Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Estimated glomerular filtration rate based on cystatin C UK Biobank (UKB) PheWAS analysis

Estimated glomerular filtration rate based on cystatin C — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID exprsweb-egfr-cystatinc-egfrcys-overall-iv-2gc-dbslmm-ukb-20211120Legacy DBSLMMDBSLMMLarge GWAS

Evaluation cohort: UK Biobank (UKB).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: study-defined normal-range subset.

For this ExPRS, the exclusion sensitivity scan keeps only the study-defined normal-range subset for Estimated glomerular filtration rate based on cystatin C before rerunning the PheWAS. The preserved release does not include numeric bounds for this trait. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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Signal overview

The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.

87 rows visible 14 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 0.994 0.973 – 1.02 0.594 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 0.991 0.953 – 1.03 0.64 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 0.998 0.922 – 1.08 0.969 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 1.01 0.938 – 1.08 0.877 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 1 0.767 – 1.31 0.984 55 550 all phecode
010 Tuberculosis Infectious Diseases 0.925 0.789 – 1.08 0.335 166 1659 all phecode
038 Septicemia Infectious Diseases 0.996 0.965 – 1.03 0.807 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 0.997 0.93 – 1.07 0.935 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 0.999 0.912 – 1.09 0.985 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 1.02 1 – 1.04 0.0305 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.06 1.02 – 1.1 0.00252 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 1.02 0.971 – 1.07 0.418 1641 16433 all phecode
041.4 E. coli Infectious Diseases 1.04 1 – 1.08 0.0496 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 1.06 0.957 – 1.18 0.259 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.1 0.893 – 1.36 0.364 95 949 all phecode
054 Herpes simplex Infectious Diseases 0.904 0.788 – 1.04 0.148 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 0.983 0.903 – 1.07 0.691 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 0.866 0.678 – 1.11 0.251 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 0.93 0.781 – 1.11 0.417 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.04 0.914 – 1.19 0.544 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 0.943 0.835 – 1.06 0.336 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 0.981 0.889 – 1.08 0.697 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.963 0.814 – 1.14 0.661 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.881 0.73 – 1.06 0.188 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 1 0.94 – 1.07 0.924 1004 10036 all phecode
079 Viral infection Infectious Diseases 0.972 0.935 – 1.01 0.16 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 0.831 0.639 – 1.08 0.169 64 640 all phecode
080 Postoperative infection Infectious Diseases 1.01 0.979 – 1.04 0.554 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.02 0.982 – 1.07 0.262 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.873 0.691 – 1.1 0.253 71 709 all phecode
1000 Burns Injuries & Poisonings 1.06 0.975 – 1.16 0.169 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 1.02 0.964 – 1.09 0.443 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1 0.975 – 1.03 0.89 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.04 0.925 – 1.17 0.502 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 0.97 0.919 – 1.02 0.262 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 0.957 0.843 – 1.09 0.493 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 1.07 0.942 – 1.22 0.286 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.02 0.954 – 1.09 0.602 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 1.01 0.985 – 1.03 0.536 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 0.998 0.972 – 1.02 0.882 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.988 0.967 – 1.01 0.281 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 0.974 0.8 – 1.19 0.797 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 0.976 0.87 – 1.09 0.673 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.934 0.735 – 1.19 0.58 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 0.98 0.95 – 1.01 0.211 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.01 0.992 – 1.03 0.3 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.921 0.815 – 1.04 0.184 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 0.929 0.821 – 1.05 0.243 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.879 0.696 – 1.11 0.281 74 756 all phecode
110.12 Althete's foot Infectious Diseases 0.909 0.767 – 1.08 0.267 141 1410 all phecode
112 Candidiasis Infectious Diseases 0.975 0.933 – 1.02 0.269 2126 21275 all phecode
117 Mycoses Infectious Diseases 1.05 0.928 – 1.19 0.432 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 1.01 0.865 – 1.18 0.888 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 0.878 0.7 – 1.1 0.261 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 0.865 0.677 – 1.11 0.247 69 689 all phecode
134 Helminthiases Infectious Diseases 0.901 0.75 – 1.08 0.27 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 0.892 0.731 – 1.09 0.264 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.01 0.876 – 1.16 0.92 205 2050 all phecode
145 Cancer of mouth Neoplasms 1.01 0.928 – 1.09 0.885 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 1.04 0.925 – 1.17 0.511 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.08 0.882 – 1.31 0.469 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 1.06 0.808 – 1.38 0.692 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1.02 0.936 – 1.1 0.712 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 1.02 0.897 – 1.16 0.763 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 1.03 0.911 – 1.17 0.614 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.973 0.742 – 1.27 0.84 57 570 all phecode
150 Cancer of esophagus Neoplasms 0.923 0.858 – 0.993 0.0314 762 7630 all phecode
151 Cancer of stomach Neoplasms 0.91 0.836 – 0.99 0.0284 569 5696 all phecode
153 Colorectal cancer Neoplasms 0.964 0.935 – 0.993 0.0162 4580 45799 all phecode
153.2 Colon cancer Neoplasms 0.965 0.93 – 1 0.0575 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.975 0.933 – 1.02 0.263 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.993 0.898 – 1.1 0.895 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.09 0.928 – 1.28 0.299 158 1580 all phecode
157 Pancreatic cancer Neoplasms 0.946 0.873 – 1.02 0.169 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.993 0.932 – 1.06 0.83 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.968 0.942 – 0.995 0.0204 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.935 0.805 – 1.09 0.376 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 1 0.868 – 1.16 0.965 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.12 0.961 – 1.3 0.15 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 0.988 0.761 – 1.28 0.931 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 0.984 0.946 – 1.02 0.4 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 0.997 0.955 – 1.04 0.897 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 0.95 0.861 – 1.05 0.313 437 4364 all phecode
170.1 Bone cancer Neoplasms 1.1 0.92 – 1.31 0.3 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 0.929 0.829 – 1.04 0.205 331 3303 all phecode
172 Skin cancer Neoplasms 0.997 0.98 – 1.02 0.761 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.947 0.91 – 0.985 0.00728 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 0.944 0.908 – 0.982 0.0043 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1 0.983 – 1.02 0.777 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.03 0.947 – 1.11 0.542 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.02 0.876 – 1.19 0.797 181 1818 all phecode
174 Breast cancer Neoplasms 1 0.982 – 1.02 1 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 1 0.982 – 1.02 0.985 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.997 0.978 – 1.02 0.717 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.05 0.871 – 1.26 0.613 115 1148 all phecode
175 Acquired absence of breast Neoplasms 1.02 0.978 – 1.06 0.36 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 1.02 0.976 – 1.07 0.375 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 0.945 0.835 – 1.07 0.372 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.02 0.975 – 1.07 0.38 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 0.924 0.873 – 0.978 0.00663 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 1.02 0.964 – 1.08 0.511 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.04 0.972 – 1.11 0.266 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.04 0.975 – 1.11 0.223 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.919 0.818 – 1.03 0.157 305 3049 all phecode
185 Cancer of prostate Neoplasms 0.998 0.972 – 1.03 0.892 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 0.939 0.853 – 1.03 0.204 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.01 0.798 – 1.28 0.917 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.91 0.806 – 1.03 0.126 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.974 0.807 – 1.18 0.785 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.01 0.98 – 1.04 0.492 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.01 0.946 – 1.07 0.854 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.01 0.948 – 1.07 0.778 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.979 0.762 – 1.26 0.868 66 660 all phecode
189.2 Cancer of bladder Neoplasms 0.997 0.956 – 1.04 0.891 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.995 0.952 – 1.04 0.823 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.877 0.738 – 1.04 0.133 144 1439 all phecode
190 Cancer of eye Neoplasms 0.966 0.83 – 1.12 0.655 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.974 0.901 – 1.05 0.501 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1 0.92 – 1.09 0.943 566 5650 all phecode
191.11 Cancer of brain Neoplasms 1.01 0.923 – 1.11 0.818 525 5240 all phecode
193 Thyroid cancer Neoplasms 0.956 0.856 – 1.07 0.416 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 0.822 0.667 – 1.01 0.0665 95 949 all phecode
195 Cancer, suspected or other Neoplasms 0.99 0.974 – 1.01 0.21 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 0.99 0.974 – 1.01 0.209 16267 159497 all phecode
197 Chemotherapy Neoplasms 1 0.991 – 1.02 0.519 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 0.992 0.971 – 1.01 0.442 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 0.999 0.971 – 1.03 0.934 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.972 0.931 – 1.01 0.192 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.02 0.965 – 1.07 0.542 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 0.981 0.943 – 1.02 0.334 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.953 0.888 – 1.02 0.176 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.02 0.976 – 1.07 0.368 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.842 0.723 – 0.98 0.0261 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 0.994 0.941 – 1.05 0.823 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 1.11 0.895 – 1.39 0.332 95 950 all phecode
200 Myeloproliferative disease Neoplasms 0.961 0.901 – 1.03 0.232 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 0.981 0.883 – 1.09 0.719 387 3867 all phecode
201 Hodgkin's disease Neoplasms 0.901 0.797 – 1.02 0.0999 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1 0.96 – 1.05 0.919 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1 0.956 – 1.05 0.892 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 1.03 0.923 – 1.15 0.612 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 0.968 0.889 – 1.05 0.455 581 5824 all phecode
204 Leukemia Neoplasms 0.963 0.916 – 1.01 0.145 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 0.922 0.846 – 1 0.0645 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.9 0.687 – 1.18 0.441 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.915 0.835 – 1 0.0573 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 0.977 0.888 – 1.07 0.628 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.971 0.87 – 1.09 0.607 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 0.991 0.837 – 1.17 0.921 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 0.928 0.85 – 1.01 0.0933 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 0.984 0.97 – 0.999 0.0317 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.987 0.924 – 1.06 0.711 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.993 0.965 – 1.02 0.622 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.895 0.802 – 0.998 0.0465 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.01 0.895 – 1.13 0.928 318 3187 all phecode
214 Lipoma Neoplasms 0.992 0.966 – 1.02 0.537 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1 0.971 – 1.03 0.944 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.07 1.01 – 1.14 0.0227 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 1.01 0.989 – 1.04 0.313 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.996 0.916 – 1.08 0.918 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 0.999 0.917 – 1.09 0.987 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 1 0.979 – 1.02 0.979 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 0.999 0.979 – 1.02 0.947 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.05 0.942 – 1.17 0.379 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 0.976 0.925 – 1.03 0.367 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.03 0.895 – 1.18 0.708 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 1.08 0.92 – 1.27 0.341 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.03 0.877 – 1.2 0.756 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 1.01 0.844 – 1.21 0.91 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 0.952 0.744 – 1.22 0.698 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.988 0.919 – 1.06 0.737 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.987 0.917 – 1.06 0.726 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.906 0.688 – 1.19 0.485 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.989 0.875 – 1.12 0.863 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.979 0.914 – 1.05 0.554 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.909 0.784 – 1.05 0.204 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.08 0.969 – 1.2 0.169 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.948 0.843 – 1.07 0.374 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.03 0.976 – 1.08 0.299 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.01 0.968 – 1.05 0.669 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.05 0.967 – 1.14 0.239 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 1 0.944 – 1.07 0.904 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.06 0.964 – 1.16 0.231 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.966 0.892 – 1.05 0.39 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.976 0.931 – 1.02 0.304 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 0.89 0.811 – 0.976 0.0137 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.06 0.858 – 1.3 0.607 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 0.848 0.715 – 1 0.057 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 0.989 0.973 – 1.01 0.215 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 0.986 0.927 – 1.05 0.651 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.887 0.723 – 1.09 0.253 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 0.988 0.971 – 1.01 0.176 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 0.903 0.801 – 1.02 0.093 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.915 0.796 – 1.05 0.205 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.938 0.814 – 1.08 0.369 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 0.957 0.865 – 1.06 0.4 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 0.999 0.984 – 1.01 0.849 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.987 0.949 – 1.03 0.524 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.902 0.79 – 1.03 0.126 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.03 0.809 – 1.3 0.838 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.99 0.9 – 1.09 0.844 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 1.05 0.891 – 1.23 0.577 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.999 0.984 – 1.01 0.888 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.952 0.781 – 1.16 0.628 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.02 0.882 – 1.18 0.792 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.988 0.925 – 1.05 0.711 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.01 0.922 – 1.11 0.834 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 0.959 0.887 – 1.04 0.285 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.967 0.854 – 1.09 0.592 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.964 0.872 – 1.07 0.47 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.905 0.76 – 1.08 0.259 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.03 0.92 – 1.15 0.641 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.996 0.941 – 1.05 0.894 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 1.02 0.957 – 1.09 0.499 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1 0.934 – 1.07 0.987 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1 0.931 – 1.08 0.968 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.917 0.775 – 1.09 0.314 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.989 0.914 – 1.07 0.777 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.05 0.909 – 1.22 0.495 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.02 0.833 – 1.25 0.852 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.977 0.861 – 1.11 0.712 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 1.03 0.835 – 1.27 0.778 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.951 0.81 – 1.12 0.542 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.987 0.91 – 1.07 0.746 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.08 0.925 – 1.25 0.339 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.979 0.802 – 1.2 0.836 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.25 0.993 – 1.57 0.0572 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.938 0.843 – 1.04 0.243 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.935 0.84 – 1.04 0.221 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 0.996 0.872 – 1.14 0.957 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.985 0.855 – 1.14 0.839 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 0.893 0.761 – 1.05 0.169 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.918 0.778 – 1.08 0.313 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.01 0.83 – 1.23 0.915 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.09 0.923 – 1.29 0.309 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.94 0.815 – 1.08 0.391 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 0.923 0.701 – 1.21 0.567 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 0.989 0.922 – 1.06 0.756 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 0.962 0.907 – 1.02 0.203 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.957 0.889 – 1.03 0.241 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.01 0.916 – 1.11 0.852 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.03 0.809 – 1.31 0.822 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.05 0.92 – 1.2 0.471 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 1.03 0.92 – 1.15 0.62 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.02 0.906 – 1.15 0.754 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1 0.883 – 1.14 0.97 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 0.938 0.808 – 1.09 0.401 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 0.947 0.78 – 1.15 0.578 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.29 1.02 – 1.64 0.0364 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.941 0.796 – 1.11 0.471 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.907 0.758 – 1.08 0.282 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.988 0.977 – 0.999 0.0355 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.988 0.977 – 0.999 0.0353 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.987 0.976 – 0.999 0.0307 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.956 0.736 – 1.24 0.738 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.896 0.767 – 1.05 0.168 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 0.929 0.811 – 1.06 0.291 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.961 0.929 – 0.994 0.0202 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 0.951 0.917 – 0.986 0.00617 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.917 0.753 – 1.12 0.389 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.03 0.942 – 1.12 0.566 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.05 0.962 – 1.15 0.267 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.03 0.982 – 1.07 0.239 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 1.01 0.936 – 1.1 0.739 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.06 0.957 – 1.18 0.256 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.04 0.976 – 1.1 0.245 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.09 0.929 – 1.27 0.302 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.01 0.981 – 1.03 0.682 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.02 0.985 – 1.05 0.287 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.04 0.917 – 1.19 0.519 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 0.984 0.938 – 1.03 0.511 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 0.983 0.92 – 1.05 0.612 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.12 1.06 – 1.18 9.63e-05 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.01 0.954 – 1.08 0.647 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 1.02 0.96 – 1.09 0.477 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 1.01 0.833 – 1.23 0.897 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 0.989 0.951 – 1.03 0.564 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 0.996 0.903 – 1.1 0.929 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 1 0.833 – 1.2 0.997 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 0.989 0.924 – 1.06 0.762 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.934 0.839 – 1.04 0.21 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.09 0.948 – 1.25 0.233 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.14 0.849 – 1.53 0.384 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 0.989 0.97 – 1.01 0.292 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 0.991 0.972 – 1.01 0.388 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 1.05 0.847 – 1.31 0.645 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.753 0.588 – 0.964 0.0247 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1 0.881 – 1.14 0.962 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 0.973 0.844 – 1.12 0.704 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.979 0.823 – 1.16 0.812 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 1.09 0.954 – 1.25 0.202 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 0.998 0.975 – 1.02 0.885 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1 0.976 – 1.02 0.994 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 0.957 0.87 – 1.05 0.371 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 0.999 0.939 – 1.06 0.962 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 0.999 0.938 – 1.06 0.97 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 0.985 0.914 – 1.06 0.689 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.941 0.809 – 1.09 0.428 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 1.11 0.956 – 1.29 0.168 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 0.996 0.761 – 1.3 0.975 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 0.998 0.847 – 1.18 0.984 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 0.953 0.732 – 1.24 0.718 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.07 0.857 – 1.34 0.546 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 0.839 0.708 – 0.994 0.0425 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.827 0.685 – 0.999 0.0489 103 1059 all phecode
284 Aplastic anemia Hematopoietic 1 0.908 – 1.1 0.98 435 4357 all phecode
285 Other anemias Hematopoietic 1.01 0.987 – 1.02 0.545 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1.03 0.914 – 1.17 0.6 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.02 0.944 – 1.1 0.63 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.972 0.881 – 1.07 0.578 414 4147 all phecode
286 Coagulation defects Hematopoietic 0.946 0.885 – 1.01 0.107 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 0.974 0.885 – 1.07 0.588 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 0.903 0.733 – 1.11 0.339 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.02 0.902 – 1.14 0.787 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 0.932 0.707 – 1.23 0.616 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.08 0.878 – 1.32 0.474 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.883 0.795 – 0.981 0.0201 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 0.978 0.929 – 1.03 0.388 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.904 0.757 – 1.08 0.267 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 0.853 0.645 – 1.13 0.266 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 0.985 0.935 – 1.04 0.584 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 1.02 0.924 – 1.13 0.683 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.26 0.99 – 1.6 0.0608 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 0.998 0.965 – 1.03 0.918 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 0.99 0.954 – 1.03 0.575 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 0.989 0.954 – 1.03 0.557 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 0.827 0.649 – 1.06 0.127 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 0.964 0.899 – 1.03 0.296 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.917 0.813 – 1.03 0.157 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 1.01 0.967 – 1.05 0.745 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 1.05 0.955 – 1.14 0.333 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 1 0.89 – 1.13 0.947 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 0.905 0.734 – 1.12 0.348 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1.02 0.977 – 1.07 0.325 1929 19281 all phecode
290.1 Dementias Mental Disorders 1.02 0.953 – 1.09 0.607 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 0.964 0.873 – 1.07 0.476 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 0.984 0.851 – 1.14 0.832 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.04 0.96 – 1.13 0.334 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 0.949 0.746 – 1.21 0.668 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.975 0.908 – 1.05 0.484 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.1 0.919 – 1.33 0.29 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.962 0.852 – 1.09 0.527 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 0.959 0.869 – 1.06 0.403 436 4376 all phecode
292 Neurological disorders Mental Disorders 1.01 0.979 – 1.04 0.548 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.966 0.916 – 1.02 0.204 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 1.01 0.871 – 1.18 0.857 190 1907 all phecode
292.3 Memory loss Mental Disorders 0.996 0.922 – 1.08 0.927 696 6978 all phecode
292.4 Altered mental status Mental Disorders 1.02 0.978 – 1.07 0.337 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 1.02 0.908 – 1.14 0.764 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 1.01 0.968 – 1.06 0.603 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.03 0.958 – 1.1 0.465 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.999 0.93 – 1.07 0.981 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 1.01 0.928 – 1.1 0.789 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 1.04 0.894 – 1.21 0.607 178 1780 all phecode
295.3 Psychosis Mental Disorders 0.924 0.787 – 1.08 0.335 169 1710 all phecode
296 Mood disorders Mental Disorders 1.01 0.987 – 1.02 0.585 12372 123822 all phecode
296.1 Bipolar Mental Disorders 1.05 0.987 – 1.12 0.122 1059 10599 all phecode
296.2 Depression Mental Disorders 1 0.985 – 1.02 0.728 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 0.955 0.859 – 1.06 0.395 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.03 0.918 – 1.15 0.638 311 3070 all phecode
300 Anxiety disorders Mental Disorders 1.01 0.987 – 1.04 0.367 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 1.01 0.985 – 1.04 0.414 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 0.938 0.793 – 1.11 0.455 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.02 0.939 – 1.1 0.704 707 7065 all phecode
