08 0.121 2126 29197 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.05 0.952 – 1.16 0.327 415 5900 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.09 0.957 – 1.24 0.196 227 3457 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.04 1.02 – 1.07 0.000645 6955 85937 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.11 1.06 – 1.17 1.66e-05 1679 22196 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.05 0.982 – 1.12 0.164 976 11987 exclusion phecode
041.4 E. coli Infectious Diseases 1.06 1 – 1.11 0.0379 1520 19569 exclusion phecode
053 Herpes zoster Infectious Diseases 1.02 0.889 – 1.16 0.807 225 2821 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.73 0.542 – 0.982 0.0377 57 644 exclusion phecode
054 Herpes simplex Infectious Diseases 1 0.846 – 1.19 0.98 141 1606 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.05 0.936 – 1.17 0.427 323 4477 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.16 0.873 – 1.53 0.312 48 549 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 1.13 0.914 – 1.41 0.254 73 968 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.08 0.909 – 1.29 0.376 132 2012 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 0.876 0.733 – 1.05 0.145 140 2057 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.03 0.899 – 1.17 0.706 224 3107 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.1 0.884 – 1.37 0.387 73 1099 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.1 0.859 – 1.4 0.464 59 878 exclusion phecode
078 Viral warts & HPV Infectious Diseases 1.01 0.934 – 1.09 0.826 706 7578 exclusion phecode
079 Viral infection Infectious Diseases 0.995 0.949 – 1.04 0.843 1923 21181 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.915 0.682 – 1.23 0.555 46 518 exclusion phecode
080 Postoperative infection Infectious Diseases 1.03 0.991 – 1.07 0.133 2675 32311 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.07 1.01 – 1.13 0.014 1363 17494 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.95 0.698 – 1.29 0.746 45 535 exclusion phecode
1000 Burns Injuries & Poisonings 0.984 0.887 – 1.09 0.765 381 4263 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 1.08 1 – 1.15 0.0384 822 8739 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.04 1.01 – 1.08 0.0219 3520 39155 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.03 0.893 – 1.19 0.674 191 2193 exclusion phecode
1005 Other symptoms Injuries & Poisonings 1.02 0.952 – 1.09 0.585 863 10313 exclusion phecode
1006 Crushing injury Injuries & Poisonings 0.949 0.813 – 1.11 0.514 176 1821 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 0.957 0.824 – 1.11 0.567 178 1913 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 0.958 0.887 – 1.03 0.269 707 7313 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 1.03 1 – 1.06 0.0224 5883 62296 exclusion phecode
1010 Other tests Injuries & Poisonings 0.989 0.957 – 1.02 0.527 3788 42750 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.01 0.985 – 1.04 0.381 5585 64404 exclusion phecode
1012 Late effect Injuries & Poisonings 1.12 0.893 – 1.41 0.322 76 764 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.07 0.929 – 1.23 0.351 199 2244 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.15 0.884 – 1.5 0.293 53 489 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 0.979 0.94 – 1.02 0.295 2671 31277 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.01 0.992 – 1.03 0.25 10738 116961 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.11 0.952 – 1.3 0.181 161 1992 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 1.13 0.961 – 1.32 0.143 157 1957 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.975 0.725 – 1.31 0.865 47 532 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.14 0.913 – 1.42 0.249 77 994 exclusion phecode
112 Candidiasis Infectious Diseases 1.04 0.985 – 1.1 0.149 1280 15203 exclusion phecode
117 Mycoses Infectious Diseases 1.09 0.926 – 1.29 0.296 142 1917 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.06 0.858 – 1.31 0.582 85 1129 exclusion phecode
130 Spirochetal infection Infectious Diseases 1 0.765 – 1.31 0.984 54 603 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 1.08 0.804 – 1.46 0.603 44 522 exclusion phecode
134 Helminthiases Infectious Diseases 1.01 0.82 – 1.25 0.898 85 996 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 0.996 0.782 – 1.27 0.972 70 838 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.13 0.945 – 1.34 0.184 124 1464 exclusion phecode
145 Cancer of mouth Neoplasms 0.953 0.864 – 1.05 0.341 440 4516 exclusion phecode
145.2 Cancer of tongue Neoplasms 0.888 0.772 – 1.02 0.0969 217 2145 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 1.13 0.886 – 1.43 0.328 68 791 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 0.923 0.654 – 1.3 0.646 37 369 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.919 0.829 – 1.02 0.111 392 4321 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 0.857 0.729 – 1.01 0.0621 170 1800 exclusion phecode
149.4 Cancer of larynx Neoplasms 0.958 0.811 – 1.13 0.609 140 1718 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 1.06 0.775 – 1.44 0.733 40 382 exclusion phecode
150 Cancer of esophagus Neoplasms 0.914 0.828 – 1.01 0.0754 441 4965 exclusion phecode
151 Cancer of stomach Neoplasms 1.02 0.916 – 1.14 0.689 331 3675 exclusion phecode
153 Colorectal cancer Neoplasms 1.03 0.989 – 1.07 0.167 2982 31087 exclusion phecode
153.2 Colon cancer Neoplasms 1.05 1 – 1.1 0.0368 2015 20964 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.984 0.933 – 1.04 0.562 1419 14778 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.04 0.912 – 1.19 0.551 220 2702 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.06 0.839 – 1.34 0.631 69 1024 exclusion phecode
157 Pancreatic cancer Neoplasms 0.966 0.872 – 1.07 0.508 398 4402 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.01 0.934 – 1.09 0.798 686 7382 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 1 0.969 – 1.04 0.876 3553 37731 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.08 0.909 – 1.28 0.381 130 1326 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.927 0.775 – 1.11 0.408 131 1394 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 0.992 0.83 – 1.19 0.934 122 1346 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 1.21 0.893 – 1.64 0.22 41 409 exclusion phecode
165 Cancer within the respiratory system Neoplasms 1.01 0.957 – 1.06 0.817 1593 18688 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.06 1 – 1.12 0.045 1233 14797 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 1.1 0.973 – 1.23 0.13 295 3027 exclusion phecode
170.1 Bone cancer Neoplasms 1.29 1.04 – 1.6 0.0187 84 899 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1.03 0.901 – 1.18 0.646 225 2294 exclusion phecode
172 Skin cancer Neoplasms 0.989 0.969 – 1.01 0.328 9327 92779 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.961 0.917 – 1.01 0.103 1928 19087 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.965 0.92 – 1.01 0.136 1951 19315 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.99 0.967 – 1.01 0.411 7542 74823 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 1.13 1.03 – 1.25 0.014 406 4415 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.97 0.811 – 1.16 0.742 128 1321 exclusion phecode
174 Breast cancer Neoplasms 1.01 0.989 – 1.03 0.368 9487 97258 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1.01 0.987 – 1.03 0.429 9353 95789 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1.01 0.985 – 1.03 0.556 8789 90219 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.06 0.862 – 1.3 0.585 93 905 exclusion phecode
175 Acquired absence of breast Neoplasms 0.997 0.949 – 1.05 0.892 1768 18613 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 0.992 0.944 – 1.04 0.747 1779 18031 exclusion phecode
180.1 Cervical cancer Neoplasms 1.05 0.911 – 1.2 0.515 214 2176 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.974 0.926 – 1.03 0.316 1703 17213 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.986 0.919 – 1.06 0.699 847 9520 exclusion phecode
184 Cancer of other female genital organs Neoplasms 0.979 0.918 – 1.04 0.526 1010 10505 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.965 0.893 – 1.04 0.375 715 7284 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.958 0.885 – 1.04 0.29 693 7046 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.95 0.826 – 1.09 0.476 219 2371 exclusion phecode
185 Cancer of prostate Neoplasms 1.03 0.994 – 1.06 0.106 3690 35865 exclusion phecode
187 Cancer of other male genital organs Neoplasms 1.05 0.941 – 1.18 0.363 304 3153 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.35 0.999 – 1.81 0.0511 40 438 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 1.03 0.898 – 1.19 0.659 199 2112 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.874 0.689 – 1.11 0.266 75 735 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.05 1 – 1.09 0.043 2136 27012 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.11 1 – 1.22 0.0395 403 7221 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.1 1 – 1.22 0.0477 383 6951 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.1 0.78 – 1.56 0.577 31 434 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.02 0.964 – 1.08 0.521 1356 15398 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.01 0.952 – 1.07 0.759 1195 13676 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.999 0.774 – 1.29 0.991 58 938 exclusion phecode
190 Cancer of eye Neoplasms 0.882 0.728 – 1.07 0.2 122 1233 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.928 0.843 – 1.02 0.132 471 4848 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.95 0.855 – 1.06 0.346 389 3944 exclusion phecode
191.11 Cancer of brain Neoplasms 0.955 0.856 – 1.07 0.414 362 3669 exclusion phecode
193 Thyroid cancer Neoplasms 1.17 1.03 – 1.33 0.0166 234 2652 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 0.909 0.691 – 1.2 0.496 58 701 exclusion phecode
195 Cancer, suspected or other Neoplasms 1 0.981 – 1.02 0.978 11114 116438 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 0.997 0.978 – 1.02 0.788 10621 111911 exclusion phecode
197 Chemotherapy Neoplasms 1.01 0.997 – 1.03 0.104 14014 156042 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.02 0.998 – 1.05 0.0652 6170 67750 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.03 0.998 – 1.07 0.0691 3642 38998 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.992 0.939 – 1.05 0.764 1380 15988 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.01 0.952 – 1.08 0.649 1009 11039 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.03 0.981 – 1.08 0.229 1657 18449 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.985 0.901 – 1.08 0.739 527 6027 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.05 0.993 – 1.11 0.0881 1291 14889 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.83 0.683 – 1.01 0.0615 119 1353 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.04 0.974 – 1.12 0.227 841 10306 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.1 0.814 – 1.48 0.536 39 706 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.11 1.02 – 1.22 0.0174 480 6747 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.19 1.03 – 1.38 0.0223 162 2584 exclusion phecode
201 Hodgkin's disease Neoplasms 0.942 0.801 – 1.11 0.473 160 1976 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.05 0.992 – 1.11 0.0963 1288 15846 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.05 0.991 – 1.12 0.0937 1012 12512 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.17 1.03 – 1.33 0.0193 220 2507 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.1 0.985 – 1.22 0.0915 328 4022 exclusion phecode
204 Leukemia Neoplasms 1.05 0.979 – 1.12 0.184 926 11320 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 1.08 0.963 – 1.2 0.198 317 3872 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.04 0.726 – 1.48 0.837 34 413 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 1.08 0.958 – 1.22 0.209 270 3393 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.07 0.952 – 1.21 0.245 271 3228 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 1.09 0.939 – 1.26 0.265 182 2296 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.15 0.946 – 1.4 0.161 103 1010 exclusion phecode
204.4 Multiple myeloma Neoplasms 0.957 0.848 – 1.08 0.48 287 3744 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1.01 0.987 – 1.02 0.572 12795 134394 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.981 0.907 – 1.06 0.631 681 7213 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.05 1.01 – 1.09 0.00477 3571 37441 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 1.01 0.885 – 1.16 0.867 234 2505 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 0.998 0.874 – 1.14 0.981 244 2393 exclusion phecode
214 Lipoma Neoplasms 1.01 0.98 – 1.04 0.49 4392 45251 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.02 0.983 – 1.05 0.323 3277 33835 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.1 1.02 – 1.18 0.00822 820 8233 exclusion phecode
216 Benign neoplasm of skin Neoplasms 1 0.976 – 1.03 0.809 5724 57581 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.01 0.913 – 1.11 0.888 435 4529 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 1.01 0.91 – 1.11 0.921 409 4246 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.989 0.966 – 1.01 0.353 8074 81251 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.988 0.966 – 1.01 0.302 8240 82633 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.923 0.813 – 1.05 0.216 269 2832 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.997 0.937 – 1.06 0.926 1120 11458 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.89 0.759 – 1.04 0.153 173 1750 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 1.34 1.1 – 1.63 0.00398 94 1038 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.21 1 – 1.46 0.0484 100 1152 exclusion phecode
