Departments of Anesthesiology and Biostatistics | University of Michigan

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Scores Estimated glomerular filtration rate based on cystatin C UK Biobank (UKB) PheWAS analysis

Estimated glomerular filtration rate based on cystatin C — UK Biobank (UKB) PRS PheWAS

PRS model
PRS ID exprsweb-egfr-cystatinc-egfrcys-overall-iv-2gc-pt-ukb-20211120Legacy PTC+T (DS)Large GWAS

Evaluation cohort: UK Biobank (UKB).

This page pairs the PheWAS plot with the full sortable table for the all-subject and exclusion scans.

Read the all-subject and exclusion scans separately. The combined view is only a browsing aid, and the selected-phecode panel below is only meaningful when the same phecode exists in both scans.

ExPRS exclusion definition

Exclusion cohort: study-defined normal-range subset.

For this ExPRS, the exclusion sensitivity scan keeps only the study-defined normal-range subset for Estimated glomerular filtration rate based on cystatin C before rerunning the PheWAS. The preserved release does not include numeric bounds for this trait. This is an exposure-based sensitivity analysis rather than a diagnosis-based exclusion.

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Signal overview

The plot gives a quick view of the currently visible associations. Click a point to pin its details, inspect that phecode across scans when both rows exist, or open the matching phecode detail page.

89 rows visible 16 categories
Phecode Description Category OR 95% CI P value Cases Controls Analysis Link
008 Intestinal infection Infectious Diseases 1.01 0.985 – 1.03 0.519 8842 88430 all phecode
008.5 Bacterial enteritis Infectious Diseases 0.996 0.957 – 1.04 0.841 2718 27172 all phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.02 0.939 – 1.1 0.675 653 6533 all phecode
008.6 Viral Enteritis Infectious Diseases 1.01 0.945 – 1.08 0.736 862 8622 all phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 0.906 0.694 – 1.18 0.468 55 550 all phecode
010 Tuberculosis Infectious Diseases 0.979 0.835 – 1.15 0.799 166 1659 all phecode
038 Septicemia Infectious Diseases 1.01 0.974 – 1.04 0.72 4175 41776 all phecode
038.1 Gram negative septicemia Infectious Diseases 1.02 0.951 – 1.09 0.578 850 8501 all phecode
038.2 Gram positive septicemia Infectious Diseases 0.992 0.905 – 1.09 0.859 494 4978 all phecode
041 Bacterial infection NOS Infectious Diseases 1.01 0.991 – 1.03 0.303 12017 120377 all phecode
041.1 Staphylococcus infections Infectious Diseases 1.06 1.02 – 1.1 0.00309 3128 31348 all phecode
041.2 Streptococcus infection Infectious Diseases 0.998 0.949 – 1.05 0.949 1641 16433 all phecode
041.4 E. coli Infectious Diseases 1.03 0.99 – 1.07 0.152 2730 27319 all phecode
053 Herpes zoster Infectious Diseases 0.917 0.827 – 1.02 0.0988 411 4137 all phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.772 0.621 – 0.96 0.02 95 949 all phecode
054 Herpes simplex Infectious Diseases 1.04 0.903 – 1.19 0.597 211 2107 all phecode
070 Viral hepatitis Infectious Diseases 1 0.92 – 1.09 0.993 590 5916 all phecode
070.1 Viral hepatitis A Infectious Diseases 0.962 0.752 – 1.23 0.758 69 690 all phecode
070.2 Viral hepatitis B Infectious Diseases 1 0.845 – 1.19 0.975 132 1330 all phecode
070.3 Viral hepatitis C Infectious Diseases 1.04 0.92 – 1.18 0.51 255 2568 all phecode
070.4 Chronic hepatitis Infectious Diseases 0.942 0.83 – 1.07 0.353 276 2767 all phecode
070.9 Hepatitis NOS Infectious Diseases 0.984 0.892 – 1.09 0.751 428 4287 all phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.09 0.923 – 1.28 0.311 147 1467 all phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.05 0.874 – 1.26 0.597 117 1168 all phecode
078 Viral warts & HPV Infectious Diseases 0.988 0.926 – 1.05 0.718 1004 10036 all phecode
079 Viral infection Infectious Diseases 0.99 0.951 – 1.03 0.604 2769 27694 all phecode
079.1 Varicella infection Infectious Diseases 1.06 0.827 – 1.35 0.665 64 640 all phecode
080 Postoperative infection Infectious Diseases 1.01 0.984 – 1.05 0.341 4473 44775 all phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.03 0.989 – 1.07 0.147 2477 24765 all phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.934 0.725 – 1.2 0.597 71 709 all phecode
1000 Burns Injuries & Poisonings 0.998 0.916 – 1.09 0.968 578 5796 all phecode
1001 Foreign body injury Injuries & Poisonings 1.07 1.01 – 1.13 0.0307 1199 12007 all phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1 0.973 – 1.03 1 5480 54819 all phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.05 0.94 – 1.18 0.364 300 2997 all phecode
1005 Other symptoms Injuries & Poisonings 1.02 0.963 – 1.07 0.551 1444 14422 all phecode
1006 Crushing injury Injuries & Poisonings 0.978 0.861 – 1.11 0.735 256 2558 all phecode
1007 Injury to blood vessels Injuries & Poisonings 1.04 0.923 – 1.18 0.508 256 2559 all phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1.01 0.946 – 1.08 0.787 1013 10132 all phecode
1009 Injury, NOS Injuries & Poisonings 1.02 0.997 – 1.04 0.0952 8482 84911 all phecode
1010 Other tests Injuries & Poisonings 0.997 0.971 – 1.02 0.841 5945 59512 all phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 0.996 0.975 – 1.02 0.698 9152 91588 all phecode
1012 Late effect Injuries & Poisonings 1.03 0.843 – 1.25 0.789 105 1057 all phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.06 0.947 – 1.19 0.305 316 3168 all phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.13 0.887 – 1.44 0.326 66 659 all phecode
1015 Effects of other external causes Injuries & Poisonings 0.983 0.952 – 1.01 0.28 4226 42294 all phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.01 0.995 – 1.03 0.187 15895 159019 all phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 0.983 0.869 – 1.11 0.784 279 2810 all phecode
110.1 Dermatophytosis Infectious Diseases 0.983 0.869 – 1.11 0.792 273 2750 all phecode
110.11 Dermatophytosis of nail Infectious Diseases 1.08 0.855 – 1.37 0.511 74 756 all phecode
110.12 Althete's foot Infectious Diseases 0.91 0.767 – 1.08 0.28 141 1410 all phecode
112 Candidiasis Infectious Diseases 0.962 0.92 – 1.01 0.0927 2126 21275 all phecode
117 Mycoses Infectious Diseases 1.04 0.926 – 1.18 0.48 272 2719 all phecode
117.4 Aspergillosis Infectious Diseases 1.1 0.939 – 1.28 0.245 165 1650 all phecode
130 Spirochetal infection Infectious Diseases 0.982 0.783 – 1.23 0.874 80 800 all phecode
133 Arthropod-borne diseases Infectious Diseases 1.09 0.86 – 1.38 0.479 69 689 all phecode
134 Helminthiases Infectious Diseases 0.996 0.833 – 1.19 0.964 127 1267 all phecode
134.1 Intestinal helminthiases Infectious Diseases 0.983 0.809 – 1.19 0.864 106 1058 all phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.08 0.938 – 1.24 0.288 205 2050 all phecode
145 Cancer of mouth Neoplasms 0.999 0.921 – 1.08 0.983 642 6415 all phecode
145.2 Cancer of tongue Neoplasms 0.984 0.876 – 1.11 0.787 310 3096 all phecode
145.3 Cancer of major salivary glands Neoplasms 1.06 0.867 – 1.29 0.575 105 1049 all phecode
145.5 Cancer of the mouth floor Neoplasms 0.958 0.726 – 1.26 0.763 54 539 all phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.879 0.808 – 0.955 0.00245 635 6342 all phecode
149.1 Cancer of oropharynx Neoplasms 0.843 0.737 – 0.963 0.012 252 2517 all phecode
149.4 Cancer of larynx Neoplasms 0.903 0.794 – 1.03 0.12 265 2640 all phecode
149.9 Cancer of of nasal cavities Neoplasms 0.808 0.613 – 1.07 0.131 57 570 all phecode
150 Cancer of esophagus Neoplasms 0.906 0.84 – 0.978 0.0114 762 7630 all phecode
151 Cancer of stomach Neoplasms 0.98 0.899 – 1.07 0.653 569 5696 all phecode
153 Colorectal cancer Neoplasms 1 0.972 – 1.03 0.89 4580 45799 all phecode
153.2 Colon cancer Neoplasms 1.01 0.972 – 1.05 0.653 3105 31046 all phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.986 0.944 – 1.03 0.544 2164 21640 all phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 0.976 0.881 – 1.08 0.64 400 4008 all phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 0.979 0.834 – 1.15 0.792 158 1580 all phecode
157 Pancreatic cancer Neoplasms 0.976 0.901 – 1.06 0.55 659 6582 all phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1 0.939 – 1.07 0.999 1063 10635 all phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.979 0.952 – 1.01 0.134 5567 55694 all phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 0.991 0.856 – 1.15 0.902 190 1900 all phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.916 0.792 – 1.06 0.233 205 2048 all phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.02 0.881 – 1.18 0.798 193 1925 all phecode
164 Cancer of intrathoracic organs Neoplasms 1.11 0.86 – 1.44 0.416 60 600 all phecode
165 Cancer within the respiratory system Neoplasms 0.992 0.955 – 1.03 0.692 2824 28235 all phecode
165.1 Cancer of bronchus; lung Neoplasms 1.01 0.969 – 1.06 0.583 2230 22307 all phecode
170 Cancer of bone and connective tissue Neoplasms 1.05 0.951 – 1.16 0.329 437 4364 all phecode
170.1 Bone cancer Neoplasms 1.21 1.02 – 1.45 0.0312 131 1309 all phecode
170.2 Cancer of connective tissue Neoplasms 1.01 0.902 – 1.13 0.843 331 3303 all phecode
172 Skin cancer Neoplasms 0.99 0.973 – 1.01 0.265 13495 134987 all phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.957 0.919 – 0.996 0.031 2681 26792 all phecode
172.11 Melanomas of skin Neoplasms 0.955 0.918 – 0.994 0.0253 2713 27112 all phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.995 0.975 – 1.01 0.605 11000 110056 all phecode
172.3 Carcinoma in situ of skin Neoplasms 1.05 0.971 – 1.14 0.223 666 6656 all phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.921 0.789 – 1.07 0.296 181 1818 all phecode
174 Breast cancer Neoplasms 0.998 0.98 – 1.02 0.841 12686 126597 all phecode
174.1 Breast cancer [female] Neoplasms 0.999 0.981 – 1.02 0.909 12476 124506 all phecode
174.11 Malignant neoplasm of female breast Neoplasms 0.992 0.974 – 1.01 0.426 11757 117502 all phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 1.02 0.852 – 1.23 0.799 115 1148 all phecode
175 Acquired absence of breast Neoplasms 0.985 0.945 – 1.03 0.481 2400 24010 all phecode
180 Cervical cancer and dysplasia Neoplasms 0.961 0.919 – 1 0.079 2174 21747 all phecode
180.1 Cervical cancer Neoplasms 0.975 0.86 – 1.1 0.685 272 2720 all phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.949 0.907 – 0.994 0.026 2078 20784 all phecode
182 Malignant neoplasm of uterus Neoplasms 0.969 0.914 – 1.03 0.283 1282 12836 all phecode
184 Cancer of other female genital organs Neoplasms 1 0.949 – 1.06 0.917 1378 13772 all phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 1.01 0.947 – 1.08 0.722 967 9667 all phecode
184.11 Malignant neoplasm of ovary Neoplasms 1.01 0.948 – 1.08 0.683 939 9387 all phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.924 0.818 – 1.04 0.2 305 3049 all phecode
185 Cancer of prostate Neoplasms 1.02 0.994 – 1.05 0.132 5974 58812 all phecode
187 Cancer of other male genital organs Neoplasms 1.05 0.955 – 1.15 0.314 449 4485 all phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.25 0.985 – 1.58 0.0665 70 700 all phecode
187.2 Malignant neoplasm of testis Neoplasms 0.998 0.886 – 1.12 0.97 287 2868 all phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 1.05 0.867 – 1.26 0.639 110 1098 all phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 0.996 0.965 – 1.03 0.827 4160 41604 all phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 0.972 0.913 – 1.03 0.375 1073 10723 all phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 0.966 0.906 – 1.03 0.284 1033 10324 all phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.05 0.808 – 1.35 0.736 66 660 all phecode
189.2 Cancer of bladder Neoplasms 1.01 0.966 – 1.05 0.721 2409 24113 all phecode
189.21 Malignant neoplasm of bladder Neoplasms 1 0.958 – 1.05 0.934 2142 21447 all phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.993 0.838 – 1.18 0.939 144 1439 all phecode
190 Cancer of eye Neoplasms 0.825 0.704 – 0.968 0.018 176 1758 all phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.979 0.905 – 1.06 0.591 689 6879 all phecode
191.1 Cancer of brain and nervous system Neoplasms 1.01 0.925 – 1.1 0.856 566 5650 all phecode
191.11 Cancer of brain Neoplasms 1.01 0.925 – 1.11 0.807 525 5240 all phecode
193 Thyroid cancer Neoplasms 1.11 0.998 – 1.23 0.0554 346 3466 all phecode
194 Cancer of other endocrine glands Neoplasms 0.918 0.745 – 1.13 0.421 95 949 all phecode
195 Cancer, suspected or other Neoplasms 0.984 0.968 – 1 0.0442 16967 165463 all phecode
195.1 Malignant neoplasm, other Neoplasms 0.982 0.966 – 0.998 0.0298 16267 159497 all phecode
197 Chemotherapy Neoplasms 1 0.988 – 1.02 0.819 21433 213213 all phecode
198 Secondary malignant neoplasm Neoplasms 0.994 0.974 – 1.02 0.605 9552 95503 all phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1 0.973 – 1.03 0.953 5368 53670 all phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.974 0.933 – 1.02 0.235 2267 22670 all phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 0.99 0.94 – 1.04 0.719 1549 15496 all phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 0.998 0.959 – 1.04 0.93 2665 26648 all phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.948 0.883 – 1.02 0.148 848 8473 all phecode
198.6 Secondary malignancy of bone Neoplasms 1.02 0.978 – 1.07 0.329 2161 21600 all phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.878 0.753 – 1.02 0.0967 188 1890 all phecode
199 Neoplasm of uncertain behavior Neoplasms 0.973 0.921 – 1.03 0.321 1432 14313 all phecode
199.4 Neurofibromatosis Neoplasms 0.867 0.698 – 1.08 0.196 95 950 all phecode
200 Myeloproliferative disease Neoplasms 1.04 0.972 – 1.11 0.27 991 9911 all phecode
200.1 Polycythemia vera Neoplasms 1.09 0.982 – 1.21 0.106 387 3867 all phecode
201 Hodgkin's disease Neoplasms 0.969 0.852 – 1.1 0.634 259 2598 all phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 0.996 0.954 – 1.04 0.841 2264 22709 all phecode
202.2 Non-Hodgkins lymphoma Neoplasms 0.994 0.947 – 1.04 0.813 1802 18073 all phecode
202.21 Nodular lymphoma Neoplasms 1.17 1.05 – 1.3 0.00379 363 3647 all phecode
202.24 Large cell lymphoma Neoplasms 1.01 0.93 – 1.1 0.796 581 5824 all phecode
204 Leukemia Neoplasms 0.961 0.913 – 1.01 0.125 1660 16630 all phecode
204.1 Lymphoid leukemia Neoplasms 0.921 0.844 – 1 0.0645 577 5784 all phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.03 0.77 – 1.36 0.866 56 560 all phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.912 0.832 – 1 0.0527 507 5084 all phecode
204.2 Myeloid leukemia Neoplasms 0.983 0.893 – 1.08 0.73 462 4617 all phecode
204.21 Myeloid leukemia, acute Neoplasms 0.987 0.882 – 1.1 0.817 329 3287 all phecode
204.22 Myeloid leukemia, chronic Neoplasms 1 0.843 – 1.19 0.998 144 1440 all phecode
204.4 Multiple myeloma Neoplasms 0.958 0.877 – 1.05 0.338 555 5560 all phecode
208 Benign neoplasm of colon Neoplasms 0.997 0.982 – 1.01 0.649 19856 191891 all phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 0.974 0.912 – 1.04 0.426 978 9781 all phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.04 1.01 – 1.07 0.00272 5243 52452 all phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.982 0.878 – 1.1 0.749 347 3466 all phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.1 0.976 – 1.23 0.12 318 3187 all phecode
214 Lipoma Neoplasms 1.01 0.983 – 1.04 0.487 6231 62346 all phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.02 0.986 – 1.05 0.301 4585 45872 all phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.06 0.996 – 1.12 0.0685 1107 11061 all phecode
216 Benign neoplasm of skin Neoplasms 1.01 0.988 – 1.04 0.329 7664 76660 all phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.03 0.953 – 1.12 0.433 632 6313 all phecode
217.1 Nevus, non-neoplastic Neoplasms 1.03 0.947 – 1.12 0.51 595 5943 all phecode
218 Benign neoplasm of uterus Neoplasms 1 0.981 – 1.02 0.909 10023 100200 all phecode
218.1 Uterine leiomyoma Neoplasms 1 0.98 – 1.02 0.979 10241 102376 all phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.977 0.877 – 1.09 0.674 355 3548 all phecode
220 Benign neoplasm of ovary Neoplasms 0.992 0.939 – 1.05 0.76 1445 14483 all phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.87 0.755 – 1 0.0553 220 2196 all phecode
222 Benign neoplasm of male genital organs Neoplasms 1.13 0.97 – 1.32 0.116 160 1600 all phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.11 0.952 – 1.29 0.185 173 1729 all phecode
224 Benign neoplasm of eye Neoplasms 1.07 0.897 – 1.27 0.463 129 1299 all phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.13 0.891 – 1.43 0.316 67 680 all phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.934 0.868 – 1.01 0.0706 816 8155 all phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.945 0.876 – 1.02 0.137 775 7756 all phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.778 0.581 – 1.04 0.0916 59 589 all phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.892 0.784 – 1.01 0.0812 266 2664 all phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.04 0.968 – 1.11 0.295 861 8635 all phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.05 0.907 – 1.22 0.508 186 1857 all phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.1 0.995 – 1.23 0.0609 371 3709 all phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 0.988 0.879 – 1.11 0.839 309 3114 all phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.985 0.936 – 1.04 0.572 1596 15966 all phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.04 0.999 – 1.09 0.0535 2397 23955 all phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.02 0.938 – 1.11 0.648 600 6016 all phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.964 0.906 – 1.03 0.251 1107 11092 all phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.01 0.92 – 1.11 0.81 471 4706 all phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.935 0.863 – 1.01 0.0988 676 6784 all phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.02 0.974 – 1.07 0.392 1854 18531 all phecode
242.1 Graves' disease Endocrine/metabolic 0.992 0.902 – 1.09 0.876 456 4553 all phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 0.903 0.732 – 1.11 0.341 91 910 all phecode
242.3 Exophthalmos Endocrine/metabolic 1.04 0.872 – 1.23 0.678 138 1379 all phecode
244 Hypothyroidism Endocrine/metabolic 1.01 0.995 – 1.03 0.161 14590 145053 all phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.04 0.983 – 1.11 0.163 1108 11079 all phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 0.889 0.713 – 1.11 0.297 101 1010 all phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.01 0.99 – 1.03 0.412 13918 138926 all phecode
245 Thyroiditis Endocrine/metabolic 0.895 0.791 – 1.01 0.0777 288 2877 all phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.895 0.777 – 1.03 0.125 218 2177 all phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.924 0.801 – 1.07 0.276 210 2097 all phecode
246 Other disorders of thyroid Endocrine/metabolic 1.02 0.916 – 1.13 0.755 397 3975 all phecode
250 Diabetes mellitus Endocrine/metabolic 0.995 0.981 – 1.01 0.516 19787 186006 all phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.977 0.94 – 1.02 0.25 2758 27621 all phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.883 0.772 – 1.01 0.0669 239 2389 all phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 0.928 0.745 – 1.16 0.51 76 770 all phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 0.999 0.911 – 1.1 0.982 473 4744 all phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 0.98 0.839 – 1.14 0.796 160 1610 all phecode
250.2 Type 2 diabetes Endocrine/metabolic 0.994 0.979 – 1.01 0.448 17831 170202 all phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.1 0.905 – 1.35 0.328 104 1050 all phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.15 1 – 1.32 0.0428 200 2018 all phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.01 0.947 – 1.08 0.754 986 9907 all phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.02 0.927 – 1.11 0.738 503 5066 all phecode
250.4 Abnormal glucose Endocrine/metabolic 0.944 0.871 – 1.02 0.155 680 6827 all phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.967 0.852 – 1.1 0.603 265 2659 all phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.946 0.854 – 1.05 0.282 416 4178 all phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.949 0.787 – 1.15 0.587 131 1308 all phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 1.04 0.936 – 1.16 0.462 349 3495 all phecode
250.7 Diabetic retinopathy Endocrine/metabolic 0.997 0.943 – 1.05 0.925 1329 13335 all phecode
251.1 Hypoglycemia Endocrine/metabolic 0.936 0.875 – 1 0.0544 932 9370 all phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.06 0.985 – 1.13 0.123 873 8719 all phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.04 0.962 – 1.11 0.349 781 7802 all phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.2 1.02 – 1.41 0.0324 142 1418 all phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1 0.926 – 1.08 0.953 681 6821 all phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.03 0.888 – 1.19 0.699 187 1867 all phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.14 0.931 – 1.38 0.21 95 949 all phecode
253.2 Pituitary hypofunction Endocrine/metabolic 0.946 0.832 – 1.08 0.397 260 2618 all phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.779 0.624 – 0.974 0.0281 92 919 all phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.08 0.924 – 1.26 0.331 158 1578 all phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.979 0.902 – 1.06 0.621 638 6374 all phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1 0.862 – 1.17 0.962 180 1797 all phecode
255.11 Cushing's syndrome Endocrine/metabolic 0.88 0.714 – 1.08 0.231 103 1029 all phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.17 0.929 – 1.48 0.181 76 759 all phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.05 0.938 – 1.17 0.417 362 3617 all phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.05 0.937 – 1.17 0.426 361 3607 all phecode
256 Ovarian dysfunction Endocrine/metabolic 0.959 0.839 – 1.1 0.538 240 2397 all phecode
256.4 Polycystic ovaries Endocrine/metabolic 0.953 0.825 – 1.1 0.509 209 2088 all phecode
257 Testicular dysfunction Endocrine/metabolic 1.13 0.965 – 1.32 0.13 160 1619 all phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.13 0.964 – 1.33 0.128 152 1539 all phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 0.938 0.769 – 1.14 0.528 102 1020 all phecode
259 Other endocrine disorders Endocrine/metabolic 1.09 0.926 – 1.29 0.293 149 1498 all phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.961 0.833 – 1.11 0.579 202 2018 all phecode
260.1 Cachexia Endocrine/metabolic 1 0.746 – 1.35 0.99 51 510 all phecode
260.6 Anorexia Endocrine/metabolic 0.989 0.921 – 1.06 0.751 830 8317 all phecode
261 Vitamin deficiency Endocrine/metabolic 1 0.947 – 1.07 0.877 1199 11974 all phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1 0.93 – 1.08 0.942 755 7541 all phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.04 0.947 – 1.15 0.39 447 4462 all phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 0.996 0.793 – 1.25 0.974 77 769 all phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.06 0.931 – 1.2 0.384 241 2407 all phecode
269 Proteinuria Endocrine/metabolic 1.13 1.01 – 1.26 0.0317 338 3378 all phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 0.965 0.86 – 1.08 0.541 303 3028 all phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 0.973 0.86 – 1.1 0.669 261 2608 all phecode
270.32 Paraproteinemia Endocrine/metabolic 0.961 0.831 – 1.11 0.587 191 1910 all phecode
270.33 Amyloidosis Endocrine/metabolic 0.926 0.766 – 1.12 0.43 113 1129 all phecode
270.35 Macroglobulinemia Endocrine/metabolic 0.916 0.717 – 1.17 0.482 69 689 all phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.09 0.93 – 1.29 0.278 160 1600 all phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.06 0.89 – 1.26 0.518 139 1391 all phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 0.997 0.986 – 1.01 0.605 34835 235433 all phecode
272.1 Hyperlipidemia Endocrine/metabolic 0.997 0.986 – 1.01 0.591 34764 235203 all phecode
272.11 Hypercholesterolemia Endocrine/metabolic 0.998 0.987 – 1.01 0.799 32324 228083 all phecode
272.12 Hyperglyceridemia Endocrine/metabolic 1.05 0.806 – 1.38 0.707 58 580 all phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.06 0.904 – 1.24 0.477 164 1637 all phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.04 0.908 – 1.2 0.54 211 2109 all phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.02 0.99 – 1.06 0.173 3724 37231 all phecode
274.1 Gout Endocrine/metabolic 1.01 0.976 – 1.05 0.505 3171 31705 all phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.11 0.912 – 1.34 0.308 112 1119 all phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.07 0.984 – 1.16 0.114 613 6124 all phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.08 0.989 – 1.18 0.0891 558 5576 all phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.04 0.994 – 1.09 0.0863 2107 21070 all phecode
275.1 Disorders of iron metabolism Hematopoietic 1.04 0.96 – 1.13 0.339 653 6535 all phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.07 0.961 – 1.18 0.224 375 3745 all phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.04 0.984 – 1.11 0.154 1202 12019 all phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.07 0.911 – 1.26 0.414 171 1717 all phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.01 0.989 – 1.04 0.285 7284 72932 all phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.03 0.996 – 1.06 0.0822 4086 40930 all phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.08 0.945 – 1.23 0.267 239 2409 all phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1 0.954 – 1.05 0.965 1818 18200 all phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.01 0.941 – 1.07 0.862 969 9728 all phecode
276.14 Hypopotassemia Endocrine/metabolic 1.07 1.02 – 1.13 0.0104 1424 14235 all phecode
276.4 Acid-base balance disorder Endocrine/metabolic 0.986 0.928 – 1.05 0.652 1161 11629 all phecode
276.41 Acidosis Endocrine/metabolic 1 0.939 – 1.07 0.977 1056 10577 all phecode
276.42 Alkalosis Endocrine/metabolic 0.9 0.733 – 1.1 0.314 113 1129 all phecode
276.5 Hypovolemia Endocrine/metabolic 0.992 0.955 – 1.03 0.685 2827 28265 all phecode
276.6 Fluid overload Endocrine/metabolic 1.05 0.952 – 1.15 0.343 451 4535 all phecode
276.8 Polydipsia Endocrine/metabolic 0.962 0.804 – 1.15 0.672 128 1278 all phecode
277 Other disorders of metabolism Endocrine/metabolic 1 0.938 – 1.08 0.9 899 8977 all phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.99 0.89 – 1.1 0.845 362 3613 all phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.03 0.903 – 1.18 0.649 230 2298 all phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.01 0.756 – 1.34 0.963 52 520 all phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.02 1 – 1.04 0.0398 10804 108289 all phecode
278.1 Obesity Endocrine/metabolic 1.02 1 – 1.04 0.024 10642 106670 all phecode
278.3 Localized adiposity Endocrine/metabolic 0.928 0.746 – 1.15 0.501 84 838 all phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.11 0.864 – 1.42 0.424 66 660 all phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.11 0.979 – 1.26 0.102 250 2510 all phecode
279.1 Immunity deficiency Endocrine/metabolic 1.15 1 – 1.32 0.0503 209 2100 all phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.28 1.08 – 1.51 0.00517 138 1390 all phecode
279.7 Other immunological findings Endocrine/metabolic 1 0.878 – 1.15 0.959 248 2478 all phecode
280 Iron deficiency anemias Hematopoietic 1 0.978 – 1.03 0.894 7610 76168 all phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 0.999 0.976 – 1.02 0.955 7311 73153 all phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.06 0.963 – 1.17 0.237 452 4541 all phecode
281 Other deficiency anemia Hematopoietic 1.05 0.984 – 1.11 0.146 1112 11126 all phecode
281.1 Megaloblastic anemia Hematopoietic 1.04 0.976 – 1.11 0.236 1066 10669 all phecode
281.11 Pernicious anemia Hematopoietic 1.03 0.954 – 1.11 0.474 750 7514 all phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.08 0.923 – 1.25 0.352 177 1769 all phecode
281.13 Folate-deficiency anemia Hematopoietic 1.1 0.944 – 1.27 0.232 183 1836 all phecode
281.9 Deficiency anemias Hematopoietic 1.28 0.981 – 1.68 0.069 54 538 all phecode
282 Hereditary hemolytic anemias Hematopoietic 1.07 0.909 – 1.25 0.434 150 1499 all phecode
282.8 Other hemoglobinopathies Hematopoietic 0.947 0.724 – 1.24 0.691 56 560 all phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.16 0.934 – 1.43 0.184 85 849 all phecode
283 Acquired hemolytic anemias Hematopoietic 1.06 0.893 – 1.26 0.498 135 1377 all phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.957 0.782 – 1.17 0.67 103 1059 all phecode
284 Aplastic anemia Hematopoietic 1.04 0.947 – 1.15 0.39 435 4357 all phecode
285 Other anemias Hematopoietic 1.01 0.988 – 1.03 0.468 12104 121094 all phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.96 0.846 – 1.09 0.525 271 2707 all phecode
285.2 Anemia of chronic disease Hematopoietic 1.02 0.943 – 1.1 0.64 697 6980 all phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.03 0.93 – 1.13 0.597 414 4147 all phecode
286 Coagulation defects Hematopoietic 0.979 0.915 – 1.05 0.545 921 9218 all phecode
286.1 Congenital coagulation defects Hematopoietic 0.962 0.872 – 1.06 0.435 459 4594 all phecode
286.11 Von willebrand's disease Hematopoietic 0.944 0.764 – 1.17 0.592 96 959 all phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.943 0.834 – 1.07 0.348 294 2944 all phecode
286.13 Congenital factor VIII disorder Hematopoietic 0.98 0.769 – 1.25 0.871 63 630 all phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.01 0.817 – 1.26 0.902 86 860 all phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1 0.902 – 1.11 0.992 386 3867 all phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.02 0.972 – 1.08 0.384 1652 16532 all phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.05 0.882 – 1.26 0.566 129 1290 all phecode
287.2 Allergic purpura Hematopoietic 1.21 0.928 – 1.57 0.16 51 510 all phecode
287.3 Thrombocytopenia Hematopoietic 1 0.951 – 1.06 0.936 1553 15543 all phecode
287.31 Primary thrombocytopenia Hematopoietic 0.919 0.83 – 1.02 0.103 419 4195 all phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.781 0.603 – 1.01 0.0616 75 749 all phecode
288 Diseases of white blood cells Hematopoietic 0.988 0.955 – 1.02 0.476 3765 37672 all phecode
288.1 Decreased white blood cell count Hematopoietic 0.976 0.941 – 1.01 0.192 3168 31704 all phecode
288.11 Neutropenia Hematopoietic 0.976 0.94 – 1.01 0.187 3176 31784 all phecode
288.3 Eosinophilia Hematopoietic 1.15 0.914 – 1.45 0.23 71 709 all phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1 0.932 – 1.07 0.991 862 8625 all phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.924 0.819 – 1.04 0.204 290 2897 all phecode
289.4 Lymphadenitis Hematopoietic 1.02 0.98 – 1.06 0.337 2602 26061 all phecode
289.5 Diseases of spleen Hematopoietic 0.956 0.873 – 1.05 0.334 516 5153 all phecode
289.8 Polycythemia, secondary Hematopoietic 1.03 0.917 – 1.16 0.603 292 2917 all phecode
289.9 Abnormality of red blood cells Hematopoietic 1.11 0.907 – 1.37 0.302 90 900 all phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.99 0.945 – 1.04 0.669 1929 19281 all phecode
290.1 Dementias Mental Disorders 0.987 0.925 – 1.05 0.687 1004 10032 all phecode
290.11 Alzheimer's disease Mental Disorders 0.993 0.899 – 1.1 0.889 431 4307 all phecode
290.16 Vascular dementia Mental Disorders 0.966 0.836 – 1.11 0.632 201 2008 all phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.941 0.867 – 1.02 0.149 650 6501 all phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.16 0.925 – 1.45 0.2 70 709 all phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.943 0.878 – 1.01 0.109 836 8385 all phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 0.975 0.813 – 1.17 0.784 132 1320 all phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.899 0.795 – 1.02 0.0889 286 2867 all phecode
291.8 Alteration of consciousness Mental Disorders 1 0.91 – 1.11 0.94 436 4376 all phecode
292 Neurological disorders Mental Disorders 1.03 0.998 – 1.06 0.0692 4621 46260 all phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.03 0.973 – 1.08 0.345 1504 15074 all phecode
292.2 Mild cognitive impairment Mental Disorders 0.964 0.832 – 1.12 0.629 190 1907 all phecode
292.3 Memory loss Mental Disorders 1.02 0.939 – 1.1 0.706 696 6978 all phecode
292.4 Altered mental status Mental Disorders 1.03 0.988 – 1.08 0.157 2181 21827 all phecode
292.6 Hallucinations Mental Disorders 1 0.892 – 1.13 0.96 307 3073 all phecode
293 Symptoms involving head and neck Mental Disorders 1.04 0.99 – 1.08 0.129 2078 20779 all phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.974 0.909 – 1.04 0.444 901 9010 all phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.936 0.871 – 1.01 0.0761 841 8446 all phecode
295.1 Schizophrenia Mental Disorders 0.957 0.877 – 1.04 0.315 574 5766 all phecode
295.2 Paranoid disorders Mental Disorders 0.938 0.802 – 1.1 0.422 178 1780 all phecode
295.3 Psychosis Mental Disorders 0.809 0.685 – 0.954 0.012 169 1710 all phecode
296 Mood disorders Mental Disorders 1.04 1.02 – 1.05 0.000186 12372 123822 all phecode
296.1 Bipolar Mental Disorders 1.03 0.963 – 1.09 0.428 1059 10599 all phecode
296.2 Depression Mental Disorders 1.04 1.02 – 1.06 0.00023 11737 117469 all phecode
296.22 Major depressive disorder Mental Disorders 1.04 0.931 – 1.16 0.501 361 3604 all phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.942 0.839 – 1.06 0.317 311 3070 all phecode
300 Anxiety disorders Mental Disorders 1.01 0.983 – 1.03 0.539 6844 68484 all phecode
300.1 Anxiety disorder Mental Disorders 1.01 0.98 – 1.03 0.675 6324 63282 all phecode
300.11 Generalized anxiety disorder Mental Disorders 1.05 0.895 – 1.24 0.526 149 1499 all phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1 0.927 – 1.08 0.966 707 7065 all phecode
300.13 Phobia Mental Disorders 0.995 0.907 – 1.09 0.908 501 5013 all phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.901 0.756 – 1.07 0.239 140 1407 all phecode
300.4 Dysthymic disorder Mental Disorders 1.14 0.874 – 1.49 0.334 53 530 all phecode
300.8 Acute reaction to stress Mental Disorders 0.961 0.797 – 1.16 0.672 124 1238 all phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.05 0.868 – 1.27 0.611 113 1129 all phecode
301 Personality disorders Mental Disorders 1.17 1.05 – 1.31 0.00415 334 3338 all phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.13 0.936 – 1.36 0.207 119 1186 all phecode
302 Sexual and gender identity disorders Mental Disorders 1.05 0.927 – 1.19 0.451 283 2845 all phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.02 0.932 – 1.13 0.617 467 4679 all phecode
303.3 Psychogenic disorder Mental Disorders 0.964 0.862 – 1.08 0.524 350 3510 all phecode
303.4 Somatoform disorder Mental Disorders 1.08 0.902 – 1.29 0.41 123 1229 all phecode
304 Adjustment reaction Mental Disorders 1.02 0.902 – 1.14 0.792 293 2936 all phecode