300.13 Phobia Mental Disorders 1.01 0.921 – 1.11 0.845 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 1.03 0.872 – 1.22 0.707 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 0.921 0.688 – 1.23 0.581 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 0.996 0.835 – 1.19 0.969 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.926 0.765 – 1.12 0.427 113 1129 all phecode
301 Personality disorders Mental Disorders 1.02 0.912 – 1.14 0.728 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.01 0.841 – 1.22 0.89 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 0.954 0.848 – 1.07 0.439 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.04 0.947 – 1.14 0.411 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 1.04 0.934 – 1.16 0.461 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 1 0.839 – 1.2 0.958 123 1229 all phecode
304 Adjustment reaction Mental Disorders 1.09 0.964 – 1.23 0.175 293 2936 all phecode
305.2 Eating disorder Mental Disorders 1.01 0.815 – 1.25 0.943 90 900 all phecode
306 Other mental disorder Mental Disorders 1 0.99 – 1.02 0.681 28056 230087 all phecode
306.9 Tension headache Mental Disorders 0.988 0.882 – 1.11 0.832 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 0.884 0.689 – 1.13 0.332 76 770 all phecode
313.3 Autism Mental Disorders 0.934 0.697 – 1.25 0.647 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 1.03 0.924 – 1.15 0.59 351 3517 all phecode
315.1 Learning disorder Mental Disorders 0.965 0.821 – 1.13 0.662 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 0.945 0.766 – 1.17 0.602 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 1.01 0.982 – 1.04 0.507 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.05 0.813 – 1.36 0.707 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 1 0.981 – 1.02 0.957 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 0.992 0.97 – 1.01 0.446 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 0.989 0.922 – 1.06 0.763 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 0.983 0.968 – 0.997 0.0217 19359 185465 all phecode
320 Meningitis Neurological 0.964 0.876 – 1.06 0.458 444 4447 all phecode
323 Encephalitis Neurological 1.08 0.962 – 1.2 0.199 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 1.19 0.943 – 1.51 0.14 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.03 0.915 – 1.16 0.606 292 2916 all phecode
327 Sleep disorders Neurological 1.03 0.967 – 1.09 0.393 1164 11659 all phecode
327.3 Sleep apnea Neurological 0.977 0.947 – 1.01 0.139 4428 44318 all phecode
327.4 Insomnia Neurological 1.04 0.885 – 1.22 0.646 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 1.13 0.949 – 1.35 0.169 136 1390 all phecode
331 Other cerebral degenerations Neurological 1.04 0.977 – 1.1 0.223 1142 11416 all phecode
331.1 Hydrocephalus Neurological 1.01 0.923 – 1.11 0.815 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 1.08 0.98 – 1.19 0.119 430 4298 all phecode
332 Parkinson's disease Neurological 0.985 0.926 – 1.05 0.63 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.01 0.94 – 1.08 0.863 894 8954 all phecode
333.1 Essential tremor Neurological 1.02 0.891 – 1.18 0.746 216 2157 all phecode
333.2 Myoclonus Neurological 1.17 0.949 – 1.43 0.143 96 958 all phecode
333.4 Torsion dystonia Neurological 1.03 0.903 – 1.17 0.669 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 0.991 0.944 – 1.04 0.702 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 1.08 0.895 – 1.3 0.427 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 1.03 0.903 – 1.17 0.681 245 2446 all phecode
335 Multiple sclerosis Neurological 0.971 0.918 – 1.03 0.296 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 1.02 0.9 – 1.15 0.795 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 0.885 0.701 – 1.12 0.303 72 719 all phecode
338 Pain Neurological 0.991 0.921 – 1.07 0.812 768 7692 all phecode
338.1 Acute pain Neurological 0.929 0.838 – 1.03 0.16 394 3937 all phecode
338.2 Chronic pain Neurological 1.03 0.931 – 1.15 0.531 380 3817 all phecode
339 Other headache syndromes Neurological 0.99 0.968 – 1.01 0.413 7819 78241 all phecode
340 Migraine Neurological 0.981 0.943 – 1.02 0.318 2860 28602 all phecode
340.1 Migrain with aura Neurological 1.06 0.912 – 1.22 0.469 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.915 0.804 – 1.04 0.173 252 2535 all phecode
342 Hemiplegia Neurological 0.959 0.91 – 1.01 0.126 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 0.862 0.723 – 1.03 0.097 145 1450 all phecode
344 Other paralytic syndromes Neurological 0.976 0.9 – 1.06 0.549 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.992 0.964 – 1.02 0.586 5023 50270 all phecode
345.1 Epilepsy Neurological 0.975 0.909 – 1.05 0.472 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 0.932 0.846 – 1.03 0.151 439 4385 all phecode
345.12 Partial epilepsy Neurological 0.971 0.858 – 1.1 0.638 277 2776 all phecode
345.3 Convulsions Neurological 0.979 0.938 – 1.02 0.345 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.01 0.855 – 1.2 0.898 144 1438 all phecode
348 Other conditions of brain Neurological 0.97 0.901 – 1.05 0.43 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 0.929 0.817 – 1.06 0.258 268 2678 all phecode
348.4 Cerebral cysts Neurological 0.859 0.718 – 1.03 0.0947 133 1350 all phecode
348.7 Coma Neurological 1 0.9 – 1.12 0.948 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.08 0.948 – 1.23 0.246 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 0.996 0.899 – 1.1 0.932 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.984 0.88 – 1.1 0.772 342 3414 all phecode
350 Abnormal movement Neurological 0.996 0.957 – 1.04 0.861 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 1.05 0.98 – 1.13 0.162 887 8852 all phecode
350.2 Abnormality of gait Neurological 0.976 0.927 – 1.03 0.358 1596 15969 all phecode
350.3 Lack of coordination Neurological 1.01 0.903 – 1.12 0.898 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.01 0.776 – 1.32 0.928 54 540 all phecode
351 Other peripheral nerve disorders Neurological 0.989 0.971 – 1.01 0.227 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 1.02 0.964 – 1.08 0.498 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.933 0.848 – 1.03 0.149 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.04 0.974 – 1.12 0.224 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 0.99 0.932 – 1.05 0.744 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 1 0.826 – 1.21 0.999 114 1138 all phecode
353.2 Nerve root lesions Neurological 0.869 0.673 – 1.12 0.282 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 0.978 0.83 – 1.15 0.786 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.04 0.982 – 1.1 0.191 1361 13648 all phecode
358 Myoneural disorders Neurological 1.02 0.886 – 1.17 0.817 211 2109 all phecode
358.1 Myasthenia gravis Neurological 1.02 0.889 – 1.18 0.735 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 0.928 0.843 – 1.02 0.133 465 4646 all phecode
359.1 Muscular dystrophies Neurological 0.95 0.784 – 1.15 0.6 122 1219 all phecode
359.2 Myopathy Neurological 0.917 0.822 – 1.02 0.12 360 3597 all phecode
360 Disorders of the globe Sense Organs 1.02 0.909 – 1.14 0.77 337 3367 all phecode
360.2 Progressive myopia Sense Organs 0.958 0.842 – 1.09 0.509 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 0.995 0.96 – 1.03 0.782 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.982 0.93 – 1.04 0.523 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.803 0.628 – 1.03 0.0806 68 680 all phecode
362 Other retinal disorders Sense Organs 0.99 0.958 – 1.02 0.539 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 0.994 0.951 – 1.04 0.778 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 0.993 0.951 – 1.04 0.766 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 0.927 0.789 – 1.09 0.359 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 0.926 0.755 – 1.14 0.463 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.01 0.94 – 1.08 0.819 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 1 0.862 – 1.17 0.968 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 1.01 0.808 – 1.26 0.932 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.13 0.937 – 1.37 0.199 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.91 0.779 – 1.06 0.238 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 0.833 0.651 – 1.07 0.147 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.02 0.94 – 1.1 0.658 647 6485 all phecode
364.1 Corneal opacity Sense Organs 0.873 0.703 – 1.08 0.219 90 910 all phecode
364.2 Corneal edema Sense Organs 0.918 0.733 – 1.15 0.457 79 800 all phecode
364.4 Corneal degenerations Sense Organs 0.911 0.789 – 1.05 0.206 201 2017 all phecode
364.41 Keratoconus Sense Organs 0.822 0.66 – 1.02 0.0806 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 1 0.868 – 1.16 0.987 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.934 0.763 – 1.14 0.509 100 1000 all phecode
365 Glaucoma Sense Organs 1.01 0.978 – 1.04 0.596 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 0.969 0.91 – 1.03 0.339 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 0.972 0.912 – 1.04 0.381 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 0.995 0.921 – 1.07 0.89 698 6996 all phecode
366 Cataract Sense Organs 0.986 0.972 – 1 0.0652 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 1.18 0.927 – 1.51 0.175 69 700 all phecode
366.2 Senile cataract Sense Organs 0.994 0.971 – 1.02 0.578 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 0.971 0.791 – 1.19 0.782 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.986 0.946 – 1.03 0.504 2408 24092 all phecode
367.1 Myopia Sense Organs 0.987 0.931 – 1.05 0.652 1251 12519 all phecode
367.2 Astigmatism Sense Organs 0.859 0.739 – 0.998 0.0469 190 1899 all phecode
367.8 Hypermetropia Sense Organs 1.05 0.924 – 1.19 0.46 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 1.01 0.935 – 1.09 0.832 719 7198 all phecode
368 Visual disturbances Sense Organs 1.02 0.979 – 1.06 0.377 2962 29648 all phecode
368.1 Amblyopia Sense Organs 0.969 0.887 – 1.06 0.491 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.03 0.956 – 1.11 0.437 727 7288 all phecode
368.3 Anisometropia Sense Organs 1.06 0.9 – 1.25 0.473 154 1548 all phecode
368.4 Visual field defects Sense Organs 1.15 1.03 – 1.29 0.0176 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 1.08 0.991 – 1.17 0.0806 612 6115 all phecode
369 Infection of the eye Sense Organs 1.07 0.981 – 1.17 0.123 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 1.11 0.918 – 1.34 0.284 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 1.07 0.926 – 1.24 0.358 213 2128 all phecode
370 Keratitis Sense Organs 1.11 0.978 – 1.25 0.107 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 1.05 0.88 – 1.24 0.61 141 1408 all phecode
371 Inflammation of the eye Sense Organs 1.01 0.975 – 1.05 0.528 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.966 0.88 – 1.06 0.471 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 1.01 0.967 – 1.05 0.7 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 0.99 0.919 – 1.07 0.788 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 0.987 0.961 – 1.01 0.355 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 0.956 0.897 – 1.02 0.155 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 1 0.957 – 1.05 0.852 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 1.01 0.969 – 1.06 0.589 2204 22031 all phecode
375.2 Epiphora Sense Organs 1 0.937 – 1.07 0.918 898 8969 all phecode
376 Disorders of the orbit Sense Organs 1.17 0.935 – 1.46 0.171 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.954 0.857 – 1.06 0.385 361 3618 all phecode
377.1 Optic atrophy Sense Organs 0.938 0.715 – 1.23 0.643 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.911 0.766 – 1.08 0.29 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 1.01 0.96 – 1.07 0.622 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.99 0.924 – 1.06 0.766 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.967 0.842 – 1.11 0.632 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 1.09 0.967 – 1.24 0.155 275 2755 all phecode
379 Other disorders of eye Sense Organs 0.986 0.954 – 1.02 0.416 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 0.995 0.942 – 1.05 0.868 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.963 0.918 – 1.01 0.124 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.04 0.813 – 1.32 0.778 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.04 0.94 – 1.15 0.439 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.18 1.01 – 1.38 0.0355 169 1690 all phecode
380 Disorders of external ear Sense Organs 1.04 0.957 – 1.13 0.369 642 6413 all phecode
380.1 Otitis externa Sense Organs 1.01 0.923 – 1.11 0.806 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 0.971 0.873 – 1.08 0.591 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.995 0.952 – 1.04 0.822 2150 21493 all phecode
381.1 Otitis media Sense Organs 1 0.956 – 1.05 0.873 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1 0.935 – 1.08 0.935 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 1.09 0.937 – 1.27 0.264 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 0.906 0.777 – 1.06 0.208 171 1709 all phecode
381.9 Otorrhea Sense Organs 0.85 0.752 – 0.96 0.00901 281 2807 all phecode
382 Otalgia Sense Organs 1.02 0.91 – 1.15 0.717 308 3084 all phecode
383 Otosclerosis Sense Organs 0.966 0.859 – 1.09 0.557 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 0.969 0.916 – 1.03 0.279 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 0.959 0.9 – 1.02 0.192 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 0.976 0.907 – 1.05 0.522 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 0.95 0.873 – 1.03 0.226 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.11 0.973 – 1.27 0.121 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.03 0.978 – 1.08 0.28 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 0.996 0.915 – 1.08 0.927 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 1.04 0.937 – 1.16 0.448 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 1 0.932 – 1.08 0.923 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 0.993 0.963 – 1.02 0.646 4582 45806 all phecode
388 Other disorders of ear Sense Organs 1.14 0.986 – 1.31 0.0768 202 2017 all phecode
389 Hearing loss Sense Organs 0.996 0.965 – 1.03 0.817 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 0.953 0.867 – 1.05 0.319 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 1.03 0.933 – 1.13 0.572 450 4497 all phecode
389.4 Tinnitus Sense Organs 0.994 0.907 – 1.09 0.89 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 0.982 0.953 – 1.01 0.221 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 0.969 0.934 – 1.01 0.102 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 1.04 0.977 – 1.1 0.238 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 0.977 0.917 – 1.04 0.464 1058 10566 all phecode
395 Heart valve disorders Circulatory System 0.982 0.951 – 1.01 0.263 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.98 0.943 – 1.02 0.292 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.01 0.89 – 1.14 0.885 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.13 0.927 – 1.38 0.222 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.899 0.733 – 1.1 0.308 97 970 all phecode
395.6 Heart valve replaced Circulatory System 0.992 0.94 – 1.05 0.759 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 1.03 0.965 – 1.1 0.397 1048 10468 all phecode
401 Hypertension Circulatory System 0.975 0.967 – 0.983 4.78e-09 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 0.975 0.967 – 0.983 3.11e-09 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 0.992 0.947 – 1.04 0.741 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 1.01 0.91 – 1.13 0.824 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 0.993 0.942 – 1.05 0.779 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 1.24 1.05 – 1.47 0.0136 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1 0.95 – 1.06 0.94 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 0.988 0.977 – 1 0.0583 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.984 0.956 – 1.01 0.263 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 0.984 0.965 – 1 0.0865 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 0.986 0.97 – 1 0.0979 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 0.993 0.979 – 1.01 0.354 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.946 0.876 – 1.02 0.162 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.993 0.977 – 1.01 0.424 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1 0.944 – 1.06 0.978 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 0.989 0.943 – 1.04 0.651 1823 18228 all phecode
414.2 ASCVD Circulatory System 1.04 0.822 – 1.31 0.746 72 719 all phecode
415 Pulmonary heart disease Circulatory System 0.995 0.965 – 1.03 0.749 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.955 0.75 – 1.22 0.709 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.962 0.886 – 1.04 0.358 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 0.976 0.886 – 1.08 0.626 448 4475 all phecode
416 Cardiomegaly Circulatory System 0.971 0.933 – 1.01 0.145 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 0.987 0.975 – 0.999 0.0385 28599 270106 all phecode
418.1 Precordial pain Circulatory System 0.999 0.965 – 1.03 0.957 3551 35541 all phecode
420 Carditis Circulatory System 0.99 0.946 – 1.03 0.648 2106 21053 all phecode
420.1 Myocarditis Circulatory System 1 0.836 – 1.2 0.991 127 1267 all phecode
420.2 Pericarditis Circulatory System 0.997 0.942 – 1.05 0.91 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 1.02 0.89 – 1.17 0.763 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 1.05 0.866 – 1.27 0.628 113 1129 all phecode
420.3 Endocarditis Circulatory System 0.989 0.916 – 1.07 0.788 719 7194 all phecode
425 Cardiomyopathy Circulatory System 0.994 0.939 – 1.05 0.843 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.992 0.936 – 1.05 0.786 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.932 0.777 – 1.12 0.45 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.887 0.754 – 1.04 0.149 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 1.07 0.816 – 1.39 0.641 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 0.98 0.956 – 1 0.114 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 0.996 0.952 – 1.04 0.847 2114 21162 all phecode
426.21 First degree AV block Circulatory System 0.987 0.924 – 1.05 0.684 986 9867 all phecode
426.23 Second degree AV block Circulatory System 1.01 0.922 – 1.12 0.769 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 0.982 0.903 – 1.07 0.667 587 5868 all phecode
426.25 Other heart block Circulatory System 1.03 0.862 – 1.23 0.734 131 1318 all phecode
426.3 Bundle branch block Circulatory System 0.97 0.936 – 1.01 0.0984 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 0.979 0.928 – 1.03 0.438 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 0.964 0.918 – 1.01 0.146 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.885 0.774 – 1.01 0.0718 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.05 0.805 – 1.36 0.736 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.968 0.929 – 1.01 0.124 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.975 0.934 – 1.02 0.245 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 0.994 0.981 – 1.01 0.386 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 0.992 0.957 – 1.03 0.676 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.974 0.934 – 1.02 0.224 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1 0.939 – 1.07 0.911 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 1 0.986 – 1.02 0.701 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.985 0.95 – 1.02 0.411 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.962 0.906 – 1.02 0.201 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1.01 0.902 – 1.13 0.876 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 0.959 0.899 – 1.02 0.216 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.906 0.847 – 0.969 0.0039 952 9541 all phecode
427.6 Premature beats Circulatory System 1.03 0.946 – 1.13 0.476 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 0.87 0.721 – 1.05 0.144 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 0.961 0.92 – 1 0.0746 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.952 0.861 – 1.05 0.344 402 4029 all phecode
427.9 Palpitations Circulatory System 0.999 0.966 – 1.03 0.958 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.03 0.998 – 1.05 0.0724 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1 0.96 – 1.05 0.874 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 1.03 0.995 – 1.06 0.0962 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.03 0.952 – 1.11 0.488 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 1.15 0.896 – 1.48 0.268 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.979 0.896 – 1.07 0.642 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.15 0.998 – 1.33 0.0541 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 1.01 0.965 – 1.06 0.635 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.04 0.974 – 1.12 0.224 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 0.997 0.926 – 1.07 0.94 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 1.02 0.905 – 1.16 0.711 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 0.999 0.977 – 1.02 0.914 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.02 0.962 – 1.08 0.49 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 0.966 0.843 – 1.11 0.625 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.998 0.967 – 1.03 0.895 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.985 0.937 – 1.04 0.554 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 0.978 0.942 – 1.02 0.264 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 0.984 0.941 – 1.03 0.476 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 1.02 0.916 – 1.13 0.773 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.921 0.87 – 0.975 0.00478 1279 12783 all phecode
440 Atherosclerosis Circulatory System 1.02 0.966 – 1.08 0.466 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.15 0.95 – 1.39 0.151 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.02 0.954 – 1.1 0.507 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 0.931 0.824 – 1.05 0.252 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 1.06 0.973 – 1.15 0.189 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.01 0.896 – 1.15 0.832 283 2827 all phecode
442 Other aneurysm Circulatory System 1.03 0.982 – 1.08 0.235 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 1.02 0.967 – 1.08 0.467 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.999 0.935 – 1.07 0.984 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.09 0.891 – 1.33 0.41 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.937 0.802 – 1.1 0.416 169 1696 all phecode
442.4 Arterial dissection Circulatory System 1.3 0.998 – 1.7 0.0522 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 1.13 0.971 – 1.31 0.116 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 1.01 0.981 – 1.05 0.4 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 1.02 0.955 – 1.08 0.622 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.06 0.954 – 1.18 0.283 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.02 0.984 – 1.05 0.308 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.02 0.981 – 1.06 0.295 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 0.999 0.934 – 1.07 0.967 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.01 0.926 – 1.1 0.833 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 0.998 0.929 – 1.07 0.968 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 0.937 0.806 – 1.09 0.402 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 1.06 0.958 – 1.18 0.247 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 0.932 0.816 – 1.06 0.298 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 0.983 0.929 – 1.04 0.547 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 0.979 0.913 – 1.05 0.542 868 8712 all phecode
448 Disease of capillaries Circulatory System 1.01 0.851 – 1.2 0.906 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.935 0.866 – 1.01 0.0906 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 0.992 0.96 – 1.03 0.638 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 0.992 0.959 – 1.03 0.635 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.955 0.875 – 1.04 0.3 564 5645 all phecode
454 Varicose veins Circulatory System 1.01 0.993 – 1.03 0.215 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1.01 0.996 – 1.03 0.129 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.989 0.911 – 1.07 0.791 624 6325 all phecode
455 Hemorrhoids Circulatory System 1 0.991 – 1.02 0.492 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.18 1.01 – 1.37 0.0362 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.07 0.867 – 1.32 0.533 97 967 all phecode
458 Hypotension Circulatory System 1.02 0.989 – 1.04 0.256 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 0.945 0.894 – 0.999 0.0479 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 0.869 0.76 – 0.994 0.041 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 1.04 1 – 1.08 0.0323 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 0.994 0.978 – 1.01 0.451 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 1.24 1.04 – 1.47 0.0144 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 0.993 0.977 – 1.01 0.375 16103 159422 all phecode
464 Acute sinusitis Respiratory 0.983 0.851 – 1.14 0.82 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.944 0.904 – 0.985 0.00787 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 0.936 0.872 – 1 0.0656 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.794 0.677 – 0.932 0.00482 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.02 0.994 – 1.06 0.12 4654 46553 all phecode
471 Nasal polyps Respiratory 1 0.968 – 1.04 0.87 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.02 0.957 – 1.09 0.502 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 1.02 0.981 – 1.06 0.309 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 1.03 0.848 – 1.26 0.739 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.938 0.826 – 1.06 0.319 264 2647 all phecode
473.4 Voice disturbance Respiratory 1.01 0.953 – 1.08 0.654 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 0.979 0.932 – 1.03 0.395 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 0.968 0.887 – 1.06 0.467 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.968 0.91 – 1.03 0.301 1122 11199 all phecode
475 Chronic sinusitis Respiratory 1 0.962 – 1.04 0.925 2589 25882 all phecode
476 Allergic rhinitis Respiratory 0.971 0.912 – 1.03 0.352 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 0.982 0.942 – 1.02 0.403 2447 24452 all phecode
478 Throat pain Respiratory 0.888 0.8 – 0.985 0.0242 377 3789 all phecode
479 Other upper respiratory disease Respiratory 1.02 0.986 – 1.05 0.278 4074 40737 all phecode
480 Pneumonia Respiratory 0.995 0.975 – 1.02 0.652 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 0.981 0.957 – 1.01 0.144 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 0.993 0.967 – 1.02 0.615 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.15 0.928 – 1.43 0.2 93 929 all phecode
480.2 Viral pneumonia Respiratory 1.04 0.822 – 1.32 0.737 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.04 0.836 – 1.28 0.751 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.978 0.909 – 1.05 0.542 794 7951 all phecode
481 Influenza Respiratory 0.923 0.825 – 1.03 0.164 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.01 0.875 – 1.17 0.853 193 1930 all phecode
495 Asthma Respiratory 0.996 0.983 – 1.01 0.525 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 1.04 0.909 – 1.18 0.587 250 2510 all phecode
496 Chronic airway obstruction Respiratory 1 0.983 – 1.02 0.787 10424 101546 all phecode
496.1 Emphysema Respiratory 0.991 0.944 – 1.04 0.714 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 1 0.965 – 1.04 0.889 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1 0.961 – 1.04 0.995 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 0.976 0.931 – 1.02 0.323 1885 18859 all phecode
497 Bronchitis Respiratory 0.889 0.818 – 0.965 0.00497 626 6267 all phecode
500 Lung disease due to external agents Respiratory 1.03 0.932 – 1.14 0.559 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.04 0.831 – 1.31 0.719 79 784 all phecode
500.2 Pneumoconiosis Respiratory 1.06 0.935 – 1.21 0.344 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 0.994 0.917 – 1.08 0.892 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.928 0.868 – 0.992 0.0284 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 0.93 0.849 – 1.02 0.12 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.946 0.845 – 1.06 0.331 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 1 0.773 – 1.3 0.988 61 610 all phecode
506 Empyema and pneumothorax Respiratory 1.07 1.01 – 1.14 0.0312 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 0.995 0.97 – 1.02 0.726 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.972 0.929 – 1.02 0.232 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.967 0.928 – 1.01 0.101 2599 26031 all phecode
509.1 Respiratory failure Respiratory 0.978 0.934 – 1.02 0.327 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 0.993 0.946 – 1.04 0.774 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 1.04 0.877 – 1.23 0.647 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.885 0.798 – 0.982 0.0207 386 3863 all phecode