224 Benign neoplasm of eye Neoplasms 1.24 1 – 1.54 0.0492 78 954 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.42 1.04 – 1.94 0.0263 37 458 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.932 0.853 – 1.02 0.116 563 5999 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.947 0.865 – 1.04 0.235 528 5694 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.917 0.664 – 1.27 0.599 43 455 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.899 0.772 – 1.05 0.169 196 2039 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.05 0.963 – 1.14 0.272 548 6287 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.11 0.918 – 1.34 0.284 106 1354 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.06 0.935 – 1.21 0.347 237 2662 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.03 0.895 – 1.19 0.655 204 2262 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.935 0.879 – 0.995 0.0338 1141 11659 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.02 0.976 – 1.07 0.341 1842 18187 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.1 0.999 – 1.22 0.052 414 4535 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.974 0.905 – 1.05 0.492 779 8411 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.09 0.979 – 1.22 0.114 357 3598 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.899 0.814 – 0.992 0.0334 451 5090 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.04 0.975 – 1.1 0.255 1162 13999 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 1.01 0.904 – 1.13 0.839 327 3632 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.1 0.862 – 1.41 0.435 57 715 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.999 0.807 – 1.24 0.996 95 1059 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.03 1 – 1.05 0.0155 9219 108660 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.07 0.993 – 1.16 0.0739 700 8273 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.909 0.693 – 1.19 0.492 60 769 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.02 1 – 1.05 0.031 8765 103937 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.903 0.781 – 1.04 0.171 201 2279 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.919 0.78 – 1.08 0.318 153 1716 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.918 0.776 – 1.09 0.32 145 1639 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.03 0.906 – 1.17 0.672 260 3014 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.02 0.997 – 1.04 0.0937 10925 131077 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.969 0.92 – 1.02 0.249 1489 19737 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.821 0.684 – 0.986 0.0343 140 1800 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.99 0.565 – 1.73 0.971 8 556 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.957 0.836 – 1.09 0.519 222 3357 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 0.901 0.684 – 1.19 0.456 51 1141 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.02 0.996 – 1.04 0.113 9579 118577 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1 0.776 – 1.29 0.997 61 768 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.24 0.869 – 1.76 0.239 25 1338 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.02 0.921 – 1.12 0.738 397 6711 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.02 0.876 – 1.19 0.79 164 3447 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 0.966 0.871 – 1.07 0.51 400 4888 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.985 0.842 – 1.15 0.845 172 1858 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.966 0.842 – 1.11 0.614 228 3014 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.956 0.774 – 1.18 0.678 104 1107 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.934 0.781 – 1.12 0.454 124 2404 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.988 0.91 – 1.07 0.775 596 9087 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 0.906 0.822 – 0.998 0.0447 451 6676 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.11 1.01 – 1.22 0.0294 461 6281 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.07 0.972 – 1.18 0.161 417 5639 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.27 0.998 – 1.62 0.0516 59 1003 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.03 0.935 – 1.14 0.531 413 4880 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.07 0.892 – 1.28 0.473 122 1392 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.34 1.05 – 1.7 0.0179 61 699 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.974 0.825 – 1.15 0.761 143 1869 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.657 0.471 – 0.915 0.0131 47 715 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.12 0.933 – 1.35 0.221 107 1033 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.967 0.863 – 1.08 0.554 337 4714 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.14 0.924 – 1.4 0.224 90 1352 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.06 0.806 – 1.4 0.67 52 805 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.22 0.886 – 1.69 0.221 38 549 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.951 0.816 – 1.11 0.516 185 2651 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.952 0.817 – 1.11 0.524 185 2645 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 1.02 0.881 – 1.18 0.782 204 2141 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.992 0.846 – 1.16 0.916 174 1876 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1.02 0.828 – 1.26 0.838 87 1131 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.03 0.829 – 1.29 0.766 80 1064 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.946 0.727 – 1.23 0.678 55 752 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 0.914 0.741 – 1.13 0.396 102 1134 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.871 0.721 – 1.05 0.15 117 1414 exclusion phecode
260.1 Cachexia Endocrine/metabolic 0.983 0.67 – 1.44 0.929 27 340 exclusion phecode
260.6 Anorexia Endocrine/metabolic 0.968 0.884 – 1.06 0.488 494 5856 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.02 0.944 – 1.1 0.622 692 8706 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.03 0.938 – 1.14 0.515 440 5454 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.04 0.915 – 1.17 0.577 258 3312 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.06 0.775 – 1.46 0.698 36 575 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 0.88 0.742 – 1.04 0.142 152 1775 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.08 0.921 – 1.27 0.343 158 2372 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.1 0.945 – 1.27 0.222 160 2051 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.12 0.955 – 1.32 0.161 134 1749 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.15 0.952 – 1.39 0.148 94 1263 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 0.978 0.753 – 1.27 0.871 55 764 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.999 0.723 – 1.38 0.996 36 475 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.13 0.931 – 1.37 0.216 109 1184 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.1 0.897 – 1.35 0.357 99 1039 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.01 0.994 – 1.02 0.229 20417 170572 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.01 0.994 – 1.02 0.238 20374 170389 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.01 0.996 – 1.03 0.14 18889 164486 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.971 0.698 – 1.35 0.861 38 411 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.04 0.842 – 1.29 0.692 84 1154 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.17 0.981 – 1.4 0.0806 118 1442 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.07 1.02 – 1.13 0.00595 1596 24798 exclusion phecode
274.1 Gout Endocrine/metabolic 1.06 1 – 1.12 0.0375 1237 20817 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.08 0.818 – 1.41 0.603 51 735 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.13 1.02 – 1.25 0.0204 384 4360 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.14 1.02 – 1.26 0.0178 356 3988 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.09 1.03 – 1.15 0.00433 1172 14742 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 1.07 0.972 – 1.18 0.162 423 4588 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.15 1 – 1.32 0.0459 200 2573 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.1 1.01 – 1.19 0.0212 610 8470 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.03 0.839 – 1.26 0.792 100 1209 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.04 1 – 1.07 0.037 3665 50343 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.06 1.02 – 1.11 0.00464 2110 28095 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.16 0.976 – 1.38 0.0923 121 1585 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.04 0.979 – 1.11 0.204 1071 12445 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.11 0.997 – 1.24 0.0564 311 6533 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.08 1.01 – 1.16 0.0317 773 10104 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.983 0.896 – 1.08 0.724 470 7952 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.02 0.928 – 1.13 0.661 420 7243 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 0.744 0.55 – 1.01 0.0544 52 746 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1 0.949 – 1.06 0.964 1409 19646 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.22 1.05 – 1.42 0.0105 151 3022 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 0.886 0.709 – 1.11 0.287 88 971 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.07 0.976 – 1.16 0.157 517 6497 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.976 0.858 – 1.11 0.713 238 2573 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.02 0.857 – 1.22 0.805 132 1611 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.15 0.787 – 1.69 0.467 26 367 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.09 1.06 – 1.12 1.26e-10 5600 79880 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.09 1.06 – 1.12 8.29e-11 5501 78655 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 1 0.781 – 1.29 0.987 61 686 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.18 0.851 – 1.63 0.322 32 510 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.06 0.901 – 1.25 0.466 144 1853 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.06 0.886 – 1.26 0.535 121 1545 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.07 0.849 – 1.34 0.573 77 1012 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1 0.854 – 1.17 0.989 164 1594 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.02 0.991 – 1.05 0.18 4717 56023 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.02 0.987 – 1.05 0.257 4497 53665 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.01 0.901 – 1.13 0.855 322 3555 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.05 0.97 – 1.14 0.22 613 8034 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.05 0.967 – 1.14 0.247 593 7703 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.04 0.947 – 1.15 0.394 430 5434 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.17 0.963 – 1.42 0.114 103 1327 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 0.987 0.791 – 1.23 0.907 80 1277 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.2 0.811 – 1.79 0.357 23 369 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 0.953 0.76 – 1.19 0.675 77 1087 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 0.932 0.666 – 1.3 0.683 33 406 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 0.974 0.712 – 1.33 0.869 42 618 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.03 0.801 – 1.33 0.808 59 972 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.933 0.692 – 1.26 0.647 45 730 exclusion phecode
284 Aplastic anemia Hematopoietic 1.18 1.03 – 1.35 0.0148 200 3051 exclusion phecode
285 Other anemias Hematopoietic 1.03 1 – 1.05 0.0363 7059 87513 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.962 0.829 – 1.12 0.608 185 2064 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.14 1.02 – 1.28 0.0265 268 4887 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.15 1.02 – 1.31 0.0243 235 2923 exclusion phecode
286 Coagulation defects Hematopoietic 0.966 0.885 – 1.05 0.434 557 6766 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.905 0.802 – 1.02 0.102 317 3459 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.839 0.646 – 1.09 0.19 74 734 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.912 0.787 – 1.06 0.224 201 2233 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 0.947 0.688 – 1.3 0.737 38 460 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.45 1.04 – 2.03 0.0285 29 569 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.982 0.856 – 1.13 0.799 218 2823 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.08 1.01 – 1.16 0.0191 868 11543 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.02 0.818 – 1.28 0.841 80 916 exclusion phecode
287.2 Allergic purpura Hematopoietic 1.06 0.768 – 1.47 0.72 30 395 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.06 0.991 – 1.14 0.0868 812 10830 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 0.974 0.847 – 1.12 0.708 214 2939 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.999 0.705 – 1.42 0.997 32 507 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.05 1 – 1.09 0.0296 2279 27246 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.04 0.994 – 1.09 0.0898 1930 22983 exclusion phecode
288.11 Neutropenia Hematopoietic 1.04 0.992 – 1.09 0.105 1937 23042 exclusion phecode
288.3 Eosinophilia Hematopoietic 1.32 0.982 – 1.78 0.0659 40 499 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.08 0.982 – 1.18 0.117 474 6221 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.997 0.851 – 1.17 0.967 164 2167 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.04 0.984 – 1.09 0.179 1575 18736 exclusion phecode
289.5 Diseases of spleen Hematopoietic 0.96 0.852 – 1.08 0.502 291 3627 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.08 0.915 – 1.27 0.365 133 2006 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.27 0.928 – 1.73 0.135 38 649 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.968 0.907 – 1.03 0.314 1010 12458 exclusion phecode
290.1 Dementias Mental Disorders 0.98 0.897 – 1.07 0.643 540 6269 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 1 0.883 – 1.14 0.954 252 2750 exclusion phecode
290.16 Vascular dementia Mental Disorders 0.959 0.787 – 1.17 0.674 99 1219 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.895 0.797 – 1 0.0598 328 4252 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.08 0.807 – 1.44 0.611 42 558 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.967 0.881 – 1.06 0.47 499 6087 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.05 0.849 – 1.29 0.663 95 1045 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.893 0.758 – 1.05 0.178 163 1978 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.02 0.899 – 1.16 0.755 255 3192 exclusion phecode
292 Neurological disorders Mental Disorders 1.03 0.996 – 1.08 0.0807 2712 31905 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.02 0.954 – 1.09 0.576 906 10596 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.939 0.766 – 1.15 0.55 99 1299 exclusion phecode
292.3 Memory loss Mental Disorders 1.01 0.922 – 1.11 0.804 469 4916 exclusion phecode
292.4 Altered mental status Mental Disorders 1.04 0.978 – 1.1 0.236 1211 14671 exclusion phecode
292.6 Hallucinations Mental Disorders 1.15 0.992 – 1.34 0.0641 171 2166 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.03 0.974 – 1.08 0.324 1419 15198 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.982 0.903 – 1.07 0.673 605 6623 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.974 0.887 – 1.07 0.575 493 6382 exclusion phecode
295.1 Schizophrenia Mental Disorders 1 0.894 – 1.12 0.996 326 4364 exclusion phecode
295.2 Paranoid disorders Mental Disorders 1.02 0.843 – 1.23 0.84 111 1363 exclusion phecode
295.3 Psychosis Mental Disorders 0.864 0.699 – 1.07 0.174 101 1317 exclusion phecode
296 Mood disorders Mental Disorders 1.04 1.02 – 1.07 0.000304 8082 94942 exclusion phecode
296.1 Bipolar Mental Disorders 1.05 0.965 – 1.13 0.278 632 8089 exclusion phecode
296.2 Depression Mental Disorders 1.04 1.02 – 1.07 0.00041 7697 90087 exclusion phecode
296.22 Major depressive disorder Mental Disorders 1.01 0.881 – 1.15 0.902 228 2742 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.913 0.79 – 1.05 0.213 208 2413 exclusion phecode