305.2 Eating disorder Mental Disorders 0.941 0.758 – 1.17 0.579 90 900 all phecode
306 Other mental disorder Mental Disorders 1.01 0.993 – 1.02 0.399 28056 230087 all phecode
306.9 Tension headache Mental Disorders 1 0.89 – 1.12 0.995 315 3148 all phecode
313 Pervasive developmental disorders Mental Disorders 0.918 0.733 – 1.15 0.459 76 770 all phecode
313.3 Autism Mental Disorders 1.14 0.879 – 1.48 0.323 53 539 all phecode
315 Develomental delays and disorders Mental Disorders 0.994 0.891 – 1.11 0.907 351 3517 all phecode
315.1 Learning disorder Mental Disorders 0.931 0.788 – 1.1 0.398 161 1610 all phecode
315.2 Speech and language disorder Mental Disorders 0.946 0.765 – 1.17 0.613 88 880 all phecode
316 Substance addiction and disorders Mental Disorders 1.01 0.982 – 1.04 0.507 5313 53131 all phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.812 0.617 – 1.07 0.139 60 599 all phecode
317 Alcohol-related disorders Mental Disorders 1 0.985 – 1.02 0.719 12696 126892 all phecode
317.1 Alcoholism Mental Disorders 1 0.981 – 1.02 0.838 8890 88923 all phecode
317.11 Alcoholic liver damage Mental Disorders 0.977 0.91 – 1.05 0.516 838 8392 all phecode
318 Tobacco use disorder Mental Disorders 0.993 0.979 – 1.01 0.363 19359 185465 all phecode
320 Meningitis Neurological 0.969 0.878 – 1.07 0.529 444 4447 all phecode
323 Encephalitis Neurological 1.06 0.947 – 1.18 0.327 342 3422 all phecode
323.2 Acute (transverse) myelitis Neurological 1.18 0.942 – 1.47 0.152 74 739 all phecode
324 Other CNS infection and poliomyelitis Neurological 1.1 0.981 – 1.24 0.101 292 2916 all phecode
327 Sleep disorders Neurological 1.08 1.01 – 1.14 0.015 1164 11659 all phecode
327.3 Sleep apnea Neurological 1.01 0.982 – 1.04 0.414 4428 44318 all phecode
327.4 Insomnia Neurological 0.958 0.817 – 1.12 0.592 163 1660 all phecode
327.41 Organic or persistent insomnia Neurological 0.985 0.829 – 1.17 0.868 136 1390 all phecode
331 Other cerebral degenerations Neurological 1 0.942 – 1.06 0.956 1142 11416 all phecode
331.1 Hydrocephalus Neurological 1 0.915 – 1.1 0.938 502 5014 all phecode
331.9 Cerebral degeneration, unspecified Neurological 1.04 0.942 – 1.15 0.445 430 4298 all phecode
332 Parkinson's disease Neurological 1.06 0.996 – 1.13 0.0651 1126 11254 all phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.07 0.995 – 1.14 0.0672 894 8954 all phecode
333.1 Essential tremor Neurological 1.12 0.976 – 1.28 0.107 216 2157 all phecode
333.2 Myoclonus Neurological 1.17 0.951 – 1.45 0.136 96 958 all phecode
333.4 Torsion dystonia Neurological 0.933 0.817 – 1.07 0.308 253 2528 all phecode
334 Degenerative disease of the spinal cord Neurological 1.01 0.966 – 1.06 0.571 1812 18130 all phecode
334.1 Spinocerebellar disease Neurological 1.16 0.966 – 1.4 0.112 117 1169 all phecode
334.2 Anterior horn cell disease Neurological 1.1 0.967 – 1.25 0.149 245 2446 all phecode
335 Multiple sclerosis Neurological 1.02 0.96 – 1.07 0.603 1340 13385 all phecode
337 Disorders of the autonomic nervous system Neurological 0.998 0.88 – 1.13 0.97 266 2668 all phecode
337.1 Peripheral autonomic neuropathy Neurological 0.916 0.724 – 1.16 0.464 72 719 all phecode
338 Pain Neurological 1.08 1.01 – 1.17 0.03 768 7692 all phecode
338.1 Acute pain Neurological 1.08 0.972 – 1.19 0.155 394 3937 all phecode
338.2 Chronic pain Neurological 1.06 0.958 – 1.18 0.253 380 3817 all phecode
339 Other headache syndromes Neurological 1 0.978 – 1.02 0.966 7819 78241 all phecode
340 Migraine Neurological 0.991 0.953 – 1.03 0.638 2860 28602 all phecode
340.1 Migrain with aura Neurological 0.956 0.829 – 1.1 0.539 212 2117 all phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.03 0.905 – 1.18 0.646 252 2535 all phecode
342 Hemiplegia Neurological 1.02 0.965 – 1.07 0.519 1494 14947 all phecode
343 Infantile cerebral palsy Neurological 0.812 0.68 – 0.97 0.0217 145 1450 all phecode
344 Other paralytic syndromes Neurological 1.02 0.942 – 1.1 0.632 658 6593 all phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1.01 0.986 – 1.04 0.317 5023 50270 all phecode
345.1 Epilepsy Neurological 1.03 0.964 – 1.11 0.353 866 8661 all phecode
345.11 Generalized convulsive epilepsy Neurological 1.08 0.98 – 1.19 0.121 439 4385 all phecode
345.12 Partial epilepsy Neurological 1.04 0.925 – 1.18 0.488 277 2776 all phecode
345.3 Convulsions Neurological 1 0.958 – 1.04 0.989 2235 22339 all phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.05 0.896 – 1.24 0.526 144 1438 all phecode
348 Other conditions of brain Neurological 0.993 0.922 – 1.07 0.853 778 7808 all phecode
348.2 Cerebral edema and compression of brain Neurological 0.967 0.852 – 1.1 0.599 268 2678 all phecode
348.4 Cerebral cysts Neurological 1.11 0.938 – 1.32 0.22 133 1350 all phecode
348.7 Coma Neurological 0.942 0.844 – 1.05 0.294 358 3596 all phecode
348.8 Encephalopathy, not elsewhere classified Neurological 0.988 0.865 – 1.13 0.855 249 2504 all phecode
348.9 Other conditions of brain, NOS Neurological 1.01 0.91 – 1.12 0.85 390 3899 all phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 1.02 0.916 – 1.14 0.705 342 3414 all phecode
350 Abnormal movement Neurological 1.03 0.988 – 1.07 0.172 2671 26722 all phecode
350.1 Abnormal involuntary movements Neurological 1.02 0.95 – 1.09 0.617 887 8852 all phecode
350.2 Abnormality of gait Neurological 1.03 0.977 – 1.08 0.278 1596 15969 all phecode
350.3 Lack of coordination Neurological 1.05 0.95 – 1.17 0.318 363 3638 all phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.886 0.677 – 1.16 0.38 54 540 all phecode
351 Other peripheral nerve disorders Neurological 0.998 0.98 – 1.02 0.834 12420 124321 all phecode
352 Disorders of other cranial nerves Neurological 1.02 0.966 – 1.08 0.463 1370 13706 all phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.964 0.877 – 1.06 0.445 463 4638 all phecode
352.2 Facial nerve disorders [CN7] Neurological 1.03 0.962 – 1.1 0.396 880 8795 all phecode
353 Nerve root and plexus disorders Neurological 0.986 0.927 – 1.05 0.654 1131 11319 all phecode
353.1 Nerve plexus lesions Neurological 0.851 0.699 – 1.04 0.111 114 1138 all phecode
353.2 Nerve root lesions Neurological 1.04 0.806 – 1.35 0.742 57 570 all phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.03 0.877 – 1.22 0.692 152 1520 all phecode
357 Inflammatory and toxic neuropathy Neurological 1.04 0.989 – 1.1 0.12 1361 13648 all phecode
358 Myoneural disorders Neurological 0.99 0.862 – 1.14 0.885 211 2109 all phecode
358.1 Myasthenia gravis Neurological 1.06 0.916 – 1.22 0.455 192 1919 all phecode
359 Muscular dystrophies and other myopathies Neurological 1.02 0.926 – 1.12 0.71 465 4646 all phecode
359.1 Muscular dystrophies Neurological 0.905 0.751 – 1.09 0.291 122 1219 all phecode
359.2 Myopathy Neurological 1.06 0.949 – 1.18 0.314 360 3597 all phecode
360 Disorders of the globe Sense Organs 0.985 0.881 – 1.1 0.796 337 3367 all phecode
360.2 Progressive myopia Sense Organs 1 0.883 – 1.14 0.955 251 2508 all phecode
361 Retinal detachments and defects Sense Organs 1 0.967 – 1.04 0.888 3246 32453 all phecode
361.1 Retinal detachment with retinal defect Sense Organs 1 0.95 – 1.06 0.884 1389 13884 all phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.994 0.775 – 1.27 0.96 68 680 all phecode
362 Other retinal disorders Sense Organs 1.01 0.976 – 1.04 0.618 3836 38370 all phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.02 0.972 – 1.06 0.493 2182 21813 all phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.01 0.971 – 1.06 0.508 2179 21783 all phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.04 0.888 – 1.21 0.642 161 1609 all phecode
362.31 Separation of retinal layers Sense Organs 1.14 0.936 – 1.38 0.196 99 990 all phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.04 0.967 – 1.11 0.304 848 8477 all phecode
362.6 Peripheral retinal degenerations Sense Organs 0.943 0.811 – 1.1 0.446 182 1827 all phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.934 0.745 – 1.17 0.554 82 812 all phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.992 0.824 – 1.19 0.931 116 1159 all phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.972 0.829 – 1.14 0.731 170 1699 all phecode
363.3 Chorioretinal scars Sense Organs 0.959 0.753 – 1.22 0.732 69 690 all phecode
364 Corneal opacity and other disorders of cornea Sense Organs 1.01 0.931 – 1.09 0.831 647 6485 all phecode
364.1 Corneal opacity Sense Organs 1.1 0.894 – 1.36 0.362 90 910 all phecode
364.2 Corneal edema Sense Organs 0.892 0.702 – 1.13 0.347 79 800 all phecode
364.4 Corneal degenerations Sense Organs 1.13 0.978 – 1.3 0.0968 201 2017 all phecode
364.41 Keratoconus Sense Organs 1.1 0.893 – 1.37 0.358 86 869 all phecode
364.5 Corneal dystrophy Sense Organs 0.94 0.816 – 1.08 0.398 211 2109 all phecode
364.9 Cornea replaced by transplant Sense Organs 0.817 0.663 – 1.01 0.0565 100 1000 all phecode
365 Glaucoma Sense Organs 1 0.972 – 1.03 0.895 4408 44136 all phecode
365.1 Open-angle glaucoma Sense Organs 1.03 0.967 – 1.1 0.355 1032 10346 all phecode
365.11 Primary open angle glaucoma Sense Organs 1.03 0.969 – 1.1 0.322 1026 10287 all phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.02 0.948 – 1.11 0.542 698 6996 all phecode
366 Cataract Sense Organs 1 0.987 – 1.02 0.805 19926 168711 all phecode
366.1 Nonsenile Cataract Sense Organs 1.02 0.802 – 1.31 0.845 69 700 all phecode
366.2 Senile cataract Sense Organs 0.996 0.973 – 1.02 0.704 8231 81909 all phecode
366.3 Traumatic cataract Sense Organs 1.09 0.892 – 1.33 0.407 102 1019 all phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.998 0.957 – 1.04 0.941 2408 24092 all phecode
367.1 Myopia Sense Organs 1.03 0.971 – 1.09 0.332 1251 12519 all phecode
367.2 Astigmatism Sense Organs 0.937 0.803 – 1.09 0.412 190 1899 all phecode
367.8 Hypermetropia Sense Organs 1.03 0.904 – 1.17 0.665 253 2530 all phecode
367.9 Blindness and low vision Sense Organs 0.966 0.895 – 1.04 0.374 719 7198 all phecode
368 Visual disturbances Sense Organs 1.04 1.01 – 1.08 0.0235 2962 29648 all phecode
368.1 Amblyopia Sense Organs 0.997 0.913 – 1.09 0.956 532 5322 all phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.01 0.938 – 1.09 0.767 727 7288 all phecode
368.3 Anisometropia Sense Organs 1.15 0.981 – 1.34 0.0851 154 1548 all phecode
368.4 Visual field defects Sense Organs 1.1 0.981 – 1.22 0.106 333 3327 all phecode
368.9 Subjective visual disturbances Sense Organs 1.13 1.04 – 1.22 0.00283 612 6115 all phecode
369 Infection of the eye Sense Organs 1.07 0.978 – 1.17 0.142 553 5544 all phecode
369.2 Eye infection, viral Sense Organs 1.05 0.874 – 1.25 0.616 125 1257 all phecode
369.5 Conjunctivitis, infectious Sense Organs 0.978 0.847 – 1.13 0.767 213 2128 all phecode
370 Keratitis Sense Organs 0.978 0.865 – 1.11 0.728 286 2855 all phecode
370.1 Corneal ulcer Sense Organs 0.937 0.789 – 1.11 0.46 141 1408 all phecode
371 Inflammation of the eye Sense Organs 1.02 0.985 – 1.06 0.245 3045 30480 all phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.02 0.929 – 1.12 0.69 482 4821 all phecode
371.3 Inflammation of eyelids Sense Organs 1.02 0.977 – 1.06 0.382 2353 23555 all phecode
372 Disorders of conjunctiva Sense Organs 0.984 0.913 – 1.06 0.681 760 7602 all phecode
374 Other disorders of eyelids Sense Organs 0.994 0.967 – 1.02 0.662 5680 56807 all phecode
374.1 Ectropion or entropion Sense Organs 0.955 0.896 – 1.02 0.158 1063 10645 all phecode
374.3 Ptosis of eyelid Sense Organs 0.992 0.946 – 1.04 0.753 1825 18232 all phecode
375 Disorders of lacrimal system Sense Organs 0.982 0.939 – 1.03 0.412 2204 22031 all phecode
375.2 Epiphora Sense Organs 0.959 0.895 – 1.03 0.238 898 8969 all phecode
376 Disorders of the orbit Sense Organs 0.939 0.748 – 1.18 0.59 86 859 all phecode
377 Disorders of optic nerve and visual pathways Sense Organs 1.04 0.932 – 1.16 0.5 361 3618 all phecode
377.1 Optic atrophy Sense Organs 1.04 0.791 – 1.36 0.801 56 570 all phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.98 0.817 – 1.18 0.828 125 1249 all phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.988 0.935 – 1.04 0.665 1410 14116 all phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.973 0.909 – 1.04 0.429 909 9082 all phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 0.957 0.832 – 1.1 0.54 213 2138 all phecode
378.5 Paralytic strabismus Sense Organs 1.08 0.959 – 1.23 0.196 275 2755 all phecode
379 Other disorders of eye Sense Organs 0.981 0.948 – 1.01 0.266 3703 37063 all phecode
379.2 Disorders of vitreous body Sense Organs 0.982 0.929 – 1.04 0.534 1367 13665 all phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.987 0.941 – 1.04 0.605 1813 18134 all phecode
379.4 Anomalies of pupillary function Sense Organs 1.07 0.839 – 1.36 0.588 71 710 all phecode
379.5 Disorders of iris and ciliary body Sense Organs 1.02 0.917 – 1.12 0.77 400 4028 all phecode
379.9 Pain, swelling or discharge of eye Sense Organs 1.05 0.897 – 1.22 0.563 169 1690 all phecode
380 Disorders of external ear Sense Organs 1.03 0.952 – 1.12 0.447 642 6413 all phecode
380.1 Otitis externa Sense Organs 1.06 0.968 – 1.16 0.209 509 5107 all phecode
380.4 Impacted cerumen Sense Organs 0.983 0.885 – 1.09 0.752 362 3614 all phecode
381 Otitis media and Eustachian tube disorders Sense Organs 0.987 0.944 – 1.03 0.568 2150 21493 all phecode
381.1 Otitis media Sense Organs 0.981 0.935 – 1.03 0.454 1767 17668 all phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1 0.934 – 1.07 0.968 852 8524 all phecode
381.2 Eustachian tube disorders Sense Organs 1.02 0.881 – 1.18 0.796 193 1929 all phecode
381.3 Mastoiditis & related conditions Sense Organs 1.03 0.879 – 1.2 0.725 171 1709 all phecode
381.9 Otorrhea Sense Organs 0.978 0.865 – 1.11 0.727 281 2807 all phecode
382 Otalgia Sense Organs 1.12 0.994 – 1.25 0.0628 308 3084 all phecode
383 Otosclerosis Sense Organs 1.02 0.904 – 1.14 0.79 309 3090 all phecode
384 Other disorders of tympanic membrane Sense Organs 1.01 0.954 – 1.07 0.734 1299 12991 all phecode
384.4 Perforation of tympanic membrane Sense Organs 1.01 0.95 – 1.08 0.706 1043 10432 all phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.05 0.974 – 1.13 0.211 783 7837 all phecode
385.3 Cholesteatoma Sense Organs 1.04 0.952 – 1.13 0.416 607 6078 all phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.08 0.951 – 1.24 0.225 241 2409 all phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.07 1.02 – 1.13 0.00464 1736 17373 all phecode
386.1 Meniere's disease Sense Organs 1.12 1.03 – 1.21 0.01 576 5768 all phecode
386.2 Peripheral or central vertigo Sense Organs 1 0.904 – 1.12 0.931 377 3763 all phecode
386.3 Labyrinthitis Sense Organs 1.03 0.961 – 1.11 0.37 765 7664 all phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.01 0.977 – 1.04 0.637 4582 45806 all phecode
388 Other disorders of ear Sense Organs 1.18 1.02 – 1.36 0.0218 202 2017 all phecode
389 Hearing loss Sense Organs 1.01 0.975 – 1.04 0.697 4188 41944 all phecode
389.1 Sensorineural hearing loss Sense Organs 1.02 0.931 – 1.13 0.629 456 4553 all phecode
389.2 Conductive hearing loss Sense Organs 0.934 0.847 – 1.03 0.177 450 4497 all phecode
389.4 Tinnitus Sense Organs 0.975 0.89 – 1.07 0.593 513 5134 all phecode
394 Rheumatic disease of the heart valves Circulatory System 1.01 0.981 – 1.04 0.49 4899 48974 all phecode
394.2 Mitral valve disease Circulatory System 1.01 0.977 – 1.05 0.459 2993 29922 all phecode
394.3 Aortic valve disease Circulatory System 1.01 0.955 – 1.07 0.689 1282 12814 all phecode
394.7 Disease of tricuspid valve Circulatory System 1.05 0.983 – 1.11 0.157 1058 10566 all phecode
395 Heart valve disorders Circulatory System 1.02 0.986 – 1.05 0.279 4223 42219 all phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.02 0.98 – 1.06 0.363 2891 28900 all phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.13 0.998 – 1.27 0.0546 276 2766 all phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.17 0.966 – 1.42 0.107 105 1039 all phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.978 0.795 – 1.2 0.835 97 970 all phecode
395.6 Heart valve replaced Circulatory System 0.993 0.941 – 1.05 0.793 1495 14942 all phecode
396 Abnormal heart sounds Circulatory System 1.04 0.979 – 1.11 0.189 1048 10468 all phecode
401 Hypertension Circulatory System 1.01 0.997 – 1.01 0.234 73956 266957 all phecode
401.1 Essential hypertension Circulatory System 1 0.996 – 1.01 0.259 73731 266739 all phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.01 0.964 – 1.06 0.683 1898 19031 all phecode
401.21 Hypertensive heart disease Circulatory System 1.01 0.909 – 1.12 0.859 370 3699 all phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.01 0.958 – 1.06 0.729 1543 15483 all phecode
401.3 Other hypertensive complications Circulatory System 0.987 0.829 – 1.18 0.886 144 1438 all phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.04 0.987 – 1.1 0.138 1479 14786 all phecode
411 Ischemic Heart Disease Circulatory System 0.996 0.984 – 1.01 0.467 31245 210714 all phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.01 0.977 – 1.03 0.727 5152 51498 all phecode
411.2 Myocardial infarction Circulatory System 1 0.984 – 1.02 0.757 11950 112699 all phecode
411.3 Angina pectoris Circulatory System 0.982 0.966 – 0.998 0.0277 15888 143745 all phecode
411.4 Coronary atherosclerosis Circulatory System 0.996 0.982 – 1.01 0.641 20171 154621 all phecode
411.41 Aneurysm and dissection of heart Circulatory System 0.947 0.876 – 1.02 0.171 700 6997 all phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 0.999 0.982 – 1.02 0.903 15290 131798 all phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.01 0.957 – 1.08 0.632 1218 12166 all phecode
414 Other forms of chronic heart disease Circulatory System 0.957 0.912 – 1 0.0779 1823 18228 all phecode
414.2 ASCVD Circulatory System 1.13 0.888 – 1.44 0.32 72 719 all phecode
415 Pulmonary heart disease Circulatory System 1.01 0.981 – 1.04 0.443 4476 44810 all phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 1.08 0.867 – 1.35 0.485 75 750 all phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.11 1.02 – 1.2 0.0168 601 6002 all phecode
415.21 Primary pulmonary hypertension Circulatory System 1.1 0.999 – 1.21 0.0518 448 4475 all phecode
416 Cardiomegaly Circulatory System 1 0.965 – 1.04 0.852 2680 26793 all phecode
418 Nonspecific chest pain Circulatory System 1.01 0.996 – 1.02 0.194 28599 270106 all phecode
418.1 Precordial pain Circulatory System 1.01 0.971 – 1.04 0.776 3551 35541 all phecode
420 Carditis Circulatory System 1.03 0.988 – 1.08 0.159 2106 21053 all phecode
420.1 Myocarditis Circulatory System 0.988 0.826 – 1.18 0.899 127 1267 all phecode
420.2 Pericarditis Circulatory System 1.06 1 – 1.12 0.0519 1338 13371 all phecode
420.21 Acute pericarditis Circulatory System 1.08 0.947 – 1.24 0.247 223 2227 all phecode
420.22 Chronic pericarditis Circulatory System 1.06 0.886 – 1.28 0.506 113 1129 all phecode
420.3 Endocarditis Circulatory System 1.01 0.939 – 1.1 0.715 719 7194 all phecode
425 Cardiomyopathy Circulatory System 0.98 0.924 – 1.04 0.491 1271 12699 all phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 0.969 0.913 – 1.03 0.293 1236 12349 all phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 0.903 0.755 – 1.08 0.264 133 1329 all phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.04 0.889 – 1.23 0.599 163 1629 all phecode
425.8 Other cardiomyopathy Circulatory System 1.26 0.992 – 1.61 0.0577 60 600 all phecode
426 Cardiac conduction disorders Circulatory System 0.984 0.959 – 1.01 0.19 6910 69146 all phecode
426.2 Atrioventricular [AV] block Circulatory System 0.96 0.917 – 1 0.0722 2114 21162 all phecode
426.21 First degree AV block Circulatory System 0.964 0.903 – 1.03 0.274 986 9867 all phecode
426.23 Second degree AV block Circulatory System 0.989 0.898 – 1.09 0.826 452 4515 all phecode
426.24 Atrioventricular block, complete Circulatory System 0.991 0.911 – 1.08 0.824 587 5868 all phecode
426.25 Other heart block Circulatory System 1 0.835 – 1.2 0.999 131 1318 all phecode
426.3 Bundle branch block Circulatory System 0.995 0.96 – 1.03 0.787 3336 33359 all phecode
426.31 Right bundle branch block Circulatory System 1.01 0.954 – 1.06 0.834 1494 14933 all phecode
426.32 Left bundle branch block Circulatory System 0.98 0.933 – 1.03 0.426 1750 17503 all phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.979 0.855 – 1.12 0.762 233 2328 all phecode
426.8 Other cardiac conduction disorders Circulatory System 1.33 1.03 – 1.72 0.0279 60 600 all phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 0.984 0.944 – 1.03 0.452 2475 24774 all phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.985 0.944 – 1.03 0.503 2274 22762 all phecode
427 Cardiac dysrhythmias Circulatory System 0.992 0.978 – 1 0.212 24207 206016 all phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.01 0.971 – 1.04 0.697 3199 32017 all phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 0.993 0.952 – 1.04 0.762 2344 23474 all phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 1.02 0.953 – 1.09 0.576 936 9365 all phecode
427.2 Atrial fibrillation and flutter Circulatory System 0.993 0.976 – 1.01 0.403 14628 133501 all phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.979 0.944 – 1.02 0.256 3228 32281 all phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.981 0.925 – 1.04 0.526 1193 11915 all phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.941 0.843 – 1.05 0.276 344 3437 all phecode
427.42 Cardiac arrest Circulatory System 0.99 0.927 – 1.06 0.751 990 9890 all phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 0.963 0.901 – 1.03 0.266 952 9541 all phecode
427.6 Premature beats Circulatory System 1.03 0.943 – 1.12 0.511 535 5358 all phecode
427.61 Supraventricular premature beats Circulatory System 0.926 0.763 – 1.12 0.437 117 1168 all phecode
427.7 Tachycardia NOS Circulatory System 0.976 0.934 – 1.02 0.288 2185 21865 all phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.02 0.925 – 1.13 0.667 402 4029 all phecode
427.9 Palpitations Circulatory System 1 0.967 – 1.03 0.995 3811 38105 all phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.02 0.992 – 1.05 0.156 5605 56018 all phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.02 0.975 – 1.07 0.385 2111 21108 all phecode
428.2 Heart failure NOS Circulatory System 1.02 0.99 – 1.05 0.191 4455 44524 all phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 0.99 0.917 – 1.07 0.806 716 7168 all phecode
429.1 Heart transplant/surgery Circulatory System 0.787 0.596 – 1.04 0.0906 64 639 all phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.954 0.871 – 1.05 0.317 522 5211 all phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.1 0.95 – 1.26 0.209 196 1978 all phecode
430 Intracranial hemorrhage Circulatory System 1.03 0.985 – 1.08 0.188 1883 18825 all phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.06 0.989 – 1.14 0.0963 836 8353 all phecode
430.2 Intracerebral hemorrhage Circulatory System 1 0.929 – 1.08 0.994 765 7656 all phecode
430.3 Subdural hemorrhage Circulatory System 1.03 0.907 – 1.16 0.681 267 2667 all phecode
433 Cerebrovascular disease Circulatory System 1 0.979 – 1.02 0.923 8749 87456 all phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.04 0.978 – 1.1 0.22 1185 11825 all phecode
433.12 Cerebral atherosclerosis Circulatory System 1.12 0.985 – 1.28 0.0818 227 2267 all phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.988 0.957 – 1.02 0.457 4233 42320 all phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.962 0.915 – 1.01 0.132 1680 16794 all phecode
433.3 Cerebral ischemia Circulatory System 1 0.967 – 1.04 0.819 2895 28989 all phecode
433.31 Transient cerebral ischemia Circulatory System 1.01 0.962 – 1.05 0.82 2135 21379 all phecode
433.5 Cerebral aneurysm Circulatory System 0.983 0.885 – 1.09 0.75 394 3939 all phecode
433.8 Late effects of cerebrovascular disease Circulatory System 0.997 0.942 – 1.06 0.924 1279 12783 all phecode
440 Atherosclerosis Circulatory System 0.963 0.91 – 1.02 0.182 1380 13822 all phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.04 0.862 – 1.27 0.656 113 1129 all phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.936 0.87 – 1.01 0.0767 805 8070 all phecode
440.9 Atherosclerosis of aorta Circulatory System 0.941 0.831 – 1.07 0.341 287 2867 all phecode
441 Vascular insufficiency of intestine Circulatory System 0.963 0.886 – 1.05 0.368 614 6154 all phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.883 0.779 – 1 0.0536 283 2827 all phecode
442 Other aneurysm Circulatory System 1.02 0.974 – 1.07 0.382 1892 18959 all phecode
442.1 Aortic aneurysm Circulatory System 1.02 0.965 – 1.07 0.521 1458 14625 all phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.02 0.956 – 1.09 0.519 931 9341 all phecode
442.2 Aneurysm of iliac artery Circulatory System 1.15 0.947 – 1.39 0.16 102 1019 all phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 1.01 0.868 – 1.18 0.874 169 1696 all phecode
442.4 Arterial dissection Circulatory System 1.3 1.01 – 1.67 0.0442 54 549 all phecode
442.8 Aneurysm of other specified artery Circulatory System 0.999 0.866 – 1.15 0.986 203 2028 all phecode
443 Peripheral vascular disease Circulatory System 1.01 0.974 – 1.04 0.684 3921 39273 all phecode
443.1 Raynaud's syndrome Circulatory System 1.02 0.96 – 1.08 0.536 1145 11438 all phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1 0.903 – 1.11 0.977 384 3878 all phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1 0.969 – 1.04 0.884 3686 36906 all phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.998 0.959 – 1.04 0.933 2579 25846 all phecode
444 Arterial embolism and thrombosis Circulatory System 1.02 0.951 – 1.09 0.623 922 9251 all phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.04 0.953 – 1.13 0.395 554 5552 all phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.02 0.951 – 1.1 0.558 822 8226 all phecode
446.4 Wegener's granulomatosis Circulatory System 1.12 0.976 – 1.3 0.103 188 1878 all phecode
446.5 Giant cell arteritis Circulatory System 1.04 0.941 – 1.16 0.411 388 3879 all phecode
446.9 Arteritis NOS Circulatory System 1.01 0.886 – 1.16 0.858 239 2400 all phecode
447 Other disorders of arteries and arterioles Circulatory System 0.98 0.926 – 1.04 0.485 1327 13316 all phecode
447.1 Stricture of artery Circulatory System 0.991 0.924 – 1.06 0.802 868 8712 all phecode
448 Disease of capillaries Circulatory System 0.948 0.798 – 1.13 0.539 142 1420 all phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.01 0.931 – 1.09 0.88 704 7034 all phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.01 0.982 – 1.05 0.382 3955 39683 all phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.02 0.989 – 1.06 0.186 3683 36977 all phecode
452 Other venous embolism and thrombosis Circulatory System 0.977 0.895 – 1.07 0.6 564 5645 all phecode
454 Varicose veins Circulatory System 1 0.985 – 1.02 0.671 11180 112047 all phecode
454.1 Varicose veins of lower extremity Circulatory System 1.01 0.987 – 1.03 0.543 11503 115272 all phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.889 0.816 – 0.967 0.00637 624 6325 all phecode
455 Hemorrhoids Circulatory System 1 0.989 – 1.02 0.748 23452 234585 all phecode
456 Chronic venous insufficiency [CVI] Circulatory System 0.999 0.858 – 1.16 0.987 184 1868 all phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.09 0.893 – 1.34 0.385 97 967 all phecode
458 Hypotension Circulatory System 1 0.978 – 1.03 0.749 5769 57772 all phecode
458.1 Orthostatic hypotension Circulatory System 0.982 0.929 – 1.04 0.534 1335 13376 all phecode
458.2 Iatrogenic hypotension Circulatory System 1.02 0.894 – 1.17 0.745 235 2348 all phecode
458.9 Hypotension NOS Circulatory System 1 0.968 – 1.04 0.883 3494 35005 all phecode
459 Other disorders of circulatory system Circulatory System 0.995 0.979 – 1.01 0.518 16268 160790 all phecode
459.1 Hemorrhage NOS Circulatory System 1.02 0.866 – 1.21 0.786 142 1420 all phecode
459.9 Circulatory disease NEC Circulatory System 0.995 0.979 – 1.01 0.522 16103 159422 all phecode
464 Acute sinusitis Respiratory 1.09 0.941 – 1.25 0.257 196 1957 all phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 0.978 0.937 – 1.02 0.315 2283 22827 all phecode
465.2 Acute pharyngitis Respiratory 1.02 0.949 – 1.1 0.59 835 8348 all phecode
465.4 Acute laryngitis and tracheitis Respiratory 0.972 0.83 – 1.14 0.726 165 1649 all phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.03 0.997 – 1.06 0.0786 4654 46553 all phecode
471 Nasal polyps Respiratory 1.02 0.984 – 1.06 0.281 3297 32973 all phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.01 0.942 – 1.07 0.855 960 9594 all phecode
473 Diseases of the larynx and vocal cords Respiratory 0.997 0.957 – 1.04 0.885 2554 25548 all phecode
473.1 Chronic laryngitis Respiratory 0.865 0.704 – 1.06 0.164 104 1038 all phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 0.994 0.877 – 1.13 0.923 264 2647 all phecode
473.4 Voice disturbance Respiratory 0.992 0.932 – 1.06 0.797 1080 10789 all phecode
474 Acute and chronic tonsillitis Respiratory 1.03 0.98 – 1.08 0.26 1772 17710 all phecode
474.1 Acute tonsillitis Respiratory 1.08 0.992 – 1.18 0.0758 549 5486 all phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.02 0.96 – 1.09 0.504 1122 11199 all phecode
475 Chronic sinusitis Respiratory 1 0.964 – 1.05 0.86 2589 25882 all phecode
476 Allergic rhinitis Respiratory 0.991 0.929 – 1.06 0.775 1055 10563 all phecode
477 Epistaxis or throat hemorrhage Respiratory 0.979 0.939 – 1.02 0.309 2447 24452 all phecode
478 Throat pain Respiratory 1.09 0.986 – 1.21 0.0912 377 3789 all phecode
479 Other upper respiratory disease Respiratory 1.01 0.978 – 1.04 0.567 4074 40737 all phecode
480 Pneumonia Respiratory 1.01 0.987 – 1.03 0.498 10336 103397 all phecode
480.1 Bacterial pneumonia Respiratory 1.01 0.983 – 1.03 0.545 6637 66410 all phecode
480.11 Pneumococcal pneumonia Respiratory 1.01 0.981 – 1.03 0.601 5883 58863 all phecode
480.12 Pseudomonal pneumonia Respiratory 1.02 0.831 – 1.26 0.836 93 929 all phecode
480.2 Viral pneumonia Respiratory 0.818 0.631 – 1.06 0.129 72 720 all phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.04 0.851 – 1.28 0.69 99 989 all phecode
480.5 Bronchopneumonia and lung abscess Respiratory 1 0.931 – 1.08 0.966 794 7951 all phecode
481 Influenza Respiratory 1.01 0.898 – 1.13 0.919 328 3278 all phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.08 0.93 – 1.26 0.313 193 1930 all phecode
495 Asthma Respiratory 0.996 0.983 – 1.01 0.564 25689 250406 all phecode
495.2 Asthma with exacerbation Respiratory 0.871 0.763 – 0.995 0.0414 250 2510 all phecode
496 Chronic airway obstruction Respiratory 0.996 0.977 – 1.02 0.726 10424 101546 all phecode
496.1 Emphysema Respiratory 0.986 0.938 – 1.04 0.565 1743 17438 all phecode
496.2 Chronic bronchitis Respiratory 1.01 0.972 – 1.05 0.637 2947 29498 all phecode
496.21 Obstructive chronic bronchitis Respiratory 1.01 0.967 – 1.05 0.756 2706 27081 all phecode
496.3 Bronchiectasis Respiratory 1.01 0.959 – 1.05 0.814 1885 18859 all phecode
497 Bronchitis Respiratory 0.907 0.832 – 0.988 0.0251 626 6267 all phecode
500 Lung disease due to external agents Respiratory 0.991 0.898 – 1.09 0.865 412 4099 all phecode
500.1 Extrinsic allergic alveolitis Respiratory 0.861 0.681 – 1.09 0.213 79 784 all phecode
500.2 Pneumoconiosis Respiratory 1.04 0.914 – 1.18 0.563 243 2409 all phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.03 0.95 – 1.12 0.473 656 6557 all phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.03 0.959 – 1.1 0.466 917 9193 all phecode
503 Pulmonary congestion and hypostasis Respiratory 0.847 0.77 – 0.932 0.000672 508 5079 all phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.08 0.964 – 1.21 0.185 328 3280 all phecode
505 Other pulmonary inflamation or edema Respiratory 1.02 0.79 – 1.32 0.864 61 610 all phecode
506 Empyema and pneumothorax Respiratory 1.01 0.951 – 1.07 0.736 1133 11362 all phecode
507 Pleurisy; pleural effusion Respiratory 1 0.979 – 1.03 0.725 6419 64252 all phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.959 0.915 – 1 0.0733 1996 19947 all phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.01 0.966 – 1.05 0.806 2599 26031 all phecode
509.1 Respiratory failure Respiratory 1.01 0.961 – 1.05 0.822 2068 20708 all phecode
509.2 Respiratory insufficiency Respiratory 1.01 0.96 – 1.06 0.764 1806 18106 all phecode
509.5 Respiratory arrest Respiratory 1.21 1.02 – 1.42 0.0249 143 1429 all phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1.03 0.931 – 1.15 0.534 386 3863 all phecode
510 Other diseases of lung Respiratory 1.1 1.02 – 1.18 0.014 755 7554 all phecode
512 Other symptoms of respiratory system Respiratory 1.02 1 – 1.05 0.0401 9031 90349 all phecode
512.1 Wheezing Respiratory 1.06 0.92 – 1.22 0.425 220 2196 all phecode
512.2 Painful respiration Respiratory 1.15 0.998 – 1.32 0.0528 207 2075 all phecode
512.7 Shortness of breath Respiratory 1.02 0.996 – 1.05 0.095 5842 58498 all phecode
512.8 Cough Respiratory 1.03 0.993 – 1.07 0.115 2866 28642 all phecode
512.9 Other dyspnea Respiratory 0.986 0.921 – 1.06 0.683 914 9124 all phecode
513 Respiratory abnormalities Respiratory 0.963 0.886 – 1.05 0.383 611 6112 all phecode
513.3 Hypoventilation Respiratory 1.04 0.833 – 1.31 0.706 83 830 all phecode
513.4 Hyperventilation Respiratory 0.881 0.775 – 1 0.052 278 2778 all phecode
513.8 Disorders of diaphragm Respiratory 1.06 0.903 – 1.25 0.465 153 1538 all phecode
514 Abnormal findings examination of lungs Respiratory 1 0.96 – 1.04 0.953 2465 24673 all phecode
516 Abnormal sputum Respiratory 1.01 0.969 – 1.06 0.576 2132 21335 all phecode
516.1 Hemoptysis Respiratory 1.02 0.972 – 1.06 0.477 2073 20745 all phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 0.99 0.97 – 1.01 0.374 9366 93681 all phecode
519.2 Respiratory complications Respiratory 1.08 0.961 – 1.2 0.203 327 3279 all phecode
519.8 Other diseases of respiratory system, NEC Respiratory 0.985 0.964 – 1.01 0.174 8853 88522 all phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 0.994 0.883 – 1.12 0.914 303 3049 all phecode
520 Disorders of tooth development Digestive 1.01 0.967 – 1.06 0.606 2038 20354 all phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.837 0.625 – 1.12 0.23 53 530 all phecode
520.2 Disturbances in tooth eruption Digestive 0.987 0.947 – 1.03 0.55 2356 23539 all phecode
521 Diseases of hard tissues of teeth Digestive 0.998 0.961 – 1.04 0.901 3016 30245 all phecode
521.1 Dental caries Digestive 0.997 0.96 – 1.03 0.875 3026 30353 all phecode
522 Diseases of pulp and periapical tissues Digestive 1.02 0.97 – 1.07 0.457 1774 17750 all phecode
522.5 Periapical abscess Digestive 1.03 0.973 – 1.1 0.294 1172 11731 all phecode
523 Gingival and periodontal diseases Digestive 1.03 0.977 – 1.08 0.294 1681 16812 all phecode
523.1 Gingivitis Digestive 1.03 0.853 – 1.24 0.774 113 1127 all phecode
523.3 Periodontitis (acute or chronic) Digestive 1.03 0.973 – 1.1 0.288 1165 11650 all phecode