510 Other diseases of lung Respiratory 1.01 0.937 – 1.09 0.787 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 0.999 0.978 – 1.02 0.947 9031 90349 all phecode
512.1 Wheezing Respiratory 1.02 0.889 – 1.18 0.755 220 2196 all phecode
512.2 Painful respiration Respiratory 1.15 0.998 – 1.33 0.0542 207 2075 all phecode
512.7 Shortness of breath Respiratory 0.999 0.973 – 1.03 0.947 5842 58498 all phecode
512.8 Cough Respiratory 1.02 0.982 – 1.06 0.294 2866 28642 all phecode
512.9 Other dyspnea Respiratory 0.943 0.881 – 1.01 0.0917 914 9124 all phecode
513 Respiratory abnormalities Respiratory 0.954 0.879 – 1.04 0.261 611 6112 all phecode
513.3 Hypoventilation Respiratory 1.18 0.945 – 1.48 0.143 83 830 all phecode
513.4 Hyperventilation Respiratory 0.931 0.823 – 1.05 0.252 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 0.89 0.755 – 1.05 0.163 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 0.99 0.95 – 1.03 0.624 2465 24673 all phecode
516 Abnormal sputum Respiratory 1.01 0.964 – 1.05 0.713 2132 21335 all phecode
516.1 Hemoptysis Respiratory 1.01 0.964 – 1.06 0.708 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.997 0.976 – 1.02 0.783 9366 93681 all phecode
519.2 Respiratory complications Respiratory 0.989 0.884 – 1.11 0.855 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.996 0.974 – 1.02 0.707 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.971 0.864 – 1.09 0.625 303 3049 all phecode
520 Disorders of tooth development Digestive 1.01 0.969 – 1.06 0.547 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.932 0.709 – 1.23 0.615 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 0.991 0.95 – 1.03 0.674 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 1.01 0.972 – 1.05 0.65 3016 30245 all phecode
521.1 Dental caries Digestive 1.01 0.973 – 1.05 0.591 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.02 0.967 – 1.07 0.535 1774 17750 all phecode
522.5 Periapical abscess Digestive 1.01 0.954 – 1.08 0.668 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 1 0.953 – 1.05 0.923 1681 16812 all phecode
523.1 Gingivitis Digestive 1.08 0.89 – 1.31 0.434 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 0.996 0.938 – 1.06 0.897 1165 11650 all phecode
523.31 Acute periodontitis Digestive 0.992 0.916 – 1.07 0.846 666 6667 all phecode
523.32 Chronic periodontitis Digestive 0.984 0.901 – 1.07 0.713 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.02 0.911 – 1.14 0.728 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.996 0.886 – 1.12 0.942 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.945 0.908 – 0.984 0.00562 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.878 0.691 – 1.12 0.288 72 720 all phecode
526 Diseases of the jaws Digestive 1.02 0.952 – 1.09 0.595 928 9279 all phecode
526.1 Cysts of the jaws Digestive 1.04 0.927 – 1.16 0.521 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.08 0.844 – 1.39 0.527 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 0.991 0.867 – 1.13 0.893 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1 0.874 – 1.14 0.999 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.949 0.776 – 1.16 0.614 110 1098 all phecode
526.9 Jaw disease NOS Digestive 1 0.877 – 1.15 0.968 233 2329 all phecode
527 Diseases of the salivary glands Digestive 1 0.925 – 1.08 0.984 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 0.97 0.781 – 1.21 0.786 84 838 all phecode
527.2 Sialoadenitis Digestive 1.02 0.915 – 1.14 0.729 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 0.941 0.719 – 1.23 0.654 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.12 0.926 – 1.35 0.247 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.01 0.981 – 1.05 0.402 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 1.02 0.927 – 1.12 0.689 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.03 0.927 – 1.14 0.582 389 3884 all phecode
528.12 Oral aphthae Digestive 1.04 0.825 – 1.3 0.763 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.13 0.972 – 1.32 0.111 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 0.975 0.811 – 1.17 0.788 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 1.01 0.824 – 1.25 0.898 94 940 all phecode
528.5 Diseases of lips Digestive 0.973 0.898 – 1.05 0.499 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 0.987 0.879 – 1.11 0.826 308 3079 all phecode
528.7 Sialolithiasis Digestive 0.99 0.882 – 1.11 0.865 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 0.967 0.912 – 1.03 0.263 1232 12312 all phecode
529.1 Glossitis Digestive 1.01 0.894 – 1.14 0.904 299 2986 all phecode
530 Diseases of esophagus Digestive 0.999 0.987 – 1.01 0.813 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 0.999 0.987 – 1.01 0.871 31253 272429 all phecode
530.11 GERD Digestive 0.994 0.98 – 1.01 0.353 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 1.02 0.991 – 1.05 0.184 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 1 0.983 – 1.02 0.744 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.962 0.916 – 1.01 0.133 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.01 0.964 – 1.06 0.644 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 0.954 0.879 – 1.03 0.252 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.891 0.756 – 1.05 0.171 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.891 0.796 – 0.996 0.0431 341 3416 all phecode
530.9 Heartburn Digestive 0.976 0.933 – 1.02 0.287 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.984 0.96 – 1.01 0.181 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.973 0.898 – 1.05 0.497 637 6374 all phecode
531.2 Gastric ulcer Digestive 0.981 0.95 – 1.01 0.241 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 1 0.966 – 1.04 0.879 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 0.95 0.86 – 1.05 0.307 427 4268 all phecode
532 Dysphagia Digestive 0.992 0.967 – 1.02 0.531 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 0.991 0.978 – 1 0.131 28078 261548 all phecode
535.1 Acute gastritis Digestive 1.04 0.978 – 1.1 0.22 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 1.02 0.921 – 1.14 0.66 370 3687 all phecode
535.6 Duodenitis Digestive 0.985 0.963 – 1.01 0.222 7592 75928 all phecode
535.8 Other specified gastritis Digestive 0.989 0.967 – 1.01 0.346 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.999 0.83 – 1.2 0.993 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.93 0.819 – 1.05 0.257 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 0.983 0.949 – 1.02 0.35 3391 33907 all phecode
540 Appendiceal conditions Digestive 0.99 0.954 – 1.03 0.589 3088 30890 all phecode
540.1 Appendicitis Digestive 0.993 0.956 – 1.03 0.717 2895 28963 all phecode
540.11 Acute appendicitis Digestive 0.991 0.951 – 1.03 0.655 2601 26019 all phecode
550 Abdominal hernia Digestive 1 0.993 – 1.01 0.542 45429 282640 all phecode
550.1 Inguinal hernia Digestive 1.01 0.992 – 1.03 0.307 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 1 0.988 – 1.01 0.872 26494 238953 all phecode
550.3 Femoral hernia Digestive 0.965 0.891 – 1.05 0.384 651 6504 all phecode
550.4 Umbilical hernia Digestive 0.997 0.964 – 1.03 0.845 3705 37072 all phecode
550.5 Ventral hernia Digestive 0.992 0.958 – 1.03 0.658 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.02 0.99 – 1.05 0.19 4444 44442 all phecode
555.1 Regional enteritis Digestive 0.993 0.945 – 1.04 0.768 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 1.03 0.992 – 1.07 0.13 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 0.983 0.902 – 1.07 0.705 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 1.03 0.964 – 1.09 0.405 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 1.05 0.967 – 1.14 0.251 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.957 0.85 – 1.08 0.471 299 2987 all phecode
557.1 Celiac disease Digestive 0.882 0.84 – 0.925 3.28e-07 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 1.02 1 – 1.03 0.0411 15492 155105 all phecode
559 Ileostomy status Digestive 0.972 0.924 – 1.02 0.272 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 0.986 0.955 – 1.02 0.411 3936 39337 all phecode
560.1 Paralytic ileus Digestive 1.04 0.955 – 1.14 0.342 523 5231 all phecode
560.2 Impaction of intestine Digestive 0.971 0.855 – 1.1 0.647 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.02 0.95 – 1.09 0.595 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 0.981 0.947 – 1.02 0.286 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 0.996 0.98 – 1.01 0.634 15772 157686 all phecode
561.1 Diarrhea Digestive 0.951 0.866 – 1.04 0.296 466 4653 all phecode
561.2 Flatulence Digestive 0.97 0.923 – 1.02 0.236 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 0.988 0.975 – 1 0.0593 26714 211692 all phecode
562.1 Diverticulosis Digestive 0.988 0.975 – 1 0.0598 26672 211642 all phecode
563 Constipation Digestive 0.993 0.973 – 1.01 0.492 10314 103140 all phecode
564 Functional digestive disorders Digestive 0.994 0.981 – 1.01 0.43 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 1 0.974 – 1.03 0.939 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.01 0.965 – 1.07 0.566 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 0.993 0.976 – 1.01 0.382 15186 151648 all phecode
565 Anal and rectal conditions Digestive 0.996 0.979 – 1.01 0.647 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 0.994 0.971 – 1.02 0.635 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 1.03 0.964 – 1.1 0.366 929 9293 all phecode
568 Other disorders of peritoneum Digestive 1.01 0.976 – 1.05 0.522 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.01 0.97 – 1.04 0.732 3101 30987 all phecode
569 Other disorders of intestine Digestive 0.994 0.963 – 1.03 0.696 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.9 0.759 – 1.07 0.222 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 1.04 0.952 – 1.15 0.358 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 0.985 0.948 – 1.02 0.423 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 0.984 0.936 – 1.03 0.526 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.742 0.613 – 0.898 0.00221 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 1.03 0.906 – 1.17 0.662 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.996 0.933 – 1.06 0.914 976 9804 all phecode
571.81 Portal hypertension Digestive 0.959 0.878 – 1.05 0.346 528 5285 all phecode
572 Ascites (non malignant) Digestive 0.99 0.939 – 1.04 0.694 1544 15454 all phecode
573 Other disorders of liver Digestive 0.995 0.944 – 1.05 0.85 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 1.13 0.925 – 1.38 0.229 96 960 all phecode
573.3 Hepatomegaly Digestive 1.02 0.907 – 1.15 0.724 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 1.01 0.946 – 1.08 0.709 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 0.979 0.945 – 1.01 0.226 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.03 0.893 – 1.18 0.713 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 0.999 0.982 – 1.02 0.864 15607 156123 all phecode
574.1 Cholelithiasis Digestive 0.994 0.977 – 1.01 0.532 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.979 0.929 – 1.03 0.431 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 0.995 0.967 – 1.02 0.713 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 1 0.963 – 1.04 0.909 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.998 0.959 – 1.04 0.906 2748 27523 all phecode
575 Other biliary tract disease Digestive 0.988 0.956 – 1.02 0.48 3867 38724 all phecode
575.1 Cholangitis Digestive 0.993 0.906 – 1.09 0.877 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 0.973 0.903 – 1.05 0.465 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.929 0.844 – 1.02 0.128 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 1.03 0.972 – 1.09 0.334 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 0.955 0.896 – 1.02 0.16 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.05 0.938 – 1.17 0.413 348 3488 all phecode
577 Diseases of pancreas Digestive 1.01 0.974 – 1.05 0.512 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 1.01 0.964 – 1.06 0.68 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 0.901 0.823 – 0.986 0.0232 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.01 0.909 – 1.13 0.827 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 1.01 1 – 1.03 0.0428 20626 206278 all phecode
578.1 Hematemesis Digestive 0.968 0.924 – 1.01 0.165 1958 19564 all phecode
578.2 Blood in stool Digestive 1.02 0.977 – 1.06 0.418 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.02 1 – 1.04 0.0181 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.994 0.967 – 1.02 0.688 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.975 0.926 – 1.03 0.348 1548 15498 all phecode
579.2 Splenomegaly Digestive 0.994 0.9 – 1.1 0.911 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.02 0.969 – 1.07 0.469 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 0.996 0.945 – 1.05 0.879 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 0.964 0.905 – 1.03 0.254 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.11 0.868 – 1.41 0.416 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.931 0.783 – 1.11 0.413 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.96 0.896 – 1.03 0.244 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.03 0.938 – 1.13 0.53 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.05 0.926 – 1.19 0.437 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.07 0.943 – 1.21 0.296 253 2529 all phecode
585 Renal failure Genitourinary 1 0.978 – 1.03 0.846 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 0.989 0.959 – 1.02 0.461 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 1.02 0.97 – 1.08 0.391 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.02 0.984 – 1.07 0.241 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 1.1 0.998 – 1.2 0.0544 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 1.01 0.975 – 1.05 0.57 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.08 0.943 – 1.25 0.257 208 2089 all phecode
586.11 Small kidney Genitourinary 1.06 0.914 – 1.24 0.426 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.03 0.974 – 1.09 0.295 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.25 1 – 1.56 0.0492 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.02 0.955 – 1.09 0.526 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 1.07 0.955 – 1.19 0.255 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 0.991 0.806 – 1.22 0.933 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 1.1 0.915 – 1.32 0.309 116 1158 all phecode
590 Pyelonephritis Genitourinary 1.03 0.971 – 1.09 0.348 1328 13285 all phecode
591 Urinary tract infection Genitourinary 0.988 0.97 – 1.01 0.214 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 1.02 0.981 – 1.06 0.342 2966 29661 all phecode
592.1 Cystitis Genitourinary 1.02 0.981 – 1.06 0.331 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 0.976 0.817 – 1.17 0.786 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 1.01 0.946 – 1.09 0.694 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.966 0.848 – 1.1 0.603 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.07 0.915 – 1.25 0.397 165 1662 all phecode
593 Hematuria Genitourinary 0.995 0.98 – 1.01 0.582 16068 160204 all phecode
594 Urinary calculus Genitourinary 1.01 0.988 – 1.04 0.292 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 1.03 0.996 – 1.07 0.0849 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 1.02 0.95 – 1.1 0.543 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 1.01 0.973 – 1.06 0.485 2401 24024 all phecode
594.8 Renal colic Genitourinary 0.994 0.95 – 1.04 0.785 2050 20500 all phecode
595 Hydronephrosis Genitourinary 0.975 0.931 – 1.02 0.293 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 0.995 0.975 – 1.02 0.656 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 0.963 0.92 – 1.01 0.114 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 0.984 0.935 – 1.03 0.519 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.02 0.983 – 1.05 0.334 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.02 0.984 – 1.06 0.272 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 0.962 0.767 – 1.21 0.74 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.03 0.995 – 1.07 0.0938 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 0.972 0.862 – 1.1 0.641 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.02 1 – 1.03 0.045 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 0.948 0.805 – 1.12 0.52 166 1670 all phecode
599.2 Retention of urine Genitourinary 1.02 0.99 – 1.04 0.235 6718 67168 all phecode
599.3 Dysuria Genitourinary 0.948 0.893 – 1.01 0.077 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 1.02 0.999 – 1.04 0.0626 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1.01 0.981 – 1.05 0.41 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 0.975 0.802 – 1.19 0.802 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 1.12 0.876 – 1.42 0.375 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 1.01 0.964 – 1.06 0.677 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 1.02 0.995 – 1.04 0.137 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.996 0.952 – 1.04 0.852 2081 20818 all phecode
601.1 Prostatitis Genitourinary 1 0.95 – 1.05 0.998 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 0.953 0.836 – 1.09 0.474 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 0.976 0.911 – 1.04 0.48 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.03 0.789 – 1.34 0.847 59 588 all phecode
601.4 Balanoposthitis Genitourinary 0.967 0.856 – 1.09 0.594 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.979 0.869 – 1.1 0.734 303 3019 all phecode
602 Other disorders of prostate Genitourinary 1 0.95 – 1.06 0.871 1341 13408 all phecode
603 Other disorders of testis Genitourinary 0.973 0.931 – 1.02 0.232 2150 21512 all phecode
603.1 Hydrocele Genitourinary 0.968 0.915 – 1.02 0.259 1339 13402 all phecode
604 Disorders of penis Genitourinary 1 0.964 – 1.04 0.988 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.987 0.949 – 1.03 0.521 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.01 0.889 – 1.14 0.93 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 0.993 0.955 – 1.03 0.718 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.973 0.844 – 1.12 0.707 214 2138 all phecode
609.1 Infertility, male Genitourinary 0.963 0.745 – 1.25 0.774 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 1.01 0.863 – 1.19 0.872 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 1.02 0.983 – 1.07 0.259 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 1.05 0.982 – 1.12 0.15 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.03 0.916 – 1.16 0.617 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 0.992 0.883 – 1.11 0.892 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 1.04 0.981 – 1.1 0.203 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.992 0.917 – 1.07 0.834 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.999 0.949 – 1.05 0.979 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 1.1 0.839 – 1.44 0.495 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 0.99 0.939 – 1.04 0.71 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.06 0.989 – 1.14 0.1 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.05 0.978 – 1.13 0.176 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 1.11 0.871 – 1.43 0.389 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 0.959 0.911 – 1.01 0.103 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 0.934 0.866 – 1.01 0.0793 720 7210 all phecode
613.5 Mastodynia Genitourinary 0.809 0.644 – 1.02 0.0708 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 1.02 0.943 – 1.1 0.619 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 1.07 0.958 – 1.2 0.222 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 0.863 0.749 – 0.995 0.042 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.967 0.941 – 0.994 0.0167 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.964 0.926 – 1 0.0794 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.951 0.886 – 1.02 0.168 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.01 0.774 – 1.32 0.948 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.948 0.858 – 1.05 0.297 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.986 0.884 – 1.1 0.796 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.933 0.825 – 1.05 0.267 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.966 0.928 – 1.01 0.0933 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 1 0.945 – 1.06 0.997 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.977 0.887 – 1.08 0.632 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.922 0.855 – 0.994 0.0342 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.982 0.867 – 1.11 0.773 274 2737 all phecode
615 Endometriosis Genitourinary 0.974 0.943 – 1.01 0.105 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.04 0.92 – 1.17 0.561 304 3037 all phecode
618 Genital prolapse Genitourinary 1.02 1 – 1.04 0.0142 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1.01 0.987 – 1.04 0.362 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.03 1.01 – 1.06 0.0188 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.08 0.986 – 1.18 0.099 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.04 0.963 – 1.13 0.305 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 0.989 0.968 – 1.01 0.337 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.947 0.878 – 1.02 0.154 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 0.97 0.936 – 1.01 0.0962 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.983 0.946 – 1.02 0.373 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.04 0.988 – 1.09 0.137 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.972 0.919 – 1.03 0.313 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 1.18 0.927 – 1.49 0.183 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 0.97 0.913 – 1.03 0.33 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 0.984 0.965 – 1 0.123 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.976 0.954 – 0.999 0.0394 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 0.979 0.945 – 1.01 0.23 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.03 0.969 – 1.09 0.377 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 0.96 0.893 – 1.03 0.269 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.931 0.817 – 1.06 0.289 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.969 0.879 – 1.07 0.524 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 1.03 1 – 1.06 0.0489 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.981 0.945 – 1.02 0.339 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 0.948 0.893 – 1.01 0.078 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.986 0.97 – 1 0.104 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.988 0.971 – 1.01 0.172 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.963 0.794 – 1.17 0.706 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 0.989 0.968 – 1.01 0.29 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 0.986 0.942 – 1.03 0.538 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 0.987 0.955 – 1.02 0.441 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 0.972 0.925 – 1.02 0.245 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 1.11 0.942 – 1.3 0.216 159 1587 all phecode
626.8 Infertility, female Genitourinary 0.965 0.914 – 1.02 0.209 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.971 0.952 – 0.991 0.00477 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 0.96 0.94 – 0.981 0.000217 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 0.994 0.853 – 1.16 0.934 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1 0.944 – 1.07 0.898 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 1.05 0.933 – 1.18 0.416 310 3097 all phecode
628 Ovarian cyst Genitourinary 0.968 0.94 – 0.997 0.0315 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.02 0.993 – 1.05 0.146 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.985 0.926 – 1.05 0.62 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.03 0.924 – 1.16 0.563 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.979 0.935 – 1.03 0.37 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.961 0.896 – 1.03 0.256 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.02 0.961 – 1.08 0.551 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.01 0.966 – 1.05 0.725 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 0.932 0.858 – 1.01 0.0944 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.05 0.985 – 1.12 0.139 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 0.944 0.746 – 1.19 0.63 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.02 0.955 – 1.08 0.625 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.04 0.928 – 1.17 0.495 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.928 0.809 – 1.06 0.28 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.05 0.89 – 1.23 0.58 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 0.999 0.943 – 1.06 0.973 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.998 0.956 – 1.04 0.919 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.06 0.826 – 1.36 0.644 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.12 0.993 – 1.27 0.0653 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.14 0.935 – 1.39 0.198 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.12 0.965 – 1.3 0.134 193 1922 all phecode
650 Normal delivery Pregnancy Complications 1 0.957 – 1.05 0.91 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 0.928 0.832 – 1.04 0.182 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.963 0.917 – 1.01 0.138 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.978 0.926 – 1.03 0.431 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.01 0.801 – 1.27 0.945 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.992 0.961 – 1.02 0.62 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.06 0.871 – 1.3 0.549 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.981 0.939 – 1.02 0.381 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.984 0.902 – 1.07 0.712 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 1 0.975 – 1.03 0.754 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1 0.96 – 1.04 0.987 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.998 0.849 – 1.17 0.979 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.967 0.854 – 1.09 0.595 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.935 0.72 – 1.21 0.611 63 624 all phecode
679 Complications of in utero procedures Dermatologic 1.11 0.849 – 1.46 0.44 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 0.998 0.974 – 1.02 0.871 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.9 0.825 – 0.981 0.0168 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.05 0.963 – 1.15 0.254 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1 0.975 – 1.03 0.833 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1 0.975 – 1.03 0.853 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1 0.973 – 1.03 0.979 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.02 0.938 – 1.11 0.624 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.04 0.979 – 1.1 0.217 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 1.01 0.966 – 1.05 0.688 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 1.01 0.931 – 1.1 0.753 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 1.03 0.925 – 1.15 0.595 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1 0.916 – 1.09 0.999 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.97 0.928 – 1.01 0.173 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.01 0.892 – 1.14 0.905 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 1.03 0.846 – 1.25 0.794 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 0.977 0.94 – 1.01 0.231 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 1 0.973 – 1.03 0.998 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.748 0.588 – 0.951 0.0176 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.804 0.605 – 1.07 0.13 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 0.852 0.707 – 1.03 0.0923 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.984 0.921 – 1.05 0.626 986 9854 all phecode
694.1 Vitiligo Dermatologic 0.849 0.657 – 1.1 0.208 60 599 all phecode
694.2 Other dyschromia Dermatologic 1 0.93 – 1.08 0.97 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 1.01 0.833 – 1.22 0.924 117 1170 all phecode
695 Erythematous conditions Dermatologic 0.968 0.928 – 1.01 0.123 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 1.06 0.869 – 1.29 0.566 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 0.899 0.756 – 1.07 0.23 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 0.937 0.719 – 1.22 0.628 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.941 0.744 – 1.19 0.614 73 727 all phecode
695.3 Rosacea Dermatologic 0.918 0.817 – 1.03 0.148 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 1.02 0.92 – 1.13 0.721 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.04 0.872 – 1.24 0.66 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 1.02 0.911 – 1.14 0.743 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 0.962 0.894 – 1.04 0.303 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 0.861 0.752 – 0.984 0.0283 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 0.831 0.658 – 1.05 0.122 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.02 0.928 – 1.12 0.694 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 0.977 0.936 – 1.02 0.303 2252 22509 all phecode