300 Anxiety disorders Mental Disorders 1.01 0.984 – 1.04 0.37 4624 51851 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.02 0.984 – 1.05 0.342 4282 47836 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 0.943 0.775 – 1.15 0.556 109 1153 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.05 0.956 – 1.15 0.311 474 5403 exclusion phecode
300.13 Phobia Mental Disorders 1.05 0.939 – 1.17 0.392 326 3766 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.818 0.655 – 1.02 0.0758 97 1080 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.25 0.914 – 1.72 0.161 37 419 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.05 0.847 – 1.3 0.653 86 965 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.12 0.889 – 1.4 0.345 80 891 exclusion phecode
301 Personality disorders Mental Disorders 1.14 0.99 – 1.31 0.0687 203 2700 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.24 0.989 – 1.55 0.0624 74 1010 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 1.04 0.89 – 1.22 0.604 162 1890 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.07 0.957 – 1.2 0.232 327 3543 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 1.05 0.919 – 1.19 0.499 252 2625 exclusion phecode
303.4 Somatoform disorder Mental Disorders 1.03 0.826 – 1.29 0.79 82 960 exclusion phecode
304 Adjustment reaction Mental Disorders 0.951 0.819 – 1.1 0.51 202 2288 exclusion phecode
305.2 Eating disorder Mental Disorders 1.01 0.794 – 1.29 0.935 73 763 exclusion phecode
306 Other mental disorder Mental Disorders 1.02 1.01 – 1.04 0.0096 17030 167354 exclusion phecode
306.9 Tension headache Mental Disorders 1.04 0.905 – 1.19 0.582 218 2489 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 1 0.768 – 1.31 0.984 54 593 exclusion phecode
313.3 Autism Mental Disorders 1.22 0.907 – 1.65 0.187 39 409 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.02 0.889 – 1.18 0.738 200 2513 exclusion phecode
315.1 Learning disorder Mental Disorders 0.979 0.784 – 1.22 0.854 83 1248 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.982 0.736 – 1.31 0.904 50 615 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.01 0.977 – 1.05 0.508 3375 39026 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.07 0.761 – 1.51 0.692 31 449 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.01 0.984 – 1.03 0.581 8591 92459 exclusion phecode
317.1 Alcoholism Mental Disorders 1 0.976 – 1.03 0.881 6050 64215 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.01 0.923 – 1.11 0.785 450 6050 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.04 1.02 – 1.06 8.26e-05 11090 136722 exclusion phecode
320 Meningitis Neurological 1.02 0.907 – 1.14 0.759 314 3432 exclusion phecode
323 Encephalitis Neurological 1.06 0.933 – 1.21 0.365 242 2561 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 1.15 0.903 – 1.47 0.252 62 590 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.17 1.01 – 1.36 0.0312 186 2017 exclusion phecode
327 Sleep disorders Neurological 1.1 1.02 – 1.18 0.0102 753 8299 exclusion phecode
327.3 Sleep apnea Neurological 1.04 0.998 – 1.08 0.0661 2509 31613 exclusion phecode
327.4 Insomnia Neurological 1.08 0.895 – 1.31 0.415 106 1206 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.16 0.948 – 1.43 0.149 89 1012 exclusion phecode
331 Other cerebral degenerations Neurological 1.02 0.939 – 1.1 0.698 688 7941 exclusion phecode
331.1 Hydrocephalus Neurological 0.946 0.841 – 1.06 0.355 320 3620 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.11 0.976 – 1.26 0.112 245 2859 exclusion phecode
332 Parkinson's disease Neurological 1.05 0.978 – 1.14 0.171 696 7283 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.07 0.982 – 1.16 0.125 563 6369 exclusion phecode
333.1 Essential tremor Neurological 1.17 0.982 – 1.4 0.0778 119 1443 exclusion phecode
333.2 Myoclonus Neurological 1.07 0.828 – 1.37 0.623 65 700 exclusion phecode
333.4 Torsion dystonia Neurological 0.914 0.777 – 1.07 0.272 169 1872 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.01 0.949 – 1.07 0.791 1142 12828 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.1 0.861 – 1.41 0.437 65 836 exclusion phecode
334.2 Anterior horn cell disease Neurological 1.16 0.992 – 1.36 0.0632 159 1626 exclusion phecode
335 Multiple sclerosis Neurological 0.997 0.934 – 1.06 0.933 1001 10396 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.04 0.89 – 1.22 0.606 157 1874 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 0.843 0.6 – 1.19 0.328 36 467 exclusion phecode
338 Pain Neurological 1.1 1 – 1.21 0.0418 465 5734 exclusion phecode
338.1 Acute pain Neurological 1.11 0.973 – 1.27 0.122 226 2898 exclusion phecode
338.2 Chronic pain Neurological 1.07 0.945 – 1.22 0.276 242 2934 exclusion phecode
339 Other headache syndromes Neurological 1.02 0.992 – 1.05 0.17 5457 59083 exclusion phecode
340 Migraine Neurological 0.984 0.94 – 1.03 0.488 2104 22427 exclusion phecode
340.1 Migrain with aura Neurological 0.941 0.796 – 1.11 0.477 154 1692 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.966 0.832 – 1.12 0.656 196 1993 exclusion phecode
342 Hemiplegia Neurological 1.06 0.985 – 1.13 0.123 811 10529 exclusion phecode
343 Infantile cerebral palsy Neurological 0.835 0.676 – 1.03 0.0932 101 1092 exclusion phecode
344 Other paralytic syndromes Neurological 1.06 0.956 – 1.16 0.286 415 4841 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1 0.966 – 1.04 0.998 3449 36984 exclusion phecode
345.1 Epilepsy Neurological 0.979 0.899 – 1.07 0.622 600 6422 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.05 0.934 – 1.17 0.436 313 3237 exclusion phecode
345.12 Partial epilepsy Neurological 0.979 0.846 – 1.13 0.776 200 2113 exclusion phecode
345.3 Convulsions Neurological 0.989 0.939 – 1.04 0.685 1513 16471 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.06 0.868 – 1.3 0.555 91 1064 exclusion phecode
348 Other conditions of brain Neurological 1.05 0.954 – 1.15 0.337 469 5731 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.03 0.881 – 1.21 0.694 159 2021 exclusion phecode
348.4 Cerebral cysts Neurological 1.15 0.938 – 1.41 0.181 97 1023 exclusion phecode
348.7 Coma Neurological 1.03 0.905 – 1.17 0.669 244 2540 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.04 0.879 – 1.23 0.659 147 1803 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 0.936 0.825 – 1.06 0.302 266 2780 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.04 0.915 – 1.19 0.521 221 2482 exclusion phecode
350 Abnormal movement Neurological 1.06 1.01 – 1.11 0.0288 1558 18808 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.04 0.952 – 1.13 0.394 540 6480 exclusion phecode
350.2 Abnormality of gait Neurological 1.05 0.983 – 1.12 0.142 884 10945 exclusion phecode
350.3 Lack of coordination Neurological 1.09 0.955 – 1.24 0.203 223 2634 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.995 0.723 – 1.37 0.976 39 397 exclusion phecode
351 Other peripheral nerve disorders Neurological 1 0.978 – 1.02 0.971 8509 92624 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.03 0.965 – 1.1 0.355 903 9985 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.993 0.885 – 1.11 0.903 319 3438 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.01 0.923 – 1.1 0.883 565 6376 exclusion phecode
353 Nerve root and plexus disorders Neurological 1.03 0.956 – 1.12 0.413 692 8200 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.897 0.71 – 1.13 0.362 79 883 exclusion phecode
353.2 Nerve root lesions Neurological 1.11 0.812 – 1.53 0.505 36 413 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.23 1.01 – 1.5 0.0362 93 1075 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.17 1.09 – 1.26 1e-05 759 9463 exclusion phecode
358 Myoneural disorders Neurological 1.06 0.881 – 1.27 0.541 113 1447 exclusion phecode
358.1 Myasthenia gravis Neurological 1.1 0.906 – 1.33 0.344 105 1336 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 1.12 0.987 – 1.27 0.0804 245 3358 exclusion phecode
359.1 Muscular dystrophies Neurological 0.988 0.768 – 1.27 0.926 61 888 exclusion phecode
359.2 Myopathy Neurological 1.17 1.01 – 1.34 0.0314 190 2586 exclusion phecode
360 Disorders of the globe Sense Organs 0.944 0.821 – 1.08 0.413 226 2287 exclusion phecode
360.2 Progressive myopia Sense Organs 1 0.855 – 1.17 0.997 167 1721 exclusion phecode
361 Retinal detachments and defects Sense Organs 1.02 0.982 – 1.07 0.264 2307 22703 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 1.02 0.96 – 1.09 0.466 980 9779 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.861 0.619 – 1.2 0.372 40 490 exclusion phecode
362 Other retinal disorders Sense Organs 1.05 1.01 – 1.09 0.0271 2379 25973 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.06 1.01 – 1.12 0.0229 1374 14566 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.06 1.01 – 1.12 0.0247 1372 14540 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.13 0.931 – 1.36 0.221 106 1132 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1.1 0.871 – 1.38 0.428 76 683 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.1 1 – 1.21 0.0397 475 5694 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.953 0.794 – 1.14 0.605 126 1302 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.772 0.582 – 1.02 0.0724 61 584 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.945 0.754 – 1.19 0.625 79 801 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1 0.82 – 1.23 0.975 104 1221 exclusion phecode
363.3 Chorioretinal scars Sense Organs 1.1 0.798 – 1.53 0.548 34 506 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.991 0.899 – 1.09 0.856 440 4556 exclusion phecode
364.1 Corneal opacity Sense Organs 1.04 0.8 – 1.35 0.78 58 650 exclusion phecode
364.2 Corneal edema Sense Organs 0.985 0.722 – 1.34 0.925 43 547 exclusion phecode
364.4 Corneal degenerations Sense Organs 1.13 0.956 – 1.33 0.153 149 1459 exclusion phecode
364.41 Keratoconus Sense Organs 1.05 0.823 – 1.33 0.713 66 667 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.914 0.763 – 1.09 0.329 136 1407 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.928 0.723 – 1.19 0.558 69 706 exclusion phecode
365 Glaucoma Sense Organs 1.01 0.975 – 1.05 0.516 2838 29671 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 1 0.929 – 1.09 0.921 674 6777 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 1.01 0.933 – 1.09 0.834 670 6746 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.994 0.905 – 1.09 0.901 477 4805 exclusion phecode
366 Cataract Sense Organs 1.01 0.996 – 1.03 0.136 12277 115766 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 0.928 0.682 – 1.26 0.635 42 517 exclusion phecode
366.2 Senile cataract Sense Organs 1.02 0.988 – 1.05 0.262 5021 54573 exclusion phecode
366.3 Traumatic cataract Sense Organs 1.18 0.943 – 1.48 0.146 69 681 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 1 0.953 – 1.06 0.896 1610 16847 exclusion phecode
367.1 Myopia Sense Organs 1.02 0.949 – 1.09 0.633 880 8778 exclusion phecode
367.2 Astigmatism Sense Organs 0.962 0.8 – 1.16 0.68 124 1340 exclusion phecode
367.8 Hypermetropia Sense Organs 1.03 0.875 – 1.21 0.741 162 1737 exclusion phecode
367.9 Blindness and low vision Sense Organs 0.993 0.9 – 1.1 0.889 439 4993 exclusion phecode
368 Visual disturbances Sense Organs 1.06 1.01 – 1.1 0.0226 1896 21389 exclusion phecode
368.1 Amblyopia Sense Organs 1 0.894 – 1.12 0.983 320 3683 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 0.989 0.899 – 1.09 0.815 454 5275 exclusion phecode
368.3 Anisometropia Sense Organs 1.1 0.91 – 1.33 0.32 103 1123 exclusion phecode
368.4 Visual field defects Sense Organs 1.08 0.947 – 1.24 0.24 209 2315 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 1.16 1.05 – 1.28 0.00352 395 4538 exclusion phecode
369 Infection of the eye Sense Organs 1.06 0.954 – 1.19 0.264 353 4013 exclusion phecode
369.2 Eye infection, viral Sense Organs 0.983 0.775 – 1.25 0.89 72 887 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 1.03 0.86 – 1.22 0.778 131 1554 exclusion phecode
370 Keratitis Sense Organs 1.01 0.868 – 1.17 0.936 190 2088 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.924 0.749 – 1.14 0.457 97 1021 exclusion phecode
371 Inflammation of the eye Sense Organs 1.03 0.986 – 1.08 0.19 2192 22200 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.1 0.983 – 1.23 0.0985 307 3471 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 1.01 0.962 – 1.06 0.684 1752 17237 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.05 0.961 – 1.14 0.292 529 5408 exclusion phecode
374 Other disorders of eyelids Sense Organs 1.01 0.974 – 1.04 0.71 3803 40161 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.979 0.903 – 1.06 0.598 641 6965 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.984 0.928 – 1.04 0.598 1222 12800 exclusion phecode
375 Disorders of lacrimal system Sense Organs 1.01 0.961 – 1.07 0.654 1523 15626 exclusion phecode
375.2 Epiphora Sense Organs 1.02 0.943 – 1.11 0.593 636 6274 exclusion phecode
376 Disorders of the orbit Sense Organs 0.892 0.671 – 1.19 0.434 52 610 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.918 0.799 – 1.05 0.225 228 2651 exclusion phecode
377.1 Optic atrophy Sense Organs 0.92 0.657 – 1.29 0.626 34 417 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.998 0.803 – 1.24 0.988 87 959 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.961 0.898 – 1.03 0.24 958 10370 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.939 0.865 – 1.02 0.129 651 6823 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.02 0.856 – 1.23 0.791 125 1501 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.07 0.914 – 1.25 0.409 171 1962 exclusion phecode
379 Other disorders of eye Sense Organs 0.996 0.955 – 1.04 0.834 2311 25287 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 1.02 0.952 – 1.09 0.588 875 9435 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.985 0.926 – 1.05 0.624 1086 12029 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.01 0.766 – 1.34 0.918 49 522 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.06 0.937 – 1.19 0.365 262 2833 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.94 0.769 – 1.15 0.544 102 1236 exclusion phecode
380 Disorders of external ear Sense Organs 1.01 0.915 – 1.11 0.895 448 4445 exclusion phecode
380.1 Otitis externa Sense Organs 1.03 0.921 – 1.15 0.598 342 3761 exclusion phecode
380.4 Impacted cerumen Sense Organs 1.02 0.903 – 1.16 0.715 250 2575 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.969 0.917 – 1.02 0.256 1414 15684 exclusion phecode
381.1 Otitis media Sense Organs 0.964 0.907 – 1.02 0.232 1156 12856 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 0.975 0.894 – 1.06 0.571 553 6278 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.955 0.801 – 1.14 0.609 135 1457 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 1.14 0.943 – 1.37 0.181 113 1243 exclusion phecode
381.9 Otorrhea Sense Organs 0.885 0.758 – 1.03 0.124 185 2030 exclusion phecode
382 Otalgia Sense Organs 1.03 0.9 – 1.19 0.643 219 2306 exclusion phecode
383 Otosclerosis Sense Organs 1.01 0.885 – 1.16 0.871 232 2353 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 0.98 0.916 – 1.05 0.569 919 9595 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 0.991 0.918 – 1.07 0.821 732 7653 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.03 0.941 – 1.12 0.553 527 5736 exclusion phecode