523.31 Acute periodontitis Digestive 0.988 0.912 – 1.07 0.768 666 6667 all phecode
523.32 Chronic periodontitis Digestive 1.06 0.975 – 1.16 0.168 560 5594 all phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.06 0.948 – 1.18 0.311 331 3307 all phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1.01 0.9 – 1.14 0.844 305 3046 all phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.97 0.932 – 1.01 0.143 2668 26728 all phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.11 0.876 – 1.39 0.398 72 720 all phecode
526 Diseases of the jaws Digestive 1.03 0.964 – 1.1 0.365 928 9279 all phecode
526.1 Cysts of the jaws Digestive 0.984 0.879 – 1.1 0.778 329 3289 all phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.15 0.891 – 1.49 0.282 61 610 all phecode
526.4 Temporomandibular joint disorders Digestive 1.07 0.938 – 1.22 0.318 240 2406 all phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.07 0.942 – 1.23 0.285 233 2336 all phecode
526.5 Inflammatory conditions of jaw Digestive 0.994 0.815 – 1.21 0.952 110 1098 all phecode
526.9 Jaw disease NOS Digestive 1.01 0.878 – 1.16 0.908 233 2329 all phecode
527 Diseases of the salivary glands Digestive 0.997 0.923 – 1.08 0.949 694 6943 all phecode
527.1 Hypertrophy of salivary gland Digestive 1.03 0.828 – 1.28 0.788 84 838 all phecode
527.2 Sialoadenitis Digestive 0.95 0.853 – 1.06 0.349 365 3656 all phecode
527.7 Disturbance of salivary secretion Digestive 1.04 0.804 – 1.35 0.762 62 619 all phecode
527.8 Other specified diseases of the salivary glands Digestive 1.01 0.839 – 1.21 0.937 120 1200 all phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 1 0.968 – 1.03 0.995 3873 38741 all phecode
528.1 Stomatitis and mucositis Digestive 1.05 0.96 – 1.16 0.274 468 4675 all phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.05 0.946 – 1.16 0.367 389 3884 all phecode
528.12 Oral aphthae Digestive 1.1 0.88 – 1.37 0.409 84 840 all phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.12 0.968 – 1.3 0.125 179 1790 all phecode
528.4 Cysts of oral soft tissues Digestive 1.01 0.837 – 1.22 0.925 122 1219 all phecode
528.41 Cyst of the salivary gland Digestive 0.946 0.763 – 1.17 0.615 94 940 all phecode
528.5 Diseases of lips Digestive 1.03 0.952 – 1.11 0.468 681 6813 all phecode
528.6 Leukoplakia of oral mucosa Digestive 0.885 0.786 – 0.996 0.0424 308 3079 all phecode
528.7 Sialolithiasis Digestive 0.984 0.878 – 1.1 0.778 314 3138 all phecode
529 Diseases and other conditions of the tongue Digestive 1 0.943 – 1.06 0.987 1232 12312 all phecode
529.1 Glossitis Digestive 1.1 0.976 – 1.23 0.12 299 2986 all phecode
530 Diseases of esophagus Digestive 1.01 0.994 – 1.02 0.321 33453 279172 all phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.01 0.998 – 1.02 0.114 31253 272429 all phecode
530.11 GERD Digestive 1.01 0.998 – 1.03 0.0993 22633 225879 all phecode
530.12 Ulcer of esophagus Digestive 1.03 1 – 1.06 0.053 5203 52068 all phecode
530.14 Reflux esophagitis Digestive 1.02 1 – 1.04 0.0192 10444 104493 all phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 0.954 0.907 – 1 0.0673 1681 16808 all phecode
530.3 Stricture and stenosis of esophagus Digestive 1.03 0.98 – 1.08 0.263 1869 18684 all phecode
530.5 Disorders of esophageal motility Digestive 0.968 0.892 – 1.05 0.43 635 6365 all phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.01 0.858 – 1.18 0.929 153 1527 all phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.944 0.844 – 1.06 0.31 341 3416 all phecode
530.9 Heartburn Digestive 1.01 0.967 – 1.06 0.611 2087 20881 all phecode
531 Peptic ulcer (excl. esophageal) Digestive 0.988 0.964 – 1.01 0.334 7103 71066 all phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 1.01 0.933 – 1.1 0.778 637 6374 all phecode
531.2 Gastric ulcer Digestive 0.977 0.946 – 1.01 0.149 4091 40941 all phecode
531.3 Duodenal ulcer Digestive 0.995 0.958 – 1.03 0.775 2999 30005 all phecode
531.4 Peptic ulcer, site unspecified Digestive 0.956 0.866 – 1.06 0.372 427 4268 all phecode
532 Dysphagia Digestive 0.991 0.966 – 1.02 0.508 6427 64329 all phecode
535 Gastritis and duodenitis Digestive 0.993 0.981 – 1.01 0.271 28078 261548 all phecode
535.1 Acute gastritis Digestive 0.974 0.917 – 1.03 0.383 1183 11833 all phecode
535.2 Atrophic gastritis Digestive 0.977 0.878 – 1.09 0.667 370 3687 all phecode
535.6 Duodenitis Digestive 0.998 0.975 – 1.02 0.893 7592 75928 all phecode
535.8 Other specified gastritis Digestive 0.996 0.973 – 1.02 0.71 8071 80763 all phecode
535.9 Gastritis and duodenitis, NOS Digestive 0.981 0.815 – 1.18 0.838 120 1191 all phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.01 0.889 – 1.14 0.913 259 2576 all phecode
537 Other disorders of stomach and duodenum Digestive 0.992 0.958 – 1.03 0.673 3391 33907 all phecode
540 Appendiceal conditions Digestive 0.969 0.934 – 1.01 0.0945 3088 30890 all phecode
540.1 Appendicitis Digestive 0.965 0.929 – 1 0.0654 2895 28963 all phecode
540.11 Acute appendicitis Digestive 0.964 0.926 – 1 0.077 2601 26019 all phecode
550 Abdominal hernia Digestive 1 0.992 – 1.01 0.669 45429 282640 all phecode
550.1 Inguinal hernia Digestive 0.995 0.978 – 1.01 0.54 15794 123247 all phecode
550.2 Diaphragmatic hernia Digestive 1.01 0.993 – 1.02 0.42 26494 238953 all phecode
550.3 Femoral hernia Digestive 1.02 0.939 – 1.1 0.682 651 6504 all phecode
550.4 Umbilical hernia Digestive 1.02 0.984 – 1.05 0.296 3705 37072 all phecode
550.5 Ventral hernia Digestive 1 0.969 – 1.04 0.844 3435 34338 all phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1 0.974 – 1.04 0.784 4444 44442 all phecode
555.1 Regional enteritis Digestive 1 0.953 – 1.05 0.968 1734 17340 all phecode
555.2 Ulcerative colitis Digestive 1.01 0.97 – 1.04 0.745 3178 31786 all phecode
555.21 Ulcerative colitis (chronic) Digestive 1.01 0.924 – 1.1 0.832 538 5382 all phecode
556 Ulceration of the lower GI tract Digestive 1.08 1.02 – 1.15 0.0116 1055 10592 all phecode
556.1 Ulceration of intestine Digestive 1.03 0.948 – 1.11 0.525 670 6714 all phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.961 0.854 – 1.08 0.51 299 2987 all phecode
557.1 Celiac disease Digestive 0.973 0.927 – 1.02 0.262 1837 18388 all phecode
558 Noninfectious gastroenteritis Digestive 1.02 1 – 1.04 0.0151 15492 155105 all phecode
559 Ileostomy status Digestive 0.988 0.938 – 1.04 0.628 1656 16541 all phecode
560 Intestinal obstruction without mention of hernia Digestive 1.01 0.976 – 1.04 0.606 3936 39337 all phecode
560.1 Paralytic ileus Digestive 1 0.918 – 1.1 0.94 523 5231 all phecode
560.2 Impaction of intestine Digestive 0.993 0.878 – 1.12 0.917 268 2671 all phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.97 0.903 – 1.04 0.403 832 8317 all phecode
560.4 Other intestinal obstruction Digestive 1 0.968 – 1.04 0.858 3358 33550 all phecode
561 Symptoms involving digestive system Digestive 1.01 0.994 – 1.03 0.196 15772 157686 all phecode
561.1 Diarrhea Digestive 1.06 0.961 – 1.16 0.257 466 4653 all phecode
561.2 Flatulence Digestive 1.03 0.984 – 1.09 0.19 1687 16859 all phecode
562 Diverticulosis and diverticulitis Digestive 1 0.989 – 1.01 0.838 26714 211692 all phecode
562.1 Diverticulosis Digestive 1 0.988 – 1.01 0.872 26672 211642 all phecode
563 Constipation Digestive 1 0.983 – 1.02 0.764 10314 103140 all phecode
564 Functional digestive disorders Digestive 0.999 0.985 – 1.01 0.897 21639 209949 all phecode
564.1 Irritable Bowel Syndrome Digestive 0.995 0.967 – 1.02 0.703 5508 55117 all phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 0.997 0.948 – 1.05 0.92 1645 16457 all phecode
564.9 Personal history of diseases of digestive system Digestive 1 0.983 – 1.02 0.973 15186 151648 all phecode
565 Anal and rectal conditions Digestive 0.995 0.978 – 1.01 0.547 14744 147535 all phecode
565.1 Anal and rectal polyp Digestive 0.996 0.972 – 1.02 0.729 7351 73533 all phecode
567 Peritonitis and retroperitoneal infections Digestive 0.982 0.917 – 1.05 0.6 929 9293 all phecode
568 Other disorders of peritoneum Digestive 1.02 0.981 – 1.05 0.359 3262 32602 all phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.01 0.978 – 1.05 0.44 3101 30987 all phecode
569 Other disorders of intestine Digestive 1.01 0.98 – 1.04 0.479 4192 41922 all phecode
569.1 Toxic gastroenteritis and colitis Digestive 0.927 0.78 – 1.1 0.384 148 1479 all phecode
569.2 Gastrointestinal complications Digestive 1.07 0.98 – 1.18 0.128 486 4868 all phecode
571 Chronic liver disease and cirrhosis Digestive 1 0.964 – 1.04 0.973 2957 29628 all phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.04 0.992 – 1.1 0.104 1689 16917 all phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 0.96 0.788 – 1.17 0.688 113 1139 all phecode
571.6 Primary biliary cirrhosis Digestive 1.02 0.892 – 1.16 0.818 257 2568 all phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 0.936 0.876 – 1 0.0533 976 9804 all phecode
571.81 Portal hypertension Digestive 0.942 0.861 – 1.03 0.19 528 5285 all phecode
572 Ascites (non malignant) Digestive 1.01 0.955 – 1.06 0.837 1544 15454 all phecode
573 Other disorders of liver Digestive 1 0.951 – 1.06 0.935 1496 14982 all phecode
573.2 Liver replaced by transplant Digestive 0.916 0.736 – 1.14 0.434 96 960 all phecode
573.3 Hepatomegaly Digestive 0.977 0.868 – 1.1 0.705 297 2968 all phecode
573.5 Jaundice (not of newborn) Digestive 0.976 0.911 – 1.05 0.483 896 8955 all phecode
573.7 Abnormal results of function study of liver Digestive 1.01 0.973 – 1.04 0.661 3454 34597 all phecode
573.9 Abnormal serum enzyme levels Digestive 1.03 0.892 – 1.18 0.727 209 2089 all phecode
574 Cholelithiasis and cholecystitis Digestive 0.997 0.98 – 1.01 0.678 15607 156123 all phecode
574.1 Cholelithiasis Digestive 0.993 0.976 – 1.01 0.441 13549 135537 all phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.963 0.913 – 1.02 0.17 1506 15072 all phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.02 0.993 – 1.05 0.135 5429 54289 all phecode
574.2 Calculus of bile duct Digestive 1.02 0.975 – 1.06 0.461 2620 26191 all phecode
574.3 Cholecystitis without cholelithiasis Digestive 0.974 0.937 – 1.01 0.197 2748 27523 all phecode
575 Other biliary tract disease Digestive 0.997 0.964 – 1.03 0.836 3867 38724 all phecode
575.1 Cholangitis Digestive 0.96 0.876 – 1.05 0.387 495 4945 all phecode
575.2 Obstruction of bile duct Digestive 0.963 0.894 – 1.04 0.315 774 7756 all phecode
575.6 Cholesterolosis of gallbladder Digestive 0.96 0.872 – 1.06 0.397 458 4577 all phecode
575.7 Other disorders of gallbladder Digestive 1.03 0.971 – 1.08 0.373 1408 14107 all phecode
575.8 Other disorders of biliary tract Digestive 1 0.939 – 1.07 0.972 1036 10367 all phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.02 0.913 – 1.13 0.756 348 3488 all phecode
577 Diseases of pancreas Digestive 1.01 0.97 – 1.05 0.636 2668 26677 all phecode
577.1 Acute pancreatitis Digestive 1.02 0.97 – 1.06 0.502 1996 19962 all phecode
577.2 Chronic pancreatitis Digestive 0.913 0.833 – 1 0.0518 515 5149 all phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.06 0.951 – 1.17 0.304 365 3650 all phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.993 – 1.02 0.349 20626 206278 all phecode
578.1 Hematemesis Digestive 0.977 0.933 – 1.02 0.334 1958 19564 all phecode
578.2 Blood in stool Digestive 0.984 0.945 – 1.02 0.427 2626 26283 all phecode
578.8 Hemorrhage of rectum and anus Digestive 1.01 0.992 – 1.03 0.298 13073 130745 all phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 0.998 0.97 – 1.03 0.89 5275 52787 all phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.01 0.962 – 1.07 0.63 1548 15498 all phecode
579.2 Splenomegaly Digestive 0.984 0.891 – 1.09 0.743 422 4246 all phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 0.986 0.937 – 1.04 0.592 1654 16540 all phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.07 1.01 – 1.12 0.0124 1531 15350 all phecode
580.1 Glomerulonephritis Genitourinary 1.07 1 – 1.14 0.0403 1052 10544 all phecode
580.11 Proliferative glomerulonephritis Genitourinary 0.975 0.781 – 1.22 0.823 74 738 all phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.879 0.736 – 1.05 0.155 135 1360 all phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.1 1.03 – 1.18 0.00677 876 8769 all phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.09 0.992 – 1.19 0.0725 468 4697 all phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 0.998 0.875 – 1.14 0.971 246 2460 all phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.01 0.893 – 1.15 0.831 253 2529 all phecode
585 Renal failure Genitourinary 1.02 0.996 – 1.05 0.0983 6967 69751 all phecode
585.1 Acute renal failure Genitourinary 1.02 0.987 – 1.05 0.274 4527 45305 all phecode
585.2 Renal failure NOS Genitourinary 0.994 0.942 – 1.05 0.812 1460 14625 all phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.03 0.992 – 1.07 0.112 2644 26484 all phecode
585.31 Renal dialysis Genitourinary 1.06 0.964 – 1.15 0.244 496 4955 all phecode
586 Other disorders of the kidney and ureters Genitourinary 0.989 0.954 – 1.02 0.528 3355 33580 all phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 0.958 0.83 – 1.1 0.552 208 2089 all phecode
586.11 Small kidney Genitourinary 0.966 0.828 – 1.13 0.661 179 1799 all phecode
586.2 Cyst of kidney, acquired Genitourinary 1.02 0.965 – 1.08 0.448 1257 12582 all phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 1.02 0.811 – 1.27 0.89 80 799 all phecode
586.4 Stricture/obstruction of ureter Genitourinary 0.995 0.929 – 1.07 0.876 910 9122 all phecode
587 Kidney replaced by transpant Genitourinary 1.03 0.93 – 1.15 0.527 368 3683 all phecode
588 Disorders resulting from impaired renal function Genitourinary 1.17 0.959 – 1.44 0.119 99 990 all phecode
589 Abnormal results of function study of kidney Genitourinary 0.979 0.812 – 1.18 0.825 116 1158 all phecode
590 Pyelonephritis Genitourinary 1.03 0.975 – 1.09 0.279 1328 13285 all phecode
591 Urinary tract infection Genitourinary 0.983 0.965 – 1 0.0735 12400 123937 all phecode
592 Cystitis and urethritis Genitourinary 1 0.964 – 1.04 0.941 2966 29661 all phecode
592.1 Cystitis Genitourinary 0.994 0.956 – 1.03 0.74 2904 29035 all phecode
592.11 Acute cystitis Genitourinary 0.979 0.821 – 1.17 0.818 138 1372 all phecode
592.12 Chronic cystitis Genitourinary 1 0.933 – 1.07 1 889 8890 all phecode
592.13 Chronic interstitial cystitis Genitourinary 0.951 0.832 – 1.09 0.461 249 2486 all phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.11 0.951 – 1.29 0.19 165 1662 all phecode
593 Hematuria Genitourinary 0.98 0.964 – 0.996 0.0147 16068 160204 all phecode
594 Urinary calculus Genitourinary 0.959 0.934 – 0.984 0.0015 6376 63761 all phecode
594.1 Calculus of kidney Genitourinary 0.96 0.926 – 0.996 0.0306 3175 31757 all phecode
594.2 Calculus of lower urinary tract Genitourinary 0.903 0.839 – 0.973 0.00747 776 7764 all phecode
594.3 Calculus of ureter Genitourinary 0.971 0.931 – 1.01 0.165 2401 24024 all phecode
594.8 Renal colic Genitourinary 0.973 0.93 – 1.02 0.238 2050 20500 all phecode
595 Hydronephrosis Genitourinary 0.951 0.907 – 0.997 0.0359 1936 19395 all phecode
596 Other disorders of bladder Genitourinary 1.01 0.99 – 1.03 0.333 9771 97778 all phecode
596.1 Bladder neck obstruction Genitourinary 0.975 0.93 – 1.02 0.281 1969 19690 all phecode
596.5 Functional disorders of bladder Genitourinary 1.02 0.966 – 1.07 0.535 1658 16572 all phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.02 0.99 – 1.06 0.178 3913 39135 all phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.02 0.986 – 1.06 0.246 3317 33137 all phecode
597.2 Urinary complications NEC Genitourinary 0.928 0.739 – 1.17 0.523 78 778 all phecode
598 Abnormal findings on examination of urine Genitourinary 1.01 0.974 – 1.04 0.631 3528 35302 all phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.03 0.913 – 1.15 0.667 304 3035 all phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1 0.986 – 1.02 0.921 18428 184311 all phecode
599.1 Urinary obstruction Genitourinary 0.886 0.752 – 1.04 0.145 166 1670 all phecode
599.2 Retention of urine Genitourinary 1.03 1 – 1.05 0.0308 6718 67168 all phecode
599.3 Dysuria Genitourinary 0.984 0.927 – 1.04 0.59 1196 11967 all phecode
599.4 Urinary incontinence Genitourinary 1 0.981 – 1.02 0.819 8748 87477 all phecode
599.5 Frequency of urination and polyuria Genitourinary 1 0.968 – 1.03 0.99 4018 40144 all phecode
599.6 Oliguria and anuria Genitourinary 0.974 0.797 – 1.19 0.796 105 1059 all phecode
599.8 Other symptoms involving urinary system Genitourinary 0.932 0.714 – 1.22 0.607 62 620 all phecode
599.9 Other abnormality of urination Genitourinary 1.02 0.977 – 1.07 0.331 1913 19151 all phecode
600 Hyperplasia of prostate Genitourinary 1.01 0.986 – 1.03 0.595 11093 87892 all phecode
601 Inflammatory diseases of prostate Genitourinary 0.982 0.939 – 1.03 0.424 2081 20818 all phecode
601.1 Prostatitis Genitourinary 0.995 0.945 – 1.05 0.855 1563 15644 all phecode
601.11 Acute prostatitis Genitourinary 0.972 0.854 – 1.11 0.669 234 2358 all phecode
601.12 Chronic prostatitis Genitourinary 0.99 0.925 – 1.06 0.764 910 9089 all phecode
601.3 Orchitis and epididymitis Genitourinary 1.19 0.911 – 1.54 0.205 59 588 all phecode
601.4 Balanoposthitis Genitourinary 0.954 0.844 – 1.08 0.456 287 2864 all phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 0.986 0.877 – 1.11 0.815 303 3019 all phecode
602 Other disorders of prostate Genitourinary 1.03 0.977 – 1.09 0.25 1341 13408 all phecode
603 Other disorders of testis Genitourinary 0.989 0.946 – 1.03 0.637 2150 21512 all phecode
603.1 Hydrocele Genitourinary 0.963 0.91 – 1.02 0.187 1339 13402 all phecode
604 Disorders of penis Genitourinary 1 0.966 – 1.04 0.932 3280 32779 all phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.976 0.938 – 1.02 0.235 2719 27172 all phecode
605 Erectile dysfunction [ED] Genitourinary 1.07 0.948 – 1.2 0.278 278 2800 all phecode
608 Other disorders of male genital organs Genitourinary 1.02 0.98 – 1.06 0.355 2822 28236 all phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.01 0.877 – 1.15 0.93 214 2138 all phecode
609.1 Infertility, male Genitourinary 1.12 0.874 – 1.44 0.37 63 638 all phecode
609.2 Abnormal spermatozoa Genitourinary 1.02 0.873 – 1.18 0.836 169 1698 all phecode
610 Benign mammary dysplasias Genitourinary 1 0.96 – 1.04 0.995 2482 24809 all phecode
610.1 Cystic mastopathy Genitourinary 0.998 0.933 – 1.07 0.958 925 9250 all phecode
610.2 Fibroadenosis of breast Genitourinary 1.09 0.969 – 1.23 0.15 306 3057 all phecode
610.3 Fibrosclerosis of breast Genitourinary 0.939 0.834 – 1.06 0.294 302 3018 all phecode
610.4 Benign neoplasm of breast Genitourinary 0.992 0.939 – 1.05 0.78 1388 13865 all phecode
610.8 Other specified benign mammary dysplasias Genitourinary 0.962 0.889 – 1.04 0.338 696 6954 all phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.06 1.01 – 1.11 0.0308 1574 15731 all phecode
611.1 Abnormal mammogram Genitourinary 1.22 0.936 – 1.58 0.144 57 569 all phecode
611.3 Lump or mass in breast Genitourinary 1.06 1 – 1.11 0.0367 1522 15213 all phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 0.995 0.93 – 1.07 0.895 887 8871 all phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1 0.935 – 1.07 0.948 849 8490 all phecode
612.3 Congenital anomalies of breast Genitourinary 1.03 0.81 – 1.3 0.832 72 719 all phecode
613 Other nonmalignant breast conditions Genitourinary 0.946 0.899 – 0.996 0.0353 1651 16519 all phecode
613.1 Inflammatory disease of breast Genitourinary 0.904 0.835 – 0.978 0.0117 720 7210 all phecode
613.5 Mastodynia Genitourinary 0.875 0.691 – 1.11 0.266 77 768 all phecode
613.7 Other signs and symptoms in breast Genitourinary 1.05 0.967 – 1.13 0.261 702 7013 all phecode
613.8 Other specified disorders of breast Genitourinary 1.01 0.907 – 1.13 0.805 327 3278 all phecode
613.9 Breast disorder NOS Genitourinary 0.943 0.818 – 1.09 0.426 207 2069 all phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.983 0.956 – 1.01 0.208 5711 57118 all phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.985 0.945 – 1.03 0.461 2538 25363 all phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.965 0.899 – 1.04 0.333 830 8308 all phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.14 0.867 – 1.5 0.347 61 608 all phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.959 0.869 – 1.06 0.409 422 4221 all phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.984 0.88 – 1.1 0.774 351 3510 all phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 0.988 0.874 – 1.12 0.844 277 2775 all phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.977 0.938 – 1.02 0.259 2601 26023 all phecode
614.51 Cervicitis and endocervicitis Genitourinary 0.987 0.933 – 1.04 0.655 1318 13189 all phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.02 0.929 – 1.13 0.626 428 4273 all phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.932 0.864 – 1.01 0.0716 755 7574 all phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.05 0.927 – 1.18 0.469 274 2737 all phecode
615 Endometriosis Genitourinary 0.991 0.96 – 1.02 0.604 4029 40284 all phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.11 0.994 – 1.25 0.0633 304 3037 all phecode
618 Genital prolapse Genitourinary 1.02 0.996 – 1.03 0.123 11689 116878 all phecode
618.1 Prolapse of vaginal walls Genitourinary 1.02 0.992 – 1.04 0.183 7392 73940 all phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.01 0.986 – 1.04 0.339 5393 53918 all phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.04 0.95 – 1.14 0.388 512 5125 all phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1 0.924 – 1.08 0.989 680 6794 all phecode
619 Noninflammatory female genital disorders Genitourinary 1 0.981 – 1.03 0.808 8726 87297 all phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.04 0.969 – 1.13 0.253 729 7284 all phecode
619.2 Disorders of uterus, NEC Genitourinary 0.977 0.942 – 1.01 0.206 3324 33273 all phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.03 0.995 – 1.07 0.091 2860 28608 all phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.03 0.982 – 1.08 0.214 1768 17669 all phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.95 0.898 – 1.01 0.0773 1350 13489 all phecode
620 Dysplasia of female genital organs Genitourinary 1.1 0.865 – 1.39 0.449 72 720 all phecode
621 Endometrial hyperplasia Genitourinary 0.975 0.917 – 1.04 0.412 1129 11294 all phecode
622 Polyp of female genital organs Genitourinary 0.997 0.977 – 1.02 0.748 10480 104803 all phecode
622.1 Polyp of corpus uteri Genitourinary 0.987 0.964 – 1.01 0.253 7857 78601 all phecode
622.2 Mucous polyp of cervix Genitourinary 1.01 0.972 – 1.04 0.718 3442 34387 all phecode
623 Hypertrophy of female genital organs Genitourinary 1.03 0.972 – 1.09 0.321 1268 12684 all phecode
624 Symptoms involving female genital tract Genitourinary 0.954 0.887 – 1.03 0.206 797 7961 all phecode
624.1 Dystrophy of female genital tract Genitourinary 0.92 0.805 – 1.05 0.226 237 2365 all phecode
624.2 Atrophy of female genital tract Genitourinary 0.985 0.892 – 1.09 0.759 440 4398 all phecode
624.9 stress incontinence, female Genitourinary 0.999 0.972 – 1.03 0.917 5865 58634 all phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 0.998 0.96 – 1.04 0.929 2876 28740 all phecode
625.1 Dyspareunia Genitourinary 0.999 0.941 – 1.06 0.974 1188 11891 all phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1 0.987 – 1.02 0.669 16168 115018 all phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.01 0.989 – 1.02 0.435 14110 109918 all phecode
626.11 Absent or infrequent menstruation Genitourinary 0.963 0.787 – 1.18 0.716 109 1099 all phecode
626.12 Excessive or frequent menstruation Genitourinary 1.01 0.99 – 1.03 0.305 9727 91749 all phecode
626.13 Irregular menstrual cycle Genitourinary 0.982 0.938 – 1.03 0.455 1985 19829 all phecode
626.14 Irregular menstrual bleeding Genitourinary 1.01 0.979 – 1.05 0.483 3804 38021 all phecode
626.2 Dysmenorrhea Genitourinary 0.946 0.901 – 0.994 0.0287 1778 17767 all phecode
626.4 Premenstrual tension syndromes Genitourinary 1.03 0.884 – 1.21 0.672 159 1587 all phecode
626.8 Infertility, female Genitourinary 0.958 0.906 – 1.01 0.133 1362 13613 all phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.01 0.99 – 1.03 0.323 10392 103948 all phecode
627.1 Postmenopausal bleeding Genitourinary 1 0.982 – 1.03 0.777 9042 90439 all phecode
627.2 Symptomatic menopause Genitourinary 1.14 0.987 – 1.31 0.0749 183 1826 all phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1 0.944 – 1.07 0.879 1111 11115 all phecode
627.4 Premenopausal menorrhagia Genitourinary 1.11 0.988 – 1.24 0.0783 310 3097 all phecode
628 Ovarian cyst Genitourinary 0.99 0.961 – 1.02 0.516 4747 47482 all phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.982 0.953 – 1.01 0.215 5218 36422 all phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 1.01 0.949 – 1.07 0.79 1136 11300 all phecode
634.3 Ectopic pregnancy Pregnancy Complications 1.02 0.909 – 1.14 0.778 331 3305 all phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.994 0.948 – 1.04 0.811 1974 17372 all phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.992 0.924 – 1.07 0.825 866 8614 all phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.996 0.94 – 1.05 0.879 1270 12306 all phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.02 0.978 – 1.07 0.346 2347 19972 all phecode
636.2 Early onset of delivery Pregnancy Complications 1.03 0.947 – 1.12 0.496 617 6144 all phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1.01 0.95 – 1.08 0.724 1082 10766 all phecode
638 Other high-risk pregnancy Pregnancy Complications 0.927 0.724 – 1.19 0.545 70 700 all phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.971 0.912 – 1.03 0.348 1110 11074 all phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1.02 0.909 – 1.15 0.719 307 3058 all phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.868 0.751 – 1 0.0529 215 2149 all phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.935 0.791 – 1.11 0.432 153 1525 all phecode
645 Late pregnancy and failed induction Pregnancy Complications 1 0.944 – 1.06 0.984 1250 12450 all phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.999 0.956 – 1.04 0.957 2228 20847 all phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.993 0.783 – 1.26 0.952 68 679 all phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.06 0.938 – 1.2 0.346 275 2748 all phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.92 0.759 – 1.11 0.394 113 1129 all phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 1.02 0.875 – 1.18 0.828 193 1922 all phecode
650 Normal delivery Pregnancy Complications 0.985 0.94 – 1.03 0.533 1922 18973 all phecode
651 Multiple gestation Pregnancy Complications 0.947 0.846 – 1.06 0.34 346 3454 all phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.973 0.926 – 1.02 0.289 1716 16521 all phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1 0.95 – 1.06 0.895 1401 13649 all phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.28 1.02 – 1.62 0.0364 74 739 all phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.99 0.958 – 1.02 0.547 4306 29454 all phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.05 0.864 – 1.27 0.626 109 1080 all phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.956 0.915 – 1 0.0486 2265 18397 all phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.982 0.897 – 1.07 0.69 532 5316 all phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.979 0.95 – 1.01 0.167 5313 29472 all phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.997 0.956 – 1.04 0.873 2552 21174 all phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.921 0.778 – 1.09 0.338 164 1628 all phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1 0.883 – 1.13 0.992 262 2605 all phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.03 0.79 – 1.35 0.816 63 624 all phecode
679 Complications of in utero procedures Dermatologic 1.08 0.823 – 1.42 0.577 53 530 all phecode
681 Superficial cellulitis and abscess Dermatologic 0.995 0.971 – 1.02 0.657 7200 72225 all phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.926 0.848 – 1.01 0.088 563 5647 all phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.08 0.986 – 1.18 0.0992 520 5208 all phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 0.991 0.964 – 1.02 0.543 5481 55014 all phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 0.993 0.966 – 1.02 0.63 5487 55074 all phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 0.992 0.965 – 1.02 0.59 5444 54643 all phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.07 0.988 – 1.16 0.0938 597 5987 all phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.12 1.06 – 1.18 4.13e-05 1337 13427 all phecode
686.1 Carbuncle and furuncle Dermatologic 1 0.962 – 1.05 0.836 2284 22925 all phecode
686.3 Pilonidal cyst Dermatologic 0.946 0.868 – 1.03 0.208 583 5837 all phecode
686.4 Pyogenic granuloma Dermatologic 0.881 0.788 – 0.986 0.0273 362 3615 all phecode
687 Symptoms affecting skin Dermatologic 1.08 0.994 – 1.18 0.0697 548 5508 all phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 0.991 0.948 – 1.04 0.701 2146 21470 all phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.1 0.974 – 1.24 0.127 283 2839 all phecode
687.3 Changes in skin texture Dermatologic 1.06 0.865 – 1.29 0.588 106 1070 all phecode
687.4 Disturbance of skin sensation Dermatologic 1.02 0.981 – 1.06 0.325 2884 28859 all phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.978 0.952 – 1.01 0.11 5747 57521 all phecode
690 Erythematosquamous dermatosis Dermatologic 0.909 0.712 – 1.16 0.441 71 710 all phecode
690.1 Seborrheic dermatitis Dermatologic 0.895 0.67 – 1.2 0.455 53 530 all phecode
691 Congenital anomalies of skin Dermatologic 0.877 0.718 – 1.07 0.195 120 1199 all phecode
694 Dyschromia and Vitiligo Dermatologic 0.974 0.912 – 1.04 0.438 986 9854 all phecode
694.1 Vitiligo Dermatologic 0.936 0.71 – 1.23 0.636 60 599 all phecode
694.2 Other dyschromia Dermatologic 0.953 0.885 – 1.03 0.202 782 7821 all phecode
694.3 Vascular disorders of skin Dermatologic 1.07 0.888 – 1.3 0.466 117 1170 all phecode
695 Erythematous conditions Dermatologic 0.99 0.948 – 1.03 0.634 2379 23813 all phecode
695.1 Toxic erythema Dermatologic 1.01 0.835 – 1.23 0.882 109 1090 all phecode
695.2 Bullous dermatoses Dermatologic 1.02 0.853 – 1.22 0.845 137 1365 all phecode
695.21 Dermatitis herpetiformis Dermatologic 1.22 0.942 – 1.58 0.133 57 569 all phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.899 0.699 – 1.16 0.404 73 727 all phecode
695.3 Rosacea Dermatologic 1.09 0.974 – 1.23 0.13 309 3097 all phecode
695.4 Lupus (localized and systemic) Dermatologic 0.966 0.872 – 1.07 0.514 411 4114 all phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.825 0.683 – 0.996 0.0453 130 1295 all phecode
695.42 Systemic lupus erythematosus Dermatologic 0.96 0.859 – 1.07 0.477 340 3407 all phecode
695.7 Prurigo and Lichen Dermatologic 0.984 0.914 – 1.06 0.676 775 7760 all phecode
695.8 Other specified erythematous conditions Dermatologic 0.909 0.794 – 1.04 0.169 236 2359 all phecode
695.81 Erythema nodosum Dermatologic 0.773 0.607 – 0.984 0.0364 76 760 all phecode
695.9 Unspecified erythematous condition Dermatologic 1.01 0.919 – 1.11 0.816 467 4672 all phecode
696 Psoriasis and related disorders Dermatologic 0.989 0.947 – 1.03 0.628 2252 22509 all phecode
696.4 Psoriasis Dermatologic 0.992 0.949 – 1.04 0.711 2198 21969 all phecode
696.41 Psoriasis vulgaris Dermatologic 1 0.953 – 1.05 0.927 1680 16796 all phecode
696.42 Psoriatic arthropathy Dermatologic 1.01 0.932 – 1.09 0.848 706 7052 all phecode
697 Sarcoidosis Dermatologic 1.07 0.981 – 1.17 0.126 539 5373 all phecode
698 Pruritus and related conditions Dermatologic 1.03 0.954 – 1.1 0.49 782 7814 all phecode
700 Corns and callosities Dermatologic 0.964 0.855 – 1.09 0.558 291 2904 all phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 0.997 0.967 – 1.03 0.828 4663 46650 all phecode
701.1 Keratoderma, acquired Dermatologic 1.09 0.875 – 1.36 0.436 87 870 all phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1 0.962 – 1.05 0.854 2348 23478 all phecode
701.3 Circumscribed scleroderma Dermatologic 1.02 0.781 – 1.32 0.904 61 610 all phecode
701.4 Keloid scar Dermatologic 0.971 0.843 – 1.12 0.685 216 2159 all phecode
701.5 Abnormal granulation tissue Dermatologic 1.04 0.943 – 1.14 0.459 455 4568 all phecode
701.6 Acquired acanthosis nigricans Dermatologic 0.974 0.795 – 1.19 0.797 102 1019 all phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 1.01 0.979 – 1.04 0.641 5459 54587 all phecode
702.1 Actinic keratosis Dermatologic 0.997 0.957 – 1.04 0.882 2585 25842 all phecode
702.2 Seborrheic keratosis Dermatologic 1.02 0.98 – 1.05 0.387 3078 30772 all phecode
703 Diseases of nail, NOS Dermatologic 1.08 0.973 – 1.21 0.146 354 3539 all phecode
703.1 Ingrowing nail Dermatologic 1.07 1.01 – 1.15 0.0344 966 9660 all phecode
704 Diseases of hair and hair follicles Dermatologic 1.03 1 – 1.06 0.0512 5267 52727 all phecode
704.1 Alopecia Dermatologic 0.953 0.794 – 1.14 0.607 125 1269 all phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.1 0.885 – 1.36 0.398 76 759 all phecode
705 Disorders of sweat glands Dermatologic 0.98 0.855 – 1.12 0.774 228 2287 all phecode
705.3 Hidradenitis Dermatologic 0.942 0.81 – 1.1 0.443 186 1868 all phecode
705.8 Hyperhidrosis Dermatologic 1.09 1 – 1.18 0.0389 591 5919 all phecode
706 Diseases of sebaceous glands Dermatologic 1.03 1.01 – 1.05 0.0112 8317 83195 all phecode
706.1 Acne Dermatologic 1.28 1.02 – 1.61 0.031 78 779 all phecode
706.2 Sebaceous cyst Dermatologic 1.02 0.997 – 1.04 0.0841 8787 87882 all phecode
707 Chronic ulcer of skin Dermatologic 1.03 0.983 – 1.08 0.216 1953 19654 all phecode
707.1 Decubitus ulcer Dermatologic 1.04 0.973 – 1.11 0.242 909 9097 all phecode
709 Diffuse diseases of connective tissue Dermatologic 0.997 0.963 – 1.03 0.874 3432 34317 all phecode
709.2 Sicca syndrome Dermatologic 1.01 0.925 – 1.11 0.775 508 5073 all phecode
709.3 Systemic sclerosis Dermatologic 0.986 0.844 – 1.15 0.861 176 1753 all phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1 0.783 – 1.29 0.972 65 649 all phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 0.989 0.951 – 1.03 0.588 2714 27144 all phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 0.994 0.915 – 1.08 0.894 602 6034 all phecode
710.1 Osteomyelitis Musculoskeletal 0.986 0.903 – 1.08 0.746 556 5574 all phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.02 0.876 – 1.18 0.836 194 1947 all phecode
710.19 Unspecified osteomyelitis Musculoskeletal 0.984 0.888 – 1.09 0.762 398 3997 all phecode
711 Arthropathy associated with infections Musculoskeletal 1.05 0.952 – 1.16 0.33 421 4225 all phecode
711.1 Pyogenic arthritis Musculoskeletal 1.05 0.938 – 1.17 0.409 328 3296 all phecode
712 Infective connective tissue disorders Musculoskeletal 1.21 0.981 – 1.5 0.0744 81 810 all phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.11 0.944 – 1.3 0.212 148 1499 all phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.08 0.85 – 1.37 0.525 65 669 all phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 0.992 0.963 – 1.02 0.609 4832 48320 all phecode