696.4 Psoriasis Dermatologic 0.976 0.934 – 1.02 0.275 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 0.981 0.933 – 1.03 0.46 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 0.994 0.92 – 1.07 0.871 706 7052 all phecode
697 Sarcoidosis Dermatologic 0.976 0.893 – 1.07 0.585 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 1.12 1.04 – 1.21 0.00187 782 7814 all phecode
700 Corns and callosities Dermatologic 0.968 0.858 – 1.09 0.591 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.01 0.982 – 1.04 0.442 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 0.912 0.738 – 1.13 0.397 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.01 0.965 – 1.05 0.764 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.23 0.944 – 1.6 0.126 61 610 all phecode
701.4 Keloid scar Dermatologic 1.05 0.912 – 1.21 0.501 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.02 0.925 – 1.12 0.701 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 0.923 0.756 – 1.13 0.432 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.996 0.969 – 1.02 0.782 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 0.978 0.94 – 1.02 0.288 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 1.01 0.973 – 1.05 0.599 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 0.963 0.865 – 1.07 0.484 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 1.04 0.975 – 1.11 0.236 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 1 0.977 – 1.03 0.75 5267 52727 all phecode
704.1 Alopecia Dermatologic 1.12 0.927 – 1.34 0.247 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.1 0.863 – 1.4 0.44 76 759 all phecode
705 Disorders of sweat glands Dermatologic 1.03 0.899 – 1.17 0.69 228 2287 all phecode
705.3 Hidradenitis Dermatologic 1.04 0.897 – 1.21 0.587 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 1.07 0.979 – 1.16 0.142 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 0.996 0.974 – 1.02 0.724 8317 83195 all phecode
706.1 Acne Dermatologic 1.14 0.917 – 1.43 0.233 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 0.994 0.972 – 1.02 0.573 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 1 0.955 – 1.05 0.986 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 0.998 0.933 – 1.07 0.947 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.99 0.956 – 1.03 0.587 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 1.01 0.924 – 1.11 0.814 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 0.92 0.791 – 1.07 0.285 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.726 0.564 – 0.934 0.0128 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.991 0.953 – 1.03 0.657 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.979 0.901 – 1.06 0.614 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 0.981 0.9 – 1.07 0.657 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.966 0.834 – 1.12 0.64 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.989 0.894 – 1.09 0.822 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.04 0.94 – 1.14 0.471 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.05 0.942 – 1.18 0.365 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.22 0.977 – 1.53 0.0784 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.01 0.855 – 1.2 0.875 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 0.87 0.67 – 1.13 0.298 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.986 0.957 – 1.02 0.346 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.978 0.948 – 1.01 0.158 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.01 0.96 – 1.06 0.712 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 0.986 0.816 – 1.19 0.882 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.958 0.883 – 1.04 0.31 618 6177 all phecode
716 Other arthropathies Musculoskeletal 0.99 0.979 – 1 0.0751 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1 0.97 – 1.04 0.794 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.972 0.956 – 0.988 0.000826 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 0.989 0.978 – 1 0.0577 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 0.979 0.921 – 1.04 0.492 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 1.01 0.977 – 1.05 0.538 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 0.986 0.963 – 1.01 0.223 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.982 0.954 – 1.01 0.231 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.944 0.813 – 1.1 0.446 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 0.992 0.89 – 1.11 0.884 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 1.01 0.988 – 1.03 0.382 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.941 0.859 – 1.03 0.19 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.01 0.969 – 1.05 0.701 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.02 0.804 – 1.3 0.849 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.01 0.978 – 1.04 0.565 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 0.959 0.876 – 1.05 0.36 517 5173 all phecode
723.1 Torticollis Musculoskeletal 0.86 0.707 – 1.05 0.13 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.01 0.969 – 1.06 0.564 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 1 0.904 – 1.11 0.969 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 0.995 0.899 – 1.1 0.93 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 0.959 0.738 – 1.25 0.752 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.01 0.965 – 1.07 0.572 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1 0.985 – 1.02 0.864 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 1 0.98 – 1.02 0.943 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 1.05 0.936 – 1.17 0.431 334 3336 all phecode
726.3 Bursitis Musculoskeletal 1.01 0.941 – 1.08 0.804 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.01 0.984 – 1.03 0.524 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.987 0.949 – 1.03 0.497 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 1.07 0.873 – 1.31 0.518 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.02 0.984 – 1.06 0.276 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 1.05 0.967 – 1.15 0.234 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.981 0.88 – 1.09 0.737 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.01 0.852 – 1.2 0.892 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.962 0.93 – 0.995 0.0235 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.99 0.894 – 1.1 0.839 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 0.965 0.934 – 0.998 0.0362 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.965 0.932 – 0.999 0.0438 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 0.986 0.96 – 1.01 0.308 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 0.98 0.918 – 1.05 0.541 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 0.986 0.803 – 1.21 0.896 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.943 0.833 – 1.07 0.356 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.95 0.837 – 1.08 0.425 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 1.07 0.969 – 1.17 0.191 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.19 1.04 – 1.38 0.015 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.969 0.739 – 1.27 0.819 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.03 0.986 – 1.09 0.167 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 0.987 0.878 – 1.11 0.824 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.982 0.899 – 1.07 0.682 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 1.1 0.916 – 1.31 0.316 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 0.998 0.941 – 1.06 0.937 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 1.06 0.877 – 1.28 0.555 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 1.01 0.988 – 1.03 0.394 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 0.917 0.792 – 1.06 0.25 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 1.02 0.993 – 1.05 0.142 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.04 0.991 – 1.09 0.111 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 0.982 0.933 – 1.03 0.504 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1.01 0.987 – 1.04 0.348 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 0.985 0.937 – 1.04 0.572 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 0.984 0.866 – 1.12 0.802 248 2476 all phecode
737 Curvature of spine Musculoskeletal 1 0.944 – 1.07 0.901 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.01 0.944 – 1.07 0.859 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.01 0.961 – 1.06 0.769 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.992 0.941 – 1.05 0.772 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 0.949 0.865 – 1.04 0.265 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 0.993 0.981 – 1.01 0.28 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 0.989 0.974 – 1 0.157 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.996 0.975 – 1.02 0.749 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.01 0.899 – 1.12 0.926 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.01 0.925 – 1.09 0.894 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 0.994 0.976 – 1.01 0.523 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.01 0.978 – 1.05 0.479 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 0.952 0.778 – 1.17 0.636 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 1.03 0.944 – 1.11 0.556 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 1.1 0.936 – 1.3 0.244 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 1 0.952 – 1.06 0.862 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 0.962 0.793 – 1.17 0.695 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 0.865 0.647 – 1.16 0.331 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.999 0.961 – 1.04 0.946 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 1.02 0.909 – 1.14 0.777 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.02 0.827 – 1.26 0.847 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.04 0.945 – 1.14 0.447 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 0.987 0.942 – 1.03 0.573 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.01 0.986 – 1.03 0.423 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 1.01 0.981 – 1.03 0.624 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 1.01 0.98 – 1.04 0.598 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 0.994 0.91 – 1.09 0.898 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 1 0.917 – 1.1 0.937 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.02 0.951 – 1.1 0.545 815 8144 all phecode
745 Pain in joint Musculoskeletal 0.98 0.958 – 1 0.0828 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.978 0.941 – 1.02 0.269 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.979 0.94 – 1.02 0.295 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.966 0.887 – 1.05 0.426 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.94 0.824 – 1.07 0.355 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.997 0.95 – 1.05 0.898 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.967 0.827 – 1.13 0.677 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.16 0.873 – 1.55 0.302 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.999 0.89 – 1.12 0.993 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 0.97 0.897 – 1.05 0.449 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 0.996 0.889 – 1.12 0.943 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.917 0.791 – 1.06 0.252 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.945 0.847 – 1.05 0.306 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.879 0.767 – 1.01 0.0631 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1 0.827 – 1.21 0.994 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.979 0.929 – 1.03 0.417 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.988 0.915 – 1.07 0.766 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.95 0.864 – 1.05 0.294 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.09 0.955 – 1.25 0.195 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.974 0.908 – 1.05 0.472 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 0.999 0.904 – 1.1 0.981 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.07 0.956 – 1.2 0.241 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.919 0.821 – 1.03 0.146 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 0.946 0.833 – 1.07 0.39 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 0.975 0.847 – 1.12 0.726 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.904 0.711 – 1.15 0.41 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 0.936 0.782 – 1.12 0.472 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.03 0.819 – 1.3 0.783 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.05 0.87 – 1.27 0.598 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1.01 0.911 – 1.11 0.91 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.94 0.815 – 1.08 0.396 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.963 0.822 – 1.13 0.642 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.1 0.911 – 1.34 0.315 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.05 0.964 – 1.14 0.267 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.973 0.779 – 1.22 0.809 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.08 0.981 – 1.19 0.114 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.938 0.798 – 1.1 0.44 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.938 0.729 – 1.21 0.615 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.929 0.81 – 1.07 0.292 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.01 0.826 – 1.23 0.925 96 959 all phecode
760 Back pain Symptoms 1 0.982 – 1.02 0.878 11126 111353 all phecode
761 Cervicalgia Symptoms 0.994 0.947 – 1.04 0.8 1791 17901 all phecode
764 Sciatica Symptoms 0.99 0.949 – 1.03 0.647 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.97 0.914 – 1.03 0.312 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 1.06 0.974 – 1.15 0.185 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.998 0.931 – 1.07 0.959 870 8687 all phecode
771.1 Swelling of limb Symptoms 0.987 0.957 – 1.02 0.383 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 0.96 0.886 – 1.04 0.314 659 6581 all phecode
773 Pain in limb Symptoms 0.997 0.971 – 1.02 0.828 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 0.913 0.779 – 1.07 0.263 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.03 0.985 – 1.08 0.176 1870 18715 all phecode
782.3 Edema Symptoms 0.995 0.946 – 1.05 0.848 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 1.04 0.889 – 1.21 0.637 175 1748 all phecode
783 Fever of unknown origin Symptoms 0.988 0.956 – 1.02 0.469 3911 39105 all phecode
785 Abdominal pain Symptoms 0.997 0.987 – 1.01 0.633 40080 301686 all phecode
788 Syncope and collapse Symptoms 0.977 0.956 – 0.998 0.0344 9069 90813 all phecode
789 Nausea and vomiting Symptoms 0.993 0.974 – 1.01 0.475 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.04 0.884 – 1.23 0.622 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 0.758 0.609 – 0.945 0.0138 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 0.991 0.966 – 1.02 0.494 6357 63635 all phecode
791 Gangrene Symptoms 1.1 1.01 – 1.2 0.0339 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.968 0.79 – 1.19 0.752 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.07 0.892 – 1.28 0.481 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1 0.923 – 1.09 0.911 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.849 0.704 – 1.02 0.0866 120 1198 all phecode
797 Shock Symptoms 1.07 0.903 – 1.27 0.441 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 1.07 0.871 – 1.32 0.507 102 1020 all phecode
798 Malaise and fatigue Symptoms 0.989 0.955 – 1.02 0.555 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 0.992 0.912 – 1.08 0.856 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 0.996 0.972 – 1.02 0.732 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.972 0.926 – 1.02 0.247 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.04 0.89 – 1.22 0.603 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.03 0.984 – 1.08 0.209 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 0.981 0.91 – 1.06 0.625 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.986 0.944 – 1.03 0.537 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.01 0.959 – 1.06 0.804 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 0.991 0.918 – 1.07 0.82 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 1.03 1 – 1.05 0.0286 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.01 0.961 – 1.06 0.688 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.03 0.996 – 1.05 0.0881 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.02 0.967 – 1.07 0.477 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.976 0.942 – 1.01 0.182 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.993 0.939 – 1.05 0.81 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 1.01 0.943 – 1.09 0.695 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 1 0.945 – 1.06 0.981 1300 12998 all phecode
817 Concussion Injuries & Poisonings 1.03 0.897 – 1.17 0.715 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 0.996 0.909 – 1.09 0.925 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.02 0.979 – 1.06 0.379 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 1.02 0.969 – 1.07 0.465 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 1.02 0.973 – 1.07 0.438 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 0.99 0.973 – 1.01 0.227 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.1 1.01 – 1.2 0.0372 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 0.998 0.909 – 1.1 0.967 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.03 0.998 – 1.06 0.0651 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.1 0.932 – 1.3 0.257 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.01 0.917 – 1.1 0.895 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 0.988 0.941 – 1.04 0.613 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.993 0.937 – 1.05 0.815 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.03 0.992 – 1.07 0.13 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.01 0.97 – 1.04 0.773 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1.02 0.794 – 1.32 0.861 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.979 0.946 – 1.01 0.238 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.931 0.818 – 1.06 0.281 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.918 0.793 – 1.06 0.248 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.972 0.935 – 1.01 0.14 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.02 0.887 – 1.17 0.808 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 1.03 0.799 – 1.32 0.83 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 1 0.968 – 1.03 0.98 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 1.02 0.77 – 1.36 0.878 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.01 0.82 – 1.25 0.911 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.92 0.791 – 1.07 0.283 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 1.01 0.916 – 1.11 0.888 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 0.993 0.868 – 1.14 0.916 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.03 0.883 – 1.2 0.71 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.08 0.918 – 1.28 0.349 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.02 0.961 – 1.08 0.561 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 0.999 0.968 – 1.03 0.942 4260 42663 all phecode
916 Contusion Injuries & Poisonings 1.02 0.965 – 1.08 0.494 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 1.01 0.866 – 1.18 0.87 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.937 0.844 – 1.04 0.215 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.934 0.821 – 1.06 0.305 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.975 0.932 – 1.02 0.279 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.07 0.933 – 1.22 0.349 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 1.01 0.823 – 1.24 0.926 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.982 0.899 – 1.07 0.695 550 5509 all phecode
947 Urticaria Injuries & Poisonings 1.02 0.916 – 1.14 0.703 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 0.938 0.845 – 1.04 0.228 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.964 0.873 – 1.06 0.471 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.01 0.891 – 1.14 0.89 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.912 0.83 – 1 0.055 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 0.862 0.654 – 1.14 0.295 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.881 0.691 – 1.12 0.305 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 0.995 0.98 – 1.01 0.541 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 0.993 0.977 – 1.01 0.421 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.02 0.92 – 1.13 0.74 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.99 0.923 – 1.06 0.775 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 0.988 0.886 – 1.1 0.822 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 0.979 0.876 – 1.09 0.701 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.972 0.847 – 1.12 0.687 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1 0.89 – 1.13 0.964 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.01 0.895 – 1.14 0.889 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 0.982 0.956 – 1.01 0.174 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.944 0.888 – 1 0.0631 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.927 0.844 – 1.02 0.114 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.874 0.789 – 0.967 0.00901 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.986 0.899 – 1.08 0.755 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 0.992 0.912 – 1.08 0.845 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 0.989 0.944 – 1.04 0.634 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.893 0.772 – 1.03 0.128 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.935 0.827 – 1.06 0.29 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.951 0.765 – 1.18 0.65 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 0.969 0.795 – 1.18 0.757 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.01 0.83 – 1.23 0.907 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.778 0.606 – 0.999 0.0491 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 0.933 0.716 – 1.22 0.607 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1.01 0.881 – 1.15 0.937 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.05 0.969 – 1.13 0.247 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.04 0.901 – 1.19 0.623 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 0.713 0.558 – 0.912 0.00701 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 0.91 0.746 – 1.11 0.356 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.894 0.735 – 1.09 0.26 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.834 0.68 – 1.02 0.0798 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 0.989 0.953 – 1.03 0.553 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 0.993 0.957 – 1.03 0.729 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 0.993 0.957 – 1.03 0.729 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 0.998 0.971 – 1.03 0.883 5538 63928 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.02 0.973 – 1.08 0.373 1663 19453 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.01 0.902 – 1.13 0.876 316 4512 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1 0.915 – 1.09 0.99 514 6251 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 0.797 0.573 – 1.11 0.178 32 412 exclusion phecode
010 Tuberculosis Infectious Diseases 0.906 0.742 – 1.11 0.335 100 1154 exclusion phecode
038 Septicemia Infectious Diseases 0.997 0.954 – 1.04 0.906 2126 29197 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.02 0.923 – 1.12 0.714 415 5900 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.03 0.904 – 1.18 0.642 227 3457 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.04 1.02 – 1.07 0.000556 6955 85937 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.14 1.08 – 1.19 5.39e-07 1679 22196 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.05 0.988 – 1.13 0.108 976 11987 exclusion phecode
041.4 E. coli Infectious Diseases 1.03 0.976 – 1.08 0.286 1520 19569 exclusion phecode
053 Herpes zoster Infectious Diseases 1.09 0.945 – 1.25 0.246 225 2821 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 1.03 0.786 – 1.35 0.836 57 644 exclusion phecode
054 Herpes simplex Infectious Diseases 0.895 0.757 – 1.06 0.192 141 1606 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.03 0.924 – 1.16 0.568 323 4477 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 0.85 0.635 – 1.14 0.273 48 549 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 1.05 0.834 – 1.31 0.694 73 968 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.09 0.912 – 1.3 0.348 132 2012 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 0.975 0.826 – 1.15 0.767 140 2057 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.05 0.914 – 1.2 0.511 224 3107 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 0.875 0.693 – 1.11 0.265 73 1099 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 0.816 0.632 – 1.06 0.121 59 878 exclusion phecode
078 Viral warts & HPV Infectious Diseases 1.01 0.934 – 1.09 0.819 706 7578 exclusion phecode
079 Viral infection Infectious Diseases 0.965 0.92 – 1.01 0.133 1923 21181 exclusion phecode
079.1 Varicella infection Infectious Diseases 0.826 0.608 – 1.12 0.221 46 518 exclusion phecode
080 Postoperative infection Infectious Diseases 1.03 0.986 – 1.07 0.204 2675 32311 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.04 0.985 – 1.1 0.151 1363 17494 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.993 0.742 – 1.33 0.961 45 535 exclusion phecode
1000 Burns Injuries & Poisonings 1.09 0.984 – 1.21 0.0979 381 4263 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 1.04 0.965 – 1.11 0.328 822 8739 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.02 0.985 – 1.06 0.272 3520 39155 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.06 0.912 – 1.23 0.463 191 2193 exclusion phecode
1005 Other symptoms Injuries & Poisonings 0.971 0.907 – 1.04 0.406 863 10313 exclusion phecode
1006 Crushing injury Injuries & Poisonings 0.924 0.794 – 1.07 0.303 176 1821 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 0.982 0.84 – 1.15 0.819 178 1913 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.02 0.947 – 1.1 0.563 707 7313 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 1.01 0.987 – 1.04 0.31 5883 62296 exclusion phecode
1010 Other tests Injuries & Poisonings 1.01 0.974 – 1.04 0.682 3788 42750 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.01 0.986 – 1.04 0.333 5585 64404 exclusion phecode
1012 Late effect Injuries & Poisonings 0.857 0.678 – 1.08 0.194 76 764 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 0.976 0.847 – 1.12 0.739 199 2244 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 0.959 0.731 – 1.26 0.763 53 489 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 0.975 0.938 – 1.01 0.213 2671 31277 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.01 0.991 – 1.03 0.273 10738 116961 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.947 0.81 – 1.11 0.499 161 1992 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 0.968 0.825 – 1.14 0.689 157 1957 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.806 0.607 – 1.07 0.137 47 532 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.01 0.806 – 1.27 0.923 77 994 exclusion phecode
112 Candidiasis Infectious Diseases 1.02 0.965 – 1.08 0.463 1280 15203 exclusion phecode
117 Mycoses Infectious Diseases 1.12 0.94 – 1.32 0.209 142 1917 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.13 0.914 – 1.41 0.252 85 1129 exclusion phecode
130 Spirochetal infection Infectious Diseases 0.835 0.638 – 1.09 0.188 54 603 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 0.844 0.629 – 1.13 0.259 44 522 exclusion phecode
134 Helminthiases Infectious Diseases 0.872 0.696 – 1.09 0.233 85 996 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 0.915 0.714 – 1.17 0.482 70 838 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 0.956 0.798 – 1.14 0.623 124 1464 exclusion phecode
145 Cancer of mouth Neoplasms 0.963 0.873 – 1.06 0.451 440 4516 exclusion phecode
145.2 Cancer of tongue Neoplasms 0.99 0.862 – 1.14 0.887 217 2145 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 0.94 0.734 – 1.2 0.625 68 791 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 1 0.723 – 1.39 0.985 37 369 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 1 0.902 – 1.11 0.983 392 4321 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 1.1 0.942 – 1.29 0.227 170 1800 exclusion phecode
149.4 Cancer of larynx Neoplasms 0.952 0.804 – 1.13 0.568 140 1718 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 0.947 0.692 – 1.3 0.733 40 382 exclusion phecode
150 Cancer of esophagus Neoplasms 0.929 0.845 – 1.02 0.135 441 4965 exclusion phecode
151 Cancer of stomach Neoplasms 0.906 0.812 – 1.01 0.0786 331 3675 exclusion phecode