385.3 Cholesteatoma Sense Organs 1.01 0.908 – 1.11 0.91 400 4423 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.04 0.889 – 1.21 0.645 170 1806 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.08 1.02 – 1.15 0.0101 1156 12518 exclusion phecode
386.1 Meniere's disease Sense Organs 1.17 1.06 – 1.3 0.00209 369 4126 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 1.06 0.93 – 1.2 0.395 250 2655 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.05 0.959 – 1.14 0.3 515 5560 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.03 0.99 – 1.07 0.154 2850 32587 exclusion phecode
388 Other disorders of ear Sense Organs 1.13 0.954 – 1.33 0.16 141 1463 exclusion phecode
389 Hearing loss Sense Organs 1.01 0.97 – 1.05 0.639 2628 29264 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.972 0.861 – 1.1 0.641 296 3179 exclusion phecode
389.2 Conductive hearing loss Sense Organs 0.959 0.85 – 1.08 0.493 296 3354 exclusion phecode
389.4 Tinnitus Sense Organs 0.966 0.863 – 1.08 0.542 336 3644 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.06 1.01 – 1.1 0.00673 2638 32790 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.08 1.03 – 1.14 0.0011 1639 20116 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.03 0.957 – 1.12 0.398 661 8535 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.07 0.98 – 1.16 0.137 555 7030 exclusion phecode
395 Heart valve disorders Circulatory System 1.07 1.03 – 1.12 0.00105 2254 28234 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.09 1.04 – 1.14 0.000852 1586 19409 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.09 0.91 – 1.3 0.353 132 1822 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.03 0.791 – 1.33 0.841 57 709 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.97 0.743 – 1.27 0.824 51 657 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.05 0.976 – 1.13 0.192 743 9813 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.05 0.972 – 1.13 0.217 700 7655 exclusion phecode
401 Hypertension Circulatory System 1.02 1.01 – 1.03 2.59e-05 43185 207901 exclusion phecode
401.1 Essential hypertension Circulatory System 1.02 1.01 – 1.03 2.34e-05 43131 207712 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.08 0.971 – 1.19 0.162 349 13252 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.09 0.939 – 1.27 0.251 157 2564 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.08 0.945 – 1.24 0.25 192 10832 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.13 0.801 – 1.61 0.479 29 1048 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.03 0.965 – 1.11 0.346 908 10889 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.01 0.996 – 1.03 0.133 17437 150784 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.03 0.989 – 1.07 0.168 2818 35061 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.01 0.989 – 1.04 0.286 6320 76419 exclusion phecode
411.3 Angina pectoris Circulatory System 0.997 0.975 – 1.02 0.777 8723 98965 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.01 0.99 – 1.03 0.345 11218 107549 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.991 0.898 – 1.09 0.851 424 4851 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.01 0.989 – 1.03 0.322 7773 89870 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.995 0.922 – 1.07 0.896 695 8291 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 0.996 0.93 – 1.07 0.897 879 12319 exclusion phecode
414.2 ASCVD Circulatory System 1.06 0.776 – 1.45 0.705 38 477 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.04 0.998 – 1.08 0.0602 2401 31183 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.958 0.715 – 1.28 0.772 44 513 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.1 0.975 – 1.24 0.121 266 4029 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.05 0.907 – 1.21 0.534 197 3027 exclusion phecode
416 Cardiomegaly Circulatory System 1.03 0.975 – 1.09 0.297 1300 17990 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.03 1.01 – 1.04 0.000478 18523 198416 exclusion phecode
418.1 Precordial pain Circulatory System 1.04 0.997 – 1.08 0.0709 2284 25880 exclusion phecode
420 Carditis Circulatory System 1.07 1.01 – 1.13 0.0203 1212 14499 exclusion phecode
420.1 Myocarditis Circulatory System 1.07 0.845 – 1.35 0.583 74 906 exclusion phecode
420.2 Pericarditis Circulatory System 1.11 1.03 – 1.19 0.00374 783 9266 exclusion phecode
420.21 Acute pericarditis Circulatory System 0.993 0.844 – 1.17 0.932 152 1553 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.14 0.892 – 1.45 0.299 62 736 exclusion phecode
420.3 Endocarditis Circulatory System 0.993 0.897 – 1.1 0.888 400 4851 exclusion phecode
425 Cardiomyopathy Circulatory System 1.06 0.98 – 1.15 0.14 608 8768 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.05 0.97 – 1.14 0.222 596 8515 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.998 0.783 – 1.27 0.985 68 931 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1 0.808 – 1.24 0.985 89 1171 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.37 0.98 – 1.92 0.0657 28 403 exclusion phecode
426 Cardiac conduction disorders Circulatory System 0.977 0.946 – 1.01 0.171 3814 46144 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 0.957 0.9 – 1.02 0.156 1125 13826 exclusion phecode
426.21 First degree AV block Circulatory System 0.964 0.882 – 1.05 0.423 527 6397 exclusion phecode
426.23 Second degree AV block Circulatory System 0.984 0.868 – 1.12 0.804 268 2957 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 0.952 0.846 – 1.07 0.412 289 3853 exclusion phecode
426.25 Other heart block Circulatory System 1.13 0.899 – 1.42 0.295 75 868 exclusion phecode
426.3 Bundle branch block Circulatory System 1.01 0.963 – 1.06 0.717 1850 22379 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.03 0.957 – 1.1 0.471 840 10047 exclusion phecode
426.32 Left bundle branch block Circulatory System 0.997 0.934 – 1.06 0.926 947 11678 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.916 0.78 – 1.08 0.288 163 1747 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.4 1.02 – 1.94 0.0398 38 404 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.971 0.917 – 1.03 0.305 1258 16287 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.962 0.906 – 1.02 0.2 1155 14951 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1 0.986 – 1.02 0.748 14168 146668 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.01 0.961 – 1.05 0.795 1998 22708 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1 0.95 – 1.05 0.965 1538 16947 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.988 0.903 – 1.08 0.792 501 6314 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.01 0.985 – 1.03 0.508 7861 90141 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.998 0.952 – 1.04 0.917 1921 22082 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.976 0.898 – 1.06 0.56 591 8043 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.937 0.808 – 1.09 0.388 190 2342 exclusion phecode
427.42 Cardiac arrest Circulatory System 0.996 0.909 – 1.09 0.932 476 6663 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.01 0.923 – 1.09 0.906 554 6551 exclusion phecode
427.6 Premature beats Circulatory System 1.06 0.954 – 1.18 0.269 333 3786 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 0.826 0.646 – 1.06 0.126 73 831 exclusion phecode
427.7 Tachycardia NOS Circulatory System 1.01 0.954 – 1.07 0.749 1309 15806 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.09 0.962 – 1.23 0.179 247 2726 exclusion phecode
427.9 Palpitations Circulatory System 0.999 0.959 – 1.04 0.942 2672 28419 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.1 1.06 – 1.15 1.82e-06 2359 36584 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.14 1.06 – 1.23 0.000293 713 13567 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.09 1.04 – 1.14 0.00018 1894 29081 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.04 0.949 – 1.15 0.383 462 5073 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 0.85 0.542 – 1.33 0.479 19 447 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.99 0.884 – 1.11 0.856 336 3689 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.22 1.03 – 1.45 0.0194 126 1424 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.06 1 – 1.13 0.0361 1172 13327 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.11 1.02 – 1.21 0.0193 569 6142 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 1.01 0.916 – 1.11 0.853 439 5232 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.03 0.88 – 1.21 0.689 150 1749 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.01 0.984 – 1.04 0.389 4755 58932 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.01 0.931 – 1.1 0.806 603 7600 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.09 0.907 – 1.3 0.37 123 1453 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 1 0.962 – 1.05 0.849 2213 28187 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.993 0.927 – 1.06 0.85 850 11261 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.03 0.981 – 1.09 0.231 1585 19448 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.03 0.971 – 1.09 0.329 1181 14450 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.03 0.906 – 1.17 0.642 260 2923 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.06 0.982 – 1.15 0.133 632 8793 exclusion phecode
440 Atherosclerosis Circulatory System 0.991 0.913 – 1.08 0.823 602 8853 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.26 0.863 – 1.83 0.235 23 734 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.99 0.893 – 1.1 0.857 365 5154 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 1.01 0.848 – 1.2 0.926 137 1851 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 0.947 0.844 – 1.06 0.351 315 4192 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.899 0.754 – 1.07 0.235 140 1944 exclusion phecode
442 Other aneurysm Circulatory System 1.04 0.974 – 1.11 0.231 871 12071 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.02 0.938 – 1.1 0.692 611 9043 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.03 0.924 – 1.15 0.578 317 5469 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.39 1.02 – 1.91 0.0393 33 605 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.01 0.821 – 1.25 0.916 87 1106 exclusion phecode
442.4 Arterial dissection Circulatory System 1.44 1.08 – 1.92 0.0122 40 411 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.06 0.892 – 1.27 0.498 121 1440 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.02 0.97 – 1.06 0.508 1934 26801 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.06 0.984 – 1.14 0.129 753 8551 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.09 0.91 – 1.31 0.345 111 2583 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.01 0.965 – 1.06 0.647 1857 25181 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.985 0.928 – 1.05 0.614 1122 16871 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 0.994 0.902 – 1.1 0.904 423 6204 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.01 0.886 – 1.14 0.92 236 3651 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.13 1.02 – 1.24 0.0152 395 5738 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 1.18 0.964 – 1.44 0.109 81 1295 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.14 0.999 – 1.31 0.0523 206 2622 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.13 0.938 – 1.37 0.194 106 1715 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 0.955 0.88 – 1.04 0.267 621 8868 exclusion phecode
447.1 Stricture of artery Circulatory System 0.991 0.897 – 1.1 0.857 397 5654 exclusion phecode
448 Disease of capillaries Circulatory System 1.01 0.811 – 1.25 0.955 86 1027 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.06 0.953 – 1.17 0.294 381 5156 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.04 0.995 – 1.08 0.0883 2252 27957 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.05 1 – 1.1 0.0353 2088 25960 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 0.99 0.882 – 1.11 0.87 305 4118 exclusion phecode
454 Varicose veins Circulatory System 1.01 0.983 – 1.03 0.629 8006 83774 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1 0.979 – 1.02 0.897 8287 85950 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.898 0.801 – 1.01 0.064 338 4442 exclusion phecode
455 Hemorrhoids Circulatory System 1.01 0.995 – 1.03 0.192 16487 171594 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.11 0.898 – 1.36 0.342 85 1265 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.05 0.818 – 1.34 0.716 69 663 exclusion phecode
458 Hypotension Circulatory System 1.04 1 – 1.08 0.0383 3122 40224 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.01 0.936 – 1.09 0.782 676 8957 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.1 0.918 – 1.32 0.297 118 1585 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.03 0.987 – 1.08 0.165 1883 24554 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.02 1 – 1.05 0.0281 8927 112673 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 0.978 0.777 – 1.23 0.847 74 993 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.03 1 – 1.05 0.0204 8849 111669 exclusion phecode
464 Acute sinusitis Respiratory 1.1 0.922 – 1.31 0.295 131 1476 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.01 0.956 – 1.06 0.792 1510 16828 exclusion phecode
465.2 Acute pharyngitis Respiratory 1.05 0.959 – 1.14 0.313 553 6196 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 1.02 0.847 – 1.23 0.815 110 1204 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.05 1.01 – 1.09 0.00683 3440 34890 exclusion phecode
471 Nasal polyps Respiratory 1.02 0.982 – 1.07 0.277 2359 23487 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.07 0.992 – 1.16 0.0773 694 7120 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.02 0.97 – 1.07 0.454 1688 18166 exclusion phecode
473.1 Chronic laryngitis Respiratory 0.983 0.763 – 1.27 0.893 64 747 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.06 0.907 – 1.23 0.478 172 1889 exclusion phecode
473.4 Voice disturbance Respiratory 0.995 0.921 – 1.07 0.896 706 7600 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1.02 0.966 – 1.08 0.458 1361 14138 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.09 0.986 – 1.2 0.0955 426 4455 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.98 0.913 – 1.05 0.576 868 8975 exclusion phecode
475 Chronic sinusitis Respiratory 1 0.956 – 1.05 0.891 1842 19122 exclusion phecode
476 Allergic rhinitis Respiratory 0.966 0.897 – 1.04 0.36 804 7930 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.01 0.953 – 1.06 0.851 1468 16711 exclusion phecode
478 Throat pain Respiratory 1.1 0.972 – 1.24 0.132 269 2775 exclusion phecode
479 Other upper respiratory disease Respiratory 1.03 0.993 – 1.07 0.112 2863 29922 exclusion phecode
480 Pneumonia Respiratory 1.03 1.01 – 1.06 0.0177 5640 71497 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.04 1.01 – 1.08 0.00939 3627 46061 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.05 1.01 – 1.08 0.014 3210 40833 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.02 0.77 – 1.36 0.881 46 634 exclusion phecode
480.2 Viral pneumonia Respiratory 0.774 0.547 – 1.1 0.149 39 522 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.2 0.901 – 1.6 0.213 42 678 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.992 0.899 – 1.09 0.87 423 5257 exclusion phecode