714.1 Rheumatoid arthritis Musculoskeletal 0.986 0.956 – 1.02 0.383 4372 43714 all phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.995 0.946 – 1.05 0.856 1659 16588 all phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.07 0.887 – 1.29 0.481 113 1129 all phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.03 0.953 – 1.12 0.426 618 6177 all phecode
716 Other arthropathies Musculoskeletal 1.01 1 – 1.02 0.0393 37478 265375 all phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.02 0.987 – 1.06 0.221 3505 35090 all phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.01 0.997 – 1.03 0.118 15522 155339 all phecode
716.9 Arthropathy NOS Musculoskeletal 1.01 0.999 – 1.02 0.0771 35944 262308 all phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.02 0.959 – 1.08 0.551 1145 11480 all phecode
720 Spinal stenosis Musculoskeletal 1.03 0.993 – 1.06 0.127 3705 37091 all phecode
721 Spondylosis and allied disorders Musculoskeletal 1.01 0.982 – 1.03 0.666 7832 78318 all phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.02 0.988 – 1.05 0.257 5045 50451 all phecode
721.2 Spondylosis with myelopathy Musculoskeletal 1.02 0.877 – 1.18 0.818 189 1899 all phecode
721.8 Other allied disorders of spine Musculoskeletal 1.01 0.908 – 1.13 0.827 352 3519 all phecode
722 Intervertebral disc disorders Musculoskeletal 1.02 1 – 1.05 0.0272 8978 89848 all phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.03 0.943 – 1.13 0.494 512 5116 all phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.05 1.01 – 1.09 0.0234 2831 28328 all phecode
722.8 Postlaminectomy syndrome Musculoskeletal 0.937 0.728 – 1.21 0.613 67 669 all phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.03 1 – 1.07 0.039 4407 44127 all phecode
723 Other disorders of cervical region Musculoskeletal 1.04 0.953 – 1.14 0.364 517 5173 all phecode
723.1 Torticollis Musculoskeletal 1.03 0.846 – 1.25 0.772 107 1068 all phecode
724 Other and unspecified disorders of back Musculoskeletal 1.04 0.998 – 1.09 0.0619 2052 20514 all phecode
724.1 Disorders of sacrum Musculoskeletal 1 0.907 – 1.11 0.931 403 4024 all phecode
724.2 Disorders of coccyx Musculoskeletal 0.998 0.902 – 1.1 0.962 406 4054 all phecode
724.8 Other symptoms referable to back Musculoskeletal 1.16 0.914 – 1.48 0.22 63 630 all phecode
724.9 Other unspecified back disorders Musculoskeletal 1.05 1 – 1.11 0.0497 1614 16139 all phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 0.993 0.976 – 1.01 0.41 14663 146691 all phecode
726.1 Enthesopathy Musculoskeletal 1 0.98 – 1.02 0.949 9589 95900 all phecode
726.2 Synoviopathy Musculoskeletal 0.934 0.834 – 1.05 0.243 334 3336 all phecode
726.3 Bursitis Musculoskeletal 0.996 0.928 – 1.07 0.903 854 8573 all phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.01 0.984 – 1.03 0.531 7331 73332 all phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.981 0.943 – 1.02 0.334 2737 27406 all phecode
727.2 Bursitis disorders Musculoskeletal 0.941 0.77 – 1.15 0.557 103 1029 all phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1.01 0.975 – 1.05 0.538 3109 31085 all phecode
727.5 Rupture of synovium Musculoskeletal 1.04 0.953 – 1.12 0.407 586 5854 all phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.995 0.891 – 1.11 0.935 353 3527 all phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 1.05 0.885 – 1.24 0.582 143 1429 all phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 1.01 0.974 – 1.04 0.657 3677 36788 all phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.06 0.961 – 1.17 0.243 412 4115 all phecode
728.7 Fasciitis Musculoskeletal 1.01 0.976 – 1.04 0.59 3803 38045 all phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 1.01 0.971 – 1.04 0.767 3477 34788 all phecode
729 Other disorders of soft tissues Musculoskeletal 1.02 0.989 – 1.04 0.257 6014 60309 all phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.03 0.963 – 1.1 0.418 1005 10063 all phecode
729.3 Panniculitis Musculoskeletal 0.894 0.725 – 1.1 0.298 101 1009 all phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.01 0.891 – 1.14 0.895 276 2758 all phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.01 0.887 – 1.14 0.918 261 2609 all phecode
732 Osteochondropathies Musculoskeletal 0.92 0.835 – 1.02 0.0969 467 4679 all phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.845 0.729 – 0.979 0.0252 207 2068 all phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.06 0.806 – 1.39 0.686 57 570 all phecode
733 Other disorders of bone and cartilage Musculoskeletal 1 0.953 – 1.05 0.985 1777 17814 all phecode
733.2 Cyst of bone Musculoskeletal 1.01 0.894 – 1.13 0.933 311 3115 all phecode
733.4 Aseptic necrosis of bone Musculoskeletal 0.994 0.91 – 1.09 0.897 540 5393 all phecode
733.6 Costochondritis Musculoskeletal 1.03 0.864 – 1.23 0.733 128 1276 all phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1 0.943 – 1.06 0.997 1231 12313 all phecode
733.9 Chondromalacia Musculoskeletal 0.863 0.714 – 1.04 0.128 121 1206 all phecode
735 Acquired foot deformities Musculoskeletal 0.995 0.974 – 1.02 0.652 9603 96090 all phecode
735.1 Flat foot Musculoskeletal 0.999 0.861 – 1.16 0.986 189 1910 all phecode
735.2 Acquired toe deformities Musculoskeletal 1.01 0.981 – 1.04 0.53 5070 50712 all phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.04 0.993 – 1.09 0.0962 1929 19324 all phecode
735.23 Hallux rigidus Musculoskeletal 0.974 0.924 – 1.03 0.321 1555 15527 all phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.993 0.968 – 1.02 0.563 6643 66463 all phecode
736 Other acquired deformities of limbs Musculoskeletal 1.03 0.976 – 1.08 0.299 1627 16282 all phecode
736.2 Acquired deformities of finger Musculoskeletal 1.04 0.912 – 1.18 0.574 248 2476 all phecode
737 Curvature of spine Musculoskeletal 1 0.941 – 1.06 0.974 1128 11300 all phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.01 0.943 – 1.07 0.871 1061 10632 all phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.974 0.929 – 1.02 0.286 1904 19058 all phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.963 0.913 – 1.02 0.164 1513 15147 all phecode
739 Contracture of joint Musculoskeletal 0.961 0.876 – 1.05 0.398 488 4884 all phecode
740 Osteoarthrosis Musculoskeletal 1.01 0.996 – 1.02 0.192 27707 231603 all phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.01 0.992 – 1.02 0.345 17412 169419 all phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 0.998 0.976 – 1.02 0.84 8974 89750 all phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.03 0.923 – 1.15 0.611 348 3474 all phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.973 0.894 – 1.06 0.532 598 5969 all phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.01 0.989 – 1.03 0.455 12270 122792 all phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.01 0.978 – 1.05 0.491 3563 35648 all phecode
741.1 Ankylosis of joint Musculoskeletal 0.987 0.804 – 1.21 0.898 102 1019 all phecode
741.2 Stiffness of joint Musculoskeletal 1.03 0.949 – 1.12 0.463 614 6146 all phecode
741.3 Difficulty in walking Musculoskeletal 1.06 0.905 – 1.25 0.464 154 1540 all phecode
741.4 Joint effusions Musculoskeletal 1.04 0.989 – 1.1 0.117 1418 14197 all phecode
741.5 Hemarthrosis Musculoskeletal 1.08 0.89 – 1.31 0.442 110 1100 all phecode
741.6 Villonodular synovitis Musculoskeletal 0.836 0.625 – 1.12 0.228 54 535 all phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.03 0.991 – 1.07 0.137 2843 28441 all phecode
742.1 Loose body in joint Musculoskeletal 1.07 0.955 – 1.19 0.253 333 3337 all phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 0.912 0.735 – 1.13 0.4 95 960 all phecode
742.8 Articular cartilage disorder Musculoskeletal 1.07 0.975 – 1.17 0.152 500 4996 all phecode
742.9 Other derangement of joint Musculoskeletal 1.03 0.985 – 1.08 0.192 1993 19926 all phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.01 0.986 – 1.03 0.446 7563 75729 all phecode
743.1 Osteoporosis Musculoskeletal 1.01 0.98 – 1.03 0.665 6400 64107 all phecode
743.11 Osteoporosis NOS Musculoskeletal 1.01 0.978 – 1.03 0.683 5549 55604 all phecode
743.13 Other specified osteoporosis Musculoskeletal 0.988 0.904 – 1.08 0.798 529 5283 all phecode
743.2 Pathologic fracture Musculoskeletal 1.02 0.929 – 1.11 0.703 516 5179 all phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.02 0.949 – 1.1 0.593 815 8144 all phecode
745 Pain in joint Musculoskeletal 1.01 0.989 – 1.04 0.314 7975 79789 all phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.979 0.941 – 1.02 0.288 2802 28058 all phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.977 0.938 – 1.02 0.266 2628 26323 all phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.954 0.874 – 1.04 0.287 584 5838 all phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 0.993 0.866 – 1.14 0.924 235 2358 all phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 0.99 0.943 – 1.04 0.689 1816 18200 all phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 0.992 0.852 – 1.16 0.923 167 1680 all phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.14 0.865 – 1.51 0.347 51 510 all phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.03 0.916 – 1.16 0.606 303 3029 all phecode
750 Digestive congenital anomalies Congenital Anomalies 1.02 0.942 – 1.1 0.652 686 6870 all phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.05 0.936 – 1.17 0.431 327 3263 all phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.965 0.835 – 1.12 0.634 191 1909 all phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 1.01 0.905 – 1.12 0.878 356 3574 all phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.99 0.865 – 1.13 0.886 225 2256 all phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.934 0.773 – 1.13 0.482 117 1179 all phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.972 0.921 – 1.02 0.29 1527 15286 all phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.941 0.869 – 1.02 0.133 694 6932 all phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.947 0.858 – 1.04 0.271 455 4546 all phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.943 0.82 – 1.09 0.414 222 2217 all phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.01 0.939 – 1.08 0.834 836 8385 all phecode
751.21 Cystic kidney disease Congenital Anomalies 1.06 0.962 – 1.17 0.237 424 4246 all phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.989 0.885 – 1.1 0.84 333 3346 all phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.931 0.83 – 1.04 0.225 328 3307 all phecode
752.1 Neural tube defects Congenital Anomalies 1.02 0.897 – 1.17 0.736 253 2557 all phecode
752.11 Spina bifida Congenital Anomalies 1.01 0.871 – 1.16 0.94 208 2108 all phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.751 0.585 – 0.965 0.0249 78 780 all phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.06 0.887 – 1.27 0.512 127 1270 all phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 1.05 0.837 – 1.33 0.652 76 760 all phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.901 0.739 – 1.1 0.305 109 1099 all phecode
755 Congenital anomalies of limbs Congenital Anomalies 1 0.905 – 1.1 0.996 425 4276 all phecode
755.1 Congenital deformities of feet Congenital Anomalies 1.01 0.874 – 1.16 0.912 208 2086 all phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.927 0.788 – 1.09 0.356 160 1620 all phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.859 0.701 – 1.05 0.143 106 1070 all phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.99 0.909 – 1.08 0.81 587 5872 all phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.961 0.768 – 1.2 0.728 81 810 all phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.998 0.905 – 1.1 0.973 435 4356 all phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.15 0.974 – 1.35 0.1 148 1708 all phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.2 0.936 – 1.55 0.15 60 830 all phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 0.975 0.85 – 1.12 0.724 216 2159 all phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1 0.816 – 1.23 0.996 96 959 all phecode
760 Back pain Symptoms 1.01 0.994 – 1.03 0.167 11126 111353 all phecode
761 Cervicalgia Symptoms 1 0.953 – 1.05 0.991 1791 17901 all phecode
764 Sciatica Symptoms 0.985 0.944 – 1.03 0.467 2372 23732 all phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.07 1 – 1.13 0.035 1172 11738 all phecode
770 Myalgia and myositis unspecified Symptoms 1.13 1.05 – 1.23 0.00208 631 6311 all phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.97 0.904 – 1.04 0.395 870 8687 all phecode
771.1 Swelling of limb Symptoms 1.01 0.983 – 1.04 0.411 4617 46330 all phecode
772 Symptoms of the muscles Symptoms 1.05 0.966 – 1.13 0.264 659 6581 all phecode
773 Pain in limb Symptoms 1 0.974 – 1.03 0.982 6209 62203 all phecode
780 Hypothermia/Chills Symptoms 0.976 0.835 – 1.14 0.76 171 1719 all phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.05 1 – 1.1 0.0414 1870 18715 all phecode
782.3 Edema Symptoms 1.04 0.987 – 1.09 0.144 1642 16450 all phecode
782.6 Pallor and flushing Symptoms 0.931 0.793 – 1.09 0.386 175 1748 all phecode
783 Fever of unknown origin Symptoms 1.01 0.978 – 1.04 0.522 3911 39105 all phecode
785 Abdominal pain Symptoms 1.01 0.995 – 1.02 0.28 40080 301686 all phecode
788 Syncope and collapse Symptoms 1 0.98 – 1.02 0.92 9069 90813 all phecode
789 Nausea and vomiting Symptoms 1 0.981 – 1.02 0.979 11577 115807 all phecode
790 Nonspecific findings on examination of blood Symptoms 1.11 0.944 – 1.31 0.208 150 1500 all phecode
790.1 Elevated sedimentation rate Symptoms 0.899 0.711 – 1.14 0.372 84 840 all phecode
790.6 Other abnormal blood chemistry Symptoms 1 0.979 – 1.03 0.71 6357 63635 all phecode
791 Gangrene Symptoms 1.09 0.999 – 1.18 0.0539 549 5501 all phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.9 0.728 – 1.11 0.332 98 966 all phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.05 0.888 – 1.25 0.551 134 1340 all phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.04 0.958 – 1.14 0.323 565 5647 all phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.958 0.793 – 1.16 0.656 120 1198 all phecode
797 Shock Symptoms 1.11 0.95 – 1.3 0.185 156 1559 all phecode
797.1 Cardiogenic shock Symptoms 1.11 0.915 – 1.36 0.283 102 1020 all phecode
798 Malaise and fatigue Symptoms 0.997 0.962 – 1.03 0.865 3408 34103 all phecode
798.1 Chronic fatigue syndrome Symptoms 1.01 0.924 – 1.09 0.898 591 5913 all phecode
800 Fracture of lower limb Injuries & Poisonings 1.01 0.985 – 1.03 0.469 7035 70329 all phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.01 0.961 – 1.06 0.716 1815 18152 all phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.11 0.952 – 1.29 0.187 170 1693 all phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.05 1 – 1.09 0.0367 2158 21577 all phecode
800.4 Fracture of patella Injuries & Poisonings 1.07 0.998 – 1.16 0.057 766 7661 all phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.01 0.968 – 1.06 0.63 2205 22041 all phecode
801.1 Fracture of foot Injuries & Poisonings 1.05 1 – 1.1 0.0463 1835 18346 all phecode
802 Fracture of pelvis Injuries & Poisonings 1.02 0.943 – 1.1 0.642 718 7185 all phecode
803 Fracture of upper limb Injuries & Poisonings 1.02 1 – 1.05 0.0344 8288 82880 all phecode
803.1 Fracture of humerus Injuries & Poisonings 1.03 0.984 – 1.09 0.187 1691 16883 all phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.02 0.996 – 1.05 0.0963 5215 52171 all phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.05 0.996 – 1.11 0.0727 1518 15186 all phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.993 0.958 – 1.03 0.692 3339 33384 all phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.03 0.972 – 1.09 0.333 1358 13565 all phecode
807 Fracture of ribs Injuries & Poisonings 0.975 0.906 – 1.05 0.494 776 7752 all phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.03 0.972 – 1.09 0.33 1300 12998 all phecode
817 Concussion Injuries & Poisonings 1.11 0.973 – 1.26 0.123 243 2428 all phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.05 0.956 – 1.14 0.326 522 5213 all phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.02 0.984 – 1.06 0.266 2957 29596 all phecode
823 Torus fracture Injuries & Poisonings 1.07 1.02 – 1.12 0.00943 1673 16710 all phecode
830 Dislocation Injuries & Poisonings 0.999 0.956 – 1.05 0.979 2088 20872 all phecode
835 Internal derangement of knee Injuries & Poisonings 1.02 0.999 – 1.03 0.0737 15221 152247 all phecode
836 Traumatic arthropathy Injuries & Poisonings 1.05 0.961 – 1.15 0.277 526 5267 all phecode
840 Sprains and strains Injuries & Poisonings 0.935 0.85 – 1.03 0.171 470 4697 all phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.03 0.997 – 1.06 0.0763 5259 52626 all phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.987 0.835 – 1.17 0.883 157 1567 all phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.02 0.928 – 1.12 0.708 501 5010 all phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.01 0.961 – 1.06 0.728 1826 18238 all phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.987 0.931 – 1.05 0.672 1241 12418 all phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.976 0.941 – 1.01 0.194 3158 31607 all phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.01 0.974 – 1.05 0.612 3259 32599 all phecode
860 Bone marrow or stem cell transplant Neoplasms 1.16 0.918 – 1.47 0.211 68 680 all phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.02 0.983 – 1.05 0.334 3502 35062 all phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.963 0.85 – 1.09 0.557 272 2713 all phecode
870.2 Open wound of ear Injuries & Poisonings 0.998 0.86 – 1.16 0.976 196 1949 all phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.03 0.994 – 1.07 0.103 2904 29085 all phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.05 0.917 – 1.21 0.471 220 2199 all phecode
870.6 Open wound of neck Injuries & Poisonings 1.01 0.796 – 1.27 0.955 68 678 all phecode
871 Open wounds of extremities Injuries & Poisonings 1.02 0.989 – 1.05 0.208 4063 40648 all phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.963 0.725 – 1.28 0.795 53 530 all phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.07 0.865 – 1.33 0.52 91 900 all phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.03 0.891 – 1.2 0.665 178 1785 all phecode
872 Traumatic amputation Injuries & Poisonings 1.02 0.925 – 1.12 0.746 475 4742 all phecode
873 Broken tooth Injuries & Poisonings 1.14 1 – 1.3 0.0508 229 2289 all phecode
874 Complication of amputation stump Injuries & Poisonings 1.14 0.982 – 1.33 0.0857 169 1710 all phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.23 1.05 – 1.45 0.0105 157 1567 all phecode
907 Injuries to the nervous system Injuries & Poisonings 1.01 0.951 – 1.06 0.846 1314 13140 all phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.02 0.986 – 1.05 0.285 4260 42663 all phecode
916 Contusion Injuries & Poisonings 0.993 0.941 – 1.05 0.803 1450 14506 all phecode
930 Allergic reaction to food Injuries & Poisonings 0.908 0.777 – 1.06 0.224 179 1807 all phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.07 0.971 – 1.19 0.167 389 3899 all phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 1 0.884 – 1.14 0.963 252 2530 all phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.01 0.968 – 1.06 0.582 2094 20961 all phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.13 0.984 – 1.29 0.0831 225 2249 all phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.885 0.722 – 1.08 0.238 104 1038 all phecode
946 Anaphylactic shock NOS Injuries & Poisonings 0.97 0.887 – 1.06 0.502 550 5509 all phecode
947 Urticaria Injuries & Poisonings 1.09 0.984 – 1.21 0.0986 371 3707 all phecode
949 Allergies, other Injuries & Poisonings 0.927 0.835 – 1.03 0.153 397 3989 all phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.977 0.883 – 1.08 0.647 423 4224 all phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.949 0.836 – 1.08 0.418 269 2698 all phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.07 0.981 – 1.18 0.122 491 4926 all phecode
958.1 Postoperative shock Injuries & Poisonings 1.02 0.779 – 1.34 0.882 55 555 all phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.912 0.713 – 1.17 0.465 74 740 all phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.01 0.991 – 1.02 0.427 18100 181147 all phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.01 0.991 – 1.02 0.376 15846 158623 all phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.01 0.915 – 1.12 0.816 420 4195 all phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 0.991 0.924 – 1.06 0.8 869 8703 all phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.05 0.941 – 1.16 0.411 371 3707 all phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.04 0.931 – 1.15 0.52 364 3638 all phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.999 0.87 – 1.15 0.992 223 2228 all phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.07 0.953 – 1.2 0.25 282 2830 all phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.1 0.975 – 1.24 0.123 276 2770 all phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1 0.977 – 1.03 0.853 6082 60875 all phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.01 0.953 – 1.08 0.693 1144 11447 all phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.05 0.955 – 1.15 0.319 476 4767 all phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.922 0.831 – 1.02 0.123 403 4045 all phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.04 0.95 – 1.14 0.394 512 5123 all phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.05 0.967 – 1.15 0.239 583 5843 all phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 0.999 0.953 – 1.05 0.96 1950 19519 all phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.04 0.895 – 1.2 0.627 190 1908 all phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.01 0.887 – 1.14 0.937 271 2717 all phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.955 0.766 – 1.19 0.678 84 849 all phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.15 0.944 – 1.4 0.168 108 1080 all phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.05 0.86 – 1.28 0.633 101 1018 all phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.931 0.72 – 1.2 0.588 64 640 all phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1 0.761 – 1.32 0.988 58 580 all phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.976 0.854 – 1.12 0.727 234 2337 all phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 0.968 0.896 – 1.05 0.409 698 6966 all phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.944 0.817 – 1.09 0.436 200 1999 all phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 0.957 0.742 – 1.23 0.736 62 620 all phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.02 0.84 – 1.24 0.831 105 1049 all phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.903 0.741 – 1.1 0.315 111 1128 all phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.914 0.729 – 1.15 0.436 89 890 all phecode
990 Effects radiation NOS Injuries & Poisonings 0.991 0.955 – 1.03 0.614 3113 31140 all phecode
994 Sepsis and SIRS Injuries & Poisonings 0.992 0.955 – 1.03 0.663 3028 30268 all phecode
994.2 Sepsis Injuries & Poisonings 0.992 0.955 – 1.03 0.663 3028 30268 all phecode
008 Intestinal infection Infectious Diseases 1.02 0.993 – 1.05 0.142 5538 63928 exclusion phecode
008.5 Bacterial enteritis Infectious Diseases 1.03 0.979 – 1.08 0.269 1663 19453 exclusion phecode
008.52 Intestinal infection due to C. difficile Infectious Diseases 1.07 0.955 – 1.19 0.254 316 4512 exclusion phecode
008.6 Viral Enteritis Infectious Diseases 1.01 0.921 – 1.1 0.902 514 6251 exclusion phecode
008.7 Intestinal infection due to protozoa Infectious Diseases 0.937 0.677 – 1.3 0.695 32 412 exclusion phecode
010 Tuberculosis Infectious Diseases 1.02 0.84 – 1.25 0.81 100 1154 exclusion phecode
038 Septicemia Infectious Diseases 1.02 0.974 – 1.06 0.431 2126 29197 exclusion phecode
038.1 Gram negative septicemia Infectious Diseases 1.04 0.941 – 1.15 0.457 415 5900 exclusion phecode
038.2 Gram positive septicemia Infectious Diseases 1.05 0.924 – 1.2 0.439 227 3457 exclusion phecode
041 Bacterial infection NOS Infectious Diseases 1.04 1.01 – 1.06 0.00292 6955 85937 exclusion phecode
041.1 Staphylococcus infections Infectious Diseases 1.11 1.06 – 1.17 1.29e-05 1679 22196 exclusion phecode
041.2 Streptococcus infection Infectious Diseases 1.02 0.952 – 1.08 0.637 976 11987 exclusion phecode
041.4 E. coli Infectious Diseases 1.04 0.992 – 1.1 0.0987 1520 19569 exclusion phecode
053 Herpes zoster Infectious Diseases 0.978 0.853 – 1.12 0.748 225 2821 exclusion phecode
053.1 Herpes zoster with nervous system complications Infectious Diseases 0.759 0.579 – 0.996 0.0467 57 644 exclusion phecode
054 Herpes simplex Infectious Diseases 0.975 0.821 – 1.16 0.767 141 1606 exclusion phecode
070 Viral hepatitis Infectious Diseases 1.09 0.975 – 1.21 0.131 323 4477 exclusion phecode
070.1 Viral hepatitis A Infectious Diseases 1.03 0.772 – 1.37 0.846 48 549 exclusion phecode
070.2 Viral hepatitis B Infectious Diseases 1.15 0.925 – 1.43 0.206 73 968 exclusion phecode
070.3 Viral hepatitis C Infectious Diseases 1.14 0.964 – 1.36 0.123 132 2012 exclusion phecode
070.4 Chronic hepatitis Infectious Diseases 1.04 0.875 – 1.23 0.666 140 2057 exclusion phecode
070.9 Hepatitis NOS Infectious Diseases 1.07 0.94 – 1.22 0.295 224 3107 exclusion phecode
071 Human immunodeficiency virus [HIV] disease Infectious Diseases 1.1 0.882 – 1.38 0.385 73 1099 exclusion phecode
071.1 HIV infection, symptomatic Infectious Diseases 1.09 0.854 – 1.4 0.478 59 878 exclusion phecode
078 Viral warts & HPV Infectious Diseases 1 0.93 – 1.08 0.913 706 7578 exclusion phecode
079 Viral infection Infectious Diseases 0.989 0.943 – 1.04 0.645 1923 21181 exclusion phecode
079.1 Varicella infection Infectious Diseases 1.02 0.769 – 1.36 0.88 46 518 exclusion phecode
080 Postoperative infection Infectious Diseases 1.03 0.987 – 1.07 0.187 2675 32311 exclusion phecode
081
Infection/inflammation of internal prosthetic
Infection/inflammation of internal prosthetic device; implant; and graft
 Infectious Diseases 1.06 1.01 – 1.12 0.0228 1363 17494 exclusion phecode
090
Sexually transmitted infections (not HIV or
Sexually transmitted infections (not HIV or hepatitis)
 Infectious Diseases 0.986 0.723 – 1.34 0.929 45 535 exclusion phecode
1000 Burns Injuries & Poisonings 1 0.904 – 1.11 0.947 381 4263 exclusion phecode
1001 Foreign body injury Injuries & Poisonings 1.07 1 – 1.15 0.0432 822 8739 exclusion phecode
1002
Symptoms concerning nutrition, metabolism, and
Symptoms concerning nutrition, metabolism, and development
 Injuries & Poisonings 1.03 0.993 – 1.06 0.115 3520 39155 exclusion phecode
1004
Other signs and symptoms involving emotional
Other signs and symptoms involving emotional state
 Injuries & Poisonings 1.1 0.948 – 1.27 0.216 191 2193 exclusion phecode
1005 Other symptoms Injuries & Poisonings 1.01 0.939 – 1.08 0.855 863 10313 exclusion phecode
1006 Crushing injury Injuries & Poisonings 1.03 0.889 – 1.2 0.659 176 1821 exclusion phecode
1007 Injury to blood vessels Injuries & Poisonings 0.998 0.863 – 1.15 0.978 178 1913 exclusion phecode
1008 Crushing or internal injury to organs Injuries & Poisonings 1 0.927 – 1.08 0.99 707 7313 exclusion phecode
1009 Injury, NOS Injuries & Poisonings 1.03 0.999 – 1.05 0.0583 5883 62296 exclusion phecode
1010 Other tests Injuries & Poisonings 0.998 0.966 – 1.03 0.908 3788 42750 exclusion phecode
1011 Complications of surgical and medical procedures Injuries & Poisonings 1.01 0.988 – 1.04 0.29 5585 64404 exclusion phecode
1012 Late effect Injuries & Poisonings 1.1 0.873 – 1.39 0.419 76 764 exclusion phecode
1013 Asphyxia and hypoxemia Injuries & Poisonings 1.07 0.928 – 1.23 0.35 199 2244 exclusion phecode
1014 Effects of heat, cold and air pressure Injuries & Poisonings 1.05 0.792 – 1.39 0.743 53 489 exclusion phecode
1015 Effects of other external causes Injuries & Poisonings 0.998 0.959 – 1.04 0.91 2671 31277 exclusion phecode
1019
Other ill-defined and unknown causes of
Other ill-defined and unknown causes of morbidity and mortality
 Injuries & Poisonings 1.01 0.993 – 1.03 0.19 10738 116961 exclusion phecode
110 Dermatophytosis / Dermatomycosis Infectious Diseases 1.06 0.902 – 1.24 0.497 161 1992 exclusion phecode
110.1 Dermatophytosis Infectious Diseases 1.06 0.902 – 1.24 0.486 157 1957 exclusion phecode
110.11 Dermatophytosis of nail Infectious Diseases 0.999 0.742 – 1.34 0.993 47 532 exclusion phecode
110.12 Althete's foot Infectious Diseases 1.01 0.806 – 1.25 0.962 77 994 exclusion phecode
112 Candidiasis Infectious Diseases 0.997 0.942 – 1.06 0.924 1280 15203 exclusion phecode
117 Mycoses Infectious Diseases 1.15 0.979 – 1.36 0.0881 142 1917 exclusion phecode
117.4 Aspergillosis Infectious Diseases 1.11 0.901 – 1.38 0.32 85 1129 exclusion phecode
130 Spirochetal infection Infectious Diseases 1.02 0.783 – 1.34 0.87 54 603 exclusion phecode
133 Arthropod-borne diseases Infectious Diseases 1.09 0.812 – 1.47 0.565 44 522 exclusion phecode
134 Helminthiases Infectious Diseases 1.05 0.853 – 1.31 0.623 85 996 exclusion phecode
134.1 Intestinal helminthiases Infectious Diseases 1.05 0.827 – 1.32 0.709 70 838 exclusion phecode
136 Other infectious and parasitic diseases Infectious Diseases 1.14 0.957 – 1.37 0.139 124 1464 exclusion phecode
145 Cancer of mouth Neoplasms 0.952 0.862 – 1.05 0.33 440 4516 exclusion phecode
145.2 Cancer of tongue Neoplasms 0.889 0.77 – 1.03 0.107 217 2145 exclusion phecode
145.3 Cancer of major salivary glands Neoplasms 1.2 0.943 – 1.53 0.138 68 791 exclusion phecode
145.5 Cancer of the mouth floor Neoplasms 0.861 0.613 – 1.21 0.39 37 369 exclusion phecode
149 Cancer of larynx, pharynx, nasal cavities Neoplasms 0.886 0.797 – 0.985 0.0251 392 4321 exclusion phecode
149.1 Cancer of oropharynx Neoplasms 0.854 0.728 – 1 0.0538 170 1800 exclusion phecode
149.4 Cancer of larynx Neoplasms 0.918 0.774 – 1.09 0.325 140 1718 exclusion phecode
149.9 Cancer of of nasal cavities Neoplasms 0.832 0.602 – 1.15 0.268 40 382 exclusion phecode
150 Cancer of esophagus Neoplasms 0.917 0.831 – 1.01 0.0818 441 4965 exclusion phecode
151 Cancer of stomach Neoplasms 1.02 0.916 – 1.14 0.68 331 3675 exclusion phecode
153 Colorectal cancer Neoplasms 1.01 0.977 – 1.05 0.46 2982 31087 exclusion phecode
153.2 Colon cancer Neoplasms 1.03 0.98 – 1.07 0.278 2015 20964 exclusion phecode
153.3
Malignant neoplasm of rectum, rectosigmoid
Malignant neoplasm of rectum, rectosigmoid junction, and anus
 Neoplasms 0.998 0.946 – 1.05 0.946 1419 14778 exclusion phecode
155 Cancer of liver and intrahepatic bile duct Neoplasms 1.02 0.891 – 1.16 0.785 220 2702 exclusion phecode
155.1 Malignant neoplasm of liver, primary Neoplasms 1.03 0.816 – 1.3 0.796 69 1024 exclusion phecode
157 Pancreatic cancer Neoplasms 0.977 0.883 – 1.08 0.66 398 4402 exclusion phecode
158
Neoplasm of unspecified nature of digestive
Neoplasm of unspecified nature of digestive system
 Neoplasms 1.01 0.931 – 1.09 0.868 686 7382 exclusion phecode
159
Malignant neoplasm of other and ill-defined
Malignant neoplasm of other and ill-defined sites within the digestive organs and peritoneum
 Neoplasms 0.984 0.951 – 1.02 0.366 3553 37731 exclusion phecode
159.2
Malignant neoplasm of small intestine
Malignant neoplasm of small intestine, including duodenum
 Neoplasms 1.04 0.872 – 1.24 0.674 130 1326 exclusion phecode
159.3
Malignant neoplasm of gallbladder and
Malignant neoplasm of gallbladder and extrahepatic bile ducts
 Neoplasms 0.894 0.747 – 1.07 0.225 131 1394 exclusion phecode
159.4
Malignant neoplasm of retroperitoneum and
Malignant neoplasm of retroperitoneum and peritoneum
 Neoplasms 1.02 0.853 – 1.23 0.797 122 1346 exclusion phecode
164 Cancer of intrathoracic organs Neoplasms 1.01 0.736 – 1.38 0.96 41 409 exclusion phecode
165 Cancer within the respiratory system Neoplasms 0.986 0.937 – 1.04 0.581 1593 18688 exclusion phecode
165.1 Cancer of bronchus; lung Neoplasms 1.04 0.98 – 1.1 0.203 1233 14797 exclusion phecode
170 Cancer of bone and connective tissue Neoplasms 1.09 0.965 – 1.23 0.167 295 3027 exclusion phecode
170.1 Bone cancer Neoplasms 1.2 0.966 – 1.48 0.101 84 899 exclusion phecode
170.2 Cancer of connective tissue Neoplasms 1.05 0.915 – 1.21 0.475 225 2294 exclusion phecode
172 Skin cancer Neoplasms 0.987 0.966 – 1.01 0.237 9327 92779 exclusion phecode
172.1 Melanomas of skin, dx or hx Neoplasms 0.948 0.904 – 0.994 0.0283 1928 19087 exclusion phecode
172.11 Melanomas of skin Neoplasms 0.946 0.902 – 0.992 0.0211 1951 19315 exclusion phecode
172.2 Other non-epithelial cancer of skin Neoplasms 0.992 0.969 – 1.02 0.505 7542 74823 exclusion phecode
172.3 Carcinoma in situ of skin Neoplasms 1.09 0.985 – 1.2 0.0972 406 4415 exclusion phecode
173 Neoplasm of uncertain behavior of skin Neoplasms 0.923 0.769 – 1.11 0.389 128 1321 exclusion phecode
174 Breast cancer Neoplasms 1 0.983 – 1.03 0.717 9487 97258 exclusion phecode
174.1 Breast cancer [female] Neoplasms 1 0.984 – 1.03 0.664 9353 95789 exclusion phecode
174.11 Malignant neoplasm of female breast Neoplasms 1 0.978 – 1.02 0.968 8789 90219 exclusion phecode
174.3 Neoplasm of uncertain behavior of breast Neoplasms 0.945 0.766 – 1.17 0.597 93 905 exclusion phecode
175 Acquired absence of breast Neoplasms 0.993 0.946 – 1.04 0.784 1768 18613 exclusion phecode
180 Cervical cancer and dysplasia Neoplasms 0.956 0.91 – 1.01 0.0794 1779 18031 exclusion phecode
180.1 Cervical cancer Neoplasms 0.999 0.869 – 1.15 0.99 214 2176 exclusion phecode
180.3
Cervical intraepithelial neoplasia [CIN]
Cervical intraepithelial neoplasia [CIN] [Cervical dysplasia]
 Neoplasms 0.942 0.895 – 0.992 0.0227 1703 17213 exclusion phecode
182 Malignant neoplasm of uterus Neoplasms 0.975 0.908 – 1.05 0.482 847 9520 exclusion phecode
184 Cancer of other female genital organs Neoplasms 0.978 0.916 – 1.04 0.506 1010 10505 exclusion phecode
184.1
Malignant neoplasm of ovary and other uterine
Malignant neoplasm of ovary and other uterine adnexa
 Neoplasms 0.972 0.899 – 1.05 0.466 715 7284 exclusion phecode
184.11 Malignant neoplasm of ovary Neoplasms 0.966 0.893 – 1.05 0.394 693 7046 exclusion phecode
184.2
Cancer of other female genital organs
Cancer of other female genital organs (excluding uterus and ovary)
 Neoplasms 0.924 0.802 – 1.07 0.279 219 2371 exclusion phecode
185 Cancer of prostate Neoplasms 1.02 0.99 – 1.06 0.175 3690 35865 exclusion phecode
187 Cancer of other male genital organs Neoplasms 1.06 0.949 – 1.19 0.284 304 3153 exclusion phecode
187.1
Malignant neoplasm of unspecified male genital
Malignant neoplasm of unspecified male genital organ
 Neoplasms 1.49 1.1 – 2.02 0.0103 40 438 exclusion phecode
187.2 Malignant neoplasm of testis Neoplasms 1.02 0.881 – 1.17 0.828 199 2112 exclusion phecode
187.8
Neoplasm of uncertain behavior of male genital
Neoplasm of uncertain behavior of male genital organs
 Neoplasms 0.936 0.742 – 1.18 0.574 75 735 exclusion phecode
189