153 Colorectal cancer Neoplasms 0.971 0.936 – 1.01 0.131 2982 31087 exclusion phecode
153.2 Colon cancer Neoplasms 0.968 0.925 – 1.01 0.169 2015 20964 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.983 0.931 – 1.04 0.531 1419 14778 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.974 0.851 – 1.11 0.697 220 2702 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.967 0.763 – 1.23 0.78 69 1024 exclusion phecode
157 Pancreatic cancer Neoplasms 0.946 0.854 – 1.05 0.285 398 4402 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 0.996 0.921 – 1.08 0.915 686 7382 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.971 0.938 – 1 0.0906 3553 37731 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.98 0.816 – 1.18 0.83 130 1326 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.931 0.777 – 1.12 0.442 131 1394 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.14 0.941 – 1.37 0.183 122 1346 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 0.879 0.638 – 1.21 0.432 41 409 exclusion phecode
165 Cancer within the respiratory system Neoplasms 0.989 0.94 – 1.04 0.657 1593 18688 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.02 0.961 – 1.08 0.535 1233 14797 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 1.04 0.924 – 1.18 0.5 295 3027 exclusion phecode
170.1 Bone cancer Neoplasms 1.26 1.01 – 1.57 0.0396 84 899 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1.03 0.9 – 1.19 0.64 225 2294 exclusion phecode
172 Skin cancer Neoplasms 0.989 0.968 – 1.01 0.322 9327 92779 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.927 0.884 – 0.971 0.00147 1928 19087 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.924 0.882 – 0.968 0.000895 1951 19315 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 1 0.977 – 1.02 0.965 7542 74823 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 1.01 0.912 – 1.12 0.866 406 4415 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 1.01 0.844 – 1.21 0.9 128 1321 exclusion phecode
174 Breast cancer Neoplasms 1 0.983 – 1.02 0.745 9487 97258 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1 0.982 – 1.02 0.791 9353 95789 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1 0.979 – 1.02 0.927 8789 90219 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.09 0.885 – 1.35 0.41 93 905 exclusion phecode
175 Acquired absence of breast Neoplasms 1.02 0.968 – 1.07 0.498 1768 18613 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 1.04 0.989 – 1.09 0.128 1779 18031 exclusion phecode
180.1 Cervical cancer Neoplasms 0.947 0.825 – 1.09 0.44 214 2176 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 1.04 0.992 – 1.1 0.096 1703 17213 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.912 0.85 – 0.977 0.00915 847 9520 exclusion phecode
184 Cancer of other female genital organs Neoplasms 1.03 0.963 – 1.1 0.413 1010 10505 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.04 0.96 – 1.12 0.356 715 7284 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.03 0.953 – 1.11 0.452 693 7046 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.96 0.838 – 1.1 0.562 219 2371 exclusion phecode
185 Cancer of prostate Neoplasms 1.01 0.972 – 1.04 0.757 3690 35865 exclusion phecode
187 Cancer of other male genital organs Neoplasms 0.909 0.809 – 1.02 0.108 304 3153 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.12 0.819 – 1.53 0.478 40 438 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 0.849 0.735 – 0.979 0.0247 199 2112 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.882 0.7 – 1.11 0.284 75 735 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.02 0.976 – 1.07 0.375 2136 27012 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.981 0.89 – 1.08 0.695 403 7221 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.986 0.892 – 1.09 0.774 383 6951 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 0.862 0.609 – 1.22 0.4 31 434 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.02 0.968 – 1.08 0.424 1356 15398 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 1.01 0.955 – 1.07 0.668 1195 13676 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.747 0.576 – 0.971 0.029 58 938 exclusion phecode
190 Cancer of eye Neoplasms 0.95 0.792 – 1.14 0.58 122 1233 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.919 0.837 – 1.01 0.0764 471 4848 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.947 0.854 – 1.05 0.298 389 3944 exclusion phecode
191.11 Cancer of brain Neoplasms 0.944 0.848 – 1.05 0.293 362 3669 exclusion phecode
193 Thyroid cancer Neoplasms 0.901 0.789 – 1.03 0.125 234 2652 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 0.814 0.627 – 1.06 0.123 58 701 exclusion phecode
195 Cancer, suspected or other Neoplasms 0.997 0.977 – 1.02 0.726 11114 116438 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 0.995 0.976 – 1.02 0.653 10621 111911 exclusion phecode
197 Chemotherapy Neoplasms 1.01 0.996 – 1.03 0.136 14014 156042 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 0.996 0.971 – 1.02 0.765 6170 67750 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.01 0.972 – 1.04 0.734 3642 38998 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.957 0.906 – 1.01 0.11 1380 15988 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.01 0.946 – 1.08 0.779 1009 11039 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 0.983 0.935 – 1.03 0.501 1657 18449 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.942 0.863 – 1.03 0.186 527 6027 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.04 0.978 – 1.1 0.233 1291 14889 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.728 0.603 – 0.88 0.00105 119 1353 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 0.993 0.926 – 1.07 0.852 841 10306 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.06 0.768 – 1.46 0.729 39 706 exclusion phecode
200 Myeloproliferative disease Neoplasms 0.972 0.886 – 1.07 0.544 480 6747 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.02 0.871 – 1.19 0.81 162 2584 exclusion phecode
201 Hodgkin's disease Neoplasms 0.937 0.803 – 1.09 0.407 160 1976 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.03 0.974 – 1.09 0.301 1288 15846 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.05 0.988 – 1.12 0.111 1012 12512 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.12 0.977 – 1.29 0.102 220 2507 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.02 0.912 – 1.14 0.713 328 4022 exclusion phecode
204 Leukemia Neoplasms 1.01 0.944 – 1.08 0.786 926 11320 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 0.964 0.86 – 1.08 0.536 317 3872 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 0.859 0.613 – 1.2 0.377 34 413 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.976 0.862 – 1.1 0.695 270 3393 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.04 0.916 – 1.17 0.567 271 3228 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 1.08 0.93 – 1.25 0.313 182 2296 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.01 0.823 – 1.23 0.951 103 1010 exclusion phecode
204.4 Multiple myeloma Neoplasms 0.929 0.824 – 1.05 0.232 287 3744 exclusion phecode
208 Benign neoplasm of colon Neoplasms 0.982 0.964 – 1 0.0484 12795 134394 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1.04 0.964 – 1.13 0.295 681 7213 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 0.994 0.96 – 1.03 0.717 3571 37441 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.917 0.802 – 1.05 0.207 234 2505 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.01 0.884 – 1.15 0.878 244 2393 exclusion phecode
214 Lipoma Neoplasms 0.989 0.958 – 1.02 0.47 4392 45251 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 0.994 0.959 – 1.03 0.735 3277 33835 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.08 1 – 1.15 0.045 820 8233 exclusion phecode
216 Benign neoplasm of skin Neoplasms 1.01 0.985 – 1.04 0.387 5724 57581 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 0.995 0.901 – 1.1 0.929 435 4529 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 1.02 0.917 – 1.13 0.758 409 4246 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 1 0.979 – 1.02 0.879 8074 81251 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 1 0.98 – 1.03 0.815 8240 82633 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 1.03 0.907 – 1.16 0.675 269 2832 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.976 0.919 – 1.04 0.442 1120 11458 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 1.02 0.872 – 1.19 0.823 173 1750 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 1.1 0.888 – 1.35 0.395 94 1038 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.09 0.882 – 1.34 0.436 100 1152 exclusion phecode
224 Benign neoplasm of eye Neoplasms 1.07 0.859 – 1.34 0.532 78 954 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.1 0.801 – 1.51 0.551 37 458 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.983 0.902 – 1.07 0.691 563 5999 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.986 0.902 – 1.08 0.754 528 5694 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.914 0.668 – 1.25 0.575 43 455 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.981 0.851 – 1.13 0.787 196 2039 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 0.999 0.916 – 1.09 0.983 548 6287 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 0.923 0.762 – 1.12 0.413 106 1354 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.13 0.99 – 1.29 0.0693 237 2662 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.926 0.801 – 1.07 0.298 204 2262 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 1.04 0.973 – 1.1 0.274 1141 11659 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.01 0.958 – 1.05 0.828 1842 18187 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.08 0.973 – 1.19 0.154 414 4535 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.994 0.924 – 1.07 0.872 779 8411 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.04 0.93 – 1.15 0.523 357 3598 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.962 0.873 – 1.06 0.425 451 5090 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 0.971 0.916 – 1.03 0.335 1162 13999 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 0.862 0.773 – 0.961 0.00742 327 3632 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 1.12 0.863 – 1.44 0.403 57 715 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.953 0.778 – 1.17 0.641 95 1059 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.01 0.988 – 1.03 0.416 9219 108660 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.01 0.932 – 1.09 0.867 700 8273 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.994 0.764 – 1.29 0.962 60 769 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.01 0.987 – 1.03 0.437 8765 103937 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.904 0.785 – 1.04 0.158 201 2279 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.919 0.781 – 1.08 0.304 153 1716 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.933 0.789 – 1.1 0.413 145 1639 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 0.908 0.802 – 1.03 0.133 260 3014 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.02 1 – 1.04 0.0334 10925 131077 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.986 0.935 – 1.04 0.606 1489 19737 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.889 0.75 – 1.05 0.177 140 1800 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.39 0.766 – 2.52 0.28 8 556 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.981 0.854 – 1.13 0.791 222 3357 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 0.992 0.755 – 1.3 0.953 51 1141 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.02 1 – 1.05 0.0222 9579 118577 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 0.869 0.672 – 1.12 0.284 61 768 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.19 0.825 – 1.72 0.351 25 1338 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 0.99 0.894 – 1.1 0.854 397 6711 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.09 0.931 – 1.27 0.295 164 3447 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 0.949 0.858 – 1.05 0.305 400 4888 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.94 0.806 – 1.1 0.436 172 1858 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.969 0.847 – 1.11 0.643 228 3014 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.894 0.736 – 1.09 0.257 104 1107 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.02 0.856 – 1.23 0.793 124 2404 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1 0.92 – 1.09 0.982 596 9087 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 1.05 0.956 – 1.15 0.308 451 6676 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 0.975 0.888 – 1.07 0.603 461 6281 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 0.974 0.882 – 1.08 0.601 417 5639 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 0.868 0.671 – 1.12 0.278 59 1003 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 0.948 0.858 – 1.05 0.294 413 4880 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.01 0.845 – 1.22 0.882 122 1392 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 0.99 0.772 – 1.27 0.937 61 699 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.944 0.797 – 1.12 0.5 143 1869 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.907 0.681 – 1.21 0.503 47 715 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 0.939 0.775 – 1.14 0.524 107 1033 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.988 0.887 – 1.1 0.834 337 4714 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.13 0.915 – 1.39 0.257 90 1352 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.08 0.825 – 1.41 0.581 52 805 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.18 0.868 – 1.6 0.291 38 549 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 0.9 0.776 – 1.04 0.162 185 2651 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 0.901 0.777 – 1.04 0.167 185 2645 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 1.02 0.885 – 1.18 0.756 204 2141 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.03 0.879 – 1.2 0.736 174 1876 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 0.841 0.682 – 1.04 0.107 87 1131 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 0.864 0.695 – 1.07 0.189 80 1064 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.987 0.757 – 1.29 0.923 55 752 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 1.04 0.854 – 1.26 0.723 102 1134 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.941 0.784 – 1.13 0.517 117 1414 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.16 0.801 – 1.67 0.437 27 340 exclusion phecode
260.6 Anorexia Endocrine/metabolic 0.974 0.889 – 1.07 0.562 494 5856 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 0.95 0.879 – 1.03 0.193 692 8706 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 0.933 0.848 – 1.03 0.159 440 5454 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.03 0.908 – 1.17 0.643 258 3312 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.863 0.624 – 1.19 0.374 36 575 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.05 0.895 – 1.24 0.523 152 1775 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.14 0.967 – 1.33 0.12 158 2372 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.02 0.872 – 1.2 0.777 160 2051 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.04 0.872 – 1.24 0.677 134 1749 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.03 0.838 – 1.27 0.763 94 1263 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 0.933 0.716 – 1.22 0.61 55 764 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.19 0.861 – 1.64 0.292 36 475 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 0.872 0.712 – 1.07 0.185 109 1184 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 0.831 0.671 – 1.03 0.0907 99 1039 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1 0.985 – 1.01 0.965 20417 170572 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.999 0.985 – 1.01 0.927 20374 170389 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.999 0.984 – 1.01 0.904 18889 164486 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.816 0.595 – 1.12 0.207 38 411 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 0.974 0.789 – 1.2 0.81 84 1154 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.03 0.856 – 1.23 0.769 118 1442 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 0.981 0.933 – 1.03 0.459 1596 24798 exclusion phecode
274.1 Gout Endocrine/metabolic 0.966 0.912 – 1.02 0.236 1237 20817 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 0.954 0.722 – 1.26 0.739 51 735 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.04 0.934 – 1.15 0.494 384 4360 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.08 0.966 – 1.2 0.179 356 3988 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.06 0.997 – 1.12 0.0619 1172 14742 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 0.994 0.901 – 1.1 0.909 423 4588 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.14 0.99 – 1.32 0.0689 200 2573 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.08 1 – 1.18 0.0509 610 8470 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.11 0.909 – 1.35 0.308 100 1209 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.01 0.98 – 1.05 0.421 3665 50343 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.05 1 – 1.09 0.0511 2110 28095 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.13 0.942 – 1.36 0.184 121 1585 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 0.999 0.939 – 1.06 0.984 1071 12445 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.04 0.93 – 1.17 0.486 311 6533 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.11 1.03 – 1.19 0.00767 773 10104 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1.01 0.916 – 1.11 0.899 470 7952 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.03 0.93 – 1.13 0.603 420 7243 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 0.955 0.719 – 1.27 0.751 52 746 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 0.965 0.914 – 1.02 0.191 1409 19646 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.05 0.889 – 1.24 0.558 151 3022 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 1.04 0.838 – 1.29 0.729 88 971 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.02 0.931 – 1.11 0.695 517 6497 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.909 0.796 – 1.04 0.156 238 2573 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.04 0.877 – 1.25 0.623 132 1611 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.21 0.818 – 1.8 0.335 26 367 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.03 1.01 – 1.06 0.0175 5600 79880 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.03 1.01 – 1.06 0.0143 5501 78655 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 1.12 0.874 – 1.45 0.363 61 686 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 0.723 0.514 – 1.02 0.0622 32 510 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 0.994 0.841 – 1.17 0.941 144 1853 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 0.987 0.823 – 1.19 0.892 121 1545 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 0.95 0.76 – 1.19 0.65 77 1012 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 1.1 0.936 – 1.3 0.24 164 1594 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.01 0.984 – 1.04 0.368 4717 56023 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.01 0.982 – 1.04 0.413 4497 53665 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.02 0.907 – 1.14 0.792 322 3555 exclusion phecode
281 Other deficiency anemia Hematopoietic 0.989 0.912 – 1.07 0.787 613 8034 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 0.985 0.907 – 1.07 0.718 593 7703 exclusion phecode
281.11 Pernicious anemia Hematopoietic 0.929 0.843 – 1.02 0.14 430 5434 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 0.902 0.743 – 1.09 0.296 103 1327 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 1.31 1.04 – 1.63 0.019 80 1277 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.04 0.709 – 1.52 0.843 23 369 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 0.872 0.698 – 1.09 0.228 77 1087 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 0.798 0.57 – 1.12 0.19 33 406 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.01 0.74 – 1.38 0.941 42 618 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 0.838 0.654 – 1.07 0.164 59 972 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.823 0.625 – 1.08 0.165 45 730 exclusion phecode
284 Aplastic anemia Hematopoietic 1.04 0.902 – 1.2 0.585 200 3051 exclusion phecode
285 Other anemias Hematopoietic 1.01 0.99 – 1.04 0.235 7059 87513 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 1 0.865 – 1.16 0.991 185 2064 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 0.989 0.877 – 1.12 0.861 268 4887 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 0.987 0.867 – 1.12 0.848 235 2923 exclusion phecode
286 Coagulation defects Hematopoietic 0.987 0.906 – 1.07 0.757 557 6766 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 1.02 0.908 – 1.14 0.753 317 3459 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.983 0.774 – 1.25 0.891 74 734 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 1.06 0.914 – 1.22 0.457 201 2233 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.08 0.76 – 1.52 0.68 38 460 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.22 0.877 – 1.69 0.241 29 569 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 0.907 0.791 – 1.04 0.167 218 2823 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.01 0.939 – 1.08 0.864 868 11543 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 0.868 0.696 – 1.08 0.208 80 916 exclusion phecode
287.2 Allergic purpura Hematopoietic 0.871 0.62 – 1.22 0.425 30 395 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1 0.933 – 1.08 0.951 812 10830 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 0.949 0.827 – 1.09 0.458 214 2939 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 1.26 0.881 – 1.79 0.207 32 507 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1 0.962 – 1.05 0.844 2279 27246 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 0.988 0.943 – 1.04 0.623 1930 22983 exclusion phecode
288.11 Neutropenia Hematopoietic 0.987 0.942 – 1.03 0.574 1937 23042 exclusion phecode
288.3 Eosinophilia Hematopoietic 0.994 0.728 – 1.36 0.97 40 499 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.02 0.929 – 1.12 0.692 474 6221 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.941 0.805 – 1.1 0.445 164 2167 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.04 0.992 – 1.1 0.1 1575 18736 exclusion phecode
289.5 Diseases of spleen Hematopoietic 1.08 0.961 – 1.22 0.192 291 3627 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 0.945 0.795 – 1.12 0.526 133 2006 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.05 0.761 – 1.45 0.761 38 649 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 1 0.941 – 1.07 0.928 1010 12458 exclusion phecode
290.1 Dementias Mental Disorders 0.991 0.908 – 1.08 0.844 540 6269 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 0.891 0.782 – 1.01 0.0811 252 2750 exclusion phecode
290.16 Vascular dementia Mental Disorders 1.07 0.868 – 1.32 0.524 99 1219 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 1.03 0.917 – 1.15 0.661 328 4252 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1 0.743 – 1.36 0.982 42 558 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 1 0.913 – 1.1 0.992 499 6087 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.16 0.937 – 1.43 0.176 95 1045 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.944 0.805 – 1.11 0.484 163 1978 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 0.996 0.876 – 1.13 0.951 255 3192 exclusion phecode
292 Neurological disorders Mental Disorders 1.02 0.981 – 1.06 0.322 2712 31905 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 0.994 0.929 – 1.06 0.864 906 10596 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.993 0.808 – 1.22 0.945 99 1299 exclusion phecode
292.3 Memory loss Mental Disorders 0.968 0.88 – 1.06 0.504 469 4916 exclusion phecode
292.4 Altered mental status Mental Disorders 1.02 0.959 – 1.08 0.571 1211 14671 exclusion phecode
292.6 Hallucinations Mental Disorders 1.05 0.899 – 1.22 0.562 171 2166 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.02 0.964 – 1.07 0.515 1419 15198 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 1.06 0.973 – 1.15 0.185 605 6623 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.977 0.892 – 1.07 0.625 493 6382 exclusion phecode
295.1 Schizophrenia Mental Disorders 1 0.897 – 1.12 0.944 326 4364 exclusion phecode
295.2 Paranoid disorders Mental Disorders 0.996 0.824 – 1.2 0.966 111 1363 exclusion phecode
295.3 Psychosis Mental Disorders 0.886 0.725 – 1.08 0.239 101 1317 exclusion phecode
296 Mood disorders Mental Disorders 1 0.98 – 1.03 0.797 8082 94942 exclusion phecode
296.1 Bipolar Mental Disorders 1.08 0.997 – 1.17 0.0602 632 8089 exclusion phecode
296.2 Depression Mental Disorders 0.999 0.976 – 1.02 0.928 7697 90087 exclusion phecode
296.22 Major depressive disorder Mental Disorders 0.871 0.764 – 0.994 0.0406 228 2742 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 1.02 0.885 – 1.17 0.816 208 2413 exclusion phecode
300 Anxiety disorders Mental Disorders 1.01 0.98 – 1.04 0.501 4624 51851 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.01 0.98 – 1.04 0.474 4282 47836 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 0.83 0.683 – 1.01 0.0623 109 1153 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.05 0.954 – 1.15 0.322 474 5403 exclusion phecode
300.13 Phobia Mental Disorders 1.04 0.927 – 1.16 0.53 326 3766 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.938 0.768 – 1.15 0.535 97 1080 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 0.926 0.66 – 1.3 0.657 37 419 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 0.998 0.807 – 1.23 0.987 86 965 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 0.963 0.771 – 1.2 0.742 80 891 exclusion phecode
301 Personality disorders Mental Disorders 1.04 0.907 – 1.2 0.546 203 2700 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.13 0.893 – 1.42 0.316 74 1010 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 0.94 0.804 – 1.1 0.432 162 1890 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 1 0.898 – 1.12 0.942 327 3543 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 0.993 0.873 – 1.13 0.912 252 2625 exclusion phecode
303.4 Somatoform disorder Mental Disorders 0.978 0.787 – 1.22 0.843 82 960 exclusion phecode
304 Adjustment reaction Mental Disorders 1.07 0.922 – 1.23 0.392 202 2288 exclusion phecode
305.2 Eating disorder Mental Disorders 1.01 0.8 – 1.28 0.926 73 763 exclusion phecode
306 Other mental disorder Mental Disorders 1.01 0.997 – 1.03 0.117 17030 167354 exclusion phecode
306.9 Tension headache Mental Disorders 0.984 0.861 – 1.12 0.809 218 2489 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.888 0.668 – 1.18 0.415 54 593 exclusion phecode
313.3 Autism Mental Disorders 0.922 0.666 – 1.28 0.626 39 409 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.01 0.875 – 1.17 0.888 200 2513 exclusion phecode
315.1 Learning disorder Mental Disorders 0.89 0.716 – 1.11 0.293 83 1248 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.842 0.644 – 1.1 0.21 50 615 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.02 0.984 – 1.06 0.276 3375 39026 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 1.15 0.808 – 1.63 0.442 31 449 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1 0.983 – 1.03 0.663 8591 92459 exclusion phecode
317.1 Alcoholism Mental Disorders 0.992 0.967 – 1.02 0.564 6050 64215 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.04 0.944 – 1.14 0.442 450 6050 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.01 0.992 – 1.03 0.248 11090 136722 exclusion phecode
320 Meningitis Neurological 0.976 0.871 – 1.09 0.668 314 3432 exclusion phecode
323 Encephalitis Neurological 1.02 0.9 – 1.17 0.712 242 2561 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 1.24 0.964 – 1.6 0.0928 62 590 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.08 0.928 – 1.25 0.325 186 2017 exclusion phecode
327 Sleep disorders Neurological 1.06 0.982 – 1.14 0.14 753 8299 exclusion phecode
327.3 Sleep apnea Neurological 0.992 0.953 – 1.03 0.708 2509 31613 exclusion phecode
327.4 Insomnia Neurological 1.2 0.983 – 1.46 0.0727 106 1206 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.3 1.05 – 1.62 0.0178 89 1012 exclusion phecode
331 Other cerebral degenerations Neurological 1.07 0.986 – 1.15 0.111 688 7941 exclusion phecode
331.1 Hydrocephalus Neurological 1.03 0.916 – 1.15 0.665 320 3620 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.1 0.967 – 1.25 0.146 245 2859 exclusion phecode
332 Parkinson's disease Neurological 0.995 0.92 – 1.08 0.899 696 7283 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1 0.919 – 1.09 0.974 563 6369 exclusion phecode
333.1 Essential tremor Neurological 0.954 0.795 – 1.14 0.608 119 1443 exclusion phecode
333.2 Myoclonus Neurological 1.08 0.842 – 1.38 0.551 65 700 exclusion phecode
333.4 Torsion dystonia Neurological 1.03 0.875 – 1.2 0.753 169 1872 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 0.986 0.928 – 1.05 0.649 1142 12828 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.01 0.786 – 1.29 0.959 65 836 exclusion phecode