481 Influenza Respiratory 1 0.864 – 1.16 0.998 191 2422 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.02 0.844 – 1.24 0.828 116 1405 exclusion phecode
495 Asthma Respiratory 1.02 1.01 – 1.04 0.0049 17338 187928 exclusion phecode
495.2 Asthma with exacerbation Respiratory 0.997 0.851 – 1.17 0.966 164 1912 exclusion phecode
496 Chronic airway obstruction Respiratory 1.04 1.01 – 1.07 0.00752 5308 69214 exclusion phecode
496.1 Emphysema Respiratory 1.06 0.987 – 1.13 0.116 851 11564 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.04 0.985 – 1.1 0.155 1317 19655 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.04 0.983 – 1.1 0.166 1184 17996 exclusion phecode
496.3 Bronchiectasis Respiratory 0.984 0.926 – 1.05 0.607 1112 13006 exclusion phecode
497 Bronchitis Respiratory 1 0.894 – 1.12 0.996 345 4518 exclusion phecode
500 Lung disease due to external agents Respiratory 1.01 0.877 – 1.16 0.895 190 2563 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.09 0.8 – 1.49 0.581 37 557 exclusion phecode
500.2 Pneumoconiosis Respiratory 0.923 0.761 – 1.12 0.421 105 1418 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1 0.893 – 1.12 0.988 319 4401 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.09 0.988 – 1.2 0.0876 411 6032 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 0.93 0.802 – 1.08 0.337 188 3519 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.24 1.05 – 1.46 0.00976 142 2260 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.08 0.767 – 1.51 0.67 34 435 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.07 0.988 – 1.15 0.0953 651 8026 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1.02 0.982 – 1.05 0.365 3569 43880 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1.01 0.947 – 1.07 0.842 1123 13891 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.07 1.01 – 1.13 0.0266 1185 17527 exclusion phecode
509.1 Respiratory failure Respiratory 1.11 1.04 – 1.18 0.00169 923 13859 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.12 1.04 – 1.2 0.00145 807 12198 exclusion phecode
509.5 Respiratory arrest Respiratory 1.06 0.851 – 1.33 0.583 74 1008 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.94 0.809 – 1.09 0.414 184 2579 exclusion phecode
510 Other diseases of lung Respiratory 1.13 1.03 – 1.24 0.0136 432 5174 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.07 1.04 – 1.1 4.83e-06 5300 64335 exclusion phecode
512.1 Wheezing Respiratory 0.975 0.81 – 1.17 0.784 126 1550 exclusion phecode
512.2 Painful respiration Respiratory 1.18 0.997 – 1.4 0.0541 140 1523 exclusion phecode
512.7 Shortness of breath Respiratory 1.06 1.02 – 1.1 0.00131 3323 41531 exclusion phecode
512.8 Cough Respiratory 1.08 1.03 – 1.13 0.00204 1711 20522 exclusion phecode
512.9 Other dyspnea Respiratory 1.09 0.997 – 1.18 0.0588 532 6453 exclusion phecode
513 Respiratory abnormalities Respiratory 1.04 0.933 – 1.16 0.47 344 4276 exclusion phecode
513.3 Hypoventilation Respiratory 1.16 0.806 – 1.66 0.428 31 572 exclusion phecode
513.4 Hyperventilation Respiratory 1.01 0.86 – 1.18 0.944 173 2037 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.13 0.916 – 1.38 0.26 94 1002 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.1 1.04 – 1.16 0.000572 1360 16815 exclusion phecode
516 Abnormal sputum Respiratory 1.04 0.986 – 1.11 0.136 1221 14739 exclusion phecode
516.1 Hemoptysis Respiratory 1.04 0.985 – 1.11 0.144 1196 14347 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.03 1 – 1.06 0.0284 5349 66112 exclusion phecode
519.2 Respiratory complications Respiratory 1.15 0.984 – 1.35 0.0778 149 2197 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.03 0.997 – 1.06 0.0794 5049 62577 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.05 0.911 – 1.2 0.515 216 2189 exclusion phecode
520 Disorders of tooth development Digestive 1.02 0.968 – 1.07 0.473 1587 16220 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.96 0.673 – 1.37 0.823 33 402 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.992 0.946 – 1.04 0.744 1872 18920 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.03 0.981 – 1.08 0.255 1978 22781 exclusion phecode
521.1 Dental caries Digestive 1.03 0.979 – 1.07 0.291 1980 22849 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.03 0.971 – 1.09 0.352 1276 13546 exclusion phecode
522.5 Periapical abscess Digestive 1.05 0.978 – 1.12 0.184 834 8939 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.04 0.98 – 1.1 0.198 1208 12891 exclusion phecode
523.1 Gingivitis Digestive 1.08 0.862 – 1.34 0.521 73 795 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.05 0.981 – 1.13 0.158 859 9141 exclusion phecode
523.31 Acute periodontitis Digestive 1.02 0.928 – 1.12 0.708 499 5333 exclusion phecode
523.32 Chronic periodontitis Digestive 1.08 0.983 – 1.2 0.106 405 4296 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.1 0.972 – 1.25 0.129 250 2629 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.11 0.968 – 1.26 0.139 230 2442 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.977 0.93 – 1.03 0.35 1776 19685 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.28 0.992 – 1.65 0.0578 55 521 exclusion phecode
526 Diseases of the jaws Digestive 1.02 0.944 – 1.11 0.583 657 7001 exclusion phecode
526.1 Cysts of the jaws Digestive 0.94 0.822 – 1.08 0.371 234 2404 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.13 0.868 – 1.48 0.357 49 473 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.11 0.95 – 1.29 0.194 168 1904 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.12 0.96 – 1.31 0.147 164 1846 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 1.03 0.807 – 1.31 0.823 75 816 exclusion phecode
526.9 Jaw disease NOS Digestive 0.98 0.828 – 1.16 0.815 158 1726 exclusion phecode
527 Diseases of the salivary glands Digestive 1.04 0.947 – 1.15 0.394 455 5107 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.2 0.921 – 1.57 0.174 54 601 exclusion phecode
527.2 Sialoadenitis Digestive 1.01 0.885 – 1.15 0.878 240 2739 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 0.935 0.675 – 1.29 0.683 42 460 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 0.948 0.756 – 1.19 0.644 84 875 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.99 0.951 – 1.03 0.632 2634 28527 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.07 0.953 – 1.2 0.248 301 3440 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.05 0.926 – 1.19 0.437 248 2842 exclusion phecode
528.12 Oral aphthae Digestive 1.18 0.9 – 1.54 0.234 56 628 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 0.987 0.815 – 1.2 0.897 114 1341 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.923 0.74 – 1.15 0.475 90 909 exclusion phecode
528.41 Cyst of the salivary gland Digestive 0.9 0.694 – 1.17 0.431 65 703 exclusion phecode
528.5 Diseases of lips Digestive 1 0.914 – 1.1 0.927 474 5001 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 0.837 0.717 – 0.976 0.023 194 2174 exclusion phecode
528.7 Sialolithiasis Digestive 0.935 0.813 – 1.08 0.346 219 2313 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.04 0.973 – 1.12 0.227 829 9018 exclusion phecode
529.1 Glossitis Digestive 1.17 1.01 – 1.35 0.0342 186 2166 exclusion phecode
530 Diseases of esophagus Digestive 1.02 1.01 – 1.04 0.00112 21728 206908 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.03 1.01 – 1.04 0.000233 20403 201209 exclusion phecode
530.11 GERD Digestive 1.03 1.01 – 1.04 0.00193 14956 164974 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.05 1.01 – 1.09 0.0105 3155 35906 exclusion phecode
530.14 Reflux esophagitis Digestive 1.03 1.01 – 1.06 0.0062 6827 75648 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.988 0.925 – 1.06 0.723 943 11936 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 0.997 0.94 – 1.06 0.932 1178 12933 exclusion phecode
530.5 Disorders of esophageal motility Digestive 0.989 0.894 – 1.09 0.836 399 4577 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.03 0.851 – 1.25 0.75 101 1024 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.967 0.839 – 1.11 0.644 215 2522 exclusion phecode
530.9 Heartburn Digestive 0.99 0.938 – 1.04 0.711 1495 15580 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.02 0.984 – 1.05 0.33 4226 49668 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.08 0.974 – 1.2 0.141 352 4319 exclusion phecode
531.2 Gastric ulcer Digestive 0.999 0.958 – 1.04 0.949 2423 28820 exclusion phecode
531.3 Duodenal ulcer Digestive 1.02 0.976 – 1.07 0.328 1799 20881 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 0.973 0.853 – 1.11 0.687 239 2939 exclusion phecode
532 Dysphagia Digestive 1.01 0.981 – 1.04 0.457 4228 46637 exclusion phecode
535 Gastritis and duodenitis Digestive 1.01 0.993 – 1.02 0.27 18173 191285 exclusion phecode
535.1 Acute gastritis Digestive 1.01 0.938 – 1.09 0.78 717 8385 exclusion phecode
535.2 Atrophic gastritis Digestive 1 0.878 – 1.14 0.969 234 2533 exclusion phecode
535.6 Duodenitis Digestive 1.01 0.976 – 1.04 0.725 4682 54128 exclusion phecode
535.8 Other specified gastritis Digestive 1.01 0.982 – 1.04 0.474 5239 57860 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.01 0.809 – 1.27 0.913 83 858 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.06 0.913 – 1.23 0.438 175 1868 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.03 0.989 – 1.08 0.141 2045 24138 exclusion phecode
540 Appendiceal conditions Digestive 0.997 0.955 – 1.04 0.884 2266 23459 exclusion phecode
540.1 Appendicitis Digestive 0.994 0.951 – 1.04 0.781 2134 21972 exclusion phecode
540.11 Acute appendicitis Digestive 0.984 0.94 – 1.03 0.496 1944 19778 exclusion phecode
550 Abdominal hernia Digestive 1.01 1 – 1.02 0.0558 29510 211276 exclusion phecode
550.1 Inguinal hernia Digestive 0.99 0.97 – 1.01 0.324 10584 84628 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.02 1.01 – 1.04 0.00196 16946 174899 exclusion phecode
550.3 Femoral hernia Digestive 0.95 0.866 – 1.04 0.276 492 4835 exclusion phecode
550.4 Umbilical hernia Digestive 1.08 1.04 – 1.13 0.000339 2206 26237 exclusion phecode
550.5 Ventral hernia Digestive 1.01 0.963 – 1.05 0.752 2061 24752 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.02 0.979 – 1.06 0.388 2931 33097 exclusion phecode
555.1 Regional enteritis Digestive 1.01 0.955 – 1.08 0.64 1107 13156 exclusion phecode
555.2 Ulcerative colitis Digestive 1.01 0.965 – 1.05 0.712 2119 23491 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1.02 0.918 – 1.13 0.735 381 4097 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.09 1.01 – 1.18 0.0191 693 7778 exclusion phecode
556.1 Ulceration of intestine Digestive 1.04 0.945 – 1.15 0.413 429 4916 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 1.02 0.879 – 1.18 0.815 198 2289 exclusion phecode
557.1 Celiac disease Digestive 0.969 0.914 – 1.03 0.278 1289 13848 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.03 1.01 – 1.05 0.0049 10139 116051 exclusion phecode
559 Ileostomy status Digestive 0.994 0.932 – 1.06 0.858 998 11716 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.03 0.989 – 1.07 0.153 2534 28294 exclusion phecode
560.1 Paralytic ileus Digestive 1.05 0.941 – 1.18 0.371 318 3637 exclusion phecode
560.2 Impaction of intestine Digestive 1.11 0.952 – 1.29 0.188 165 1951 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.964 0.882 – 1.05 0.414 547 6023 exclusion phecode
560.4 Other intestinal obstruction Digestive 1.01 0.966 – 1.05 0.696 2181 24215 exclusion phecode
561 Symptoms involving digestive system Digestive 1 0.981 – 1.02 0.955 11071 118093 exclusion phecode
561.1 Diarrhea Digestive 0.954 0.848 – 1.07 0.435 307 3348 exclusion phecode
561.2 Flatulence Digestive 1.01 0.952 – 1.07 0.739 1188 12682 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1.01 0.997 – 1.03 0.101 17018 154122 exclusion phecode
562.1 Diverticulosis Digestive 1.01 0.997 – 1.03 0.113 16988 154070 exclusion phecode
563 Constipation Digestive 1.01 0.986 – 1.04 0.379 6720 75745 exclusion phecode
564 Functional digestive disorders Digestive 1.02 0.999 – 1.03 0.0641 14222 154657 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.03 0.998 – 1.06 0.067 4007 42741 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.02 0.962 – 1.09 0.449 1036 11923 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.01 0.989 – 1.03 0.353 9638 108537 exclusion phecode
565 Anal and rectal conditions Digestive 0.994 0.973 – 1.01 0.54 10014 106323 exclusion phecode
565.1 Anal and rectal polyp Digestive 0.993 0.964 – 1.02 0.636 4897 51529 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.05 0.958 – 1.14 0.318 519 6610 exclusion phecode
568 Other disorders of peritoneum Digestive 1.06 1.02 – 1.11 0.00709 2143 24137 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.06 1.02 – 1.11 0.00847 2045 22970 exclusion phecode
569 Other disorders of intestine Digestive 1.03 0.99 – 1.07 0.139 2686 29901 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.991 0.803 – 1.22 0.936 94 1003 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.08 0.961 – 1.2 0.205 318 3425 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.07 1.02 – 1.13 0.00652 1504 21458 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.07 0.999 – 1.14 0.054 944 12403 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.99 0.762 – 1.29 0.94 55 810 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.13 0.935 – 1.36 0.21 105 1910 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.07 0.976 – 1.18 0.143 430 6942 exclusion phecode
571.81 Portal hypertension Digestive 1.14 0.996 – 1.3 0.0566 214 3717 exclusion phecode
572 Ascites (non malignant) Digestive 1.1 1.03 – 1.17 0.0065 870 11009 exclusion phecode
573 Other disorders of liver Digestive 1.08 1.01 – 1.16 0.025 842 10720 exclusion phecode
573.2 Liver replaced by transplant Digestive 0.849 0.51 – 1.41 0.53 15 719 exclusion phecode
573.3 Hepatomegaly Digestive 1.08 0.924 – 1.27 0.322 145 2103 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 0.999 0.913 – 1.09 0.98 498 6264 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.04 0.991 – 1.08 0.116 2045 24822 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.04 0.869 – 1.24 0.676 118 1416 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.02 1 – 1.04 0.0502 9995 116039 exclusion phecode
574.1 Cholelithiasis Digestive 1.01 0.993 – 1.04 0.195 8674 100916 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.975 0.911 – 1.04 0.456 915 10927 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.03 0.997 – 1.07 0.0783 3535 40608 exclusion phecode
574.2 Calculus of bile duct Digestive 1.07 1.02 – 1.13 0.00852 1591 19218 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.03 0.982 – 1.08 0.209 1684 20184 exclusion phecode
575 Other biliary tract disease Digestive 1.04 0.997 – 1.08 0.0664 2417 28197 exclusion phecode
575.1 Cholangitis Digestive 1 0.881 – 1.14 0.972 246 3359 exclusion phecode
575.2 Obstruction of bile duct Digestive 0.991 0.901 – 1.09 0.849 469 5513 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.971 0.867 – 1.09 0.617 329 3555 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.05 0.981 – 1.12 0.165 903 10419 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.07 0.99 – 1.16 0.0875 629 7533 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.11 0.965 – 1.28 0.145 201 2448 exclusion phecode