Cancer of urinary organs (incl. kidney and
Cancer of urinary organs (incl. kidney and bladder)
 Neoplasms 1.02 0.975 – 1.06 0.402 2136 27012 exclusion phecode
189.1 Cancer of kidney and renal pelvis Neoplasms 1.03 0.936 – 1.14 0.525 403 7221 exclusion phecode
189.11 Malignant neoplasm of kidney, except pelvis Neoplasms 1.03 0.931 – 1.14 0.579 383 6951 exclusion phecode
189.12 Malignant neoplasm of renal pelvis Neoplasms 1.02 0.707 – 1.46 0.936 31 434 exclusion phecode
189.2 Cancer of bladder Neoplasms 1.01 0.954 – 1.07 0.779 1356 15398 exclusion phecode
189.21 Malignant neoplasm of bladder Neoplasms 0.999 0.942 – 1.06 0.97 1195 13676 exclusion phecode
189.4 Malignant neoplasm of other urinary organs Neoplasms 0.944 0.729 – 1.22 0.662 58 938 exclusion phecode
190 Cancer of eye Neoplasms 0.816 0.675 – 0.987 0.0359 122 1233 exclusion phecode
191
Manlignant and unknown neoplasms of brain and
Manlignant and unknown neoplasms of brain and nervous system
 Neoplasms 0.975 0.887 – 1.07 0.596 471 4848 exclusion phecode
191.1 Cancer of brain and nervous system Neoplasms 0.995 0.897 – 1.1 0.931 389 3944 exclusion phecode
191.11 Cancer of brain Neoplasms 0.993 0.892 – 1.11 0.898 362 3669 exclusion phecode
193 Thyroid cancer Neoplasms 1.12 0.983 – 1.27 0.0911 234 2652 exclusion phecode
194 Cancer of other endocrine glands Neoplasms 0.938 0.725 – 1.21 0.629 58 701 exclusion phecode
195 Cancer, suspected or other Neoplasms 0.985 0.966 – 1 0.122 11114 116438 exclusion phecode
195.1 Malignant neoplasm, other Neoplasms 0.983 0.964 – 1 0.0924 10621 111911 exclusion phecode
197 Chemotherapy Neoplasms 1.01 0.993 – 1.03 0.238 14014 156042 exclusion phecode
198 Secondary malignant neoplasm Neoplasms 1.01 0.983 – 1.04 0.494 6170 67750 exclusion phecode
198.1 Secondary malignancy of lymph nodes Neoplasms 1.01 0.975 – 1.04 0.615 3642 38998 exclusion phecode
198.2 Secondary malignancy of respiratory organs Neoplasms 0.993 0.94 – 1.05 0.806 1380 15988 exclusion phecode
198.3
Secondary malignant neoplasm of digestive
Secondary malignant neoplasm of digestive systems
 Neoplasms 1.02 0.958 – 1.09 0.531 1009 11039 exclusion phecode
198.4 Secondary malignant neoplasm of liver Neoplasms 1.03 0.976 – 1.08 0.311 1657 18449 exclusion phecode
198.5 Secondary malignancy of brain/spine Neoplasms 0.982 0.899 – 1.07 0.697 527 6027 exclusion phecode
198.6 Secondary malignancy of bone Neoplasms 1.05 0.988 – 1.11 0.123 1291 14889 exclusion phecode
198.7 Secondary malignant neoplasm of skin Neoplasms 0.847 0.7 – 1.02 0.0864 119 1353 exclusion phecode
199 Neoplasm of uncertain behavior Neoplasms 1.02 0.95 – 1.09 0.606 841 10306 exclusion phecode
199.4 Neurofibromatosis Neoplasms 1.03 0.751 – 1.42 0.847 39 706 exclusion phecode
200 Myeloproliferative disease Neoplasms 1.16 1.06 – 1.26 0.00153 480 6747 exclusion phecode
200.1 Polycythemia vera Neoplasms 1.19 1.03 – 1.39 0.0226 162 2584 exclusion phecode
201 Hodgkin's disease Neoplasms 1 0.853 – 1.18 0.982 160 1976 exclusion phecode
202 Cancer of other lymphoid, histiocytic tissue Neoplasms 1.03 0.978 – 1.09 0.235 1288 15846 exclusion phecode
202.2 Non-Hodgkins lymphoma Neoplasms 1.04 0.981 – 1.11 0.175 1012 12512 exclusion phecode
202.21 Nodular lymphoma Neoplasms 1.26 1.1 – 1.43 0.000738 220 2507 exclusion phecode
202.24 Large cell lymphoma Neoplasms 1.06 0.949 – 1.18 0.312 328 4022 exclusion phecode
204 Leukemia Neoplasms 1.02 0.958 – 1.1 0.483 926 11320 exclusion phecode
204.1 Lymphoid leukemia Neoplasms 0.992 0.885 – 1.11 0.893 317 3872 exclusion phecode
204.11 Lymphoid leukemia, acute Neoplasms 1.02 0.712 – 1.45 0.923 34 413 exclusion phecode
204.12 Lymphoid leukemia, chronic Neoplasms 0.999 0.883 – 1.13 0.989 270 3393 exclusion phecode
204.2 Myeloid leukemia Neoplasms 1.06 0.937 – 1.19 0.365 271 3228 exclusion phecode
204.21 Myeloid leukemia, acute Neoplasms 1.11 0.96 – 1.28 0.159 182 2296 exclusion phecode
204.22 Myeloid leukemia, chronic Neoplasms 1.03 0.841 – 1.26 0.784 103 1010 exclusion phecode
204.4 Multiple myeloma Neoplasms 0.996 0.883 – 1.12 0.944 287 3744 exclusion phecode
208 Benign neoplasm of colon Neoplasms 1.01 0.989 – 1.03 0.445 12795 134394 exclusion phecode
210 Benign neoplasm of lip, oral cavity, and pharynx Neoplasms 1 0.928 – 1.09 0.926 681 7213 exclusion phecode
211
Benign neoplasm of other parts of digestive
Benign neoplasm of other parts of digestive system
 Neoplasms 1.06 1.02 – 1.09 0.00168 3571 37441 exclusion phecode
212
Benign neoplasm of respiratory and
Benign neoplasm of respiratory and intrathoracic organs
 Neoplasms 0.947 0.826 – 1.09 0.43 234 2505 exclusion phecode
213 Benign neoplasm of bone and articular cartilage Neoplasms 1.05 0.921 – 1.2 0.453 244 2393 exclusion phecode
214 Lipoma Neoplasms 1.02 0.988 – 1.05 0.226 4392 45251 exclusion phecode
214.1 Lipoma of skin and subcutaneous tissue Neoplasms 1.02 0.981 – 1.05 0.353 3277 33835 exclusion phecode
215
Other benign neoplasm of connective and other
Other benign neoplasm of connective and other soft tissue
 Neoplasms 1.08 1.01 – 1.16 0.0276 820 8233 exclusion phecode
216 Benign neoplasm of skin Neoplasms 1.01 0.983 – 1.04 0.477 5724 57581 exclusion phecode
217 Vascular hamartomas and non-neoplastic nevi Neoplasms 1.04 0.943 – 1.14 0.438 435 4529 exclusion phecode
217.1 Nevus, non-neoplastic Neoplasms 1.03 0.936 – 1.14 0.513 409 4246 exclusion phecode
218 Benign neoplasm of uterus Neoplasms 0.997 0.974 – 1.02 0.784 8074 81251 exclusion phecode
218.1 Uterine leiomyoma Neoplasms 0.995 0.972 – 1.02 0.648 8240 82633 exclusion phecode
218.2 Other benign neoplasm of uterus Neoplasms 0.974 0.86 – 1.1 0.678 269 2832 exclusion phecode
220 Benign neoplasm of ovary Neoplasms 0.999 0.94 – 1.06 0.984 1120 11458 exclusion phecode
221 Benign neoplasm of other female genital organs Neoplasms 0.863 0.736 – 1.01 0.0712 173 1750 exclusion phecode
222 Benign neoplasm of male genital organs Neoplasms 1.16 0.952 – 1.42 0.14 94 1038 exclusion phecode
223
Benign neoplasm of kidney and other urinary
Benign neoplasm of kidney and other urinary organs
 Neoplasms 1.17 0.965 – 1.42 0.11 100 1152 exclusion phecode
224 Benign neoplasm of eye Neoplasms 1.17 0.942 – 1.46 0.155 78 954 exclusion phecode
224.1 Benign neoplasm of eye, uveal Neoplasms 1.3 0.949 – 1.77 0.102 37 458 exclusion phecode
225
Benign neoplasm of brain and other parts of
Benign neoplasm of brain and other parts of nervous system
 Neoplasms 0.948 0.869 – 1.04 0.235 563 5999 exclusion phecode
225.1
Benign neoplasm of brain, cranial nerves
Benign neoplasm of brain, cranial nerves, meninges
 Neoplasms 0.97 0.887 – 1.06 0.501 528 5694 exclusion phecode
225.2 Benign neoplasm of spinal cord, meninges Neoplasms 0.783 0.561 – 1.09 0.15 43 455 exclusion phecode
226 Benign neoplasm of thyroid glands Neoplasms 0.865 0.745 – 1 0.058 196 2039 exclusion phecode
227
Benign neoplasm of other endocrine glands and
Benign neoplasm of other endocrine glands and related structures
 Neoplasms 1.07 0.979 – 1.16 0.143 548 6287 exclusion phecode
227.1 Benign neoplasm of adrenal gland Neoplasms 1.05 0.869 – 1.27 0.601 106 1354 exclusion phecode
227.2 Benign neoplasm of parathyroid gland Neoplasms 1.13 0.991 – 1.28 0.0697 237 2662 exclusion phecode
227.3
Benign neoplasm of pituitary gland and
Benign neoplasm of pituitary gland and craniopharyngeal duct (pouch)
 Neoplasms 1.03 0.896 – 1.19 0.664 204 2262 exclusion phecode
228 Hemangioma and lymphangioma, any site Neoplasms 0.968 0.911 – 1.03 0.293 1141 11659 exclusion phecode
229 Benign neoplasm of unspecified sites Neoplasms 1.03 0.986 – 1.09 0.165 1842 18187 exclusion phecode
240 Simple and unspecified goiter Endocrine/metabolic 1.04 0.945 – 1.15 0.4 414 4535 exclusion phecode
241 Nontoxic nodular goiter Endocrine/metabolic 0.951 0.883 – 1.02 0.178 779 8411 exclusion phecode
241.1 Nontoxic uninodular goiter Endocrine/metabolic 1.05 0.939 – 1.17 0.405 357 3598 exclusion phecode
241.2 Nontoxic multinodular goiter Endocrine/metabolic 0.888 0.805 – 0.979 0.0172 451 5090 exclusion phecode
242 Thyrotoxicosis with or without goiter Endocrine/metabolic 1.04 0.985 – 1.11 0.148 1162 13999 exclusion phecode
242.1 Graves' disease Endocrine/metabolic 1.01 0.9 – 1.13 0.894 327 3632 exclusion phecode
242.2 Toxic multinodular goiter Endocrine/metabolic 0.999 0.774 – 1.29 0.992 57 715 exclusion phecode
242.3 Exophthalmos Endocrine/metabolic 0.984 0.798 – 1.21 0.881 95 1059 exclusion phecode
244 Hypothyroidism Endocrine/metabolic 1.06 1.03 – 1.08 3.66e-07 9219 108660 exclusion phecode
244.1 Secondary hypothyroidism Endocrine/metabolic 1.07 0.989 – 1.15 0.092 700 8273 exclusion phecode
244.2 Acquired hypothyroidism Endocrine/metabolic 1.06 0.804 – 1.39 0.688 60 769 exclusion phecode
244.4 Hypothyroidism NOS Endocrine/metabolic 1.05 1.03 – 1.08 2.55e-06 8765 103937 exclusion phecode
245 Thyroiditis Endocrine/metabolic 0.927 0.801 – 1.07 0.311 201 2279 exclusion phecode
245.2 Chronic thyroiditis Endocrine/metabolic 0.943 0.798 – 1.11 0.487 153 1716 exclusion phecode
245.21 Chronic lymphocytic thyroiditis Endocrine/metabolic 0.963 0.813 – 1.14 0.665 145 1639 exclusion phecode
246 Other disorders of thyroid Endocrine/metabolic 1.04 0.92 – 1.18 0.507 260 3014 exclusion phecode
250 Diabetes mellitus Endocrine/metabolic 1.03 1.01 – 1.05 0.0105 10925 131077 exclusion phecode
250.1 Type 1 diabetes Endocrine/metabolic 0.991 0.94 – 1.04 0.723 1489 19737 exclusion phecode
250.11 Type 1 diabetes with ketoacidosis Endocrine/metabolic 0.877 0.738 – 1.04 0.133 140 1800 exclusion phecode
250.12 Type 1 diabetes with renal manifestations Endocrine/metabolic 1.02 0.593 – 1.75 0.95 8 556 exclusion phecode
250.13 Type 1 diabetes with ophthalmic manifestations Endocrine/metabolic 1 0.88 – 1.15 0.947 222 3357 exclusion phecode
250.14 Type 1 diabetes with neurological manifestations Endocrine/metabolic 0.974 0.746 – 1.27 0.845 51 1141 exclusion phecode
250.2 Type 2 diabetes Endocrine/metabolic 1.03 1.01 – 1.05 0.00376 9579 118577 exclusion phecode
250.21 Type 2 diabetes with ketoacidosis Endocrine/metabolic 1.04 0.802 – 1.36 0.749 61 768 exclusion phecode
250.22 Type 2 diabetes with renal manifestations Endocrine/metabolic 1.17 0.824 – 1.67 0.376 25 1338 exclusion phecode
250.23 Type 2 diabetes with ophthalmic manifestations Endocrine/metabolic 1.08 0.976 – 1.19 0.138 397 6711 exclusion phecode
250.24 Type 2 diabetes with neurological manifestations Endocrine/metabolic 1.06 0.906 – 1.23 0.485 164 3447 exclusion phecode
250.4 Abnormal glucose Endocrine/metabolic 0.94 0.848 – 1.04 0.236 400 4888 exclusion phecode
250.41 Impaired fasting glucose Endocrine/metabolic 0.967 0.828 – 1.13 0.667 172 1858 exclusion phecode
250.42 Other abnormal glucose Endocrine/metabolic 0.931 0.813 – 1.07 0.302 228 3014 exclusion phecode
250.5 Glycosuria or Acetonuria Endocrine/metabolic 0.95 0.77 – 1.17 0.634 104 1107 exclusion phecode
250.6 Polyneuropathy in diabetes Endocrine/metabolic 0.996 0.838 – 1.18 0.961 124 2404 exclusion phecode
250.7 Diabetic retinopathy Endocrine/metabolic 1.02 0.94 – 1.11 0.64 596 9087 exclusion phecode
251.1 Hypoglycemia Endocrine/metabolic 0.937 0.852 – 1.03 0.181 451 6676 exclusion phecode
252 Disorders of parathyroid gland Endocrine/metabolic 1.12 1.02 – 1.22 0.0208 461 6281 exclusion phecode
252.1 Hyperparathyroidism Endocrine/metabolic 1.08 0.982 – 1.19 0.111 417 5639 exclusion phecode
252.2 Hypoparathyroidism Endocrine/metabolic 1.4 1.09 – 1.79 0.00742 59 1003 exclusion phecode
253
Disorders of the pituitary gland and its
Disorders of the pituitary gland and its hypothalamic control
 Endocrine/metabolic 1.05 0.951 – 1.16 0.339 413 4880 exclusion phecode
253.1 Pituitary hyperfunction Endocrine/metabolic 1.03 0.858 – 1.23 0.759 122 1392 exclusion phecode
253.11 Acromegaly and gigantism Endocrine/metabolic 1.18 0.926 – 1.5 0.182 61 699 exclusion phecode
253.2 Pituitary hypofunction Endocrine/metabolic 1.01 0.857 – 1.2 0.882 143 1869 exclusion phecode
253.3 Diabetes insipidus Endocrine/metabolic 0.749 0.555 – 1.01 0.0579 47 715 exclusion phecode
253.7 Other disorders of neurohypophysis Endocrine/metabolic 1.13 0.937 – 1.36 0.202 107 1033 exclusion phecode
255 Disorders of adrenal glands Endocrine/metabolic 0.995 0.89 – 1.11 0.929 337 4714 exclusion phecode
255.1 Adrenal hyperfunction Endocrine/metabolic 1.13 0.915 – 1.39 0.258 90 1352 exclusion phecode
255.11 Cushing's syndrome Endocrine/metabolic 1.06 0.8 – 1.4 0.689 52 805 exclusion phecode
255.12 Hyperaldosteronism Endocrine/metabolic 1.13 0.812 – 1.56 0.476 38 549 exclusion phecode
255.2 Adrenal hypofunction Endocrine/metabolic 1.05 0.901 – 1.21 0.557 185 2651 exclusion phecode
255.21 Glucocorticoid deficiency Endocrine/metabolic 1.04 0.899 – 1.21 0.575 185 2645 exclusion phecode
256 Ovarian dysfunction Endocrine/metabolic 1.01 0.877 – 1.17 0.844 204 2141 exclusion phecode
256.4 Polycystic ovaries Endocrine/metabolic 1.02 0.871 – 1.19 0.815 174 1876 exclusion phecode
257 Testicular dysfunction Endocrine/metabolic 1.12 0.911 – 1.38 0.278 87 1131 exclusion phecode
257.1 Testicular hypofunction Endocrine/metabolic 1.16 0.93 – 1.44 0.19 80 1064 exclusion phecode
258 Iatrogenic endocrine disorders Endocrine/metabolic 1.06 0.817 – 1.38 0.654 55 752 exclusion phecode
259 Other endocrine disorders Endocrine/metabolic 1.06 0.869 – 1.29 0.564 102 1134 exclusion phecode
260 Protein-calorie malnutrition Endocrine/metabolic 0.868 0.721 – 1.05 0.136 117 1414 exclusion phecode
260.1 Cachexia Endocrine/metabolic 1.2 0.828 – 1.73 0.339 27 340 exclusion phecode
260.6 Anorexia Endocrine/metabolic 0.992 0.906 – 1.09 0.869 494 5856 exclusion phecode
261 Vitamin deficiency Endocrine/metabolic 1.06 0.983 – 1.15 0.129 692 8706 exclusion phecode
261.2 Vitamin B-complex deficiencies Endocrine/metabolic 1.08 0.978 – 1.18 0.133 440 5454 exclusion phecode
261.4 Vitamin D deficiency Endocrine/metabolic 1.07 0.941 – 1.21 0.311 258 3312 exclusion phecode
261.41 Rickets or osteomalacia Endocrine/metabolic 1.03 0.746 – 1.41 0.87 36 575 exclusion phecode
262 Mineral deficiency NEC Endocrine/metabolic 1.03 0.875 – 1.22 0.707 152 1775 exclusion phecode
269 Proteinuria Endocrine/metabolic 1.12 0.958 – 1.32 0.151 158 2372 exclusion phecode
270
Disorders of protein plasma/amino-acid
Disorders of protein plasma/amino-acid transport and metabolism
 Endocrine/metabolic 1.04 0.895 – 1.22 0.586 160 2051 exclusion phecode
270.3 Disorders of plasma protein metabolism Endocrine/metabolic 1.08 0.909 – 1.27 0.396 134 1749 exclusion phecode
270.32 Paraproteinemia Endocrine/metabolic 1.06 0.868 – 1.3 0.561 94 1263 exclusion phecode
270.33 Amyloidosis Endocrine/metabolic 0.94 0.722 – 1.22 0.647 55 764 exclusion phecode
270.35 Macroglobulinemia Endocrine/metabolic 1.02 0.73 – 1.41 0.925 36 475 exclusion phecode
271
Disorders of carbohydrate transport and
Disorders of carbohydrate transport and metabolism
 Endocrine/metabolic 1.12 0.922 – 1.37 0.248 109 1184 exclusion phecode
271.3
Intestinal disaccharidase deficiencies and
Intestinal disaccharidase deficiencies and disaccharide malabsorption
 Endocrine/metabolic 1.06 0.861 – 1.3 0.587 99 1039 exclusion phecode
272 Disorders of lipoid metabolism Endocrine/metabolic 1.02 1 – 1.03 0.0213 20417 170572 exclusion phecode
272.1 Hyperlipidemia Endocrine/metabolic 1.02 1 – 1.03 0.0235 20374 170389 exclusion phecode
272.11 Hypercholesterolemia Endocrine/metabolic 1.02 1 – 1.04 0.0111 18889 164486 exclusion phecode
272.12 Hyperglyceridemia Endocrine/metabolic 0.888 0.635 – 1.24 0.484 38 411 exclusion phecode
272.13 Mixed hyperlipidemia Endocrine/metabolic 1.11 0.894 – 1.37 0.35 84 1154 exclusion phecode
272.9 Unspecified disorder of lipoid metabolism Endocrine/metabolic 1.16 0.973 – 1.39 0.0965 118 1442 exclusion phecode
274 Gout and other crystal arthropathies Endocrine/metabolic 1.09 1.04 – 1.14 0.000714 1596 24798 exclusion phecode
274.1 Gout Endocrine/metabolic 1.09 1.03 – 1.15 0.00358 1237 20817 exclusion phecode
274.11 Gouty arthropathy Endocrine/metabolic 1.16 0.881 – 1.52 0.293 51 735 exclusion phecode
274.2 Crystal arthropathies Endocrine/metabolic 1.11 0.998 – 1.23 0.0538 384 4360 exclusion phecode
274.21 Chondrocalcinosis Endocrine/metabolic 1.11 0.998 – 1.24 0.0549 356 3988 exclusion phecode
275 Disorders of mineral metabolism Endocrine/metabolic 1.08 1.02 – 1.15 0.00896 1172 14742 exclusion phecode
275.1 Disorders of iron metabolism Hematopoietic 1.05 0.951 – 1.16 0.339 423 4588 exclusion phecode
275.3 Disorders of magnesium metabolism Endocrine/metabolic 1.15 1 – 1.33 0.0469 200 2573 exclusion phecode
275.5 Disorders of calcium/phosphorus metabolism Endocrine/metabolic 1.12 1.04 – 1.22 0.00459 610 8470 exclusion phecode
275.53 Disorders of phosphorus metabolism Endocrine/metabolic 1.17 0.95 – 1.43 0.141 100 1209 exclusion phecode
276
Disorders of fluid, electrolyte, and acid-base
Disorders of fluid, electrolyte, and acid-base balance
 Endocrine/metabolic 1.04 1.01 – 1.08 0.0201 3665 50343 exclusion phecode
276.1 Electrolyte imbalance Endocrine/metabolic 1.07 1.02 – 1.11 0.00385 2110 28095 exclusion phecode
276.11 Hyperosmolality and/or hypernatremia Endocrine/metabolic 1.1 0.925 – 1.32 0.274 121 1585 exclusion phecode
276.12 Hyposmolality and/or hyponatremia Endocrine/metabolic 1.05 0.985 – 1.12 0.135 1071 12445 exclusion phecode
276.13 Hyperpotassemia Endocrine/metabolic 1.06 0.951 – 1.19 0.283 311 6533 exclusion phecode
276.14 Hypopotassemia Endocrine/metabolic 1.1 1.02 – 1.18 0.0107 773 10104 exclusion phecode
276.4 Acid-base balance disorder Endocrine/metabolic 1 0.912 – 1.1 0.969 470 7952 exclusion phecode
276.41 Acidosis Endocrine/metabolic 1.03 0.929 – 1.13 0.62 420 7243 exclusion phecode
276.42 Alkalosis Endocrine/metabolic 0.847 0.632 – 1.13 0.265 52 746 exclusion phecode
276.5 Hypovolemia Endocrine/metabolic 1.02 0.964 – 1.07 0.542 1409 19646 exclusion phecode
276.6 Fluid overload Endocrine/metabolic 1.13 0.967 – 1.32 0.125 151 3022 exclusion phecode
276.8 Polydipsia Endocrine/metabolic 0.937 0.755 – 1.16 0.554 88 971 exclusion phecode
277 Other disorders of metabolism Endocrine/metabolic 1.05 0.957 – 1.14 0.325 517 6497 exclusion phecode
277.4 Disorders of bilirubin excretion Endocrine/metabolic 0.966 0.848 – 1.1 0.607 238 2573 exclusion phecode
277.5 Other disorders of lipoid metabolism Endocrine/metabolic 1.04 0.872 – 1.23 0.682 132 1611 exclusion phecode
277.51 Lipoprotein disorders Endocrine/metabolic 1.2 0.814 – 1.77 0.357 26 367 exclusion phecode
278 Overweight, obesity and other hyperalimentation Endocrine/metabolic 1.1 1.07 – 1.13 5.28e-13 5600 79880 exclusion phecode
278.1 Obesity Endocrine/metabolic 1.1 1.07 – 1.13 8.13e-13 5501 78655 exclusion phecode
278.3 Localized adiposity Endocrine/metabolic 1.06 0.828 – 1.35 0.65 61 686 exclusion phecode
278.4 Abnormal weight gain Endocrine/metabolic 1.37 0.983 – 1.9 0.0633 32 510 exclusion phecode
279 Disorders involving the immune mechanism Endocrine/metabolic 1.09 0.918 – 1.28 0.335 144 1853 exclusion phecode
279.1 Immunity deficiency Endocrine/metabolic 1.11 0.93 – 1.33 0.241 121 1545 exclusion phecode
279.11 Deficiency of humoral immunity Endocrine/metabolic 1.21 0.966 – 1.52 0.0973 77 1012 exclusion phecode
279.7 Other immunological findings Endocrine/metabolic 0.984 0.838 – 1.16 0.846 164 1594 exclusion phecode
280 Iron deficiency anemias Hematopoietic 1.01 0.982 – 1.04 0.453 4717 56023 exclusion phecode
280.1
Iron deficiency anemias, unspecified or not due
Iron deficiency anemias, unspecified or not due to blood loss
 Hematopoietic 1.01 0.978 – 1.04 0.611 4497 53665 exclusion phecode
280.2
Iron deficiency anemia secondary to blood loss
Iron deficiency anemia secondary to blood loss (chronic)
 Hematopoietic 1.02 0.909 – 1.15 0.736 322 3555 exclusion phecode
281 Other deficiency anemia Hematopoietic 1.04 0.958 – 1.13 0.353 613 8034 exclusion phecode
281.1 Megaloblastic anemia Hematopoietic 1.03 0.947 – 1.12 0.501 593 7703 exclusion phecode
281.11 Pernicious anemia Hematopoietic 1.04 0.942 – 1.14 0.452 430 5434 exclusion phecode
281.12 Other vitamin B12 deficiency anemia Hematopoietic 1.03 0.848 – 1.26 0.742 103 1327 exclusion phecode
281.13 Folate-deficiency anemia Hematopoietic 0.996 0.797 – 1.24 0.97 80 1277 exclusion phecode
281.9 Deficiency anemias Hematopoietic 1.57 1.04 – 2.37 0.0324 23 369 exclusion phecode
282 Hereditary hemolytic anemias Hematopoietic 1 0.804 – 1.25 0.982 77 1087 exclusion phecode
282.8 Other hemoglobinopathies Hematopoietic 0.941 0.668 – 1.33 0.73 33 406 exclusion phecode
282.9 Other hereditary hemolytic anemias Hematopoietic 1.06 0.785 – 1.43 0.707 42 618 exclusion phecode
283 Acquired hemolytic anemias Hematopoietic 1.02 0.784 – 1.32 0.907 59 972 exclusion phecode
283.1 Autoimmune hemolytic anemias Hematopoietic 0.876 0.643 – 1.19 0.4 45 730 exclusion phecode
284 Aplastic anemia Hematopoietic 1.11 0.961 – 1.27 0.159 200 3051 exclusion phecode
285 Other anemias Hematopoietic 1.02 0.993 – 1.04 0.162 7059 87513 exclusion phecode
285.1 Acute posthemorrhagic anemia Hematopoietic 0.893 0.766 – 1.04 0.147 185 2064 exclusion phecode
285.2 Anemia of chronic disease Hematopoietic 1.13 1 – 1.27 0.0436 268 4887 exclusion phecode
285.22 Anemia in neoplastic disease Hematopoietic 1.12 0.99 – 1.28 0.0719 235 2923 exclusion phecode
286 Coagulation defects Hematopoietic 0.994 0.912 – 1.08 0.884 557 6766 exclusion phecode
286.1 Congenital coagulation defects Hematopoietic 0.949 0.844 – 1.07 0.38 317 3459 exclusion phecode
286.11 Von willebrand's disease Hematopoietic 0.869 0.681 – 1.11 0.257 74 734 exclusion phecode
286.12
Congenital deficiency of other clotting factors
Congenital deficiency of other clotting factors (including factor VII)
 Hematopoietic 0.968 0.837 – 1.12 0.666 201 2233 exclusion phecode
286.13 Congenital factor VIII disorder Hematopoietic 1.01 0.746 – 1.37 0.945 38 460 exclusion phecode
286.5
Hemorrhagic disorder due to intrinsic
Hemorrhagic disorder due to intrinsic circulating anticoagulants
 Hematopoietic 1.4 1.01 – 1.93 0.044 29 569 exclusion phecode
286.7 Other and unspecified coagulation defects Hematopoietic 1.02 0.894 – 1.17 0.736 218 2823 exclusion phecode
287 Purpura and other hemorrhagic conditions Hematopoietic 1.08 1 – 1.15 0.0365 868 11543 exclusion phecode
287.1 Spontaneous ecchymoses Hematopoietic 1.01 0.805 – 1.26 0.961 80 916 exclusion phecode
287.2 Allergic purpura Hematopoietic 1.07 0.767 – 1.5 0.681 30 395 exclusion phecode
287.3 Thrombocytopenia Hematopoietic 1.05 0.975 – 1.12 0.207 812 10830 exclusion phecode
287.31 Primary thrombocytopenia Hematopoietic 1 0.872 – 1.15 0.989 214 2939 exclusion phecode
287.32 Secondary thrombocytopenia Hematopoietic 0.805 0.553 – 1.17 0.258 32 507 exclusion phecode
288 Diseases of white blood cells Hematopoietic 1.02 0.98 – 1.07 0.31 2279 27246 exclusion phecode
288.1 Decreased white blood cell count Hematopoietic 1.01 0.967 – 1.06 0.591 1930 22983 exclusion phecode
288.11 Neutropenia Hematopoietic 1.01 0.966 – 1.06 0.606 1937 23042 exclusion phecode
288.3 Eosinophilia Hematopoietic 1.38 1.03 – 1.86 0.0317 40 499 exclusion phecode
289 Other diseases of blood and blood-forming organs Hematopoietic 1.05 0.955 – 1.15 0.322 474 6221 exclusion phecode
289.3
Personal history of diseases of blood and
Personal history of diseases of blood and blood-forming organs
 Hematopoietic 0.935 0.798 – 1.1 0.409 164 2167 exclusion phecode
289.4 Lymphadenitis Hematopoietic 1.06 1 – 1.11 0.032 1575 18736 exclusion phecode
289.5 Diseases of spleen Hematopoietic 0.982 0.872 – 1.11 0.762 291 3627 exclusion phecode
289.8 Polycythemia, secondary Hematopoietic 1.08 0.91 – 1.27 0.387 133 2006 exclusion phecode
289.9 Abnormality of red blood cells Hematopoietic 1.3 0.964 – 1.75 0.0858 38 649 exclusion phecode
290
Delirium dementia and amnestic and other
Delirium dementia and amnestic and other cognitive disorders
 Mental Disorders 0.975 0.915 – 1.04 0.438 1010 12458 exclusion phecode
290.1 Dementias Mental Disorders 1 0.917 – 1.09 0.994 540 6269 exclusion phecode
290.11 Alzheimer's disease Mental Disorders 1 0.883 – 1.14 0.968 252 2750 exclusion phecode
290.16 Vascular dementia Mental Disorders 1.06 0.869 – 1.28 0.582 99 1219 exclusion phecode
290.2 Delirium due to conditions classified elsewhere Mental Disorders 0.912 0.813 – 1.02 0.112 328 4252 exclusion phecode
290.3
Other persistent mental disorders due to
Other persistent mental disorders due to conditions classified elsewhere
 Mental Disorders 1.18 0.884 – 1.58 0.261 42 558 exclusion phecode
291
Other specified nonpsychotic and/or transient
Other specified nonpsychotic and/or transient mental disorders
 Mental Disorders 0.976 0.891 – 1.07 0.611 499 6087 exclusion phecode
291.1
Transient mental disorders due to conditions
Transient mental disorders due to conditions classified elsewhere
 Mental Disorders 1.1 0.888 – 1.35 0.393 95 1045 exclusion phecode
291.4
Specific nonpsychotic mental disorders due to
Specific nonpsychotic mental disorders due to brain damage
 Mental Disorders 0.878 0.746 – 1.03 0.115 163 1978 exclusion phecode
291.8 Alteration of consciousness Mental Disorders 1.04 0.915 – 1.18 0.562 255 3192 exclusion phecode
292 Neurological disorders Mental Disorders 1.04 1 – 1.08 0.0489 2712 31905 exclusion phecode
292.1 Aphasia/speech disturbance Mental Disorders 1.04 0.971 – 1.11 0.276 906 10596 exclusion phecode
292.2 Mild cognitive impairment Mental Disorders 0.961 0.786 – 1.17 0.696 99 1299 exclusion phecode
292.3 Memory loss Mental Disorders 1.04 0.947 – 1.14 0.417 469 4916 exclusion phecode
292.4 Altered mental status Mental Disorders 1.02 0.967 – 1.09 0.407 1211 14671 exclusion phecode
292.6 Hallucinations Mental Disorders 1.1 0.948 – 1.28 0.202 171 2166 exclusion phecode
293 Symptoms involving head and neck Mental Disorders 1.05 0.992 – 1.1 0.0984 1419 15198 exclusion phecode
293.1
Swelling, mass, or lump in head and neck
Swelling, mass, or lump in head and neck [Space-occupying lesion, intracranial NOS]
 Mental Disorders 0.974 0.897 – 1.06 0.536 605 6623 exclusion phecode
295 Schizophrenia and other psychotic disorders Mental Disorders 0.966 0.88 – 1.06 0.468 493 6382 exclusion phecode
295.1 Schizophrenia Mental Disorders 0.986 0.88 – 1.1 0.812 326 4364 exclusion phecode
295.2 Paranoid disorders Mental Disorders 0.983 0.813 – 1.19 0.861 111 1363 exclusion phecode
295.3 Psychosis Mental Disorders 0.875 0.713 – 1.08 0.205 101 1317 exclusion phecode
296 Mood disorders Mental Disorders 1.05 1.03 – 1.08 4.52e-06 8082 94942 exclusion phecode
296.1 Bipolar Mental Disorders 1.09 1 – 1.18 0.0454 632 8089 exclusion phecode
296.2 Depression Mental Disorders 1.05 1.03 – 1.08 1.38e-05 7697 90087 exclusion phecode
296.22 Major depressive disorder Mental Disorders 0.993 0.868 – 1.14 0.918 228 2742 exclusion phecode
297.2 Suicide or self-inflicted injury Mental Disorders 0.956 0.83 – 1.1 0.536 208 2413 exclusion phecode
300 Anxiety disorders Mental Disorders 1.02 0.993 – 1.05 0.135 4624 51851 exclusion phecode
300.1 Anxiety disorder Mental Disorders 1.02 0.988 – 1.05 0.229 4282 47836 exclusion phecode
300.11 Generalized anxiety disorder Mental Disorders 1.08 0.891 – 1.3 0.445 109 1153 exclusion phecode
300.12 Agorophobia, social phobia, and panic disorder Mental Disorders 1.03 0.936 – 1.13 0.569 474 5403 exclusion phecode
300.13 Phobia Mental Disorders 1.01 0.906 – 1.14 0.809 326 3766 exclusion phecode
300.3 Obsessive-compulsive disorders Mental Disorders 0.869 0.706 – 1.07 0.185 97 1080 exclusion phecode
300.4 Dysthymic disorder Mental Disorders 1.23 0.901 – 1.68 0.192 37 419 exclusion phecode
300.8 Acute reaction to stress Mental Disorders 1.09 0.876 – 1.36 0.438 86 965 exclusion phecode
300.9 Posttraumatic stress disorder Mental Disorders 1.11 0.889 – 1.39 0.352 80 891 exclusion phecode
301 Personality disorders Mental Disorders 1.24 1.08 – 1.42 0.00226 203 2700 exclusion phecode
301.2 Antisocial/borderline personality disorder Mental Disorders 1.33 1.06 – 1.67 0.0137 74 1010 exclusion phecode
302 Sexual and gender identity disorders Mental Disorders 1.03 0.875 – 1.21 0.735 162 1890 exclusion phecode
303 Psychogenic and somatoform disorders Mental Disorders 1.08 0.968 – 1.21 0.167 327 3543 exclusion phecode
303.3 Psychogenic disorder Mental Disorders 1.02 0.899 – 1.17 0.714 252 2625 exclusion phecode
303.4 Somatoform disorder Mental Disorders 1.15 0.928 – 1.43 0.197 82 960 exclusion phecode
304 Adjustment reaction Mental Disorders 1.04 0.897 – 1.2 0.634 202 2288 exclusion phecode
305.2 Eating disorder Mental Disorders 1.02 0.802 – 1.29 0.883 73 763 exclusion phecode
306 Other mental disorder Mental Disorders 1.03 1.01 – 1.04 0.00151 17030 167354 exclusion phecode
306.9 Tension headache Mental Disorders 1.03 0.895 – 1.18 0.705 218 2489 exclusion phecode
313 Pervasive developmental disorders Mental Disorders 0.922 0.706 – 1.2 0.551 54 593 exclusion phecode
313.3 Autism Mental Disorders 1.21 0.89 – 1.63 0.228 39 409 exclusion phecode
315 Develomental delays and disorders Mental Disorders 1.05 0.91 – 1.21 0.505 200 2513 exclusion phecode
315.1 Learning disorder Mental Disorders 0.966 0.771 – 1.21 0.767 83 1248 exclusion phecode
315.2 Speech and language disorder Mental Disorders 0.984 0.743 – 1.3 0.913 50 615 exclusion phecode
316 Substance addiction and disorders Mental Disorders 1.04 1 – 1.08 0.0329 3375 39026 exclusion phecode
316.1 Polyneuropathy due to drugs Mental Disorders 0.944 0.657 – 1.36 0.754 31 449 exclusion phecode
317 Alcohol-related disorders Mental Disorders 1.01 0.991 – 1.04 0.233 8591 92459 exclusion phecode
317.1 Alcoholism Mental Disorders 1 0.978 – 1.03 0.791 6050 64215 exclusion phecode
317.11 Alcoholic liver damage Mental Disorders 1.01 0.922 – 1.11 0.789 450 6050 exclusion phecode
318 Tobacco use disorder Mental Disorders 1.05 1.03 – 1.07 5.89e-07 11090 136722 exclusion phecode
320 Meningitis Neurological 0.98 0.872 – 1.1 0.735 314 3432 exclusion phecode
323 Encephalitis Neurological 1.08 0.953 – 1.23 0.219 242 2561 exclusion phecode
323.2 Acute (transverse) myelitis Neurological 1.27 0.997 – 1.63 0.0532 62 590 exclusion phecode
324 Other CNS infection and poliomyelitis Neurological 1.11 0.961 – 1.29 0.153 186 2017 exclusion phecode
327 Sleep disorders Neurological 1.1 1.03 – 1.19 0.00816 753 8299 exclusion phecode
327.3 Sleep apnea Neurological 1.05 1.01 – 1.1 0.0131 2509 31613 exclusion phecode
327.4 Insomnia Neurological 1.05 0.868 – 1.27 0.609 106 1206 exclusion phecode
327.41 Organic or persistent insomnia Neurological 1.08 0.875 – 1.33 0.486 89 1012 exclusion phecode
331 Other cerebral degenerations Neurological 1.02 0.94 – 1.1 0.695 688 7941 exclusion phecode
331.1 Hydrocephalus Neurological 0.979 0.873 – 1.1 0.723 320 3620 exclusion phecode
331.9 Cerebral degeneration, unspecified Neurological 1.07 0.947 – 1.22 0.265 245 2859 exclusion phecode
332 Parkinson's disease Neurological 1.08 1 – 1.17 0.0448 696 7283 exclusion phecode
333
Extrapyramidal disease and abnormal movement
Extrapyramidal disease and abnormal movement disorders
 Neurological 1.09 1.01 – 1.19 0.0352 563 6369 exclusion phecode
333.1 Essential tremor Neurological 1.19 0.99 – 1.42 0.0635 119 1443 exclusion phecode
333.2 Myoclonus Neurological 1.17 0.911 – 1.51 0.216 65 700 exclusion phecode
333.4 Torsion dystonia Neurological 0.922 0.785 – 1.08 0.325 169 1872 exclusion phecode
334 Degenerative disease of the spinal cord Neurological 1.02 0.963 – 1.09 0.462 1142 12828 exclusion phecode
334.1 Spinocerebellar disease Neurological 1.1 0.861 – 1.4 0.45 65 836 exclusion phecode
334.2 Anterior horn cell disease Neurological 1.19 1.02 – 1.4 0.0302 159 1626 exclusion phecode
335 Multiple sclerosis Neurological 1.02 0.955 – 1.09 0.574 1001 10396 exclusion phecode
337 Disorders of the autonomic nervous system Neurological 1.02 0.872 – 1.2 0.776 157 1874 exclusion phecode
337.1 Peripheral autonomic neuropathy Neurological 0.944 0.687 – 1.3 0.72 36 467 exclusion phecode
338 Pain Neurological 1.1 1 – 1.21 0.0459 465 5734 exclusion phecode
338.1 Acute pain Neurological 1.07 0.937 – 1.22 0.315 226 2898 exclusion phecode
338.2 Chronic pain Neurological 1.09 0.96 – 1.24 0.184 242 2934 exclusion phecode
339 Other headache syndromes Neurological 1.01 0.985 – 1.04 0.382 5457 59083 exclusion phecode
340 Migraine Neurological 0.994 0.95 – 1.04 0.8 2104 22427 exclusion phecode
340.1 Migrain with aura Neurological 0.947 0.801 – 1.12 0.524 154 1692 exclusion phecode
341
Other demyelinating diseases of central nervous
Other demyelinating diseases of central nervous system
 Neurological 1.01 0.867 – 1.17 0.913 196 1993 exclusion phecode
342 Hemiplegia Neurological 1.08 1.01 – 1.16 0.0339 811 10529 exclusion phecode
343 Infantile cerebral palsy Neurological 0.78 0.629 – 0.969 0.0248 101 1092 exclusion phecode
344 Other paralytic syndromes Neurological 1.03 0.929 – 1.13 0.617 415 4841 exclusion phecode
345 Epilepsy, recurrent seizures, convulsions Neurological 1 0.969 – 1.04 0.839 3449 36984 exclusion phecode
345.1 Epilepsy Neurological 0.998 0.917 – 1.09 0.958 600 6422 exclusion phecode
345.11 Generalized convulsive epilepsy Neurological 1.05 0.939 – 1.18 0.373 313 3237 exclusion phecode
345.12 Partial epilepsy Neurological 1 0.868 – 1.16 0.973 200 2113 exclusion phecode
345.3 Convulsions Neurological 1.02 0.969 – 1.08 0.436 1513 16471 exclusion phecode
346.1
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of skull and head
 Neurological 1.02 0.836 – 1.25 0.825 91 1064 exclusion phecode
348 Other conditions of brain Neurological 1.1 0.998 – 1.2 0.0551 469 5731 exclusion phecode
348.2 Cerebral edema and compression of brain Neurological 1.09 0.929 – 1.27 0.296 159 2021 exclusion phecode
348.4 Cerebral cysts Neurological 1.16 0.945 – 1.42 0.159 97 1023 exclusion phecode
348.7 Coma Neurological 0.974 0.854 – 1.11 0.691 244 2540 exclusion phecode
348.8 Encephalopathy, not elsewhere classified Neurological 1.12 0.95 – 1.32 0.179 147 1803 exclusion phecode
348.9 Other conditions of brain, NOS Neurological 1.04 0.914 – 1.17 0.577 266 2780 exclusion phecode
349
Other and unspecified disorders of the nervous
Other and unspecified disorders of the nervous system
 Neurological 0.964 0.843 – 1.1 0.599 221 2482 exclusion phecode
350 Abnormal movement Neurological 1.06 1.01 – 1.12 0.0231 1558 18808 exclusion phecode
350.1 Abnormal involuntary movements Neurological 1.04 0.95 – 1.13 0.412 540 6480 exclusion phecode
350.2 Abnormality of gait Neurological 1.06 0.993 – 1.14 0.0808 884 10945 exclusion phecode
350.3 Lack of coordination Neurological 1.04 0.912 – 1.19 0.54 223 2634 exclusion phecode
350.6 Disturbances of sensation of smell and taste Neurological 0.995 0.727 – 1.36 0.974 39 397 exclusion phecode
351 Other peripheral nerve disorders Neurological 0.997 0.975 – 1.02 0.787 8509 92624 exclusion phecode
352 Disorders of other cranial nerves Neurological 1.01 0.947 – 1.08 0.697 903 9985 exclusion phecode
352.1 Trigeminal nerve disorders [CN5] Neurological 0.992 0.886 – 1.11 0.883 319 3438 exclusion phecode
352.2 Facial nerve disorders [CN7] Neurological 0.978 0.898 – 1.07 0.615 565 6376 exclusion phecode