334.2 Anterior horn cell disease Neurological 1.02 0.871 – 1.2 0.796 159 1626 exclusion phecode
335 Multiple sclerosis Neurological 0.937 0.879 – 1 0.0495 1001 10396 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.04 0.886 – 1.22 0.642 157 1874 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 0.949 0.694 – 1.3 0.745 36 467 exclusion phecode
338 Pain Neurological 1.03 0.937 – 1.13 0.556 465 5734 exclusion phecode
338.1 Acute pain Neurological 0.905 0.792 – 1.03 0.141 226 2898 exclusion phecode
338.2 Chronic pain Neurological 1.13 0.992 – 1.29 0.0655 242 2934 exclusion phecode
339 Other headache syndromes Neurological 0.993 0.965 – 1.02 0.602 5457 59083 exclusion phecode
340 Migraine Neurological 0.989 0.945 – 1.03 0.622 2104 22427 exclusion phecode
340.1 Migrain with aura Neurological 1.09 0.919 – 1.29 0.32 154 1692 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 0.897 0.773 – 1.04 0.15 196 1993 exclusion phecode
342 Hemiplegia Neurological 0.968 0.902 – 1.04 0.374 811 10529 exclusion phecode
343 Infantile cerebral palsy Neurological 0.819 0.664 – 1.01 0.0645 101 1092 exclusion phecode
344 Other paralytic syndromes Neurological 1.02 0.922 – 1.13 0.709 415 4841 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 0.972 0.939 – 1.01 0.115 3449 36984 exclusion phecode
345.1 Epilepsy Neurological 0.932 0.857 – 1.01 0.0984 600 6422 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 0.909 0.811 – 1.02 0.102 313 3237 exclusion phecode
345.12 Partial epilepsy Neurological 0.901 0.779 – 1.04 0.164 200 2113 exclusion phecode
345.3 Convulsions Neurological 0.951 0.902 – 1 0.0587 1513 16471 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 0.987 0.797 – 1.22 0.908 91 1064 exclusion phecode
348 Other conditions of brain Neurological 1.02 0.93 – 1.13 0.625 469 5731 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 0.966 0.819 – 1.14 0.683 159 2021 exclusion phecode
348.4 Cerebral cysts Neurological 0.892 0.722 – 1.1 0.286 97 1023 exclusion phecode
348.7 Coma Neurological 0.985 0.865 – 1.12 0.82 244 2540 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.2 1.02 – 1.42 0.0327 147 1803 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 0.98 0.867 – 1.11 0.749 266 2780 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.979 0.855 – 1.12 0.764 221 2482 exclusion phecode
350 Abnormal movement Neurological 0.985 0.935 – 1.04 0.574 1558 18808 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.02 0.935 – 1.11 0.647 540 6480 exclusion phecode
350.2 Abnormality of gait Neurological 0.971 0.907 – 1.04 0.405 884 10945 exclusion phecode
350.3 Lack of coordination Neurological 0.911 0.794 – 1.05 0.189 223 2634 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 1.1 0.814 – 1.49 0.534 39 397 exclusion phecode
351 Other peripheral nerve disorders Neurological 0.999 0.977 – 1.02 0.944 8509 92624 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.03 0.961 – 1.1 0.417 903 9985 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.888 0.793 – 0.994 0.0397 319 3438 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 1.08 0.988 – 1.17 0.0903 565 6376 exclusion phecode
353 Nerve root and plexus disorders Neurological 0.986 0.913 – 1.07 0.722 692 8200 exclusion phecode
353.1 Nerve plexus lesions Neurological 1.05 0.829 – 1.32 0.706 79 883 exclusion phecode
353.2 Nerve root lesions Neurological 0.848 0.618 – 1.16 0.304 36 413 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.09 0.89 – 1.34 0.395 93 1075 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.03 0.953 – 1.11 0.493 759 9463 exclusion phecode
358 Myoneural disorders Neurological 0.992 0.827 – 1.19 0.931 113 1447 exclusion phecode
358.1 Myasthenia gravis Neurological 0.991 0.821 – 1.2 0.926 105 1336 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 0.971 0.852 – 1.11 0.661 245 3358 exclusion phecode
359.1 Muscular dystrophies Neurological 0.961 0.736 – 1.25 0.77 61 888 exclusion phecode
359.2 Myopathy Neurological 0.981 0.847 – 1.14 0.795 190 2586 exclusion phecode
360 Disorders of the globe Sense Organs 1.02 0.886 – 1.16 0.825 226 2287 exclusion phecode
360.2 Progressive myopia Sense Organs 0.941 0.805 – 1.1 0.442 167 1721 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.996 0.955 – 1.04 0.863 2307 22703 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.986 0.925 – 1.05 0.677 980 9779 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.892 0.653 – 1.22 0.47 40 490 exclusion phecode
362 Other retinal disorders Sense Organs 1.02 0.977 – 1.06 0.382 2379 25973 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.05 0.992 – 1.11 0.0924 1374 14566 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.05 0.991 – 1.11 0.0994 1372 14540 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1 0.826 – 1.22 0.973 106 1132 exclusion phecode
362.31 Separation of retinal layers Sense Organs 0.944 0.75 – 1.19 0.62 76 683 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.01 0.916 – 1.1 0.91 475 5694 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 1.02 0.85 – 1.22 0.849 126 1302 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.894 0.689 – 1.16 0.395 61 584 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 1.18 0.945 – 1.48 0.142 79 801 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 1.03 0.845 – 1.26 0.758 104 1221 exclusion phecode
363.3 Chorioretinal scars Sense Organs 1.01 0.724 – 1.42 0.933 34 506 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.998 0.906 – 1.1 0.97 440 4556 exclusion phecode
364.1 Corneal opacity Sense Organs 0.894 0.685 – 1.17 0.411 58 650 exclusion phecode
364.2 Corneal edema Sense Organs 0.842 0.624 – 1.14 0.261 43 547 exclusion phecode
364.4 Corneal degenerations Sense Organs 0.88 0.744 – 1.04 0.135 149 1459 exclusion phecode
364.41 Keratoconus Sense Organs 0.838 0.65 – 1.08 0.175 66 667 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.999 0.84 – 1.19 0.992 136 1407 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 1.02 0.802 – 1.3 0.866 69 706 exclusion phecode
365 Glaucoma Sense Organs 1 0.966 – 1.04 0.842 2838 29671 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 0.955 0.883 – 1.03 0.256 674 6777 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 0.957 0.884 – 1.04 0.272 670 6746 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.02 0.926 – 1.11 0.744 477 4805 exclusion phecode
366 Cataract Sense Organs 0.99 0.972 – 1.01 0.284 12277 115766 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 1.24 0.914 – 1.68 0.167 42 517 exclusion phecode
366.2 Senile cataract Sense Organs 0.998 0.97 – 1.03 0.892 5021 54573 exclusion phecode
366.3 Traumatic cataract Sense Organs 1.05 0.818 – 1.36 0.687 69 681 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.988 0.939 – 1.04 0.642 1610 16847 exclusion phecode
367.1 Myopia Sense Organs 0.989 0.923 – 1.06 0.764 880 8778 exclusion phecode
367.2 Astigmatism Sense Organs 0.846 0.702 – 1.02 0.082 124 1340 exclusion phecode
367.8 Hypermetropia Sense Organs 1.04 0.889 – 1.22 0.608 162 1737 exclusion phecode
367.9 Blindness and low vision Sense Organs 1.02 0.927 – 1.12 0.672 439 4993 exclusion phecode
368 Visual disturbances Sense Organs 1.02 0.976 – 1.07 0.341 1896 21389 exclusion phecode
368.1 Amblyopia Sense Organs 1 0.893 – 1.12 1 320 3683 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.02 0.931 – 1.12 0.639 454 5275 exclusion phecode
368.3 Anisometropia Sense Organs 1.02 0.835 – 1.25 0.83 103 1123 exclusion phecode
368.4 Visual field defects Sense Organs 1.17 1.01 – 1.36 0.0368 209 2315 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 1.05 0.952 – 1.17 0.309 395 4538 exclusion phecode
369 Infection of the eye Sense Organs 1.1 0.985 – 1.23 0.0905 353 4013 exclusion phecode
369.2 Eye infection, viral Sense Organs 1.08 0.847 – 1.38 0.531 72 887 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 1.17 0.971 – 1.4 0.0996 131 1554 exclusion phecode
370 Keratitis Sense Organs 1.18 1.02 – 1.38 0.0307 190 2088 exclusion phecode
370.1 Corneal ulcer Sense Organs 1.14 0.921 – 1.41 0.231 97 1021 exclusion phecode
371 Inflammation of the eye Sense Organs 1.01 0.963 – 1.05 0.801 2192 22200 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 0.959 0.853 – 1.08 0.482 307 3471 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 1.01 0.957 – 1.06 0.832 1752 17237 exclusion phecode
372 Disorders of conjunctiva Sense Organs 0.988 0.904 – 1.08 0.787 529 5408 exclusion phecode
374 Other disorders of eyelids Sense Organs 0.985 0.953 – 1.02 0.36 3803 40161 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.92 0.849 – 0.997 0.0432 641 6965 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 0.995 0.938 – 1.06 0.879 1222 12800 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.986 0.936 – 1.04 0.611 1523 15626 exclusion phecode
375.2 Epiphora Sense Organs 0.973 0.898 – 1.05 0.506 636 6274 exclusion phecode
376 Disorders of the orbit Sense Organs 1.21 0.908 – 1.6 0.195 52 610 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.928 0.812 – 1.06 0.267 228 2651 exclusion phecode
377.1 Optic atrophy Sense Organs 0.857 0.616 – 1.19 0.359 34 417 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.902 0.734 – 1.11 0.327 87 959 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.997 0.933 – 1.06 0.918 958 10370 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.975 0.9 – 1.06 0.539 651 6823 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.936 0.785 – 1.12 0.463 125 1501 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.14 0.973 – 1.33 0.106 171 1962 exclusion phecode
379 Other disorders of eye Sense Organs 0.993 0.952 – 1.04 0.75 2311 25287 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 1.01 0.942 – 1.08 0.803 875 9435 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.977 0.919 – 1.04 0.467 1086 12029 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.09 0.816 – 1.45 0.566 49 522 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.01 0.891 – 1.15 0.869 262 2833 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.06 0.874 – 1.29 0.544 102 1236 exclusion phecode
380 Disorders of external ear Sense Organs 1.01 0.913 – 1.11 0.909 448 4445 exclusion phecode
380.1 Otitis externa Sense Organs 1.05 0.939 – 1.17 0.401 342 3761 exclusion phecode
380.4 Impacted cerumen Sense Organs 0.964 0.847 – 1.1 0.577 250 2575 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.04 0.983 – 1.1 0.18 1414 15684 exclusion phecode
381.1 Otitis media Sense Organs 1.05 0.994 – 1.12 0.0798 1156 12856 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.07 0.984 – 1.17 0.109 553 6278 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 1.18 0.987 – 1.4 0.0699 135 1457 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 0.921 0.765 – 1.11 0.381 113 1243 exclusion phecode
381.9 Otorrhea Sense Organs 0.886 0.761 – 1.03 0.116 185 2030 exclusion phecode
382 Otalgia Sense Organs 1.06 0.921 – 1.21 0.429 219 2306 exclusion phecode
383 Otosclerosis Sense Organs 0.988 0.864 – 1.13 0.861 232 2353 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 0.975 0.912 – 1.04 0.459 919 9595 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 0.966 0.896 – 1.04 0.365 732 7653 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.01 0.92 – 1.1 0.892 527 5736 exclusion phecode
385.3 Cholesteatoma Sense Organs 0.978 0.883 – 1.08 0.679 400 4423 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.14 0.976 – 1.33 0.0997 170 1806 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.04 0.975 – 1.1 0.254 1156 12518 exclusion phecode
386.1 Meniere's disease Sense Organs 1.03 0.929 – 1.15 0.552 369 4126 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 1 0.881 – 1.14 0.961 250 2655 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.02 0.934 – 1.12 0.64 515 5560 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.02 0.979 – 1.06 0.376 2850 32587 exclusion phecode
388 Other disorders of ear Sense Organs 1.09 0.922 – 1.3 0.302 141 1463 exclusion phecode
389 Hearing loss Sense Organs 1 0.964 – 1.04 0.873 2628 29264 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 0.884 0.786 – 0.994 0.0386 296 3179 exclusion phecode
389.2 Conductive hearing loss Sense Organs 1.08 0.961 – 1.22 0.193 296 3354 exclusion phecode
389.4 Tinnitus Sense Organs 1.03 0.919 – 1.15 0.621 336 3644 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 0.999 0.961 – 1.04 0.98 2638 32790 exclusion phecode
394.2 Mitral valve disease Circulatory System 0.986 0.938 – 1.04 0.577 1639 20116 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.05 0.966 – 1.13 0.274 661 8535 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 0.949 0.871 – 1.03 0.234 555 7030 exclusion phecode
395 Heart valve disorders Circulatory System 0.997 0.955 – 1.04 0.899 2254 28234 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 0.998 0.948 – 1.05 0.93 1586 19409 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 0.986 0.825 – 1.18 0.877 132 1822 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.14 0.875 – 1.49 0.332 57 709 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.884 0.674 – 1.16 0.372 51 657 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.01 0.94 – 1.09 0.735 743 9813 exclusion phecode
396 Abnormal heart sounds Circulatory System 1 0.929 – 1.08 0.92 700 7655 exclusion phecode
401 Hypertension Circulatory System 0.991 0.981 – 1 0.115 43185 207901 exclusion phecode
401.1 Essential hypertension Circulatory System 0.992 0.981 – 1 0.12 43131 207712 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.01 0.909 – 1.12 0.845 349 13252 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.02 0.865 – 1.19 0.853 157 2564 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.02 0.885 – 1.17 0.788 192 10832 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.3 0.925 – 1.83 0.13 29 1048 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.01 0.946 – 1.08 0.704 908 10889 exclusion phecode
411 Ischemic Heart Disease Circulatory System 0.996 0.981 – 1.01 0.632 17437 150784 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 0.998 0.96 – 1.04 0.909 2818 35061 exclusion phecode
411.2 Myocardial infarction Circulatory System 0.997 0.971 – 1.02 0.792 6320 76419 exclusion phecode
411.3 Angina pectoris Circulatory System 0.997 0.975 – 1.02 0.756 8723 98965 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 0.998 0.979 – 1.02 0.831 11218 107549 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.952 0.864 – 1.05 0.326 424 4851 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.999 0.976 – 1.02 0.92 7773 89870 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 0.984 0.911 – 1.06 0.672 695 8291 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 1.04 0.974 – 1.12 0.227 879 12319 exclusion phecode
414.2 ASCVD Circulatory System 1.17 0.86 – 1.58 0.322 38 477 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.01 0.965 – 1.05 0.785 2401 31183 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.739 0.529 – 1.03 0.0765 44 513 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 0.941 0.833 – 1.06 0.332 266 4029 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 0.92 0.799 – 1.06 0.246 197 3027 exclusion phecode
416 Cardiomegaly Circulatory System 1.01 0.959 – 1.07 0.628 1300 17990 exclusion phecode
418 Nonspecific chest pain Circulatory System 1 0.985 – 1.02 0.998 18523 198416 exclusion phecode
418.1 Precordial pain Circulatory System 1.01 0.965 – 1.05 0.745 2284 25880 exclusion phecode
420 Carditis Circulatory System 1.04 0.981 – 1.1 0.185 1212 14499 exclusion phecode
420.1 Myocarditis Circulatory System 1.02 0.811 – 1.27 0.886 74 906 exclusion phecode
420.2 Pericarditis Circulatory System 1.01 0.944 – 1.09 0.689 783 9266 exclusion phecode
420.21 Acute pericarditis Circulatory System 1 0.851 – 1.18 0.971 152 1553 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.19 0.926 – 1.53 0.175 62 736 exclusion phecode
420.3 Endocarditis Circulatory System 1.12 1.01 – 1.24 0.0339 400 4851 exclusion phecode
425 Cardiomyopathy Circulatory System 0.972 0.895 – 1.06 0.496 608 8768 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.966 0.889 – 1.05 0.417 596 8515 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.04 0.807 – 1.35 0.747 68 931 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 0.882 0.709 – 1.1 0.259 89 1171 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.21 0.818 – 1.79 0.342 28 403 exclusion phecode
426 Cardiac conduction disorders Circulatory System 0.986 0.954 – 1.02 0.399 3814 46144 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 0.995 0.937 – 1.06 0.878 1125 13826 exclusion phecode
426.21 First degree AV block Circulatory System 0.966 0.884 – 1.06 0.447 527 6397 exclusion phecode
426.23 Second degree AV block Circulatory System 0.998 0.883 – 1.13 0.97 268 2957 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 1.02 0.903 – 1.14 0.782 289 3853 exclusion phecode
426.25 Other heart block Circulatory System 1.04 0.822 – 1.31 0.756 75 868 exclusion phecode
426.3 Bundle branch block Circulatory System 0.997 0.95 – 1.05 0.887 1850 22379 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.02 0.952 – 1.1 0.551 840 10047 exclusion phecode
426.32 Left bundle branch block Circulatory System 0.995 0.932 – 1.06 0.893 947 11678 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.878 0.749 – 1.03 0.109 163 1747 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.11 0.804 – 1.54 0.524 38 404 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.959 0.905 – 1.02 0.15 1258 16287 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.965 0.909 – 1.02 0.249 1155 14951 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 0.998 0.981 – 1.02 0.861 14168 146668 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 0.987 0.943 – 1.03 0.583 1998 22708 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.973 0.924 – 1.03 0.309 1538 16947 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.963 0.88 – 1.05 0.406 501 6314 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.01 0.988 – 1.03 0.347 7861 90141 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 1 0.955 – 1.05 0.971 1921 22082 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.986 0.907 – 1.07 0.751 591 8043 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 1 0.862 – 1.16 0.997 190 2342 exclusion phecode
427.42 Cardiac arrest Circulatory System 1 0.914 – 1.1 0.949 476 6663 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.93 0.851 – 1.02 0.104 554 6551 exclusion phecode
427.6 Premature beats Circulatory System 1.08 0.969 – 1.21 0.163 333 3786 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 0.823 0.652 – 1.04 0.101 73 831 exclusion phecode
427.7 Tachycardia NOS Circulatory System 0.969 0.917 – 1.03 0.277 1309 15806 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 0.939 0.827 – 1.07 0.334 247 2726 exclusion phecode
427.9 Palpitations Circulatory System 0.98 0.942 – 1.02 0.313 2672 28419 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.06 1.02 – 1.1 0.00718 2359 36584 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.04 0.962 – 1.12 0.345 713 13567 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.06 1.01 – 1.11 0.0136 1894 29081 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.01 0.923 – 1.11 0.773 462 5073 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 1.07 0.703 – 1.62 0.763 19 447 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.943 0.845 – 1.05 0.291 336 3689 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.22 1.02 – 1.46 0.0268 126 1424 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1 0.945 – 1.06 0.936 1172 13327 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.05 0.965 – 1.14 0.256 569 6142 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 0.938 0.852 – 1.03 0.195 439 5232 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.02 0.863 – 1.2 0.843 150 1749 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.01 0.978 – 1.04 0.648 4755 58932 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.04 0.955 – 1.13 0.382 603 7600 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.04 0.868 – 1.25 0.672 123 1453 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.998 0.956 – 1.04 0.936 2213 28187 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.979 0.913 – 1.05 0.548 850 11261 exclusion phecode
433.3 Cerebral ischemia Circulatory System 0.993 0.944 – 1.05 0.801 1585 19448 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1 0.943 – 1.06 0.983 1181 14450 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.01 0.89 – 1.14 0.891 260 2923 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.919 0.848 – 0.996 0.04 632 8793 exclusion phecode
440 Atherosclerosis Circulatory System 1.02 0.937 – 1.1 0.682 602 8853 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.47 0.981 – 2.21 0.0621 23 734 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 1.03 0.932 – 1.15 0.52 365 5154 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 0.855 0.718 – 1.02 0.078 137 1851 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 1.11 0.986 – 1.24 0.0855 315 4192 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 1.01 0.851 – 1.2 0.902 140 1944 exclusion phecode
442 Other aneurysm Circulatory System 1.03 0.959 – 1.1 0.443 871 12071 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.01 0.928 – 1.09 0.869 611 9043 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 0.982 0.879 – 1.1 0.754 317 5469 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.36 0.959 – 1.92 0.0842 33 605 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.928 0.747 – 1.15 0.496 87 1106 exclusion phecode
442.4 Arterial dissection Circulatory System 1.39 1.02 – 1.9 0.0377 40 411 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.05 0.868 – 1.26 0.63 121 1440 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.03 0.98 – 1.07 0.276 1934 26801 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.01 0.932 – 1.08 0.895 753 8551 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1 0.83 – 1.21 0.979 111 2583 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1.03 0.984 – 1.08 0.199 1857 25181 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 1.05 0.986 – 1.11 0.135 1122 16871 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1 0.911 – 1.11 0.936 423 6204 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.07 0.936 – 1.21 0.336 236 3651 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.07 0.969 – 1.19 0.172 395 5738 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 1.07 0.853 – 1.34 0.568 81 1295 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.12 0.977 – 1.29 0.103 206 2622 exclusion phecode
446.9 Arteritis NOS Circulatory System 0.977 0.806 – 1.18 0.809 106 1715 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.04 0.959 – 1.13 0.34 621 8868 exclusion phecode
447.1 Stricture of artery Circulatory System 1.06 0.963 – 1.18 0.222 397 5654 exclusion phecode
448 Disease of capillaries Circulatory System 1.04 0.837 – 1.29 0.725 86 1027 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 0.935 0.843 – 1.04 0.204 381 5156 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.01 0.966 – 1.05 0.716 2252 27957 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.01 0.965 – 1.06 0.682 2088 25960 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 0.953 0.847 – 1.07 0.43 305 4118 exclusion phecode
454 Varicose veins Circulatory System 1.01 0.99 – 1.04 0.286 8006 83774 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1.01 0.992 – 1.04 0.213 8287 85950 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.944 0.847 – 1.05 0.302 338 4442 exclusion phecode
455 Hemorrhoids Circulatory System 1.02 1 – 1.03 0.0444 16487 171594 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.23 0.993 – 1.53 0.0576 85 1265 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 0.888 0.694 – 1.14 0.349 69 663 exclusion phecode
458 Hypotension Circulatory System 1.03 0.993 – 1.07 0.111 3122 40224 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 0.986 0.913 – 1.07 0.729 676 8957 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 0.962 0.799 – 1.16 0.683 118 1585 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.04 0.991 – 1.09 0.11 1883 24554 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.02 0.994 – 1.04 0.151 8927 112673 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 1.31 1.03 – 1.65 0.0267 74 993 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.01 0.993 – 1.04 0.182 8849 111669 exclusion phecode
464 Acute sinusitis Respiratory 0.987 0.827 – 1.18 0.883 131 1476 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.928 0.881 – 0.978 0.00537 1510 16828 exclusion phecode
465.2 Acute pharyngitis Respiratory 0.975 0.895 – 1.06 0.56 553 6196 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.737 0.608 – 0.893 0.00183 110 1204 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.03 0.993 – 1.06 0.116 3440 34890 exclusion phecode
471 Nasal polyps Respiratory 1.02 0.98 – 1.07 0.311 2359 23487 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.02 0.94 – 1.1 0.68 694 7120 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.02 0.966 – 1.07 0.539 1688 18166 exclusion phecode
473.1 Chronic laryngitis Respiratory 1.08 0.841 – 1.38 0.553 64 747 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.945 0.809 – 1.1 0.48 172 1889 exclusion phecode
473.4 Voice disturbance Respiratory 0.982 0.909 – 1.06 0.641 706 7600 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 0.989 0.934 – 1.05 0.688 1361 14138 exclusion phecode
474.1 Acute tonsillitis Respiratory 0.984 0.89 – 1.09 0.744 426 4455 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 0.964 0.899 – 1.03 0.301 868 8975 exclusion phecode
475 Chronic sinusitis Respiratory 1 0.956 – 1.05 0.912 1842 19122 exclusion phecode
476 Allergic rhinitis Respiratory 0.966 0.899 – 1.04 0.348 804 7930 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.03 0.974 – 1.08 0.324 1468 16711 exclusion phecode
478 Throat pain Respiratory 0.894 0.791 – 1.01 0.0725 269 2775 exclusion phecode
479 Other upper respiratory disease Respiratory 1.03 0.987 – 1.07 0.201 2863 29922 exclusion phecode
480 Pneumonia Respiratory 1.01 0.987 – 1.04 0.311 5640 71497 exclusion phecode
480.1 Bacterial pneumonia Respiratory 0.993 0.96 – 1.03 0.669 3627 46061 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1 0.969 – 1.04 0.79 3210 40833 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 1.1 0.807 – 1.49 0.552 46 634 exclusion phecode
480.2 Viral pneumonia Respiratory 1.18 0.869 – 1.61 0.285 39 522 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.03 0.755 – 1.41 0.848 42 678 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1.05 0.949 – 1.16 0.359 423 5257 exclusion phecode
481 Influenza Respiratory 0.916 0.791 – 1.06 0.243 191 2422 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.01 0.833 – 1.21 0.952 116 1405 exclusion phecode
495 Asthma Respiratory 1 0.986 – 1.02 0.852 17338 187928 exclusion phecode
495.2 Asthma with exacerbation Respiratory 1.04 0.882 – 1.22 0.648 164 1912 exclusion phecode
496 Chronic airway obstruction Respiratory 1.01 0.978 – 1.03 0.685 5308 69214 exclusion phecode
496.1 Emphysema Respiratory 1.01 0.942 – 1.08 0.778 851 11564 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.01 0.952 – 1.06 0.806 1317 19655 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.01 0.951 – 1.07 0.768 1184 17996 exclusion phecode
496.3 Bronchiectasis Respiratory 0.974 0.916 – 1.03 0.394 1112 13006 exclusion phecode
497 Bronchitis Respiratory 0.93 0.834 – 1.04 0.195 345 4518 exclusion phecode
500 Lung disease due to external agents Respiratory 1.15 0.996 – 1.33 0.0565 190 2563 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.18 0.857 – 1.62 0.312 37 557 exclusion phecode
500.2 Pneumoconiosis Respiratory 1.23 1.01 – 1.49 0.037 105 1418 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.01 0.901 – 1.13 0.848 319 4401 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 0.98 0.888 – 1.08 0.687 411 6032 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 0.955 0.826 – 1.1 0.53 188 3519 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 0.963 0.816 – 1.14 0.652 142 2260 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 0.949 0.668 – 1.35 0.772 34 435 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.1 1.02 – 1.19 0.0151 651 8026 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 0.994 0.961 – 1.03 0.743 3569 43880 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 1 0.943 – 1.06 0.97 1123 13891 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 0.987 0.931 – 1.05 0.667 1185 17527 exclusion phecode
509.1 Respiratory failure Respiratory 1.02 0.958 – 1.1 0.475 923 13859 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.03 0.962 – 1.11 0.37 807 12198 exclusion phecode
509.5 Respiratory arrest Respiratory 0.947 0.75 – 1.2 0.646 74 1008 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 0.804 0.694 – 0.932 0.0038 184 2579 exclusion phecode
510 Other diseases of lung Respiratory 1.01 0.915 – 1.11 0.862 432 5174 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.01 0.984 – 1.04 0.415 5300 64335 exclusion phecode
512.1 Wheezing Respiratory 1.1 0.916 – 1.32 0.305 126 1550 exclusion phecode