577 Diseases of pancreas Digestive 1.07 1.02 – 1.13 0.0054 1539 18975 exclusion phecode
577.1 Acute pancreatitis Digestive 1.09 1.03 – 1.16 0.00247 1156 14294 exclusion phecode
577.2 Chronic pancreatitis Digestive 0.974 0.865 – 1.1 0.669 289 3652 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.02 0.89 – 1.17 0.76 214 2618 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.992 – 1.03 0.303 14019 150844 exclusion phecode
578.1 Hematemesis Digestive 0.979 0.921 – 1.04 0.491 1103 13997 exclusion phecode
578.2 Blood in stool Digestive 0.989 0.94 – 1.04 0.682 1574 18437 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.02 0.997 – 1.04 0.0846 9164 96331 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.989 0.955 – 1.02 0.518 3559 38564 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.06 0.99 – 1.13 0.0986 915 11399 exclusion phecode
579.2 Splenomegaly Digestive 1.17 1.01 – 1.36 0.0325 164 2991 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.01 0.945 – 1.07 0.864 1127 11968 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.13 1.01 – 1.25 0.0298 320 10528 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.16 1.01 – 1.33 0.0325 189 7088 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.04 0.682 – 1.59 0.853 18 560 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.978 0.717 – 1.33 0.89 37 957 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.21 1.04 – 1.42 0.0169 140 5813 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.14 0.953 – 1.36 0.154 113 3276 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.982 0.771 – 1.25 0.885 66 1741 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 0.97 0.763 – 1.23 0.8 67 1798 exclusion phecode
585 Renal failure Genitourinary 1.08 1.03 – 1.12 0.000451 2224 47440 exclusion phecode
585.1 Acute renal failure Genitourinary 1.06 1.01 – 1.11 0.0293 1647 30586 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.09 0.99 – 1.2 0.0798 407 10013 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.11 1.01 – 1.22 0.0234 445 17878 exclusion phecode
585.31 Renal dialysis Genitourinary 1.2 0.958 – 1.49 0.114 67 3525 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.04 0.986 – 1.09 0.156 1613 23513 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.05 0.802 – 1.39 0.704 46 1460 exclusion phecode
586.11 Small kidney Genitourinary 1.13 0.837 – 1.52 0.431 38 1242 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.04 0.965 – 1.13 0.287 653 8642 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.08 0.745 – 1.56 0.695 26 569 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.04 0.945 – 1.14 0.452 473 6532 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.24 0.876 – 1.77 0.222 24 2697 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 0.934 0.603 – 1.45 0.759 21 735 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 0.893 0.661 – 1.21 0.465 42 808 exclusion phecode
590 Pyelonephritis Genitourinary 1.03 0.963 – 1.11 0.357 801 10146 exclusion phecode
591 Urinary tract infection Genitourinary 1 0.977 – 1.02 0.967 7516 88690 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.01 0.969 – 1.06 0.537 1928 21171 exclusion phecode
592.1 Cystitis Genitourinary 1.01 0.96 – 1.05 0.791 1886 20769 exclusion phecode
592.11 Acute cystitis Genitourinary 0.96 0.771 – 1.19 0.714 86 944 exclusion phecode
592.12 Chronic cystitis Genitourinary 0.976 0.896 – 1.06 0.58 577 6386 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 1.03 0.886 – 1.21 0.673 173 1820 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.13 0.949 – 1.34 0.171 121 1186 exclusion phecode
593 Hematuria Genitourinary 0.989 0.97 – 1.01 0.299 10355 112993 exclusion phecode
594 Urinary calculus Genitourinary 0.992 0.961 – 1.03 0.646 3976 45158 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.04 0.99 – 1.08 0.131 1936 22297 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 0.922 0.835 – 1.02 0.107 430 5060 exclusion phecode
594.3 Calculus of ureter Genitourinary 1 0.951 – 1.06 0.934 1479 17012 exclusion phecode
594.8 Renal colic Genitourinary 0.976 0.923 – 1.03 0.4 1333 14789 exclusion phecode
595 Hydronephrosis Genitourinary 1 0.943 – 1.07 0.903 1061 13692 exclusion phecode
596 Other disorders of bladder Genitourinary 1.02 0.993 – 1.05 0.165 6147 66514 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 0.976 0.92 – 1.04 0.423 1187 12461 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1 0.942 – 1.07 0.959 1093 12035 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.02 0.977 – 1.06 0.396 2569 27514 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.01 0.971 – 1.06 0.527 2151 23144 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.08 0.794 – 1.47 0.621 38 544 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 0.985 0.944 – 1.03 0.505 2262 24317 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.886 0.752 – 1.04 0.15 158 2095 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.987 – 1.02 0.549 12379 133880 exclusion phecode
599.1 Urinary obstruction Genitourinary 1.06 0.85 – 1.32 0.603 79 1139 exclusion phecode
599.2 Retention of urine Genitourinary 1.04 1 – 1.07 0.0299 3915 44012 exclusion phecode
599.3 Dysuria Genitourinary 1 0.929 – 1.08 0.978 767 8611 exclusion phecode
599.4 Urinary incontinence Genitourinary 1 0.979 – 1.03 0.73 6225 66676 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.02 0.978 – 1.06 0.403 2659 28363 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.09 0.802 – 1.48 0.583 37 695 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 0.934 0.67 – 1.3 0.687 37 432 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1.05 0.992 – 1.11 0.0932 1246 13115 exclusion phecode
600 Hyperplasia of prostate Genitourinary 1.01 0.983 – 1.03 0.525 6386 55946 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 1.03 0.972 – 1.09 0.332 1239 13404 exclusion phecode
601.1 Prostatitis Genitourinary 1.07 1 – 1.14 0.0416 935 9926 exclusion phecode
601.11 Acute prostatitis Genitourinary 1.03 0.867 – 1.21 0.772 135 1527 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1.05 0.965 – 1.14 0.254 548 5689 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 1.09 0.819 – 1.46 0.546 45 421 exclusion phecode
601.4 Balanoposthitis Genitourinary 1.01 0.867 – 1.17 0.928 179 1907 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.951 0.81 – 1.12 0.537 168 2013 exclusion phecode
602 Other disorders of prostate Genitourinary 1.03 0.961 – 1.11 0.392 787 8223 exclusion phecode
603 Other disorders of testis Genitourinary 0.98 0.927 – 1.04 0.487 1349 14624 exclusion phecode
603.1 Hydrocele Genitourinary 0.963 0.897 – 1.03 0.296 832 8911 exclusion phecode
604 Disorders of penis Genitourinary 1.02 0.979 – 1.07 0.312 2065 22593 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.999 0.951 – 1.05 0.972 1692 18724 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 1.04 0.895 – 1.21 0.598 168 1816 exclusion phecode
608 Other disorders of male genital organs Genitourinary 1.03 0.985 – 1.08 0.179 1823 19075 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.919 0.772 – 1.09 0.337 135 1361 exclusion phecode
609.1 Infertility, male Genitourinary 1.01 0.762 – 1.34 0.941 49 503 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.896 0.732 – 1.1 0.292 99 1002 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.993 0.948 – 1.04 0.759 1972 19921 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.998 0.924 – 1.08 0.955 722 7285 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1.03 0.904 – 1.18 0.644 238 2420 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 0.971 0.847 – 1.11 0.678 235 2364 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.981 0.922 – 1.04 0.542 1121 11242 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1.02 0.928 – 1.11 0.722 522 5394 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.03 0.974 – 1.09 0.276 1239 12358 exclusion phecode
611.1 Abnormal mammogram Genitourinary 1.11 0.822 – 1.51 0.485 48 428 exclusion phecode
611.3 Lump or mass in breast Genitourinary 1.04 0.978 – 1.1 0.224 1195 11952 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.01 0.929 – 1.09 0.889 675 7059 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 0.992 0.914 – 1.08 0.845 644 6692 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 1.17 0.906 – 1.51 0.228 62 597 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.973 0.916 – 1.03 0.365 1213 13058 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 0.954 0.87 – 1.05 0.315 519 5681 exclusion phecode
613.5 Mastodynia Genitourinary 0.776 0.571 – 1.05 0.103 52 617 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 1.03 0.941 – 1.12 0.545 543 5480 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1 0.879 – 1.14 0.991 252 2598 exclusion phecode
613.9 Breast disorder NOS Genitourinary – 154 1613 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.98 0.95 – 1.01 0.209 4555 46930 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.968 0.924 – 1.01 0.176 2029 21054 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 1 0.926 – 1.09 0.954 674 6917 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.01 0.747 – 1.36 0.952 50 511 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.998 0.892 – 1.12 0.965 335 3472 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 1.01 0.894 – 1.15 0.837 284 2951 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.981 0.853 – 1.13 0.793 219 2266 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.987 0.942 – 1.03 0.562 2070 21159 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.999 0.938 – 1.07 0.986 1039 10678 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.02 0.914 – 1.14 0.697 334 3428 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.959 0.882 – 1.04 0.322 632 6251 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 1 0.869 – 1.15 0.998 205 2238 exclusion phecode
615 Endometriosis Genitourinary 0.983 0.948 – 1.02 0.368 3310 33907 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.11 0.972 – 1.26 0.125 222 2413 exclusion phecode
618 Genital prolapse Genitourinary 1.01 0.991 – 1.04 0.233 8798 89103 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 1.02 0.992 – 1.05 0.158 5502 56218 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.01 0.976 – 1.04 0.657 4144 40977 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.02 0.915 – 1.13 0.742 373 3802 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.02 0.928 – 1.12 0.676 475 5087 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1.01 0.984 – 1.03 0.51 6911 70025 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1 0.921 – 1.09 0.942 582 5971 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 0.987 0.947 – 1.03 0.536 2576 26151 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.03 0.99 – 1.08 0.138 2316 23245 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.06 1 – 1.12 0.0498 1403 14196 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.98 0.919 – 1.04 0.527 1065 10872 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1.12 0.854 – 1.48 0.404 51 574 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.956 0.889 – 1.03 0.23 819 8975 exclusion phecode
622 Polyp of female genital organs Genitourinary 1.01 0.983 – 1.03 0.649 8117 82727 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 1 0.977 – 1.03 0.81 5988 62113 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 1 0.962 – 1.04 0.965 2767 26862 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.02 0.953 – 1.08 0.623 1009 10437 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.955 0.876 – 1.04 0.293 582 6032 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.986 0.844 – 1.15 0.862 171 1815 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 0.953 0.847 – 1.07 0.423 320 3333 exclusion phecode
624.9 stress incontinence, female Genitourinary 1 0.974 – 1.04 0.765 4407 45979 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1.02 0.973 – 1.06 0.482 2427 24139 exclusion phecode
625.1 Dyspareunia Genitourinary 1.03 0.967 – 1.1 0.333 990 9975 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.01 0.99 – 1.03 0.377 13511 95319 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.01 0.993 – 1.03 0.229 11804 91590 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.914 0.725 – 1.15 0.443 86 937 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1.02 0.997 – 1.04 0.0847 8024 77074 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.999 0.948 – 1.05 0.961 1612 16218 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 1.01 0.973 – 1.05 0.62 3186 32196 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.974 0.922 – 1.03 0.35 1464 15245 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 1.21 1.02 – 1.45 0.0301 119 1378 exclusion phecode
626.8 Infertility, female Genitourinary 0.987 0.929 – 1.05 0.672 1228 12044 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.02 0.992 – 1.04 0.211 7565 79145 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 1.01 0.984 – 1.03 0.496 6532 68560 exclusion phecode
627.2 Symptomatic menopause Genitourinary 1.16 0.981 – 1.37 0.0824 136 1443 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.01 0.939 – 1.09 0.783 797 8226 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1.12 0.98 – 1.27 0.0964 241 2526 exclusion phecode
628 Ovarian cyst Genitourinary 0.994 0.961 – 1.03 0.729 3823 39143 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.987 0.957 – 1.02 0.428 4734 32491 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.03 0.965 – 1.1 0.381 1022 10166 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.01 0.895 – 1.14 0.889 301 2930 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.998 0.949 – 1.05 0.947 1817 15648 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.996 0.923 – 1.07 0.908 798 7773 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.995 0.935 – 1.06 0.881 1167 11078 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.02 0.971 – 1.06 0.49 2145 17938 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 1 0.919 – 1.1 0.92 563 5515 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.02 0.952 – 1.09 0.612 985 9563 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 0.959 0.717 – 1.28 0.778 61 625 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.976 0.912 – 1.04 0.487 981 10029 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.09 0.963 – 1.24 0.17 271 2751 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.817 0.694 – 0.962 0.0151 185 1948 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.878 0.727 – 1.06 0.18 131 1363 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.997 0.937 – 1.06 0.914 1147 11281 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.999 0.953 – 1.05 0.963 2016 18854 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.03 0.799 – 1.33 0.815 59 600 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.11 0.978 – 1.26 0.107 258 2476 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.937 0.763 – 1.15 0.539 103 1010 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.987 0.84 – 1.16 0.876 176 1744 exclusion phecode