353 Nerve root and plexus disorders Neurological 1.01 0.938 – 1.1 0.724 692 8200 exclusion phecode
353.1 Nerve plexus lesions Neurological 0.889 0.702 – 1.13 0.329 79 883 exclusion phecode
353.2 Nerve root lesions Neurological 1.07 0.782 – 1.48 0.658 36 413 exclusion phecode
356 Hereditary and idiopathic peripheral neuropathy Neurological 1.18 0.963 – 1.46 0.109 93 1075 exclusion phecode
357 Inflammatory and toxic neuropathy Neurological 1.13 1.05 – 1.21 0.00127 759 9463 exclusion phecode
358 Myoneural disorders Neurological 0.999 0.831 – 1.2 0.99 113 1447 exclusion phecode
358.1 Myasthenia gravis Neurological 1.06 0.88 – 1.29 0.521 105 1336 exclusion phecode
359 Muscular dystrophies and other myopathies Neurological 1.09 0.959 – 1.23 0.192 245 3358 exclusion phecode
359.1 Muscular dystrophies Neurological 1.02 0.793 – 1.31 0.891 61 888 exclusion phecode
359.2 Myopathy Neurological 1.13 0.977 – 1.31 0.099 190 2586 exclusion phecode
360 Disorders of the globe Sense Organs 0.958 0.836 – 1.1 0.536 226 2287 exclusion phecode
360.2 Progressive myopia Sense Organs 0.976 0.835 – 1.14 0.757 167 1721 exclusion phecode
361 Retinal detachments and defects Sense Organs 0.989 0.947 – 1.03 0.602 2307 22703 exclusion phecode
361.1 Retinal detachment with retinal defect Sense Organs 0.985 0.922 – 1.05 0.645 980 9779 exclusion phecode
361.2 Retinoschisis and retinal cysts Sense Organs 0.944 0.685 – 1.3 0.725 40 490 exclusion phecode
362 Other retinal disorders Sense Organs 1.03 0.987 – 1.07 0.184 2379 25973 exclusion phecode
362.2
Degeneration of macula and posterior pole of
Degeneration of macula and posterior pole of retina
 Sense Organs 1.05 0.995 – 1.11 0.0734 1374 14566 exclusion phecode
362.29 Macular degeneration (senile) of retina NOS Sense Organs 1.05 0.994 – 1.11 0.0793 1372 14540 exclusion phecode
362.3 Other nondiabetic retinopathy Sense Organs 1.06 0.88 – 1.28 0.528 106 1132 exclusion phecode
362.31 Separation of retinal layers Sense Organs 1.06 0.852 – 1.33 0.587 76 683 exclusion phecode
362.4 Retinal vascular changes and abnomalities Sense Organs 1.06 0.968 – 1.16 0.21 475 5694 exclusion phecode
362.6 Peripheral retinal degenerations Sense Organs 0.873 0.727 – 1.05 0.147 126 1302 exclusion phecode
362.7 Hereditary retinal dystrophies Sense Organs 0.806 0.615 – 1.06 0.118 61 584 exclusion phecode
362.8 Retinal hemorrhage/ischemia Sense Organs 0.937 0.749 – 1.17 0.573 79 801 exclusion phecode
363
Chorioretinal inflammations, scars, and other
Chorioretinal inflammations, scars, and other disorders of choroid
 Sense Organs 0.997 0.814 – 1.22 0.979 104 1221 exclusion phecode
363.3 Chorioretinal scars Sense Organs 1.02 0.727 – 1.43 0.917 34 506 exclusion phecode
364 Corneal opacity and other disorders of cornea Sense Organs 0.982 0.891 – 1.08 0.715 440 4556 exclusion phecode
364.1 Corneal opacity Sense Organs 1.13 0.875 – 1.46 0.348 58 650 exclusion phecode
364.2 Corneal edema Sense Organs 0.835 0.607 – 1.15 0.27 43 547 exclusion phecode
364.4 Corneal degenerations Sense Organs 1.15 0.978 – 1.36 0.0907 149 1459 exclusion phecode
364.41 Keratoconus Sense Organs 1.16 0.915 – 1.47 0.221 66 667 exclusion phecode
364.5 Corneal dystrophy Sense Organs 0.865 0.721 – 1.04 0.115 136 1407 exclusion phecode
364.9 Cornea replaced by transplant Sense Organs 0.845 0.666 – 1.07 0.167 69 706 exclusion phecode
365 Glaucoma Sense Organs 1 0.962 – 1.04 0.99 2838 29671 exclusion phecode
365.1 Open-angle glaucoma Sense Organs 1.03 0.953 – 1.11 0.466 674 6777 exclusion phecode
365.11 Primary open angle glaucoma Sense Organs 1.03 0.955 – 1.12 0.417 670 6746 exclusion phecode
365.2 Primary angle-closure glaucoma Sense Organs 1.02 0.93 – 1.12 0.663 477 4805 exclusion phecode
366 Cataract Sense Organs 1.01 0.991 – 1.03 0.311 12277 115766 exclusion phecode
366.1 Nonsenile Cataract Sense Organs 1.01 0.743 – 1.36 0.972 42 517 exclusion phecode
366.2 Senile cataract Sense Organs 1.01 0.979 – 1.04 0.613 5021 54573 exclusion phecode
366.3 Traumatic cataract Sense Organs 1.17 0.923 – 1.48 0.195 69 681 exclusion phecode
367
Disorders of refraction and accommodation
Disorders of refraction and accommodation; blindness and low vision
 Sense Organs 0.986 0.937 – 1.04 0.598 1610 16847 exclusion phecode
367.1 Myopia Sense Organs 1.02 0.952 – 1.09 0.584 880 8778 exclusion phecode
367.2 Astigmatism Sense Organs 0.968 0.803 – 1.17 0.732 124 1340 exclusion phecode
367.8 Hypermetropia Sense Organs 1.03 0.872 – 1.2 0.762 162 1737 exclusion phecode
367.9 Blindness and low vision Sense Organs 0.927 0.841 – 1.02 0.129 439 4993 exclusion phecode
368 Visual disturbances Sense Organs 1.06 1.01 – 1.11 0.0135 1896 21389 exclusion phecode
368.1 Amblyopia Sense Organs 0.986 0.881 – 1.1 0.813 320 3683 exclusion phecode
368.2 Diplopia and disorders of binocular vision Sense Organs 1.07 0.972 – 1.17 0.172 454 5275 exclusion phecode
368.3 Anisometropia Sense Organs 1.17 0.97 – 1.42 0.0995 103 1123 exclusion phecode
368.4 Visual field defects Sense Organs 1.1 0.96 – 1.27 0.166 209 2315 exclusion phecode
368.9 Subjective visual disturbances Sense Organs 1.15 1.04 – 1.27 0.00514 395 4538 exclusion phecode
369 Infection of the eye Sense Organs 1.11 0.994 – 1.23 0.0635 353 4013 exclusion phecode
369.2 Eye infection, viral Sense Organs 1.08 0.852 – 1.36 0.542 72 887 exclusion phecode
369.5 Conjunctivitis, infectious Sense Organs 1.06 0.885 – 1.27 0.531 131 1554 exclusion phecode
370 Keratitis Sense Organs 0.998 0.86 – 1.16 0.974 190 2088 exclusion phecode
370.1 Corneal ulcer Sense Organs 0.947 0.773 – 1.16 0.6 97 1021 exclusion phecode
371 Inflammation of the eye Sense Organs 1.04 0.992 – 1.08 0.106 2192 22200 exclusion phecode
371.1 Uveitis, noninfectious or NOS Sense Organs 1.04 0.932 – 1.17 0.453 307 3471 exclusion phecode
371.3 Inflammation of eyelids Sense Organs 1.04 0.989 – 1.09 0.129 1752 17237 exclusion phecode
372 Disorders of conjunctiva Sense Organs 1.02 0.934 – 1.12 0.652 529 5408 exclusion phecode
374 Other disorders of eyelids Sense Organs 1.01 0.976 – 1.04 0.6 3803 40161 exclusion phecode
374.1 Ectropion or entropion Sense Organs 0.964 0.889 – 1.05 0.379 641 6965 exclusion phecode
374.3 Ptosis of eyelid Sense Organs 1.01 0.956 – 1.07 0.653 1222 12800 exclusion phecode
375 Disorders of lacrimal system Sense Organs 0.99 0.94 – 1.04 0.716 1523 15626 exclusion phecode
375.2 Epiphora Sense Organs 0.983 0.906 – 1.07 0.679 636 6274 exclusion phecode
376 Disorders of the orbit Sense Organs 0.903 0.679 – 1.2 0.484 52 610 exclusion phecode
377 Disorders of optic nerve and visual pathways Sense Organs 0.979 0.856 – 1.12 0.753 228 2651 exclusion phecode
377.1 Optic atrophy Sense Organs 1.03 0.739 – 1.44 0.848 34 417 exclusion phecode
377.3 Optic neuritis/neuropathy Sense Organs 0.939 0.756 – 1.17 0.566 87 959 exclusion phecode
378
Strabismus and other disorders of binocular eye
Strabismus and other disorders of binocular eye movements
 Sense Organs 0.977 0.914 – 1.04 0.483 958 10370 exclusion phecode
378.1 Strabismus (not specified as paralytic) Sense Organs 0.952 0.878 – 1.03 0.228 651 6823 exclusion phecode
378.2 Nystagmus and other irregular eye movements Sense Organs 1.02 0.849 – 1.22 0.858 125 1501 exclusion phecode
378.5 Paralytic strabismus Sense Organs 1.13 0.971 – 1.32 0.112 171 1962 exclusion phecode
379 Other disorders of eye Sense Organs 0.973 0.933 – 1.02 0.21 2311 25287 exclusion phecode
379.2 Disorders of vitreous body Sense Organs 0.981 0.916 – 1.05 0.594 875 9435 exclusion phecode
379.3 Aphakia and other disorders of lens Sense Organs 0.966 0.908 – 1.03 0.269 1086 12029 exclusion phecode
379.4 Anomalies of pupillary function Sense Organs 1.11 0.837 – 1.48 0.46 49 522 exclusion phecode
379.5 Disorders of iris and ciliary body Sense Organs 0.993 0.877 – 1.12 0.916 262 2833 exclusion phecode
379.9 Pain, swelling or discharge of eye Sense Organs 0.979 0.802 – 1.2 0.837 102 1236 exclusion phecode
380 Disorders of external ear Sense Organs 1.05 0.95 – 1.15 0.36 448 4445 exclusion phecode
380.1 Otitis externa Sense Organs 1.14 1.02 – 1.27 0.0219 342 3761 exclusion phecode
380.4 Impacted cerumen Sense Organs 1.01 0.895 – 1.15 0.839 250 2575 exclusion phecode
381 Otitis media and Eustachian tube disorders Sense Organs 1.01 0.955 – 1.06 0.767 1414 15684 exclusion phecode
381.1 Otitis media Sense Organs 1.01 0.951 – 1.07 0.757 1156 12856 exclusion phecode
381.11 Suppurative and unspecified otitis media Sense Organs 1.01 0.93 – 1.1 0.769 553 6278 exclusion phecode
381.2 Eustachian tube disorders Sense Organs 0.991 0.833 – 1.18 0.918 135 1457 exclusion phecode
381.3 Mastoiditis & related conditions Sense Organs 1.08 0.892 – 1.31 0.434 113 1243 exclusion phecode
381.9 Otorrhea Sense Organs 0.98 0.843 – 1.14 0.788 185 2030 exclusion phecode
382 Otalgia Sense Organs 1.14 0.99 – 1.3 0.0685 219 2306 exclusion phecode
383 Otosclerosis Sense Organs 1.04 0.914 – 1.19 0.522 232 2353 exclusion phecode
384 Other disorders of tympanic membrane Sense Organs 0.993 0.928 – 1.06 0.842 919 9595 exclusion phecode
384.4 Perforation of tympanic membrane Sense Organs 0.989 0.916 – 1.07 0.774 732 7653 exclusion phecode
385 Other disorders of middle ear and mastoid Sense Organs 1.06 0.969 – 1.16 0.205 527 5736 exclusion phecode
385.3 Cholesteatoma Sense Organs 1.04 0.937 – 1.15 0.475 400 4423 exclusion phecode
385.5
Tympanosclerosis and middle ear disease related
Tympanosclerosis and middle ear disease related to otitis media
 Sense Organs 1.13 0.971 – 1.32 0.113 170 1806 exclusion phecode
386
Vertiginous syndromes and other disorders of
Vertiginous syndromes and other disorders of vestibular system
 Sense Organs 1.09 1.03 – 1.16 0.00351 1156 12518 exclusion phecode
386.1 Meniere's disease Sense Organs 1.18 1.06 – 1.31 0.00179 369 4126 exclusion phecode
386.2 Peripheral or central vertigo Sense Organs 1.04 0.912 – 1.18 0.577 250 2655 exclusion phecode
386.3 Labyrinthitis Sense Organs 1.05 0.963 – 1.15 0.258 515 5560 exclusion phecode
386.9
Dizziness and giddiness (Light-headedness and
Dizziness and giddiness (Light-headedness and vertigo)
 Sense Organs 1.05 1.01 – 1.09 0.0144 2850 32587 exclusion phecode
388 Other disorders of ear Sense Organs 1.13 0.958 – 1.34 0.145 141 1463 exclusion phecode
389 Hearing loss Sense Organs 1.03 0.988 – 1.07 0.17 2628 29264 exclusion phecode
389.1 Sensorineural hearing loss Sense Organs 1.01 0.895 – 1.13 0.912 296 3179 exclusion phecode
389.2 Conductive hearing loss Sense Organs 0.971 0.862 – 1.09 0.633 296 3354 exclusion phecode
389.4 Tinnitus Sense Organs 0.953 0.85 – 1.07 0.411 336 3644 exclusion phecode
394 Rheumatic disease of the heart valves Circulatory System 1.05 1.01 – 1.09 0.011 2638 32790 exclusion phecode
394.2 Mitral valve disease Circulatory System 1.07 1.02 – 1.12 0.00994 1639 20116 exclusion phecode
394.3 Aortic valve disease Circulatory System 1.06 0.981 – 1.15 0.14 661 8535 exclusion phecode
394.7 Disease of tricuspid valve Circulatory System 1.07 0.981 – 1.16 0.129 555 7030 exclusion phecode
395 Heart valve disorders Circulatory System 1.07 1.03 – 1.12 0.00103 2254 28234 exclusion phecode
395.1 Nonrheumatic mitral valve disorders Circulatory System 1.07 1.02 – 1.13 0.0055 1586 19409 exclusion phecode
395.2 Nonrheumatic aortic valve disorders Circulatory System 1.2 1.01 – 1.43 0.0355 132 1822 exclusion phecode
395.3 Nonrheumatic tricuspid valve disorders Circulatory System 1.07 0.823 – 1.4 0.608 57 709 exclusion phecode
395.4 Nonrheumatic pulmonary valve disorders Circulatory System 0.932 0.703 – 1.24 0.623 51 657 exclusion phecode
395.6 Heart valve replaced Circulatory System 1.06 0.988 – 1.14 0.103 743 9813 exclusion phecode
396 Abnormal heart sounds Circulatory System 1.01 0.939 – 1.1 0.71 700 7655 exclusion phecode
401 Hypertension Circulatory System 1.04 1.03 – 1.05 1.97e-12 43185 207901 exclusion phecode
401.1 Essential hypertension Circulatory System 1.04 1.03 – 1.05 2.07e-12 43131 207712 exclusion phecode
401.2 Hypertensive heart and/or renal disease Circulatory System 1.08 0.978 – 1.2 0.126 349 13252 exclusion phecode
401.21 Hypertensive heart disease Circulatory System 1.03 0.885 – 1.21 0.674 157 2564 exclusion phecode
401.22 Hypertensive chronic kidney disease Circulatory System 1.12 0.973 – 1.28 0.117 192 10832 exclusion phecode
401.3 Other hypertensive complications Circulatory System 1.25 0.893 – 1.75 0.194 29 1048 exclusion phecode
402
Elevated blood pressure reading without
Elevated blood pressure reading without diagnosis of hypertension
 Circulatory System 1.04 0.976 – 1.12 0.209 908 10889 exclusion phecode
411 Ischemic Heart Disease Circulatory System 1.02 1.01 – 1.04 0.0043 17437 150784 exclusion phecode
411.1 Unstable angina (intermediate coronary syndrome) Circulatory System 1.04 1.01 – 1.08 0.025 2818 35061 exclusion phecode
411.2 Myocardial infarction Circulatory System 1.03 1 – 1.06 0.025 6320 76419 exclusion phecode
411.3 Angina pectoris Circulatory System 1 0.982 – 1.03 0.734 8723 98965 exclusion phecode
411.4 Coronary atherosclerosis Circulatory System 1.02 1 – 1.04 0.0281 11218 107549 exclusion phecode
411.41 Aneurysm and dissection of heart Circulatory System 1 0.908 – 1.1 0.974 424 4851 exclusion phecode
411.8
Other chronic ischemic heart disease
Other chronic ischemic heart disease, unspecified
 Circulatory System 1.02 1 – 1.05 0.0508 7773 89870 exclusion phecode
411.9
Other acute and subacute forms of ischemic
Other acute and subacute forms of ischemic heart disease
 Circulatory System 1.01 0.938 – 1.09 0.775 695 8291 exclusion phecode
414 Other forms of chronic heart disease Circulatory System 0.983 0.919 – 1.05 0.623 879 12319 exclusion phecode
414.2 ASCVD Circulatory System 1.29 0.942 – 1.76 0.112 38 477 exclusion phecode
415 Pulmonary heart disease Circulatory System 1.04 1 – 1.09 0.0524 2401 31183 exclusion phecode
415.11 Pulmonary embolism and infarction, acute Circulatory System 0.919 0.687 – 1.23 0.568 44 513 exclusion phecode
415.2 Chronic pulmonary heart disease Circulatory System 1.14 1.01 – 1.29 0.0327 266 4029 exclusion phecode
415.21 Primary pulmonary hypertension Circulatory System 1.08 0.939 – 1.25 0.269 197 3027 exclusion phecode
416 Cardiomegaly Circulatory System 1.03 0.971 – 1.09 0.35 1300 17990 exclusion phecode
418 Nonspecific chest pain Circulatory System 1.03 1.02 – 1.05 7.72e-05 18523 198416 exclusion phecode
418.1 Precordial pain Circulatory System 1.03 0.986 – 1.07 0.196 2284 25880 exclusion phecode
420 Carditis Circulatory System 1.07 1.01 – 1.13 0.0263 1212 14499 exclusion phecode
420.1 Myocarditis Circulatory System 1.01 0.799 – 1.27 0.943 74 906 exclusion phecode
420.2 Pericarditis Circulatory System 1.1 1.02 – 1.18 0.0085 783 9266 exclusion phecode
420.21 Acute pericarditis Circulatory System 1.05 0.895 – 1.24 0.533 152 1553 exclusion phecode
420.22 Chronic pericarditis Circulatory System 1.17 0.914 – 1.49 0.216 62 736 exclusion phecode
420.3 Endocarditis Circulatory System 1.04 0.937 – 1.15 0.493 400 4851 exclusion phecode
425 Cardiomyopathy Circulatory System 1.04 0.961 – 1.13 0.315 608 8768 exclusion phecode
425.1 Primary/intrinsic cardiomyopathies Circulatory System 1.03 0.944 – 1.11 0.551 596 8515 exclusion phecode
425.11 Hypertrophic obstructive cardiomyopathy Circulatory System 1.04 0.816 – 1.32 0.756 68 931 exclusion phecode
425.12 Other hypertrophic cardiomyopathy Circulatory System 1.02 0.825 – 1.27 0.839 89 1171 exclusion phecode
425.8 Other cardiomyopathy Circulatory System 1.48 1.06 – 2.08 0.0227 28 403 exclusion phecode
426 Cardiac conduction disorders Circulatory System 0.99 0.958 – 1.02 0.554 3814 46144 exclusion phecode
426.2 Atrioventricular [AV] block Circulatory System 0.951 0.895 – 1.01 0.101 1125 13826 exclusion phecode
426.21 First degree AV block Circulatory System 0.947 0.867 – 1.03 0.228 527 6397 exclusion phecode
426.23 Second degree AV block Circulatory System 0.974 0.861 – 1.1 0.678 268 2957 exclusion phecode
426.24 Atrioventricular block, complete Circulatory System 0.983 0.874 – 1.1 0.77 289 3853 exclusion phecode
426.25 Other heart block Circulatory System 1.04 0.818 – 1.31 0.772 75 868 exclusion phecode
426.3 Bundle branch block Circulatory System 1.01 0.959 – 1.05 0.822 1850 22379 exclusion phecode
426.31 Right bundle branch block Circulatory System 1.01 0.943 – 1.08 0.758 840 10047 exclusion phecode
426.32 Left bundle branch block Circulatory System 0.995 0.932 – 1.06 0.87 947 11678 exclusion phecode
426.4 Anomalous atrioventricular excitation Circulatory System 0.979 0.834 – 1.15 0.795 163 1747 exclusion phecode
426.8 Other cardiac conduction disorders Circulatory System 1.2 0.867 – 1.65 0.274 38 404 exclusion phecode
426.9 Cardiac pacemaker/device in situ Circulatory System 1 0.947 – 1.06 0.928 1258 16287 exclusion phecode
426.91 Cardiac pacemaker in situ Circulatory System 0.995 0.937 – 1.06 0.864 1155 14951 exclusion phecode
427 Cardiac dysrhythmias Circulatory System 1.01 0.988 – 1.02 0.546 14168 146668 exclusion phecode
427.1 Paroxysmal tachycardia, unspecified Circulatory System 1.01 0.968 – 1.06 0.583 1998 22708 exclusion phecode
427.11 Paroxysmal supraventricular tachycardia Circulatory System 1.01 0.955 – 1.06 0.822 1538 16947 exclusion phecode
427.12 Paroxysmal ventricular tachycardia Circulatory System 0.98 0.894 – 1.07 0.656 501 6314 exclusion phecode
427.2 Atrial fibrillation and flutter Circulatory System 1.01 0.985 – 1.03 0.496 7861 90141 exclusion phecode
427.3 Other specified cardiac dysrhythmias Circulatory System 0.99 0.945 – 1.04 0.67 1921 22082 exclusion phecode
427.4 Cardiac arrest and ventricular fibrillation Circulatory System 0.969 0.892 – 1.05 0.45 591 8043 exclusion phecode
427.41 Ventricular fibrillation and flutter Circulatory System 0.947 0.819 – 1.09 0.46 190 2342 exclusion phecode
427.42 Cardiac arrest Circulatory System 0.984 0.898 – 1.08 0.736 476 6663 exclusion phecode
427.5 Arrhythmia (cardiac) NOS Circulatory System 1.01 0.93 – 1.1 0.775 554 6551 exclusion phecode
427.6 Premature beats Circulatory System 1.06 0.946 – 1.18 0.331 333 3786 exclusion phecode
427.61 Supraventricular premature beats Circulatory System 0.883 0.694 – 1.12 0.314 73 831 exclusion phecode
427.7 Tachycardia NOS Circulatory System 0.998 0.943 – 1.06 0.938 1309 15806 exclusion phecode
427.8 Sinoatrial node dysfunction (Bradycardia) Circulatory System 1.07 0.94 – 1.21 0.318 247 2726 exclusion phecode
427.9 Palpitations Circulatory System 1 0.964 – 1.04 0.886 2672 28419 exclusion phecode
428 Congestive heart failure; nonhypertensive Circulatory System 1.08 1.04 – 1.13 8.27e-05 2359 36584 exclusion phecode
428.1 Congestive heart failure (CHF) NOS Circulatory System 1.08 1.01 – 1.17 0.0318 713 13567 exclusion phecode
428.2 Heart failure NOS Circulatory System 1.08 1.03 – 1.13 0.00125 1894 29081 exclusion phecode
429
Ill-defined descriptions and complications of
Ill-defined descriptions and complications of heart disease
 Circulatory System 1.05 0.954 – 1.15 0.329 462 5073 exclusion phecode
429.1 Heart transplant/surgery Circulatory System 0.823 0.514 – 1.32 0.418 19 447 exclusion phecode
429.2 Abnormal function study of cardiovascular system Circulatory System 0.993 0.887 – 1.11 0.898 336 3689 exclusion phecode
429.3 Symptoms involving cardiovascular system Circulatory System 1.22 1.03 – 1.45 0.021 126 1424 exclusion phecode
430 Intracranial hemorrhage Circulatory System 1.05 0.986 – 1.11 0.133 1172 13327 exclusion phecode
430.1 Subarachnoid hemorrhage Circulatory System 1.07 0.979 – 1.16 0.138 569 6142 exclusion phecode
430.2 Intracerebral hemorrhage Circulatory System 0.982 0.891 – 1.08 0.711 439 5232 exclusion phecode
430.3 Subdural hemorrhage Circulatory System 1.09 0.93 – 1.28 0.286 150 1749 exclusion phecode
433 Cerebrovascular disease Circulatory System 1.02 0.988 – 1.05 0.256 4755 58932 exclusion phecode
433.1 Occlusion and stenosis of precerebral arteries Circulatory System 1.07 0.989 – 1.16 0.0889 603 7600 exclusion phecode
433.12 Cerebral atherosclerosis Circulatory System 1.2 1.01 – 1.43 0.0358 123 1453 exclusion phecode
433.2 Occlusion of cerebral arteries Circulatory System 0.998 0.956 – 1.04 0.935 2213 28187 exclusion phecode
433.21
Cerebral artery occlusion, with cerebral
Cerebral artery occlusion, with cerebral infarction
 Circulatory System 0.975 0.91 – 1.04 0.469 850 11261 exclusion phecode
433.3 Cerebral ischemia Circulatory System 1.05 1 – 1.11 0.0444 1585 19448 exclusion phecode
433.31 Transient cerebral ischemia Circulatory System 1.04 0.983 – 1.1 0.163 1181 14450 exclusion phecode
433.5 Cerebral aneurysm Circulatory System 1.05 0.922 – 1.19 0.477 260 2923 exclusion phecode
433.8 Late effects of cerebrovascular disease Circulatory System 1.03 0.956 – 1.12 0.395 632 8793 exclusion phecode
440 Atherosclerosis Circulatory System 0.981 0.904 – 1.07 0.649 602 8853 exclusion phecode
440.1 Atherosclerosis of renal artery Circulatory System 1.53 1.06 – 2.21 0.0223 23 734 exclusion phecode
440.2 Atherosclerosis of the extremities Circulatory System 0.96 0.865 – 1.07 0.443 365 5154 exclusion phecode
440.9 Atherosclerosis of aorta Circulatory System 0.933 0.782 – 1.11 0.439 137 1851 exclusion phecode
441 Vascular insufficiency of intestine Circulatory System 0.973 0.869 – 1.09 0.639 315 4192 exclusion phecode
441.1 Acute vascular insufficiency of intestine Circulatory System 0.861 0.723 – 1.03 0.0959 140 1944 exclusion phecode
442 Other aneurysm Circulatory System 1.05 0.981 – 1.12 0.165 871 12071 exclusion phecode
442.1 Aortic aneurysm Circulatory System 1.03 0.955 – 1.12 0.407 611 9043 exclusion phecode
442.11 Abdominal aortic aneurysm Circulatory System 1.02 0.91 – 1.14 0.768 317 5469 exclusion phecode
442.2 Aneurysm of iliac artery Circulatory System 1.45 1.06 – 1.99 0.0209 33 605 exclusion phecode
442.3 Aneurysm of artery of lower extremity Circulatory System 0.978 0.79 – 1.21 0.841 87 1106 exclusion phecode
442.4 Arterial dissection Circulatory System 1.34 1 – 1.78 0.0477 40 411 exclusion phecode
442.8 Aneurysm of other specified artery Circulatory System 1.06 0.887 – 1.27 0.523 121 1440 exclusion phecode
443 Peripheral vascular disease Circulatory System 1.01 0.963 – 1.06 0.729 1934 26801 exclusion phecode
443.1 Raynaud's syndrome Circulatory System 1.02 0.943 – 1.09 0.675 753 8551 exclusion phecode
443.7
Peripheral angiopathy in diseases classified
Peripheral angiopathy in diseases classified elsewhere
 Circulatory System 1.09 0.907 – 1.31 0.362 111 2583 exclusion phecode
443.8 Other specified peripheral vascular diseases Circulatory System 1 0.955 – 1.05 0.978 1857 25181 exclusion phecode
443.9 Peripheral vascular disease, unspecified Circulatory System 0.988 0.931 – 1.05 0.688 1122 16871 exclusion phecode
444 Arterial embolism and thrombosis Circulatory System 1.02 0.927 – 1.13 0.664 423 6204 exclusion phecode
444.1
Arterial embolism and thrombosis of lower
Arterial embolism and thrombosis of lower extremity artery
 Circulatory System 1.09 0.963 – 1.24 0.168 236 3651 exclusion phecode
446 Polyarteritis nodosa and allied conditions Circulatory System 1.13 1.03 – 1.25 0.0137 395 5738 exclusion phecode
446.4 Wegener's granulomatosis Circulatory System 1.2 0.977 – 1.47 0.0824 81 1295 exclusion phecode
446.5 Giant cell arteritis Circulatory System 1.16 1.01 – 1.34 0.0319 206 2622 exclusion phecode
446.9 Arteritis NOS Circulatory System 1.13 0.931 – 1.36 0.22 106 1715 exclusion phecode
447 Other disorders of arteries and arterioles Circulatory System 1.01 0.933 – 1.1 0.778 621 8868 exclusion phecode
447.1 Stricture of artery Circulatory System 1 0.906 – 1.11 0.959 397 5654 exclusion phecode
448 Disease of capillaries Circulatory System 1.01 0.82 – 1.26 0.892 86 1027 exclusion phecode
450 Noninfectious disorders of lymphatic channels Circulatory System 1.01 0.915 – 1.12 0.786 381 5156 exclusion phecode
451 Phlebitis and thrombophlebitis Circulatory System 1.03 0.992 – 1.08 0.113 2252 27957 exclusion phecode
451.2
Phlebitis and thrombophlebitis of lower
Phlebitis and thrombophlebitis of lower extremities
 Circulatory System 1.05 1 – 1.09 0.0475 2088 25960 exclusion phecode
452 Other venous embolism and thrombosis Circulatory System 0.972 0.863 – 1.09 0.633 305 4118 exclusion phecode
454 Varicose veins Circulatory System 1.01 0.988 – 1.03 0.365 8006 83774 exclusion phecode
454.1 Varicose veins of lower extremity Circulatory System 1.01 0.991 – 1.04 0.247 8287 85950 exclusion phecode
454.11 Varicose veins of lower extremity, symptomtic Circulatory System 0.926 0.828 – 1.04 0.176 338 4442 exclusion phecode
455 Hemorrhoids Circulatory System 1.01 0.995 – 1.03 0.198 16487 171594 exclusion phecode
456 Chronic venous insufficiency [CVI] Circulatory System 1.08 0.876 – 1.34 0.463 85 1265 exclusion phecode
457
Encounter for long-term (current) use of
Encounter for long-term (current) use of anticoagulants, antithrombotics, aspirin
 Circulatory System 1.03 0.812 – 1.32 0.783 69 663 exclusion phecode
458 Hypotension Circulatory System 1.02 0.987 – 1.06 0.208 3122 40224 exclusion phecode
458.1 Orthostatic hypotension Circulatory System 1.01 0.931 – 1.09 0.89 676 8957 exclusion phecode
458.2 Iatrogenic hypotension Circulatory System 1.07 0.889 – 1.29 0.469 118 1585 exclusion phecode
458.9 Hypotension NOS Circulatory System 1.02 0.971 – 1.07 0.475 1883 24554 exclusion phecode
459 Other disorders of circulatory system Circulatory System 1.02 0.997 – 1.04 0.0929 8927 112673 exclusion phecode
459.1 Hemorrhage NOS Circulatory System 0.878 0.694 – 1.11 0.279 74 993 exclusion phecode
459.9 Circulatory disease NEC Circulatory System 1.02 0.999 – 1.04 0.0588 8849 111669 exclusion phecode
464 Acute sinusitis Respiratory 1.12 0.936 – 1.33 0.222 131 1476 exclusion phecode
465
Acute upper respiratory infections of multiple
Acute upper respiratory infections of multiple or unspecified sites
 Respiratory 1.01 0.962 – 1.07 0.603 1510 16828 exclusion phecode
465.2 Acute pharyngitis Respiratory 1.09 0.999 – 1.19 0.0531 553 6196 exclusion phecode
465.4 Acute laryngitis and tracheitis Respiratory 1 0.829 – 1.22 0.965 110 1204 exclusion phecode
470 Septal Deviations/Turbinate Hypertrophy Respiratory 1.04 1 – 1.07 0.0334 3440 34890 exclusion phecode
471 Nasal polyps Respiratory 1.04 0.995 – 1.08 0.0854 2359 23487 exclusion phecode
472 Chronic pharyngitis and nasopharyngitis Respiratory 1.02 0.943 – 1.1 0.634 694 7120 exclusion phecode
473 Diseases of the larynx and vocal cords Respiratory 1.02 0.968 – 1.07 0.501 1688 18166 exclusion phecode
473.1 Chronic laryngitis Respiratory 0.954 0.742 – 1.23 0.715 64 747 exclusion phecode
473.3 Paralysis/spasm of vocal cords or larynx Respiratory 1.01 0.869 – 1.18 0.869 172 1889 exclusion phecode
473.4 Voice disturbance Respiratory 0.991 0.917 – 1.07 0.812 706 7600 exclusion phecode
474 Acute and chronic tonsillitis Respiratory 1.03 0.971 – 1.08 0.362 1361 14138 exclusion phecode
474.1 Acute tonsillitis Respiratory 1.08 0.981 – 1.19 0.115 426 4455 exclusion phecode
474.2 Chronic tonsillitis and adenoiditis Respiratory 1.01 0.939 – 1.08 0.839 868 8975 exclusion phecode
475 Chronic sinusitis Respiratory 1.02 0.975 – 1.07 0.353 1842 19122 exclusion phecode
476 Allergic rhinitis Respiratory 0.965 0.896 – 1.04 0.34 804 7930 exclusion phecode
477 Epistaxis or throat hemorrhage Respiratory 1.02 0.964 – 1.07 0.543 1468 16711 exclusion phecode
478 Throat pain Respiratory 1.13 1 – 1.28 0.0437 269 2775 exclusion phecode
479 Other upper respiratory disease Respiratory 1.03 0.992 – 1.07 0.123 2863 29922 exclusion phecode
480 Pneumonia Respiratory 1.03 1 – 1.06 0.0279 5640 71497 exclusion phecode
480.1 Bacterial pneumonia Respiratory 1.04 1.01 – 1.08 0.018 3627 46061 exclusion phecode
480.11 Pneumococcal pneumonia Respiratory 1.05 1.01 – 1.08 0.0119 3210 40833 exclusion phecode
480.12 Pseudomonal pneumonia Respiratory 0.995 0.749 – 1.32 0.975 46 634 exclusion phecode
480.2 Viral pneumonia Respiratory 0.827 0.594 – 1.15 0.263 39 522 exclusion phecode
480.3 Pneumonia due to fungus (mycoses) Respiratory 1.22 0.912 – 1.64 0.179 42 678 exclusion phecode
480.5 Bronchopneumonia and lung abscess Respiratory 0.957 0.866 – 1.06 0.391 423 5257 exclusion phecode
481 Influenza Respiratory 1.04 0.901 – 1.2 0.584 191 2422 exclusion phecode
483 Acute bronchitis and bronchiolitis Respiratory 1.13 0.932 – 1.37 0.213 116 1405 exclusion phecode
495 Asthma Respiratory 1.02 1 – 1.03 0.0498 17338 187928 exclusion phecode
495.2 Asthma with exacerbation Respiratory 0.9 0.767 – 1.06 0.199 164 1912 exclusion phecode
496 Chronic airway obstruction Respiratory 1.04 1.01 – 1.07 0.00591 5308 69214 exclusion phecode
496.1 Emphysema Respiratory 1.05 0.98 – 1.12 0.168 851 11564 exclusion phecode
496.2 Chronic bronchitis Respiratory 1.07 1.02 – 1.13 0.0117 1317 19655 exclusion phecode
496.21 Obstructive chronic bronchitis Respiratory 1.07 1.01 – 1.14 0.0172 1184 17996 exclusion phecode
496.3 Bronchiectasis Respiratory 0.992 0.934 – 1.05 0.796 1112 13006 exclusion phecode
497 Bronchitis Respiratory 0.918 0.82 – 1.03 0.142 345 4518 exclusion phecode
500 Lung disease due to external agents Respiratory 1.04 0.907 – 1.2 0.548 190 2563 exclusion phecode
500.1 Extrinsic allergic alveolitis Respiratory 1.07 0.773 – 1.48 0.69 37 557 exclusion phecode
500.2 Pneumoconiosis Respiratory 1.04 0.859 – 1.25 0.7 105 1418 exclusion phecode
501 Pneumonitis due to inhalation of food or vomitus Respiratory 1.07 0.952 – 1.19 0.27 319 4401 exclusion phecode
502 Postinflammatory pulmonary fibrosis Respiratory 1.11 1.01 – 1.22 0.0298 411 6032 exclusion phecode
503 Pulmonary congestion and hypostasis Respiratory 0.884 0.761 – 1.03 0.105 188 3519 exclusion phecode
504 Other alveolar and parietoalveolar pneumonopathy Respiratory 1.33 1.13 – 1.56 0.000543 142 2260 exclusion phecode
505 Other pulmonary inflamation or edema Respiratory 1.02 0.725 – 1.43 0.921 34 435 exclusion phecode
506 Empyema and pneumothorax Respiratory 1.05 0.972 – 1.14 0.213 651 8026 exclusion phecode
507 Pleurisy; pleural effusion Respiratory 1 0.969 – 1.04 0.879 3569 43880 exclusion phecode
508
Pulmonary collapse; interstitial and
Pulmonary collapse; interstitial and compensatory emphysema
 Respiratory 0.992 0.934 – 1.05 0.801 1123 13891 exclusion phecode
509 Respiratory failure, insufficiency, arrest Respiratory 1.04 0.983 – 1.1 0.173 1185 17527 exclusion phecode
509.1 Respiratory failure Respiratory 1.06 0.994 – 1.13 0.0771 923 13859 exclusion phecode
509.2 Respiratory insufficiency Respiratory 1.06 0.991 – 1.14 0.0865 807 12198 exclusion phecode
509.5 Respiratory arrest Respiratory 1.16 0.924 – 1.45 0.201 74 1008 exclusion phecode
509.8
Dependence on respirator [Ventilator] or
Dependence on respirator [Ventilator] or supplemental oxygen
 Respiratory 1 0.866 – 1.16 0.965 184 2579 exclusion phecode
510 Other diseases of lung Respiratory 1.16 1.06 – 1.28 0.00194 432 5174 exclusion phecode
512 Other symptoms of respiratory system Respiratory 1.05 1.02 – 1.08 0.000304 5300 64335 exclusion phecode
512.1 Wheezing Respiratory 1.08 0.906 – 1.3 0.376 126 1550 exclusion phecode
512.2 Painful respiration Respiratory 1.2 1.01 – 1.43 0.0388 140 1523 exclusion phecode
512.7 Shortness of breath Respiratory 1.05 1.01 – 1.09 0.00541 3323 41531 exclusion phecode
512.8 Cough Respiratory 1.06 1.01 – 1.11 0.0187 1711 20522 exclusion phecode
512.9 Other dyspnea Respiratory 1.02 0.934 – 1.11 0.659 532 6453 exclusion phecode
513 Respiratory abnormalities Respiratory 0.994 0.889 – 1.11 0.915 344 4276 exclusion phecode
513.3 Hypoventilation Respiratory 1.12 0.785 – 1.6 0.532 31 572 exclusion phecode
513.4 Hyperventilation Respiratory 0.913 0.776 – 1.07 0.272 173 2037 exclusion phecode
513.8 Disorders of diaphragm Respiratory 1.1 0.893 – 1.35 0.374 94 1002 exclusion phecode
514 Abnormal findings examination of lungs Respiratory 1.07 1.01 – 1.12 0.0227 1360 16815 exclusion phecode
516 Abnormal sputum Respiratory 1.03 0.976 – 1.1 0.255 1221 14739 exclusion phecode
516.1 Hemoptysis Respiratory 1.03 0.975 – 1.1 0.262 1196 14347 exclusion phecode
519
Other diseases of respiratory system, not
Other diseases of respiratory system, not elsewhere classified
 Respiratory 1.03 1 – 1.06 0.0394 5349 66112 exclusion phecode
519.2 Respiratory complications Respiratory 1.09 0.929 – 1.28 0.284 149 2197 exclusion phecode
519.8 Other diseases of respiratory system, NEC Respiratory 1.03 0.997 – 1.06 0.0778 5049 62577 exclusion phecode
519.9
Symptoms involving respiratory system and other
Symptoms involving respiratory system and other chest symptoms
 Respiratory 1.03 0.894 – 1.18 0.713 216 2189 exclusion phecode
520 Disorders of tooth development Digestive 1.03 0.978 – 1.08 0.271 1587 16220 exclusion phecode
520.1 Hereditary disturbances in tooth structure Digestive 0.988 0.696 – 1.4 0.948 33 402 exclusion phecode
520.2 Disturbances in tooth eruption Digestive 1 0.954 – 1.05 0.993 1872 18920 exclusion phecode
521 Diseases of hard tissues of teeth Digestive 1.01 0.968 – 1.06 0.579 1978 22781 exclusion phecode
521.1 Dental caries Digestive 1.01 0.964 – 1.06 0.707 1980 22849 exclusion phecode
522 Diseases of pulp and periapical tissues Digestive 1.02 0.96 – 1.08 0.579 1276 13546 exclusion phecode
522.5 Periapical abscess Digestive 1.04 0.966 – 1.11 0.316 834 8939 exclusion phecode
523 Gingival and periodontal diseases Digestive 1.06 1 – 1.13 0.0474 1208 12891 exclusion phecode
523.1 Gingivitis Digestive 1.02 0.812 – 1.28 0.859 73 795 exclusion phecode
523.3 Periodontitis (acute or chronic) Digestive 1.07 1 – 1.15 0.0454 859 9141 exclusion phecode
523.31 Acute periodontitis Digestive 1.04 0.95 – 1.14 0.385 499 5333 exclusion phecode
523.32 Chronic periodontitis Digestive 1.11 1 – 1.23 0.0454 405 4296 exclusion phecode
524 Dentofacial anomalies, including malocclusion Digestive 1.04 0.914 – 1.18 0.561 250 2629 exclusion phecode
524.3 Anomalies of tooth position/malocclusion Digestive 1 0.875 – 1.14 0.99 230 2442 exclusion phecode
525
Other diseases of the teeth and supporting
Other diseases of the teeth and supporting structures
 Digestive 0.989 0.942 – 1.04 0.653 1776 19685 exclusion phecode
525.2 Atrophy of edentulous alveolar ridge Digestive 1.21 0.928 – 1.58 0.159 55 521 exclusion phecode
526 Diseases of the jaws Digestive 1.04 0.965 – 1.13 0.283 657 7001 exclusion phecode
526.1 Cysts of the jaws Digestive 0.943 0.825 – 1.08 0.391 234 2404 exclusion phecode
526.3 Anomalies of jaw size/symmetry Digestive 1.11 0.833 – 1.47 0.484 49 473 exclusion phecode
526.4 Temporomandibular joint disorders Digestive 1.12 0.965 – 1.31 0.132 168 1904 exclusion phecode
526.41 Temporomandibular joint disorder, unspecified Digestive 1.13 0.965 – 1.32 0.13 164 1846 exclusion phecode
526.5 Inflammatory conditions of jaw Digestive 1.12 0.879 – 1.41 0.37 75 816 exclusion phecode
526.9 Jaw disease NOS Digestive 1.02 0.864 – 1.21 0.808 158 1726 exclusion phecode
527 Diseases of the salivary glands Digestive 1.01 0.919 – 1.11 0.831 455 5107 exclusion phecode
527.1 Hypertrophy of salivary gland Digestive 1.09 0.838 – 1.43 0.513 54 601 exclusion phecode
527.2 Sialoadenitis Digestive 0.935 0.819 – 1.07 0.319 240 2739 exclusion phecode