512.2 Painful respiration Respiratory 1.11 0.937 – 1.32 0.224 140 1523 exclusion phecode
512.7 Shortness of breath Respiratory 1.01 0.976 – 1.05 0.532 3323 41531 exclusion phecode
512.8 Cough Respiratory 1.03 0.978 – 1.08 0.282 1711 20522 exclusion phecode
512.9 Other dyspnea Respiratory 0.945 0.865 – 1.03 0.208 532 6453 exclusion phecode
513 Respiratory abnormalities Respiratory 0.885 0.794 – 0.987 0.028 344 4276 exclusion phecode
513.3 Hypoventilation Respiratory 1.36 0.953 – 1.93 0.09 31 572 exclusion phecode
513.4 Hyperventilation Respiratory 0.877 0.753 – 1.02 0.0936 173 2037 exclusion phecode
513.8 Disorders of diaphragm Respiratory 0.769 0.624 – 0.947 0.0135 94 1002 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.05 0.99 – 1.11 0.106 1360 16815 exclusion phecode
516 Abnormal sputum Respiratory 1.04 0.981 – 1.1 0.18 1221 14739 exclusion phecode
516.1 Hemoptysis Respiratory 1.04 0.983 – 1.11 0.166 1196 14347 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.01 0.987 – 1.04 0.3 5349 66112 exclusion phecode
519.2 Respiratory complications Respiratory 1.03 0.871 – 1.21 0.762 149 2197 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.01 0.984 – 1.04 0.375 5049 62577 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.984 0.857 – 1.13 0.819 216 2189 exclusion phecode
520 Disorders of tooth development Digestive 1.02 0.965 – 1.07 0.556 1587 16220 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.991 0.696 – 1.41 0.958 33 402 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 0.996 0.95 – 1.04 0.871 1872 18920 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.04 0.991 – 1.09 0.113 1978 22781 exclusion phecode
521.1 Dental caries Digestive 1.03 0.988 – 1.08 0.148 1980 22849 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.04 0.981 – 1.1 0.197 1276 13546 exclusion phecode
522.5 Periapical abscess Digestive 1.05 0.979 – 1.13 0.166 834 8939 exclusion phecode
523 Gingival and periodontal diseases Digestive 0.996 0.939 – 1.06 0.901 1208 12891 exclusion phecode
523.1 Gingivitis Digestive 1.07 0.847 – 1.36 0.553 73 795 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 0.993 0.925 – 1.06 0.838 859 9141 exclusion phecode
523.31 Acute periodontitis Digestive 0.99 0.903 – 1.09 0.828 499 5333 exclusion phecode
523.32 Chronic periodontitis Digestive 0.994 0.897 – 1.1 0.903 405 4296 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 0.98 0.86 – 1.12 0.754 250 2629 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 0.969 0.848 – 1.11 0.641 230 2442 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.952 0.906 – 0.999 0.046 1776 19685 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 0.876 0.666 – 1.15 0.343 55 521 exclusion phecode
526 Diseases of the jaws Digestive 0.991 0.915 – 1.07 0.821 657 7001 exclusion phecode
526.1 Cysts of the jaws Digestive 1.02 0.898 – 1.17 0.717 234 2404 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 0.995 0.761 – 1.3 0.971 49 473 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 0.94 0.803 – 1.1 0.446 168 1904 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 0.936 0.798 – 1.1 0.417 164 1846 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 0.981 0.767 – 1.25 0.877 75 816 exclusion phecode
526.9 Jaw disease NOS Digestive 1 0.85 – 1.18 0.997 158 1726 exclusion phecode
527 Diseases of the salivary glands Digestive 0.988 0.897 – 1.09 0.808 455 5107 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 0.924 0.712 – 1.2 0.551 54 601 exclusion phecode
527.2 Sialoadenitis Digestive 1.05 0.918 – 1.19 0.498 240 2739 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 0.865 0.625 – 1.2 0.382 42 460 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 0.937 0.749 – 1.17 0.566 84 875 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1.03 0.992 – 1.07 0.12 2634 28527 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.06 0.941 – 1.19 0.338 301 3440 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.1 0.963 – 1.25 0.164 248 2842 exclusion phecode
528.12 Oral aphthae Digestive 0.938 0.713 – 1.23 0.644 56 628 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.17 0.966 – 1.42 0.108 114 1341 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 0.984 0.794 – 1.22 0.883 90 909 exclusion phecode
528.41 Cyst of the salivary gland Digestive 1.04 0.811 – 1.34 0.745 65 703 exclusion phecode
528.5 Diseases of lips Digestive 0.995 0.904 – 1.1 0.921 474 5001 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 0.907 0.784 – 1.05 0.186 194 2174 exclusion phecode
528.7 Sialolithiasis Digestive 0.975 0.85 – 1.12 0.72 219 2313 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 0.97 0.903 – 1.04 0.405 829 9018 exclusion phecode
529.1 Glossitis Digestive 1.05 0.906 – 1.23 0.494 186 2166 exclusion phecode
530 Diseases of esophagus Digestive 1.01 0.996 – 1.02 0.145 21728 206908 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.01 0.998 – 1.03 0.0981 20403 201209 exclusion phecode
530.11 GERD Digestive 1.01 0.989 – 1.02 0.517 14956 164974 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.04 0.999 – 1.07 0.0546 3155 35906 exclusion phecode
530.14 Reflux esophagitis Digestive 1.03 1 – 1.05 0.0249 6827 75648 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1.01 0.949 – 1.08 0.678 943 11936 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1.02 0.956 – 1.08 0.622 1178 12933 exclusion phecode
530.5 Disorders of esophageal motility Digestive 0.952 0.859 – 1.06 0.349 399 4577 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 0.907 0.739 – 1.11 0.349 101 1024 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.879 0.764 – 1.01 0.0719 215 2522 exclusion phecode
530.9 Heartburn Digestive 0.979 0.928 – 1.03 0.426 1495 15580 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.983 0.953 – 1.01 0.295 4226 49668 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.955 0.859 – 1.06 0.398 352 4319 exclusion phecode
531.2 Gastric ulcer Digestive 0.982 0.943 – 1.02 0.395 2423 28820 exclusion phecode
531.3 Duodenal ulcer Digestive 1 0.955 – 1.05 0.954 1799 20881 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 0.965 0.846 – 1.1 0.602 239 2939 exclusion phecode
532 Dysphagia Digestive 0.991 0.96 – 1.02 0.578 4228 46637 exclusion phecode
535 Gastritis and duodenitis Digestive 0.999 0.984 – 1.01 0.917 18173 191285 exclusion phecode
535.1 Acute gastritis Digestive 1.06 0.98 – 1.14 0.146 717 8385 exclusion phecode
535.2 Atrophic gastritis Digestive 1.04 0.906 – 1.19 0.599 234 2533 exclusion phecode
535.6 Duodenitis Digestive 1 0.971 – 1.03 0.981 4682 54128 exclusion phecode
535.8 Other specified gastritis Digestive 0.992 0.964 – 1.02 0.561 5239 57860 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.03 0.822 – 1.29 0.805 83 858 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 0.955 0.82 – 1.11 0.551 175 1868 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.01 0.961 – 1.05 0.828 2045 24138 exclusion phecode
540 Appendiceal conditions Digestive 1 0.959 – 1.05 0.938 2266 23459 exclusion phecode
540.1 Appendicitis Digestive 1 0.96 – 1.05 0.875 2134 21972 exclusion phecode
540.11 Acute appendicitis Digestive 1 0.958 – 1.05 0.854 1944 19778 exclusion phecode
550 Abdominal hernia Digestive 1.01 1 – 1.03 0.02 29510 211276 exclusion phecode
550.1 Inguinal hernia Digestive 1.01 0.989 – 1.03 0.348 10584 84628 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.02 1 – 1.03 0.022 16946 174899 exclusion phecode
550.3 Femoral hernia Digestive 0.929 0.848 – 1.02 0.118 492 4835 exclusion phecode
550.4 Umbilical hernia Digestive 1.03 0.987 – 1.08 0.178 2206 26237 exclusion phecode
550.5 Ventral hernia Digestive 1 0.961 – 1.05 0.837 2061 24752 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.02 0.982 – 1.06 0.307 2931 33097 exclusion phecode
555.1 Regional enteritis Digestive 0.992 0.933 – 1.05 0.806 1107 13156 exclusion phecode
555.2 Ulcerative colitis Digestive 1.02 0.978 – 1.07 0.335 2119 23491 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 0.969 0.875 – 1.07 0.543 381 4097 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1 0.927 – 1.08 0.953 693 7778 exclusion phecode
556.1 Ulceration of intestine Digestive 1.02 0.927 – 1.13 0.63 429 4916 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.924 0.8 – 1.07 0.283 198 2289 exclusion phecode
557.1 Celiac disease Digestive 0.891 0.841 – 0.944 7.92e-05 1289 13848 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.02 1 – 1.05 0.0196 10139 116051 exclusion phecode
559 Ileostomy status Digestive 0.955 0.895 – 1.02 0.162 998 11716 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.01 0.966 – 1.05 0.769 2534 28294 exclusion phecode
560.1 Paralytic ileus Digestive 1.08 0.97 – 1.21 0.155 318 3637 exclusion phecode
560.2 Impaction of intestine Digestive 0.961 0.819 – 1.13 0.629 165 1951 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 1.05 0.965 – 1.15 0.25 547 6023 exclusion phecode
560.4 Other intestinal obstruction Digestive 1 0.958 – 1.05 0.983 2181 24215 exclusion phecode
561 Symptoms involving digestive system Digestive 0.996 0.976 – 1.02 0.652 11071 118093 exclusion phecode
561.1 Diarrhea Digestive 0.891 0.794 – 0.999 0.0489 307 3348 exclusion phecode
561.2 Flatulence Digestive 0.965 0.91 – 1.02 0.232 1188 12682 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 0.997 0.981 – 1.01 0.667 17018 154122 exclusion phecode
562.1 Diverticulosis Digestive 0.997 0.981 – 1.01 0.666 16988 154070 exclusion phecode
563 Constipation Digestive 1.01 0.98 – 1.03 0.68 6720 75745 exclusion phecode
564 Functional digestive disorders Digestive 1 0.985 – 1.02 0.798 14222 154657 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1 0.969 – 1.03 0.97 4007 42741 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.07 1.01 – 1.14 0.0326 1036 11923 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 0.997 0.977 – 1.02 0.78 9638 108537 exclusion phecode
565 Anal and rectal conditions Digestive 1 0.981 – 1.02 0.873 10014 106323 exclusion phecode
565.1 Anal and rectal polyp Digestive 0.998 0.969 – 1.03 0.905 4897 51529 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.01 0.923 – 1.1 0.839 519 6610 exclusion phecode
568 Other disorders of peritoneum Digestive 1.03 0.988 – 1.08 0.15 2143 24137 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.03 0.987 – 1.08 0.17 2045 22970 exclusion phecode
569 Other disorders of intestine Digestive 0.991 0.953 – 1.03 0.667 2686 29901 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.939 0.757 – 1.16 0.565 94 1003 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.03 0.921 – 1.16 0.595 318 3425 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.01 0.957 – 1.06 0.771 1504 21458 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.01 0.945 – 1.08 0.787 944 12403 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.696 0.532 – 0.911 0.00838 55 810 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.06 0.875 – 1.29 0.542 105 1910 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.04 0.948 – 1.15 0.379 430 6942 exclusion phecode
571.81 Portal hypertension Digestive 1.04 0.912 – 1.2 0.528 214 3717 exclusion phecode
572 Ascites (non malignant) Digestive 0.989 0.923 – 1.06 0.763 870 11009 exclusion phecode
573 Other disorders of liver Digestive 0.996 0.929 – 1.07 0.902 842 10720 exclusion phecode
573.2 Liver replaced by transplant Digestive 0.609 0.39 – 0.952 0.0295 15 719 exclusion phecode
573.3 Hepatomegaly Digestive 1.02 0.861 – 1.2 0.834 145 2103 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.06 0.968 – 1.16 0.212 498 6264 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 0.987 0.943 – 1.03 0.556 2045 24822 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.03 0.864 – 1.24 0.711 118 1416 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.03 1.01 – 1.05 0.0121 9995 116039 exclusion phecode
574.1 Cholelithiasis Digestive 1.02 0.999 – 1.04 0.0625 8674 100916 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.975 0.911 – 1.04 0.461 915 10927 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.02 0.985 – 1.05 0.277 3535 40608 exclusion phecode
574.2 Calculus of bile duct Digestive 1.03 0.979 – 1.09 0.243 1591 19218 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.04 0.985 – 1.09 0.169 1684 20184 exclusion phecode
575 Other biliary tract disease Digestive 1.01 0.966 – 1.05 0.758 2417 28197 exclusion phecode
575.1 Cholangitis Digestive 0.957 0.843 – 1.09 0.491 246 3359 exclusion phecode
575.2 Obstruction of bile duct Digestive 0.948 0.863 – 1.04 0.262 469 5513 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.999 0.893 – 1.12 0.989 329 3555 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.06 0.994 – 1.14 0.0753 903 10419 exclusion phecode
575.8 Other disorders of biliary tract Digestive 0.964 0.889 – 1.05 0.38 629 7533 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.06 0.919 – 1.22 0.424 201 2448 exclusion phecode
577 Diseases of pancreas Digestive 1.06 1.01 – 1.12 0.0198 1539 18975 exclusion phecode
577.1 Acute pancreatitis Digestive 1.08 1.01 – 1.14 0.0163 1156 14294 exclusion phecode
577.2 Chronic pancreatitis Digestive 0.935 0.83 – 1.05 0.273 289 3652 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.02 0.886 – 1.17 0.813 214 2618 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.02 0.999 – 1.03 0.0709 14019 150844 exclusion phecode
578.1 Hematemesis Digestive 0.955 0.899 – 1.02 0.143 1103 13997 exclusion phecode
578.2 Blood in stool Digestive 1.03 0.978 – 1.08 0.267 1574 18437 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.02 1 – 1.05 0.0297 9164 96331 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.995 0.962 – 1.03 0.773 3559 38564 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 0.972 0.909 – 1.04 0.412 915 11399 exclusion phecode
579.2 Splenomegaly Digestive 1.04 0.892 – 1.22 0.609 164 2991 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.03 0.971 – 1.1 0.307 1127 11968 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.09 0.973 – 1.22 0.139 320 10528 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.04 0.903 – 1.2 0.568 189 7088 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1.12 0.72 – 1.73 0.623 18 560 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 1.31 0.949 – 1.8 0.101 37 957 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 0.979 0.831 – 1.15 0.804 140 5813 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.15 0.954 – 1.38 0.143 113 3276 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.2 0.95 – 1.51 0.127 66 1741 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.17 0.928 – 1.47 0.185 67 1798 exclusion phecode
585 Renal failure Genitourinary 1.04 0.995 – 1.08 0.0817 2224 47440 exclusion phecode
585.1 Acute renal failure Genitourinary 1.03 0.981 – 1.08 0.224 1647 30586 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.05 0.95 – 1.16 0.343 407 10013 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.07 0.975 – 1.18 0.155 445 17878 exclusion phecode
585.31 Renal dialysis Genitourinary 1.07 0.842 – 1.36 0.583 67 3525 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.03 0.979 – 1.08 0.256 1613 23513 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.23 0.936 – 1.62 0.137 46 1460 exclusion phecode
586.11 Small kidney Genitourinary 1.22 0.909 – 1.65 0.182 38 1242 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.04 0.96 – 1.12 0.343 653 8642 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.16 0.81 – 1.66 0.415 26 569 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.04 0.951 – 1.15 0.369 473 6532 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.22 0.826 – 1.79 0.322 24 2697 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 0.883 0.584 – 1.33 0.555 21 735 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 1.14 0.849 – 1.52 0.387 42 808 exclusion phecode
590 Pyelonephritis Genitourinary 1.02 0.949 – 1.1 0.59 801 10146 exclusion phecode
591 Urinary tract infection Genitourinary 0.999 0.976 – 1.02 0.947 7516 88690 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.02 0.973 – 1.07 0.42 1928 21171 exclusion phecode
592.1 Cystitis Genitourinary 1.02 0.975 – 1.07 0.375 1886 20769 exclusion phecode
592.11 Acute cystitis Genitourinary 0.996 0.795 – 1.25 0.976 86 944 exclusion phecode
592.12 Chronic cystitis Genitourinary 0.997 0.916 – 1.09 0.944 577 6386 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 0.857 0.735 – 0.998 0.0478 173 1820 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.09 0.909 – 1.3 0.362 121 1186 exclusion phecode
593 Hematuria Genitourinary 0.997 0.977 – 1.02 0.765 10355 112993 exclusion phecode
594 Urinary calculus Genitourinary 1.02 0.99 – 1.06 0.17 3976 45158 exclusion phecode
594.1 Calculus of kidney Genitourinary 1.03 0.986 – 1.08 0.17 1936 22297 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 1.05 0.952 – 1.16 0.318 430 5060 exclusion phecode
594.3 Calculus of ureter Genitourinary 1.03 0.973 – 1.08 0.345 1479 17012 exclusion phecode
594.8 Renal colic Genitourinary 1.01 0.953 – 1.07 0.776 1333 14789 exclusion phecode
595 Hydronephrosis Genitourinary 1.02 0.955 – 1.08 0.624 1061 13692 exclusion phecode
596 Other disorders of bladder Genitourinary 1.01 0.979 – 1.03 0.687 6147 66514 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 0.967 0.912 – 1.03 0.267 1187 12461 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 0.995 0.935 – 1.06 0.878 1093 12035 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.03 0.985 – 1.07 0.214 2569 27514 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.02 0.977 – 1.07 0.35 2151 23144 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.11 0.815 – 1.51 0.506 38 544 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.05 1.01 – 1.1 0.0243 2262 24317 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.05 0.89 – 1.23 0.574 158 2095 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.02 1 – 1.04 0.029 12379 133880 exclusion phecode
599.1 Urinary obstruction Genitourinary 0.941 0.746 – 1.19 0.605 79 1139 exclusion phecode
599.2 Retention of urine Genitourinary 1.02 0.986 – 1.05 0.262 3915 44012 exclusion phecode
599.3 Dysuria Genitourinary 0.939 0.872 – 1.01 0.0933 767 8611 exclusion phecode
599.4 Urinary incontinence Genitourinary 1.03 1 – 1.05 0.0485 6225 66676 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.01 0.969 – 1.05 0.686 2659 28363 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.01 0.727 – 1.39 0.974 37 695 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 1.02 0.747 – 1.38 0.919 37 432 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1.03 0.968 – 1.09 0.38 1246 13115 exclusion phecode
600 Hyperplasia of prostate Genitourinary 1.02 0.994 – 1.05 0.127 6386 55946 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 1.01 0.957 – 1.07 0.645 1239 13404 exclusion phecode
601.1 Prostatitis Genitourinary 1.01 0.943 – 1.08 0.833 935 9926 exclusion phecode
601.11 Acute prostatitis Genitourinary 1.07 0.902 – 1.27 0.439 135 1527 exclusion phecode
601.12 Chronic prostatitis Genitourinary 0.98 0.898 – 1.07 0.65 548 5689 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 1.03 0.752 – 1.41 0.847 45 421 exclusion phecode
601.4 Balanoposthitis Genitourinary 1.01 0.867 – 1.18 0.904 179 1907 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.998 0.851 – 1.17 0.981 168 2013 exclusion phecode
602 Other disorders of prostate Genitourinary 0.991 0.922 – 1.07 0.81 787 8223 exclusion phecode
603 Other disorders of testis Genitourinary 0.939 0.888 – 0.993 0.0268 1349 14624 exclusion phecode
603.1 Hydrocele Genitourinary 0.942 0.877 – 1.01 0.0985 832 8911 exclusion phecode
604 Disorders of penis Genitourinary 1.03 0.983 – 1.08 0.226 2065 22593 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 1.01 0.963 – 1.06 0.625 1692 18724 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 1.03 0.879 – 1.2 0.723 168 1816 exclusion phecode
608 Other disorders of male genital organs Genitourinary 0.965 0.919 – 1.01 0.148 1823 19075 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 0.946 0.791 – 1.13 0.539 135 1361 exclusion phecode
609.1 Infertility, male Genitourinary 0.969 0.723 – 1.3 0.832 49 503 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 0.944 0.765 – 1.17 0.592 99 1002 exclusion phecode
610 Benign mammary dysplasias Genitourinary 1.01 0.966 – 1.06 0.606 1972 19921 exclusion phecode
610.1 Cystic mastopathy Genitourinary 1.05 0.97 – 1.13 0.237 722 7285 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1 0.881 – 1.15 0.949 238 2420 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 0.97 0.849 – 1.11 0.65 235 2364 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 1.03 0.965 – 1.09 0.405 1121 11242 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.967 0.884 – 1.06 0.472 522 5394 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 0.974 0.918 – 1.03 0.378 1239 12358 exclusion phecode
611.1 Abnormal mammogram Genitourinary 1.12 0.837 – 1.51 0.437 48 428 exclusion phecode
611.3 Lump or mass in breast Genitourinary 0.966 0.91 – 1.03 0.251 1195 11952 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1.06 0.978 – 1.15 0.161 675 7059 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1.05 0.965 – 1.14 0.268 644 6692 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 1.19 0.911 – 1.57 0.199 62 597 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.973 0.917 – 1.03 0.363 1213 13058 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 0.94 0.86 – 1.03 0.17 519 5681 exclusion phecode
613.5 Mastodynia Genitourinary 0.862 0.654 – 1.13 0.289 52 617 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 1.04 0.952 – 1.14 0.389 543 5480 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1.08 0.948 – 1.23 0.251 252 2598 exclusion phecode
613.9 Breast disorder NOS Genitourinary – 154 1613 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.972 0.943 – 1 0.0636 4555 46930 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.979 0.936 – 1.02 0.357 2029 21054 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.94 0.869 – 1.02 0.127 674 6917 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.07 0.796 – 1.43 0.662 50 511 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.943 0.844 – 1.05 0.302 335 3472 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.998 0.885 – 1.13 0.977 284 2951 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.911 0.795 – 1.04 0.182 219 2266 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.963 0.92 – 1.01 0.0995 2070 21159 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1.03 0.966 – 1.1 0.367 1039 10678 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 0.949 0.851 – 1.06 0.352 334 3428 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.914 0.842 – 0.993 0.0332 632 6251 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 0.967 0.838 – 1.12 0.643 205 2238 exclusion phecode
615 Endometriosis Genitourinary 0.969 0.935 – 1 0.0851 3310 33907 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.05 0.915 – 1.21 0.479 222 2413 exclusion phecode
618 Genital prolapse Genitourinary 1.02 1 – 1.05 0.0353 8798 89103 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 1.01 0.983 – 1.04 0.472 5502 56218 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.04 1 – 1.07 0.0287 4144 40977 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.05 0.946 – 1.17 0.353 373 3802 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1.06 0.968 – 1.17 0.198 475 5087 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1 0.979 – 1.03 0.808 6911 70025 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 0.969 0.891 – 1.05 0.469 582 5971 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 0.98 0.941 – 1.02 0.323 2576 26151 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 0.994 0.953 – 1.04 0.793 2316 23245 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.06 1.01 – 1.12 0.0316 1403 14196 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.988 0.928 – 1.05 0.713 1065 10872 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1.31 0.983 – 1.73 0.0658 51 574 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.969 0.902 – 1.04 0.385 819 8975 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.992 0.97 – 1.01 0.49 8117 82727 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.984 0.959 – 1.01 0.244 5988 62113 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 0.984 0.946 – 1.02 0.414 2767 26862 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.04 0.979 – 1.11 0.19 1009 10437 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.953 0.876 – 1.04 0.265 582 6032 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.875 0.75 – 1.02 0.0915 171 1815 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 0.978 0.871 – 1.1 0.701 320 3333 exclusion phecode
624.9 stress incontinence, female Genitourinary 1.03 1 – 1.07 0.0364 4407 45979 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.982 0.942 – 1.02 0.391 2427 24139 exclusion phecode
625.1 Dyspareunia Genitourinary 0.956 0.895 – 1.02 0.175 990 9975 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 0.989 0.971 – 1.01 0.237 13511 95319 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 0.993 0.975 – 1.01 0.504 11804 91590 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.968 0.782 – 1.2 0.767 86 937 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 0.994 0.972 – 1.02 0.625 8024 77074 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.994 0.944 – 1.05 0.814 1612 16218 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 0.991 0.956 – 1.03 0.624 3186 32196 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.988 0.936 – 1.04 0.653 1464 15245 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 1.12 0.931 – 1.35 0.226 119 1378 exclusion phecode
626.8 Infertility, female Genitourinary 0.959 0.905 – 1.02 0.153 1228 12044 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 0.978 0.955 – 1 0.0628 7565 79145 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 0.964 0.94 – 0.989 0.00458 6532 68560 exclusion phecode
627.2 Symptomatic menopause Genitourinary 1.01 0.853 – 1.21 0.871 136 1443 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1 0.932 – 1.08 0.983 797 8226 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1.09 0.953 – 1.24 0.214 241 2526 exclusion phecode
628 Ovarian cyst Genitourinary 0.971 0.94 – 1 0.0861 3823 39143 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 1.03 0.997 – 1.06 0.0802 4734 32491 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.992 0.93 – 1.06 0.807 1022 10166 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.07 0.953 – 1.21 0.247 301 2930 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.971 0.926 – 1.02 0.241 1817 15648 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.95 0.884 – 1.02 0.167 798 7773 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 1.01 0.952 – 1.07 0.729 1167 11078 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.02 0.977 – 1.07 0.349 2145 17938 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 0.95 0.871 – 1.04 0.244 563 5515 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.05 0.984 – 1.12 0.144 985 9563 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 0.933 0.728 – 1.2 0.588 61 625 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 1.02 0.952 – 1.08 0.631 981 10029 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.03 0.913 – 1.16 0.628 271 2751 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.951 0.822 – 1.1 0.501 185 1948 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 1.09 0.909 – 1.3 0.361 131 1363 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 1.01 0.946 – 1.07 0.867 1147 11281 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.999 0.955 – 1.05 0.972 2016 18854 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 1.03 0.793 – 1.35 0.801 59 600 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.13 0.997 – 1.28 0.0566 258 2476 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 1.12 0.913 – 1.38 0.273 103 1010 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.08 0.925 – 1.27 0.323 176 1744 exclusion phecode
650 Normal delivery Pregnancy Complications 0.999 0.951 – 1.05 0.953 1772 17119 exclusion phecode
651 Multiple gestation Pregnancy Complications 0.936 0.834 – 1.05 0.257 310 3126 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.971 0.923 – 1.02 0.266 1590 14954 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 0.997 0.942 – 1.06 0.92 1281 12312 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.03 0.805 – 1.31 0.823 66 656 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.992 0.959 – 1.03 0.623 3940 26537 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.07 0.867 – 1.32 0.53 95 977 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.976 0.933 – 1.02 0.305 2086 16594 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.972 0.888 – 1.06 0.538 492 4803 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 1 0.97 – 1.03 0.955 4864 26481 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 1.01 0.965 – 1.05 0.755 2333 19087 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 1.01 0.848 – 1.19 0.947 146 1472 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 0.951 0.836 – 1.08 0.443 241 2368 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 0.956 0.728 – 1.26 0.749 58 565 exclusion phecode