650 Normal delivery Pregnancy Complications 1.02 0.97 – 1.07 0.433 1772 17119 exclusion phecode
651 Multiple gestation Pregnancy Complications 0.963 0.853 – 1.09 0.543 310 3126 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.975 0.924 – 1.03 0.353 1590 14954 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1.01 0.95 – 1.07 0.785 1281 12312 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.42 1.1 – 1.82 0.00617 66 656 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.972 0.939 – 1.01 0.113 3940 26537 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.07 0.875 – 1.32 0.498 95 977 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.945 0.9 – 0.991 0.0198 2086 16594 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.954 0.866 – 1.05 0.341 492 4803 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.977 0.946 – 1.01 0.157 4864 26481 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.997 0.954 – 1.04 0.892 2333 19087 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.833 0.688 – 1.01 0.0603 146 1472 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.979 0.857 – 1.12 0.761 241 2368 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.987 0.745 – 1.31 0.929 58 565 exclusion phecode
679 Complications of in utero procedures Dermatologic 1.16 0.865 – 1.56 0.318 48 490 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.04 1.01 – 1.07 0.0122 4027 51507 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.92 0.824 – 1.03 0.141 353 4109 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.02 0.911 – 1.13 0.768 346 3838 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.04 1 – 1.08 0.0309 2928 38974 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.04 1.01 – 1.08 0.0224 2932 39017 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.04 1 – 1.08 0.0284 2904 38675 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.19 1.07 – 1.31 0.00109 358 4375 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.14 1.06 – 1.22 0.000225 807 9636 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.05 0.998 – 1.11 0.061 1475 17138 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.02 0.924 – 1.13 0.68 404 4550 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 0.872 0.764 – 0.995 0.0421 255 2627 exclusion phecode
687 Symptoms affecting skin Dermatologic 1.17 1.06 – 1.3 0.003 351 3979 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.02 0.968 – 1.08 0.414 1288 15623 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.19 1.03 – 1.37 0.0171 195 2039 exclusion phecode
687.3 Changes in skin texture Dermatologic 1.15 0.906 – 1.46 0.249 71 794 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.03 0.981 – 1.08 0.26 1962 21730 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.977 0.945 – 1.01 0.162 3950 41432 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.909 0.678 – 1.22 0.526 46 529 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.787 0.55 – 1.13 0.19 36 386 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.753 0.588 – 0.965 0.0248 80 876 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.94 0.869 – 1.02 0.121 723 7202 exclusion phecode
694.1 Vitiligo Dermatologic 0.925 0.651 – 1.31 0.663 39 445 exclusion phecode
694.2 Other dyschromia Dermatologic 0.926 0.849 – 1.01 0.0801 597 5704 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.13 0.893 – 1.44 0.302 68 847 exclusion phecode
695 Erythematous conditions Dermatologic 0.994 0.942 – 1.05 0.812 1513 17392 exclusion phecode
695.1 Toxic erythema Dermatologic 1.23 0.975 – 1.55 0.0802 66 829 exclusion phecode
695.2 Bullous dermatoses Dermatologic 1.02 0.823 – 1.26 0.856 87 966 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 0.947 0.687 – 1.31 0.741 36 395 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 1.16 0.877 – 1.53 0.302 48 516 exclusion phecode
695.3 Rosacea Dermatologic 1.06 0.926 – 1.21 0.4 224 2212 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 0.992 0.862 – 1.14 0.907 219 3148 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.837 0.652 – 1.07 0.162 71 955 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1 0.862 – 1.17 0.952 179 2643 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 0.972 0.888 – 1.06 0.541 527 5652 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 1 0.852 – 1.18 0.964 146 1752 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.778 0.582 – 1.04 0.0915 55 604 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 0.957 0.844 – 1.08 0.493 280 3288 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.972 0.918 – 1.03 0.321 1320 16391 exclusion phecode
696.4 Psoriasis Dermatologic 0.978 0.923 – 1.04 0.442 1285 16044 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.978 0.915 – 1.05 0.513 954 12132 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 1.02 0.924 – 1.12 0.732 450 5291 exclusion phecode
697 Sarcoidosis Dermatologic 1.14 1.01 – 1.28 0.0355 268 4024 exclusion phecode
698 Pruritus and related conditions Dermatologic 0.988 0.906 – 1.08 0.788 550 5719 exclusion phecode
700 Corns and callosities Dermatologic 0.975 0.838 – 1.13 0.744 185 2154 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.02 0.981 – 1.05 0.374 3312 34327 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.814 0.609 – 1.09 0.165 54 590 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.02 0.97 – 1.07 0.456 1716 17453 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 1.28 0.941 – 1.74 0.116 38 428 exclusion phecode
701.4 Keloid scar Dermatologic 0.982 0.838 – 1.15 0.822 162 1675 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1.07 0.954 – 1.19 0.263 338 3396 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 0.913 0.706 – 1.18 0.489 64 767 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.996 0.963 – 1.03 0.809 3821 38063 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.994 0.947 – 1.04 0.818 1753 17669 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 0.995 0.952 – 1.04 0.826 2208 21594 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1 0.877 – 1.15 0.946 230 2525 exclusion phecode
703.1 Ingrowing nail Dermatologic 1.11 1.02 – 1.2 0.0112 620 7152 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 1.05 1.01 – 1.08 0.00631 3837 39206 exclusion phecode
704.1 Alopecia Dermatologic 0.971 0.776 – 1.22 0.798 83 992 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.06 0.821 – 1.36 0.672 58 561 exclusion phecode
705 Disorders of sweat glands Dermatologic 1.08 0.913 – 1.28 0.363 139 1822 exclusion phecode
705.3 Hidradenitis Dermatologic 1.02 0.846 – 1.23 0.835 114 1494 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.13 1.02 – 1.25 0.0208 361 4228 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1.04 1.02 – 1.07 0.00187 6063 61421 exclusion phecode
706.1 Acne Dermatologic 1.35 1.05 – 1.73 0.0179 57 622 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1.03 1.01 – 1.06 0.018 6421 64821 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.07 1 – 1.15 0.0466 823 13259 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.03 0.935 – 1.13 0.555 426 6025 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 1.01 0.97 – 1.06 0.572 2182 24985 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.11 0.982 – 1.25 0.0972 260 3817 exclusion phecode
709.3 Systemic sclerosis Dermatologic 1.1 0.894 – 1.35 0.37 90 1293 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.39 1.02 – 1.89 0.0351 32 505 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.987 0.941 – 1.04 0.604 1812 19648 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.11 0.985 – 1.24 0.0888 290 4237 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.08 0.958 – 1.22 0.2 266 3944 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.12 0.917 – 1.37 0.268 99 1413 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.07 0.92 – 1.24 0.385 176 2796 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 1.15 1.01 – 1.3 0.0311 246 3048 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.18 1.02 – 1.36 0.0224 183 2351 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.34 1.02 – 1.76 0.0384 46 569 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.16 0.911 – 1.46 0.233 65 1078 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.27 0.814 – 1.98 0.293 15 445 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.03 0.992 – 1.07 0.123 2698 35492 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.02 0.983 – 1.07 0.248 2421 32196 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.987 0.926 – 1.05 0.692 1023 12060 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.97 0.763 – 1.23 0.802 72 897 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.05 0.95 – 1.16 0.335 379 4404 exclusion phecode
716 Other arthropathies Musculoskeletal 1.04 1.02 – 1.05 2.04e-07 23477 196989 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.06 1.01 – 1.11 0.0126 2074 25167 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.03 1.01 – 1.05 0.00196 9596 111168 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.03 1.02 – 1.05 1.03e-06 22494 194363 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.04 0.959 – 1.13 0.344 598 7700 exclusion phecode
720 Spinal stenosis Musculoskeletal 1.04 1 – 1.09 0.0509 2203 25800 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1.01 0.985 – 1.04 0.36 4838 55921 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.02 0.979 – 1.05 0.407 3110 35929 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.904 0.74 – 1.1 0.324 109 1333 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 1.04 0.902 – 1.19 0.619 211 2495 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.04 1.01 – 1.06 0.00902 6074 66959 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.996 0.895 – 1.11 0.947 377 3878 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.06 1.01 – 1.11 0.0207 1811 21082 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 0.966 0.718 – 1.3 0.819 47 524 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.05 1.01 – 1.09 0.0145 2998 32921 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.1 0.983 – 1.22 0.0992 335 3762 exclusion phecode
723.1 Torticollis Musculoskeletal 1.15 0.93 – 1.43 0.194 79 818 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.05 0.99 – 1.1 0.107 1386 15228 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 0.975 0.867 – 1.1 0.672 307 3198 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 0.969 0.863 – 1.09 0.602 311 3212 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.19 0.876 – 1.62 0.266 39 439 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.06 0.998 – 1.13 0.0598 1061 11786 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.01 0.989 – 1.03 0.367 10176 107805 exclusion phecode
726.1 Enthesopathy Musculoskeletal 1.01 0.989 – 1.04 0.283 6550 69785 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.905 0.795 – 1.03 0.129 266 2591 exclusion phecode
726.3 Bursitis Musculoskeletal 1 0.92 – 1.09 0.989 564 6223 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.01 0.98 – 1.04 0.558 5229 54739 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.988 0.942 – 1.04 0.611 1873 20440 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 1.08 0.861 – 1.35 0.51 77 733 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 0.999 0.957 – 1.04 0.946 2325 23560 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 1.12 1.01 – 1.24 0.0314 375 4137 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.993 0.871 – 1.13 0.922 242 2529 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.996 0.808 – 1.23 0.969 99 1022 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1 0.964 – 1.05 0.838 2465 24188 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.1 0.984 – 1.23 0.0943 308 3266 exclusion phecode
728.7 Fasciitis Musculoskeletal 1.01 0.969 – 1.05 0.689 2559 25266 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.999 0.958 – 1.04 0.973 2348 22728 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.04 1 – 1.07 0.0247 3620 44027 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.02 0.943 – 1.11 0.589 655 7817 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.998 0.79 – 1.26 0.984 77 746 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.995 0.858 – 1.15 0.948 196 2119 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.993 0.853 – 1.16 0.929 186 2012 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.979 0.875 – 1.09 0.708 344 3573 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.864 0.725 – 1.03 0.101 145 1541 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.09 0.808 – 1.46 0.586 43 451 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.999 0.941 – 1.06 0.981 1196 13157 exclusion phecode
733.2 Cyst of bone Musculoskeletal 0.987 0.859 – 1.13 0.853 225 2302 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.06 0.95 – 1.19 0.279 316 3935 exclusion phecode
733.6 Costochondritis Musculoskeletal 1.06 0.865 – 1.3 0.565 85 939 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.991 0.921 – 1.07 0.797 820 9217 exclusion phecode
733.9 Chondromalacia Musculoskeletal 0.816 0.654 – 1.02 0.0738 93 930 exclusion phecode
735 Acquired foot deformities Musculoskeletal 1.01 0.981 – 1.03 0.681 6982 71984 exclusion phecode
735.1 Flat foot Musculoskeletal 1.07 0.892 – 1.27 0.486 122 1423 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 1.01 0.979 – 1.05 0.444 3551 37254 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.04 0.986 – 1.1 0.142 1329 14089 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.995 0.936 – 1.06 0.873 1142 11378 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.01 0.977 – 1.04 0.674 4947 50311 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1.02 0.956 – 1.09 0.556 1006 11671 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.01 0.866 – 1.19 0.855 171 1820 exclusion phecode
737 Curvature of spine Musculoskeletal 0.986 0.912 – 1.07 0.73 691 8211 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.989 0.912 – 1.07 0.787 649 7702 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1 0.945 – 1.06 0.949 1249 13821 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.954 0.892 – 1.02 0.168 955 10770 exclusion phecode
739 Contracture of joint Musculoskeletal 1.01 0.899 – 1.13 0.889 306 3667 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.04 1.02 – 1.05 6.93e-06 17376 166682 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.03 1.01 – 1.05 0.00108 11040 119049 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.03 1 – 1.06 0.0228 5522 62406 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.01 0.882 – 1.15 0.919 227 2490 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.02 0.914 – 1.14 0.73 343 4215 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.05 1.02 – 1.07 0.000163 7456 87250 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.06 1.02 – 1.11 0.00641 2324 25926 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 1.23 0.963 – 1.57 0.0969 68 725 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.09 0.991 – 1.2 0.0771 450 4582 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 1.09 0.882 – 1.36 0.411 79 1092 exclusion phecode