527.7 Disturbance of salivary secretion Digestive 1.01 0.745 – 1.38 0.93 42 460 exclusion phecode
527.8 Other specified diseases of the salivary glands Digestive 0.958 0.771 – 1.19 0.698 84 875 exclusion phecode
528
Diseases of the oral soft tissues, excluding
Diseases of the oral soft tissues, excluding lesions specific for gingiva and tongue
 Digestive 0.998 0.959 – 1.04 0.935 2634 28527 exclusion phecode
528.1 Stomatitis and mucositis Digestive 1.08 0.962 – 1.21 0.195 301 3440 exclusion phecode
528.11 Stomatitis and mucositis (ulcerative) Digestive 1.06 0.934 – 1.2 0.363 248 2842 exclusion phecode
528.12 Oral aphthae Digestive 1.2 0.918 – 1.56 0.186 56 628 exclusion phecode
528.3 Cellulitis and abscess of oral soft tissues Digestive 1.15 0.959 – 1.39 0.13 114 1341 exclusion phecode
528.4 Cysts of oral soft tissues Digestive 1.01 0.814 – 1.26 0.916 90 909 exclusion phecode
528.41 Cyst of the salivary gland Digestive 1.01 0.785 – 1.31 0.922 65 703 exclusion phecode
528.5 Diseases of lips Digestive 1.03 0.934 – 1.13 0.595 474 5001 exclusion phecode
528.6 Leukoplakia of oral mucosa Digestive 0.814 0.701 – 0.944 0.00663 194 2174 exclusion phecode
528.7 Sialolithiasis Digestive 0.989 0.863 – 1.13 0.873 219 2313 exclusion phecode
529 Diseases and other conditions of the tongue Digestive 1.02 0.95 – 1.09 0.587 829 9018 exclusion phecode
529.1 Glossitis Digestive 1.16 1 – 1.35 0.045 186 2166 exclusion phecode
530 Diseases of esophagus Digestive 1.03 1.01 – 1.04 0.000118 21728 206908 exclusion phecode
530.1 Esophagitis, GERD and related diseases Digestive 1.03 1.02 – 1.05 2.08e-05 20403 201209 exclusion phecode
530.11 GERD Digestive 1.03 1.02 – 1.05 0.000104 14956 164974 exclusion phecode
530.12 Ulcer of esophagus Digestive 1.06 1.03 – 1.1 0.000698 3155 35906 exclusion phecode
530.14 Reflux esophagitis Digestive 1.05 1.02 – 1.07 0.000165 6827 75648 exclusion phecode
530.2 Esophageal bleeding (varices/hemorrhage) Digestive 1 0.939 – 1.07 0.925 943 11936 exclusion phecode
530.3 Stricture and stenosis of esophagus Digestive 1.04 0.981 – 1.1 0.19 1178 12933 exclusion phecode
530.5 Disorders of esophageal motility Digestive 0.983 0.888 – 1.09 0.739 399 4577 exclusion phecode
530.6 Diverticulum of esophagus, acquired Digestive 1.1 0.907 – 1.33 0.332 101 1024 exclusion phecode
530.7 Gastroesophageal laceration-hemorrhage syndrome Digestive 0.975 0.849 – 1.12 0.723 215 2522 exclusion phecode
530.9 Heartburn Digestive 1.01 0.962 – 1.07 0.585 1495 15580 exclusion phecode
531 Peptic ulcer (excl. esophageal) Digestive 1.01 0.975 – 1.04 0.714 4226 49668 exclusion phecode
531.1 Hemorrhage from gastrointestinal ulcer Digestive 0.985 0.884 – 1.1 0.786 352 4319 exclusion phecode
531.2 Gastric ulcer Digestive 0.998 0.958 – 1.04 0.935 2423 28820 exclusion phecode
531.3 Duodenal ulcer Digestive 1.01 0.961 – 1.06 0.738 1799 20881 exclusion phecode
531.4 Peptic ulcer, site unspecified Digestive 0.967 0.849 – 1.1 0.612 239 2939 exclusion phecode
532 Dysphagia Digestive 1.01 0.98 – 1.04 0.491 4228 46637 exclusion phecode
535 Gastritis and duodenitis Digestive 1.01 0.991 – 1.02 0.426 18173 191285 exclusion phecode
535.1 Acute gastritis Digestive 0.991 0.918 – 1.07 0.813 717 8385 exclusion phecode
535.2 Atrophic gastritis Digestive 0.958 0.838 – 1.09 0.525 234 2533 exclusion phecode
535.6 Duodenitis Digestive 1.02 0.986 – 1.05 0.304 4682 54128 exclusion phecode
535.8 Other specified gastritis Digestive 1.01 0.98 – 1.04 0.576 5239 57860 exclusion phecode
535.9 Gastritis and duodenitis, NOS Digestive 1.06 0.853 – 1.32 0.596 83 858 exclusion phecode
536.8
Dyspepsia and other specified disorders of
Dyspepsia and other specified disorders of function of stomach
 Digestive 1.07 0.923 – 1.24 0.361 175 1868 exclusion phecode
537 Other disorders of stomach and duodenum Digestive 1.03 0.987 – 1.08 0.162 2045 24138 exclusion phecode
540 Appendiceal conditions Digestive 0.968 0.927 – 1.01 0.138 2266 23459 exclusion phecode
540.1 Appendicitis Digestive 0.964 0.922 – 1.01 0.102 2134 21972 exclusion phecode
540.11 Acute appendicitis Digestive 0.962 0.918 – 1.01 0.103 1944 19778 exclusion phecode
550 Abdominal hernia Digestive 1.02 1.01 – 1.03 0.00293 29510 211276 exclusion phecode
550.1 Inguinal hernia Digestive 0.997 0.977 – 1.02 0.736 10584 84628 exclusion phecode
550.2 Diaphragmatic hernia Digestive 1.03 1.02 – 1.05 8.66e-05 16946 174899 exclusion phecode
550.3 Femoral hernia Digestive 0.979 0.892 – 1.07 0.647 492 4835 exclusion phecode
550.4 Umbilical hernia Digestive 1.07 1.02 – 1.11 0.00288 2206 26237 exclusion phecode
550.5 Ventral hernia Digestive 1.03 0.982 – 1.07 0.248 2061 24752 exclusion phecode
555
Inflammatory bowel disease and other
Inflammatory bowel disease and other gastroenteritis and colitis
 Digestive 1.01 0.972 – 1.05 0.643 2931 33097 exclusion phecode
555.1 Regional enteritis Digestive 1 0.944 – 1.07 0.915 1107 13156 exclusion phecode
555.2 Ulcerative colitis Digestive 1.01 0.967 – 1.06 0.643 2119 23491 exclusion phecode
555.21 Ulcerative colitis (chronic) Digestive 1 0.904 – 1.12 0.931 381 4097 exclusion phecode
556 Ulceration of the lower GI tract Digestive 1.11 1.03 – 1.19 0.00855 693 7778 exclusion phecode
556.1 Ulceration of intestine Digestive 1.04 0.942 – 1.14 0.463 429 4916 exclusion phecode
557 Intestinal malabsorption (non-celiac) Digestive 0.998 0.864 – 1.15 0.982 198 2289 exclusion phecode
557.1 Celiac disease Digestive 0.995 0.94 – 1.05 0.865 1289 13848 exclusion phecode
558 Noninfectious gastroenteritis Digestive 1.03 1.01 – 1.05 0.00346 10139 116051 exclusion phecode
559 Ileostomy status Digestive 0.984 0.922 – 1.05 0.62 998 11716 exclusion phecode
560 Intestinal obstruction without mention of hernia Digestive 1.02 0.977 – 1.06 0.4 2534 28294 exclusion phecode
560.1 Paralytic ileus Digestive 1.01 0.901 – 1.13 0.882 318 3637 exclusion phecode
560.2 Impaction of intestine Digestive 1.09 0.939 – 1.27 0.251 165 1951 exclusion phecode
560.3 Peritoneal or intestinal adhesions Digestive 0.946 0.866 – 1.03 0.212 547 6023 exclusion phecode
560.4 Other intestinal obstruction Digestive 1 0.962 – 1.05 0.827 2181 24215 exclusion phecode
561 Symptoms involving digestive system Digestive 1.02 0.996 – 1.04 0.118 11071 118093 exclusion phecode
561.1 Diarrhea Digestive 0.996 0.886 – 1.12 0.94 307 3348 exclusion phecode
561.2 Flatulence Digestive 1.04 0.98 – 1.1 0.201 1188 12682 exclusion phecode
562 Diverticulosis and diverticulitis Digestive 1.02 1 – 1.04 0.0143 17018 154122 exclusion phecode
562.1 Diverticulosis Digestive 1.02 1 – 1.04 0.0178 16988 154070 exclusion phecode
563 Constipation Digestive 1.02 0.991 – 1.04 0.204 6720 75745 exclusion phecode
564 Functional digestive disorders Digestive 1.02 0.999 – 1.03 0.0705 14222 154657 exclusion phecode
564.1 Irritable Bowel Syndrome Digestive 1.02 0.984 – 1.05 0.314 4007 42741 exclusion phecode
564.8
Abnormal findings on exam of gastrointestinal
Abnormal findings on exam of gastrointestinal tract/ abdominal area
 Digestive 1.02 0.955 – 1.08 0.593 1036 11923 exclusion phecode
564.9 Personal history of diseases of digestive system Digestive 1.02 0.995 – 1.04 0.138 9638 108537 exclusion phecode
565 Anal and rectal conditions Digestive 0.992 0.972 – 1.01 0.429 10014 106323 exclusion phecode
565.1 Anal and rectal polyp Digestive 0.992 0.963 – 1.02 0.582 4897 51529 exclusion phecode
567 Peritonitis and retroperitoneal infections Digestive 1.01 0.921 – 1.1 0.86 519 6610 exclusion phecode
568 Other disorders of peritoneum Digestive 1.04 0.995 – 1.09 0.0832 2143 24137 exclusion phecode
568.1
Peritoneal adhesions (postoperative)
Peritoneal adhesions (postoperative) (postinfection)
 Digestive 1.04 0.995 – 1.09 0.0796 2045 22970 exclusion phecode
569 Other disorders of intestine Digestive 1.03 0.995 – 1.08 0.0844 2686 29901 exclusion phecode
569.1 Toxic gastroenteritis and colitis Digestive 1 0.814 – 1.24 0.976 94 1003 exclusion phecode
569.2 Gastrointestinal complications Digestive 1.09 0.974 – 1.22 0.136 318 3425 exclusion phecode
571 Chronic liver disease and cirrhosis Digestive 1.08 1.03 – 1.14 0.00247 1504 21458 exclusion phecode
571.5 Other chronic nonalcoholic liver disease Digestive 1.11 1.04 – 1.19 0.00141 944 12403 exclusion phecode
571.51 Cirrhosis of liver without mention of alcohol Digestive 1.09 0.838 – 1.41 0.527 55 810 exclusion phecode
571.6 Primary biliary cirrhosis Digestive 1.11 0.915 – 1.34 0.294 105 1910 exclusion phecode
571.8
Liver abscess and sequelae of chronic liver
Liver abscess and sequelae of chronic liver disease
 Digestive 1.04 0.946 – 1.15 0.405 430 6942 exclusion phecode
571.81 Portal hypertension Digestive 1.12 0.982 – 1.28 0.0909 214 3717 exclusion phecode
572 Ascites (non malignant) Digestive 1.03 0.96 – 1.1 0.432 870 11009 exclusion phecode
573 Other disorders of liver Digestive 1.04 0.973 – 1.12 0.232 842 10720 exclusion phecode
573.2 Liver replaced by transplant Digestive 0.945 0.577 – 1.55 0.823 15 719 exclusion phecode
573.3 Hepatomegaly Digestive 1.1 0.937 – 1.3 0.238 145 2103 exclusion phecode
573.5 Jaundice (not of newborn) Digestive 1.02 0.931 – 1.11 0.685 498 6264 exclusion phecode
573.7 Abnormal results of function study of liver Digestive 1.04 0.999 – 1.09 0.0572 2045 24822 exclusion phecode
573.9 Abnormal serum enzyme levels Digestive 1.08 0.9 – 1.29 0.413 118 1416 exclusion phecode
574 Cholelithiasis and cholecystitis Digestive 1.03 1.01 – 1.05 0.00264 9995 116039 exclusion phecode
574.1 Cholelithiasis Digestive 1.02 1 – 1.05 0.0291 8674 100916 exclusion phecode
574.11 Cholelithiasis with acute cholecystitis Digestive 0.97 0.906 – 1.04 0.376 915 10927 exclusion phecode
574.12 Cholelithiasis with other cholecystitis Digestive 1.05 1.01 – 1.08 0.00703 3535 40608 exclusion phecode
574.2 Calculus of bile duct Digestive 1.07 1.02 – 1.13 0.00593 1591 19218 exclusion phecode
574.3 Cholecystitis without cholelithiasis Digestive 1.03 0.976 – 1.08 0.322 1684 20184 exclusion phecode
575 Other biliary tract disease Digestive 1.02 0.983 – 1.07 0.258 2417 28197 exclusion phecode
575.1 Cholangitis Digestive 0.954 0.839 – 1.08 0.469 246 3359 exclusion phecode
575.2 Obstruction of bile duct Digestive 0.99 0.901 – 1.09 0.829 469 5513 exclusion phecode
575.6 Cholesterolosis of gallbladder Digestive 0.996 0.891 – 1.11 0.947 329 3555 exclusion phecode
575.7 Other disorders of gallbladder Digestive 1.05 0.98 – 1.12 0.164 903 10419 exclusion phecode
575.8 Other disorders of biliary tract Digestive 1.06 0.976 – 1.15 0.169 629 7533 exclusion phecode
575.9
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of biliary tract
 Digestive 1.03 0.893 – 1.18 0.701 201 2448 exclusion phecode
577 Diseases of pancreas Digestive 1.06 1.01 – 1.11 0.0296 1539 18975 exclusion phecode
577.1 Acute pancreatitis Digestive 1.06 1 – 1.13 0.0399 1156 14294 exclusion phecode
577.2 Chronic pancreatitis Digestive 0.986 0.876 – 1.11 0.819 289 3652 exclusion phecode
577.3 Cyst and pseudocyst of pancreas Digestive 1.06 0.923 – 1.21 0.415 214 2618 exclusion phecode
578 Gastrointestinal hemorrhage Digestive 1.01 0.995 – 1.03 0.166 14019 150844 exclusion phecode
578.1 Hematemesis Digestive 1.01 0.949 – 1.07 0.792 1103 13997 exclusion phecode
578.2 Blood in stool Digestive 0.994 0.944 – 1.05 0.804 1574 18437 exclusion phecode
578.8 Hemorrhage of rectum and anus Digestive 1.01 0.989 – 1.03 0.327 9164 96331 exclusion phecode
578.9 Hemorrhage of gastrointestinal tract Digestive 1 0.969 – 1.04 0.859 3559 38564 exclusion phecode
579 Other symptoms involving abdomen and pelvis Digestive 1.07 1.01 – 1.15 0.0308 915 11399 exclusion phecode
579.2 Splenomegaly Digestive 1.19 1.03 – 1.38 0.0194 164 2991 exclusion phecode
579.8 Nonspecific abnormal findings in stool contents Digestive 1.02 0.956 – 1.08 0.588 1127 11968 exclusion phecode
580 Nephritis; nephrosis; renal sclerosis Genitourinary 1.12 1 – 1.24 0.0482 320 10528 exclusion phecode
580.1 Glomerulonephritis Genitourinary 1.14 0.995 – 1.32 0.0594 189 7088 exclusion phecode
580.11 Proliferative glomerulonephritis Genitourinary 1 0.665 – 1.51 0.997 18 560 exclusion phecode
580.12 Non-proliferative glomerulonephritis Genitourinary 0.885 0.645 – 1.21 0.449 37 957 exclusion phecode
580.14 Chronic glomerulonephritis, NOS Genitourinary 1.22 1.04 – 1.43 0.0165 140 5813 exclusion phecode
580.2
Nephrotic syndrome without mention of
Nephrotic syndrome without mention of glomerulonephritis
 Genitourinary 1.05 0.875 – 1.26 0.611 113 3276 exclusion phecode
580.3
Nephritis and nephropathy without mention of
Nephritis and nephropathy without mention of glomerulonephritis
 Genitourinary 1.05 0.827 – 1.33 0.696 66 1741 exclusion phecode
580.32
Nephritis and nephropathy with pathological
Nephritis and nephropathy with pathological lesion
 Genitourinary 1.05 0.83 – 1.32 0.7 67 1798 exclusion phecode
585 Renal failure Genitourinary 1.08 1.04 – 1.13 0.00013 2224 47440 exclusion phecode
585.1 Acute renal failure Genitourinary 1.07 1.02 – 1.12 0.00585 1647 30586 exclusion phecode
585.2 Renal failure NOS Genitourinary 1.08 0.979 – 1.19 0.126 407 10013 exclusion phecode
585.3 Chronic renal failure [CKD] Genitourinary 1.1 0.999 – 1.2 0.0531 445 17878 exclusion phecode
585.31 Renal dialysis Genitourinary 1.21 0.969 – 1.52 0.092 67 3525 exclusion phecode
586 Other disorders of the kidney and ureters Genitourinary 1.03 0.983 – 1.09 0.197 1613 23513 exclusion phecode
586.1 Anatomical abnormatilies of kidney and ureters Genitourinary 1.08 0.822 – 1.42 0.575 46 1460 exclusion phecode
586.11 Small kidney Genitourinary 1.18 0.876 – 1.6 0.274 38 1242 exclusion phecode
586.2 Cyst of kidney, acquired Genitourinary 1.07 0.986 – 1.15 0.108 653 8642 exclusion phecode
586.3 Vascular disorders of kidney/hypertrophy Genitourinary 0.957 0.648 – 1.41 0.826 26 569 exclusion phecode
586.4 Stricture/obstruction of ureter Genitourinary 1.01 0.921 – 1.11 0.813 473 6532 exclusion phecode
587 Kidney replaced by transpant Genitourinary 1.08 0.752 – 1.56 0.666 24 2697 exclusion phecode
588 Disorders resulting from impaired renal function Genitourinary 0.921 0.603 – 1.41 0.704 21 735 exclusion phecode
589 Abnormal results of function study of kidney Genitourinary 0.809 0.595 – 1.1 0.174 42 808 exclusion phecode
590 Pyelonephritis Genitourinary 1.05 0.98 – 1.13 0.16 801 10146 exclusion phecode
591 Urinary tract infection Genitourinary 0.993 0.969 – 1.02 0.535 7516 88690 exclusion phecode
592 Cystitis and urethritis Genitourinary 1.02 0.976 – 1.07 0.345 1928 21171 exclusion phecode
592.1 Cystitis Genitourinary 1.01 0.967 – 1.06 0.574 1886 20769 exclusion phecode
592.11 Acute cystitis Genitourinary 0.996 0.799 – 1.24 0.969 86 944 exclusion phecode
592.12 Chronic cystitis Genitourinary 1 0.921 – 1.09 0.958 577 6386 exclusion phecode
592.13 Chronic interstitial cystitis Genitourinary 0.977 0.835 – 1.14 0.777 173 1820 exclusion phecode
592.2 Urethritis and urethral syndrome Genitourinary 1.15 0.973 – 1.37 0.0995 121 1186 exclusion phecode
593 Hematuria Genitourinary 0.986 0.966 – 1.01 0.172 10355 112993 exclusion phecode
594 Urinary calculus Genitourinary 0.98 0.949 – 1.01 0.216 3976 45158 exclusion phecode
594.1 Calculus of kidney Genitourinary 0.995 0.951 – 1.04 0.845 1936 22297 exclusion phecode
594.2 Calculus of lower urinary tract Genitourinary 0.934 0.848 – 1.03 0.17 430 5060 exclusion phecode
594.3 Calculus of ureter Genitourinary 0.981 0.931 – 1.03 0.483 1479 17012 exclusion phecode
594.8 Renal colic Genitourinary 0.991 0.937 – 1.05 0.742 1333 14789 exclusion phecode
595 Hydronephrosis Genitourinary 0.979 0.92 – 1.04 0.516 1061 13692 exclusion phecode
596 Other disorders of bladder Genitourinary 1.02 0.989 – 1.04 0.258 6147 66514 exclusion phecode
596.1 Bladder neck obstruction Genitourinary 0.987 0.93 – 1.05 0.653 1187 12461 exclusion phecode
596.5 Functional disorders of bladder Genitourinary 1.02 0.957 – 1.08 0.573 1093 12035 exclusion phecode
597 Other disorders of urethra and urinary tract Genitourinary 1.03 0.992 – 1.07 0.12 2569 27514 exclusion phecode
597.1 Urethral stricture (not specified as infectious) Genitourinary 1.03 0.987 – 1.08 0.176 2151 23144 exclusion phecode
597.2 Urinary complications NEC Genitourinary 1.05 0.772 – 1.43 0.748 38 544 exclusion phecode
598 Abnormal findings on examination of urine Genitourinary 1.02 0.978 – 1.07 0.352 2262 24317 exclusion phecode
598.9
Other nonspecific findings on examination of
Other nonspecific findings on examination of urine
 Genitourinary 1.01 0.865 – 1.19 0.861 158 2095 exclusion phecode
599 Other symptoms/disorders or the urinary system Genitourinary 1.01 0.991 – 1.03 0.342 12379 133880 exclusion phecode
599.1 Urinary obstruction Genitourinary 1.01 0.804 – 1.26 0.951 79 1139 exclusion phecode
599.2 Retention of urine Genitourinary 1.04 1.01 – 1.07 0.0181 3915 44012 exclusion phecode
599.3 Dysuria Genitourinary 1 0.931 – 1.08 0.95 767 8611 exclusion phecode
599.4 Urinary incontinence Genitourinary 1.01 0.983 – 1.04 0.519 6225 66676 exclusion phecode
599.5 Frequency of urination and polyuria Genitourinary 1.01 0.969 – 1.05 0.692 2659 28363 exclusion phecode
599.6 Oliguria and anuria Genitourinary 1.24 0.922 – 1.68 0.154 37 695 exclusion phecode
599.8 Other symptoms involving urinary system Genitourinary 0.933 0.67 – 1.3 0.682 37 432 exclusion phecode
599.9 Other abnormality of urination Genitourinary 1.04 0.983 – 1.1 0.167 1246 13115 exclusion phecode
600 Hyperplasia of prostate Genitourinary 1.01 0.984 – 1.04 0.478 6386 55946 exclusion phecode
601 Inflammatory diseases of prostate Genitourinary 1.04 0.978 – 1.1 0.228 1239 13404 exclusion phecode
601.1 Prostatitis Genitourinary 1.06 0.997 – 1.14 0.0602 935 9926 exclusion phecode
601.11 Acute prostatitis Genitourinary 0.971 0.819 – 1.15 0.733 135 1527 exclusion phecode
601.12 Chronic prostatitis Genitourinary 1.04 0.957 – 1.14 0.337 548 5689 exclusion phecode
601.3 Orchitis and epididymitis Genitourinary 1.14 0.839 – 1.55 0.403 45 421 exclusion phecode
601.4 Balanoposthitis Genitourinary 0.977 0.838 – 1.14 0.766 179 1907 exclusion phecode
601.8
Other inflammatory disorders of male genital
Other inflammatory disorders of male genital organs
 Genitourinary 1.04 0.89 – 1.22 0.623 168 2013 exclusion phecode
602 Other disorders of prostate Genitourinary 1.07 0.993 – 1.14 0.0775 787 8223 exclusion phecode
603 Other disorders of testis Genitourinary 0.967 0.915 – 1.02 0.241 1349 14624 exclusion phecode
603.1 Hydrocele Genitourinary 0.939 0.874 – 1.01 0.0848 832 8911 exclusion phecode
604 Disorders of penis Genitourinary 1.02 0.976 – 1.07 0.365 2065 22593 exclusion phecode
604.1 Redundant prepuce and phimosis/BXO Genitourinary 0.988 0.94 – 1.04 0.63 1692 18724 exclusion phecode
605 Erectile dysfunction [ED] Genitourinary 1.04 0.889 – 1.21 0.655 168 1816 exclusion phecode
608 Other disorders of male genital organs Genitourinary 1.03 0.978 – 1.08 0.289 1823 19075 exclusion phecode
609 Male infertility and abnormal spermatozoa Genitourinary 1.04 0.878 – 1.23 0.649 135 1361 exclusion phecode
609.1 Infertility, male Genitourinary 1.11 0.829 – 1.48 0.491 49 503 exclusion phecode
609.2 Abnormal spermatozoa Genitourinary 1.02 0.839 – 1.24 0.848 99 1002 exclusion phecode
610 Benign mammary dysplasias Genitourinary 0.995 0.95 – 1.04 0.819 1972 19921 exclusion phecode
610.1 Cystic mastopathy Genitourinary 0.99 0.917 – 1.07 0.792 722 7285 exclusion phecode
610.2 Fibroadenosis of breast Genitourinary 1.08 0.948 – 1.24 0.24 238 2420 exclusion phecode
610.3 Fibrosclerosis of breast Genitourinary 0.906 0.79 – 1.04 0.156 235 2364 exclusion phecode
610.4 Benign neoplasm of breast Genitourinary 0.99 0.931 – 1.05 0.757 1121 11242 exclusion phecode
610.8 Other specified benign mammary dysplasias Genitourinary 1 0.918 – 1.1 0.914 522 5394 exclusion phecode
611 Abnormal findings on mammogram or breast exam Genitourinary 1.06 1 – 1.13 0.0356 1239 12358 exclusion phecode
611.1 Abnormal mammogram Genitourinary 1.19 0.884 – 1.59 0.254 48 428 exclusion phecode
611.3 Lump or mass in breast Genitourinary 1.07 1 – 1.13 0.0358 1195 11952 exclusion phecode
612
Breast conditions, congenital or relating to
Breast conditions, congenital or relating to hormones
 Genitourinary 1 0.925 – 1.08 0.988 675 7059 exclusion phecode
612.2 Hypertrophy of breast (Gynecomastia) Genitourinary 1 0.928 – 1.09 0.907 644 6692 exclusion phecode
612.3 Congenital anomalies of breast Genitourinary 1.03 0.793 – 1.33 0.832 62 597 exclusion phecode
613 Other nonmalignant breast conditions Genitourinary 0.968 0.912 – 1.03 0.277 1213 13058 exclusion phecode
613.1 Inflammatory disease of breast Genitourinary 0.905 0.826 – 0.993 0.0348 519 5681 exclusion phecode
613.5 Mastodynia Genitourinary 0.906 0.684 – 1.2 0.491 52 617 exclusion phecode
613.7 Other signs and symptoms in breast Genitourinary 1.08 0.988 – 1.18 0.0888 543 5480 exclusion phecode
613.8 Other specified disorders of breast Genitourinary 1.01 0.891 – 1.15 0.838 252 2598 exclusion phecode
613.9 Breast disorder NOS Genitourinary – 154 1613 exclusion phecode
614 Inflammatory diseases of female pelvic organs Genitourinary 0.985 0.955 – 1.02 0.328 4555 46930 exclusion phecode
614.1
Pelvic peritoneal adhesions, female
Pelvic peritoneal adhesions, female (postoperative) (postinfection)
 Genitourinary 0.978 0.934 – 1.02 0.34 2029 21054 exclusion phecode
614.3 Pelvic inflammatory disease (PID) Genitourinary 0.974 0.899 – 1.05 0.518 674 6917 exclusion phecode
614.31 Acute inflammatory pelvic disease Genitourinary 1.12 0.821 – 1.53 0.471 50 511 exclusion phecode
614.32 Chronic inflammatory pelvic disease Genitourinary 0.989 0.885 – 1.1 0.84 335 3472 exclusion phecode
614.33 Pelvic inflammatory disease, NOS Genitourinary 0.988 0.872 – 1.12 0.852 284 2951 exclusion phecode
614.4 Inflammatory diseases of uterus, except cervix Genitourinary 1 0.875 – 1.15 0.947 219 2266 exclusion phecode
614.5
Inflammatory disease of cervix, vagina, and
Inflammatory disease of cervix, vagina, and vulva
 Genitourinary 0.986 0.942 – 1.03 0.538 2070 21159 exclusion phecode
614.51 Cervicitis and endocervicitis Genitourinary 1 0.942 – 1.07 0.912 1039 10678 exclusion phecode
614.52 Vaginitis and vulvovaginitis Genitourinary 1.02 0.91 – 1.14 0.753 334 3428 exclusion phecode
614.53 Cyst or abscess of Bartholin's gland Genitourinary 0.927 0.852 – 1.01 0.0774 632 6251 exclusion phecode
614.54 Abscess or ulceration of vulva Genitourinary 1.06 0.92 – 1.22 0.429 205 2238 exclusion phecode
615 Endometriosis Genitourinary 0.992 0.956 – 1.03 0.645 3310 33907 exclusion phecode
617
Disorders secondary to childbirth, surgery
Disorders secondary to childbirth, surgery, trauma
 Genitourinary 1.13 0.988 – 1.29 0.0746 222 2413 exclusion phecode
618 Genital prolapse Genitourinary 1.01 0.992 – 1.04 0.203 8798 89103 exclusion phecode
618.1 Prolapse of vaginal walls Genitourinary 1.02 0.993 – 1.05 0.146 5502 56218 exclusion phecode
618.2 Uterine/Uterovaginal prolapse Genitourinary 1.01 0.977 – 1.04 0.591 4144 40977 exclusion phecode
618.5 Prolapse of vaginal vault after hysterectomy Genitourinary 1.03 0.928 – 1.15 0.552 373 3802 exclusion phecode
618.6 Vaginal enterocele, congenital or acquired Genitourinary 1 0.909 – 1.1 0.992 475 5087 exclusion phecode
619 Noninflammatory female genital disorders Genitourinary 1.01 0.985 – 1.04 0.431 6911 70025 exclusion phecode
619.1
Noninflammatory disorders of ovary, fallopian
Noninflammatory disorders of ovary, fallopian tube, and broad ligament
 Genitourinary 1.03 0.946 – 1.12 0.502 582 5971 exclusion phecode
619.2 Disorders of uterus, NEC Genitourinary 0.99 0.95 – 1.03 0.622 2576 26151 exclusion phecode
619.3 Noninflammatory disorders of cervix Genitourinary 1.04 0.998 – 1.09 0.0593 2316 23245 exclusion phecode
619.4 Noninflammatory disorders of vagina Genitourinary 1.06 1 – 1.12 0.0368 1403 14196 exclusion phecode
619.5 Noninflammatory disorders of vulva and perineum Genitourinary 0.961 0.902 – 1.02 0.219 1065 10872 exclusion phecode
620 Dysplasia of female genital organs Genitourinary 1.18 0.892 – 1.55 0.248 51 574 exclusion phecode
621 Endometrial hyperplasia Genitourinary 0.975 0.908 – 1.05 0.49 819 8975 exclusion phecode
622 Polyp of female genital organs Genitourinary 0.998 0.976 – 1.02 0.884 8117 82727 exclusion phecode
622.1 Polyp of corpus uteri Genitourinary 0.99 0.964 – 1.02 0.459 5988 62113 exclusion phecode
622.2 Mucous polyp of cervix Genitourinary 1 0.963 – 1.04 0.948 2767 26862 exclusion phecode
623 Hypertrophy of female genital organs Genitourinary 1.04 0.975 – 1.11 0.236 1009 10437 exclusion phecode
624 Symptoms involving female genital tract Genitourinary 0.995 0.915 – 1.08 0.914 582 6032 exclusion phecode
624.1 Dystrophy of female genital tract Genitourinary 0.975 0.834 – 1.14 0.75 171 1815 exclusion phecode
624.2 Atrophy of female genital tract Genitourinary 1 0.895 – 1.13 0.937 320 3333 exclusion phecode
624.9 stress incontinence, female Genitourinary 1.01 0.977 – 1.04 0.601 4407 45979 exclusion phecode
625
Pain and other symptoms associated with female
Pain and other symptoms associated with female genital organs
 Genitourinary 1 0.963 – 1.05 0.838 2427 24139 exclusion phecode
625.1 Dyspareunia Genitourinary 1.03 0.962 – 1.1 0.419 990 9975 exclusion phecode
626
Disorders of menstruation and other abnormal
Disorders of menstruation and other abnormal bleeding from female genital tract
 Genitourinary 1.01 0.991 – 1.03 0.307 13511 95319 exclusion phecode
626.1 Irregular menstrual cycle/bleeding Genitourinary 1.02 0.996 – 1.04 0.112 11804 91590 exclusion phecode
626.11 Absent or infrequent menstruation Genitourinary 0.968 0.771 – 1.21 0.776 86 937 exclusion phecode
626.12 Excessive or frequent menstruation Genitourinary 1.02 1 – 1.05 0.0458 8024 77074 exclusion phecode
626.13 Irregular menstrual cycle Genitourinary 0.997 0.947 – 1.05 0.902 1612 16218 exclusion phecode
626.14 Irregular menstrual bleeding Genitourinary 1.02 0.982 – 1.06 0.332 3186 32196 exclusion phecode
626.2 Dysmenorrhea Genitourinary 0.965 0.914 – 1.02 0.199 1464 15245 exclusion phecode
626.4 Premenstrual tension syndromes Genitourinary 1.1 0.918 – 1.32 0.297 119 1378 exclusion phecode
626.8 Infertility, female Genitourinary 0.964 0.908 – 1.02 0.238 1228 12044 exclusion phecode
627 Menopausal and postmenopausal disorders Genitourinary 1.02 0.999 – 1.05 0.062 7565 79145 exclusion phecode
627.1 Postmenopausal bleeding Genitourinary 1.01 0.984 – 1.04 0.465 6532 68560 exclusion phecode
627.2 Symptomatic menopause Genitourinary 1.13 0.961 – 1.34 0.136 136 1443 exclusion phecode
627.3 Postmenopausal atrophic vaginitis Genitourinary 1.06 0.991 – 1.14 0.0882 797 8226 exclusion phecode
627.4 Premenopausal menorrhagia Genitourinary 1.12 0.979 – 1.27 0.101 241 2526 exclusion phecode
628 Ovarian cyst Genitourinary 0.993 0.96 – 1.03 0.673 3823 39143 exclusion phecode
634 Miscarriage; stillbirth Pregnancy Complications 0.973 0.943 – 1 0.0863 4734 32491 exclusion phecode
634.1 Missed abortion/Hydatidiform mole Pregnancy Complications 0.996 0.933 – 1.06 0.908 1022 10166 exclusion phecode
634.3 Ectopic pregnancy Pregnancy Complications 0.999 0.886 – 1.13 0.984 301 2930 exclusion phecode
635
Hemorrhage during pregnancy; childbirth and
Hemorrhage during pregnancy; childbirth and postpartum
 Pregnancy Complications 0.987 0.939 – 1.04 0.61 1817 15648 exclusion phecode
635.2
Antepartum hemorrhage, abruptio placentae, and
Antepartum hemorrhage, abruptio placentae, and placenta previa
 Pregnancy Complications 0.975 0.903 – 1.05 0.507 798 7773 exclusion phecode
635.3 Placenta previa and abruptio placenta Pregnancy Complications 0.993 0.934 – 1.06 0.817 1167 11078 exclusion phecode
636
Early or threatened labor; hemorrhage in early
Early or threatened labor; hemorrhage in early pregnancy
 Pregnancy Complications 1.02 0.973 – 1.07 0.432 2145 17938 exclusion phecode
636.2 Early onset of delivery Pregnancy Complications 1.02 0.938 – 1.12 0.586 563 5515 exclusion phecode
636.3 Hemorrhage in early pregnancy Pregnancy Complications 1 0.936 – 1.07 0.992 985 9563 exclusion phecode
638 Other high-risk pregnancy Pregnancy Complications 0.965 0.735 – 1.27 0.798 61 625 exclusion phecode
642
Hypertension complicating pregnancy
Hypertension complicating pregnancy, childbirth, and the puerperium
 Pregnancy Complications 0.956 0.893 – 1.02 0.193 981 10029 exclusion phecode
642.1 Preeclampsia and eclampsia Pregnancy Complications 1 0.885 – 1.14 0.95 271 2751 exclusion phecode
643 Excessive vomiting in pregnancy Pregnancy Complications 0.843 0.72 – 0.987 0.0338 185 1948 exclusion phecode
643.1 Hyperemesis gravidarum Pregnancy Complications 0.93 0.774 – 1.12 0.438 131 1363 exclusion phecode
645 Late pregnancy and failed induction Pregnancy Complications 1 0.944 – 1.07 0.887 1147 11281 exclusion phecode
646 Other complications of pregnancy NEC Pregnancy Complications 0.999 0.953 – 1.05 0.951 2016 18854 exclusion phecode
647
Infectious and parasitic complications
Infectious and parasitic complications affecting pregnancy
 Pregnancy Complications 0.94 0.725 – 1.22 0.638 59 600 exclusion phecode
647.1
Infections of genitourinary tract during
Infections of genitourinary tract during pregnancy
 Pregnancy Complications 1.07 0.942 – 1.22 0.292 258 2476 exclusion phecode
649
Other conditions or status of the mother
Other conditions or status of the mother complicating pregnancy, childbirth, or the puerperium
 Pregnancy Complications 0.901 0.732 – 1.11 0.323 103 1010 exclusion phecode
649.1
Diabetes or abnormal glucose tolerance
Diabetes or abnormal glucose tolerance complicating pregnancy
 Pregnancy Complications 0.998 0.849 – 1.17 0.979 176 1744 exclusion phecode
650 Normal delivery Pregnancy Complications 0.981 0.933 – 1.03 0.462 1772 17119 exclusion phecode
651 Multiple gestation Pregnancy Complications 0.898 0.795 – 1.02 0.0863 310 3126 exclusion phecode
652
Malposition and malpresentation of fetus or
Malposition and malpresentation of fetus or obstruction
 Pregnancy Complications 0.964 0.914 – 1.02 0.171 1590 14954 exclusion phecode
653
Problems associated with amniotic cavity and
Problems associated with amniotic cavity and membranes
 Pregnancy Complications 1 0.945 – 1.06 0.943 1281 12312 exclusion phecode
654
Other and unspecified complications of birth
Other and unspecified complications of birth; puerperium affecting management of mother
 Pregnancy Complications 1.35 1.04 – 1.74 0.0226 66 656 exclusion phecode
655
Known or suspected fetal abnormality affecting
Known or suspected fetal abnormality affecting management of mother
 Pregnancy Complications 0.982 0.949 – 1.02 0.314 3940 26537 exclusion phecode
656 Other perinatal conditions of fetus or newborn Pregnancy Complications 1.05 0.853 – 1.3 0.636 95 977 exclusion phecode
661 Fetal distress and abnormal forces of labor Pregnancy Complications 0.943 0.899 – 0.989 0.015 2086 16594 exclusion phecode
663
Umbilical cord complications during labor and
Umbilical cord complications during labor and delivery
 Pregnancy Complications 0.963 0.875 – 1.06 0.445 492 4803 exclusion phecode
665 Obstetrical/birth trauma Pregnancy Complications 0.974 0.943 – 1.01 0.11 4864 26481 exclusion phecode
669 Complications of labor and delivery NEC Pregnancy Complications 0.994 0.951 – 1.04 0.776 2333 19087 exclusion phecode
671
Venous/cerebrovascular complications embolism
Venous/cerebrovascular complications embolism in pregnancy and the puerperium
 Pregnancy Complications 0.953 0.795 – 1.14 0.606 146 1472 exclusion phecode
674 Other complications of the puerperium NEC Pregnancy Complications 1.02 0.89 – 1.16 0.825 241 2368 exclusion phecode
676
Other disorders of the breast associated with
Other disorders of the breast associated with childbirth and disorders of lactation
 Pregnancy Complications 1.06 0.793 – 1.41 0.706 58 565 exclusion phecode
679 Complications of in utero procedures Dermatologic 1.11 0.836 – 1.48 0.463 48 490 exclusion phecode
681 Superficial cellulitis and abscess Dermatologic 1.03 0.996 – 1.06 0.0854 4027 51507 exclusion phecode
681.1 Cellulitis and abscess of fingers/toes Dermatologic 0.941 0.843 – 1.05 0.277 353 4109 exclusion phecode
681.2 Cellulitis and abscess of face/neck Dermatologic 1.09 0.978 – 1.21 0.122 346 3838 exclusion phecode
681.3 Cellulitis and abscess of arm/hand Dermatologic 1.02 0.98 – 1.06 0.359 2928 38974 exclusion phecode
681.5 Cellulitis and abscess of leg, except foot Dermatologic 1.02 0.983 – 1.06 0.289 2932 39017 exclusion phecode
681.6 Cellulitis and abscess of foot, toe Dermatologic 1.02 0.983 – 1.06 0.295 2904 38675 exclusion phecode
681.7 Cellulitis and abscess of trunk Dermatologic 1.15 1.04 – 1.28 0.00789 358 4375 exclusion phecode
686
Other local infections of skin and subcutaneous
Other local infections of skin and subcutaneous tissue
 Dermatologic 1.15 1.07 – 1.23 8.03e-05 807 9636 exclusion phecode
686.1 Carbuncle and furuncle Dermatologic 1.03 0.975 – 1.08 0.304 1475 17138 exclusion phecode
686.3 Pilonidal cyst Dermatologic 0.95 0.857 – 1.05 0.332 404 4550 exclusion phecode
686.4 Pyogenic granuloma Dermatologic 0.88 0.771 – 1 0.0572 255 2627 exclusion phecode
687 Symptoms affecting skin Dermatologic 1.12 1 – 1.24 0.0456 351 3979 exclusion phecode
687.1 Rash and other nonspecific skin eruption Dermatologic 1.02 0.967 – 1.08 0.415 1288 15623 exclusion phecode
687.2 Localized superficial swelling, mass, or lump Dermatologic 1.14 0.987 – 1.32 0.0747 195 2039 exclusion phecode
687.3 Changes in skin texture Dermatologic 1.16 0.908 – 1.47 0.238 71 794 exclusion phecode
687.4 Disturbance of skin sensation Dermatologic 1.03 0.984 – 1.08 0.196 1962 21730 exclusion phecode
689 Disorder of skin and subcutaneous tissue NOS Dermatologic 0.978 0.946 – 1.01 0.178 3950 41432 exclusion phecode
690 Erythematosquamous dermatosis Dermatologic 0.948 0.702 – 1.28 0.724 46 529 exclusion phecode
690.1 Seborrheic dermatitis Dermatologic 0.876 0.613 – 1.25 0.468 36 386 exclusion phecode
691 Congenital anomalies of skin Dermatologic 0.817 0.64 – 1.04 0.106 80 876 exclusion phecode
694 Dyschromia and Vitiligo Dermatologic 0.979 0.907 – 1.06 0.594 723 7202 exclusion phecode
694.1 Vitiligo Dermatologic 0.92 0.647 – 1.31 0.644 39 445 exclusion phecode
694.2 Other dyschromia Dermatologic 0.951 0.874 – 1.03 0.246 597 5704 exclusion phecode
694.3 Vascular disorders of skin Dermatologic 1.19 0.932 – 1.51 0.166 68 847 exclusion phecode
695 Erythematous conditions Dermatologic 0.985 0.934 – 1.04 0.584 1513 17392 exclusion phecode
695.1 Toxic erythema Dermatologic 1.09 0.853 – 1.4 0.489 66 829 exclusion phecode
695.2 Bullous dermatoses Dermatologic 0.947 0.758 – 1.18 0.633 87 966 exclusion phecode
695.21 Dermatitis herpetiformis Dermatologic 1.13 0.826 – 1.55 0.44 36 395 exclusion phecode
695.22 Pemphigus and pemphigoid Dermatologic 0.827 0.605 – 1.13 0.234 48 516 exclusion phecode
695.3 Rosacea Dermatologic 1.08 0.946 – 1.24 0.247 224 2212 exclusion phecode
695.4 Lupus (localized and systemic) Dermatologic 0.994 0.866 – 1.14 0.936 219 3148 exclusion phecode
695.41 Cutaneous lupus erythematosus Dermatologic 0.865 0.678 – 1.1 0.244 71 955 exclusion phecode
695.42 Systemic lupus erythematosus Dermatologic 0.976 0.839 – 1.14 0.758 179 2643 exclusion phecode