679 Complications of in utero procedures Dermatologic 1.17 0.883 – 1.56 0.271 48 490 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 0.999 0.967 – 1.03 0.944 4027 51507 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.923 0.829 – 1.03 0.147 353 4109 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.03 0.923 – 1.15 0.58 346 3838 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1 0.964 – 1.04 0.96 2928 38974 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1 0.965 – 1.04 0.93 2932 39017 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1 0.963 – 1.04 0.997 2904 38675 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.04 0.927 – 1.16 0.537 358 4375 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.03 0.962 – 1.11 0.364 807 9636 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.01 0.961 – 1.07 0.608 1475 17138 exclusion phecode
686.3 Pilonidal cyst Dermatologic 1.02 0.92 – 1.13 0.733 404 4550 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 1.08 0.952 – 1.23 0.226 255 2627 exclusion phecode
687 Symptoms affecting skin Dermatologic 1.05 0.94 – 1.17 0.395 351 3979 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.981 0.927 – 1.04 0.504 1288 15623 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.06 0.915 – 1.22 0.447 195 2039 exclusion phecode
687.3 Changes in skin texture Dermatologic 1.18 0.936 – 1.48 0.161 71 794 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 0.983 0.939 – 1.03 0.479 1962 21730 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.998 0.967 – 1.03 0.927 3950 41432 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.751 0.563 – 1 0.0516 46 529 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.821 0.585 – 1.15 0.253 36 386 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.727 0.576 – 0.917 0.00721 80 876 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 1 0.93 – 1.09 0.901 723 7202 exclusion phecode
694.1 Vitiligo Dermatologic 0.888 0.654 – 1.21 0.448 39 445 exclusion phecode
694.2 Other dyschromia Dermatologic 1 0.918 – 1.09 0.998 597 5704 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.16 0.907 – 1.48 0.239 68 847 exclusion phecode
695 Erythematous conditions Dermatologic 0.949 0.901 – 1 0.0491 1513 17392 exclusion phecode
695.1 Toxic erythema Dermatologic 1.1 0.852 – 1.41 0.472 66 829 exclusion phecode
695.2 Bullous dermatoses Dermatologic 0.897 0.723 – 1.11 0.321 87 966 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 1 0.717 – 1.41 0.978 36 395 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.888 0.667 – 1.18 0.418 48 516 exclusion phecode
695.3 Rosacea Dermatologic 0.906 0.79 – 1.04 0.156 224 2212 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 1.01 0.885 – 1.16 0.853 219 3148 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 1.02 0.807 – 1.29 0.87 71 955 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 1.04 0.899 – 1.21 0.579 179 2643 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 0.947 0.867 – 1.04 0.232 527 5652 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 0.841 0.712 – 0.994 0.0421 146 1752 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.826 0.63 – 1.08 0.166 55 604 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 1.01 0.893 – 1.14 0.91 280 3288 exclusion phecode
696 Psoriasis and related disorders Dermatologic 0.985 0.931 – 1.04 0.61 1320 16391 exclusion phecode
696.4 Psoriasis Dermatologic 0.982 0.927 – 1.04 0.533 1285 16044 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 0.984 0.921 – 1.05 0.638 954 12132 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 0.999 0.908 – 1.1 0.988 450 5291 exclusion phecode
697 Sarcoidosis Dermatologic 0.994 0.877 – 1.13 0.919 268 4024 exclusion phecode
698 Pruritus and related conditions Dermatologic 1.1 1.01 – 1.2 0.0369 550 5719 exclusion phecode
700 Corns and callosities Dermatologic 0.954 0.822 – 1.11 0.534 185 2154 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.01 0.972 – 1.04 0.671 3312 34327 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.913 0.698 – 1.19 0.505 54 590 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1 0.952 – 1.05 0.988 1716 17453 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 1.6 1.13 – 2.26 0.00862 38 428 exclusion phecode
701.4 Keloid scar Dermatologic 1.02 0.871 – 1.2 0.787 162 1675 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1 0.896 – 1.13 0.941 338 3396 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 0.961 0.751 – 1.23 0.755 64 767 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.988 0.956 – 1.02 0.483 3821 38063 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.974 0.927 – 1.02 0.294 1753 17669 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 1 0.959 – 1.05 0.927 2208 21594 exclusion phecode
703 Diseases of nail, NOS Dermatologic 0.974 0.854 – 1.11 0.693 230 2525 exclusion phecode
703.1 Ingrowing nail Dermatologic 1.09 1 – 1.18 0.0417 620 7152 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 1 0.97 – 1.04 0.878 3837 39206 exclusion phecode
704.1 Alopecia Dermatologic 1 0.8 – 1.26 0.983 83 992 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.02 0.78 – 1.35 0.864 58 561 exclusion phecode
705 Disorders of sweat glands Dermatologic 1 0.848 – 1.19 0.96 139 1822 exclusion phecode
705.3 Hidradenitis Dermatologic 1.02 0.842 – 1.23 0.861 114 1494 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.1 0.986 – 1.22 0.0896 361 4228 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 0.99 0.964 – 1.02 0.453 6063 61421 exclusion phecode
706.1 Acne Dermatologic 1.18 0.907 – 1.53 0.22 57 622 exclusion phecode
706.2 Sebaceous cyst Dermatologic 0.986 0.961 – 1.01 0.29 6421 64821 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.01 0.942 – 1.08 0.769 823 13259 exclusion phecode
707.1 Decubitus ulcer Dermatologic 0.943 0.856 – 1.04 0.238 426 6025 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 1.03 0.989 – 1.08 0.15 2182 24985 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.08 0.957 – 1.23 0.207 260 3817 exclusion phecode
709.3 Systemic sclerosis Dermatologic 0.93 0.757 – 1.14 0.492 90 1293 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 0.814 0.571 – 1.16 0.257 32 505 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1.02 0.974 – 1.07 0.382 1812 19648 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.992 0.883 – 1.11 0.894 290 4237 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1 0.887 – 1.13 0.989 266 3944 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 0.849 0.692 – 1.04 0.117 99 1413 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.09 0.943 – 1.26 0.244 176 2796 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 1.06 0.937 – 1.21 0.339 246 3048 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.09 0.945 – 1.27 0.229 183 2351 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.46 1.08 – 1.97 0.0127 46 569 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 0.978 0.76 – 1.26 0.859 65 1078 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 0.718 0.423 – 1.22 0.219 15 445 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.01 0.967 – 1.05 0.794 2698 35492 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.997 0.956 – 1.04 0.879 2421 32196 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 1.03 0.969 – 1.1 0.325 1023 12060 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.18 0.923 – 1.51 0.187 72 897 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 0.96 0.865 – 1.07 0.446 379 4404 exclusion phecode
716 Other arthropathies Musculoskeletal 1 0.989 – 1.02 0.712 23477 196989 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.04 0.994 – 1.09 0.0926 2074 25167 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 0.985 0.965 – 1.01 0.166 9596 111168 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1 0.988 – 1.02 0.838 22494 194363 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.01 0.928 – 1.1 0.844 598 7700 exclusion phecode
720 Spinal stenosis Musculoskeletal 1.01 0.964 – 1.05 0.749 2203 25800 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 0.994 0.965 – 1.02 0.686 4838 55921 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 0.988 0.953 – 1.03 0.523 3110 35929 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.946 0.777 – 1.15 0.579 109 1333 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 0.946 0.824 – 1.09 0.429 211 2495 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1 0.978 – 1.03 0.791 6074 66959 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 0.998 0.898 – 1.11 0.968 377 3878 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.01 0.963 – 1.06 0.669 1811 21082 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 1.06 0.8 – 1.41 0.681 47 524 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 0.987 0.95 – 1.02 0.489 2998 32921 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 0.95 0.85 – 1.06 0.364 335 3762 exclusion phecode
723.1 Torticollis Musculoskeletal 0.854 0.68 – 1.07 0.178 79 818 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.01 0.954 – 1.06 0.779 1386 15228 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1.04 0.927 – 1.17 0.48 307 3198 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 1.03 0.915 – 1.16 0.636 311 3212 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 0.892 0.644 – 1.24 0.493 39 439 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 0.995 0.935 – 1.06 0.886 1061 11786 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1.01 0.993 – 1.03 0.214 10176 107805 exclusion phecode
726.1 Enthesopathy Musculoskeletal 1.01 0.984 – 1.04 0.466 6550 69785 exclusion phecode
726.2 Synoviopathy Musculoskeletal 1.01 0.893 – 1.15 0.848 266 2591 exclusion phecode
726.3 Bursitis Musculoskeletal 1.04 0.959 – 1.14 0.315 564 6223 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.01 0.981 – 1.04 0.533 5229 54739 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 1 0.958 – 1.05 0.863 1873 20440 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 1.14 0.9 – 1.43 0.284 77 733 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.01 0.97 – 1.06 0.577 2325 23560 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 1.09 0.98 – 1.21 0.113 375 4137 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.925 0.813 – 1.05 0.239 242 2529 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.995 0.812 – 1.22 0.96 99 1022 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.969 0.93 – 1.01 0.137 2465 24188 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 0.988 0.878 – 1.11 0.838 308 3266 exclusion phecode
728.7 Fasciitis Musculoskeletal 0.971 0.933 – 1.01 0.149 2559 25266 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.968 0.928 – 1.01 0.131 2348 22728 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1 0.967 – 1.03 0.992 3620 44027 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.01 0.931 – 1.09 0.819 655 7817 exclusion phecode
729.3 Panniculitis Musculoskeletal 1.18 0.931 – 1.49 0.171 77 746 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 0.964 0.833 – 1.12 0.628 196 2119 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 0.968 0.833 – 1.12 0.667 186 2012 exclusion phecode
732 Osteochondropathies Musculoskeletal 1.04 0.932 – 1.16 0.486 344 3573 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 1.18 0.993 – 1.39 0.0609 145 1541 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 0.913 0.673 – 1.24 0.559 43 451 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 1.02 0.961 – 1.08 0.518 1196 13157 exclusion phecode
733.2 Cyst of bone Musculoskeletal 0.973 0.848 – 1.12 0.695 225 2302 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.03 0.915 – 1.15 0.669 316 3935 exclusion phecode
733.6 Costochondritis Musculoskeletal 1.15 0.922 – 1.43 0.22 85 939 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.01 0.945 – 1.09 0.686 820 9217 exclusion phecode
733.9 Chondromalacia Musculoskeletal 0.942 0.761 – 1.17 0.582 93 930 exclusion phecode
735 Acquired foot deformities Musculoskeletal 0.999 0.975 – 1.02 0.935 6982 71984 exclusion phecode
735.1 Flat foot Musculoskeletal 0.908 0.759 – 1.09 0.289 122 1423 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 1.02 0.985 – 1.06 0.272 3551 37254 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.03 0.978 – 1.09 0.24 1329 14089 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.995 0.936 – 1.06 0.869 1142 11378 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 1 0.971 – 1.03 0.98 4947 50311 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 0.977 0.917 – 1.04 0.48 1006 11671 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1 0.86 – 1.16 0.994 171 1820 exclusion phecode
737 Curvature of spine Musculoskeletal 0.977 0.904 – 1.06 0.555 691 8211 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 0.974 0.899 – 1.05 0.513 649 7702 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 1.01 0.953 – 1.07 0.746 1249 13821 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.994 0.93 – 1.06 0.864 955 10770 exclusion phecode
739 Contracture of joint Musculoskeletal 1.02 0.91 – 1.15 0.726 306 3667 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.01 0.995 – 1.03 0.201 17376 166682 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 1 0.985 – 1.02 0.625 11040 119049 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.01 0.985 – 1.04 0.377 5522 62406 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.07 0.93 – 1.23 0.355 227 2490 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 1.01 0.906 – 1.13 0.84 343 4215 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.01 0.99 – 1.04 0.263 7456 87250 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.01 0.969 – 1.05 0.622 2324 25926 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 0.873 0.682 – 1.12 0.284 68 725 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.02 0.927 – 1.12 0.677 450 4582 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 1.13 0.911 – 1.41 0.265 79 1092 exclusion phecode
741.4 Joint effusions Musculoskeletal 1.02 0.952 – 1.1 0.558 843 10050 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.16 0.909 – 1.48 0.235 68 795 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.866 0.609 – 1.23 0.422 37 413 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 0.986 0.942 – 1.03 0.526 2079 21769 exclusion phecode
742.1 Loose body in joint Musculoskeletal 1.02 0.893 – 1.16 0.792 236 2417 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.06 0.837 – 1.34 0.64 75 790 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.06 0.953 – 1.19 0.272 350 3839 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.97 0.919 – 1.02 0.257 1489 15364 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.03 1 – 1.06 0.0417 4923 54050 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1.03 0.993 – 1.06 0.128 4147 45488 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1.03 0.991 – 1.06 0.157 3611 39824 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 0.998 0.892 – 1.12 0.975 319 3471 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.07 0.947 – 1.21 0.28 281 3692 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.06 0.971 – 1.15 0.196 583 6068 exclusion phecode
745 Pain in joint Musculoskeletal 1 0.973 – 1.03 0.971 5204 58798 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.971 0.924 – 1.02 0.259 1632 19231 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.972 0.922 – 1.02 0.285 1509 17983 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.96 0.868 – 1.06 0.421 413 4430 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.952 0.812 – 1.12 0.54 152 1731 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1.01 0.942 – 1.08 0.832 929 11802 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.934 0.772 – 1.13 0.484 116 1230 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 0.962 0.69 – 1.34 0.817 35 360 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 0.95 0.832 – 1.08 0.448 226 2300 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 1.01 0.916 – 1.12 0.816 420 4857 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.04 0.9 – 1.2 0.607 206 2222 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.937 0.78 – 1.13 0.488 122 1296 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.959 0.832 – 1.11 0.565 210 2597 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.868 0.736 – 1.02 0.0916 158 1622 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 1.16 0.863 – 1.56 0.328 46 877 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.986 0.922 – 1.05 0.687 905 11418 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 1.01 0.92 – 1.1 0.91 537 5406 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.974 0.876 – 1.08 0.627 372 3782 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 1.14 0.966 – 1.34 0.122 155 1519 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 0.969 0.874 – 1.07 0.554 370 6043 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 1 0.846 – 1.19 0.979 133 3003 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 1.13 0.978 – 1.31 0.0971 186 2457 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.856 0.749 – 0.978 0.0226 231 2580 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 0.925 0.797 – 1.07 0.307 180 2025 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.942 0.797 – 1.11 0.482 145 1665 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.73 0.545 – 0.977 0.0346 54 593 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.01 0.804 – 1.27 0.935 81 953 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.09 0.811 – 1.47 0.568 47 581 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 1.14 0.904 – 1.43 0.27 72 859 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.971 0.865 – 1.09 0.615 306 3285 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.917 0.777 – 1.08 0.303 153 1554 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.963 0.801 – 1.16 0.686 114 1299 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 1.09 0.878 – 1.36 0.427 76 870 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 1.01 0.916 – 1.12 0.811 414 4400 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.867 0.671 – 1.12 0.275 60 635 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 1.06 0.945 – 1.2 0.304 297 3254 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 0.871 0.71 – 1.07 0.183 88 1308 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 0.751 0.548 – 1.03 0.0753 36 648 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.913 0.768 – 1.08 0.301 133 1586 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 0.957 0.747 – 1.23 0.725 64 704 exclusion phecode
760 Back pain Symptoms 1.01 0.983 – 1.03 0.572 7241 82599 exclusion phecode
761 Cervicalgia Symptoms 0.978 0.922 – 1.04 0.451 1226 13386 exclusion phecode
764 Sciatica Symptoms 1.03 0.977 – 1.08 0.283 1561 17542 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 0.939 0.871 – 1.01 0.0952 749 8615 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.07 0.971 – 1.19 0.166 414 4712 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 1.04 0.955 – 1.14 0.36 563 6326 exclusion phecode
771.1 Swelling of limb Symptoms 0.998 0.96 – 1.04 0.937 2688 33176 exclusion phecode
772 Symptoms of the muscles Symptoms 1.02 0.925 – 1.13 0.665 423 4807 exclusion phecode
773 Pain in limb Symptoms 1.01 0.981 – 1.05 0.42 3953 45671 exclusion phecode
780 Hypothermia/Chills Symptoms 0.853 0.693 – 1.05 0.136 97 1231 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.02 0.964 – 1.09 0.451 1200 13658 exclusion phecode
782.3 Edema Symptoms 1.05 0.975 – 1.13 0.196 745 11377 exclusion phecode
782.6 Pallor and flushing Symptoms 1.03 0.85 – 1.24 0.795 119 1247 exclusion phecode
783 Fever of unknown origin Symptoms 0.987 0.948 – 1.03 0.547 2439 28217 exclusion phecode
785 Abdominal pain Symptoms 1 0.988 – 1.01 0.99 28423 225671 exclusion phecode
788 Syncope and collapse Symptoms 0.974 0.948 – 1 0.0582 5658 63507 exclusion phecode
789 Nausea and vomiting Symptoms 1.01 0.985 – 1.03 0.471 7405 85578 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.06 0.857 – 1.32 0.58 87 1038 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 0.709 0.52 – 0.966 0.0295 38 573 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.01 0.974 – 1.04 0.68 3644 41750 exclusion phecode
791 Gangrene Symptoms 1.09 0.959 – 1.24 0.183 244 3880 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.845 0.67 – 1.07 0.157 76 727 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.06 0.848 – 1.33 0.608 85 945 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 0.983 0.883 – 1.09 0.758 349 3993 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.791 0.643 – 0.974 0.027 96 1018 exclusion phecode
797 Shock Symptoms 1.04 0.821 – 1.31 0.755 77 1011 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.1 0.817 – 1.49 0.525 46 639 exclusion phecode
798 Malaise and fatigue Symptoms 0.969 0.927 – 1.01 0.157 2176 24992 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 0.982 0.891 – 1.08 0.714 447 4590 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 0.989 0.96 – 1.02 0.451 4863 50960 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 0.953 0.898 – 1.01 0.119 1178 12464 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 0.916 0.748 – 1.12 0.398 105 1222 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.04 0.984 – 1.09 0.174 1569 16175 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 0.961 0.879 – 1.05 0.383 532 5519 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 0.977 0.927 – 1.03 0.375 1561 16475 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1 0.948 – 1.06 0.922 1313 13664 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1 0.916 – 1.1 0.932 488 5176 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 1.02 0.992 – 1.05 0.176 6088 61074 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1.04 0.979 – 1.11 0.2 1139 12241 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.01 0.981 – 1.05 0.399 3930 38861 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1 0.942 – 1.07 0.959 1111 10928 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.957 0.918 – 0.997 0.0367 2464 24889 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 0.986 0.922 – 1.05 0.685 927 9901 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 1.04 0.953 – 1.14 0.365 526 5437 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 0.975 0.91 – 1.04 0.463 887 9451 exclusion phecode
817 Concussion Injuries & Poisonings 1.06 0.913 – 1.24 0.427 180 1822 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.01 0.905 – 1.13 0.822 333 3559 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.01 0.969 – 1.06 0.558 2173 22133 exclusion phecode
823 Torus fracture Injuries & Poisonings 1.02 0.965 – 1.09 0.443 1226 12588 exclusion phecode
830 Dislocation Injuries & Poisonings 1.02 0.965 – 1.07 0.513 1519 15494 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 0.992 0.972 – 1.01 0.396 10995 112652 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 1.11 0.998 – 1.23 0.0547 366 3840 exclusion phecode
840 Sprains and strains Injuries & Poisonings 1.06 0.948 – 1.18 0.32 358 3560 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.03 0.996 – 1.07 0.0829 3428 38344 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 1.03 0.835 – 1.28 0.758 94 1115 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.08 0.952 – 1.22 0.238 276 3525 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.04 0.968 – 1.11 0.305 866 12213 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 1.02 0.947 – 1.1 0.586 734 8833 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 1.05 0.999 – 1.1 0.0537 1936 22544 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.02 0.973 – 1.07 0.433 2013 23394 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.14 0.814 – 1.59 0.452 40 530 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 0.972 0.932 – 1.01 0.19 2338 25149 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.925 0.79 – 1.08 0.33 183 1967 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 0.969 0.809 – 1.16 0.734 125 1439 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 0.964 0.92 – 1.01 0.117 1943 20767 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 0.976 0.825 – 1.15 0.773 148 1535 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.958 0.712 – 1.29 0.777 48 511 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 0.994 0.957 – 1.03 0.775 2888 29962 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.999 0.725 – 1.38 0.997 41 369 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.08 0.829 – 1.4 0.579 62 656 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 0.849 0.705 – 1.02 0.0837 118 1315 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.08 0.963 – 1.2 0.193 349 3368 exclusion phecode
873 Broken tooth Injuries & Poisonings 1.05 0.895 – 1.24 0.543 158 1673 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 0.963 0.783 – 1.18 0.717 87 1237 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.05 0.869 – 1.28 0.595 113 1185 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.03 0.962 – 1.1 0.395 910 9756 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 0.998 0.959 – 1.04 0.902 2732 30875 exclusion phecode
916 Contusion Injuries & Poisonings 1.02 0.956 – 1.09 0.526 958 10427 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 1.01 0.836 – 1.21 0.952 134 1399 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 0.92 0.808 – 1.05 0.207 250 2641 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.922 0.788 – 1.08 0.315 168 1712 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 0.978 0.925 – 1.03 0.439 1350 15276 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.09 0.924 – 1.28 0.31 152 1568 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.914 0.707 – 1.18 0.491 62 732 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.01 0.902 – 1.13 0.873 333 4070 exclusion phecode
947 Urticaria Injuries & Poisonings 1 0.88 – 1.15 0.951 249 2770 exclusion phecode
949 Allergies, other Injuries & Poisonings 0.952 0.842 – 1.08 0.44 280 3065 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.976 0.866 – 1.1 0.693 296 3088 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 1.01 0.859 – 1.19 0.905 158 1935 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 0.919 0.818 – 1.03 0.155 310 3587 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 0.804 0.561 – 1.15 0.236 30 385 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.925 0.691 – 1.24 0.597 51 506 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.01 0.995 – 1.03 0.153 12268 135935 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.01 0.99 – 1.03 0.336 10735 118729 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.04 0.919 – 1.19 0.508 253 3125 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.951 0.873 – 1.04 0.245 575 6701 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.05 0.902 – 1.21 0.555 192 2752 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.04 0.897 – 1.21 0.596 188 2693 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.911 0.77 – 1.08 0.273 148 1787 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.05 0.881 – 1.25 0.583 121 1978 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.03 0.864 – 1.24 0.724 116 1929 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.01 0.976 – 1.04 0.639 3968 45867 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 0.948 0.88 – 1.02 0.162 758 8661 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.01 0.9 – 1.12 0.922 334 3867 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.891 0.783 – 1.01 0.0773 253 2948 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 0.974 0.872 – 1.09 0.64 347 4037 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.03 0.931 – 1.14 0.576 404 4411 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.01 0.957 – 1.07 0.67 1325 15609 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 0.812 0.679 – 0.971 0.0227 121 1510 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 0.979 0.835 – 1.15 0.791 157 2049 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.919 0.698 – 1.21 0.547 51 670 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.04 0.807 – 1.33 0.781 66 835 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.04 0.763 – 1.43 0.788 35 711 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.749 0.546 – 1.03 0.0726 41 509 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.05 0.771 – 1.44 0.746 39 449 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 1 0.846 – 1.18 1 143 1740 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 1.09 0.994 – 1.2 0.0672 458 5403 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 1.04 0.881 – 1.23 0.629 136 1611 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 0.716 0.538 – 0.954 0.0225 45 460 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 0.778 0.606 – 0.999 0.0495 61 764 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.846 0.676 – 1.06 0.143 86 877 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.761 0.589 – 0.983 0.0368 53 617 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.01 0.965 – 1.06 0.667 2013 21824 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 0.981 0.932 – 1.03 0.467 1560 21063 exclusion phecode
994.2 Sepsis Injuries & Poisonings 0.981 0.932 – 1.03 0.467 1560 21063 exclusion phecode
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