741.4 Joint effusions Musculoskeletal 1.06 0.989 – 1.14 0.0984 843 10050 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.3 1.02 – 1.65 0.0329 68 795 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.881 0.634 – 1.22 0.451 37 413 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.05 0.999 – 1.09 0.0534 2079 21769 exclusion phecode
742.1 Loose body in joint Musculoskeletal 1.15 1.01 – 1.31 0.0345 236 2417 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.99 0.783 – 1.25 0.933 75 790 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.14 1.02 – 1.27 0.0179 350 3839 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 1.02 0.965 – 1.07 0.514 1489 15364 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.02 0.991 – 1.05 0.179 4923 54050 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.01 0.98 – 1.04 0.474 4147 45488 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.01 0.977 – 1.05 0.557 3611 39824 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1.02 0.917 – 1.15 0.665 319 3471 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1 0.885 – 1.13 0.993 281 3692 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.09 1 – 1.19 0.0381 583 6068 exclusion phecode
745 Pain in joint Musculoskeletal 1.01 0.982 – 1.04 0.493 5204 58798 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.984 0.935 – 1.03 0.522 1632 19231 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.979 0.929 – 1.03 0.441 1509 17983 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.949 0.855 – 1.05 0.321 413 4430 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.893 0.753 – 1.06 0.193 152 1731 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.992 0.929 – 1.06 0.814 929 11802 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1.04 0.869 – 1.24 0.672 116 1230 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.33 0.961 – 1.84 0.0859 35 360 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.17 1.03 – 1.34 0.0187 226 2300 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.997 0.903 – 1.1 0.945 420 4857 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.02 0.886 – 1.17 0.811 206 2222 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.917 0.761 – 1.1 0.363 122 1296 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.01 0.877 – 1.16 0.912 210 2597 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.976 0.831 – 1.15 0.769 158 1622 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.93 0.694 – 1.24 0.624 46 877 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.972 0.907 – 1.04 0.427 905 11418 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.93 0.849 – 1.02 0.125 537 5406 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.985 0.883 – 1.1 0.789 372 3782 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.854 0.722 – 1.01 0.0661 155 1519 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.04 0.937 – 1.15 0.461 370 6043 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 1.22 1.03 – 1.44 0.0185 133 3003 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.979 0.845 – 1.13 0.78 186 2457 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.951 0.829 – 1.09 0.475 231 2580 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.07 0.919 – 1.25 0.382 180 2025 exclusion phecode
752.11 Spina bifida Congenital Anomalies 1.02 0.855 – 1.21 0.857 145 1665 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.735 0.538 – 1 0.0532 54 593 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.13 0.905 – 1.41 0.283 81 953 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.06 0.797 – 1.41 0.687 47 581 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.924 0.727 – 1.17 0.517 72 859 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.05 0.932 – 1.18 0.436 306 3285 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.1 0.935 – 1.3 0.245 153 1554 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.896 0.731 – 1.1 0.288 114 1299 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.818 0.633 – 1.06 0.126 76 870 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.977 0.885 – 1.08 0.65 414 4400 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.997 0.761 – 1.3 0.98 60 635 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.01 0.899 – 1.14 0.856 297 3254 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.21 0.985 – 1.48 0.0701 88 1308 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.13 0.826 – 1.54 0.452 36 648 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.998 0.841 – 1.18 0.983 133 1586 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.05 0.825 – 1.32 0.714 64 704 exclusion phecode
760 Back pain Symptoms 1.02 1 – 1.05 0.043 7241 82599 exclusion phecode
761 Cervicalgia Symptoms 0.984 0.927 – 1.04 0.586 1226 13386 exclusion phecode
764 Sciatica Symptoms 1.04 0.987 – 1.09 0.145 1561 17542 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.07 0.994 – 1.15 0.0722 749 8615 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.12 1.02 – 1.24 0.0169 414 4712 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.981 0.9 – 1.07 0.659 563 6326 exclusion phecode
771.1 Swelling of limb Symptoms 1.04 1 – 1.08 0.0501 2688 33176 exclusion phecode
772 Symptoms of the muscles Symptoms 1.04 0.94 – 1.14 0.471 423 4807 exclusion phecode
773 Pain in limb Symptoms 1.01 0.973 – 1.04 0.74 3953 45671 exclusion phecode
780 Hypothermia/Chills Symptoms 0.998 0.813 – 1.22 0.983 97 1231 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.07 1.01 – 1.13 0.0239 1200 13658 exclusion phecode
782.3 Edema Symptoms 1.04 0.966 – 1.12 0.296 745 11377 exclusion phecode
782.6 Pallor and flushing Symptoms 1.1 0.917 – 1.32 0.299 119 1247 exclusion phecode
783 Fever of unknown origin Symptoms 1.04 0.999 – 1.08 0.0558 2439 28217 exclusion phecode
785 Abdominal pain Symptoms 1.01 1 – 1.03 0.0359 28423 225671 exclusion phecode
788 Syncope and collapse Symptoms 0.997 0.97 – 1.02 0.837 5658 63507 exclusion phecode
789 Nausea and vomiting Symptoms 1.02 0.999 – 1.05 0.0572 7405 85578 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.05 0.852 – 1.29 0.653 87 1038 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 0.874 0.621 – 1.23 0.438 38 573 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.03 0.992 – 1.06 0.142 3644 41750 exclusion phecode
791 Gangrene Symptoms 1.1 0.968 – 1.24 0.151 244 3880 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 1 0.788 – 1.28 0.978 76 727 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 0.96 0.771 – 1.19 0.714 85 945 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 0.96 0.859 – 1.07 0.471 349 3993 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.904 0.727 – 1.12 0.365 96 1018 exclusion phecode
797 Shock Symptoms 1.14 0.921 – 1.41 0.229 77 1011 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.07 0.809 – 1.4 0.652 46 639 exclusion phecode
798 Malaise and fatigue Symptoms 1.01 0.965 – 1.05 0.7 2176 24992 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1.01 0.919 – 1.12 0.793 447 4590 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.02 0.989 – 1.05 0.218 4863 50960 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1 0.944 – 1.06 0.953 1178 12464 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.16 0.958 – 1.4 0.131 105 1222 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.07 1.02 – 1.13 0.00967 1569 16175 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 1.07 0.979 – 1.17 0.139 532 5519 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.02 0.973 – 1.08 0.359 1561 16475 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.04 0.988 – 1.11 0.128 1313 13664 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.02 0.932 – 1.12 0.641 488 5176 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 1.02 0.989 – 1.04 0.252 6088 61074 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1.02 0.965 – 1.09 0.424 1139 12241 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.02 0.991 – 1.06 0.157 3930 38861 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1 0.944 – 1.07 0.911 1111 10928 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 1 0.959 – 1.04 0.998 2464 24889 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.01 0.942 – 1.08 0.82 927 9901 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 0.97 0.888 – 1.06 0.51 526 5437 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.02 0.954 – 1.09 0.538 887 9451 exclusion phecode
817 Concussion Injuries & Poisonings 1.05 0.903 – 1.22 0.531 180 1822 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.08 0.971 – 1.21 0.155 333 3559 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.03 0.988 – 1.08 0.154 2173 22133 exclusion phecode
823 Torus fracture Injuries & Poisonings 1.07 1.01 – 1.14 0.0144 1226 12588 exclusion phecode
830 Dislocation Injuries & Poisonings 0.972 0.922 – 1.02 0.289 1519 15494 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 1.02 1 – 1.04 0.0491 10995 112652 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 1.02 0.914 – 1.13 0.746 366 3840 exclusion phecode
840 Sprains and strains Injuries & Poisonings 1.01 0.911 – 1.13 0.815 358 3560 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.02 0.984 – 1.06 0.288 3428 38344 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.927 0.746 – 1.15 0.493 94 1115 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 0.988 0.874 – 1.12 0.849 276 3525 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.999 0.933 – 1.07 0.978 866 12213 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.975 0.904 – 1.05 0.52 734 8833 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.974 0.93 – 1.02 0.271 1936 22544 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.02 0.974 – 1.07 0.407 2013 23394 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.4 1.04 – 1.9 0.0288 40 530 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.01 0.97 – 1.06 0.592 2338 25149 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.974 0.836 – 1.13 0.735 183 1967 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1.06 0.882 – 1.26 0.556 125 1439 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.03 0.981 – 1.08 0.247 1943 20767 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1 0.85 – 1.18 0.969 148 1535 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.776 0.573 – 1.05 0.1 48 511 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.02 0.978 – 1.05 0.427 2888 29962 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.11 0.817 – 1.5 0.511 41 369 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.13 0.868 – 1.48 0.361 62 656 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.09 0.909 – 1.31 0.349 118 1315 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.02 0.913 – 1.14 0.749 349 3368 exclusion phecode
873 Broken tooth Injuries & Poisonings 1.11 0.948 – 1.31 0.192 158 1673 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.12 0.913 – 1.37 0.281 87 1237 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.09 0.897 – 1.31 0.397 113 1185 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.03 0.962 – 1.1 0.413 910 9756 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.03 0.989 – 1.07 0.156 2732 30875 exclusion phecode
916 Contusion Injuries & Poisonings 1.04 0.971 – 1.11 0.281 958 10427 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.92 0.767 – 1.1 0.369 134 1399 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.03 0.908 – 1.17 0.65 250 2641 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.948 0.81 – 1.11 0.506 168 1712 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.05 0.999 – 1.11 0.0556 1350 15276 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.11 0.948 – 1.31 0.189 152 1568 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.11 0.869 – 1.42 0.401 62 732 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.01 0.902 – 1.13 0.876 333 4070 exclusion phecode
947 Urticaria Injuries & Poisonings 1.04 0.919 – 1.19 0.505 249 2770 exclusion phecode
949 Allergies, other Injuries & Poisonings 0.971 0.858 – 1.1 0.645 280 3065 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.971 0.862 – 1.09 0.626 296 3088 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.02 0.87 – 1.2 0.795 158 1935 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.981 0.873 – 1.1 0.742 310 3587 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.11 0.79 – 1.55 0.559 30 385 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.68 0.493 – 0.938 0.0187 51 506 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.02 1.01 – 1.04 0.00851 12268 135935 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.03 1.01 – 1.05 0.00338 10735 118729 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.02 0.893 – 1.16 0.807 253 3125 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.944 0.865 – 1.03 0.191 575 6701 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.1 0.959 – 1.27 0.17 192 2752 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.12 0.975 – 1.3 0.109 188 2693 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.94 0.792 – 1.11 0.476 148 1787 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.16 0.982 – 1.38 0.0792 121 1978 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.21 1.02 – 1.44 0.0284 116 1929 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.996 0.964 – 1.03 0.798 3968 45867 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.03 0.961 – 1.11 0.367 758 8661 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.09 0.98 – 1.22 0.108 334 3867 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.891 0.78 – 1.02 0.0862 253 2948 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.06 0.947 – 1.18 0.332 347 4037 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.06 0.959 – 1.18 0.248 404 4411 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.02 0.965 – 1.08 0.471 1325 15609 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.933 0.77 – 1.13 0.477 121 1510 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.04 0.882 – 1.22 0.668 157 2049 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 1.02 0.769 – 1.35 0.905 51 670 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.39 1.11 – 1.76 0.00499 66 835 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.19 0.874 – 1.62 0.268 35 711 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.801 0.577 – 1.11 0.185 41 509 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.06 0.755 – 1.48 0.743 39 449 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.961 0.809 – 1.14 0.651 143 1740 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 0.991 0.9 – 1.09 0.858 458 5403 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.964 0.808 – 1.15 0.681 136 1611 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 1.11 0.827 – 1.49 0.486 45 460 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.04 0.805 – 1.34 0.766 61 764 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.897 0.714 – 1.13 0.35 86 877 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.916 0.693 – 1.21 0.541 53 617 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1 0.957 – 1.05 0.931 2013 21824 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1.02 0.974 – 1.08 0.342 1560 21063 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1.02 0.974 – 1.08 0.342 1560 21063 exclusion phecode
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