695.7 Prurigo and Lichen Dermatologic 0.967 0.884 – 1.06 0.467 527 5652 exclusion phecode
695.8 Other specified erythematous conditions Dermatologic 0.933 0.789 – 1.1 0.417 146 1752 exclusion phecode
695.81 Erythema nodosum Dermatologic 0.775 0.587 – 1.02 0.0725 55 604 exclusion phecode
695.9 Unspecified erythematous condition Dermatologic 0.981 0.867 – 1.11 0.765 280 3288 exclusion phecode
696 Psoriasis and related disorders Dermatologic 1 0.945 – 1.06 0.993 1320 16391 exclusion phecode
696.4 Psoriasis Dermatologic 1.01 0.952 – 1.07 0.796 1285 16044 exclusion phecode
696.41 Psoriasis vulgaris Dermatologic 1.01 0.942 – 1.07 0.869 954 12132 exclusion phecode
696.42 Psoriatic arthropathy Dermatologic 1.05 0.95 – 1.15 0.364 450 5291 exclusion phecode
697 Sarcoidosis Dermatologic 1.12 0.997 – 1.27 0.0561 268 4024 exclusion phecode
698 Pruritus and related conditions Dermatologic 1.03 0.947 – 1.13 0.47 550 5719 exclusion phecode
700 Corns and callosities Dermatologic 0.995 0.859 – 1.15 0.952 185 2154 exclusion phecode
701
Other hypertrophic and atrophic conditions of
Other hypertrophic and atrophic conditions of skin
 Dermatologic 1.01 0.971 – 1.04 0.737 3312 34327 exclusion phecode
701.1 Keratoderma, acquired Dermatologic 0.936 0.704 – 1.24 0.648 54 590 exclusion phecode
701.2 Scar conditions and fibrosis of skin Dermatologic 1.01 0.962 – 1.06 0.66 1716 17453 exclusion phecode
701.3 Circumscribed scleroderma Dermatologic 1.12 0.807 – 1.54 0.508 38 428 exclusion phecode
701.4 Keloid scar Dermatologic 0.969 0.823 – 1.14 0.702 162 1675 exclusion phecode
701.5 Abnormal granulation tissue Dermatologic 1.04 0.932 – 1.16 0.482 338 3396 exclusion phecode
701.6 Acquired acanthosis nigricans Dermatologic 1.02 0.798 – 1.31 0.869 64 767 exclusion phecode
702
Degenerative skin conditions and other
Degenerative skin conditions and other dermatoses
 Dermatologic 0.996 0.963 – 1.03 0.808 3821 38063 exclusion phecode
702.1 Actinic keratosis Dermatologic 0.987 0.939 – 1.04 0.589 1753 17669 exclusion phecode
702.2 Seborrheic keratosis Dermatologic 1 0.957 – 1.05 0.988 2208 21594 exclusion phecode
703 Diseases of nail, NOS Dermatologic 1.06 0.923 – 1.21 0.428 230 2525 exclusion phecode
703.1 Ingrowing nail Dermatologic 1.15 1.06 – 1.25 0.000499 620 7152 exclusion phecode
704 Diseases of hair and hair follicles Dermatologic 1.04 1.01 – 1.08 0.0112 3837 39206 exclusion phecode
704.1 Alopecia Dermatologic 0.947 0.76 – 1.18 0.632 83 992 exclusion phecode
704.8
Other specified diseases of hair and hair
Other specified diseases of hair and hair follicles
 Dermatologic 1.06 0.83 – 1.35 0.644 58 561 exclusion phecode
705 Disorders of sweat glands Dermatologic 1.05 0.881 – 1.24 0.61 139 1822 exclusion phecode
705.3 Hidradenitis Dermatologic 0.977 0.807 – 1.18 0.808 114 1494 exclusion phecode
705.8 Hyperhidrosis Dermatologic 1.16 1.05 – 1.29 0.00496 361 4228 exclusion phecode
706 Diseases of sebaceous glands Dermatologic 1.04 1.01 – 1.07 0.00399 6063 61421 exclusion phecode
706.1 Acne Dermatologic 1.46 1.13 – 1.89 0.0042 57 622 exclusion phecode
706.2 Sebaceous cyst Dermatologic 1.03 1 – 1.05 0.0546 6421 64821 exclusion phecode
707 Chronic ulcer of skin Dermatologic 1.05 0.978 – 1.12 0.185 823 13259 exclusion phecode
707.1 Decubitus ulcer Dermatologic 1.01 0.915 – 1.11 0.874 426 6025 exclusion phecode
709 Diffuse diseases of connective tissue Dermatologic 1.02 0.976 – 1.07 0.379 2182 24985 exclusion phecode
709.2 Sicca syndrome Dermatologic 1.1 0.972 – 1.24 0.132 260 3817 exclusion phecode
709.3 Systemic sclerosis Dermatologic 1.08 0.883 – 1.33 0.439 90 1293 exclusion phecode
709.6
Other specified diffuse diseases of connective
Other specified diffuse diseases of connective tissue
 Dermatologic 1.25 0.901 – 1.73 0.182 32 505 exclusion phecode
709.7 Unspecified diffuse connective tissue disease Dermatologic 1 0.954 – 1.05 0.969 1812 19648 exclusion phecode
710
Osteomyelitis, periostitis, and other
Osteomyelitis, periostitis, and other infections involving bone
 Musculoskeletal 1.07 0.95 – 1.2 0.27 290 4237 exclusion phecode
710.1 Osteomyelitis Musculoskeletal 1.05 0.933 – 1.19 0.394 266 3944 exclusion phecode
710.12 Chronic osteomyelitis Musculoskeletal 1.08 0.884 – 1.32 0.45 99 1413 exclusion phecode
710.19 Unspecified osteomyelitis Musculoskeletal 1.04 0.897 – 1.21 0.595 176 2796 exclusion phecode
711 Arthropathy associated with infections Musculoskeletal 1.08 0.948 – 1.22 0.257 246 3048 exclusion phecode
711.1 Pyogenic arthritis Musculoskeletal 1.11 0.957 – 1.28 0.174 183 2351 exclusion phecode
712 Infective connective tissue disorders Musculoskeletal 1.39 1.06 – 1.82 0.0177 46 569 exclusion phecode
713
Arthropathy associated with other disorders
Arthropathy associated with other disorders classified elsewhere
 Musculoskeletal 1.2 0.949 – 1.52 0.128 65 1078 exclusion phecode
713.5
Arthropathy associated with neurological
Arthropathy associated with neurological disorders
 Musculoskeletal 1.22 0.782 – 1.92 0.376 15 445 exclusion phecode
714
Rheumatoid arthritis and other inflammatory
Rheumatoid arthritis and other inflammatory polyarthropathies
 Musculoskeletal 1.03 0.989 – 1.07 0.154 2698 35492 exclusion phecode
714.1 Rheumatoid arthritis Musculoskeletal 1.02 0.981 – 1.07 0.292 2421 32196 exclusion phecode
715 Other inflammatory spondylopathies Musculoskeletal 0.992 0.931 – 1.06 0.817 1023 12060 exclusion phecode
715.1 Sacroiliitis NEC Musculoskeletal 1.07 0.85 – 1.35 0.553 72 897 exclusion phecode
715.2 Ankylosing spondylitis Musculoskeletal 1.07 0.965 – 1.18 0.203 379 4404 exclusion phecode
716 Other arthropathies Musculoskeletal 1.04 1.02 – 1.05 5.04e-07 23477 196989 exclusion phecode
716.1 Unspecified polyarthropathy or polyarthritis Musculoskeletal 1.05 1 – 1.09 0.0409 2074 25167 exclusion phecode
716.2 Unspecified monoarthritis Musculoskeletal 1.04 1.02 – 1.06 0.00016 9596 111168 exclusion phecode
716.9 Arthropathy NOS Musculoskeletal 1.03 1.02 – 1.05 2.02e-06 22494 194363 exclusion phecode
717 Polymyalgia Rheumatica Musculoskeletal 1.05 0.965 – 1.13 0.274 598 7700 exclusion phecode
720 Spinal stenosis Musculoskeletal 1.06 1.02 – 1.11 0.00763 2203 25800 exclusion phecode
721 Spondylosis and allied disorders Musculoskeletal 1.02 0.988 – 1.05 0.254 4838 55921 exclusion phecode
721.1 Spondylosis without myelopathy Musculoskeletal 1.02 0.985 – 1.06 0.246 3110 35929 exclusion phecode
721.2 Spondylosis with myelopathy Musculoskeletal 0.993 0.82 – 1.2 0.945 109 1333 exclusion phecode
721.8 Other allied disorders of spine Musculoskeletal 1.01 0.875 – 1.16 0.936 211 2495 exclusion phecode
722 Intervertebral disc disorders Musculoskeletal 1.04 1.01 – 1.07 0.00422 6074 66959 exclusion phecode
722.1 Displacement of intervertebral disc Musculoskeletal 1.07 0.96 – 1.18 0.23 377 3878 exclusion phecode
722.6 Degeneration of intervertebral disc Musculoskeletal 1.05 1 – 1.1 0.0353 1811 21082 exclusion phecode
722.8 Postlaminectomy syndrome Musculoskeletal 0.999 0.746 – 1.34 0.995 47 524 exclusion phecode
722.9 Other and unspecified disc disorder Musculoskeletal 1.05 1.01 – 1.09 0.0118 2998 32921 exclusion phecode
723 Other disorders of cervical region Musculoskeletal 1.06 0.951 – 1.19 0.285 335 3762 exclusion phecode
723.1 Torticollis Musculoskeletal 1.13 0.907 – 1.41 0.273 79 818 exclusion phecode
724 Other and unspecified disorders of back Musculoskeletal 1.06 0.999 – 1.11 0.053 1386 15228 exclusion phecode
724.1 Disorders of sacrum Musculoskeletal 1.03 0.921 – 1.16 0.572 307 3198 exclusion phecode
724.2 Disorders of coccyx Musculoskeletal 1.03 0.914 – 1.15 0.667 311 3212 exclusion phecode
724.8 Other symptoms referable to back Musculoskeletal 1.21 0.893 – 1.63 0.221 39 439 exclusion phecode
724.9 Other unspecified back disorders Musculoskeletal 1.06 0.994 – 1.13 0.0761 1061 11786 exclusion phecode
726 Peripheral enthesopathies and allied syndromes Musculoskeletal 1 0.98 – 1.02 0.977 10176 107805 exclusion phecode
726.1 Enthesopathy Musculoskeletal 1.01 0.98 – 1.03 0.681 6550 69785 exclusion phecode
726.2 Synoviopathy Musculoskeletal 0.86 0.755 – 0.979 0.0222 266 2591 exclusion phecode
726.3 Bursitis Musculoskeletal 1.02 0.934 – 1.11 0.712 564 6223 exclusion phecode
727 Other disorders of synovium, tendon, and bursa Musculoskeletal 1.01 0.982 – 1.04 0.5 5229 54739 exclusion phecode
727.1 Synovitis and tenosynovitis Musculoskeletal 0.999 0.953 – 1.05 0.978 1873 20440 exclusion phecode
727.2 Bursitis disorders Musculoskeletal 0.879 0.694 – 1.11 0.285 77 733 exclusion phecode
727.4 Ganglion and cyst of synovium, tendon, and bursa Musculoskeletal 1 0.962 – 1.05 0.862 2325 23560 exclusion phecode
727.5 Rupture of synovium Musculoskeletal 1.07 0.964 – 1.18 0.21 375 4137 exclusion phecode
727.6 Rupture of tendon, nontraumatic Musculoskeletal 0.999 0.874 – 1.14 0.983 242 2529 exclusion phecode
727.7 Contracture of tendon (sheath) Musculoskeletal 0.945 0.766 – 1.16 0.593 99 1022 exclusion phecode
728 Disorders of muscle, ligament, and fascia Musculoskeletal 0.991 0.951 – 1.03 0.665 2465 24188 exclusion phecode
728.2 Laxity of ligament or hypermobility syndrome Musculoskeletal 1.12 0.999 – 1.25 0.0529 308 3266 exclusion phecode
728.7 Fasciitis Musculoskeletal 1 0.961 – 1.04 0.997 2559 25266 exclusion phecode
728.71
Contracture of palmar fascia [Dupuytren's
Contracture of palmar fascia [Dupuytren's disease]
 Musculoskeletal 0.99 0.949 – 1.03 0.632 2348 22728 exclusion phecode
729 Other disorders of soft tissues Musculoskeletal 1.04 1.01 – 1.08 0.0149 3620 44027 exclusion phecode
729.1 Rheumatism, unspecified and fibrositis Musculoskeletal 1.06 0.974 – 1.14 0.186 655 7817 exclusion phecode
729.3 Panniculitis Musculoskeletal 0.934 0.738 – 1.18 0.568 77 746 exclusion phecode
731
Osteitis deformans and osteopathies associated
Osteitis deformans and osteopathies associated with other disorders classified elsewhere
 Musculoskeletal 1.03 0.886 – 1.19 0.728 196 2119 exclusion phecode
731.1 Osteitis deformans [Paget's disease of bone] Musculoskeletal 1.02 0.878 – 1.19 0.795 186 2012 exclusion phecode
732 Osteochondropathies Musculoskeletal 0.927 0.827 – 1.04 0.193 344 3573 exclusion phecode
732.1 Juvenile osteochondrosis Musculoskeletal 0.814 0.681 – 0.973 0.024 145 1541 exclusion phecode
732.7 Osteochondritis dissecans Musculoskeletal 1.01 0.74 – 1.37 0.962 43 451 exclusion phecode
733 Other disorders of bone and cartilage Musculoskeletal 0.995 0.938 – 1.06 0.873 1196 13157 exclusion phecode
733.2 Cyst of bone Musculoskeletal 1.02 0.886 – 1.16 0.826 225 2302 exclusion phecode
733.4 Aseptic necrosis of bone Musculoskeletal 1.06 0.947 – 1.19 0.312 316 3935 exclusion phecode
733.6 Costochondritis Musculoskeletal 1.08 0.876 – 1.34 0.463 85 939 exclusion phecode
733.8 Malunion and nonunion of fracture Musculoskeletal 1.02 0.946 – 1.09 0.651 820 9217 exclusion phecode
733.9 Chondromalacia Musculoskeletal 0.844 0.682 – 1.04 0.117 93 930 exclusion phecode
735 Acquired foot deformities Musculoskeletal 0.99 0.966 – 1.02 0.449 6982 71984 exclusion phecode
735.1 Flat foot Musculoskeletal 0.972 0.809 – 1.17 0.762 122 1423 exclusion phecode
735.2 Acquired toe deformities Musculoskeletal 1.01 0.974 – 1.04 0.664 3551 37254 exclusion phecode
735.21 Hammer toe (acquired) Musculoskeletal 1.06 1 – 1.12 0.0418 1329 14089 exclusion phecode
735.23 Hallux rigidus Musculoskeletal 0.983 0.924 – 1.05 0.586 1142 11378 exclusion phecode
735.3 Hallux valgus (Bunion) Musculoskeletal 0.991 0.962 – 1.02 0.525 4947 50311 exclusion phecode
736 Other acquired deformities of limbs Musculoskeletal 1.02 0.953 – 1.08 0.622 1006 11671 exclusion phecode
736.2 Acquired deformities of finger Musculoskeletal 1.06 0.907 – 1.24 0.461 171 1820 exclusion phecode
737 Curvature of spine Musculoskeletal 1.01 0.932 – 1.09 0.842 691 8211 exclusion phecode
737.3 Kyphoscoliosis and scoliosis Musculoskeletal 1.01 0.932 – 1.09 0.804 649 7702 exclusion phecode
738 Other acquired musculoskeletal deformity Musculoskeletal 0.967 0.912 – 1.02 0.254 1249 13821 exclusion phecode
738.4 Acquired spondylolisthesis Musculoskeletal 0.936 0.876 – 1 0.0547 955 10770 exclusion phecode
739 Contracture of joint Musculoskeletal 1.01 0.901 – 1.13 0.855 306 3667 exclusion phecode
740 Osteoarthrosis Musculoskeletal 1.03 1.01 – 1.04 0.000364 17376 166682 exclusion phecode
740.1 Osteoarthritis; localized Musculoskeletal 1.03 1.01 – 1.05 0.00107 11040 119049 exclusion phecode
740.11 Osteoarthrosis, localized, primary Musculoskeletal 1.03 1 – 1.06 0.0321 5522 62406 exclusion phecode
740.12 Osteoarthrosis, localized, secondary Musculoskeletal 1.02 0.895 – 1.17 0.73 227 2490 exclusion phecode
740.2 Osteoarthrosis, generalized Musculoskeletal 0.98 0.877 – 1.09 0.716 343 4215 exclusion phecode
740.9 Osteoarthrosis NOS Musculoskeletal 1.02 0.996 – 1.04 0.1 7456 87250 exclusion phecode
741 Symptoms and disorders of the joints Musculoskeletal 1.04 1 – 1.09 0.051 2324 25926 exclusion phecode
741.1 Ankylosis of joint Musculoskeletal 1.04 0.811 – 1.33 0.758 68 725 exclusion phecode
741.2 Stiffness of joint Musculoskeletal 1.04 0.946 – 1.15 0.401 450 4582 exclusion phecode
741.3 Difficulty in walking Musculoskeletal 1.2 0.968 – 1.48 0.0968 79 1092 exclusion phecode
741.4 Joint effusions Musculoskeletal 1.08 1.01 – 1.16 0.0298 843 10050 exclusion phecode
741.5 Hemarthrosis Musculoskeletal 1.21 0.953 – 1.52 0.118 68 795 exclusion phecode
741.6 Villonodular synovitis Musculoskeletal 0.889 0.637 – 1.24 0.488 37 413 exclusion phecode
742 Derangement of joint, non-traumatic Musculoskeletal 1.02 0.976 – 1.07 0.37 2079 21769 exclusion phecode
742.1 Loose body in joint Musculoskeletal 1.13 0.991 – 1.29 0.0686 236 2417 exclusion phecode
742.2
Pathological, developmental or recurrent
Pathological, developmental or recurrent dislocation
 Musculoskeletal 1.02 0.806 – 1.3 0.856 75 790 exclusion phecode
742.8 Articular cartilage disorder Musculoskeletal 1.1 0.985 – 1.23 0.0907 350 3839 exclusion phecode
742.9 Other derangement of joint Musculoskeletal 0.996 0.944 – 1.05 0.894 1489 15364 exclusion phecode
743
Osteoporosis, osteopenia and pathological
Osteoporosis, osteopenia and pathological fracture
 Musculoskeletal 1.01 0.985 – 1.04 0.354 4923 54050 exclusion phecode
743.1 Osteoporosis Musculoskeletal 1 0.973 – 1.04 0.778 4147 45488 exclusion phecode
743.11 Osteoporosis NOS Musculoskeletal 1 0.969 – 1.04 0.895 3611 39824 exclusion phecode
743.13 Other specified osteoporosis Musculoskeletal 1.03 0.92 – 1.15 0.613 319 3471 exclusion phecode
743.2 Pathologic fracture Musculoskeletal 1.03 0.913 – 1.16 0.628 281 3692 exclusion phecode
743.9
Osteopenia or other disorder of bone and
Osteopenia or other disorder of bone and cartilage
 Musculoskeletal 1.06 0.973 – 1.15 0.184 583 6068 exclusion phecode
745 Pain in joint Musculoskeletal 1.02 0.995 – 1.05 0.107 5204 58798 exclusion phecode
747 Cardiac and circulatory congenital anomalies Congenital Anomalies 0.974 0.926 – 1.02 0.308 1632 19231 exclusion phecode
747.1 Cardiac congenital anomalies Congenital Anomalies 0.971 0.921 – 1.02 0.272 1509 17983 exclusion phecode
747.11 Cardiac shunt/ heart septal defect Congenital Anomalies 0.902 0.812 – 1 0.0536 413 4430 exclusion phecode
747.12 Valvular heart disease/ heart chambers Congenital Anomalies 1.01 0.854 – 1.2 0.906 152 1731 exclusion phecode
747.13 Congenital anomalies of great vessels Congenital Anomalies 1 0.941 – 1.07 0.886 929 11802 exclusion phecode
747.2
Congenital anomalies of peripheral vascular
Congenital anomalies of peripheral vascular system
 Congenital Anomalies 1 0.837 – 1.2 0.976 116 1230 exclusion phecode
748 Anomalies of respiratory system, congenital Congenital Anomalies 1.19 0.847 – 1.68 0.315 35 360 exclusion phecode
749 Congenital anomalies of face and neck Congenital Anomalies 1.07 0.936 – 1.23 0.311 226 2300 exclusion phecode
750 Digestive congenital anomalies Congenital Anomalies 0.989 0.897 – 1.09 0.833 420 4857 exclusion phecode
750.1 Upper gastrointestinal congenital anomalies Congenital Anomalies 1.07 0.932 – 1.23 0.342 206 2222 exclusion phecode
750.13 Congenital anomalies of mouth/tongue Congenital Anomalies 0.96 0.8 – 1.15 0.664 122 1296 exclusion phecode
750.2 Lower gastrointestinal congenital anomalies Congenital Anomalies 0.947 0.823 – 1.09 0.448 210 2597 exclusion phecode
750.21 Congenital anomalies of intestine Congenital Anomalies 0.916 0.777 – 1.08 0.291 158 1622 exclusion phecode
750.22
Congenital anomaly of gallbladder, bile ducts
Congenital anomaly of gallbladder, bile ducts, liver, pancreas
 Congenital Anomalies 0.844 0.629 – 1.13 0.257 46 877 exclusion phecode
751 Genitourinary congenital anomalies Congenital Anomalies 0.983 0.918 – 1.05 0.616 905 11418 exclusion phecode
751.1 Congenital anomalies of genital organs Congenital Anomalies 0.939 0.856 – 1.03 0.174 537 5406 exclusion phecode
751.11 Congenital anomalies of female genital organs Congenital Anomalies 0.956 0.858 – 1.07 0.424 372 3782 exclusion phecode
751.12 Congenital anomalies of male genital organs Congenital Anomalies 0.943 0.798 – 1.11 0.492 155 1519 exclusion phecode
751.2 Congenital anomalies of urinary system Congenital Anomalies 1.04 0.942 – 1.16 0.407 370 6043 exclusion phecode
751.21 Cystic kidney disease Congenital Anomalies 1.26 1.07 – 1.48 0.00631 133 3003 exclusion phecode
751.22 Other specified congenital anomalies of kidney Congenital Anomalies 0.964 0.832 – 1.12 0.622 186 2457 exclusion phecode
752 Nervous system congenital anomalies Congenital Anomalies 0.897 0.781 – 1.03 0.125 231 2580 exclusion phecode
752.1 Neural tube defects Congenital Anomalies 1.01 0.86 – 1.18 0.944 180 2025 exclusion phecode
752.11 Spina bifida Congenital Anomalies 0.987 0.83 – 1.17 0.884 145 1665 exclusion phecode
752.2
Other specified congenital anomalies of nervous
Other specified congenital anomalies of nervous system
 Congenital Anomalies 0.672 0.493 – 0.917 0.0122 54 593 exclusion phecode
753 Congenital anomalies of the eye Congenital Anomalies 1.03 0.82 – 1.29 0.805 81 953 exclusion phecode
753.1 Congenital cataract and lens anomalies Congenital Anomalies 0.971 0.725 – 1.3 0.843 47 581 exclusion phecode
754 Congenital musculoskeletal deformities of spine Congenital Anomalies 0.825 0.647 – 1.05 0.121 72 859 exclusion phecode
755 Congenital anomalies of limbs Congenital Anomalies 0.997 0.887 – 1.12 0.956 306 3285 exclusion phecode
755.1 Congenital deformities of feet Congenital Anomalies 0.985 0.835 – 1.16 0.861 153 1554 exclusion phecode
755.6
Other congenital anomalies of lower limb
Other congenital anomalies of lower limb, including pelvic girdle
 Congenital Anomalies 0.939 0.775 – 1.14 0.516 114 1299 exclusion phecode
755.61 Congenital hip dysplasia and deformity Congenital Anomalies 0.856 0.673 – 1.09 0.206 76 870 exclusion phecode
756 Other congenital musculoskeletal anomalies Congenital Anomalies 0.962 0.87 – 1.06 0.454 414 4400 exclusion phecode
756.3
Congenital anomalies of muscle, tendon, fascia
Congenital anomalies of muscle, tendon, fascia, and connective tissue
 Congenital Anomalies 0.95 0.732 – 1.23 0.697 60 635 exclusion phecode
756.5 Congenital osteodystrophies Congenital Anomalies 0.978 0.869 – 1.1 0.711 297 3254 exclusion phecode
758 Chromosomal anomalies and genetic disorders Congenital Anomalies 1.17 0.947 – 1.44 0.148 88 1308 exclusion phecode
758.1 Chromosomal anomalies Congenital Anomalies 1.24 0.906 – 1.7 0.18 36 648 exclusion phecode
759 Other and unspecified congenital anomalies Congenital Anomalies 1.01 0.851 – 1.2 0.915 133 1586 exclusion phecode
759.1 Anomalies of endocrine glands, congenital Congenital Anomalies 1.12 0.882 – 1.42 0.354 64 704 exclusion phecode
760 Back pain Symptoms 1.03 1.01 – 1.06 0.0102 7241 82599 exclusion phecode
761 Cervicalgia Symptoms 0.976 0.92 – 1.03 0.412 1226 13386 exclusion phecode
764 Sciatica Symptoms 1.03 0.98 – 1.09 0.235 1561 17542 exclusion phecode
766 Neuralgia, neuritis, and radiculitis NOS Symptoms 1.06 0.984 – 1.14 0.129 749 8615 exclusion phecode
770 Myalgia and myositis unspecified Symptoms 1.09 0.992 – 1.21 0.0713 414 4712 exclusion phecode
771 Musculoskeletal symptoms referable to limbs Symptoms 0.981 0.9 – 1.07 0.657 563 6326 exclusion phecode
771.1 Swelling of limb Symptoms 1.05 1.01 – 1.09 0.0231 2688 33176 exclusion phecode
772 Symptoms of the muscles Symptoms 1.03 0.933 – 1.14 0.569 423 4807 exclusion phecode
773 Pain in limb Symptoms 0.996 0.964 – 1.03 0.794 3953 45671 exclusion phecode
780 Hypothermia/Chills Symptoms 0.97 0.792 – 1.19 0.765 97 1231 exclusion phecode
781
Symptoms involving nervous and musculoskeletal
Symptoms involving nervous and musculoskeletal systems
 Symptoms 1.08 1.02 – 1.15 0.00635 1200 13658 exclusion phecode
782.3 Edema Symptoms 1.07 0.998 – 1.15 0.0564 745 11377 exclusion phecode
782.6 Pallor and flushing Symptoms 0.946 0.78 – 1.15 0.573 119 1247 exclusion phecode
783 Fever of unknown origin Symptoms 1.04 0.997 – 1.08 0.0724 2439 28217 exclusion phecode
785 Abdominal pain Symptoms 1.02 1 – 1.03 0.00902 28423 225671 exclusion phecode
788 Syncope and collapse Symptoms 1.02 0.988 – 1.04 0.276 5658 63507 exclusion phecode
789 Nausea and vomiting Symptoms 1.02 0.999 – 1.05 0.0641 7405 85578 exclusion phecode
790 Nonspecific findings on examination of blood Symptoms 1.08 0.878 – 1.34 0.454 87 1038 exclusion phecode
790.1 Elevated sedimentation rate Symptoms 0.892 0.637 – 1.25 0.504 38 573 exclusion phecode
790.6 Other abnormal blood chemistry Symptoms 1.01 0.977 – 1.04 0.54 3644 41750 exclusion phecode
791 Gangrene Symptoms 1.06 0.936 – 1.2 0.351 244 3880 exclusion phecode
792
Abnormal Papanicolaou smear of cervix and
Abnormal Papanicolaou smear of cervix and cervical HPV
 Symptoms 0.933 0.735 – 1.18 0.569 76 727 exclusion phecode
793
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of musculoskeletal system
 Symptoms 1.02 0.826 – 1.27 0.823 85 945 exclusion phecode
793.2
Nonspecific abnormal findings on radiological
Nonspecific abnormal findings on radiological and other examination of other intrathoracic organs (echocardiogram, etc)
 Symptoms 1.02 0.914 – 1.14 0.712 349 3993 exclusion phecode
794
Abnormal results of other function studies
Abnormal results of other function studies (bladder, pancreas, placenta, spleen, etc)
 Symptoms 0.902 0.726 – 1.12 0.352 96 1018 exclusion phecode
797 Shock Symptoms 1.06 0.853 – 1.32 0.593 77 1011 exclusion phecode
797.1 Cardiogenic shock Symptoms 1.05 0.785 – 1.39 0.762 46 639 exclusion phecode
798 Malaise and fatigue Symptoms 1.02 0.974 – 1.06 0.425 2176 24992 exclusion phecode
798.1 Chronic fatigue syndrome Symptoms 1.01 0.915 – 1.11 0.858 447 4590 exclusion phecode
800 Fracture of lower limb Injuries & Poisonings 1.01 0.978 – 1.04 0.626 4863 50960 exclusion phecode
800.1 Fracture of neck of femur Injuries & Poisonings 1.02 0.959 – 1.08 0.566 1178 12464 exclusion phecode
800.2 Fracture of unspecified part of femur Injuries & Poisonings 1.13 0.931 – 1.36 0.219 105 1222 exclusion phecode
800.3 Fracture of tibia and fibula Injuries & Poisonings 1.04 0.984 – 1.09 0.182 1569 16175 exclusion phecode
800.4 Fracture of patella Injuries & Poisonings 1.08 0.992 – 1.18 0.0747 532 5519 exclusion phecode
801 Fracture of ankle and foot Injuries & Poisonings 1.01 0.961 – 1.07 0.653 1561 16475 exclusion phecode
801.1 Fracture of foot Injuries & Poisonings 1.06 0.998 – 1.12 0.0602 1313 13664 exclusion phecode
802 Fracture of pelvis Injuries & Poisonings 1.04 0.945 – 1.14 0.444 488 5176 exclusion phecode
803 Fracture of upper limb Injuries & Poisonings 1.01 0.987 – 1.04 0.331 6088 61074 exclusion phecode
803.1 Fracture of humerus Injuries & Poisonings 1.04 0.978 – 1.1 0.213 1139 12241 exclusion phecode
803.2 Fracture of radius and ulna Injuries & Poisonings 1.02 0.986 – 1.05 0.252 3930 38861 exclusion phecode
803.3 Fracture of clavicle or scapula Injuries & Poisonings 1.02 0.955 – 1.08 0.628 1111 10928 exclusion phecode
804 Fracture of hand or wrist Injuries & Poisonings 0.995 0.955 – 1.04 0.808 2464 24889 exclusion phecode
805
Fracture of vertebral column without mention of
Fracture of vertebral column without mention of spinal cord injury
 Injuries & Poisonings 1.03 0.964 – 1.1 0.378 927 9901 exclusion phecode
807 Fracture of ribs Injuries & Poisonings 0.972 0.889 – 1.06 0.534 526 5437 exclusion phecode
809 Fracture of unspecified bones Injuries & Poisonings 1.04 0.97 – 1.11 0.281 887 9451 exclusion phecode
817 Concussion Injuries & Poisonings 1.12 0.968 – 1.3 0.125 180 1822 exclusion phecode
818 Intracranial hemorrhage (injury) Injuries & Poisonings 1.07 0.959 – 1.19 0.228 333 3559 exclusion phecode
819
Skull and face fracture and other intercranial
Skull and face fracture and other intercranial injury
 Injuries & Poisonings 1.02 0.979 – 1.07 0.316 2173 22133 exclusion phecode
823 Torus fracture Injuries & Poisonings 1.06 1 – 1.12 0.0473 1226 12588 exclusion phecode
830 Dislocation Injuries & Poisonings 0.998 0.947 – 1.05 0.939 1519 15494 exclusion phecode
835 Internal derangement of knee Injuries & Poisonings 1.02 0.997 – 1.04 0.0972 10995 112652 exclusion phecode
836 Traumatic arthropathy Injuries & Poisonings 1.01 0.904 – 1.12 0.92 366 3840 exclusion phecode
840 Sprains and strains Injuries & Poisonings 0.972 0.872 – 1.08 0.603 358 3560 exclusion phecode
850 Hemorrhage or hematoma complicating a procedure Injuries & Poisonings 1.03 0.996 – 1.07 0.0787 3428 38344 exclusion phecode
851
Complications of transplants and reattached
Complications of transplants and reattached limbs
 Injuries & Poisonings 0.967 0.782 – 1.19 0.755 94 1115 exclusion phecode
853 Complication of colostomy or enterostomy Injuries & Poisonings 1.01 0.893 – 1.14 0.867 276 3525 exclusion phecode
854
Complications of cardiac/vascular device
Complications of cardiac/vascular device, implant, and graft
 Injuries & Poisonings 1.02 0.952 – 1.09 0.572 866 12213 exclusion phecode
857
Mechanical complication of unspecified
Mechanical complication of unspecified genitourinary device, implant, and graft
 Injuries & Poisonings 0.968 0.898 – 1.04 0.402 734 8833 exclusion phecode
858 Complication of internal orthopedic device Injuries & Poisonings 0.991 0.947 – 1.04 0.717 1936 22544 exclusion phecode
859
Complication due to other implant and internal
Complication due to other implant and internal device
 Injuries & Poisonings 1.01 0.969 – 1.06 0.563 2013 23394 exclusion phecode
860 Bone marrow or stem cell transplant Neoplasms 1.23 0.911 – 1.66 0.178 40 530 exclusion phecode
870 Open wounds of head; neck; and trunk Injuries & Poisonings 1.01 0.972 – 1.06 0.537 2338 25149 exclusion phecode
870.1 Open wound or laceration of eye or eyelid Injuries & Poisonings 0.937 0.803 – 1.09 0.411 183 1967 exclusion phecode
870.2 Open wound of ear Injuries & Poisonings 1.01 0.841 – 1.21 0.907 125 1439 exclusion phecode
870.3 Other open wound of head and face Injuries & Poisonings 1.04 0.992 – 1.09 0.108 1943 20767 exclusion phecode
870.4 Open wound of nose and sinus Injuries & Poisonings 1.03 0.876 – 1.22 0.696 148 1535 exclusion phecode
870.6 Open wound of neck Injuries & Poisonings 0.896 0.675 – 1.19 0.446 48 511 exclusion phecode
871 Open wounds of extremities Injuries & Poisonings 1.03 0.992 – 1.07 0.123 2888 29962 exclusion phecode
871.1 Open wound of hand except finger(s) Injuries & Poisonings 0.952 0.685 – 1.32 0.772 41 369 exclusion phecode
871.2 Open wound of finger(s) Injuries & Poisonings 1.13 0.868 – 1.46 0.369 62 656 exclusion phecode
871.3 Open wound of foot except toe(s) alone Injuries & Poisonings 1.05 0.874 – 1.26 0.613 118 1315 exclusion phecode
872 Traumatic amputation Injuries & Poisonings 1.02 0.919 – 1.14 0.674 349 3368 exclusion phecode
873 Broken tooth Injuries & Poisonings 1.15 0.983 – 1.35 0.081 158 1673 exclusion phecode
874 Complication of amputation stump Injuries & Poisonings 1.06 0.858 – 1.31 0.592 87 1237 exclusion phecode
905
Late effects of musculoskeletal and connective
Late effects of musculoskeletal and connective tissue injuries
 Injuries & Poisonings 1.17 0.964 – 1.42 0.112 113 1185 exclusion phecode
907 Injuries to the nervous system Injuries & Poisonings 1.01 0.946 – 1.08 0.719 910 9756 exclusion phecode
915 Superficial injury without mention of infection Injuries & Poisonings 1.02 0.983 – 1.06 0.269 2732 30875 exclusion phecode
916 Contusion Injuries & Poisonings 1.01 0.943 – 1.08 0.833 958 10427 exclusion phecode
930 Allergic reaction to food Injuries & Poisonings 0.954 0.797 – 1.14 0.604 134 1399 exclusion phecode
938 Dermatitis due to solar radiation Injuries & Poisonings 1.01 0.89 – 1.15 0.875 250 2641 exclusion phecode
938.2 Chronic dermatitis due to solar radiation Injuries & Poisonings 0.946 0.811 – 1.1 0.485 168 1712 exclusion phecode
939
Atopic/contact dermatitis due to other or
Atopic/contact dermatitis due to other or unspecified
 Dermatologic 1.02 0.963 – 1.08 0.545 1350 15276 exclusion phecode
941 Adverse reaction to serum or vaccine Injuries & Poisonings 1.16 0.982 – 1.37 0.08 152 1568 exclusion phecode
942 Infusion and transfusion reaction Injuries & Poisonings 0.912 0.707 – 1.18 0.477 62 732 exclusion phecode
946 Anaphylactic shock NOS Injuries & Poisonings 1.01 0.905 – 1.13 0.821 333 4070 exclusion phecode
947 Urticaria Injuries & Poisonings 1.15 1.02 – 1.31 0.0253 249 2770 exclusion phecode
949 Allergies, other Injuries & Poisonings 0.941 0.832 – 1.06 0.334 280 3065 exclusion phecode
952
Spinal cord injury without evidence of spinal
Spinal cord injury without evidence of spinal bone injury
 Injuries & Poisonings 0.975 0.865 – 1.1 0.685 296 3088 exclusion phecode
957 Injury to other and unspecified nerves Injuries & Poisonings 0.929 0.789 – 1.09 0.378 158 1935 exclusion phecode
958
Certain early complications of trauma or
Certain early complications of trauma or procedure
 Injuries & Poisonings 1.04 0.929 – 1.17 0.491 310 3587 exclusion phecode
958.1 Postoperative shock Injuries & Poisonings 1.07 0.754 – 1.53 0.698 30 385 exclusion phecode
958.2 Traumatic and surgical subcutaneous emphysema Injuries & Poisonings 0.751 0.555 – 1.02 0.0632 51 506 exclusion phecode
960 Poisoning by antibiotics Injuries & Poisonings 1.02 1.01 – 1.04 0.0126 12268 135935 exclusion phecode
960.2 Allergy/adverse effect of penicillin Injuries & Poisonings 1.03 1.01 – 1.05 0.00754 10735 118729 exclusion phecode
961 Poisoning by other anti-infectives Injuries & Poisonings 1.07 0.941 – 1.21 0.308 253 3125 exclusion phecode
961.1 Poisoning/allergy of sulfonamides Injuries & Poisonings 1 0.918 – 1.09 0.996 575 6701 exclusion phecode
962 Poisoning by hormones and synthetic substitutes Injuries & Poisonings 1.12 0.97 – 1.29 0.124 192 2752 exclusion phecode
962.3
Hormones and synthetic substitutes causing
Hormones and synthetic substitutes causing adverse effects in therapeutic use
 Injuries & Poisonings 1.11 0.96 – 1.28 0.16 188 2693 exclusion phecode
963 Poisoning by primarily systemic agents Injuries & Poisonings 0.948 0.799 – 1.12 0.541 148 1787 exclusion phecode
964
Poisoning by agents primarily affecting blood
Poisoning by agents primarily affecting blood constituents
 Injuries & Poisonings 1.14 0.959 – 1.35 0.139 121 1978 exclusion phecode
964.1 Anticoagulants causing adverse effects Injuries & Poisonings 1.18 0.987 – 1.41 0.0691 116 1929 exclusion phecode
965
Poisoning by analgesics, antipyretics, and
Poisoning by analgesics, antipyretics, and antirheumatics
 Injuries & Poisonings 1.04 1 – 1.07 0.0293 3968 45867 exclusion phecode
965.1
Opiates and related narcotics causing adverse
Opiates and related narcotics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.02 0.947 – 1.1 0.593 758 8661 exclusion phecode
965.2
Antirheumatics causing adverse effects in
Antirheumatics causing adverse effects in therapeutic use
 Injuries & Poisonings 1.08 0.969 – 1.21 0.159 334 3867 exclusion phecode
965.3
Salicylates causing adverse effects in
Salicylates causing adverse effects in therapeutic use
 Injuries & Poisonings 0.896 0.786 – 1.02 0.0996 253 2948 exclusion phecode
966
Poisoning by anticonvulsants and
Poisoning by anticonvulsants and anti-Parkinsonism drugs
 Injuries & Poisonings 1.08 0.967 – 1.2 0.174 347 4037 exclusion phecode
967
Adverse effects of sedatives or other central
Adverse effects of sedatives or other central nervous system depressants and anesthetics
 Injuries & Poisonings 1.08 0.972 – 1.19 0.159 404 4411 exclusion phecode
969 Poisoning by psychotropic agents Injuries & Poisonings 1.06 1 – 1.12 0.0457 1325 15609 exclusion phecode
971
Poisoning by drugs primarily affecting the
Poisoning by drugs primarily affecting the autonomic nervous system
 Injuries & Poisonings 1.03 0.852 – 1.24 0.782 121 1510 exclusion phecode
972
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the cardiovascular system
 Injuries & Poisonings 1.07 0.915 – 1.26 0.388 157 2049 exclusion phecode
972.6 Antihypertensive agents causing adverse effects Injuries & Poisonings 0.947 0.718 – 1.25 0.702 51 670 exclusion phecode
973
Poisoning by agents primarily affecting the
Poisoning by agents primarily affecting the gastrointestinal system
 Injuries & Poisonings 1.3 1.02 – 1.65 0.0372 66 835 exclusion phecode
974
Poisoning by water, mineral, and uric acid
Poisoning by water, mineral, and uric acid metabolism drugs
 Injuries & Poisonings 1.07 0.777 – 1.48 0.673 35 711 exclusion phecode
975
Poisoning by agents primarily acting on the
Poisoning by agents primarily acting on the smooth and skeletal muscles and respiratory system
 Injuries & Poisonings 0.838 0.612 – 1.15 0.273 41 509 exclusion phecode
976
Poisoning by agents primarily affecting skin &
Poisoning by agents primarily affecting skin & mucous membrane, ophthalmological, otorhinolaryngological, & dental drugs
 Injuries & Poisonings 1.16 0.827 – 1.61 0.396 39 449 exclusion phecode
977 Personal history of allergy to medicinal agents Injuries & Poisonings 0.936 0.786 – 1.11 0.456 143 1740 exclusion phecode
979 Adverse drug events and drug allergies Injuries & Poisonings 0.967 0.878 – 1.06 0.489 458 5403 exclusion phecode
981
Toxic effect of (non-ethyl) alcohol and
Toxic effect of (non-ethyl) alcohol and petroleum and other solvents
 Injuries & Poisonings 0.964 0.811 – 1.15 0.676 136 1611 exclusion phecode
986 Toxic effect of carbon monoxide Injuries & Poisonings 0.913 0.679 – 1.23 0.549 45 460 exclusion phecode
987 Toxic effect of other gases, fumes, or vapors Injuries & Poisonings 1.05 0.821 – 1.35 0.68 61 764 exclusion phecode
988 Toxic effect of noxious substances eaten as food Injuries & Poisonings 0.847 0.674 – 1.06 0.155 86 877 exclusion phecode
989
Toxic effect of other substances, chiefly
Toxic effect of other substances, chiefly nonmedicinal as to source
 Injuries & Poisonings 0.905 0.683 – 1.2 0.484 53 617 exclusion phecode
990 Effects radiation NOS Injuries & Poisonings 1.01 0.961 – 1.05 0.811 2013 21824 exclusion phecode
994 Sepsis and SIRS Injuries & Poisonings 1 0.954 – 1.06 0.89 1560 21063 exclusion phecode
994.2 Sepsis Injuries & Poisonings 1 0.954 – 1.06 0.89 1560 21063 exclusion phecode
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